LOCUS       DAVBOG010000001        81140 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.001, whole genome shotgun sequence.
ACCESSION   DAVBOG010000001 DAVBOG010000000
VERSION     DAVBOG010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 81140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 81140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..81140
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.001"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(72..620)
                     /locus_tag="VQ865_000001"
     CDS             complement(72..620)
                     /locus_tag="VQ865_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF-type riboflavin transporter
                     substrate-binding protein"
                     /protein_id="HET3134438.1"
                     /translation="MEIKFTIKQVVAVGIGAALFVVIGMINIPTPVPNTSIQLQYAVQ
                     ALLSIIFGPIIGLLVGLIGHAIKDSLAGYGLWWTWIIASGLFGLVVGLFRKYVRVING
                     VFDWKDILIFNLIQLLANALVWGVLAPLGDVVIYQEAAEKVFAQGIVAGIANGVSVAI
                     AGTLLLLAYAGTQTRAGSLKKD"
     gene            complement(635..1483)
                     /locus_tag="VQ865_000002"
     CDS             complement(635..1483)
                     /locus_tag="VQ865_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HET3134439.1"
                     /translation="MNNNLLVLQSDFGLVDGAVSAMIGVALEESPTLKIHHLTHDITP
                     YNIFEGSYRLFQTVDYWPEGTTFVSVVDPGVGSKRKSVVAKTAKNQYIVTPDNGTLSF
                     IKKHVGIVAIREISEVANRRQNTEHSYTFHGRDVYAYTGAKLASGHITFEEVGPELSV
                     EQIVELPVVATIIEDHLVKGAIDILDVRFGSLWTSITREEFYKLEPEFGDRFEVTIYH
                     ADMLVYQNQVVYGKSFADVRIGQPILYINSLYRLGLAINQGSFAKAYNVGVGSSWTIE
                     IKKIEG"
     gene            1671..3020
                     /gene="trkA"
                     /locus_tag="VQ865_000003"
     CDS             1671..3020
                     /gene="trkA"
                     /locus_tag="VQ865_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HET3134440.1"
                     /translation="MKIILVGGGKVGFALCRSLVAEKHDVLLIEQDEAVLNHIVNRFD
                     IIGILGNGADFAILEQASVQDCDIFIALTEHDEVNMIAAVLAKKMGAKETIVRVRNPE
                     YSNSYFKEKNILGFSLIVNPELLAARAIANIIDFPNALSVERFAGGRVSLMEFVVKST
                     SGLCQMPISDFRKKFGNVIVCAIERDHQIIIPSGDMTVQDKDRIFVTGNRVDMILFHN
                     YFKSRAVKSLLIVGAGRIAYYLLGILKDSRIDTKVIEINPEIASFFSEKFPNLYIVQG
                     DGTAKDILLEESAQHYDAVATLTGVDEENLITSMFLDRVGVQKNITKVNRTSLLEIIN
                     APDFSSIITPKSIAVDTIMHFIRGRVNAQYSDLQAMHHLANGQIETLQFHIKEANKMT
                     AKPLSQLKLKKGVLIAAIIRKGKTIFPTGEDMLEVGDKLLVTTLLPNITKIYDLIAR"
     gene            3024..4463
                     /locus_tag="VQ865_000004"
     CDS             3024..4463
                     /locus_tag="VQ865_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3134441.1"
                     /translation="MNKSMIRYLLSKLLLIEAVLLLVPVAIAVYYRESSQVFTALFST
                     IGILVLLGGSGSLQKPKNQRIYAKEGVLIVALCWILWSFFGGLPFVFSGQIPSVIDAF
                     FEISSGFTTTGASILNDISVLSRSLLFWRSFTHLIGGMGVLVFALAIMDNAKNSHLEV
                     MKAEVPGPVFGKVVSKLKNTAQILYLLYLALFSLFVIIYYLAGMPLYDSFVIAMGTAG
                     TGGFTVYNDGIAHYGSSLITYLVSIGVLVFGVNFNLYYYLMLRRIKAFFGDEELRAYL
                     VIVLVSTGLISLNTLYLYPGFSKSFEMTFFQVSNIITTTGFGYGDITNWPLFSQFILL
                     FLMAIGGSAGSTAGGLKIIRGLILSKIAKNQILSILSPHRVLTLHVNKTVIDKDTQHK
                     ILKYFVIYAMILLALIFIVSLDSNDFLVVTSAVFSCFNNIGPILGTTSSFSIFSPISK
                     ILLSFAMIAGRLEIYPILLLFMKRTWSKR"
     gene            complement(4589..6268)
                     /locus_tag="VQ865_000005"
     CDS             complement(4589..6268)
                     /locus_tag="VQ865_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3134442.1"
                     /translation="MDKLVAAIEKQQGKFEKISTNNYMMAIKDGFIATMPLIMFSSFL
                     MIIIMIPKNFGVELPSPAIAWMRKVYMLTMGVLGIIVSGTVAKSLAGNVNRKMPPGKV
                     INDTSAMLAAICGYLVLTVTLVVDEKTGSTSLSTNYLGSQGLITSFVSAFITVNVYRF
                     CIKRDITIHLPKEVPGAISQAFRDIFPFSFVLLISGLLDIVSRFSLDVPFAQVFQQLL
                     TPIFKGAESYPAMMLIWFMCALLWFVGIHGPSIVLPAVTALQLSNMEENAQLLANGQF
                     PYHSLTPNFGNYIAAIGGTGATFVVPFILIFFMRSKQLKSVGKATITPVLFAVNEPLL
                     FGMPVILNPYLFVPFLMTPPVNVFLGKVFIDFFGMNGFYIQLPWAFPGPLGLLIGTNF
                     QLISFVFLSLMLVVDILIYLPFCRAYDRQLLVKEDIASSNDIILEEDTSEIMPCEIDV
                     IKSKELKVLVLCAGSGTSAQLANAINEGAQLAEVRVIANSGAYGAHYDIMGVYDLIIL
                     APQVRSYYREMKVDAERLGIQIVATRGMEYIHLTKSPSKALQFVLEHYQAV"
     gene            complement(6338..7750)
                     /gene="lacG"
                     /locus_tag="VQ865_000006"
     CDS             complement(6338..7750)
                     /gene="lacG"
                     /locus_tag="VQ865_000006"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3134443.1"
                     /translation="MENLQVKALPKEFLLGAATAAYQVEGATRVDGKGTNMWDVYLQE
                     NSPFLPDPASDFYYRYEEDIALAAEHGLQALRLSISWVRIFPDIDGEPNILAVRYYHR
                     VFQSCLKHNVIPFVSLHHFDSPQKMLETGDWLNRENIDRFIRYARFCFQEFTEVKHWF
                     TINELMSLAAGQYIGGQFPPNHHFQLSEAIQANHNMLLAHALAVREFHQLGIEGKIGC
                     IHALKPGYPIDGQKENILAAKRYDVYNNKFLLDGTFLGYYSEDTLFHLNQILEANNSS
                     FIIEDGDLEIMKRAAALNTMFGMNYYRSEFIREYKGENRQEFNSTGIKGQSSFKLNAL
                     GEFVKKPGIPTTDWDWNIYPQGLFDMLLRIKEEYPQHPVIYLTENGTALKEVKPEGEN
                     DIIDDSKRIRYIEQHLHKVLEARDRGVNIQGYFIWSLQDQFSWANGYNKRYGLFFVDY
                     ETQKRYIKKSALWVKGLKRN"
     gene            complement(7760..8104)
                     /locus_tag="VQ865_000007"
     CDS             complement(7760..8104)
                     /locus_tag="VQ865_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3134444.1"
                     /translation="MKSKEEINMLGFTIVAYAGDARSDLMDALAFARDGYFEQARELV
                     ESANDSIVSAHREQTNLLAEEASGDNFEVSFIMIHGQDTLMTTMLLYDQVKFFIDEYE
                     RIRKIEEHIGLQ"
     gene            complement(8272..10158)
                     /locus_tag="VQ865_000008"
     CDS             complement(8272..10158)
                     /locus_tag="VQ865_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000236922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4838 domain-containing protein"
                     /protein_id="HET3134445.1"
                     /translation="MVIRVFDQQKNTYSSFALEELSYYMNRVFKTNIELVEEKEADIF
                     VGLVNKEDRKDHVLISLDKGKGRIESNTIVGLLIGIYRMFHEFGVVYTRPGRRHDFVP
                     ELRFEDFLDKQLSIDETASYYHRGVCIEGADSFENILDFIDWLPKIGMNSFFIQFENP
                     YSFLKRWYEHEFNPYLNKEQFSNELVQELSDRLDKELQKRGLIHHRVGHGWTGEVLGY
                     SSKFGWESGLSISEEKKPYVAEINGKRELFNTAPILTSLDFSNPDVADKMVEIIKDYA
                     KKRPDVNYLHVWLSDARNNICECENCRQELVSDQYIRILNQLDRALTSEGLDTKICFL
                     LYHELLWAPQKEKLDNPERFTMMFAPITRTFEMSYADVDFDNSIPTPKPYLRNKIILP
                     NSLEENLSYLFEWQKTFKGDSFVYDYPLGRAHYGDLGYMKISQTIYRDVSYLSNLHLN
                     GYISCQELRAGFPHNFPNYVMGEMLWKKTRSYEELIEEYFSALYGSNWQSVVEYLEKL
                     SSYSSCDYFNAIGSRQNDVLANHYYIAYNLADNFLPIIEENISKLLNSQKDEWKQLSY
                     HREYVVKMAKALYLQATGKTRQAQDEWRNVLNYIRGHELLFQSNLDVYRVIEVAKNYA
                     GFHL"
     gene            complement(10160..11482)
                     /locus_tag="VQ865_000009"
     CDS             complement(10160..11482)
                     /locus_tag="VQ865_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3134446.1"
                     /translation="MNNILAFLETKVAPFGEKVGNQRHLKAIREGFMMAMPLILVGSL
                     FLILISWPQEDFTNWLNSVGLLSILTTMNQSTVAIISLVACFGIAYRLSEGYGTDGPS
                     AGIIALSSFVLMAPRFSSMVYDKNGEQVKQLFGGAIPFSSLNASSLFMAITIGLVTAE
                     IYRMFIQRGITIKMPSGVPDVVSKSFSALLPGFTTFVLWALVLKGLEAAGVAGGLNGL
                     LGGIVGTPLKLIAGTLPGMILCVIVNSFFWFCGVNGGQVLNAFVDPVWLQFTIENQEA
                     VAAGQTLQHIITLPFKDLFVFIGGGGATIGLAICLFLFSKSRANKTLGKLAIIPSIFN
                     INTAILFTFPTVLNPIMLIPFIATPTINALITYVSMAVGLVPYTTGVILPWTMPPIIG
                     GFLATGASWRGALLQVVLILVSVAIYYPFFKIADKRNLEKEKATVGGK"
     gene            11650..12873
                     /locus_tag="VQ865_000010"
     CDS             11650..12873
                     /locus_tag="VQ865_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3134447.1"
                     /translation="MITKQSAFLQNRATILEFLYRNPATSRTDIVNETGLTPATTTNI
                     IKELSEQSLIYETGDEFSEFSGSGRRRKTISITDNIPYVVGGIEINVLGIFLSLCDLQ
                     GKTLFETEILNEDYPISEINSTITNMIKTAIEYVPLETKLLGFGLSIPGHYNKDSGSI
                     ITNNPIWESFNLLNVIKRFNFPFIVKNNIDCMAIGQYLFNPHNTPDNFIFLHAGLGIY
                     TSFFTKEKIGASKNPYIGEIGHTIVELNGQYCECGKKGCLQTYISDAWLIKHAQLLFK
                     NSQLTVLKSLVKTEKDIHLDTLLTAYNLGDSALRQQIDKGVNLLATSIANLLLINPAD
                     KIYINSQLLNYQPFTHEVRDKIQDQLHFVPFTRNIEIEILPYNKHRGSIGACALAIVA
                     FFIEHSNVLQDIISP"
     gene            13696..13866
                     /locus_tag="VQ865_000011"
     CDS             13696..13866
                     /locus_tag="VQ865_000011"
                     /inference="COORDINATES: protein motif:HMM:NF024172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3134448.1"
                     /translation="MTKQVPKFTKDTAQLYTCKWLLYNKVTKMYDHTVVNHSVREYIT
                     DSISTNTIEEAG"
     gene            14478..14762
                     /locus_tag="VQ865_000012"
     CDS             14478..14762
                     /locus_tag="VQ865_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002923859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134449.1"
                     /translation="MDWYDYMIQASKQSQFNASHWFRYLRKVIFEDYSYLTNQDVEKL
                     LDSKELTRFQKISLKYAFQEHTPTHKYVISLNKPAKLTNVQKLMEKYKHG"
     gene            14755..14993
                     /locus_tag="VQ865_000013"
                     /pseudo
     CDS             14755..14993
                     /locus_tag="VQ865_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397100.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            15089..15307
                     /locus_tag="VQ865_000014"
     CDS             15089..15307
                     /locus_tag="VQ865_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134450.1"
                     /translation="MMSIREQDLQDIGAIIKYKNFHSPFDTFKYLKDMGFDTIDLSVL
                     LEGFSYAYGMDWLEKFFKENQDKLREFY"
     gene            complement(15679..18003)
                     /gene="pflB"
                     /locus_tag="VQ865_000015"
     CDS             complement(15679..18003)
                     /gene="pflB"
                     /locus_tag="VQ865_000015"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HET3134451.1"
                     /translation="MVVKTVVEAQDIFDKAWEGFKGVDWKEKASVSRFVQANYTPYDG
                     DESFLAGPTERSLHIKKIVEETKAHYEETRFPMDTRPTSIADIPAGFIDKENEVIFGI
                     QNDELFKLNFMPKGGIRMAETTLKENGYEPDPAVHEIFTKYVTTVNDGIFRAYTSNIR
                     RARHAHTVTGLPDAYSRGRIIGVYARLALYGADYLMQEKVNDWNAIKEIDEETIRLRE
                     EVNLQYQALQQVVRLGDLYGVDVRKPAMNVKEAIQWVNIAFMAVCRVINGAATSLGRV
                     PIVLDIFAERDLARGTFTESEIQEFVDDFVMKLRTVKFARTKAYDQLYSGDPTFITTS
                     MAGMGNDGRHRVTKMDYRFLNTLDNIGNSPEPNLTVLWTDKLPYNFRRYCMHMSHKHS
                     SIQYEGVTTMAKDGYGEMSCISCCVSPLDPENEEQRHNIQYFGARVNVLKALLTGLNG
                     GYDDVHKDYKVFDIDPIRDEVLEFESVKANFEKSLDWLTDTYVDALNIIHYMTDRYNY
                     EAVQMAFLPTKQRANMGFGICGFANTVDTLSAIKYATVKPIRDEDGYIYDYETIGDYP
                     RWGEDDPRSNELAEWLIEAYTTRLRSHKLYKDAEATVSLLTITSNVAYSKQTGNSPVH
                     KGVYLNEDGSVNLSKLEFFSPGANPSNKAKGGWLQNLNSLSSLDFSYAADGISLTTQV
                     SPRALGKTRDEQVDNLVTILDGYFENGGQHVNLNVMDLNDVYEKIMSGEDVIVRISGY
                     CVNTKYLTPEQKTELTQRVFHEVLSMDDALDALS"
     gene            18398..19459
                     /gene="dinB"
                     /locus_tag="VQ865_000016"
     CDS             18398..19459
                     /gene="dinB"
                     /locus_tag="VQ865_000016"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HET3134452.1"
                     /translation="MLIFPLLNDLSRKIIHIDMDAFFAAVEIKDNPKLRGKPVIIGSD
                     PRQTGGRGVVSTCSYEARAFGVHSAMSSKEAYERCPQAVFISGNYEKYKAVGLQIRAI
                     FKRYTDLIEPMSIDEAYLDVTENKLGIKSAVKIARLIQKDIWQELHLTASAGISYNKF
                     LAKMASDYQKPHGLTVILPEQAENFLKQMDISKFHGVGKKTVERLHQMGVFTGADLLE
                     VPEVTLIDRFGRLGYDLYRKARGIHNSPVKSNRIRKSIGKEKTYGKILRAEEDIKKEL
                     TLLSEKVALNLHQQEKAGKIVILKIRYEDFSTLTKRKSLAQKTQDASQISQIALQLYE
                     ELSEKERGVRLLGITLTGF"
     gene            complement(19606..20451)
                     /locus_tag="VQ865_000017"
     CDS             complement(19606..20451)
                     /locus_tag="VQ865_000017"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HET3134453.1"
                     /translation="MYLIEILKSIFFGIVEGITEWLPISSTGHLILAEEFIQYQNQNE
                     AFMSMFNVVIQLGAILAVMVIYFNKLNPFKPTKDKQEVRKTWRLWLKVLIATLPLLGV
                     FKFDDWFDTHFHNMVSVALMLIIYGVAFIYLEKRNKARAIEPSVTELDKLPYTTAFYI
                     GLFQVLALLPGTSRSGATIVGGLLNGTSRSVVTEFTFYLGIPVMFGASALKIFKFVKA
                     GELLSFGQLFLLLVAMGVAFAVSMVAIRFLTSYVKKHDFTLFGKYRIVLGSVLLLYSF
                     VRLFV"
     gene            20707..21575
                     /locus_tag="VQ865_000018"
                     /pseudo
     CDS             20707..21575
                     /locus_tag="VQ865_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841243.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(21876..23765)
                     /locus_tag="VQ865_000019"
     CDS             complement(21876..23765)
                     /locus_tag="VQ865_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HET3134454.1"
                     /translation="MKKTFFLLVLGLFCLLPLSVFAIDFKINSYQGDLYIHADNTAEF
                     RQKIVYQFEEDFKGQIVGLGRAGKMPSGFDIDPHPKIQAAKNGAELADVTSEVTEEAD
                     GYTVRVYNPGQEGDIVEVDLVWNLKNLLFLYDDIAELNWQPLTDSSESIEKFEFHVRG
                     DKGAEKLFFHTGKLFRERTVEKSNLDYTIRLDNLPAKRGVELHAYWPRTDFASARDQG
                     LKGNRLEEFNKIEDSIVKEKDQSKQLLTWIFPSILSISLLLSICFYFIYRRKTAPSIK
                     YAKNHRLYEPPMELEPMVLSEAVYSTSLEEVSPLVKGAGKFTFDQLIQATLLDVIDRG
                     NVSIISEGDAVGLRLVKEDGLSSFEKDCLNLAFSGKKEETLSNLFADYKVSDSLYRRA
                     KVSDEKRIQARGLQLKSSFEEVLNQMQEGVRKRVSFWGLPDYYRPLTGLEKALQVGMG
                     VLTILPLFIGFGLFLYSLDVHGYLYLPLPILGFLGLVLSVFYYWKLRLDNRDGVLNEA
                     GAEVYYLWTSFENMLREIARLDKAELESIVVWNRLLVYATLFGYADKVSHLMKVHQIQ
                     VENPDINLYVAYGWHSMFYHSSAQMSHYASVANTASTYSVSSGSGSSGGGFSGGGGGG
                     SIGAF"
     gene            23903..25468
                     /locus_tag="VQ865_000020"
     CDS             23903..25468
                     /locus_tag="VQ865_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3134455.1"
                     /translation="MRKIYLSIFTSLLLMLGLVNVAQADEYLRIGMEAAYAPFNWTQD
                     DDSNGAVKIDGTNQYANGYDVQIAKKIAKDLGKEPLVVKTKWEGLVPALTSGKIDMII
                     AGMSPTAERKQEITFSSSYYTSEPVLLVKKDSAYASAKSLDDFNGAKITSQQGVYLYN
                     LIAQIPGAKKETAMGDFAQMRQALEAGVIDAYVSERPEALTAEAANSKFKMIQVEPGF
                     KTGEEDTAIAIGLRKNDNRISQINASIETISKDDQVALMDRMIKEQPAEATTTEETSS
                     SFFSQVAKILSENWQQLLRGAGITLLISIVGTIIGLIIGLAIGVFRTAPLSENKVIYG
                     LQKLVGWVLNVYIEIFRGTPMIVQSMVIYYGTAQAFGINLDRTLAAIFIVSINTGAYM
                     TEIVRGGILAVDKGQFEAATALGMTHNQTMRKIVLPQVVRNILPATGNEFVINIKDTS
                     VLNVISVVELYFSGNTVATQTYQYFQTFTIIAVIYFVLTFTVTRILRFIERRMDMDTY
                     TTGANQMQTEDLK"
     gene            25468..26208
                     /locus_tag="VQ865_000021"
     CDS             25468..26208
                     /locus_tag="VQ865_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3134456.1"
                     /translation="MTQAILEIKHLKKSYGQNEVLKDISLTVHKGEVISIIGSSGSGK
                     STFLRSINLLETPTDGQILYHGQNVLEKGYDLTQYREKLGMVFQSFNLFENLNVLENT
                     IVAQTTVLKRERTEAEKIAKENLEKVGMGERYWQAKPKQLSGGQKQRVAIARALSMNP
                     DAILFDEPTSALDPEMVGEVLKIMQDLAQEGLTMIVVTHEMEFARDVSHRVIFMDKGV
                     IAEEGKPEDLFTNPKEDRTKEFLQRYLK"
     gene            complement(26317..26532)
                     /locus_tag="VQ865_000022"
     CDS             complement(26317..26532)
                     /locus_tag="VQ865_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134457.1"
                     /translation="MAKSNFEKVESVVGWVRDKKITGYRISKETNAREMSIIALAQGR
                     AKVKNISFETALGLIDFYEKNYEKFED"
     gene            complement(27403..28653)
                     /gene="ilvA"
                     /locus_tag="VQ865_000023"
     CDS             complement(27403..28653)
                     /gene="ilvA"
                     /locus_tag="VQ865_000023"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase IlvA"
                     /protein_id="HET3134458.1"
                     /translation="MLSSKDIIKAHKVLNGVVVNTPLDYDHYLSEKYGAKIYLKKENA
                     QRVRSFKIRGAYYAISQLSKEERERGVVCASAGNHAQGVAYTCNEMKIPATIFMPITT
                     PQQKIGQVRFFGGDFVTIKLVGDTFDASAKAAQEFTVSENRTFIDPFDDAHVQAGQGT
                     VAYEILEEARKESIDFDAVLVPVGGGGLIAGVSTYIKETSPEIEVIGVEANGARSMKA
                     AFEAGGPVKLKEIDKFADGIAVQKVGQLTYEATRQHIKTLVGVDEGLISETLIDLYSK
                     QGIVAEPAGAASIASLEVLAEYIKGKTICCIISGGNNDINRMPEMEERALIYDGIKHY
                     FVVNFPQRPGALREFVNDILGPNDDITRFEYIKRASKGTGPVLIGIALADKHDYAGLI
                     RRMEGFDPAYINLNGNETLYNMLV"
     gene            complement(28703..29059)
                     /locus_tag="VQ865_000024"
     CDS             complement(28703..29059)
                     /locus_tag="VQ865_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3134459.1"
                     /translation="MNITNLFSIKTGCDETDRQLQKLFFQLDLQLGELTDQLRKLDSN
                     FVPRSQFVDTLDLNDVEYKEILNYFIFHRNDSEESLVEWLYDWISTNRYELPKEFSIR
                     MAHKYHESVTEVFGDE"
     gene            complement(29297..29533)
                     /locus_tag="VQ865_000025"
     CDS             complement(29297..29533)
                     /locus_tag="VQ865_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134460.1"
                     /translation="MLADQNKADWSYDENAVINIYDDANFEDGRLHMTFEQFFKLAQI
                     AREEGLEIHSPFERADATKSARYIAKWILRNKKH"
     gene            complement(29640..30662)
                     /gene="ilvC"
                     /locus_tag="VQ865_000026"
     CDS             complement(29640..30662)
                     /gene="ilvC"
                     /locus_tag="VQ865_000026"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HET3134461.1"
                     /translation="MTVQMEYEKDVKVAALDGKKIAVIGYGSQGHAHAQNLRDSGRDV
                     IIGVRPGKSFDKAKEDGFDTYTVAEATKLADVIMILAPDEIQQELYEAEIAPNLEAGN
                     AVGFAHGFNIHFEFIKVPADVDVFMCAPKGPGHLVRRTYEEGFGVPALYAVYQDATGN
                     AKNIAMDWCKGVGAARVGLLETTYKEETEEDLFGEQAVLCGGLTALIEAGFEVLTEAG
                     YAPELAYFEVLHEMKLIVDLIYEGGFKKMRQSISNTAEYGDYVSGPRVITEQVKENMK
                     AVLADIQNGKFANDFVNDYKAGRPKLTAYREQAANLEIEKVGAELRKAMPFVGKNDDD
                     AFKIYN"
     gene            complement(30728..31204)
                     /gene="ilvN"
                     /locus_tag="VQ865_000027"
     CDS             complement(30728..31204)
                     /gene="ilvN"
                     /locus_tag="VQ865_000027"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002927678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HET3134462.1"
                     /translation="MRRMLTAKLQNRSGVLNRFTGVLSRRQVNIESISVGATEDPNVS
                     RITIIIDVASHDEVEQIIKQLNRQIDVIRIRDITDKPHLEREVILVKMSAPAEKRAEI
                     LAIIQPFRATVVDVAPSSITIQMTGNAEKSEALLRVIRPYGIRNIARTGATGFTRD"
     gene            complement(31197..32897)
                     /locus_tag="VQ865_000028"
     CDS             complement(31197..32897)
                     /locus_tag="VQ865_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HET3134463.1"
                     /translation="MEKISLESPKTGSDLVLETLRDLGVDTIFGYPGGAVLPFYDAIY
                     NFKGIRHILGRHEQGCLHEAEGYAKSTGKLGVAVVTSGPGATNAITGIADAMSDSVPL
                     LVFTGQVARAGIGKDAFQEADIVGITMPITKYNYQVRETADIPRIITEAVHIATTGRP
                     GPVVIDLPKDISALETDFIYSPEVNLPSYQPTLEPNDMQIKKILKQLSKAKKPVLLAG
                     GGISYAEAATELNEFAERYQIPVVTSLLGQGTIATSHPLFLGMGGMHGSFAANIAMTE
                     ADFMISIGSRFDDRLTGNPKTFAKNAKVAHIDIDPAEIGKIISADIPVVGDAKKALQM
                     LLAEPTVHNNTEKWIEKVTKDKNRVRSYDKKERVVQPQAVIERIGELTNGDAIVVTDV
                     GQHQMWTAQYYPYQNERQLVTSGGLGTMGFGIPAAIGAKIANPDKEVVLFVGDGGFQM
                     TNQELAILNIYKVPIKVVMLNNHSLGMVRQWQESFYEGRTSESVFDTLPDFQLMAQAY
                     GIKNYKFDNPETLAQDLEVITEDVPMLIEVDISRKEQVLPMVPAGKSNHEMLGVKFHA
                     "
     gene            complement(33098..34765)
                     /locus_tag="VQ865_000029"
     CDS             complement(33098..34765)
                     /locus_tag="VQ865_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HET3134464.1"
                     /translation="MSKITTSLFQEMVQAASTRLNKQAEYVNSLNVFPVPDGDTGTNM
                     GMTIENGAKEVADKPASTVGEVASILAKGLLMGARGNSGVITSQLFRGFSQAIKDKDE
                     LTGQDLALAFQSGVEVAYKAVMKPVEGTILTVSRGAAIGAKKKAEQTDDAVEVMRAAL
                     EGAKTALAKTPDMLPVLKEVGVVDSGGQGLVFIYEGFLSALTGEYIASEDFVATPANM
                     SEMINVEHHKSVAGHVATEDITFGYCTEIMVALKQGPTYAKDFDYDEFRNYLDELGDS
                     LLVVNDDEIVKVHVHTEDPGLVMQEGLKYGSLVKVKVDNMRNQHEAQVEKEATQVIKS
                     AEEKEYALIAVVAGKGLADIFCSQGVDYVIEGGQTMNPSTEDFIKAVEQVNARNIIFL
                     PNNKNIFMAAQSAAEVLEQPAVVVEARTLPQGMTSLLAFDPSKSIEENQERMTAALSD
                     VVSGSVTTAVRDTTIDGLEIHENDNLGMVDGKILVSNPDMHQTLTETLKHMLDEDSEI
                     VTFYVGEDGSEELANEIAQEIVEEFEDVEVEIHQGQQPVYPYLFSVE"
     gene            complement(34768..35133)
                     /locus_tag="VQ865_000030"
     CDS             complement(34768..35133)
                     /locus_tag="VQ865_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3134465.1"
                     /translation="MTVKINTKDGQIELTDEVIATVVGGAATEIFGVVGMASKNALKD
                     NFQALLGKENYSKGVVVKAAEDGSIAVDVYTVLSYGTKISEVSKNIQERVAFSLENQL
                     GITAQTVNVYIQNIKVVGE"
     gene            complement(35290..35478)
                     /locus_tag="VQ865_000031"
     CDS             complement(35290..35478)
                     /locus_tag="VQ865_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008536053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HET3134466.1"
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNQTKRAVKPNLQKVTVLIDGKP
                     KKVWASARALKSGKVERV"
     gene            complement(35597..36079)
                     /locus_tag="VQ865_000032"
                     /pseudo
     CDS             complement(35597..36079)
                     /locus_tag="VQ865_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204109.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
     gene            complement(36348..37892)
                     /locus_tag="VQ865_000033"
     CDS             complement(36348..37892)
                     /locus_tag="VQ865_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HET3134467.1"
                     /translation="MNIQEEIKKRRTFAIISHPDAGKTTITEQLLYFGGEIRDAGTVK
                     GKKTGTFAKSDWMDIEKQRGISVTSSVMQFDYDGKRVNILDTPGHEDFSEDTYRTLMA
                     VDAAVMVVDSAKGIEAQTKKLFEVVKHRGIPVFTFMNKLDRDGREPLDLLQELEEILG
                     IASYPMNWPIGMGKAFEGLYDLYNQRLELYKGDERFASLEDGDKLFGSNPFYEQVKDD
                     IELLNEAGNEFSEEAILAGELTPVFFGSALTNFGVQTFLEIFLKFAPEPHGHKKTDGE
                     IVDPYDKDFSGFVFKIQANMDPRHRDRIAFVRIVSGEFERGMSVNLPRTGKGAKLSNV
                     TQFMAESRENVTNAVAGDIIGVYDTGTYQVGDTLTVGKNKFEFEPLPTFTPEIFMKVS
                     AKNVMKQKSFHKGIEQLVQEGAVQLYKNYQTGEYMLGAVGQLQFEVFKHRMESEYNAE
                     VVMNPMGKKTVRWIKPEDLDERMSSSRNILAKDRFDQPVFLFENDFALRWFADKYPDV
                     ELEEKM"
     gene            38105..38407
                     /gene="gatC"
                     /locus_tag="VQ865_000034"
     CDS             38105..38407
                     /gene="gatC"
                     /locus_tag="VQ865_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HET3134468.1"
                     /translation="MKITQEEVTHVANLSKLRFSEKETAAFATTLSKIVDMVELLGEV
                     DTTGVAPTTTMADRKTVLRPDVAEEGTDRDRLFKNVPEQDNYYIKVPAILDDGGDA"
     gene            38407..39873
                     /gene="gatA"
                     /locus_tag="VQ865_000035"
     CDS             38407..39873
                     /gene="gatA"
                     /locus_tag="VQ865_000035"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HET3134469.1"
                     /translation="MTFNNKTIEELHNLLVSKEISATELTQATLENIKSREEALNSFV
                     TIAEEQALVQAKAIDEAGIDADNVLSGIPLAVKDNISTDGILTTAASKMLYNYEPIFD
                     ATAVANAKTKGMIVVGKTNMDEFAMGGSGETSHYGATKNAWDHSKVPGGSSSGSAAAV
                     ASGQVRLSLGSDTGGSIRQPAAFNGIVGLKPTYGTVSRFGLIAFGSSLDQIGPFAPTV
                     KENALLLNAIASEDAKDSTSAPVRIADFTSKIGQDIKGMKIALPKEYLGEGINPEVKE
                     TILNAAKHFEKLGAIVEEVSLPHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRAEDA
                     TNLDEIYVNSRSQGFGEEVKRRIMLGTFSLSSGYYDAYYKKAGQVRTLIIQDFEKVFA
                     DYDLILGPTAPSVAYDLDSLNHDPVAMYLADLLTIPVNLAGLPGISIPAGFSQGLPVG
                     LQLIGPKYSEETIYQAAAAFEATTDYHKQQPVIFGGDN"
     gene            39873..41315
                     /gene="gatB"
                     /locus_tag="VQ865_000036"
     CDS             39873..41315
                     /gene="gatB"
                     /locus_tag="VQ865_000036"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HET3134470.1"
                     /translation="MNFETVIGLEVHVELNTNSKIFSPTSAHFGNDQNANTNVIDWSF
                     PGVLPVLNKGVVDAGIKAALALNMDIHKKMHFDRKNYFYPDNPKAYQISQFDEPIGYN
                     GWIEVKLEDGTTKKIGIERAHLEEDAGKNTHGTDGYSYVDLNRQGVPLIEIVSEADMR
                     SPEEAYAYLTALKEVIQYAGISDVKMEEGSMRVDANISLRPYGQEKFGTKTELKNLNS
                     FSNVRKGLEYEIQRQAEILRSGGQIRQETRRYDEANKTTILMRVKEGAADYRYFPEPD
                     LPLFEISDEWIEEMRTELPEFPKERRARYVSDLGLSDYDANQLTANKVTSDFFEKAVA
                     LGGDAKQVSNWLQGEVAQFLNAEGKTLEQIELTPENLVEMITIIEDGTISSKIAKKVF
                     VHLAKNGGGAREYVEKAGMVQISDPAILIPIIHQVFADNEAAVADFKSGKRNADKAFT
                     GFLMKATKGQANPQVALKLLAQELAKLKEN"
     gene            41439..42482
                     /locus_tag="VQ865_000037"
     CDS             41439..42482
                     /locus_tag="VQ865_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-butanediol dehydrogenase"
                     /protein_id="HET3134471.1"
                     /translation="MATMKAARWHAAKDVRIQEIEVPEVLPHQVKVAVKFTGICGTDL
                     HEFLDGPIFIPTDEHVYSGQKAPVTLGHEFSGEIIEVGSDVTRVKVGDRVAVEPILAK
                     NNLVGDYNLDPNLNFVGLAADGGFAKYCVLDGDLVHVIPDSLSYEQAALTEPAAVAVY
                     AVRQSSLKAGDTAVVFGLGPIGLLIVEALRAAGASKIYAVELSPERQAKAEELGAIVV
                     RPEEGETAVEAIHRLTNGGVDVSYEVTGVPVVLGQALAAVHKAGECMVVSIWEREANI
                     NPNEFAIQEKTLKGIIAYRHIFPKVLELMEQGYFSAEKLVTKKIKLENIVEEGFIELT
                     QDKSQIKILVEPE"
     gene            42860..43420
                     /gene="efp"
                     /locus_tag="VQ865_000038"
     CDS             42860..43420
                     /gene="efp"
                     /locus_tag="VQ865_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HET3134472.1"
                     /translation="MIEASKLKAGMTFETADGKLIRVLEASHHKPGKGNTIMRMKLRD
                     VRTGSTFDTSYRPEEKFEQAIIETVPAQYLYKMDDTAYFMNTETYDQYEIPVVNVENE
                     LLYILENSDVKIQFYGTEVIGVTVPTTVELTVAETQPSIKGATVTGSGKPATMETGLV
                     VNVPDFIEAGQKLVINTAEGTYVSRA"
     gene            43442..43831
                     /locus_tag="VQ865_000039"
     CDS             43442..43831
                     /locus_tag="VQ865_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3134473.1"
                     /translation="MGIEEQLGEIVIAPRVLEKIIAIATAKVEGVHSFSNRSVSDTLS
                     KLSLGRGIYLKNVDEELTADIYLYLEYGVKVPKVAVAIQKAVKDAVRNMADVELAAIN
                     IHVAGIVPDKTPKPELKDLFDEDFLND"
     gene            43824..44246
                     /gene="nusB"
                     /locus_tag="VQ865_000040"
     CDS             43824..44246
                     /gene="nusB"
                     /locus_tag="VQ865_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000203663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HET3134474.1"
                     /translation="MTSPLLESRRQLRKCAFQALMSLEFGTDVETACRFAYTHDREDT
                     DVQLPAFLIDLVSGVQAKKEELDKQITQHLKAGWTIERLTLVERNLLRLGVFEITSFD
                     TPQLVAVNEAIELAKDFSDQKSARFINGLLSQFVTEEQ"
     gene            complement(44296..44532)
                     /locus_tag="VQ865_000041"
     CDS             complement(44296..44532)
                     /locus_tag="VQ865_000041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3134475.1"
                     /translation="MDVILSAIIFGISHLILSHRDPISLLYYSLIGFFFALVYRSTDN
                     LRLTILCHSFFNFLNHAKPIWIFVYNYIYYHFFR"
     gene            complement(44545..45018)
                     /locus_tag="VQ865_000042"
     CDS             complement(44545..45018)
                     /locus_tag="VQ865_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134476.1"
                     /translation="MRNTKKLRQFGIFLLIILLSTYLPQTIGLYVTIILGLGADVYSL
                     ILTMGLVGSFLLLIWRLKKKKMLFIFEKKSWNWSFVFYLFATYVVYQILGNFWARYAH
                     LINHRNIHDEYFTVLFSNGQPTFLSTILSFVLPVIIGPVFEETLDRGYFMNTFFP"
     gene            complement(45036..45221)
                     /gene="briC"
                     /locus_tag="VQ865_000043"
     CDS             complement(45036..45221)
                     /gene="briC"
                     /locus_tag="VQ865_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-regulating peptide BriC"
                     /protein_id="HET3134477.1"
                     /translation="MTGTNTFTVLSTEDLEQTSGGLAVWEDGYSRWLYYREFAPYMRQ
                     GALNSYIDAWKYGFRAG"
     gene            complement(45380..46147)
                     /locus_tag="VQ865_000044"
     CDS             complement(45380..46147)
                     /locus_tag="VQ865_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HET3134478.1"
                     /translation="MNIAKIVREAREQSRLTTLDFATGIFDEFIQLHGDRSFRDDGAV
                     VGGIGWLGDQAVTVVGIQKGKSLQDNLKRNFGQPHPEGYRKALRLMKQAEKFGRPVVT
                     FINTAGAYPGVGAEERGQGEAIARNLMEMSDLKVPIIAIIIGEGGSGGALALAVADRV
                     WMLENSIYAILSPEGFASILWKDGTRAMEAAELMKITSHELLEMDVVDKVISEIGLSS
                     KELIKSVKKELQTELARLSQKPLEELLEERYQRFRKY"
     gene            complement(46144..47010)
                     /locus_tag="VQ865_000045"
     CDS             complement(46144..47010)
                     /locus_tag="VQ865_000045"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001173351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HET3134479.1"
                     /translation="MALFSKKDKYIRINPNRSVREKPQAKPEVPDELFSQCPGCKHTI
                     YQKDLGSERICPHCSYTFRISAQERLALTIDMGTFKELFTGIESKDPLHFPGYQKKLA
                     SMREKTGLHEAVVTGTALIKGQTVALGIMDSNFIMASMGTVVGEKITRLFEYATVEKL
                     PVVLFTASGGARMQEGIMSLMQMAKISAAVKRHSNVGLFYLTILTDPTTGGVTASFAM
                     EGDIILAEPQSLVGFAGRRVIENTVRESLPEDFQKAEFLLEHGFVDAIVKRRDLPDTI
                     ASLVRLHGGSPR"
     gene            complement(47047..48414)
                     /gene="accC"
                     /locus_tag="VQ865_000046"
     CDS             complement(47047..48414)
                     /gene="accC"
                     /locus_tag="VQ865_000046"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000488661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HET3134480.1"
                     /translation="MFRKILIANRGEIAVRIIRAARELGIATVAVYSTADKEALHTLL
                     ADEAVCIGPGKATESYLNINAVLSAAVLTEAEAIHPGFGFLSENSKFATMCEEVGIKF
                     IGPSGHVMDMMGDKINARAQMIKAGVPVIPGSDGEVHNSEEALIVAEKIGYPVMLKAS
                     AGGGGKGIRKVEKPDDLVSAFETASSEAKANYGNGAMYIERVIYPARHIEVQILGDEH
                     GHVIHLGERDCSLQRNNQKVLEESPSIAIGKTLRHEIGAAAVRAAEFVGYENAGTIEF
                     LLDEASSNFYFMEMNTRVQVEHPVTEFVSGVDIVKEQICIAAGQPLSVKQEDIVLRGH
                     AIECRINAENPAFNFAPSPGKITNLYLPSGGVGLRVDSAVYPGYTIPPYYDSMIAKII
                     VHGENRFDALMKMQRALYELEIEGVQTNADFQLDLISDRNVIAGDYDTSFLMETFLPK
                     YQEKE"
     gene            complement(48426..48848)
                     /gene="fabZ"
                     /locus_tag="VQ865_000047"
     CDS             complement(48426..48848)
                     /gene="fabZ"
                     /locus_tag="VQ865_000047"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HET3134481.1"
                     /translation="MIDIQGIKEALPHRYPMLLVDRVLEVSEDTIVAIKNVTINEPFF
                     NGHFPQYPVMPGVLIMEALAQTAGVLELSKPENKGKLVFYAGMDKVKFKKQVVPGDQL
                     VMTATFVKRRGTIAVVEAKAEVDGKLAASGILTFAIGN"
     gene            complement(48845..49330)
                     /locus_tag="VQ865_000048"
     CDS             complement(48845..49330)
                     /locus_tag="VQ865_000048"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HET3134482.1"
                     /translation="MNLNDIKDLMTQFDQSSLREFSYKNGTDELQFSKNEARPVPEVA
                     TQVAPAPVLATPNPVAPTSAPAETVAEEVPAPAEASVASEGNLVESPLVGVVYLAAGP
                     DKPAFVTVGDSVKKGQTLVIIEAMKVMNEIPAPKDGVVTEILVSNEEMVEFGKGLVRI
                     K"
     gene            complement(49333..50568)
                     /gene="fabF"
                     /locus_tag="VQ865_000049"
     CDS             complement(49333..50568)
                     /gene="fabF"
                     /locus_tag="VQ865_000049"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000774039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HET3134483.1"
                     /translation="MKLNRVVVTGYGVTSPIGNTPEEFWNSLATGKIGIGGITKFDHS
                     DFDVHNAAEIQDFPFDKYFVKKDTNRFDNYSLYALYAAQEAVNHANLDVEALNRDRFG
                     VIVASGIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMRFGANGVCKSI
                     NTACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRA
                     SIPFDKDRNGFVMGEGSGMLVLESLEHAEKRGATILAEVVGYGNTCDAYHMTSPHPEG
                     QGAIKAIKLALEEAEISPEQVAYVNAHGTSTPANEKGESGAIVAVLGKEVPVSSTKSF
                     TGHLLGAAGAVEAIVTIEAMRHNFVPMTAGTSEVSDYIEANVVYGQGLEKEIPYAISN
                     TFGFGGHNAVLAFKRWENR"
     gene            complement(50590..51321)
                     /gene="fabG"
                     /locus_tag="VQ865_000050"
     CDS             complement(50590..51321)
                     /gene="fabG"
                     /locus_tag="VQ865_000050"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HET3134484.1"
                     /translation="MKLEHKNIFITGSSRGIGLAIAHKFAQAGANIVLNSRGAISEEL
                     LAEFSNYGIKVVPISGDVSDFADAKRMIDQAIAELGSVDVLVNNAGITQDTLMLKMTE
                     ADFEKVLKVNLTGAFNMTQSVLKPMMKAREGAIINMSSVVGLMGNIGQANYAASKAGL
                     IGFTKSVAREVASRNIRVNVIAPGMIESDMTAILSDKIKEATLAQIPMKEFGQAEQVA
                     DLTVFLAGQDYLTGQVVAIDGGLSM"
     gene            complement(51355..52275)
                     /gene="fabD"
                     /locus_tag="VQ865_000051"
     CDS             complement(51355..52275)
                     /gene="fabD"
                     /locus_tag="VQ865_000051"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HET3134485.1"
                     /translation="MTKTAFLFAGQGAQYLGMGRDFYDQYPIVKETIDRASQVLGYDL
                     RYLIDTEEDKLNQTRYTQPAILATSVAIYRLLQEKGYQPDMVAGLSLGEYSALVASGA
                     LDFEDAVALVAKRGAYMEEAAPADSGKMVAVLNTPVEVIEEACQKASELGVVTPANYN
                     TPAQIVIAGEVVAVDRAVELLQEAGAKRLIPLKVSGPFHTALLEPASQKLAETLAQVS
                     FSDFTCPLVGNTEAAVMQKEDIAQLLTRQVKEPVRFYESIGVMQEAGISNFIEIGPGK
                     VLSGFVKKIDQTAHLAHVEDQASLVALLEK"
     gene            complement(52268..53242)
                     /gene="fabK"
                     /locus_tag="VQ865_000052"
     CDS             complement(52268..53242)
                     /gene="fabK"
                     /locus_tag="VQ865_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-[acyl-carrier-protein] reductase FabK"
                     /protein_id="HET3134486.1"
                     /translation="MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGG
                     NAPKEVVKANIDKIKSLTDKPFGVNIMLLSPFVEDIVDLVIEEGVKVVTTGAGNPSKY
                     MERFHEAGIIVIPVVPSVALAKRMEKIGADAVIAEGMEAGGHIGKLTTMTLVRQVATA
                     ISIPVIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKESNAHPNYKEKILKARDIDT
                     TISAQHFGHAVRAIKNQLTRDFELAEKDAFKQEDPDLEIFEQMGAGALAKAVVHGDVD
                     GGSVMAGQIAGLVSKEETAEEILKDLYYGAAKKIQEEASRWAGVVRND"
     gene            complement(53361..53585)
                     /locus_tag="VQ865_000053"
     CDS             complement(53361..53585)
                     /locus_tag="VQ865_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3134487.1"
                     /translation="MAVFEKVQEIIVEELGKDASEVTLESTFDDLDADSLDLFQVISE
                     IEDAFDIQIEAENDLKTVGDLVAYVEEQAK"
     gene            complement(53645..54619)
                     /locus_tag="VQ865_000054"
     CDS             complement(53645..54619)
                     /locus_tag="VQ865_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HET3134488.1"
                     /translation="MAFAKISQVAHYVPEQVVTNHDLAQIMDTNDEWISSRTGIRQRH
                     ISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITPDSMMPSTAARVQANIGANK
                     AFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDRSTAVLFGDG
                     AGGVLLEASEQEHFLAESLNSDGSRSECLTYGHSGLHSPFSDQESADSFLKMDGRTVF
                     DFAIRDVAKSIKQTIDESPIEVTDLDYLLLHQANDRILDKMARKIGVDRAKLPANMME
                     YGNTSAASIPILLSECVEQGLIPLDGSQTVLLSGFGGGLTWGTLILTI"
     gene            complement(54619..55053)
                     /locus_tag="VQ865_000055"
     CDS             complement(54619..55053)
                     /locus_tag="VQ865_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3134489.1"
                     /translation="MDYQRINEYLTSIFNNVLVIEEVNLRGSRFKDISIKEMHTIDVI
                     GKAPDVTPSQVSKELMVTLGTVTTSLNNLERKGYIERVRSEQDRRVVHLHLTKKGRLI
                     HRLHKRFHKAMVEKIIDGMSEEEIAVMGKGLTNLYQFLEDLK"
     gene            complement(55147..55932)
                     /locus_tag="VQ865_000056"
     CDS             complement(55147..55932)
                     /locus_tag="VQ865_000056"
                     /EC_number="4.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase"
                     /protein_id="HET3134490.1"
                     /translation="MEHIIYQLEEDLAILTLNRPEVANGFHIPMCEEILEALTLAEEN
                     PAVHFILINANGKVFSVGGDLVEMKRAVDEDDIPSLTKIAELVNTISYKIKQIAKPVL
                     MEVDGAVAGAAANMAVAADFCLATDKAKFIQAFVGVGLAPDAGGIHLLSRSIGVTRAA
                     QLAMTGEALTAEKALEWGLVYRVSEAEKLEKTREQLLKKLRRASSNSYAAIKKLVWES
                     QFKDWQGYATLELNLQKSLAQTEDFKEGVRAHSERRRPKFTGK"
     gene            56257..57621
                     /locus_tag="VQ865_000057"
     CDS             56257..57621
                     /locus_tag="VQ865_000057"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HET3134491.1"
                     /translation="MKVVKFGGSSLASASQLEKVLNIVKSDSERRFVVVSAPGKRNAE
                     DTKVTDALIKYYRDYVAGNDISKSQSWIIDRYAAMVSELGLKPAVLEKISKSIHALAT
                     LPIEENEFLYDTFLAAGENNNAKLIAAYFNQNGIDARYMHPREAGIVVTSEPGHARII
                     PSSYDKIEELTNTNEVLVIPGFFGVTKENQICTFSRGGSDITGSIIAAGVKADLYENF
                     TDVDGIFAAHPGIIHQPHSIPELTYREMRELAYAGFSVLHDEALLPAYRGKIPLVIKN
                     TNNPDHPGTRIVLKHSNDEFPVVGIAGDSGFVSINMSKYLMNREVGFGRKVLQILEEL
                     NIGWEHMPTGIDDLSIILRSRQLTPIKEEEILRQLVQKAKVDHAEIEHDLSIIMIVGE
                     KMKSHIGVTATATRALSENKINIQMMSQGSSEVSIMFVVNKDQEKAAIKALYNAFFGE
                     SKED"
     gene            57624..57995
                     /locus_tag="VQ865_000058"
     CDS             57624..57995
                     /locus_tag="VQ865_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HET3134492.1"
                     /translation="MAQSLNKTVLLSTTGTSYLSIAGKVGKFLVGDQALEFYPDVNVE
                     QFIQIPWSHINQIGANVTGCKISRHFEVFTDKGKFLFASKDSGAILKIARDKLGNDKV
                     VKLPTLIQTISQKFKNLFAKK"
     gene            58209..59483
                     /gene="serS"
                     /locus_tag="VQ865_000059"
     CDS             58209..59483
                     /gene="serS"
                     /locus_tag="VQ865_000059"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000884256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HET3134493.1"
                     /translation="MLDIKRIRTDFEAVAEKLATRGVDAAVLNEMKEIDAKRRNILVK
                     VETLKAERNTVSAEIAQAKRNKENTDDKIAAMQNLSAEVKALDAELAEIDAKLTEFTT
                     TLPNIPADSVPVGADEDDNVEVRRWGTPREFDFEPKAHWDLGEDLGILDWERGGKVTG
                     ARFLFYKGLGARLERAIYNFMLDEHGKEGYTEVITPYIVNHDSMFGTGQYPKFKEDTF
                     ELSDTNFVLIPTAEVPLANYYRDEILDGKDLPIYFTAMSPSFRSEAGSAGRDTRGLIR
                     LHQFHKVEMVKFAKPEESYEELEKMTANAENILQKLNLPYRVVALSTGDMGFSAAKTY
                     DLEVWIPAQNNYREISSCSNTEDFQARRAQIRYRDEADGKVKLLHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTIPEALRPYMGGAEVIKP"
     gene            complement(59508..60407)
                     /locus_tag="VQ865_000060"
     CDS             complement(59508..60407)
                     /locus_tag="VQ865_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000735961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HET3134494.1"
                     /translation="MKKLPLVFSGCLLGLAGAGNLILDTLPVLSHLFSLTGLVLWIYF
                     LILHLFNWKETKQELTKPPLLSGMATFPMAGMILSTYVFRVFSYLPLVAQGIWWFSFL
                     LDLTLIAGFTIKFACSGRRVHATPSWTVLYVGIAVAALTYPLVGIIEIAYATLSFGFL
                     LTFYLYPLIYSDLKKHPLPLALLGQEGIYCAPFSLLLASLVRVGGTSLPNWVLIVMIL
                     ASQSFFFFVLTRLPNILKQGFQPAFSALTFPTIITATSLKMAQGILKLPFLDYLVLAE
                     TIICLTILFFVLGAYLIWLRKKV"
     gene            complement(60517..61065)
                     /locus_tag="VQ865_000061"
     CDS             complement(60517..61065)
                     /locus_tag="VQ865_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000206764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HET3134495.1"
                     /translation="MTTFTIHTVESAPAEVKEILETVEKDNNGYIPNLIGLLANAPTV
                     LEAYQIVSSIHRRNSLTPVEREVVQITAAVTNGCAFCVAGHTAFSIKQIQMNDDLIQA
                     LRNRTPIETDPKLDTLAKFTLAVINTKGRVGDEALSEFLEAGYTQQNALDVVFGVSLA
                     ILCNYANNLANTPINPELQPYA"
     gene            complement(61283..62605)
                     /locus_tag="VQ865_000062"
     CDS             complement(61283..62605)
                     /locus_tag="VQ865_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HET3134496.1"
                     /translation="MLELLKSIDDFAWGPPLLILLVGTGIYLTMRLGLLQVLRLPKAF
                     QLIFIQDKGHGDVSSFAALCTALASTVGTGNIIGVATAIKVGGPGALFWMWMAAFFGM
                     ATKYAEGLLAIKYRTKDDHGAVAGGPMHYILLGMGEKWRPLAVLFAVAGVLVALLGIG
                     TFTQVNSITESIQNTTTISPVITALVLSVFVAIAVFGGLKSISKVSTTVVPFMTIIYI
                     LGTLIVIFFNIGKIPGTIALVFTSAFSPLAAVGGFAGASVRMAIQNGVARGVFSNESG
                     LGSAPIAAAAAKTNEPVEQGLISMTGTFIDTLIICTLTGLTILVTGVWSGDLNGVALT
                     QSAFSTVFSHFGPALLTIFLVLFAFTTILGWNYYGERCFEFLFGVRFIWLYRVVFVLM
                     VLLGGFIELDMVWIIADIVNALMALPNLIALLVLSQVVIAETKKYFDK"
     regulatory      complement(62696..62784)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00504"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="glycine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="glycine"
                     /db_xref="RFAM:RF00504"
     gene            complement(62948..65284)
                     /locus_tag="VQ865_000063"
     CDS             complement(62948..65284)
                     /locus_tag="VQ865_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HET3134497.1"
                     /translation="MNKKILETLEFDKVKALFEPHLLTEQGLEQLRQLAPTAKADKIK
                     QAFAEMKEMQALFVEQPHFTILSTKEIAGVCKRLEMGADLNIEEFLLLKRVLLASREL
                     QNFYANLENVSLEELALWFEKLHDFPQLQGNLQAFNDAGFIENFASEELARIRRKIHD
                     SESQVRDVLQDLLKQKAQMLTEGIVASRNGRQVLPVKNTYRNKIAGVVHDISASGNTV
                     YIEPREVVKLSEEIASLRADERYEMLRILQEISERVRPHAAEIANDAWIIGHLDLIRA
                     KVRFIQERQAVVPQLSENQEIQLLHVCHPLVKNAVANDVYFGQDLTAIVITGPNTGGK
                     TIMLKTLGLTQVMAQSGLPILADKGSRVGIFEEIFADIGDEQSIEQSLSTFSSHMTNI
                     VDILGKVNQHSLLLLDELGAGTDPQEGAALAMAILEDLRLRQIKTMATTHYPELKAYG
                     IETAFVQNASMEFDTATLRPTYRFMQGVPGRSNAFEIAKRLGLSEVIVGDASQQIDQD
                     NDVNRIIEQLEEQTLESRKRLDNIREVEQENLKMNRALKKLYNELNREKETELNKARE
                     QAAEIVDMALSESDQILKNLHSKSQLKPHEIIEAKAKLKKLAPEKVDLSKNKVLQKAK
                     KKRAPKVGDDIVVLSYGQRGTLTSQLKDGRWEAQVGLIKMTLEEKEFDLVQAQQEKPV
                     KKKQVNVVKRTSGRGPQARLDLRGKRYEEAMNELDTFIDQALLNNMAQVDIIHGIGTG
                     VIREGVTKYLQRNKHVKSFGYAPQNAGGSGATIVTFKG"
     gene            complement(65388..65936)
                     /locus_tag="VQ865_000064"
     CDS             complement(65388..65936)
                     /locus_tag="VQ865_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HET3134498.1"
                     /translation="MISFLLLLVLVWGFYIGYRRGLLLQVYYLISAMASAFMAGQFYK
                     GLGEQFHLLLPYANSQEGQGTFFFPSDQLFQLDKVFYAGIGYLLVFGIVYSIGRLLGL
                     LLHLIPSKKLGGKLFQVSAGILSMLVTLFVLQMALTILATIPMAVIQNPLEKSIVAKH
                     IIQSIPVTTSWLKQIWVTNLIG"
     gene            complement(65933..66235)
                     /gene="zapA"
                     /locus_tag="VQ865_000065"
     CDS             complement(65933..66235)
                     /gene="zapA"
                     /locus_tag="VQ865_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HET3134499.1"
                     /translation="MANLNRFKFTFGKKSLTLTSEHDNLFMEEIAKVATEKYQAIKEQ
                     MPSADDETIALLLAVNCLSTQLSREIEFDDKEQELEELRHKLVTCKQEQSKIEDSL"
     gene            66322..67194
                     /locus_tag="VQ865_000066"
     CDS             66322..67194
                     /locus_tag="VQ865_000066"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HET3134500.1"
                     /translation="MASITLTPSEKDIQAFLEHYQTSLAPSKNPYIRYFLKLPQATVS
                     IYTSGKILLQGEGAEKYASFFGYQAVEQTSGQNLPLIGTDEVGNGSYFGGLAVVAAFV
                     TPDQHDFLRKLGVGDSKTLTDQKIRQIAPILKEKIQHQALLLSPSKYNEVIGDRYNAV
                     SVKVALHNQAIYLLLQKGVQPEKIVIDAFTSAKNYDKYLAQEANRFSNSISLEEKAEG
                     KYLAVAVSSVIARDLFLENLENLGRELGYQLPSGAGTASDKVASQILQAYGMQGLNFC
                     AKLHFKNTEKAKNA"
     gene            67206..67820
                     /gene="lepB"
                     /locus_tag="VQ865_000067"
     CDS             67206..67820
                     /gene="lepB"
                     /locus_tag="VQ865_000067"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HET3134501.1"
                     /translation="MNLFKNFLKEWGLFLLILSLLALSRIFFWSNVRVEGHSMDPTLA
                     DGEILFVVKHLPIDRFDIVVAHEEDGNKDIVKRVIGMPGDTIRYENDKLYINDKETDE
                     PYLADYIKRFKDDKLQSTYSGKGFEGNKGTFFRSIAQKAQAFTVDVNYNTNFSFTVPE
                     GEYLLLGDDRLVSSDSRHVGTFKAKDITGEAKFRLWPITRIGTF"
     gene            67948..70314
                     /locus_tag="VQ865_000068"
     CDS             67948..70314
                     /locus_tag="VQ865_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HET3134502.1"
                     /translation="MEVYFSGTIERIIFENPSNFYRILLLEIDDTDAEDFDDFEIIVT
                     GTMADVIEGEDYTFWGQIVQHSKYGEQLQISRYDRAKPTSKGLVKYFSSSHFKGIGLK
                     TAQKIVDTYGENTIDEILQHPEKLEGIAGFSAKNREAFVSTLRLNYGTEMVLSKLANY
                     GIPNKLAFQIQDFYKEETLDVVENYPYQLVEDIKGLGFTIADQLAEELGIESQAPERF
                     RAGLVHSLFQACMETGDTYVEARDLLEQTLTLLESSRPVELDPSQVAQELSYLIEEDK
                     VQQIDTKIFDNSLFFAEEGIRSHLIRILEKGKQKSQDLETIQKHITTVEQELGIEYDN
                     IQKQAICDAIQNKVFILTGGPGTGKTTVINGIIAVYALLEGLDLRKKSNLPILLAAPT
                     GRAARRMNELTGLPSATIHRHLGMTGDDDTSHLEDYLDADFIIVDEFSMVDTWLANQL
                     FSNISSNSKILIVGDSDQLPSVSPGQVLADLLHIPLIPQTRLEKIYRQSKESTIVTLA
                     SQIRQGILPADFTQKKADRSYFEIASGHIPATIEKILGVALRNGIPARDIQVLAPMYR
                     GTAGIDAINQLMQDLLNPPQKDQLSFEAPQCHYRKRDKVIHLVNDAEINVFNGDLGAI
                     TDLIPGKYTESKQDEIVIDFDGNEVSYPRNEWYKIRLAYAMSIHKSQGSEFPVVILPI
                     TSASRRMLERNLIYTAITRAKSKLILLGELQAFDYATQHIGTARKTYLIERFSDLLEN
                     VEEKQQAVSETVTSSASEQSYILTEENWDRIPAMIGITDTDLKEIFGK"
     gene            complement(70362..71645)
                     /locus_tag="VQ865_000069"
     CDS             complement(70362..71645)
                     /locus_tag="VQ865_000069"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HET3134503.1"
                     /translation="MSVSFENKETNRGVLTFTISQDQIKPELDRVFKSVKKSLNVPGF
                     RKGHLPRPIFDKKFGEESLYQDVMNALLPNAYEAAVKEAGLEVVAQPKIDVTSMEKGQ
                     DWVIAAEVVTKPEVKLGDYKNLEVSVDVEKEVTDADVEERIERERNNLAELVIKEAAA
                     ENGDTVVIDFVGSIDGVEFDGGKGENFSLGLGSGQFIPGFEDQLVGHSAGETVDVIVT
                     FPEDYQAEDLAGKEAKFVTTIHEVKAKEVPALDDELAKDIDEEVETLADLKEKYRKEL
                     AAAKEEAYKDAVEGAAIDTAVENAEIVELPEEMIHEEVHRSVNEFLGNLQRQGINPDM
                     YFQITGTTQEDLHNQYQAEAESRTKTNLVIEAVAKAEGFDASEEEIQKEVEQLAADYN
                     MEVAQVQNLLSADMLKHDITIKKAVELITSTATVK"
     gene            complement(71806..72198)
                     /locus_tag="VQ865_000070"
     CDS             complement(71806..72198)
                     /locus_tag="VQ865_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3134504.1"
                     /translation="MDSPKSLASYRVIGISDRVLEILKEYLLLEEGDYIFTNNGSPLM
                     ITCFNYFLKNSFRKSEIKKDDFVLTAHVFRYSHISLLAELEVPITAIMDRVDYTNETK
                     ILSVYTHVTEKMKSNITEKLDKLVLEND"
     gene            complement(72497..73126)
                     /locus_tag="VQ865_000071"
     CDS             complement(72497..73126)
                     /locus_tag="VQ865_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3134505.1"
                     /translation="MVLSKYYGVADGMNVEGRGSANFIKDNVLITAAHNYYRHDYGKE
                     ADDIYVLPAVSPSQELFGKIKVKEVRYLKEFRNLNSKDAREYDLALLILEEPIGAKLG
                     TLGLPTSQKNLTGITVTITGYLSYNFKIHQMYTDKKQVLSDDGMFLDYQVDTLEGSSG
                     STVYDASHRVVGVHTLGDGANQINSAVKLNERNLPFIYSVLKGYSLEGW"
     gene            complement(73171..73410)
                     /locus_tag="VQ865_000072"
     CDS             complement(73171..73410)
                     /locus_tag="VQ865_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134506.1"
                     /translation="MKKTVYKKLGISIIASTLLASQLSTVSALSVISSTGEEYEVSET
                     LEKGPESNDSSLSEISPTYGSYYQKQSEVLSVMMI"
     gene            complement(73560..73826)
                     /locus_tag="VQ865_000073"
                     /pseudo
     CDS             complement(73560..73826)
                     /locus_tag="VQ865_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060522.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
     gene            complement(73851..74162)
                     /locus_tag="VQ865_000074"
     CDS             complement(73851..74162)
                     /locus_tag="VQ865_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3134507.1"
                     /translation="MDWDFADTCWEKDPREYQYVAANYLKAMQSYLKETDLPKLEQLV
                     VTKSWWDTVDILDRVVGSLVYEHSELEEIILILFENLFKPRQLYLQPQNSVLSNLRLA
                     S"
     gene            complement(74087..74329)
                     /locus_tag="VQ865_000075"
     CDS             complement(74087..74329)
                     /locus_tag="VQ865_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HET3134508.1"
                     /translation="MSLADLLEELEAAKDSKKARSMEAYMRHQFSFLGIAVPERNKLY
                     KNIFQKRKKQRLSIGILQTLAGKRILENTNMWLLTI"
     gene            complement(74330..74962)
                     /locus_tag="VQ865_000076"
     CDS             complement(74330..74962)
                     /locus_tag="VQ865_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3134509.1"
                     /translation="MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEASNGSQGIDLALE
                     LRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIVTSYLDNEKIMPVLDAGAKGYML
                     KTSSADELLHAVSKVAAGELAIEQEVSKKVEYHRNHMELHEELTARERDVLQLIAKGY
                     ENQRIADDLFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEEF"
     gene            complement(74976..75971)
                     /locus_tag="VQ865_000077"
     CDS             complement(74976..75971)
                     /locus_tag="VQ865_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3134510.1"
                     /translation="MKKQAYVIIALTSFLFVFFFSHSLLEILDFDWSIFLHDVEKTEK
                     FVFLLLVFSMSITCLLALFWRGIEELSLRKMQANLKRLLAGQEVVQVADPDLDASFKS
                     LSGKLNLLTEALQKAENHSLAQEEEIIEKERKRIARDLHDTVSQELFAAHMILSGISQ
                     QALKLDREKMQIQLQSVTAILETAQKDLRVLLLHLRPVELEQKSLIEGIQILLKELED
                     KSDLRVSLKQNMTKLPKKIEEHIFRILQELISNTLRHAQASCLDVYLYQTDVELQLKV
                     VDNGIGFQLGSLDDLSYGLRNIKERVEDMAGTVQLLTAPKQGLAVDIRIPLLDKE"
     gene            complement(75968..76666)
                     /locus_tag="VQ865_000078"
     CDS             complement(75968..76666)
                     /locus_tag="VQ865_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HET3134511.1"
                     /translation="MRKFKIFLFIEACLLTGALILMVSEHFSRFLLILFLFLLLIRYY
                     TGKEGNNLLLVAATILFFFIVMLNPFVILAIFVAVIYSLFLLYPMMNQEKEQTNLVFE
                     EVVTVKKEKNRWFGNLHHFSSYQTCQFDDINLFRFMGKDTIHLERVILTNHDNVIILR
                     KMVGTTKIIVPVDVEVSLSVNCLYGDLTFFNQPKRALRNEHYHQETKDYLKSNKSVKI
                     FLTTMIGDVEVVRG"
     gene            complement(76743..77753)
                     /locus_tag="VQ865_000079"
     CDS             complement(76743..77753)
                     /locus_tag="VQ865_000079"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HET3134512.1"
                     /translation="MTTNRKDEHILYALEQKSSYNSFDEVELIHSSLPLYNLDEIDLS
                     TEFAGRKWDFPFYINAMTGGSNKGREINQKLAQVAESCGILFVTGSYSAALKNPTDDS
                     FSVKSSHPNLLLGTNIGLDKPVELGLQTVEEMNPVLLQVHVNVMQELLMPEGERKFRS
                     WQSHLADYSEQIPVPIVLKEVGFGMDAKTIERAYEFGVRTVDLSGRGGTSFAYIENRR
                     SGQRDYLNQWGQSTMQALLNAQEWKDKVELLVSGGVRNPLDMIKCLVFGAKSVGLSRT
                     VLELVETYTVEEVIGIVQGWKADLRLIMCSLNCATIADLQKVDYLLYGKLKEAKDQMK
                     KA"
     gene            complement(77737..78744)
                     /locus_tag="VQ865_000080"
     CDS             complement(77737..78744)
                     /locus_tag="VQ865_000080"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HET3134513.1"
                     /translation="MIAVKTCGKLYWAGEYAILEPGQLALIKDIPIYMRAEIAFSDSY
                     RIYSDMFDFAVDLRPNPDYSLIQETIALMGDFLAVRGQNLRPFSLKICGKMEREGKKF
                     GLGSSGSVVVLVVKALLALYNLSVDQNLLFKLTSAVLLKRGDNGSMGDLACIVAEDLV
                     LYQSFDRQKVAAWLEEENLATVLERDWGFFISQVKPTLECDFLVGWTKEVAVSSHMVQ
                     QIKQNINQNFLSSSKETVVSLVEALEQGKAEKVIEQVEVASKLLEGLSTDIYTPLLRQ
                     LKEASQDLQAVAKSSGAGGGDCGIALSFDAQSTETLKNRWADLGIELLYQERIGHDDK
                     S"
     gene            complement(78731..79684)
                     /gene="mvaD"
                     /locus_tag="VQ865_000081"
     CDS             complement(78731..79684)
                     /gene="mvaD"
                     /locus_tag="VQ865_000081"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HET3134514.1"
                     /translation="MDREPVTVRSYANIAIIKYWGKKKEKEMVPATSSISLTLENMYT
                     ETTLSPLPANVTADEFYINGQLQNEVEHAKMSKIIDRYRPAGEGFVRIDTQNNMPTAA
                     GLSSSSSGLSALVKACNAYFKLGLDRSQLAQEAKFASGSSSRSFYGPLGAWDKDSGEI
                     YPVETDLKLAMIMLVLEDKKKPISSRDGMKLCVETSTTFDDWVRQSEKDYQDMLIYLK
                     ENDFAKIGELTEKNALAMHATTKTASPAFSYLTDASYEAMDFVRQLREKGEACYFTMD
                     AGPNVKVFCQEKDLEHLSEIFGQRYRLIVSKTKDLSQDDCC"
     gene            complement(79666..80544)
                     /gene="mvk"
                     /locus_tag="VQ865_000082"
     CDS             complement(79666..80544)
                     /gene="mvk"
                     /locus_tag="VQ865_000082"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HET3134515.1"
                     /translation="MTKKVGVGQAHSKIILIGEHAVVYGYPAVSLPLLEVEVTCKVVP
                     AESPWRLYEEDTLSMAVYASLEYLDITEACIRCEIDSAIPEKRGMGSSAAISIAAIRA
                     VFDYYQADLPHDVLEILVNRAEMIAHMNPSGLDAKTCLSDQPIRFIKNVGFTELEMDL
                     SAYLVIADTGVYGHTREAIQVVQNKGKDALPFLHALGELTQQAEVAISQKDAEGLGQI
                     LSQAHLHLKEIGVSSPEADFLVETTLSHGALGAKMSGGGLGGCIIALVTNLTHAQELA
                     ERLEEKGAVQTWIESL"
     gene            complement(80666..80788)
                     /locus_tag="VQ865_000083"
     CDS             complement(80666..80788)
                     /locus_tag="VQ865_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein C"
                     /protein_id="HET3134516.1"
                     /translation="MTTGWFQVNGRWYYAYSSGALAVNTIVDGYSVNYNGEWVR"
BASE COUNT        24457 a        18016 c        14818 g        23849 t
ORIGIN      
        1 acaatctcaa aacactgttt tgagcaacct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt attagtcctt tttcaaactt cctgcacgag tttgggttcc tgcataggca
      121 agtaagagaa gagttcctgc aatagctaca gatacaccat tggcaattcc cgcaacaatc
      181 ccttgtgcaa atactttttc tgccgcttct tgataaatca caacatctcc aagtggtgcc
      241 aagacacccc aaacaagggc atttgcaagt agttgaatga ggttaaaaat aagaatatct
      301 ttccagtcaa aaacaccatt gatcactcga acgtactttc taaaaagtcc cacaactaga
      361 ccaaaaagtc cgctagcgat aatccaagtc caccatagac cataaccagc aagagagtcc
      421 ttgattgcat gaccaatcaa cccgacaagc aaaccgataa tcggtccaaa aataatagaa
      481 agtagcgctt gtaccgcata ctgaagctgg atgcttgtat ttggaacagg ggttggaatg
      541 ttgatcatcc cgatgacgac aaagagggca gcgccaattc cgacagcaac aacttgttta
      601 attgtaaatt tgatttccat actattctcc tattttatcc ttctattttc tttatttcaa
      661 tggtccaaga tgaaccgaca cctacattat aggccttggc aaaggaacct tggttgatag
      721 ccaaacctaa acgatagaga gagttgatgt aaaggatggg ttgcccaatt ctcacatctg
      781 caaatgattt gccatagaca acctgatttt gatagaccag catatcagca tgatagatgg
      841 tcacttcaaa acgatcacca aattctggtt ccagcttgta aaattcttcc cgtgtgatag
      901 aggtccaaag cgaaccgaaa cgcacatcca gaatatcaat ggctcccttc accagatgat
      961 cttctatgat ggtcgctacg actggaagct ctacaatctg ttccacactg agctctggcc
     1021 ctacttcctc aaaagtaatg tgaccactgg ccagtttagc accagtatag gcatagacat
     1081 cacgaccgtg gaaggtataa gaatgctctg tgttttgacg cctattggcc acctcagaaa
     1141 tctcacgaat ggctacaatg ccaacgtgtt tcttgataaa ggaaagcgtc ccattatctg
     1201 gcgtgacaat gtattgattt tttgcagtct tggcaactac actcttacgt ttcgaaccga
     1261 cacctggatc gacaaccgat acaaacgtcg ttccctcagg ccagtaatcc accgtctgaa
     1321 agagacgata gctcccctca aaaatattat aaggcgtgat atcgtgcgtc aagtgatgga
     1381 tttttaaggt tggagactct tctaaagcca ctccaatcat agccgatacc gcaccatcaa
     1441 ccagaccaaa gtctgattgt aataccagta aattattatt cattttatct ccttgtatat
     1501 cctttatcat accatatttc agagaaagtc gctaatagct atttcaattg gttagggtat
     1561 agttttacct tatagcgaat tttcactaaa agctcttgtt attagctagt aggtgcattt
     1621 tttcttgaaa aagggtatga tagttacatc atgaaaaagt aggttttatt atgaaaatta
     1681 tccttgtcgg agggggaaaa gttggttttg ccctctgtcg ctccttggtt gcagaaaagc
     1741 atgatgtttt gctgattgag caagacgaag ctgttctcaa tcatattgtc aatcgctttg
     1801 atatcattgg tatccttggt aacggggccg attttgccat tcttgagcaa gccagcgtcc
     1861 aagattgtga tatctttatc gccctgactg agcacgatga agtcaacatg attgcagcag
     1921 ttctagccaa gaaaatggga gctaaagaaa ctatcgttcg ggtgcggaac cctgaatatt
     1981 ctaactctta tttcaaggaa aagaatattc tcggtttttc tcttatcgtt aatcctgagc
     2041 tcttggctgc ccgcgctatc gcgaatatca ttgacttccc caacgccctg tctgtcgaac
     2101 gctttgctgg tggacgcgtt agcctcatgg aatttgtcgt caagtccacc agcggtcttt
     2161 gccaaatgcc catttctgat tttcgtaaaa aatttggtaa tgtcattgtc tgtgcgatag
     2221 agagggatca tcaaattatc attccaagcg gtgacatgac tgtacaggat aaagatagaa
     2281 tctttgtcac tggtaaccgt gtcgatatga tactcttcca taattatttt aaatcacgcg
     2341 ccgtgaagag ccttctcatc gttggggcag gtagaattgc ctattatcta cttggtattc
     2401 tcaaagatag tcgtatcgat acaaaagtca ttgaaatcaa tcctgaaatc gccagcttct
     2461 ttagcgagaa attcccaaat ctctacatcg ttcaaggaga tggaaccgca aaagatatcc
     2521 tgctggaaga aagtgctcaa cactatgatg ccgttgcgac tctaacaggt gtcgatgagg
     2581 aaaatctgat tacatctatg ttccttgaca gggtaggtgt acagaaaaat attactaagg
     2641 tcaatcgtac cagtctcctc gagattatca atgcgcctga tttttcaagt atcatcacac
     2701 ctaaaagcat cgctgtagat acgattatgc actttattcg tggtcgagtt aatgcccagt
     2761 attcagacct tcaagccatg caccatctag ccaatggcca aattgaaacc ctgcaattcc
     2821 atatcaagga agccaataaa atgactgcca aacctctttc tcaactgaaa ttgaaaaaag
     2881 gggttcttat tgcagccatt attcgaaagg gcaagactat tttcccaact ggggaggata
     2941 tgttggaagt tggagacaag ctcctagtaa caaccttgtt gccaaacatc accaagattt
     3001 atgacttgat tgcgaggtaa gaaatgaata aaagtatgat tcgttacctc ctttcaaagt
     3061 tacttttgat tgaagctgtt ctcctcttgg ttcctgtggc tatcgctgtc tattaccgtg
     3121 aatcgagcca agtctttaca gccctctttt cgaccatagg gattctcgta ttgttaggcg
     3181 gttcagggag tttacagaag ccaaaaaatc aacggattta tgccaaggag ggagtcttga
     3241 tcgttgccct ctgttggatc ctttggtctt tctttggtgg tctccccttt gtcttttctg
     3301 ggcaaatccc tagcgttatt gatgcctttt ttgaaattag ttctgggttt acaactactg
     3361 gagcaagtat tttgaacgac atttcggttc tcagccgttc cctcctcttc tggcgaagtt
     3421 ttacccactt gattggaggg atgggagtgc ttgtttttgc acttgctatt atggacaatg
     3481 ccaaaaatag ccacctagag gtgatgaagg ctgaggttcc aggtcctgtt tttggcaagg
     3541 ttgtatccaa actaaaaaac actgcccaga ttctctatct cctttatcta gctctcttct
     3601 ccctctttgt catcatctat tatctagctg gtatgcctct ctacgatagt tttgtcattg
     3661 ctatggggac agcgggaact ggaggcttta ccgtctataa cgacggaatt gcccactatg
     3721 gcagctcact gattacctat ctggtcagta tcggagttct ggtttttggg gtaaatttca
     3781 acctctacta ctacctcatg ctccgtcgca tcaaggcctt ctttggtgac gaagaacttc
     3841 gggcttactt ggtcattgta ctggtttcta caggcttgat tagcctcaac accctctacc
     3901 tctacccagg gttttcaaag agctttgaaa tgaccttctt ccaggtttcc aacatcatta
     3961 caacaactgg ttttggatat ggagatatta ccaactggcc cctcttctcc cagtttatcc
     4021 tccttttcct catggcaatc ggtggctctg ctggatcaac tgcaggtgga ctcaagatta
     4081 ttcgaggcct catcctttca aaaattgcca aaaaccaaat tttgtcaatc ctatcgcccc
     4141 accgtgtttt gaccctccat gttaataaaa cggtgattga caaagatacc cagcataaga
     4201 ttctcaagta ctttgtcatc tatgctatga ttttgctagc gcttatcttt attgtcagcc
     4261 tagatagcaa tgattttctg gtcgtgacca gcgctgtctt tagctgtttc aataatatcg
     4321 ggcctattct aggaaccact tctagtttct caatctttag tcccatctca aaaattctcc
     4381 tatcctttgc aatgattgca gggcgcttgg agatttaccc aatcctcctt ctctttatga
     4441 agagaacttg gtctaagaga taaaatacaa aatccctctt tttacaattg tgaaagaggg
     4501 attcttatat taaaaaaggg ggaacgtttt taaatccaag cctatctgta agcaaaatct
     4561 ttactcaaat aaaagatgga aaaacttact acacagcttg gtaatgctcc aatacaaatt
     4621 gtaaggcttt acttggactc tttgttaaat gaatatattc cattcctctg gtagcaacta
     4681 tctgaatacc taatctttct gcatccacct tcatctctct ataataactc cgaacttgtg
     4741 gggccagaat aattaaatca taaacaccca taatatcata atgagctccg tacgctcctg
     4801 aattcgcaat cactctaact tctgctaatt gagcgccctc gttaattgca ttggctaatt
     4861 gcgcacttgt tccagaccct gcacaaagaa ccagtacttt caactcctta ctttttatta
     4921 catctatctc acaaggcatt atttcacttg tatcctcctc taaaataata tcatttgagc
     4981 ttgcaatatc ttctttcacc agtaactgtc tatcatacgc tctacagaat ggcaaataaa
     5041 tcaatatgtc gacaactaac atcaaagata aaaatacaaa ggagataagt tgaaaattcg
     5101 ttccaattaa caatcccaag ggaccaggaa aggcccaagg taactggata taaaatccat
     5161 tcattccaaa gaaatcaata aatacctttc ctagaaatac attcactggt ggagtcatca
     5221 aaaaaggtac aaaaagatag ggattcaaaa taacaggcat accaaataga agaggttcat
     5281 ttaccgcaaa taaaacagga gtaattgtag ctttacctac cgattttaat tgtttagacc
     5341 gcataaagaa aatcaaaata aatggtacaa caaaggtagc ccccgttcct ccaatagcag
     5401 cgatataatt cccgaaatta ggtgttaaag aatgataagg gaactgccca tttgcaagaa
     5461 gttgagcatt ctcttccata ttgctcagtt gtaaagctgt aacagcaggt aagacaatag
     5521 atggtccatg aattccaaca aaccaaagca aagcacacat aaaccaaatc aacatcatag
     5581 caggatatga ttctgccccc ttaaaaatag gagtcaatag ttgttgaaat acttgggcaa
     5641 aaggaacatc taaactaaaa cgagatacaa tatctaacaa accactaata agtaaaacaa
     5701 aagaaaaagg aaaaatatct ctaaaagctt gtgatatagc cccaggaact tccttaggta
     5761 aatgaatagt aatgtctcgc ttaatacaga atcggtaaac atttacagta ataaaggcac
     5821 tgacaaacga agttatcaat ccttgagatc ctaaatagtt tgtcgacaaa cttgtagatc
     5881 ccgttttctc atcaactaca agcgttacag ttaatacaag atagccacat atggccgcca
     5941 acattgcaga agtatcattt attacctttc caggaggcat ttttctatta acatttccag
     6001 ccaatgactt tgcaactgtc cctgaaacaa taatacccaa aactcccatg gttagcatat
     6061 acactttcct catccaggca atagctggac tcggtaactc tactccgaaa tttttaggaa
     6121 tcataataat aatcatcaaa aagcttgaaa acataattaa aggcatagta gcaataaatc
     6181 catctttaat agccatcata taattattag tagaaatttt ttcaaatttc ccttgttgct
     6241 tttcaatggc agcgactaac ttatccataa aaactcctcc tgtaaaaaat ttaagctcat
     6301 agttaaaata tattaaacat cagtcaaatc gctaacctta attccgtttt agccctttta
     6361 cccaaagagc acttttctta atatatctct tctgtgtttc ataatcaaca aagaaaagac
     6421 catatcgctt attgtagcca ttcgcccaag aaaattgatc ttgcaaagac catataaaat
     6481 agccttgaat attgactcct ctatctcgag cctctaaaac tttgtgtaaa tgttgctcaa
     6541 tataacggat tctcttactg tcatcaataa tatcattctc gccctctggc ttaacttctt
     6601 taagggctgt accattttca gttaaataaa tgaccggatg ttgaggatat tcttctttga
     6661 tacgaagcaa catatcaaat aacccttgag gataaatatt ccaatcccaa tctgttgtcg
     6721 gaataccagg tttttttaca aattcaccta gagcatttaa tttaaaagaa gactgtcctt
     6781 ttattcctgt tgaattaaat tcttgtctat tttcaccttt gtattcacga ataaattctg
     6841 aacgataata attcatccca aacatcgtat taagagctgc agctctcttc ataatttcta
     6901 aatcaccatc ttcaataata aagctagaat tattagcttc caatatttga ttcaagtgaa
     6961 aaagcgtgtc ctcactgtag tagcccaaaa aagttccatc taatagaaat ttattattat
     7021 aaacatcata ccgtttagct gccaaaatat tttctttttg cccatcaata ggatagcctg
     7081 gctttaaagc atgaatacaa cctatctttc cctcaatccc taattgatga aattcgcgga
     7141 ctgcaagagc atgcgccaac aacatattat gattcgcttg aattgcttca gataattgaa
     7201 aatgatgatt tggaggaaac tgacctccta tatattgacc tgcagcaaga gacatcagtt
     7261 cattgattgt aaaccaatgc ttgacttctg taaattcttg gaaacaaaag cgagcatatc
     7321 gtatgaaacg atcaatattc tctctattca accaatcccc tgtttctaac attttctgag
     7381 gcgaatcaaa atgatgtaaa gaaacaaacg gaatcacatt atgttttaag caagactgaa
     7441 agactctatg gtaataacga acagctaata tattaggctc cccatctata tcaggaaata
     7501 tacgaaccca agaaatagat aaacgcaaag cctgcaaacc atgttctgcc gccaaagcta
     7561 tatcctcttc gtaacgataa taaaaatcac tagccggatc tggtaaaaac ggactgtttt
     7621 cttgcaaata aacatcccac atatttgttc ctttgccatc taccctagtt gcaccctcta
     7681 cttgataagc agcggtagca gctcctaata aaaactcctt cggtaaggct ttaacctgta
     7741 aattttccat gactaatcct cattgcaaac caatatgttc ttcaatcttt cgaattcgtt
     7801 catattcatc aataaaaaac ttgacctgat catacaatag catcgttgtc atcaaggtat
     7861 cttgaccatg aatcatgata aaactcactt caaaattatc tccagatgcc tcctccgcta
     7921 ataaattagt ctgttctcga tgggcagaca ctattgagtc gtttgcagac tcaaccaatt
     7981 ctcttgcctg ttcaaaatat ccatctctcg caaacgccaa agcatccatc aaatctgacc
     8041 ttgcatctcc tgcgtaagcg acaattgtaa aaccaagcat atttatttct tcttttgatt
     8101 tcatctttct tcctcctcaa tcttgatcca tcttttacac atcattatta aaatgacttc
     8161 gctacgatat aaatagaaag tcgaccctaa atatcttaaa aatccttaaa tttcataata
     8221 tttaggatca atcttctctg aataccttgg ttcattttct atacttatga tttataagtg
     8281 gaaaccagcg taattttttg ctacttcaat tacacgataa acatccaaat tagattggaa
     8341 tagcagttcg tgcccacgga tataattcaa cacatttctc cattcatctt gagcttgcct
     8401 tgtttttccg gttgcttgaa gatataaagc cttcgccatc ttaacaacat attcacgatg
     8461 ataactgagc tgtttccatt catccttttg actatttaat aacttagaaa tattttcctc
     8521 aataattggc aaaaaattat cagctagatt gtaagctata taataatgat tcgctaaaac
     8581 atcattttga cgactgccaa ttgcattaaa ataatcacat gaggaataac tggataattt
     8641 ttctaaatat tcaacaacag actgccaatt tgacccatac aaagcagaaa agtattcttc
     8701 aatcaattct tcataacttc ttgtcttctt ccagagcatt tcccccataa cataattagg
     8761 aaaattatga gggaatccgg cacgtaattc ttgacacgaa atgtaaccgt tcaaatgtag
     8821 gttagaaaga taagatacat ctctgtaaat ggtttgacta attttcatat agcctaaatc
     8881 gccataatga gcacgcccta aaggatagtc atatacgaaa ctatctcctt taaatgtttt
     8941 ttgccactca aaaagataag ataaattttc ctcaagagaa ttcggaagta taattttatt
     9001 acgcagataa ggtttaggcg taggtatgga attgtcaaaa tctacatctg cataactcat
     9061 ttcaaatgtt cttgtaatcg gtgcaaacat catggtaaag cgttcaggat tatctaattt
     9121 ttctttctga ggcgcccata gcaactcatg gtaaagcaga aaacaaatct ttgtatctaa
     9181 tccctcactc gttaaagccc tatccaattg attgagaata cgaatatact gatccgaaac
     9241 caattcttgt ctacagtttt cgcattcaca aatattatta cgagcatccg acaaccatac
     9301 atgtaagtag ttaacatcag gtcttttctt ggcataatcc ttgataattt ctaccatctt
     9361 atcagctaca tctggatttg aaaaatccag gctggttaaa atcggagccg tattaaacaa
     9421 ttctcgtttc ccgtttattt cagcgacata gggtttcttc tcctctgaaa tactaagacc
     9481 tgattcccag ccaaattttg aagagtaacc taaaacttca cctgtccatc catgaccaac
     9541 acgatgatga ataagacctc ttttttgcaa ttctttatcc aacctatcac tcaattcttg
     9601 tactaattca tttgaaaatt gttctttatt tagatatgga ttaaattcat gttcatacca
     9661 acgtttcaaa aaagagtaag gattttcaaa ctggatgaaa aaactgttca tcccaatctt
     9721 aggtagccaa tcaatgaaat ctagtatatt ttcaaatgaa tccgctccct ctatacatac
     9781 tcccctatga tagtaactgg ctgtttcatc tatagatagc tgtttatcta aaaaatcttc
     9841 aaatcgtaac tctggaacaa agtcatgtct gcgccctggt ctagtataca caaccccaaa
     9901 ttcatgaaac attcggtaaa ttccaataag taaacctaca attgtattag actcaattct
     9961 tcccttaccc ttgtctaatg agataagaac atggtctttt ctgtcctctt tattgactaa
    10021 tcctacaaaa atatccgctt ccttctcctc gacaagctct atgttagtct taaagacccg
    10081 attcatatag taacttaatt cctctaaggc aaagctagaa taagtatttt tctgttgatc
    10141 aaatactctg ataaccatct tatttccctc caacagtagc tttttctttt tcaagattgc
    10201 gtttatctgc aattttgaag aatggataat aaattgctac agaaaccaaa atcaaaacaa
    10261 cttgtaatag agctcctcgc caactagccc ctgttgcaag gaagcctcct ataatcggtg
    10321 gcattgtcca cggaaggatt acacctgttg tatagggtac taatcctaca gccattgata
    10381 cataggtaat caaggcattg attgtaggag tagcaataaa cggaatcagc ataatcggat
    10441 ttaaaactgt tggaaacgta aatagaatag ctgtattgat attaaaaata gacggtataa
    10501 tagctagctt acctaatgtt ttattcgcac gactcttact aaataggaag agacaaatcg
    10561 caagaccaat agtcgctcca ccgccaccaa taaatacaaa taaatcttta aacggtaatg
    10621 taataatgtg ttggagtgtt tgtcctgcag ccacagcttc ttggttttct atagtaaatt
    10681 gtaaccaaac tggatctaca aaagcattta aaacttgtcc cccattaact ccacagaacc
    10741 aaaagaatga gtttacaata acacatagaa tcatacctgg aagcgttcct gcaattaact
    10801 taagcggtgt tccaacaatt ccacctagga gtccgttgag acctcctgca actcctgccg
    10861 cttcaagacc ttttaagacc agagcccaca aaacaaaagt agtaaagcca ggtaaaagag
    10921 ctgaaaatga tttacttacc acatctggga caccacttgg catttttatc gtaattccgc
    10981 gctggataaa catacgataa atctctgctg taaccaatcc aatagtaatc gccataaaca
    11041 aagaagatgc attcaggcta gaaaatggta ttgcgccgcc aaataactgc ttgacctgct
    11101 ccccattttt atcataaacc atactcgaaa aacgaggtgc catcaataca aaactggata
    11161 aggctatgat ccctgccgac ggaccatctg taccatatcc ttccgacaac ctgtaggcaa
    11221 taccgaaaca agcgaccaag gagataatcg ctactgttga ctgattcata gttgtcaaga
    11281 tacttagcaa tccaacacta ttcagccaat ttgtaaaatc ctcttgaggc caactgatta
    11341 gaataagaaa taaagatccg actaaaatca aaggcattgc catcataaat ccttcacgaa
    11401 tagctttcaa atgccgttgg ttgccaactt tttcaccaaa cggagcgact tttgtttcta
    11461 aaaacgctaa aatattgttc atcaccggaa ctcctttttt tattttttat aaattaaata
    11521 taccactaac agaaagcgtt gtcaatatat tttttgttgt ttttacaata tttttttctt
    11581 tgtatagaat aataatttta attgattttt tcttatgttt aatataaaat aaaccaaagg
    11641 aggaaacaaa tgattacaaa acaatcagcc tttttacaaa atagagccac tatactggag
    11701 tttctatatc gaaatccagc aacatcccgt acagatattg ttaatgaaac aggacttact
    11761 ccagcaacaa cgactaacat cataaaagag ctaagcgaac agtccctcat atacgaaact
    11821 ggtgatgaat ttagcgagtt ttccggatct ggaagacgta gaaaaactat ttctatcaca
    11881 gataatattc cgtatgttgt tggaggtatt gaaataaacg tcctaggtat ctttctcagt
    11941 ctatgtgact tacaagggaa aactcttttc gagacagaaa ttttgaatga agattatcct
    12001 atttcagaaa tcaattccac cattaccaat atgataaaaa cagctataga gtacgtccct
    12061 ttggaaacaa aattacttgg atttggctta tcaatacctg gacattataa caaagactcc
    12121 ggaagtatca ttacaaacaa ccccatatgg gaatctttta atttattaaa tgtaattaaa
    12181 agattcaatt ttccttttat tgtaaaaaat aatatcgatt gtatggctat aggacaatac
    12241 ctttttaatc cacacaatac ccccgataac tttattttcc tacacgctgg attaggtatt
    12301 tacacttcct ttttcacaaa agaaaaaata ggagcctcta aaaatcctta tatcggagaa
    12361 attggacaca ccattgtcga attgaatggg caatattgtg aatgcggaaa aaaaggttgt
    12421 ttacaaacat atatttcgga tgcttggtta atcaaacacg cccaattatt atttaaaaat
    12481 tcccaactaa ctgtactaaa aagccttgta aagactgaaa aagacattca tttagacacc
    12541 cttttaacgg cttataattt aggcgactcc gctttacgtc aacaaattga taaaggagtc
    12601 aatttattag ccacttctat tgcaaatctt ctcctcatca atcctgctga taaaatctat
    12661 atcaacagtc aattgcttaa ttatcaacct ttcactcatg aagtcaggga taaaatccaa
    12721 gaccagctcc acttcgttcc ctttactcgt aatatagaaa ttgaaatttt accttacaac
    12781 aaacatcgtg gaagtatagg agcttgtgca ttagctatcg ttgctttttt catagagcat
    12841 agcaatgtat tacaagatat tatttcacct taatatatat tagaaatcta tagacctgtt
    12901 taaatcaact ataacctgta gtaaatatct cgtatttaga caatatgaaa acaagacgac
    12961 ttccatatag gaaaccgcct tctctctatg ttgagtgatt tatattaaaa taacttttct
    13021 tctagctgca ttttattatt ataaaaacat tcatcataac ccccagaact taaataacaa
    13081 tttttattca agatacatac tcctagaata aactttatat gaaatcccca tttttgtttt
    13141 tacaattctc cttatactca atgaaaatca aagagcaaac taggaagcta gctgcaggct
    13201 gctcaaaaca ctgttttgag gttgtagata gaactgacga agtcagtaac atctatacgg
    13261 taaggcgacg ctgacgtggt ttgaagagat tttcgaaaag tattagttaa atcttgttta
    13321 atatctctac accatactat tttacatata ttatttagcg ccacatagta ctgaactctc
    13381 tccaaaaacg gttatgcctc tttgaatagg gcgttatcac aagaaaagca tctccacgtt
    13441 tcaacttcat atggctcaaa aacaatcaat tgatgctaaa acctgtacct agatgtttcg
    13501 gttcataaaa ccatgaaact gtaaaagtgg atgaaattga tagcgatagt caaatcaaga
    13561 ggcatcataa ctctaaaaag tcacaatata taagttcatc ctcggaaaaa tatcattcta
    13621 attgttgaaa tggatatata aacaggggta ttaacattaa atgctcatga aacaacgaat
    13681 acaggtatca aaactatgac aaaacaagtc cctaaattta ctaaagacac tgctcaactt
    13741 tacacctgta aatggttgtt gtataataaa gttacaaaga tgtacgacca cactgttgta
    13801 aatcatagtg ttcgcgaata tattactgat agcatttcta caaatacaat tgaagaggct
    13861 ggataggctt taaacgaaat atgtcagtgt tttggcattc ctagccttaa tatcatttaa
    13921 agaattgtat agataaaatt ttttccaata cagacactcg taacaactgc ttcatttttc
    13981 taccaacata tttaggaaca ggataagata caagaggatt aatccataaa tcagttctat
    14041 accaatctaa gacaaataag ctaaaaaaac gattgataat aagcaaatag attccaaatt
    14101 ttctctatct gctcatttta ataaacaata ctagtgtaac tatccttcca gtcagaaact
    14161 tgtcaaatca caccgaaaac tcttctaaaa tttatctcgt taggcaatca agcaaaaact
    14221 cgacgatagt acaaacatta tcatacagaa ttgactgcct aaattatata ctttagtaag
    14281 gttttcggat aagaaaaaag gttcatttta catttctaaa cattcttttc taagatgaaa
    14341 aacagaattt ttcgattgtg atttaaagca acaagaagat tttcagtatc atcctataga
    14401 tacgagctaa ttaagaaaaa ctacattttt gaatataaac tacaataata taaactaaat
    14461 tttataggag gaagacaatg gattggtacg attatatgat acaggcatcc aaacaatcac
    14521 aattcaacgc aagccattgg tttcgctatt tgcgaaaagt tatttttgaa gactattctt
    14581 atttaacaaa ccaagatgta gaaaagttgc tagactccaa agaactaacc cgttttcaaa
    14641 aaattagctt gaagtatgcc tttcaagagc atactccaac tcataaatat gtgatttcat
    14701 taaataaacc tgctaagtta accaatgttc aaaaattgat ggagaaatac aaacatggat
    14761 aaaatgaaac cggtcttcca agccctaaat aagaaattaa ttcaggaaaa tctgacttta
    14821 acaattatgg ttatgtctta gaatatcatg gtttacgtgc cacacaagat gttgatgctt
    14881 tttatgacca aaatcagaaa atcaatgaaa ttattgctcg tgtaggaaaa cagtttaatc
    14941 ttaacatcca cgaagagtta tggctcaaca atcatgttgc aaagcaaata tgaacaaaca
    15001 acctccctta agtttatgcg aatccttgta ctcatttgag aatctgaccg ttttagtagt
    15061 ccctattgag tatgtgttag gaatgaagat gatgagtatc agagagcagg atttgcaaga
    15121 tattggtgca attattaaat acaaaaactt tcattcacca ttcgatacct ttaaatattt
    15181 aaaagacatg ggatttgata ctattgacct ctctgttcta ttagaaggtt ttagttatgc
    15241 ttatggtatg gattggttag aaaaattttt taaagaaaat caagataaac ttcgcgaatt
    15301 ttattaacag tatcaaacaa gatgattgtc aattagccag tcgtcttatt tttatgatga
    15361 aatgaaatga aataaaatcg gaacaaatca cttagagaat tccagtcaat ttctagcact
    15421 gtttgagccg tttcagcgga ctatagtaaa atgaaataag aataggacaa atcgatcagg
    15481 acagtcaaat cgatttctaa gaatgtttta gaagtaaagg tgtactattc tagtttcaat
    15541 ctattatatt tcagattcgg tccactgttc cttcccaaaa acattgcata ttgcgccgaa
    15601 ggaattgctc atactatccc aagcacaaaa ccctcagtcg tttgaccgag ggttcctttt
    15661 tattattcaa gaacttgatt agctcaatgc atccaaggcg tcatccattg aaagaacttc
    15721 gtggaagaca cgttgtgtca attcagtttt ttgttctgga gtgaggtatt tagtgtttac
    15781 acagtatcca gagatacgta cgataacgtc ttcgcctgac atgatttttt cgtaaacatc
    15841 gttcaagtcc ataacgttca agttaacgtg ttgtccaccg ttttcgaagt aaccatcaag
    15901 gattgttacc aagttatcaa cttgttcatc acgagtctta ccaagagcgc gaggtgatac
    15961 ttgtgtagtc aatgagatac cgtcagctgc ataactaaag tcaaggctag aaagtgagtt
    16021 caagttttgc aaccaaccac ctttagcttt gttagatggg ttagcacctg gtgagaagaa
    16081 ttcaagttta gacaagttca cagaaccatc ttcgttgagg tatacacctt tgtgaactgg
    16141 tgagttacca gtttgtttag agtaagcaac gttagatgtg attgtcaaaa gtgatactgt
    16201 agcttctgcg tctttgtata gtttgtggct acgtagacga gttgtgtaag cttcgatcaa
    16261 ccattctgcc aattcgtttg aacgtgggtc atcttcaccc cagcgtgggt agtcaccgat
    16321 tgtttcgtaa tcgtagatgt agccatcttc gtcacggatt ggtttaactg tagcgtattt
    16381 gatagctgac aatgtatcaa cagtgttagc aaatccacag ataccgaatc ccatgttggc
    16441 acgttgttta gttggcaaga aggccatttg aacagcttcg tagttgtacc tatcagtcat
    16501 gtagtggatg atgttcaagg catctacgta agtgtcagtc aaccagtcaa gagatttttc
    16561 aaagttcgct ttaactgatt cgaattcaag aacttcgtca cgaataggat cgatgtcaaa
    16621 tactttgtag tctttgtgaa catcgtcgta accaccattc aaaccagtaa gaagggcttt
    16681 aagaacgttt acacgagcac cgaagtactg gatgttgtgg cgttgttctt cattttctgg
    16741 atcaagtgga gacacacagc atgagataca gctcatttca ccatatccgt ctttagccat
    16801 tgttgttaca ccttcgtatt ggatagaaga gtgtttgtgg ctcatgtgca tacagtagcg
    16861 acggaagttg tatggcaatt tgtcagtcca aagaactgtc aagtttggtt ctggtgagtt
    16921 accgatgttg tcaagagtgt tcaagaaacg gtagtccatc ttagtaacac ggtgacgacc
    16981 gtcgttaccc ataccagcca tagaagttgt gataaaggtt gggtcacctg agtacaattg
    17041 gtcataagct tttgtacgag caaatttaac tgtacgaagt ttcataacga aatcatcaac
    17101 gaattcttgg atttctgatt cagtaaatgt accacgagca aggtcacgtt ctgcaaagat
    17161 gtccaatacg attggtacac gacctagaga tgtagcagca ccgttaatca cacggcagac
    17221 agccatgaaa gcaatgttaa cccattggat tgcttctttc acgttcatcg ctggtttgcg
    17281 aacatcaacc ccgtaaaggt cacccaggcg aacaacttgt tgcaatgctt ggtattgaag
    17341 gtttacttct tcacgaagac ggattgtttc ttcatcgatt tctttgattg cattccagtc
    17401 gtttactttt tcttgcatca agtagtctgc accgtaaaga gcaagacgtg cgtaaacacc
    17461 gatgatacgt ccgcgtgagt atgcatctgg aagaccagtt acagtgtgtg catgacgagc
    17521 gcgacgaata tttgaagtgt aggcacggaa aataccgtcg ttaactgttg ttacatattt
    17581 agtgaagatt tcgtgaacag ctgggtctgg ttcgtatcca ttttctttta aagtagtttc
    17641 agccatacgg ataccacctt ttggcatgaa gttcaatttg aagagttcat cattttggat
    17701 accaaagata acttcatttt ctttgtcgat aaatccagca gggatatcag cgatagatgt
    17761 tggacgagtg tccattggga aacgagtttc ttcgtagtgt gctttagttt cttctacaat
    17821 tttcttgatg tgaagtgaac gctctgttgg tcctgcaagg aagctttcgt ctccatcata
    17881 aggtgtgtag ttagcttgta caaagcgtga tacacttgct ttttctttcc aatctacgcc
    17941 tttgaagcct tcccaagctt tgtcaaaaat atcttgtgct tcaacaaccg tcttaacaac
    18001 catattaatg tcctcttttt tctagtaaca gtcatctgtt acattcataa gacaagtata
    18061 ccataaagta atcgatttca acaagtgcaa aatccctatt tttacacttt cttttctaaa
    18121 acagtctata ttttatttca aactgtatta tatttttgaa aaaaataaag tccttttttc
    18181 tttttttcag aaaaaagggt ataataaaag aaaataagca gtaacactca atggaaatcg
    18241 aaaagcaaac taggaagcta gccgcaggct gctcaaagca ctgctttgag gttgtaaata
    18301 gaactgacga agtcagctca aaatactgtt ttgaggttgc agatggaagc tgacgtggtt
    18361 tgaagagatt ttcgaagagt ataaaaaggt gctaggcatg ttgatttttc ctttgttaaa
    18421 tgatttgtca agaaaaatca tccatattga catggatgcc ttttttgctg cggtggaaat
    18481 caaggataat cctaaactca gaggaaaacc tgtcattatt ggaagcgacc ctcggcaaac
    18541 aggtggacgg ggagtcgttt ctacctgtag ctatgaggct cgagcttttg gtgtccattc
    18601 tgccatgagt tccaaggaag cttatgaacg ttgtccccag gccgtcttta tctcaggaaa
    18661 ttatgagaaa tacaaagctg tgggactcca gattcgagct atttttaagc gctatacaga
    18721 tttgattgaa cccatgagca ttgacgaagc ctatttggat gtgacagaaa ataaactcgg
    18781 tatcaagtca gcggtcaaaa ttgctcgcct cattcaaaaa gatatctggc aagaactcca
    18841 tctaactgct tctgccggta tttcctacaa caagttctta gctaaaatgg cgagtgatta
    18901 tcaaaaacct catggtttga cagtgattct acctgaacag gctgagaatt ttctcaaaca
    18961 aatggatatt tccaaatttc atggagtagg aaaaaagaca gtagaacgtc ttcatcaaat
    19021 gggcgttttt actggtgctg atttacttga agttcctgag gtgaccctaa tagaccgttt
    19081 tggtagacta ggctatgatc tgtatcgaaa ggctcgtggc attcacaact ctccagtcaa
    19141 atccaatcgc atccgtaaat caatcggcaa ggagaaaacc tacgggaaga ttctccgtgc
    19201 tgaggaagat atcaaaaaag agctgactct tctatcagaa aaagtcgctc tcaatctaca
    19261 tcaacaagaa aaagctggaa aaattgtcat tttgaaaatc cgctacgagg acttttcaac
    19321 tcttaccaaa cgaaaaagtc ttgctcaaaa aacacaagat gctagtcaga taagccaaat
    19381 agccctgcaa ctctatgaag aattaagcga gaaagaaaga ggtgtccgcc tattggggat
    19441 taccctgact ggattttaaa gctcaatgaa aatcaaagag caaactagga agctagccgc
    19501 aggctgctca aaacactgtt ttgaggttgc agataaagct gacgcggttt gaagagattt
    19561 tctaagagta taaaaccttg aagagttgcc ccttcaaggt ttttcttata caaataaacg
    19621 gacaaaactg taaagtagca aaacactacc aagcacgata cggtatttac caaaaagggt
    19681 gaagtcgtgt tttttcacat agctggtcaa gaagcgaata gccaccatgc tgaccgcaaa
    19741 agctactccc atcgcgacca agagcaaaaa caattgccca aagctcaaga gttctccggc
    19801 tttcacaaat ttgaaaatct ttaaggcact agctccaaac ataacgggaa tcccaagata
    19861 gaaggtaaat tctgtcacaa ctgaacgact ggttccattt aacaaaccac cgacaatcgt
    19921 tgcacctgaa cggctagtcc ctggtaaaag agcaagaact tggaagagtc cgatatagaa
    19981 agcggtcgta taaggaagct tgtccaactc tgttacactt ggctcgatag cacgcgcttt
    20041 attgcgcttt tccaaataga tgaaggcaac cccgtagata atcaacatga gagcaactga
    20101 aaccatgtta tggaagtggg tatcaaacca atcatcaaat ttaaagacac caagtaaagg
    20161 caaagtggca atcaagacct tcaaccatag tctccaagtc ttacgaactt cctgtttgtc
    20221 cttagtcggt ttaaaaggat tgagcttgtt aaaataaatc accataactg ctaaaatagc
    20281 accaagctga atcacgacat taaacatgga cataaaggct tcattttgat tttggtattg
    20341 gataaactcc tctgctaaaa tcaagtgacc tgtactggaa atcggcaacc attccgtaat
    20401 tccttcaaca atcccgaaga agatagattt taaaatttca ataagataca tatatttctc
    20461 cttatattat atttaacgca gttagctact gccaaagccc aagtggtata cttggaataa
    20521 gccactgtgg attagttcat ttcctccaat cgcttgacga tttccgaaag ggtctaacaa
    20581 cagctttttg tttcaattgg taatgagttt gataacgcat agacgtttta tctcgtctaa
    20641 ggtaacaagg caaaaagttc gtggataacc aagtagactt gaaatactat atctggaggt
    20701 actcccatgc tttatgtggg cattgatgtc gctaaaaata aacacgatgt tacagccttg
    20761 aatgttcgag gaaaactgtt cttaaaccac tcactttttc aaataataaa gctggttttg
    20821 aactcttaga tctgtctttt cgacagctca accaagactg tctcatcgct cttaaacttc
    20881 tttctgaccc caatcgtgaa caatttcaac acgataatcg gcaagtagaa ctaaaaatac
    20941 tggctagaca tattcatcgt ctcaagaaaa aacagtctga ttggaaagta caatacactc
    21001 gttgtcttga tatcatcttt cctgagttgg ataaaatcgt tggaaagcat tcagaatata
    21061 cctaccaact cttgacacgc taccctaatc ctcagaaaag gcttgaggca agatttgata
    21121 agctgataga aattaagcga ttgaccgctt ctaaaattca ggatatcctc tcagtcgcac
    21181 ctcgttctat cggaacaaca tctcctgctc gtgaattcga aatcatcgaa atcatcaaac
    21241 attacaagag gctcattgac aaggcggaaa catgtgtcaa tgacttgatg gctgagttca
    21301 actcggtcat cacgacggtt actgggattg ggggtcgttt aggggcggtc attttagccg
    21361 agattcgaaa tattcatgcc tttgataatc ctgctcaatt acaagctttc gctggactgg
    21421 attcttctat ttatcagtca ggtcagattg atttagctgg aagaatgatc aaacggggtt
    21481 cccctcatct gcggtgggca ctcatacaag ctgccaaagc atgcgctcgc ttttcacctg
    21541 cttttaaggc ctatcttaag actaagttag aataaggaaa acattacaat gtagccatca
    21601 tccaccttgc aaaaaaactt atccgaaccc tgttttatat cctaaaaaag agctgccatt
    21661 tgacgaacaa aaagtgatgt aatttctgaa attaacacag gattaccttt gaaaaaatgg
    21721 actttttcaa gggctttttg ccgtgctcta aaatcatcgc caaatcatca aattgaaata
    21781 agaaatagtt tagataaaac tattgacttt tcttatagtt tgtctttctt ctatcttcca
    21841 ttatatcata ctttttcagt ctatggtagc tctctttaaa aggctccgat actgccgcca
    21901 cctccgcctc cagagaagcc accgccagaa cttccacttc cagaagatac ggagtaggta
    21961 cttgctgtat ttgcgacact agcataatgg ctcatttgcg cgcttgaatg ataaaacata
    22021 ctgtgccagc cataagctac atagagattg atatctggat tttcaacttg aatctgatga
    22081 accttcatca aatgactaac cttgtccgca tagccaaata aggttgcata gaccaagaga
    22141 cgattccaaa caacaatact ttccaattca gccttatcca gtcgtgcaat ctcacgtaac
    22201 atattttcaa aactggtcca gagatagtag acctcagctc ccgcttcatt tagaacacca
    22261 tcacgattat ctagtcgaag cttccaataa tagaaaacag acaaaactaa ccctagaaaa
    22321 ccaagtattg gcaaagggag gtaaagatag ccatgaacgt ctaaactgta caagaacaaa
    22381 ccaaatccga taaatagggg caagatagtc aagacaccca tacccacttg caaagccttt
    22441 tccaaaccag ttaaaggacg atagtaatct gggagccccc agaaggaaac tcgttttctc
    22501 actccttctt gcatctggtt caatacctct tcaaaagaag atttgagttg aagccctctt
    22561 gcttgaatcc gtttttcatc agaaactttg gctctacgat aaagactatc agataccttg
    22621 taatccgcaa acaaattgga aagagtttct tcttttttac ctgaaaaagc tagatttagg
    22681 cagtctttct caaagcttga caaaccatct tcttttacta gcctcaaacc aactgcatct
    22741 ccttctgaaa tgatagagac attcccacgg tctatcacat ctagcaaggt agcttgaata
    22801 agttgatcaa aggtgaattt tccagctccc ttgaccaagg gactcacttc ctccaaggag
    22861 gtcgagtaga ctgcttctga taaaaccata ggctctaatt ccattggggg ttcatagaga
    22921 cgatgatttt tagcatattt gattgaagga gcggtctttc ttctatagat aaaatagaaa
    22981 cagatgctca ataacaagga gatggaaagg atcgaaggga agatccaagt aagtagttgt
    23041 ttactttgat ctttttcttt aacgatcgaa tcctctatct tattaaactc ttctaaacga
    23101 ttccctttca agccctgatc cctagcgcta gcaaaatcag ttcgcggcca gtaggcatgc
    23161 aattcaactc cacgcttagc cggaagattg tctaaacgaa tagtataatc aaggttactc
    23221 ttttcaaccg ttctctctct aaaaagtttc cctgtatgga aaaagagttt ctcagccccc
    23281 ttgtctcccc ttacatgaaa ttcaaacttt tcaatagact ctgaactatc tgtcagaggt
    23341 tgccaattta attcagcgat atcatcataa aggaaaagta aattttttaa gttccagacg
    23401 aggtcaactt caactatgtc gccctcctga cctggattat agactctcac agtataacca
    23461 tccgcttctt ctgttacttc gctagtcaca tctgctagtt ctgcaccgtt tttcgcggcc
    23521 tgaatctttg gatgagggtc aatgtcaaac ccgctaggca tcttaccagc acgtccaagt
    23581 cccacgattt ggcccttaaa gtcctcctca aactggtaaa ctatcttctg tctaaactct
    23641 gccgtattgt ctgcatgaat atacaaatcc ccttgataag agtttatctt gaaatcaatg
    23701 gcaaaaacag agagtggaag aaggcaaaac aagcctaaca ccagtaagaa aaaagttttt
    23761 ttcatcaact aagccccctt tttatctttc ttatcattat agcatttttt cgtaagtaaa
    23821 ggcttactta tgttgaaaaa ttacgcattt ttcgataaaa taggagacag ttatttttta
    23881 atagatcaga ataggagaaa tcatgagaaa aatatactta tctattttca caagtctctt
    23941 gctgatgcta ggacttgtca atgttgctca agccgatgaa tatttacgca tcggtatgga
    24001 agcagcatat gctcccttta actggaccca ggatgatgat agcaacggag ctgtcaaaat
    24061 cgatgggacc aatcagtatg ccaacggata cgatgttcaa atcgccaaga aaatcgctaa
    24121 ggacttaggt aaagaacctt tggttgttaa aaccaagtgg gaaggtctag tccctgccct
    24181 tacttctggt aagattgaca tgattatcgc aggtatgagt ccaactgcag aacgcaaaca
    24241 agaaattacc ttttcgagca gttactatac tagcgaacca gttttgcttg tcaaaaaaga
    24301 ttctgcctac gcaagtgcta aatctttgga tgactttaac ggtgcaaaaa tcacttctca
    24361 acaaggggtc tacctttata acttgattgc acaaatccca ggtgctaaaa aagaaacagc
    24421 catgggagac ttcgctcaaa tgcgacaagc tcttgaggct ggtgtcattg atgcttatgt
    24481 ttctgaacgt ccagaagcac tgactgctga agctgcgaac tctaagttca agatgattca
    24541 agtagaacct ggtttcaaaa ctggggaaga agatacagct atcgctattg ggcttcgtaa
    24601 aaatgacaat cgtattagcc aaatcaatgc cagcattgaa accatttcaa aagatgacca
    24661 agttgccttg atggatcgta tgatcaagga acaacctgcc gaagctacaa caactgaaga
    24721 gactagcagt agtttcttta gccaagttgc taaaattctt tctgaaaact ggcaacaact
    24781 cttgcgtggt gctggtatca ctcttttaat ctctatcgtc ggaaccatca taggtctcat
    24841 tattggactt gccattggtg tcttccgtac tgctcctctc tctgaaaaca aagtcattta
    24901 cggcctacaa aaactagtcg gctgggttct caatgtctac attgaaattt tccgtggtac
    24961 gccaatgatt gttcaatcga tggttatcta ctatggaact gcccaagctt tcgggatcaa
    25021 ccttgaccgt acactggctg ctatcttcat cgtttcaatc aataccggtg cctacatgac
    25081 tgaaatcgtc cgtggtggta tcctagcagt tgacaaggga caatttgaag ctgcgactgc
    25141 tcttggtatg acccataacc agaccatgcg taagattgtc ctacctcagg tagtccgtaa
    25201 catcctacct gcaactggta atgaatttgt catcaatatc aaagatacat ctgtattgaa
    25261 cgttatctct gttgtcgaac tttatttctc aggaaatacc gtggcaacac aaacctatca
    25321 atacttccag acatttacaa tcatcgccgt gatttacttt gtcctcacct tcaccgtaac
    25381 acgtatccta cgctttatcg agcgcagaat ggacatggat acctacacta caggtgctaa
    25441 ccaaatgcaa acggaggatt tgaaataatg acacaagcaa tccttgaaat taaacacctc
    25501 aaaaaatcct atggacaaaa cgaagtgcta aaagacattt cactcactgt ccacaaggga
    25561 gaggtcatct ctatcatcgg aagctctgga agcggaaaat cgaccttcct acgctccatt
    25621 aacctacttg aaacaccaac tgatggacaa atcctttatc atggacaaaa cgtcctcgaa
    25681 aaaggctatg acctcacgca ataccgtgaa aagttgggga tggttttcca atcctttaac
    25741 ctctttgaaa atctcaatgt tcttgaaaac acaatcgtcg ctcagacaac tgtcctaaaa
    25801 cgcgaacgca cagaagctga aaagattgcc aaagaaaacc tggaaaaggt cggcatggga
    25861 gaacgctact ggcaagccaa accaaaacaa ctctcaggtg gtcaaaaaca acgtgtggcc
    25921 atcgctcgtg ccctctccat gaatccggac gctattctct ttgatgaacc aacatcagct
    25981 ctcgatccag aaatggttgg agaagtcctc aaaatcatgc aggacctggc tcaggaaggc
    26041 ttgaccatga ttgtcgtaac ccatgaaatg gaatttgccc gtgatgtctc tcaccgtgtt
    26101 atctttatgg ataagggcgt gatcgctgaa gaaggtaaac cagaagacct cttcaccaat
    26161 cctaaagaag accgaacaaa agagttcctt caacgctatc tcaaataaaa agaaaaggct
    26221 gcatcaaccg tgcagtcttt ttgctgtcct caaaatgaaa aggcagattc tctatctcta
    26281 ctacttgaag gtcaagaatt cgccgttatc caaagattaa tcttcaaatt tttcataatt
    26341 tttttcatag aaatcaatta ggcctagggc tgtttcaaat gaaatatttt ttacttttgc
    26401 acgaccctgc gccagagcaa tgatagacat ttcacgcgca ttcgtttctt tagagatacg
    26461 gtagcctgtg attttcttat cacgaaccca gccaacaact gattctactt tttcaaagtt
    26521 tgacttagcc atgtttttct cctattttct tctttataat atttaattgt atacgttttt
    26581 actacttttg tcaataaaaa aaacatatat tcaacgaaaa taattagttc agaattttct
    26641 tacttccttt ttaaatccga taatatatag gttttgctag cctctacacc ataaatattt
    26701 gctaataaaa atactgtatt attaccctct taaggtgcga aattattcaa gttcttaaaa
    26761 aatgcttctc tatttccgta agatagctta tttcttcgat ttaagaactg aagatgatag
    26821 ttctaacctt tagaaatcca agccttcact agctcaaaaa ctcctatctt tcttcctcaa
    26881 taaatcatct gagagatagg tattccttat gtccttaaaa ttcatcactc ctttggatat
    26941 tgaggtgcta gcctagaagc agacacccga ttatctaaac catccttaat agagatgaca
    27001 agacagataa gctcagttaa ttacttatat atctttttaa tatggtatat ttgtcaacaa
    27061 aaagaaatca aatcatacct tatactcaat gaaaatcaaa gagcaaacta ggaagctagc
    27121 cgcaagttgc tcaaaacact gttttgaggt tgcagataga gctaacgtgg tttgaagaga
    27181 ttttcgaaga gtattaaaga cagtgtgact atgcttgtca atagatagga aatcaaaatg
    27241 aaggatggaa atctgagcca aacatcataa gtgctataat gaacagaagt aagaattgca
    27301 cgataagttt tctaaaacca taggaatcgt cccctttctt catcttcatt atagcacata
    27361 tacatcagtt gtacaaataa tatgatattt ttttattagt cctcagacaa gcatattata
    27421 aagcgtttca ttaccattta agttaatata agctggatca aaaccttcca ttctacgaat
    27481 caaacctgca taatcatgct tatctgctaa agcgatccca attaatactg ggcctgttcc
    27541 cttgctagct cgtttgatat actcaaaacg tgtgatatca tcatttggcc ccaggatatc
    27601 atttacaaac tcacgcaaag ctcctggacg ttgtgggaaa ttgaccacaa agtaatgttt
    27661 gataccatca taaatcaagg cacgctcttc catttctggc atacggttga tatcattatt
    27721 tcctccagaa atgatacaac aaatggtttt ccccttaata tattcagcta aaacctctaa
    27781 agaggcgata ctagccgctc cagcaggttc tgcgactatc ccttgcttag agtaaaggtc
    27841 aatcaaggtt tcagaaatca atccctcatc gacacctacc aaagttttaa tatgttgacg
    27901 agttgcttca taggtcaact gacctacctt ttgcacagca atcccatcag caaatttatc
    27961 aatttccttg agtttgactg gacctccagc ctcaaaggca gctttcatgg aacgcgctcc
    28021 attcgcctct actccgataa cctcaatctc tggacttgtt tccttgatat aggtagaaac
    28081 cccggcaatg agaccgccac caccaacagg aaccaagaca gcatcaaaat caatcgattc
    28141 ttttcgagct tcttctaaaa tctcataagc aactgttcct tgacctgctt gaacatgagc
    28201 atcatcaaaa ggatcaataa aggtacgatt ttcagagact gtaaattctt gagctgcttt
    28261 ggctgaggca tcaaaggtat ctccaactag tttaatagtt acaaaatccc caccaaaaaa
    28321 gcgaacctga ccaatctttt gttgtggcgt agtaatgggc ataaagatag tagcaggaat
    28381 tttcatttca ttacaagtat aggctactcc ctgcgcatga tttcccgcag aagcgcagac
    28441 taccccacgt tcacgttctt ccttgctgag ctgggaaatg gcataatagg caccacgaat
    28501 tttaaaggag cgaacacgct gggcattttc ttttttcaaa taaatcttag caccatactt
    28561 ctccgataaa taatgatcgt aatccagtgg agtattcaca accacaccgt tcaagacctt
    28621 gtgagccttg attatatctt ttgaacttaa catataaaac ctctttttct ataaaaaaca
    28681 gtcactaatg actgtttttt agttattcat ctccgaaaac ttcagtaaca ctttcatggt
    28741 atttatgagc catacgaatc gaaaactctt taggaagttc ataacgattt gtggaaatcc
    28801 aatcatataa ccattctacc aaactttctt cactatcatt acgatggaag ataaaatagt
    28861 ttaaaatttc tttatattct acatcattca aatccaacgt gtctacaaat tgactacgag
    28921 gaacaaaatt agaatctaat tttcttagtt gatctgtcaa ttctcccaat tgtaaatcca
    28981 actgaaaaaa tagtttttgc agttgcctat cagtttcatc acatcctgtc ttgatagaaa
    29041 acaaattggt aatattcata tgatttcaac ccctaaataa gtacatctaa tatcccacga
    29101 atagctgaag ctaaagtttt cgcagtccag tcatttaaac ccgattcttt caatccagat
    29161 gcaataattt gctctatttg atataaatcg ccatctatcg tctcatttat tctgcgaaga
    29221 ggaccttcaa tataggataa agcttctccg aatctaacag ctgatttagg tcctaatgat
    29281 ttaccaacta tatttgttaa tgttttttat ttctcaaaat ccatttcgct atataacgag
    29341 cagatttagt cgcatcagct ctctcaaacg gagaatgaat ttcaagacct tcttctctag
    29401 ctatttgtgc caatttgaag aattgttcaa aggtcatatg caacctacca tcttcaaaat
    29461 tagcatcatc ataaatgtta attacagcat tttcatcata cgaccaatct gctttatttt
    29521 ggtctgctag cactattacc gacggtgtaa ttacattata caactagaac caataataac
    29581 gatgcaattt ttctcataat ctttttcata aaatcatctc cagcgctata tatttctaat
    29641 tagttataga ttttgaatgc atcatcgtcg tttttaccaa cgaatggcat tgctttacgc
    29701 aattctgcac caactttttc aatttcaagg ttagctgctt gttcacggta agcagtcaat
    29761 tttggacgtc cagctttata gtcatttaca aagtcatttg caaacttacc attttggatg
    29821 tctgccaaga cagccttcat attttcttta acttgttcag tgattacacg tggacctgat
    29881 acatagtcac cgtattcagc agtgtttgaa atagactgac gcattttctt gaatccacct
    29941 tcgtagatca agtcaacgat caatttcatt tcgtgaagaa cttcaaagta agccaattct
    30001 ggagcgtaac ctgcttctgt caagacttcg aaacctgctt cgataagggc agtcaaacca
    30061 ccacaaagta cagcttgttc accaaacaaa tcttcttcag tttcttcttt gtaagttgtt
    30121 tcaagaagac ctacacgagc cgctccaaca cctttacacc agtccatagc aatgttttta
    30181 gcatttcctg ttgcatcttg gtatactgca taaagagctg gaacaccaaa tccttcttcg
    30241 taagtacgac gtaccaagtg tcctggtcct ttaggagcac acatgaagac atctacatcc
    30301 gcaggaactt tgataaattc aaagtggatg ttgaaaccat gggcaaatcc aactgcgttt
    30361 ccagcttcca agtttggagc gatttctgct tcgtacaatt cttgttgaat ttcgtctggc
    30421 gccaagatca tgataacatc agccaactta gtagcttctg ctactgtgta agtatcaaat
    30481 ccatcttctt ttgctttatc aaaagattta cctggacgta caccgataat aacgtcacga
    30541 ccggaatcac gcaagttttg agcatgcgca tgcccttgtg aaccataacc gataacggcg
    30601 atttttttac cgtcaagtgc tgctacttta acatcttttt catattccat ttgaactgtc
    30661 atagcttttc tctcttttct attatttatt gccttttagg ctggtttaat aaatttaagt
    30721 tggattttta atcgcgggta aatccagttg cacccgttcg agcaatattg cgaataccgt
    30781 atgggcgaat gactcgcaat agggcttcgc tcttttctgc atttcccgtc atctgaatgg
    30841 taatcgagct tggcgctacg tctaccactg ttgcacggaa aggttgaata atcgctaaaa
    30901 tctcagctct cttctcagct ggcgctgaca tcttaaccaa aatcacctcg cgctccaaat
    30961 gaggcttgtc tgtaatatct cgaatgcgaa tcacatcaat ctgacgattg agctgtttga
    31021 tgatttgctc cacttcatca tgagaagcaa catcaataat aatagtgata cgcgatacat
    31081 tcggatcttc tgttgctcca acagagatgc tttcaatatt aacctgacga cgagatagga
    31141 cacctgtaaa gcgattgagt actcctgaac gattttgtag ttttgctgtt aacattctac
    31201 gcatggaact tcacccccaa catctcatga ttactcttac cagccggtac cattggtaac
    31261 acctgttcct tacgagaaat atctacctca attagcatag gaacatcctc agtgatgact
    31321 tcaaggtctt gagccaaggt ctcaggattg tcaaacttat agtttttaat accataagcc
    31381 tgcgccatca attggaaatc aggaagggta tcaaagaccg actctgatgt tctgccttca
    31441 tagaaggatt cctgccactg gcgaaccatt ccaagtgaat gattgttcag cataaccacc
    31501 ttgattggca ccttgtaaat attcaaaata gccaactcct ggttggtcat ttggaaacca
    31561 ccatccccaa caaacaagac tacttcctta tctgggttag caattttagc accgattgct
    31621 gctggaattc caaagcccat tgttcccaaa ccacctgaag tcactaactg acgctcattt
    31681 tggtagggat aatactgagc tgtccacatt tggtgttgac caacgtctgt taccacaatg
    31741 gcatctccat tcgtcaattc accaattcgt tcaataactg cttgcggttg aaccacacgc
    31801 tctttcttgt cataagaacg aacacgattc ttgtctttag tgactttctc aatccacttt
    31861 tcagtattgt tgtgaactgt tggttctgct agcaacattt gcaaggcctt cttagcatct
    31921 ccaactacag gaatgtctgc actgataatc ttgccaatct cagctgggtc aatatcaatg
    31981 tgggcaacct tagcattctt agcgaaagtc ttaggattcc ccgtcaaacg gtcatcgaaa
    32041 cgagaaccaa tactaatcat aaagtccgct tccgtcatgg caatatttgc tgcgaatgac
    32101 ccgtgcatgc ctcccattcc aagaaagagt gggtgactcg ttgcaatcgt tccttgtccc
    32161 aaaagactgg ttaccactgg aatttgatag cgttctgcaa attcatttag ttccgtagca
    32221 gcctcagcat aactaattcc accaccagct aacaagactg gctttttagc cttggacaat
    32281 tgcttcaaga ttttcttgat ttgcatatca ttcggctcaa gagtcggctg ataacttggt
    32341 aaattcactt ctggtgaata aatgaagtct gtttctaaag cagatatgtc ttttggtagg
    32401 tcaattacaa ctggccctgg acggcctgta gttgcgatat ggacagcttc cgtaatgata
    32461 cgcggaatat cagctgtctc acgaacttgg taattgtact tagtgattgg catggtaatt
    32521 cccacgatgt ctgcctcctg aaaggcatcc ttcccaatcc ctgctcgcgc cacctgacct
    32581 gtaaagacca aaaggggaac gctatcgctc atggcatccg caatccctgt aatggcattt
    32641 gttgctcctg gtccactagt gacgacggca acacccaact ttccagttga tttggcataa
    32701 ccttcagctt catgcaaaca accttgctca tggcgcccta gaatgtggcg aatgccttta
    32761 aaattatata tcgcatcata aaaaggcaaa accgcaccac caggataacc aaagatggta
    32821 tcaactccta aatcacgaag tgtttccaaa actaggtccg accccgtctt aggagattct
    32881 aaactgattt tctccattat tcccctttct ttcctcttaa aaataacttg ttactatcat
    32941 accatttttt caaaattttt caagataaaa gaagaaattt tctgaatttt ctattttaac
    33001 gtttatttat gaatgttatt tttgttttta ttaaaaagat accgatttca tttactaaaa
    33061 aagaaaaaag aactgatttc tcagtccttc attaatctta ttccacacta aataggtatg
    33121 ggtaaacagg ttgttgacct tggtgaatct cgacttcaac gtcttcgaat tcttctacga
    33181 tttcttgagc gatttcattg gcaagttctt cgcttccgtc ttcaccgaca tagaaggtta
    33241 cgatttcact gtcttcatcc aacatatgtt tcaaggtttc agtcaatgtt tggtgcatat
    33301 cagggtttga cacaagaatt tttccatcca ccatacctag attatcgttt tcatggattt
    33361 ctaagccatc gatcgttgta tcacgcacgg ctgttgtgac gcttccgcta acaacatcgc
    33421 taagagcagc tgtcatacgc tcttggtttt cttcaatgga cttgcttgga tcaaaggcaa
    33481 gaagacttgt cataccttga ggaagagtgc gagcctctac cactactgct ggttgctcca
    33541 aaacttctgc cgcagattga gctgccatga agatgttctt gttgtttggc aagaagatga
    33601 tgttacgggc attgacctgt tcaacagcct tgataaagtc ttctgttgaa gggttcatgg
    33661 tttgaccgcc ttcgataaca taatccacgc cttgagaaca gaagatatct gctagacctt
    33721 taccagccac cacagcaatc aaagcatact ctttttcttc agccgacttg ataacttgag
    33781 tagcttcttt ctcaacctgt gcttcgtgtt ggttacgcat attgtcaact tttaccttga
    33841 ccaagctacc atatttgaga ccttcttgca taacaagtcc tggatcttct gtatgaacat
    33901 ggactttgac aatttcatca tcgttaacaa cgaggagaga atccccaagc tcatccaagt
    33961 agttacggaa ttcatcgtag tcaaaatctt tagcataggt tggaccttgc ttaagagcta
    34021 ccatgatttc agtacagtaa ccaaacgtga tgtcctcagt cgctacgtga ccagctacag
    34081 acttatgatg ctctacattg atcatctcac tcatgttggc aggagtcgct acaaagtcct
    34141 cagatgcaat atattcgcca gtaagggctg aaaggaaacc ttcgtagatg aagaccaatc
    34201 cttgaccacc tgagtccaca acgccaactt ctttcaatac tggaagcatg tctggtgttt
    34261 tagctagagc tgttttagca ccttccaagg ctgcgcgcat gacttcaaca gcgtcatctg
    34321 tttgctcagc ttttttctta gcaccgatag cagctccacg agaaactgtt aaaatcgttc
    34381 cttcaacagg tttcatcact gccttatagg caacttccac acctgattgg aaggccagag
    34441 ccaagtcttg acctgttaac tcgtctttat ccttgatagc ttgggaaaat ccacggaaaa
    34501 gctgagacgt aatcactcct gagttcccac gcgcacccat caaaagccct ttggcaagaa
    34561 tgctcgctac ttctccaact gtagaagctg gcttgtctgc aacttcttta gcaccatttt
    34621 caatggtcat tcccatattt gtcccagtat ctccatctgg gactggaaag acgtttaatg
    34681 aattgacata ttcagcttgc ttattcaagc gagttgatgc agcctgcacc atttcttgaa
    34741 ataagctagt agtaattttt gacacggtta ttctcctaca actttgatat tttgaatgta
    34801 gacatttaca gtctgagcag taattccaag ctggttttcc aagctaaagg caacacgctc
    34861 ttgaatgttt tttgacactt cactaatctt tgttccgtag cttaacacgg tatatacatc
    34921 aactgcaata ctgccatctt cggctgcctt tacgacgaca cctttagaat aattttcctt
    34981 acctagcagg gcttggaaat tatctttgag ggcattttta ctagccatac cgaccacacc
    35041 aaaaatctca gttgctgctc cacctacgac ggttgcaatc acttcatctg ttagttcgat
    35101 ttgaccatct tttgtattaa tttttacagt catccttttt acctcaacta gttgatactc
    35161 tattttatca tatttcagcc caagtgtaaa agcagaatga tgtatcagcg gatatttact
    35221 ctatttttca aacgatgtta tacccacaat aaaagaaaaa agaccctaag gtctcctttg
    35281 cttttattat taaacgcgtt caactttacc tgatttcaaa gcacgagctg aagcccaaac
    35341 ttttttaggt ttaccatcga taagaacagt aactttttga aggtttggtt ttacggcacg
    35401 ttttgtttgg ttcatcgcgt gtgaacggtt gtttcctgat acagtcttac gacctgtaaa
    35461 gtaacatact ttagccattg tgttttcctc ctattagatc taatatagcg gatgtgctag
    35521 caccacatac cgtactatgt tatcacactt tcttgttttt tgcaagggaa ttggaagatt
    35581 ttttatttgt gtcttaaatc aggtcttgcg tgacattttc tgctctccac atgccattgt
    35641 tgattaacag aacaccagaa ttaaaattat gtgtataaaa atcatctcta actgcagcta
    35701 agggtatagc cgtcaagtcc aaatcccaca gctcatctat cgattttctt acaacaatat
    35761 ctgaatccaa atacagtaca cgagactcgc ttacatactt tggaataaaa tacctaaaaa
    35821 aagccgcata tgaaagtccc tcaaagggga gacgataacc tttcagaata ctactgtcaa
    35881 tctgaacatt cacaatctca ctattcaaag tctctagtct tttttccatc aattggaacc
    35941 attctcacgg aaggtcatca ttaaaaacat aaaacttaag attataatga tgaacacaaa
    36001 gagattttat tgttgtttca actttatcca tataagcatt atctgcacct aagacaatcg
    36061 cttttttctc ttctttcact ctttatctta tttcttttta ttcccatcat attattccca
    36121 tcatatgttt ctacgtaacc attattttcg cctattcgtt cgtaaaacca taccagtgga
    36181 gattttagat gaagtcccat tacggtttac attttttaca ttacgacacg gagttttaca
    36241 aatcgatttc atttgccaaa cgtagttagt gaggcagtta gctagttcgc caaatagcga
    36301 ctagcgtcca acaatttgga actttagttc caattgttgg tactgagtca catcttctcc
    36361 tctaactcta cgtctggata cttgtccgca aaccagcgga gggcaaagtc attttcaaag
    36421 agaaagactg gttggtcaaa acggtctttg gctaagatat tgcgacttga cgacatccgt
    36481 tcatccaagt cctcaggctt gatccaacga acggtctttt tacccattgg gttcataact
    36541 acttccgcat tgtactcgct ttccatgcgg tgtttaaaga cttcaaactg gagttgacct
    36601 acagcgccta gcatgtactc acctgtttgg taattcttat aaagctgaac ggctccttct
    36661 tgcaccaatt gctcaatccc cttgtggaag gatttttgct tcataacatt cttagcagaa
    36721 actttcatga aaatttcagg agtaaaggtt ggcagtggtt caaattcaaa cttgtttttt
    36781 ccaaccgtca aggtatcccc aacctgataa gtaccggtat cgtaaacccc gataatatca
    36841 cctgccacgg cattggtcac attctcacga ctctccgcca taaactgggt aacattagat
    36901 agtttggcac ccttaccagt acgagggaga ttgacactca tgccacgctc aaattcgcct
    36961 gatacgatac ggacaaaggc aatacggtca cggtgacgag gatccatgtt ggcttggatt
    37021 ttaaagacaa agcctgagaa atccttgtca taaggatcca caatttcacc gtctgttttc
    37081 ttgtgaccat gtggttctgg agcaaacttg aggaagattt caaggaaggt ctgcacacca
    37141 aagtttgtca gggctgaacc gaaaaagaca ggcgtcaatt ctccagccag aatagcttcc
    37201 tctgaaaact cattcccagc ttcatttaaa agctcaatgt catccttgac ttgctcgtag
    37261 aaaggattgc taccaaaaag tttgtctcca tcttctaggc tagcaaaacg ctcatcccct
    37321 ttgtaaagct ctaaacgttg gttatagagg tcatacaagc cctcaaaggc tttccccatc
    37381 ccgataggcc agttcatagg gtagctagca atgcccaaga tttcttccaa ttcttgcaag
    37441 agatccaaag gctcacgacc gtcacgatcc aacttgttca taaaggtaaa gactggaatg
    37501 ccacgatgtt tcacaacctc aaacaatttc tttgtttgag cctcgatccc cttggcagag
    37561 tccacgacca tgaccgcagc atccaccgcc atcaaggtac gataggtatc ttctgagaag
    37621 tcctcgtgcc ctggcgtgtc taagatattc acgcgcttgc cgtcgtagtc aaattgcata
    37681 acagatgaag taacagaaat cccacgttgc ttctcgatat ccatccagtc agatttagca
    37741 aaagtccctg ttttcttccc ttttaccgta ccagcatcac gaatctcacc cccaaagtag
    37801 agtaactgct cagtgatggt tgttttcccc gcgtccgggt gggagataat ggcaaaggta
    37861 cgacgtttct taatttcttc ttgaatattc ataagttctc tttctttgat tctctatttt
    37921 tcttgtttca atagctgaga atgattttta cattggattt taccattcct ttcgacactc
    37981 cattatatcg gattttagca tttttttcaa tttctatttc ttttcacttc cccctccctt
    38041 atttatagga aaatatggta aaatagaaca gactaaaaat catcatttca cgaaaggatg
    38101 caagatgaaa attacgcaag aagaggtaac acacgttgcc aatctttcaa aattaagatt
    38161 ctctgaaaaa gaaactgctg cctttgcgac caccttgtct aagattgttg acatggttga
    38221 attgctgggc gaagttgaca caactggtgt cgcacctact acgactatgg ctgaccgcaa
    38281 gactgtactc cgccctgatg tggccgaaga aggaacagac cgtgatcgct tgtttaaaaa
    38341 cgtacctgaa caagacaact actatatcaa ggtgccagct atcctagacg atggaggaga
    38401 tgcctaatga cttttaacaa taaaactatt gaagagttgc acaatctcct tgtctctaag
    38461 gaaatttctg caacagaatt gacccaagca acacttgaaa atatcaagtc tcgtgaggaa
    38521 gccctcaatt catttgtcac catcgctgag gagcaagctc ttgttcaagc taaagccatt
    38581 gatgaagctg gaattgatgc tgacaatgtc ctttcaggaa ttccacttgc tgttaaggat
    38641 aacatctcta cagacggtat tctcacaact gctgcctcaa aaatgctcta caactatgag
    38701 ccaatctttg atgcgacagc tgttgccaat gcaaaaacca aaggcatgat tgtcgttgga
    38761 aagaccaaca tggacgaatt tgctatgggt ggttcaggtg aaacttcaca ctacggagca
    38821 actaaaaacg cttgggacca cagcaaggtt cctggtgggt catcaagtgg ttctgccgca
    38881 gctgtagcct caggacaagt tcgcttgtca cttggttctg atactggtgg ttccatccgc
    38941 caacctgctg ccttcaacgg aatcgttggt ctcaaaccaa cctacggaac agtttcacgt
    39001 ttcggtctca ttgcctttgg tagctcatta gaccagattg gaccttttgc tcctactgtt
    39061 aaggaaaatg ccctcttgct caacgctatt gccagcgaag atgctaaaga ctctacttct
    39121 gctcctgtcc gcatcgccga ctttacttca aaaatcggcc aagacatcaa gggtatgaaa
    39181 atcgctttgc ctaaggaata cctcggtgaa ggaattaacc cagaggttaa ggaaaccatt
    39241 ctaaatgccg ctaaacactt tgaaaaattg ggtgctattg tcgaagaagt cagccttcct
    39301 cactctaaat acggagttgc cgtatactac atcatcgctt catcagaagc ttcatcaaac
    39361 ttgcaacgct tcgacggtat ccgttacggc tatcgcgcag aagatgcaac caaccttgat
    39421 gaaatctatg taaacagccg aagccaaggt tttggtgaag aagtgaagcg ccgtatcatg
    39481 ctgggtactt tcagtctttc atcaggttac tacgatgcct actataagaa ggctggacag
    39541 gtccgtacac ttatcattca agatttcgaa aaagtcttcg cggattacga tttgattttg
    39601 ggtccaactg ctccaagtgt tgcctatgac ttggattctc tcaaccatga cccagttgcc
    39661 atgtacttag ccgacctatt gaccatacct gtaaacttgg caggactgcc tggaatttcg
    39721 attcctgctg gattctctca aggtctacct gtcggactcc aattgattgg tcccaagtac
    39781 tctgaggaaa ccatttacca agctgctgct gcttttgaag caacaacaga ctaccacaaa
    39841 caacaacccg tgatttttgg aggtgacaac taatgaactt tgaaacagtc atcggacttg
    39901 aagtccacgt agagctcaac accaattcaa aaatcttctc acctacttct gcccactttg
    39961 gaaatgacca aaatgccaac actaacgtga ttgactggtc tttcccagga gttctaccag
    40021 ttctcaataa aggggttgtt gatgccggta tcaaggctgc tcttgccctc aacatggaca
    40081 tccacaaaaa gatgcacttt gaccgcaaga actacttcta tcctgataac cccaaagcct
    40141 accaaatttc tcaatttgat gaaccaatcg gatataatgg ctggattgaa gtcaaactag
    40201 aagacggtac gaccaagaaa atcggtatcg aacgtgccca cctagaggaa gacgctggta
    40261 aaaacaccca tggtacagat ggctactctt atgttgacct caaccgccaa ggggttccct
    40321 tgattgagat tgtatctgag gcagatatgc gttctcctga agaagcctat gcttatctga
    40381 cagccctcaa ggaagttatc cagtacgctg gcatttctga cgttaagatg gaggaaggtt
    40441 cgatgcgtgt ggatgccaac atctcccttc gtccttatgg tcaagagaaa ttcggtacca
    40501 agactgaatt gaagaacctc aactccttct caaacgttcg caaggggctt gaatacgaaa
    40561 tccaacgtca agctgaaata cttcgctcag gtggtcaaat tcgccaagaa acacgccgtt
    40621 acgatgaagc taacaaaaca accatcctca tgcgtgtcaa ggaaggggct gcagactacc
    40681 gctacttccc agaaccagac ctacccctct ttgaaatttc tgacgagtgg attgaggaaa
    40741 tgcggactga gttgccagag tttccaaaag aacgtcgtgc gcgttatgta tctgaccttg
    40801 gtttatcaga ctacgatgct aatcagttga ctgctaataa agtcacttct gacttctttg
    40861 aaaaagctgt tgccctaggt ggtgatgcca aacaagtctc taactggctc caaggggaag
    40921 tcgctcagtt cttgaatgct gaaggtaaaa cactggaaca aatcgaattg acaccagaaa
    40981 acttggttga aatgattacc atcatcgaag acggtactat ttcatctaag attgccaaga
    41041 aagtctttgt ccatctagct aaaaatggcg gtggcgcgcg tgaatacgtg gaaaaagcag
    41101 gtatggttca aatttcagat ccagctatct tgatcccaat catccaccaa gtctttgccg
    41161 ataacgaagc tgctgttgcc gacttcaagt caggcaaacg taacgccgac aaggccttta
    41221 caggattcct tatgaaggca accaaaggcc aagccaaccc acaagttgcc cttaaactac
    41281 ttgcacagga attggcgaag ttgaaagaaa actagacaga acaaaaccag ccctaaggtt
    41341 ggttttttct tgacaaatag aaagaaaacg tttacaatat tgcgtgtaaa gtttccaaac
    41401 aagaaaacta aaaatcgcaa caataaggag ttatttatat ggctacaatg aaggcagctc
    41461 gctggcatgc agcgaaagat gttcgtattc aagaaataga agttcctgaa gtacttccgc
    41521 accaagtaaa agttgcagtt aagttcacag gaatttgtgg tactgacctc catgaatttt
    41581 tagatggacc tatctttatc ccaacagatg agcacgtcta ttctggtcaa aaagcaccgg
    41641 taacactggg acatgaattt tctggtgaaa tcatagaagt cggaagcgat gttacccgtg
    41701 ttaaagttgg tgatcgtgtt gctgtggaac caattctagc taaaaataac ttagttggtg
    41761 attataattt ggatccaaac cttaattttg tcggtttggc tgcagacggt ggatttgcca
    41821 aatattgtgt tttagacggt gacttagtac atgtcattcc agatagcttg agctatgaac
    41881 aagctgctct tactgaaccc gctgctgttg cagtctatgc tgttcgtcaa tcttctttga
    41941 aggctggcga tacagctgtt gtctttggtt taggcccgat tggtctatta attgtagaag
    42001 ctcttcgtgc agctggtgct tctaagattt atgctgttga actatcacct gaacgtcaag
    42061 caaaagctga agagttagga gctatcgttg tccgtccgga agaaggtgaa acagctgttg
    42121 aagctattca tcgtttaaca aacggtggtg tagatgtttc ttatgaagta acgggtgtgc
    42181 cagtagtttt aggacaagcc ttagctgccg tacataaagc aggtgagtgc atggtggtct
    42241 ctatctggga acgagaagca aatattaatc cgaatgaatt tgcaatccaa gaaaagacac
    42301 taaaaggaat catcgcttat cgtcatatct tccctaaagt attagaattg atggaacaag
    42361 gctacttctc tgctgaaaaa ttagttacta agaaaattaa attggaaaat atcgtcgaag
    42421 aaggctttat cgaattaact caagataagt cacaaattaa aattttggta gaaccagaat
    42481 aaaaaatcaa tctttttaag acaatactaa caggtcggag taaacttact tcggcctttt
    42541 gaaatataat actcttcgaa aatctcttca aaccacgtca gcgtcacatt accgtatata
    42601 tggttactga cttcgtcagt tctatccaca acctcaaaac agtgttttga gcagcctgcg
    42661 gctagcttcc tagtttgctc tttgatttcc attgagtatg agaagaaata tagtggatac
    42721 tctttaacat taaccactcc acctgactag ccaatattct ttttcgctcc taccaactcc
    42781 caataactat tttggcttta tttccagagt attttatggt aaaatgaaga gtaataatat
    42841 ttgttaaaga ggtaaaaaca tgattgaagc aagtaaatta aaagctggta tgacctttga
    42901 aacagctgac ggcaaattga ttcgcgtttt ggaagctagt caccacaaac caggtaaagg
    42961 aaacacgatc atgcgtatga aattgcgtga tgtccgtact ggttctacat ttgacacaag
    43021 ctaccgtcca gaggaaaaat ttgaacaagc tattatcgag actgtcccag ctcaatactt
    43081 gtacaaaatg gatgacacag catacttcat gaatacagaa acttacgacc agtacgaaat
    43141 ccctgtagtc aatgttgaaa acgaattgct ttacatcctt gaaaactctg atgtgaaaat
    43201 ccaattctac ggaactgaag tgatcggtgt caccgttcct actactgttg agttgacagt
    43261 tgctgaaact caaccatcta tcaaaggtgc tactgttaca ggttctggta aaccagcaac
    43321 gatggaaact ggacttgtcg taaacgttcc agacttcatc gaagcaggac aaaaactcgt
    43381 tatcaacact gcagaaggaa cttacgtttc tcgtgcctaa tctctagaaa gaggtcattc
    43441 tatgggaatt gaagaacaac ttggcgaaat cgttatcgcc ccacgtgtac ttgaaaaaat
    43501 cattgctatc gctactgcaa aggtagaggg tgttcactct ttttcaaaca gatcagtgtc
    43561 tgataccctt tcaaaacttt cactcggccg tggcatttat cttaaaaacg tggacgaaga
    43621 actcacagca gatatctatc tctaccttga gtacggagta aaagttccta aggtagcggt
    43681 tgctatccag aaagctgtca aagatgccgt ccgtaatatg gctgatgtag aactcgctgc
    43741 tatcaatatt cacgttgcag gtatcgtccc agataaaaca ccaaaaccag aattgaaaga
    43801 tctatttgac gaggacttcc tcaatgacta gtccactatt agaatctaga cgccaactcc
    43861 gtaaatgcgc ttttcaagct ctcatgagcc ttgagttcgg tacggatgtc gaaactgctt
    43921 gtcgtttcgc ctatactcat gatcgtgaag atacggatgt acaacttcca gcctttttga
    43981 tagacctcgt ttctggtgtt caagctaaaa aggaagaact agataagcaa atcactcagc
    44041 atttaaaagc aggttggacc attgaacgct taacgctcgt ggagagaaac ctccttcgct
    44101 tgggagtctt tgaaatcact tcatttgaca ctcctcagct ggttgctgtt aatgaagcta
    44161 tcgagcttgc aaaggacttc tccgatcaaa aatctgcccg ttttatcaat ggactgctca
    44221 gccagtttgt aacagaagaa caataaaaag aaaaagtgtt tgatagatat caaacacttt
    44281 tttctttgcc tcccactatc taaaaaaatg ataatagata taattgtaaa caaaaatcca
    44341 gataggtttt gcatgattga gaaagttaaa aaaactatgg cagagaatcg ttaatctcag
    44401 attgtcggta gaacgataaa caagggcaaa aaagaaacca atcagactat aatataataa
    44461 actaattgga tctctgtgag atagtatcaa atggctaatc ccaaagatga tagcagatag
    44521 gataacatcc aaatagtact tggactaggg aaagaaggta ttcataaaat accctctatc
    44581 aagagtctcc tcaaaaacag gaccgatgat tacaggcagg acaaaagata agatagtcga
    44641 taaaaaggtt ggttgtccat ttgaaaaaag cacggtaaaa tactcatcat gaatattcct
    44701 atgattaatc aaatgagcat agcgtgccca aaaattaccg agaatctgat aaaccacata
    44761 agttgcaaat aagtagaaga caaatgacca gttccagctc tttttctcaa agataaagag
    44821 catctttttc ttttttaacc tccaaattaa tagaaggaaa cttcccacta atcccattgt
    44881 taaaataaga gaatagacat cagctcctaa ccctaaaatg atcgtcacat acaatccaat
    44941 tgtttgtggt aaataggtag atagtaaaat aataagcaaa aatattccaa attgtcttag
    45001 tttttttgtg tttctcatcg tacttttttg aaagattacc ctgctcggaa gccgtacttc
    45061 caagcatcta tataagaatt aagtgcccct tgcctcatat agggagcaaa ttctctataa
    45121 tataaccatc tactatatcc atcttcccaa acagcaagac cacctgaagt ttgctccaag
    45181 tcctcagttg aaagaactgt aaatgtattt gtacctgtca ttgcaagtac cttcttaaaa
    45241 tagattgttg taggctcaca tttatagtat atttcttttt ttgtctattt tatagcccat
    45301 ctcctcaact ggcaattttt cgacctgaat tacatttttc cataaaaaat gagacctttc
    45361 tagtctcatt tagtcattct tagtattttc taaatcgttg atagcgttct tccagcaact
    45421 cttctagcgg tttttgtgaa agtctagcca gctctgtttg gagttctttt ttgacactct
    45481 taatcagttc tttactagaa agtcctattt cagaaatcac cttatctacc acgtccattt
    45541 ctaacagttc atgcgaagtg attttcatca gttctgctgc ttccatagcg cgagtaccgt
    45601 ccttccataa aatggaagca aagccttctg gactgagaat ggcatagata gaattttcca
    45661 gcatccagac acggtccgcg acagctagag ccagagcccc gcctgaacca ccttcaccga
    45721 taataatggc gataatagga actttcaggt cactcatttc catgagattg cgagcgatag
    45781 cttccccttg accacgttct tccgctccga caccaggata agcacctgct gtattgataa
    45841 aggtcacaac tggacggcca aatttctcag cctgtttcat caaccgcagt gcctttcggt
    45901 agccttctgg atgtggttgg ccaaaattcc gtttgaggtt gtcttgcaaa ctcttgcctt
    45961 tttggatacc aaccactgtt acagcttgat ctccaagcca accaatacca ccaacaactg
    46021 caccatcatc acgaaaagaa cggtcaccat gtaattggat aaattcatca aaaatgcctg
    46081 tcgcaaagtc caaggttgtc aagcgactct gctcacgcgc ttctctgact atttttgcaa
    46141 tattcatcta ggactccctc catgcaatct gactaggcta gcaatcgtat ctggtaagtc
    46201 tcttcttttg acaatagcat ccacaaagcc atgttctaat aggaattctg ccttttggaa
    46261 atcctcaggc aagctttcac gaaccgtatt ttcaatcaca cgacgcccag caaaaccaac
    46321 caagctctgt ggttcagcca gaatgatatc gccttccata gcgaaagaag ctgtcacacc
    46381 accagtcgtt ggatctgtca aaatggtcag gtaaaagaga ccaacatttg aatggcgttt
    46441 aaccgccgca gagatcttag ccatctgcat gagactcatg attccttcct gcatacgggc
    46501 tccaccagag gctgtgaata ggacaactgg caatttttcg acagtcgcat actcaaacaa
    46561 acgagtgatt ttttcaccta caaccgtacc catagaagcc atgataaagt tagaatccat
    46621 aatcccaaga gccacagtct gacctttaat aagagcagtt cctgtcacaa cggcttcatg
    46681 cagacctgtt ttttcacgca tagatgccag tttcttttgg taaccaggga aatgcaaggg
    46741 atccttgctt tcaatccctg taaacaattc tttgaaggtt cccatatcaa tcgtcaaagc
    46801 caagcgttct tgggcagaaa tacgaaaggt atagctacag tgcggacaga tacgttcact
    46861 tcccagatcc ttctgataga tggtatgctt acagcctgga cactgggaaa ataattcatc
    46921 tggaacctct ggcttagctt gaggtttttc cctaaccgaa cgattgggat tgattcgaat
    46981 atacttatct tttttactaa atagagccat tgattcccct tttcggttta aactcttaaa
    47041 gtcattttat tctttttctt gatatttagg taagaaggtt tccatcaaga aggaagtatc
    47101 ataatcccca gcaatgacat tgcgatctga aatgaggtca agctggaaat ctgcattggt
    47161 ctgcactcct tcaatctcta attcatagag ggcacgttgc attttcatca aggcgtcaaa
    47221 acgattttcg ccgtgtacta tgattttggc aatcatacta tcataataag gcggaatggt
    47281 ataacctgga taaactgctg aatccacgcg caaaccaact ccaccacttg gcagatagag
    47341 attagtaatc ttacctggac ttggagcaaa gttaaaggct gggttttctg cattgatacg
    47401 acactcgatg gcatgaccac gtaggacaat atcttcttgc ttaacagaca aaggctgacc
    47461 tgccgcaatg caaatctgtt ccttaacgat atcaacacct gaaacaaact ctgttactgg
    47521 atgttctacc tgaacacgag tattcatctc catgaaatag aaattgctac ttgcttcatc
    47581 aagaagaaat tcaatggttc ctgcattctc atagccaaca aactctgccg ctcgaacagc
    47641 agcagcacct atttcatgac gcagcgtttt tccgattgca atcgagggac tttcttccaa
    47701 aaccttttgg ttattccttt gaagagaaca atcccgttca cccaagtgaa tcacatgtcc
    47761 atgctcatca cctaggattt gaacctcaat gtgccgagct ggatagataa cccgttctat
    47821 gtacatggca ccattgccat aattggcctt ggcctcacta gaggcagttt caaaggcaga
    47881 aacgaggtca tctggttttt caaccttacg aatcccttta ccacctccac ctgctgaagc
    47941 cttgagcata acaggatagc caattttttc agcaacaatc aaagcttctt cagagttatg
    48001 cacttctcca tctgaacctg gtataacagg cacacctgct ttaatcatct gagcacgcgc
    48061 attgatctta tcccccatca tatccataac atgaccagat ggaccgataa acttgatacc
    48121 tacttcttca cacatggtcg caaatttgga attttcactg agaaatccaa aaccagggtg
    48181 aatagcttct gcctcagtca agactgcagc tgatagaact gcattaatat tgagataaga
    48241 ctctgttgcc ttgccaggac caatacaaac tgcttcatct gccaaaagcg tatgaagagc
    48301 ttccttatca gcagttgaat aaaccgctac cgtcgcaatc cccaattcac gtgccgcacg
    48361 gataatacga accgcaattt caccacgatt ggcaattaaa atttttcgaa acatggagaa
    48421 cctccttagt tcccaattgc aaaagtaagg ataccactgg ctgcaagctt gccatccact
    48481 tcagcctttg cttcaaccac agctatggtg ccacgacgtt ttacaaaagt cgctgtcata
    48541 accaattggt cgcctggtac aacttgcttc ttgaacttaa ccttgtccat accagcgtaa
    48601 aagaccagtt ttcctttatt ttcaggtttt gataactcca acacaccagc agtttgcgcc
    48661 aaggcttcca taatcagaac acctggcata actgggtatt gaggaaagtg gccgttaaag
    48721 aaaggttcgt taatggtcac atttttgata gcaacaatgg tatcctcgct cacttccaag
    48781 acacggtcca ctagaagcat aggataacgg tggggaagag cttctttgat tccttgaata
    48841 tcgatcattt gatacgtacc aatcctttac caaactcaac catttcttcg ttagagacga
    48901 gaatttccgt taccacacca tccttaggag ctgggatttc attcatgact ttcatggctt
    48961 cgataattac caatgtttga ccttttttga cactatcacc aactgtaacg aaggcaggtt
    49021 tatctggtcc agcagccaag taaaccactc caacaagtgg actctctaca agatttccct
    49081 cactagccac acttgcttca gctggagctg gaacttcttc tgctacagtc tctgctggag
    49141 cagatgtagg agctactgga ttcggtgttg ctagaacggg tgctggagcg acttgagttg
    49201 caacttcagg cacaggtctc gcttcattct tgctaaactg caactcatcc gtcccatttt
    49261 tataagaaaa ttctctcaaa cttgactggt caaattgagt catcaagtct ttaatatcgt
    49321 ttaaattcat acttatctat tctcccaacg tttgaaagca agaactgcat tgtggcctcc
    49381 aaaaccaaaa gtatttgaaa tagcgtatgg aatttctttc tccaagcctt gtccataaac
    49441 gacattagct tcgatataat ctgatacttc acttgtccca gctgtcattg gtacaaagtt
    49501 atgacgcata gcttcgatgg tgacgatagc ttctactgca cccgcagccc ccagcaaatg
    49561 tcctgtaaaa gacttggttg atgatacagg tacttcctta ccaagaacag ctacgatagc
    49621 accactttct cctttttcat tggcaggagt tgacgttccg tgagcattga cataggctac
    49681 ttgctctgga gaaatctcag cttcttccaa ggctagtttg atggccttga tagctccctg
    49741 accttctgga tgtggagaag tcatgtggta ggcatcacaa gtatttccgt aaccaaccac
    49801 ttcagccagg atagtagctc cacgtttttc agcgtgttca agactttcta gaaccaacat
    49861 ccctgaacct tcacccataa caaacccatt gcgatcctta tcaaatggga tcgaagcacg
    49921 agttggatcc tctgtagtag agagagctgt taaggcttgg aaaccagcga tggcaaaagg
    49981 tgtgatagaa gcttctgttc ctcccaccaa catcacatct tggaaaccaa acttaatgga
    50041 gcggaaggca tccccaatcg catcatttga tgaagagcag gcagtattga tagatttaca
    50101 aacaccgttt gcaccaaaac gcatggctac attcccagaa gccatatttg gtaaagcttt
    50161 tggaagagtc attggtttga cacgtttggg tcctttttca tgaaggcgaa gtacctgatc
    50221 ttcaatttcc ttgattccac caataccaga tgcaacgata acaccaaaac gatccctatt
    50281 aagagcctct acatcaagat tggcatgatt tacagcctct tgggctgcat acaaggcata
    50341 taaagaatag ttatcaaaac ggttggtatc tttttttaca aagtatttat cgaacggaaa
    50401 atcttggatt tctgccgcat tatgcacatc aaagtcacta tgatcaaatt ttgtaatgcc
    50461 accaatgccg attttcccag ttgctaaact attccaaaat tcttctggtg tatttccgat
    50521 tggagatgtt actccataac ctgttaccac tactcgattt agtttcattc ttttcacctc
    50581 tagctttcgc tacatactta agccaccatc aatggcaacc acttgaccag ttagataatc
    50641 ttggcctgct aaaaatactg tcaaatctgc aacctgctct gcctgcccaa attctttcat
    50701 cggaatctga gctagtgtag cttccttaat cttatctgat aagatagctg tcatatcaga
    50761 ctcaatcatt cctggagcaa tcacattgac tcgtatattc cgactagcga cctcgcgtgc
    50821 cacagacttg gtaaagccaa tcaagccagc cttagaagca gcatagttag cttgaccaat
    50881 attccccatc aaaccaacaa cactagacat attaatgata gcaccttctc tggctttcat
    50941 catcggtttc aagactgatt gtgtcatatt aaaggcacca gtcagattga ccttgagcac
    51001 tttttcaaaa tctgcttctg tcatcttgag cataagagta tcttgggtaa tccctgcatt
    51061 gttgaccaaa acatctactg aacccagttc tgcaatagct tgatcaatca tacgcttagc
    51121 gtctgcaaaa tctgatacat ctcctgaaat gggaaccacc ttgataccat agtttgaaaa
    51181 ctcagcgagc aattcttctg agattgcccc acgactgttt aagacaatgt tggctcctgc
    51241 ttgagcaaac ttgtgggcga tggcaagacc aattccacga ctcgaacctg taataaagat
    51301 atttttatgt tctagtttca tttttttcct ttcaaaactt ctacttattt tagtctattt
    51361 ttctaaaagt gctactaaac tcgcttgatc ttccacatga gctaagtgag cagtttgatc
    51421 aattttttta acaaaacctg acaagacttt ccccggtcca atctcgataa agttgcttat
    51481 gcctgcttct tgcatgaccc caatactttc atagaaacga acgggttcct tgacctgacg
    51541 cgtcaagagc tgagcaatgt cctctttttg catcacagca gcttctgtat tgccgactag
    51601 gggacaagta aaatctgaaa aacttacctg agctagagtt tcagctagtt tctggctagc
    51661 aggctcaagg agagcggtgt gaaagggacc tgacacctta agaggaatca agcgtttggc
    51721 acctgcttct tgcaaaagtt caaccgctcg atcaactgca accacttctc cagcaatgac
    51781 gatttgtgca ggtgtgttat agttggctgg agtaaccact ccaagttcag aagctttttg
    51841 acaggcttct tcaatgacct ctactggcgt attgagaact gctaccatct tgccagagtc
    51901 agcaggagcc gcttcttcca tataggctcc acgcttagct accaaggcaa ccgcatcttc
    51961 aaaatccaag gcgccgcttg ccaccaaggc agagtattct ccaagagaca aaccagcaac
    52021 catatcaggc tgatagccct tttcttgcaa taaacggtag atagcaaccg aagtcgctag
    52081 aatggctggt tgcgtatagc gggtctgatt gagtttgtct tcttccgtat cgatgagata
    52141 acgtaaatca taaccgagca cctgactcgc tcgatcaatc gtttctttga caatcggata
    52201 ctgatcatag aaatcccgtc ccatccctag atactgggca ccttgaccag caaataaaaa
    52261 ggctgtttta gtcatttctt acaactcctg cccagcgaga ggcttcttct tgaattttct
    52321 tagcggctcc gtaatacaaa tcttttagga tttcttcagc tgtttcttct ttagaaacaa
    52381 gccctgcgat ttgacctgcc atgacagagc caccatccac atcaccgtga acaactgctt
    52441 tggctagggc acctgctccc atttgttcaa agatttctaa atcaggatct tcctgcttaa
    52501 aggcatcttt ttcagccagt tcaaaatctc tagtcaactg atttttaata gcacgaacag
    52561 catgaccaaa gtgctgagct gaaatcgtag tatcaatatc ccttgctttt aaaattttct
    52621 ccttgtagtt tggatgggca ttcgactctt ttgcaactac aaaccgtgtc cccacctgta
    52681 cagcctctgc acctagcata aagccagccg cagcaccttc accatccgca attcctcctg
    52741 cagcaataac aggaatagat atagctgtgg ctacctgtcg caccaaggtc atggttgtta
    52801 atttaccgat atgcccccca gcttccattc cttctgcaat aacagcgtct gcaccgattt
    52861 tttccatgcg tttagctaaa gcgacactag gaacaacagg aataacgatt atcccagctt
    52921 catggaaacg ttccatatac ttgcttggat ttcctgctcc tgttgtgaca actttaacac
    52981 cttcttcaat aacgagatcc acgatatctt ccacaaaggg agataagagc atgatgttga
    53041 ccccaaaggg tttatcagtc aatgatttga ttttatcaat attggccttg acaacttctt
    53101 tcggggcatt tcccccaccg ataattccta atcctccagc cttggaaaca gcccctgcca
    53161 aatcaccatc agcaacccag gccatccctc cttggaaaat aggatagtca atcttcaata
    53221 attctgtaat acgcgttttc atagtgcctc caaccttcct tgcttacgta atagttcgat
    53281 ttcaccataa tttgacagtc aaactattac ctaaacaaga gggagtgggt ttctccctac
    53341 tccttctact aatattctgc ttattttgct tgctcttcaa cgtaagcaac caagtcacca
    53401 actgttttca agtcattttc tgcttcgatt tggatatcaa aagcatcttc gatttctgag
    53461 attacttgga acaagtccaa tgaatctgcg tccaaatcat caaaagttga ttcaagtgtt
    53521 acttctgatg cgtcttttcc aagttcttca acgataattt cttgtacttt ttcaaatact
    53581 gccatgatag gactccttta aaataaatag tttttttata acaatgtgtt caccacatga
    53641 ttacctaaat tgtaagaatg agcgtgcccc aggtcaagcc tccaccgaag cctgatagaa
    53701 gaacagtctg gctaccatct aaagggatga gaccttgttc tacacactct gaaagtaaaa
    53761 tcgggatact ggctgcactg gtattgccat attccatcat attggctgga agtttggctc
    53821 ggtcaacacc aatttttcta gccatcttat ccaaaatacg gtcattggct tgatgaagta
    53881 gcagataatc caagtctgtc acctctatag gagattcatc aatagtctgc ttgatagact
    53941 tggctacatc tcgaatggca aaatcaaaga ctgtgcgtcc atccatcttc aaaaacgaat
    54001 ctgcactttc ttgatctgaa aatggagaat gcaaacctga atgcccataa gttaaacact
    54061 cgctgcgact tccatcgcta ttgagactct cagctaagaa atgctcttgc tcgctagctt
    54121 ctaacaagac accaccagca ccatctccaa acaacacagc tgttgatcga tccgaccaat
    54181 cgactgcctt agagagggtt tcactaccaa tcaccaagcc tttttgaaag cgaccagaag
    54241 cgataaactt ttcagcagtt gaaagagcaa atacaaatcc actgcaagcc gcggttaagt
    54301 caaaagcaaa ggctttatta gcgccaatat tagcttgaac acgagcagct gtagagggca
    54361 tcatcgaatc tggagtaatg gtagctagga tgataaaatc cagttctttt cctgttattc
    54421 cagcttttgc catcagtttc ttagcaacct ctgtagccaa atcactggta gattctgttc
    54481 ttgaaatatg cctttgtcgt attcccgttc gacttgaaat ccactcatca ttggtatcca
    54541 taatctgagc caagtcgtga tttgtaacca cttgctctgg cacataatga gcaacctgac
    54601 ttatttttgc aaaagccatt atttcaaatc ctccaaaaat tggtaaagat tagtcaagcc
    54661 tttacccatg acagcaattt cttcctcgct catgccatca ataatttttt ctaccatggc
    54721 cttgtggaag cgtttatgca gtctatgaat caagcgaccc ttctttgtca aatgcagatg
    54781 caccacacga cgatcctgtt ctgaccgaac tcgctcaatg tagcccttac gctctaaatt
    54841 gttcaaactt gtcgtaacag ttccaagagt taccatcaac tcttttgaca cttgacttgg
    54901 agtcacatct ggagccttac cgatgacatc aatcgtatgc atttctttga tggagatatc
    54961 cttaaaacga ctacctctca agttcacttc ctcaattaca aggacattgt taaatataga
    55021 tgttaaatat tcattgattc gttggtagtc catttttcat atccctcctt cttcaaaaaa
    55081 cttttacaat caaaacattt gacagaaaga attatatcaa aattcaaaga atgatgcaag
    55141 tattttttat tttcctgtaa atttaggtct tcttctctcc gaatgagctc gcactccttc
    55201 tttgaaatcc tctgtttgag ctaaggattt ctgtaggttc agttctaaag tagcgtaacc
    55261 ctgccagtct ttaaactggc tctcccaaac caacttctta atggcagcat aggaattact
    55321 tgaagcacgt cttaattttt taagaagctg ttctctcgtc ttttcaagtt tttcagcttc
    55381 agaaacgcgg taaaccaacc cccattctag ggctttttct gccgttaaag cctctcctgt
    55441 catagctaat tgagcagcac gcgtcacacc gatactgcgg ctcaagagat gaattccccc
    55501 tgcatctgga gccaaaccaa caccaacaaa ggcttggata aacttagcct tatccgtcgc
    55561 caaacagaaa tctgccgcaa cagccatatt cgctgcggca cctgcaacag caccgtcaac
    55621 ttccattaaa acaggtttgg ctatttgctt gattttataa gaaatcgtat tgaccaactc
    55681 tgcgattttt gtcaatgatg gaatatcatc ctcatccact gcccgcttca tctctaccaa
    55741 atctccccca actgagaaga cctttccatt ggcattgatt aagataaaat gcacagctgg
    55801 attttcttct gccaaagtca gagcttctaa aatctcctca cacatgggaa tatgaaaacc
    55861 atttgcgacc tcaggacggt tcaaggtaag gattgccaag tcctcttcaa gctgataaat
    55921 aatgtgttcc atcagggctc ctttttattt tataagcagt ttatactctt cgaaaatctc
    55981 ttcaaaccgc gtcagcttcc atctgtaacc tcaaaacagt attttgagca gtctgcggct
    56041 agcttcctag tttgctcttt gattttcatt gagtgttaaa ttatttcact gtcaaagtat
    56101 atctttttta ggagcagaaa gcaagaaaaa atcgactgaa agtgtctcag ccgataagaa
    56161 aggctcgctt taggctagaa agcatcttat tttcttcatt gaaaaaagcc tttctttctg
    56221 ctataatcgt ataaaatact tactttagga gttcttatga aagttgttaa atttggaggt
    56281 agttctcttg cctctgctag tcaattagaa aaagttttaa acatcgtcaa aagcgattca
    56341 gagcgtcgtt ttgtagtcgt ttctgcgcct ggtaaacgca atgctgaaga tactaaggtt
    56401 acggatgccc tgattaaata ctaccgcgac tatgttgcgg gtaacgatat tagcaagagc
    56461 caaagctgga ttatcgaccg ctatgctgct atggttagtg aattgggact aaaaccagct
    56521 gtgctagaaa aaatttctaa aagcattcac gccttggcca ctcttcctat tgaagaaaat
    56581 gaatttctct acgatacttt cctagcagcc ggtgaaaata acaatgccaa attgattgct
    56641 gcctacttta accaaaatgg tatcgatgca cgctatatgc accctagaga agctgggatt
    56701 gtggtcacaa gtgaacctgg tcacgctcgc atcattccat caagttatga caagattgaa
    56761 gaattgacaa acaccaatga agtccttgtc attcctggtt tctttggtgt cactaaggaa
    56821 aatcaaatct gtactttctc acgtggaggt tctgatatta caggttctat cattgctgct
    56881 ggtgtcaaag ctgacctcta tgaaaacttt acggacgttg atggtatctt tgcagcccac
    56941 cctggtatta tccaccaacc acactcgatt cctgagttga cctaccgtga aatgcgcgag
    57001 ttggcctatg caggcttctc agtccttcat gacgaggctc ttcttcctgc ctaccgtgga
    57061 aaaattcctc tggttatcaa gaataccaac aaccctgacc atccaggtac tcgtatcgtt
    57121 ctaaaacaca gtaatgatga atttccagtt gtgggaattg ctggtgactc aggctttgtc
    57181 agcattaaca tgtcgaaata cctcatgaac cgtgaggttg gatttggccg caaggttctg
    57241 caaatcctgg aagaacttaa catcggttgg gaacatatgc caacaggtat cgacgatctt
    57301 tctatcattc tccgttctcg ccaactaact cccatcaagg aagaagaaat cctgcgtcag
    57361 ttggttcaaa aggctaaagt agatcatgca gaaatcgaac acgacctttc tatcattatg
    57421 attgttggtg aaaaaatgaa gagccacatc ggagtgactg ctactgcgac acgcgctcta
    57481 tctgaaaaca aaatcaacat ccagatgatg tctcaaggtt ctagtgaagt ttctattatg
    57541 tttgttgtca ataaagacca agagaaagca gcaattaaag ccctctacaa tgcctttttt
    57601 ggagaaagta aggaagacta agcatggccc aatcacttaa caaaacagta ctcctcagta
    57661 cgacaggcac ttcctacctc tctatcgctg ggaaagttgg gaaattcctt gtcggagatc
    57721 aggctttgga attttaccca gatgtcaatg tcgaacaatt tatccagatt ccttggagcc
    57781 atatcaatca gattggagcc aatgtcactg gatgcaaaat cagccgccac ttcgaagtct
    57841 ttacagacaa aggaaaattc ctctttgctt caaaagactc aggtgccatt ctcaaaattg
    57901 cacgcgacaa attgggcaat gacaaggtcg tcaaacttcc gaccctgatt cagacaatta
    57961 gccaaaaatt taaaaatcta tttgcaaaaa aatagaaact ttagtataat catagcaacg
    58021 gataagtagg ttatcttctt ctttcagaaa gtctgcgggt gctgcgagca gataggaggg
    58081 ataggtgaaa ttctaccgtt agtaacaatt acatacacaa tcaagtgcac acctgtgaag
    58141 ttggatggaa ccgtggccct gccactccaa cgttttgtca ggtgtgcttt tttcataaag
    58201 gagttcttat gttagatatc aaacgtattc gtacagattt tgaagctgtc gcagaaaaat
    58261 tagctacacg tggtgtagat gctgctgtct tgaatgaaat gaaagaaatc gatgctaaac
    58321 gtcgtaacat cttggtcaag gttgaaactc tcaaagcaga acgtaacaca gtttctgctg
    58381 agattgccca agctaagcgc aacaaggaaa atacagatga caagattgct gccatgcaaa
    58441 atctatctgc tgaggttaaa gccttggatg ctgaattggc agaaatcgat gctaaattga
    58501 cagaatttac aacgactctt ccaaatatcc cagctgacag cgttcctgtt ggggctgacg
    58561 aagacgacaa tgtggaagtt cgccgttggg gtactccacg cgagtttgac ttcgaaccta
    58621 aagctcactg ggatctcggt gaagaccttg gtatccttga ctgggaacgc ggtggtaagg
    58681 taacaggcgc tcgcttcctc ttctataaag gcctcggtgc tcgtttggaa cgtgctatct
    58741 acaactttat gttggatgaa catggaaaag aaggctatac tgaagtcatc acaccttaca
    58801 tagtcaacca tgattctatg tttggtactg gtcagtatcc aaaatttaag gaagatactt
    58861 ttgaactcag cgataccaac tttgtcttga ttccaactgc tgaagttcct ctggcaaact
    58921 actaccgtga tgaaatctta gacggcaaag atcttccaat ctacttcact gctatgagtc
    58981 cgtcattccg ttctgaggct ggttctgccg gtcgtgatac gcgtggcttg atccgtttgc
    59041 accaattcca caaggttgaa atggtcaaat ttgccaaacc agaagaatct tacgaagaat
    59101 tggaaaaaat gacagccaac gctgaaaaca ttcttcaaaa actcaacctt ccataccgtg
    59161 tcgttgctct ctctactgga gatatgggct tctcagctgc gaagacttac gacttggaag
    59221 tgtggattcc agcacaaaac aattaccgtg aaatctcaag ctgttcaaac acagaagatt
    59281 tccaagcccg tcgtgcccaa atccgttacc gtgatgaagc agatggcaag gtgaaactcc
    59341 ttcatacctt gaacggttct ggacttgcag ttggacgtac agtggctgca attcttgaaa
    59401 attaccaaaa tgaagatggt tctgtgacca tcccagaagc acttcgtcca tacatgggtg
    59461 gagctgaagt catcaaacca taaaaaataa ggtttagcta tttctagcta gacctttttt
    59521 cgtaaccaaa tcagataagc acctagtaca aagaataaaa tagttaggca tataatggtt
    59581 tcagccaata ccaggtaatc cagaaatgga agtttcaaaa ttccctgagc catcttgagc
    59641 gaggtcgctg tgataatggt tgggaaggtg agggctgaga aggctggttg aaaaccttgt
    59701 tttaaaatgt tgggcagacg agttaaaaca aagaaaaaga aggattgaga agccaaaatc
    59761 atgacaatca agacccaatt cggcaggctg gttcctccta ctcgaactag agaagccaag
    59821 agtagagaga aaggagcaca gtagattcct tcttgtccaa gcaaggctag tgggagtgga
    59881 tgtttcttta aatcgctata aataagggga tagagataga aggtcaagag aaaaccaaaa
    59941 ctcaaggtcg cataggcaat ttcgataata cctaccagag gataggtcaa ggcagccact
    60001 gctatcccca catagagaac cgtccaactt ggagtggcat gaaccctccg ccctgaacaa
    60061 gcaaacttga tggtaaaacc agcaatcaag gtcaaatcca agagaaatga aaaccaccaa
    60121 atcccttgtg ctaccaaagg aagataagag aatacgcgaa agacataggt cgataaaatc
    60181 atcccagcca taggaaaggt tgccattcct gacaaaagag ggggcttggt caattcttgc
    60241 ttggtttctt tccaattaaa gagatgcaga attagaaagt aaatccataa aaccaaacca
    60301 gtcagactaa aaagatggga tagaaccggc aacgtatcta aaataagatt tccagctcct
    60361 gccaaaccta gcaaacaacc tgaaaatact aaggggagtt ttttcatcct aacctccaat
    60421 aatcatgtta gtttcagtat aacataaaag cgcttaaatg atgatttaaa aaaacgaagt
    60481 ccgattattt cagacttcat tttactcaga tatgaattag gcataaggtt gcaattctgg
    60541 attaattggt gtattagcta agttgttggc atagttacag aggattgcta ggctgacacc
    60601 aaaaaccaca tccaaggcat tttgttgagt gtagccagct tctaaaaact cagacaaggc
    60661 ttcatctcct acacgaccct tggtattgat aactgccaag gtaaacttag ctagggtatc
    60721 caatttagga tctgtttcaa ttggagtacg attgcgaaga gcttgaatca agtcatcatt
    60781 catctggatt tgtttgatgg aaaaggctgt gtgacctgcg acacagaagg cacaaccatt
    60841 ggtcacggct gccgtgattt gcaccacttc acgctcaacg ggtgtcaggc tgttgcgacg
    60901 gtggatagat gagacaattt ggtaggcttc taaaacagtc ggggcattgg ccaagagacc
    60961 gattaggttg ggaatatagc cattgttgtc tttttctact gtttcaagaa tttctttcac
    61021 ttctgctggt gctgactcta ctgtatggat agtaaatgtt gtcataagat acctcttttc
    61081 ttattattga cactaatatt attggaaaat cttataaaat cctgattcct aagtttatct
    61141 aagataaagc tttattctct cataagattt tcgttgttat attagtttat cacacttcca
    61201 atcacttgca taatatatat tatatatcag gctgataaaa attatttata ggcaaaaaaa
    61261 tcacacgagc tgtgtgattc cattatttgt caaaatactt tttagtttca gcaataacga
    61321 cttgcgacaa gaccaagagg gcaatcaagt ttggcagagc catcaaggcg ttaacgatat
    61381 ctgcgataat ccagaccata tccaactcga taaatcctcc taacaagacc atgagcacaa
    61441 aaaccacacg gtagagccag ataaagcgaa ccccaaagag gaactcaaaa cagcgttctc
    61501 cgtaatagtt ccaacctaga atcgttgtaa aggcaaaaag tacaaggaag atggtcaaga
    61561 gggcaggccc aaagtgtgaa aagactgttg agaaagctga ctgagtcaag gcaaccccat
    61621 tcaagtcacc actccaaact ccagttacca agatggtcaa accagttaga gtacaaatga
    61681 tgagggtatc aataaaggtt cctgtcatgg aaatcaaacc ttgctctact ggttcatttg
    61741 tcttggcagc tgcagctgca ataggagcag aacccagacc agattcgttt gagaacacac
    61801 cacgcgccac accattttga atagccatcc gaacgctagc accagcaaat ccacctaccg
    61861 cagcaagggg actaaaagct gaggtaaaga ctaaagcgat tgtgccaggg atttttccga
    61921 tattaaagaa aataactata agagttccta agatataaat gatggtcata aaaggaacaa
    61981 cagtagttga aaccttagaa atagacttga gtccaccaaa gactgcaatc gctacaaaga
    62041 cagacaagac gagagctgtg atgactggcg aaatcgtcgt tgtattttgg atagattctg
    62101 taatcgagtt gacttgggtg aaggttccga ttcccaagag agcaaccaat actcctgcta
    62161 ctgcaaacaa aacagcaagt ggtcgccact tttctcccat ccctagaagg atatagtgca
    62221 tgggacctcc cgctactgca ccatggtcgt ccttggtgcg gtatttgatg gccaagagtc
    62281 cttccgcata cttggtagcc attccaaaga aagccgccat ccacatccaa aatagagctc
    62341 ctggtccacc aaccttgata gccgtcgcaa ctcctatgat atttcctgtt ccaacagttg
    62401 atgccaaggc tgtacacaga gctgcaaaac tggatacatc accatgtccc ttatcctgga
    62461 taaaaataag ctgaaaggcc ttgggcagac gcaaaacctg caagagtcct agccgcatgg
    62521 ttaggtaaat ccctgttccg accaataaaa tcaagagggg cggtccccaa gcaaaatcat
    62581 cgattgattt aagcaattct aacatttcct tctcctatcg tttcaacccc aaaagaaaga
    62641 gcacatgcaa gatacatgta ctctggaatg cttagataaa tgctaaaaag cggtctatcc
    62701 tagctctgtc cttttacctg agagtttgag cagttgcctg ccttgcccct tcggtgcctt
    62761 tacggtctct ccagagttcc gtccatttac agtcatggaa aatcaaacga ttccccactt
    62821 ctattaaact tcattcggtg ttggtattta attgattcta attttacaaa aaatgttggc
    62881 ttttgtcaat gtgtttatta gtaaaaatta gttcaacagt ttttacttta taaagtccag
    62941 aatactgcta tcctttaaaa gtgacaatag tcgcaccact gcctccagca ttttgtgggg
    63001 catagccgaa actcttgaca tgtttgtttc tttgcaagta tttggtaact ccttcacgga
    63061 tgactcctgt tccgatacca tggatgatat caacttgagc catattgtta agcaaggctt
    63121 ggtcgatgaa ggtatctagc tcattcatgg cttcttcata gcgcttgcct cgaagatcca
    63181 gtctagcttg aggtcctcgc ccagaagttc gtttcacaac attgacctgt ttcttcttga
    63241 ctggtttttc ttgctgggct tgaacaagat caaactcttt ctcttccaag gtcatcttaa
    63301 tcaagccaac ttgggcttcc cagcggccgt ccttgagttg actggtcaag gtaccacgct
    63361 gaccataact gagaaccacg atatcatctc ccacctttgg agctcgtttt ttcttggcct
    63421 tttgaaggac cttgttttta gacaagtcca ctttttcagg agccaatttt ttcaacttgg
    63481 ccttggcttc aatgatttcg tggggcttga gttgggattt actgtggaga tttttgagaa
    63541 tctggtcact ttcacttagg gccatatcca caatctcagc agcctgttca cgcgccttgt
    63601 taagctcggt ttccttttca cgattaagct cgttgtagag tttttttagc gcacggttca
    63661 tcttgagatt ttcttgctcc acctcacgga tattgtccaa acgtttgcgg ctttccagcg
    63721 tctgctcttc taattgctca atgatacgat tgacgtcatt gtcctgatcg atctgctgac
    63781 tggcatctcc tacgataact tcagataggc ctagacgttt ggcaatttca aaggcattac
    63841 ttcggccagg aacaccctgc ataaagcgat aggtcgggcg aagagttgca gtatcaaact
    63901 ccatactggc attttgcaca aaggctgtct caataccgta ggccttgagt tctggatagt
    63961 gggtcgtcgc catggtcttg atttgacgca ggcgaaggtc ctccagaata gccatggcaa
    64021 gggctgctcc ctcttgggga tcagtaccag cccccaactc atccaaaagt aagagtgaat
    64081 gttggttgac cttgccaaga atatccacga tattggtcat atggctagag aaggtagaca
    64141 agctctgctc aatagactgc tcatctccaa tatcagcaaa gatttcttca aaaataccaa
    64201 cacgacttcc cttgtctgct aaaatcggca atcctgactg ggccatgacc tgtgtcaagc
    64261 ccagagtttt gagcatgatg gtcttcccac ctgtattggg acctgtaatg acaatagctg
    64321 ttaaatcttg accaaaatag acatcatttg cgacggcatt tttgaccaaa ggatggcaga
    64381 catggagcag ttgaatctct tgattttctg acagctgagg cacgactgct tgtctttctt
    64441 ggataaatcg aaccttggca cgaatcaagt ccagatgacc gataatccaa gcgtcattag
    64501 caatctcagc cgcatgaggg cggacacgct cagaaatttc ttggagaatg cgaagcattt
    64561 catagcgctc atctgctcgc agactagcaa tttcttcgct cagtttgact acctcacgtg
    64621 gttcgatata gacggtgttt ccactagcag aaatatcatg aacgacacct gcaatcttat
    64681 tgcggtaggt gtttttgact ggtaaaacct gacggccatt tctgctagca acaattcctt
    64741 ccgtcaacat ctgcgctttt tgcttgagta agtcttgtaa aacatcgcgc acctgactct
    64801 cgctatcatg tatttttcga cggattcgcg ccaattcttc actggcaaaa ttttcaatga
    64861 aacccgcatc attaaaggcc tgaagatttc cttgtaattg cggaaaatca tgtaatttct
    64921 caaaccaaag ggctaattct tccaagctga cattttccag attggcgtaa aaattttgaa
    64981 gttctcggct ggcaagaagc acgcgtttca agagtaggaa ctcctcgata ttgagatccg
    65041 ctcccatctc caacctcttg cagactcctg caatttcctt agttgagaga atagtaaaat
    65101 gcggttgctc gacgaaaaga gcctgcattt ctttcatctc agcaaaagcc tgtttgattt
    65161 tatctgcttt ggcagtcgga gccagctgtc tcaattgctc caagccctgc tcggtcaaca
    65221 aatgaggctc aaacaaggcc ttgaccttat cgaactctaa tgtttctaat attttcttat
    65281 tcatctttat ttccttgtct ttgaatgtct aggtgtggta gctttttaca ttctgataga
    65341 ttcgagtcaa atctgtaaac aaagggctag gaaaactcct gcccttttta tccgattaaa
    65401 tttgtcaccc agatttgttt gagccaactg gttgttaccg gtatgctctg gatgatgtgt
    65461 tttgcgacga tactcttttc aagaggattt tgtataactg ccatggggat ggtcgccaag
    65521 attgtcaagg ccatttgcaa gacaaataag gtcaccaaca tggacaagat acctgctgaa
    65581 acttggaaca acttaccacc cagttttttg ctaggaatca agtgtaagag aagaccaagt
    65641 aaacgaccaa tgctatagac aatcccaaat acaagcaagt agccgatacc tgcataaaag
    65701 accttatcca gctgaaagag ttgatccgat gggaaaaaga aagtcccctg accttcctgc
    65761 gaatttgcat aagggagcaa taaatggaat tgctctccaa gccccttata aaactggcca
    65821 gccataaaag ccgatgccat ggctgaaatc aggtaataaa cctgtaagag caggcctctc
    65881 cgatagccga tataaaatcc ccaaaccaag accaatagaa gaaggaatga aatcataagg
    65941 aatcctcaat cttgctctgt tcttgcttac aagtcacaag cttgtgacgg agttcttcta
    66001 gctcttgctc cttatcgtca aattcaatct cacggctgag ctgagttgat aaacagttga
    66061 ctgccaacaa aagagcgatt gtttcatcat ctgcgctagg catttgttct ttaattgctt
    66121 ggtatttttc tgtcgcaacc ttagcgattt cctccataaa aaggttgtca tgttcgcttg
    66181 tcaaggttaa cgattttttc ccgaatgtaa atttgaatcg atttagattt gccataaaat
    66241 tcacctcacg atattatacc aaaattcgct aattttgtca gtttttacaa attttactgc
    66301 ttttgtggta caatagaaac tatggcaagt atcacactca caccaagcga aaaggatatt
    66361 caggcttttc ttgaacacta tcaaaccagt ctggctccta gcaagaatcc ctatatccgc
    66421 tactttttga aactacctca agcaacggtt tctatctata cttctggaaa aatcttgctt
    66481 cagggtgaag gggctgaaaa atacgccagt ttctttggct atcaagctgt agagcaaacc
    66541 agcggacaaa atcttccttt aattgggaca gatgaggtgg gaaatggttc ctactttggt
    66601 gggcttgcag ttgtggctgc ctttgtcaca cctgaccagc acgacttttt acgaaaactc
    66661 ggtgtggggg attctaagac tctgaccgac caaaagatcc gtcagattgc tcctattctc
    66721 aaggaaaaaa ttcagcacca ggcactcctt ctctcaccca gcaagtacaa cgaggtcatc
    66781 ggagaccgct acaacgctgt ttcggttaag gttgccctcc ataatcaggc tatctatctc
    66841 ctccttcaaa aaggtgttca gcctgagaaa attgtgattg atgcctttac cagtgctaaa
    66901 aattatgaca agtacttggc acaagaggcc aatcgtttca gcaattctat cagcttagaa
    66961 gaaaaggctg agggcaaata cttggctgtc gcagtttctt ctgtcattgc gcgtgatctc
    67021 tttctggaaa atcttgaaaa tttgggacga gaactgggtt atcagcttcc aagtggagct
    67081 ggaacggctt ctgacaaggt ggctagccag attttgcaag cctatggtat gcagggactc
    67141 aacttctgcg ctaagctaca ctttaaaaat actgaaaaag cgaaaaacgc ttagaaaggt
    67201 aagttatgaa tttatttaaa aatttcttaa aagagtgggg attattcctc ctgattctgt
    67261 cattactagc tttgagccgt atcttttttt ggagcaatgt tcgcgtagaa ggacattcca
    67321 tggatccgac cctagcggat ggtgaaattc tcttcgttgt aaaacacctt cctattgacc
    67381 gttttgatat cgtggtggcc catgaggaag atgggaataa ggacatcgtc aagcgcgtga
    67441 ttggaatgcc tggcgacacc attcgttacg aaaatgataa actctacatc aatgacaaag
    67501 aaacggacga gccttatcta gcagactata tcaaacgctt caaggatgac aaactccaaa
    67561 gcacttactc aggcaagggc tttgaaggaa ataaaggaac tttctttaga agtatcgctc
    67621 aaaaagctca agccttcaca gttgatgtca actacaacac caactttagc tttactgttc
    67681 cagaaggaga ataccttctc ctcggagatg accgcttggt ttcgagcgac agccgccacg
    67741 taggtacctt caaagcaaaa gatatcacag gggaagctaa attccgctta tggccaatca
    67801 cccgtatcgg aacattttaa gaaacctaag aggccgagaa tcaccaatct cagcctcttc
    67861 ttctatcgtg agaaaatgat tggtaactat ctaaacttac cagaacagaa acacctcaac
    67921 tctcacctat tcatgcaaag gaattttatg gaagtttatt tttcaggaac cattgaacgg
    67981 attatttttg aaaatcccag caatttttat cgcatcctcc tcctagaaat cgacgatacg
    68041 gacgcagagg attttgatga ttttgaaatc attgtcacag gaaccatggc tgatgtaatt
    68101 gagggcgaag actatacttt ttgggggcaa attgtccagc actccaagta tggagaacaa
    68161 ctgcaaatca gtcgttatga tcgcgcaaaa ccaactagta agggcttggt caagtacttt
    68221 tcaagtagcc atttcaaggg gattggtctc aagacagctc agaaaatcgt ggatacctat
    68281 ggcgaaaata ccattgacga aattttgcaa cacccagaaa agttagaagg catcgcagga
    68341 ttctctgcca aaaatcgcga ggctttcgtc tccactctcc gtctcaacta cggaacggag
    68401 atggttttgt ccaaactagc caactacggc attcccaaca aactagcctt tcagattcaa
    68461 gacttttaca aggaagaaac ccttgatgtg gttgaaaatt atccctacca gctggttgag
    68521 gatatcaagg gtttgggctt tacaattgct gaccaactag ctgaggaact aggcatcgaa
    68581 agtcaggctc ctgaacgctt ccgcgccggt ctagttcaca gtctttttca ggcctgtatg
    68641 gaaacagggg acacctatgt tgaagcacgg gatttgctgg aacaaaccct tactctcctt
    68701 gagtcttccc gtcccgtgga actagacccc agccaagttg cccaagagct ctcctacctg
    68761 atcgaagaag acaaggttca gcagattgat accaagatct ttgacaacag cctctttttc
    68821 gctgaggaag gtatccgcag tcacttgatt cgtatccttg aaaaaggaaa acagaagagc
    68881 caagatttag aaactattca aaagcatatc actactgtcg agcaagagct gggaattgag
    68941 tatgataaca ttcaaaaaca ggctatctgt gatgctatcc agaataaggt ctttatcctg
    69001 acaggtggac ctggtactgg taagacaact gttatcaatg ggatcatcgc tgtttacgcc
    69061 ctgttagagg gacttgacct caggaagaaa agcaatctgc ccattcttct tgctgctcca
    69121 actggacgag ccgctcgccg catgaatgaa ttgacaggtt tgcctagcgc gaccatacac
    69181 cgccacttgg gaatgacagg tgacgatgat accagtcatc tggaagatta cctagatgct
    69241 gactttatca tcgtggatga attctctatg gtagatactt ggctggccaa tcaactcttc
    69301 tccaatatct cttctaacag taagatcctc atcgtaggtg acagtgatca gctaccttct
    69361 gtcagtcctg gacaggttct agcggatctg cttcatattc ctttgattcc tcagactcgc
    69421 ttggaaaaaa tttatcgaca aagcaaagaa tcaaccatcg tcaccctagc tagtcagatt
    69481 cgacagggca tcttgccagc tgatttcacc caaaaaaaag ctgaccgttc ctactttgaa
    69541 attgctagtg gccatattcc tgccaccatt gaaaaaatct taggtgtcgc cctcagaaat
    69601 ggtattcctg cccgtgatat ccaagttctg gctcctatgt accgagggac ggcagggatt
    69661 gatgctatca atcagctcat gcaagacctg ctcaatcccc cacaaaaaga tcaactcagt
    69721 tttgaagctc ctcagtgcca ctatcgtaag agagacaagg tcattcattt ggttaacgat
    69781 gctgaaatca atgtctttaa tggggattta ggagctatca cagacctgat tcctggtaaa
    69841 tacaccgaat cgaaacaaga cgagattgtc attgattttg atggtaatga agtctcttac
    69901 ccccgtaacg aatggtacaa gattcgcttg gcctatgcca tgagtattca taagtctcag
    69961 ggaagtgagt tcccagttgt catcctaccg attactagtg ctagccgacg tatgctggag
    70021 cgaaatctca tctacacagc cattacacgt gccaaaagca aactcatctt actaggcgaa
    70081 ttacaagcct tcgactatgc tacccaacac atcggaactg cccgaaaaac ctatctgatt
    70141 gaacgcttca gtgatctact ggagaatgtt gaagaaaagc aacaagctgt ctctgaaaca
    70201 gtcacatcaa gtgcctctga acaatcctac atcctaaccg aagaaaactg ggaccgcatc
    70261 ccagccatga ttgggattac agacacagac ctcaaagaga tttttggaaa atagtgcatc
    70321 agaaaaccca ccaattcagg tgggttttct gtttattaag attattttac tgttgctgtg
    70381 cttgtgatca attcaacagc ttttttgata gtgatatcat gtttcaacat gtcagctgaa
    70441 agcaagtttt gaacttgtgc aacttccatg ttgtagtctg ctgccaattg ctcaacttct
    70501 ttttggattt cttcttctga agcatcaaat ccttcagctt tggcaactgc ttcgataaca
    70561 aggttagtct tagtacgtga ctcagcttct gcttggtatt ggttgtgaag gtcttcttga
    70621 gtagttccag tgatttggaa gtacatgtca gggttgatcc cttgacgttg caaattccca
    70681 aggaattcat ttactgaacg gtgaacttct tcatggatca tttcttctgg aagttctacg
    70741 atttcagcat tttctacagc tgtatcaatt gctgcacctt caactgcatc tttgtaagct
    70801 tcttctttag cagcagccaa ttctttgcgg tatttttctt tcaagtcagc aagtgtttca
    70861 acttcttcat caatgtcttt tgcaagttca tcgtcaagag ctggaacttc tttagctttt
    70921 acttcgtgga tagttgtcac gaatttagct tctttacctg caaggtcttc tgcttggtag
    70981 tcttctggga atgttacgat aacatcaacg gtttcgccag ctgagtgacc taccaattgg
    71041 tcttcgaaac cagggatgaa ttgacctgaa ccaagtccaa gtgagaagtt ttcacctttt
    71101 ccgccgtcaa attcaacacc gtcgatagaa ccaacgaagt cgatcacaac agtgtcgccg
    71161 ttttcagcag cagcttcctt gataaccaat tcagccaggt tgttgcgttc gcgttcgata
    71221 cgctcttcaa catcagcgtc agttacttct ttttctacat caactgatac ttcaaggttt
    71281 ttgtagtcac ccaattttac ttcaggtttt gtaacgactt cagcagcgat aacccagtct
    71341 tgaccttttt ccattgaagt tacgtcaatt tttggttggg caaccacttc aagaccagct
    71401 tcttttacag ctgcttcata agcgtttggc aaaagagcgt tcataacgtc ttggtaaagt
    71461 gattcttcac caaatttttt atcgaagata ggacgtggaa ggtgaccttt acggaaacct
    71521 ggaacattaa gagatttctt cactgacttg aagacacggt ccaattctgg tttgatttgg
    71581 tcttgagaga tagtgaaagt caagacacca cggtttgttt ctttgttttc aaatgataca
    71641 gacattctgt catttctcct taaaattttt taaatacagt ctattataac attttctata
    71701 aataaaatct agactaatgc agccaattat agacaacaag cctttttcct aactaaaaca
    71761 ctcataaagt atagacaatt ttagactact ttggatatct tttggttagt cattttccaa
    71821 aactaattta tctaattttt cagttatatt tgacttcatc ttctcagtaa catgagtata
    71881 aacacttaaa atctttgttt cattagtata atctacacga tccattatcg ctgttatagg
    71941 tacttccaat tcagcaagca aacttatatg cgaatatcta aaaacatgag cagtcaatac
    72001 aaaatcatct ttcttaattt cacttttcct aaaactgttt ttcaaaaagt aattgaaaca
    72061 agttatcatt aagggagaac cattatttgt aaatatataa tcaccttctt ctaaaagaag
    72121 atattctttt aaaatttcta acactctatc actaatacca attactctat atgaagctaa
    72181 acttttcgga ctatccaaaa atacttcgtt attggacgat tacattatag taaaacgaaa
    72241 taagaacagg acaaatcgat caggacagtc aaatcaattt ctaacaatgt tttagaagta
    72301 gaggtgtact attatagttt caatctacta tacaagacga aattgaagaa atctttccat
    72361 tataaaacgc atattatcaa ggtttttaaa cacctaataa tatgcgtttt ttcctatttt
    72421 aaagactttt atccacctat tatacaaagt taagtatcca tcacagttta caattagcct
    72481 tcattaccta acccattcac catccttcaa gagagtaacc tttaagaacc gaataaataa
    72541 atggcaaatt tcgttcattt aatttaactg cactgttaat ttgattagct ccatctccta
    72601 aagtatgcac tcctactaca cggtgactag catcataaac tgtagatcca ctagacccct
    72661 ctaaagtatc aacttggtaa tccaagaaca tgccatcatc acttaaaact tgttttttat
    72721 ctgtatacat ttgatgaatt ttaaaattat atgatagata gcctgtgata gtcacagtta
    72781 ttcctgtcaa atttttttga ctagtaggaa gacccaaagt ccctaatttt gcaccaatgg
    72841 gctcttctag aattaataaa gccaagtcat attcccttgc atccttagaa tttaaatttc
    72901 taaattcctt caaataacga acttccttta ctttgatctt tccaaatagt tcttgacttg
    72961 gactaacagc cggaagaaca taaatatcat ccgcttcttt cccatagtca tgtctgtagt
    73021 agttgtgagc cgctgtaatt aacacattat ctttaataaa attcgcactt cccctccctt
    73081 ctacattcat tccatcggct actccataat acttagataa aaccatagct gaagtcgaat
    73141 acggatactg taaagtatta tcaattttaa tcaaatcatc attaccgata atacttctga
    73201 ttgcttttgg tagtatgaac catacgttgg tgaaatctca gataatgaag aatcattaga
    73261 ctctggacct ttttctagtg tctcacttac ctcatattct tcacctgtac tagaaataac
    73321 actcaaagca gatactgtcg ataactggct agccaataaa gtactcgcaa taattgaaat
    73381 acccaatttt ttataaacag ttttcttcat tattgtatcc tcctaatgta attatagcgt
    73441 actattctaa atttcttaat ctactataga atcaagaaat ctaccacctt ctttaaatac
    73501 cctccattat cacataaaca ggtaaacttt tcaattaatg actgcgcttt tcaatcacgc
    73561 tagaggtact tgcttgcttc tttgatacta agttcagcca ttctttcctt gtttttctca
    73621 ataaagcatg ttacccaagt gggattcgtt ttggagtagt ctcgcagagt ccagccaatg
    73681 gctttattga taaaaaattc tgtttggttc aagttatgaa gtagaatctt ttccattaat
    73741 tgagtattgg tcttctcttt tcttaacaac tggtggtcaa tagcgacacg tctcagccag
    73801 atattatctg ataggctcca ttttatactc aatgaaaatc aaagagcaaa ctaggaagct
    73861 agccgcagat tgctcaaaac actgttttgg ggttgcagat agagctgacg tggtttgaag
    73921 agattttcga agagtattaa gattatttct tctagttcag agtgttcata caccaaactc
    73981 cctactactc gatctaggat atctaccgtg tcccaccagg attttgtcac gactaactgc
    74041 tctagcttag gcaaatcggt ttcctttaga taagactgca ttgctttcaa atagttagca
    74101 gccacatatt ggtattctct aggatccttt tcccagcaag tgtctgcaaa atcccaatcg
    74161 ataatctttg tttttttcgc ttctggaaaa tatttttata gagtttattt ctttcaggca
    74221 ccgcaatacc tagaaaagaa aattgatggc gcatataggc ttccatggac cttgcttttt
    74281 tagagtcttt tgctgcttct agctcctcaa gtaaatctgc taaactcatc taaaactcct
    74341 cttgccccac caaatggtgc tgaaaggcat agacagccgc ctgggtacga tcgctgactt
    74401 caagtttggc aagaatattg gacacgtggg tcttgaccgt cttgagagag ataaagaggt
    74461 catctgcgat gcgctgattt tcgtagccct tggcgatgag ttggagaaca tctcgctcac
    74521 gcgcagtcaa ttcttcatga agttccatat gattgcggtg gtattcaacc ttcttgctaa
    74581 cctcttgctc aatggccagc tcgccagcag ctaccttact gacggcatga agcaattcat
    74641 ctgcactaga agtcttgagc atatagcctt tggcaccagc atctaagact ggcatgattt
    74701 tttcattgtc caaataagag gtcacaatca aaatcttggc ttcaggccat tctttaagga
    74761 ttgctaaggt cgcgtcaatc ccattcatct caggcatgac aatatccatg acaatgacat
    74821 ctggacgcag ttccaaggcc aagtcaatcc cttgagaccc gttggacgcc tcacccacaa
    74881 cttctacatc gtcttggagg tcaaagtagc ttttcaagcc caatcggacc atttcatggt
    74941 catctactag taaaattttc atctttactc ctttatcatt ccttatctaa caggggaata
    75001 cggatatcaa ccgccagccc ttgcttggga gctgtcaaga gttgaactgt tccagccata
    75061 tcttcaaccc gctccttgat atttcgcagt ccataactca agtcgtctaa gctccctaac
    75121 tggaaaccaa tcccattgtc caccaccttc agttgcaatt caacatctgt ctgatagagg
    75181 tagacatcta ggcaagatgc ctgggcatgg cggagggtat tgctaatcaa ctcttgcagg
    75241 atacggaaga tatgctcctc gattttctta ggcaatttcg tcatattctg cttgagacta
    75301 accctaagat cactcttgtc ctcaagctct tttaagagaa tttgaatccc ttctatcaag
    75361 ctcttctgct ccagttcaac tggtcgcaaa tgcaagagca aaacccgcaa atccttctgg
    75421 gcagtttcta aaatagctgt gacactctgc aactggatct gcatcttttc tctatccaat
    75481 ttcaaagcct gctgactgat acccgataaa atcatgtggg ccgcaaacaa ctcctgactg
    75541 actgtatcgt gcaaatcccg agcaattcgc ttccgttcct tctcgatgat ttcctcttcc
    75601 tgagcaaggc tatgattttc agctttttga agagcttctg tcaaaaggtt aagtttacct
    75661 gataaggact tgaaactggc atccaaatct ggatctgcaa cctgaaccac ttcttgccct
    75721 gccaataaac gcttgagatt agcctgcatt tttcttagag aaagctcttc gatccctcgc
    75781 caaaacaggg ctaagagaca ggttatggac atgctgaaaa ccaacaataa aaagacaaat
    75841 ttttctgttt tttcgacatc gtgcaaaaag atagaccagt caaaatcaag tatttccagc
    75901 aagctgtggg agaaaaaaaa gacaaacagg aaggaggtga gagcaataat gacataggct
    75961 tgttttttca tcctctaacc acctccacat caccaatcat agtggtcaag aaaatcttga
    76021 cactcttgtt actcttgaga tagtcttttg tttcttgatg atagtgttca ttgcggaggg
    76081 ctcgcttggg ctggttgaaa aaagtcaaat ccccatagag acagttaacg ctgagactga
    76141 cttccacatc tacaggtacg atgattttgg tcgttcctac catctttctg aggataatga
    76201 cattgtcatg attggttaag atgaccctct ccagatgaat agtgtccttg cccatgaagc
    76261 gaaagagatt gatatcatcg aattggcaag tctggtagct tgaaaaatga tgaagatttc
    76321 caaaccaacg atttttctcc ttcttaaccg tcacgacctc ttcaaaaacc aaattggtct
    76381 gctctttttc ctggttcatc atcgggtaaa gaagaaagag gctatagata accgcaacaa
    76441 aaatagctag aatcacaaaa ggattgagca taacgatgaa aaagaagaga atggttgccg
    76501 ctactaaaag aagattattt ccctctttac cagtgtagta gcgaatcaaa agcaaaaaga
    76561 ggaatagtat cagcagaaaa cgcgaaaaat gctctgatac catcaaaatc agagctcctg
    76621 tcagaagaca ggcttcgata aataaaaaga ttttaaattt tctcataggt tcatcctctc
    76681 ccttctattt tatcacaatt caaaaaagtc acctcagtct gaggatggaa aaaaggcgct
    76741 ggttacgcct ttttcatctg atcctttgct tcttttaatt ttccataaag aagatagtct
    76801 actttttgta gatctgctat ggtggcacag ttaagggaac acataatcaa gcgtaggtct
    76861 gctttccagc cttggacaat gccaatcact tcttcaactg tgtaggtttc aaccaattcc
    76921 agaacggttc gtgacaatcc cacagactta gcaccaaaaa ccaagcactt aatcatatcc
    76981 agcggattcc gaacccctcc actaaccaag agttcgacct tatctttcca ttcttgggca
    77041 ttgagaaggg cctgcatggt agactgaccc cattgattga ggtaatcacg ctggccacta
    77101 cgacggtttt cgatataggc aaagctggtg ccaccacgac ccgataggtc cactgtacga
    77161 acaccgaatt cataggctct ttcgattgtc ttggcatcca ttccaaagcc cacttccttg
    77221 aggacaatag gaacgggaat ttgctcgcta taatctgcta gatgcgattg ccagcttcta
    77281 aacttccttt ctccctcggg catgagtaat tcctgcatga cattgacatg cacttgcaat
    77341 agaacaggat tcatctcttc tacagtctga agccctaact cgacaggctt gtccaatcca
    77401 atattggttc caaggaggag attgggatga ctagacttga cagaaaaaga atcatccgtt
    77461 ggatttttga gggctgcgct ataagaaccc gttacaaata aaataccaca ggattccgcc
    77521 acctgagcca gcttttgatt gatttctctt cccttattac ttccaccagt catggcattg
    77581 atataaaaag gaaagtccca ctttcgacca gcaaactctg tcgaaagatc gatttcatcc
    77641 agattgtaaa gaggcaagga agaatgaatc agctccacct catcaaagct attataggaa
    77701 cttttctgct caagggcata gaggatatgc tcgtccttac gatttgtcgt catgtcctat
    77761 cctttcttga tataagagct caatccccag atcggcccaa cgatttttta aggtttcggt
    77821 tgattgcgca tcaaaactca aggcgatgcc acagtcacca ccaccagcac cactactctt
    77881 ggcaacggcc tgcaaatctt gactggcttc tttcaactgt ctaagcaaag gcgtgtaaat
    77941 atctgtactc aagccttcta aaagcttgct ggctacttct acttgctcga taactttttc
    78001 ggctttcccc tgctccaagg cttcgaccaa agaaaccacc gtttcttttg aggaacttaa
    78061 aaaattttga ttgatatttt gcttgatttg ctggaccatg tgactcgata cagccacttc
    78121 cttggtccat cccactaaga aatcacattc taaagttggt ttcacttgtg agataaaaaa
    78181 tccccaatca cgctccagaa ctgtcgccaa gttttcttct tctaaccaag cagccacctt
    78241 ctggcgatca aatgactggt agagaaccaa atcctctgcc acaatacagg caaggtcgcc
    78301 catggaacca ttgtctcctc gcttgagcaa gacagcgcta gtcagcttga acaagagatt
    78361 ctgatcaacc gaaagattat agagagccag taaagccttg acaaccaaga caacgacgct
    78421 gccactagaa cctagaccaa actttttccc ttctcgttcc attttgccac agatttttag
    78481 ggaaaaaggt cttaaattct gaccgcgaac agcgaggaag tctcccatca aagcaatcgt
    78541 ttcttgaatc aagctgtagt caggattagg ccttaagtcc actgcgaaat caaacatatc
    78601 tgaatagata cggtagctgt cagaaaaagc aatttcagcc ctcatataga tgggaatatc
    78661 ctttatcaaa gctaactgcc ctggctctaa aatagcatat tcacctgccc aatagagttt
    78721 tccgcaagtt ttaacagcaa tcatcttgac tcaaatcctt tgtttttgac acaatcaagc
    78781 gataacgctg accgaaaatt tctgataaat gctccaagtc tttctcctga cagaagacct
    78841 taacattggg accagcatcc atggtaaagt agcaggcctc tcctttctca cgaagctggc
    78901 gaacaaagtc catagcctca taagaggcat ccgtcagata agaaaaggct ggactagcag
    78961 tctttgtcgt agcatgcata gccagggcat ttttctccgt taattctcca atcttggcaa
    79021 aatcattttc cttgagataa atcagcatat cctgatagtc cttctcagac tgacgaaccc
    79081 agtcgtcgaa agtcgtcgag gtttccacac aaagtttcat cccgtcacgg ctagagattg
    79141 gttttttctt gtcctctagc accaacataa tcatagctag tttcaagtct gtctctacag
    79201 ggtaaatttc tccactatcc ttatcccagg ctcctagtgg tccataaaaa ctccgagaag
    79261 aagagcctga ggcaaacttg gcttcctgcg ctaactgact tctatccaat ccaagcttga
    79321 aataagcatt acaagccttg accagggcgg acaaaccact agaacttgag gacaggcccg
    79381 ctgccgtagg catattgttt tgagtatcga tacggacaaa gccctcacca gctggacgat
    79441 aacggtcaat aatcttactc atcttggcat gctcgacctc attttgtagc tgaccattga
    79501 tgtaaaattc gtcagctgtt acattggctg gtaaaggcga caaggtcgtc tctgtataca
    79561 tattttccaa agttagagaa atactgctag tagcaggcac catctctttt tcttttttct
    79621 ttccccaata tttgataata gcaatatttg cgtaggaacg tactgttaca ggctctctat
    79681 ccatgtctga acagctcctt tctcttctaa tctttctgct agttcttgtg cgtgtgtcaa
    79741 attggttacc aaggctatga tacaacctcc tagcccacca ccgctcatct tggcacccag
    79801 agcaccatgg ctaagagtcg tttcaaccaa aaagtctgcc tcagggctac tgactccaat
    79861 ttcttttaaa tgtaaatgcg cttgactgag gatttgtccc agtccttcag catctttttg
    79921 tgaaatcgca acttctgctt gctgggttaa ttctcccaag gcatgcaaaa acggtagggc
    79981 atccttgccc ttattttgaa ccacttggat ggcttcacga gtatgaccat aaacacccgt
    80041 atcggcaatc accaaatagg cggataaatc catctcaagt tctgtaaatc ctacgttctt
    80101 gataaagcga ataggttggt cactgagaca ggtcttagca tccaaaccac taggattcat
    80161 atgggcaatc atttcagctc gattgaccaa gatttctagt acatcatgag gcagatcagc
    80221 ctgatagtag tcaaataccg cacgaatggc cgctatgctg atagccgctg acgaacccat
    80281 cccccgtttc tcagggatag ccgagtcaat ctcacaacga atgcaggctt ctgtgatatc
    80341 caaatactcc agtgaggcat aaaccgccat ggacaaggta tcctcctcat aaaggcgcca
    80401 aggactctct gcaggaacta ccttacaggt cacctccacc tccaaaagag gcagggaaac
    80461 ggcaggataa ccgtaaacga ccgcatgttc ccctattaaa attatcttac tatgtgcctg
    80521 accgacacca actttttttg tcattttttc cttttactag acgaaaaaac gtcttatttt
    80581 tcatacaagt attaattctt tcctatctat tttattatat tttcacaaaa aaagcgattg
    80641 tttccattca caatcgcttc tttcattacc gaacccattc accattataa ttgacagaat
    80701 agccatctac aatcgtattc actgccaagg cacctgagct ataagcgtag taccatctgc
    80761 cattgacctg gaaccaacct gtcgtcatag aacgatgaaa gaaactccat accattaagt
    80821 aaagaggaaa gtcatgaggg agcatgcgtc attgacaacc tattttagtg acgtacaaag
    80881 tttcattaac aagtactcgt ttcggccatt tataggtgcg gtgtttgcag aaatagggtt
    80941 caatcttcgc ccattcttga tcgtttaaat cagtatcata tgctttgcgt gtcataactc
    81001 tagtttaaca tttttttgtg aatacaggtt ctaaataatc gaccacgaaa atttcttaag
    81061 tggaaaacgc cttatgaagt atgctacggg aaacttatgc acttaatttg acaactcaat
    81121 atgtaaaaat atatactata
//
LOCUS       DAVBOG010000002        69961 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.002, whole genome shotgun sequence.
ACCESSION   DAVBOG010000002 DAVBOG010000000
VERSION     DAVBOG010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 69961)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69961)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69961
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.002"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            624..1265
                     /locus_tag="VQ865_000084"
     CDS             624..1265
                     /locus_tag="VQ865_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3134517.1"
                     /translation="MTIESGQRIALVGQPGSGKSTLSKIPSGLYKIDTGKVLFDGVNI
                     NQIDKKILSQNLGVVPQDSFLLNRSILDNITLKHEVTSQKIEEVCKAVQIYDEIMAMP
                     MKFNTIISEMGSNISGGQRQRIALARALINNPSIVILDEATSALDTINEERITKYIKS
                     QGCTQIIVAHRLSTIKDADIIVVMKGGKIVESGNHKYLMDLGGEYYSLYTKRK"
     gene            1278..1448
                     /locus_tag="VQ865_000085"
     CDS             1278..1448
                     /locus_tag="VQ865_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134518.1"
                     /translation="MKKENEYVILTTASLGVMIGIVFAIFLDFPVEYGISLGLLNGIV
                     LGSLIVYKNNKN"
     gene            complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ865_000086"
     CDS             complement(1944..3290)
                     /gene="gdhA"
                     /locus_tag="VQ865_000086"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HET3134519.1"
                     /translation="MTSAKEYIQSVFETVKARNGHEAEFLQAVEEFFNTLEPVFEKHP
                     EYIEENILARITEPERVVSFRVPWVDRDGKIQVNRGYRVQFNSAVGPYKGGLRFHPTV
                     NQGILKFLGFEQIFKNVLTGLPIGGGKGGSDFDPKGKTDAEVMRFCQSFMTELQKHIG
                     PSLDVPAGDIGVGGREIGYLYGQYKRLNQFDAGVLTGKPLGFGGSLIRPEATGYGLVY
                     YTEEMLKANGNSFAGKKVVISGSGNVAQYALQKATELGATVISVSDSNGYVIDENGID
                     FDLLVDVKEKRRARLTEYAAEKATATYHEGTVWTYAGNYDIALPCATQNEINGEAAKR
                     LVAQGIICVSEGANMPSDLDAIKVYKENGILYGPAKAANAGGVAVSALEMSQNSLRLS
                     WTREEVDDRLKDIMTNIFNTAKTTSETYGLDKDYLAGANIAAFENVANAMIAQGIV"
     gene            3822..4278
                     /locus_tag="VQ865_000087"
                     /pseudo
     CDS             3822..4278
                     /locus_tag="VQ865_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix domain-containing
                     protein"
     gene            4281..5293
                     /locus_tag="VQ865_000088"
                     /pseudo
     CDS             4281..5293
                     /locus_tag="VQ865_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182321.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Dyp-type peroxidase"
     gene            5268..5846
                     /locus_tag="VQ865_000089"
     CDS             5268..5846
                     /locus_tag="VQ865_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron permease"
                     /protein_id="HET3134520.1"
                     /translation="MVRNYWKARSWLLVLALSFLILSPVGAQESLSSYFVKITDTSKA
                     VKNGNQSEAQKLVQEMASDFERVENKDSEVGKIVKEKLALSGDITEAKLTEISSALLA
                     FEKEQNPVDLDAEKEKLVNRLSPRFETLEQAIASKDLEKVREAFKKMNSTWTINESVV
                     RDNSIAHYGRVETAISFLPSSMETEPTDESGT"
     gene            complement(5903..6187)
                     /locus_tag="VQ865_000090"
     CDS             complement(5903..6187)
                     /locus_tag="VQ865_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HET3134521.1"
                     /translation="MARKETMAERKYCKMKKDIHPEYRPVVFMDTTTGYQFLSGSTKR
                     SNETVEFEGETYPLIRVEISSDSHPFYTGRQKFTQADGRVDRFNKKYGLK"
     gene            complement(6241..7176)
                     /locus_tag="VQ865_000091"
     CDS             complement(6241..7176)
                     /locus_tag="VQ865_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HET3134522.1"
                     /translation="MEICQQILEKIKEYDTIIIHRHMKPDPDALGSQVGLKALLEHHF
                     PEKTIKAVGFDEPTLTWMAEMDLVEDRAYQGALVIVCDTANTARIDDKRYSQGDFLIK
                     IDHHPNDDVYGDLSWVDTSSSSASEMITLFAQTTQLALADRDAELLFAGIVGDTGRFL
                     YPSTTARTLRLAAYLREHNFDFAALTRKMDTMSYKIAKLQGYIYDHLEVDENGAARVI
                     LSQEVLKQYNVTDAETAAIVSAPGRIDSVSLWGIFVEQADGHYRVRLRSKIHPINEIA
                     KEHDGGGHPLASGANSYSLEENEIIYQKLKNLLKN"
     gene            7280..7723
                     /locus_tag="VQ865_000092"
     CDS             7280..7723
                     /locus_tag="VQ865_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HET3134523.1"
                     /translation="MALAKIVFASMTGNTEEIADIVADKLRDLGLDVDVDECTTVDAS
                     DFLEADIAIVATYTYGDGELPDEMMDFYEDLADLNLNGKIYGVVGSGDTFYDEFCKAV
                     DDFDRVFVSTGAEKGSECVKVDLSAEEEDIERLEQFAEELVAKVG"
     gene            7839..8105
                     /locus_tag="VQ865_000093"
     CDS             7839..8105
                     /locus_tag="VQ865_000093"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HET3134524.1"
                     /translation="MDLDIIRQEIDQIDDQIVKLLEERMHLVEGVVAYKKASGKPILD
                     TKREEVIFEKVGSRVEDKRYQETIVATFSDILKRSRDYQDQNIK"
     gene            8102..8476
                     /gene="crcB"
                     /locus_tag="VQ865_000094"
     CDS             8102..8476
                     /gene="crcB"
                     /locus_tag="VQ865_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3134525.1"
                     /translation="MKKEQFYPLGIFLAAMLGGLVRYLVSTWLPASPDFPWGTLFVNY
                     LGIFCLIYLVKGYLVYKGTSKGLILALGTGFCGGLTTFSSLMLDTVKLLDTGRYLSLI
                     LYLLLSIGGGLLLAYYLGRKKW"
     gene            8470..8799
                     /gene="crcB"
                     /locus_tag="VQ865_000095"
     CDS             8470..8799
                     /gene="crcB"
                     /locus_tag="VQ865_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HET3134526.1"
                     /translation="MVIVYLAIACGLGALVRYFFSRYNQVSKLPLGTLIANLLGCFLI
                     GVFYNHVESKEVYAILATGFCGGLTTFSTLNDELQRLLSDKKVFYSYLTLTYIGGLVA
                     IFLGILL"
     gene            8918..9265
                     /gene="rplS"
                     /locus_tag="VQ865_000096"
     CDS             8918..9265
                     /gene="rplS"
                     /locus_tag="VQ865_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HET3134527.1"
                     /translation="MNPLIQSLTEGQLRTDIPSFRPGDTVRVHAKVVEGNRERIQIFE
                     GVVIARKGAGISENYTVRKISNGVGVERIFPIHTPRVEKIEVVRYGKVRRAKLYYLRA
                     LQGKAARIKEIRR"
     gene            9307..9378
                     /locus_tag="VQ865_000097"
     tRNA            9307..9378
                     /locus_tag="VQ865_000097"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:9340..9342,aa:Arg,seq:cct)
     gene            complement(9544..10542)
                     /locus_tag="VQ865_000098"
     CDS             complement(9544..10542)
                     /locus_tag="VQ865_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001008999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAP domain-containing protein"
                     /protein_id="HET3134528.1"
                     /translation="MNFFSKLFNLKQNNHNRDTNSDCNNFYLNKLECGLTPGQLILID
                     WTQKTGRNYNFPRYFKYSLQIDPESTHNQLYKLGYFTKNKTLSYLKVVELKTILSKHN
                     LATSGKKAELITRIINNINVDKLDIPFEFKLTKEAQNLIIEHSDYIKAYYDKDISMED
                     YCKEKNNISFKATFGDIKWSLLNKQAHRNTVSGDFGCLSNTRKAQGRHLEQEGNIKHA
                     LIYYIESLIITISGLENNFSATDYPVYYPDSIPDYSLKHIQTLMESLSDDDYDFAFDE
                     ALFRFSILNANHFLSKEDIDYLRVNLPRSTAEEINNYLKKYECYSPLNNLELDDFE"
     gene            complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ865_000099"
     CDS             complement(10585..11391)
                     /gene="yidA"
                     /locus_tag="VQ865_000099"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HET3134529.1"
                     /translation="MSIKLIAVDIDGTLVNSQKEITPEVFSAIQDAKEAGVKVVIATG
                     RPIAGVAKLLDDLQLRDQGDYVVTFNGALVQETATGHEIISESLTYEDYLDMEFLSRK
                     LGVHMHAITKDGIYTANRNIGTYTVHESTLVSMPIFYRTPEEMAGKEIVKCMFIDEPE
                     ILDAAIEKIPAEFYEHYSINKSAPFYLELLKKNVDKGSAITHLAEKLGLTKDETMAIG
                     DEENDRAMLEVVGNPVVMENGNPEIKKIAKYITKSNDESGVAHAIRTWVL"
     gene            complement(11404..12708)
                     /locus_tag="VQ865_000100"
     CDS             complement(11404..12708)
                     /locus_tag="VQ865_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HET3134530.1"
                     /translation="MNEKVFRDPVHNYIHVINQIIYDLINTKEFQRLRRIKQLGTSSY
                     TFHGGEHSRFSHCLGVYEIARRITEIFEEKYPEEWNPAESLLTMIAALLHDLGHGAYS
                     HTFEHLFDTDHEAITQEIIQSPETEIHQVLLQVAPDFPEKVASVIDHTYPNKQVVQLI
                     SSQIDADRMDYLLRDSYFTGASYGEFDLTRILRVIRPIENGIAFQRNGMHAIEDYVLS
                     RYQMYMQVYFHPATRAMEVLLQNLLKRAKELYPKDKDFFARTSPHLLPFFEKNVTLSD
                     YLALDDGVMNTYFQLWMTSPDKILADLSQRFVNRKVFKSITFSQEDQDQLASMRKLVE
                     DIGFDPDYYTAIHKNFDLPYDIYRPESENPRTQIEILQKNGELAELSSLSPIVQSLAG
                     SRHGDNRFYFPKEMLDQNSIFASITQQFLYLIENDHFTPNKN"
     gene            12780..13157
                     /locus_tag="VQ865_000101"
     CDS             12780..13157
                     /locus_tag="VQ865_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HET3134531.1"
                     /translation="MKIRMRNTIQFDEQLEVIDQLYDVEVHEKGDYSYLLFYNEEKEK
                     VVIKFHGQELVMSRFSNPKTIMRFLKNSDSLAYIPTPMGMQEFIIQTSHYQVDRQKIE
                     LDYQLQNQEGHPFASYQLEITWG"
     gene            13248..13580
                     /locus_tag="VQ865_000102"
     CDS             13248..13580
                     /locus_tag="VQ865_000102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009660419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HET3134532.1"
                     /translation="MEIEKTNRMNALFEFYAALLTDKQMNYIELYYADDYSLAEIAEE
                     FGVSRQAVYDNIKRTEKILEDYEMKLHMYSDYIVRSQIFDQILERYPKDNFLQEQIEI
                     LTSIDNRE"
     gene            13592..15163
                     /gene="ffh"
                     /locus_tag="VQ865_000103"
     CDS             13592..15163
                     /gene="ffh"
                     /locus_tag="VQ865_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HET3134533.1"
                     /translation="MAFESLTERLQNVFKNLRKKGKISESDVQEATKEIRLALLEADV
                     ALPVVKDFIKKVRERAVGHEVIDTLNPAQQIIKIVDEELTAVLGSDTAEIIKSPKIPT
                     IIMMVGLQGAGKTTFAGKLANKLKKEENARPLMIAADIYRPAAIDQLKTLGQQIDVPV
                     FALGTEVPAVEIVRQGLEQAQTNHNDYVLIDTAGRLQIDELLMNELRDVKALAQPNEI
                     LLVVDAMIGQEAANVAREFNAQLEVTGVILTKIDGDTRGGAALSVRHITGKPIKFTGT
                     GEKITDIETFHPDRMSSRILGMGDMLTLIEKASQEYDEQKALEMAEKMRENTFDFNDF
                     IDQLDQVQNMGPMEDLLKMIPGMANNPALQNMKVDERQIARKRAIVSSMTPEERENPN
                     LLNPSRRRRIAAGSGNTFVEVNKFIKDFNQAKQLMQGVMSGDMNKMMKQMGINPNNLP
                     KNMPNMGGMDMSALEGMMGQGGMPDLSALGGAGMPDMSQMFGGGLKGKIGEFAMKQSM
                     KRMANKMKKAKKKRK"
     gene            complement(15358..16641)
                     /locus_tag="VQ865_000104"
     CDS             complement(15358..16641)
                     /locus_tag="VQ865_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007554578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HET3134534.1"
                     /translation="MKQESTVDLLLDVDQRPSDGKGILLSFQHVFAMFGATILVPLIL
                     GMPVSVALFASGVGTLIYMIATGFKVPVYLGSSFAFITAMSLAMKEMGGDVSAAQTGV
                     ILTGLVYVLVATSIRFVGTKWIDKLLPPIIIGPMIIVIGLGLAGSAVTNAGLVADGNW
                     KNALVAVVTFLIAAFINTKGKGFLRIIPFLFAIIGGYLFALTLGLVDFTPVLKANWFE
                     IPGFYLPFSTGGAFKEYNLYFGPEAIAILPIAIVTISEHIGDHTVLGQICGRQFLKEP
                     GLHRTLLGDGIATSVSAFLGGPANTTYGENTGVIGMTRIASVSVIRNAAFIAIALSFL
                     GKFTALISTIPNAVLGGMSILLYGVIASNGLKVLIKERVDFAQMRNLIIASAMLVLGL
                     GGAILKLGPVTLSGTALSAMTGIILNLILPYENKD"
     gene            complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ865_000105"
     CDS             complement(16895..17608)
                     /gene="rsmG"
                     /locus_tag="VQ865_000105"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HET3134535.1"
                     /translation="MKPETFYNLLAEQNLPLSNQQKEQFERYFELLVEWNEKINLTAI
                     TDKEEVYLKHFYDSIAPILQGLIPNETIKLLDIGAGAGFPSLPMKILYPELDVTIIDS
                     LNKRINFLQLLAQELDLNGVHFYHGRAEDFAQDKNFRAQYDFVTARAVARMQVLSELT
                     IPYLKVGGKLLALKASNAPEELLEAKNALNLLFSKVEDNLSYALPNRDPRYITVVEKK
                     KETPNKYPRKAGMPNKRPL"
     gene            17702..18262
                     /locus_tag="VQ865_000106"
     CDS             17702..18262
                     /locus_tag="VQ865_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LemA family protein"
                     /protein_id="HET3134536.1"
                     /translation="MTWIILGVIALIVIFVIVSYNGLVKNRMQTKEAWSQIDVQLKRR
                     NDLLPNLIETVKGYAKYEGSTLEKVAELRNQVAAATSPAEAMKASDALTRQVSGIFAV
                     AESYPDLKASANFVKLQEELTNTENKISYSRQLYNSVVSNYNVKLETFPSNIIAGMFG
                     FKAADFLQTPEEEKSVPKVDFSGLGD"
     gene            18264..19163
                     /gene="htpX"
                     /locus_tag="VQ865_000107"
     CDS             18264..19163
                     /gene="htpX"
                     /locus_tag="VQ865_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metalloprotease HtpX"
                     /protein_id="HET3134537.1"
                     /translation="MLFDQIASNKRKTWILLLVFFLLLALVGYAVGYLFIRSGLGGLV
                     IALIIGFIYALSMIFQSTEIVMSMNGAREVDEQTAPDLYHVVEDMALVAQIPMPRVFI
                     IDDPALNAFATGSNPQNAAVAATSGLLAIMNREELEAVMGHEVSHIRNYDIRISTIAV
                     ALASAITMLSGMAGRMMWWGGAGRRRSDDDRDGNGLEIIMLVVSLLAIVLAPLAATLV
                     QLAISRQREFLADASSVELTRNPQGMINALDKLDNSKPMSRHVDDASSALYINDPKKG
                     GGFQKLFYTHPPISERIERLKQM"
     gene            complement(19207..20766)
                     /locus_tag="VQ865_000108"
     CDS             complement(19207..20766)
                     /locus_tag="VQ865_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3134538.1"
                     /translation="MHYEHSRKGNSMIKINHLTITQNKDLRDLVSDLSMTIQDGEKVA
                     IIGEEGNGKSTLLKTLMGEALSDFTIKGNIQSDYQSLAYIPQKLPEELKKKTLHDYFF
                     LDSIDLDYSILYRLAEELHFDSNRFASDQEIGNLSGGEALKIQLIHELAKPFEILFLD
                     EPSNDLDLETVDWLKGQIQKTRQTVIFISHDEDFLSETADTIVHLRLVKHRKEAETLV
                     EHLDYDSYSEQRKANFAKQSQQAANNQRAYDKTMEKHRRVKQNVETALRATKDSTAGR
                     LLAKKMKTVLSQEKRYEKAAQSMTQKPLEEEQIQLFFSDIQPLPASKVLVQLEKENLS
                     IDDRVLVQKLQLTVRGQEKIGIIGPNGVGKSTLLAKLKQLLNDKREISLGFMPQDYHK
                     KLQLDLSPIAYISKTGEKEELQKIHSHLASLNFSYPEMQHQIRSLSGGQQGKLLLLDL
                     VLRKPNFLLLDEPTRNFSPTSQPQIRKLFATYPGGLITVSHDRRFLKEVCSIIYRMTE
                     HGLELVNLEDL"
     gene            21491..22033
                     /locus_tag="VQ865_000109"
     CDS             21491..22033
                     /locus_tag="VQ865_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HET3134539.1"
                     /translation="MKLNIQEIRKQSEGLNFEQTLDLVDDLRARNQEILDVKDILAVG
                     KVQYEDRMYFLDYQLSYTIVLASSRSMEPVELVESYPVTEVFMEGATNQLDQEVLDDD
                     LVLPIENGELDLAESVSDNILLNIPIKVLTAEEEAGQGFVSGNDWQIMTEEEYQAQQA
                     VKKEENSPFAGLQGLFDGDE"
     gene            22033..22662
                     /gene="nth"
                     /locus_tag="VQ865_000110"
     CDS             22033..22662
                     /gene="nth"
                     /locus_tag="VQ865_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HET3134540.1"
                     /translation="MVLSKKRARKVLEEIIALFPDAKPSLDFTNHFELLVAVMLSAQT
                     TDAAVNKATPGLFVAFPTPQAMSVATESEIASHISRLGLYRNKAKFLKKCAQQLLDDF
                     DGQVPQTREELESLAGVGRKTANVVMSVGFGIPAFAVDTHVERICKHHDIVKKSATPL
                     EVEKRVMDILPPEQWLAAHQAMIYFGRAICHPKNPECDQYPQLYDFSNL"
     gene            22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ865_000111"
     CDS             22873..23394
                     /gene="pyrR"
                     /locus_tag="VQ865_000111"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HET3134541.1"
                     /translation="MKTKEVVDELTVKRAITRITYEIIERNKDLNKIVLAGIKTRGVF
                     IAHRIQERLKQLENLSVPVVELDTKPFRDDVKSGEDTSLVSVDVTDREVILVDDVLYT
                     GRTIRAAIDNIVGHGRPARVSLAVLVDRGHRELPIRPDYVGKNIPTSRSEEIIVEMTE
                     LDDQDRVLITEEA"
     gene            23413..24336
                     /locus_tag="VQ865_000112"
     CDS             23413..24336
                     /locus_tag="VQ865_000112"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001293822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HET3134542.1"
                     /translation="MSENQQALNHVVSMEDLTVDQVMKLIKRGIEFKNGAQLPYEDHP
                     IVSNLFFEDSTRTHKSFEVAEIKLGLERLDFDVKTSSVNKGETLYDTILTLSALGVDV
                     CVIRHPEVDYYRELIASPTITTSIINGGDGSGQHPSQSLLDLMTIYEEFGHFEGLKVA
                     IAGDLDHSRVAKSNMQILKRLGSELFFAGPEEWRSQEFADYGQFVTIDEIIDQVDVMM
                     FLRVQHERHDSGAVFSKEDYHAQHGLTQERYDRLKETAILMHPAPINRDVEIADHLVE
                     APKSRIVQQMTNGVFVRMAILESVLASRNAN"
     gene            24386..25465
                     /gene="carA"
                     /locus_tag="VQ865_000113"
     CDS             24386..25465
                     /gene="carA"
                     /locus_tag="VQ865_000113"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HET3134543.1"
                     /translation="MTKRILVLEDGTVFEGKAFGADIDVTGEIVFNTGMTGYQESITD
                     QSYNGQILTFTYPLVGNYGINRDDYESIIPTCKGVVVFEKARRASNWRNQMTLDEFLK
                     AKKIPGISGIDTRALTKIIRKHGTMRATLTHVGDSMDHVTDQLQATVLPTDNIKQVST
                     KTSYPAPGVGLSVVLVDFGLKHSILRELSKRNCNVTVVPYSTTAEEILHLNPDGVMLS
                     NGPGNPEDVPQALDMIRGVQGKIPIFGICMGHQLFAMANGAKTYKMKFGHRGFNHAVR
                     EIATGRVDFTSQNHGYAVSREDLPEHLIITHEEINDKSVEGVRHRYQPAFSVQYHPDA
                     APGPHDASYLFDEFIEMMEVFKQSN"
     gene            25778..28954
                     /gene="carB"
                     /locus_tag="VQ865_000114"
     CDS             25778..28954
                     /gene="carB"
                     /locus_tag="VQ865_000114"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HET3134544.1"
                     /translation="MPKRTDIQKIMVIGSGPIIIGQAAEFDYAGTQACLSLKEEGYEV
                     VLVNSNPATIMTDKEIADKVYIEPITLEFVTRILRKERPDALLPTLGGQTGLNMAMEL
                     SKNGILDELSVELLGTKLSAIDQAEDRDLFKQLMEELEQPIPESEIVNTVEEAVAFAA
                     TIGYPVIVRPAFTLGGTGGGMCANEKELREITENGLKLSPVTQCLIERSIAGFKEIEY
                     EVMRDSADNALVVCNMENFDPVGIHTGDSIVFAPAQTMSDYENQMLRDASLSIIRALK
                     IEGGCNVQLALDPNSFKYYVIEVNPRVSRSSALASKATGYPIAKLAAKIAVGLTLDEV
                     INPVTGSTYAMFEPALDYVVAKIPRFPFDKFEKGERRLGTQMKATGEVMAIGRNIEES
                     LLKACRSLEIGVHHNEIPELAAVSDDALIEKVVKAQDDRLFYVSEAIRRGYTPEEIAE
                     LTKIDIFYLDKLLHIFEIEQELGAHPQDLEVLKTAKLNGFSDRKIAELWGTTDDKVRQ
                     LRLENKIVPVYKMVDTCAAEFDSETPYFYSTYGWENESIRSDKESVLVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQAAGYEAIIMNSNPETVSTDFSVSDKLYFEPLTFEDVMNVIDL
                     EQPKGVIVQFGGQTAINLAEPLAKAGVTILGTQVADLDRAEDRDLFEQALKELDIPQP
                     PGQTATNEEEAALAARKIGFPVLVRPSYVLGGRAMEIVENEEDLRSYMRTAVKASPDH
                     PVLVDSYIVGQECEVDAISDGKDVLIPGIMEHIERAGVHSGDSMAVYPPQTLSQKVQE
                     TIADYTKRLAIGLHCLGMMNIQFVIKDEKVYVIEVNPRASRTVPFLSKVTNIPMAQVA
                     TKLILGQSLSELGYQNGLYPESTRVHIKAPVFSFTKLAKVDSLLGPEMKSTGEVMGSD
                     ATLEKALYKAFEASYLHLPTFGNVVFTIADDAKEEALNLARRFQNIGYGILATEGTAA
                     FFASHGLQAQPVGKIGDDDKDIPSFVRKGRIQAIINTVGTKRTADEDGEQIRRSAIEH
                     GVPLFTALDTANAMLKVLESRSFVTEAI"
     gene            complement(29229..30038)
                     /locus_tag="VQ865_000115"
     CDS             complement(29229..30038)
                     /locus_tag="VQ865_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3134545.1"
                     /translation="MQYLEKKEIKEIQLALLDYIDETCKKHDIPYFLSYGTMLGAIRH
                     KGMIPWDDDIDISLYREDYERLLKIIEEENHPRYKVLSYDTSSWYFHNFASILDTSTV
                     IEDHVKYKRHDTSLFIDVFPIDRFTDLSIVDKSYKYVALRQLAYIKKSRAVHGDSKLK
                     DFLRLCSWYALRFVNPRYFYKKIDQLVKNAVTNIPQYEGGVGIGKEGMKEIFPVDTFK
                     ELILTEFEGRMLPVPKKYDQFLTQMYGDYMTPPSKEMQEWYSHSIKAYRKN"
     gene            complement(30040..30843)
                     /locus_tag="VQ865_000116"
     CDS             complement(30040..30843)
                     /locus_tag="VQ865_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3134546.1"
                     /translation="MKQLTIEDAKQIELEILDYIDTLCKKHNINYIINYGTLIGAVRH
                     EGFIPWDDDIDLSMPREDYQRFINIFQKEKSKYKLLSLETDKNYFNNFIKITDSTTKI
                     IDTRNTKTYESGIFIDIFPIDRFDDPKVIDTCYKLESFKLLSFSKHKNIVYKDSLLKD
                     WIRTAFWLLLRPVSPRYFANKIEKEIQKYSRENGQYMAFIPSKFKEKEVFPSGTFDKT
                     IDLPFENLSLPAPEKFDTILTQFYGDYMTLPPEEKRFYSHEFHAYKLED"
     gene            complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ865_000117"
     CDS             complement(30853..32340)
                     /gene="tacF"
                     /locus_tag="VQ865_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV teichoic acid flippase TacF"
                     /protein_id="HET3134547.1"
                     /translation="MKSIKLNALSYMGIRVLNIIFPILTGTYVARVLDRTDYGYFNSV
                     DTILSFFLPFATYGVYNYGLRAISNVKDNKKDLNRTFSSLFYLCIACTILTTAVYILA
                     YPLFFIDNPIVKKVYLVMGIQLIAQIFSIEWVNEALENYSFLFYKTAFIRILMLVSIF
                     LFVKNEHDIVVYTLVMSLSTLINYLISYFWIKRDIKLVKIHLSDFKPLFLPLTAMLVF
                     ANANMLFTFLDRLFLVKTGIDVNVSYYTIAQRIVTVIAGVVTGAIGVSVPRLSYYLGK
                     GDKEAYVSLVNRGSRIFNFFIIPLSFGLMVLGPNAILLYGSEKYIGGGILTSLFAFRT
                     IILALDTILGSQILFTNGYEKRITVYTVFAGLLNLGLNSLLFFNHIVVPEYYLLTTML
                     SETSLLVFYIIFIHRKQLIHLGHIFSYTVRYSLFSLSFVAIYFLINFVYPVDMVINLP
                     FLINTGLIVLLSAISYISLLVFTKDSIFYEFLNHVLALKNKFKKS"
     gene            32676..33383
                     /locus_tag="VQ865_000118"
     CDS             32676..33383
                     /locus_tag="VQ865_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HET3134548.1"
                     /translation="MIYAGILAGGTGTRMGISNLPKQFLELGDRPILIHTIEKFVLEP
                     SIEKIVVGVHGDWVSHAEDLVDKYLPLYKERIIITKGGADRNTSIKKIIEAIDAYRPL
                     TPEDIVVTHDSVRPFITLRMIQDNIQLAQNHDAVDTVVEAVDTIVESTNGQFITDIPN
                     RAHLYQGQTPQTFRCKDFMDLYGSLSDEEKEILTDACKIFVIKGKDVALAKGEYSNLK
                     ITTVTDLKIAKSMIEKD"
     gene            33388..34410
                     /locus_tag="VQ865_000119"
     CDS             33388..34410
                     /locus_tag="VQ865_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3134549.1"
                     /translation="MINQIYQLTKPKFINVKYQEEAIDQENHILIRPNYMAVCHADQR
                     YYQGKRDPKILNKKLPMAMIHESCGTVISDPTGTYEVGQKVVMIPNQSPMQSDEEFYE
                     NYMTGTHFLSSGFDGFMREFVSLPKDRVVAYDAIEDTVAAITEFVSVGMHAMNRLLTL
                     AHSKRERIAVIGDGSLAFVVANIINYTLPESEIVVIGRHWEKLELFSFAKECYITDNI
                     PEELAFDHAFECCGGDGTGPAINDLIRYIRPQGTILMMGVSEYKVNLNTRDALEKGLI
                     LVGSSRSGRIDFKNAIQMMEVKKFANRLKNILYLEEPVREIKDIHRVFATDLNTAFKT
                     VFKWEV"
     gene            34427..35296
                     /gene="licA"
                     /locus_tag="VQ865_000120"
     CDS             34427..35296
                     /gene="licA"
                     /locus_tag="VQ865_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000411210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline kinase LicA"
                     /protein_id="HET3134550.1"
                     /translation="MEKIIKEKISSLLSQEEEVLSVEQLGGMTNQNYLVKTTNKQYIV
                     KFFGKGTEKLINRQDEKYNLELLKDLGLDVKNYLFDIEAGIKVNEYIESAITLDSTSI
                     KTKFDKIAPILQTIHTSAKELRGEFAPFEEIKKYESLVEEQIPYANYESVRNAVFSLE
                     KRLADLGVDRKSCHIDLVPENFIESPQGRLYLIDWEYSSMNDPMWDLAALFLESEFTS
                     QEEETFLSHYESDQTPVSHEKIAIYKILQDTIWSLWTVYKEEQGEDFGDYGVNRYQRA
                     VKGLASYGGSDEK"
     gene            35286..36164
                     /locus_tag="VQ865_000121"
     CDS             35286..36164
                     /locus_tag="VQ865_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HET3134551.1"
                     /translation="MKSKNGVPFGLLSGIFWGLGLTVSAYIFSIFTDLSPFVVAAAHD
                     FLSIFILLAFLLVKEGKVRLSIFLNIRNVSVIIGALLAGPIGMQANLYAVKYIGSSLA
                     SSVSAIYPAISVLLAFFFLKHKISKNTVFGIVLIIGGIIAQTYKVEQVNSFYIGILCA
                     LVCAIAWGSESVLSSFAMESELSEIEALLIRQVTSFLSYLVIVLFSHQSFTAVANGQL
                     LGLMIVFAAFDMISYLAYYIAINRLQPAKATGLNVSYVVWTVLFAVVFLGAPLDMLTI
                     MTSLVVIAGVYIIIKE"
     gene            36176..36865
                     /locus_tag="VQ865_000122"
     CDS             36176..36865
                     /locus_tag="VQ865_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NTP transferase domain-containing protein"
                     /protein_id="HET3134552.1"
                     /translation="MKAIILAAGLGTRLRPMTENTPKALVQVNQKPLIEYQIEFLKEK
                     GINDIIIIVGYLKEQFDYLKEKYGVRLVFNDKYADYNNFYSLYLVKEELANSYVIDAD
                     NYLFKNMFRNDLTRSTYFSVYREDCTNEWFLVYGDDYKVQNIIVDSKAGRILSGVSFW
                     DAPTAEKIVSFIDKAYASGEFVDLYWDNMVKDNIKELDVYVEELEGNSIYEIDSVQDY
                     HKLEEILKNEN"
     gene            36963..37811
                     /gene="dprA"
                     /locus_tag="VQ865_000123"
     CDS             36963..37811
                     /gene="dprA"
                     /locus_tag="VQ865_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HET3134553.1"
                     /translation="MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADIS
                     GCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDCYPWDLSEIYDAPVLLFYKGNLD
                     LLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
                     TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRG
                     VIVAEAKMRSGSLITCERAMEEGRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDV
                     LAEFEF"
     gene            38695..39738
                     /locus_tag="VQ865_000124"
     CDS             38695..39738
                     /locus_tag="VQ865_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00341 family protein"
                     /protein_id="HET3134554.1"
                     /translation="MTNNKLYSLIEFRNKIYEELELSRSDLAILLCAMLIASIGLNMD
                     STPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLS
                     PISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCT
                     VGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRIL
                     LLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTIS
                     GNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKEAKEK
                     EKANKFDTESEEQ"
     gene            39905..41992
                     /gene="topA"
                     /locus_tag="VQ865_000125"
     CDS             39905..41992
                     /gene="topA"
                     /locus_tag="VQ865_000125"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HET3134555.1"
                     /translation="MATATKKKKSTVKKNLVIVESPAKAKTIEKYLGRNYKVLASVGH
                     IRDLKKSSMSVDIENNYEPQYINIRGKGPLINDLKKEAKKANKVFLASDPDREGEAIS
                     WHLAHILNLDENDANRVVFNEITKDAVKNAFKEPRKIDMDLVDAQQARRILDRLVGYS
                     ISPILWKKVKKGLSAGRVQSIALKLIIDRENEINAFQPEEYWTVDAVFKKGTKQFHAS
                     FYGVDGKKMKLTSNDEVKEVLSRLTSKDFSVDQVDKKERKRNAPLPYTTSSMQMDAAN
                     KINFRTRKTMMVAQQLYEGINIGSGVQGLITYMRTDSTRISPVAQNEAASFITDRFGS
                     KYSKHGSKVKNASGAQDAHEAIRPSSVFNTPESIAKYLDKDQLKLYTLIWNRFVASQM
                     TAAVFDTMAVKLSQKGVQFAANGSQVKFDGYLAIYNDSDKNKMLPDMAVGDVVKQVNS
                     KPEQHFTQPPARYSEATLIKTLEENGVGRPSTYAPTIETIQKRYYVRLAAKRFEPTEL
                     GEIVNKLIVEYFPDIVNVTFTAEMEGKLDDVEVGKEQWRRVIDAFYKPFSKEVAKAEE
                     EMEKIQIKDEPAGFDCEVCGSPMVIKLGRFGKFYACSNFPDCRHTQAIVKEIGVECPS
                     CHQGQIIERKTKRNRLFYGCNRYPECEFTSWDKPVGRDCPKCGNFLMEKKVRGGGKQV
                     VCSKGDYEEEKIK"
     gene            42098..42457
                     /locus_tag="VQ865_000126"
     CDS             42098..42457
                     /locus_tag="VQ865_000126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaN family protein"
                     /protein_id="HET3134556.1"
                     /translation="MRLIYLIIGFLSLALAIVGVVLPLLPTTPFLLLSIACFSRSSKR
                     FEDWLYHTKLYQTYVADFRETKSITRERKKKIIVSIYVLMGISIYFAPLLPVKIGLGA
                     LTIFITYYLFKVIPDKE"
     gene            42550..43182
                     /locus_tag="VQ865_000127"
     CDS             42550..43182
                     /locus_tag="VQ865_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HET3134557.1"
                     /translation="MIYEFCAENVTLLEKAMQAGARRIELCDNLAVGGTTPSYGVTKA
                     AVELAANYDTTIMTMIRPRGGDFVYNDLEIAIMLEDIRLTAQAGSQGVVFGTLTADKK
                     LDKPNLEKLIAASKGMEIVFHMAFDELSDEDQPEAIDWLSQAGVTRILTRAGVSGDSL
                     EKRFVHYHRILEYAKGKIEILPGGGIDLENRQTFIDQVGVTQLHGTKVVF"
     gene            43226..43882
                     /locus_tag="VQ865_000128"
     CDS             43226..43882
                     /locus_tag="VQ865_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HET3134558.1"
                     /translation="MFEIFKSYQFNQEKAHDYGFIENSEVWTYSCQILQGDFVMTVSI
                     TADNVNFQVFDQETGDLYPHVHMESMRGSFVGNVREACLEILYQIRKACFDVQDFICH
                     QTKRIMTQVQEKYGNQLEYLWEKSPDTAVLRHEGNQKWYAVLMKISWNKLEKGREGQV
                     EAVNLKHDQVANLLSQKGIYPAFHMSKRYWISVSLDDTLSDEEVLELIEKSWNLTSKK
                     "
     gene            43901..44533
                     /locus_tag="VQ865_000129"
     CDS             43901..44533
                     /locus_tag="VQ865_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001010941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HET3134559.1"
                     /translation="MNFQLAEYSLLKKFSENIGFTTPEECGAIFKYLIENVKTDRQII
                     YSPHCHDDLGMAVANSLAAVKNGAGRVEGTINGIRERAENAALEEIAVALNIRQDYYQ
                     VETSIVLNETINTSEMVSRFSGIPVPKNKAVVGGNTFSHESGIHQDGVLKNPLTYEII
                     TPELVGVKIPLGKLSGRHAFVEKLRELALDFTEEDIKPLFAKFKALADKK"
     gene            44561..44995
                     /locus_tag="VQ865_000130"
     CDS             44561..44995
                     /locus_tag="VQ865_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase I"
                     /protein_id="HET3134560.1"
                     /translation="MVAGTMVENPEGFHFDDLQLQTHADNDIEALVSLANMDGEKVEF
                     NATGQGSVEAIFNAIDKFFNQSVRLVSYTIDAVTDGIDTQDRVLVTVENRDTETIFNA
                     AGLDFDVLKASAIVYINANTFVQKENAGEMGRSVSYHDMPSV"
     gene            45007..46044
                     /gene="leuB"
                     /locus_tag="VQ865_000131"
     CDS             45007..46044
                     /gene="leuB"
                     /locus_tag="VQ865_000131"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HET3134561.1"
                     /translation="MAKKIVALAGDGIGPEIMEVGLEVLEALAEKTGFDYEIDRRPFG
                     GADIDAAGPPLPDETLKASREADAILLAAIGSPQYDGAVVRPEQGLMALRKELNLYAN
                     IRPVKIFDSLKYLSPLKLERIAGVDFVVVRELTGGIYFGDHILEERNARDINDYSYEE
                     VERIIRKAFEIARNRRKILTSIDKQNVLATSKLWRKVAEEVAQDFPDVTLEHQLVDSA
                     AMLMITNPAKFDVIVTENLFGDILSDESSVLSGTLEVMPSASHSENGPSLYEPIHGSA
                     PDIAGQGIANPTSMILSVAMMLRDSFGRYEDAERIKRAVETSLAAGILTRDIGGQAST
                     KEMTEAIIARL"
     gene            46041..46310
                     /locus_tag="VQ865_000132"
     CDS             46041..46310
                     /locus_tag="VQ865_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HET3134562.1"
                     /translation="MKLDEKITLVLLIWNVIIFLIYGIDKFKARRRAWRIPEKILLIL
                     ALTCGGFGAWLAGITFHHKTRKWYFKTVWFLGMVTTLVALYFIWR"
     gene            46314..46673
                     /gene="leuD"
                     /locus_tag="VQ865_000133"
     CDS             46314..46673
                     /gene="leuD"
                     /locus_tag="VQ865_000133"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HET3134563.1"
                     /translation="MAGSSREHAAWALADYGFKVVIAGSFGDIHYNNELNNGLLPIVQ
                     PREVREKLAQLKPTDQVTVDLEQQKIISPVEEFTFEIDSEWKHKLLNSLDDIGITLQY
                     EELIVAYEKQRPAYWQD"
     gene            46835..47459
                     /locus_tag="VQ865_000134"
                     /pseudo
     CDS             46835..47459
                     /locus_tag="VQ865_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002276310.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="translation factor (SUA5)"
     gene            47622..49535
                     /locus_tag="VQ865_000135"
     CDS             47622..49535
                     /locus_tag="VQ865_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrB family protein"
                     /protein_id="HET3134564.1"
                     /translation="MNKRKVSLEDFYKWYSLNKEELLNKATVGEKFNDKLKEEFLQEW
                     PLDRILTMSIDEYVIGKGQQNKSLCYALEKGKYKNLFLGISGGSASKFGIYWNKKTNK
                     YKDQANNEISELDQRFSKLKSDLYEIIKEGIRFNFENPIFDMKRSTNEFIGRSAMVTK
                     LLCIYSGGDPFFGVNINSQKEFWNHFVSQTNQGGPYLQNHKIIELVSKTYPELEPSKL
                     GTMLFEYSKLFMENKEDNSTMDSSNNFRHQLTQSLLKSPNLILRGAPGTGKTYLAKEI
                     AKELTDGNEDQIGFVQFHPSYDYTDFVEGLRPVSNGDGAIEFRLQDGIFKDFCQKAKE
                     TQLIGGQDNFDEAWDSYLEYINVAEEKEYITKTSYLSVNSRQNLSVNYDSGVPGWSLP
                     SKYVYELYKDKNYNKQEYYKSGGKTVLETLRKRFGLKDYVSPTEIDTDKKFVFIIDEI
                     NRGEISKIFGELFFSIDPGYRGEKGSVSTQYANLHETDEKFYIPENVYIIGTMNDIDR
                     SVDTFDFAMRRRFRFVEVTAEGQVGMLDKELNIHAEEAKIRLRNLNAAIENVQELNSH
                     YHIGPSYFLKLKDVDFDYELLWSDYIKPLLEDYLRGSYDEVETLETLKKAFELTNNDQ
                     TGQQDTGDNDADY"
     gene            49522..50838
                     /locus_tag="VQ865_000136"
     CDS             49522..50838
                     /locus_tag="VQ865_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="McrC family protein"
                     /protein_id="HET3134565.1"
                     /translation="MRITDNQYKIIKEKFVEEYPKLSNLLLDRTLESLSQDERIFIFP
                     NDLTHTPDLDKDQKIFETVNQKIKTGNVIGFLGYGQERLTISSRFSDESNDHFLHYLL
                     NKVLHINLTSLDVALSREERLYQLLMYLFPKYLQAAIRKGLYKEYQRFSHNDSHVKGV
                     IDVRNHLKKNLPFTGNIAYTTREFTYDNPLMQLVRHTIEYIKNQKSIGQGVLDNLSTS
                     RENVSEIVRVTPSYKLADRAKIIRGNQSKPIRHAYFHEYRNLQELCLMILNQEKHGLG
                     YQDQKIYGILFDVAWLWEEYVYTLLPKGFVHPRNKDKTDGISVFSVGKRKVYPDFYDR
                     ERKIVLDAKYKKLELTEKGINREDLFQLISYSYILKAEKAGLIFPSMEQSVNSEIGKV
                     AGYGAQLKKWSIRIPQNASFYSTFCKMMENSEENFKAIIDEEVGRK"
     gene            51013..51999
                     /locus_tag="VQ865_000137"
     CDS             51013..51999
                     /locus_tag="VQ865_000137"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HET3134566.1"
                     /translation="MLNEFPIFDYEDIQLIPNKCVIKSRAEADTSVTLGNHTFKLPVV
                     PANMQTILDENVAEQLAKGGYFYIMHRFDEAGRIPFIKRMHDQGLIASISVGVKDYEY
                     DFVRQLKADAPEYITIDIAHGHADSVISMIQHIKKELPDTFVIAGNVGTPEAVRELEN
                     AGADATKVGIGPGKVCITKVKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIA
                     KSIRFGASMIMIGSLFAGHIESPGKTIEVDGEQFKEYYGSASQYQKGAYKNVEGKRIL
                     LPAKGHLQDTLTEMEQDLQSAISYAGGRQVADLKHVDYVIVKNSIWNGDASH"
     gene            52063..52134
                     /locus_tag="VQ865_000138"
     tRNA            52063..52134
                     /locus_tag="VQ865_000138"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:52096..52098,aa:Arg,seq:ccg)
     gene            52317..53015
                     /locus_tag="VQ865_000139"
     CDS             52317..53015
                     /locus_tag="VQ865_000139"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HET3134567.1"
                     /translation="MKELQTVLKNHFAIEFADKNLLETAFTHTSYANEHRLLKISHNE
                     RLEFLGDAVLQLLISEYLYKKYPKKPEGDLSKLRAMIVREESLAGFARDCQFNQFIKL
                     GKGEEKSGGRNRDTILGDAFEAFLGALLLDKDVAKVKEFIYQVIIPKVEAGEFEMITD
                     YKTHLQELLQVNGDVAIRYQVISETGPAHDKVFDVEVLVEGKSIGQGQGRSKKLAEQE
                     AAKNAVEKGLDSCI"
     gene            53006..56545
                     /gene="smc"
                     /locus_tag="VQ865_000140"
     CDS             53006..56545
                     /gene="smc"
                     /locus_tag="VQ865_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HET3134568.1"
                     /translation="MYLKEIEIQGFKSFADKTKVVFDQGVTAVVGPNGSGKSNITESL
                     RWALGESSVKSLRGGKMPDVIFAGTESRKPLNYASVVVTLDNHDGFIKDAGQEIRVER
                     HIYRSGDSEYKIDGKKVRLRDIHDLFLDTGLGRDSFSIISQGKVEEIFNSKPEERRAI
                     FEEAAGVLKYKTRRKETESKLQQTQDNLDRLEDIIYELDNQIKPLEKQAENARKFLDL
                     EGQRKAIYLDVLVAQIKENKAELESTEEELTQVQELLMSYYQKREKLEEENQTLKKQR
                     QDLQAEMAKDQGSLMDLTSLISDLERKLALSKLESEQVALNQQEAQARLAALEDKRNS
                     LSKEKSDKESSLALLEGNLVQNNQKLNRLEAELLAFSDDPDQMIELLRERFVALLQEE
                     ADVSNQLTRIENELENSRQLSQKQADQLEKLKEQLAIAKEKASQQKEELETAKEQVQK
                     LLADYQAIAKEQEEQKTSYQAQQSQLFDRLDSLKNKQARAQSLENILRNHSNFYAGVK
                     SVLQEKDRLGGIIGAVSEHLTFDVHYQTALEIALGASSQHIIVEDEESATKAIDFLKR
                     NRAGRATFLPLTTIKARTISSQNQDVIAVSPGFLGMADELVTFDTRLEAIFKNLLATT
                     AIFDTVEHARAAARQVRYQVRMVTLDGTELRTGGSYAGGANRQNNSIFIKPELEQLQK
                     EIAADEASLGSEEAALKTLQDQMATLTERLEAIKSQGEQARIQEQGLSLAYQQTSQQV
                     EELETLWKLQEEEKDRLSDGDWQADKENCQERLAAIASDKQNLEAEIEEIKSNKNAIQ
                     ERYQNLQEELAQARLLKTELQGQKRYEVADIERLGKELDNLDFEQEEIQRLLQEKVDN
                     LEKVDTELLSQQAEESKTQKTNFQQGLIRKQFELDDIEGQLDDIASHLDQARQQNEEW
                     IRKQTRAEAKKEKVSERLRHLQSQLTDQYQISYTEALEKAHELENLNLAEQEVKDLEK
                     AIRSLGPVNIEAIDQYEEVHSRLDFLNSQRDDILSAKNLLLETITEMNDEVKERFKST
                     FEAIRESFKVTFKQMFGGGQADLILTEGDLLTAGVEISVQPQGKKIQSLNLMSGGEKA
                     LSALALLFSIIRVKTIPFVILDEVEAALDEANVKRFGDYLNRFDKDSQFIVVTHRKGT
                     MAAADSIYGVTMQESGVSKIVSVKLKDLESIEG"
     gene            56542..57336
                     /locus_tag="VQ865_000141"
     CDS             56542..57336
                     /locus_tag="VQ865_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3134569.1"
                     /translation="MTIKLVATDMDGTFLDGNGRFDMDRLKSLLASYKEKGIYFAVAS
                     GRGFLSLEKLFADVRDDIIFIAENGSLVEYQGQDLYEATMSRDFYLATFEKLKTSPYV
                     DINKLLLTGKKGSYVLDTVDETYLKVSQHYNENIQKVASLEDITDDIFKFTTNFTEET
                     LEAGEAWVNDNVPGVKAMTTGFESIDIVLDYVDKGVAIVELAKKLGITMDQVMAFGDN
                     LNDLHMMQVVGHPVAPENARPEILELAKTVIGHHKERSVIAYMEGL"
     gene            57336..58154
                     /locus_tag="VQ865_000142"
     CDS             57336..58154
                     /locus_tag="VQ865_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3134570.1"
                     /translation="MADIKLIALDLDGTLLTTDKRLTDRTKSTLKAARDRGIKVVLTT
                     GRPLKAMDFFLHELGTDGQEDEYTITFNGGLVQKNTGEILDKTVFSYDDVARLYEETE
                     KLSLPLDAISEGTVYQIQSDQESLYAKFNPALTFVPVDFEDLSSQMTYNKCVTAFAQE
                     PLDAAIQKISLELFDQYEIFKSREMLLEWSPKNVHKATGLAKLISHLGIDQSQVMACG
                     DEANDLSMIEWAGLGVAMQNAVPEVKVAANVVTPMTNDEEAVAWAIEEYVLKEN"
     gene            58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ865_000143"
     CDS             58158..59447
                     /gene="ftsY"
                     /locus_tag="VQ865_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HET3134571.1"
                     /translation="MGLFDRLFGKKEEPKIEEVVKEALENLDLSEDVDLTFTEADEVP
                     QEEAEVEIVEQAVFQEEEIQDTVEESQDSEPAVGVSQEEIEELPNSEELPEEEKLEHE
                     GTVEENNSEVLEPEAPQTEETVQEKYDRSLKKTRTGFGARLNAFFANFRSVDEEFFEE
                     LEELLIMSDVGVQVASNLTEELRYEAKLENAKKPDVLRRVIIEKLVELYEKDGSYDES
                     IHFQDNLTVMLFVGVNGVGKTTSIGKLAHRYKQAGKKVMLVAADTFRAGAVAQLAEWG
                     RRVDVPVVTGPEKADPASVVFDGMERAVAEGIDILMIDTAGRLQNKDNLMAELEKIGR
                     IIKRVVPEAPHETFLALDASTGQNALVQAKEFSKITPLTGIVLTKIDGTARGGVVLAI
                     REELNIPVKLIGFGEKIDDIGEFNSENFMKGLLEGLI"
     gene            complement(59491..60978)
                     /locus_tag="VQ865_000144"
     CDS             complement(59491..60978)
                     /locus_tag="VQ865_000144"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HET3134572.1"
                     /translation="MSSKVIVTIFGASGDLAKRKLYPSLFRLYQSGNLSKHFAVIGTA
                     RRPWSKEYFESVVVESILDLADSTEQAQEFASHFYYQSHDVNDSEHYIALRQLQAELN
                     EKYQAEHNKLFFLSMAPQFFGTIAKHLKSENIVDGKGFERLIVEKPFGTDYATASKLN
                     VELLATFDEEQIFRIDHYLGKEMIQSIFAVRFANLIFENVWNKDFIDNVQITFAERLG
                     VEERGGYYDQSGALRDMVQNHTLQLLSLLAMDKPASFTKDEIRAEKIKVFKNLYHPTD
                     EELKEHFIRGQYRSGKIDGMKYISYRSEPNVNPESTTETFTSGAFFVDSDRFRGVPFF
                     FRTGKRLTEKGTHVNIVFKQMDSIFGEPLAPNILTIYIQPTEGFSLSLNGKQVGEEFN
                     LAPNSLDYRTDATATGASPEPYEKLIYDVLNNNSTNFSHWDEVCASWKLIDRIEKLWA
                     ENGAPLHDYKAGSMGPQASFDLLEKFGAKWTWQPDIAYRQDGRFE"
     gene            complement(61127..61867)
                     /locus_tag="VQ865_000145"
     CDS             complement(61127..61867)
                     /locus_tag="VQ865_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3134573.1"
                     /translation="MAKLKIDVNDLHKYYGKNEVLKGITTKFYEGDVVCIIGPSGSGK
                     STFLRSLNLLEEVTSGHITVNGYDLTEKTTNVDHVRENIGMVFQHFNLFPHMSVLDNI
                     TFAPIEHKLMTKEEAEELGMELLEKVGLADKANANPDSLSGGQKQRVAIARGLAMNPD
                     IMLFDEPTSALDPEMVGDVLNVMKELAEQGMTMIIVTHEMGFARQVANRVIFTADGEF
                     LEDGTPDQIFDNPQHPRLKEFLDKVLNV"
     gene            complement(61867..64032)
                     /locus_tag="VQ865_000146"
     CDS             complement(61867..64032)
                     /locus_tag="VQ865_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HET3134574.1"
                     /translation="MKKKFLAFLLILFPIFSLGIAKAETIKIVSDTAYAPFEFKDSDQ
                     TYKGIDVDIINKVAEIKGWNIQMSYPGFDAAVNAVQAGQADAIMAGMTKTKEREKVFT
                     MSDTYYDTKVVIATTKSHKISKYDQLTGKTVGVKNGTAAQRFLETIKDKYGFTIKTFD
                     TGDLMNNSLSAGAIDAMMDDKPVIEYAINQGQDLHIEMDGEAVGSFAFGVKKGSKYEH
                     LVTEFNQALSEMKKDGSLDKIIKKWTASSSSAVPTTTTLAGLKAIPVKAKYIIASDSS
                     FAPFVFQNSSNQYTGIDMELIKAIAKDQGFEIEITNPGFDAAISAVQAGQADGIIAGM
                     SVTDARKATFDFSESYYTANTILGVKESSNIASYEDLKGKTVGVKNGTASQTFLTENQ
                     SKYGYKIKTFADGSSMYDSLNTGAIDAVMDDEPVLKYSISQGQKLKTPISGTPIGETA
                     FAVKKGANPELIEMFNNGLANLKANGEFQKILDKYLASESSTASTSTVDETTLWGLLQ
                     NNYKQLLSGLGITLALALISFAIAIVIGIIFGMFSVSPYKSLRVISEIFVDVIRGIPL
                     MILAAFIFWGIPNFIESITGQQSPINDFVAGTIALSLNAAAYIAEIVRGGIQAVPVGQ
                     MEASRSLGISYGKTMRKIILPQATKLMLPNFVNQFVIALKDTTIVSAIGLVELFQTGK
                     IIIARNYQSFKMYAILAIFYLVIITLLTRLAKRLEKRIR"
     gene            64205..65158
                     /locus_tag="VQ865_000147"
     CDS             64205..65158
                     /locus_tag="VQ865_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000792120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3134575.1"
                     /translation="MKNKRIFKDFQASKMSLNIYTSPLLAFVFVFIGEFVAFTLYGIG
                     LLALIGLARNFGEAGQNLATYLQTLHQSLTDKTSDFRLILGLLAFGFILNTVFRWTRK
                     VEKRPIRTLGFYRENFLSNLLKGFSLGLALFLLTLLGLVVLGQYRLESIHLNPYSLAF
                     VVFTIPFWILQGTAEEVVARAWLLPQLASRTNLKLAILISSLFFTLLHMGNSGLTPLS
                     LVNLFLFGVAMALYLLKTDTVWGVAGIHGAWNFAQGNLFGILVSGQPSGTSLMTFLPQ
                     GNQDWLSGGSFGIEGSIMTSLVLLLLIVYLANKLKKENERM"
     gene            65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ865_000148"
     CDS             65235..67223
                     /gene="uvrB"
                     /locus_tag="VQ865_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HET3134576.1"
                     /translation="MINHITDNQFKLVSKYQPSGDQPQAIEQLVDNIEGGEKAQILMG
                     ATGTGKTYTMSQVISKVNKPTLVIAHNKTLAGQLYGEFKEFFPENAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSALLERNDVIVVASVSCIYGLGSPKEYA
                     DSVVSLRPGLEISRDKLLNDLVDIQFERNDIDFQRGRFRVRGDVVEIFPASRDEHAFR
                     VEFFGDEIDRIREVEALTGQVLGEVDHLAIFPATHFVTNDDHMEVAVAKIQAELEEQL
                     AVFEKEGKLLEAQRLKQRTEYDIEMLREMGYTNGVENYSRHMDGRSEGEPPYTLLDFF
                     PDDFLIMIDESHMTIGQIKGMYNGDRSRKEMLVNYGFRLPSALDNRPLRREEFESHVH
                     QIVYVSATPGDYENEQTETVIEQIIRPTGLLDPEVEVRPTMGQIDDLLGEINARVEKN
                     ERTFITTLTKKMAEDLTDYFKEMGIKVKYMHSDIKTLERTEIIRDLRLGVFDVLVGIN
                     LLREGIDVPEVSLVAILDADKEGFLRNERGLIQTIGRAARNSEGHVIMYADTVTQSMQ
                     RAIDETARRRKIQMAYNEEHGIVPQTIKKEIRDLIAVTKAVAKEEDKEVDINSLNKQE
                     RKELVKKLEKQMQEAVEVLDFELAAQIRDMMLEVKALD"
     gene            67233..67796
                     /locus_tag="VQ865_000149"
     CDS             67233..67796
                     /locus_tag="VQ865_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134577.1"
                     /translation="MIYLRKLKKEDLMSLWEMAYSQLNPVWKQYDAPYYDDYQYFSNF
                     KEFELQKSESILSNSNRLGIFVDDKLVGTVSRYWVCKETRWMELGIGIYDKKFWNTGI
                     GKVAMLQWIDRTFQDYLELEHLGLTTWSGNLGMMKLAEKLRMKKEAHIPKVRYYQGKY
                     FDSIKYGILREDWEKINDGYYQINGNS"
     gene            67762..68250
                     /locus_tag="VQ865_000150"
     CDS             67762..68250
                     /locus_tag="VQ865_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134578.1"
                     /translation="MTVIIKSMETPEEIEGKSLVHWQTWREAYDDLLPAEFQETMTLE
                     RCRFFSQKYPENTLIAIGDLKVVGFISYGNFRDDTIQAGGIIALYVLKDYYGKGIAQK
                     LMKAALTALNHFSEIFLWVLKDNKRAIAFYQKMGFTFDGQEKILELGKPIKEKRMVFY
                     SK"
     gene            68324..68791
                     /locus_tag="VQ865_000151"
     CDS             68324..68791
                     /locus_tag="VQ865_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3134579.1"
                     /translation="MSRSQLTILTNICLIEDLETQRVVMQYRAPENNRWSGYAFPGGH
                     VENDEAFAESVIREIYEETGLTIQNPQLVGIKNWPLDTGGRYIVICYKATEFSGTLQS
                     SEEGEVSWVQKDQIPNLNLAYDMLPLMEMMEAPDKSEFFYPRRTEDDWEKKIF"
     gene            complement(68788..69303)
                     /locus_tag="VQ865_000152"
     CDS             complement(68788..69303)
                     /locus_tag="VQ865_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HET3134580.1"
                     /translation="MTKDRKQALLQLLKEAPKALNGQSLAEHFHVTRQVIVQDIAILR
                     ADGAPILSTNRGYIYKQIDTNPYVHKLFKVKHEVEEIGQELLAIVDNGGHVQNTLIDH
                     PVYGEIETLLKLSCRRDVQHFLEQVEHSDFRPLSELTDGIHYHLVEAETQQDLHYIEE
                     ALDQLGYLVKD"
     gene            complement(69315..69842)
                     /locus_tag="VQ865_000153"
     CDS             complement(69315..69842)
                     /locus_tag="VQ865_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3134581.1"
                     /translation="MNTRKKTQFMTMTALLTAIAILIPIVMPFKIVIPPASYTLGSHI
                     AIFIAMFLSPLMAVFVILASSFGFLMAGYPMVIVFRAFSHISFGALGALYLQKFPDTL
                     DKPKSSWVFNFVLAVVHALAEVLACVLFYATSGTNVENMFYVLFVLVGFGTIIHSMVD
                     YTLALAVYKVLRKRR"
BASE COUNT        21393 a        12502 c        15212 g        20854 t
ORIGIN      
        1 aaaagcgtcg ttaatgatgc attaaagaac agtcgagatg aaaaaatcat gtgacgcacc
       61 aagggaggag tctgcccttt tgaggaaatc tagcgaggaa aaacgatact ggaacagcag
      121 aaagtaaaac tgacctcatg aggaggaaga aagtggctca tgaggtcagg ggttttgtaa
      181 gttacatcta gttgagagag gtatgaatga tttgggttta atcagatggt ttacctcctt
      241 ttcatcggta ttcaccactt tttcaatagt aaagacgaga tggtcttgcg gcaagaaaga
      301 actgatttct agtggtaaag ttgtttgatt tgtgttatag tgaatatgca tgggatagcc
      361 cttctaaatg gtttattggg caattctatt ttaccaagac tatcgcaacc atgcaaaaaa
      421 gcaacggcaa atccgcttct tttttggaga taagagacta ttgtcccaga ctcttagtac
      481 tggttggagg atacgatgaa agatagttat tggttaaatt attttccgga gtatagttta
      541 gaaacgtttg aagtagaata gatattaagg acctatcttt ctcttattcc aaagactcag
      601 ctcttgtaat agaaaattta aatttgacta ttgagtcagg acagagaatt gcactagtcg
      661 gtcaaccggg gtcaggaaaa agtacattat caaaaatacc atcaggatta tataagattg
      721 atacaggaaa agttttattt gatggtgtaa atattaatca aatagataaa aaaatattaa
      781 gtcaaaattt aggagtagtt ccacaggatt cgtttttatt gaacagaagt attcttgata
      841 acataacttt aaagcacgaa gttacttcac aaaagataga ggaagtttgt aaagcagttc
      901 aaatctatga tgaaatcatg gctatgccga tgaaatttaa tactatcatc tcagagatgg
      961 gttcaaatat ttcaggtggt caaagacaac ggatagcact ggcacgtgca ttaataaata
     1021 atcctagtat tgtaatttta gatgaagcaa ctagtgcttt agacactatt aatgaggaaa
     1081 gaataacaaa gtatataaaa agtcagggct gtactcaaat aattgtagct catagattgt
     1141 caacgattaa ggatgcggat attattgttg taatgaaagg tggtaagatt gttgagtcag
     1201 gaaatcataa gtacttaatg gatcttggtg gagagtacta cagcttatat acaaaaagga
     1261 aatgaggtgt aaagaaaatg aagaaagaaa atgaatatgt aattttaaca acagcctcac
     1321 taggggtgat gattggaata gtgtttgcaa tttttttaga ttttccagtt gaatatggta
     1381 tttctttagg attgttgaat ggaatagtat tgggttcgct gattgtttac aaaaacaata
     1441 agaattaagc ataatttttt gctgtaaact aaggagtaga gatggctata gttgaaatta
     1501 taaatctaac aaaaagcttt aaagatattg aagttattca taacacttaa ataatagagc
     1561 aactacagta gtagcttaaa aacatgatta aatcgctatt cttaggagta gcgttttttc
     1621 tttttgttta atactctttg aaaatctctt caaaccacgt cagctttgcc ttgccgtact
     1681 caagtacagc ctgcgactcg cttcctagtt tgctctttga ttttcattga gtataaaaag
     1741 ggttaagtaa gtatagtaaa ttgaaataag atatgaacaa atcgattaga aaagtcaaat
     1801 taatttctag aaatatgtta gaaattggtt tgaattccgc aatcaatttg ttcagttttt
     1861 atttcattta attagaattt cccaactgtc taactcaact aaaaatcccc aatcgtagtg
     1921 attgaggatt aagcaaataa atcttaaaca ataccttggg caatcatagc gtttgctaca
     1981 ttttcaaagg cagcaatgtt agctcctgca aggtagtctt tatcaagacc gtatgtttct
     2041 gaagtcgttt tagctgtgtt gaagatgttt gtcatgatgt ctttgagacg gtcatcaact
     2101 tcttcacgag tccatgagag gcgaagactg ttttggctca tttcaagagc tgaaacggct
     2161 acaccaccag cgttggcagc ttttgcaggt ccgtataaga taccattttc tttgtaaact
     2221 ttgatggcat caaggtcgct cggcatgttg gcaccttcag atacacagat aatgccttga
     2281 gcaaccaaac gtttagctgc ttcaccgttg atttcgtttt gagtggcaca tggaagagca
     2341 atgtcatagt ttccagcgta agtccataca gtaccttcgt ggtaggttgc agttgctttt
     2401 tcagctgcat actcagtcaa acgagcacga cgtttttctt taacatcaac caaaagatcg
     2461 aagtcgatac cattttcatc gatgacataa ccatttgagt cagaaacaga aataacagtt
     2521 gcaccgagtt cagttgcttt ttgaagagca tattgagcaa cgttaccaga acctgaaata
     2581 acgactttct taccagcaaa gctgttaccg ttagctttga gcatttcttc agtatagtaa
     2641 accaaaccgt aaccagttgc ttctggacga atcaagctac caccaaatcc aagaggttta
     2701 ccagtcaaga caccagcatc aaattggtta agacgtttgt attgaccgta aaggtaacca
     2761 atttcacgtc caccaacacc gatatcacca gcaggtacgt caagtgatgg tccgatgtgt
     2821 ttttgcaatt cagtcatgaa gctttggcag aagcgcatca cttcagcatc tgttttacct
     2881 ttaggatcga agtctgatcc acctttacct ccaccgatag gaagtccagt caagacattt
     2941 ttaaagattt gttcaaatcc gaggaatttc aagatccctt ggtttacagt tgggtggaaa
     3001 cgaagtccac ctttgtatgg tccaacagct gagttgaatt gaacacggta accacggttt
     3061 acttgaattt ttccatcacg gtcaacccaa ggaacacgga aagaaaccac gcgctcaggc
     3121 tcagtaatac gtgccaagat attttcttcg atatactcag ggtgtttttc aaatacaggt
     3181 tctaaagtgt tgaaaaattc ttcaacagct tggaggaatt cagcctcgtg cccgttacga
     3241 gctttcacag tttcaaacac gctttggata tattctttag cagatgtcat atcgttctcc
     3301 ttttattgtc atattttatt acataagaca ttatagcaga attttttttc actgtaaaga
     3361 aaaaacagaa actttctaaa aattctttca attcagtttt ttggtttttt tgaaaataga
     3421 taaaaaaacg aacgtttttc ttggaaatat ctttctcaaa gacaaaatct taaagtatgc
     3481 tataagaaaa gaaaatgttt agcaattcag aaatcacttg ttaatttatc cgtgatatgt
     3541 tagatttgcc agtaaaacta tgaccatttt ggagaaaagc aatatttaga ctagactaaa
     3601 ataaaaaagt attatataat agtgatatga aatcaactaa agaagaaatc caaaccatca
     3661 aaacactttt aaaagactct cgtacagcta aatatcataa acgccttcaa atcgttctat
     3721 agtaaaacga aacaagaaca gggcaaatcg atcaggacag tcaaatcgat ttctaacaat
     3781 gttttagaag tagaggtgta ctattctagt ttcaatctac tatatttcgt ctgatgggca
     3841 aatcttataa agagattata gagcttttag actgtaatca aacaacgatt tggcgaaatg
     3901 taaaaaaata tgaggagttc ggactcgact ctctctttca agaaacacgt ggtggtcgta
     3961 accatgcata tatgacggtt gagcaagaga aagcctttct tgctcgccat ttgaaggctg
     4021 cagaggcagg agaatttgtt acaattgatg ccttatatca ggcttataaa aaggagttag
     4081 gtcgttccta cacacgtgat gccttctatc aactgttgaa gcaccatggt tggcgaaata
     4141 ttatgccacg tccagaacat cctaggaaag cagacgctca aaccattgtc gcgtctaaaa
     4201 ataaaatctt aattcaagaa gacaagaaag cgctttaaat atagtagacg ttttcgtaag
     4261 gttcgcttga tgtaccaaat agtacgccca tgcaaaagaa tatctatttt gttgtcttgg
     4321 acctgcatac gacggataga gataaaatta tccagctatt caaggattgg acggattata
     4381 gtgccaagtt ggtcgagggg gaattggtta aaaaagatgg acagaatgct ctctttcctc
     4441 cgagcgatac tggtgagaca gttgggctca atcctcatcg tttgacgctg acttttggtg
     4501 tatctgcaag tttcttgaaa aagatgaact tggaaaacaa gcgccctcga ctgttcaggg
     4561 atttacctct atttcctaag gagcaattac gtgaaaaata tactggtgga gatattgtga
     4621 ttcatgcttg tgcagatgat gagcaaattg cctttcacgc tattcgcaat ctcatacgta
     4681 aggggagaaa tgcggtgccc cttcgttgga gtcagtctgg atttgcagct atcggggacc
     4741 gaatggagac tccgcggaac ctctttggtt ttaaggatgg aacagcaaat ccaaccaagg
     4801 agcaagactt tgaccgcgtt atctgggctg atagtaagga ctggatggaa aatggttctt
     4861 atatggcagt tcgtcggatt cagatgtttt tagagacctg ggaccgcact ggtctctaag
     4921 aacaagaaaa tacctttggt cgttacaagg aaagtagtgc ccctttcggt aaaaaaatga
     4981 gtttgatgaa gtgaatttga gttttttgct agatgattcg catgttcgtt tggctaagta
     5041 agtggacaag ccacttttgc gttgttctta ctcttactca gatggcattg atgaaaagac
     5101 tggtcagttt gatacgggtt tgctcttcat ttctttccag aaggatcctg ataactttgt
     5161 taaggttcaa actaatctag gtgctactga taagatgaat gaatacatca ctcacatagg
     5221 tagtggactt tttacttgct ttggtggtgt ggagaaagga gactacattg gtcagaaatt
     5281 attggaaagc taggagctgg ttgcttgttt tagctttgtc atttttaatt ctttccccag
     5341 taggtgccca agaaagtttg agttcttatt tcgtaaaaat cacagatact tctaaagcgg
     5401 tcaaaaatgg caatcagtct gaggcccaga aacttgttca agagatggca tcagacttcg
     5461 aaagagtaga aaataaggat tctgaggttg gtaagattgt taaggaaaag ttagctctat
     5521 ctggagatat tactgaagcc aaactcaccg aaatttcctc agctctatta gcttttgaaa
     5581 aagaacaaaa tcctgttgac ctagatgcgg aaaaggaaaa attggtaaac cgtctaagtc
     5641 ctcgttttga aaccttagag caggccattg cctccaaaga tttggaaaaa gtccgagaag
     5701 cttttaagaa aatgaattcc acttggacca tcaatgaaag tgtggttcgt gacaatagta
     5761 tagctcatta tggacgtgtt gaaacagcta tttccttcct gcctagtagc atggaaaccg
     5821 aacctacaga tgagtctgga acatgaaaac agcagttgat ttcaagaaac aaaaaggaac
     5881 agccgaaact gttctcttat cattatttga gaccgtattt tttgttgaaa cgatccacgc
     5941 gtccatctgc ttgagtgaac ttttgacgtc cagtgtagaa tgggtgtgag tctgatgaaa
     6001 tttccacacg gatcaatggg taagtctcgc cttcgaactc aactgtttcg ttagagcgtt
     6061 ttgttgaacc gctaaggaat tggtaaccag tagttgtgtc catgaagaca actgggcgat
     6121 attctggatg gatatctttt ttcattttgc aatatttcct ttctgccatg gtctctttgc
     6181 gagccataga ttgttaccat actagtctat cagattctga aaagtttggc aagtatttta
     6241 tcagttttta agcaagtttt ttaacttttg gtagatgatt tcgttttcct ctaggctata
     6301 ggaattagca ccacttgcta gagggtggcc tccaccatca tgttccttgg caatttcatt
     6361 gataggatgg attttactgc gtaagcgaac gcggtagtgg ccatcagcct gttccacaaa
     6421 aattccccag agactaacac tatcaatacg cccaggtgca cttacaatgg ctgcagtttc
     6481 agcatcggtt acattgtatt gtttcaagac ttcttgactc aggataacgc gagcagcacc
     6541 attttcatcc acttccagat ggtcgtagat gtagccttgc agtttagcaa ttttgtagct
     6601 catagtgtcc attttgcgag tgagagccgc aaagtcaaag ttatgttctc tcaaataagc
     6661 agccaggcga agagtccgtg cagtggtaga agggtagagg aagcgacctg tatcaccgac
     6721 aattcctgca aagagcaact cagcatcgcg atctgccaag gctagttggg ttgtttgggc
     6781 aaatagggta atcatctcgc tagcgctact tgaactagta tcgacccaag acaggtcacc
     6841 gtatacatca tcatttggat ggtggtcaat cttaatgaga aaatcacctt gactatagcg
     6901 tttatcatcg atacgagcag tattagctgt atcacagacg atgacaagtg cgccttggta
     6961 ggccctatct tcaacaagat ccatctcagc catccaagta agagttggtt catcaaaacc
     7021 gacggctttg atggtttttt ctgggaaatg atgttccagc aaggctttca atcccacctg
     7081 acttcccaag gcatcagggt ctggtttcat atgacgatga atgataatgg tgtcgtattc
     7141 tttaattttt tctaaaattt gttggcaaat ctccataaat aacctcaatt ctttctcatt
     7201 tcattgtagc acaagaattt ttatttttaa aatgaaaaag atgtgatata atggagaaag
     7261 ataaattgag gaggacgata tggcattagc aaaaattgta tttgccagta tgaccggtaa
     7321 taccgaagaa attgcagata ttgtagcaga caaattacgt gacttgggct tggatgttga
     7381 tgttgatgaa tgtacaactg ttgacgcttc agacttcttg gaagcagaca tcgctatcgt
     7441 tgcgacctat acttatggtg atggtgaatt gccagatgag atgatggact tctacgaaga
     7501 cctagcagat ctcaacttga atggcaaaat ctacggagtg gtcggctcag gagatacctt
     7561 ctacgatgaa ttctgtaagg ctgttgatga ctttgaccgt gtctttgtgt caacaggagc
     7621 agaaaaaggt tcagagtgtg ttaaagttga tctttctgcc gaggaagaag atattgaacg
     7681 cttggaacaa ttcgcagaag aattggttgc taaagtagga taagcataaa agtgcgctga
     7741 tgtaatcaat cagtgcattt ttcttatcga gagttgggat tttactagcc taattgatgg
     7801 ctttttgata caataattca aataaaggag gagactgtat ggatttagat attattcgtc
     7861 aagaaatcga tcaaatcgac gaccaaattg tcaaactgtt agaagaacga atgcatttag
     7921 ttgagggggt ggttgcttat aagaaagctt caggtaaacc gattttagat actaagagag
     7981 aagaagttat ttttgaaaag gttgggagtc gtgtagagga caagcgctat caggagacta
     8041 ttgtagcgac tttttcggac atactcaaac gttcgcgtga ttatcaggat caaaatatca
     8101 aatgaaaaaa gaacaatttt atccgctagg aatttttcta gctgctatgt tgggcggact
     8161 tgtccgatat ctagtttcca cctggttacc agccagtcca gactttcctt ggggcactct
     8221 ctttgtcaac tatctgggaa ttttctgctt gatttatctt gtcaagggct atctggtcta
     8281 taaggggact agtaagggct tgattttagc actggggacg ggtttttgcg gaggtttaac
     8341 aactttttcc agcctaatgc ttgatactgt gaagctgctt gatacagggc gttatcttag
     8401 tttgatactg tatttgcttt tgagtatcgg tggaggcctg cttttagctt actatttggg
     8461 gaggaagaaa tggtaatcgt ctatcttgca atcgcctgtg gcttgggagc actcgtacgg
     8521 tatttctttt ctcgctataa tcaagtttct aaattgccac tcggaacgct catagctaat
     8581 cttttaggtt gttttttaat tggagtattc tacaatcatg tagagtctaa ggaagtatat
     8641 gctattctag caacaggatt ttgtggcggt ttaacaactt tttcgacctt gaatgacgaa
     8701 cttcaaagac tgctaagtga taagaaggtc ttttattctt acctgacttt gacttacata
     8761 ggtggtttgg ttgcgatttt tttaggaatt ttgctataaa tttctttact tttttttaga
     8821 aatttggtaa actgtatctt gtgtgtaatg gacgcacaaa aatacagttt atccgctgag
     8881 gaagattcct caagattgac aaagatagga gaataaaatg aatccattaa tccaaagctt
     8941 gactgaaggt caacttcgta cagatatccc atcattccgt cctggtgata ctgttcgtgt
     9001 acacgcgaaa gttgtcgaag gtaaccgcga acgtatccag atttttgaag gtgttgttat
     9061 cgcacgtaaa ggtgctggaa tctcagaaaa ctacacagtt cgtaaaatct ctaacggtgt
     9121 aggtgttgag cgtatcttcc caatccacac tccacgtgtt gaaaaaatcg aagttgttcg
     9181 ttacggtaaa gtacgtcgtg cgaaattgta ctacttgcgt gctcttcaag gtaaagcagc
     9241 tcgtatcaaa gaaatccgtc gttaattcga ctaaaaaact ctgcttttca gcagagtttt
     9301 tatctagctc ccttagttca atggatataa caactccctc ctaaggagta gttgcaggtt
     9361 cgattcctgc agggggcagt aattagatat caaagaagtt tgtcaaaaag tctttgatat
     9421 taaaagaacg cataatatag gggattgtct ccataatatt atgcgtttta ttattgaaaa
     9481 atttgggcaa tcatcagata aaattgagac tatatcgagt atataaatgt ttgtatagtc
     9541 aatttattca aaatcgtcaa gttctaaatt atttaaagga ctataacatt catatttctt
     9601 taagtaattg tttatttctt cagcagtgga acgaggtaaa ttaactctta aatagtcaat
     9661 atcttcctta gataaaaaat gatttgcatt caaaattgag aagcgaaata atgcttcatc
     9721 aaaagcaaaa tcataatcgt catcagataa tgattccatt aatgtttgaa tatgttttag
     9781 tgagtagtca ggtatcgaat cgggataata tactggataa tcagtggctg aaaaattgtt
     9841 ttctaatcct gaaatagtaa ttatcaaaga ttctatgtaa tatattaaag catgtttaat
     9901 attaccttct tgttccaaat gtcttccctg agcctttcgt gtgttagata agcatccaaa
     9961 atctcctgat acagtattcc tatgagcttg tttatttaag agactccatt ttatatcacc
    10021 aaaagttgct ttaaaagaga tattgttttt ttctttacaa taatcttcca tacttatgtc
    10081 tttatcatag tatgctttga tatagtcact atgttcgata ataagatttt gtgcttcttt
    10141 tgttagttta aattcgaacg gaatatctaa tttgtcaacg ttgatattat taattattct
    10201 tgtaattaat tctgcttttt ttccagaagt agctaaatta tgtttagata atatagtttt
    10261 taattctact actttaagat atgataaagt cttattttta gtgaagtatc ctaatttgta
    10321 taattgattg tgtgtagatt cagggtcaat ttgaagagag tatttaaaat atcttgggaa
    10381 attataattt ctccctgttt tttgagtcca atctatgagt atgagttgcc caggagtaag
    10441 gccgcactct aatttgttta ggtaaaaatt gttacaatca gaatttgtgt ctctattatg
    10501 attattttgt tttaaattaa atagtttgct aaaaaaattc attggatttt attgctaatc
    10561 aattcttatt gaaaaatgat acttttacag tacccatgta cggatggcat gggcaacgcc
    10621 agattcatca ttagatttag tgatgtattt ggcgattttt ttgatttctg gatttccatt
    10681 ttccatgaca acagggttgc caacgacttc cagcatggca cggtcatttt cttcgtctcc
    10741 gatagccatg gtttcatctt tggttaatcc tagtttttca gctaagtgag taatagctga
    10801 acccttgtct acattctttt taaggagttc gaggtagaaa ggagcagatt tgttgataga
    10861 gtagtgctcg taaaattcgg ctggtatttt ttcaatcgca gcatcgagaa tttctggttc
    10921 atcgataaac atacatttaa caatttcttt gccagccatt tcttcagggg tacggtagaa
    10981 gataggcatg ctgacgaggg ttgattcgtg tacagtgtat gttccgatat tgcgatttgc
    11041 agtatagata ccgtccttgg taatggcatg catgtggaca ccgagcttgc gactgaggaa
    11101 ttccatatcc agataatcct cataggtcaa ggattcgctg ataatctcat ggccagtagc
    11161 agtttcttgg acaagggcac cattgaaggt caccacatag tcaccttggt ctctcaactg
    11221 caagtcgtct agaagtttgg caacacctgc gatggggcgg ccagttgcaa tcacgacttt
    11281 gacaccagct tctttggcat cttggatggc agaaaagact tcaggagtga tttccttttg
    11341 gctgttgaca agggttccgt cgatatcaac ggcaattagt ttaatactca taaatttcct
    11401 cttctagttt ttatttgggg taaaatgatc gttctcaatc aagtataaaa attgctgggt
    11461 aatgctagca aagatactgt tttgatctaa catttctttc ggaaaataga aacgattatc
    11521 tccgtgacga ctaccagcaa gggattggac gataggagac aggctagaga gttcggccag
    11581 ttctccattc ttttgtaaaa tctcaatctg tgtccgtgga ttttcagatt cgggacgata
    11641 gatatcataa gggaggtcaa agttcttatg aatggcagta tagtagtcgg gatcaaagcc
    11701 aatgtcctca accaattttc tcatgctagc gagttggtct tgatcttctt gtgaaaaggt
    11761 aatggattta aagaccttgc ggttgacaaa gcgttgcgat aaatctgcga gaattttgtc
    11821 aggactggtc atccagagct ggaagtaggt attcatcaca ccatcatcta gagccagata
    11881 gtcagacaag gtcacatttt tttcaaagaa aggcaggagg tgtggggaag ttcgtgcaaa
    11941 gaagtctttg tccttagggt agagttcctt agcgcgcttg agaagattct gtaggagaac
    12001 ttccatagcg cgtgttgctg ggtggaaata gacctgcata tacatctggt agcgactgag
    12061 gacatagtct tcgatggcgt gcatgccatt gcgctgaaag gcgataccat tttcgatagg
    12121 acgaatgact cggaggattc gagtcaggtc aaattcccca taggatgctc ctgtaaaata
    12181 ggagtcacgc aagagatagt ccatgcgatc tgcgtcaatc tgactagaaa tgagttgtac
    12241 gacctgcttg ttaggatagg tatggtctat gacactggca actttctctg gaaaatcggg
    12301 cgctacttgt agcaagactt ggtgaatctc tgtctcagga ctttgaataa tctcctgagt
    12361 aatagcttca tggtctgtat caaagagatg ttcaaaagta tgggagtagg cgccatgccc
    12421 aaggtcatgt aggagagcag cgatcatggt caagagagac tcggcaggat tccattcctc
    12481 aggatatttt tcttcgaaaa tctctgtgat gcgtcgtgca atttcataga ctcctagaca
    12541 gtgagagaag cgactgtgtt ctccaccgtg gaaggtataa ctggaagttc ccagttgttt
    12601 gatccggcgc aaacgctgaa attcttttgt attaatcaag tcatagatga tttgattaat
    12661 gacatggatg tagttgtgaa ctgggtcacg gaatactttt tcgttcatat gaccattata
    12721 gcaaaatcct gctctttttg gtaaaatagt aggacaagag acaagaaaga gggcctgatg
    12781 tgaagattcg gatgcgaaat acaattcagt ttgatgagca gttggaagtg attgaccagc
    12841 tttatgatgt ggaagtgcat gaaaaaggag attatagcta cctgcttttc tataatgagg
    12901 aaaaggaaaa agtagtgatt aaatttcatg gtcaagaact tgtgatgagc cgattttcta
    12961 atcccaagac cattatgcgc tttctaaaga atagcgatag tttagcctat attcctacac
    13021 ctatgggcat gcaggagttt atcatccaaa cgagccatta tcaagttgat aggcaaaaga
    13081 ttgaactaga ttatcaacta caaaatcaag agggacatcc ttttgccagc tatcaattgg
    13141 aaattacttg gggctaggct catgtctttt tcaaatttag ctatctatct tcttggatcg
    13201 gtttcctagt gtggtagatt aggctaattt ttggtataat aaaagttatg gaaatcgaaa
    13261 aaaccaatcg tatgaatgcg ctctttgaat tttatgcggc gcttttgaca gataagcaaa
    13321 tgaattatat cgagctctac tacgctgatg attacagcct tgctgaaatt gccgaggagt
    13381 tcggtgtcag tcgtcaggct gtctatgaca atatcaagcg aacagaaaag attctggaag
    13441 attatgagat gaaattgcac atgtactcgg actatattgt ccgcagtcag atttttgatc
    13501 agattttgga gcgctatccc aaggataact ttctgcagga gcagatagaa attttaacaa
    13561 gcattgataa tagagaataa gaggaagaaa aatggcattt gaaagtttaa cagaacgttt
    13621 gcagaacgtc tttaaaaatc tacgtaaaaa aggaaaaatc tctgaatctg atgtccaaga
    13681 ggcaaccaaa gaaattcgct tggccttgct cgaggccgac gttgccttgc ctgttgtaaa
    13741 ggactttatc aagaaagttc gtgagcgtgc agtcgggcat gaggtcattg atacacttaa
    13801 tcctgcgcaa cagattatta aaatcgttga tgaggaactg acagccgttt taggttctga
    13861 tacggcagaa attatcaagt cacctaagat tccaaccatc atcatgatgg ttggtttaca
    13921 aggggctggt aaaacaacct ttgctggtaa attggccaac aaactcaaga aagaagaaaa
    13981 tgctcgtcct ttgatgattg cggcggatat ttatcgtcca gctgccattg accagcttaa
    14041 gaccttggga caacagattg atgtgcctgt ctttgcactt ggaacagaag taccagctgt
    14101 tgagattgta cgtcaaggtt tggagcaagc ccaaactaat cataacgact atgtcttgat
    14161 tgatactgcg ggtcgtttgc agattgatga gctcctcatg aatgagcttc gtgatgtgaa
    14221 agcattggct caaccaaatg aaatcttgct tgtcgttgat gctatgattg gtcaggaagc
    14281 agccaatgtt gcgcgtgagt ttaatgctca gttggaagtg actggggtca tccttaccaa
    14341 gattgatggc gatactcgtg gtggtgctgc tctgtctgtt cgtcacatta ctggaaaacc
    14401 aatcaagttc actggtacag gtgaaaagat tacggacatt gaaaccttcc acccagaccg
    14461 catgtctagc cgtatccttg gtatggggga tatgctcact ttgattgaga aagcttctca
    14521 ggaatacgat gaacaaaaag cccttgaaat ggctgagaag atgcgcgaaa acacctttga
    14581 ttttaatgat ttcatcgatc aattagatca ggtgcaaaat atggggccga tggaagactt
    14641 gctcaagatg attccaggta tggccaacaa tccagccctt caaaacatga aggtggatga
    14701 acgccagatt gctcgtaaac gtgccattgt gtcttcgatg acacctgaag agcgtgaaaa
    14761 cccaaatttg ttaaatccaa gccgtcgccg tcgtattgct gctggttctg gaaatacatt
    14821 cgtcgaagtc aataaattca tcaaggactt taaccaggct aaacagctca tgcagggtgt
    14881 tatgtctggg gatatgaata aaatgatgaa gcaaatgggg attaatccaa ataaccttcc
    14941 taaaaatatg ccaaatatgg gaggaatgga tatgtctgcc cttgaaggaa tgatgggaca
    15001 aggcggtatg cctgacttat cagctctcgg aggagcagga atgccagata tgagccagat
    15061 gtttggtggc ggtttgaaag gtaaaattgg tgaatttgcc atgaaacagt ccatgaaacg
    15121 tatggctaac aaaatgaaga aagcgaagaa gaaacgcaag taagacaaga gattgatgca
    15181 aatctcattt gatgagaaaa taaagtaaaa atttctatga taaaacgtat agtatcaagg
    15241 ttttagaata tctgatatta tacgtttttt gattttaata attttgttaa gacactttta
    15301 ttatggtatg cgaaaaatcc actcagctgt ctgagtggat taggtgtatt tagactctta
    15361 gtctttattt tcgtatggca agatcaagtt caagatgatt cctgtcatgg ctgaaagggc
    15421 agtacctgaa agtgtaactg gaccaagttt aaggatagct cctccaagtc caagaaccaa
    15481 catagcactt gcgatgatga ggtttcgcat ttgagcgaaa tcaacacgtt ctttaatcaa
    15541 gactttcaaa ccattgctgg cgataacccc atagagaagg attgacatac caccaagtac
    15601 agcgtttgga atagttgaaa tcaaggcagt gaatttacca aggaagctga gggcaatcgc
    15661 gatgaaggca gcgttacgga taactgagac agaagcgata cgagtcatac cgataacccc
    15721 tgtattttct ccgtaagttg tattggctgg tccaccaagg aaggcagaaa cagaagttgc
    15781 gataccgtca ccaagaagag tacggtgaag acctggttct tttaagaatt gacgaccaca
    15841 gatttgaccc aaaacagtat ggtctccgat atgttcagaa attgttacga tagcgattgg
    15901 caagatagcg atggcttctg gaccaaagta aagattgtac tctttaaagg caccacctgt
    15961 gctaaatggc aagtagaaac caggaatttc gaaccagttg gctttaagaa ctggtgtaaa
    16021 gtcaaccaag ccaagagtta gtgcgaaaag gtaaccaccg ataatggcaa agaggaatgg
    16081 aatgattcgt aggaagcctt ttccttttgt attgataaag gcagcaatta ggaaagtaac
    16141 aacggctacc agagcatttt tccaatttcc gtctgctaca agacctgcat tggtaacagc
    16201 tgaacctgca agtccaagac cgataacgat gatcatagga ccgataatga ttggtggcaa
    16261 gagtttatca atccattttg ttcctacaaa tcggatgctg gtagcaacaa ggacatagac
    16321 caaaccagtc aagataaccc ctgtttgggc agcagataca tcccccccca tttctttcat
    16381 agccagtgac atagctgtga taaaggcaaa tgaagaacct agataaactg gaactttaaa
    16441 accagtagca atcatgtaga tgagtgttcc aacacctgaa gcaaaaaggg caacagatac
    16501 aggcattccc aaaatcaatg gtaccaagat ggtcgcacca aacatggcga aaacgtgttg
    16561 gaagctaagg agaattcctt ttccatccga aggacgttgg tcaacgtcta gtaacaaatc
    16621 aacagttgat tcttgtttca tataaacctc acttttgggc atcagaaaag agcccattat
    16681 tttacagcaa taggccctca gagtaagact tctctaaaat ctagacttta aagagtttca
    16741 aatatttttg cgtcttcgtc acctcacggg atgacattaa aaacctttgc ttaggatagt
    16801 atagcagaaa aaaatgattt tgtaaatcat tttttcccga gcctagaaat aaaagagcga
    16861 ggctgatttt gtaaacattt gtttactaaa aaatttaaag tgggcgttta tttggcatac
    16921 cagccttacg tggatattta tttggtgttt cttttttctt ttctaccact gtgatatagc
    16981 gcggatctct attcggtagg gcgtagctga gattgtcttc gaccttacta aaaaggagat
    17041 tgagggcatt cttagcttct aataattcct caggcgcatt gctggccttg agtgccaata
    17101 gtttgccacc aaccttaagg tagggaatag tcaattcaga taggacctgc atacgggcaa
    17161 ccgcacgagc tgttacaaaa tcatattgag cacggaagtt cttgtcttgg gcaaaatctt
    17221 cggcacgtcc gtggtagaaa tgaactccgt tcaaatccag ttcttgagcc aagagttgta
    17281 ggaagttgat gcgcttattg agtgaatcaa taatggtcac atctaactcc ggatagagaa
    17341 ttttcattgg tagactagga aatcctgccc cagccccgat atcaagaagt ttgatagttt
    17401 cattgggaat caaaccttga agaatgggtg caatcgaatc gtaaaaatgt ttgagataaa
    17461 cttcttcctt gtccgtaatc gccgtcaaat taatcttctc attccactcg accaagagct
    17521 caaaataacg ttcaaattgt tctttttgct ggttcgaaag tggaagattc tgctcggcaa
    17581 gcaagttgta aaatgtttct ggtttcatag ttatttcctt ctttagtatc atcttatttt
    17641 accacaatca tagaaaattt gatatactgg tactaatcta aaagcagaaa ggacttatat
    17701 tatgacttgg attattcttg gagttatcgc tcttattgtt atttttgtga ttgttagcta
    17761 taacggtttg gttaaaaatc gtatgcaaac caaggaggct tggagtcaga ttgatgttca
    17821 gttgaaacgt cgaaatgacc tcttgccgaa cttgattgag actgtaaaag gttatgccaa
    17881 atatgaaggt tctacccttg aaaaggtggc agaactacgt aaccaagtgg cggcagcgac
    17941 ttcaccagca gaagctatga aagccagtga tgccctcact cgtcaggttt caggtatttt
    18001 tgcagttgca gaaagctatc cagatttgaa agctagtgct aactttgtta aattgcaaga
    18061 ggagttgaca aacacagaaa ataaaatttc ttactctcgt caactctata acagtgttgt
    18121 cagcaactac aatgtaaaat tagaaacttt cccgagcaat attatcgctg gaatgtttgg
    18181 atttaaagcg gcagatttcc ttcaaacacc tgaagaggaa aagtcggttc ctaaagttga
    18241 ttttagcggt ttaggtgact aagatgttgt ttgatcaaat tgcaagcaat aaacgaaaaa
    18301 cctggatttt gttgctggta tttttcctac tcttagctct tgttggttat gcggttggtt
    18361 atctctttat aagatctgga cttggtggtt tggttatcgc actgattatc ggctttatct
    18421 acgctttgtc tatgattttt caatcgacag agattgtcat gtccatgaat ggagcgcgtg
    18481 aggtggatga gcaaacggca ccagacctct accatgtagt ggaagatatg gctctggtcg
    18541 ctcagattcc tatgccccgt gttttcatca ttgatgatcc agccttaaat gcctttgcga
    18601 caggttctaa tcctcaaaat gcggctgttg ctgcgacttc aggtctacta gctatcatga
    18661 atcgtgaaga actagaagct gttatgggac atgaagtcag tcatattcgt aattatgata
    18721 tccgtatttc gactattgca gttgcccttg ctagtgctat caccatgctt tctggtatgg
    18781 caggtcgtat gatgtggtgg ggtggagcag gtcgcagacg aagtgatgat gaccgagatg
    18841 gaaatggtct tgaaatcatt atgctagtgg tttccctact agctattgta ctggcacctc
    18901 tcgctgcaac cttggttcag ctcgctattt ctcgtcagag ggaatttctg gcagatgcat
    18961 ctagtgttga gctgactcgc aatccccagg gaatgattaa tgccctagat aagttggaca
    19021 atagcaaacc gatgagtcgc cacgtcgatg atgctagcag tgctctttat atcaatgatc
    19081 ccaagaaagg tggggggttc caaaaactct tttataccca cccacctatc tcagaacgga
    19141 ttgaacgttt aaaacagatg taaaagaatc cagaggtcgt ctctggattt ttgctatgtt
    19201 gcaaatttat aaatcttcta aattaactaa ctccaaaccg tgttctgtca tgcgatagat
    19261 gatcgagcag acttctttta agaaacgacg gtcatgcgaa acagtgatga gaccgcctgg
    19321 ataggttgca aagagttttc tgatttgggg ttgagaagtg ggagaaaagt ttcgtgtggg
    19381 ttcatccagc aggagaaagt ttggtttgcg caggactaga tccaaaagca ggagttttcc
    19441 ctgttgtccg ccagataagg agcgaatttg atgctgcatt tctggataac tgaaattgag
    19501 actggctagg tgagagtgga ttttctgaag ttcctctttt tccccagttt tgctgatata
    19561 agctattggt gataaatcca attgtagttt tttgtggtaa tcttgtggca taaaaccaag
    19621 ggaaatctct cttttatcat tcagaagttg ctttaatttg gctaacagag ttgatttccc
    19681 aacaccattt ggcccgataa taccgatttt ttcttgccca cggacagtta gttgtagttt
    19741 ttgaaccaaa actcggtcgt caatggacaa attttctttt tccagttgga ctaagacttt
    19801 agaagctggt aatggttgga tgtctgaaaa gaaaagttgg atttgttcct cttcaagtgg
    19861 tttttgagtc atggactgag ctgccttttc gtagcgtttt tcttgtgaga ggacagtttt
    19921 catcttttta gccaataggc gaccggcagt actatctttg gtagctcgaa gcgcagtttc
    19981 tacattttgc ttaactctcc gatgtttttc catggtttta tcgtaggctc tttggttgtt
    20041 agcagcttgc tgactttgtt tggcaaaatt agcctttctc tgctcactat agctatcata
    20101 gtctaaatgc tctactagcg tttccgcttc tttacggtgt ttgaccagtc gcaagtgaac
    20161 aatagtgtct gccgtttcag aaagaaagtc ttcatcatgg gaaatgaaaa taacggtttg
    20221 cctggtcttt tgaatctggc cttttagcca atcaactgtc tcaaggtcta ggtcatttga
    20281 aggttcatct aaaaatagaa tctcaaaggg tttggctaac tcatggataa gctgaatttt
    20341 caaagcttct ccccctgata gattgccaat ctcttggtca cttgcgaaac gattgctatc
    20401 aaaatgcaat tcctccgcca aacgatagag gatactgtag tctaaatcaa tagaatctaa
    20461 aaagaagtag tcgtgtaaag ttttcttttt cagctcctcg ggaagttttt gaggaatgta
    20521 ggccagtgac tgatagtcag attggatgtt tcccttgata gtgaaatcag acaaagcttc
    20581 ccccattaaa gttttaagta aggttgattt accatttcct tcttcgccaa taatagctac
    20641 cttttccccg tcttgtatgg tcatgcttag gtcagagaca aggtctcgta aatctttgtt
    20701 ttgtgtgatg gtcaggtgat tgatttttat catactattg ccctttctag aatgttcata
    20761 gtgcataaca aaaagctcta ctttacctag tagagcccaa agtctatgtc aaaaaaactc
    20821 tattaacatg ccagaaaaag ggcataaaag agcacacaaa aagagacaaa aacaagatct
    20881 actaaataaa ggttctttat ttgatagact tagttgttca tgtctccctt acctcctagt
    20941 attagtatct ttatactata cttttaagga aattttgtca acagaaaact ggaaattcta
    21001 tgctctaaaa tccaaaaaca ggtctataga gacttagtac gtgtttgaca tgctcgtaat
    21061 ggattttatc atagtttcgc caagcagtgc gttcttgatt gtttagtttt aggctaccca
    21121 gtccaatcat aggactggtg ggttggtaaa atttctcaag atcaattaag atactgttgt
    21181 tcaacttttc cgttttttga gttcttgcat agtagtgttt agcagctctt gtagtcgaat
    21241 atcatctgcc gtaccctgtt tacagttttg gtagctttta tttaacttgg ataggagttg
    21301 aatgagtttc ttgtcttccg tgtgagcatc ctccttgatc tgatgtactc tttccctata
    21361 gtatagcact aaaaaataaa actgtcatag tgaatatgtt aaaatttcga attttaatta
    21421 caaagtttgg tgtgctgatt tgtagccttt tcatggtata atcaagagag taaatcttta
    21481 tggaggaagt atgaaattaa atattcaaga aattcgtaag cagtctgaag gtttgaactt
    21541 tgaacaaacg ttagatttag ttgatgacct gcgtgcacgt aatcaagaaa ttttagatgt
    21601 aaaagatatc cttgcagttg ggaaagtaca atatgaagac cgtatgtatt tcttagatta
    21661 tcaactatct tataccattg ttcttgcttc gagtcgcagt atggagccag ttgagttagt
    21721 tgaatcttat ccagtcacgg aagttttcat ggaaggcgca actaaccagc tagatcaaga
    21781 agttttagat gatgacttgg tcttgcccat cgaaaatggg gagcttgacc ttgctgagag
    21841 tgtatcagac aatatcctgc taaacattcc tatcaaggtc ttgacggctg aagaagaagc
    21901 tggtcaagga tttgtctcag gaaatgactg gcaaatcatg acagaggaag aataccaagc
    21961 tcaacaagca gtaaagaaag aagaaaacag tccttttgct ggcttacaag gactatttga
    22021 cggagatgaa taatggtctt gtcaaaaaaa cgagcacgaa aggtgctaga agaaatcatt
    22081 gccctcttcc cagatgccaa gcctagtctt gattttacca atcattttga actcctggtt
    22141 gcggtcatgt tatcagccca gacgacagat gcagcggtaa ataaggccac accaggtctc
    22201 tttgttgcct ttccaacacc ccaagctatg tctgtagcga cagagagtga gattgcttca
    22261 catatttctc gcttgggatt gtatcggaat aaagctaaat tccttaaaaa atgtgcccaa
    22321 cagttactag acgattttga tggtcaagtc cctcagacac gtgaagaatt ggagagtttg
    22381 gcaggtgttg gtcgcaagac agccaatgtt gtcatgagtg taggatttgg gattccagcc
    22441 tttgcagtgg atactcatgt ggagcgtatt tgcaaacacc acgatattgt caaaaaatca
    22501 gcgacgccac ttgaggtgga aaagcgggtc atggatatct tgccgcctga gcagtggtta
    22561 gctgcccatc aggccatgat ttattttgga agagccattt gccatccaaa aaatccagag
    22621 tgtgaccagt acccacaatt atatgatttt agcaatttgt aagatgctac attgaaactt
    22681 tttgcttgat tttaagcatg ctttgtgcta tagtaaatga taactaaata ttcctttaaa
    22741 cctgtcccgt gaggcaggca aggagcgcga taaagtagaa gggtgaagtc tatactgtgt
    22801 gcagtagggc tcgcttggct ataaatttca agtctccttg tttaaggaga cttttctttt
    22861 tggaggtttg tcatgaaaac aaaagaagtt gtagacgaat tgaccgtcaa acgagcgatt
    22921 acgcgtatta cttatgagat tatcgaacgc aacaaagatt tgaataagat tgtcttggct
    22981 ggtattaaaa ctcgtggtgt ctttattgcc caccgaatcc aagaacgttt gaagcagtta
    23041 gaaaatcttt cagttcctgt tgtggaattg gatactaaac ctttccgtga tgatgttaaa
    23101 agtggagaag atacttcttt ggtttctgtc gatgtgacag accgcgaagt tatcttggtg
    23161 gatgatgtgc tctatacagg tcgtaccatc cgtgctgcta ttgataatat tgtcggtcat
    23221 ggtcgtcctg cgcgtgtgag tttagcagtt ctagtcgatc gtggacatag agaattgcca
    23281 atccgtccag attacgttgg aaaaaatatc ccaaccagtc gttctgaaga aatcatcgta
    23341 gagatgacag aacttgatga ccaagacaga gttctgatta ctgaagaagc ttagaaagtt
    23401 aaaggagtag ccatgtcaga aaatcaacaa gcattgaacc atgtggtgtc catggaagac
    23461 ctcactgtcg atcaagtaat gaaattgatc aagcgaggaa ttgagtttaa aaatggagcc
    23521 cagcttccct atgaagacca tccgattgtt tccaatctct tctttgagga ttctacacgg
    23581 acacataagt cctttgaagt cgcagagatt aaacttggat tggaacgact tgactttgat
    23641 gtgaagacta gttcggttaa taagggtgag acactttatg acaccatttt gactctgtct
    23701 gctttaggag tggatgtctg tgtgattcgc catccagagg tcgactacta tagagaattg
    23761 attgctagtc caacgattac gacttccatc atcaatggtg gagatggttc gggccaacac
    23821 cctagccaga gcttgcttga tttgatgacc atttatgagg aatttggcca ctttgagggt
    23881 cttaaagttg ctattgcagg tgacttggac cactcacgcg ttgccaaatc caatatgcag
    23941 attttgaaac gcttgggatc tgaactcttt ttcgctggac ctgaggaatg gagaagtcaa
    24001 gagtttgcag actatggaca gtttgtaacc attgatgaaa tcattgatca ggttgatgtc
    24061 atgatgtttc tccgtgtgca acacgaacgc catgatagtg gagctgtatt ttcaaaagaa
    24121 gactaccatg cccaacatgg cttgactcaa gaacgttacg atcgtttgaa agaaacagca
    24181 atcctcatgc acccagctcc aatcaatcgt gatgtagaaa tagcagacca cttggttgaa
    24241 gcaccaaaat cacggattgt ccaacaaatg accaatggtg tctttgttcg aatggcaatc
    24301 ttagaatccg tactagcgag tagaaacgcc aactaaaaca caagacgtta aaagacgcca
    24361 gtgagcgtcc acgagaggtg aaaatatgac aaaaagaatt ctagtattag aagatggcac
    24421 agtttttgaa ggcaaggcct tcggagcaga tattgatgta acaggcgaaa tcgtctttaa
    24481 tacagggatg accggctacc aagaatccat tacagaccag tcttataatg gacaaatctt
    24541 gacctttact tatcctttgg tcggaaacta tggaattaac cgtgatgatt acgaatctat
    24601 tattccaact tgtaagggag ttgttgtttt cgaaaaagcg cgtagagcaa gcaactggcg
    24661 caaccaaatg accttggatg aatttttgaa agccaagaaa attcctggta tttcagggat
    24721 tgatacgcgt gcacttacca agattattcg taagcatggt actatgcgag caaccttgac
    24781 tcatgttgga gatagtatgg accatgtgac tgaccagctc caagcaacag tattgccgac
    24841 agataatatt aagcaggttt ctactaaaac ttcctatcca gctccaggag ttggtttgag
    24901 cgtggtgtta gtagactttg gtctcaagca ctcaatccta cgtgaacttt ctaagcgcaa
    24961 ctgtaatgtg acggttgttc cttattcgac aacggctgaa gaaattctcc atctcaatcc
    25021 tgacggagtg atgttgtcaa acggtccagg taacccagaa gatgttccac aggcactgga
    25081 tatgattcgc ggtgtacaag gaaaaattcc aatctttggt atctgtatgg gacatcaact
    25141 ctttgctatg gcaaacgggg ctaagaccta taagatgaag tttggccacc gtggattcaa
    25201 ccatgcggta cgtgaaatcg caacaggacg agtagacttc accagccaga accatggtta
    25261 tgcagtcagc cgcgaggatt tgccagagca cttgattatt acccacgaag aaatcaatga
    25321 caagtcagtg gaaggtgtgc gccacagata ccaacctgct ttctctgttc aataccaccc
    25381 agatgcagct cctgggccac acgacgctag ctacctattt gacgagttta tcgagatgat
    25441 ggaagttttt aaacaatcaa actaagaacg agtaaaagct cgtcggagaa tttatgtaac
    25501 tgaacacgga cggaaagctc agaatttaga gaaaccaact tggattgtca atccttcctt
    25561 gatttcttaa aattcaatcg ctttctattc gtcctttgta tcttatttaa tgtcgccctg
    25621 agaggcgacg aatagaaagg agaagggtgc tccgtatttg ctgaactgaa tacgggctac
    25681 ggacggtgct aaaaagatag ttattcctag aactgacagt tcttcgtcat aactcctatt
    25741 ttagctttgt ccgcttgacg cccttaatat cttatatatg cctaaacgta ctgatattca
    25801 aaaaattatg gtgattggtt ctggtccgat tattattggt caggctgctg agtttgacta
    25861 tgctgggacc caggcttgct tgtcgttgaa agaggaaggt tatgaggttg ttttggttaa
    25921 ctcaaatcct gcaaccatca tgacggacaa ggaaattgct gacaaggttt acattgaacc
    25981 gattacactt gagtttgtga cacgtattct tcgtaaggaa cgtccagatg ccttgctacc
    26041 aacactcggt ggtcagacag gtctcaacat ggccatggaa ttgtctaaaa atggtatctt
    26101 agatgagctt agcgttgaac ttctgggtac taaattgtct gccattgacc aagcggagga
    26161 ccgtgacctc tttaaacaat tgatggaaga gcttgagcaa cccattccag aatctgaaat
    26221 tgttaacaca gtagaagaag cagttgcctt tgcagcgaca attggctacc cagtcatcgt
    26281 tcgtccagcc tttacccttg gtggtactgg tggtggtatg tgtgccaacg agaaagaatt
    26341 gcgtgaaatc actgaaaatg gtttgaaatt gtcacctgtt acccaatgtt tgattgagcg
    26401 ttcgattgct ggtttcaagg aaattgaata cgaagtgatg cgtgactcag ctgacaatgc
    26461 cttggttgtt tgtaacatgg aaaactttga cccagttggg attcacacgg gggattccat
    26521 tgtatttgcc cctgcgcaaa ccatgtcaga ctatgaaaac caaatgcttc gtgatgcgag
    26581 cttgagcatt attcgtgccc tcaagattga aggtggatgt aatgttcagc tagctcttga
    26641 tcctaacagc ttcaagtatt atgttatcga agtaaaccct cgtgtatcac gttcgtcagc
    26701 ccttgcttct aaagcgacag gatatccgat tgctaagttg gctgccaaga ttgcagtagg
    26761 tttgaccttg gatgaggtta taaacccagt tacaggttca acctatgcca tgtttgaacc
    26821 agcccttgac tacgtagttg ctaagattcc acgtttccca tttgacaagt ttgaaaaggg
    26881 tgaacgccgt ctcggtacac aaatgaaggc gactggagaa gtcatggcaa tcggtcgtaa
    26941 catcgaggaa tctcttctca aggcctgccg ctcccttgaa attggggtgc accacaatga
    27001 aatacctgaa cttgcagcag tttctgatga tgccttgatt gaaaaggttg tcaaagccca
    27061 agatgaccgt ctcttctacg tatcagaagc aattcgtcgt ggctacacac ctgaagaaat
    27121 tgcagagctt acaaaaattg atatcttcta tcttgataaa ctcttgcata tctttgaaat
    27181 tgagcaagaa ttgggtgctc atccacaaga tctagaagtt ttgaaaacag ccaaacttaa
    27241 tggtttttca gaccgtaaga ttgctgaact ctggggaacg actgatgata aagttcgcca
    27301 acttcgcttg gaaaacaaga ttgttccagt ttataagatg gtagacactt gtgcggcaga
    27361 gttcgactcc gaaacgccat atttctattc aacctatggt tgggaaaatg aatctatcag
    27421 atctgataaa gaatctgtac ttgtcctagg ttcaggtcca atccgtatcg gtcaaggggt
    27481 tgagtttgac tacgcaaccg ttcactctgt taaggctatc caggcagctg gttatgaagc
    27541 tatcatcatg aactcaaacc cagagaccgt ttcaacagac ttctctgtat cagataagct
    27601 ttactttgag ccattgacat tcgaagatgt tatgaacgtc attgacttgg aacaaccaaa
    27661 gggagttatc gttcagttcg gtggtcaaac agccatcaac cttgcggagc cattggcaaa
    27721 agcaggtgtg accatccttg gtacacaggt tgctgaccta gaccgtgccg aagaccgtga
    27781 cctcttcgag caagctctca aagaattgga tattccacag ccaccaggac aaacggctac
    27841 caatgaagaa gaagcagctc ttgcagctcg taagattggc ttcccagttc ttgtccgccc
    27901 atcttatgta cttggtggac gtgccatgga aatcgttgaa aacgaagaag accttcgttc
    27961 ttacatgcga actgctgtta aggctagtcc agatcaccca gttcttgtcg actcttatat
    28021 cgttgggcaa gagtgcgaag ttgatgccat ttcagatggt aaagatgtgc tcattcctgg
    28081 tatcatggag catatcgaac gtgctggtgt ccactcaggt gactcaatgg ctgtttaccc
    28141 accacaaacc ttgtcgcaaa aggttcagga gaccatcgca gactacacca aacgcttagc
    28201 aatcggtctt cactgccttg gaatgatgaa catccagttt gttatcaagg atgaaaaagt
    28261 ctacgttatt gaggtcaatc cacgtgccag ccgtactgtt ccattcctat ctaaggtaac
    28321 caatattcct atggctcaag tagcgaccaa gctcattctt ggtcaaagtt tatcagaact
    28381 tggctaccaa aatggacttt accctgaaag cacccgtgtt catatcaagg cacctgtctt
    28441 ctcctttacc aaactagcta aggtagacag cttgctcggt cctgaaatga agtcaacagg
    28501 tgaagttatg ggttctgatg ctactttgga aaaagctctc tataaagcct ttgaagcttc
    28561 ttatctacac ttgccaactt ttggtaatgt cgtctttacc atcgctgatg atgccaaaga
    28621 agaagccttg aacttggctc gtcgtttcca aaacattggt tatggaatcc ttgcgacaga
    28681 agggacagca gccttctttg ctagtcatgg cttgcaagcc caacctgttg gtaagattgg
    28741 tgatgacgat aaggatatcc caagttttgt acgcaaagga agaattcaag ctatcattaa
    28801 cacagtagga acaaaacgaa ctgctgacga agatggtgag caaattcgtc gttcagccat
    28861 tgaacacggg gtgcccctct tcacagcgct agatacagct aatgccatgc ttaaggtact
    28921 tgaaagtcgt agctttgtta cagaagcgat ttaaatagaa aaataagata tagcagactg
    28981 aatttagaac agtacacagg aatactaaaa tatttctata aattaatttg aattttctaa
    29041 ttgatttgtt cgcatcttat ttcaatctac tatagaaaaa agtctttaaa attataaaac
    29101 gcatcatatc aaggtttttc aaaaaccttg atatgatgcg ttttattgtg ggaatatgta
    29161 tttcattttc tactaaaatt atgtttttga ataacctcta tcttagtagt ttgtataatc
    29221 cccctcaatc agtttttgcg ataagcttta atgctatgac tataccactc ttgcatttct
    29281 tttgatggtg gtgtcatata atcgccatac atctgggtta aaaattggtc atattttttg
    29341 ggaacaggca acatacggcc ctcaaactca gttaaaatca gttctttaaa ggtatcaact
    29401 gggaagattt ctttcatccc ttccttaccg atcccaactc ctccttcata ttgaggaatg
    29461 ttggttacag catttttgac tagttgatca attttcttgt aaaagtagcg aggattgaca
    29521 aatcggagag cgtaccagct acataatcta agaaaatctt ttagtttgct atcaccgtga
    29581 actgctcgtg attttttgat ataagctagt tgacgaagag ccacatactt atagctcttg
    29641 tcgacaatgc tcaagtctgt aaatcgatca attgggaaga catcgatgaa aaggctggta
    29701 tcatgacgct tgtacttaac atggtcttct ataacagtag aagtgtccaa aatcgatgcg
    29761 aaattatgga agtaccaaga agatgtatcg taggaaagaa ccttgtagcg agggtgattt
    29821 tcttcttcaa taatcttcag taaacgctca taatcctcac gataaaggga aatatcaata
    29881 tcatcatccc aaggaatcat acctttgtgg cggatggctc caagcatggt tccataactg
    29941 agaaaataag gaatatcatg tttcttacaa gtctcatcaa tatagtccag cagggctagt
    30001 tgaatttctt taatttcttt tttttctaaa tattgcatcc taatcctcca atttataagc
    30061 gtgaaattca tgactgtaga agcgtttttc ttctggtggt agggtcatat aatctccata
    30121 aaattgtgtc aaaatagtat caaatttttc aggtgcagga aggcttaaat tctcaaaggg
    30181 taaatcgatt gttttatcaa aggtaccact tgggaagact tccttttcct taaattttga
    30241 agggataaaa gccatatact gcccattttc acgactatat ttttgaattt ctttctcgat
    30301 tttatttgca aaataacgag gagaaactgg tcgaaggagc aaccaaaagg ctgttcgtat
    30361 ccaatctttt aaaaggctat ccttatagac aatattttta tgtttactga aagacagcag
    30421 tttgaagctt tccagtttat aacaagtatc aatgacctta ggatcatcaa agcgatctat
    30481 agggaaaata tcgataaaga taccagactc ataggttttt gtatttcgag tatcaataat
    30541 tttagtcgta ctgtcggtta tcttgataaa gttgttaaag tagttcttat cagtttctaa
    30601 ggataggagc ttatacttgc ttttttcctt ttgaaaaatg ttaataaatc gttggtagtc
    30661 ttctctaggc atggataaat caatatcgtc gtcccaaggg ataaagccct catgtcgaac
    30721 cgccccaatc agagtaccgt agttaataat atagttgata ttgtgctttt tacagagagt
    30781 atcaatataa tccaaaattt ctaattcaat ttgtttggca tcttcaatgg ttagttgttt
    30841 cattttaaac tcctatgatt ttttgaattt attttttaag gctaggacat ggtttaaaaa
    30901 ttcatagaaa atgctatctt ttgtgaagac aagtagacta atataagaga tagctgatag
    30961 caagacaatc aaaccagtat taattaaaaa tggcaaatta atgaccatat ccacaggata
    31021 cacgaaatta atcaggaaat aaattgctac aaaggaaagt gaaaagagag agtatcgaac
    31081 agtatagcta aagatatgtc ccaagtggat gagttgtttt ctatggatga aaataatata
    31141 gaaaacaagt agagaagtct ctgataacat agttgtcagt aagtagtatt caggaaccac
    31201 gatatggttg aaaaagagga gactattcaa gcccaaattg agtagcccag caaagactgt
    31261 atagactgtg atacgttttt catagccatt ggtaaagaga atttgggaac caagaatggt
    31321 atctaaggcc aggataatcg tacgaaaagc gaagagagag gtcaagatgc cgcctccgat
    31381 atatttttca ctaccgtaaa gtaggatggc atttggtcct aaaaccatga gtccaaaact
    31441 cagtggaatg ataaagaagt taaagattcg actacctcta ttaaccagag aaacataggc
    31501 ttctttgtct cctttcccca gatagtaact gagacgaggc acactcactc caattgcacc
    31561 tgttacaacc ccagctataa cggtcacaat tcgctgagct atggtatagt aactaacgtt
    31621 gacatcaatc cctgttttaa cgaggaagag gcgatctaaa aaagtgaaga gcatattggc
    31681 attggcaaag actaacatgg ctgtcagagg gagaaagagt ggtttaaaat cacttaggtg
    31741 aatcttaaca agtttgatgt ctcttttaat ccaaaaataa ctaatcaggt agttaatcag
    31801 cgtcgataaa ctcatcacaa gtgtatagac aacaatatcg tgttcatttt taacaaataa
    31861 gaaaatagag accagcatca ggatacggat gaaggcagtt ttgtaaaaga gaaaactgta
    31921 attttccaga gcttcattga cccattcgat tgaaaaaatc tgggcaatga gttgaatccc
    31981 cataacaagg tagacctttt tgacgattgg attatcaata aagaagagag gataggctag
    32041 gatatagaca gcagtggtca aaatcgtaca agcgatgcac aaataaaaaa gactagaaaa
    32101 ggttctgtta agatcttttt tgttatcctt gacattactg atagccctta aaccgtagtt
    32161 atagacacca taagttgcaa agggcaagaa aaatgacaaa atagtgtcga ctgagttgaa
    32221 gtaaccatag tcagttcggt ccaagacacg cgcgacatag gttccagtta ggatgggaaa
    32281 aataatattc aagacacgaa ttcccatgta agatagagca tttaatttta tacttttcat
    32341 tcaatttacc tcgtttttca ttatatcata aagttagcta ataagaaatg aagggcagta
    32401 agtcaagtaa tcactttgaa gtttcaaatc ttaagtttta agttttcttt aaggaaagta
    32461 tattattctg aaggactcta aaatttcgca gccatttatt agtaattgct acagaattcc
    32521 tagtcattac tagaaatgga ctagtttctt tgaataatag aactgcataa ttctcctatt
    32581 ctagaagggg aggaccagta tttcttttat gataggacta gattgtggta taatagagag
    32641 aataagtttt tttagtaaga caaaggagaa aatagatgat ttatgcagga attcttgccg
    32701 gtggaactgg cacacgcatg gggatcagta acttgccaaa acaattttta gagctaggtg
    32761 atcgacctat tttgattcat acaattgaaa aatttgtctt ggagccaagt attgaaaaaa
    32821 ttgtagttgg tgttcatgga gactgggttt ctcatgcaga agatcttgta gataaatatc
    32881 ttcctcttta taaggaacgt atcatcatta caaagggtgg tgctgaccgc aatacaagta
    32941 ttaagaaaat cattgaagcc attgatgctt atcgtccgct tactccagag gatatcgttg
    33001 ttacccacga ttctgttcgt ccatttatta cacttcgcat gattcaggac aatatccaac
    33061 ttgcccaaaa tcatgacgca gtggacacag tggtagaagc agttgatact atcgttgaaa
    33121 gtaccaatgg tcaatttatt acagatattc caaatcgtgc tcacctttat caaggacaaa
    33181 cacctcaaac attccgttgc aaggacttca tggaccttta tggatctctt tctgatgaag
    33241 agaaggaaat cttgacagat gcatgtaaaa tctttgtgat caaaggaaaa gatgtggcct
    33301 tggccaaagg tgaatactca aatctgaaga ttacaaccgt aacagatttg aagattgcaa
    33361 aaagtatgat tgagaaagac tagtaaaatg attaatcaaa tttatcaact aactaagcct
    33421 aagtttatca atgtcaaata tcaggaagag gctattgacc aagagaatca tatccttatc
    33481 cgtcccaact acatggctgt ctgtcatgcg gatcagcgtt actatcaggg aaaacgtgat
    33541 cccaagattt tgaataaaaa gcttccaatg gcaatgattc acgagtcatg tggaaccgtc
    33601 atttctgacc cgaccggaac ctacgaggtt ggtcaaaaag ttgtcatgat tcccaatcag
    33661 tctcctatgc agagtgatga agaattctat gaaaactaca tgacagggac ccatttcttg
    33721 tctagtggat ttgatggctt tatgagagag tttgtttctc tccctaaaga tcgtgtggtg
    33781 gcttatgatg ctattgaaga tacggttgca gccattacag agtttgtcag tgtgggcatg
    33841 cacgctatga atcgtctatt gactcttgct catagcaagc gggagcggat cgccgttatt
    33901 ggagatggaa gtttagcttt tgtggttgcc aatattatca actatacttt gccagaatca
    33961 gagattgtgg ttattggtcg tcattgggaa aagttggaac tcttctcatt tgccaaagaa
    34021 tgctatatta cggataatat tcctgaagag ttggcctttg accatgcttt tgaatgttgt
    34081 ggtggtgatg gtactggacc agctattaat gacttgattc gctacattcg tcctcaggga
    34141 acgattctca tgatgggagt tagcgaatat aaagtcaatc tcaatactcg cgatgcctta
    34201 gaaaagggct tgattttggt tgggtcatct cgttctggtc gcattgattt taaaaatgct
    34261 atccaaatga tggaagtcaa gaaatttgcc aatcgtctta aaaatatcct ttatctagaa
    34321 gaacctgtaa gagaaattaa agatattcat cgtgtctttg caaccgattt aaacacagcc
    34381 tttaaaacag tgtttaagtg ggaagtataa gtactggagg ttaattgtgg agaaaatcat
    34441 taaagaaaaa atttcttcct tacttagtca agaagaggaa gtcctcagtg ttgaacaact
    34501 gggtggaatg accaatcaaa actatttggt caaaacaaca aataagcaat acattgttaa
    34561 attctttggt aaagggacag aaaagcttat caatcgacaa gatgaaaagt acaatcttga
    34621 actactaaag gatttaggct tagatgtaaa aaattatctt tttgatattg aagctggtat
    34681 caaagtaaat gagtatatcg aatctgcgat tacgcttgat tcaacgtcaa tcaagaccaa
    34741 gttcgacaaa attgctccaa tattacaaac tattcataca tctgctaagg aattaagagg
    34801 agaatttgct ccttttgaag aaatcaaaaa atacgaatcc ttggttgaag aacaaattcc
    34861 ttatgccaac tatgaatctg ttagaaatgc agtcttctcc ttagagaaaa gactggctga
    34921 cttaggtgtt gacagaaaat cttgtcatat cgatttggtg cctgaaaact ttatcgaatc
    34981 acctcaagga cgactttatt tgattgactg ggaatattca tcaatgaatg atccaatgtg
    35041 ggatttggct gccctctttt tagagtctga attcacttcc caagaggaag aaactttctt
    35101 atctcactat gagagtgacc aaacaccggt ttctcatgaa aagattgcta tttataaaat
    35161 tttacaagat actatttgga gtctatggac tgtatataag gaagagcaag gtgaagattt
    35221 tggtgactat ggtgtgaatc gttaccaaag agctgttaaa ggtttggctt cttatggagg
    35281 ttcagatgaa aagtaaaaac ggagttcctt ttggccttct atcaggtatt ttctggggct
    35341 tgggtctaac ggttagtgct tatatctttt cgatttttac agatttgtca ccctttgtgg
    35401 tggctgcagc tcatgatttt ttgagcatct ttatcttact agcttttctc ttggtaaaag
    35461 aagggaaagt tcgcctctca attttcttaa atattcgcaa tgtcagtgtt atcatcggag
    35521 ccttgctagc aggccctatc ggtatgcagg ccaatcttta tgcagttaag tatatcggaa
    35581 gttctttagc ttcatctgta tcggctattt accctgcgat ttcagttcta ttggctttct
    35641 tctttttgaa gcacaagatt tcgaaaaata ctgtatttgg gattgtcttg attattggag
    35701 ggattattgc ccagacctat aaggttgaac aggttaattc cttctacatt gggattctct
    35761 gtgctttggt ttgtgctatt gcatggggaa gtgagagtgt tcttagctcc tttgctatgg
    35821 aaagtgaact gagtgaaatc gaagccctct taatccgtca agtgacttcg ttcttgtcct
    35881 atcttgtgat tgtgctcttc tctcatcagt catttactgc agtagccaat ggacaattgc
    35941 taggtctcat gattgttttt gcagcctttg atatgatttc ctacttggct tattatatcg
    36001 ctatcaatcg cttgcaacca gccaaggcta caggcttgaa cgtgagctat gtagtatgga
    36061 cagtcttgtt tgcagttgtt ttcttgggtg caccgctaga tatgctgaca attatgacgt
    36121 cacttgtcgt cattgctgga gtttatatta ttattaaaga ataaaggaga ttcgtgtgaa
    36181 agccatcatc ttagcagcgg gattgggaac tcgcttgcgt cctatgactg aaaatacccc
    36241 taaagccttg gttcaggtta atcaaaaacc tttgattgaa taccaaattg agtttctcaa
    36301 agaaaaagga atcaatgaca tcatcatcat tgttggttat cttaaagaac aattcgatta
    36361 cttgaaagag aaatacggtg ttcgtctcgt tttcaatgat aaatacgctg actacaataa
    36421 cttttactct ctctatcttg taaaagaaga attagccaat agttatgtta tcgatgccga
    36481 taactatctc tttaaaaata tgttccgcaa tgatttgaca cgttctactt attttagtgt
    36541 ctatcgtgaa gattgtacca acgaatggtt cttggtctat ggagatgact acaaggttca
    36601 aaacattatt gttgatagca aggcaggtcg catccttagt ggtgtatcct tctgggatgc
    36661 tccaacagca gaaaagattg tcagctttat cgataaggct tatgcaagcg gcgaatttgt
    36721 tgatctctat tgggacaata tggttaagga taacatcaaa gagctagatg tctatgttga
    36781 agaattagaa ggcaatagca tttatgagat tgatagtgtc caagactatc ataaattaga
    36841 agaaattctt aaaaacgaaa attaaaagct tccaacatct gacaaaatag tcggatgttt
    36901 ttttgatttt ttacgaactt ttacgaatag atagatgagt agaaaaagaa atggagttat
    36961 ttatgaaaat cacaaactat gaaatctata agttaaaaaa atcaggtttg accaatcaac
    37021 agattttgaa agttctagaa tacggtgaaa atgttgatca ggagcttttg ttgggtgata
    37081 ttgcagatat atcaggttgc cgtaatccag ccgtttttat ggaacgttat tttcagatag
    37141 acgatgcgca tttgtcgaaa gagtttcaaa aatttccatc tttctctatt ttagatgact
    37201 gttatccttg ggatttgagt gaaatatatg atgcgcctgt acttttattt tacaagggaa
    37261 atcttgacct cctgaaattc ccgaaggtag cggtcgtggg cagtcgtgct tgtagcaaac
    37321 agggagctaa atcagttgaa aaagtcattc aaggcttgga aaatgaactg gttattgtca
    37381 gtggtctggc caagggcatt gacacagcag ctcatatggc agctcttcag aatggcggaa
    37441 aaaccattgc agtgattgga acaggactgg atgtgtttta tcctaaagcc aataaacgct
    37501 tgcaagacta catcggcaat gaccatctgg ttctaagtga atatggacct ggcgaacaac
    37561 ctctgaaatt tcattttcct gcccgtaatc gcatcattgc tggactttgt cgtggtgtga
    37621 ttgtagcaga ggctaagatg cgttcaggta gtctcattac gtgtgagcga gcaatggaag
    37681 aaggacgcga tgtctttgct attcctggta gcattttaga tggactatca gacggttgcc
    37741 atcatttgat tcaagaagga gcaaaattgg tcaccagtgg gcaagatgtt cttgcggaat
    37801 ttgaatttta aaaatgacct aagctaaaat tctaagaaaa aatcaatttt aagagaaaat
    37861 gaacccaaca tttccataat aaaacgcata ttagcaagtt tttaacactt gataatatgc
    37921 gttttttcta agtggattag tagagtagag gatttttctc atataatact cttcgaaaat
    37981 ctcttcaaac tacgtcagct tccatctgca acctcaaaac agtattttga gctgacttcg
    38041 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgtggctag cttcctagtt
    38101 tgcgctttga ttttcattga gtataaggga aagtatagtg aattgaaata agatgtgaac
    38161 aactctatca ggaaagtcaa attaatttat agaaatattt tagcagccaa ggtgcactgt
    38221 tatagattca atacactata atttagtgta attgagaaag gagaaatgat tgtgattgat
    38281 gttggctagg ttatgttcaa tgattcctac cgtctcaaat cttgtcagta aggaaaaata
    38341 aattcttcaa aagtagagat tacaaggttt gtttaagaaa gaattcaaag accttgacaa
    38401 ataaaaataa aatggttatt ataagaaatg gtctaaaata gatgatgata cttttcgaaa
    38461 atctttttac gtcagctcag ctttgccttg ctgtgttttg agcaagctac ggttagcttc
    38521 cgagtttgat tttcatttac tagaaatgaa actgatgaga gatatcagta gacatttgag
    38581 tcaggatatt atggaaaatg ataaaaagag ctcgtgagat tggcatatca gactactaaa
    38641 gtattgagtt tgttaggatt ttagcgacta gttagctggg aaaggaagat atttgtgaca
    38701 aataataaac tgtattcgtt gatagaattt agaaataaaa tatatgaaga attagaactt
    38761 tccagaagtg atttagcgat tttactatgt gccatgctta tcgcctctat cggattaaat
    38821 atggattcga ctcccgtgat tattggagcc atgttaatct ctcctttgat gacacctatt
    38881 ctgggagtgg ggctctctct agctatattt gattttaaat tgttaagaaa atcttttaaa
    38941 atattagcta ttcaaattct tgccagtcta atagcttcaa cactttattt ttatctttct
    39001 cccatttcgt atgctagttc ggagattgtt gctagaacct ctccgactat ttgggatgtt
    39061 ctcattgctt ttgtaggagg gatagcaggt attattggtg ctaggaaaaa agagaccaat
    39121 aatattgttc ctggtgttgc tattgcaacc gccttgatgc ctcctctttg tacagtaggt
    39181 tatgctattg cttctgctaa tctaaaattt atcataggct cctcttacct attcctcatc
    39241 aattgtagct ttattgtcat tgcgacttat ataggtgtta ggttgatgat ggttaagaaa
    39301 cattatttta aagataatga agaagactct aaaatgcgta ggattttgct tctagttgct
    39361 gttttgctga tgattccgag tttcatctct gcaacgactt tagtgagaga aacgttgaaa
    39421 aaagagtccc ttaagaaatt tatatcagag cagtttcagg ggcataatat tttgaaaaaa
    39481 acctattcta aaaagactca taccctaaag ctaaccatct caggaaatta tttgacagaa
    39541 gaagaactcg atatgatttc aagtaagaga ggtgactatg gtttaagtga tgtttctgtt
    39601 caagtttcac aattgtctga ttcagaacaa cttagtaagg aagagctggt ggagtatttc
    39661 ttccagtata tcaaggataa ggaagcaaaa gaaaaggaga aagctaataa atttgataca
    39721 gagtctgagg agcaataatt tcttgagaat agctggtttc tctcgtgagt cttctatgta
    39781 tatcaaagga agactgaggt tttaagtata aaacttttct tctattatag tagctaagtc
    39841 ttgacagggt tcaaaaaatg gtttacactt tataaagttt attactttga aaaggtgtga
    39901 tactgtggct acggcaacaa aaaagaaaaa atcaacagtt aaaaaaaatc tagtcatcgt
    39961 ggagtcgcct gctaaggcca agacgattga aaaatatcta ggcagaaact acaaggtttt
    40021 agccagtgtc gggcatatcc gtgatttgaa gaaatccagt atgtccgtcg atattgaaaa
    40081 taattatgaa ccgcaatata ttaatatccg aggaaaaggc cctcttatca atgacttgaa
    40141 aaaagaagct aaaaaagcta ataaagtttt tctcgcgagt gacccggacc gtgaaggaga
    40201 agcgatttct tggcatttgg cccatattct caacttggat gaaaatgatg ccaaccgtgt
    40261 ggtcttcaat gaaatcacca aggatgcagt caaaaatgct tttaaagaac ctcgtaagat
    40321 agatatggac ttggtcgatg cccaacaagc tcgtcggatc ttggatcgct tggtagggta
    40381 ttcgatttcg cctattttgt ggaagaaggt caagaagggc ttgtcagcag gtcgcgttca
    40441 gtccattgcc cttaaactca tcattgaccg tgaaaatgaa atcaatgcct tccagccaga
    40501 agaatactgg acagttgatg ctgtctttaa aaagggaacc aaacaatttc atgcttcctt
    40561 ctatggagta gatggtaaaa agatgaaact gaccagcaat gatgaagtca aggaagtctt
    40621 gtctcgtctg acgagtaaag acttttcagt agatcaggtg gataagaaag agcgcaagcg
    40681 caatgctcct ttaccctata ccacttcatc tatgcagatg gatgctgcca ataaaatcaa
    40741 tttccgtact cgaaaaacca tgatggttgc ccaacagctc tatgaaggaa ttaatatcgg
    40801 ttctggtgtt caaggtttga ttacctatat gcgtaccgat tcgactcgta tcagtcctgt
    40861 agcgcaaaat gaggcggcaa gcttcattac ggatcgtttt ggtagtaagt attctaagca
    40921 cggtagcaag gtcaaaaacg catcaggtgc tcaggatgcc catgaggcta ttcgtccgtc
    40981 aagtgtcttt aatacaccag aaagcatcgc taagtatctg gacaaggatc agctcaagct
    41041 atataccctt atctggaatc gttttgtggc tagccagatg acagcggccg tttttgatac
    41101 catggctgtt aaattgtctc aaaaaggggt tcaatttgct gccaatggta gtcaggttaa
    41161 gtttgatggt tatcttgcca tttataatga ttctgacaag aataaaatgc taccagatat
    41221 ggctgttgga gatgtggtca aacaggttaa tagcaaacca gagcaacatt tcacccaacc
    41281 gcctgcccgt tattctgaag caacactgat taaaacctta gaggaaaatg gggttggacg
    41341 tccatcaacc tatgcgccaa ccattgaaac cattcagaaa cgttattatg ttcgcctggc
    41401 agccaaacgt tttgaaccga cagagttggg agaaattgtc aataagctca tcgttgaata
    41461 tttcccagat atcgtaaacg tgaccttcac agctgaaatg gaaggtaaac tggatgatgt
    41521 cgaagttgga aaagagcagt ggcgacgggt cattgatgcc ttttacaaac cattctctaa
    41581 agaagttgcc aaggctgaag aagaaatgga aaaaatccag attaaggatg aaccagctgg
    41641 atttgactgt gaagtgtgtg gcagtccaat ggtcattaaa cttggtcgtt ttggtaaatt
    41701 ctacgcttgt agcaatttcc cagattgccg tcatacccaa gcaatcgtga aagagattgg
    41761 tgttgagtgt ccaagctgtc atcagggaca aattattgag cgaaaaacca agcgtaatcg
    41821 ccttttctat ggttgcaatc gctatccaga atgtgaattt acctcttggg acaagcctgt
    41881 tggtcgtgac tgtccaaaat gtggcaactt cctcatggag aaaaaagtcc gtggtggtgg
    41941 caagcaggtt gtttgtagca aaggcgacta cgaggaagaa aagattaaat aagaggaggg
    42001 gcccgaaagt aaatttcagg ctccttttgg ttagaacttg acaaaataca tcattttatg
    42061 cgaaactaga agaagattat tttaactagg agaagttatg cgtcttatct atctgataat
    42121 tggtttttta tcactggcct tggctattgt tggggttgtt ttacccttgt tgccgacaac
    42181 gcctttcctt ttgttgtcta ttgcttgttt ctccagaagt tccaagcgtt tcgaagactg
    42241 gctttatcat accaagctct atcaaacata tgtagctgat tttcgcgaga ctaagtctat
    42301 tacgcgtgaa cgaaagaaaa aaatcatcgt ctctatctac gtcttgatgg gaatttctat
    42361 ttattttgca cctcttttac cagtcaaaat cggtctgggt gctttgacca tctttatcac
    42421 ttattatctt ttcaaggtca ttccagacaa agaatagtta aaacagtagt tatttgcctt
    42481 gataaaattg aaagcatatt cataataata tgatataata aatttgaagt aatattcaag
    42541 gagaatcaaa tgatttacga attttgtgct gaaaatgtga ctttacttga aaaagcgatg
    42601 caggctggag ctcgtcggat tgaactctgt gataatctag cagttggtgg gacaacaccc
    42661 agctatggag tgactaaggc agcggttgaa ctggcagcta actacgatac aaccatcatg
    42721 accatgattc ggccacgtgg tggtgacttt gtctataatg acctagaaat tgctatcatg
    42781 ctagaagaca ttcgtttgac tgctcaggct ggaagtcaag gggttgtatt tggaacttta
    42841 actgctgata aaaagttgga taagcctaat ctggaaaagt taattgctgc atcaaaagga
    42901 atggaaattg tctttcacat ggcctttgat gaactaagtg atgaagatca accggaagct
    42961 attgactggc tcagtcaagc cggtgtcact cgtatcctaa ctcgtgctgg tgtgtctggc
    43021 gactccttag aaaaacgttt tgttcactat cacagaattt tggagtacgc taaaggtaaa
    43081 attgaaattc taccaggtgg ggggattgac cttgaaaacc gtcaaacctt tatcgaccag
    43141 gtgggggtaa cacaattgca tggtactaag gttgtttttt aaaaaataga aaggaactgc
    43201 tagctttggg tagcagtttt cacttatgtt tgaaattttt aaatcctatc aatttaatca
    43261 agaaaaggct catgattatg gttttataga aaatagcgaa gtctggacat atagttgcca
    43321 gattttgcaa ggtgactttg tcatgactgt gtccatcact gctgataatg tgaactttca
    43381 agtctttgac caagagactg gtgacctcta tcctcacgtt catatggaaa gcatgagggg
    43441 aagttttgtc ggaaatgtcc gtgaggcttg tctggagatt ctttaccaga ttcggaaggc
    43501 ttgttttgat gtgcaagatt ttatctgtca tcagactaag cgtatcatga ctcaagttca
    43561 ggaaaagtat ggaaaccagt tggagtatct gtgggaaaaa tcgcctgata cagctgtatt
    43621 gcgccatgaa ggcaatcaaa agtggtatgc cgtcttgatg aaaatctctt ggaataagct
    43681 ggaaaagggc agagaaggac aagtggaagc agtcaacctc aagcatgacc aagtagctaa
    43741 tttgctttca caaaagggga tttatccagc cttccatatg agcaagcgct actggattag
    43801 tgtgtccctt gatgatactt tatcagatga agaagtactg gaattgatag aaaaaagttg
    43861 gaacttaacc tctaaaaaat gaaatatttt aataattttc atgaactttc aattagctga
    43921 atattcttta ctgaagaaat tttcagaaaa tataggattt accacaccag aggaatgtgg
    43981 tgccatcttc aaatacctga ttgagaatgt caagacggat cgtcagatca tctattcgcc
    44041 tcactgtcat gatgacctcg gaatggcagt ggcaaatagc cttgctgctg tcaagaatgg
    44101 tgcaggacgt gttgaaggga ctatcaatgg tattagggag cgagctgaaa atgctgcttt
    44161 ggaagaaatt gcagtggctc tcaatattcg ccaagattac taccaagtag aaaccagtat
    44221 tgtcctaaat gagaccatca atacgtcaga aatggtttct cgcttctctg gtattccagt
    44281 tcctaaaaac aaagccgtcg ttggtggcaa taccttctcc cacgaatctg gtattcacca
    44341 agatggagtc cttaaaaatc ctctcactta tgagatcatc acacctgaat tggttggtgt
    44401 taagattccg cttggaaaat tatctggtcg ccatgctttt gttgagaaac tgagagaatt
    44461 ggccctagat tttacagaag aggatatcaa accactcttt gctaagttca aggcactggc
    44521 cgataagaag taagaaatca cagatgcaga tactcgagct ttggtagctg gaaccatggt
    44581 tgaaaatcca gaaggcttcc actttgatga tttacaactt caaactcatg cagataatga
    44641 cattgaagcg ctcgttagcc tagccaatat ggatggtgag aaagtcgaat ttaatgcgac
    44701 agggcaaggt tccgttgaag caatctttaa tgctatcgat aagttcttta accaatctgt
    44761 tcgtttggtg tcctacacta tcgatgcggt aacagatgga atcgataccc aggatcgggt
    44821 tttggtcact gttgaaaaca gagatacaga aaccatcttt aatgcagcag ggcttgattt
    44881 tgatgtgttg aaggcttctg ctattgtcta tataaacgct aatacctttg ttcaaaaaga
    44941 gaatgcaggt gagatgggac gcagtgtttc ttaccacgat atgcctagtg tgtaaaggag
    45001 aaggctatgg caaagaaaat agtagctcta gcaggagacg gaattggccc agaaatcatg
    45061 gaggttggtt tagaagttct ggaggctcta gctgaaaaaa caggttttga ctatgagatt
    45121 gacagacgac cgttcggagg tgcagatatt gatgcagcag gacctccctt acctgatgaa
    45181 acccttaagg caagtaggga agcagatgct atcctactag cagctatcgg tagtcctcag
    45241 tatgatggag cagtggttcg ccctgaacag ggcctgatgg ctctccgtaa ggaactcaat
    45301 ctttacgcta atattcgtcc tgtaaaaatc tttgacagtc tcaagtattt gtcaccactc
    45361 aaactggaac gaattgctgg tgtagacttt gtcgtggtgc gtgaattgac aggcgggatt
    45421 tactttggag atcatattct tgaagagcgc aatgcgcgtg atatcaacga ctatagctat
    45481 gaggaagtgg agcggattat tcgcaaagcc tttgaaattg caagaaatcg cagaaaaatc
    45541 cttactagta tcgataagca aaatgttcta gcgacctcaa aactctggcg gaaagtagct
    45601 gaggaagtcg cacaggattt cccagatgta accttggaac accagctggt agactcagct
    45661 gctatgctta tgattaccaa tcctgctaag tttgatgtta ttgtaacgga gaatcttttt
    45721 ggagatattt tatctgatga atcaagcgtc ttatctggta cacttgaggt tatgccatca
    45781 gccagtcatt ctgaaaatgg accaagtctc tatgaaccta ttcacggttc agcacctgat
    45841 attgcaggtc aaggaattgc caatcctact tccatgattt tatcagttgc catgatgttg
    45901 agagatagtt tcggacgtta tgaggatgca gagcgtatca aacgtgctgt tgagacaagt
    45961 ctggcggcag gaattttaac gagagatata ggaggtcagg cttcaacaaa ggaaatgacg
    46021 gaagctatta ttgcaaggtt atgaagttag acgaaaaaat tactctagtc cttttgattt
    46081 ggaatgtcat cattttcttg atttatggca ttgacaaatt caaggcaaga agaagagctt
    46141 ggcgcatccc agagaaaatc ttactcattt tagcccttac ttgtggtggt tttggggcct
    46201 ggttagctgg aattactttt caccacaaga ctcgaaaatg gtactttaaa acagtttggt
    46261 ttcttgggat ggtgaccaca ctagtagcct tatattttat ttggaggtaa tggatggcag
    46321 ggtcttcgag ggaacacgct gcttgggctc tagcggacta tggttttaag gtcgtgattg
    46381 caggatcttt cggtgacatt cattacaata atgaactcaa taatggcctg ttgccaatcg
    46441 ttcagcctag agaggttaga gagaaattag cccagctaaa accaaccgac caggtaactg
    46501 tggacttgga acaacaaaaa atcatctcac cagttgaaga attcaccttc gagatagata
    46561 gcgagtggaa acataaactc ctaaatagtt tggatgatat cggtattacc ttgcagtatg
    46621 aagagttgat tgttgcttat gaaaaacaac gaccagccta ctggcaggat tagaaaaaat
    46681 agaaaaggaa atatagtaaa ctgaaataag atgtaaacaa atgaattaga gcttaacatc
    46741 catttccagc aattttttag aaactacagt ggactattct ggattcaaca cattataaaa
    46801 ttatgacaaa acacattcac aagaaggcta cgacatttta aaaggtgagg gcggatgtat
    46861 cgtttgccct actaaagttg gttacattat catgaccagc aacaaggcag gacttgagcg
    46921 taagttcgca gccaaagaac gtaagcgtaa caaaccaggt gttgttctct gcggtagcat
    46981 ggatgaactt tgcgctttag cgcaactcaa cccagaaatt gaagcattct actaaaaaca
    47041 ttgggatgaa gatattcttc ttggttgtat ccttccttgg aaaccagaag tctttgaaaa
    47101 actcaaagca tacggggatg gccgtgaaga acttatgact gatgtacgtg gtactagctg
    47161 ttttgttatc aagtttggaa aagcaggtga acaattggct gccaagcttt gggaagaagg
    47221 taaaatggtc tacgcctcat ctacttcaat gacaaaacga ttgaaactcg ctatgagagc
    47281 aaggtgtaat ggtgtctatg gtcgataagg acggcaaact catcccagaa caaggaggag
    47341 cacgttcaac ctcaccagca ccagttgtga tccgtaaagg gcttgacatt gataaaatca
    47401 tgatgcacct gtcagatact tttaactcat gggactaccg tcaggttgag tattattagg
    47461 atagagaaga agtctagtgt taaggacatt acagctcata atactaggct tttttataga
    47521 aattcttttc tttttctata ggatatggta ttctatgtag aaaatatatg ttaataagta
    47581 atgccaatat ttaaacatca ttagtaaaag gagttagatt gatgaataaa agaaaagtta
    47641 gtttagaaga tttttataaa tggtatagtc taaataaaga agagttatta aataaggcaa
    47701 ctgttggtga aaagtttaat gataaattaa aagaagagtt tctccaggaa tggcctttgg
    47761 ataggatttt aacaatgtca atcgatgaat atgtaatagg aaagggacag caaaataagt
    47821 ctttatgcta cgctcttgag aagggaaaat acaaaaatct atttcttgga atttctggtg
    47881 gctcagcttc aaaatttggt atttattgga ataaaaaaac aaacaaatat aaagatcaag
    47941 ctaataatga gatttcagag ttggatcagc gattttcaaa attaaaatca gatttgtatg
    48001 aaattatcaa agaaggtatt cgttttaact ttgaaaatcc tatttttgat atgaaaagat
    48061 caacaaatga atttattggt cgttctgcta tggtgacaaa attactttgt atctattctg
    48121 ggggagatcc tttctttggt gtaaatatta atagtcagaa agaattttgg aaccactttg
    48181 tttctcagac aaatcaaggt ggaccttatc tgcaaaatca taaaataatt gaactggtgt
    48241 ccaaaactta tcctgagttg gagccatcga aattaggaac tatgcttttt gagtattcta
    48301 agctttttat ggaaaataag gaagacaata gtacaatgga ttcatcaaac aattttcgtc
    48361 atcaattaac tcaatctcta ttaaagtctc caaaccttat ccttcgtggt gctcctggca
    48421 caggaaagac ttatcttgct aaagaaattg ccaaagaatt aacggatggc aacgaagacc
    48481 aaatcggatt tgtacaattt cacccatcct atgattatac ggattttgta gaaggtttaa
    48541 gaccagtatc aaatggggat ggagctattg agtttaggct acaggacggt atttttaaag
    48601 atttttgtca gaaagcaaaa gaaacccaat tgattggagg acaagataat tttgatgagg
    48661 cttgggattc ttacttagaa tatataaatg ttgctgaaga aaaagaatat ataacaaaaa
    48721 catcttactt atctgttaat agtagacaaa atttgtcagt aaattatgat agtggtgttc
    48781 caggatggtc actacctagc aaatatgttt acgagttgta taaagataaa aattataata
    48841 agcaagaata ctacaaaagt ggtggaaaaa ctgtcctaga aacattgaga aagagatttg
    48901 gtttgaaaga ctatgtttcc ccaacagaaa ttgatactga taagaaattc gtcttcatca
    48961 tcgatgaaat caatcgtggg gagatttcta agatttttgg cgaactcttt ttctctatcg
    49021 accctggcta tcgtggtgaa aaaggaagtg tttctaccca atatgcaaat ctacacgaaa
    49081 ctgatgaaaa gttctatatc cccgaaaatg tttacatcat cggaactatg aatgatattg
    49141 atcgttcagt ggataccttt gattttgcta tgcgtcgtcg ttttcgtttt gttgaagtta
    49201 ctgccgaggg tcaagttggc atgttggata aagagctgaa tatccatgca gaagaagcaa
    49261 aaattcgtct aagaaacttg aacgctgcta tcgaaaatgt tcaggaatta aacagtcatt
    49321 atcatattgg accaagttat tttcttaagt tgaaggatgt agattttgac tatgaattac
    49381 tctggtccga ttatattaag cctctcctag aagactactt gcgaggttct tatgatgagg
    49441 ttgaaacttt ggaaactttg aaaaaagcat ttgaactgac aaataatgat caaactggtc
    49501 aacaagatac tggtgataat gatgcggatt actgataatc aatacaagat tattaaagaa
    49561 aaatttgttg aagaatatcc gaaactaagc aatcttcttt tagacagaac cttggaaagt
    49621 ctatcccaag atgaacgtat tttcattttt ccaaatgatt tgactcatac tcctgatttg
    49681 gataaggacc aaaagatttt tgaaacagtc aatcagaaaa tcaagacagg gaacgtgatt
    49741 ggttttcttg gatatggtca ggaaagatta acgatttcct cacgattttc tgatgagagt
    49801 aatgaccatt ttttgcatta tctcttaaac aaggttcttc atatcaatct cactagttta
    49861 gatgttgctt tgtctcgtga agagaggctt tatcaacttt tgatgtatct cttccccaag
    49921 tatctacaag ctgctattcg aaaaggtctt tataaggaat accagagatt ttctcataac
    49981 gacagtcatg ttaagggagt gattgatgta agaaaccatc tcaagaaaaa tcttcctttc
    50041 acgggaaata ttgcctacac aacgagagag ttcacctatg ataatcccct catgcagttg
    50101 gtccgtcaca ctattgaata cattaagaat cagaaaagca ttggtcaagg ggtactagat
    50161 aatctctcaa ctagtcgtga aaacgtatct gaaatcgtgc gtgtaacgcc ctcttataaa
    50221 ctagctgatc gtgctaagat tattcgggga aatcaatcta aacctatacg tcatgcatac
    50281 tttcacgagt acagaaactt acaagaactt tgtctgatga tcctaaacca agaaaagcac
    50341 ggtttagggt atcaagatca aaaaatctat ggtattctct ttgatgttgc ctggctttgg
    50401 gaagagtatg tttacacctt gttgccaaaa ggttttgtac atcccagaaa taaggataag
    50461 acggatggaa tttcagtatt ttctgttggg aaacgaaaag tatatccaga tttttatgac
    50521 agagaacgaa agattgttct agatgcaaaa tataaaaaac tggaattgac tgaaaaagga
    50581 atcaaccgtg aggacttatt ccagctgatt tcctattctt atattttaaa agctgagaag
    50641 gctggactga tttttcctag tatggagcag tcagtaaata gtgaaatagg aaaagtagct
    50701 ggctatggag ctcaattgaa gaagtggtct attcgaatcc ctcagaatgc ctcattctat
    50761 agtacatttt gtaaaatgat ggaaaattca gaagaaaatt ttaaagcgat tattgatgaa
    50821 gaagtgggga gaaaataatt tcccctcttt cttttatttt taacacaagt aaaacccgaa
    50881 cgatatattt taattcataa aataatttga caaaaactgt actttggttt ataataaatt
    50941 aaggaaacgt cggaaaaggc gtagtgatgc aagagcatag gtaggtcatt acaaaagaaa
    51001 cgagacatcg atatgttaaa tgaatttcca atttttgatt acgaagatat tcaattgatt
    51061 ccaaataaat gtgtcattaa aagccgtgca gaagcggata caagtgtcac tttaggaaat
    51121 cacaccttta aactacctgt tgtgccagcg aatatgcaga cgattttgga tgaaaatgta
    51181 gcagagcaac tggctaaagg tggttacttc tacattatgc accgttttga tgaggcagga
    51241 cgcattcctt ttattaaacg aatgcacgat caagggctca ttgcttctat ctctgtcggt
    51301 gttaaggatt atgagtatga tttcgttaga cagctcaaag ctgatgctcc tgagtatatc
    51361 actattgata ttgctcatgg tcatgcggat agcgtgattt ctatgattca acacatcaag
    51421 aaagaattgc cagatacctt tgtcattgct ggaaatgtgg gaacaccaga agctgtgcgt
    51481 gaattggaaa atgctggtgc ggatgctact aaggtcggaa tcggtcctgg taaggtttgt
    51541 atcaccaagg ttaagactgg ttttggtaca ggtggttggc agttggctgc tctacgctgg
    51601 tgtgccaagg ctgcgcgtaa accgattatc gctgatggag gaattcgtac tcacggtgat
    51661 attgctaagt ctatccgctt cggtgctagc atgatcatga ttggttccct ctttgcagga
    51721 cacattgaaa gtccagggaa aacgattgaa gtcgatggtg aacagttcaa agaatattat
    51781 ggttcagcct cacaatatca aaaaggtgct tacaaaaatg tggaaggcaa acgtatcttg
    51841 cttcctgcta aaggtcatct gcaagacact ttaactgaga tggaacaaga ccttcaaagt
    51901 gctatttctt atgcaggtgg acgtcaggtt gctgacctta aacacgttga ttatgtgatc
    51961 gtgaaaaact ccatctggaa tggggatgct tcccactaag acggggtctt tgaccaaaaa
    52021 acttgttatt agagcaaatt tctgttataa taaaacaagt ttccaccctt agtgtaatgg
    52081 atatcacgta agattccggt tcttgagatg ggggttcgat tccctcaggg tggatgtaaa
    52141 catcctaaaa agcctttaat agggcttttt tctttatcct gacccaaatt tgccgctaaa
    52201 actgagaatc tctgtctaaa gaattcccaa atgctttcca gtcccgtttt agagtgactc
    52261 agggggcttt ttttgatata ataaaaagga ctattatcag ttagaaagag gttggtatga
    52321 aagaattaca aactgtacta aagaatcatt ttgcaatcga atttgcagac aaaaatttac
    52381 tggaaactgc ctttactcat acgagttatg ccaatgagca ccgcctctta aaaatttcac
    52441 acaatgaacg cttggaattt ttaggagacg ctgttctaca gttattgatt tcagaatatc
    52501 tatataaaaa atatcctaaa aagcctgaag gtgacctatc aaaactccgt gctatgattg
    52561 tccgtgagga gagtttagct ggttttgcgc gtgattgcca gtttaaccag tttatcaagt
    52621 tgggtaaagg ggaagaaaaa tcaggtggtc gcaatcgtga caccattctt ggtgatgcct
    52681 ttgaagcctt tcttggtgcc cttcttttgg ataaggatgt ggccaaggtc aaggaattta
    52741 tctatcaagt catcattcct aaggttgaag caggcgagtt tgagatgatt acagactata
    52801 aaacccatct ccaagagttg cttcaggtca atggtgatgt ggctattcgt tatcaggtga
    52861 tttctgaaac agggcctgct catgataagg tctttgatgt agaagttctt gttgaaggta
    52921 agagcatcgg tcaaggccaa ggtcgttcta agaaattagc agagcaggaa gctgccaaaa
    52981 atgccgttga gaaggggctg gattcatgta tttaaaggaa atcgaaattc aggggttcaa
    53041 gtcttttgct gataagacca aggtcgtttt tgaccaaggt gtgacggcag ttgttggacc
    53101 caatggatct ggaaagtcca atattacaga aagtctgcgt tgggctttgg gggagtctag
    53161 tgtcaagagt ctccgtgggg gcaagatgcc ggatgtcatc tttgctggaa ccgaaagtcg
    53221 caaaccgctc aattatgctt ctgtagttgt gactctggat aatcatgacg gatttatcaa
    53281 ggatgcaggt caagaaatca gggtggaacg ccatatctat cgtagtggag atagcgaata
    53341 caagattgac ggcaagaaag tccgtctgcg tgatattcat gacctcttct tggatactgg
    53401 attgggacga gattccttct ctattatttc ccaagggaag gttgaggaga tttttaattc
    53461 caagcctgag gaacgacgag ctatttttga agaagctgct ggagttttaa aatacaagac
    53521 tcgcagaaaa gaaaccgaga gtaaactgca gcaaactcag gataatctgg accgcttaga
    53581 ggacattatc tacgagttgg ataatcaaat caagcctctt gagaagcaag ctgagaatgc
    53641 ccgtaagttt ttagacttgg aaggacaacg taaggctatt tatttagacg ttctggttgc
    53701 tcaaatcaag gaaaataagg ctgaactaga gtcgacagaa gaagagttga ctcaggttca
    53761 agaactcttg atgagttatt accaaaagcg tgaaaaatta gaagaagaaa atcaaactct
    53821 taaaaagcaa cgccaagatt tacaggctga aatggccaaa gaccaaggca gtttgatgga
    53881 cttgactagt ctgattagtg atttagaaag aaaattagcc ctatcgaaac tggagtccga
    53941 gcaagtggcc ttgaatcaac aggaggcaca agcccgtttg gctgctttgg aggataagag
    54001 aaattcactc agcaaagaaa agtctgataa agaaagctct ttagctctgt tagagggaaa
    54061 tctagtccaa aataatcaaa aactcaatcg tttagaagct gaattgctgg ctttttcaga
    54121 tgatcctgat cagatgattg agcttttgcg tgaacgcttt gtggcgcttt tacaagaaga
    54181 agcggatgtc tcaaaccaac tgacccgcat cgagaatgag ttggaaaata gtcgtcagct
    54241 ttctcaaaaa caagcagatc aactagaaaa gctgaaagag caattggcta tagctaaaga
    54301 gaaggctagt cagcaaaagg aagagcttga aactgccaag gagcaggttc agaaattatt
    54361 ggctgactat caagctattg ccaaggagca agaggagcaa aaaacttcct atcaagctca
    54421 acaaagtcaa ctctttgacc gtctggatag tcttaaaaac aagcaggcta gagctcaaag
    54481 tttggaaaac atccttagaa atcacagtaa cttttatgca ggtgtaaaga gtgttctcca
    54541 agaaaaagac cgccttggtg ggattattgg tgctgttagt gagcatttga cctttgatgt
    54601 gcattatcaa actgccttag agattgcact tggagccagc agtcagcata tcatcgtaga
    54661 agatgaagag tcggcaacca aagctattga tttccttaaa cgaaacagag ccggtcgtgc
    54721 aaccttcctt ccgttgacaa caatcaaggc tcgtacgatt tctagccaga atcaagatgt
    54781 tatcgctgta agcccaggtt tccttgggat ggcagatgag ttggtgactt ttgatactag
    54841 actggaagcc attttcaaga atttgctagc tacgacggct atttttgata ctgtagagca
    54901 tgcgcgtgca gcagctcgcc aagttcgtta tcaggttcgt atggtgacat tggatgggac
    54961 agaattacgc acgggtggtt cctatgcggg tggtgccaat cgccaaaata acagtatttt
    55021 catcaagcca gaactggagc aattacaaaa agaaattgct gcagatgaag caagcttggg
    55081 ttcagaagaa gcggctttga agaccttgca agaccagatg gctacattga cagaaagatt
    55141 agaagccatc aaatctcaag gagaacaggc acgtattcag gagcaaggct tgtccctcgc
    55201 ttatcagcaa actagtcagc aagttgaaga actggaaact ctttggaaac tccaagaaga
    55261 ggaaaaagat cgtctttctg atggagattg gcaagcagac aaggaaaact gccaagagcg
    55321 tcttgctgca atcgccagtg acaagcaaaa tctggaagct gagattgaag agattaagtc
    55381 taataaaaat gccatccaag aacgctatca aaacttgcag gaagagctag cgcaagctcg
    55441 tttgcttaag acagaactgc aagggcaaaa acgttatgaa gtggctgata ttgaacgctt
    55501 aggcaaggaa ttggacaatc ttgattttga acaagaggaa atccagcgcc ttcttcaaga
    55561 aaaggttgac aatcttgaga aggttgatac agaattgctc agtcaacagg cggaagaatc
    55621 caaaactcag aaaacgaact tccaacaagg tttgattcgc aaacagtttg agttggatga
    55681 tatagaaggt cagctggatg atattgctag tcatttggat caggctcgcc agcagaatga
    55741 ggagtggatt cgcaagcaaa cacgtgctga agccaagaaa gaaaaggtca gcgagcgctt
    55801 gcgccatcta caaagtcaat taacagacca gtaccagatt agctatactg aagctctaga
    55861 aaaagcgcat gaattggaaa acctcaatct ggcagagcaa gaagttaagg atttagagaa
    55921 ggctattcgc tcactgggtc ctgtcaatat agaagctatt gaccagtacg aagaagttca
    55981 cagccgtctg gatttcctca atagccagcg agatgacatt ttgtcagcga aaaatctgct
    56041 tcttgagact attacagaga tgaatgatga ggtcaaggaa cgctttaaat caacctttga
    56101 agctatccgt gagtccttta aagtgacctt caagcagatg tttggcggag gtcaagcgga
    56161 cctgattttg actgagggag acttgctgac agctggggtt gagatttctg ttcaacctca
    56221 aggtaagaaa atccagtccc ttaatctcat gagtggtggt gaaaaagctc tatcggctct
    56281 tgccttgctc ttctccatta ttcgtgtcaa gactattcca tttgttatct tggatgaggt
    56341 ggaagctgcg ctggatgaag ccaatgttaa acgttttggg gattacctca accgctttga
    56401 caaggacagc cagtttatcg tcgtaaccca ccgtaaggga accatggcag cggctgattc
    56461 catctatgga gtgaccatgc aagaatcggg tgtttcaaag attgtttcag ttaagttaaa
    56521 agatttagaa agtattgaag gatgacaatt aaactagtag caacggatat ggacggaacc
    56581 ttcctagatg ggaatggacg ctttgatatg gatcgtctca agtctctctt ggcttcctac
    56641 aaggaaaaag ggatttactt tgcggtggct tcgggtcggg gatttctgtc tctggaaaaa
    56701 ttatttgctg atgttcgtga tgacattatt ttcatcgcgg aaaatggcag tttggtagag
    56761 tatcaaggtc aggacttgta tgaagcgact atgtctcgtg acttttatct ggcaactttt
    56821 gaaaagctga aaacgtcacc ttatgtagat atcaataaac tgctcttgac gggtaagaag
    56881 gggtcatatg ttctagatac ggttgatgag acctatttga aagtgagtca gcattataat
    56941 gaaaatatcc aaaaagtagc gagtttggaa gatatcacag atgacatttt caaatttaca
    57001 accaacttca cagaagaaac gttagaagct ggtgaagctt gggtcaatga taatgtccct
    57061 ggtgtcaagg ctatgacaac tggctttgaa tctattgata ttgttctgga ctatgtcgat
    57121 aagggtgtag ctattgttga attagctaaa aaacttggta tcacaatgga tcaggtcatg
    57181 gcttttggag acaatcttaa tgacttacat atgatgcagg ttgtgggaca tcctgtagct
    57241 cctgaaaatg cacgacctga aattttagaa ttagcaaaga ctgtgattgg tcaccataag
    57301 gaacggtcgg ttatagctta tatggagggc ttataatggc agatataaaa ttgattgcat
    57361 tggacttgga cgggaccttg ctgactactg ataaaaggct gacggatcgt accaagtcaa
    57421 ccttgaaagc tgcgcgtgat cgtggtatca aggtcgtatt gacaactggt cgtcccttaa
    57481 aagccatgga tttctttctc catgagttag ggactgacgg tcaggaagat gagtatacca
    57541 ttacttttaa tggtggatta gttcagaaaa atacaggaga aatccttgat aaaacagtct
    57601 tttcatatga tgatgtggca cgtttgtatg aagaaacaga gaaattatca ctgcctcttg
    57661 atgccatctc agaaggaaca gtttatcaaa tccaatcgga ccaagaaagt ctttatgcca
    57721 aattcaatcc agctttgact tttgttccag ttgactttga agacctgtct agtcaaatga
    57781 cctacaacaa atgcgtgacc gcctttgctc aagaaccctt ggatgcagcc attcagaaga
    57841 tttctctaga attgtttgac caatatgaaa tctttaaatc acgtgaaatg ttgctagaat
    57901 ggtcaccaaa gaatgttcat aaagcaacag gtttggcaaa actaatcagc catcttggaa
    57961 tcgaccaaag ccaagtgatg gcttgtggtg acgaggccaa cgacctctct atgattgaat
    58021 gggcaggtct tggtgttgct atgcaaaacg ctgttcctga agtaaaggta gccgcaaatg
    58081 tagtgacgcc gatgaccaac gatgaggaag ctgtcgcctg ggctatcgaa gaatatgtgc
    58141 taaaggagaa ctaagatatg ggattgtttg accgtttatt cggaaaaaaa gaagaaccta
    58201 aaatcgaaga agttgtaaaa gaagctctgg aaaatcttga tttgtctgaa gatgttgatc
    58261 ttaccttcac agaagctgat gaagttcctc aggaagaagc agaggttgaa attgttgaac
    58321 aagctgtgtt ccaagaagag gaaatccaag acacagttga agaaagtcag gattcagagc
    58381 cagctgtagg ggtttctcaa gaagaaatag aagaattacc aaactcagaa gaattaccag
    58441 aggaagagaa gcttgagcac gaaggaactg tagaagaaaa taattctgaa gtgcttgaac
    58501 cagaagctcc tcaaacagaa gaaactgttc aggaaaaata tgaccgcagt cttaagaaaa
    58561 ctcgcacagg tttcggtgcc cgcttgaatg ccttctttgc taacttccgc tctgttgacg
    58621 aagaattttt cgaggaactg gaagaactgc tgattatgag tgatgttggt gtccaagtcg
    58681 cttctaactt aacggaggaa ctacgttacg aagccaagct tgaaaatgcc aagaaacctg
    58741 atgtacttcg tcgtgtcatc attgagaaat tggttgagct ttatgaaaag gatggtagct
    58801 acgatgaaag catccacttc caagataact tgacagttat gctctttgtt ggtgtgaatg
    58861 gtgttgggaa aacaacttct atcggaaaac tagcccaccg ctacaaacaa gctggtaaga
    58921 aggtcatgct ggttgcagca gataccttcc gtgcgggtgc agtagctcag ctagctgaat
    58981 ggggccgacg agtagatgtt ccagtagtaa ctggacctga aaaagctgat ccagccagcg
    59041 tggtctttga tggtatggaa cgtgccgtgg ctgaaggtat cgatattctc atgattgata
    59101 ctgctggtcg tctgcaaaat aaggataacc ttatggctga gttggaaaag attggtcgta
    59161 ttatcaaacg tgttgtgcca gaagcaccac atgaaacctt cttggcactt gatgcatcaa
    59221 caggtcaaaa tgccctagta caggccaaag aattttcgaa aatcacacct ttaacgggaa
    59281 ttgttttgac taagattgat ggaactgctc gaggaggtgt ggttctagcc attcgtgaag
    59341 aactcaatat tcctgtaaaa ttgattggtt ttggtgaaaa aatcgatgat attggagagt
    59401 ttaactcaga aaactttatg aaaggtctct tggaaggctt aatctaatca gaagcaaaaa
    59461 tcctgcaagg tacaaacttg caggattttt ttattcgaaa cgaccatctt gacgataggc
    59521 gatatctggt tgccaagtcc atttggcacc gaatttttca agtaggtcaa agctggcttg
    59581 aggtcccatg cttccagctt tatagtcatg aagtggggca ccattttcag cccagagctt
    59641 ttcaatacgg tcaatcaact tccatgacgc acaaacttca tcccagtggc taaagttagt
    59701 tgagttgtta tttaggacat cataaatcaa tttttcgtat ggttctggag aagcaccagt
    59761 tgcagtcgca tctgtacggt aatcaagtga gttaggagcc aagttaaatt cttctcctac
    59821 ttgcttccca tttaggctaa gagagaagcc ttctgttggt tgaatataga tggtcaaaat
    59881 atttggagca agtggttctc caaagataga atccatttgt ttaaagacga tgttgacatg
    59941 agttcctttt tcagtcagtc gtttacctgt acggaaaaag aaaggaacac cacggaatcg
    60001 atcgctgtct acaaagaagg caccagatgt aaaggtttca gttgttgatt ctggattcac
    60061 atttggctcg ctacgataag agatgtattt catgccatca atcttaccag agcggtattg
    60121 cccacggata aagtgttctt tgagttcttc atcagttgga tgatagaggt ttttaaagac
    60181 cttaatcttt tcagcacgaa tctcgtcttt tgtgaagctt gctggtttgt ccatggcgag
    60241 gagcgaaaga agttgtagag tgtggttttg gaccatgtca cggagggcac cggattggtc
    60301 atagtagcca ccacgttctt ctacacccaa gcgctccgca aaggtaattt gaacattgtc
    60361 gataaaatcc ttgttccaaa cgttttcaaa aatcaagttt gcaaagcgaa ctgcaaagat
    60421 gctttggatc atttccttac caagataatg gtcgatacgg aaaatttgtt cttcgtcaaa
    60481 tgttgctagg agttcgacat tcaacttgct tgcagttgcg taatctgtac caaatggttt
    60541 ttcaacgatc aagcgctcaa aacctttgcc atcgacaatg ttttcagatt tgaggtgttt
    60601 ggcaatggtt ccaaagaact gaggtgccat agacaagaag aagagcttat tgtgttcagc
    60661 ttggtatttt tcattaagct cagcttgtaa ttgacgcaaa gcaatataat gttccgaatc
    60721 attgacatca tggctttgat agtagaagtg gctagcaaat tcttgggctt gctcggtact
    60781 atctgccaaa tcaaggatgg actcgacaac tacagattca aaatattcct tactccaagg
    60841 tctacgggca gttccaataa cggcaaagtg cttggaaaga ttgccggatt gatatagtct
    60901 aaaaagggaa gggtagagct tgcgtttagc caggtctcca ctcgcaccga aaattgtaac
    60961 aataacctta gatgacatct agctacctaa tttctatttt tattcctagt cttgctaggt
    61021 atgaggaaac ctcatttcat aaacttaatt ctaacataat tttccgaaaa atcaaaaatt
    61081 ccaatacgag gtagaaaaac tgcaaggaaa tccttacagt ttgagtttag acgtttaaga
    61141 ccttatctaa gaactctttc agacgagggt gttgtgggtt atcaaagatt tggtcaggtg
    61201 ttccgtcttc aaggaactcg ccatctgcag taaagataac gcggttggca acctgacgag
    61261 caaatcccat ctcatgggtt acgataatca tggtcatgcc ttgctcagcc aattccttca
    61321 taacgttaag tacgtctcca accatctcag ggtcaagggc agaagttggt tcatcgaaga
    61381 gcatgatgtc tggattcatt gctaggccac gagcgatggc cacacgttgt ttttgaccac
    61441 ctgataggct atctggattg gcattagctt tatctgctag tccaaccttt tcaagcaact
    61501 ccattcccaa ttcctcagct tcttccttag tcatcaactt gtgctcaata ggagcaaagg
    61561 tgatgttgtc caatacagac atatgaggga agaggttgaa gtgttggaat accatgccga
    61621 tattttcacg gacgtggtca acattggttg ttttttcagt taaatcatag ccgttcacag
    61681 tgatgtgacc gctagtgact tcttctaaaa gattgaggct acggaggaaa gttgacttac
    61741 cagaacctga aggaccgatg atacaaacaa catctccttc atagaactta gtcgtaattc
    61801 cttttaggac ttcatttttt ccatagtact tgtgtaaatc atttacatca atttttaatt
    61861 ttgccattaa cgaatcctct tttctaagcg tttcgctagt ctagtcaaaa gtgtgataat
    61921 tacaagatag aagatagcaa ggattgcata catcttgaaa ctttggtagt tacgagcaat
    61981 gataatctta ccagtttgga agagttcaac caaaccgata gcagatacga tagttgtatc
    62041 tttaagagcg ataacgaatt ggttgacaaa gtttggcaac atcaatttag ttgcttgtgg
    62101 caagataatc ttacgcatgg tttttccata agagataccc aagcttcggc tggcttccat
    62161 ttggccaact ggaacggcct gaataccacc acgaacgatt tcagcgatat aagcagccgc
    62221 attgagtgag agggcaattg ttccagctac aaagtcgtta attgggcttt gttggcctgt
    62281 gatagactcg atgaagtttg gaattcccca gaagatgaag gctgcaagaa tcatcaatgg
    62341 aataccacga ataacgtcaa cgaaaatctc agagatgacg cgaagagatt tgtatgggct
    62401 aacgctaaac ataccgaaga taattccgat gacaatggca atagcaaatg agataagagc
    62461 tagagcaaga gtgataccaa gaccgctaag gagttgtttg tagttgtttt gaagcaagcc
    62521 ccagagcgtt gtttcgtcaa cagtacttgt tgaagcagtt gaagattcgc tagctaggta
    62581 tttgtcaaga atcttttgga attcaccgtt tgctttaagg tttgcaagtc cgttgttgaa
    62641 catttcaatc agttctggat ttgctccttt tttaacggca aaggctgttt caccgattgg
    62701 agttccagag attggagttt tcaatttttg accttggctg atagaatatt tgagaacagg
    62761 ttcatcatcc ataacggcat caatggcacc agtgtttaaa ctgtcataca ttgaagaacc
    62821 atcagcaaag gttttgattt tgtaaccgta tttgctttga ttttctgtta ggaaggtttg
    62881 agaagcagtt ccgtttttaa caccgactgt ctttcctttt agatcttcat aagaagcaat
    62941 attgcttgat tctttgacac caagaatggt attagcagtg tagtatgatt ctgagaagtc
    63001 aaaagttgcc ttacgagcat ctgtgacaga cataccagca atgataccat cggcttgacc
    63061 agcttggaca gcactgatag cagcatcaaa accagggttg gtgatttcaa tttcaaaacc
    63121 ttggtcttta gcgattgcct taatcaattc catatcaata ccagtgtatt ggttgcttga
    63181 attttggaaa acaaaaggtg caaaagaaga atcgctggca atgatatatt tagccttaac
    63241 aggaatagct tttaatcctg cgagagtagt tgtagttggc actgctgaag atgatgaagc
    63301 agtccatttc ttgataattt tatcaagact accatctttt ttcatttcag acaaggcttg
    63361 gttaaattca gtaaccaggt gctcgtattt acttcctttt ttcacaccga aagcaaaact
    63421 tcctacagct tcaccatcca tttcaatatg gaggtcttga ccttggttaa tggcatattc
    63481 gataacaggt ttgtcatcca tcatggcatc gatggcacca gcactcaagc tgttgttcat
    63541 taaatcacca gtgtcaaatg ttttaatagt aaagccgtat ttatctttga ttgtttcaag
    63601 gaaacgttga gcggcagttc cgtttttaac accaacggtt ttgccagtta attggtcgta
    63661 cttgctaatt ttgtgtgact ttgtagtagc aatgacaact tttgtatcat agtaagtatc
    63721 agacatggtg aagacttttt cacgttcttt agtctttgtc atccctgcca tgatagcgtc
    63781 ggcttgccca gcttgaaccg cattgactgc tgcgtcaaat ccaggatagg acatctgaat
    63841 gttccagcct ttaatctcag cgactttgtt aataatgtca acatcaattc ctttataagt
    63901 ttgatctgaa tctttaaact caaaaggtgc ataggcggta tcagaaacaa tcttaatcgt
    63961 ttctgctttg gcaataccta atgagaaaat tgggaataaa attagcaaaa atgctagaaa
    64021 ttttttcttc atttttagtc tccttttccg aatattctct cattatatca gaaaaagtaa
    64081 aaaaaggcaa atttttatat ttttcgtgtc agaaaatata acattgattt ttccttttct
    64141 ttcttgaatt gctattaaaa agtgctataa taatagtata tatagaagaa aagaggacgg
    64201 ggatatgaag aacaaaagaa tatttaaaga cttccaagct tcaaaaatga gtttaaacat
    64261 ttacacaagc cccttgttag cctttgtttt tgtcttcata ggagagtttg tggcttttac
    64321 tttgtatggt attggcttgt tagctctcat cggacttgct agaaattttg gagaggctgg
    64381 tcaaaatctt gcaacctact tgcagacctt gcatcagagc ttgacggata aaacaagtga
    64441 ctttcgttta attttaggat tactggcctt tggttttatt cttaacactg tgttcagatg
    64501 gacaagaaaa gttgagaaaa gacctattcg aaccttggga ttttatagag agaatttcct
    64561 cagcaatctt ctgaaaggat ttagtctagg cttggcactt tttcttctga ccttgttagg
    64621 tttagtggtc ttaggtcaat atcgtttgga atccattcac ttgaatcctt attctcttgc
    64681 ctttgtcgtc tttactatcc cattttggat tttacagggg acagcagaag aagtggtggc
    64741 ccgtgcttgg ctacttcctc aattggcctc aagaaccaat ctaaaactag ctattcttat
    64801 atctagcctg ttctttaccc tgcttcatat gggcaattct ggcctcaccc ctctatctct
    64861 agtaaatctc tttttattcg gagttgccat ggctctttat cttctcaaaa ctgatacagt
    64921 ttggggtgtt gcaggtattc atggtgcttg gaattttgct cagggtaatc tctttgggat
    64981 tttagttagt ggtcaaccgt caggaacgtc tctgatgacc tttttaccac aaggcaatca
    65041 agattggcta tcaggtggtt cttttggcat agaaggttcc attatgacaa gtctggtatt
    65101 actactgctg attgtctatc ttgctaataa attaaagaaa gaaaatgaaa ggatgtgact
    65161 tcggtccgtc cttttcttcg tgaaaatact ataagtatgc taaaatagga atagcacatg
    65221 gagagaggat tcttatgatc aatcacatta cagataatca atttaaacta gtatcaaaat
    65281 atcaaccatc aggagatcaa ccccaagcta tcgagcagtt ggtggataac attgaggggg
    65341 gagaaaaagc tcagattctg atgggggcga ctggaacagg gaagacctat actatgagtc
    65401 aggtcatttc taaagtcaat aaaccaactc tggttattgc ccacaataaa actctggctg
    65461 gtcagctcta tggggagttt aaggaatttt tccctgaaaa tgcagttgag tatttcgtat
    65521 cctactatga ttattaccag ccagaggcct atgtcccttc tagcgatacc tatattgaga
    65581 aggatagttc tgtcaatgac gagattgaca agcttcgcca ctcagctacc tcagcccttt
    65641 tggagcgtaa tgatgttatt gtcgtggcct cagtctcttg tatctatggt ttgggttcgc
    65701 ccaaggaata cgctgatagt gtcgttagtc tccgtcctgg tctagagatt tctcgtgata
    65761 aactcttgaa tgacttggtc gatattcagt ttgaacgtaa tgatattgat ttccaacgcg
    65821 gaagatttcg cgttcgtggg gatgtggtag agattttccc agcttcccga gatgaacatg
    65881 cctttcgagt agaatttttt ggagacgaaa ttgaccgtat ccgtgaggtt gaggctctga
    65941 caggtcaggt attgggagag gtggatcatt tggcgatttt cccagctact cactttgtga
    66001 ccaatgacga ccatatggaa gttgccgttg ccaagattca agcagaatta gaagagcagt
    66061 tagctgtctt tgaaaaggaa ggtaaactgc ttgaagccca gcgtttgaaa cagcggacag
    66121 agtatgatat cgaaatgttg cgtgagatgg gctataccaa tggggttgaa aattattctc
    66181 gccacatgga tggacggagc gaaggagagc ctccttatac gcttctcgac ttcttcccag
    66241 atgatttctt gattatgatt gacgagagtc atatgaccat agggcaaatc aagggcatgt
    66301 acaatggaga ccgttcgcgt aaggaaatgc tagtaaatta tggtttccgt ttaccgtctg
    66361 ccttggacaa tcgtcctctc cgtcgtgagg agtttgaaag ccatgtgcat cagattgttt
    66421 acgtatcagc gacacctggt gactatgaaa atgaacagac tgagacggtg attgagcaaa
    66481 tcattcgacc gacagggctt ttggatcctg aggtggaagt ccgtccgact atgggacaga
    66541 ttgatgatct cttaggtgaa atcaatgccc gtgttgaaaa gaatgaacga acctttatca
    66601 ccaccttgac caagaaaatg gcagaggact tgaccgacta tttcaaggaa atgggcatca
    66661 aggtcaagta catgcactcg gatatcaaga ccttggaacg gacggagatt atccgtgatc
    66721 tccgcttggg tgtctttgat gtcttggttg gaatcaatct ccttcgtgaa gggattgacg
    66781 ttcctgaggt tagcttggtt gccattctcg atgctgacaa ggaaggtttc cttcgtaacg
    66841 agcgtggact catccagacc attgggcgtg ccgcccgtaa cagtgaaggt catgtcatca
    66901 tgtatgcaga tacggttacc cagtctatgc aacgtgctat cgatgaaact gcccgccgtc
    66961 ggaaaattca gatggcctat aatgaagagc atggtatcgt accacagaca atcaagaaag
    67021 aaatccgtga cctgattgcc gtgaccaagg cagttgctaa ggaagaggac aaggaagtcg
    67081 acatcaatag cctcaacaaa caagagcgca aagaactcgt caagaaacta gaaaaacaaa
    67141 tgcaagaagc cgtcgaagtg cttgactttg aactggcggc tcagatccgt gatatgatgt
    67201 tggaagtcaa ggccttggat taggggaata gtatgattta tttaagaaag ttaaagaaag
    67261 aagatttgat gtctttatgg gaaatggctt attcacagct taatccagtt tggaaacagt
    67321 atgatgctcc ctattatgat gattatcagt atttttcaaa ttttaaagaa ttcgaactac
    67381 aaaaatcaga atccatttta agcaactcaa atcgccttgg tatttttgtt gatgataaac
    67441 tagttgggac tgtttcgcgt tattgggtat gtaaagaaac aagatggatg gaattgggaa
    67501 ttggtattta tgataaaaaa ttctggaaca ctggtattgg gaaagttgct atgttgcagt
    67561 ggatagatag gacgtttcag gattacttgg agttggagca tctgggtttg acaacttggt
    67621 cagggaatct tggtatgatg aaacttgctg aaaaattaag aatgaaaaaa gaagctcata
    67681 ttccaaaagt tcgttattat caaggtaaat attttgatag tattaaatat ggtattttga
    67741 gagaagactg ggagaaaata aatgacggtt attatcaaat caatggaaac tcctgaagag
    67801 atagaaggta aatccctcgt tcactggcaa acgtggagag aggcttatga tgaccttttg
    67861 cctgcagaat ttcaggagac aatgacatta gaaagatgtc gattctttag tcaaaagtat
    67921 ccagaaaata cattgattgc gataggtgat ctgaaggtag ttggttttat cagttatggt
    67981 aactttcgtg atgatactat tcaagctggt ggaattattg ctttatatgt tttaaaagac
    68041 tattacggaa aaggcatagc acaaaagtta atgaaagcag ctttgactgc tcttaatcat
    68101 ttttctgaaa ttttcttatg ggtattgaaa gataacaagc gcgccattgc tttctatcaa
    68161 aaaatgggtt ttacttttga tggacaagaa aaaatacttg aacttggaaa gcctataaag
    68221 gaaaaacgaa tggtgttcta ttctaaataa ttttaaaaaa gtaaaagata atatctctgg
    68281 tagtaagtct gaaaatttaa taaattagaa agcgagtaaa tttatgtccc gttcccaatt
    68341 aacaatttta acaaatatct gtctgattga agacctcgaa acgcagcgcg tggtgatgca
    68401 gtatcgcgcc cctgaaaaca atcgctggtc tggttatgcc tttcctggag gtcatgtaga
    68461 aaatgatgag gcttttgcgg agtctgtcat tcgtgaaatc tacgaagaaa cagggttgac
    68521 tatccaaaat cctcaacttg tcggcattaa aaattggcca ctagatacag gtgggcgcta
    68581 tattgtcatt tgttataagg cgactgagtt ctctggtacc cttcaatctt cagaagaggg
    68641 agaagtttct tgggtgcaaa aagaccagat tccaaactta aatctggcct atgatatgct
    68701 accattgatg gaaatgatgg aagctcccga caagtcagag tttttctacc ctcgccgtac
    68761 agaagacgat tgggaaaaga aaatcttcta gtcttttact aaataaccta gctgatccaa
    68821 ggcctcctcg atatagtgga ggtcttgttg tgtttcggct tcgactaggt ggtaatggat
    68881 gccatctgtc aattcagata gaggtctaaa gtcagaatgc tcgacttgtt ctagaaaatg
    68941 ttgcacatct ctgcgacaag acagtttaag caaggtttca atttctccat aaacgggatg
    69001 gtcaatcaag gtattctgga catgcccacc attatcgaca atagcaagga gttcctgacc
    69061 gatttcttca acttcatgtt tcactttgaa aagtttgtga acataaggat tggtatcaat
    69121 ttgcttatag atgtagccac gattggtgga taggatagga gcgccatcgg ctctcaaaat
    69181 tgcaatgtcc tgcacaatga cctgacgtgt gacatgaaaa tgttccgcca aactttggcc
    69241 attaagggct ttaggagctt ctttcaagag ttggagcagg gcttgtttgc gatcttttgt
    69301 catagctttt ccttttaacg gcgttttcga agcactttat agacagctag tgctaatgta
    69361 tagtctacca tactatggat aattgtgcca aatccaacta gtacaaatag aacatagaac
    69421 atgttttcta cattggtacc cgaagttgcg taaaaaagga cacaggctaa tacttcagca
    69481 agggcatgaa caacagccaa aacaaaattg aaaacccagg aagattttgg tttatctagg
    69541 gtatcgggga atttttgtag gtaaagagct cctaaagcac caaaagatat atgggaaaaa
    69601 gcccgaaaaa cgataaccat gggatagcca gccatcaaaa atccaaaact agaggctagg
    69661 atgacaaaaa ctgccatcaa gggcgacaag aacatggcta taaaaatagc gatgtggctc
    69721 cccaaagtat aggaagcagg tggaatgaca atcttgaaag gcataacaat tggaatcaaa
    69781 atcgcaatag ccgttaaaag ggctgtcatt gtcataaatt gtgtcttttt ccgtgtattc
    69841 acaagaatct cctttttaac tgcatataca ctagtatggt acaataaacc agacaataaa
    69901 gcaagaattt acttgggttt atagatcatt ttttagttaa aagttatagt agattgaaac
    69961 t
//
LOCUS       DAVBOG010000003        68088 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.003, whole genome shotgun sequence.
ACCESSION   DAVBOG010000003 DAVBOG010000000
VERSION     DAVBOG010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 68088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68088
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.003"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ865_000154"
     CDS             <1..116
                     /locus_tag="VQ865_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3134582.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVASLK"
     gene            135..1652
                     /locus_tag="VQ865_000155"
     CDS             135..1652
                     /locus_tag="VQ865_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000477452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3134583.1"
                     /translation="MFKVLQKVGKAFMLPIAILPAAGLLLGIGGALSNPTTIATYPIL
                     DNSIFQSIFQVMSSAGEVVFSNLSLLLCVGLCIGLAKRDKGTAALAGVTGYLVMTATI
                     KALVKLFMAEGSAIDTGVIGALVVGIVAVYLHNRYNNIQLPSALGFFGGSRFVPIVTS
                     FSSILIGFVFFVIWPPFQQLLVSTGGYISQAGPIGTFLYGFLMRLSGAVGLHHIIYPM
                     FWYTELGGVETVAGQTVVGAQKIFFAQLADPAHSGLFTEGTRFFAGRFSTMMFGLPAA
                     CLAMYHSVPKNRRKKYAGLFFGVALTSFITGITEPIEFMFLFVSPVLYVVHAFLDGVS
                     FFIADVLNISIGNTFSGGVIDFTLFGILQGNAKTNWVLQIPIGLIWSVLYYIIFRWFI
                     TQFNVLTPGRGEEVDSKEISESADSTSNTADYLKQDSLQIIRALGGSNNIEDVDACVT
                     RLRVAVKEVNQVDKALLKQIGAVDVLEVKGGIQAIYGAKAILYKNSINEILGVDD"
     gene            1777..3105
                     /locus_tag="VQ865_000156"
     CDS             1777..3105
                     /locus_tag="VQ865_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3134584.1"
                     /translation="MKFRKLACTVLAGAAVLGLAACGNSGGSKDAAKSGGDGAKTEIT
                     WWAFPVFTQEKTGDGVGTYEKSIIEAFEKANPDIKVKLETIDFKSGPEKITTAIEAGT
                     APDVLFDAPGRIIQYGKNGKLAELNDLFTDEFVKDVNNENIVQASKAGDKAYMYPISS
                     APFYMAMNKKMLEDAGVANLVKEGWTTDDFEKVLKALKDKGYTPGSLFSSGQGGDQGT
                     RAFISNLYSGSVTDEKVSKYTTDDPKFVKGLEKATSWIKDNLINNGSQFDGGADIQNF
                     ANGQTSYTILWAPAQNGIQAKLLEASKVEVVEVPFPSDEGKPALEYLVNGFAVFNNKD
                     DKKVAASKKFIQFIADDKEWGPKDVVRTGAFPVRTSFGKLYEDKRMETISGWTQYYSP
                     YYNTIDGFAEMRTLWFPMLQSVSNGDEKPADALKAFTEKANETIKKAMKQ"
     gene            3358..4224
                     /locus_tag="VQ865_000157"
     CDS             3358..4224
                     /locus_tag="VQ865_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3134585.1"
                     /translation="MRETVISYAFLAPVLFFFVIFVLAPMVMGFITSFFNYSMTKFEF
                     VGLDNYIRMFKDPVFTKSLINTVILVIGSVPVVVLFSLFVASQTYHQNVIARSFYRFV
                     FFLPVVTGSVAVTVVWKWIYDPLSGILNFVLKSSHIISQNISWLGDKNWALMAIMIIL
                     LTTSVGQPIILYIAAMGNIDNSLVEAARVDGATEFQVFWKIKWPSLLPTTLYIAIITT
                     INSFQCFALIQLLTSGGPNYSTSTLMYYLYEKAFQLTEYGYANTIGVFLAVMIAIVSF
                     VQFKVLGNDVEY"
     gene            4240..5079
                     /locus_tag="VQ865_000158"
     CDS             4240..5079
                     /locus_tag="VQ865_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3134586.1"
                     /translation="MQSTEKKPLTAFTVISTIILLLLTVLFIFPFYWILTGAFKSQPD
                     TIVIPPQWFPKMPTMENFQQLMVQNPALQWMWNSVFISLVTMFLVCATSSLAGYVLAK
                     KRFYGQRILFAIFIAAMALPKQVVLVPLVRIVNFMGIHDTLWAVILPLIGWPFGVFLM
                     KQFSENIPTELLESAKIDGCGEIRTFWSVAFPIVKPGFAALAIFTFINTWNDYFMQLV
                     MLTSRNNLTISLGVATMQAEMATNYGLIMAGAALAAVPIVTVFLVFQKSFTQGITMGA
                     VKG"
     gene            5351..5803
                     /locus_tag="VQ865_000159"
     CDS             5351..5803
                     /locus_tag="VQ865_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3134587.1"
                     /translation="MIFDDLKNITFYKGIHPNLDKAIDYLYQHRKDSFELGKYEIDGD
                     KVFLVVQENVLNQVENNQFEHHKNYADLHLLVEGHEYSSYGSRIKDEAVAFDEATDIG
                     FVHCHEHYPLLLGYHNFAIFFPGEPHQPTGYAGMEEKVRKYLFKILID"
     gene            5900..6244
                     /locus_tag="VQ865_000160"
     CDS             5900..6244
                     /locus_tag="VQ865_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134588.1"
                     /translation="MVSSKHAARASFLDGQGITVDEMSWIINGIVNALIGRYIKLGTY
                     AAKYGISIARSILSRAAATAAARVGLLTKISGWILRVAVNVADVYGNFANNIAAAWDA
                     YDKIPNNGRINF"
     gene            6528..7172
                     /locus_tag="VQ865_000161"
     CDS             6528..7172
                     /locus_tag="VQ865_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3134589.1"
                     /translation="MAQKGVSLIKAAFDTDNFLMRFSEKVLDIVTANLLFVVSCLPIV
                     TIGVAKISLYETMFEVKKSRRVPVFKIYLRSFKQNLKLGLQLGLLELGIVSLSLLDLY
                     LFWGQTALPFQLLKAICLGILIFLTIVMLASYPIAARYDLTWKEILQKGLMLASFNFP
                     WFFLMLAILVLIVMVLYLSAFSLLLGGSVFLLFGFGLLVFIQTGLMEKIFAKYQ"
     gene            7341..8258
                     /locus_tag="VQ865_000162"
     CDS             7341..8258
                     /locus_tag="VQ865_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3134590.1"
                     /translation="MSDLKKYEGVIPAFYACYDEQGEVSPERTRALVQYFIDKGVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGAKAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEGLNIGSVR
                     SPLTPVTEEDRPVVEAAAALIRETKERFL"
     gene            8276..9160
                     /locus_tag="VQ865_000163"
     CDS             8276..9160
                     /locus_tag="VQ865_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3134591.1"
                     /translation="MTYYVAIDIGGTNIKYGLVDQEGQLLESHEMPTEAHKGGPHILQ
                     KTKDIVASYLEKGPVAGVAISSAGMVDPDKGEIFYAGPQIPNYAGTQFKKEIEESFTI
                     PCEIENDVNCAGLAEAVSGSGKGASVTLCLTIGTGIGGCLIMDRKVFHGFSNSACEVG
                     YMHMQDGAFQDLASTTALVKYVAEAHGEDVDQWNGRRIFKEATEGNKICMEGIDRMVD
                     YLGKGLANICYVANPEVVILGGGIMGQEAILKPKIRTALKEALVPSLAEKTRLEFAHH
                     QNTAGMLGAYYHFKTKQS"
     gene            complement(9176..10027)
                     /locus_tag="VQ865_000164"
     CDS             complement(9176..10027)
                     /locus_tag="VQ865_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HET3134592.1"
                     /translation="MDKPDIATIIDSHFEEMTDLEQEIARYFLQAETITDDLSSQQVT
                     QKLHISQAALTRFAKKCGFTGYREFIFQYQHQAENQANQVSKHSPLTKRVLRSYSNMR
                     EQTQDLIDEIQLERIAQLIEDAERIYFFGTGSSGLVAREMKLRFMRLGVVCEALTDQD
                     GFAWTTSIMDENCLVLGFSLSGSTPSILDSLIDAKEMGAKTVLFTSVPNKDSQTYTET
                     VLVATHSQPSYIQRISAQLPMLFFIDLIYAYFLEINRESKEKIFNSYWENKKLNGYRR
                     QKRVRKS"
     gene            10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ865_000165"
     CDS             10227..12284
                     /gene="pbp2b"
                     /locus_tag="VQ865_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2B"
                     /protein_id="HET3134593.1"
                     /translation="MRLICMRKFNSHSIPIRLNLLFSIVILLFMTIIGRLLYMQVLNK
                     DFYEKKLASASQTKITSSSARGEIYDASGKPLVENTLKQVVSFTRSNKMTATDLKETA
                     KKLLTYVSISSPNLTERQLADYYLADPEIYKKTVEALPSEKRLDSDGNRLSESELYNN
                     AVDSVQTSQLNYTEDEKKEIYLFSQLNAVGNFATGTIATDPLNDSQVAVIASISKEMP
                     GISISTSWDRKVLETSLSSIVGSVSSEKAGLPAEEAEAYLKKGYSLNDRVGTSYLEKQ
                     YEETLQGKRSVKEIHLDKYGNMESVDTIEEGSKGNNIKLTIDLAFQDSVDALLKSYFN
                     SELENGGAKYSEGVYAVALNPKTGAVLSMSGIKHDLKTGELTPDSLGTVTNVFVPGSV
                     VKAATISSGWENGVLSGNQTLTDQSIVFQGSAPINSWYTQAYGSFPITAVQALEYSSN
                     TYMVQTALGLMGQTYQPNMFVGTSNLESAMEKLRSTFGEYGLGTATGIDLPDESTGFV
                     PKEYSFANYITNAFGQFDNYTPMQLAQYVATIANNGVRVAPRIVEGIYGNNDKGGLGN
                     LIQQLQPTEMNKVNISDSDMSILHQGFYQVAHGTSGLTTGRAFSNGALVSISGKTGTA
                     ESYVADGQQATNTNAVAYAPSDNPQIAVAVVFPHNTNLTNGVGPSIARDIINLYQKYH
                     PMN"
     gene            12295..12891
                     /gene="recR"
                     /locus_tag="VQ865_000166"
     CDS             12295..12891
                     /gene="recR"
                     /locus_tag="VQ865_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HET3134594.1"
                     /translation="MLYPTPIAKLIDSYSKLPGIGIKTATRLAFYTIGMSADDVNEFA
                     KNLLSAKRELTYCSICGRLTDDDPCSICTDPTRDQTTILVLEDSRDVAAMENIQEYHG
                     LYHVLHGLISPMNGISPDDINLKSLMTRLMDSEVSEVIVATNATADGEATSMYLSRLL
                     KPAGIKVTRLARGLAVGADIEYADEVTLLRAIENRTEL"
     gene            13086..14129
                     /locus_tag="VQ865_000167"
     CDS             13086..14129
                     /locus_tag="VQ865_000167"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HET3134595.1"
                     /translation="MKQTIILLYGGRSAEREVSVLSAESVMRAVNYDRFTVKTFFISQ
                     SGDFIKTQEFSHAPGQEDRLMTNETIDWDKKVAPSAIYEEGAVVFPVLHGPMGEDGSV
                     QGFLEVLKMPYVGCNILSSSLAMDKITTKRVLESAGIAQVPYVAIVEGDDVTAKIAEV
                     EEKLAYPVFAKPSNMGSSVGISKSENQEELRQALKLAFRYDSRVLVEQGVNAREIEVG
                     LLGNYDVKSTLPGEVVKDVAFYDYDAKYIDNKITMDIPAKISDDVVAVMRQNAETAFR
                     AIGGLGLSRCDFFYTDKGEIFLNELNTMPGFTQWSMYPLLWDNMGISYPELIERLVDL
                     AKESFDKREAHLI"
     gene            14213..15586
                     /locus_tag="VQ865_000168"
     CDS             14213..15586
                     /locus_tag="VQ865_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HET3134596.1"
                     /translation="MKLTIYEVAQAVGAKNDVSLFADAQLEKAEFDSRLIGTGDLFVP
                     LKGALDGHDFIETAFENGAAVTLSEKEVSNHPYILVDDVLTAFQSLASYYLEKTTVDV
                     FAVTGSNGKTTTKDMLAHLLSTRYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMG
                     QDHLGDIHLLSELARPKTAIVTLVGEAHLAFFKDRSEIAKGKMQIADGMASGSLLLTP
                     ADPIVEDYLPTDKKVVRFGQGAELEITDLVERKDSLTFKANFLEQALDLPVTGKYNAT
                     NAMIASYVALQEGVSEEQIHQAFQGLELTRNRTEWKKAANGADILSDVYNANPTAMKL
                     ILETFSAIPANEGGKKIAVLADMKELGDQSIQLHNQIILSLSPDVLDTVIFYGEDIAE
                     LAQLASQMFPIGHVYYFKKTEDQDQFEDLVKQVKESLGAHDQILLKGSNSMNLAKLVE
                     SLENEDK"
     gene            15573..16184
                     /locus_tag="VQ865_000169"
     CDS             15573..16184
                     /locus_tag="VQ865_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3134597.1"
                     /translation="MKTSDFVKYLQRMIAITDTGLTFTKDPFDRERYEDLRDFLSEML
                     NQASDLDSEEVAEVLKPTSAYATPLMDVRAWIVEDEKICLVRGQGEDSWALPGGFGEV
                     GYSPTENILKEIEEETGFKAKVERLLAVFDTNRFQLQSKQYTKFVFGCKLLDGQFQEN
                     QEIADLQFFAIDQLPNLSEKRITKEQIELLWQVYQGHRGQYLD"
     gene            16275..16979
                     /locus_tag="VQ865_000170"
     CDS             16275..16979
                     /locus_tag="VQ865_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001055242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR02206 family membrane protein"
                     /protein_id="HET3134598.1"
                     /translation="MNLWDIFFTTQATEPPKFDLFWYVSLFTLLALTFYTAHRYREKK
                     VYQRFFQILQTVQLILLYGWYWVNHMPLSESLPFYHCRMAMFVVLLLPGQSKYKQYFA
                     LLGTFGTLAAFVYPVPDAYPFPHITILSFIFGHLALLGNSLVYLLRQYNARLLDVKGI
                     FLMTFALNALIFVVNLVTGGDYGFLTKPPLVGDHGLVANYLLVSIVLVATISLTKKIL
                     EFFLAQEAEKMIAKEA"
     gene            17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ865_000171"
     CDS             17198..18571
                     /gene="ftsA"
                     /locus_tag="VQ865_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HET3134599.1"
                     /translation="MAREGFFTGLDIGTSSVKVLVAEQRNGELNVIGVSNAKSKGVKD
                     GIIVDIDAAATAIKSAISQAEEKAGISIKSVNVGLPGNLLQVEPTQGMIPVTSDTKEI
                     TDQDVENVVKSALTKSMTPDREVITFIPEEFIVDGFQGIRDPRGMMGVRLEMRGLLYT
                     GPRTILHNLRKTVERAGVQVENVIISPLAMVQSVLNEGEREFGATVIDMGAGQTTVAT
                     IRNQELQFTHILQEGGDYVTKDISKVLKTSRKLAEGLKLNYGEAYPPLASKETFQVEV
                     IGEVEAVEVTEAYLSEIISARIKHILEQIKQELDRRRLLDLPGGIVLIGGNAILPGMV
                     ELAQEVFGVRVKLYVPNQVGIRNPAFAHVISLSEFAGQLTEVNLLAQGAIKGENDLSH
                     QPISFGGMLQKTAQFVQSTPVQPAPAPEVEPVAPTEPMADFQQASQNKPKLADRFRGL
                     IGSMFDE"
     gene            18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ865_000172"
     CDS             18588..19847
                     /gene="ftsZ"
                     /locus_tag="VQ865_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000144288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HET3134600.1"
                     /translation="MTFSFDTAAAQGAVIKVIGVGGGGGNAINRMVDEGVTGVEFIAA
                     NTDVQALSSTKAETVIQLGPKLTRGLGAGGQPEVGRKAAEESEETLTEAISGADMVFI
                     TAGMGGGSGTGAAPVIARIAKDLGALTVGVVTRPFGFEGSKRGQFAVEGINQLREHVD
                     TLLIISNNNLLEIVDKKTPLLEALSEADNVLRQGVQGITDLITNPGLINLDFADVKTV
                     MANKGNALMGIGIGSGEERVVEAARKAIYSPLLETTIDGAEDVIVNVTGGLDLTLIEA
                     EEASQIVNQAAGQGVNIWLGTSIDESMRDEIRVTVVATGVRQDRVEKVVAPQARSATN
                     YRETVKPAHSHGFDRHFDMAETVELPKQNPRRLEPTQASAFGDWDLRRESIVRTTDSV
                     VSPVERFEAPISQDEDELDTPPFFKNR"
     gene            19852..20523
                     /locus_tag="VQ865_000173"
     CDS             19852..20523
                     /locus_tag="VQ865_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HET3134601.1"
                     /translation="MNVKENTELVFREVGEASLSAHRESSSVSVIAVTKYVDVPTAEA
                     LLPLGVHHIGENRVDKFLEKYEALKDRDVTWHLIGTLQRRKVKDVIQYVDYFHALDSV
                     KLAGEIQKRSDRVIKCFLQVNISKEESKHGFSREELLEILPELARLDKIEYVGLMTMA
                     PFEASSEQLKEIFKATQDLQREIQEKQIPNMPMTELSMGMSRDYKEAIQFGSTFVRIG
                     TSFFK"
     gene            20533..21072
                     /locus_tag="VQ865_000174"
     CDS             20533..21072
                     /locus_tag="VQ865_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HET3134602.1"
                     /translation="MSLKDRFDRFIDYFTEDEDSSLPYEKRDEPVFTPVNSSQEPALP
                     MNQPSQSVGTKENNITRLHARQQELANQSQRATDKVIIDVRYPRKYEDATEIVDLLAG
                     NESILIDFQYMTEVQARRCLDYLDGACHVLAGNLKKVASTMYLLTPVNVIVNVEDIRL
                     PDEDQQGEFGFDMKRNRVR"
     gene            21072..21335
                     /locus_tag="VQ865_000175"
     CDS             21072..21335
                     /locus_tag="VQ865_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HET3134603.1"
                     /translation="MIFLIRMIYNAVDIYSLILVAFAVMSWFPGAYESSLGRWIVALV
                     KPVLAPLQRLPLQIAGLDLSVWVAIVLVRFLGENLVRFLAMIG"
     gene            21332..22117
                     /locus_tag="VQ865_000176"
     CDS             21332..22117
                     /locus_tag="VQ865_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HET3134604.1"
                     /translation="MNKGIYQHFSIEDRPFLDKGMEWIKKVEDSYAPFLTPFINPHQE
                     KLLKILAKTYGLACSSSGEFVSSEYVRVLLYPDYFQPEFSDFEISLQEIVYSNKFEHL
                     THAKILGTVINQLGIERKLFGDILVDEERAQIMINQQFLLLFQDGLKKIGRIPVSLEE
                     RPFTEKIDKLEQYRELNLSVSSFRLDVLLSNVLKLSRNQANQLIEKKLVQVNYHVVDK
                     SDYTVQVGDLISVRKFGRLRLFQDKGQTKKEKKKITVQLLLSK"
     gene            22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ865_000177"
     CDS             22126..22914
                     /gene="divIVA"
                     /locus_tag="VQ865_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIVA"
                     /protein_id="HET3134605.1"
                     /translation="MPITSLEIKDKTFGTRFRGFDPEEVDEFLDIVVRDYEDLVRANH
                     DKNLRIKSLEERLSYFDEIKDSLSQSVLIAQDTAERVKQAAHERSNNIIHQAEQDAQR
                     LLEEAKYKANEILRQATDNAKKVAVETEELKNKSRVFHQRLKSTIESQLAIVESSDWE
                     DILRPTATYLQTSDEAFKEVVSEVLGEPIPAPIEEEPIDMTRQFSQAEMEELQARIEV
                     ADKELSEFEAQIKQEVETPTPVVSPQVEEEPLLIQLAQCMKNQK"
     gene            23262..26054
                     /locus_tag="VQ865_000178"
     CDS             23262..26054
                     /locus_tag="VQ865_000178"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HET3134606.1"
                     /translation="MKLKDTLNLGKTAFPMRAGLPTKEPVWQKEWEDAKLYQRRQELN
                     EGKPHFVLHDGPPYANGNIHVGHAMNHISKDIIIRSKSMSGFNAPYIPGWDTHGLPIE
                     QVLAKQGVKRKEMDLVEYLKLCREYALSQVYKQRDDFKRLGMSGDWENLYVTLTPDYE
                     AAQIRVFGEMANKGYIYRGAKPVYWSWSSESALAEAEIEYHDLVSTSLYYANKVKDGK
                     GILDTDTYIVVWTTTPFTITASRGLTVGADIDYVLVQPASETRKFVVAAELLTSLSEK
                     FGWADVQVLATYRGQELNHIVTEHPWDTAVDELVILGDHVTTDSGTGIVHTAPGFGED
                     DYNVGIANGLEVAVTVDERGIMMANAGPEFEGQFYDKVVPTVIEKLGNLLLAQEEISH
                     SYPFDWRTKKPIIWRAVPQWFASVSKFRQEILDAIDKVKFHTEWGKVRLYNMIRDRGD
                     WVISRQRAWGVPLPIFYAEDGTAIMTAETIEHVAQLFEVHGSSIWWERDAKNLLPEGF
                     THPGSPNGEFKKETDIMDVWFDSGSSWNGVLVNRPNLTYPADLYLEGSDQYRGWFNSS
                     LITSVANHGVAPYKQILSQGFTLDGKGEKMSKSLGNTIAPSDVEKQFGAEILRLWVTS
                     VDSSNDVRISMDILSQVSETYRKIRNTLRFLIANTSDFNPAQDVVAYDELRSVDKYMT
                     IRFNQLVKTIRDAYADFEFLTIYKALVNFINVDLSAFYLDFAKDVVYIEGAKSLERRQ
                     MQTVFYDILVKITKLLTPILPHTAEEIWSYLEFEAEDFVQLSELPEAQTFANQEEVLD
                     TWAAFMDFRGQAQKALEEARNAKVIGKSLEAHLTVYPNEVVKTLLEAVNSNVAQLLIV
                     SDLTIAEGPAPEAAVSFEDVAFTVERAAGQVCDRCRRIDPTTAERSYQAVICDHCASI
                     VEENFAEAVAEGFEEK"
     gene            26457..26837
                     /locus_tag="VQ865_000179"
     CDS             26457..26837
                     /locus_tag="VQ865_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134607.1"
                     /translation="MKLKTLALISGIVGLVGGILLLIGPFVLLGTAVNTVATTLNGGA
                     TAGAFSGVALLLNALKIANLVLGIIAIVYYKGDNRVGAAPSVLMIVFGGVSLIPFLGW
                     VGGILVIIGGSLFLATLKKFKSEE"
     gene            27031..27321
                     /locus_tag="VQ865_000180"
     CDS             27031..27321
                     /locus_tag="VQ865_000180"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134608.1"
                     /translation="MIESIRTYADYIDLYKNIFDDYFTKAEEGFKGTAMENNDSFTKL
                     KESTQKLFDAQKKRLNNEDRIETTKNNVIAKHCQTVLSFLVLTSFFVKNCVK"
     gene            27372..28064
                     /locus_tag="VQ865_000181"
     CDS             27372..28064
                     /locus_tag="VQ865_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006703946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate mutase"
                     /protein_id="HET3134609.1"
                     /translation="MVKLVFARHGESEWNKANLFTGWADVDLSEKGTQQAIDAGKLIK
                     EAGIKFDQAYTSVLKRAIKTTNLALEASDQLWVPVEKSWRLNERHYGGLTGKNKAEAA
                     EQFGDEQVHIWRRSYDVLPPNMDRDDEHSAHTDRRYASLDDSVIPDAENLKVTLERAL
                     PFWEDKIAPALKDGKNVFVGAHGNSIRALVKHIKGLSDDEIMDVEIPNFPPLVFEFDE
                     KLNVVSEYYLGK"
     gene            28117..30528
                     /locus_tag="VQ865_000182"
     CDS             28117..30528
                     /locus_tag="VQ865_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3134610.1"
                     /translation="MIRNKKQDYVLAYKQPVSTTYMGWEEEALPIGNGSLGAKVFGLI
                     GAERIQFNEKSLWSGGPLPDSSDYQGGNLQDQYVFLAEIRQALEKRDYNLAKELAEQH
                     LIGPKTSQYGTYLSFGDIHIEFSQQGTTLSQVTDYQRQLNISKALVTTSYVYKGTRFE
                     REAFASFPDDLLVQRFTKEGAETLDFTIELSLTCDLASDGKYEQEKSDYKECKLDITD
                     SHILMKGRVKDNDLRFASYLAWETDGDIRVWSDRVQISGASYANLFLAAKTDFAQNPA
                     SNYRKKLDLEQQVIDLVDTAKEKGYTQLKSRHIEDYQALFQRVQLDLEANVDAFTTDD
                     LLKNYKPQEGQALEELFFQYGRYLLISSSRDCPDALPANLQGVWNAVDNPPWNSDYHL
                     NVNLQMNYWPAYVTNLLEAVFPVINYVDDLRVYGRLAAVKYAGIVSQKGEENGWLVHT
                     QATPFGWTAPGWDYYWGWSPAANAWMMQTVYEAYSFYRDQDYLREKIYPMLRETVRFW
                     NAFLHKDQQAQRWVSSPSYSPEHGPISIGNTYDQSLIWQLFHDFIQAAQELGLDEDLL
                     TEVKEKSDLLNPLQITQSGRIREWYEEEEQYFQNEKVEAQHRHASHLVGLYPGNLFSY
                     KGQEYIEAARASLNDRGDGGTGWSKANKINLWARLGDGNRAHKLLAEQLKTSTLPNLW
                     CSHPPFQIDGNFGATSGMAEMLLQSHAAYLVPLAALPDAWSTGSVSGLMARGHFEVSM
                     SWEDKKLLQLTILSRSGGDLRVSYPDIEKSVIKMNQEKIKAKCMGKDCISVATAEGDL
                     VQFYF"
     gene            30778..31479
                     /locus_tag="VQ865_000183"
     CDS             30778..31479
                     /locus_tag="VQ865_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134611.1"
                     /translation="MAYIEMKHCYKRYQVGDTEIVANRDVNFEIEKGELVIILGASGA
                     GKSTVLNLLGGMDTNDEGEIWIDGVNIADYSSHQRTNYRRNDVGFVFQFYNLVSNLTA
                     KENVELASEIVTDALNPDQVLTDVGLAHRLNNFPAQLSGGEQQRVSIARAVAKNPKIL
                     LCDEPTGALDYQTGKQVLKILQDMSRQKGATVIIVTHNGALAPIADRVIHMHDASVKD
                     VVLNQHPQDIDSLEY"
     gene            31481..34189
                     /locus_tag="VQ865_000184"
     CDS             31481..34189
                     /locus_tag="VQ865_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3134612.1"
                     /translation="MIKRKTYWKDLIQSFTDSKGRFLSILILMMLGSLALVGLKVTSP
                     NMEATANAYLTTAQTLDLAVMSNYGLDQADQEELKQTEGAEVEFGYLTDVTMDNGQDA
                     IRLYSKPERISTFQLRKGRLPQSDREIALATHLQGQYSVGQEISFKEKEEGHSSLKDH
                     TYTITGFVDSAEILSQRDMGYAGSGSGTLTAYGVILPSQFDQKVYNIARLKYQDLAGL
                     NAFSSAYEEKSKQHQEDLEQTLSDNGKVRLQLLKKEGQESLDKGQETLDKAQTNLQEG
                     KRRLAAAQARIQAQESQLALFPQAQREQASAQLTQAKQELGKEEDKLKQAEQNLAQEK
                     EKLEKHQQVLDDLAEPRYQVYNRQTMPGGQGYLMYSNASSSIRAVGNIFPVVLYAVAA
                     MVTFTTMTRFVDEERTHAGIFKALGYRSKDIIAKFLLYGLVAGTVGTALGSILGHYLL
                     ASVISSVITKGMVVGETQIQFYWTYSLLALVLSWLASVLPAYLVAWRELHDEAAQLLL
                     PKPPVKGAKILLERIGFIWRRLSFTHKVTARNIFRYKQRMLMTIFGVAGSVALLFAGL
                     GIQSSVAGVPSKQFQQIQQYQMLVSENPSATNQDKVELAEVLKGQEILAYQKIYSKTL
                     DKDFKGRAGLQNITLMMIEKEDLTPFIHLQHHQQELTLKDGIVITAKLAQLAGVKVGQ
                     TLEIEGKELKVAAITENYVGHFIYMSQASYEQLYGQLPQANTYLVSLRDTSATSIESQ
                     AGLLMNQSAVSSVVQNASAIRLFDSIASSLNQTMTILVIVSVLLAIVILYNLTNINVA
                     ERIRELSTIKVLGFHNNEVTLYIYRETIVLSLVGIVLGLVAGFYLHQFLIQMISPATI
                     LFYPQVGWEVYVIPVAAVSIILTLLGFFVNYYLRKVDMLEALKSVE"
     gene            complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ865_000185"
     CDS             complement(34285..34776)
                     /gene="tpx"
                     /locus_tag="VQ865_000185"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HET3134613.1"
                     /translation="MVTFLGNPVSFTGKQLQVGDKALDFSLTTTDLSKKSLADFDGKK
                     KVLSVVPSIDTGICSTQTRRFNEELAGLDNTVVLTVSMDLPFAQKRWCGAEGLDNAIM
                     LSDYFDHSFGRDYALLINEWHLLARAVFVLDTDNTIRYVEYVDNINSEPNFEAAIAAA
                     KAL"
     gene            complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ865_000186"
     CDS             complement(34899..35828)
                     /gene="psaA"
                     /locus_tag="VQ865_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000733059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding
                     lipoprotein/adhesin PsaA"
                     /protein_id="HET3134614.1"
                     /translation="MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIAD
                     ITKNIAGDKIDLHSIVPIGQNPHEYEPLPEDVKKTSEADLIFYNGINLETGGNAWFTK
                     LVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
                     KDPNNKEFYEKNLKEYTDKLDKLDKESKDKFNKIPAEKKLIVTSEGAFKYFSKAYGVP
                     SAYIWEINTEEEGTPEQIKTLVEKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQ
                     IFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK"
     gene            complement(35860..36708)
                     /locus_tag="VQ865_000187"
     CDS             complement(35860..36708)
                     /locus_tag="VQ865_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000559784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3134615.1"
                     /translation="MIAEFIDGLQKFHFLQNALITAIVVGIVAGAVGCFIILRGMSLM
                     GDAISHAVLPGVALSFILGLDFFIGAIVFGLLAAIIITYIKGNSIIKSDTAIGITFSS
                     FLALGIILIGVAKSSTDLFHILFGNILAVQDTDMFITMGVGAAILLLIWIFFKQLLIT
                     SFDELLAKAMGMPVNFYHYLLMVLLTLVSVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKSMIFLSSTFGATASVLGLFIGYSFNVAAGSSIVLTAASFFLISFFIAPKQRYLKLK
                     NKHLLK"
     gene            complement(36705..37427)
                     /locus_tag="VQ865_000188"
     CDS             complement(36705..37427)
                     /locus_tag="VQ865_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3134616.1"
                     /translation="MIRIENLSVSYKETLALKDISLVLHGPTITGIIGPNGAGKSTLL
                     KGMLGIIPHQGQAFLDDKEVKKSLHRIAYVEQKINIDYNFPIKVKECVSLGLFPSIPL
                     FRSLKAKHWKKVQEALEIVGLADYAERQISQLSGGQFQRVLIARCLVQEADYILLDEP
                     FAGIDSVSEEIIMNTLRDLKKAGKTVLIVHHDLSKIPHYFDQVLLVNREVIAFGPTKE
                     TFTETNLKEAYGNQLFFNGGDL"
     gene            37718..39610
                     /gene="pepO"
                     /locus_tag="VQ865_000189"
     CDS             37718..39610
                     /gene="pepO"
                     /locus_tag="VQ865_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase PepO"
                     /protein_id="HET3134617.1"
                     /translation="MTRYQDDFYDAINGEWQQTAEIPADKSQTGGFVDLDQEIEDLML
                     ATTDKWLAGEEVPEDAILENFVKYHRLVRDFDKREADGITPVLPLLKEFQELETFADF
                     TAKLAEFELAGKPNFLPFGVSPDFMDARINVLWASAPSTILPDTTYYAEEHPQREELL
                     TLWKESSANLLKAYDFSDEEIEDLLEKRLELDRRVAAVVLSNEESSEYAKLYHPYSYE
                     DFKKFAPALPLDDFFKAVIGQLPDKVIVDEERFWQAAEQFYSEEAWSLLKATLILSVV
                     NLSTSYLTEDIRVLSGAYSRALSGVPEAKDKVKAAYHLAQEPFKQALGLWYAREKFSP
                     EAKADVEKKVATMIDVYKERLLKNDWLTPETCKQAIVKLNVIKPYIGYPEELPARYKD
                     KVVNETASLFENALAFARVEIKHSWSKWNQPVDYKEWGMPAHMVNAYYNPQKNLIVFP
                     AAILQAPFYDLHQSSSANYGGIGAVIAHEISHAFDTNGASFDENGSLKDWWTESDYAA
                     FKEKTQKVIDQFDGQDSYGATINGKLTVSENVADLGGIAAALEAAKREADFSAEEFFY
                     NFGRIWRMKGRPEFMKLLASVDVHAPAKLRVNVQVPNFDDFFTTYDVKEGDGMWRSPE
                     ERVIIW"
     gene            complement(39733..40362)
                     /locus_tag="VQ865_000190"
     CDS             complement(39733..40362)
                     /locus_tag="VQ865_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3134618.1"
                     /translation="MKIHKTVNPVAYENTYYLEGEKHLIVVDPGSHWEAIRQTIEKIN
                     KPICAILLTHAHYDHIMSLDLVRETFGNPPVYIAESEASWLYTPVDNLSGLPRHDDMA
                     DVVTKPAEHTFVFHEEYQLEEFRFKVLPTPGHSIGGVSLVFPDAHLVLTGDALFRETI
                     GRTDLPTGSMEQLLHSIQTQLFTLPNYDVYPGHGPATTIAHEKAFNPFF"
     gene            41358..43580
                     /locus_tag="VQ865_000191"
     CDS             41358..43580
                     /locus_tag="VQ865_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019316080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HET3134619.1"
                     /translation="MPKEVNLTGEEVVALTKEYLTEEDVHFVHKALVYAVECHSGQYR
                     KSGEPYIIHPIQVAGILAKLKLDAVTVACGFLHDVVEDTDATLDDLEREFGPDVRMIV
                     DGVTKLGKVEYKSIEEQLAENHRKMLMAMSEDIRVILVKLSDRLHNMRTLKHLRKDKQ
                     ERISKETMEIYAPLAHRLGISSVKWELEDLSFRYLNPTEFYKITHMMKEKRREREALV
                     DEVVTKLEEYTTERHLKGKIYGRPKHIYSIFRKMQDKRKRFEEIYDLIAIRCILDTQS
                     DVYAMLGYVHEFWKPMPGRFKDYIANRKANGYQSIHTTVYGPKGPIEFQIRTKEMHEV
                     AEYGVAAHWAYKKGIKGQVNSKESAIGMNWIKEMMELQDQADDAKEFVDSVKENYLAE
                     EIYVFTPDGAVRSLPKDSEPIDFAYEIHTKVGEKATGAKVNGRMVPLTTKLKTGDQVE
                     IIANPNSFGPSRDWLNMVKTSKARNKIRQFFKNQDKELSVNKGREMLMAQFQENGYVA
                     NKFMDKRHMDQVLQKTSYKTEDSLFAAIGFGEIGAITVFNRLTEKERREEERAKAKAE
                     AEELVKGGEVKVENKETLKVKHEGGVVIEGASGLLVRIAKCCNPVPGDDIVGYITKGR
                     GVAIHRVDCMNLRAQENYEQRLLDVEWEDQYSSSNKEYMAHIDIYGLNRTGLLNDVLQ
                     VLSNTTKNISTVNAQPTKDMKFANIHVSFGIANLSTLTTVVDKIKSVPEVYSVKRTNG
                     "
     gene            43610..44053
                     /locus_tag="VQ865_000192"
     CDS             43610..44053
                     /locus_tag="VQ865_000192"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HET3134620.1"
                     /translation="MKIIIQRVKKAQVSIEGQIQGKINQGFLLLVGVGPEDQEEDLDY
                     AVRKLVNMRIFSDAEGKMNLSVKDIEGEILSISQFTLFADTKKGNRPAFTGAAKPDMA
                     SDFYDAFNQKLAQEVPVQTGIFGADMQVELVNNGPVTIILDTKKR"
     gene            complement(44320..44505)
                     /locus_tag="VQ865_000193"
     CDS             complement(44320..44505)
                     /locus_tag="VQ865_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134621.1"
                     /translation="MKKIIFIKTIQLLVIDGIMLAFLTFKRELTWDWILIYSGWLIFF
                     HPVLLTYLSNQLCDHFS"
     gene            complement(44524..44937)
                     /locus_tag="VQ865_000194"
     CDS             complement(44524..44937)
                     /locus_tag="VQ865_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134622.1"
                     /translation="MKKLYRIHFIAIAVIDLLLFAFFITRLETSFEWLLLSGLIFFLD
                     QGLLLFLLVVRLKHQFAEIYPQINKKIRFYYLGILTIDFLFFVLLAFISSQRFSSLMP
                     IITARHSTFYYMTADYLGENYPDFYDKHISLWECL"
     gene            complement(45068..45715)
                     /locus_tag="VQ865_000195"
     CDS             complement(45068..45715)
                     /locus_tag="VQ865_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HET3134623.1"
                     /translation="MVVGIAIASGYLNSRLHKFVDWGLWTALVPFGLISVTNVGISML
                     STRFTGKLSKWGNYFGIVNTILSGAIDYILGNKAAIITYPVTFLIYTFAIKKWKASQE
                     GRPNQMSQKQVKLAPIIISIIAFLFAFVTNYIGYGGKMNLLAYVTTIAFALSLIANAL
                     NALKLTTQWGFWLIYNFVQLTKAGIQGNFANIGKYIFYILNAIGALFVWNDEEVR"
     gene            complement(45741..45932)
                     /locus_tag="VQ865_000196"
     CDS             complement(45741..45932)
                     /locus_tag="VQ865_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134624.1"
                     /translation="MSRKSTNFSSPLPTLKVLFSGFYFYHFILLSFGVRIFEKNGRIF
                     EKKKGSLTYEKITKNFCYI"
     gene            complement(45913..46563)
                     /locus_tag="VQ865_000197"
     CDS             complement(45913..46563)
                     /locus_tag="VQ865_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HET3134625.1"
                     /translation="MTPNKEDYLKCIYEIGIDLHKITNKEIAARMQVSPPAVTEMIKR
                     MKSENLILKDKECGYLLTDLGLKLVSELYRKHRLIEVFLVHHLDYTSDQIHEEAEVLE
                     HTVSDLFVERLDKLLGFPKTCPHGGTIPAKGELLVEINNLPLADIKEAGAYRLTRVHD
                     SFDILHYLDKHSLHIGDQLQVKQFDGFSNTFTILSNDEDLQVNMDIAKQLYVEKIN"
     gene            46675..47517
                     /locus_tag="VQ865_000198"
     CDS             46675..47517
                     /locus_tag="VQ865_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3134626.1"
                     /translation="MTKIALLSDIHGNTTALEAVLADARQIGVDEYWLLGDILMPGTG
                     RRRILDLLDQLPITARVLGNWEDSLWHGVRKELDSTRPSQRYLLRQCQYVLEEISLEE
                     IEVLHNQPLQIHRQFGDLTVGISHHLPDKNWGRELIHTGKQEDFDRLVTHPPCDIAVY
                     GHIHQQLLRYGTGGQLIVNPGSIGQPFFLDAQLRKDLRAQYMILEFDDKGLVDMDFRR
                     VDYDVAAELQLAKDLRLPYFEVYYESLVNGIHHTHHQEFLRELAQKEGCDRELDDWLK
                     SGND"
     gene            47593..48030
                     /locus_tag="VQ865_000199"
     CDS             47593..48030
                     /locus_tag="VQ865_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HET3134627.1"
                     /translation="MQIPSRFTIATHMLIIIALEGKESKVTSDFLAASVGVNPVIIRK
                     ILSQLKKAELISVARGTGGTEIVKDLKDISLLDVYQAVECLGKTGQLFSFHDNPNPNC
                     PVGAHIHDVLDQKLERIQLTMEAELGQTSLEKVVADAESQMKD"
     gene            48098..48400
                     /locus_tag="VQ865_000200"
     CDS             48098..48400
                     /locus_tag="VQ865_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000281600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134628.1"
                     /translation="MYLVIGIVLAFIVSFWKDNRSLWNPVLFLLSLISSYFYLSYLFY
                     KNGYENVQLAFYVFAFVLLPFLLFLSGIFLIYNGVILLKREGRSKPHYLSMLFDFY"
     gene            complement(48491..49564)
                     /locus_tag="VQ865_000201"
     CDS             complement(48491..49564)
                     /locus_tag="VQ865_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2974 domain-containing protein"
                     /protein_id="HET3134629.1"
                     /translation="MANIFDYLKDVAYDSYYDLPLNELDILTLIEITYLSFDNLVSTL
                     PQRLLDLAPQVPRDPTMLTSKNRLQLLDELAQHKRFKNCKLSHFINDIDPELQKQFAA
                     MTYRVSLDTYLIVFRGTDDSIIGWKEDFHLTYMKEIPAQKHALRYLKNFFAHHPKQKV
                     ILAGHSKGGNLAIYAASQIEQSLQNQITAVYTFDAPGLHQELTQTAGYQRIMDRSKIF
                     IPQGSIIGMMLEIPAHQIIVQSTALGGIAQHDTFSWQIEDKHFVQLDKTNSDSQQVDT
                     TFKEWVATVPDEELQLYFDLFFGTILEAGISSINDLASLKALEYIHHLFVQAQSLTPE
                     ERETLGRLTQLLIDTRYQAWKNR"
     gene            49720..50397
                     /locus_tag="VQ865_000202"
     CDS             49720..50397
                     /locus_tag="VQ865_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3134630.1"
                     /translation="MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQS
                     EPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSSRDQAMDIVMAINMGADDFVTKP
                     FDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
                     RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGI
                     GYGLKHA"
     gene            50390..51364
                     /locus_tag="VQ865_000203"
     CDS             50390..51364
                     /locus_tag="VQ865_000203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3134631.1"
                     /translation="MLDWKQFFLAYLRSRSRLFIYLLSLAFLVLLFQFLFASLGIYFL
                     YFFFLCCFVTILFFTWDILVETQVYRQELLYGEREAKSPLEIALAEKLEAREMELYQQ
                     RSKAERKLTDLLDYYTLWVHQIKTPIAASQLLVAEVVDRQLKQQLEQEIFKIDSYTNL
                     VLQYLRLESFHDDLVLKQVQIEDLVKEIIRKYALVFIQKGLNVNLHDLDKEIVTDKKW
                     LLVVIEQIISNSLKYTKEGGLEIYMDDQELCIKDTGIGIKNSDVLRVFERGFSGYNGR
                     LTQQSSGLGLYLSKKISEELGHQIRIESEVGKGTTVRIQFAQVNLVLE"
     gene            complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ865_000204"
     CDS             complement(51413..53356)
                     /gene="thrS"
                     /locus_tag="VQ865_000204"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HET3134632.1"
                     /translation="MINITFPDGAVREFESGVTTFEIAQSISNSLAKKALAGKFNGKL
                     IDTTRAITEDGSIEIVTPDHEDALPILRHSAAHLFAQAARRLFPDIHLGVGPAIEDGF
                     YYDTDNTAGQISNEDLPRIEEEMQKIVKENFPSIREEVTKDEAREIFKNDPYKLELIE
                     EHSEDEGGLTIYRQGEYVDLCRGPHVPSTGRIQIFHLLHVAGAYWRGNSDNAMMQRIY
                     GTAWFDKKDLKNYLQMREEAKERDHRKLGKELDLFIISQEVGQGLPFWLPNGATIRRE
                     LERYIVNKELASGYQHVYTPPLASVELYKTSGHWDHYQEDMFPTMDMGDGEEFVLRPM
                     NCPHHIQVFKHHVHSYRELPIRIAEIGMMHRYEKSGALTGLQRVREMSLNDGHLFVTP
                     EQIQEEFQRALQLIIDVYEDFNLTDYRFRLSLRDPQDTHKYFDNDEMWENAQTMLRAA
                     LDEMGVNYFEAEGEAAFYGPKLDIQIKTALGKEETLSTIQLDFLLPERFDLKYIGADG
                     EDHRPVMIHRGVISTMERFTAILIENYKGAFPTWLAPHQVTLIPVSNEKHVDYAWEVA
                     KKLRDRGVRADVDERNEKMQFKIRASQTSKIPYQLIVGDKEMEDETVNVRRYGQKETQ
                     TVSVDNFVQAILADIANKSRVEK"
     gene            complement(53414..53737)
                     /locus_tag="VQ865_000205"
     CDS             complement(53414..53737)
                     /locus_tag="VQ865_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000422771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like protein"
                     /protein_id="HET3134633.1"
                     /translation="MELQELVERSWAIRQAYHELEVKHHDSKWTVEEDLLALSNDIGN
                     FQRLVMTKQGRYYDETPYTLEQKLSENIWWLLELSQRLDIDILTEMENFLSDKEKQLN
                     VRTWK"
     gene            54596..55225
                     /locus_tag="VQ865_000206"
     CDS             54596..55225
                     /locus_tag="VQ865_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HET3134634.1"
                     /translation="MKLAVIAANGQAGKAIVEEAVKRGHEVTAIVRSENKSQAESIIK
                     KDLFELTKDDLTGFDAVISAFGAYTPDTLPLHSKSIELFNQLLAGTQTRFLVVGGSGS
                     FYIDETKTTRLLDTSDFPEEFKPLAKAQADELDLLRTKNNLNWTFVSPAVDFIPDGEK
                     TGNYILAGEIFTTNEKGISQISYADYAIGLVDELEKGHHIKERISLLEK"
     gene            55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ865_000207"
     CDS             55366..55635
                     /gene="rpsO"
                     /locus_tag="VQ865_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HET3134635.1"
                     /translation="MAISKEKKNEIIAQYARHEGDTGSVEVQVAVLTWEINHLNEHIK
                     QHKKDHATYRGLMKKIGRRRNLLAYLRKNDVNRYRELINSLGLRR"
     gene            56451..57065
                     /locus_tag="VQ865_000208"
     CDS             56451..57065
                     /locus_tag="VQ865_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000531723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CadD family cadmium resistance transporter"
                     /protein_id="HET3134636.1"
                     /translation="MGQTIISAIGVYISTSIDYLIILIILFAQLSQNKQKWHIYAGQY
                     LGTGLLVGASLVAAYVVNFVPEEWMVGLLGLIPIYLGIRFAILGEDAEEEEEEIIERL
                     EQSKANQLFWTVTLLTIASGGDNLGIYIPYFASLDWSQTLVALLVFVIGIIIFCEISR
                     VLSSIPLIFETIEKYERIIVPLVFILLGLYIMYENGTIETFLIV"
     gene            complement(57358..58107)
                     /locus_tag="VQ865_000209"
     CDS             complement(57358..58107)
                     /locus_tag="VQ865_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HET3134637.1"
                     /translation="MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRT
                     WWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINV
                     LKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDM
                     NFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPAL
                     ILAIILAILTIIFSFIASFIWNPDKKREELA"
     gene            58240..60576
                     /locus_tag="VQ865_000210"
     CDS             58240..60576
                     /locus_tag="VQ865_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HET3134638.1"
                     /translation="MDKNKIMGLTQREVKERQAEGLVNDFTASASTSTWQIVKRNVFT
                     LFNALNFAIALALAFVQAWSNLVFFAVICFNAFSGIVTELRAKHMVDKLNLMTKEKVK
                     TIRDGQEVALNPEELVLGDVIRLSAGEQIPSDALVLEGFAEVNEAMLTGESDLVQKEV
                     DGLLLSGSFLASGSVLSQVHHVGADNYAAKLMLEAKTVKPINSRIMKSLDKLAGFTGK
                     IIIPFGLALLLEALLLKGLPLKSSVVNSSTALLGMLPKGIALLTITSLLTAVIKLGLK
                     KVLVQEMYSVETLARVDMLCLDKTGTITQGKMQVEAVLPLTETYGEEAIASILTSYMA
                     HSEDKNPTAQAIRQRFVGDVAYPMISNLPFSSDRKWGAMELEGLGTVFLGAPEMLLDS
                     EVPEAREALERGSRVLVLALSQEKLDHHKPQKPSDIQALALLEILDPIREGAAETLNY
                     LRSQEVGLKIISGDNPVTVSSIAQKAGFADYHSYVDCSKITDEELIALAEETAIFGRV
                     SPHQKKLIIQTLKKAGHTTAMTGDGVNDILALREADCSIVMAEGDPATRQIANLVLLN
                     SDFNDVPEILFEGRRVVNNIAHIAPIFLIKTIYSFLLAVICIASALLGRSEWILIFPF
                     IPIQITMIDQFVEGFPPFVLTFERNIKPVEPNFLRKSMLRALPSALMVVFSVLFVKIF
                     GTSQGWSELEISTLLYYLLGSIGFLSVFRACMPFTLWRVLLIVWSVGGFLATALFPRI
                     QKLLEISTLTEQTLPVYGVMMLVFTVIFILTSRYQARK"
     gene            61105..62568
                     /locus_tag="VQ865_000211"
     CDS             61105..62568
                     /locus_tag="VQ865_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3134639.1"
                     /translation="MSRKQEQMETLLLLLRDSKDYISAKVLGEKLNCSDKTVYRLVKV
                     INKDCPVEAFILSEKGRGFKLNPRSSLVDVDGNFTEAFDPEVRREKLLERLLLTAPKP
                     HSIYDLGEEFYVSESVVLKDRQILQESLAIYGLDLKMRQRKLFIDGDEAQIRSAILNL
                     LPMFNQLDLEQITQNKVQPLDGELAHFCLGLLITLERELGVNIPYPYNINIFSHLYIF
                     ISRNRRSTSIHVVAPSKPTIVDEKIYSVCQKIIQEIEQYFKMKVDAVEIDYLYQYVVS
                     SRLQKPFSSGKLPFSQRVLDVTHYYFSRMCMDNREIETTDPDFVDLASHISPLLRRLD
                     NRVQIKNSLLSQILLTYPNLVKELTTISKEVSLVFGFASLSLDEIGFLVLYFARFQEK
                     RARPLKTVVMCTSGVGTSELLRARLEKQFTELDIIDVVAYHQLDELINLYPDLDFIVT
                     TVALQEPASVPFVLVSVFLTEGDKQRLQAKIQEINYE"
     gene            62561..62989
                     /locus_tag="VQ865_000212"
     CDS             62561..62989
                     /locus_tag="VQ865_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3134640.1"
                     /translation="MNNLSLVLMDISVQNRQEAYKELANQISLLVSEDTEKIEELLYY
                     RERQGSIEVAKGVLLPHCEGNFQHHVLVITRLKSPIREWSKDIQCVDLIIGLAIAVSQ
                     DKSCIKTLMRRLADESFINQLKQLTKEELREIIYGNQRYS"
     gene            62967..63416
                     /locus_tag="VQ865_000213"
     CDS             62967..63416
                     /locus_tag="VQ865_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3134641.1"
                     /translation="MEIKDILNVSLIQTDLQMQSKEEVFEALAQLLVETGYVSDRDQF
                     IEGLYQREAEGQTGIGNYIAIPHSKSSAVEKAGVVIAINHNEIPWETIDGKGVKVIVL
                     FAVGDDTEAAREHLKTLSLFARKLGNDEVVAKLVRAQTSDDVIAAFC"
     gene            63444..63755
                     /locus_tag="VQ865_000214"
     CDS             63444..63755
                     /locus_tag="VQ865_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HET3134642.1"
                     /translation="MKIVGVAACTVGIAHTYIAQEKLENAAKVAGHVIHVETQGTIGV
                     ENELSQEQIDAADVVILAVDVKISGMERFEGKKIIKVPTEVAVKSPNKLIAKAVEIVT
                     K"
     gene            63781..64866
                     /locus_tag="VQ865_000215"
     CDS             63781..64866
                     /locus_tag="VQ865_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HET3134643.1"
                     /translation="MLKHLNLKGHLLTAISYMIPIVCGAGFLVAIGLAMGGGVPDALV
                     AGKFTIWDALATMGGKALGLLPVVIATGLSYSIAGKPGIAPGFVVGLIANSVGSGFIG
                     GILGGYIAGFLVQAIIKKVKVPNWIKGLMPTLIIPFVASLVSSLIMIYIIGAPIAAFT
                     NWLTSLLQSLGSASNGLMGAVIGVLSAVDFGGPLNKTVYAFVLTLQAEGVKEPLTALQ
                     LVNTATPVGFGLAYFIAKLLKKNIYTQEEIETLKSAVPMGIVNIVEGVIPIVMNNLVP
                     GLIATGIGGAVGGAVSLTMGADSAVPFGGVLMLPTMTRPVAGICALLANIVVTGLVYA
                     ILKKPIKHTEPVMTVEEEIDLSDIEIL"
     gene            64877..65572
                     /locus_tag="VQ865_000216"
     CDS             64877..65572
                     /locus_tag="VQ865_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000086495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3134644.1"
                     /translation="MSRIEFSPSLMTMDLDKFKEQITFLNDKVASYHIDIMDGHFVPN
                     ITLSPWFIQEVQKISDTPLSVHLMVTDPTFWVDQVLDLQCEYICIHAEVLNGLAFRLI
                     DKIHDAGLKAGVVLNPETPVSTIFPYIDLLDKVTIMTVDPGFAGQRFLKSTLYKIQEL
                     RQLRVQNGYHYIIEMDGSSSRKTFKQIDVAGPDIYVIGRSGLFGLDDDIAKAWDICSR
                     DYEEMTGKTMPIK"
     gene            65609..67579
                     /gene="tkt"
                     /locus_tag="VQ865_000217"
     CDS             65609..67579
                     /gene="tkt"
                     /locus_tag="VQ865_000217"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3134645.1"
                     /translation="MSLQSVNAIRFLGVDAINKSNSGHPGIVMGAAPMAYSLFTKHLR
                     ITPEQPNWINRDRFILSAGHGSMLLYALLHLTGYKDVSMDEIKNFRQWGSKTPGHPEV
                     THTSGVDATSGPLGQGISTAVGFAQAERFLAAKYNKDGFPIFDHYTYVIAGDGDFMEG
                     VSAEAASYAGHQALDKLIVLYDSNDICLDGETKDTFSENVRARYDAYGWHTVLVEDGT
                     DLAAISTAIETAKFSGKPSLIEVKTVIGYGSPNKSGTNAVHGAPLGAEETGATRKFLG
                     WDYDPFEVPEEVYSDFKTNVADRGQEAYDAWASLVSDYKVAYPEVASEIDAIVAGKSP
                     VTITEKDFPVYENGFSQATRNSSQDAINTAAAVLPTFLGGSADLAHSNMTYIKADGLQ
                     DKYNPLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAIRLSAIQEL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRSMPNLTVIRPADARETQAAWHHALTSTT
                     TPTVIVLTRQNLVVEEGTDFGKVAKGAYVVYDTPGFDTIIIATGSEVNLAIKAAKELV
                     LQGGKVRVVSMPSTELFDAQDATYKEDILPSKTRRRVAIEMAATQSWYKYVGLDGAVI
                     GIDIFGASAPAQTVIDNYGFTVENIVAQVKSL"
     gene            67952..>68088
                     /locus_tag="VQ865_000218"
     CDS             67952..>68088
                     /locus_tag="VQ865_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3134646.1"
                     /translation="MKLSYEDKVQIYELRKQGQSFKQLSKRFGVDVSGLKYMVKLIDR
                     YG"
BASE COUNT        20141 a        12446 c        15283 g        20218 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggcatc gttgttggtg
       61 gcgccattac tagaccaaaa gagattacag aacgcttcgt tgctagtctt aaataagatg
      121 tgagagggag ttttatgttt aaagttttac aaaaagttgg aaaagctttt atgttaccta
      181 tagctatact tcctgcagca ggtctacttt tggggattgg tggtgcactt tcaaacccaa
      241 ccacgatagc aacttatcca atactagaca atagtatttt tcaatcaata ttccaagtaa
      301 tgagctctgc aggagaggtt gtattcagta atttgtcact acttctctgt gtgggattat
      361 gtattggctt agcgaaacga gataaaggaa ccgctgcgtt agcaggagta actggttact
      421 tagttatgac tgcaacgatc aaagctttgg taaaactttt tatggcagaa ggatctgcaa
      481 ttgatactgg agttattgga gcattagttg tcggaatagt tgccgtatat ttgcacaacc
      541 gatataacaa tattcaatta ccttccgctt taggattctt tggaggttca cgcttcgttc
      601 ctattgttac atcgttctct tctatcttga ttggctttgt cttctttgtt atttggccac
      661 ctttccaaca acttcttgtt tctacaggtg gatatatttc tcaggcgggt ccaattggaa
      721 cttttctata tggattttta atgagacttt ctggagcagt aggcttacat catataattt
      781 accctatgtt ttggtatact gaacttggtg gtgttgagac tgttgcagga caaacagtgg
      841 ttggagctca aaaaatattt tttgctcaat tagccgatcc ggcccattct ggattattta
      901 cagaaggaac aaggtttttt gcaggtcgtt tctcaacaat gatgttcggt ttaccggctg
      961 cctgtttagc gatgtaccat agtgttccta aaaatcgtcg taaaaaatac gcgggtttgt
     1021 tttttggagt tgctttaaca tcttttatta ccggtattac agaaccaatt gaatttatgt
     1081 ttctattcgt cagtccggtt ctatatgttg ttcacgcatt ccttgatggt gttagcttct
     1141 ttattgcaga cgtcttaaat atttcaatag gaaacacatt ttcaggaggt gtaatcgatt
     1201 tcactttatt tggaattttg caggggaacg ctaagacgaa ttgggttctt cagattccaa
     1261 ttggacttat ttggagtgtt ttgtattata ttatttttag atggttcatt actcaattca
     1321 acgttctaac gccaggacga ggagaagaag tagattctaa agaaatttct gaatccgcag
     1381 attcaacttc aaatactgca gattatttaa aacaggatag cctacaaatt atcagagcct
     1441 tgggtggatc aaataatata gaagatgtag atgcttgtgt gacacgttta cgtgtagctg
     1501 taaaagaagt taatcaagtt gataaagcac ttttaaaaca aattggtgca gttgatgtct
     1561 tagaagtgaa gggtggcatt caagcaatct atggagcaaa agcaatctta tataaaaata
     1621 gtattaatga aattttaggt gtagatgatt aagtacttac tgacttaata aaaaacagag
     1681 gagagtgatg gatgagtagg atgaaatgaa atcgcataca agaaataaag aactcattat
     1741 ccaagttgga tacgcttatt acataggaga atacaaatga aatttagaaa attagcttgt
     1801 acagtacttg cgggtgctgc ggttcttggt cttgctgctt gtggcaattc tggcggaagt
     1861 aaagatgctg ccaaatcagg tggtgacggt gccaaaacag aaatcacttg gtgggcattc
     1921 ccagtattta cccaagaaaa aactggtgac ggtgttggaa cttatgaaaa atcaatcatc
     1981 gaagcgtttg aaaaagcaaa tccagatata aaagtgaaat tggaaaccat cgacttcaag
     2041 tcaggtcctg aaaaaatcac aacagccatc gaagcaggaa cagctccaga cgtactcttt
     2101 gatgcaccag gacgtatcat ccaatacggt aaaaacggta aattggctga gttgaacgac
     2161 ctcttcacag atgaatttgt taaagatgtc aacaatgaaa acatcgtaca agcaagtaaa
     2221 gctggagaca aggcttatat gtatccgatt agttctgccc cattctacat ggcaatgaac
     2281 aagaaaatgt tagaagatgc tggagtagca aaccttgtaa aagaaggttg gacaactgat
     2341 gattttgaaa aagtattgaa agcacttaaa gacaagggtt acacaccagg ttcattgttc
     2401 agttctggtc aagggggaga ccaaggaaca cgtgccttta tctctaacct ttatagcggt
     2461 tctgtaacag atgaaaaagt tagcaaatat acaactgatg atcctaaatt cgtcaaaggt
     2521 cttgaaaaag caactagctg gattaaagac aatttgatca ataatggttc acaatttgac
     2581 ggtggggcag atatccaaaa ctttgccaac ggtcaaacat cttacacaat cctttgggca
     2641 ccagctcaaa atggtatcca agctaaactt ttagaagcaa gtaaggtaga agtggtagaa
     2701 gtaccattcc catcagacga aggtaagcca gctcttgaat accttgtaaa cggatttgca
     2761 gtattcaaca ataaagacga caagaaagtc gctgcatcta agaaattcat ccagtttatc
     2821 gcagatgaca aagagtgggg acctaaagac gtagttcgta caggtgcttt cccagtccgt
     2881 acttcatttg gaaaacttta tgaagacaaa cgcatggaaa caatcagcgg ctggactcaa
     2941 tactactcac catactacaa cactattgat ggatttgctg aaatgagaac gctttggttc
     3001 ccaatgttgc aatctgtatc aaatggtgac gaaaaaccag cggatgcttt gaaagccttc
     3061 actgaaaaag caaacgaaac aatcaaaaaa gctatgaaac aatagtcctt agttattcta
     3121 tgaaaaagta attttttaaa gaacctaaga gtgtataccc ccttttccct ctacacagat
     3181 agtgtaagaa aagggggctt ttgtttaaaa tgtaagaaac tgtcacgaaa ttaaaatgaa
     3241 gttcttacat aagcgaatca taaaaaattt cattttgatt ttaaaacagt tcaagaaagt
     3301 caaaaaatta ttctatttga aagagaggtg ccgactgtga aagtcaataa aatccgtatg
     3361 cgggaaacag tgatttccta cgctttccta gcaccagtat tattcttctt tgtcatcttt
     3421 gtgttggctc cgatggtgat gggcttcatt acaagtttct ttaactactc aatgactaaa
     3481 tttgagtttg tgggcttaga taactatatc cgtatgttta aagatcctgt ctttacaaaa
     3541 tctctgatta acacagttat tttggttatt ggatctgtac cagttgttgt tctattctca
     3601 ctctttgtag catctcagac ctatcatcaa aatgtcattg ccagatcctt ctaccgtttc
     3661 gtcttcttcc ttcctgttgt aacgggtagt gttgccgtga cagttgtttg gaaatggatt
     3721 tatgacccac tatcagggat tctaaacttt gtccttaagt caagccacat catcagccaa
     3781 aacatttctt ggttgggaga taaaaactgg gcattgatgg cgattatgat tattctcttg
     3841 accacttcag ttggtcagcc catcatcctt tatatcgctg ccatggggaa tattgacaat
     3901 tcactggttg aagcggcgcg tgttgatggt gcaactgagt ttcaagtttt ctggaagatt
     3961 aaatggccaa gccttcttcc aacaactctt tatattgcaa tcatcacaac aattaactca
     4021 ttccagtgtt tcgccttgat tcagcttttg acatctggtg gtccaaacta ctcaacaagt
     4081 accttgatgt actaccttta cgaaaaagcc ttccaattga cagaatacgg ctatgccaac
     4141 acaattggtg tcttcttggc agtcatgatt gctatcgtaa gctttgttca atttaaagta
     4201 cttggaaacg acgtagaata ctaaagaaag gagacagcta tgcaatctac agaaaaaaaa
     4261 ccattaacag cctttactgt tatttcaaca atcattttgc tcttgttgac tgtgctgttc
     4321 atctttccat tctactggat tttgacaggg gcattcaaat cacaacctga tacaattgtt
     4381 attcctcctc agtggttccc taaaatgcca accatggaaa acttccaaca actcatggtg
     4441 cagaaccctg ccttgcaatg gatgtggaac tcagtattta tctcattggt aaccatgttc
     4501 ttagtttgtg caacctcatc tctagcaggt tatgtattgg ctaaaaaacg tttctatggt
     4561 caacgcattc tatttgctat ctttatcgct gctatggcgc ttccaaaaca agttgtcctt
     4621 gtaccattgg tacgtatcgt caacttcatg ggaatccacg atactctctg ggcagttatc
     4681 ttgcctttga ttggatggcc attcggtgtc ttcctcatga aacaatttag tgaaaatatt
     4741 cctacagagt tgcttgaatc agctaaaatc gacggttgtg gtgagattcg taccttctgg
     4801 agtgtagcct tcccgattgt gaaaccaggg tttgcagccc ttgcaatctt taccttcatc
     4861 aatacttgga atgactactt catgcaattg gtaatgttga cttcacgtaa caatttgacc
     4921 atctcacttg gggttgcgac catgcaggct gaaatggcaa ccaactatgg tttgattatg
     4981 gcaggagctg cccttgctgc tgttccaatc gtcacagtct tcctagtctt ccaaaaatcc
     5041 ttcacacagg gtattactat gggagcggtc aaaggataat actctgagaa aatctcttca
     5101 aactacgtca gcgtcacctt gccatactta agtattgcct gcggttagct tcctagtttg
     5161 ttcttcaatt ttcattgagt ataggaaaat caatctatca agatacagaa gtatatttta
     5221 tagatttaga gaatatagag gttataagtg tctacaaaat ggagggtatg cagttacttt
     5281 atgaagtttt gtcagacact tataaactta agaatggttt tagttaacta tcagaaacga
     5341 aggaaagagt atgatttttg acgatttgaa aaacatcacc ttttacaaag ggattcatcc
     5401 caatttagac aaggctatcg actatctcta ccaacatcgt aaagattcat tcgaattagg
     5461 aaagtatgag attgatggag ataaagtctt tctagttgtt caggaaaatg tcctcaatca
     5521 agttgagaat aatcaatttg aacaccataa gaactatgca gatttgcatt tgctggtaga
     5581 aggacatgaa tattcgagct acggttcacg tatcaaagac gaggcagtag cattcgacga
     5641 agcgactgac attggctttg ttcattgtca tgaacactac ccactcttgt tgggttatca
     5701 taattttgcg attttcttcc caggtgagcc acatcagcca actggctatg caggtatgga
     5761 agaaaaggtt cgaaaatatc tctttaaaat tttgattgat taaaaatagg atgaattgtt
     5821 tttttgtaaa gctttgacaa tactctacca tgaaattgat ctttgtgagg tagagaaatg
     5881 agaataaaat atttaaaaat tggtatcttc taagcatgct gcaagagcta gtttcttaga
     5941 tggacagggg attacagttg atgagatgtc ctggataatt aatggcattg tgaatgcatt
     6001 gattggtaga tacataaaat taggtactta tgcagctaag tatggtatta gtatagcacg
     6061 ctcgatctta agtagggcag ctgcaactgc agcagcaaga gtaggattac tgaccaagat
     6121 ttctggatgg attttacgag tagctgtgaa tgtagctgat gtatatggta attttgccaa
     6181 caatattgct gcagcttggg atgcatatga taaaattcct aacaatggtc gtataaactt
     6241 ttaaaatgcg agaatgaaag cactttgtat ttttttattg aatatgttag cttggacagt
     6301 gcttgcaatg ataattcgtg gagggctaga tggatttgat aggcatactt ggagtactat
     6361 tttaattgct tcgctgttcg gggtatatga ttataagccc atagataaaa atagaaaaaa
     6421 gtccaaaaga aaaaagaaaa aatagatttg ttcatggtag ggacttatga aagctttact
     6481 gacaaaaaag aaaacagttt acaaagaaaa atgatggagg agcaaacatg gcacaaaaag
     6541 gagtaagcct tatcaaggca gcatttgata cagataactt tctcatgcgt tttagtgaga
     6601 aggtcttgga catcgtgaca gccaatcttc tttttgtcgt ctcttgtttg cccatcgtga
     6661 cgattggagt ggctaaaatc agcctctacg agaccatgtt cgaagttaag aagagcagac
     6721 gggtgcctgt ttttaaaatc tatctaagat ctttcaagca aaatctgaaa ctaggtcttc
     6781 agttaggtct gcttgagttg ggcattgttt cattaagcct cctagatctt tatctctttt
     6841 ggggtcaaac agctctgccc tttcaattgc tgaaagctat ttgtctaggc attctgattt
     6901 tccttacgat tgtgatgttg gctagctatc caatcgcggc acgttatgat ttaacttgga
     6961 aagaaattct tcaaaaagga ttgatgttgg ctagttttaa ctttccttgg ttcttcctca
     7021 tgttagccat tcttgtcctc attgtgatgg ttctttatct gtctgccttc agtctactct
     7081 taggtggctc agtcttcctg ctttttgggt ttggactatt ggtctttatc cagactggat
     7141 tgatggagaa aattttcgca aaataccaat aggagcctta tttctgaaac tactttcaaa
     7201 ggctccaaac gctattctat aagcgagaaa ctaaaatcta agtgtctata agatattgaa
     7261 agccttttcg gtaaagtgta tactaaagaa gtaaagaaaa atctgcttta gcagaaaata
     7321 aaaataatag gagaaaatct atgtcagatt tgaaaaaata cgaaggtgtc attccagcct
     7381 tctacgcatg ttatgatgag caaggagaag taagtccaga gcgtacgcgt gccttggttc
     7441 aatacttcat tgataaaggt gttcaaggtc tttatgtcaa tggttcttct ggtgaatgta
     7501 tctaccaaag cgttgaagat cgcaagttga ttttggaaga agtcatggcg gtagccaaag
     7561 gtaaattgac cattattgcc catgttgctt gcaataatac taaagatagt atggaacttg
     7621 ctcgccatgc tgaaagcttg ggagtagatg ctattgcaac gattccacca atttacttcc
     7681 gcttgccaga atactcagtt gccaaatact ggaacgatat tagttctgca gctccaaaca
     7741 cagactacgt gatttacaac attcctcaat tggcaggggt tgctttgact ccaagccttt
     7801 acacagaaat gttgaaaaat cctcgtgtta tcggtgttaa gaactcttct atgccagttc
     7861 aagatatcca aacctttgtc agccttggcg gggaagacca tattgtcttt aacggtccag
     7921 atgaacagtt cctaggtggc cgcctcatgg gtgctaaggc tggtatcggt ggtacttatg
     7981 gtgctatgcc agaactcttc ttgaaactca atcagttgat tgcggataag gacctagaaa
     8041 cagcgcgtga attgcagtat gctatcaacg caatcattgg taaactcact tctgctcatg
     8101 gaaatatgta cggtgtcatc aaagaagtct tgaaaatcaa tgaaggcttg aatattggat
     8161 ctgttcgttc accattgaca ccagtaactg aagaagatcg tccagttgta gaagcggctg
     8221 cagccttgat tcgtgaaacc aaggagcgct tcctctaatc taaaaggagg tatttatgac
     8281 atactacgtt gcaattgata tcggtggaac taacatcaag tatggtttgg ttgatcaaga
     8341 ggggcaactt cttgaatcgc atgaaatgcc aactgaggcg cataagggtg gacctcatat
     8401 cttacaaaag accaaagata tcgtagctag ttatttagaa aaaggcccag tagcaggtgt
     8461 tgccatatct tctgctggga tggtggatcc ggataagggt gagattttct atgctgggcc
     8521 gcaaatccct aactacgcag gcacccagtt caaaaaggaa atcgaagaaa gctttactat
     8581 tccttgtgag attgaaaatg atgtcaactg tgcaggtctt gctgaggcag tatctggttc
     8641 aggcaaggga gcaagtgtga cactttgctt gaccattgga acaggtatcg gtggttgctt
     8701 gattatggat aggaaagtct tccatggttt tagtaattca gcctgtgaag tcgggtatat
     8761 gcatatgcag gatggagctt ttcaagactt ggcttctaca acagctttag tgaaatatgt
     8821 agctgaagcc catggagaag atgttgatca gtggaatggc cgacgtatct ttaaggaagc
     8881 tactgaagga aacaaaatct gcatggaagg tattgaccgt atggttgact atctaggaaa
     8941 aggtctggca aatatttgct acgttgccaa tccagaagtg gttattcttg gtggtggtat
     9001 catggggcaa gaggctatcc tcaaacctaa gatccgcaca gccttgaaag aggctttggt
     9061 accaagttta gcagaaaaaa cacgattaga atttgcccat caccaaaata cagcagggat
     9121 gttgggtgca tattatcatt ttaagacaaa acaatcctag tttggctcag ccaaactagg
     9181 attttcttac acgtttttgt ctacgatagc cgttgagttt tttattttcc cagtagctat
     9241 taaagatttt ttccttgctt tcgcgattga tttccaaaaa gtaggcataa atcaaatcga
     9301 taaagaagag cataggaagt tgagcggata ttcgttggat ataggagggt tggctgtggg
     9361 tggctacaag aacagtctct gtataggtct ggctatcttt attgggaaca cttgtaaaga
     9421 gtacagtctt tgcccccatc tccttggcat ctattagact atctaaaata gaaggagttg
     9481 agcctgaaag tgagaagccc agtactagac aattttcatc catgatgctg gttgtccagg
     9541 caaagccgtc ttggtctgtc aaagcttcgc agaccacacc tagtcgcata aaacgtaatt
     9601 tcatttcacg ggcgacgagg ccagaactcc ctgttccgaa gaagtagata cgctcagcat
     9661 cttcgattag ctgggcaatt cgttctagtt ggatttcgtc aatcaagtct tgtgtttgtt
     9721 ccctcatgtt gctataactt ctgaggactc gtttggtcag tggactgtgc ttggagactt
     9781 ggttggcttg attttctgcc tgatgttggt attggaaaat aaattctcgg tagccagtaa
     9841 agccacactt tttagcaaag cgggtcaaag cagcttgaga aatatgtaat ttttgggtga
     9901 cttgttgaga agataaatca tctgtaatcg tttcagcttg caaaaaatag cgagcgattt
     9961 cttgttctag gtctgtcatt tcttcaaaat gtgaatcaat gatagttgcg atatctggtt
    10021 tgtccatagg gaaagctcct ttacatgagt catactggaa gactagatca gggaatagtc
    10081 acacttcatt ataacacata atataaggat agataaataa aaacgcatct ctgttttaaa
    10141 aacgaaaaaa tcgaaaaagc ttctctcttt tccataattt tctactcaaa ttgtggtaca
    10201 attaagagta agattttaag ttagaaatga gactgatttg tatgagaaaa tttaacagcc
    10261 attcgattcc gattcggctt aatttattgt tttcaatcgt cattttactc tttatgacca
    10321 ttattggtcg tttgttgtat atgcaggttt tgaacaagga tttttacgaa aaaaagctag
    10381 cctcagctag tcagaccaag attacaagca gttcagcccg tggggaaatt tatgatgcta
    10441 gtggaaaacc tttggtagaa aatacgttaa agcaggttgt ttcctttacg cgtagcaata
    10501 aaatgacagc tacagactta aaagaaacag ctaaaaagtt actgacttat gtgagcatca
    10561 gttctccaaa tttgacagaa cgccagctgg cggattacta tttggctgat cctgaaatct
    10621 ataaaaaaac agtggaagct ctcccaagcg agaaacgctt ggattcagat ggcaatcgtc
    10681 tatccgaatc agaactgtat aacaatgcgg tcgatagtgt acaaacgagt caactaaact
    10741 atacagagga tgaaaagaaa gaaatctatc tttttagtca gttaaatgct gttggaaact
    10801 ttgcgacagg aaccattgcg acagatcctc taaatgattc tcaggtggct gttattgcct
    10861 ctatttcaaa ggagatgcct ggcattagta tttctacttc ttgggataga aaggttttgg
    10921 aaacttccct ttcttctata gttgggagtg tatccagtga aaaagctggt ctcccagcgg
    10981 aagaagcaga agcctatctt aaaaaaggct attctctaaa tgatcgtgta ggaacttcct
    11041 atttggaaaa gcaatatgaa gagaccttac aaggaaaacg ctcggtaaaa gaaatccatc
    11101 tggataaata tggcaatatg gaaagcgtgg atacaattga ggaaggtagt aagggaaaca
    11161 atatcaaact gaccattgat ttggctttcc aagatagcgt ggatgcttta ctgaaaagtt
    11221 atttcaattc cgagctagaa aatggtggag ccaagtattc tgaaggtgtc tatgcagtcg
    11281 cccttaaccc aaaaacaggt gcggttttgt ctatgtcagg gattaaacat gacttgaaaa
    11341 cgggagagtt gacgcctgat tccttgggaa cggtaaccaa tgtctttgtt ccaggttcgg
    11401 ttgtcaaggc ggcgaccatc agctcaggtt gggaaaatgg agtcttgtca ggaaaccaga
    11461 ccttgacaga ccagtccatt gtcttccaag gttcagctcc catcaattct tggtatactc
    11521 aggcttacgg ttcattccct atcacagcgg tccaagctct ggagtattca tcaaatacct
    11581 atatggtcca aacagcctta ggtcttatgg ggcaaaccta tcaacccaat atgtttgtcg
    11641 gcaccagcaa tctagagtct gctatggaga aactgcgttc aacctttggc gaatatggct
    11701 tgggtactgc gacaggaatt gacctaccag atgaatctac tggatttgtt cccaaagagt
    11761 atagctttgc taattacatt actaatgcct ttgggcagtt tgataactat acgccgatgc
    11821 agttggctca gtatgtagca actattgcaa ataatggtgt tcgtgtggct cctcgtattg
    11881 ttgaaggcat ttatggtaat aatgataagg gaggactggg taacttgatt cagcaactgc
    11941 aaccgacaga gatgaataag gtcaatatat ccgactccga tatgagcatc ttgcaccaag
    12001 gtttttatca ggttgcccat ggtactagtg gattgacaac tggacgtgcc ttttcaaatg
    12061 gtgccttggt atccattagc ggaaaaacag gtacagccga aagctatgtg gcagatggtc
    12121 agcaagcaac caataccaat gcggtggcct atgccccatc tgataatccc caaatcgctg
    12181 tcgcagtggt ctttcctcat aataccaatc taacaaatgg tgtaggacct tccattgcgc
    12241 gtgacattat caatctgtat caaaaatacc atccaatgaa ttagaaagga aattatgctt
    12301 tatccaacac ctattgccaa gttgattgac agttattcta agttaccagg tatcgggatt
    12361 aagacggcta cgcgtctggc cttttatacg attgggatgt ctgctgatga tgtcaatgaa
    12421 tttgcaaaaa atctcctttc tgctaagaga gaattgacat attgttctat ttgtggacgt
    12481 ttgacagacg acgatccttg ttctatctgt actgatccga ctcgtgacca gacaacaatt
    12541 ttagttcttg aggatagtag agatgtggca gccatggaaa atatccaaga ataccatgga
    12601 ctctatcatg tccttcatgg cctcatttct cctatgaatg gtatcagtcc ggacgatatc
    12661 aatctcaaga gccttatgac tcgtcttatg gatagtgagg tttcagaagt gattgtggcg
    12721 actaatgcta cagcggatgg tgaagcgact tccatgtatc tttcacgttt gctcaagccg
    12781 gctggtatca aggttacgcg tctagcacga ggtctcgctg tgggagcgga cattgagtat
    12841 gcggacgaag tgacactctt acgagcgatt gaaaatcgga cagagttgta agtgtaggca
    12901 aatttacgaa ctccattcat ttataaaaaa tcaaagaggc tgaaaatcgt tcctatcggc
    12961 ctctttttgt atagtgtgat gagtaggatc aggttcaagt tttaaaaaac caagcaaata
    13021 tgatatacta aagagcgagt attctagtag aattaggaca aataagtaga attaggacaa
    13081 ataatatgaa acaaacgatt attcttttat atggtggacg gagtgcggaa cgcgaagtct
    13141 ctgtcctttc agctgagagt gtcatgcgtg cggtcaatta cgaccgtttc acagtcaaga
    13201 ctttctttat cagtcagtca ggtgacttta tcaaaacaca ggaatttagt catgctccgg
    13261 ggcaagaaga ccgtctcatg accaatgaaa ccattgattg ggataagaaa gttgcaccaa
    13321 gtgctatcta cgaagaaggt gcagtggtct ttccagtcct tcacgggcca atgggagaag
    13381 atggctctgt tcaaggattc ttggaagttt tgaaaatgcc ttacgttggt tgcaacattt
    13441 tgtcatcaag tcttgccatg gataaaatca cgactaagcg tgttctggaa tctgctggta
    13501 ttgcccaagt tccttatgtg gctatcgttg aaggcgatga tgtgactgct aaaatcgctg
    13561 aagtggaaga aaaattggct tatccagtct tcgctaagcc gtcaaacatg gggtctagtg
    13621 tcggtatttc taagtctgaa aaccaagaag aactccgtca agccttaaaa cttgccttcc
    13681 gatatgacag ccgtgtcttg gttgagcaag gagtgaatgc ccgtgaaatt gaggttggcc
    13741 tcttgggtaa ctacgatgtc aagagcacgc tacctggaga agttgtcaag gacgttgcct
    13801 tttatgacta cgatgccaag tatattgata acaagattac tatggatatt cctgccaaaa
    13861 tcagtgatga tgtggtggct gtcatgcgtc aaaatgcaga aacagccttc cgtgccattg
    13921 gtggccttgg tctatctcgt tgcgatttct tctatacaga taagggagag atttttctca
    13981 acgagctcaa taccatgcca ggtttcaccc agtggtctat gtacccacta ctttgggaca
    14041 atatggggat cagctaccca gaactaatcg agcgtttggt tgaccttgcc aaggaaagtt
    14101 ttgacaagcg cgaagcgcat ttgatataaa atgaaagaga gggtagaagc cagaaccatc
    14161 actgcaaggt gactagagtt ctcggacttc gccccttttt aaaggagtag aaatgaaatt
    14221 aacaatctat gaagttgccc aagctgttgg agctaaaaat gatgttagtc tttttgcgga
    14281 cgcccagtta gaaaaggctg agtttgacag tcgattgatt gggactggag atttatttgt
    14341 gccacttaaa ggtgcgcttg atggccatga ctttattgaa acagcctttg aaaatggtgc
    14401 agcagtaacc ttgtctgaga aagaggtctc aaatcatcct tacattctag tagatgatgt
    14461 tttgacagcc tttcaatcct tagcatccta ctatcttgaa aaaacgactg ttgatgtctt
    14521 tgctgttaca ggttcaaatg gcaagacaac gactaaggat atgttggcgc atttactgtc
    14581 aacaagatac aagacctaca aaacacaagg caattacaat aatgagattg gccttcctta
    14641 cacagttctt catatgcctg aaggaacaga aaagttggtt ttggagatgg gacaggatca
    14701 cttgggagat attcatctct tgtctgaatt ggctcgtcca aaaacagcca tcgtgacctt
    14761 ggttggagaa gctcatttgg cctttttcaa agatcgttct gagattgcta aaggaaaaat
    14821 gcaaattgca gacggaatgg cttcaggttc cttgctttta acgccggctg accctatcgt
    14881 agaggactat ttgccaactg ataaaaaggt ggtccgtttt gggcaagggg cagagttgga
    14941 aatcacagac ttggttgagc gtaaggacag tctgaccttt aaggctaatt tcttggaaca
    15001 agcccttgat ttgccagtga ctggtaagta caatgctacc aatgctatga ttgcgtccta
    15061 tgttgcccta caagaaggag tttcagagga gcaaattcat caggccttcc aaggtcttga
    15121 attgacgcgt aatcgtactg agtggaagaa agcagccaat ggagcagata tcctgtcaga
    15181 cgtatataat gccaatccaa ctgctatgaa gctgatttta gagactttct ctgccattcc
    15241 agccaatgaa ggtggcaaga aaattgcagt gttggcggat atgaaggagc ttggtgacca
    15301 gtctattcaa ctccataacc agataatttt gagcctttct ccagatgtgc ttgataccgt
    15361 tattttctat ggagaagaca ttgctgaatt agcccaactt gctagtcaaa tgttcccaat
    15421 cggacacgtt tattacttca agaaaacaga agaccaagac caatttgaag acctagttaa
    15481 gcaggtcaaa gaaagccttg gggctcatga ccaaatcctg ctcaaaggct ctaactctat
    15541 gaatctagcc aagttggtag aaagtttaga aaatgaagac aagtgatttt gtcaagtatt
    15601 tgcaaagaat gattgccatt acagatactg gcttaacctt tacaaaagat ccgtttgacc
    15661 gtgagcgcta cgaagacttg cgagactttt tatctgaaat gttgaatcaa gcatcagacc
    15721 ttgattccga agaagtggca gaagtcttga agccaacttc tgcttatgcg actccgttaa
    15781 tggacgtccg tgcttggatt gttgaggacg aaaagatttg tctggttagg ggacaaggag
    15841 aggatagttg ggctttgcca ggtggctttg gtgaggttgg ctattctcca acagaaaata
    15901 ttctcaagga aattgaagaa gaaaccggtt ttaaagccaa agttgaaaga ctgctagctg
    15961 tttttgatac caatcgtttc caactacaga gcaaacagta tacaaagttt gtttttggat
    16021 gtaagcttct cgatggacaa ttccaagaaa atcaagaaat tgctgacctt caattttttg
    16081 ccattgacca actgccgaac ttatctgaaa aacgcattac caaggagcaa atagagcttc
    16141 tttggcaggt ttatcaaggt catagggggc aatatcttga ctaagaagat gattatcgta
    16201 tttctaaatc catttttaac aactagcatg gtataataat atgcaggaaa attttgaatt
    16261 atgaggaaga ctagatgaat ttatgggata ttttctttac gactcaggca accgagccgc
    16321 ccaaatttga ccttttttgg tatgttagcc tatttacgct cttagcctta accttttata
    16381 cagcccatcg ctatcgtgaa aagaaggttt accaacgatt tttccaaatc ttgcagactg
    16441 ttcagttaat ccttctttat ggttggtact gggttaatca tatgccactg tcagaaagcc
    16501 taccctttta ccattgccgt atggctatgt ttgtggtact cttgcttcct ggtcagtcca
    16561 aatataaaca atactttgca ttattgggaa catttgggac attagcagcc tttgtttatc
    16621 cagtgccaga tgcttaccct tttccacata ttaccatttt atcctttatc tttggtcatt
    16681 tagcactctt ggggaactct ctagtttatc tattgagaca gtataatgcg cgattgctgg
    16741 atgtgaaggg aatttttctc atgacctttg ccctaaatgc cttgattttt gtggtcaatt
    16801 tggtgacagg tggcgattac ggatttttga caaaaccgcc attggttggg gatcacggtc
    16861 tagtagctaa ttatttactt gtttcaattg tgctggtagc tactatcagt ttgactaaga
    16921 aaatcttaga attcttttta gctcaagaag cagaaaaaat gattgcaaag gaagcttaac
    16981 acagagcttt cttttttgct cttagagagt ttttacaagc agcttataaa ataagaattt
    17041 ctgaatagac aaactcaaaa aatggctggg aaatttagga aaaaagcaag cacgattaaa
    17101 ttttttgtgt tataatattt tgtgaatagc tatgcctatg tttagctatg gaataatacg
    17161 aagtgcgaaa cttggaagat agagaggaag cgatgtaatg gctagagaag gcttttttac
    17221 aggtctagat attggaacaa gctctgtcaa ggtgcttgtg gccgagcaga gaaatggtga
    17281 attaaatgta attggcgtga gtaatgccaa aagtaaaggt gtaaaggatg gaattattgt
    17341 tgatattgat gcagcagcaa ctgctatcaa gtcagccatt tcccaagcgg aagaaaaggc
    17401 aggcatttcg attaaatcag tgaatgtcgg cttgcctggt aatcttttgc aggtagaacc
    17461 aactcagggg atgattccag taacatctga tactaaggaa attacggatc aagatgttga
    17521 aaatgttgtc aaatcagctt tgacaaagag tatgacacct gaccgtgaag tcattacctt
    17581 tattcctgaa gaatttattg tggatggttt ccaagggatt cgtgacccac gtggcatgat
    17641 gggggttcgc cttgaaatgc gtggtttgct ttatacagga cctcgtacta tcttgcacaa
    17701 tttgcgtaag acggttgagc gtgcaggtgt tcaggttgaa aatgttatca tttcaccact
    17761 agcaatggtt cagtctgttt tgaacgaagg ggaacgtgaa tttggtgcta cagtgattga
    17821 tatgggggca ggtcaaacga ctgtcgctac aatccgtaat caagaactcc agttcacaca
    17881 tattctccaa gaaggtggag attatgtaac taaagatatc tccaaggttt tgaaaacctc
    17941 tcgcaaatta gcggaaggct tgaaactgaa ttacggggaa gcctatccgc ctcttgcaag
    18001 caaagaaacc ttccaagtag aggttattgg agaagtagaa gcagtcgaag tgacggaagc
    18061 ctacttgtca gaaattattt ctgcacgaat caagcacatc cttgaacaaa tcaagcaaga
    18121 attagataga aggcgtctat tggacctccc tggtggtatt gtcttaatcg gtgggaatgc
    18181 cattttacca ggtatggttg agcttgctca ggaagtcttt ggcgtccgtg tcaagcttta
    18241 tgtcccaaat caagttggta tccgtaatcc agcctttgcg catgtgatta gtttatcaga
    18301 atttgcgggt caattaacag aagttaatct tttggctcag ggagcgataa aaggtgagaa
    18361 tgacttaagt catcagccaa ttagttttgg tgggatgctg caaaaaacag ctcagtttgt
    18421 acaatcaacg cctgttcaac cagctcctgc tccagaagta gagccggtgg cgcctacaga
    18481 accaatggcg gatttccaac aagcttcaca aaataaaccg aaattagcag atcgtttccg
    18541 tggcttgatc ggaagcatgt ttgacgaata aagaggaaaa ataaattatg acattttcat
    18601 ttgatacagc tgctgctcaa ggggcagtga ttaaagtaat tggtgtcggt ggaggtggtg
    18661 gcaatgccat caaccgtatg gtcgacgaag gtgttacagg cgtagaattt atcgcagcaa
    18721 acacagatgt acaagcattg agtagtacaa aagctgagac tgttattcag ttgggaccta
    18781 aattgactcg tggtttgggt gcaggaggtc aacctgaggt tggtcgtaaa gccgctgaag
    18841 aaagcgaaga aacactgacg gaagctatta gtggtgccga tatggtcttc atcactgctg
    18901 gtatgggagg aggctctgga actggagctg ctcctgttat tgctcgtatc gccaaagatt
    18961 taggtgcgct tacagttggt gttgtaacac gtccctttgg ttttgaagga agtaagcgtg
    19021 gacaatttgc tgtagaagga atcaatcaac ttcgtgagca tgtagacact ctattgatta
    19081 tctcaaacaa caatttgctt gaaattgttg ataagaaaac accgcttttg gaggctctta
    19141 gcgaagcgga taacgttctt cgtcaaggtg ttcaagggat taccgatttg attaccaatc
    19201 caggattgat taaccttgac tttgccgatg tgaaaacggt aatggcaaac aaagggaatg
    19261 ctcttatggg tattggtatc ggtagtggag aagaacgtgt ggtagaagcg gcacgtaagg
    19321 caatctattc accacttctt gaaacaacta ttgacggtgc tgaggatgtt atcgtcaacg
    19381 ttactggtgg tcttgactta accttgattg aggcagaaga ggcttcacaa attgtgaacc
    19441 aggcagcagg tcaaggagtg aacatctggc tcggtacttc aattgatgaa agtatgcgtg
    19501 atgaaattcg tgtaacagtt gttgcaacgg gtgttcgtca agaccgcgta gaaaaggttg
    19561 tggctccaca agctagatct gctactaact accgtgagac agtgaaacca gctcattcac
    19621 atggttttga tcgtcatttt gatatggcag aaacagttga attgccaaaa caaaatccac
    19681 gtcgtttgga accaactcag gcatctgctt ttggtgattg ggatcttcgc cgtgaatcga
    19741 ttgttcgtac aacagattca gtcgtttctc cagtcgagcg ctttgaagcc ccaatttcac
    19801 aagatgaaga tgaattggat acacctccat ttttcaaaaa tcgttaagta aatgaatgta
    19861 aaagaaaata cagaacttgt ttttcgagaa gttggagagg ctagtctgag tgctcatcga
    19921 gagagtagtt cggtctctgt cattgcagtt accaagtatg tagatgtacc gacagcggaa
    19981 gccttgcttc cgctaggtgt tcatcatatc ggtgaaaatc gtgtagataa gtttctggaa
    20041 aaatatgaag ctttaaaaga tcgagatgtg acttggcatt tgattggtac cttgcaaaga
    20101 cgtaaggtga aagatgtcat tcaatacgtt gattatttcc atgcattgga ctcagtaaag
    20161 ctagcagggg aaattcaaaa aagaagtgac cgagtcatca agtgtttcct tcaagtaaat
    20221 atttctaaag aagaaagcaa acacggtttt tcgagagagg aactgctgga aatcttgcca
    20281 gagttagcca gactagataa gattgaatat gttggtttaa tgacgatggc accttttgag
    20341 gctagcagtg agcagttgaa agagattttc aaggcgaccc aagatttaca aagagaaatt
    20401 caagagaaac aaattccaaa tatgcctatg accgagttaa gtatgggaat gagtcgtgat
    20461 tataaagaag cgattcaatt cggttccact tttgttcgta taggtacatc attttttaag
    20521 taggagagaa ccatgtcttt aaaagataga ttcgatagat ttatagatta ttttacggag
    20581 gatgaggatt caagtctccc ttatgaaaaa agagatgagc ctgtgtttac tccagtaaat
    20641 tcttcacagg aaccggctct cccaatgaat caaccttcac agtcggttgg tacaaaagag
    20701 aacaatatca ccagacttca tgcaagacaa caggaattgg caaatcagag tcagcgtgca
    20761 acggataagg tcattataga tgttcgttat cctagaaaat atgaggatgc aacagaaatt
    20821 gttgatttat tggcaggaaa cgaaagtatc ttgattgatt ttcagtatat gacagaggtg
    20881 caggctcgtc gttgtttgga ctatttggat ggagcttgtc atgttttagc tggaaatttg
    20941 aaaaaggtag cttctaccat gtatttgttg acaccagtga atgttattgt aaatgttgaa
    21001 gatatccgtt taccagatga agatcaacag ggtgagttcg gttttgatat gaagcgaaat
    21061 agagtacgat aatgattttt ttaattcgta tgatttataa tgcagtggat atttactccc
    21121 tgattttggt agccttcgct gtcatgtctt ggtttccagg tgcctacgaa tccagtttag
    21181 gtcgttggat tgtagcgttg gtgaaaccag tacttgctcc cttgcaacgc ctgcctttac
    21241 agatagcggg tcttgattta tctgtttggg tcgcgattgt tttggttcga tttttaggag
    21301 aaaacctagt gcgttttctg gcgatgatag gatgaataaa gggatttatc agcatttctc
    21361 catagaagat cgtccatttc ttgacaaggg aatggaatgg ataaagaagg tagaagatag
    21421 ctatgctcct tttttaactc cttttatcaa tcctcatcag gagaagctat taaagatttt
    21481 ggccaaaacc tatggtcttg cttgtagcag tagtggggaa ttcgtctcga gtgagtatgt
    21541 tcgagtttta ttatacccag attatttcca accagagttt tcagattttg aaatatctct
    21601 ccaagaaatt gtgtattcca ataaatttga acatttaacg catgctaaga ttttagggac
    21661 agtcatcaat caattaggga ttgaacggaa actttttgga gatatcctag tagatgaaga
    21721 acgggcgcag attatgatta atcagcagtt tcttcttctc tttcaagatg gactaaagaa
    21781 aattggtcgt atacctgttt cgttggagga acgtcctttc accgagaaaa tagataagct
    21841 agaacagtat cgagaactga atttatctgt gtctagtttt cgattagatg ttcttttatc
    21901 aaatgttttg aaactatcta ggaatcaagc aaaccagttg attgaaaaga aacttgtcca
    21961 agtaaattat catgtggtag acaaatcaga ttacactgtt caagttggag acttgattag
    22021 tgtgagaaaa tttggtcgct tgagattatt tcaagataag ggacaaacga aaaaagagaa
    22081 gaaaaaaata accgtccagt tattattaag taagtgagga atagaatgcc aattacatca
    22141 ttagaaataa aggacaagac ctttggaact cgattcagag gttttgatcc agaagaagtc
    22201 gatgaatttt tagatattgt ggttcgtgat tacgaagatc ttgtgcgtgc gaatcatgat
    22261 aaaaatttgc gtattaagag tttagaagag cgtttgtctt actttgatga aataaaagat
    22321 tcattgagcc agtctgtatt gattgcccag gatacagctg agagagtgaa acaggcggcg
    22381 catgaacgtt caaacaatat cattcatcaa gcagagcaag atgcgcaacg cttgttggaa
    22441 gaagctaaat ataaggcaaa cgagattctt cgtcaagcaa ctgataatgc taagaaagtc
    22501 gctgttgaaa cagaagaatt gaagaacaag agccgtgtct tccaccaacg tctcaaatct
    22561 acaattgaga gtcagttggc tattgttgaa tcttcagatt gggaagatat tctccgtcca
    22621 acagctactt atcttcaaac tagtgatgaa gcctttaaag aagtggttag cgaagtactt
    22681 ggagaaccga ttccagctcc aattgaagaa gaaccaattg atatgacacg tcagttctct
    22741 caagcagaaa tggaagaatt acaagctcgt attgaggtag ccgataaaga attgtctgaa
    22801 tttgaagctc agattaaaca ggaagtggaa actccaactc ctgtagtgag tcctcaagtt
    22861 gaagaagagc ctctgctcat ccagttggcc caatgtatga agaaccagaa gtagctccag
    22921 tgcatccgac aggtccaaca ccagctacag aaactgttga ttcagcatca ggatttgaag
    22981 caccgcaaga atccgttaca attttataag aaacgatgtg agaacaatat cttatcctta
    23041 tatttccagc gagcaggaga tggtgtgagt cctgcattcc ctaacgataa gattatcctc
    23101 tcaaaaactc aagtctgaag ctagtaagat ttgacgtttc ccacgttacg ggataagagg
    23161 gagaaagact aaatcttttt ccgaataaag gtggtaccac gattttcgtc ctttttggaa
    23221 gtcgtggttt ttaatttgtt attatttata aaggagatac catgaaactc aaagataccc
    23281 ttaatcttgg gaaaacagct ttcccaatgc gtgcaggcct tccgaccaaa gagccagttt
    23341 ggcaaaagga atgggaagat gcaaaacttt accaacgtcg tcaagaacta aatgaaggga
    23401 aaccgcattt tgtcttgcat gatggccctc catacgcaaa cggaaatatc cacgttggac
    23461 atgccatgaa tcatatctca aaagatatca tcattcgttc taagtctatg tcaggtttta
    23521 acgcacctta tatcccaggt tgggatactc atggtctgcc aatcgagcaa gttttggcaa
    23581 agcaaggtgt gaagcgcaaa gaaatggact tggttgagta cttgaaactc tgtcgtgagt
    23641 acgctctttc tcaagtttat aaacaacgtg atgatttcaa acgcttgggg atgtcaggtg
    23701 actgggaaaa tttatatgtg actttaactc cagactatga agcagcccaa atccgtgtct
    23761 ttggtgagat ggctaataag ggttatatct accgtggtgc caagccagtt tactggtcat
    23821 ggtcatctga gtcagccctt gccgaagcgg aaattgaata ccatgatttg gtttcgactt
    23881 cactttatta tgccaataag gtaaaagatg gcaaaggtat cctagataca gatacttata
    23941 tcgtagtctg gacaacaact ccatttacca tcacagcttc tcgtggtttg actgttggtg
    24001 cagatattga ttacgttttg gttcaacctg ctagtgaaac tcgtaagttt gtcgttgctg
    24061 cagaattgtt gactagcttg tctgagaaat ttggctgggc tgatgttcaa gtgttggcaa
    24121 cttaccgtgg tcaagaactc aaccacatcg taacagaaca cccatgggat acagctgtag
    24181 atgagttggt aatccttggt gatcacgtta ccactgactc tggtacaggt atcgtccata
    24241 cagcccctgg ttttggtgag gacgactaca atgttggtat tgctaatggt cttgaagtcg
    24301 cagtgactgt tgacgaacgc ggtatcatga tggcgaatgc tggtcctgag tttgaaggtc
    24361 agttctacga caaggttgta ccaactgtta ttgaaaaact tggtaacctc cttctagccc
    24421 aagaagaaat ctctcactca tacccatttg actggcgtac taagaaacca atcatctggc
    24481 gtgcagttcc acaatggttt gcctcagttt caaaattccg ccaagaaatc ttggatgcta
    24541 ttgataaagt taaattccat acagaatggg gtaaagtacg tctatataat atgattcgtg
    24601 accgtggtga ctgggttatc tctcgtcaac gtgcttgggg tgttccactt ccaatcttct
    24661 atgcagaaga cggtacagct atcatgacag ctgagactat tgaacatgtg gcgcaactct
    24721 ttgaagtaca tggttcaagc atttggtggg aacgtgatgc caaaaacctc ttaccagaag
    24781 gatttacaca tccaggttct ccaaatgggg agttcaagaa agaaacagat attatggatg
    24841 tatggtttga ctcaggttca tcatggaatg gtgttttggt aaatcgtcca aatctgactt
    24901 atccagctga cctttacctt gaaggttctg accaataccg tggttggttc aactcatcac
    24961 ttattacatc tgttgccaac catggcgtag caccttacaa acaaatcttg tcacaaggtt
    25021 ttacccttga tggtaaaggt gagaagatgt ctaaatcact tggaaatacc attgctccaa
    25081 gtgatgttga aaaacaattt ggtgcagaaa tcttgcgtct ctgggtaaca agtgttgact
    25141 caagcaatga cgtgcgtatc tctatggata ttttgagcca agtttctgaa acttaccgta
    25201 agattcgtaa cactcttcgt ttcttgattg ccaatacatc tgactttaac ccagctcaag
    25261 atgtagtcgc ttacgatgaa cttcgttcag ttgataagta catgactatt cgctttaacc
    25321 agcttgtcaa gaccattcgt gatgcctatg cggactttga attcttgaca atctacaagg
    25381 ccttggtgaa ctttatcaac gttgacttgt cagccttcta ccttgatttt gccaaagatg
    25441 ttgtttacat tgaaggtgcc aaatcattgg aacgccgtca aatgcagact gttttctatg
    25501 acattcttgt caaaatcacc aaactcttga caccaatcct tcctcacact gcggaagaaa
    25561 tctggtcata tcttgagttt gaagctgaag acttcgttca attgtcagaa ttgccagaag
    25621 ctcaaacttt tgctaatcaa gaagaagtct tggatacatg ggcagccttc atggacttcc
    25681 gtggacaagc tcaaaaagcc ttggaagaag ctcgtaatgc aaaagttatc gggaaatcgc
    25741 ttgaagcaca cttgacagtt tatccaaatg aagttgtgaa aactctactc gaagcagtaa
    25801 acagcaatgt ggctcaactt ttgatcgtgt cagacttgac catcgcagaa gggccagctc
    25861 cagaagctgc tgttagcttc gaagatgtag ccttcacagt tgaacgcgct gcaggtcaag
    25921 tatgtgaccg ttgccgtcgt atcgacccaa caacagcaga acgcagctac caggcagtca
    25981 tctgtgacca ctgtgcaagc atcgtagaag aaaactttgc ggaagcagtc gcagaaggat
    26041 ttgaagagaa ataaggttga aaagtctagg caaaattcaa tttgagaaga aaagacaact
    26101 aattttatag tctattaaac gcattgtatc acgtttttga atacctgata tgatgcgttt
    26161 tttatttatt ttaaaaattt gcgaggtatg actttttata ctcaacaaga atcaaagaga
    26221 aacttagcaa gctaacagta gtaagataaa ataggaattt gatattaggg ataagattgc
    26281 taaatagtgt aatattttta caataataaa tttatatagt tatttttggt ttctgaaaag
    26341 tattatattt tatttcatat tatacaaatt tttattttat aatatcagaa aatacttttt
    26401 ttaaaagcaa atatgataca attttatttg aaaaaaataa aaaaggagat tttattatga
    26461 aattaaaaac acttgcttta attagtggta tcgtcggtct tgtgggagga attttacttc
    26521 ttattggtcc ttttgtcttg ttgggaacag cggtaaacac agttgctaca actcttaatg
    26581 gaggagctac tgcaggggct ttttcaggtg ttgccttact cttgaatgcc ttgaagattg
    26641 caaatcttgt tcttggtatc attgctattg tttactataa aggagataat cgtgtaggtg
    26701 cagctccgtc tgtactaatg attgtttttg gtggagttag tctcattcca ttcttaggat
    26761 gggttggggg gattcttgtt attatcggag gatctctatt ccttgcaaca ttgaagaaat
    26821 tcaaatcaga agaataaaag gtattttagc atgaaaagaa caaaaaagtt tatcggtata
    26881 ggagtagctc tattatctct ttttcttcta gttgcatgtg gaacataaag ttcaaaggat
    26941 acttcaacaa gtaatgatga gaagacagta gcaacatcca atagttcaaa agaaacaatc
    27001 actttcgata caccggttgt aacagacgat gtgattgaat caatacgcac ttatgcagat
    27061 tatatagatc tttataaaaa tatttttgat gattatttta ctaaagctga ggaaggtttc
    27121 aaaggcacag ctatggaaaa taatgactcg tttactaaac taaaagagtc aactcaaaaa
    27181 ttattcgatg cgcagaaaaa aaggttaaat aatgaagata gaatagaaac aactaaaaac
    27241 aatgtgattg ccaaacattg tcaaacagtc ctttcctttt tggttttgac tagctttttt
    27301 gtgaaaaatt gtgtaaaata gaatagataa acgaggggaa acctcggaaa atttaaagga
    27361 gaatccatct aatggtaaaa ttggtttttg ctcgccacgg tgagtctgaa tggaacaaag
    27421 ctaacctttt cactggttgg gctgatgttg atttgtctga aaaaggtaca caacaagcga
    27481 ttgacgctgg taaattgatc aaagaagctg gtatcaaatt tgaccaagct tacacttcag
    27541 tattgaaacg tgctatcaaa acaactaact tggctcttga agcttctgac caattgtggg
    27601 ttccagttga aaaatcatgg cgcttgaacg aacgtcacta cggtggtttg actggtaaaa
    27661 ataaagctga agctgctgaa caatttggtg atgagcaagt tcacatctgg cgtcgttcat
    27721 acgatgtatt gcctccaaat atggaccgtg atgatgagca ctcagctcac acagaccgtc
    27781 gttatgcttc acttgacgac tcagtaatcc cagatgctga aaacttgaaa gtgactttgg
    27841 aacgtgctct tccattctgg gaagataaaa tcgctccagc tcttaaagat ggtaaaaacg
    27901 tattcgtagg agctcacggt aactcaatcc gtgcccttgt aaaacacatc aaaggtttgt
    27961 cagatgacga gatcatggac gtggaaatcc ctaacttccc accattggta ttcgaattcg
    28021 acgaaaaatt gaacgtcgtt tctgaatact accttggaaa ataaaaaatt gtaagtctag
    28081 aattgatttc taggcttttt atgttagtat ggaagtatga taaggaataa aaaacaagat
    28141 tatgtactgg cctacaagca accagtttca accacttaca tgggttggga agaagaagct
    28201 ttaccgatag gcaatggttc tttaggagca aaagtatttg gccttatagg ggctgaacgg
    28261 attcaattta atgaaaaaag tctctggtct ggaggtccac ttcctgatag ttcagattat
    28321 cagggtggaa atcttcagga tcagtatgtt tttttagctg agattcggca ggctttggag
    28381 aagagagatt acaatctggc taaggaactg gctgagcagc acctaattgg gccaaaaacg
    28441 agtcaatatg ggacctatct gtcttttggg gatattcaca ttgagttcag ccagcaaggt
    28501 acgactttgt ctcaggtgac ggactatcag agacagctga atattagtaa ggcacttgtg
    28561 acgacttctt atgtctataa gggaacgcga tttgaacgtg aagcttttgc gagttttcca
    28621 gatgatctct tggttcagcg ttttactaag gaaggggcgg aaactctaga ttttactata
    28681 gaactatcct tgacctgtga tttggcttct gatggaaagt atgagcagga aaaatctgat
    28741 tacaaggagt gtaagttgga tattactgat tctcatatct tgatgaaggg aagagttaag
    28801 gataatgatc tgcggtttgc tagttatcta gcttgggaaa cggatggaga tattagagtt
    28861 tggtcagata gggttcagat atcaggagcc agttatgcca atctcttctt ggccgctaag
    28921 acggattttg cccaaaatcc tgctagcaat tatcgcaaga aactagattt agagcaacag
    28981 gtgatagact tggtggacac agctaaagaa aagggctata cccaattgaa atcaaggcat
    29041 atcgaggact accaagcctt attccagcgt gttcaattgg atttggaagc taatgttgac
    29101 gcattcacta cagatgattt gttaaaaaat tataagccac aagaagggca ggctttggag
    29161 gagctgttct tccagtatgg acggtattta ttgattagtt cgtccagaga ctgcccagat
    29221 gctctaccag ctaacctaca gggagtctgg aatgcggtcg acaatcctcc ttggaattcg
    29281 gactatcact taaatgtcaa tctgcagatg aattattggc cagcctatgt taccaatctc
    29341 ctagaggcgg tctttccggt catcaactat gtagatgatt tgcgtgtcta tggtcgtcta
    29401 gcggctgtaa agtatgcagg aatcgtctct caaaaaggtg aggaaaatgg ttggttggtt
    29461 catactcaag cgactccctt tggttggacg gcacctggtt gggattacta ttggggttgg
    29521 tcaccagctg ccaatgcgtg gatgatgcaa accgtttatg aagcctattc attttatagg
    29581 gaccaagact atctcaggga gaaaatttat cccatgttga gggaaacggt tcgtttttgg
    29641 aatgcctttt tacataagga tcagcaggcg cagcgttggg tgtcttctcc gtcttattcc
    29701 ccagaacatg ggccgatttc gattggcaat acttatgacc aatctctgat ttggcagtta
    29761 tttcatgatt ttattcaggc tgctcaggaa ttgggactgg atgaggactt gttgactgag
    29821 gttaaggaga agtctgattt actaaatcct ttgcaaatca ctcaatctgg tcgaatcagg
    29881 gagtggtatg aggaggaaga gcagtatttt caaaatgaga aagtggaggc ccagcatcgg
    29941 cacgcttccc atctagtggg actctatcct ggcaatctct ttagctacaa gggacaagag
    30001 tatattgaag cggcacgtgc tagcctcaat gatcgtggag atggcggcac aggctggtcc
    30061 aaggctaata agatcaatct ctgggcgcgt ttgggagatg gcaatcgagc ccataaatta
    30121 ttggcagagc agttaaaaac atccaccttg ccaaatcttt ggtgtagcca tcctcctttt
    30181 cagatagatg gtaattttgg tgctactagt ggcatggcag aaatgttact ccagtctcat
    30241 gcagcttatc tggtacctct agctgcccta cctgatgctt ggtcaacagg ttctgtttca
    30301 ggcttaatgg cacgtggaca ttttgaagtg agcatgagct gggaagataa aaaactctta
    30361 cagttgacca ttttatcaag gagtggagga gatttgcgag tttcttatcc agatattgag
    30421 aagagtgtga ttaaaatgaa tcaagaaaaa ataaaagcga aatgcatggg gaaagattgt
    30481 atttcggtgg caacagcaga aggtgatctt gttcaatttt atttttaaga agatgttata
    30541 aggcagtaat ttgaaacttc cttttaataa ggatttaaga atataggcag tttccaacta
    30601 gttgaaaaag cgttataatg ataataggaa gtaatactca atgaaaatca aagagcacaa
    30661 actaggaagc tagccgcagg ttgctcaaaa cagtgttttg aggttgtaga tggaagctga
    30721 cgtggtttga agagagattt tcgaggagta taatttgttt gatagagggt gggtctgatg
    30781 gcttatattg agatgaaaca ctgttacaag cgttatcagg ttggggacac ggagattgtg
    30841 gccaatcgtg atgtgaattt tgagattgaa aagggggagc tggttattat ccttggtgct
    30901 tcaggtgcag gcaagtcaac agttcttaac cttcttgggg gaatggatac caatgatgaa
    30961 ggggaaatct ggattgatgg tgttaatatt gcggattata gttcccacca gcgcaccaat
    31021 taccgtagaa atgatgtggg gtttgttttt cagttttata atctagtttc taatctgaca
    31081 gctaaggaaa atgtggaact ggcttctgaa attgtgacag atgccttgaa tcctgatcag
    31141 gtcttgacag atgtaggtct ggctcatcgt ctcaataact ttccagccca gctttctgga
    31201 ggggagcaac agcgagtctc cattgcacgc gcggtagcca aaaatcctaa aattctcctt
    31261 tgtgatgaac cgactggagc cttggattat cagacgggca agcaggtttt gaaaattctc
    31321 caagacatgt ctcgtcaaaa gggagcgacg gtgatcatcg tgactcataa tggagctttg
    31381 gcgcccattg ctgatcgcgt gattcatatg cacgatgcca gtgtcaagga tgtggtgctc
    31441 aaccagcatc ctcaggatat tgacagtttg gagtactagc atgatcaagc gaaaaactta
    31501 ttggaaggac ttaattcagt ccttcacaga ctccaagggg cgttttttat ccatcttgat
    31561 cctgatgatg ttgggatctc tagccttagt aggcctcaaa gtaaccagtc ccaacatgga
    31621 ggcgacagct aatgcttatt taacaactgc tcaaaccttg gatttggcag tcatgtctaa
    31681 ctatggcttg gatcaagcag accaagaaga actaaaacag acggagggcg cagaggtcga
    31741 gtttggctat ttgacagatg tgactatgga taatgggcag gatgccattc ggctgtactc
    31801 caaaccagag cgaatttcaa cctttcagct aagaaaggga cgacttcctc agtcagacag
    31861 ggaaatcgct ttggccactc atttgcaagg ccaatacagc gtgggacagg agattagttt
    31921 taaagaaaaa gaagagggtc attcctcttt aaaagaccat acttatacca ttactggttt
    31981 tgtggattcg gctgaaatcc tctcccagcg agatatgggc tacgcaggaa gtggaagtgg
    32041 gactctgaca gcctatgggg tgattttacc tagtcaattt gatcagaaag tctacaatat
    32101 agctcgtttg aaatatcaag atttagcagg tttaaatgcc ttttcatcag cttatgaaga
    32161 aaaatccaag caacatcagg aagaccttga acaaacttta tcagataatg gcaaggtacg
    32221 tctgcaactt ttgaaaaaag aaggacaaga gtctctagac aaggggcaag agactcttga
    32281 caaggctcag actaatttgc aggaaggcaa gcgtcgttta gcagctgctc aagctcgtat
    32341 acaggctcaa gaaagtcaac tagccttgtt tcctcaagct cagagagagc aggctagtgc
    32401 tcaacttacc caagccaagc aggaactggg caaggaagag gacaaactaa agcaagctga
    32461 acaaaatcta gcccaagaaa aggaaaaatt agaaaaacat cagcaagtct tggatgattt
    32521 ggcggagcca aggtatcagg tttataatcg tcagaccatg ccaggtggtc agggctatct
    32581 tatgtatagc aatgcttcat ccagtattcg agcagtgggc aatatctttc ctgtggtact
    32641 ttatgccgta gcagccatgg tgacctttac gaccatgact cgctttgtag acgaagagcg
    32701 aactcatgca gggattttta aggccttggg ttatcgtagt aaggatatta tcgccaagtt
    32761 tctcctttat ggactagtag ctgggactgt cggaacggct ctaggtagta tacttggtca
    32821 ttatttgcta gccagtgtaa tttcaagtgt cattacaaaa ggcatggtgg tgggagaaac
    32881 ccagattcag ttctattgga cctatagctt actagctctt gtcttgagct ggttggcgag
    32941 tgtgttacca gcctatctgg tggcttggag ggaacttcat gacgaagcag cccagcttct
    33001 acttcctaaa cctcctgtca aaggagctaa aatcttattg gagcgtatcg gttttatctg
    33061 gcgtcgtctc agttttactc ataaggtaac agcccgcaac atctttcgtt ataagcagag
    33121 aatgttgatg acaatctttg gtgtggcagg ttctgtagct ctgctctttg caggtttggg
    33181 aatccaatct tctgtagcag gagttccgtc taaacagttt caacaaatcc aacagtatca
    33241 gatgcttgtc tctgaaaatc ctagtgcgac caatcaggac aaggtagagc tagcagaagt
    33301 gttgaaaggg caggagatac tagcctacca gaaaatctat tctaaaacgc tagacaagga
    33361 tttcaagggc agggctggtc ttcaaaacat tactcttatg atgatagaga aggaagattt
    33421 gactcccttt atccatcttc aacatcatca gcaggagctg acattaaaag atggcatcgt
    33481 tattacagct aaactcgccc agctggcagg tgtcaaggtt gggcagactt tagaaattga
    33541 aggtaaggaa ctaaaggtcg ctgctattac tgagaactac gttggtcact ttatttatat
    33601 gagtcaggct agctatgagc aactttacgg acagctaccc caagccaaca cttatctggt
    33661 ctcattaagg gataccagtg caactagtat cgaaagtcag gcgggcttgc ttatgaatca
    33721 atctgcggtg tccagtgttg tccaaaatgc ttcagccatt cgactcttcg actctatcgc
    33781 tagctcactc aatcagacca tgaccatctt ggtcatcgta tcggttctat tagctattgt
    33841 catcctttac aatctgacca atatcaacgt agctgagaga atccgtgaac tctccactat
    33901 caaggttctc ggttttcata ataatgaagt caccctctac atttaccgtg agacgattgt
    33961 gctgtccctt gtgggaatcg tacttggtct ggtagctggt ttctatttac accaattttt
    34021 gattcaaatg atttcgcctg cgactattct cttttatccg caggtaggct gggaagtcta
    34081 tgtaatccca gtggcagcag taagcatcat tttgaccttg cttggtttct tcgtcaatta
    34141 ttatctgaga aaggttgaca tgttagaagc cctgaaatct gtagagtaag gtagttattt
    34201 ttagctgatt gaacttctat ttactaatat tcaaaaatcc tccgtttcaa agagcaggga
    34261 actctttgtg acagaggatt ttttctatag ggctttagca gctgcaattg cggcttcgaa
    34321 gtttggctca gaattgatat tatccacgta ttcaacgtag cgaatcgtat tgtcagtatc
    34381 gaggacaaag actgcgcgtg ctaataggtg ccattcgttg atcaagaggg cataatcgcg
    34441 tccgaaagaa tggtcaaagt agtctgaaag cataatggca ttgtcaaggc cttcagcacc
    34501 gcaccaacgt ttttgagcaa aaggtaggtc cattgaaaca gtcaatacga ccgtgttgtc
    34561 cagtccagcc aattcttcat taaaacgacg tgtttgagtt gagcagatgc ctgtatcgat
    34621 agaaggaacg acactcaaga cttttttctt gccatcaaaa tcagccagag attttttaga
    34681 aagatctgtt gtagtaagag aaaaatcaag cgccttgtcg ccgacttgta gttgtttacc
    34741 tgtaaagctc acaggatttc cgagaaaagt taccatagga tactccaatc ttttttcttc
    34801 cattgtatct gaaacagtca gaattttcca atgatttgac cggaaatgtg tgcatagaaa
    34861 aaacgccagc tcacatgaga atgacgtttt tcagaggctt attttgccaa tccttcagca
    34921 atcttgtcaa ggttgtattt catcatgctg tagtagctgt cgccttcttt accttgttct
    34981 gcgatagagt cagtaaagat ttgtgcgtag attgggatgt ttgtgtcttg agaaacagtt
    35041 ttcattggac ggtcatccac acttgattct acaaagagtg atggaacttt tgtttggcga
    35101 agtttttcaa ccaaggtctt gatttgttca ggagttcctt cttcttcagt attgatttcc
    35161 cagatgtagg cacttgggac accataggct ttagagaagt atttgaatgc tccttcgctg
    35221 gttacaatga gtttcttttc agcagggatc ttattaaatt tatccttact ttctttatca
    35281 agtttgtcta acttatcagt atattctttg agattttttt catagaattc tttattgtta
    35341 gggtctttgg cgctcaattg tttggcgata tttttagcaa aaataatacc gttttcaagg
    35401 ttaagccaag cgtgtgggtc ttcttttcct ttttcatttt gaccttcaag gtagataaca
    35461 tcaacgccgt cgctgactgc gaagtagtct ttgttttcag ttttcttggc attttctacc
    35521 aattttgtaa accaagcatt gccacctgtt tcaaggttga taccgttata gaaaatcaaa
    35581 tcagcctcag aagttttctt aacgtcttca ggaagtggtt cgtattcgtg tgggttttgc
    35641 ccaatcggaa cgatactatg aaggtcaatt ttgtcaccag caatattttt agtaatatca
    35701 gcgatgattg agtttgtagc aacaactttt agtttttgac cagaagttgt atcttttttt
    35761 ccgctagcac atgctacaag aatgattgca gaaagaaaga gaacgagtaa tgtacctaat
    35821 tttttcatta gatcctccaa tttattaggg ctttgcccct tattttaaca aatgtttatt
    35881 tttcagtttc aaatatcgtt gtttgggagc gataaagaag ctaatgagaa agaaactagc
    35941 agctgtaagc acgatactag aacctgccgc aacattaaaa ctatagccaa taaagagtcc
    36001 caaaactgaa gcagtagctc cgaaggttga ggaaaggaaa atcatgcttt tcagactatt
    36061 agcatacaga taagcagttg cagctggggt aatcagcatg gctacaatca ggatagttcc
    36121 gacactttgc atggctgtca cagacacgag agtcaggagt accatgagaa ggtagtgata
    36181 gaaattgaca ggcattccca tggctttagc caagagttca tcaaaggaag ttatcaagag
    36241 ttgcttgaag aaaatccaga ttaacaagag gatggctgcc cccacaccca tagtaataaa
    36301 catatccgta tcttggacgg ccagaatatt accaaaaagg atatggaaaa ggtcagttga
    36361 acttttagcg acaccaatca agatgatacc gagggctaag aaagaagaaa aggtaatgcc
    36421 gatggcggta tcgcttttga taatcgagtt tcctttgatg taggtaatga tgatggcagc
    36481 tagcaatcca aagacaatgg ctccgataaa gaagtcaagg cccaagatga aggagagggc
    36541 tacacctggt aagacagcat gtgaaatggc atctcccatg agtgacatcc cgcgtagaat
    36601 aatgaaacat cccacggctc cagctacaat cccgacgaca atagctgtta tcaaggcatt
    36661 ttgtaggaaa tggaattttt gcaatccatc gataaattct gcaatcatag gtcacctcca
    36721 ttgaaaaaga gttgattacc gtaagcttct tttagattgg tttcggtaaa agtttctttt
    36781 gttggaccaa aggcaatcac ttctcgattg acaagtaaga cttgatcgaa gtagtgggga
    36841 atcttgctga ggtcgtggtg aacgatgaga accgtcttcc cagctttttt caaatctctc
    36901 agcgtattca tgatgatttc ctcactgaca gagtcaatcc cagcaaaggg ttcatccaag
    36961 aggatatagt cggcttcctg caccaaacat ctggcaatca agacccgctg gaattgacct
    37021 ccagacagtt gactaatttg acgttcagcg tagtcagcta ggccgacgat ttcaagggcc
    37081 tcttgcactt tcttccaatg tttagccttt aaacttcgaa agagaggaat agagggaaat
    37141 agtcctaacg agacgcattc cttgaccttg atgggaaagt tgtagtcgat attgattttt
    37201 tgttcgacat aggcaattcg gtgtaaggat tttttaactt ccttgtcatc gagaaatgcc
    37261 tgaccttgat gtgggataat tcccagcata ccttttaata gtgttgattt cccagcgccg
    37321 tttggaccaa tgatgccagt aattgttggt ccatggagca ctagtgaaat atccttaagt
    37381 gccaacgttt ctttgtagga gacactgagg ttttcgatac gtatcataaa cttgtattcc
    37441 tcctgtctct taatatacat taaaaaaaaa attaagtcaa gttaattttt gaaaaaatta
    37501 aaataataac tgaaaaatag attctaaaga taactttcag gataaatttc taaattataa
    37561 aacgcatagt atcaagtgta aaaaacttgg aattatgcgt tttatcatgg aaagattttt
    37621 tataatagct aaaaaataat agttaaatgg ttattaattg cattccctag tgatttttgt
    37681 taagataaat gcaaatacaa atgaaagcga gaacaagatg acacgttatc aagatgattt
    37741 ttatgatgct atcaatggag aatggcaaca gacagctgaa atcccagcag ataagtctca
    37801 aacaggaggt tttgttgatt tagaccagga aattgaagac ctgatgctgg cgacaacaga
    37861 caagtggtta gcaggtgaag aagtgcctga ggatgctatc ttggaaaact ttgtcaaata
    37921 ccaccgccta gttcgtgatt ttgacaagag agaagctgac ggtatcacac ctgtcttacc
    37981 actccttaaa gaattccaag aattggaaac ttttgcggat tttacagcta aactagcaga
    38041 gtttgagctt gcaggaaaac caaacttcct tccttttggt gtatcgccag actttatgga
    38101 tgctagaatc aatgttctat gggctagcgc tccaagcaca atcttgccag atacgaccta
    38161 ctatgcagaa gaacatcctc agcgcgaaga gctcttgact ctttggaaag aaagcagcgc
    38221 aaatctcctc aaggcttatg atttctctga tgaagaaatt gaagacttgc tagaaaaaag
    38281 acttgaattg gaccgccgag ttgcggcagt ggtgctctct aatgaagaaa gttcagaata
    38341 tgctaaactc tatcatccat attcttacga agatttcaag aaattcgcgc ctgccctacc
    38401 tttggatgac ttcttcaaag cagttattgg gcaattacca gacaaggtta ttgtagacga
    38461 ggaacgtttc tggcaagcag cagagcaatt ttacagtgag gaagcctggt ctctccttaa
    38521 agcaaccttg attttgagtg ttgtcaatct ttcaaccagc tatttaacag aggatatccg
    38581 tgttttgtct ggtgcctaca gccgtgccct ttctggagtt ccagaggcaa aagataaggt
    38641 caaagcagct tatcatctag cacaggaacc tttcaagcaa gccctggggc tttggtacgc
    38701 ccgtgagaag ttctctccag aagccaaggc ggatgtggag aaaaaagtgg caaccatgat
    38761 tgatgtctat aaggagcgtc tgcttaagaa tgactggctc actccagaaa cctgtaaaca
    38821 ggctatcgtg aagctcaatg tgatcaaacc ttatattggc tatccagaag aattgcctgc
    38881 acgttacaag gataaggtag tgaatgaaac tgccagtctt tttgagaatg ctctagcctt
    38941 tgcgcgtgtg gaaatcaagc acagttggag taagtggaac cagcctgtag actataagga
    39001 atggggcatg cctgctcata tggtcaatgc ctactacaat cctcagaaga acctgattgt
    39061 ctttccagcg gccattttac aggcgccttt ctatgacttg catcagtcat cttctgctaa
    39121 ctacggtggt attggggcag tgattgccca tgaaatttcc cacgcctttg atactaacgg
    39181 ggcttccttt gacgaaaatg gtagcctcaa ggattggtgg acagagagcg actatgctgc
    39241 cttcaaggag aaaacacaaa aagtcattga ccaatttgat ggacaggatt cttatggagc
    39301 aaccattaac ggtaaattga ctgtatcaga aaacgtggct gacttgggag gaatcgcagc
    39361 agcgcttgaa gcagctaaga gagaagcaga cttctcagca gaagagttct tctacaactt
    39421 cggtcgcatc tggcgcatga aaggtcgacc agaatttatg aaacttttgg ctagcgtcga
    39481 tgtgcacgca ccagccaaac tccgtgtcaa tgtgcaagta ccaaacttcg acgatttctt
    39541 tacaacctat gatgtcaaag aaggagacgg aatgtggcgt tcaccagagg agcgcgtgat
    39601 tatttggtaa tacaaaaaat ctagtcatca gaaaaaaggc atccaatcac gtgtgaaaac
    39661 cttgatagga tgccttttgt aatagaaaga tttgctggat agtttactta aatttcgatt
    39721 gtcatcatct tgctagaaaa agggattgaa ggccttttcg tgagcgatag tagtagctgg
    39781 accatgtcct ggatagacat cgtagtttgg tagggtgaag agttgggtct ggatactatg
    39841 aaggagttgc tccatgctac cagtcggaag gtcggtccgt ccgatagttt cgcggaatag
    39901 agcatctccc gtcaagacta ggtgagcatc aggaaagact agggaaacac caccgataga
    39961 gtgccctggg gtcggtagaa ccttaaaacg aaattcctct agttggtatt cttcgtgaaa
    40021 gacaaaggtg tgttctgcag gttttgtgac cacatctgcc atatcatcgt ggcgagggag
    40081 accggagaga ttatcgacag gagtgtagag ccagctggct tcgctctctg cgatatagac
    40141 aggaggattg ccaaacgtct cgcgaaccaa gtccagactc atgatatggt cataatgggc
    40201 gtgggtcaag agaatagcac agatcggttt gttgatcttc tcgattgtct gacgaatggc
    40261 ttcccaatga ctaccaggat cgacgacgat gaggtgcttt tcgccttcta gataataggt
    40321 attttcatag gcaacaggat tcacggtttt atggattttc atactagctc caatctcaaa
    40381 gaatgtacta atactcttcg aaaatctctt caaactgcgt caactttatc tgcaacctca
    40441 aagcagtgct ttgaacagcc tgcggctagc tttctagttt gctctttgat tttcattgag
    40501 tataaattaa gtatagcaca gttagggaga ataggtaagg atttaaaatg aacttaaaaa
    40561 ccagcatgac tagatgaaga caggctggtt atcaatttat caatattgga aaggtgtcaa
    40621 ttgcccttca taggttgcat aaactccgtc attagcttgt ttgatagacg tgatgtttag
    40681 agtgctaccg tagttggctt ctcgtttgtc gctatattca ctataagtta tcctactggg
    40741 caggttctgg tcgttagcat agtattgaac gactgttttt tatagctttg ctggctgaat
    40801 aggaacaggc agcaaactcc taacattagg agagcaaaga tagaaatagc agtttttttc
    40861 ataggtattc tccttataaa ctaaaggata gaagaaagta tcttgaggat ttttatactc
    40921 ttcgaaaatc tcttcaaacc gcgtcaacgt ctccttgccg tatatatgtg actgactttg
    40981 tcagtcttat ctacaacctc aaagcagtgc tttgagcaac ctgcggctag tttcctagtt
    41041 tgctctttga ttttcattga gtattaattc caaaatccag tcaaggtacc agtgtatgtg
    41101 atacgagttc caccgtttat ctttcgtatc ttcaatggaa ttggggaaat cagaaagtct
    41161 ttgggttaca atatggtttc cgttcttcta tctctccttc tatcacctaa gtttaaaatc
    41221 taacttcgta gtatattatg ggccaataat tcagaattat caagcaattt tgaattattt
    41281 ttttcttatt ctgttccaat ctagttttca tattcttaaa aaagtgataa aatggtagga
    41341 agaattggag agtagagatg ccgaaagaag tgaatttaac aggcgaagaa gttgtcgctt
    41401 taaccaaaga atatttaacg gaagaggatg ttcattttgt ccataaggcc ttggtctatg
    41461 ctgttgaatg ccacagtggt caatatcgca aatcaggcga gccttatatc attcacccta
    41521 tccaagtggc aggtatttta gctaagctaa agctggatgc tgtaacagta gcttgtggat
    41581 tcttgcatga tgtggtggaa gatacagatg cgaccttgga cgatttggaa agagagtttg
    41641 gtcctgatgt gcggatgatt gttgacggag ttaccaagct tggcaaggtc gagtacaaat
    41701 cgatcgagga gcaattagcg gaaaatcatc gcaagatgct catggccatg tctgaggaca
    41761 tccgcgttat tttggtcaaa ctgtctgacc gcttgcacaa tatgcggacc ctgaaacatc
    41821 ttcgaaaaga caagcaggag cgtatttcca aagaaaccat ggaaatctat gccccgcttg
    41881 cccatcgttt ggggatttcc agtgtcaaat gggaattaga agacttgtct ttccgttatc
    41941 tcaatccaac ggagttttac aagattaccc atatgatgaa ggaaaagcgc agggagcgtg
    42001 aggccttggt ggatgaggta gtcacaaaat tagaggagta tacgacagaa cgtcacttga
    42061 aagggaagat ttatggtcgt cccaagcata tttactcaat tttccgcaaa atgcaggaca
    42121 agagaaaacg gtttgaggaa atctatgatc tgattgctat tcgttgtatt ttagataccc
    42181 aaagtgatgt ttatgccatg cttggttacg tgcatgaatt ttggaaaccg atgccaggtc
    42241 gcttcaaaga ctatatcgcc aaccgcaagg ccaatggtta tcagtctatc catacgactg
    42301 tttatggacc aaaagggccg attgaattcc agattcgaac caaggaaatg cacgaggtgg
    42361 ctgagtacgg ggttgcggct cactgggctt ataagaaagg tataaagggg caagttaaca
    42421 gcaaggaatc agctattgga atgaactgga tcaaggagat gatggagctc caagaccagg
    42481 ctgatgatgc taaggaattt gtggactctg ttaaggaaaa ctatttggct gaggagattt
    42541 acgtttttac cccagatgga gctgtccgtt cccttcccaa agattcagaa ccgattgatt
    42601 ttgcctacga aatccatacc aaggtcggtg aaaaagcaac tggtgccaag gtcaatggcc
    42661 gcatggttcc actgacaacc aagttaaaga caggggatca ggttgaaatt atcgccaacc
    42721 cgaactcctt tggacctagc cgtgactggc tcaatatggt caagactagc aaggcgcgca
    42781 ataagattcg ccagttcttt aaaaaccaag ataaggaatt gtctgtcaac aagggtcgtg
    42841 agatgctgat ggctcagttc caagaaaatg gctatgtggc aaataaattt atggacaagc
    42901 gccacatgga tcaagttctg caaaagacca gttacaagac agaagactcc ctctttgcgg
    42961 ccattggttt tggggaaatc ggtgcgatta ccgtctttaa ccgtctgact gaaaaggaac
    43021 gccgtgagga agagcgtgcc aaggccaaag ctgaggcaga ggagcttgtc aaaggtggcg
    43081 aggtcaaggt tgaaaataaa gaaaccctca aggtcaagca tgagggggga gtggttattg
    43141 aaggtgcttc tggtctccta gtgcggattg ctaagtgttg taaccccgtg cctggtgacg
    43201 atattgttgg ctacattacc aagggtcgtg gtgtggctat tcaccgtgtg gactgtatga
    43261 acctgcgtgc ccaagaaaac tacgagcaac gtctccttga tgtggaatgg gaagaccagt
    43321 actctagctc aaataaggag tatatggccc atatcgatat ctacggtctc aaccgtacag
    43381 gactgttgaa cgatgtactg caagttcttt caaatacaac caagaatatt tcaacggtca
    43441 atgcccaacc aaccaaggat atgaagtttg ctaatatcca tgtgtccttc ggtattgcca
    43501 acctctctac actgaccacg gttgtcgata aaattaagag tgtgccagaa gtttactctg
    43561 tcaaacggac caacggctag ttgtcctagc tcttactaga aaggctatta tgaaaatcat
    43621 tatccaacgg gttaaaaaag cccaagtgag tatagaaggc cagattcagg gaaaaatcaa
    43681 tcagggattt ttattgctgg ttggtgttgg accagaggac caagaggaag atttggacta
    43741 tgctgtgaga aaactggtca atatgcggat tttttcagac gcagaaggca agatgaacct
    43801 gtctgtcaaa gatattgaag gagaaatcct ctctatttct cagtttaccc tctttgcgga
    43861 tactaagaaa ggcaatcgtc cagcctttac aggggcagct aaacctgata tggcatcaga
    43921 cttctatgat gctttcaatc aaaaattagc gcaagaagtg cccgttcaga caggcatctt
    43981 tggagcagat atgcaggttg agctggttaa taacggacct gttaccatta tcctagatac
    44041 taaaaagaga tgagaaagac caagcccagt cggcttggtc tttctcatct atcataaaat
    44101 actccaaaaa gaaatcggtt cttgatatgc ttgggggaag tctcttttca ggctttggca
    44161 gatgcgatag gaagggatga gatgtcctag gatgaggaga gttccctgaa ggaaaagtgg
    44221 aatatcactt aaagacacca aggagagaat catcaggcta tcccatagga gaatttgtaa
    44281 agcaaaacgc cagaatctcg gtctaatctg ggaatagagt taactaaagt ggtcacaaag
    44341 ttggtttgaa agataggtca atagcacagg atgaaagaaa atgagccaac cgctataaat
    44401 caaaatccag tcccaagtaa gctccctttt aaatgtcaaa aatgccagca tgattccatc
    44461 aatgacaagg agttgaatgg ttttgatgaa tatgattttt ttcatgctaa aacctccttt
    44521 tccttagaga cactcccata aagagatgtg tttgtcgtaa aagtctggat agttttctcc
    44581 taggtagtca gctgtcatat aataaaaagt agaatggcga gcagtgatga ttggcataag
    44641 agatgaaaaa cgctgagaac taatgaaggc taagagaaca aaaaatagaa aatcaatggt
    44701 gagaatccct aaatagtaga agcgaatctt tttattgatt tgaggataaa tctcagcgaa
    44761 ttgatgtttg agtcggacga ccaagagaaa tagcaggagt ccttgatcaa ggaagaaaat
    44821 taaaccagag agcaagagcc actcaaaaga tgtctcgagt ctagtgataa aaaatgcaaa
    44881 tagtagcaaa tcaataactg caattgctat aaaatggatt ctatagagtt ttttcatgac
    44941 aagaccttcc tcttttatct aacttcattc tactccaaaa gaatgggagt tacaactaaa
    45001 atgataaaaa tagcagaggg gagattctct taagttggct agtattcttt atttgagttt
    45061 ccttctatta tctaacttct tcatcattcc agacaaataa agctccgatt gcattgagga
    45121 tataaaagat gtatttaccg atattggcga agtttccttg aataccagct tttgtcagct
    45181 gaacgaaatt gtaaatcaac caaaagcccc actgagttgt tagtttcaat gcattcaaag
    45241 cattggcaat gagggacagt gcaaaggcaa tagttgttac gtaggcaagg agattcatct
    45301 tgcccccata tccgatatag ttggtcacaa aggcaaagag gaaggcgatg atggaaatga
    45361 tgatgggcgc caattttacc tgtttttggc tcatttggtt gggtctgcct tcttgcgaag
    45421 ctttccattt ctttatagca aaggtataaa tgaggaaggt gacgggatag gtaatgatgg
    45481 ccgccttatt tccaaggata taatcaatag caccggacaa aatggtatta acaataccaa
    45541 agtaatttcc ccatttgctt aatttccccg tgaaacgagt ggacaacatg gaaatcccaa
    45601 cgttagttac ggaaatcaat ccaaagggta caagagctgt ccatagtccc cagtctacaa
    45661 atttatggag gcgtgagttg agataaccag atgcaatcgc aatcccaacg accaaagcaa
    45721 ccccgaagag gtcaaactat ttagatgtag caaaaatttt tagtgatttt ttcataggtt
    45781 aaactacctt tctttttttc aaatattctc ccattttttt caaatattct cacaccaaat
    45841 gaaagtaaaa taaaatgata gaaataaaac cctgaaaata aaactttcag ggttggtagg
    45901 ggacttgaga aattagttga ttttctcgac atagagttgt tttgcaatgt ccatattcac
    45961 ttgtaaatcc tcgtcgttac tgaggatagt gaaggtattg ctgaagccat caaactgctt
    46021 gacttggagc tggtcaccga tgtgaagtga gtgcttgtcc agataatgga gaatgtcaaa
    46081 actatcgtgc acccgagtca ggcggtaggc gccagcttcc ttgatatcag ctagtgggag
    46141 gttattgatt tcaacgagga gttctccctt ggcaggaata gttcctccgt gggggcaggt
    46201 tttagggaaa cctagcagtt tatctagtct ttccacgaac aggtcagaga cagtgtgttc
    46261 caagacctca gcttcctcgt gaatctggtc acttgtatag tctaaatgat gaactagaaa
    46321 aacttcaatc aagcggtgct tacgatagag ctcagagacc agtttgagac cgaggtcagt
    46381 cagtagatag ccacattcct tgtcctttag gatgagattt tcacttttca ttcgtttgat
    46441 catttcagtt acggcagggg gagagacttg catgcgagcc gcaatttcct tgttggtaat
    46501 cttatgcagg tctatgccaa tttcataaat acattttaga tagtcttctt tgtttggggt
    46561 cattcgtttc ctcttgtcta atatctttat ctagtatatc aaaaaaagct agatttctct
    46621 agctgtgact ttttatgtta tacttattgc aagagaaaaa acgaggagat ggatatgacg
    46681 aaaatagctc ttctttcaga tattcatgga aataccaccg ccttggaggc tgttttggca
    46741 gatgctcggc agataggagt ggatgaatac tggcttttgg gagatattct catgccaggg
    46801 acagggcgta gaaggatttt ggacttgttg gatcaactac cgattacggc tagagttttg
    46861 ggaaactggg aagacagtct ttggcatggt gtccgtaagg aattggatag tactcgcccc
    46921 agtcaacgct atctcttgcg ccagtgccag tatgttttag aggaaatttc cctagaagaa
    46981 attgaagtgc tccacaatca acctcttcaa attcatcgtc agtttgggga tttgacggtg
    47041 ggaattagtc atcatctgcc tgataagaac tgggggcgag agttgattca tactggcaaa
    47101 caagaggatt ttgaccgctt ggtgactcat cctccctgtg atattgctgt ttatggacat
    47161 attcaccagc agttgcttcg ttacgggact ggtgggcaat tgattgtcaa tccgggttcg
    47221 attggccaac ctttcttttt ggacgctcag ctacggaagg acttgcgggc ccagtatatg
    47281 attttggagt ttgatgacaa gggcctggta gatatggact tccgacgggt agactacgat
    47341 gtggcagctg aattgcagct ggctaaagac ctgagacttc cctattttga ggtttactat
    47401 gaaagtctgg tcaatgggat ccaccatact catcatcagg aatttttgag agaattggct
    47461 cagaaagagg gctgcgaccg ggagttagac gactggttga aaagtggtaa cgattgacat
    47521 tacaactaaa aagggtataa taatagaaaa agaagagtag aggcagggta gcctcgtaaa
    47581 aaggagaaga ggatgcaaat tccaagtaga tttaccattg cgactcatat gctgataatc
    47641 attgccctcg aggggaagga aagcaaggtg accagtgatt ttctggctgc tagtgtcggg
    47701 gtcaatcctg tcattatcag aaagatcttg tcccagttga agaaggcaga gctgatttca
    47761 gtagcgcgtg gaacgggcgg aacagagatt gtcaaggacc ttaaggatat tagtctttta
    47821 gatgtttatc aggcggtcga atgtcttggt aagacaggtc aactcttcag tttccatgac
    47881 aatccgaatc caaattgccc tgtaggagct catattcatg atgttttgga tcaaaaattg
    47941 gagagaattc agttgactat ggaggcagaa cttggtcaaa ccagtctaga aaaagtcgtg
    48001 gccgatgcag agagtcagat gaaggattaa gagggataaa tgccctcttt tttctttgga
    48061 taattatgat aaaatgtagc tattaaagga gtaagaaatg tatctcgtta taggaattgt
    48121 attagccttt atagtgtcat tttggaagga taatagaagt ttgtggaatc cagtattatt
    48181 tttattatcc ctcatttcaa gttattttta tctatcctac cttttttata aaaatggata
    48241 cgagaatgtt cagttagctt tttatgtatt tgcctttgtc ttacttcctt ttttgctttt
    48301 tctaagtggc atctttttaa tctataatgg ggtcattttg ttgaagcgag agggacgttc
    48361 caagccccat tatctctcaa tgctctttga tttttattga ctattagatt ctatttaaaa
    48421 agacttagaa tgcacatgaa agtatgtatt ctaggtcttt tgttttgtat acatttaatt
    48481 ttcaagagta ttatctattt ttccatgcct ggtaacgagt atcaatcaat aactgggtaa
    48541 ggcgacccaa ggtttctctt tcttctggag tgagggattg agcttggaca aagagatgat
    48601 gaatgtattc aagcgccttt aaggaagcca agtcattgat agagctaata ccagcctcaa
    48661 gaatagtgcc aaagaagagg tcgaagtaga gctgaagttc ttcgtcaggg actgtggcca
    48721 cccattcttt aaaggttgtg tctacttgct ggctatcact gttggtctta tccagttgga
    48781 cgaagtgctt gtcctcaatc tgccaactaa aggtatcgtg ctgggcgatg ccacccaggg
    48841 cagtactctg aacgatgatt tggtgagcag gaatttccag catcataccg ataatggaac
    48901 cttgtggaat gaatatcttg cttctatcca ttatcctttg ataacccgca gtctgtgtca
    48961 attcttgatg gagaccaggt gcatcaaatg tataaactgc tgtgatctga ttttgcaaac
    49021 tttgctcaat ttggctagca gcatagatag cgagatttcc tcccttggaa tgcccagcta
    49081 gaataacctt ttgcttagga tgatgggcaa aaaagttctt taaatagcga agggcgtgct
    49141 tttgagcagg aatttccttc atataggtca ggtggaaatc ttccttccag ccaatgatac
    49201 tgtcatctgt cccacgaaag acaatcagat aggtatcgag gctgacacga taagtcatag
    49261 ccgcaaattg cttttgcagt tcagggtcga tgtcgttgat aaaatgggag agtttgcaat
    49321 ttttgaagcg cttgtgttga gccaattcat ctaataattg aaggcgattt ttgctagtaa
    49381 gcatggtggg atctcttgga acctgaggtg ctagatctaa aagacgttga ggaagtgtgg
    49441 agaccagatt atcaaaggag aggtaggtga tttctattaa ggttagaatg tctaactcat
    49501 tcaagggaag gtcgtaataa gaatcatatg cgacatcttt cagatagtca aaaatattgg
    49561 ccataagagc tcctttcttt ttatttatct tagcaaattt ccctcaaatt agctagtagc
    49621 attgcctgtt tgtactggct aaaaacaggc tatttcaaat tcagtttcag accatctggc
    49681 atggaaaaat ctgttataat aatggaaaag gagaagcgca tgcacaagat tttattagtg
    49741 gaagatgatc aggtcattcg tcaacaggtc gggaaaatgc tctctgaatg gggatttgaa
    49801 gtggtcctgg tagaagactt tatggaagtt ttgagtctat ttgttcagtc ggaacctcat
    49861 ctggtcctca tggatattgg tttgcccttg tttaatggtt atcactggtg tcaggaaatc
    49921 cgcaagattt ccaaggtacc tatcatgttt ctttcttcga gagaccaggc tatggatatt
    49981 gtcatggcaa tcaatatggg ggcggatgac tttgtgacca agccttttga ccagcaggtt
    50041 cttttagcta aggttcaggg cttgttgcgt cgttcctatg agtttgggcg tgatgagagt
    50101 ttgctggaat atgctggtgt tatcctcaat accaaatcca tggatttaca ttatcaaggg
    50161 caagtcttga atttgaccaa gaatgaattc cagattttac gcgtgttatt tgagcatgca
    50221 ggcaacatcg tagcacgtga cgacctgatg cgggaacttt ggaacagtga ctttttcatt
    50281 gatgataata ccctctctgt caatgtggct cgtttgcgta aaaagttgga ggagcaggga
    50341 ttggtaggat ttatcgagac caagaaagga atagggtacg gattgaagca tgcttgattg
    50401 gaaacaattt tttctagcct atctgcgctc ccgtagtcgt ctttttatct atctgctttc
    50461 tttggcattt ctggtcttac tctttcagtt tttatttgcc agtctaggaa tttacttcct
    50521 ctactttttc ttcttgtgtt gctttgtaac catcttattt ttcacttggg atatattggt
    50581 ggaaacgcag gtctatcgcc aggaacttct ctatggagag agggaagcca agtctccttt
    50641 ggaaatagct ttagcagaaa aattagaagc gcgtgagatg gaactctatc agcagaggtc
    50701 aaaagcagaa agaaaactga cggatttgct ggattactat accttgtggg tccatcagat
    50761 aaagaccccc attgcagcca gtcaactctt agttgcagaa gtggtcgacc gccaactgaa
    50821 gcagcaacta gaacaggaaa ttttcaaaat cgactcctat accaacctag ttttacagta
    50881 cctgcgttta gaaagtttcc atgatgattt ggtcttaaag caggttcaaa ttgaggactt
    50941 ggtcaaggaa ataattcgta aatatgctct tgtctttatt caaaaaggct taaatgtcaa
    51001 tctacatgac cttgataaag aaatcgtgac ggataaaaag tggctgctag tggttattga
    51061 gcaaatcatc tcaaacagtc tcaagtacac caaggaaggt ggtctggaga tttatatgga
    51121 tgaccaagag ctttgtatca aagatacggg aatcgggata aaaaacagtg atgtcctccg
    51181 agtatttgaa cgtggctttt caggatacaa tggccgtttg acccagcagt cctctggact
    51241 tggcctttat ctatctaaga aaatttctga agaactgggg caccagattc gtatcgagtc
    51301 tgaggtcgga aaaggaacga cagtgcggat tcagtttgct caagtgaact tagtccttga
    51361 gtaaaaatag atgagaaaaa gcctccagat tggaggcttt tatgctagac tcttatttct
    51421 caacgcgtga tttgttggcg atatcagcta ggatagcttg aacaaaatta tcaactgaga
    51481 cagtttgtgt ttctttttgg ccgtagcgac gaacgttgac tgtttcgtct tccatttctt
    51541 tgtctccaac aattaattgg taaggaatct tgctggtttg tgaagcacga atcttgaact
    51601 gcattttttc attgcgctca tctacgtctg cacggacacc gcggtcacgg agtttcttgg
    51661 ccacttccca agcgtagtcc acgtgttttt cgttagatac tgggatgagg gttacttggt
    51721 gtggtgccag ccatgttggg aaggccccct tgtagttctc aatcaagata gctgtgaagc
    51781 gttccatagt tgagataacc ccacggtgga tcatgactgg acggtgatct tcgccatcag
    51841 ctccgatgta tttgaggtcg aagcgttctg gcaacaagaa atcaagttgg atagtagaaa
    51901 gggtttcttc ttttccaagg gcagttttaa tctggatatc caattttggt ccgtagaagg
    51961 ctgcttcacc ttcggcttca aagtagttca cgcccatttc atcaagagct gcacgaagca
    52021 tggtttgggc attttcccac atctcatcgt tatcaaagta cttatgagta tcttgagggt
    52081 cacgaagaga gaggcggaag cggtagtcag tcaagttgaa gtcttcataa acatcgataa
    52141 tcaactgaag ggcacgttgg aattcttctt ggatttgttc tggagtaacg aataggtgac
    52201 cgtcgttgag tgacatttca cgtacacgtt gaaggccagt gagggcacca gatttttcgt
    52261 aacggtgcat cataccgatt tcagcgatac ggattggcaa ttcacggtaa gagtgaacat
    52321 ggtgtttgaa aacttggatg tggtgcggac agttcattgg acgaaggaca aattcttccc
    52381 cgtcacccat gtccatggtt gggaacatgt cttcttggta atgatcccag tgaccagaag
    52441 tcttgtaaag ctcaacagaa gcaagtggtg gagtgtagac gtgttggtag ccagaagcca
    52501 actctttgtt tacgatgtag cgttccaatt cacgacggat agtcgcacca tttggcaacc
    52561 agaatggcaa accttgtccc acttcttgtg aaattataaa gaggtcaagc tctttaccaa
    52621 gtttacggtg gtcacgttcc ttagcttctt cacgcatttg aaggtagttt ttcaagtctt
    52681 tcttgtcaaa ccaagctgta ccgtagatac gttgcatcat agcgttgtcg ctgtttccac
    52741 gccagtacgc accagctaca tggagaaggt ggaagatttg gatacgacct gttgatggaa
    52801 cgtgaggtcc acggcagagg tctacatatt caccctgacg atagatagtc aaaccgcctt
    52861 cgtcttctga gtgttcttca atcaattcca acttgtaagg gtcatttttg aagatttcac
    52921 gtgcctcgtc tttagtcact tcttcacgaa tagatgggaa gttttctttg acgatttttt
    52981 gcatttcttc ttcgatacga ggaaggtctt cgttagagat ttgaccagct gtgttgtcag
    53041 tatcgtagta gaaaccatct tcgatggctg gaccaactcc caagtgaatg tctgggaaaa
    53101 gacgacgagc tgcttgggcg aacaagtgag ctgctgagtg acgcaagatt ggaagggcat
    53161 cttcgtgatc aggtgtcaca atttcgatgc ttccatcttc agtgatagcg cgagtagtgt
    53221 cgatgagttt gccgttgaat ttaccagcca aggctttttt agctagggaa ttgctgatag
    53281 attgggcaat ttcaaaagtt gttacgccag attcgaattc acgaacagcg ccatctggga
    53341 aagtaatgtt aatcatgatg ttctcctttt ttattatttc atagtttcta agcattgatt
    53401 ttttatcagc agactacttc caagtcctaa cgttcaattg cttttcttta tcagagagga
    53461 agttttccat ttccgtcaga atgtctatat ccaaacgttg agaaagttct aatagccacc
    53521 agatattttc tgaaagtttt tgttccagtg tgtagggtgt ttcatcatag tagcgtcctt
    53581 gctttgtcat caccagtcgt tggaaatttc caatatcatt agataaagcc aagaggtctt
    53641 cttctaccgt ccacttggaa tcatgatgct taacttccag ttcgtgataa gcttgtcgga
    53701 ttgcccaact gcgctccact aattcttgca actccataat tagtatccta ataaaaaaat
    53761 gcgacatcct cgaaaggacg tcgcaacgtg gttccacctt catttatgta cctcaaaaga
    53821 gagggacacc tctgattggc tctaacgtgg ccaccgtttt atgttttcat aaaaaactca
    53881 agagtagtat cagtttagac ttcctatgcg tttccagcaa ccacgcactc tctagtagaa
    53941 agggactaag tgacttgtct ctatggatta ttatagcatg attgtgagat ttttcaagga
    54001 ttttgtgaaa gttttttgtt tttcatattt tgtagaatat gcttgatgct aataccagaa
    54061 tccatgccca ccagagcaac tgtttcatag attagcaagt aaattagtat aaactcacca
    54121 aaggttatga tagtaaagta aaagagcagt ccgttaccaa ctaaccatca aagtgagaaa
    54181 cggaaacggt agctatagag taacgataca atcaagatta ccagaggtgt aaagaagaga
    54241 agattgttta tatagtgtaa gggggtcaga aacaactagc aagaacaact cataaagtgg
    54301 ccaataaaag aataatatga ccagatagta ggggagatgg gaatagaatc tacgcatgat
    54361 aatcacctcg ttttaaaaaa acagacaact tagatctctt gctatgatta ttatagcatg
    54421 tttaaaacaa gaaagtaaat ttgttgacaa agaagatttt tcttttcact agaatcatgg
    54481 ttagttttct tggtagaaat attttgataa taattaagca agactattga cattgattat
    54541 taagagtgtc acaattgttg taactaaaac aattacaaca agagaggtat aaaaaatgaa
    54601 actagcagtt attgcagcaa atggacaagc ggggaaggca attgttgaag aagcagtcaa
    54661 acgaggacat gaagtaacgg ctattgttcg ttctgaaaac aaaagtcaag ctgagtctat
    54721 tattaaaaaa gatttatttg agttgacaaa agatgatctt actggatttg atgctgttat
    54781 ttcagcgttt ggtgcttata caccagatac gctaccgctc cacagcaaat caatcgaact
    54841 atttaatcag cttcttgctg gaacacagac acgttttcta gttgtagggg gatcaggaag
    54901 cttttatata gatgaaacaa aaacgacacg acttttagat acgtctgatt ttcctgaaga
    54961 atttaagcca ctagcaaaag ctcaagcgga tgaattggat cttcttcgta caaaaaataa
    55021 tctcaactgg acttttgtca gtcctgctgt agattttatt cccgatggtg aaaaaacagg
    55081 aaactacatt ctagcaggag aaatttttac tactaatgaa aaaggaataa gccagattag
    55141 ttatgcagat tatgctattg gattggtaga tgaacttgaa aaaggtcatc atataaaaga
    55201 acgtatctct ttacttgaaa aataataact atgagagtat taatgtttga cagaaaattt
    55261 aaatcttggt aaaataggga ttgtcgtaaa gacaaataac ttcttcttgg ttacaggcat
    55321 gccaacctgt cactcggatg aagccaaata aaaaggagaa acatcatggc aatctcaaaa
    55381 gagaaaaaaa atgaaatcat cgcacaatat gcacgtcacg aaggtgatac aggttcagta
    55441 gaggttcaag ttgctgtcct tacttgggaa atcaaccacc ttaatgaaca catcaaacaa
    55501 cacaaaaaag accacgctac ttaccgtgga ttgatgaaaa aaatcggtcg ccgtcgtaac
    55561 ttgcttgcat acttgcgtaa aaacgacgtt aaccgttacc gtgagttgat caactctcta
    55621 ggacttcgtc gctaattcaa gatacaaagg ctgtcaaaag cacaaagcaa aaataggaaa
    55681 attgacgaag aaacttcagt ttctaggaga ttttatcttt tttgccaagt gcttaggccg
    55741 tgttcaattg agcatatctt gataatgaag ctactctaaa ttgggtagct tttttgcgtt
    55801 gtcaccttac ctcgatatac tcaagtataa tcttcggtta cggttcctag cactgtaagg
    55861 taaaataaac cagcttttct cccttcgggg agattttttt ttgtttcact gaaagtttcg
    55921 tacgatcttc gcctcgtcgc ctagtctata aacgatttat ccagcaagaa tcatgatgct
    55981 aagggcgtca aaaatccgta tgaaaatagg gaaatggcac agtgttcgat gaacgcaagg
    56041 agtttcatct ttttcactag gattttagtc cgggctcaaa tcagctctct gacttcagag
    56101 ggctttttta ttgaggtttt atcggtaaca attttggaga ctacaaaaac ctcaaatggt
    56161 atcagctaat tacaccataa aggtgcgcag ttactcggct tttcaagccg agtagctgta
    56221 tgcaagcccc ctagaagagc ccactcttta caaagtaaag tatagtatgt tatactttac
    56281 atggaagtag tcactgaatt ccagttagaa attactttgt aactacgttt tgaggaggag
    56341 taaaatgctt tcctacgttc gacattaccc actagcgata gctaaattaa tgtgtctgtg
    56401 ctctcctaaa atctgctgat ttattactga ctaatacagg aggttttttt atgggacaga
    56461 caatcatatc tgctattggt gtttatattt ccaccagtat cgattattta attattttaa
    56521 ttattttatt tgcacaacta tcacagaata aacagaaatg gcatatttat gcggggcaat
    56581 atctaggcac aggcttactt gtaggggcga gtttagttgc tgcttatgtc gttaatttcg
    56641 tgcctgaaga atggatggtt ggattgcttg gtttaatccc tatctattta gggattcgct
    56701 ttgcaattct tggagaagat gcggaagaag aagaggaaga aattattgaa agattggaac
    56761 aaagcaaggc aaatcaactg ttttggacag ttacattgct gacaattgcg tctggcggag
    56821 ataatttagg tatctatata ccttattttg cttcgttaga ttggtcacag accctcgtgg
    56881 ccttgcttgt gtttgtaatc ggcataatta tcttttgcga gattagtcgg gtgttatcct
    56941 ctattccgtt aatattcgag acaattgaaa aatacgagcg aatcattgtg cccttagtat
    57001 tcattctact tggactatac atcatgtatg aaaatggcac gatagagact tttctgatcg
    57061 tgtagatttt tttgtttcac taggatttta gcccgagctc aaatcagctc tctgattttc
    57121 agagggcttt ttcattgagt ataaatggac aatcttaaag ttactctatt gtagagtggc
    57181 ttttgatttg attaggagat tcttataaat atagtaaaat gaaacaaaaa caggacaaat
    57241 cgatcgtgac agtcaaatcg atttctaaaa atgttttaag aagtagaggt gtactattct
    57301 agtttcaatt tgatatataa atgaaaacct tagctgtttg gccaaggttc atttcttcta
    57361 tgcaagttct tctcttttct tatctgggtt ccagatgaag cttgcgataa agctaaagat
    57421 gatggttagg atagcgagga taatagcaag gatgagggca gggatgcgga taaaccacca
    57481 gagtggattt ggttttttat cattgtgcca ttgtttcgtt tcttcgtcca gacgttggaa
    57541 ttctgtttga atacgattgg cgactgtttc aatgccttca tcattcattt tcttgatatc
    57601 tgagatatcg attggatttc caaagttcat atcgacacgt tcacggctaa tcaagccctt
    57661 caaagtcatg ggaccggtgt aggtaaccgg catgatacgg accttggcca ttttggcaat
    57721 cagtgctgcg ccccccttga catcgtttga gtggcggcta ccacttggaa acatgatgag
    57781 agagcggtca ctttttttga gaacgttgat aggatatttg atggctgagg cgctgggatt
    57841 ttcacggtcg atgggaaagg cgccacacat acgaatccac caaccaaaga tacggttggt
    57901 aaagagttct ttttttgcca taaagatgaa ctgttttggc ttggtcgcaa aggccatata
    57961 aacaggatcc caccaggtac ggtgaggcgc aactaaaata taattttcat cttgattagg
    58021 aattttatca gtattatgat agtgagcatt gccattgatg gaccataaga gcaatacaac
    58081 taatccacgc aaataagtat aaaacatgcg atctccttcg attgttttct tgttattatt
    58141 ataccttatc aaaggagggc tggcaaactt ttcccttgac tagatgcata tttgggatga
    58201 aattagaatt ctgttaaaaa aaatgatata atagaattta tggataaaaa taagattatg
    58261 ggattaaccc aaagagaagt caaggaaaga caggctgagg gtttggtcaa tgactttacc
    58321 gcatcagcca gtaccagcac ttggcaaatc gttaaacgaa atgtctttac cctttttaac
    58381 gctttgaact ttgccattgc tttggccctt gcctttgtgc aggcttggag caatctggtc
    58441 ttctttgctg ttatctgctt taacgctttt tctgggattg tgaccgagct acgagccaaa
    58501 cacatggtgg acaagctcaa tctcatgacc aaggaaaagg tcaaaaccat ccgtgatggt
    58561 caggaagttg ctcttaatcc tgaagaatta gtgctaggag atgtcattcg tttgtctgca
    58621 ggagagcaga ttcctagtga tgccttggtt ttggaaggct ttgcggaagt caatgaagcc
    58681 atgttaacgg gagaaagtga tttggtgcaa aaggaagttg acggcttact tttgtcagga
    58741 agtttcctag ccagtgggtc agttttatct caagttcacc atgtcggtgc agacaactat
    58801 gctgccaaac tcatgcttga ggctaagacc gttaaaccca tcaactcccg tatcatgaaa
    58861 tcgctggaca agttggctgg ttttactggg aagattatca ttccctttgg tctggctctc
    58921 ttgctggaag ccttgctttt aaaaggcctg cctctcaagt catccgttgt aaactcgtcg
    58981 acagctcttt tgggaatgtt gcctaaggga attgcccttt tgaccattac ttcgctcttg
    59041 actgcagtga ttaagttggg cttgaaaaag gtcttggtgc aggagatgta ctctgttgag
    59101 accttggcgc gcgtggatat gctctgtctg gacaagacgg gcaccatcac ccaaggaaag
    59161 atgcaggtgg aggctgttct tccactgacg gaaacttacg gtgaagaggc tattgccagc
    59221 atcttgacta gctacatggc ccatagtgag gataagaatc caactgccca agccattcgc
    59281 cagcgttttg tgggagatgt tgcttatcct atgatttcca atcttccctt ctcgagcgac
    59341 cgcaagtggg gggctatgga gttagaaggc ttggggacag ttttcttagg ggcacctgag
    59401 atgttgctgg attctgaagt cccagaagcc agggaggcct tggagagagg atcacgtgtc
    59461 ttggtcttag ctctcagtca ggagaaatta gaccatcaca aaccacagaa accatctgat
    59521 attcaggctc tagccttgct ggaaatcttg gatcctattc gagagggagc ggcagagacg
    59581 ctgaactatc tccgttctca ggaagtgggg ctcaagatta tctctggtga caatccagtt
    59641 acggtatcca gcattgccca gaaggctggt tttgcggact atcacagcta tgtcgattgt
    59701 tcaaaaatca cggatgagga attgattgct ctggcggagg agacagcgat tttcggacgt
    59761 gtttcccctc atcaaaagaa actcattatc caaacgctga aaaaagcggg tcatacaaca
    59821 gctatgactg gggatggagt taatgatatc ctggctcttc gtgaggcgga ttgttctatc
    59881 gtaatggcgg agggagaccc ggcaacccgt cagattgcca acctggttct cttgaactca
    59941 gactttaatg atgttcctga gattcttttt gaaggtcgtc gtgtggtcaa taacattgcc
    60001 cacatcgctc cgattttctt gataaagacc atctattcct tcctgttagc agtcatctgt
    60061 attgccagtg ctttactagg tcggtcagag tggattttga ttttcccctt cattccgatc
    60121 cagattacca tgattgacca gtttgtggaa ggtttcccac catttgttct gacttttgag
    60181 cgaaatatca aacctgttga gccaaatttc ctcagaaaat ccatgcttcg tgccctacca
    60241 agtgccctca tggtcgtgtt tagcgttctt tttgtgaaaa tctttggaac gagtcaaggt
    60301 tggtctgagt tagaaatctc aactctcctc tattatctct tggggtcaat tggtttctta
    60361 tccgtattta gagcctgcat gccattcact ctatggcgag tcctcttgat tgtctggtca
    60421 gtaggaggct tcctagccac agctctcttc ccaagaatcc aaaaactgct tgaaatttca
    60481 accttgacag aacaaacgtt gcctgtttat ggtgtcatga tgttggtctt tacagtgatt
    60541 ttcatcctga ctagtcgcta tcaagctaga aaataaagaa agactgcaat ctgtggattg
    60601 cagtttttta tacgatggat ctatcgtaga tctgatgtgc aaggcctacg tgtctattat
    60661 ctatcggtga acccaagagt gattctcaag cctgcttgga ttgaggtaat agattcaaat
    60721 atctgtagtt agactatttg aagtttgatg taagaaagag aaagcgacag attgaagtaa
    60781 ttttaactct cttctattgc tagaacaaat ggtcggatag gttggtagtt tgaaaatgaa
    60841 gatgcaatct attgttaaat ggaacatagt gttatttatt agaaaatcgt ttggtttatt
    60901 tcttatcaaa tacgaaaagc aacttaaata tttcaactaa aatagatgtt atgaagaaaa
    60961 ggtaaaatga ttttggtata gtgaggttct gttctatttg atatcatatt tttgataaaa
    61021 acaaaaatgt ccattgcaaa ggacaaaatg cgaagtatat tattttttga aagcgatata
    61081 atggaatcat aaaggaggtg tatcgtgtct agaaaacaag aacaaatgga aacgttgttg
    61141 ctccttttgc gagatagtaa ggattatata tctgctaaag tattgggaga aaaattaaat
    61201 tgctctgata aaacggttta tcgccttgtc aaggtaatca acaaagattg tccggtagaa
    61261 gcattcattt tatctgaaaa aggcagaggt ttcaaattaa atccaagaag ttccctcgtg
    61321 gacgttgatg ggaattttac agaggctttt gatcctgaag taaggcgtga aaaattacta
    61381 gaacgtctct tgttgactgc tcctaagcca cattctattt atgatttagg agaggaattc
    61441 tacgtaagcg agtcagtagt actaaaagat cgtcagatat tacaagagag tctagcaatt
    61501 tatgggttag atttaaaaat gagacaacga aagcttttta ttgatgggga tgaggctcaa
    61561 attcgttcag ccattctaaa tctactgcca atgtttaatc agttggattt agagcaaatt
    61621 acacagaata aggttcagcc tcttgacgga gaacttgctc acttttgttt gggattactg
    61681 attacacttg agagagaatt gggggtaaac attccctatc catataatat aaatattttc
    61741 tctcacctgt atatttttat cagtaggaat cgtcgtagta ctagtattca tgttgtagca
    61801 ccttcaaaac ctactattgt tgatgagaaa atttacagtg tctgtcaaaa aattattcaa
    61861 gaaattgaac aatattttaa gatgaaggtt gatgcagttg agattgacta tctttatcaa
    61921 tacgttgtat cttcgagatt gcaaaaacca ttttcttccg ggaagcttcc tttttctcag
    61981 cgagttttag atgtcactca ttactatttt agccgtatgt gtatggacaa tagagagatt
    62041 gaaacgacag atcctgactt tgttgacttg gcgagtcata tcagtccctt actgaggaga
    62101 ttagataata gagtacagat taagaatagt cttttatcac aaattctttt aacctatcct
    62161 aatctagtta aagagttaac aactatttct aaagaagtga gtctagtatt tggttttgcg
    62221 tccttgagtc tggacgagat tggttttcta gtcttatatt ttgcacggtt tcaagaaaag
    62281 cgagcacgtc ctctaaaaac agtagtgatg tgtacatcag gtgtcggaac ttcagagctt
    62341 ttacgagcac gattagaaaa gcaatttact gaattggata ttattgatgt agttgcttat
    62401 catcaattag atgagctgat aaatctatat ccagatttag atttcattgt gacgacggta
    62461 gctttgcagg aaccagcaag tgtcccgttt gtcctagtta gtgtttttct aaccgagggt
    62521 gataaacaac gtcttcaagc aaaaattcag gagataaact atgaataatc tttcgcttgt
    62581 ccttatggat atatctgttc aaaatcgtca agaagcctac aaagaattag caaatcaaat
    62641 cagccttctt gtttctgaag atacagaaaa aatagaagag cttctatatt accgtgagag
    62701 acagggaagt atagaggttg ctaaaggtgt tcttctacca cattgtgaag gaaactttca
    62761 acatcatgtc ttagtgatta ctagattaaa atcacctatc agagaatggt cgaaggatat
    62821 ccagtgtgtt gaccttatta tcggtttggc cattgcagta tcacaggaca agtcatgtat
    62881 taaaacattg atgagaagac tagcagatga atcattcata aatcaattaa aacagttaac
    62941 aaaagaagaa ttacgggaga taatatatgg aaatcaaaga tattcttaat gtgagtctga
    63001 tccagacgga tttacagatg cagagcaaag aagaggtttt tgaggcatta gctcaactat
    63061 tggttgagac gggttatgtg tctgatagag accaatttat cgaaggtctg tatcagagag
    63121 aggcagaagg acagaccggt attgggaatt atattgctat tccccatagc aagagttctg
    63181 ctgtggagaa ggcgggggta gtcatagcta taaatcacaa tgagattcct tgggagacca
    63241 ttgatgggaa aggggtcaaa gtaattgtac tctttgcagt tggtgatgat acagaagctg
    63301 ctagggagca tttgaagacc ttatcactct ttgctcgaaa acttggtaat gacgaagttg
    63361 ttgccaaatt agttcgggct cagacatctg atgatgtgat tgcagctttt tgttaataag
    63421 aaaaaatttt ggagggtatc cgtatgaaaa ttgttggtgt tgcagcttgt actgtgggaa
    63481 ttgcccacac ttatattgca caggaaaaat tagagaatgc cgcaaaggta gctggacatg
    63541 tgattcatgt tgagactcag gggacaatag gggtagaaaa tgaattgagt caagagcaga
    63601 ttgatgcagc ggatgtagtt attttagcag ttgatgttaa gatttctggt atggaacgct
    63661 ttgagggtaa aaagattatc aaggttccaa cagaagtggc agtcaaatct cccaataaac
    63721 tgattgctaa agctgttgag attgttacga aataactgaa aatatttaag gagaaaatat
    63781 atgttgaaac acttaaactt aaaaggtcac ttattgacag ccatttccta tatgattcca
    63841 attgtttgtg gtgcaggatt cttagttgcc attggtttag caatgggggg tggtgttcct
    63901 gacgctcttg tagcaggaaa attcactatc tgggatgctt tagcaactat gggtggtaaa
    63961 gcccttggtc tcttgccagt tgttattgct acaggtttgt cttactcgat tgctggtaag
    64021 ccagggattg caccaggttt tgttgttggt ctaattgcca attctgttgg ttcagggttt
    64081 atcggtggta tcttgggagg ttatatagct ggtttcttgg ttcaagcgat tattaaaaag
    64141 gtcaaagtac caaactggat taaaggttta atgccaacct tgattattcc ttttgtagcc
    64201 tctttggtaa gtagtttgat tatgatttat attattggag cgcctatcgc agcctttacc
    64261 aactggttga cgagcttatt acaaagcttg ggaagtgctt caaatggttt gatgggggca
    64321 gttattggag ttctcagtgc tgttgacttt ggtggcccac ttaataaaac agtctatgcg
    64381 tttgtgttga ctttacaggc tgaaggtgtg aaagaaccat tgactgcttt gcaattggtg
    64441 aatactgcta caccagttgg atttggattg gcctatttta tcgcgaaatt actcaaaaaa
    64501 aatatctata ctcaagagga aatcgaaaca ttgaaatcgg ctgttcctat ggggattgtc
    64561 aatattgttg aaggtgtaat tccgattgtt atgaataact tggttccagg tctcattgca
    64621 acaggtatcg gtggtgctgt tggtggtgct gtttctttga caatgggtgc tgattctgcc
    64681 gtgccatttg gtggagtgct tatgttacca accatgactc gtccagtagc tggtatttgt
    64741 gctttgttag ccaacattgt agtcacagga cttgtctacg cgattttgaa aaaaccaata
    64801 aaacatacag aaccagttat gactgttgaa gaagagattg atttgtcaga tattgaaatt
    64861 ttgtaagagg gtaacgatgt caagaattga attttcacca tctttgatga ccatggattt
    64921 ggacaaattc aaagagcaga ttactttttt gaatgataaa gtagcatctt atcatatcga
    64981 tattatggat ggccattttg ttcccaatat taccttgtct ccttggttca ttcaagaagt
    65041 tcaaaaaatt agtgacacac ctttatcagt tcatctgatg gtcacagacc caaccttttg
    65101 ggtagatcaa gttctcgatt tacaatgtga gtatatttgt attcatgctg aagttctgaa
    65161 tggtcttgct tttcgtttga ttgataaaat tcatgatgca ggtctaaagg ctggtgttgt
    65221 ccttaatcct gaaacacctg tttctacaat ctttccctac attgatttac ttgacaaagt
    65281 aactattatg actgtagatc caggttttgc aggacaacgt tttttgaagt ctaccttgta
    65341 taaaatccaa gaactccgtc agcttagagt tcagaatggt tatcactaca tcattgagat
    65401 ggatggttct tcgagtcgta agactttcaa acaaattgat gtggcaggac cagatattta
    65461 tgttataggt cgcagtggat tatttggttt ggatgacgat attgccaaag cctgggatat
    65521 ctgttctaga gattacgaag aaatgaccgg aaaaacaatg ccaatcaaat aatggtttga
    65581 gaagaaattt attagttagg aggaatatat gtcactacaa tcagttaacg ccattcgttt
    65641 tcttggcgta gatgctatta acaaatctaa ttctggtcac ccgggaatcg tcatgggtgc
    65701 tgcgccaatg gcttatagct tatttacaaa acaccttaga attacacctg agcagccaaa
    65761 ctggattaac cgagatcgct ttatcttgtc tgcgggtcat ggatcaatgc tactgtatgc
    65821 tctcttgcat ttaacagggt ataaggatgt atccatggac gagattaaaa atttccggca
    65881 atggggatct aagacacctg gtcatcctga agtgacgcat acgtctggtg tggatgcgac
    65941 atctggtccg cttggtcagg ggatttctac tgccgttggt ttcgcccaag cagagcgttt
    66001 tttagctgct aagtacaaca aagatggttt tcctattttt gaccattata cttatgttat
    66061 cgctggagac ggtgacttca tggaaggagt gtctgcggag gcggcttctt atgcaggtca
    66121 tcaagcttta gataagctta tcgtcctcta cgactccaac gatatctgct tggatggtga
    66181 gaccaaagat actttctctg aaaatgttcg cgcccgttac gatgcttatg gttggcatac
    66241 agttctggta gaagatggaa cagatttagc agcaatttct acagcaattg agacggccaa
    66301 gttttctggt aagccgagtt tgattgaagt gaaaacggta attggttacg gctcacccaa
    66361 taaaagtggt acaaatgctg ttcatggtgc accactagga gcagaagaaa caggagcaac
    66421 tcgtaagttt ttgggatggg attacgatcc atttgaagta ccagaggaag tatattctga
    66481 tttcaagaca aatgtagcgg atcgtggtca ggaggcatac gatgcttggg ctagtttggt
    66541 gtctgattac aaggttgctt atcccgaagt tgctagtgag attgacgcta ttgtagctgg
    66601 aaaatcccct gtaaccatta ctgaaaaaga cttccctgtc tatgagaatg gcttctctca
    66661 agcaactcgt aattcgtccc aagatgctat taatacagca gcagcagttt taccaacctt
    66721 cttaggtgga tcggcagact tagctcactc caacatgacc tacatcaagg cagatggctt
    66781 acaagataaa tataatccat taaaccgcaa tattcagttt ggggtacgtg aatttgccat
    66841 gggaacaatc ctcaatggaa tggctcttca tggtggttta cgagtttatg gcggaacctt
    66901 ctttgttttc tctgactacg tcaaagctgc tattcggcta tcagccattc aggagttgcc
    66961 tgtaacttat gtctttaccc atgattcaat tgccgttggt gaagatggtc caactcatga
    67021 accagttgaa catttggcag gtttacgctc aatgccaaac ttgactgtta tccgtccagc
    67081 ggatgcccgt gaaactcaag cggcttggca tcatgccttg accagtacca ccactccaac
    67141 tgtcattgtc ttaacccgtc aaaacttggt agttgaagaa gggacagact ttggtaaggt
    67201 cgctaaagga gcctacgtcg tgtatgatac cccgggattt gatactatta tcattgctac
    67261 aggatctgag gtcaatctag ctatcaaagc tgctaaggaa ttggttttac aaggtggtaa
    67321 agtacgtgtg gtatctatgc cctcaaccga actatttgat gctcaagatg ctacctacaa
    67381 ggaagacatt ttaccatcta agactcgtcg tcgtgtggcc attgaaatgg cagcgaccca
    67441 aagttggtac aagtatgttg gtttggatgg cgcggtcatc ggtattgaca tcttcggtgc
    67501 gtctgcccca gctcagactg tgattgataa ttatggattt acggtagaga atatcgttgc
    67561 tcaagttaag tccctataga aaccaattac aatgaagata cagctgttgt cagactagca
    67621 gatgtagtga tagacactaa tcagatgatt ggttatttaa aaactataat gagaatgtaa
    67681 taatttatct acgaaagtta tagtagatag tatacacaat agagtatacc ctgaaacggt
    67741 tgcgaagtac gctaatcact ttgctactga tctagatagt ttctttaatc aataaacaca
    67801 gcatccacag attgacttag gatattgtaa gttttttgaa agctagagag aaggtctcta
    67861 aaattaaaaa acgcatagta taggatgttg aaatgatgaa ctgcccccca aaagttagac
    67921 agaaaaaatc taacttttgg ggtgttttat tatgaaatta agttatgaag ataaagttca
    67981 gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa gatttggtgt
    68041 ggatgtttct ggtctaaagt acatggtgaa attaattgac cgttatgg
//
LOCUS       DAVBOG010000004        67653 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.004, whole genome shotgun sequence.
ACCESSION   DAVBOG010000004 DAVBOG010000000
VERSION     DAVBOG010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 67653)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 67653)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..67653
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.004"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            157..1029
                     /gene="rsmA"
                     /locus_tag="VQ865_000219"
     CDS             157..1029
                     /gene="rsmA"
                     /locus_tag="VQ865_000219"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HET3134647.1"
                     /translation="MRIADYSVTKAVLERHGFTFKKSFGQNFLTDTNILQKIVDTAEI
                     DDQVNVIEIGPGIGALTEFLAERAAEVMAFEIDHRLVPILADTLRDFDNVTVVNEDIL
                     KVDLAQHIQNFKNPDLPIKVVANLPYYITTPILMHLIESGIPFSEFVVMMQKEVADRI
                     SAQPNTKAYGSLSIAVQYYMTAKVAFIVPRTVFVPAPNVDSAILKMVRRPVPAVAVED
                     ENFFFKVSKASFTHRRKTLWNNLTGYFGKTEEVKDKLTKALDQAGLSPSVRGEALSLE
                     EFASLADALKGQGL"
     gene            1719..2492
                     /locus_tag="VQ865_000220"
     CDS             1719..2492
                     /locus_tag="VQ865_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface protein"
                     /protein_id="HET3134648.1"
                     /translation="MRKKLVNSLMCAVVLSGFPIATYANEKNIGPNITVSNGQTRLSI
                     PEKNGVEVIQSEENRVVYEVKEAAKIETSDGDMVAPIVVDSRITSINNQVVQGKTVYT
                     ADLEKATFVEEGYNKLAKPTNILDHIFGIQKVHAYTQNITTHQSQFDSTYSVELYTVV
                     HWVSYDGGVQKNITKISGGVDFHERDIEIESSSVEVRQGGWYSSQQKWFHPGARSSWE
                     YSTGFSKVGPGENRVVTNYTVNLIRYGDRWSAYLQNNPW"
     gene            3085..3963
                     /gene="rsgA"
                     /locus_tag="VQ865_000221"
     CDS             3085..3963
                     /gene="rsgA"
                     /locus_tag="VQ865_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HET3134649.1"
                     /translation="MQGQIIKALAGFYYVESDGQVYQTRARGNFRKKGHTPYVGDWVD
                     FSAEENSEGYILKIHERKNSLVRPPIVNIDQAVVIMSVKEPDFNSNLLDRFLVLLEHK
                     GIHPIVYISKMDLLEDGGELDFYQQTYGDIGYDFVTSKEELLPLLTGKVTVFMGQTGV
                     GKSTLLNKIAPDLNLETGEISDSLGRGRHTTRAVSFYNLNGGKIADTPGFSSLDYEVS
                     TAEDLNQAFPEIATVSRDCKFRTCTHTHEPSCAVKPAVEEGTIAPFRFDNYLQFLSEI
                     ENRRETYKKVSKKIPK"
     gene            3974..4630
                     /locus_tag="VQ865_000222"
     CDS             3974..4630
                     /locus_tag="VQ865_000222"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HET3134650.1"
                     /translation="MSQYKIAPSILAADYANFEREIKRLEATGAEYAHIDIMDGHFVP
                     QISFGAGVVEALRPHSKMVFDCHLMVSNPEHHLEDFVRAGADIISIHVEATPHIHGAL
                     QKIRSLGVKPSVVINPGTPVEAIKHVLHLVDQVLVMTVNPGFGGQAFLPETMDKVREL
                     VALRDEKGLNFEIEVDGGIDDQTIAQSKEAGATVFVAGSYVFKGDVNERVQTLRKQLD
                     "
     gene            4593..5255
                     /locus_tag="VQ865_000223"
     CDS             4593..5255
                     /locus_tag="VQ865_000223"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000006147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HET3134651.1"
                     /translation="MSEYKLSENNWTRVAVFAGGDRGHYRTDFDGFVGVDRGSLWILE
                     EDLPLALAVGDFDSVTEEERQVIQKRAQYFVQARPEKDDTDLELALLTIFKQNPQAQV
                     TIFGALGGRIDHMLANVFLPSNPKLAPYMHQIEIEDGQNLITYCPEGISQLEPRSDYD
                     YLAFMPVRDSQLTILGAKYELTEENFFFKKVYASNEYIDREVSVTCPDGYVVVLHSKD
                     RR"
     gene            5257..6513
                     /locus_tag="VQ865_000224"
     CDS             5257..6513
                     /locus_tag="VQ865_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HET3134652.1"
                     /translation="MESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQ
                     LDYRFDQARQASQLDQKDLEVVVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDQ
                     RLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVAR
                     DVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPG
                     QGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFARDIRNKYI
                     APPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFK
                     TLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTL
                     RHIELSEGEPALDLLHFQENEEEYED"
     gene            6503..7444
                     /locus_tag="VQ865_000225"
     CDS             6503..7444
                     /locus_tag="VQ865_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exoribonuclease YhaM family protein"
                     /protein_id="HET3134653.1"
                     /translation="MKISHMKKDELFEGFYLIKSADLRQTRAGKNYLAFTFQDDSGEI
                     DGKLWDAQPHNIEAFTAGKVVHMKGRREVYNNTPQVNQITLRLPQAGEPNDPADFKVK
                     SPVDVKEIRDYMSQMIFKIENPVWQRIVRNLYTKYDKEFYSYPAAKTNHHAFETGLAY
                     HTATMVRLADAISEVYPQLNKSLLYAGIMLHDLAKVIELTGPDQTEYTVRGNLLGHIA
                     LIDSEITKTVMELGIDDTKEEVVLLRHVILSHHGLLEYGSPVRPRIMEAEIIHMIDNL
                     DASMMMMSTALALVDKGEMTNKIFAMDNRSFYKPDLD"
     gene            7711..8538
                     /gene="purR"
                     /locus_tag="VQ865_000226"
     CDS             7711..8538
                     /gene="purR"
                     /locus_tag="VQ865_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HET3134654.1"
                     /translation="MKLRRSDRMVVISNYLINNPYKLTSLNTFAEKYESAKSSISEDI
                     VIIKRAFEEIEIGHIQTVTGAGGGVIFTPSISSQDAKEMVEDLRTKLSESDRILPGGY
                     IYLSDLLSTPAILKNIGRIIAKSFMDQKIDAVMTVATKGVPLANAVANVLNVSFVIVR
                     RDLKITEGSTVSVNYVSGSSGDRIEKMFLSKRSLKAGSRVLIVDDFLKGGGTVNGMIS
                     LLREFDSELAGVAVFADNAQEEREKQFDYKSLLKVTNIDVKNQAIDVEVGNIFDEDK"
     gene            8605..9855
                     /locus_tag="VQ865_000227"
     CDS             8605..9855
                     /locus_tag="VQ865_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HET3134655.1"
                     /translation="MKTPFINREELEAIVAEFPTPFHLYDEKGIREKARAVNQAFSWN
                     KGFKEYFAVKATPTPAILKILQEEGCGVDCSSYVELLMSHKLDFLGSEIMFSSNNTPD
                     KEYAYARELGATINLDAFEDIEHLERVAGIPEIISCRYNPGGVFELGTDIMDNPGEAK
                     FGMTKDQLFEAFAILKEKGAKTFGIHSFLASNTVTHLYYPELARQLFELAVEIKEKLG
                     ISLDFINLSGGIGVNYRPDQEPNDIALIGEGVRKVYEEVLTSAGLGQVKIFTELGRFM
                     LAPHGALVTRVTHKKETYRTYLGVDASAVNLMRPAMYGAYHHISNVTHPDGPAEAVDV
                     VGSLCENNDKFAVNRELPHTEIGDLLVIHDTGAHGFSMGYQYNAKLRSAEILYTEEGK
                     ARQIRRAERPEDYFATLYGFDFEE"
     gene            9981..10775
                     /gene="pflA"
                     /locus_tag="VQ865_000228"
     CDS             9981..10775
                     /gene="pflA"
                     /locus_tag="VQ865_000228"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001288284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HET3134656.1"
                     /translation="MSEETIDYGQVTGMVHSTESFGSVDGPGIRFIVFLQGCHMRCQY
                     CHNPDTWAMESNKSRERTVDDVLTEALRYRGFWGNKGGITVSGGEALLQIDFLIALFT
                     KAKEQGIHCTLDTCALPFRNKPRYLEKFDKLMAVTDLVLLDIKEINEEQHKIVTSQTN
                     KNILACAQYLSDIGKPVWIRHVLVPGLTDRDDDLIELGKFVKTLKNVDKFEILPYHTM
                     GEFKWRELGIPYSLEGVKPPTADRVKNAKKLMDTESYQDYMKRVHG"
     gene            complement(10850..11776)
                     /gene="yidC"
                     /locus_tag="VQ865_000229"
     CDS             complement(10850..11776)
                     /gene="yidC"
                     /locus_tag="VQ865_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3134657.1"
                     /translation="MKSIKRFAFSAMGVAMLLVLTGCVNVDKTTGQPTGFIWNTIGAP
                     MAEAIKYFATDKGLGFGVAIIIVTIIVRLIILPLGIYQSWKATLHSEKMNALKHVLEP
                     HQTRLKEATTQEEKLEAQQALFAAQKEHGISMFGGVGCFPILLQMPFFSAIYFAAQHT
                     EGVAQASYLGIPLGSPSMILVACAGVLYYLQSLLSLHGVEDEMQREQIKKMIYMSPLM
                     IVVFSLFSPASVTLYWVVGGFMMILQQFIVNYIVRPKLRKKVREELAKNPPKASAFSK
                     PSGRKDVTPEQPTAITSKKKHKNRNAGKQRSR"
     gene            complement(11854..12132)
                     /locus_tag="VQ865_000230"
     CDS             complement(11854..12132)
                     /locus_tag="VQ865_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HET3134658.1"
                     /translation="MQKVRMIAQGRVQGVGFRWGVYSLALEIGGITGRVWNNDDGTVE
                     ILAQADSSAIMAKFIQEIRKGPTPFSKVSYLDVKLSNFPPYSDFKIAN"
     gene            12166..12906
                     /locus_tag="VQ865_000231"
     CDS             12166..12906
                     /locus_tag="VQ865_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HET3134659.1"
                     /translation="MTIITSKANSVVKNAKKLRQKKYRKSAYLIEGWHLFEEAVQAGV
                     TIEKIFALENYRDQLATFSQTVWVSEDILLDLADSQTPQGIVAVVQKEEVGQADLSQG
                     KFLFLEDVQDPGNVGTIIRTADAAGFTGVIVSDKSADIYSLKTLRSMQGSHFHLPIYR
                     MTSPALLDETKKVAIPVLATTLSKDSVDYRELPSIENFVLVMGNEGQGISPLMAESAD
                     QLVHISMKGQAESLNVAVAAGILIFHLS"
     gene            12962..13645
                     /locus_tag="VQ865_000232"
     CDS             12962..13645
                     /locus_tag="VQ865_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HET3134660.1"
                     /translation="MNHTIIHDRAGLNQFYAKVYAFVGLGIGLSALVSGLMLTVFQSQ
                     LVYLLMQGRLWLTIATFAELALVFVASSMASRNSPAALPVFLLYSVLNGFTLSFVVAF
                     YTPGTVLSAFVSSALLFFVMAAVGIFTKKDLSGIGRAMMAALIGLLIAMVVNIFLASG
                     FFDYMISVAMVLVFSGLIAWDNQKIRLAYEQSQGRVATGWVVSMALSIYLDFINLFLS
                     ILRIFGRND"
     gene            13756..14748
                     /locus_tag="VQ865_000233"
     CDS             13756..14748
                     /locus_tag="VQ865_000233"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HET3134661.1"
                     /translation="MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGM
                     QDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPD
                     EDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESI
                     LPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDY
                     DDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLEL
                     EWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL"
     gene            14813..15352
                     /gene="rsmD"
                     /locus_tag="VQ865_000234"
     CDS             14813..15352
                     /gene="rsmD"
                     /locus_tag="VQ865_000234"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006147838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HET3134662.1"
                     /translation="MKIVSGIYGGRPLKTLEGKTTRPTSDKVRGAIFNMIGPYFEGGR
                     VLDLYAGSGGLSIEAVSRGMSSAVLVERDRKAQTIVAENIQMTKEVGKFQLLKMDAER
                     ALEQVSGEFDLVFLDPPYAKEQIVADIEKMAKRELFSEDVMVVCETDKAVELPEEIAC
                     LGIWKEKIYGISKVTVYVR"
     gene            15342..15860
                     /gene="coaD"
                     /locus_tag="VQ865_000235"
     CDS             15342..15860
                     /gene="coaD"
                     /locus_tag="VQ865_000235"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HET3134663.1"
                     /translation="MSDKIGLFTGSFDPMTNGHLDIIERASRLFDKLYVGIFFNPHKQ
                     GFLPLENRKRGLEKALGHLENVEVVASHDELVVDVAKRLGATFLVRGLRNAADLQYEA
                     SFDYYNHQLSSDIETIYLHSRPEHLYISSSGVRELLKFGQDIACHVPESILEEIRNEK
                     KRLDGPYTSLRP"
     gene            15827..16852
                     /locus_tag="VQ865_000236"
     CDS             15827..16852
                     /locus_tag="VQ865_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HET3134664.1"
                     /translation="MRWPLYVIAALIVTFLAFVVPLPYYIEVPGGSEDIRQVLKVNDT
                     EDKEAGAYQFVTVGVQHATLAHMIYAWLTPFTDIRSAQETTGGSSDVEFMRINQFYMQ
                     TSQNMAKYQGLKTAGKDIELKYFGVYVLNVTDNSTFKGILNISDTVTAVNDQTFDSSK
                     DLIDYVSSQKLGDSVKVTYEEDGQTKSAEGKIITLENGKNGIGIGLIDRTEVISNVPI
                     SFSTAGIGGPSAGLMFSLAIYTQIAHPDLRNGRIVAGTGTIDRDGNVGDIGGIDKKVV
                     ASARAGAAIFFAPDNPVSEEEQKAHLDAKNNYQTALEAAKTIKTDMKIVPVKTLQDAI
                     DYLKNNP"
     gene            16910..17140
                     /locus_tag="VQ865_000237"
     CDS             16910..17140
                     /locus_tag="VQ865_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014017351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HET3134665.1"
                     /translation="MVQLLFTLSSHMLFIYVSFYLLKDLVRWEKVLKVTDDNTRKVRL
                     LVAFFSIVIGYILSSFFISLYHLWQEALRGLL"
     gene            17164..18447
                     /gene="murA"
                     /locus_tag="VQ865_000238"
     CDS             17164..18447
                     /gene="murA"
                     /locus_tag="VQ865_000238"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3134666.1"
                     /translation="MDKIVVQGGDNRLVGSVTIEGAKNAVLPLLAATILASEGKTVLQ
                     NVPILSDVFIMNQVVGGLNAKVDFDEEAHLVKVDATGDITEEAPYKYVSKMRASIVVL
                     GPILARVGHAKVSMPGGCTIGSRPIDLHLKGLEAMGVKISQTAGYIEAKAERLHGAHI
                     YMDFPSVGATQNLMMAATLADGVTVIENAAREPEIVDLAILLNEMGAKVKGAGTETIT
                     ITGVEKLHGTTHNVVQDRIEAGTFMVAAAMTGGDVLIRDAVWEHNRPLIAKLLEMGVE
                     VIEEDEGIRVRSQLENLKAVHVKTLPHPGFPTDMQAQFTALMTVAKGESTMVETVFEN
                     RFQHLEEMRRMGLHSEIIRDTARIVGGQPLQGAEVLSTDLRASAALILTGLVAQGETV
                     VGKLVHLDRGYYGFHEKLAQLGAKIQRIEASDEDE"
     gene            18440..18628
                     /locus_tag="VQ865_000239"
     CDS             18440..18628
                     /locus_tag="VQ865_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3134667.1"
                     /translation="MNKKSSYVINRLLLVIIVLILGTLALGIGLMVGYGILGKGQDPW
                     AILSPAKWQELIHKFTGN"
     gene            18667..19491
                     /gene="endA"
                     /locus_tag="VQ865_000240"
     CDS             18667..19491
                     /gene="endA"
                     /locus_tag="VQ865_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-entry nuclease EndA"
                     /protein_id="HET3134668.1"
                     /translation="MNKKTRQTLIGLLVLLLLSTGSYYIKQMQSAPNSPKTNLSQKKQ
                     ASEAPSQALAESVLTDAVKSQIKGSLEWNGSGAFIVNGNKTNLDAKVSSKPYADNKTK
                     TVGKETVPTVANALLSKATRQYKNRKETGNGSTSWTPPGWHQVKNLKGSYTHAVDRGH
                     LLGYALIGGLDGFDASTSNPKNIAVQTAWANQAQAEYSTGQNYYESKVRKALDQNKRV
                     RYRVTLYYASNEDLVPSASQIEAKSSDGELEFNVLVPNVQKGLQLDYRTGEVTVTQ"
     gene            19782..21113
                     /locus_tag="VQ865_000241"
     CDS             19782..21113
                     /locus_tag="VQ865_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HET3134669.1"
                     /translation="MEDPSSQNLLLQFVLLFILTVLNAFFSATEMAMVSLNRARVEQK
                     AEEGDRRYIRLLKVLENPNHFLSTIQVGITLITILSGASLTDTLGRVIASWLGNGETA
                     QAVATFLSLAFLTYISIVFGELYPKRIALNLKDALAIRTAPIIIGIGKLVSPFVWLLA
                     ASTNFLSHLTPMSFDDADEKMTRDEIAYMLTNSEETLDADEIEMLQGVFSLDELMARE
                     VMVPRTDAFMVDIQDDSQAIIQSILKQNYSRIPVYDGDKDNVIGIIHTKSLLKAGFVD
                     GFDNIVWKRILQDPLFVPETIFVDDLLKELRNTQRQMAILLDEYGGMAGLVTLEDLLE
                     EIVGEIDDETDKAAIDVHQIGEDTYIVQGTMTLNDFNNYFDVELESDDVDTIAGYYLT
                     GVGTIPTTEKLSYELVSQNKQFILTNDKVKNGRVTKVKVQITEVEIEEETE"
     gene            complement(21311..21381)
                     /locus_tag="VQ865_000242"
     tRNA            complement(21311..21381)
                     /locus_tag="VQ865_000242"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21347..21349),aa:Cys,seq:gca)
     gene            21797..25408
                     /gene="rpoB"
                     /locus_tag="VQ865_000243"
     CDS             21797..25408
                     /gene="rpoB"
                     /locus_tag="VQ865_000243"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HET3134670.1"
                     /translation="MAGHDVQYGKHRTRRSFSRIKEVLDLPNLIEIQTDSFKAFLDHG
                     LKEVFEDVLPISNFTDTMELEFVGYEIKEPKYTLEEARIHDASYSAPIFVTFRLINKE
                     TGEIKTQEVFFGDFPIMTEMGTFIINGGERIIVSQLVRSPGVYFNDKVDKNGKVGYGS
                     TVIPNRGAWLELESDSKDITYTRIDRTRKIPFTTLVRALGFSGDDEIFDIFGDSELVR
                     NTVEKDIHKNPMDSRTDEALKEIYERLRPGEPKTAESSRSLLVARFFDPRRYDLAAVG
                     RYKINKKLNVKTRLLNQTIAEPLVDPETGEILVEAGTIMTRSVIESIESHLDGDLNKI
                     VYIPNDAAVVTEPVVLQKFKVVAPTDPDRVVTIIGNANPDDKVRTVTPADILAEMSYF
                     LNLAEGLGRVDDIDHLGNRRIRAVGELLANQVRLGLSRMERNVRERMSVQDNEVLTPQ
                     QIINIRPVTAAVKEFFGSSQLSQFMDQHNPLSELSHKRRLSALGPGGLTRDRAGYEVR
                     DVHYTHYGRMCPIETPEGPNIGLINNLSSYGHLNKYGFVQTPYRKVDRETGVVTNEIV
                     WLTADEEDEYTVAQANSRLNEDGTFAEKIVMGRHQGVNQEYPANIVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPYVGTGMEYQAAHDSGAAVIAQY
                     DGKVTYADADKVEVRREDGSLDVYHIQKFRRSNSGTAYNQRTLVKVGDVVEKGDFIAD
                     GPSMENGEMALGQNPIVAYMTWEGYNFEDAVIMSERLVKDDVYTSVHLEEYESETRDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVKEGDILVGKVTPKGEKDLSAEERL
                     LHAIFGDKSREVRDTSLRVPHGADGVVRDVKIFTRVNGDELQSGVNMLVRVYIAQKRK
                     IKVGDKMAGRHGNKGVVSRIVPVEDMPYLPDGTPVDIMLNPLGVPSRMNIGQVMELHL
                     GMAARTLGIHIATPVFDGASSEDLWSTVKEAGMDSDAKTILYDGRTGEPFDNRVSVGV
                     MYMIKLHHMVDDKLHARSVGPYSTVTQQPLGGKAQFGGQRFGEMEVWALEAYGASNVL
                     QEILTYKSDDINGRLKAYEAITKGKPIPKPGVPESFRVLVKELQSLGLDMRVLDEDDQ
                     EVELRDLDEGMDEDVIHVDDLEKAREKAAQEAKAAFEAEEAEKATKAEATEEAAEQE"
     gene            25441..29118
                     /gene="rpoC"
                     /locus_tag="VQ865_000244"
     CDS             25441..29118
                     /gene="rpoC"
                     /locus_tag="VQ865_000244"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HET3134671.1"
                     /translation="MVDVNRFKSMQITLASPSKVRSWSYGEVKKPETINYRTLKPERE
                     GLFDEVIFGPTKDWECACGKYKRIRYRGIVCDRCGVEVTRTKVRRERMGHIELKAPVS
                     HIWYFKGIPSRMGLTLDMSPRALEEVIYFAAYVVIDPKDTPLEHKSIMTEREYRERLR
                     EYGYGSFVAKMGAEAIQDLLKQVDLEKEIAELKEELKTATGQKRVKAIRRLDVLDAFY
                     KSGNKPEWMILNILPVIPPDLRPMLQLDGGRFASSDLNDLYRRVINRNNRLARLLELN
                     APGIIVQNEKRMLQEAVDALIDNGRRGRPITGPGSRPLKSLSHMLKGKQGRFRQNLLG
                     KRVDFSGRSVIAVGPTLKMYQCGVPREMAIELFKPFVMREIVARDIVQNVKAAKRLVE
                     RGDERIWDILEEVIKEHPVLLNRAPTLHRLGIQAFEPVLIDGKALRLHPLVCEAYNAD
                     FDGDQMAIHVPLSEEAQAEARILMLAAEHILNPKDGKPVVTPSQDMVLGNYYLTMEEA
                     GREGEGMVFKDRDEAVMAYRNGYVHLHSRVGIATDSLNKPWTEEQRHKVLLTTVGKIL
                     FNDIMPEGLPYLQEPNNANLTEGVPAKYFLPLGGDIKEAISNLELNPPFKKKNLGNII
                     AEIFKRFRTTETSALLDRMKNLGYHHSTLAGLTVGIADIPVVDDKTEIIEESHKRVEQ
                     ITKQFRRGMITDDERYNAVTAEWRAAREKLEKRLIANQDPKNPIVMMMDSGARGNISN
                     FSQLAGMRGLMAAPNGRIMELPILSNFREGLSVLEMFFSTHGARKGMTDTALKTADSG
                     YLTRRLVDVAQDVIIREDDCGTDRGLLIRSIAEGKEMIESLEERLNGRYTKKTVKHPE
                     TGAVIIGPNELITEDKAREIVNAGVEEVTIRSVFTCNTRHGVCRHCYGINLATGDAVE
                     VGEAVGTIAAQSIGEPGTQLTMRTFHTGGVASNTDITQGLPRVQEIFEARNPKGEAVI
                     TEVKGQVTAIEEDASTRTKKVFVKGETGEGEYVVPFTARMRVEVGGQVARGAALTEGS
                     IQPKRLLAVRDVLSVETYLLGEVQKVYRSQGVEIGDKHIEVMVRQMIRKVRVMDPGDT
                     DLLMGTLMDINDFTDANKDVLIAGGVPATGRPVLMGITKASLETNSFLSAASFQETTR
                     VLTDAAIRGKKDHLLGLKENVIIGKIIPAGTGMARYRNLEPYAVNEEEYLNPPVEEEG
                     NEETTEVVVDTAVETVEETVE"
     gene            29229..29642
                     /gene="ndk"
                     /locus_tag="VQ865_000245"
     CDS             29229..29642
                     /gene="ndk"
                     /locus_tag="VQ865_000245"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000438285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HET3134672.1"
                     /translation="MEQTFFIIKPDGVKRGLVGEVLKRIEQRGFTIEKLEFRSQVSEE
                     LIDQHYQDLVGQSFYPPIREFMTSGPVLVGVISGPKVIETWRTMMGATRPEEALPGTI
                     RGDFAKAAGENEVIQNVVHGSDSEESAKREIALWF"
     gene            complement(30151..30429)
                     /locus_tag="VQ865_000246"
     CDS             complement(30151..30429)
                     /locus_tag="VQ865_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComA"
                     /protein_id="HET3134673.1"
                     /translation="MKKFDNYIVEKPCDSNSDKLQKILIIENLVDDILQFPLRINNSV
                     GEIFLLQPFQKKTIFIPCYFEEDIVKVKDDDKVEWNLLEFQKFRAFLA"
     gene            complement(30570..31202)
                     /locus_tag="VQ865_000247"
     CDS             complement(30570..31202)
                     /locus_tag="VQ865_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134674.1"
                     /translation="MIELKQVSKSFGERELFSNLSMTFEAGKVYALIGSSGSGKTTLM
                     NMIGKLEPYDGTIFYRGKDLANYKSSDFFRHELGYLFQNFGLIENQSIEENLKLGLIG
                     QKLSRSEQRLRQKQALEQVGLTYLDLDKRIFELSGGESQRVALAKVILKNPPFILADE
                     PTASIDPATSQLIMEILLSLRDDNRLIIIATHNPAIWEMADEVFTMDRLK"
     gene            complement(31204..33219)
                     /locus_tag="VQ865_000248"
     CDS             complement(31204..33219)
                     /locus_tag="VQ865_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3134675.1"
                     /translation="MKKLFILISNLLASLFFVWVFTIWTDTYVSYYYPNVVVHDSSPE
                     TTFQHVATRLEKLAEETDSFIAIQHQDSNSEGTTVFSYTTFGDGKLPDGLQEKKLEDA
                     QSSSVETNYFVFDGHLDIHLLREELSQLGLTNMNLTIPSKLSTLMAIFSNGFQLISLL
                     IFILTFVALTLISQISQLRSSGIRLISGEKRWSIFLRPVGEDLKGIAVGFSLAGVLAI
                     LMQKILSLPTQSLMTIGAGLLSYNLILLSISLFFAQLFAVGIKKIHLMQIIKGQVPVR
                     GIISLILIGQLLAIIIVTLGIGSSLKYSQAWQQHRIGQEAWSQERQLITLSISREGTS
                     PGFDEQAQRKLRTWYQLMDLAVSEQKAFLSRHQLIDRTLQNGMASSKNLITSTEWHDY
                     NPNGNVLIVTPQYLERQNIPVDTTIEQKMNHLYVGEFVLLLPEHLRSEEEHYKSVFED
                     DLTSRMSSQDERQQMTATVGYLESGQDRFVYNTTPISYQQFLKDPIIIVITPQSTGPQ
                     SILFWIDAVQNYVLFNQLSDAQELIQRQGIENWVSEMQTGYHNYITLLDNIQRERWVM
                     LAGAGLGIATSILLFNTMNRLYFEEFRRAIFIKRIAGLRFLEIHRTYLFAQLGVFLLG
                     FVASVFLQVEIGVAFLVLLLFTGLSLLQLHVQMQKENKMSMLVLKGG"
     gene            33723..34586
                     /locus_tag="VQ865_000249"
     CDS             33723..34586
                     /locus_tag="VQ865_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3134676.1"
                     /translation="MNTLAEKFRLKRKELRLSQQTLAEGICEQSQISKIERGHFIPSA
                     DLLFKLSQRLEVPLDYFFNEQIEIKSNLSNFKQLSARLLDDRNYDDLEYIYRIEIERS
                     TFLTLEDRTYLEWIKAIIDFYQYDSKCEAISSLENILLKVSSNTLIYLKALNTLSNFY
                     SLVGREQEYEANYSHLIELYQTKNLDHQEFLFGYIRVRYNYAHYLVSKEKYNEAIQEA
                     LETIELCKQRQTSYQLAPLLILVGNAGAKFLDREQVKNYYIEARELCKIYNNPLMLMK
                     IENYLKELDTV"
     gene            34969..35589
                     /locus_tag="VQ865_000250"
     CDS             34969..35589
                     /locus_tag="VQ865_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000839915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134677.1"
                     /translation="MKSMRILFLLALIQISLSSCFLWKECILSFKQSTAFFIGSMVFV
                     SGICAGVNYLYTRKQEVHSVLASKKSVKLFYSMLLLINLLGAVLVLSDNLFIKNTLQQ
                     ELVDFLLPSFFFLFGLDLLIFLPLKKYVRDFLAMLDRKKTVLVTILATLLFLRNPMTI
                     VSLLIYIGLGLFFAAYLVPNSVKKEVSFYGHIFRDLVLVIVTLIFF"
     gene            35675..36118
                     /gene="tsaE"
                     /locus_tag="VQ865_000251"
     CDS             35675..36118
                     /gene="tsaE"
                     /locus_tag="VQ865_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HET3134678.1"
                     /translation="MYIKNEEELQALGERLGHLLAKNDVLILIGELGAGKTTFTKGLA
                     KGLQISQMIKSPTYTIVREYEGRLPLYHLDVYRIEGDADSIDLDEFIFGGGVTVIEWG
                     NLLGDALPDAYLELEILKEADGRRLNFQAKGLRAEKLSEELQYGV"
     gene            36108..36626
                     /locus_tag="VQ865_000252"
     CDS             36108..36626
                     /locus_tag="VQ865_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134679.1"
                     /translation="MEYELLIREAEPKDAAELVAFLNRVSLETDFTSLDGDGILLTSE
                     EMEIFLNKQASSDNQITLLAFLNGKITGIVNITADQRKRVRHIGDLFIVIGKRYWNNG
                     LGSLLLEEAIEWAQASGILRRLQLTVQTRNQAAVHLYQKHGFVIEGSQERGAYIEEGK
                     FIDVYLMGKLIG"
     gene            36634..37650
                     /locus_tag="VQ865_000253"
     CDS             36634..37650
                     /locus_tag="VQ865_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3134680.1"
                     /translation="MVKKIIGMVLALLSVTVVGVGVFAYTIYQQGTETLAKTYKKIGE
                     ETKVIEATEPLTILLMGVDTGNVERTETWVGRSDSMILMTVNPKTKKTTMMSLERDIL
                     TRIESGNGQAHEAKLNSAYADGGAELAIETIQKMMNIHIDRYVMVNMRGLQKLVDAVG
                     GITVNNILGFPISISDQEEFNTISIGVGEQHIGGEEALVYARMRYQDPEGDYGRQKRQ
                     REVIQKVMEKALSLNSIGHYQEILKALSDNMQTNIDLSAKSIPNLLGYKDSFKTIETQ
                     QLQGEGEILQGVSYQIVSRAHMLEMQNILRRSLGQEEVTQLETNAVLFEDLFGRAPVG
                     DEDN"
     gene            37735..38991
                     /locus_tag="VQ865_000254"
     CDS             37735..38991
                     /locus_tag="VQ865_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HET3134681.1"
                     /translation="MKAEIIAVGTEILTGQIVNTNAQFLSEKLAEIGVDVYFQTAVGD
                     NEVRLLSLLEIASQRSSLVILTGGLGPTEDDLTKQTLAKFLGKALVFDPQAQEKLDIF
                     FALRPDYARTPNNERQAQIVEGAIPLPNETGLAVGGKLEVDGVTYVVLPGPPSELKPM
                     VLNQLLPKLMTGSKLYSRVLRFFGIGESQLVTILADLIDNQIDPTLAPYAKTGEVTLR
                     LSTKASSQEEANQALDILENQILDCQTFEGISLRDFCYGYGEETSLASIVVEELKRQG
                     KTIAAAESLTAGLFQATVANFSGVSSIFKGGFVTYSLEEKSRMLDIPAKNLEEHGVVS
                     EFTAQKMAEQARSKTQSDFGISLTGVAGPDSLEGHPVGTVFIGLAQEQGTEVIKVNIG
                     GRSRADVRHIAVMHAFNLVRKALLSD"
     gene            39046..40212
                     /gene="recA"
                     /locus_tag="VQ865_000255"
     CDS             39046..40212
                     /gene="recA"
                     /locus_tag="VQ865_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HET3134682.1"
                     /translation="MAKKPKKLEEISKKFGAEREKALNDALKLIEKDFGKGSIMRLGE
                     RAEQKVQVMSSGSLALDIALGSGGYPKGRIIEIYGPESSGKTTVALHAVAQAQKEGGI
                     AAFIDAEHALDPAYAAALGVNIDELLLSQPDSGEQGLEIAGKLIDSGAVDLVVVDSVA
                     ALVPRAEIDGDIGDSHVGLQARMMSQAMRKLGASINKTKTIAIFINQLREKVGVMFGN
                     PETTPGGRALKFYASVRLDVRGNTQIKGTGDQKETNVGKETKIKVVKNKVAPPFKEAV
                     VEIMYGEGISKTGELLKIASDLDIIKKAGAWYSYKDEKIGQGSENAKKYLAEHPEIFD
                     EIDKQVRSKFGLIDGEEVSEQDTENKKDEPKKEEAVNEEVTLDLGDELEIEIEE"
     gene            40519..41889
                     /locus_tag="VQ865_000256"
     CDS             40519..41889
                     /locus_tag="VQ865_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3134683.1"
                     /translation="MNKKRTVDLIHGSILPSLLSFTFPILLSNIFQQLYNTADVLIVG
                     RFLGQESLAAVGATTAIFDLIVGFTLGVGNGMGIVIARYYGARNFTKIKEAVAATWIL
                     GALLSILVMLLGFLGLYPLLQYLDTPAEILPQSYQYISMIVTCVGVSFAYNLFAGLLR
                     SIGDSLAALGFLIFSALVNVVLDLYFITQLHLGVQSAGLATIISQGLSAVLCFYYIRK
                     SVPELLPRFKHFKWDKSLYADLLEQGLAMGLMSSIVSIGSVILQFSVNTFGAVIISAQ
                     TAARRIMTFALLPMTAISASMTTFASQNLGAKRPDRIVQGLRIGSRLSISWAVFVCIF
                     LFFASPALVSFLASSTDGYLIENGSLYLQISSAFYPILSLLLIYRNCLQGLGQKILPL
                     VSSFIELIGKIVFVVLIIPWAGYKGVILCEPLIWVAMTVQLYFSLFRHPLIKEGKAIL
                     ATKVQS"
     gene            42265..43221
                     /gene="lytA"
                     /locus_tag="VQ865_000257"
     CDS             42265..43221
                     /gene="lytA"
                     /locus_tag="VQ865_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase LytA"
                     /protein_id="HET3134684.1"
                     /translation="MEINVSKLRTDLPQVGVQPYRQVHAHSTGNPHSTVQNEADYHWR
                     KDPELGFFSHIVGNGCIMQVGPVDNGAWDVGGGWNAETYAAVELIESHSTKEEFMTDY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLAKWGIS
                     REQFKYDIENGLTIETGWQKNDTGYWYVHSDGSYPKDKFEKINGTWYYFDSSGYMLAD
                     RWRKHTDGNWYWFDNSGEMATGWKKIADKWYYFNEEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPEFTVEPDGLITVK"
     gene            43580..43741
                     /locus_tag="VQ865_000258"
     CDS             43580..43741
                     /locus_tag="VQ865_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3134685.1"
                     /translation="MYVINVCDVGKRIKELRISSNLTQDKIAEYLSLNQSMIAKMEKG
                     ERNITNGFK"
     gene            43728..43934
                     /locus_tag="VQ865_000259"
     CDS             43728..43934
                     /locus_tag="VQ865_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134686.1"
                     /translation="MDLSNKASNLRKKLGADGESPIDIFKLVQKIENLTLVFYGLGKN
                     ISGVCYKGTQFSLIAVNSDMPLER"
     gene            43980..44339
                     /locus_tag="VQ865_000260"
     CDS             43980..44339
                     /locus_tag="VQ865_000260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134687.1"
                     /translation="MKKSSVSLILIGEGDETERKADQFASYFLIFPSSLYRMVEEIRE
                     NANRTHLEVEDIIKLGQFYGISHKAMLYRLRNDGYLDAEEIKNMDISVIETASRLGYD
                     TSLYRPLSESKKEMALG"
     gene            44468..44893
                     /locus_tag="VQ865_000261"
     CDS             44468..44893
                     /locus_tag="VQ865_000261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000204059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134688.1"
                     /translation="MTSRVFIDADCISVFLWVGIEHLLEKLYLGKIVIPQEVYDEINI
                     PTIPHLKSRIDQLVAKGSAEIVSIDIGTEEYALYRDLTRNHDSNKIIGKGEGASISLA
                     KKHNGILGSNNLRDVKPYVEEFSLEHMTTGDILIEAFKA"
     gene            45291..45875
                     /locus_tag="VQ865_000262"
     CDS             45291..45875
                     /locus_tag="VQ865_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001101186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134689.1"
                     /translation="MNVKKIMSIFQSFYVDVSIEELTLTLPISFVKKFEYTQMTFHKE
                     SFLLIKEKRRGSLSSFVTQARTMGDKANMDVVLVFSKLSDGEKKQLLQARVPFVDFKG
                     NLFFPTLGLVLNANDTEVPKELIPSEQLTWIAFLLPDGDIKQIKSVSNLLYGGAYALS
                     HSTFLAETDENTSYVIWQRKFNQLSLPLSQHVLK"
     gene            45879..46076
                     /locus_tag="VQ865_000263"
     CDS             45879..46076
                     /locus_tag="VQ865_000263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134690.1"
                     /translation="MLEIWKYRPFVSEFWNDFKNNHDKQFVDPISLYLTLKDDDDPRI
                     EEESEALENMILQYLGEDDAS"
     gene            46066..46617
                     /locus_tag="VQ865_000264"
     CDS             46066..46617
                     /locus_tag="VQ865_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134691.1"
                     /translation="MPANTKVIFQEMFADFQNYYVLIGGTATSIVLDSQGFKSRTTKD
                     YDMVIIDEVKNKEFYTTLNHFLELGEYQGSQKDEKAQLFRFTTTNSEFPSMIELFSIL
                     PEYPLKKDGREIPLHFDQDASLSALLLDEDYYNILVHEKETIQGYSVLSNCGLYSSKI
                     SSNHVSFHLQPQNSVLSSLQLAS"
     gene            46676..46936
                     /locus_tag="VQ865_000265"
     CDS             46676..46936
                     /locus_tag="VQ865_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134692.1"
                     /translation="MRERSATGAQGLSKSIKKHLNDLTRLTASLLGDEKLSAITSSSA
                     VKADMHRFVIELELVKSTILQNDDISLDQNEIFEILKNFFDG"
     gene            complement(47701..48100)
                     /locus_tag="VQ865_000266"
                     /pseudo
     CDS             complement(47701..48100)
                     /locus_tag="VQ865_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            48225..48683
                     /locus_tag="VQ865_000267"
     CDS             48225..48683
                     /locus_tag="VQ865_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000186958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HET3134693.1"
                     /translation="MTPEEMYLTERLDVQIAHFLKKSVQHRRRYKVLKITEIVAGFLI
                     AVFCAIPMPGDRYRLISVALSSLGLLCEGIINLYNAKENWISYQKTAQLLEKEKFLYQ
                     CQTEKYAGKTKAFALFVKTCEGLISEEINQWESIQSKEVAASADAPVKKE"
     gene            48696..49304
                     /locus_tag="VQ865_000268"
     CDS             48696..49304
                     /locus_tag="VQ865_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134694.1"
                     /translation="MSQSSYLSPLLWLKKEADKEKMSATQCQIFFFYYQMFELLFARE
                     SDMKDLCLGTKGFYFSQLEKNLLSGVSRFLKNLEGKVTLKANQEVSARKALFLALTTS
                     QSDWQELAPVFDFYQTIGRLENPSLLSSQDRQHLMWIYQSALEKDYIVKVIGDKHFVL
                     KRQDATKLTARQTQTLEILSQSEDLVNPVYVTLGEKGVLLLD"
     gene            49375..49707
                     /locus_tag="VQ865_000269"
     CDS             49375..49707
                     /locus_tag="VQ865_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134695.1"
                     /translation="MYICIDNSMTKNKELVKNQTFKPALLTRRLVKNFMIEEPDLARN
                     PFTRPTLIDLDKVFMLDNTVIPTSYLARRRRNVSEELYEEILDHLVQPRLISLNKSEF
                     MQLNPGTY"
     gene            49718..51133
                     /gene="ply"
                     /locus_tag="VQ865_000270"
     CDS             49718..51133
                     /gene="ply"
                     /locus_tag="VQ865_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cholesterol-dependent cytolysin pneumolysin"
                     /protein_id="HET3134696.1"
                     /translation="MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFV
                     VIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDETLLENNPTLLAVDRAPMTYSID
                     LPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ
                     LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTV
                     TVEDLKQRGISAERPLVYISSVAYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQT
                     EWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRFTADHPGLPISYTTS
                     FLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVL
                     TPKAWDRNGQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRK
                     RTISIWGTTLYPQVEDKVEND"
     gene            52014..52730
                     /locus_tag="VQ865_000271"
     CDS             52014..52730
                     /locus_tag="VQ865_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3134697.1"
                     /translation="MGRKWANIVAKKTAKDGANSKVYAKFGVEIYVAAKKGDPDPESN
                     SALKFVIDRAKQAQVPKHIIDKAIDKAKGNTDETFTEGRYEGFGPNGSMLIVDTLTSN
                     VNRTAANVRAAFGKNGGNMGASGSVSYLFDNKGVIVFGGEDADAVFEQLLEADVDVDD
                     VEAQEGTITVYTAPTDLHKAIVALRESGIEEFQVTELEMIPQSEVELSGEDLETFEKL
                     YSVLEDDEDVQKIYTNVDGF"
     gene            52854..53323
                     /locus_tag="VQ865_000272"
                     /pseudo
     CDS             52854..53323
                     /locus_tag="VQ865_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360543.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
     gene            53340..54161
                     /locus_tag="VQ865_000273"
                     /pseudo
     CDS             53340..54161
                     /locus_tag="VQ865_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601671.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            54168..55139
                     /locus_tag="VQ865_000274"
     CDS             54168..55139
                     /locus_tag="VQ865_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000506433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3134698.1"
                     /translation="MDFLLMGALFIVLPRTMVSAKRINQVLDLHSSIQNPAQVQLTDE
                     NFKGQVEFKDVTFRYAANSEAVIEHVSFKAETGQTVAFIGSIGSGKSTLVNLIPRFYD
                     VSAGEILVDGVNVQDYDFSATAHAGQRVAIVGPTGAGKTTIVNLLMKFYEIDKGSIRI
                     DGVDTKAMTRSEVHDAFSMVLQDTWLFEGTIRDNLIYNQIGISDERMMEASKAVGIHH
                     FIMTLPDGYDTILDDTVTLSVGQKQLLTIARALLKDAPLLILDEATSSVDTRTEELIQ
                     KAMDRLMEGRTSFVIAHRLSTIRNADLILVMKDGNIIEQGNYEELMV"
     gene            55265..55627
                     /locus_tag="VQ865_000275"
     CDS             55265..55627
                     /locus_tag="VQ865_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HET3134699.1"
                     /translation="MSQKLYNMKFAAVYLALIAKVERKGGKAESVHQVTSWLTGYEVS
                     DVLTCLDRDVTYGDFFRQAPYYVPERIAITGKICGVRIEEIDDPLMQEIRRLDKLVDW
                     LAKGKTSQQVLEKYEKHK"
     gene            55624..56127
                     /locus_tag="VQ865_000276"
     CDS             55624..56127
                     /locus_tag="VQ865_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3134700.1"
                     /translation="MKNYQEWYRNIRSRLTSRPILLFLLRSFNRLMTVAMPLVYLILL
                     VTTYLQLGLGQQVGVYVLIPASGFVALSLFRKKINHPRPYETWDICPLLDKDSSGRSM
                     PSRHVFSATIISMACLHASLPIGLVCLIFSALLGLVRVLGGVHYPKDVLVGYACGLVW
                     GFLFFLF"
     gene            56241..56687
                     /locus_tag="VQ865_000277"
     CDS             56241..56687
                     /locus_tag="VQ865_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3134701.1"
                     /translation="MKLRIEIDGNLEETEIVIKTPTLTDEIADLQRLLQESKSPRLIF
                     YKGTGEYYLDLSEILFFETEGSKIYAHTQKNAYEVRLKLYELEAILPRYFSRVSKSTI
                     VNIRQIYSVDKSFSGTGTISFYQTHKEVHVSRHYQSLLKENLRNMR"
     gene            56692..57366
                     /locus_tag="VQ865_000278"
     CDS             56692..57366
                     /locus_tag="VQ865_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134702.1"
                     /translation="MKKKAFGIVLLVLAALILVQGNFGIPSLGGHIWPLIGIAFFAYQ
                     SVGALLRRHLTSASFTALVALMIANHFYGILPIPNQTLIWAGVLIVLGVNMLTHSNRT
                     WNGKKWWYDGEKNILIDKEVAFGTGTFYKQDQELVEDQVEVGFGNAKIYYDNAEMLGD
                     FATLNIEVAFGNATVYVPQHWRVDLKVETSFGAAKADAPVAPTSKTLIIRGDVAFGKL
                     EIVYAK"
     gene            57527..57718
                     /locus_tag="VQ865_000279"
     CDS             57527..57718
                     /locus_tag="VQ865_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-binding protein"
                     /protein_id="HET3134703.1"
                     /translation="MYYSVDDVVSNAFKKRMILDSFFAFNCSGTMKVSTWVYDKGEWY
                     YVSSSGSMIANDWVKDNGK"
     gene            58003..58302
                     /locus_tag="VQ865_000280"
     CDS             58003..58302
                     /locus_tag="VQ865_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001013971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4651 domain-containing protein"
                     /protein_id="HET3134704.1"
                     /translation="MNGMKAKKMWMAGLALLGIGSLALATKKVADDRKLMKTQEELTE
                     IVRDHFSDMGEIATLYVQVYESSLESLVGGVIFEDGRHYTFVYENEDLVYEEEVL"
     gene            58299..58616
                     /locus_tag="VQ865_000281"
     CDS             58299..58616
                     /locus_tag="VQ865_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000615765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HET3134705.1"
                     /translation="MIQPASLEELASLVEKAGKKVFLFVADWCGDCRYIYPALPEIEE
                     TNPEFTFIRMDRDQYMDLAKLWDVYGIPSLVVLEKDKEIGRFVNRDRKSKEQINDFLA
                     GLK"
     gene            58632..59258
                     /locus_tag="VQ865_000282"
     CDS             58632..59258
                     /locus_tag="VQ865_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 and tRNA-binding domain-containing
                     protein"
                     /protein_id="HET3134706.1"
                     /translation="MIFTYNKEHVSDVLMVIVKNSGDAKLNVERKGKVARVFLKENGE
                     TVAWNIFEVSSLFEIAERGQVFLSDEQVARLNQELQAEGFTEEIVNDKEPKFVVGEIV
                     EMVAHPDSDHLNICQVAVASDKIVQIVAGAPNARVGLKTIVALPGAMMPKGNFIFPGE
                     LRGEKSFGMMCSPRELHLPNAPQKRGVLELSEDQVVGTPFDPAKHWTA"
     gene            59291..60052
                     /locus_tag="VQ865_000283"
     CDS             59291..60052
                     /locus_tag="VQ865_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3134707.1"
                     /translation="MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKS
                     EFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYE
                     ELDMLTMLDTNVKGLMAVTRCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAA
                     VKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDI
                     ADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK"
     gene            60130..60525
                     /locus_tag="VQ865_000284"
     CDS             60130..60525
                     /locus_tag="VQ865_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HET3134708.1"
                     /translation="MYNKVIMIGRLTSTPELHKTNNDKSVARATIAVNRRYKDQNGER
                     EADFVNMVLWGRLAETLASYATKGSLISVDGELRTRRFEKNGQMNYVTEVLVTGFQLL
                     ESRAQRAMRENNAGQDLADLVLEEEELPF"
     gene            60795..61079
                     /gene="groES"
                     /locus_tag="VQ865_000285"
     CDS             60795..61079
                     /gene="groES"
                     /locus_tag="VQ865_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HET3134709.1"
                     /translation="MLKPLGDRVVLKIEEKEQTVGGFVLAGSAQEKTKTAQVVATGQG
                     VRTLNGDLVAPSVKTGDRVLVEAHAGLDVKDGDEKYIIVGEANILAIIEE"
     gene            61095..62717
                     /gene="groL"
                     /locus_tag="VQ865_000286"
     CDS             61095..62717
                     /gene="groL"
                     /locus_tag="VQ865_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166362.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HET3134710.1"
                     /translation="MSKEIKFSSDARSAMVRGVDILADTVKVTLGPKGRNVVLEKSFG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     IKNVTAGANPIGIRRGIETAVAAAVEALKNNAIPVANKEAIAQVAAVSSRSEKVGEYI
                     SEAMEKVGKDGVITIEESRGMETELEVVEGMQFDRGYLSQYMVTDSEKMVADLENPYI
                     LITDKKISNIQEILPLLESILQSNRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITEDLGLELKDATIEALGQAARVTVDKDSTVIVEGA
                     GNPEAISHRVAVIKSQIETTTSEFDREKLQERLAKLSGGVAVIKVGAATETELKEMKL
                     RIEDALNATRAAVEEGIVAGGGTALANVIPAVATLELTGDEVTGRNIVLRALEEPVRQ
                     IAHNAGFEGSIVIDRLKNAELGIGFNAATGEWVNMIDQGIIDPVKVSRSALQNAASVA
                     SLILTTEAVVANKPEPVAPAPAMDPSMMGGMM"
     gene            62855..63610
                     /locus_tag="VQ865_000287"
                     /pseudo
     CDS             62855..63610
                     /locus_tag="VQ865_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567550.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
     gene            complement(64051..64584)
                     /locus_tag="VQ865_000288"
     CDS             complement(64051..64584)
                     /locus_tag="VQ865_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HET3134711.1"
                     /translation="MKLPKEGDFITIQSYKHDGSLHRTWRDTMVLKTTENAIIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGTSYYCNMASPYYLDEEALKYI
                     DYDLDVKIFTDGEKRLLDVEEYERHKRKMNYSDDLDYILKEHVKILVDWINNGRGPFS
                     EAYVNIWYKRYVELKNR"
     gene            complement(64673..65449)
                     /gene="recX"
                     /locus_tag="VQ865_000289"
     CDS             complement(64673..65449)
                     /gene="recX"
                     /locus_tag="VQ865_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000705102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HET3134712.1"
                     /translation="MKITKLEKKKRLYLMELDGQQTSYITEDTIVRFMLSRDKVISKE
                     ELTEIQDFAQFSYGKNLALYHLSFKARTEKEVREYLKKYDIDKNIVSQVIANLKEDKW
                     INDGQYAYAIINTNQLSGDKGPYVLTQKLAQKGISKSTIEENLKEFDFSEVAQRVANK
                     LLKKYEGKLPSRALQDKIIQNLTNKGFSYSDAKIAFDDLDSQVDQETTQELIFKELDK
                     QYSKYARKYEGYELKQRLTQVLARKGYDFSDIASALREYL"
     gene            complement(65459..66235)
                     /locus_tag="VQ865_000290"
     CDS             complement(65459..66235)
                     /locus_tag="VQ865_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001086342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside 3'-phosphotransferase"
                     /protein_id="HET3134713.1"
                     /translation="MNSKTPRFSILDFPEQLRSYIKGANLSDSSSHSSATVLYIDSGY
                     YLKIDQKGRLAQETKIASWFETEGLGTPVITYLSANKDFLLTKEAIGSNALAFLNQPE
                     RLCQTLAQALNKLHSLKPQSFPSENHLKRYKEKALKNYQKGTFYNKTLLPQFHIHSRE
                     EAYQLIQEKGYILKADAFIHGDACLPNFILKDASHFSCFIDLGLAGFSDRHIDLFWAI
                     WSLHYNLQDATYAELFLDYYGREYVNMDKLRLVAAFEAFR"
     gene            66292..67647
                     /gene="rlmD"
                     /locus_tag="VQ865_000291"
     CDS             66292..67647
                     /gene="rlmD"
                     /locus_tag="VQ865_000291"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3134714.1"
                     /translation="MNLKVKQKIPLKIKRMGINGEGIGFYQKTLVFVPGALKGEDIYC
                     QITSIRRNFVEAKLLKVNKKSKFRIVPSCTIYNECGGCQIMHLHYDKQLEFKTDLLHQ
                     ALKKFAPAGYENYEIRLTIGMQEPKYYRAKLQFQTRKFKNQVKAGLYAQNSHYLVELK
                     DCLVQDKETQVIANRLAELLTYHQIPITDERKVLGVRTIMVRRARKTGQVQIIIVTNR
                     QLNLTQLVKELVKDFPEVVTVAVNTNTAKTSEIYGEKTEIIWGQESIQEGVLNYEFSL
                     SPRAFYQLNPEQTEVLYSEAVKALDVDKENHLIDAYCGVGTIGFAFAKKVKTLRGMDI
                     IPEAIEDAKRNAKRMGFDNTHYEAGTAEEIIPRWYKEGYRADALIVDPPRTGLDDKLL
                     DTILTYVPEKMVYISCNVSTLARDLVRLVEVYDLHYIQSVDMFPHTARTEAVVKLIKK
                     V"
BASE COUNT        20331 a        12402 c        14989 g        19931 t
ORIGIN      
        1 aacgtatgtt tcgagagaag cgctaaggcc acttttaaag atttccaaga ctatctttct
       61 tcatgaggaa agatagtttt ttggtatgat tttcaccccc aaaatacaag gggaatgtgt
      121 tacaatagta gtaacagata atagaaaaga gaatagatga gaattgcaga ttatagcgtg
      181 accaaggcag tgctggagcg tcacggtttt acctttaaaa agtcctttgg gcaaaatttc
      241 ttgacggata ccaatatcct acaaaaaatc gtggatacgg ctgagattga tgaccaggtc
      301 aatgtcattg aaatcgggcc aggtattggt gccttgaccg agtttttggc tgagcgtgca
      361 gcagaagtta tggcctttga gatcgaccat cgtttggtac cgattttggc agataccttg
      421 cgtgattttg acaatgtgac tgtagtcaac gaggacattc tcaaggtcga tttggcgcaa
      481 catatccaga atttcaaaaa tcctgacctg ccaatcaagg tagtggctaa tttgccttac
      541 tacatcacaa cgcctattct catgcactta atcgagagtg gcattccttt tagtgagttt
      601 gtggtcatga tgcaaaaaga agtggcggac cgtatctcgg ctcaaccaaa taccaaggct
      661 tacggtagct tgtctatcgc tgtgcagtat tacatgacag ccaaggttgc ctttatcgtg
      721 ccgcgtacag tctttgtgcc agcaccaaat gtagactcag ccatcttgaa aatggtgcgc
      781 cgtccagtgc cagctgtagc agtggaagac gagaactttt tctttaaggt ttccaaggct
      841 agttttaccc atcgccgcaa gaccttgtgg aataacttga caggttactt tggcaagact
      901 gaagaggtca aggacaagct gaccaaggct ttggaccaag caggcttgtc accaagtgtg
      961 cgtggggaag ctctcagctt ggaagagttt gccagcctag cagatgcact taaagggcaa
     1021 ggactctaag atgcagggac aaaaacttaa ttttggtaaa aaatgaagta gatctttcta
     1081 tgataaaacg catattatca aggttttcca acacctgata atatgcgttt ctctgatttt
     1141 aaagactttt gtcccagcat tttggtatat atagtagatt gaaataagat atgaacaaag
     1201 agattaggaa agtcaaatta atttctagaa acgttttaga atccttagtg tactatttct
     1261 aggttcaatc cactatagtt cgtattaaat caatgaatca gtagttgatt gggcacttca
     1321 ttagattttt aaactcgtga aatacctgat tagccttgtg gggctggacc aacgaaatcg
     1381 agtctttgtc taccgatttc tgctccatcg atttttcact cgacatttat atatgaaatt
     1441 taccctaaca atactattct atcataaaac tagtagaaaa aacagtcttg tatttattta
     1501 tttttgtgat atattagtag gtgaataagg gcatgttcaa tagacttaga aaggagtttt
     1561 ttgtagcaaa ctattgaaat atatgtagcc aagatttgga acagttacct ataggagtgt
     1621 gaattgcttt cagatagata tcctattctg aaatataagg aaacgttcat cttatattag
     1681 ctatttttac tcctcttgaa aatgggaagg atatattcat gagaaaaaaa ttagtcaata
     1741 gccttatgtg tgcagtggtt ctatcaggat ttcctattgc gacttatgca aatgagaaga
     1801 atattggtcc aaatataacg gtttctaatg ggcaaactag attatctata cctgaaaaaa
     1861 atggggtaga agtgattcag tctgaagaaa atcgagttgt atatgaggtg aaagaggcag
     1921 ctaaaataga aactagcgat ggagatatgg tggcccccat tgttgtggat agccgtatta
     1981 cttctataaa caatcaagta gtacaaggaa aaactgttta taccgctgat ttagagaagg
     2041 ctacttttgt tgaagagggt tacaataagc ttgctaaacc aacgaatata ttagaccata
     2101 tttttggtat acagaaagtg cacgcttata ctcaaaacat tactactcat caaagtcagt
     2161 ttgatagtac ttatagtgtg gaattgtata ctgttgttca ctgggtgagt tatgatggag
     2221 gtgtacaaaa aaatattact aaaataagtg gaggagttga cttccatgaa agggatatcg
     2281 aaatagaatc ttcaagtgtg gaagttagac aaggtggttg gtattcatcc cagcaaaaat
     2341 ggtttcatcc aggtgcaaga agtagttggg agtatagcac aggtttttct aaggttggac
     2401 caggtgaaaa tcgggtagta actaattata ctgttaattt gattcgatat ggagatagat
     2461 ggtcagctta cttgcaaaat aatccatggt agagaatatg aaaaaaataa ttagtcccct
     2521 tcttttttta gtgagctatt gtttaccttt ctataaagta gttgatgtga ttgatggaga
     2581 aacgactgaa agtatgattt atggttttca atttatgttg cgaaattggt caatctatct
     2641 actttgtctg ttcttattga tgatttttct atggcgaaag caaggatggg ttctaattgt
     2701 agcagtattt atgtatgttc tttgtttact atctctaacg acctatgatt tctatcaatt
     2761 tccaatcatc tatctaccag gctattttat agagtctgtc tttccccaca tgatgtatgg
     2821 agtttatatt catatttttt gtcttgcttt attaggtttt ttctattaca cacagaaaaa
     2881 gtaaagcgaa cagggagttt taggctctct gttcgcctgt ttttatataa ggaggtagat
     2941 tcgttatttt tgtataaaac ttggtatcta aagcgtgagt gtatcttttt cttttagaat
     3001 agacttatcg aaattgtaaa gagaagctaa gctaaaatag cttttttttg ttataatgga
     3061 actaacaatt ttaaaggagt tattttgcag ggacaaatca ttaaagcctt ggctgggttc
     3121 tactatgtag agagtgatgg ccaagtctat caaacacgcg cgcgtgggaa tttccgtaaa
     3181 aaagggcata ccccttacgt tggggactgg gtagatttct ctgccgagga aaattcagaa
     3241 ggctatattc tcaagattca cgaacggaaa aacagtctgg tccgtccgcc tattgtcaat
     3301 atcgaccaag ctgtagtaat catgtctgtc aaggaacctg attttaacag caatttgctg
     3361 gatcgtttct tggttctttt ggagcataag ggtattcatc ccatcgtcta tatttctaaa
     3421 atggatttgt tggaagacgg gggagaactg gatttttacc agcagaccta tggtgacatc
     3481 ggatatgact ttgtgaccag taaagaggaa ctcctgcctt tgttaacagg caaggttacg
     3541 gtctttatgg ggcagacggg tgttgggaaa tcaactcttc tcaataaaat cgcaccagat
     3601 cttaatcttg aaacgggaga aatttcagac agtctgggtc gcgggcgtca taccactcga
     3661 gctgttagtt tttacaacct caatgggggt aaaatcgcag acacaccagg cttttcatca
     3721 ctggattatg aagtatcaac ggctgaagac ctcaatcagg cctttccaga gattgccact
     3781 gtcagtcgag actgcaaatt ccgtacttgt acccataccc atgagccgtc ctgtgctgtc
     3841 aagccagcag ttgaagaagg taccattgca cccttccgtt ttgacaacta cctgcaattc
     3901 ctcagcgaaa ttgaaaatcg cagagaaacc tataaaaaag tcagcaaaaa aattccaaaa
     3961 taaggagaaa cctatgtctc aatacaagat tgctccgtca attctggcag cagattatgc
     4021 caactttgaa cgtgaaatta aacgcctaga agcaactggg gcagagtatg cccatatcga
     4081 tattatggat ggtcattttg tgccgcaaat cagttttggt gcgggtgtgg tcgaagctct
     4141 tcgtcctcat agtaagatgg ttttcgactg ccacttgatg gtgtcaaacc ctgagcatca
     4201 tttagaggac tttgtgcgtg caggtgcgga tattattagt atccatgtgg aagcaacgcc
     4261 tcatattcat ggtgccctcc aaaagattcg ttcactcggt gtcaagccat cagttgttat
     4321 caatcctggt acaccagttg aagcgattaa gcatgtgctt catctagttg accaagtcct
     4381 agtcatgaca gttaaccctg gatttggtgg tcaagccttt ctgccagaaa ccatggataa
     4441 ggttcgtgag ctggttgccc ttcgtgatga aaaaggtttg aactttgaga ttgaagtgga
     4501 tggtgggatt gatgaccaaa ctattgctca atccaaagaa gctggtgcga ccgtttttgt
     4561 agcaggttcc tatgtcttta agggagatgt caatgagcga gtacaaactc tcagaaaaca
     4621 actggactag ggttgccgtt tttgcaggcg gagaccgcgg tcattatcgg acggactttg
     4681 atggttttgt tggtgtggat cgaggctcgc tctggatctt ggaagaagat ttgcctcttg
     4741 ctctagcagt cggagatttt gattctgtga cggaagaaga gcgacaggtg attcaaaaac
     4801 gtgcccagta ttttgtccaa gcccggccag aaaaagatga tactgatttg gaattggctc
     4861 tcttgaccat ctttaagcaa aatcctcagg ctcaggttac tattttcggt gccttgggtg
     4921 gccgtattga ccatatgttg gccaatgtct ttctgcctag caatcctaag ttggcaccct
     4981 atatgcatca aatagaaatt gaggatgggc aaaacttgat tacttattgt ccagaaggaa
     5041 tcagtcagct agaacctcgt tcagactacg actatctagc ctttatgcca gttcgggata
     5101 gccagctgac tattcttgga gccaagtatg agttgacaga ggaaaatttt ttctttaaaa
     5161 aagtgtacgc ttctaacgaa tatatagata gggaagtgtc ggtaacttgc ccagatggtt
     5221 atgtggtcgt actgcatagc aaggacagga ggtaggatgg aaagtttact tattctatta
     5281 ttaattgcca atctagctgg tctctttctg atttggcaaa ggcaggatag gcaggagaaa
     5341 cacttaagta agagcttgga ggatcaggca gatcatttgt cagaccagtt ggattaccgc
     5401 tttgaccaag ccagacaagc cagccagtta gaccaaaaag atttggaagt ggttgtcagc
     5461 gaccgtttgc aagaagtgcg gattgaattg caccaaggtc tgacccaagt ccgtcaagaa
     5521 atgacagata atctcctcca aactagagac aagacagacc aacgtctcca agccttgcag
     5581 gaatcaaatg agcaacgttt ggaacaaatg cgccagacgg tcgaggaaaa actagaaaag
     5641 accttgcaga cacgcttaca ggcttccttt gagacagttt ctaaacaact ggagtctgtc
     5701 aatcgtggcc ttggagaaat gcagacagtt gcccgtgatg tcggagctct taacaaggtt
     5761 ctctctggaa ccaagacgcg agggattctg ggagaattgc aactggggca aattattgaa
     5821 gacatcatga cacctgccca gtacgaacga gaatacgcaa cggttgaaaa ctctagtgaa
     5881 cgagtggagt atgccatcaa gttacccgga caaggcgacc aagaatacgt ctatctgcca
     5941 attgactcta agtttccact ggcagattat taccgcttgg aagaagccta tgagacaggt
     6001 gacaaggatg agattgaacg ctgtcgtaag tcactcctag caagcgtcaa gcgctttgct
     6061 agggatatta ggaacaagta catagcacca cctcggacaa ccaactttgg aatcttgttt
     6121 gttccgacag aaggtcttta ttcagagatt gtgcgcaatc cggtcttctt tgatgatttg
     6181 agacgggaag aacagattat tgttgcagga ccaagtaccc tatcagccct tcttaactct
     6241 ctatcagttg gtttcaagac ccttaatatc caaaagagtg ccgaccatat cagcaagact
     6301 cttgccagtg tcaagaccga gtttggcaag tttggtggta ttctggtcaa ggcacaaaaa
     6361 catctccaac atgcctctgg caatattgat gaattattaa accgtcgtac catagctatc
     6421 gagcggacgc tccgtcacat tgagttgtca gaaggtgagc ctgcgcttga tctactccat
     6481 tttcaagaaa atgaggaaga atatgaagat tagtcacatg aaaaaagatg agctatttga
     6541 aggcttttac ctaatcaaat cagctgacct gaggcaaact cgagctggga aaaactacct
     6601 agcctttacc ttccaagatg atagtggcga gattgatggg aagctctggg atgcccaacc
     6661 tcataacatt gaggccttta ccgcaggtaa ggttgtccac atgaaaggac gccgagaagt
     6721 ttataacaat acccctcaag tcaatcaaat tactctccgc ctgcctcaag ctggtgaacc
     6781 caatgaccca gccgatttca aggtcaagtc accagttgat gtcaaggaaa ttcgtgacta
     6841 catgtcgcaa atgattttca aaattgaaaa tcctgtctgg caacggattg tccgaaatct
     6901 ctacaccaag tatgataagg aattctactc ctatccagct gccaagacca accaccatgc
     6961 ctttgaaacg gggttggctt atcatacggc gaccatggta cgtttggcag acgctattag
     7021 cgaagtttat cctcagctca ataagagcct gctctatgcg gggattatgc tgcatgactt
     7081 agctaaggtt atcgagttga cggggccaga ccagacagag tacacagtgc gaggtaatct
     7141 tcttggacat atcgctctca ttgatagcga aattaccaag acagttatgg aactcggcat
     7201 cgatgatacc aaggaagaag tcgttttgct tcgtcatgtc atcctcagtc accacggctt
     7261 gcttgaatat ggaagtccag tccgtccacg tattatggag gcagagatta tccatatgat
     7321 tgacaatctg gatgcaagca tgatgatgat gtcaacagct ctggctttgg tggataaagg
     7381 agagatgacc aataaaatct tcgctatgga taatcgttcc ttctataaac cagatttaga
     7441 ttgataattt aagaaaaatg agcatttttt aggataagaa tgttcgtttt tttatgtgaa
     7501 tatggtataa taagtaaaag acaaaaatga atactcttcg aaaatctctt caaactaggg
     7561 tagtatcgcc ttgtcgtatg tatatatgca ggtatattac agggtttgtc agttctattg
     7621 acaatctcaa aacagtgttt tgaaccacca gcgaccagct ttctagtttg ctttttgatt
     7681 ttttgaataa aaatggaata ggaaatagaa atgaaattaa gaagaagtga tcggatggtt
     7741 gtcatttcca actatttgat taataatcct tataaactaa ctagtctcaa tacttttgct
     7801 gaaaagtatg agtctgctaa atcatccatc tcagaagata tcgtcattat caaacgcgcc
     7861 tttgaggaaa ttgaaatcgg tcatatccag acagtgactg gggctggcgg aggtgtcatc
     7921 ttcacaccgt ctatttcgag tcaggatgct aaggaaatgg ttgaagactt gcgtaccaag
     7981 ttgtcagaaa gtgaccgtat cttgccaggt ggttatatct atctgtctga tttgcttagc
     8041 acaccagcca tcttgaaaaa tattggtcgt attattgcca aaagctttat ggaccaaaaa
     8101 attgacgcgg ttatgaccgt agcaactaag ggtgtgccac ttgcaaatgc agttgccaat
     8161 gtcctcaatg tctcttttgt cattgtgcgc cgtgacctga aaattaccga aggttcaact
     8221 gttagcgtca actatgtttc aggttcaagt ggtgaccgta tcgagaaaat gttcctttca
     8281 aaacgtagtc ttaaggcagg cagccgtgtc ttgattgtgg atgacttctt gaaaggtggc
     8341 ggaacggtca atggtatgat tagtctcttg cgcgagttcg actcagaact ggcaggtgta
     8401 gcggtctttg cggacaatgc ccaagaagaa cgtgaaaagc agtttgacta caagtcactc
     8461 ttgaaggtaa ccaatattga tgtcaagaac caagccatcg atgttgaggt tggcaatatc
     8521 tttgacgaag ataaataaga gatagaacta aaggttggaa cgattgtccc agcctttctt
     8581 tgcaaacaga atagaaggaa gcttatgaaa acaccattta tcaatagaga agagttagaa
     8641 gcgattgttg ccgagttccc gactcccttt cacttgtatg atgagaaggg gattcgtgag
     8701 aaggcaagag ccgtcaacca agctttttcg tggaacaagg gctttaagga atattttgca
     8761 gttaaggcta ctccaactcc agctattttg aaaattctcc aagaagaagg ttgtggtgtg
     8821 gactgctcta gttatgtaga gcttttgatg agccataaac tggactttct gggttctgag
     8881 attatgttct cttccaacaa cacgccagac aaggaatacg cctatgcacg tgaattgggt
     8941 gcgaccatta acttggatgc ctttgaagat attgaacatc tggagagagt agcaggcatt
     9001 ccagaaatca tctcttgtcg ttataatcct ggaggcgttt ttgaactggg gacagacatt
     9061 atggacaatc ctggggaggc taagtttggc atgaccaagg accagctctt tgaagccttt
     9121 gctatcttga aggaaaaagg agccaagact tttgggattc actccttcct agcgtccaat
     9181 accgtgaccc atctctatta tccagagttg gctcgtcagc tctttgaact ggctgttgaa
     9241 atcaaggaaa agttgggcat ttcgctagac tttatcaatc tttctggcgg tattggtgtt
     9301 aattatcgtc cagaccagga gccgaacgat atcgccttga ttggtgaggg agttcgtaag
     9361 gtgtatgaag aagttcttac gtcagcaggt cttggtcagg tcaagatttt caccgaattg
     9421 ggtcgtttta tgctggcacc tcacggtgct ctagtcacaa gagtgactca taagaaggaa
     9481 acctaccgta cctatctagg tgtggatgcc tcagcagtca acctcatgcg tccagctatg
     9541 tacggagctt accatcatat tagcaacgtg acccatccag atggaccagc tgaagcggta
     9601 gatgtggttg gttcactctg tgaaaacaat gataaatttg cagtcaatcg cgaactgcct
     9661 catacagaaa tcggtgattt gctggtaatt catgatacag gtgcccacgg attttcaatg
     9721 ggctaccagt ataatgccaa attacgttct gcggaaatcc tctataccga agaaggtaaa
     9781 gcccgtcaaa tccgccgtgc agagcgccct gaggactatt ttgcaacctt atatggcttc
     9841 gattttgaag aataatctga taatagattg aaaatgaaat tgaaaaacag attgctttct
     9901 aaaaaatagg caaaaatctt gtttttcctt caagtcgtga tataataaaa ctataaaacg
     9961 ttttcaagga aggtaacgat atgtctgaag aaacaattga ttatggacaa gtgacaggaa
    10021 tggtgcattc gacagaaagc tttgggtcag tagatgggcc tggtattcgc tttattgtct
    10081 ttttgcaggg ctgtcacatg cgttgccagt attgccacaa cccagacact tgggctatgg
    10141 agtccaataa gtcacgtgaa cggacggtag atgatgtctt gacagaggcc ttgcgctacc
    10201 gtggtttctg gggaaataag ggtgggatta cagtcagtgg aggagaagct ctcttgcaga
    10261 ttgatttcct gattgctctc ttcaccaagg ctaaggaaca aggaatccac tgtaccttgg
    10321 atacctgtgc tcttcctttc cgtaataaac cacgttacct tgagaagttt gacaaactca
    10381 tggctgtcac tgacttggtt cttttggata tcaaggaaat caacgaagaa cagcacaaga
    10441 ttgtcactag ccaaactaat aaaaatatct tggcttgtgc ccagtatcta tcagatattg
    10501 gaaaacctgt ctggattcgc cacgtgctag ttccaggatt gacagacaga gatgatgact
    10561 tgattgaact tggtaagttc gtcaagaccc tcaaaaatgt tgataagttt gaaattctac
    10621 cttatcacac catgggtgag ttcaagtggc gtgaacttgg aattccatat tccctcgaag
    10681 gagtcaaacc accaacagca gatcgcgtca agaacgctaa aaaactcatg gataccgaaa
    10741 gttatcaaga ttatatgaaa cgtgtacatg gatagaaaag aagcctgatg gaaacatcgg
    10801 gcttttgatt tgcaaaaaga cttagcaaat cagctaagcc tttttcttct tatctcgaac
    10861 gttgttttcc agcgttgcga tttttgtgtt ttttcttgct tgtgatagca gttggttgtt
    10921 caggggtaac gtcttttcgt ccacttggtt tagagaaagc acttgctttt ggtgggttct
    10981 tggctagttc ttcacggact tttttgcgaa gttttggacg aacgatatag ttgacgataa
    11041 actgttggag aatcatcatg aaaccaccga caacccagta aagtgtgaca ctagctggtg
    11101 agaagaggga gaagacgacg atcatgagtg ggctcatgta aatcattttc ttgatttgtt
    11161 ctctttgcat ttcatcttct actccgtgaa gtgaaaggag cgattgaaga tagtaaagga
    11221 caccagcaca ggcaaccaaa atcatacttg gagaacctag aggaatgcct aggtagcttg
    11281 cttgagcaac cccttcagta tgttgggcag caaagtagat agcagagaag aaaggcattt
    11341 gaaggaggat agggaaacat cctacaccac caaacatgct gatgccgtgc tctttttgag
    11401 cggcaaagag ggcttgttgg gcttcgagtt tttcttcttg agtagttgct tctttgagac
    11461 gtgtttggtg tggctcaagg acatgcttga gagcgttcat cttttcagag tgaagcgttg
    11521 ccttccatga ttggtagata ccaagtggta agataatcaa gcgtacgata atggttacga
    11581 taatgatagc gacaccaaag cctagacctt tatcagtagc gaagtacttg atggcttcag
    11641 ccataggcgc tccgatcgta ttccaaataa atcctgttgg ctgacctgtg gttttatcga
    11701 cattgacaca gccagtcaag acaagcaaca tagccactcc catagccgag aatgcaaaac
    11761 gtttaataga tttcactgtt tttattcctt ctttaaaaat tatacctttc tattctactg
    11821 tttttttaca aaatatacaa tagttctgga gacctaattt gcgattttaa agtcagagta
    11881 gggaggaaag ttgcttagtt tgacatctaa gtagcttact tttgaaaaag gtgtcggtcc
    11941 ttttcggatt tcttggataa attttgccat gatagcagat gagtctgctt gggctaagat
    12001 ttccactgtg ccatcgtcgt tattccatac tcgacctgtg atgccaccaa tttcaagtgc
    12061 caagctgtaa acaccccaac gaaagccgac tccctgtacc ctaccttggg caatcattct
    12121 aaccttttgc ataccaaccc cctttgattg tgttataata tttctatgac tattataacc
    12181 tcaaaagcca attctgtggt aaaaaatgcc aagaaattac gccaaaaaaa ataccgcaag
    12241 tctgcctatt tgattgaagg ctggcacttg tttgaagaag ctgtccaagc tggagtgacg
    12301 attgagaaaa tctttgccct agaaaattat cgagatcagt tagctacttt ttcgcaaact
    12361 gtctgggtgt cagaggatat tttgctagat ttggcggatt ctcagactcc acagggaatt
    12421 gtggcggtgg ttcaaaaaga agaagtagga caagctgatt tgagtcaggg caagttcttg
    12481 tttttggaag atgtgcaaga tcccggtaat gtaggaacta tcattcgaac tgcggatgca
    12541 gcaggtttta caggagtgat tgtttcagat aagtcggcag acatctacag tctcaaaacc
    12601 ctacgttcca tgcaaggtag tcatttccat ctgcccattt accggatgac tagtccagcg
    12661 cttcttgacg aaactaaaaa ggtagctatc ccagtgctag caacaaccct atctaaagat
    12721 tctgttgatt acagagaact gccttctata gaaaattttg tactagttat gggaaatgag
    12781 ggtcaaggaa ttagtcccct tatggctgaa agtgcagacc agttggtcca tattagcatg
    12841 aaggggcagg ccgagagttt gaatgttgca gttgcagccg gtattttaat cttccattta
    12901 agctaatttt aacttttttt gttataatca aggaaagatg ttcacagaaa aggagaaaag
    12961 gatgaatcac actattatac atgaccgtgc aggtctcaat caattttacg ctaaggttta
    13021 tgcctttgtt ggtctgggaa tcggactatc tgctttggta tcaggcctta tgttgacggt
    13081 ctttcagtct cagttggttt acttgttgat gcaggggcgt ctctggttga ccattgctac
    13141 ttttgcggag ttggctttgg ttttcgttgc cagtagcatg gcttcaagaa atagtccagc
    13201 tgctcttcca gtatttttac tttactccgt tttaaacggc tttaccctta gttttgtggt
    13261 ggctttctat actccgggta cagttttatc tgcctttgta tcgagcgccc ttctcttctt
    13321 tgtcatggcg gcagttggta tctttaccaa gaaagacttg agtgggattg gtcgagcaat
    13381 gatggcagct ctcattggtt tactgattgc tatggtagtc aatattttct tggctagtgg
    13441 cttctttgat tatatgatta gcgtagccat ggttttggtt ttttcagggt tgattgcttg
    13501 ggataaccaa aagattcgcc tcgcctatga acaatcacaa ggtcgtgtag cgacaggctg
    13561 ggtggtgtca atggctctca gcatctatct tgattttatc aatcttttcc taagtattct
    13621 acgtatcttt ggtcgcaatg actaaaaggt ctatgaaatc agtgttttga gtgacactga
    13681 tttttttaaa ttttctcttt tcttttcttg gaaataggtg tataatacgt ttattaaatt
    13741 tttgaggagt tgtctatgaa gaaaagtttt atccatcaac aagaagaaat ttcctttgtc
    13801 aaaaacactt ttacccagta tttgaaagat aagctagaag ttgtcgaagt tcaaggtcct
    13861 atcttgagta aggtcggtga cggaatgcag gacaacctgt ctggtgtgga aaatccagta
    13921 tcggtcaagg ttctccaaat ccctgatgct acttatgaag tggtgcactc acttgctaaa
    13981 tggaaacgcc acaccttggc tcgttttggc tttggtgaag gagagggtct ctttgtccac
    14041 atgaaagccc ttcgtccaga tgaggattcc ttggatgcaa cccactctgt ttatgttgac
    14101 cagtgggact gggagaaggt tatcccaaat ggtaagcgta acatcgttta tctaaaagaa
    14161 acagttgaga agatttataa ggctattcgc ctgactgagc tagctgttga agctcgctat
    14221 gacatcgagt ctatcttgcc aaagcaaatc acctttatcc atacagaaga attggtagaa
    14281 cgctacccag acttgacacc gaaagaacgt gaaaatgcga tttgtaaaga atttggagcc
    14341 gtctttttga ttggtatcgg tggcgagttg ccagatggta aaccgcacga tggacgtgca
    14401 ccagactatg atgactggac aagcgagtct gagaatggct acaagggtct aaatggtgat
    14461 attcttgtct ggaatgagtc tttaggtgga gcctttgagt tgtcttctat gggaattcgt
    14521 gtagatgaag aaactcttag acgtcaggtg gaaattacag gtgatgaaga ccgcttggaa
    14581 ttggaatggc acaagtcttt gttgaatggc ctattcccat tgacaatcgg tggaggaatt
    14641 ggacaatctc gtatggccat gttcctactt cgcaagagac acatcggaga agtgcaaaca
    14701 agtgtttggc ctcaagaagt ccgcgatact tacgaaaata ttttgtagag aatcgaaccg
    14761 caaggttcgg ttttctttct ctttttgtct ataatttggt ataataaaca gtatgaaaat
    14821 cgtatcagga atctatgggg gacgtcccct caagacacta gaaggcaaga caacaagacc
    14881 tacttcggat aaggttaggg gagccatttt taacatgatt ggtccctact ttgaaggggg
    14941 acgagtcttg gacctttatg caggtagtgg tggtttatct atcgaagcag tatcgcgtgg
    15001 catgtccagt gctgttttgg tggagcgaga ccgtaaggct cagaccatcg tggctgaaaa
    15061 tatccagatg accaaggaag ttggaaaatt tcaactcctc aagatggatg cagagagggc
    15121 attggaacag gtatctgggg aatttgacct cgttttctta gaccctccct atgccaagga
    15181 acaaatcgta gcagatattg aaaaaatggc taagagagag cttttttctg aagatgttat
    15241 ggttgtgtgc gagacggata aggccgttga acttccagaa gagattgcct gtctgggtat
    15301 ctggaaggaa aagatttatg gaattagtaa ggtgacagtc tatgtcagat aagattggct
    15361 tattcacagg ctcatttgat ccgatgacaa atgggcatct ggatatcatt gaacgggcga
    15421 gcagactttt tgataagctt tatgtgggta ttttttttaa tccccacaaa caaggatttc
    15481 tccctcttga aaatcgtaaa cgggggctag aaaaggcttt gggacatttg gaaaatgttg
    15541 aagtcgtggc ttctcatgat gaattggtgg tcgatgttgc aaaaagactg ggggctactt
    15601 tcctagtacg ggggttgagg aatgcggcgg atttgcaata tgaagctagt tttgattact
    15661 acaatcatca gctgtcttct gatatagaga ctatttattt acatagccgg cctgaacatc
    15721 tctatatcag ttcatcaggt gttcgagagc ttttgaagtt tggtcaggat attgcctgcc
    15781 atgttcccga gagtattttg gaggaaataa gaaatgaaaa aaaaagatta gatggccctt
    15841 atacgtcatt gcggccttga ttgtgacttt cttggcattt gtagtgccct tgccttatta
    15901 tatagaggtt ccaggtggtt cggaagatat tcgccaagtc cttaaagtaa atgacacaga
    15961 agataaggaa gctggtgcct atcaattcgt tacggttggt gttcaacatg ccactttagc
    16021 tcatatgatt tatgcttggt tgacaccttt tacagatatt cgtagtgctc aggagactac
    16081 aggtggttct tccgatgttg aatttatgcg aatcaatcaa ttctacatgc aaacatcgca
    16141 aaatatggcc aagtatcaag gactaaaaac agctggtaag gatatcgaac tcaagtactt
    16201 tggagtttat gttttgaatg tgacggataa ttcaaccttt aaagggattc tcaatatctc
    16261 tgatacagtc acagcagtca atgatcagac ctttgatagt tccaaagact tgattgatta
    16321 cgtcagttct caaaaattag gggattccgt caaggtcacc tatgaagagg atgggcaaac
    16381 caagtctgca gaaggaaaga ttatcacctt ggaaaatggc aaaaatggaa ttggaatcgg
    16441 cttgattgac cgtacagagg taatcagcaa tgtcccaatt agcttttcaa cagctggtat
    16501 tggcggccca agtgctggtc tcatgtttag tctagctatc tatactcaaa tagctcaccc
    16561 agatcttcgt aatggtcgta ttgttgccgg tacaggtacc attgaccgcg atggtaatgt
    16621 gggagacatt ggaggtattg ataagaaggt tgtagcttcg gctagggcag gtgctgctat
    16681 tttctttgct cctgataacc ctgttagcga agaagaacaa aaggcgcatc tggacgcgaa
    16741 aaacaactac caaacagccc tagaagcggc taaaacaatc aagacggata tgaaaatcgt
    16801 gcccgttaaa accctacaag atgcgattga ttacttgaaa aacaatccct aatttttgag
    16861 tgaagtttcc aaactagcgc acaaacagag aagatggtat aatagtcaaa tggttcaatt
    16921 attattcact ctaagtagtc atatgctctt tatttatgtg agtttttacc ttttaaagga
    16981 tcttgttaga tgggagaagg ttttaaaagt gacagatgat aatacaagaa aagttcgttt
    17041 attagtagcc ttttttagca ttgtcatagg ctacatcctg agttctttct ttattagcct
    17101 gtatcatttg tggcaagaag cgcttagagg attattataa aatcaagagt aaaggaaacg
    17161 agtatggata aaattgtggt tcaaggtggc gataatcgtc tggtaggaag cgtgacgatc
    17221 gagggagcaa aaaatgcagt cttacccttg ttggcagcga ctattctagc aagtgaagga
    17281 aagaccgtct tgcagaatgt tccgattttg tcggatgtct ttattatgaa tcaggtagtt
    17341 ggtggtttga atgccaaggt tgactttgat gaggaagctc atcttgtcaa ggtggatgct
    17401 actggcgaca tcactgagga agccccttac aagtatgtca gcaagatgcg cgcctccatc
    17461 gttgtattag ggccaatcct tgcccgtgtg ggtcatgcca aggtatccat gccaggtggt
    17521 tgtacgattg gtagccgtcc tattgatctt catttgaaag gtctggaagc tatgggggtt
    17581 aagattagtc agacagctgg ttacatcgaa gccaaggcag aacgcttgca tggcgctcat
    17641 atctatatgg actttccaag tgttggtgca acgcagaact tgatgatggc agcgactctg
    17701 gctgatgggg tgacagtgat tgagaatgct gcgcgtgagc ctgagattgt tgacttagcc
    17761 attctcctta atgaaatggg agccaaggtc aaaggtgctg gtacagagac tataaccatt
    17821 actggtgttg agaaacttca tggtacgact cacaatgtag tccaagaccg tatcgaagca
    17881 ggaaccttta tggtagctgc tgccatgact ggtggtgatg tcttgattcg agacgctgtc
    17941 tgggagcaca accgtccctt gattgccaag ttacttgaaa tgggtgttga agtaattgaa
    18001 gaagacgaag gaattcgtgt tcgttctcaa ctagaaaatc taaaagctgt tcatgtgaaa
    18061 accttgcccc acccaggatt tccaacagat atgcaggctc aatttacagc cttgatgaca
    18121 gttgcaaaag gcgaatcaac catggtggag acagttttcg aaaatcgttt ccaacaccta
    18181 gaagagatgc gccgcatggg cttgcattct gagattatcc gtgatacagc tcgtattgtt
    18241 ggtggacagc ctttgcaggg agcagaagtt ctttcaactg accttcgtgc cagtgcagcc
    18301 ttgattttga caggtttggt agcacaggga gaaactgtgg tcggtaaatt ggttcacttg
    18361 gatagaggtt actacggttt ccatgagaag ttggcgcagc taggtgctaa gattcagcgg
    18421 attgaggcaa gcgatgaaga tgaataagaa atcaagctac gtaatcaatc gtttactttt
    18481 agtcatcata gtactgattt taggtactct ggctctagga atcggtctaa tggtaggtta
    18541 tggaatcttg ggcaagggtc aagatccatg ggctatcctg tctccagcaa aatggcagga
    18601 attgattcat aaatttacag gaaattaggc tggagaacca gcctttttct aaagataagg
    18661 agaaatatga acaaaaaaac aagacagaca ctaatcggac tgctagtgtt attgcttttg
    18721 tctacaggga gctattatat caagcagatg cagtcggcac ctaatagtcc caaaaccaat
    18781 cttagtcaga aaaaacaagc gtctgaagct cctagtcaag cattggcaga gagtgtctta
    18841 acagacgcag tcaagagtca aataaagggg agtctggagt ggaatggctc aggtgctttt
    18901 atcgtcaatg gtaataaaac aaatctagat gccaaggttt caagtaagcc ctacgctgac
    18961 aataaaacaa agacagtggg caaggaaact gttccaaccg tagctaatgc cctcttgtct
    19021 aaggccactc gtcagtacaa gaatcgtaaa gaaactggga atggttcaac ttcttggact
    19081 cctccaggtt ggcatcaggt caagaatcta aagggctctt atacccatgc agtcgataga
    19141 ggtcatttgt taggctatgc cttaatcggt ggtttggatg gttttgatgc ctcaacaagc
    19201 aatcctaaaa acattgctgt tcagacagcc tgggcaaatc aggcacaagc cgagtattcg
    19261 actggtcaaa actactatga aagcaaggtg cgtaaagcct tggaccaaaa caagcgtgtc
    19321 cgttaccgtg taacccttta ctacgcttca aacgaggatt tagttccctc agcttcacag
    19381 attgaagcca agtcttcgga tggagaattg gaattcaatg ttctagttcc caatgttcaa
    19441 aagggacttc aactggatta ccgaactgga gaagtaactg taactcagta aaagataagc
    19501 ctaaactcct atgtcactta tggatgtagg agttcttttt actagtttaa gcagggctag
    19561 aataggtact aagaaaaaat agtaacttct aaaactaact tccagtttcc cacaacctag
    19621 cttttagtat gagaaaaacg cgtgaaatca gtggaaatcc gtcttagact aacttccagt
    19681 tttgggagag agatggaagt tacgctaaga aaaaaataat atgtattgga ttaaattttg
    19741 tgatataata aaggataaga tactatttta ggagaagaac tatggaagac ccaagtagtc
    19801 agaatttgtt gctacaattt gttttattgt ttatcttgac ggtattaaat gcctttttct
    19861 cagccacaga aatggccatg gtttctctta atcgtgcccg agttgaacaa aaggcggaag
    19921 aaggagacag acgctacatc cgcctgctga aggtactaga aaatcctaac cactttttat
    19981 caaccattca ggtaggaatc accctgatta caatcttatc aggggcgagt ttaactgata
    20041 ctctaggacg tgtgattgcc tcttggcttg ggaatggcga aacagcacaa gccgtggcaa
    20101 cttttctatc cttggcattt ttgacctata tttccatcgt ttttggggaa ttatatccta
    20161 agagaatcgc tcttaatcta aaggatgcct tggcaattcg tacagcgccg attatcattg
    20221 ggatcggaaa actagtcagt ccttttgttt ggcttttagc tgcttcgacc aatttcttga
    20281 gccatttgac tcctatgtca ttcgatgatg cggatgaaaa gatgacccgt gatgaaattg
    20341 cctatatgct gacaaatagt gaagaaacat tggatgctga tgagattgag atgctacaag
    20401 gtgtcttttc gctcgatgaa ctgatggcac gagaggttat ggtgcctcga acggatgcct
    20461 ttatggtgga tattcaggat gatagtcaag ccattatcca aagtatttta aaacaaaatt
    20521 attctcgtat cccggtttat gatggggata aggacaatgt aattggaatc attcacacca
    20581 agagtctcct taaggcaggc tttgtggacg gttttgacaa tattgtttgg aagagaattt
    20641 tacaagatcc actttttgta cctgaaacta tttttgtgga tgacttgcta aaagaactgc
    20701 gaaataccca aagacaaatg gcaatcttgc tggatgaata cggtggtatg gctggtttgg
    20761 tgactttgga agacctctta gaggaaattg ttggtgaaat tgatgatgaa acggacaaag
    20821 cagcaataga tgttcatcag attggcgagg atacctacat tgttcaagga actatgaccc
    20881 tcaatgattt caataattac tttgatgttg aactggaaag tgatgacgtt gataccatcg
    20941 ctggttatta tttgacagga gtgggaacca ttccaacgac tgagaaactc agctatgaat
    21001 tggtcagcca aaacaaacag tttatcttaa ccaatgataa agtgaagaat ggacgtgtta
    21061 ccaaggtaaa agtccaaatc acagaagtcg aaatagaaga agaaacagaa taaactagag
    21121 gcttttgtca ccaggcgtga cgaagctttt ttcaattgat ttcaaaaggg aattatgcca
    21181 tggaaagaac tctgccacaa actcgctcca aaagttttta aagttatacg tatttattcg
    21241 agggaaaata aaaaaagccc ttcaaattgg gctttctgtt catttgaaac ctgataaatc
    21301 aagttataga aggcggtaga cggatttgaa ccgacgatca agcttttgca gagccgtgcc
    21361 ttaccacttg gctataccgc cttaacgttt attattatac cttgaaaatg attttcagtc
    21421 aatagttttt tcagtttttt gtaccatagc gtgattcgaa tgtgatgcca agttttctat
    21481 gggaaaaaaa ttaccaaaaa cctactgaat ccccttgaaa aatctagcta aatagggtat
    21541 aatatgggta atcatttgtc gtaggttttg tctgaaatat tgtccagaca aggctcacag
    21601 cagttaaatc ttctgaaaaa gtcagattta gctgctcttt ttgtgctttt tttcaagatt
    21661 ttgagcattt gtaacagagg cttaaagatt ctgaaaattc gtcaagagga cacggtgata
    21721 aggggtttac aaccatatgg cgattagaaa agcctgattg acaaggcttg gaacttattt
    21781 acaaaggaga atcatcttgg caggacatga cgttcaatac gggaaacatc gtacccgtcg
    21841 tagtttttca agaatcaaag aagttcttga cttaccaaat ttgattgaaa ttcaaactga
    21901 ctcattcaaa gctttcctag accacggtct taaggaagtg tttgaagatg tattgccaat
    21961 ttcaaacttc acagacacaa tggagttgga atttgttgga tatgaaatca aggaaccaaa
    22021 atacacgcta gaagaagctc gtattcacga tgctagctac tcagcaccaa tttttgtaac
    22081 cttccgcttg atcaataaag aaacaggcga aatcaagacc caagaagttt tctttggtga
    22141 tttcccaatc atgacagaaa tgggtacttt catcatcaat ggtggtgaac gtattatcgt
    22201 ttctcagttg gtccgctcac caggtgttta ctttaacgac aaagtagaca aaaatggtaa
    22261 ggtgggctat ggttcaactg ttatccctaa ccgtggagct tggttggaac ttgaaagcga
    22321 ctcaaaagat atcacctaca ctcgtatcga ccgtactcgt aagattccat ttacaacctt
    22381 ggttcgtgct cttggtttct caggtgatga tgaaatcttt gatatttttg gtgacagcga
    22441 attggttcgc aacactgttg aaaaagatat ccacaagaat ccaatggact ctcgtacaga
    22501 cgaagccttg aaagaaattt acgaacgcct tcgtccaggt gagcctaaga cggctgaaag
    22561 ctcacgtagc ttgcttgtgg ctcgcttctt tgacccacgt cgctatgact tggcagcagt
    22621 tggtcgttac aaaatcaata aaaaactcaa tgttaaaaca cgtttgctca accaaaccat
    22681 tgcagagcca ttggtagacc ctgaaactgg agaaatcttg gtagaagctg gtacgattat
    22741 gactcgtagc gtgattgaaa gcattgaaag ccatttggat ggcgacttga acaagattgt
    22801 ctacatccca aacgatgcag ccgttgtgac tgagcctgtt gttcttcaaa aattcaaggt
    22861 tgttgctcca actgatccag atcgcgtcgt aacgatcatt ggtaatgcta acccagatga
    22921 caaggttcgt acggtgactc ctgcagatat ccttgctgag atgagctact tcctcaactt
    22981 ggctgaagga cttggccgtg tagatgatat cgaccacctt ggaaatcgtc gtatccgtgc
    23041 ggttggtgaa ttgcttgcca accaagtacg tttgggactt tctcgtatgg aacgtaatgt
    23101 ccgtgaacgt atgtctgttc aggacaatga agtcttgaca ccacaacaaa ttatcaatat
    23161 ccgtcctgta acagctgcag ttaaagaatt ctttggttca tcacagttgt cacagttcat
    23221 ggaccaacac aacccgcttt ctgagttgtc tcacaaacgc cgtttgtcag ccttaggacc
    23281 tggtggtttg actcgtgacc gtgccggata tgaagtacgt gacgtgcact acactcacta
    23341 tggtcgtatg tgtccaatcg agacacctga aggacctaac atcggtttga tcaataactt
    23401 gtcatcttac ggacacttga acaaatatgg ttttgttcaa acaccatacc gtaaggttga
    23461 ccgtgaaaca ggtgttgtca cgaacgaaat tgtttggttg acagctgatg aagaagatga
    23521 atatactgta gctcaggcta actctcgtct gaatgaagat ggaacctttg ctgagaagat
    23581 tgtcatggga cgtcaccaag gggtcaacca agagtatcca gctaatattg ttgactacat
    23641 ggacgtttca ccaaaacagg tagttgccgt tgcgacagca tgtattcctt tcttggaaaa
    23701 cgatgactcc aaccgtgccc tcatgggagc caatatgcaa cgtcaggctg tgccattgat
    23761 taatcctcag gcaccttacg ttggtactgg tatggaatac caagcagccc acgattctgg
    23821 tgcggctgtg attgctcagt atgatggtaa agttacttac gcagatgctg acaaggtaga
    23881 agttcgtcgt gaagatggtt cattggatgt ttaccacatc caaaaattcc gtcgttcaaa
    23941 ctcaggtact gcttacaacc aacgcactct cgtaaaagtt ggtgatgtcg ttgaaaaagg
    24001 cgatttcatc gctgacggac cttctatgga aaatggagaa atggcgcttg gacaaaaccc
    24061 aatcgttgcc tacatgactt gggaaggtta caacttcgag gatgccgtta tcatgagcga
    24121 acgcttggtg aaggacgatg tctacacatc tgttcacctt gaagaatacg aatcagaaac
    24181 gcgcgataca aagcttgggc ctgaagaaat cactcgcgaa attccaaacg ttggtgaaga
    24241 tgccctcaaa gaccttgacg aaatggggat tatccgtatt ggtgctgagg ttaaagaagg
    24301 tgatattctt gtaggtaaag taacacctaa gggtgagaaa gatctttcag ctgaagaacg
    24361 tctcttgcac gctatctttg gagacaagtc tcgtgaagtg cgtgatactt ctcttcgtgt
    24421 accacacggt gccgatggtg tcgttcgtga tgttaagatc tttacacgtg taaatggaga
    24481 tgagttgcaa tcaggtgtta acatgttggt tcgtgtttac atcgctcaaa aacgtaagat
    24541 taaggtcgga gataaaatgg ccggacgtca cggaaacaaa ggggttgtct ctcgtatcgt
    24601 tcctgtagaa gacatgcctt accttccaga cggaactcca gtcgacatca tgttgaaccc
    24661 acttggggta ccatcacgta tgaatatcgg tcaggttatg gagcttcacc ttggtatggc
    24721 agctcgtact cttggtattc acatcgcgac accagtcttt gatggagcaa gttctgaaga
    24781 tctttggtca actgttaaag aagcaggtat ggatagcgat gccaaaacga tcctttacga
    24841 tggacgtact ggtgaaccgt ttgataaccg tgtttctgtc ggagtcatgt acatgatcaa
    24901 actccaccac atggttgatg ataaattgca cgcgcgttca gtcggaccat actcaactgt
    24961 tacccaacaa ccactcggag gtaaggctca gtttggtgga caacgtttcg gtgagatgga
    25021 ggtttgggct cttgaagcct acggtgcgtc aaatgtcctt caagaaatct tgacttacaa
    25081 gtcggacgat atcaacggac gtttgaaagc ctatgaagct attacaaaag gcaaaccaat
    25141 tccaaaacca ggtgttccag aatccttccg agttcttgtc aaagaattgc aatctcttgg
    25201 tcttgacatg cgtgtcctag acgaagatga ccaagaagtg gaacttcgcg acttggatga
    25261 aggaatggac gaagatgtca tccacgtaga tgaccttgaa aaagcccgcg aaaaagcagc
    25321 ccaagaggct aaagcagcct ttgaagctga agaagctgag aaagcaacaa aagcggaagc
    25381 aacagaagaa gctgctgaac aagaataagc agttcactta gaatagaaag ggaagaaata
    25441 gtggttgatg taaatcgttt taaaagtatg caaatcaccc tagcttctcc aagtaaagtc
    25501 cgttcatggt cttatggaga agtcaaaaaa cctgaaacaa tcaattatcg taccttgaaa
    25561 ccagaacgtg aaggactctt tgatgaagtg atctttggtc ctacaaaaga ctgggaatgt
    25621 gcttgtggta agtacaaacg cattcgttac agaggaattg tttgtgaccg ctgtggggtt
    25681 gaagtaacgc gtacgaaagt tcgtcgtgag cgtatgggac atatcgaatt gaaagctcct
    25741 gtatctcaca tctggtactt caaggggatt ccaagccgta tgggcttgac ccttgatatg
    25801 agccctcgtg ccctcgagga agttatctac tttgcggctt atgtggtgat tgatcctaag
    25861 gatacaccac ttgagcacaa gtctatcatg acagagcgcg aataccgaga gcgcttgcgc
    25921 gaatatggtt atggttcatt tgttgccaag atgggtgcgg aagccatcca agaccttttg
    25981 aagcaagtag atcttgaaaa agaaattgct gaactcaaag aagaattgaa aacagctact
    26041 ggacaaaaac gtgtcaaagc catccgtcgt ttggatgttt tggatgcctt ttacaagtct
    26101 ggaaacaaac ctgaatggat gattcttaac atccttccgg ttatcccacc agatcttcgt
    26161 ccaatgttgc agttggatgg tggccgtttt gcctcatctg acttgaatga cctttaccgc
    26221 cgtgttatca accgtaacaa ccgtttggct cgtttgcttg agttaaatgc accaggtatc
    26281 atcgttcaaa atgagaaacg tatgcttcaa gaagcagttg acgctttgat tgacaatggt
    26341 cgtcgtggtc gtccaatcac aggaccaggt agccgtccat tgaaatcatt gagccacatg
    26401 cttaaaggta aacaaggacg cttccgtcaa aacttgctcg gtaaacgtgt tgacttctca
    26461 ggacgttccg ttatcgccgt tggtccaact cttaagatgt accaatgtgg tgtgccacgt
    26521 gaaatggcga ttgaactctt taaaccattt gtcatgcgtg aaatcgttgc ccgtgatatc
    26581 gtgcaaaacg tcaaagcagc taaacgcttg gtggaacgcg gagatgagcg tatctgggat
    26641 atccttgaag aagtgattaa agaacaccca gtgcttttga accgcgcacc gacccttcac
    26701 cgtttgggta tccaagcctt cgagccagtc ttaattgatg gtaaggctct tcgcttgcac
    26761 ccacttgtct gtgaagccta caatgccgac tttgacgggg accaaatggc catccacgta
    26821 ccactttcag aagaagcaca agcagaagct cgtatcctca tgctagctgc tgagcacatc
    26881 ttgaacccga aagatgggaa accggtagtt actccatctc aggacatggt tttgggtaac
    26941 tactacttga ccatggaaga agctggtcgc gaaggtgaag gaatggtctt caaagaccgt
    27001 gacgaagcgg ttatggctta ccgcaatggt tatgttcacc tccactcacg tgttggtatc
    27061 gcaacagaca gcctcaacaa gccttggaca gaagagcaaa gacataaggt cttgcttaca
    27121 acagttggta aaattctctt caacgatatc atgccagagg ggctaccata cttgcaagaa
    27181 ccaaacaatg ccaacttgac agaaggtgtt ccagctaaat acttcttgcc acttggtgga
    27241 gatatcaagg aagctatcag caatcttgag ctcaaccctc cattcaagaa gaaaaacctt
    27301 ggaaatatca tcgctgaaat cttcaaacgt ttccgtacga cagaaacttc tgccctactt
    27361 gaccgcatga agaacctcgg ttaccaccac tcaactcttg caggattgac agtgggtatt
    27421 gccgatatcc cagtcgttga tgacaagact gaaatcattg aagaatcaca caaacgtgtc
    27481 gaacaaatca ccaaacaatt ccgtcgtggt atgatcacag acgacgagcg ttacaatgct
    27541 gttacagctg aatggcgtgc tgcccgtgaa aaacttgaga aacgcttgat tgctaaccaa
    27601 gatcctaaga acccaatcgt tatgatgatg gactctggag cccgtggtaa catctcaaac
    27661 ttctcacagc ttgccggtat gcgtggtctg atggctgctc cgaatggacg tatcatggaa
    27721 ttgccaatcc tttcaaactt ccgcgaaggt ttgtcggtat tggaaatgtt cttctcaact
    27781 cacggtgctc gtaaaggtat gaccgatacg gcccttaaga cagccgactc aggttacttg
    27841 actcgtcgtt tggtcgacgt tgcccaagac gttatcatcc gtgaggacga ctgtggaact
    27901 gaccgtggtc tcttgatccg ttctatcgca gaaggaaaag agatgatcga gtctctcgaa
    27961 gagcgtctca acggtcgtta cactaagaaa actgttaaac atccagaaac tggtgcagtg
    28021 attattggtc caaatgaatt gattacagaa gacaaggcgc gtgaaattgt caatgctggt
    28081 gtggaagaag tgactatccg ttctgtattt acatgtaaca ctcgtcacgg tgtctgccgt
    28141 cactgttacg gtatcaactt ggcgactggt gatgcggttg aagttggtga agcagttggt
    28201 accattgctg cccaatctat cggggaacct ggtacacagc ttacaatgcg taccttccac
    28261 acaggtgggg ttgcctcaaa taccgatatc actcagggtc ttcctcgtgt ccaagaaatc
    28321 tttgaagccc gcaatcctaa aggggaagcg gttatcacag aggttaaagg acaagttact
    28381 gctatcgaag aagatgcatc aactcgtacc aagaaagtct ttgttaaggg tgaaactggc
    28441 gaaggtgaat atgtcgttcc atttacagct cgtatgcgtg tcgaagttgg gggccaagta
    28501 gcgcgtggtg ctgctctgac agaaggttct atccaaccaa aacgtctcct tgcagttcgt
    28561 gatgtcttgt cagttgaaac gtaccttctc ggtgaagtac aaaaagttta ccgtagccaa
    28621 ggggtagaaa tcggtgacaa acacatcgag gtaatggttc gtcaaatgat ccgtaaagtc
    28681 cgtgtcatgg atccaggtga tacagatctt ctcatgggta ccctcatgga tatcaatgac
    28741 tttacagatg ccaacaaaga tgtccttatc gcaggtggag ttccagcgac aggtcgccca
    28801 gtccttatgg gaattaccaa agcctcactt gaaacaaaca gtttcttgtc agcggcttcc
    28861 ttccaggaaa caactcgtgt ccttactgac gcagctatcc gtggtaagaa agaccatctc
    28921 cttggactta aagaaaatgt tatcatcggt aagatcatcc cagctggtac tggtatggcc
    28981 cgttaccgta accttgaacc atatgctgtc aacgaagaag aataccttaa tcctccagta
    29041 gaggaagaag gaaatgaaga aacaacagaa gtagttgtgg atactgccgt tgaaactgtg
    29101 gaagaaacag tagaataata gagaatgaga gaaccctcgg gttctctcat tctctattct
    29161 gaaaactttc tccatttttc cacgaaatgt ggtaaaataa aagaaagaag ctgacaaagg
    29221 agacgggtat ggaacaaaca ttctttatca tcaaaccaga tggtgtaaaa agagggctag
    29281 tgggtgaagt gttaaagcgc atcgaacaac gtggatttac aatcgaaaaa ttggagtttc
    29341 gttcacaagt ttcagaagag ttgattgacc agcactatca ggacttggtt ggtcagagtt
    29401 tttacccacc gattcgtgaa ttcatgactt caggtccagt tcttgtgggt gtcatttctg
    29461 gtcccaaagt aatcgaaact tggcggacca tgatgggtgc aactcgtcca gaagaagctt
    29521 taccaggcac tattcgaggt gattttgcaa aagctgctgg agaaaatgag gttatccaaa
    29581 atgttgtaca tggttcagat tcagaagagt cagctaagcg agaaattgct ctttggtttt
    29641 aagagtggat tggctcaatc aattggttaa aagctcattt gaatagaaag tatagtcaat
    29701 tagtttaaga catgacgcat gatatcaaac tttttagttt ttgatatggt gcgttttttg
    29761 attaagtgac tattagttcg tctcgctccg ttaggtgcga gacaaaaaaa cacccgctat
    29821 gcgggtgcgc gtcgaaggtt ataccaaaaa aactccaaac gcgatacaat aaaggtgttc
    29881 aagccaattg taaagcgaaa ggagaaaaat atggcacaaa aggttctttt gtcctgttct
    29941 tgtttcaatt gactatattt ctatactttt tcttcctttc tctgtgaaaa tcgcaagttt
    30001 ttcccacctt ttctcaatac tgaaacaaca tctttccaga acttcaataa tttctttttg
    30061 tgttaaatca ttatttaact aaatctttgg aggcaatacg ttttcaaagc gactttttta
    30121 ccataggttt tgagccttca acacagatta ctaagccaaa aatgctctaa atttttgaaa
    30181 ttctaacaaa ttccactcaa ctttatcatc atctttgact ttcacaatat cttcctcaaa
    30241 ataacatgga ataaagatag ttttcttttg aaacggttgt aggaggaaaa tctctcctac
    30301 actattattg attctgagag gaaattgcaa aatatcatct accaaatttt caattattaa
    30361 gattttttgc agtttatctg aattagaatc gcaaggcttc tcaacaatat aattgtcgaa
    30421 ttttttcatt ctaacttcct ctccactatt tcttccttta tcaagaaaaa gttacctcaa
    30481 tattaataaa gtacaattct aaattaactc caattattga ttcatgataa tatttcagta
    30541 actcatcgtg caattaaaaa caaggatttt tatttcagac gatccatcgt gaacacttca
    30601 tcagccatct cccaaattgc tggattatgt gttgcgataa tgattagcct attatcatct
    30661 cgaagagata gcaaaatctc cataatcaac tgagaagttg ctgggtctat tgaagctgtt
    30721 ggctcatctg ccagaataaa gggtggattc tttaagataa cttttgccaa ggcaacccgt
    30781 tgcgattctc cgcccgataa ctcaaagatg cgcttatcta ggtcaagata agtcaggccg
    30841 acctgttcta aagcctgctt ctgcctcaac cgctgttccg accgactcaa cttttgacca
    30901 atgagaccta gcttaaggtt ttcttcaata ctttggtttt caattaagcc aaagttctgg
    30961 aagaggtagc ccaattcgtg acggaaaaaa tcactcgatt tataattggc caagtcttta
    31021 cctcggtaaa aaatcgtccc atcataaggt tctaatttcc caatcatgtt catcaaggtt
    31081 gtttttccgc taccacttga accaattaag gcatagactt ttccagcctc aaatgtcatt
    31141 gaaagattcg aaaataactc tcgttctcca aaagatttac tcacctgttt aagttcaatc
    31201 atattaacct cccttcaaaa caagcatgga catcttgttt tctttctgca tttggacatg
    31261 taactgtaaa agagatagac cagtaaagag taacaagact aagaaagcaa ctcctatctc
    31321 tacctgaaga aatacactcg caacaaatcc cagtaaaaac acacccagtt gagcaaagag
    31381 ataagtgcga tggatttcta agaacctgag acctgcaatg cgtttgataa aaatggcacg
    31441 tctaaattct tcaaagtaga gcctattcat agtgttaaac aacaagattg aagttgcaat
    31501 cccaagccca gctcctgcta gcattaccca acgttccctc tgaatattat ccaataatgt
    31561 gatgtagttg tggtaacctg tttgcatttc tgagacccaa ttttcaatgc cttgtctctg
    31621 gataagctcc tgggcatcag acaattgatt aaagagaacg tagttctgta ctgcgtctat
    31681 ccaaaacaaa atggactgtg gaccagttga ttggggtgtt ataacaatga tgattggatc
    31741 tttcaaaaac tgctggtaag aaataggggt cgtattatac acaaaacgat cctgacctga
    31801 ttctaaataa cctaccgtag cagtcatttg ctgtcgttca tcttgactag acatgcgact
    31861 ggttaagtcg tcttcaaaaa cagatttata atgttcttcc tctgaacgga ggtgttcagg
    31921 cagcaataag acaaactccc ctacataaag gtgattcatc ttttgctcaa tagttgtatc
    31981 tacaggaatg ttttgacgct ccaagtattg cggtgtgacg ataaggacat tgccattcgg
    32041 gttgtaatcg tgccattctg tagaggttat caagtttttg gaggaagcca tgccattttg
    32101 caaagtacgg tcaattaact ggtgtctaga taagaaagcc ttttgttctg aaacagccag
    32161 atccatcaat tgataccaag ttctgagttt cctttgagct tgttcatcaa aaccaggact
    32221 cgttccttca cggctgattg atagggtaat cagttgcctt tcctgactcc aagcctcttg
    32281 tccaatccga tgctgttgcc aggcttggga atactttaag ctactcccta ttcccagcgt
    32341 tacaataata atcgctaata gttgaccgat taaaatcaaa ctaatgattc ctctgacagg
    32401 cacttgccct tttataatct gcatcaggtg tatctttttt atcccaactg cgaagagttg
    32461 agcgaaaaac agggagatcg acaacaagat gagattataa ctgagcaagc ctgctcctat
    32521 ggtcattagg gattgcgttg gaagcgacag aattttttgc ataagaatgg cgagcacgcc
    32581 agctaaactg aaaccaacag ctatcccttt caaatcctca ccaactggtc taaggaaaat
    32641 ggaccaccgt ttctctcctg aaatgaggcg aatgcccgac gaccgtaatt ggctaatttg
    32701 actaattaaa gtcagtgcta caaaggttaa gatgaaaatc aatagactga ttaactgaaa
    32761 tccgttacta aagatagcca ttaacgtaga tagtttagat ggaattgtca ggttcatgtt
    32821 agtcaagcca agttgactta gctcctccct tagcaagtga atatctaggt gtccatcgaa
    32881 tacaaaatag tttgtttcaa cactactact ttgagcatct tctagttttt tttcctgaag
    32941 cccatcaggc aactttccgt ccccaaaggt cgtataagaa aaaactgtag taccttctga
    33001 gttagaatct tggtgttgaa tcgcaataaa gctatctgtt tcttctgcta gtttttccaa
    33061 gcgtgtagca acatgctgaa aagttgtttc aggggaagaa tcatgtacaa caacgttagg
    33121 gtaataatag gagacatatg tatcagtcca aatggtaaat acccaaacaa agaacaaact
    33181 agcaagcagg ttggatatga gtataaataa ttttttcata gtgcattcct tattctaaaa
    33241 cagagggcag aaatacccct gccctctata aactaacaag cttactaata tctatctggt
    33301 attgttacaa gctctcatca gaataccttt ctctaaatag ttgaatttta aagtaatacg
    33361 aaatcaatca gccttcccaa catcaagacc attggacttc ttttgtgatt ggactcgaat
    33421 ctccaattgt ctattcttct gaataaactg ttggtaagga attgtgttac taagcataaa
    33481 aacacctagt aatactaata tagctaattt ttgaattcca cgatttttct tcattcgtga
    33541 aacccttttc tttttccttg tttttatttt aatatatata tattattcgg tcaagcattt
    33601 ttatgtaatt tttgactttt tttagtttat taccataaag aattatttat tcttttaact
    33661 tgctattttg aactaaaaat tttataatgc aattaagcaa ataggaaggt ttattatctt
    33721 taatgaatac actcgcagag aaattcagat tgaaaagaaa agagttgaga ctctcccaac
    33781 aaactcttgc agaaggaatt tgtgaacaaa gtcagattag taaaattgag agagggcatt
    33841 tcattccctc cgcagacctt ttgttcaaac tctctcaacg acttgaagta ccattagatt
    33901 atttttttaa tgaacaaatt gaaattaaat ctaacctctc taatttcaag caattgtctg
    33961 ctcgactatt agacgataga aattatgacg atttggaata tatttataga atagagattg
    34021 aacgaagtac ttttctaaca ctagaagacc gaacttacct tgaatggatt aaagctatta
    34081 ttgacttcta tcaatatgac agtaagtgtg aggcaatttc ttcattggaa aatatattat
    34141 taaaagtctc ttcaaatact ctgatttatt taaaggcgtt gaatactcta tctaatttct
    34201 attccttagt gggtcgtgaa caagaatatg aggcaaacta ctctcattta atagagttgt
    34261 atcagacaaa aaatttggac catcaagagt ttttatttgg ctacatcaga gttcgttaca
    34321 actacgctca ctacctagta tcaaaggaaa aatataatga agccatccaa gaagctcttg
    34381 aaacgattga actctgtaaa caaagacaga caagctacca attggctcct ctacttattc
    34441 ttgtaggaaa tgctggagcc aaatttctag acagagaaca agtcaaaaat tattatatag
    34501 aagcaagaga gttatgtaag atttataaca atcctttaat gttgatgaag atagaaaatt
    34561 atttgaagga actagatact gtttagttaa tcttgacatt atagtttttc tgaaacgtta
    34621 aataacctgt aaggctgata gttagattaa tactatcagc cttataatta tgtgactctg
    34681 agtccgtctc gctccgtgag gtgcgagaca aaacaaccac ccgtttgacg gattttcatg
    34741 atttcaaatt tatattcttc gtaaatctct tcaaaccacg tcagctctat ctgcaatctc
    34801 aaaacagtgt tttgagcaac ctgtggctag ctacctagtt tgctctttga ttttcattga
    34861 gtattagtct ctagtgtttg tttagcgtct taaagagaca tttgagaaga ttagaaacag
    34921 ttctctcttt tctcctagta taatgattgg taggaaggga gagagaagat gaaatcaatg
    34981 agaatcttat ttttgttagc tttaattcaa atcagtttga gtagctgttt cctatggaag
    35041 gaatgcatct tgtcctttaa acaaagtaca gcttttttca tcggaagcat ggttttcgtt
    35101 tcaggaatct gtgctggagt aaattatctt tatactcgta agcaagaagt ccatagtgtc
    35161 ctagccagta agaagtcggt gaagcttttt tacagtatgt tactcttaat taatttgtta
    35221 ggagctgttc ttgttttgtc agataacttg ttcatcaaaa atacgctgca gcaagaatta
    35281 gttgactttt tattgccatc cttctttttc ctatttgggc tagatttgct gattttttta
    35341 cccttgaaaa aatacgtgcg cgattttctt gctatgctgg acagaaaaaa gacagtgttg
    35401 gtgactattt tagcaacact tcttttctta agaaatccaa tgaccattgt ctcacttctg
    35461 atttatattg gactgggctt gttttttgca gcctatcttg tcccaaattc ggttaagaag
    35521 gaagtttcct tttatggtca tattttccga gatcttgtat tggtcattgt tacgctcatt
    35581 ttcttttaga gaaagcctgt tttttatgga tgttatgatg ataagtttag taggaaaata
    35641 gacacaaaag aaaagttttt ggtataataa gagtatgtac ataaaaaatg aagaagagtt
    35701 gcaagcctta ggggagcgtt tgggccatct attagcaaag aatgatgttt taatcttaat
    35761 tggagaactg ggtgcaggta aaacgacctt tactaaagga cttgcaaaag gattacagat
    35821 ttctcaaatg attaaaagtc ctacctatac tatcgtgaga gagtatgaag gtcgacttcc
    35881 actttatcac ctagatgttt atcgtattga aggagatgct gattctatcg acttggatga
    35941 gtttatcttt ggtggcggcg tgactgttat tgagtgggga aatctcttag gagatgcctt
    36001 gccagatgct tatttagaat tggaaattct aaaagaagca gatggacgcc gtttaaattt
    36061 tcaggcaaag ggtttgcgtg ctgagaaatt gtcagaggag cttcaatatg gagtatgaat
    36121 tgctcattag ggaagcagag cccaaagatg cagctgaatt agtggccttt ttaaatcgtg
    36181 tgagtttgga gacagacttt accagcctag acggagatgg tattctcttg actagtgagg
    36241 agatggaaat attcctcaac aagcaagcta gttcggacaa tcagataacc ttacttgcat
    36301 tcttaaatgg caaaattact ggtattgtaa atattacagc tgatcagcgt aagagagtcc
    36361 gtcatattgg agatctcttc attgtgattg gaaaaagata ttggaataat ggcttgggaa
    36421 gtttgttgct agaagaagcg atagagtggg cacaagcaag tggcattctg cgtcgtctcc
    36481 aactgactgt ccaaactcgt aatcaagcag cagtccatct ttatcaaaag catggctttg
    36541 tcattgaagg tagccaagag cgtggggcat atatagaaga agggaaattt atcgatgttt
    36601 acttgatggg taaactgata ggttagtaga aatatggtta aaaaaattat tggaatggtg
    36661 ctagctttac tttctgtaac tgtagtagga gtaggtgttt ttgcttatac tatttatcaa
    36721 caagggacag aaaccttagc taaaacctat aaaaaaatcg gcgaagaaac caaggttatt
    36781 gaagcgactg aacctctaac cattctgtta atgggagtgg acaccggaaa tgttgaacga
    36841 actgaaactt gggtcggtag aagtgatagc atgatcttga tgacagtgaa tcctaaaacg
    36901 aaaaaaacaa caatgatgag tttagagcgg gatattctga cgcgcattga atcagggaat
    36961 ggtcaggctc atgaagcgaa actgaactca gcatatgcag atggtggagc agagcttgct
    37021 atagaaacca ttcaaaaaat gatgaatatc catattgatc gctatgtgat ggtcaatatg
    37081 agagggttgc aaaaattagt ggatgcagta ggaggtatta cagtcaataa tatcctaggt
    37141 ttcccaattt ctatcagtga ccaagaagaa tttaatacca tttctatcgg tgttggggag
    37201 caacatattg ggggagaaga agccctagtc tatgcacgaa tgcgttacca agatcctgag
    37261 ggggattatg gtcgtcaaaa acgtcaacgt gaagttattc aaaaagtcat ggaaaaagct
    37321 ctcagtttaa atagcattgg tcattatcaa gagattctaa aagctttgag tgacaatatg
    37381 cagaccaata ttgatttgtc tgcaaaaagt atccctaact tgctaggcta taaagattca
    37441 tttaaaacca ttgaaactca gcagttgcag ggtgaaggag agatacttca aggtgtttct
    37501 taccagattg tttcgagagc acatatgttg gaaatgcaaa atatactccg acgttctttg
    37561 ggacaagaag aagttactca gcttgaaacc aatgcggttt tatttgaaga tttatttggc
    37621 agagcacctg ttggtgatga agataattaa cttttgatac aaataaaaaa atcaatcgta
    37681 ggaaaattcc tgcgattttt tcaaaaaaat acgaatagat aggtaggagg aaacatgaaa
    37741 gcagaaatca ttgctgttgg aacagagatt ttgacaggac agattgtcaa caccaatgcc
    37801 cagtttttgt cggaaaaact agctgagatt ggggtagatg tatattttca gacggctgta
    37861 ggagacaatg aagttcgtct cttgtctttg cttgagattg ccagtcaacg tagcagtctg
    37921 gtgattttga caggcggttt ggggccaact gaggacgacc taaccaaaca aaccctagct
    37981 aaatttttag ggaaagcatt agtctttgat cctcaggctc aggagaagtt ggatatcttt
    38041 tttgccctgc gaccagacta tgcccgaaca ccgaataacg aaagacaagc tcaaattgta
    38101 gaaggagcga ttccactgcc aaacgaaaca ggactggctg ttggaggaaa attagaagta
    38161 gacggagtga cctatgtcgt ccttccaggt ccgccaagtg aattgaaacc catggtctta
    38221 aaccaacttc tacccaagtt gatgacaggg agcaagctgt attcccgagt tcttcgtttc
    38281 tttgggattg gcgagagcca gctggttacg attttggctg atttaattga taatcagatc
    38341 gatcctacct tggcccctta tgccaagaca ggagaagtca ctctacgtct gtcaacaaag
    38401 gctagcagtc aagaagaggc gaatcaagcg ctggatatct tggaaaatca aatcttggac
    38461 tgccagactt tcgaaggaat ttctttacga gacttttgct atggttatgg ggaagaaact
    38521 agtttagcca gcattgtggt agaagaactg aaaaggcaag ggaaaaccat cgcggctgca
    38581 gagagtttga cggcaggtct tttccaagct accgtggcga atttttctgg agtttcaagt
    38641 atatttaagg gtggttttgt gacctatagc ttggaggaaa aatcaaggat gttggatatt
    38701 cctgccaaga atttggaaga acatggtgtg gtgtctgaat ttacagctca gaagatggct
    38761 gagcaggcac gaagcaagac ccagtctgat tttggaatta gtttgaccgg agtggcagga
    38821 ccagatagcc tagaaggaca cccagttggg acagtcttca taggcttggc gcaagagcaa
    38881 ggaactgagg ttatcaaggt taatattgga ggcagaagcc gagcagatgt acgtcatatt
    38941 gcggttatgc atgcctttaa cctagttcgc aaggctttat taagtgacta acttttgata
    39001 taatagtaga taggtctgag gatcattaga atgtaggaga atagaatggc gaaaaaacca
    39061 aaaaaattag aagaaatttc aaaaaaattt ggggcagaac gtgaaaaggc cttgaatgac
    39121 gctcttaaat tgattgagaa agactttggt aaaggatcaa tcatgcgttt gggtgaacgt
    39181 gcggagcaaa aggtgcaagt gatgagctca ggttctttag ctcttgacat tgcccttggc
    39241 tcaggtggtt atcctaaggg acgtatcatc gaaatctatg gcccagagtc atctggtaag
    39301 acaacggttg cccttcatgc agttgcacaa gcgcaaaaag aaggtgggat tgctgccttt
    39361 atcgatgcgg aacatgccct tgatccagct tatgctgcgg cccttggtgt caatattgac
    39421 gaattgctct tgtctcaacc agactcagga gagcaaggtc ttgaaattgc gggaaaattg
    39481 attgactcag gtgcagttga tcttgtcgta gtcgactcag ttgctgccct tgttcctcgt
    39541 gcggaaattg atggagatat cggagatagc catgttggtt tgcaggctcg tatgatgagc
    39601 caggccatgc gtaaacttgg cgcctctatc aataaaacca aaacaattgc catttttatc
    39661 aaccaattgc gtgaaaaagt tggagtgatg tttggaaatc cagaaacaac accgggcgga
    39721 cgtgctttga aattctatgc ttcagtccgc ttggatgttc gtggtaatac acaaattaag
    39781 ggaactggtg accaaaaaga aaccaatgtc ggtaaagaaa ctaagattaa ggttgtaaaa
    39841 aataaggtag ctccaccgtt taaggaagcc gtagttgaaa ttatgtacgg agaaggaatt
    39901 tctaagactg gtgagctttt gaagattgca agcgatttgg atattatcaa aaaagcaggg
    39961 gcttggtatt cttacaaaga tgaaaaaatt gggcaaggtt ctgagaatgc taagaaatac
    40021 ttggcagagc acccagaaat ctttgatgaa attgataagc aagtccgttc taaatttggc
    40081 ttgattgatg gagaagaagt ttcagaacaa gatactgaaa acaaaaaaga tgagccaaag
    40141 aaagaagaag cagtgaatga agaagttacg cttgacttag gcgatgaact tgaaatcgaa
    40201 attgaagaat aagctgttaa agcagtggaa aaatccgcta ctttttcgat ttttgattca
    40261 agtttttaga ttatatatag tagcttgaaa taagatatga acaactttat taggaaagtc
    40321 aaattaattt ctagaaatgt tttagcagct acagcgtact attccaaact caaccaacta
    40381 taatagatcg aaactagaat agtacacatc tatttctaaa acattgttaa aaatcgattt
    40441 gactgtcctt atttcattcc gctatatata agtttgctgt ttcttgtcgc tcctctggaa
    40501 agctgatata atagctttat gaataaaaaa cgaacagtgg acctgataca tggttcgatt
    40561 cttccctcgc tcttaagctt cacctttcca atcttgctat caaatatttt tcaacagctc
    40621 tataacactg ctgatgtctt gattgttgga cgatttcttg gtcaagaatc cttggctgca
    40681 gtaggagcga cgacagcgat ttttgacctg attgtaggtt ttacacttgg tgttggcaat
    40741 ggcatgggga ttgtcattgc tcgttattat ggggctcgga atttcactaa aatcaaggaa
    40801 gcagtagcag ccacctggat tttaggtgct cttttgagca ttctagttat gttgctgggc
    40861 tttcttggct tgtatcctct cttgcaatac ttagatactc ctgcagaaat tcttcctcaa
    40921 tcttatcaat atatttctat gattgtgacc tgtgtaggtg tcagctttgc ttataatctt
    40981 tttgcaggct tgttgcggtc tattggtgac agtctagcag ccctgggatt tctgattttc
    41041 tctgccttgg ttaatgtggt tctggatctc tattttatta cgcaattgca tctgggagtt
    41101 caatccgcag gacttgctac cattatttcg caaggtttat cagcggttct ctgcttttat
    41161 tatattcgta aaagtgtgcc agaactcttg ccacggttta aacatttcaa atgggacaaa
    41221 agcttgtacg cggatctctt ggagcaaggt ttggctatgg gcttgatgag ttcaattgta
    41281 tctatcggca gtgtgatttt acagttttct gttaatacat ttggtgcagt gattattagt
    41341 gcccagacgg cagctcgacg cattatgacc tttgcccttc ttcctatgac cgctatttct
    41401 gcatcaatga cgacctttgc ttctcagaat ctaggagcta agcgacctga ccgcattgtt
    41461 caaggtcttc gaatcggcag tcgtttaagt atatcctggg cagtttttgt ttgtattttc
    41521 ctcttttttg ccagtccagc cttggtttcc ttcttggcta gttcgacaga tggttacttg
    41581 atagaaaatg gaagtctcta tctgcaaatc agttcagcct tttatcccat tttgagcctc
    41641 ttgttgattt atcgcaattg cttgcagggc ttggggcaga agatccttcc tctagtttct
    41701 agctttattg aactaatcgg aaaaatcgtt tttgtggttt tgattattcc ttgggcagga
    41761 tataagggtg ttatcctttg tgaacctctt atctgggttg ccatgacagt tcaactgtac
    41821 ttctcactat tccgtcatcc cttgataaaa gaaggaaagg caattttggc aaccaaagtg
    41881 caatcctagt tggatttact gaataaaatc catttcctct agtgaacatc gaaaaaactt
    41941 gtgttctctt ctttagtttg gtgttgaaaa tagtttaaca gacttttgac ttcttttata
    42001 tgatataata aagtatagta tttatgaaaa ggacatatag agactgtaaa aatatacttt
    42061 tgaaaagctt tttagtctgg ggtgttattg tagatagaat gcagaccttg tcagtcctat
    42121 ttacagtgtc aaaatagtgc gttttgaggt tctatctaca agcctaatcg tgactaagat
    42181 tgtcttcttt gtaaggtaga aataaaggag tttctggttc tggattgtaa aaaatgagtt
    42241 gttttaattg ataaggagta gaatatggaa attaatgtga gtaaattaag aacagatttg
    42301 cctcaagtcg gcgtgcaacc atataggcaa gtacacgcac actcaactgg gaatccgcat
    42361 tcaaccgtac agaatgaagc ggattatcac tggcggaaag acccagaatt aggttttttc
    42421 tcgcacattg ttgggaacgg ttgcatcatg caggtaggac ctgttgataa tggtgcctgg
    42481 gacgttgggg gcggttggaa tgctgagacc tatgcagcgg ttgaactgat tgaaagccat
    42541 tcaactaaag aagagttcat gacggattac cgcctttata tcgaactctt acgcaatcta
    42601 gcagatgaag caggtttgcc gaaaacgctt gatacaggga gtttagctgg aattaaaacg
    42661 cacgagtatt gcacgaataa ccaaccaaac aaccactcag accatgtgga tccataccct
    42721 tacttggcaa aatggggcat tagccgtgag cagtttaagt atgatattga gaacggcttg
    42781 acgattgaaa caggctggca gaagaatgac actggctact ggtacgtaca ttcagacggc
    42841 tcttatccaa aagacaagtt tgagaaaatc aatggcactt ggtactactt tgacagttca
    42901 ggctatatgc ttgcagaccg ctggaggaag cacacagacg gcaactggta ctggttcgac
    42961 aactcaggcg aaatggctac aggctggaag aaaatcgctg ataagtggta ctatttcaac
    43021 gaagaaggtg ccatgaagac aggctgggtc aagtacaagg acacttggta ctacttagac
    43081 gctaaagaag gcgccatggt atcaaatgcc tttatccagt cagcggacgg aacaggctgg
    43141 tactacctca aaccagacgg aacactggca gacaagccag aattcacagt agagccagat
    43201 ggcttgatta cagtaaaata ataatggaat gtctttcaaa tcagaacagc gcatattatt
    43261 aggtcttgaa aaagcttaat agtatgcgtt tttttgtgga gatatttcct tcaatgtttg
    43321 ctactatatt aaacaaaaat cagaaagcaa actagaaagt tatgctcaaa taaaatctaa
    43381 atttgacaat gtaaaccgag tcggatagct ttaagtactg ttttgaggtt gaagatacga
    43441 tttttgatag gaactcatca attttagatt tttaagcagc atcaataaat tgcttccttg
    43501 ttttgtcata atttttttat ttaaaaaatt atgacaagag tgtgctattc tttttatgag
    43561 aggtgtatga atatgataaa tgtatgtgat aaatgtatgt gatgttggaa aaagaataaa
    43621 agaacttaga atatcttcaa atcttactca agataagatt gctgagtatt tgtctttgaa
    43681 tcaaagcatg attgccaaaa tggaaaaagg tgaaaggaat atcacgaatg gatttaagta
    43741 ataaagcttc aaatcttaga aaaaagttgg gagctgatgg tgaatcgccg atagatattt
    43801 ttaaattggt acaaaagata gaaaatttga cgctggtatt ttatggactc ggaaagaata
    43861 ttagcggagt ctgttataaa ggaactcagt tcagtctcat tgcagtcaat tcagacatgc
    43921 cattagaaag gtaaagattt tctttagcac atggactgta tcatctttat tatgatgagg
    43981 tgaagaagag ttcagtcagt cttatcttga ttggtgaagg agatgaaact gaaagaaaag
    44041 cggatcagtt tgcttcttat tttttaattt tcccatcttc actgtatagg atggttgagg
    44101 aaatcagaga aaatgccaat agaactcatc ttgaagtaga agatattata aaattgggtc
    44161 agttttatgg tatcagtcat aaagctatgt tatatagatt gaggaatgat ggataccttg
    44221 atgcagaaga aattaaaaat atggatatta gtgttataga gacagcttca agattaggct
    44281 atgatacaag tttatatcgt cctttgtcag aaagtaaaaa agaaatggca ttaggataat
    44341 atattaattc aactgaacaa cttttagaaa ataacagaat ttcgcaaggg aagtatgagg
    44401 aactgttact agatgctttc agatatgata ttgtatatgg gctagatgaa gaggggggag
    44461 ttgtcgtttg actagtcgtg tatttattga tgcagattgt atttcagtat ttttatgggt
    44521 tggcattgaa catcttttag aaaagctcta tttgggtaaa attgttattc cacaagaggt
    44581 gtatgatgaa atcaatatac ctacaattcc ccatttaaaa tctaggatag atcagttggt
    44641 agctaagggt tcagctgaga ttgtgagcat agacattgga actgaagaat acgcattata
    44701 tagagattta acaagaaatc atgatagtaa caagattatt ggtaaaggag aaggggcatc
    44761 tatttcctta gcgaaaaagc ataatgggat attaggaagt aataacctaa gagatgttaa
    44821 accatatgta gaagaatttt ctttagaaca tatgacaaca ggagatatac tgattgaagc
    44881 gtttaaagcg taatttatta ctgaacaaga gggcaatcat atctggaata atatgcttaa
    44941 aaagagaagg aaaattggtg caaattcatt cttcgtggaa gtattcatca aaatagacaa
    45001 aaataaattt ggataaatcg aactcactat tcaggaggca tatgagcaat tcgaaaaaga
    45061 aaaatgtcaa attgagccta taggagtaga agtgaaatag taagtcctgc atagtggatg
    45121 agagaaaagt tctccttgaa gttttcctga actatcagtc gcatgtcaaa cgatatgtag
    45181 ggtaatgtga gaggggatag cgagtagttt ttggttattt tatcaaaaaa cttatatttt
    45241 attataccga atgataaaat ataataaaaa tgatagaata aggaaaaaac atgaatgtca
    45301 aaaagataat gtcaattttt caatcctttt atgttgatgt cagtattgag gaactgactt
    45361 tgactttacc aatcagtttt gtaaaaaagt ttgagtatac tcaaatgact tttcataagg
    45421 aatcattttt attgattaaa gaaaagagaa gggggagttt gagttcattt gttactcagg
    45481 ctcgcactat gggtgataaa gccaatatgg atgttgtttt ggtgttttcg aagttatcag
    45541 acggtgaaaa aaagcaatta cttcaagcta gagttccgtt tgtagacttt aagggaaacc
    45601 tcttcttccc tacattggga ctagtactga atgcgaatga tactgaagtc cctaaggaat
    45661 taatacctag cgaacaatta acgtggattg cctttttatt gccagatggc gatataaagc
    45721 agataaaatc tgtttctaac cttctatatg gtggtgctta tgctttgtcg cattcaactt
    45781 ttttagctga aacggatgaa aatactagct atgtcatatg gcagagaaaa ttcaatcagt
    45841 tatccttgcc actttctcag catgttttaa aatgaaagat gctagagata tggaaatatc
    45901 gtccttttgt atctgagttt tggaatgatt ttaaaaataa tcatgataaa caatttgtag
    45961 atccgatttc tctttatttg accttaaaag atgatgatga cccacgtata gaggaagaga
    46021 gtgaagcact agaaaatatg atattacagt atctgggaga agatgatgcc agctaatacg
    46081 aaagttattt ttcaagaaat gtttgcggat tttcagaact attatgttct gattggggga
    46141 actgctacct ctatcgtatt ggattcgcaa ggatttaaaa gtcgcacaac aaaagattat
    46201 gatatggtca tcattgatga agtaaaaaat aaggaatttt atactacctt gaatcatttt
    46261 ttagaattgg gagagtatca aggaagtcag aaagatgaga aagcgcagct ttttcgattt
    46321 acaacaacta attctgagtt tccttctatg attgaactat ttagtatctt accagaatat
    46381 ccattaaaga aggacggtcg agaaattccc ttacattttg accaagatgc tagtttatca
    46441 gccttattat tggatgaaga ttattataat atattggtgc atgaaaaaga aaccattcag
    46501 gggtattcgg tattgagtaa ttgtggtcta tactcttcga aaatctcttc aaaccacgtc
    46561 agcttccatc tacaacctca aaacagtgtt ttgagcagcc tgcagctagc ttcctagttt
    46621 gctctttgat tttcattgag tattaattat ttttaaggct aaagcttggc tggatatgag
    46681 ggaacgctct gctacaggtg ctcaaggttt aagtaagtcc attaaaaagc atttgaatga
    46741 ccttacccgt ttgacagctt ccttgctagg agatgaaaag ttatcggcta taacatcaag
    46801 tagtgcggta aaagcagaca tgcaccgctt tgtgatagaa ttagagcttg tgaagtcaac
    46861 tattcttcaa aatgatgaca tttcattaga tcaaaatgaa atttttgaaa ttctgaaaaa
    46921 ttttttcgat ggttaaaata attgtagcga gatggctata ttgaattcgt ctatacctgg
    46981 aaactagaaa aaacttcaat ttcaggagaa aatgaagtca atcttcccac aatcaaacgt
    47041 atagtatcaa ggtttttcaa gacctgatat tatgcgtttt ttgcttttca aaactttttg
    47101 cccagtcttt gtttttatcc tctagtcact tgatttgttt caggtggttt tttagtatag
    47161 taaaatgaaa cgagaacagg acaaattgat caggacagtc aaatcgattt ctaacaatgt
    47221 tttagaagca gaagtgtact attctagttt caatctacta tagttaaatc tgcggtcaag
    47281 tctactggtg aatctatgat tgtaatactc ttccaaaatc tcatcaacca cgtcagtctt
    47341 gccttgcagt ctgtatctta ctgaccaagc tagtgatgga cttagaatag gtgatttgga
    47401 gcgtcctatt ggctaggaaa tgctgatcat agtcctttgc tgaggctagg gtgtttcaac
    47461 attcaacact caactggttg atctagttga taggaaggga attactataa aatactcagt
    47521 cttccatcat attttttgaa acgattgtgt aatcaaaatg taccaattat tgtagtattg
    47581 gtacagaaga tgttgtgaat ggataaatat atcataactg ctgtctctct atgtaaaaag
    47641 aaggctgtat caaaaagatt tcatatgtct gtgcatatat ataatagact tcctgcaaaa
    47701 ctagaatcct agttcatgat tgataatacc agcactcaaa ttcattcgta atccgaagcg
    47761 tttacgatga tttcgatagg ttgttgaaaa cattttaaac gtttttactt tggcaaagat
    47821 gttctcaacc ttgcttctct ccttagatag cgcatggtta tagactttat cttcaactgt
    47881 tagtggcttg agtttgctgg atttacgtgg agtttgtgct tgaggatata tcttcatgag
    47941 cccttgataa ttactgtcag ccaagatttt accagcttgt ccgacttttt tgataagctg
    48001 tttttaatac agctaacatc tctttaaaag tggtacgctg aacactaaca agacgcttaa
    48061 atcgtgcatc agttagttgt ttacttgctt cataattcat agaactacta taccatattt
    48121 tgtttcgcag gaagtctaat aagttatagt ccagttttta ctatactttg atattcaaat
    48181 atgttatact atggttatca aagtaaatga aaggagttac gaatatgacg ccagaagaaa
    48241 tgtacctgac agagcgatta gacgtacaga tagctcattt tttaaagaaa agcgttcaac
    48301 atcgtaggcg ctataaggta ttaaaaataa cagaaatcgt ggcaggtttc ctcatagctg
    48361 tcttttgtgc tattcctatg ccaggtgatc gctaccgttt gatttcggtt gccttatcca
    48421 gtctcggctt gctgtgtgag gggattatca atttgtataa tgcaaaggaa aattggattt
    48481 cttaccaaaa aactgcgcaa ctcctggaga aagaaaaatt cctctatcaa tgccaaacgg
    48541 agaaatatgc aggaaagacc aaggcttttg ccctatttgt caagacatgc gaaggtctta
    48601 tctcagagga gattaaccag tgggaaagta tccagtcaaa agaagtggca gctagtgcag
    48661 atgctccagt taaaaaagag taggaggtag aggaaatgtc tcaatccagt tacctgtcgc
    48721 ccttgctctg gttaaaaaaa gaagccgata aggaaaagat gagcgcgacc cagtgccaga
    48781 tatttttctt ttactatcaa atgtttgagc tcttatttgc tagagaaagc gacatgaaag
    48841 acttatgtct gggaacgaaa ggtttttatt tctcgcagtt agagaaaaat ttgctttctg
    48901 gagtttcccg atttctaaaa aacttggagg ggaaagtaac tctcaaggct aaccaagaag
    48961 tatcagctcg caaagccctt tttctagcct tgacaactag ccaatcagat tggcaggagt
    49021 tagctcctgt ttttgatttt tatcagacta tcgggaggct tgaaaatcct tctctcttga
    49081 gttctcagga cagacaacat ctgatgtgga tttaccagtc agctttggag aaggattata
    49141 ttgtcaaggt tattggcgac aagcattttg tattgaagag acaagatgct actaaattga
    49201 cagcgcgcca aactcaaact ttggaaattc tgagtcaatc agaagacttg gtcaatcctg
    49261 tctatgttac attaggagaa aagggggtgc tcttgcttga ttaagagagg agatgttgta
    49321 gctctttatt tgccttttcc gactattagt agcgatttgg ctgtgaagaa tcatatgtat
    49381 atctgtattg acaacagcat gactaaaaac aaagagttgg ttaaaaatca gaccttcaaa
    49441 ccagctctct tgaccagacg tttggtcaag aactttatga tagaagagcc ggatctagct
    49501 cgtaatcctt ttacaagacc aaccttgatt gacttagata aggtatttat gttggataat
    49561 acggttattc cgacttctta tctagccaga cggcgacgca atgtctcaga agaattgtac
    49621 gaggaaattt tggatcactt agtccaacca cggctgattt cgctgaacaa gtctgagttt
    49681 atgcaactca atccaggaac ttattaggag gtagaagatg gcaaataaag cagtaaatga
    49741 ctttatacta gctatgaatt acgataaaaa gaaactcttg acccatcagg gagaaagtat
    49801 tgaaaatcgt ttcatcaaag agggtaatca gctacccgat gagtttgttg ttatcgaaag
    49861 aaagaagcgg agcttgtcga caaatacaag tgatatttct gtaacagcta ccaacgacag
    49921 tcgcctctat cctggagcac ttctcgtagt ggatgagacc ttgttagaga ataatcccac
    49981 tcttcttgcg gtcgatcgtg ctccgatgac ttatagtatt gatttgcctg gtttggcaag
    50041 tagcgatagc tttctccaag tggaagaccc cagcaattca agtgttcgcg gagcggtaaa
    50101 cgatttgttg gctaagtggc atcaagatta tggtcaggtc aataatgtcc cagctagaat
    50161 gcagtatgaa aaaatcacgg ctcacagcat ggaacaactc aaggtcaagt ttggttctga
    50221 ctttgaaaag acagggaatt ctcttgatat tgattttaac tctgtccatt caggcgaaaa
    50281 gcagattcag attgttaatt ttaagcagat ttattataca gtcagcgtag atgctgttaa
    50341 aaatccagga gatgtgtttc aagatactgt aacggtagag gatttaaaac agagaggaat
    50401 ttctgcagag cgtcctttgg tctatatttc gagtgttgct tatgggcgcc aagtctatct
    50461 caagttggaa accacgagta agagtgatga agtagaggct gcttttgaag ctttgataaa
    50521 aggagtcaag gtagctcctc agacagagtg gaagcagatt ttggacaata cagaagtgaa
    50581 ggcggttatt ttagggggcg acccaagttc gggtgcccga gttgtaacag gcaaggtgga
    50641 tatggtagag gacttgattc aagaaggcag tcgctttaca gcagatcatc caggcttgcc
    50701 gatttcctat acaacttctt ttttacgtga caatgtagtt gcgacctttc aaaatagtac
    50761 agactatgtt gagactaagg ttacagctta cagaaacgga gatttactgc tggatcatag
    50821 tggtgcctat gttgcccaat attatattac ttgggatgaa ttatcctatg atcatcaagg
    50881 taaggaagtc ttgactccta aggcttggga cagaaatggg caggatttga cggctcactt
    50941 taccactagt attcctttaa aagggaatgt tcgtaatctc tctgtcaaaa ttagagagtg
    51001 taccgggctt gcctgggaat ggtggcgtac ggtttatgaa aaaaccgatt tgccactagt
    51061 gcgtaagcgg acgatttcta tttggggaac aactctctat cctcaggtag aagataaggt
    51121 agaaaatgac tagtagagga gaatgcttgc gacaaaaaga ggcgatgatc tctctgcgga
    51181 tatctgaaag tttatctctt gcctagcgat ttccattgga gtatgctcgt gatgttaaaa
    51241 tgaatctatc aaacagaatg tgtaaaaaag taaaaagggt agccaattcc ttgatataca
    51301 ggggattgat tatcctttac ttgttttaga tgattggaaa ttcaagaatg acacgtatcg
    51361 gaaatatttt gctgtttata tctaataccc atttatggaa aaaatgaaat taaatatgaa
    51421 caaatcaatt gctagcaatg gtttagaagt gccagtgtac tagtctaatt tctccatctt
    51481 gggaacacgt aaattatact cttcgaaaat ctcttcaaac caggtcagcc ctatccgcaa
    51541 cctcaaaaca gtgttttgag caacctgcgg ctagctttct agtttgcttt ttgattttta
    51601 ttgagtatta gaggtttgct tagaaactct tctattgatt tcttagaata caatagcgcc
    51661 tataagaact gttggatttc aaagtattta cttgaactat gatatgtctg gagtagactg
    51721 tcaacaaaag gtgcagtatg attgtttttg tcgcttatat ctacaaactt caaacagtaa
    51781 tttgagctga ctttgtcaaa cttggctgaa actttctatt tgcagataat ggtctagttt
    51841 gttttttgaa tgtggatgag tgtctgttga taaagataga aaggtaagac catcttagca
    51901 ggtaaagtgc tatcctagct tgatttgcta ataaaatcca tttcctctag tgaaaatcaa
    51961 aaaaacttgt gttataataa gaaagattaa aatgtgaaaa aaggagattc ctaatgggac
    52021 gtaaatgggc caatatcgta gccaagaaaa cggctaaaga tggagctaac tctaaagtat
    52081 atgcaaaatt tggtgtagaa atctatgtag cagctaaaaa aggtgatcca gatccagaat
    52141 caaactcagc tttgaaattc gttatcgacc gtgctaaaca agcccaagtg ccaaaacaca
    52201 ttatcgataa agcgattgat aaagccaaag gaaacacaga cgaaaccttt acagaaggac
    52261 gttacgaagg ttttgggcca aatggctcta tgctaattgt ggatactttg acttctaacg
    52321 ttaaccgtac agcagccaat gtccgtgcag cctttggtaa aaacggcgga aacatgggcg
    52381 cttcaggttc tgtttcttac ctttttgaca acaaaggtgt tattgtattt ggaggtgaag
    52441 atgcggacgc agtctttgag caattgctcg aagcggatgt ggatgtggat gacgtagaag
    52501 cacaagaagg tacaatcaca gtttacacag cgccaactga ccttcacaag gctatcgttg
    52561 ctctccgtga gtctggtatt gaagaattcc aagtgactga attggaaatg attcctcagt
    52621 cagaagtgga attgtcaggc gaagaccttg aaacctttga aaaactttac agcgttcttg
    52681 aagacgacga agacgtccaa aagatttata cgaacgtaga tgggttttaa tttaacctat
    52741 agaacatgat cctaagtgag aaaatcactt gggatttttt taatcaagaa aatagttctc
    52801 atagaaattt aattattctc cagagaacta tttttattta gaagggggag attatggata
    52861 aaccgatgtt agtctttaag cgttttggtc atcaaattta cctgatggtg caaaaggaag
    52921 ccaaacgttg cggcattgaa tttatgggtg ggccgcaagg tcaggttgtg cgttttttgg
    52981 ataatcgcga gaaaaaccaa gacttggtct tgattaaaga tatcgagcag gaactcaata
    53041 ttaccaagtc tgttgctagt aatctggtta agcgtatagt gcaaaatggt ttggtggaat
    53101 tggaggcgag tcctgttgat aagcgggcta agtttgttcg tctgacggac aaagcacgtt
    53161 ctcagatgca acaggttaag gcttttttga acgcatagac aagcagttga tggaagacat
    53221 tgatgaagat gaattactga tttttgagaa agttctcggt caactacagg caaatatcaa
    53281 gggaatagga ggagagaata aagaaattag ccaaaagaat tagtagaaaa gaatggggga
    53341 tgattttact agccattctc tttacttgct tttcggtcta tctagagttg gaagtgccga
    53401 cctatatctc gaaaattacg gatttgctag gtagtcaagg aactaattta gatgagttgt
    53461 ggcagccggc aagcatgatg atgggaatgc cctttcttgc cttcttgtcc gtagttgcag
    53521 ttggattttt tgcatcccga gtggcggctt cttatactag taggctgaga agtgatattt
    53581 ttaaccgagt tttggattac tcgcagacag agattaagaa attttcaatt cctagcctct
    53641 tgatgcgtac taccaatgac attactcaag ttcaaatgtt gattactatg gacttgcaag
    53701 tggtaacgtg tggtccaatt atggctatct gggctattgg gaagatttta ggtcattcag
    53761 aatactggct ctgggccgta cttgtggcag tgattgtcaa cgtcctgatg acgaccgttt
    53821 tgatgacgct agcctttcca aaacagtcct tgattcaggg gctgacagat aaactgaaca
    53881 gtatcactcg tgagagttta acaggtattc gtgtcgttcg tgcctacaat gcagaggatt
    53941 atcaaaatga aaaatttgca gcagtaaatg atgaattgac ccgttaaaat ttgtttgtca
    54001 accgtcttat ggctattttg aatcctatca tgatggggat ttcaagtggt ttgagtgtgg
    54061 cgatttactg gattggggcc tatgtgatta acgacgctgc tccgatagcg cgtctgcctt
    54121 tctttagtga catgattgtt ttcatgtctt atgccatgta ggttgtcatg gacttccttc
    54181 tcatgggagc actcttcatc gttcttcccc gaactatggt ctctgctaag cggattaatc
    54241 aagttttaga tttgcattct tctatccaaa accctgctca agtgcagctg actgatgaaa
    54301 acttcaaagg tcaggtcgag tttaaggatg tgaccttccg ctatgcggca aattcggagg
    54361 cagttattga acatgttagc tttaaagcag aaactggtca aacagtggcc tttattgggt
    54421 caataggttc tggtaaatca actctggtca atctgattcc acgtttctac gacgtgtcag
    54481 caggagaaat tctggtggac ggtgtcaatg ttcaagacta tgacttctct gcgacagctc
    54541 atgctggtca aagggttgcc attgttgggc cgactggggc tggtaagaca accattgtca
    54601 atcttttgat gaaattctat gagattgata agggaagtat tcgcattgat ggtgtggata
    54661 ccaaggctat gacgcgttca gaagtgcatg atgccttttc aatggtcttg caggatacct
    54721 ggctctttga aggaactatt cgagacaatc tcatctataa tcaaataggg attagtgatg
    54781 aacgaatgat ggaagctagt aaggctgtgg gaattcacca ctttattatg accttgccag
    54841 atggctatga taccatcttg gatgacaccg tgaccttgtc tgtaggacaa aaacaactat
    54901 tgactattgc tcgtgccctt cttaaggatg caccgctttt gattttggat gaggcgactt
    54961 cttctgttga cacacggaca gaggaattga tccaaaaagc catggaccgt ttgatggaag
    55021 gacgcacatc ctttgtcatt gcccaccgct tgtcaaccat ccgaaatgca gacttgatct
    55081 tggtcatgaa agatggaaat atcatcgagc aaggcaacta tgaggaactg atggtgtaag
    55141 gtggcttcta cgctgacttg tacaatagtc aatttacaga agatgaagca gaagaataaa
    55201 tcaaaagaag gcttgacggc cttctttttc ttatttatac tagtacacat agaaagagag
    55261 aagtatgagt cagaaattat acaatatgaa atttgctgct gtctacttag ccttgattgc
    55321 aaaagttgag cgaaagggtg gaaaggcaga gtcagttcac caagtgacca gttggttgac
    55381 agggtatgaa gtgagtgacg ttcttacttg tctggatagg gatgttactt acggagattt
    55441 ttttcgacaa gcaccatatt atgtccctga acgaattgca attacaggga agatttgcgg
    55501 tgtccgtatt gaggaaattg atgatcctct gatgcaggaa atacgtcgct tggacaagct
    55561 agtggattgg cttgccaagg ggaaaacatc tcaacaagtt ctagaaaagt atgagaagca
    55621 taaatgaaaa attatcaaga atggtatcga aatatcagat ccagactaac tagtcgtcca
    55681 attcttttat tcctattacg cagtttcaat cgtttgatga cagtcgccat gcccctggtc
    55741 tatctgatct tgctagtcac cacttacctg caactaggac ttggtcagca agttggagtt
    55801 tatgtgctta ttcctgcatc aggttttgtg gccttgtccc tgtttcgtaa aaaaatcaat
    55861 cacccgagac cttatgaaac ttgggatatc tgtccccttc ttgataagga tagttcggga
    55921 cggtcgatgc ccagtcgcca tgtcttttct gcaactatca tctccatggc ctgtctgcat
    55981 gctagtctac ctattggctt agtatgcttg atcttttcag ctttgctggg gttggtgagg
    56041 gttttagggg gtgttcatta tcccaaggat gtcttggttg gctatgcttg tggtctggtg
    56101 tggggattcc ttttcttctt attctgacat gtaagttaag ctagtcctac aaccacttac
    56161 tgcttcaaat tgaccacttg cttttttgcc cttgtattcc taacttagct ttgatatagt
    56221 agagtcagaa aggagatgtg atgaagttac gaattgagat tgacggcaat ttagaggaga
    56281 ctgaaattgt catcaagacc cccactttga cagatgaaat tgcagacttg caacggctct
    56341 tgcaagaatc caagtctcct aggttgattt tttacaaggg gacgggtgaa tattatctgg
    56401 acttgtcgga aattctcttc tttgagacag aaggtagcaa gatttatgcc catacccaga
    56461 aaaatgccta cgaagttcgg ctcaaactct atgagttaga ggctatcctt cctcgctatt
    56521 ttagtcgagt atccaagtca acgatcgtta atattcggca aatctattcg gtggacaagt
    56581 ccttttcagg aacgggcacc atttcctttt atcaaaccca caaggaggtt catgtgtcac
    56641 ggcattacca atccctccta aaagaaaatc taagaaatat gaggtaagaa catgaaaaag
    56701 aaagcatttg gtattgtgtt gcttgtacta gcagctttaa tattagtaca aggaaatttt
    56761 ggaatccctt ctctaggagg gcacatttgg cccttgattg gtattgcttt ttttgcctac
    56821 caatcagttg gagctttgtt gcgtcgccac ttaacttcag cctcttttac agctctagta
    56881 gccttaatga ttgctaacca cttttatggc attttaccga ttccaaacca gacactaatc
    56941 tgggcaggag ttctaatcgt tctcggagta aatatgttga ctcattctaa cagaacttgg
    57001 aatgggaaaa aatggtggta tgatggtgaa aaaaacattc ttatagataa ggaagttgct
    57061 tttgggacag ggactttcta caagcaagac caagaattgg tagaagacca agtagaagtt
    57121 ggttttggca atgcaaaaat ctactatgac aatgcagaga tgttaggtga ttttgcaact
    57181 ttaaatattg aagtagcttt tggtaatgca actgtctatg ttccgcaaca ctggcgtgtc
    57241 gatttgaaag tagaaacatc ctttggtgca gccaaggcgg acgctcctgt agccccaacc
    57301 agcaaaacct tgattatccg tggagatgtg gcttttggga agttggaaat tgtctacgct
    57361 aaataaaaaa atcttcactt caaccatcaa aataggcgta ctaagagtag gaaattgatg
    57421 ccttgctctg atttcagttc tatggttgtt agactttaaa aaatgaaatg ctgcctttaa
    57481 aagttgtata tttttcgata ttttggcttt tacgtttgat gtatctatgt actacagcgt
    57541 agatgatgta gtgtcgaatg cttttaaaaa acgaatgata ttggacagtt tttttgcctt
    57601 taattgctca ggaaccatga aagtcagtac ttgggtttat gacaagggag aatggtatta
    57661 tgtaagttct tctggttcca tgattgcgaa tgattgggtc aaagacaatg gcaagtagta
    57721 ttatctggct tcatcaggta agatgcttcg caatacctac acacctgatg gttactacgt
    57781 tggcaactta ggtgcctggc aataagaata atactctttg aaaatctctt caaaccacgt
    57841 caacgtcgcc ttatctacaa cctcaaaacc gtgttttgag cagcctgcgg ctagctttct
    57901 agtttgctct tagtataaga agtccttttc cttaaaggaa gaggcttttt acttgctttt
    57961 ctgctgcttc ctcatttgtc ctgaagcctt ttttgtgtta aaatgaatgg tatgaaagct
    58021 aaaaaaatgt ggatggcagg cttggctctg ctaggtatcg gaagccttgc tcttgctacg
    58081 aaaaaagttg cagatgaccg taagctcatg aagactcagg aagagttgac agagattgtg
    58141 cgagaccatt tttccgacat gggggaaatt gcgacccttt atgttcaagt ttacgaaagc
    58201 agtctggaga gcttggttgg tggcgtcatt tttgaggatg gccgtcatta tacctttgtc
    58261 tatgaaaatg aagacctagt ctatgaggag gaagtcttat gatacagcca gcaagtttag
    58321 aagaattagc atctttagtg gaaaaagcgg gcaagaaggt cttccttttt gtggcagact
    58381 ggtgtggcga ttgtcgttat atttatcctg ccttaccaga gattgaagag accaatccag
    58441 agttcacctt tattcgaatg gaccgagatc agtatatgga tttggccaaa ctctgggatg
    58501 tttacggaat tcctagcctt gttgttctag aaaaggacaa ggaaatcggt cgttttgtca
    58561 atcgcgaccg taaaagtaag gagcaaatta acgatttttt agcaggattg aaataggaga
    58621 aaaaggaaac aatgattttt acgtataaca aagaacatgt cagtgatgtc cttatggtca
    58681 tcgtgaaaaa tagcggagat gccaaactga atgtggaacg caaaggcaag gtagcccgtg
    58741 ttttcctcaa agaaaatggg gaaacagtag cttggaacat ttttgaggtt tcgagcttgt
    58801 ttgaaattgc agagcgcggt caagtctttt tatcagatga gcaagtcgct cgtttgaacc
    58861 aagaattaca ggcggaaggt tttacagaag aaattgttaa tgataaggaa cctaagtttg
    58921 ttgttggtga aattgtcgag atggtagctc atccagacag tgaccacctc aacatctgcc
    58981 aagttgcagt cgcaagtgac aagatagtgc aaatcgttgc aggagcacct aatgcgcgtg
    59041 ttgggttgaa aaccattgtg gctcttcctg gtgccatgat gccaaaaggg aatttcattt
    59101 tcccaggcga acttcgtggt gaaaagagtt ttgggatgat gtgtagtcct cgtgaattgc
    59161 atttgccaaa tgctccgcaa aaacgtgggg tgcttgaatt atcagaagac caagttgtcg
    59221 gaacaccgtt cgacccagcg aaacactgga ctgcctagga acttgtcagc atctgataga
    59281 aggaaataag atggcaaaaa atgtagtgat tacgggagca acctcaggaa tcggtgaagc
    59341 gattgcgcgt gcttatctgg agcagggtga ggatgtcgtt ctaacaggac gacggataga
    59401 cagattagaa atcctcaagt cggagtttgc agtaagcttt ccaaatcaaa ccgtctggac
    59461 ttttccacta gatgtgacgg atatggtcat ggtgaagact gtttgctctg atattctaga
    59521 aacgataggg aggattgata tcttggtcaa caacgccgga ctggctcttg acttggctcc
    59581 ctatcaagac tatgaggagt tggatatgtt gaccatgttg gataccaatg ttaaaggtct
    59641 gatggcggtt actcgctgtt tcttgccagc aatgataaaa gtcaatcaag gtcatattat
    59701 caatatgggg tcaaccgcag gaatctacgc ctatgctggt gccgctgttt actcagctac
    59761 caaggctgcg gttaagacct tttcggatgg actgcgaatt gataccatcg caacggatat
    59821 caaggtgaca accattcagc ctgggattgt cgaaacagat ttctcaactg ttcgttttca
    59881 tggtgataaa gagcgagctg cgtccgttta ccaaggaata gaagccttgc aagctcagga
    59941 tattgcagac acagtagtct atgtgaccag tcagcctcgc cgtgttcaga ttacagatat
    60001 gaccattatg gccaatcaac aggcgacagg tttcatgatt cataaaaaat aagaaatttc
    60061 ctcgaaaagt tacaaatttc tgtaactttt tttgatttcc tacgaataga taagtaggag
    60121 gaagaaaata tgtataataa agttatcatg attgggcgtt taacgtctac accagaattg
    60181 cacaaaacca acaatgacaa gtcggtagcg cgagcaacta tcgctgtgaa ccgtcgttac
    60241 aaagaccaaa acggtgaacg tgaagctgat tttgtcaata tggtcctatg gggcagacta
    60301 gcagaaactt tggcaagcta cgcaaccaaa ggtagtctca tttccgttga tggagaattg
    60361 cgtacccgtc gctttgagaa aaatggccaa atgaactacg tgaccgaagt acttgtaaca
    60421 ggattccaac tcttggaaag tcgtgctcaa cgtgccatgc gtgaaaataa tgcaggccaa
    60481 gatttggcag atttagtctt ggaagaggaa gaattgccat tttaatactc ttcgaaaatc
    60541 tcttcaaacc acgttagctt tatccacaac atcaaagcaa tgctttgagc agcctgcggc
    60601 tagcttccta gtttgctctt tgattttcat tgagtataaa cattaaaaag tctgagttgg
    60661 tctcaggctt tttatcttga gaaagtcaga cttttttctt gattatttct gactaagtga
    60721 tacaatagaa ctatgaatta gcactcaggt ataaagagtg ctaataatat ctatctcatt
    60781 atggaggaaa tcagatgttg aaaccattag gggaccgtgt ggtcttaaaa atagaagaaa
    60841 aagaacaaac cgttgggggc tttgttctcg caggttcagc ccaagaaaaa accaaaacag
    60901 cccaagttgt ggctactgga caaggtgttc gtaccttgaa cggtgacttg gttgctccaa
    60961 gtgttaaaac tggagaccgt gtcttagttg aagcccacgc aggtcttgat gtcaaagatg
    61021 gcgatgaaaa gtacatcatc gtaggcgaag ctaacatctt ggcaatcatt gaagaataga
    61081 aggagaaagt aagtatgtca aaagaaatta aattttcatc agatgcccgt tcagctatgg
    61141 tccgtggtgt cgatatcctt gcagacactg ttaaagtaac cttgggacca aaaggtcgca
    61201 atgtcgttct tgaaaaatca tttggctcac cattgattac caatgacggt gtgactattg
    61261 ccaaagaaat cgaattggaa gaccattttg aaaatatggg tgctaagtta gtatcagaag
    61321 tagcttctaa aaccaatgat atcgcaggtg acggaactac gactgcaaca gtcttgaccc
    61381 aagctatcgt ccgtgaagga atcaaaaacg tcacagcagg tgcaaatcca atcggtattc
    61441 gtcgtgggat tgaaacagca gttgccgcag cagttgaagc tttgaaaaac aacgccatcc
    61501 ctgttgccaa taaagaagct atcgctcaag ttgcagccgt atcttctcgt tctgaaaaag
    61561 ttggtgagta catctctgaa gcaatggaaa aagttggcaa agacggtgtc atcaccatcg
    61621 aagagtcacg tggtatggaa acagagcttg aagtcgtaga aggaatgcag tttgaccgtg
    61681 gttacctttc acagtacatg gtgacagata gcgaaaaaat ggtggctgac cttgaaaatc
    61741 cgtacatttt gattacagac aagaaaattt ccaatatcca agaaatcttg ccacttttgg
    61801 aaagcattct ccaaagcaat cgtccactct tgattattgc ggatgatgtg gatggtgagg
    61861 ctcttccaac tcttgttttg aacaagattc gtggaacctt caacgtagta gcagtcaagg
    61921 cacctggttt tggtgaccgt cgcaaagcca tgcttgaaga tatcgccatc ttaacaggcg
    61981 gaacagttat cacagaagac cttggtcttg agttgaaaga tgcgacaatt gaagctcttg
    62041 gtcaagcagc gagagtgacc gtggacaaag atagcacggt tattgtagaa ggtgcaggaa
    62101 atcctgaagc gatttctcac cgtgttgcgg ttatcaagtc tcaaatcgaa actacaactt
    62161 ctgaatttga ccgtgaaaaa ttgcaagaac gcttggccaa attgtcaggt ggtgtagcgg
    62221 ttattaaggt cggagccgca actgaaactg agttgaaaga aatgaaactc cgcattgaag
    62281 atgccctcaa cgctactcgt gcagctgttg aagaaggtat tgttgcaggt ggtggaacag
    62341 ctcttgccaa tgtgattcca gctgttgcta ccttggaatt gacaggagat gaagtaacag
    62401 gacgtaatat tgttctccgt gctttggaag aacctgttcg tcaaattgct cacaatgcag
    62461 gatttgaagg atctatcgtt atcgatcgtt tgaaaaatgc tgagcttggt ataggattca
    62521 acgcagcaac tggcgagtgg gttaacatga ttgatcaagg tatcattgat ccagttaaag
    62581 tgagtcgttc agccctacaa aatgcagcat ctgtagccag cttgattttg acaacagaag
    62641 cagtcgtagc caataaacca gaaccagtag ccccagctcc agcaatggat ccaagcatga
    62701 tgggcgggat gatgtaagca ttctatagaa aacaacttat aaaaaacaca aaaggaggga
    62761 atgactaacc cttcttttta taatattcac ttctaaattg atttgagctc tcctaactta
    62821 tatgataaaa taagactaga aaaaggagaa gaacatgatc gatgtagaaa aaattctgtg
    62881 caagatgccc cccaatcaga agattaatta tgaccgtgtc atgcagaaaa tggtagaagt
    62941 atggtagaaa aatgagcaac ggccaaccat tctcgtgcat gtttgctgtg ccccttgtag
    63001 tacctataca ctagaatatt tgaccaagta tgcagatgtg accatctatt ttgccaattc
    63061 taatatccat cccaaggtag aataccataa gcgggtctat gtcaccaaga aatttgttag
    63121 tgattttaat gagcggacag gaaatacggt tcagtaccta gaagctccct acgaacccaa
    63181 ttaataccga aaactagtta ggggactaga ggaggagccc gaaggtggcg accgttgcaa
    63241 ggtttgtttt gactaccgac tggataaaac agcgcaagtg gctatggact tgggctttga
    63301 ctactttggt tcagccttga ccatcagtcc tcataagaat tctcaaacca tcaacagcat
    63361 cggaatcgat gtgcaaaaaa tttacacgac ccactatctt cccaacgatt tcaagaaaaa
    63421 tcaaggctac aaacgttcag tagagatgtg tgaggagtat gatatctatc gtcaatgtta
    63481 ttgtggctgc gtctatgcag cccaagccca gaatattgac ctggttcaag ttaagaagga
    63541 cgctacagca ttcttgttgg gtaaggatgt tgagaaagac tattctcata tcaaatttat
    63601 agtagattga aactagaata gtacaccttt acttctaaaa cattgttaga aatcgatttg
    63661 actgtcctta tttcatttta ctatactatt acgaaattag atatataaat gaaaacttgc
    63721 ctcaaggtag gtttttttgc tagtagaaaa gcgatagaca gaaattgttg gactcttaaa
    63781 aaaatgaagt tttgctcaaa agagcttctt aaattaaaac gagcaattat cagttcaaat
    63841 ctgtttcaaa agaagaacgg ataaattaat cgatgctttg tttttgagtt aggaagttaa
    63901 gcatgccaaa ctgagtcgta ggaataaatc tctttctagt aatgtgttgt aactctgcta
    63961 taatggattt attccttttt gtgtttacac aatttatttt atactaccaa aaaaacaagg
    64021 tcaggatttt gttcctgacc tttgacaact ttaccgattc tttagttcta catagcgctt
    64081 gtaccaaatg tttacatagg cttctgagaa aggaccacgt ccattgttaa tccaatcaac
    64141 aagaattttg acatgttctt ttaaaatata gtccaagtca tcagaataat tcattttgcg
    64201 tttgtgacgc tcgtactctt caacgtccaa gagacgtttt tccccatctg taaaaatttt
    64261 aacatccaaa tcgtaatcaa tatacttcag tgcttcttca tccagatagt aggggctagc
    64321 catattgcaa tagtaagaag ttccattatc acgaatcatg gcaatgatat taaaccaata
    64381 tttcttgtga aagtaaacaa tagccggttc tcgagtgacc caacgacgac catcactttc
    64441 ggtaacaagt gtatgatcgt tgacaccaat aatggcgttt tctgttgttt ttagtaccat
    64501 ggtgtcccgc caagttcggt ggagactccc atcatgctta taactttgaa ttgtaataaa
    64561 gtcgccttct tttggaagct tcataactaa ccaactttct acaatttata agtttatcat
    64621 ttactattgt accataaaat tacctaaaat ctgtgaattt cacttggaaa tattaaagat
    64681 attctctaag agcgcttgct atatccgaaa aatcgtagcc ctttcgtgct aaaacttgag
    64741 ttaaacgctg cttcagttcg tatccttcat actttcgagc atacttacta tattgtttat
    64801 caagttcctt gaagatgagt tcttgagtcg tttcttggtc aacttggcta tctaagtcgt
    64861 caaaggcaat tttagcatca gaataagaga agcccttgtt agtcaagttc tggataatct
    64921 tatcttgcag ggcacgagat ggaagttttc cctcatattt tttcaatagt ttattagcta
    64981 cacgttgagc aacttcagaa aaatcaaatt ctttcaagtt ctcttctata gtagattttg
    65041 aaatcccttt ttgagctagt ttctgagtca gcacataagg acccttgtct cctgaaagtt
    65101 gattggtatt gatgatagca taagcgtact gaccatcatt aatccactta tcttctttaa
    65161 gattagcaat aacttgagaa acgatgtttt tatcaatatc gtattttttc agatattctc
    65221 tgacttcttt ttcagtgcgt gctttaaagg ataagtggta gagagcgaga ttcttaccat
    65281 aagaaaactg ggcaaaatcc tgaatctcgg tcagttcctc tttactaatg accttatctc
    65341 gagacagcat aaaacggaca atggtatctt ccgtgatata agaggtttgc tgtccatcta
    65401 gttccatcaa gtagagacgt tttttctttt caagttttgt gattttcata atttcctttc
    65461 atctaaatgc ttcgaaagct gcaacaagtc gtagtttatc catatttaca tattctctac
    65521 cgtaatagtc gagaaataat tcagcatacg tagcatcttg taggttgtaa tgaagggacc
    65581 aaattgccca aaagaggtcg atatgtcggt cactaaaacc agccaatccc aagtcaataa
    65641 agcaagaaaa atgagaggca tccttcaaga tgaaatttgg caggcaggca tctccatgaa
    65701 taaaagcatc agctttgaga atgtaacctt tctcttgtat cagttggtaa gcttcttcac
    65761 gactgtgaat gtgaaattga ggcagaagag tcttgttata aaaagtcccc ttctgatagt
    65821 tttttaaggc tttttcttta taacgcttca gatgattttc cgacggaaaa gattgtggtt
    65881 taagactgtg aagtttgttt aatgcttgag ccagggtttg acagagtctt tcgggttgat
    65941 ttaaaaaagc gagagcgttg ctgccaatgg cttctttagt cagaaggaag tccttatttg
    66001 ctgataaata ggtaatcact ggagttccca atccttcagt ttcgaaccaa cttgcaatct
    66061 tagtttcttg agctaatctg cctttttgat ctatttttaa atagtaacct gaatctatat
    66121 ataggacagt tgcacttgaa tgagaagaac tatcagagag attagctccc ttgatatagc
    66181 ttcgtaattg ttcagggaaa tctagtatac taaagcgagg tgtttttgaa ttcatgcttt
    66241 tattgtaaca tattcttaaa tatcttagaa actccatggt ataatagaca tatgaatctg
    66301 aaagtgaaac aaaaaatacc attaaaaatc aagcgcatgg gaattaacgg tgagggaatc
    66361 ggcttttacc aaaaaacatt agtctttgta ccaggagctc tcaaaggcga agatatctat
    66421 tgtcagatta cttctattag acgcaacttt gttgaagcaa aattactgaa ggtcaacaag
    66481 aagtctaaat ttcgaattgt gccatcttgt actatttata atgaatgcgg aggctgccaa
    66541 atcatgcacc tgcattatga taagcagctg gagttcaaga cggacttact tcatcaagcg
    66601 ctgaaaaaat ttgctcctgc aggatatgaa aattatgaaa ttcgtctaac tattggaatg
    66661 caggaaccaa aatattacag agctaagtta caatttcaga ctcgaaaatt taaaaatcag
    66721 gtcaaggcgg gcttatatgc acaaaactct cactatttag tagagttgaa agactgcctg
    66781 gtacaagata aggaaaccca agtgattgct aatcgcttag cagaattact tacttatcac
    66841 cagattccaa tcacggatga gagaaaagtt ctaggtgtcc gtactattat ggtccgacgc
    66901 gcgagaaaga ccggacaggt tcagattatt attgttacaa accgccagct taatttaact
    66961 caattggtaa aagagttggt taaagatttc ccagaagttg tgacagtagc tgttaataca
    67021 aatacagcta aaaccagtga gatatatggt gaaaagacag agattatctg ggggcaagag
    67081 agtattcaag aaggtgtact caattatgaa ttttcactat cccctcgagc tttttatcaa
    67141 ctaaatcctg agcaaacaga agtcctctat agcgaagcag taaaagcgct ggatgttgat
    67201 aaagaaaacc atttgattga cgcttattgt ggagttggaa cgattggatt tgcctttgca
    67261 aagaaagtaa aaacactcag aggtatggat attattccag aagctattga agatgccaag
    67321 cgaaatgcta aaagaatggg atttgacaat actcattatg aagctggaac ggcagaagag
    67381 attattcctc gttggtacaa ggaaggctac cgagcagatg ctttgattgt tgacccacca
    67441 cgtacaggtc tggatgataa gttattagat actattctta cttatgtacc agaaaaaatg
    67501 gtttatattt cttgtaatgt ttcgaccttg gctcgtgatt tggtacgctt agtagaagtc
    67561 tatgatcttc attatatcca gtcggtcgat atgttcccac atacagctcg aactgaagct
    67621 gttgtaaaat taataaaaaa agtttaaaaa agg
//
LOCUS       DAVBOG010000005        62379 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.005, whole genome shotgun sequence.
ACCESSION   DAVBOG010000005 DAVBOG010000000
VERSION     DAVBOG010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 62379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62379
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.005"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(141..1010)
                     /locus_tag="VQ865_000292"
     CDS             complement(141..1010)
                     /locus_tag="VQ865_000292"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000692406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HET3134715.1"
                     /translation="MKIIVPATSANIGPGFDSVGVAVTKYLQIEVCEERDEWLIEHQI
                     GKWIPHDERNLLLKIALQIVPDLQPRRLKMTSDVPLARGLGSSSSVIVAGIELANQLG
                     QLNLSDHEKLQLATKIEGHPDNVAPAIYGNLVIASSVEGQVSAIVADFPECDFLAYIP
                     NYELRTRDSRSVLPKKLSYKEAVAASSIANVAVAALLAGDMVTAGQAIEGDLFHERYR
                     QDLVREFAMIKQVTKENGAYATYLSGAGPTVMVLASHDKMPTIKAELEKQPFKGKLHD
                     LRVDTQGVRVEAK"
     gene            complement(1012..2298)
                     /locus_tag="VQ865_000293"
     CDS             complement(1012..2298)
                     /locus_tag="VQ865_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine dehydrogenase"
                     /protein_id="HET3134716.1"
                     /translation="MTVKIALLGFGTVASGVPFLLKENGGKINQSAHSDIKVAKVLVK
                     DEDEKNRLLAAGNDFNFVTNVDDILSDQDITIVVELMGRIEPAKTFITRALEAGKHVV
                     TANKDLLAVHGAELLEIAQANKVALYYEAAVAGGIPILRTLANSLASDKITRVLGVVN
                     GTSNFMVTKMVEEGWSYDDALAEAQRLGFAESDPTNDVDGIDAAYKMVILSQFAFGMK
                     IAFDDVAHKGIRNITPEDVAVAQELGYVVKLVGSIEETSSGIAAEVTPTFLPKAHPLA
                     SVNGVMNAVFVESIGIGESMYYGPGAGQKPTATSVVADIVRIVRRLNDGTIGKDFNEY
                     SRDLVLANPEDVKANYYFSILALDSKGQVLKLAEIFNAQDISFKQILQDGKEGDKARV
                     VIITHKINKAQLENVSAELKKVSEFDLLNTFKVLGE"
     gene            complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ865_000294"
     CDS             complement(2449..3186)
                     /gene="mecA"
                     /locus_tag="VQ865_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HET3134717.1"
                     /translation="MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAI
                     LDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKIDQNLDFEDLSDLPDMEELAQMS
                     PDEFIKTLEKSIADKTKDDIEAIQSLEQVEAKEEEQEQAEQEAESKKEPYIYYILSFA
                     KLADLVAFAKTVTFEMETSELYKMNERYYLTILVDIENHPSPYPAWLLARMREFADDS
                     DISRSVLQEYGQVLMSHDAVLNLQKIG"
     gene            complement(3386..4420)
                     /locus_tag="VQ865_000295"
     CDS             complement(3386..4420)
                     /locus_tag="VQ865_000295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000461501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3134718.1"
                     /translation="MFEHYSVADLFANLYKKRKANILALIALFALIAVPFTIKAVRNK
                     NTVKDTTSYSTYLIYKITPPKESAKTILNHQIGGYSDFYGKLIDGNLNGAYLFNDVEP
                     SELKKIASELDTTETTLKNSTNDYWWKKLTVYYMIDDAGVGVKILTSSKDANDLLEKK
                     IDGLIEKFKHAYANVKIEKLETINSKELNANGETALGLNVKNLILRLVVIGVVCVILV
                     VMGNVLVYLFNPTINRVGDFSQYQIDFVTEITTIANLADVLSYKNTGQELTIVSSNKA
                     ILDKLKQSQEALKGMHFVDLQDVSSLLERDTVLLVEEYGVTRYKKFEQSLQILRNLNR
                     SILGVATFKL"
     gene            complement(4449..5882)
                     /locus_tag="VQ865_000296"
     CDS             complement(4449..5882)
                     /locus_tag="VQ865_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen polysaccharide polymerase Wzy family
                     protein"
                     /protein_id="HET3134719.1"
                     /translation="MIDGKRLLFSLTIVSYTLTLVSGIVYLFNNNNVSLLSTLLFLLV
                     SSLIACWNDIKYYLIHFIFYLTIFVFLVSRPTIDYFRDGALDTYHPIAYRFAFIVVMV
                     SILGLTTGGVLARYFIARKKIKVANIGNSLKEVYIKRLRFVSLGVFLLTYPFYFIRLF
                     ERLLYRLQTSYYAYYANFESKLPYFTYILSTFTVYAMCMYLATKPKKLQATAVLVSFI
                     AANTIHLAIGTRNPFILSILFAFVYYFMREQTEKGKWIGFKEKLAIFVGSPILMLAMG
                     VLNYVRDNVQVSHTGFWDILLDFIYKQGTSFGVLARGFLFNSSLPYRDFRNFTFGPVL
                     DYFARGSLGAIFGGKAFEHTTNSVELAIDSNSYAHNLSYLVLNKEYLKGHGIGSSYIM
                     ELYTDYGMIGVFLLSFLLGVLFIAMLQVAYRSRTILFALSLLILNNLFFMPRSSFSES
                     FFNLFTMQFWGIVLVIIFVAKMLTKEN"
     gene            complement(5898..6884)
                     /locus_tag="VQ865_000297"
     CDS             complement(5898..6884)
                     /locus_tag="VQ865_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3134720.1"
                     /translation="METALISVIVPVYNVAQYLEKSIASIQKQTYQNLEIILVDDGAT
                     DESGRLCDSIAEQDDRVSVLHKKNEGLSQARNDGMKQAHGDYLIFIDSDDYIHPEMIQ
                     SLYEQLVQEDADVSSCGVMNVYANDESPQSANQDDYFVCDSQTFLKEYLIGEKIPGTI
                     CNKLIKRQIATALSFPKGLIYEDAYYHFDLIKLAKKYVVNTKPYYYYFHRGDSITTKP
                     YAKKDLAYIDIYQKFYNEVVKNYPDLKEVAFFRLAYAHFFILDKMLLDDQYKQFEAYS
                     QIHRFLKGYAFAISRNPIFRKGRRISALALFINISLYRFLLLKNIEKSKKLH"
     gene            complement(6886..7989)
                     /locus_tag="VQ865_000298"
     CDS             complement(6886..7989)
                     /locus_tag="VQ865_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HET3134721.1"
                     /translation="MVAKKKILFFMWSFSLGGGAEKILSTIVSNLDPEKYDIDILEME
                     HFDKGYESVPKHVRILKSLQDYRQTRWLRAFLWRMRIYFPRLTRRLLVKDDYDVEVSF
                     TIMNPPLLFSKRREVKKISWIHGSIEELLKDSSKRESHRSQLDAANTIVGISKKTSNS
                     IKEVYPDYASKLQTIYNGYDFQTILEKSQEKIDIEIAPQSICTIGRIEENKGSDRVVE
                     VIRLLHQEGKNYHLYFIGAGDMEEELKKRVKEYEIEDYVHFLGYQKNPYQYLSQTKVL
                     LSMSKQEGFPGVYVEALSLGLPFISTDVGGAEELSQEGRFGQIIESNQEAAQAITNYM
                     TSASNFNVDEASQFIQQFTITKQIEQVEKLLEE"
     gene            complement(7979..8824)
                     /locus_tag="VQ865_000299"
     CDS             complement(7979..8824)
                     /locus_tag="VQ865_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine transferase LicD"
                     /protein_id="HET3134722.1"
                     /translation="MNNMTDLKAIQARSLEMAEYFVAFCKEHDLLCYLCGGGAIGALR
                     NKGFIPWDDDLDFFMPRKDYEKLAELWPRYADERYFLSKSHKDFVDRNLFITIRDKET
                     TCIKPYQQDLDLPHGLALDVLPLDYYPKNPAERKKQVRWALIYSLFCAQTIPEKHGAL
                     MKWGSRILLGLTPKSLRYRIWKKAEKEMTKYDLADCDGITELCSGPGYMRNKYPITSF
                     EDNLFLPFEGTEMPIPIGYDVYLRTAFGDYMTPPPADKKVPHHDAVIADMDKSYTEYK
                     GEYGG"
     gene            complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ865_000300"
     CDS             complement(9103..10377)
                     /gene="psr"
                     /locus_tag="VQ865_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyisoprenyl-teichoic acid--peptidoglycan
                     teichoic acid transferase Psr"
                     /protein_id="HET3134723.1"
                     /translation="MSKENPLSHHEQLRYDYLLKNIHYLNEREKNEFAYLQEKLTLAR
                     GNSSSSLEQEREEQVDLPSYANRSRSQSKSQALSFPPKKKRRKLRLKRIFMVIFSLLV
                     CVALAMVFMFLRGYQDASAKKTADARAAQVEVFNGQDTRDGVNILIMGTDGRIGQNSV
                     ETRTDSIMVLNVGGSDKKMKLVSFMRDNLVYIDGYSQVINGRKQTDNKLNVAYELGEQ
                     EGQKGAEMVRQVLKDNFDLDIKYYALVDFQAFATAIDTLFPDGVTIDAQFSTLNGRPL
                     TEATVGDDLYATETESPTQTIKVGKQQMNGSTLLNYARFRDDDEADYGRTKRQQQVLT
                     AILEQIKDPTKLFTGSEALGKVFAMTSTNVPYTFLLTNGLSVLDGAKNGIEKLTIPEL
                     GDWVDAYDVYGGLGLLVDQNKYQTKLAQMGLR"
     gene            complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ865_000301"
     CDS             complement(10374..11222)
                     /gene="pheA"
                     /locus_tag="VQ865_000301"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HET3134724.1"
                     /translation="MKIAYLGPKGSFSHHVVQIAFPHEELQAFANITDVIKAYEQGLV
                     DYSVVPVENSIEGSVHETLDYLFHQAHIQAVAEIVQPIHQQLMVVPGHTKIEKIFSHP
                     QALAQGKKFIDEQYPEAQIEVTASTAYAARFISEHPDQPFAAVAPRSSAEEYGLELIA
                     EDIQEMEANFTRFWVLGAEKPSIPLQAQTEKMSLALTLPDNLPGALYKALSTFAWRGI
                     DLTKIESRPLKTALGEYFFIIDVDYTDKDLVHFAQKELEAIGIQYKILGAYPIYPISD
                     HGKERR"
     gene            complement(11219..11695)
                     /locus_tag="VQ865_000302"
     CDS             complement(11219..11695)
                     /locus_tag="VQ865_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HET3134725.1"
                     /translation="MAKVLLGFMGAGKSTIARGLDPNYLDMDALIEKRLGMSIANFFA
                     EKGEAAFRQVESEVLADLLQTDQVVSTGGGVVISQRNRDLLKTNTDNIYLKADFETLY
                     QRIAADKDNQRPLFLNNSKEELVAIFQERQAWYEEVASRVLDVTKLSPEEIIEELR"
     gene            complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ865_000303"
     CDS             complement(11688..12971)
                     /gene="aroA"
                     /locus_tag="VQ865_000303"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004236106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HET3134726.1"
                     /translation="MKLKTNIRHLHGSIRVPGDKSISHRSIIFGSLAEGETKVYDILR
                     GEDVLSTMQVFRDLGVEIEDKDGVITIQGVGMAGLKAPQNALNMGNSGTSIRLISGVL
                     AGADFEVEMFGDDSLSKRPMDRVTLPLKKMGVSISGQTERDLPPLRLKGTKNLRPIHY
                     ELPIASAQVKSALMFAALQAKGESVIIEKECTRNHTEDMLKQFGGHLSVDGKKITVQG
                     PQKLTGQKVVVPGDISSAAFWLVAGLIVPNSRLVLQNVGINETRTGIIDVIRAMGGKL
                     EITEIDPVAKSSTLTVESSDLKGTEIGGALIPRLIDELPIIALLATQAQGVTVIKDAE
                     ELKVKETDRIQVVADALNSMGADITPTADGMIIKGKSALHGARVNTFGDHRIGMMTAI
                     AALLVADGEVELDRAEAINTSYPSFFDDLESLIHG"
     gene            complement(13063..13401)
                     /locus_tag="VQ865_000304"
     CDS             complement(13063..13401)
                     /locus_tag="VQ865_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF/YmcA family competence regulator"
                     /protein_id="HET3134727.1"
                     /translation="MSNIYDSANELSRGLRGLPEYKAVKAAKDAIAADAEASKIFTEY
                     LAFQEEIQKLAHTGQMPDASFQAKMEGFGKQIQGNSLLSEFFTKQQQLAIYLSDIEKI
                     VFEPVSELLK"
     gene            complement(13412..14515)
                     /locus_tag="VQ865_000305"
     CDS             complement(13412..14515)
                     /locus_tag="VQ865_000305"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HET3134728.1"
                     /translation="MAKTIYIAGLGLIGASMALGIKRDHPDYEILGYNRSQASRDIAL
                     KEGMIDRATDDFASFAPLADVIILSLPIKQTIAFIKELANLDLREGVIISDAGSTKST
                     IVDAAEQYLAGKSVRFVGAHPMAGSHKTGAASADVNLFENAYYIFTPSSLTSQDTLKE
                     MKDLLSGLHARFIEIDAKEHDRVTSQISHFPHILASSLMEQTAVYAQEHEMARRFAAG
                     GFRDMTRIAESEPGMWTSILLSNSETILDRIEDFKERLEVIGQAISKGDEEQIWNFFN
                     QAREQRQTMEIHKRGGVDSSYDLYVDVPDEEDVILRILELLRGTSLVNIHINEENRED
                     IHGILQISFKNAQDLERAEHLITENTDYTVVIK"
     gene            complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ865_000306"
     CDS             complement(14525..15691)
                     /gene="aroC"
                     /locus_tag="VQ865_000306"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HET3134729.1"
                     /translation="MRYLTAGESHGPRLTAIIEGIPAGLPLTAEDINEDLRRRQGGYG
                     RGGRMKIESDQVVFTSGVRHGKTTGAPITMDVINKDHQKWLDIMSAEDIEDRLKSKRK
                     ITHPRPGHADLVGGIKYRFDDLRNSLERSSARETTMRVAVGAVAKRLLAELDMEIANH
                     VVVFGGKEIDVPENLTVAEIKQRAAQSEVSIVNQEREQEIKDYIDQIKRDGDTIGGVV
                     ETVVGGVPVGLGSYVQWDRKLDARLAQAVVSINAFKGVEFGLGFEAGYRKGSQVMDEI
                     LWSKEDGYTRRTNNLGGFEGGMTNGQPIVVRGVMKPIPTLYKPLMSVDIETHEPYKAT
                     VERSDPTALPAAGMVMEAVVATVLAQEILEKFSSDNLEELKEAVAKHRDYTKNY"
     gene            complement(15701..16768)
                     /locus_tag="VQ865_000307"
     CDS             complement(15701..16768)
                     /locus_tag="VQ865_000307"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HET3134730.1"
                     /translation="MKIRIDIPHHPYDIQIEKGCMAQAGQWLRELWQPQKVVIVTDNH
                     VASLYAEKVKLSLEDAGFQVAVFDFLEGEERKNLTTVQKVYEFLVKQGLTRSDGIVAL
                     GGGVVGDLAGFVASTYMRGIHFVQIPTSLTAQVDSSIGGKTGVNTPFAKNMVGTFAQP
                     DGVLIDPLVLETLGKRELIEGMGEVIKYGLIEDPELWALLTGLNGSVESILEHAETLI
                     EHSCQVKRKMVVEDELDNGIRLYLNFGHTIGHAIEATAGYGKVMHGEAVAMGMVQISK
                     VAEEKGLMPAGITQSITEMCQKFGLPVDYENWEVDKLYQALTHDKKARGNTLKLVLVP
                     ELGSAIIHPVSLEEMKDYLVK"
     gene            complement(16787..17641)
                     /locus_tag="VQ865_000308"
     CDS             complement(16787..17641)
                     /locus_tag="VQ865_000308"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HET3134731.1"
                     /translation="MKLDGYTRLAAVVANPIKHSISPFIHNRAFEATDTNGAYVAWEI
                     EASDLVETVANIRRYQMFGINLSMPYKEQVIPYLDKLSDEARLIGAVNTVVNENGNLI
                     GYNTDGKGFFKCLPSFTISGKKMTLLGAGGAAKSILAQAILDGVSQISVFVRSVSMEK
                     TRPYLDKLQEQTGFKVDLCALEYVSELQARIAESDLLVNATSVGMDGQSSPVPENIVL
                     PETLLVADIIYQPFETPFLKWARSQGNPAVNGLGMLLYQAAEAFQLWTGKEMPTEEIW
                     QSLTEKYQ"
     gene            complement(17631..18308)
                     /locus_tag="VQ865_000309"
     CDS             complement(17631..18308)
                     /locus_tag="VQ865_000309"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HET3134732.1"
                     /translation="MKLIVSVMPRSLEEAQALDDTRYLDADIIEWRADYLPKEAILQV
                     APAIFEKFAGRELVFTLRTRSEGGEIDLSPEEYIHLIKEVAQLYQPDYIDFEYYSYKD
                     VFEEMLDFPNLVLSYHNFQETPENMMEILSELTILNPKLVKVAVMAHTEQDVLDLMNY
                     TRGFKTLNPEQEYVTISMGKVGKVSRITADVTGSSWSFASLDEVSAPGQISLASMKKI
                     REILDEA"
     gene            complement(18305..19468)
                     /locus_tag="VQ865_000310"
     CDS             complement(18305..19468)
                     /locus_tag="VQ865_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HET3134733.1"
                     /translation="MNRIRVSKRVEKKLAKGLVLLEASDLENVNLKDQEVEVQGQEGN
                     FLGTAYLSQQNKGLGWFVSKDKVAFNQTFFETLFRKAKEKRNAYYQDDLTTAFRLFNQ
                     EGDGFGGLTVDLYGDYAVFSWYNSYVYQIRQTISEAFRQVFPEVLGAYEKIRFKGLDY
                     ESAHVYGQEAPDFFTVLENGVLYQVFMNDGLMTGIFLDQHEVRGSLVDGLAMGKSLLN
                     MFSYTAAFSVAAAMGGASQTTSVDLAKRSRELSQAHFQANGLSTDEHHFIVMDVFEYF
                     KYAKRKDLTYDVIVLDPPSFARNKKQTFSVAKDYHKLISQSLEILNPGGIIIASTNAA
                     NVSRQKFTEQIDKGFAGRSYQILNKYGLPADFAYNKKDESSNYLKVISMKVSK"
     gene            complement(20155..21789)
                     /locus_tag="VQ865_000311"
     CDS             complement(20155..21789)
                     /locus_tag="VQ865_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134734.1"
                     /translation="MRLKVIKKLVDINILYSSQDANLANPRKKQAKNTGKKVNVSARV
                     LSSYIFSSLLMLIFFSTIAIHFPFEEMPVYFSFMVAILLVIAFSTSLTAFYNVFYESK
                     DLASYSPYAFKESEIIIAKGLSVLLPALTGIVPILAYFLALYISLAPSLWLGLPLMLL
                     SLTLLFVSVTLVTVVAVHFLAQTRVFRKYQSIFSNVMIGIGVLIPLIFIFFLQSTFGS
                     IVDKVRDIPFLLYPLHIFYKIAVEPFSIEAILGLLAWIGLTLFLLYLTKKKVLPRFYD
                     VILLNSEEKVKKERRSKERISTTKKGFFRMVLRYHLTLLGQGTGVVTVLFTSAFLPYL
                     MMIGLISKIRDSQIVPDIHPPYWLPLFFIALFIAVVNNNITSLPSIALSLERENVDFL
                     KSLPFDFARYVKVKFWIIFAVQSFLPILTLLGLSLYLGLPIISMIYLIVAWILASVIL
                     SCHHYFKDVKNLSTNWSSITDLVNRSNGIVAIVLLFIYSAILMALVIGSIFLVQSLSP
                     ILAISLGVGALILLLALAIFGYHYYLSRILAEIEKR"
     gene            complement(21770..22519)
                     /locus_tag="VQ865_000312"
     CDS             complement(21770..22519)
                     /locus_tag="VQ865_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134735.1"
                     /translation="MIEFQNVSKLYGDKEALSNLNLQIENGEIMGLIGHNGAGKSTTI
                     KSLVSIISPSSGRILVDGQELSENRLAIKRKIGYVADSPDLFLRLTANEFWELIASSY
                     DLSRSDLEASLARLLNVFDFAENRYQVIETLSHGMRQKVFVIGALLSDPDIWVLDEPL
                     TGLDPQAAFDLKQMMKEHAQKGKTVLFSTHVLEVAEQVCDRIAILKKGHLIYCGKVED
                     LRKDNPDQSLESIYLSLAGRKEEVSDASQGH"
     gene            22698..24152
                     /locus_tag="VQ865_000313"
     CDS             22698..24152
                     /locus_tag="VQ865_000313"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HET3134736.1"
                     /translation="MQNQTLMQYFEWYLPHDGQHWTRLAEDAPHLAHLGISHVWMPPA
                     FKATNEKDVGYGVYDLFDLGEFNQKGTVRTKYGFKEDYLQAIQALKAQGIQPMADVVL
                     NHKAAADHMEAFQVIEVDPVDRTVELGEPFTINGWTSFTFYGRQDTYNDFHWHWYHFT
                     GTDYDAKRRKSGIYLIQGDNKGWANEELVDNENGNYDYLMYADLDFKHPEVIQNIYDW
                     ADWFMETTGVAGFRLDAVKHIDSFFMRNFIRDMKEKYGDDFYVFGEFWNPDKEANLDY
                     LEKTEEHFDLVDVRLHQNLFEASQAGANYDLRGIFTDSLVELKPDKSVTFVDNHDTQR
                     GQALESTVEEWFKPAAYALILLRQDGLPCVFYGDYYGISGQYAQQDFKEILDRLLAIR
                     KDLAYGEQNDYFDHANCIGWVRSGAENQSPIAVLISNDQENSKSMFVGQEWTNQTFVD
                     LLGNHQGQVTIDEEGYGQFPVSARSVSVWAVNTI"
     gene            complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ865_000314"
     CDS             complement(24241..26859)
                     /gene="alaS"
                     /locus_tag="VQ865_000314"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HET3134737.1"
                     /translation="MKQLSSAQVRQMWLDFWATKGHSVEPSVSLVPVNDPTLLWINSG
                     VATLKKYFDGTIIPENPRITNAQKAIRTNDIENVGKTARHHTMFEMLGNFSIGDYFRD
                     EAITWAYELLTSPEWFDFPAEKLYMTYYPDDKDSYNRWIEVGVDPSHLIPIEDNFWEI
                     GAGPSGPDTEIFFDRGEAFDPENIGLRLLAEDIENDRYIEIWNIVLSQFNADPAVPRS
                     EYKELPHKNIDTGAGLERLVAVIQGAKTNFETDLFMPIIREVEKLSGKVYDQDGDNMS
                     FKVIADHIRSLSFAIGDGALPGNEGRGYVLRRLLRRASMHGQKLGINEPFLYKLVPTV
                     GKIMESYYPEVLEKRDFIEKIVKSEEESFARTLHSGQHFAQGIVADLKEKGQSVIAGS
                     DVFKLYDTYGFPVELTEEIAEEAGMTVDREGFEAAMKEQQERARASAVKGGSMGMQNE
                     TLQNITVESVFNYNASQLSSKLVAIVADNAEVEAVSEGTASLIFAETSFYAEMGGQVA
                     DYGQILDESGKVVATVTNVQKAPNGQALHTVEVLAPLALNQEYTLVIDSNRRHRVMKN
                     HTATHLLHAALHNILGNHATQAGSLNEVEFLRFDFTHFQAVTAEELRAIEQQVNEKIW
                     EALEVKTVETDIDTAKEMGAMALFGEKYGKEVRVVTIGDYSIELCGGTHVGNTSEIGL
                     FKIVKEEGIGSGTRRILAVTGKEAFEAYREQEDALKAVAATLKAPQVKEVPHKVEGLQ
                     EQLRQLQKENAELKEKAAAAAAGDIFKDAKEVNGHRYIASQVSVSDAGALRTFADNWK
                     QKDYSDLLVLVAAIGDKVNVLVASKTKDLHAGNLVKELAPIIDGRGGGKPDMAMAGGS
                     NQAKIQELLDVVAGKL"
     gene            complement(26881..27366)
                     /locus_tag="VQ865_000315"
     CDS             complement(26881..27366)
                     /locus_tag="VQ865_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LURP-one-related family protein"
                     /protein_id="HET3134738.1"
                     /translation="MKTFLVKQKFRLGGERFAIKDDRGEIAYQVEGSFFKIPKTFTIY
                     DAAGEQVSQISKEILTLLPRFEIQLRDGSSFVIRKKLTFWRDKYEFDNLGLRIEGNIW
                     DLNFKLLDDRDQLIAEIKKELFHLTSTYTVTVLEDAYADLVISLCVAIDYVEMLESQS
                     H"
     gene            complement(27641..27880)
                     /locus_tag="VQ865_000316"
     CDS             complement(27641..27880)
                     /locus_tag="VQ865_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000784186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134739.1"
                     /translation="MKMSTFFKKSFWPTFMIVNQTAILFHLKDGLDRQYLTTESIYWV
                     IGTFIFGNILVAVFSNMKIWDKKKNGSKKKYILKK"
     gene            complement(28141..29211)
                     /locus_tag="VQ865_000317"
     CDS             complement(28141..29211)
                     /locus_tag="VQ865_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3134740.1"
                     /translation="MKKIYSFLAGIAAIILVLWGIATHLDSKINSRDSQKLVIYNWGD
                     YIDPELLTQFTEETGIQVQYETFDSNEAMYTKIKQGGTTYDIAIPSEYMINKMKDEDL
                     LVPLDYSKIKGIENIGPEFLNQSFDPGNKFSIPYFWGTLGIVYNETMVDEAPEHWDDL
                     WKPEYKNSIMLFDGAREVLGLGLNSLGYSLNSKDLQQLEETVDKLYKLTPNIKAIVAD
                     EMKGYMIQNNVAIGVTFSGEASQMLEKNENLRYVVPTEASNLWFDNMVIPKTVKNQNS
                     AYAFINFMLKPENALQNAEYVGYSTPNLPAKELLPEETKEDKAFYPDVETMKHLEVYE
                     KFDHKWTGKYSDLFLQFKMYRK"
     gene            complement(29208..29981)
                     /locus_tag="VQ865_000318"
     CDS             complement(29208..29981)
                     /locus_tag="VQ865_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3134741.1"
                     /translation="MKKFANLYLGLVFLVLYLPIFYLIGYAFNAGDDMNSFTGFSWTH
                     FETMFGDGRLMLILAQTFFLAFLSALIATIIGTFGAIYIYQSRKKYQEAFLSLNNILM
                     VAPDVMIGASFLILFTQLKFSLGFLTVLSSHVAFSIPIVVLMVLPRLKEMNGDMIHAA
                     YDLGASQFQMFKEIMLPYLTPSIIAGYFMAFTYSLDDFAVTFFVTGNGFSTLSVEIYS
                     RARKGISLEINALSALVFLFSIILVVGYYFISREKEEQA"
     gene            complement(29978..30784)
                     /locus_tag="VQ865_000319"
     CDS             complement(29978..30784)
                     /locus_tag="VQ865_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3134742.1"
                     /translation="MKKTSSKLFVVPYMLWIALFVLAPLVLIFGQSFFNIEGQFSLEN
                     YKSYFASQNLTYLKMSFNSVLYAGIVTFVTLLISYPTALFLTRLKHRQLWLMLIILPT
                     WINLLLKAYAFIGIFGQNGSINQFLEFIGIGSQQLLFTDFSFIFVASYIELPFMILPI
                     FNVLDDMDNNLINASYDLGATKWETFRHVIFPLSMNGVRSGVQSVFIPSLSLFMLTRL
                     IGGNRVITLGTAIEQNFLTNDNYGMGSTIGVILILTMFITMWVTKERRER"
     gene            complement(30765..31922)
                     /locus_tag="VQ865_000320"
     CDS             complement(30765..31922)
                     /locus_tag="VQ865_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018372333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134743.1"
                     /translation="MKKPIIEFKNVSKVFEDSNTKVLKDINFELEEGKFYTLLGASGS
                     GKSTILNIIAGLLDATTGDIMLDGVRINDIPTNKRDVHTVFQSYALFPHMNVFENVAF
                     PLRLRKIDKKEIEQRVAEVLKMVQLEGYEKRSIRKLSGGQRQRVAIARAIINQPRVVL
                     LDEPLSALDLKLRTDMQYELRELQQRLGITFVFVTHDQEEALAMSDWIFVMNDGEIVQ
                     SGTPVDIYDEPINHFVATFIGESNILPGTMIEDYLVEFNGKRFEAVDGGMKPNEPVEV
                     VIRPEDLRITLPEEGKLQVKVDTQLFRGVHYEIIAYDELGNEWMIHSTRKAIVGEEIG
                     LDFESEDIHIMRLNETEEEFDARIEEYVEIEEQEAGLINAIEEERDEENKL"
     gene            complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ865_000321"
     CDS             complement(32082..32987)
                     /gene="murB"
                     /locus_tag="VQ865_000321"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000116193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HET3134744.1"
                     /translation="MSVREKMLEILEGIDIRFKEPLHSYSYTKVGGEADYLVFPRNRF
                     ELARLVKFANQENIPWMVLGNASNIIVRDGGIRGFVILCDKLNNVSVDGYTIEAEAGA
                     NLIETTRIALRHSLTGFEFACGIPGSVGGAVFMNAGAYGGEIAHILQSCKVLTKDGEI
                     ETLSAKDLAFGYRHSAIQESGAVVLSVKFALAPGTHQVIKQKMDRLTHLRELKQPLEY
                     PSCGSVFKRPVGHFAGQLISEAGLKGYRIGGVEVSEKHAGFMINVADGTAKDYEDLIQ
                     SVIEKVKEHSGITLEREVRILGESK"
     gene            complement(33099..33851)
                     /locus_tag="VQ865_000322"
     CDS             complement(33099..33851)
                     /locus_tag="VQ865_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfC family intramembrane metalloprotease"
                     /protein_id="HET3134745.1"
                     /translation="MTIHIIITMLLLLAFLIGSIWFTKKKYQINLAVLGLGAVAFFVS
                     SQILEKLVHILILHPQKDGSIALLQDHPLIYIIYGLAMAAFFEETARLVFFKWLEKKR
                     SLEKADALAYGLGHGGLELIFLGLISLLNLYIVLSAVQTQNPQVMQLLSENMLKTIQS
                     LSVWQIYLLGFERILALGFQLLLTVWVYQAVRQKKWIYLLAAYGLHAFFDLAPSLFQV
                     GWLTNPVLVEVILALELVLVAYGTKEIFCKKS"
     gene            complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ865_000323"
     CDS             complement(33861..34592)
                     /gene="budA"
                     /locus_tag="VQ865_000323"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HET3134746.1"
                     /translation="MDKNVQEPVKLFQYNTLGALMAGLYGGTMTVGELLEHGDLGLGT
                     LDSIDGELIVLDGKAYQAKESGDQPEIVEVSPDALIPYAAVVPHQAEVIFRQRFEMTD
                     KELKERIESYYDGENLFRSIKIRGEFSHMHVRMIPKSTPDTKFADIATHQPEYSRDNV
                     AGTIVGFWTPQIFHGVSVAGYHLHFISDDLTFGGHVMDFVIKEGIIEVGAVDQLDQRF
                     PVQDRQYLFAKFNVDEMKKDIEKAE"
     gene            34734..36005
                     /locus_tag="VQ865_000324"
     CDS             34734..36005
                     /locus_tag="VQ865_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HET3134747.1"
                     /translation="MKKQSKYKEVVSYLKNGIESGRFPTGSRLPSIRQLSLDFHCSKD
                     TIQRALLELRHEQYLYAKPQSGYYVLEQGQHQDLEIEVTDEHASAYDDFRLCVNETLI
                     GRENYLFNYYDNQEGLEDLRQSIHKLLFDQALYCKANQLVLTSGTQQALFILSQISFP
                     SQAKEILVEQPTYHRMNRLLIAQGLDYQTIERGIDGIDLEELEGHFKTGKIKFFYTIP
                     RFHYPLGHSYSEQDKRAILDLAAKYSVYIVEDDYLGDLDSKKGQTFHYLDTEERVIYI
                     KSFSTSLFPALRITALILPNTIKEAFVAYKNILDYDSNLIMQKALSLYIDSQLFEKNR
                     LARLTNHESYQKQIEERITKTPCPLPHYPLHDGLLLDLRQYPKIASLKHSQLGLDFFE
                     EAYLSTCPYQFAKVSLDNLENVLNYLKAELE"
     gene            complement(36025..36840)
                     /locus_tag="VQ865_000325"
     CDS             complement(36025..36840)
                     /locus_tag="VQ865_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3134748.1"
                     /translation="MKSKKWIFVLCNFLASFFLVACQSGSNGSQSAVEAIKQKGKLVV
                     ATSPDYAPFEFQSLVDGKNQVVGADIDMAQAIADELGVKLEILSMSFDNVLTSLQTGK
                     ADLAVAGISATDERKEVFDFSIPYYENKISFLVRKADVEKYKDLTSLESANIAAQKGT
                     VPESMVKEQLPKAQLTSLTNMGEAVNELQAGKIDAVHMDEPVALSYAAKNAGLAVATV
                     SLKMKDGDANVVALRKNSDDLKEVVDKVIQKLKDEGTYQSYLEKAASLTEVEE"
     gene            complement(36997..37650)
                     /gene="phoU"
                     /locus_tag="VQ865_000326"
     CDS             complement(36997..37650)
                     /gene="phoU"
                     /locus_tag="VQ865_000326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000946475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3134749.1"
                     /translation="MLRSQFEEDLEKLHNQFYAMGQEVLSQINRTVRAFVTHDRDLAK
                     EVIEDDAEVNEYEVKLEKKSFEMIALQQPVSQDLRTVLTVLKAVSDVERMGDHAVAIA
                     QATIRMKGEERIPAVEEEIKKMGREVKSVVEAALDLYLNGSVDDAYRVASMDEQINHY
                     FETIRDLATEEIKKNPEAIVTGRDYFQVISYLERIGDYAKNICEWVVYFETGKIVEL"
     gene            complement(37662..38420)
                     /gene="pstB"
                     /locus_tag="VQ865_000327"
     CDS             complement(37662..38420)
                     /gene="pstB"
                     /locus_tag="VQ865_000327"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3134750.1"
                     /translation="MTDAILQVSDLSVYYNKKKALNSVSLSFQPKEITALIGPSGSGK
                     STLLKSLNRMGDLNPEVTTTGSVVYNGHNIYSPRTDTVELRKEIGMVFQQPNPFPMTI
                     YENVVYGLRINGIKDKQVLDEAVEKALQGASIWDEVKDRLYDSAIGLSGGQQQRVCVA
                     RVLATSPKIILLDEPTSALDPISAGKIEETLYGLKDKYTMLLVTRSMQQASRISDKTG
                     FFLDGDLIEFNDTKQMFLDPQHKETEDYITGKFG"
     gene            complement(38433..39236)
                     /gene="pstB"
                     /locus_tag="VQ865_000328"
     CDS             complement(38433..39236)
                     /gene="pstB"
                     /locus_tag="VQ865_000328"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3134751.1"
                     /translation="MSTYNWDEKHILTFPEEKVALSTKDVHVYYGKNESIKGIDMQFE
                     RNKITALIGPSGSGKSTYLRSLNRMNDTIDIAKVTGQILYRGIDVNRPEINVYEMRKH
                     IGMVFQRPNPFAKSIYRNITFAHERAGVKDKQVLDEIVETSLRQAALWDQVKDDLHKS
                     ALTLSGGQQQRLCIARAISVKPDILLMDEPASALDPIATMQLEETMFELKKNFTIIIV
                     THNMQQAARASDYTGFFYLGDLIEYDKTATIFQNAKLQSTNDYVSGHFG"
     gene            complement(39247..40131)
                     /gene="pstA"
                     /locus_tag="VQ865_000329"
     CDS             complement(39247..40131)
                     /gene="pstA"
                     /locus_tag="VQ865_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009443446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3134752.1"
                     /translation="MRAKKLDKLATAVLYTIASIIVTILASLILYILVRGLPHISWSF
                     LTGRSSAFQAGGGIGIQLYNSFFLLVITLIISVPLSMGAGIYLAEYAKKGPVTNFVRT
                     CIEILSSLPSVVVGLFGYLIFVVQFEYGFSIISGALALTVFNLPQMTRNVEDSLKHVH
                     HTQREAGLALGISRWETVVHVVIPEALPGIVTGVVLASGRIFGEAAALIYTAGQSAPA
                     LDWSNWNILSVTSPISIFRQAETLAVHIWKVNSEGTIPDGTIVSAGSAAVLLIFILIF
                     NFGARKFGSYLHKKLTAA"
     gene            complement(40121..41038)
                     /gene="pstC"
                     /locus_tag="VQ865_000330"
     CDS             complement(40121..41038)
                     /gene="pstC"
                     /locus_tag="VQ865_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018378778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3134753.1"
                     /translation="MNQEELAKKMLLPSKNSRLEKLGKGLTFACLSLIVILVAMILVF
                     VAQKGLSTFFVNGVNIFDFLLGGTWNPSSKEFGALPMILGSFIVTILSALIATPFAIG
                     AAVFMTEVSPKGAKILQPAIELLVGIPSVVYGFIGLQVVVPFVRSVFGGTGFGILSGI
                     SVLFVMILPTVTFMTTDSLRAVPRYYREASFAMGATRWQTIWRVILKAARSGIFTAVV
                     FGMARAFGEALAIQMVVGNSAVIPTSLTTPAATLTSILTMGIGNTVMGTVNNNVLWSL
                     ALVLLLMSLVFNSVIKLITKERGKKNYAR"
     gene            complement(41038..41916)
                     /gene="pstS"
                     /locus_tag="VQ865_000331"
     CDS             complement(41038..41916)
                     /gene="pstS"
                     /locus_tag="VQ865_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HET3134754.1"
                     /translation="MKKRKKLALSLIAFWLTACLVGCASWIDRGESITAVGSTALQPL
                     VEVAADEFGTIHVGKTVNVQGGGSGTGLSQVQSGAVDIGNSDVFAEEKDGIDASALVD
                     HKVAVAGLALIVNKEVDVDNLTTEQLRQIFIGEVTNWKEVGGKDLPISVINRAAGSGS
                     RATFDTVIMEGQSAMQSQEQDSNGAVKSIVSKSPGAISYLSLTYIDDSVKSMKLNGYD
                     LSPENISSNNWPLWSYEHMYTLGQPNELAAEFLNFVLSDETQEGIVKGLKYIPIKEMK
                     VEKDAAGTVTVLEGRQ"
     gene            complement(42490..43794)
                     /locus_tag="VQ865_000332"
     CDS             complement(42490..43794)
                     /locus_tag="VQ865_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmF rRNA methyltransferase first C-terminal
                     domain-containing protein"
                     /protein_id="HET3134755.1"
                     /translation="MKFPEGFVEKYKEILGDEARDFLASFEEEAVSAFRVNPLKEEQL
                     SFSDAITQTPWGHYGKVSGKSPEHATGLVYSQEPAAQMVAQVAQPSPGMKVLDLAAAP
                     GGKSTQLAAYLAGEGLLVSNEISSKRAKILVENMERFGATNVVVTNESADRLVKVFKG
                     YFDLIVLDAPCSGEGMFRKQPDAMDYWSLDYPSQCASLQREILEDAVTMLAEGGRLVY
                     STCTWAPEENEEIVNWLLEEYDFDLLPVEHINGMVAGIDLPETARMYPHQFKGEGQFV
                     AHLQFKGNNPAPKFKASKSNLSREQVALWQEFAQNHLKVNLPGILQIFGDQLYLLPEL
                     LPDLGKLKIARNGLHLGTFKKKRFEPSFALGLALKPSQVEQSVEIGQEEFVKYAAGET
                     VQLAESLPNGWYQVLVKGNGLGFAKVTGNVLKNYFPKGLRFK"
     gene            complement(43795..44568)
                     /locus_tag="VQ865_000333"
     CDS             complement(43795..44568)
                     /locus_tag="VQ865_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HET3134756.1"
                     /translation="MESKFEFAKELVKKAGQYILDHMQEDLRVETKSSPTDLVTRLDK
                     EVQELLVGEILSRYPEDKICAEEGCLRASVQEGKVWVIDPIDGTNNFVAQQEDFAVMM
                     AYFENGQGQFGLIYDVVKGDCYHGGGEFPVCLNDRPLASFKTKPLGDFLIAGNSGMLE
                     TNEWGLADLSRAVLGVRVYGSAAISFAKILSGRLLTYLTYLQPWDYAAASILGESLGY
                     RVVTLFGEAPDFQTRQPVMMVPLEMQEEIQSYIYERKRT"
     gene            complement(44558..44836)
                     /locus_tag="VQ865_000334"
     CDS             complement(44558..44836)
                     /locus_tag="VQ865_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HET3134757.1"
                     /translation="MNKQYSYPLDLSWSTEELASVLSFFNDVEAAYEGKVEAKKLLDS
                     YKGFKAVVPSKSEEKRLGREFETVSGYSLYRAVQAAKEKGEGKISLGK"
     gene            complement(44836..45237)
                     /locus_tag="VQ865_000335"
     CDS             complement(44836..45237)
                     /locus_tag="VQ865_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007556665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HET3134758.1"
                     /translation="MITLFLSPSCTSCRKAKAWLEKHKVPFVEHNIMTSPLTRKELQQ
                     ILSLTENGTDDIISTRSKIFQKLNIDVESISVSELLHLIEQYPSLLRRPIIIDAKRMQ
                     IGFNEDEIRAFLPRSYRKQELKEARMRAGIS"
     gene            complement(45447..46064)
                     /locus_tag="VQ865_000336"
     CDS             complement(45447..46064)
                     /locus_tag="VQ865_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HET3134759.1"
                     /translation="MKTKLTFWGSMLFLLSLSILLTIYLAWIFYPMEIQWLNLTNRVY
                     LKPETIQYNFHILMNYLTNPFSQVLQMPDFRSSAAGLHHFAVVKNLFHLVQLVALVTL
                     PSFYVFVNRIVKKDFLSLYRKSLLTLVVLPVMIGLGGVLIGFDQFFTLFHQILFVGDD
                     TWLFDPAKDPVIMILPETFFLHAFLLFFALYESFFGYLCLKSRRK"
     gene            complement(46054..46827)
                     /locus_tag="VQ865_000337"
     CDS             complement(46054..46827)
                     /locus_tag="VQ865_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HET3134760.1"
                     /translation="MKYKGYLIDLDGTIYKGKDRIPAGETFVHELQKRDIPYLFVTNN
                     TTRTPESVKEMLAQNFNIDTPLSTVYTATLATIDYMNDLGLEKTVYVVGEAGLKEAIK
                     AAGYVEDKENPAYVVVGLDWQVDYEKFATATLAIQKGAHFIGTNPDLNIPTERGLLPG
                     AGSLITLLEVATRVKPVYIGKPNAIIMDKAVEHLGLEREELIMVGDNYLTDIRAGIDN
                     GIPTLLVTTGFTKAEEVAGLPIAPTHVVSSLAEWDFDEN"
     gene            complement(46838..47575)
                     /locus_tag="VQ865_000338"
     CDS             complement(46838..47575)
                     /locus_tag="VQ865_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000524807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HET3134761.1"
                     /translation="MGLTYQMKMKIPFDMADMNGHIKLPDVILLSLQVSGMQSIELGV
                     SDKAILEDYNLVWIIAEYDIEVVRLPRFAEEITIETEALSYNRLFCYRRFTIYNEAGQ
                     ELIHMMATFVLMDRDSRKVHVVEPEIVAPYQSDFDKKLIRGPKYESLEEPISKDYHVR
                     FYDLDMNGHVNNSKYLDWIFEVMGADFLTHYIPKKINLKYVKEVRPGGVITSAVERTG
                     LESKHEITSDGVINAQAIITWQEIKKA"
     gene            complement(47580..48710)
                     /locus_tag="VQ865_000339"
     CDS             complement(47580..48710)
                     /locus_tag="VQ865_000339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HET3134762.1"
                     /translation="MQKKPTSAYVHIPFCTQICYYCDFSKVFIKNQPVDSYLEHLLEE
                     FRSYDIEKLSTLYIGGGTPTALSAPQLEVLLNGLTKNLDLSVLEELTIEANPGDLDAD
                     KIAVLKNSAVNRVSLGVQTFDDKMLKKIGRSHLEKDIYENIDRLKLAGFDNISIDLIY
                     ALPGQTMEQVKENVAKAIGLDIPHMSLYSLILENHTVFMNRMRRGKLPLPKEELEAEM
                     FEYIIAELERAGFEHYEISNFSKPGFESRHNLMYWDNAEYYGIGAGASGYVNGVRYKN
                     YGPIRHYLSAVEEGNACITEDHLSQKEQMEEEMFLGLRKKSGVSMARFEEKFGQSFAG
                     LYGEIVRDLVQQGLMQIEGDHVRMTKRGLFLGDTVAERFILE"
     gene            complement(48794..49183)
                     /locus_tag="VQ865_000340"
     CDS             complement(48794..49183)
                     /locus_tag="VQ865_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3134763.1"
                     /translation="MGKLSSILLGTVSGAALALFLTSDKGKQVCSQAQDFLDDLREDP
                     EYAKEQVCEKLTEVKEQATDFVLKTKEQVESGEITVDSILAQAKSYAFQATEASKNQL
                     NNLKEQWQEKAEALDDSEEIVIDITEE"
     gene            complement(49199..49582)
                     /locus_tag="VQ865_000341"
     CDS             complement(49199..49582)
                     /locus_tag="VQ865_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HET3134764.1"
                     /translation="MLEVAYILVALALIVFLVYLIITVQKLGRVIDETEKTIKTLTSD
                     VDVTLHHTNELLAKVNVLADDINVKVATIDPLFSAVADLSLSVSDLNDHARVLSKKAS
                     SAGSKTLKTGASLSALRLASKFFKK"
     gene            complement(49583..50371)
                     /locus_tag="VQ865_000342"
     CDS             complement(49583..50371)
                     /locus_tag="VQ865_000342"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HET3134765.1"
                     /translation="MLDPIAIQLGPLAIRWYALCIVTGLILAVYLTMKEAPRKKIIPD
                     DILDFILVAFPLAILGARLYYVIFRFDYYSQNLGEIFAIWNGGLAIYGGLITGALVLY
                     IFADRKLINTWDFLDIAAPSVMIAQSLGRWGNFFNQEAYGATVDNLDYLPGFIRDQMY
                     IEGSYRQPTFLYESLWNLLGFALILIFRRKWKSLRRGHITAFYLIWYGFGRMVIEGMR
                     TDSLMFFGLRVSQWLSVVLIGLGIMIVIYQNRKKAPYYITEEEN"
     gene            complement(50364..51299)
                     /locus_tag="VQ865_000343"
     CDS             complement(50364..51299)
                     /locus_tag="VQ865_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HET3134766.1"
                     /translation="MSVLVKEVIEKLRLDIVYGEPELLEKEINIADITRPGLEMTGYF
                     DYYTPERIQLLGMKEWSYLISMPSNSRYEVLKKMFLPETPAVIVARGLVVPEEMLKAA
                     RECKIAILTSRAATSRLSGELSSYLDSRLAERTSVHGVLMDIYGMGVLIQGDSGIGKS
                     ETGLELVKRGHRLVADDRVDIFAKDEITLWGEPAEILKHLIEIRGVGIIDVMSLYGAS
                     AVKDSSQVQLAVYLENYDTHKTFDRLGNNAEELEVSGVAIPRIRIPVKTGRNISVVIE
                     AAAMNYRAKEMGFDATRLFDERLTSLIARNEVQNA"
     gene            complement(51429..51605)
                     /locus_tag="VQ865_000344"
     CDS             complement(51429..51605)
                     /locus_tag="VQ865_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HET3134767.1"
                     /translation="MSKTVVRKNESLDDALRRFKRAVTKAGTLQETRKREFYEKPSVK
                     RKRKSEVARKRKKF"
     gene            complement(51745..52452)
                     /locus_tag="VQ865_000345"
     CDS             complement(51745..52452)
                     /locus_tag="VQ865_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HET3134768.1"
                     /translation="MKVIKVENQVQGGKVAFEILKEKLANGAQTLGLATGSSPLEFYK
                     EIVESDLDFSNLTSVNLDEYVGLDGDNPQSYRYFMQENLFNQKPFKESFLPRGVKDNA
                     EAEVERYNQILADHPVDLQILGIGRNGHIGFNEPGTPFDSQTHLVELDQSTIEANARF
                     FAKIEDVPTQAISMGIKNILDAKSIILFAYGESKAEAIAGTVSGPVTENLPASSLQNH
                     PDVTIIADAEALSLLEK"
     gene            52603..53631
                     /gene="queA"
                     /locus_tag="VQ865_000346"
     CDS             52603..53631
                     /gene="queA"
                     /locus_tag="VQ865_000346"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HET3134769.1"
                     /translation="MNTADFDFHLPEELIAQTPLEKRDASKLLIVNRETGEMQDKHFH
                     SIIDMLEPGDALVMNDTRVLPARLYGQKMETGGHVELLLLKNTSGDEWEVLAKPAKRL
                     KVGTRISFGDGRLSAVVTEELTHGGRIVRFEYQGIFLEVLESLGEMPLPPYIHEKLDD
                     RERYQTVYAKESGSAAAPTAGLHFTKELLAEIQAKGVHLVYLTLHVGLGTFRPVSVDN
                     LDEHEMHSEFYQLSEEAAATLRSVKENGGRVIAVGTTSIRTLETIGSKFDGQIQADSG
                     WTNIFIKPGYEWKVVDAFSTNFHLPKSTLVMLVSAFAGRELVLDAYHHAIQEHYRFFS
                     FGDAMFIY"
     gene            complement(54292..54681)
                     /locus_tag="VQ865_000347"
     CDS             complement(54292..54681)
                     /locus_tag="VQ865_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3134770.1"
                     /translation="MVKRRIRRGTREPEKVVVPEQSSIPSYPVSVTSNQGTDVAVEPA
                     KAVAPTTDWKQENGMWYFYNTDGSMATGWVQVNGSWYYLNSNGSMKVNQWFQVGGKWY
                     YVNASGELAVNTSIDGYRVNDNGEWVR"
     gene            complement(54735..55426)
                     /locus_tag="VQ865_000348"
                     /pseudo
     CDS             complement(54735..55426)
                     /locus_tag="VQ865_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846497.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
     gene            complement(56141..56692)
                     /locus_tag="VQ865_000349"
     CDS             complement(56141..56692)
                     /locus_tag="VQ865_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000835652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134771.1"
                     /translation="MKSIGTQILQTERLILRRFVESDAEAMFQNWASSAENLTYVTWD
                     PHPDVEITRNSICNWVASYTNLNYYKWAICLKENPEQVIGDISIVKIDEADLSCEIGY
                     VLGKAYWGNGMMTETLKAILDFCFTQAGFQKVRARYASLNPASGRVMEKAGMSYLQTI
                     VNGVERKGYLADLIYYGISREEC"
     gene            complement(57042..57866)
                     /gene="nadE"
                     /locus_tag="VQ865_000350"
     CDS             complement(57042..57866)
                     /gene="nadE"
                     /locus_tag="VQ865_000350"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HET3134772.1"
                     /translation="MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFV
                     LGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIAVRLPYGVQADEADAQKALAFIQ
                     PDVSLVVNIKESADAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
                     DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDK
                     PGLADEVALGVTYAEIDDYLEGKTISPEAQATIENWWHKGQHKRHLPITVFDDFWE"
     gene            complement(57863..59323)
                     /locus_tag="VQ865_000351"
     CDS             complement(57863..59323)
                     /locus_tag="VQ865_000351"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HET3134773.1"
                     /translation="MYPDDSLTLHTDLYQINMMQVYFDQGIHNKKAVFEVYFRQQPFK
                     NGYAVFAGLERIVNYLEDLRFSDSDIAYLESLGYHGAFLDYLRNFKLELTVRSAQEGD
                     LVFANEPIVQVEGPLAQCQLVETALLNIVNYQTLVATKAARIRSVIEDEPLMEFGTRR
                     AQEMDAAIWGTRAAVIGGANGTSNVRAGKLFDIPVLGTHAHALVQVYGNDYEAFKAYA
                     ATHKNCVFLVDTYDTLRIGVPAAIQVARELGDQINFMGVRIDSGDIAYISKKVRQQLD
                     EAGFTEAKIYASNDLDENTILNLKMQKAKIDVWGVGTKLITAYDQPALGAVYKIVAIE
                     DETGQMRNTIKLSNNAEKVSTPGKKQVWRITSREKGKSEGDYITYDGVDISDMTEIKM
                     FHPTYTYIKKTVRNFDAVPLLVDIFKEGILVYNLPSLTDIQDYARKEFDKLWDEYKRV
                     LNPQHYPVDLARDVWQDKMDLIDKMRKEALGEGEEE"
     gene            complement(59439..59927)
                     /locus_tag="VQ865_000352"
     CDS             complement(59439..59927)
                     /locus_tag="VQ865_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134774.1"
                     /translation="MKNRFYYYQLLDEREEQLFNKAGSESFYICIALSLLSYIISVLA
                     PSLFNSNMLLIVIIIGTFYFFNRARYLGVTYYSRFHFTILGCFFLTLAITALLMLQNY
                     QFNIEIYQHNPLNFKYLSAWVITYIIYLPWIFIGNLGLKSYGEWAQKKFEQDMDELES
                     GE"
     gene            complement(59917..60126)
                     /locus_tag="VQ865_000353"
     CDS             complement(59917..60126)
                     /locus_tag="VQ865_000353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3134775.1"
                     /translation="MAKNLKLKLARVERDLTQGQLAEAVGVTRQTIGLIEAGKYNPSL
                     SLCQSICRCLGKTLDQLFWEEEDEK"
     gene            complement(60512..60992)
                     /locus_tag="VQ865_000354"
                     /pseudo
     CDS             complement(60512..60992)
                     /locus_tag="VQ865_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863700.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(61152..61886)
                     /locus_tag="VQ865_000355"
     CDS             complement(61152..61886)
                     /locus_tag="VQ865_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134776.1"
                     /translation="MRIKEKTNNINGGIKNVSKHYGHSIILKDINFALNKGEIVGLAG
                     RNGVGKSTLMKILVQNNQPTSGNIISSDNVGYLIEEPKLFLSKTGLENLKYLSNLYGV
                     DYNQERFRCLIQELDLTQSINKKVKTYSLGTKQKLALLLTLVTEPDILILDEPTNGLD
                     IESSQIVLAVLKKLALHENVGILISSHKLEDIEEICERVLFLENGLLTFQKVGKDSHN
                     FLFEIAFSSATDRDIFITKQEFWDIV"
     gene            complement(62221..>62379)
                     /locus_tag="VQ865_000356"
     CDS             complement(62221..>62379)
                     /locus_tag="VQ865_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase C-terminal
                     domain-containing protein"
                     /protein_id="HET3134777.1"
                     /translation="AKGNKIDRAPNPMELLTIKVPQPVQAGDMVRALKEGLINLYKED
                     GTSVTVRA"
BASE COUNT        18595 a        14072 c        11470 g        18242 t
ORIGIN      
        1 acaacctcaa aacactgttt tgagcagcct gcggctagct tcctagtttg ctctttgatt
       61 ttcattgagt ataaacttct tttcacaaaa aggatatgaa accctctggt caagagtttc
      121 cccatcctat cttctattct ttattttgct tctacacgga caccttgggt atcaactctc
      181 aagtcatgca gttttccttt gaaaggttgc ttttccaatt ctgccttaat tgttggcatc
      241 ttgtcatgag aagccagaac cataactgtc ggcccagcac cagaaaggta ggttgcatag
      301 gccccatttt ctttggtcac ttgcttaatc atcgcaaatt ctcttaccaa gtcctgacga
      361 tagcgctcat ggaagaggtc tccctcgatt gcttgcccag cggtcaccat gtctcctgcc
      421 aacaaggcag caaccgctac attggcgata gaacttgcag caacagcttc cttataagac
      481 aattttttag gcaagacact acggctgtcg cgagtacgta attcatagtt tggaatgtaa
      541 gctagaaaat cacactctgg aaagtctgct acgatagcag agacttgccc ttcaacagaa
      601 cttgcaataa cgagattacc ataaatggct ggagccacat tgtcaggatg cccttcaatc
      661 ttggtcgcta actgcaattt ttcatggtct gataagttga gttgacccag ttggttggct
      721 agttcaatcc cagcaacgat aaccgagctg gaagaaccca aaccgcgcgc caaagggaca
      781 tcactggtca ttttcaagcg tcttggttgc aagtctggta caatttgcaa agcgattttg
      841 agcaagagat tacgctcatc atgtggaatc catttgccaa tctggtgttc aatcagccac
      901 tcatctcgtt cttcgcagac ctcaatttga agatacttgg ttacagctac accgaccgag
      961 tcaaaacctg gcccgatatt ggcactggtt gcaggtacaa taatcttcat cttattctcc
     1021 tagcaccttg aaggtattca agaggtcgaa ttctgaaacc ttcttcaatt cagctgagac
     1081 attttcaagc tgggctttat taatcttgtg tgtgatgata acgacacgcg ccttgtcacc
     1141 ctctttgcca tcttgaagga tttgcttaaa ggaaatatct tgagcattga agatttcagc
     1201 caacttcaag acctgacctt ttgagtctag agccaagatt gagaaatagt agtttgcttt
     1261 gacatcttca ggatttgcca agaccaagtc acggctatat tcgttgaagt ctttgccaat
     1321 agtaccatca ttcaaacgac gaacgatacg gacaatatca gctacaacac ttgttgcagt
     1381 tggtttttga ccagcacctg gtccgtagta catagactca ccaataccga tagattctac
     1441 aaagacagcg ttcattacgc cattcacact agcaagtggg tgcgctttag gtaggaaggt
     1501 tggagtcact tctgcagcaa tacctgaaga agtttcctca atagaaccaa ccaatttcac
     1561 tacgtaacca agctcttgag ctacagctac gtcttctggt gtgatattgc ggattccctt
     1621 gtgggctaca tcatcaaagg caatcttcat gccaaaggca aattggctca aaataaccat
     1681 cttgtaggct gcatcaatcc catctacgtc attcgtcgga tcgctttctg caaatcctag
     1741 acgttgtgct tccgcaagag catcatcgta agaccagcct tcttccacca tcttggtcac
     1801 catgaagttg gaagttccgt tgactactcc aagcacgcgc gtaattttat cagaagccaa
     1861 ggaatttgct aaagtacgaa gaattggaat cccaccagca actgctgctt cgtagtaaag
     1921 tgctaccttg ttagcttgag cgatttctag caattctgcg ccatggacag ctaaaaggtc
     1981 cttgttagca gtaacaacgt gttttccagc ttccaaggca cgagtgataa aggttttagc
     2041 aggctcaata cgccccatca attccactac gatagtaata tcctggtctg ataaaatatc
     2101 atccacattg gttacaaagt taaagtcatt ccctgctgca agcaagcgat ttttttcatc
     2161 ttcatccttg accaatacct tagcaacttt gatatctgaa tgtgctgatt gattaatttt
     2221 tcctccattt tcctttagga ggaaaggcac accacttgca acggtaccaa atcctagtaa
     2281 agcaatttta actgtcatct ttatctcctc gaaattttct aatatagcca ttataacaga
     2341 attttgtgaa aattcctatt atagtaaatc actatttcag tataaaaaga aaaaacgaat
     2401 cagacgattc gctcttctta aaatctgaaa atagctttcc agaaaggatt agccgatttt
     2461 ttgcagattg agcactgcat cgtgactcat caagacttga ccatactctt gtaagactga
     2521 gcgactgata tcactatcgt ctgcaaactc gcgcatacgg gccaacagcc aagctggata
     2581 tgggcttgga tgattttcaa tatccactaa aatggtcaaa taatagcgct cgttcatttt
     2641 gtagagttca gaagtttcca tttcaaaagt cactgtcttg gcaaaagcta ccaagtcagc
     2701 caacttagca aaagaaagga tgtagtagat gtaaggttct ttcttactct cagcttcttg
     2761 ttcagcctgc tcttgctctt cttccttggc ttcaacttgc tcaagagatt gaatggcttc
     2821 gatatcatcc ttggttttgt ctgctatgct tttttccagg gttttgataa attcatctgg
     2881 agacatttga gccaattctt ccatatctgg caaatccgat aagtcttcaa aatctagatt
     2941 ttggtcaatc tttgacttgg tcacaaagac atctacctta tcaggttttg gagtcacacg
     3001 gaagctcaac atgcctgtat ccagaaagct atcaggcatc tctagctcat ccaagatagc
     3061 ataaaagaac tcttctgttt tttcttgagg aacgagaaag tcagcaatct ccattccacg
     3121 atccatcaaa tcctctaaag acatcgtgat ttttaaagtt gtatcactaa tttgtttcat
     3181 tttcattgct agtaacctca tactttcagt tctatctatt atactagatt tttacgattt
     3241 tatcaaaaga aggctcctct atacggatag attttcccta gggtctttct ataggagact
     3301 ccaaaagaaa atttctgcag acagatagaa aaagccttca aaatcggctc ttagccgatt
     3361 ttgaagacct tatacatcag aatacttata atttaaaggt tgctacaccg aggatagaac
     3421 gatttaagtt tctgagaatt tgaagacttt gctcaaattt cttataacga gtcactccgt
     3481 actcttcaac aagaaggact gtatctcttt ccaaaagaga tgatacatcc tgtaaatcta
     3541 caaaatgcat tccttttaaa gcttcttgac tctgtttcaa tttatctagg atagctttat
     3601 ttgagctaac gatggtcaat tcctgtccag tatttttgta tgacaaaaca tctgctaggt
     3661 tagcaattgt tgtaatctct gttacaaaat caatttgata ctgagaaaaa tcacctactc
     3721 tattgattgt tggattaaag agataaacta acacatttcc catcacaacc aaaatcacac
     3781 aaaccactcc aataacaact aaacgaagaa tcagattttt cacatttaag ccaagcgctg
     3841 tttcaccatt tgcgttcaat tctttagagt tgatggtttc cagtttttca attttcacat
     3901 ttgcataggc atgtttaaat ttctcaatca acccatcaat ttttttctct aacaagtcat
     3961 tggcatcttt acttgatgtc aaaattttca caccaacccc tgcatcgtca atcatatagt
     4021 agacggtcaa ttttttccac caatagtcat tcgttgaatt tttcaaggtt gtttctgtcg
     4081 tgtctaattc actggcaatt tttttcaact cactgggttc tacatcattg aaaagataag
     4141 ctccattcaa attaccatca atcaatttcc cataaaaatc actataacca ccaatttgat
     4201 gattcaaaat cgttttggcc gactcttttg gaggagtgat tttatagata agataagttg
     4261 aataacttgt tgtatctttg acagtgtttt tattcctaac tgctttaatt gtaaatggta
     4321 cagcaatgag agcaaataaa gcgatgagag ctaaaatatt tgcttttcgc tttttataaa
     4381 gatttgcaaa caaatcagct actgaataat gttcaaacat gatttttttc tcctttgttt
     4441 agtagatact agttttcctt tgtaagcatt tttgctacaa atataatcac aagaacaatt
     4501 ccccagaatt gcattgtaaa taaattgaag aaactttctg aaaagctgct tcttggcata
     4561 aagaatagat tattcaagat gagtagggat aaagcaaata ggattgtcct tgagcgatag
     4621 gctacttgca gcatggctat aaataatacg ccgagtaaga aactaagcag aaagactcca
     4681 atcataccat agtcggtata caactccatg atataactac ttccgatacc atgccctttc
     4741 aagtattcct tgttcaagac aagataggat agattgtggg cataactatt actatcaata
     4801 gctagttcca cactattggt tgtatgttca aaggcttttc ctccgaaaat ggctcccaaa
     4861 ctcccccttg caaaataatc aagaacagga ccaaaagtaa aattacggaa atctcggtaa
     4921 gggaggctac tgttaaatag aaaacctcga gccagaacac caaaactagt tccttgttta
     4981 tagataaagt caagtaagat atcccagaaa cctgtatggg aaacttggac attatcccgt
     5041 acataattaa gtactcccat cgctaacatg agaataggag aacctacaaa aatcgctaac
     5101 ttttctttaa acccaatcca ttttcctttt tcagtttgct cccgcataaa gtaataaaca
     5161 aaagcaaata aaatacttaa aataaaggga tttcgtgtcc caattgccaa atgaatagta
     5221 ttagctgcaa taaaggagac aagcactgct gtggcctgca atttctttgg cttggttgcc
     5281 agatacatac acattgcata gaccgtaaag gtagacaaaa tgtaggtaaa ataaggcagt
     5341 ttactttcaa aatttgcata gtaggcatag taggaagtct gcaaacgata caagagccgt
     5401 tcaaataacc gaatgaaata gaaaggatag gttagaagaa aaactcctag tgatacaaag
     5461 cgtaaccgct tgatataaac ctcttttaga gaatttccta tatttgctac ttttattttc
     5521 ttcctagcta tgaagtaacg agccaggacg cctcctgtgg tcaagcccag aatcgaaacc
     5581 atgacaacta taaaggcaaa acgataggct attggatgat aggtatccaa agcaccatcc
     5641 ctaaaataat caatggtcgg tcttgatacc agaaatacaa aaatggttaa atagaaaata
     5701 aaatggatta agtaatactt gatatcattc caacaagcaa ttaagctact aaccaacaag
     5761 aacaataaag tagaaagtaa gctaacatta ttattattaa acagatacac aattccactt
     5821 actagcgtca aggtataact gactatggtc aaactaaata ataatcgttt cccatcaatc
     5881 acttggtcac ccccgttcta atgtaatttt ttagattttt caatattttt cagtaataag
     5941 aatcggtata aggaaatatt tatgaatagg gccaaagcac taattcttct ccccttacgg
     6001 aaaattggat tcctagaaat agcaaaagca tagcctttta aaaaacgatg aatctgagaa
     6061 taggcttcaa actgtttata ctgatcatct agcaacatct tatccagaat aaagaagtga
     6121 gcataggcca atctgaaaaa agcgacctct ttcaagtcag gatagttttt cacaacttca
     6181 ttataaaact tttggtagat atcaatatag gctaaatcct tctttgcata gggtttggtc
     6241 gtaatactat cccctctatg gaaatagtaa taatagggtt tagtattaac cacatacttc
     6301 ttggccaact tgattaaatc aaaatggtaa taggcatctt cgtaaatcaa ccccttagga
     6361 aaggataggg cagttgcaat ttgtctcttg attagcttat tgcaaatcgt cccaggtatt
     6421 ttttcaccta tgaggtattc ctttagaaat gtttgagaat cacagacaaa atagtcatcc
     6481 tgattggctg actgtgggct ttcatcatta gcatagacat tcatgacacc acagcttgaa
     6541 acatccgcat cttcttgaac taattgctca tataagctct gaatcatttc tggatggata
     6601 taatcatctg agtcaataaa aatcagataa tccccgtgag cctgcttcat cccatcattt
     6661 cgtgcttgcg acaatccttc gttcttttta tgaagcactg acaccctgtc atcttgttca
     6721 gcgattgaat cacacaagcg accactttca tctgttgcac catcatcaac aagaataatt
     6781 tccagatttt gataggtctg cttctgaatg gaagctatcg atttttctag gtactgcgcc
     6841 acattataga ctggcacaat cacactaatt aatgcagttt ccatgctact cctctaatag
     6901 tttttctact tgttcgattt gttttgtaat tgtaaattgt tgaatgaatt ggctagcctc
     6961 atcgacatta aagtttgagg cagaagtcat gtaattagta atcgcctgag ctgcctcttg
     7021 attgctctca atgatttgtc caaatcgtcc ttcttgggat aattcctcag cccctccaac
     7081 gtccgtagag ataaaaggga gtcccagact caaggcctcc acatacactc caggaaagcc
     7141 ttcttgttta gacatagaca agagaacttt cgtctgagat aaatactgat aaggattttt
     7201 ttgataacca aggaaatgta catagtcctc aatctcatac tctttgactc gttttttcag
     7261 ttcctcttcc atatcaccag ccccgataaa atagagatga tagttttttc cctcttggtg
     7321 taataatcgt atcacttcca ctacacggtc agaaccctta ttttcctcaa tccgtccgat
     7381 agtacagata ctttgaggag caatctcgat atcgatcttc tcttgagatt tttctagaat
     7441 agtctgaaaa tcatatccat tgtagattgt ctgtaattta gaagcataat ctggataaac
     7501 ttccttgata gaattgctgg tcttttttga aatccctaca attgtattcg cagcatccaa
     7561 ctggcttcta tgtgattctc ttttagagct atccttaaga agttcttcaa tacttccatg
     7621 aatccaagat atcttcttga cttctcttct tttagagaac aacagtggtg gattcataat
     7681 ggtaaaagaa acttcaacat cataatcatc ttttacaagc aaacgacgag tcagtcttgg
     7741 aaaataaatt ctcattctcc acaaaaaagc tcgtaaccat ctggtttggc gataatcttg
     7801 aagggatttt aaaatgcgta catgctttgg aacagattca tatcccttgt caaagtgctc
     7861 catttcaaga atatcaatat catacttttc tggatccaga tttgaaacaa tggttgatag
     7921 aatcttctct gcaccacctc caagagaaaa agaccacata aaaaataaga tttttttctt
     7981 agccaccata ttctcccttg tattctgtat aagacttatc catatcagcg atgacagcat
     8041 catgatgcgg taccttcttg tctgctggtg gaggcgtcat ataatcccca aaagcagttc
     8101 tgagatagac atcatagccg attggaatag gcatctctgt tccttcaaat ggcaagaaaa
     8161 gattgtcttc aaaagacgtg attgggtact tgtttctcat gtagccagga cctgagcata
     8221 attctgtaat gccatcacaa tcagccaaat catacttagt catttctttc tcagcttttt
     8281 tccagatgcg ataacggaga gattttggag tcaaacccag taaaatgcga cttccccatt
     8341 tcatgagagc accatgcttt tctggaatag tttgcgcaca aaagagtgaa taaatcaagg
     8401 cccaacgaac ctgttttttc cgctcagctg gatttttcgg ataataatcc aaaggcaaaa
     8461 catccaaggc cagaccatgt ggcaaatcca aatcctgctg ataaggcttg atacaggtgg
     8521 tttccttgtc acgaatggta ataaaaagat tacgatcaac aaaatccttg tgactctttg
     8581 acaagaaata acgttcatct gcataacgag gccataattc tgctaatttc tcataatctt
     8641 tacgaggcat aaaaaagtct aggtcgtcgt cccaaggaat aaatcccttg tttcgaaggg
     8701 caccaatagc gcctccgcca cagagataac agagcaaatc atgttcttta caaaaggcca
     8761 caaaatattc agccatctcc agactacgag cctgaattgc ttttaaatca gtcatattgt
     8821 tcattattct ttctatcgta tcgtttcatt ataccacaaa caaggggtga aaatctattg
     8881 cagactgtaa aaaatcaaag cctgactgct atccaaatag ctatcaaact ttgatttttc
     8941 tgtcttatac tcttcgaaaa tctcttcaaa ccacgtcagc ttcaccttgc cgtaggtata
     9001 ggtaactgac ttcgtcagtc ttatctacaa cctcaaaact gtgtttttag cagcctgcgg
     9061 ctagcttcct agtttgcact ttgattttca ttgagtatta tcttatctca agcccatttg
     9121 agcgagcttg gtttgatatt tgttttgatc aaccagcaag cccaagcctc cataaacatc
     9181 ataggcatct acccagtcac ccagttctgg aatcgtcaat ttttcaatac cattttttgc
     9241 tccatccaaa acagataaac cgtttgttag gaggaaagta tagggtacgt tggttgaggt
     9301 catagcaaaa acctttccaa gagcttcaga accagtgaaa agtttagtgg gatctttaat
     9361 ttgctctaaa attgctgtta aaacttgttg ctgtcttttt gtacggccgt aatccgcctc
     9421 atcatcatca cggaaacgag cataattgag cagggtcgag ccattcatct gctgttttcc
     9481 gactttaatg gtttgggttg gagactcagt ctcggtagcg tataaatcat ctccgactgt
     9541 agcttctgtt aggggacgcc cattcaatgt tgaaaattga gcatcaatcg tcaccccatc
     9601 agggaaaagc gtgtcaatcg ctgtggcaaa ggcctggaaa tcaaccaagg cgtagtactt
     9661 aatgtccaag tcaaaattat ctttcaagac ttggcgaacc atttctgccc ctttttgccc
     9721 ctcttgttct cctaactcgt aggctacgtt taacttgtta tctgtctgtt ttctaccgtt
     9781 aatcacttga ctataaccat ctatatagac caaattatca cgcatgaaac tgactagctt
     9841 cattttctta tctgagcccc cgacatttaa taccataata gagtcagttc gtgtctcaac
     9901 actgttctgg ccgattcgac catcagtacc catgattaaa atattaactc catctctagt
     9961 gtcctgacca ttaaagactt ctacttgagc tgcccgggca tcagcagttt tctttgcgct
    10021 agcatcttgg taaccacgca aaaacatgaa taccatggcc aaagccacac agaccaaaag
    10081 tgaaaaaatc accataaaaa ttcgtttaag acggagcttc cgtcttttct tttttggagg
    10141 gaaagagagt gcttgtgatt tggattgtga gcgactccgg ttcgcatagc ttggtaagtc
    10201 aacctgctct tctctttctt gttccaagct agagctacta tttcccctag caagagttag
    10261 cttttcttgc aaataggcaa actcattttt ttctctctca ttgagatagt gaatattttt
    10321 tagcaaataa tcataacgca actgctcatg atgacttaag ggattttctt tactcatctt
    10381 ctctcctttc catggtctga tattggataa ataggatagg cacccagaat tttatactgg
    10441 attccaatcg cttctaattc tttttgggca aagtggacca agtccttatc ggtataatcc
    10501 acatcgataa tgaaaaagta ttcacccagt gctgtcttga gtggacgact ttcaattttt
    10561 gtcaagtcaa ttcctcgcca agcaaaggtc gacagggcct tataaagtgc acctggaagg
    10621 ttgtcaggta atgtcaaggc caaactcatc ttttcagttt gtgcttgcaa gggaatacta
    10681 ggcttttcag ctcctagaac ccagaaacgt gtgaaattgg cttccatttc ctgaatatcc
    10741 tcggcaatca gttccaatcc atattcttca gcagaacttc taggtgcaac tgctgcaaag
    10801 ggctggtctg gatgttcgga aataaaacgg gccgcataag ctgtactagc tgttacctcg
    10861 atttgagcct ctggatattg ttcatcgatg aatttctttc cttgagccaa ggcctgtgga
    10921 tgtgaaaaaa tcttttcaat cttagtatgg cctggaacca ccatcaactg ctgatgaata
    10981 ggctgaacga tttctgctac tgcttggatg tgagcctgat gaaaaagata gtccaaggtt
    11041 tcatgaacac taccctcaat agaattttca actggcacca cagaatagtc cactaatcct
    11101 tgctcataag ccttgatgac atctgtaatg ttagcaaaag cctgcaattc ctcatgagga
    11161 aaagctatct gcacaacgtg gtgtgaaaat gatcccttgg gacctagata agcaattttc
    11221 atcttagttc ctctataatt tcctctgggc ttagcttggt cacatccaaa acccgactag
    11281 ccacttcctc ataccaagcc tgtctttctt gaaaaatagc tactagttct tccttgctat
    11341 tatttagaaa aagcggtcgc tgattgtcct tatcagctgc gatacgttgg tagagggttt
    11401 caaaatctgc tttcaggtag atgttatctg tattagtctt gagtaagtca cgatttctct
    11461 gagaaataac cactcctcct ccagttgaca cgacttggtc tgtttgtagt aaatcagcta
    11521 ggacttctga ttctacctga cgaaaggctg cttctccctt ttcagcgaaa aaattcgcaa
    11581 tggacatacc taggcgcttc tcaatcagag catccatatc aaggtaatta gggtccaagc
    11641 ctcttgcaat agtcgatttt ccagccccca taaaccctaa taacacctta gccatgaatc
    11701 aagctctcca aatcatcaaa gaaactagga tagctggtat tgatggcttc tgcacggtca
    11761 agctccacct ctccatctgc aaccaagagg gctgcgatag ctgtcatcat gccgatacgg
    11821 tggtcaccaa acgtattgac tctagcaccg tgaagagctg atttcccttt gataatcatc
    11881 ccatctgccg taggagtaat atctgctccc atactattta aggcgtctgc cacaacctga
    11941 atacggtctg tttccttgac cttgagctcc tcagcatcct tgataactgt tacaccttgg
    12001 gcttgagtcg caagcagggc aataatgggc aattcatcaa tcaatcgtgg aatcaaagcg
    12061 ccaccaatct ctgttccttt caagtcagaa gactcaacag tcaaggtaga agatttagcg
    12121 actggatcga tttcagttat ttccaatttt ccacccatgg cacgaatgac atcaataata
    12181 ccggtgcgag tttcgttgat ccccacattc tgcagcacta gacgagaatt tggaacaatc
    12241 aaacctgcga ctaaccaaaa ggctgcactg gaaatatctc ctggtacgac caccttctgt
    12301 cctgtcaatt tttgtggccc ttggactgtg attttcttac cgtccacact taaatgacca
    12361 ccaaattgtt tcaacatatc ttcagtatga ttacgggtgc actctttttc gataataact
    12421 gactccccct tagcttgtaa ggctgcaaac atcaaggctg acttgacttg ggcagaggca
    12481 attggcaact cataatgaat aggtcttagg tttttcgtcc cttttaagcg aaggggaggc
    12541 aagtctcgtt cagtttgccc tgaaatgctg acgcccattt ttttcagtgg aagggtcaca
    12601 cggtccatag gacgtttgga aagactatca tctccaaaca tctctacttc gaaatctgca
    12661 ccagcaagga cacctgaaat caggcgaatc gaggtgccag aatttcccat attaagggca
    12721 ttttgtggcg cttttaagcc agccatgcct acaccttgaa tggtaataac cccatcttta
    12781 tcctcaattt caacaccaag gtcacgaaaa acctgcatgg tcgaaagaac gtcttcacct
    12841 cgcagaatat cataaacctt ggtctcaccc tcagccaaac ttccaaagat aatggaacgg
    12901 tggctgatag acttgtcacc tgggacgcgg atactaccat gtaaatggcg aatgtttgtt
    12961 tttagtttca tactggacct catacttgca atacttttac ctattttatc ataaaaagcc
    13021 agaaattcct taaaaattcc tgactttagg atcgttcttt tcttatttca gcaattctga
    13081 aactggttca aaaacaattt tttcaatgtc agaaaggtaa atggccaatt gttgttgctt
    13141 ggtaaagaat tctgacaaga ggctatttcc ttgaatctgt ttaccaaagc cttccatctt
    13201 agcttggaag gacgcatctg gcatttgacc tgtatgtgct agtttttgaa tttcctcttg
    13261 aaaggcaaga tattctgtaa agattttgct tgcctcagca tctgctgcaa tcgcatcttt
    13321 agctgcttta acagccttgt attctggtaa tccgcgtaga ccgcgactga gttcgtttgc
    13381 actatcgtaa atatttgaca tgttcttctc cttatttgat gacgactgta tagtcggtat
    13441 tttctgttat gagatgctca gctctttcca agtcttgagc atttttaaat gaaatttgta
    13501 ggattccgtg aatatcctca cgattttcct cgttgatgtg gatgttaacc aaggaagtcc
    13561 cacgtagcag ttccaaaatc cgcaggatga catcttcttc atcaggaacg tcaacataga
    13621 ggtcgtaaga gctatccaca ccaccacgct tatggatttc catggtctgg cgttgttcac
    13681 gcgcttggtt aaaaaagttc caaatttgct cttcatctcc cttactaatg gcctgaccaa
    13741 tcacttccaa acgttccttg aaatcctcaa ttctatccag aatggtctcg ctattggaca
    13801 agagaatgga ggtccacatt cctggctcgc tttccgcaat tcgggtcata tctcgaaaac
    13861 cacctgccgc aaagcgcctt gccatctcat gctcttgagc atagaccgca gtctgctcca
    13921 tgagactaga agccaaaata tgaggaaaat ggctaatctg agaagtgaca cgatcatgct
    13981 ccttggcatc aatctcgata aaacgagcat gaagacctga aagcagatcc ttcatttcct
    14041 taagcgtgtc ctgacttgtc aggcttgaag gtgtaaagat ataataggca ttttcaaaaa
    14101 gattgacatc tgccgaagca gcccctgtct tgtgactacc agccatggga tgggccccga
    14161 caaagcgaac agacttgcca gccaaatact gctccgccgc atccacaatg gttgacttgg
    14221 tcgaaccagc atctgaaata ataacgcctt ctcgcaaatc caaattggcc aactccttaa
    14281 tgaaagcaat agtttgtttg attggcaagc tgaggataat gacatctgcc aaaggagcaa
    14341 aactagcaaa atcatccgtt gcacggtcaa tcatgccttc tttcaaggcg atatctctcg
    14401 aagcttgact acgattataa cctaaaattt cataatctgg atgatcgcgt ttgataccaa
    14461 gtgccataga ggctccaatc aacccaagac ctgcgatata gattgttttt gccataggaa
    14521 ctccttaata gttctttgta tagtctcggt gtttggctac cgcttctttt agttcctcaa
    14581 gattatctga tgagaatttt tcgaggattt cttgcgccag aaccgttgct acaactgctt
    14641 ccatgaccat tcctgcagct ggaagagcag tcggatcact tctctccacg gttgccttgt
    14701 aaggttcgtg ggtttcgata tccacactca taagaggttt ataaagagta ggaatgggtt
    14761 tcatgacccc acgaacaacg atgggttgcc cattagtcat accaccttca aaaccaccta
    14821 gattattggt acggcgagta taaccgtctt ctttagacca gagaatttca tccataactt
    14881 ggctgccttt acgataacca gcctcaaagc caagaccaaa ttccacccct ttaaaggcat
    14941 tgatagagac aacagcttga gccaatcttg catccaattt tctatcccat tggacatagg
    15001 aaccaagacc aactggaacg cctccgacga ctgtctccac aaccccaccg atggtatcac
    15061 catcacgttt gatttggtca atatagtcct tgatttcctg ttctcgttct tggttaacaa
    15121 tagaaacttc agactgggca gctctttgct taatttcagc gactgtcaga ttttcaggaa
    15181 catcgatttc cttgccacca aagaccacga catggttggc aatctccata tccagctcag
    15241 ccaagaggcg tttggctact gcaccaactg ccacccgcat ggtggtttca cgagctgatg
    15301 aacgctccaa agaatttcgc aaatcatcaa aacggtactt aatcccccca accaaatcgg
    15361 catgacctgg gcgaggatga gtaattttcc gcttgctttt aaggcggtct tcaatgtcct
    15421 ccgcagacat gatgtccagc catttctggt ggtccttatt gatgacatcc atagtaatag
    15481 gcgcccctgt cgtcttcccg tggcgaacgc ccgaagtaaa gacaacctgg tcactctcaa
    15541 tcttcatacg accaccacga ccgtagccac cctgacggcg tctaaggtcc tcattgatat
    15601 cctcagctgt caatggaagt ccagctggaa ttccctcaat aatagctgtt agacgggggc
    15661 cgtgtgattc tcctgcagtt aaatatctca tacactctcc ttattttacc aagtagtctt
    15721 tcatctcttc cagagaaact gggtgaatga tcgctgaacc aagctctggc accaagacca
    15781 atttcaaggt gttaccacgc gctttcttgt catgagtaag agcctgataa agcttgtcaa
    15841 cttcccaatt ttcatagtca acaggcaagc cgaatttctg acacatctct gtgatagatt
    15901 gggtaatgcc agctggcatg aggccttttt cctcagcaac cttggaaatc tgtaccattc
    15961 ccatggcaac agcctctcca tgcatgacct tgccataacc ggcagtcgct tcgatggcat
    16021 ggccaatagt gtggccaaaa ttgaggtaaa gacgaatacc attgtccaac tcatcttcaa
    16081 ccaccatctt gcgcttcacc tgacaagaat gttcaatcaa ggtctctgca tgttccaaaa
    16141 tactctcaac agaaccattc agtcccgtca agagagccca cagttctgga tcctcaatca
    16201 agccatactt gataacttca cccatccctt caatcaactc tctttttccg agggtttcaa
    16261 gaacaagtgg atcaatcaga accccatctg gttgggcaaa ggtccccacc atatttttag
    16321 caaatggtgt gttaacgcct gtctttccac cgatagaaga atcaacctga gctgtcaaac
    16381 tagtcggaat ctgaacaaag tgaatacccc gcatataggt agaggctaca aatccagcca
    16441 ggtccccaac aacgccacca ccaagagcaa cgattccatc gctacgagtc agaccttgct
    16501 tgactagaaa ttcatagact ttctgaacag tagttaaatt ctttctttct tcaccttcta
    16561 agaaatcaaa aacagctacc tgaaaaccag catcttctag gctgagcttg accttctctg
    16621 catagagaga ggctacatgg ttatctgtca caatgactac cttttgcggt tgccagagtt
    16681 ctcgcaacca ctgaccagcc tgggccatac aacctttttc aatctgaata tcataaggat
    16741 gatgaggaat atcgattctg attttcatag gagagtttcc ctttctttat tggtattttt
    16801 ctgttaaaga ctgccaaatc tcttctgtcg gcatttcctt gcctgtccac agttgaaaag
    16861 cttctgcagc ttgatagagt aacattccca gaccattgac tgctggattg ccctgacttc
    16921 tagcccattt caaaaacggt gtttcaaagg gttggtatat gatatctgca actaaaagag
    16981 tttctggtaa gactatgttt tcaggaacag gagaggattg gccatccatg cccacactgg
    17041 tggcattaac tagcaaatcc gactcggcaa tccttgcttg cagttcagaa acatattcta
    17101 aagcacacaa atccacttta aaacctgtct gctcctgtaa cttgtctagg taaggtcttg
    17161 ttttttccat agaaacggaa cgaacaaaga ccgaaatctg actgacgcca tccaaaatag
    17221 cctgtgccaa gattgattta gccgcaccac ctgcacccag cagggtcatc tttttacctg
    17281 aaattgtaaa agaaggcaag cacttaaaaa atcccttgcc atctgtatta tatccaatta
    17341 aattgccatt ctcattgaca accgtattaa ccgcaccaat caagcgcgct tcatcgctca
    17401 gcttatccaa ataaggaatc acctgctcct tatagggcat ggacagattg atgccaaaca
    17461 tctggtagcg acgaatattg gccactgttt ctaccaagtc actcgcttca atctcccaag
    17521 ccacataagc accgttggta tctgtcgcct caaaggctct attgtggatg aagggagaaa
    17581 tagaatgctt aataggattg gcaacaactg cagctaaacg tgtatagcca tcaagcttca
    17641 tccaaaatct ccctgatttt tttcatgcta gctagagaaa tctgcccagg ggcactaacc
    17701 tcatccagac tggcaaaaga ccaactcgaa ccagtcacat ccgcagtgat acgagagacc
    17761 ttgcccacct tacccataga aatggtcaca tattcctgtt caggattgag ggttttaaag
    17821 cctcgtgtat agttcatcaa gtctaagaca tcctgctccg tgtgagccat caccgcaacc
    17881 ttaacaagtt ttggatttag gatcgtcaac tctgacaaga tttccatcat gttctcaggt
    17941 gtttcttgga aattatggta actcaaaaca agatttggga agtccagcat ttcctcaaaa
    18001 acatccttgt agctatagta ctcaaaatca atatagtctg gttgatagag ttgcgcaact
    18061 tccttgatta gatggatata ctcttctgga gaaaggtcga tttctccacc ttcggagcga
    18121 gttcgtagcg tgaaaaccaa ctcacggcct gcgaattttt caaaaatggc tggagctacc
    18181 tgcaaaatcg cttctttagg cagatagtcg gcacgccatt caatgatgtc ggcatccagg
    18241 tacctcgtgt catccagagc ctgagcctcc tctaaacttc ttggcattac tgaaacgatt
    18301 aatttcattt actaaccttc atactaatca ccttgaggta attactactt tcatcttttt
    18361 tattataggc aaaatctgct ggaagaccat atttgtttaa aatctggtaa cttcttcctg
    18421 caaaaccttt atcaatttgt tctgtaaatt tctgacggga aacattggca gcattggtac
    18481 tggcaatgat aatccctccc ggatttaaaa tctcaagact ctgggaaatc aacttgtgat
    18541 aatccttggc cacagagaaa gtttgttttt tattccgagc aaagctaggc ggatctagga
    18601 caatcacatc gtaggtcaag tctttgcgtt tggcatattt gaaatactca aagacatcca
    18661 tgactataaa atgatgctcg tctgtgctga gcccatttgc ctgaaaatgc gcttgagaca
    18721 attctcgtga acgtttggct agatcaacag aagttgtctg gctagctcct cccatggccg
    18781 cagctactga aaaagccgct gtgtaggaaa acatattgag caaggattta cccatagcca
    18841 agccgtcaac taaactaccg cgaacctcat gctggtctag gaaaatgcct gtcatcaagc
    18901 catcattcat aaagacttga tacaggacac cattttctaa aacagtgaaa aagtcaggtg
    18961 cttcttgacc ataaacatgg gcagattcat agtccaaacc cttaaagcgg attttctcat
    19021 aagctcctaa aacctcaggg aaaacctgtc taaaggcttc tgatatagtc tgacgaatct
    19081 gataaacata agagttatac caagaaaaga cggcgtagtc gccataaagg tccactgtca
    19141 gacctccaaa gccatctccc tcttgattaa agagacgaaa ggcagttgtc aaatcatctt
    19201 gatagtaggc gtttctcttt tctttggctt ttctaaacaa cgtttcaaag aaagtttgat
    19261 tgaaggccac cttgtctttg ctgacaaacc agcccaagcc cttgttttgc tgagaaaggt
    19321 aggcagtccc aagaaagttt ccttcctgac cctgcacctc tacttcctga tccttaagat
    19381 tgacattctc aagatcactg gcttctagta aaactagccc cttagcaagc ttcttttcaa
    19441 cccttttgct gactcttatt ctattcataa ctaccattat atcaaacttt tagacaattc
    19501 tcaaaaaaga aactaccctt gcttttttac tcttctttta aaaaatggta tactagactt
    19561 cctgcaaaac taggaagtaa atgtgtaaga atcacaataa aaaatgctct tccgtcttgg
    19621 aggagcattt ctttttatca acgaaaatca aatagcaaac tatgaaacta gcctcaggtt
    19681 aactgtgaga ttataggtag agaggttgaa tcagcaatat gtgtctgtca aatttagtga
    19741 caaaggtagt agaagaaaga tgaagaaata aatctgcttc aataggtatc tggaaaattt
    19801 gattttatag agaagccttt tgttacaaac tcaatatact atcaataaat aatattatag
    19861 aagcaacaat aattataatt tcacctatct gcatcattct atttcgaact ctaaatatat
    19921 gttctatcaa aaatacttgg atcacacaca ttataggaat taacgttttt gaaattgaaa
    19981 aatatcccaa taaataaact ataaacaaca aaaatagaac tatgttatat ttcttattca
    20041 aaacattcct ccctatatat ttttgattac caatcttaat catttacaac tacattctaa
    20101 caaactataa aagcgtttgt cgaactgaat ttatcaagca agcgaccaac cagctcatct
    20161 tttttctatt tctgccaata tgcgtgacag gtaataatga tagccaaaaa tagcaagagc
    20221 aagcaggagg ataagagctc ctactcccaa gctgatggca aggatagggg agagagactg
    20281 aaccaagaat atactcccaa ttacaagggc catcaggatt gcactataaa taaacaataa
    20341 aactatggcg actatgccat ttgaacgatt caccaggtcc gtaatgctac tccaattggt
    20401 tgacagattt ttcacatcct taaaataatg gtgacaagaa aggatgacac tggcaaggat
    20461 ccatgccaca ataaggtaaa tcatcgaaat gatgggcaag cctagatata gagaaagacc
    20521 aagtaaagtc agaattggta aaaaggactg aacagcaaag ataatccaaa atttcacttt
    20581 cacataacga gcaaagtcaa agggtaaact cttcagaaaa tcaacatttt ccctctccaa
    20641 ggacaaggca attgaaggca ggctggtgat attgttattg acaactgcta taaagagagc
    20701 tataaaaaac aagggtaacc agtatggagg atgaatgtct ggaactatct gagaatctcg
    20761 gattttggaa atcagaccga tcatcatgag ataaggaagg aaagcacttg taaaaagcac
    20821 tgtaaccacg ccagtcccct gtcccaagag ggtgaggtgg tagcgtaaaa ccatgcggaa
    20881 aaatcccttt ttagtggttg aaattctctc cttgctgcga cgttcttttt tgaccttctc
    20941 ctcactatta agcaggatca cgtcataaaa acgaggaagg accttctttt tggtcagata
    21001 aagcaggaag agagttagtc ctatccaagc gagcagaccc aatatggctt ctattgaaaa
    21061 aggctccact gctattttgt aaaagatatg aagaggataa aggagaaatg gaatgtctct
    21121 aactttgtca acaatacttc caaaagtcga ctgaagaaag aagataaata ttaaaggtat
    21181 gagaactcct atcccaatca tcacattcga aaaaatagac tgatactttc tgaagaccct
    21241 agtctgagcc aagaaatgta ctgccactac cgtcactaaa gtaacagaga caaataataa
    21301 ggtcaaggac agtagcatca aaggcaaacc cagccaaaga gaaggagcta gactaatata
    21361 gagggctaga aaataagcta ggattggtac aattccagtt agagctggca agaggacaga
    21421 cagtccttta gcaattataa tctctgattc tttaaaagca tagggactat aggaggccaa
    21481 atccttactc tcataaaaga cattgtaaaa tgcagttaaa gaagttgaaa aggcaatcac
    21541 tagtaaaata gcaaccatga aactaaaata aacaggcatt tcctcaaaag gaaaatgaat
    21601 ggctatagta ctaaaaaaga tgagcatcaa gagactggaa aaaatgtaag aacttaggac
    21661 tctagcggaa acatttactt tttttccagt atttttagct tgcttctttc gtgggttagc
    21721 cagattagcg tcttgagatg aatagaggat attgatatca actaattttt taatgacctt
    21781 gagacgcatc tgaaacctcc tcttttctac cagcaaggct aaggtagata ctttccaaag
    21841 actggtctgg gttgtctttt ctcaagtcct ctaccttacc acaataaatc aaatgcccct
    21901 ttttcaaaat agcaatccga tcacagactt gctcagctac ctctagcaca tgagttgaaa
    21961 acaaaactgt cttacctttt tgcgcatgct ccttcatcat ttgcttcaaa tcaaaggcgg
    22021 cctggggatc caaaccagtc aagggttcgt ccaaaaccca aatatcagga tcagacaaga
    22081 gtgccccgat gacaaagact ttctgacgca ttccgtgaga aagagtttca ataacctgat
    22141 agcgattttc agcaaaatca aaaacgttca atagcctagc tagactagcc tccaagtcag
    22201 atctactcag atcataggat gaggcgatca attcccaaaa ttcattggcc gttaagcgta
    22261 aaaataagtc aggcgagtct gctacgtagc caatctttcg tttaatagcc aagcgatttt
    22321 ccgataactc ctgaccgtct accaaaatac gaccactgct gggtgaaatg atactgacta
    22381 gggattttat agtggtcgat tttccagccc cattatgacc aatcaagccc ataatctctc
    22441 cattttcaat ctgcaaattg agattactca aggcctcttt atcaccatac aacttactaa
    22501 cattttgaaa ttcaatcatg ggacaactcc tatctttatc tgtattatat atcgctatac
    22561 tatcactttg atacaaaaaa tcaatacttt attttaagta gttaaaacag tttccttcta
    22621 ttcttacgca aacgtttgcg ctaaccaata ctttatgata gaataaagaa caagattgac
    22681 aagtaagagg aaaaatcatg caaaatcaaa cgctcatgca atactttgaa tggtatctgc
    22741 cccacgacgg tcagcactgg acgcgtctgg ctgaagatgc tccacaccta gctcatctgg
    22801 ggattagcca cgtctggatg ccaccagctt ttaaggcaac caatgaaaaa gatgtcggct
    22861 atggtgtcta tgacttattt gacctaggag agtttaacca aaaagggact gtccgcacta
    22921 agtatggttt caaagaagac tatcttcaag ccattcaagc cctaaaagca cagggaattc
    22981 aacctatggc cgatgtggtt ctcaatcaca aggctgcagc cgatcacatg gaagcctttc
    23041 aggttatcga agtggatcct gtagaccgta cggttgaact tggagaaccc ttcaccatca
    23101 atggctggac tagctttacc ttctatggtc gccaagatac ctacaatgac ttccactggc
    23161 attggtacca cttcaccggt acagactacg atgcaaaacg ccgtaagtct gggatttatc
    23221 tcatccaagg ggacaacaag ggctgggcta acgaggaatt ggtcgataac gaaaacggaa
    23281 actacgacta cctcatgtat gccgacctag actttaaaca tcctgaagtc atccaaaaca
    23341 tctatgactg ggctgattgg ttcatggaaa cgactggtgt agctggtttc cgtttggatg
    23401 ccgttaagca tattgactct ttctttatgc gcaacttcat ccgcgatatg aaggaaaaat
    23461 acggtgacga tttctatgtt tttggtgaat tttggaaccc agacaaggaa gccaatctgg
    23521 actatctcga aaaaacggaa gaacactttg accttgtcga tgttcgtctc caccagaatc
    23581 tctttgaagc cagtcaagct ggcgcaaact atgaccttcg tggcattttc acagatagcc
    23641 tggttgaact caagcctgac aagtctgtga cttttgtcga caaccacgat acccaacgag
    23701 gacaagccct tgagtctacc gttgaagaat ggttcaagcc agcagcctat gccctcattt
    23761 tgttacgcca agacggcctt ccatgtgtct tttacggaga ctactatggg atttcaggcc
    23821 agtatgctca acaagatttc aaagaaatcc ttgaccgcct cctagccatc cgaaaagatt
    23881 tggcctatgg agaacaaaat gactactttg accatgctaa ctgtatcggt tgggtacgtt
    23941 caggtgctga aaatcaatcc ccaatcgcag tcttgatttc aaatgaccaa gaaaacagca
    24001 agtcaatgtt tgtcggtcaa gaatggacta atcaaacctt tgtagattta cttggtaacc
    24061 accaaggtca agttacaatt gatgaggaag gttatggaca attccctgtc tcagctagat
    24121 ccgtaagtgt ctgggcagtc aataccatct aatagctcat aataaccaag ctaggtccaa
    24181 gcggatttgg cttttttgta gtcaaaaaag acctacccaa atggatagat ctttacttga
    24241 ttacaattta cctgctacta catccaataa ttcttggatc ttagcttggt tgcttcctcc
    24301 tgccatggcc atgtctggtt taccaccacc acgtccatcg atgattggtg ctaattcttt
    24361 gacaaggttt cctgcatgaa ggtcttttgt cttgcttgct acaaggacat tgactttgtc
    24421 accgatagcg gcaactagga caagaagatc agagtagtct ttttgtttcc agttatctgc
    24481 aaaagtacga agggcaccgg catcggatac agacacttga ctagcaatgt aacgatgacc
    24541 gttgacttcc ttagcatctt tgaagatatc gcctgcggct gcagctgcgg ctttttcttt
    24601 caactcagca ttttcttttt gaagttgacg aagttgttct tgaagtcctt ctaccttgtg
    24661 aggtacttcc ttgacttgag gtgctttcaa ggttgctgcg acagctttaa gagcatcctc
    24721 ttgttcacga taggcttcaa aggcttcctt accagtcact gccaagatac ggcgagttcc
    24781 tgaaccgatt ccttcttctt tgacaatttt gaagagacca atctcagaag tgttgccaac
    24841 atgagtacca ccacaaagtt caatagagta gtcaccgata gtcacgacac gaacttcctt
    24901 gccgtatttc tcaccaaaga gggccatagc tcccatttct ttagcagtgt caatatccgt
    24961 ttcaactgtc ttcacttcaa gtgcttccca aattttctcg ttaacttgct gttcaatcgc
    25021 acgaagttcc tcagcagtta ctgcttggaa gtgggtaaag tcaaagcgaa ggaattcaac
    25081 ttcgttaaga gatcctgcct gtgttgcgtg gtttccaagg atattgtgaa gggcagcgtg
    25141 aagcaaatga gtcgcagtgt ggtttttcat gacacggtga cggcgattgc tatcaattac
    25201 caaggtatat tcttggttca aggcaagcgg tgcaaggact tcaactgtat gaagggcttg
    25261 accatttggg gctttctgaa cattggtcac agtagccaca accttacctg actcatccaa
    25321 gatttgtccg tagtcagcta cctgtccacc catttcagca taaaatgacg tttccgcaaa
    25381 gataagagag gcagttcctt ctgaaacagc ttctacttct gcattgtccg ccacgatagc
    25441 taccaattta gaagacaatt ggctagcatt gtagttgaag acactttcta cagtgatgtt
    25501 ttgaagagtt tcattttgca tacccattga gccacccttg acagctgagg cacgcgcgcg
    25561 ttcttgctgt tctttcatgg ctgcttcaaa accttcacgg tctacagtca taccagcttc
    25621 ttcagcgatt tcttcagtca attcaactgg gaacccataa gtatcataga gtttgaagac
    25681 atctgaacca gcgataacag attgaccttt ttctttcaag tctgctacaa tgccttgggc
    25741 aaagtgttga cctgagtgaa gggtacgggc aaatgattct tcttcgctct taacgatttt
    25801 ctcaataaag tcacgtttct caagcacttc tgggtagtag ctttccatga tttttccaac
    25861 agttggaacc aatttgtaaa ggaaaggttc gttgataccc aatttttgac catgcataga
    25921 agcacgacgg agaagacgac gaagaacata accacgacct tcatttcctg gaagggcacc
    25981 atcaccgata gcaaatgaaa gagaacgaat gtggtctgcg ataaccttga agctcatgtt
    26041 gtcgccatct tggtcataaa ccttaccaga caatttctcg acttcacgga taatcggcat
    26101 gaagaggtcc gtttcaaagt tggtcttagc cccttggata acagccacca aacgctccaa
    26161 accagcgccc gtatcaatgt tcttatgtgg caattccttg tattcgctac gaggaacagc
    26221 agggtctgcg ttaaattgtg acaaaacgat gttccagatt tcaatataac ggtcgttttc
    26281 aatatcttct gcaagcaggc gaagaccgat attttctggg tcaaaggctt ccccacggtc
    26341 aaagaagatt tctgtatctg gtccagaagg tcccgcaccg atttcccaga agttgtcctc
    26401 aattggaatc aagtgacttg gatccactcc cacttcaatc cagcggttgt aagaatcttt
    26461 atcgtctgga tagtaggtca tgtaaagttt ttcagcaggg aaatcaaacc attcagggct
    26521 tgtcaaaagc tcataagccc aagtgatagc ttcgtcacgg aagtaatccc cgatagagaa
    26581 gttccccagc atttcaaaca tggtatggtg acgcgcggtc ttccctacgt tttcgatgtc
    26641 gttggtacgg atagcctttt gggcattggt aatacgtgga ttttcaggga taatggtccc
    26701 gtcaaagtat ttcttaaggg ttgctacccc agagttgatc cacaaaagag ttgggtcatt
    26761 tacaggaacc aaacttactg atggttctac tgagtgacct ttggtcgccc agaaatcaag
    26821 ccacatttgg cgtacttgtg cactagatag ttgtttcata ttgtctcctt attcacttgt
    26881 ttaatgtgat tggctttcca gcatttccac atagtcaatc gcgacacaga gggaaatgac
    26941 taggtctgca taagcgtctt caagaaccgt tacggtatag gtagaggtca gatggaagag
    27001 ttccttctta atttccgcaa tcaactgatc gcgatcatcc agcaatttga aattcaaatc
    27061 ccagatattg ccctcgatac gaagacctag attatcaaac tcatacttat ctcgccagaa
    27121 ggtcaacttc ttacgaatga caaaactcga gccatcccga agctgaatct caaaacgagg
    27181 aagcaaggtc aagatttctt tactgatctg actgacttgt tcaccagccg catcatagat
    27241 ggtaaaagtt ttgggaatct taaaaaatga tccctccacc tgataggcaa tttctcccct
    27301 gtcatccttg atagcgaagc gttcgcctcc aagacgaaac ttttgtttga caagaaatgt
    27361 tttcatcaac acctccaaaa atcaaaagac aagctcatat cacgaagggc gaaaaaccgc
    27421 ggtaccacct tcattcaatg aacttgtcat tctcttgttc ttatgcaatt gtatgattga
    27481 gtagcatgac ttcctagctt agatggctcg cagcaccgcc atttctctgg actaagacaa
    27541 gtgaaaatca attctcaact ttcttattat aacgtttttt taagcttgcg tcaactggaa
    27601 atgatctccg ttgaattaga ccaattccct acatctctga ttactttttc aggatatatt
    27661 ttttcttact gccatttttc tttttatccc aaattttcat attactaaac acagctacta
    27721 gaatatttcc aaatataaag gtgcctatca cccaatatat ggactcagtt gttaggtatt
    27781 gtcgatccaa gccatccttt aaatggaata gtatagcagt ttggttaaca atcataaagg
    27841 ttggccagaa actttttttg aaaaaagtag acattttcat tatttgttgc cgctttctgt
    27901 aaggttaata ctcaataaaa atcaaaaagc aaactaggaa gctagcctca agctgtactt
    27961 gagtacggca aggcaacgct gacgtggttt gaagagtata ggcttagtat actactaggc
    28021 aagcaaataa gcaaataaac aaataaacaa ctagaataga aaaagatagg gctctaaaaa
    28081 ctgacttcta ttccttaaaa acgaaccagc ttgactgatt cgtcttctta cgtttatctc
    28141 ctacttccga tacattttaa actgtaggaa gaggtcgcta tatttccctg tccatttatg
    28201 gtcaaatttc tcataaactt ctaggtgttt catggtttca acatcgggat agaaggcctt
    28261 atcttccttt gtttcctctg ggagcaattc cttcgctggt aggtttggtg ttgaatagcc
    28321 gacatactcc gcattttgga gagcattttc aggtttcaac ataaagttga taaaggcata
    28381 ggctgagttt tggtttttaa ctgttttggg aatgaccata ttgtcaaacc aaagattgct
    28441 ggcctctgtc ggtaccacat aacgtagatt ttcatttttt tctaacattt ggctggcttc
    28501 accagagaag gtcacgccga ttgcaacatt attctgaatc atatagccct tcatctcgtc
    28561 cgcaacgata gccttgatat ttggagtcag tttgtagagc ttatccactg tctcttccaa
    28621 ctgctgcaga tccttggagt tgaggctgta gccgagggaa ttgagtccta gtcccagcac
    28681 ctcacgcgcc ccatcaaaga gcatgataga attcttatac tccggcttcc aaaggtcatc
    28741 ccaatgctca ggcgcttcat ctaccatggt ttcgttgtag acaattccta aggttcccca
    28801 gaagtaaggg atggagaatt tattacctgg gtcaaaggac tggttgagaa actctggtcc
    28861 gatattttcg attcctttaa tttttgaata atcaagcgga accaagaggt cttcgtcctt
    28921 catcttgtta atcatgtatt cacttggaat ggcaatatcg taggtcgttc caccctgctt
    28981 tatcttagtg tacatggctt cgttggagtc aaaagtctcg tactgaactt gaattcctgt
    29041 ttcttctgta aactgagtca agagttcagg atcgatatag tctccccagt tatagataac
    29101 caatttttga ctatctcgac tattgatttt actatctaaa tgagtcgcaa ttccccacaa
    29161 gacaaggata atcgctgcaa ttcctgctaa aaatgaatag atttttttca tgcttgctcc
    29221 tccttctcac gagagataaa gtaataacct acaactagga taatactaaa gagaaagact
    29281 agagcagaca gggcattgat ttctaaggaa atccccttgc gagcacgaga gtaaatctcg
    29341 actgataggg ttgaaaagcc atttcctgtt acaaagaagg tcacggcaaa atcatccagc
    29401 gaataggtga aggccatgaa gtaacctgca atgatagacg gagtcaggta aggaagcatg
    29461 atttccttaa acatctgaaa ttgactagct cccaagtcat aggccgcatg aatcatgtcg
    29521 ccattcattt ccttgagtcg aggcaagacc atcaagacca cgataggaat ggagaaggcc
    29581 acgtgactag atagaacggt caaaaagcca agtgaaaact tgagttgggt aaagagaatc
    29641 aagaagctag caccaatcat aacgtcaggc gcaaccatga ggatattatt gagtgataga
    29701 aaggcttctt ggtatttctt acgagactgg tagatgtaaa tggcaccaaa agtcccgata
    29761 atggtcgcta tcaaggctga taggaaggcc aagaaaaatg tctgagccaa aatcagcatg
    29821 agtctcccat ctccaaacat ggtttcaaag tgagtccagc taaaacctgt aaagctattc
    29881 atatcatcac cagcattaaa ggcatagcca atcaagtaaa aaatcggcag gtagaggacc
    29941 agaaagacca gtcccagata aaggttggca aattttttca tcgttctctc ctttccttgg
    30001 tcacccacat ggtgatgaac atggtcagga tgagaatcac accgatggtt gaacccatac
    30061 catagttgtc attggttaga aaattctgct caatagccgt ccccaaggtg ataacgcggt
    30121 tcccaccaat caaacgggtc agcatgaaga gactcaaact tgggataaag accgactgaa
    30181 ccccacttcg cacaccgttc atagatagag ggaagatgac atgacggaag gtctcccact
    30241 tagttgcacc aaggtcgtaa ctagcattga tgagattatt atccatatcg tctaagacat
    30301 tgaaaatcgg caaaatcata aaggggagct cgatgtagct tgcgacaaag ataaaggaaa
    30361 aatcggtaaa aagcaactgt tgtgaaccaa ttccgataaa ttccaagaat tggttaatag
    30421 agccattttg accaaaaatc ccgataaaag cataggcttt aaggagcaaa ttgatccagg
    30481 taggaaggat aatcagcatg agccagagtt gacggtgctt gagacgggtc aaaaagaggg
    30541 ctgttggata gctgataagc aaggtcacaa aggtcacaat ccctgcataa agcactgagt
    30601 tgaaactcat tttgaggtag gtcaagtttt gtgacgcaaa gtaagattta taattttcta
    30661 aactaaactg gccttcaatg ttgaaaaagg attgtccgaa aatcaagacc aagggtgcca
    30721 atacaaagag ggcaatccaa agcatgtagg gcactacaaa gagtttagag cttgttttct
    30781 tcatctcttt cctcctcgat cgcattgatc agacctgctt cttgctcttc gatttccacg
    30841 tattcttcga tacgagcatc gaactcttct tcggtttcat tgagacgcat gatgtggatg
    30901 tcttctgatt caaagtccag accgatttcc tcacccacga tggccttacg ggttgagtgg
    30961 atcatccatt catttccaag ttcgtcatag gcgataattt cataatgaac tccacggaag
    31021 agctgggtgt cgaccttaac ttggagtttg ccttcttcag gaagggtaat gcgcaagtcc
    31081 tctggacgaa taacgacctc aacaggttca tttggcttca tcccaccatc aaccgcttca
    31141 aagcgtttgc cgttaaattc gaccaagtag tcctcaatca tggtacctgg caagatgttt
    31201 gactccccga taaaggtggc aacaaagtgg ttgattggct catcgtagat gtccacaggg
    31261 gttccagact ggacaatctc gccatcattc ataacgaaaa tccagtcact catggcaaga
    31321 gcttcttcct gatcgtgagt gacaaagaca aaggtaatgc ccaatcgttg ttgtaattca
    31381 cgcaattcgt actgcatgtc tgttctcaat ttcaagtcca gcgctgataa aggctcgtcc
    31441 aacaagacca cacggggttg gttgatgata gcacgggcga tggccacacg ctgacgttgt
    31501 cctccagaaa gtttgcggat ggaacgtttt tcataacctt ccaactgaac catcttgaga
    31561 acttccgcta cacgctgctc gatttctttc ttatcaattt tacgcaagcg aagtggaaag
    31621 gcaacatttt caaacacatt catatgtggg aacaaggcat aggattggaa gacggtatgt
    31681 acgtcgcgct tgttggttgg aatatcattg atacgaacac cgtctagcat gatatctcct
    31741 gtcgtcgcat ccagtaaacc tgcaataatg tttaggatag ttgatttccc cgaaccagat
    31801 gcacctagaa gggtgtagaa tttcccttct tccaactcaa agttgatgtc tttgagaacc
    31861 ttggtgttgc tgtcttcaaa aactttagag acgtttttga attcgataat tggttttttc
    31921 aattggcata aattccttct ttttcataga ttaaccgatc ggggctctgt caggtcccca
    31981 ctacctcttg cagggagtaa aaccacctgc atacatcttc gctaccgata ggctttcacc
    32041 ccctttccat gacatagcag cagcttttca aatacagctt cctacttgct ttcacccaag
    32101 atccggactt ctctttcaag cgtaatacct gagtgttcct tgactttttc gataaccgat
    32161 tggatcaagt cctcgtagtc tttggccgtt ccatctgcga cattgatcat aaatcctgca
    32221 tgcttttctg acacttctac gccaccgata cgatagcctt tcaagccagc ttctgaaatt
    32281 aactgacctg caaaatgccc gactggacgc ttaaagaccg agccacaaga tgggtattcc
    32341 aaaggttgct tgagttcacg taggtgcgtc aagcggtcca ttttctgctt gataacctga
    32401 tgggttcctg gggctagggc aaatttaact gacaagacaa ctgcaccaga ctcctgaata
    32461 gctgaatggc ggtaaccaaa agccaagtct ttagcagaca gggtttcgat ttctccatcc
    32521 ttggtcaaga ccttacaaga ctgcaagatg tgagcaatct cgccaccata ggcacccgca
    32581 ttcataaaga cagcaccgcc aacgcttcct ggaataccac aagcaaactc aaagccagtc
    32641 aaactatgac ggagggcaat gcgagttgtt tcaatcaagt tagccccagc ttctgcttca
    32701 atggtatagc catcaacaga aacgttattg agcttgtcac acaagatgac aaatccacga
    32761 atcccaccat cacgaacgat gatattgctt gcattgccaa gaaccatcca agggatattt
    32821 tcttggttgg caaatttcac aaggcgcgcc aactcaaaac gatttcgtgg aaagaccaaa
    32881 taatcagcct ctccacctac ttttgtataa ctatagctat gcaagggttc cttaaaacgg
    32941 atatcaattc cttctaagat ttcaagcatt ttttctctta cagacatgtc actcttcctt
    33001 ttacaaaatt cattccatta taccattttt agagacattt gacgaccata aaaatacctt
    33061 gtttggattt tgcataagaa aaagaggttc cccccttttt atgatttttt acaaaagatt
    33121 tccttggttc cataggcgac cagaacgagc tccagtgcta gaatcacttc aaccaagact
    33181 ggatttgtca accagcctac ttggaaaaga gatggtgcca gatcaaagaa ggcatgcaag
    33241 ccataggctg ctaggagata aatccatttc ttctggcgaa cagcttggta aacccaaact
    33301 gtcaaaagta attggaaacc aagcgccaag attcgctcaa aaccaagcaa ataaatctgc
    33361 cagaccgaaa gtgactgaat ggtttttaac atattttcag acagtaattg cataacctgt
    33421 ggattctgag tttgaactgc cgaaagaacg atgtaaagat tgagtaaact aataaggcct
    33481 agaaaaatca actccaagcc accatgccct aggccatagg ccaaggcatc tgccttttcc
    33541 aaacttctct ttttctccaa ccatttgaag aaaacaagac gagccgtttc ctcaaaaaat
    33601 gctgccatgg ctaggccata gataatatag ataagcggat gatcttgcaa gagggcaata
    33661 ctaccgtctt tttgaggatg caaaatcaag atatgcacca gtttttccaa aatctgcgaa
    33721 gagacaaaga aagcgactgc acccaagccc aagacagcta gattaatctg gtatttcttt
    33781 ttggtaaacc aaatgcttcc tatcagaaaa gctagcaaca gcaacatggt aataatgata
    33841 tgaatggtca ttttcttctc ctattctgcc ttttcaatat cttttttcat ctcgtcaaca
    33901 ttgaacttag caaacaagta ttgacggtct tggactggga aacgttggtc caactggtca
    33961 actgctccca cctcgataat gccttccttg atgacaaaat ccatgacatg tccaccgaag
    34021 gtcaaatcat ctgatatgaa gtgcagatgg tagcctgcca cactgacccc atggaaaatc
    34081 tgaggcgtcc agaaaccaac aatagtcccc gcaacattgt cacgactata ttccggttga
    34141 tgggttgcga tatcagcaaa cttggtatcg ggtgttgact taggaatcat acgcacatgc
    34201 atatgtgaaa attccccccg aatcttgata gagcggaaaa gattttcccc atcataataa
    34261 gactcaattc gttctttcaa ttccttgtct gtcatctcaa agcgctggcg gaaaatgacc
    34321 tctgcctgat gcggtaccac tgcagcgtaa ggaataaggg catctggtga cacttccaca
    34381 atttctggct ggtctcctga ctctttggcc tgataagcct tgccatccaa gacaatcaat
    34441 tccccatcaa tggaatccaa ggttcccaaa ccaaggtcac catgttctag caattctcct
    34501 actgtcatag taccaccata aaggccagcc atcaaggctc caagagtatt gtattgaaat
    34561 aatttcactg gttcctgcac gttcttatcc attcactttc ttgtctgtta ttctataaat
    34621 cttactccta agtataccac atttgcccct agatgtgaac gagagaaacg ctctagacat
    34681 tgccaagaag gaaaaaaaag ggtacaatgt aacaaaatca agggaggtct ggaatgaaga
    34741 aacaaagcaa gtacaaagag gtcgtttcct atctgaaaaa tggtatcgag tctggacgat
    34801 ttccgacggg tagtcgcctg ccttctatcc gtcaactgag ccttgacttt cactgcagca
    34861 aggacaccat tcaacgagcc ctgctggaat tacggcacga acaatacctc tatgccaagc
    34921 ctcagagtgg ctactatgta ttagaacaag ggcaacatca agacctagaa atcgaggtta
    34981 ccgacgaaca tgccagtgcc tatgacgatt tccgactctg tgtcaatgaa accttgattg
    35041 gccgagaaaa ctacctcttc aactactatg acaatcaaga aggattagaa gacctaagac
    35101 aatccattca caaactcctc tttgaccaag ctctctactg caaggctaac caactagtac
    35161 tgacttctgg aacccaacaa gccttgttta tcctctctca aatatccttt cctagccaag
    35221 ccaaggaaat cttggtggaa cagccaacct accatcggat gaatcgcctc ttgattgcac
    35281 aggggctgga ctatcaaacg attgaacgag gcattgatgg gattgacttg gaggagctgg
    35341 aaggccactt caaaacagga aaaattaagt ttttctacac cattcctcga tttcactatc
    35401 ccctaggcca ttcctattct gagcaggaca aacgagctat tcttgactta gcagccaaat
    35461 atagtgttta tatcgtcgaa gacgactatc tgggggattt ggactctaaa aagggccaga
    35521 ccttccacta tctagataca gaggaacgcg tcatttatat caaatccttc tcaaccagcc
    35581 tctttccagc cttgcggata acagcactca ttcttccaaa tactatcaaa gaagccttcg
    35641 tggcctacaa aaatatccta gactacgaca gcaacctcat catgcaaaag gccctgtcac
    35701 tctatattga cagtcaattg tttgaaaaaa atcgtttggc tcgcttgacc aatcatgaat
    35761 cttaccaaaa acaaatcgag gaaaggataa ctaaaacacc ttgtcccctt cctcattatc
    35821 ccctacacga tggtttattg ctagacctga gacagtatcc taaaatcgcc agtctcaaac
    35881 acagtcaact gggcttggac ttctttgaag aggcctattt aagcacctgt ccttatcaat
    35941 ttgccaaggt gtccctagac aatctggaaa atgttttaaa ctatttaaaa gcagaattgg
    36001 aatgacatcc aactctgctt tttcttattc ttcaacttca gttaaacttg ctgctttttc
    36061 aagatagctt tggtaagttc cttcatcctt aagtttttgg atgaccttgt ctaccacttc
    36121 tttcaaatca tcactatttt ttctaagagc aacgacattg gcgtcgccgt ccttcatctt
    36181 caagctgaca gttgcgacag ctaagccagc gtttttagca gcataactaa gtgcaacagg
    36241 ctcatccata tgaacagcat ctatttttcc agcctgcaat tcattgactg cttcacccat
    36301 attagttagg gaagttaatt gagcttttgg caattgttcc ttgaccattg attctggaac
    36361 agtccctttt tgggctgcaa tattagcact ttctaggcta gttaaatcct tgtatttttc
    36421 cacatcagcc ttacgaacca agaaactaat cttgttttca tagtatggga ttgaaaaatc
    36481 aaagacttct tttctctcgt cagtagcact aattcctgca actgctaggt cagccttacc
    36541 agtttgaaga ctggtcaaaa cattgtcaaa actcatgctt aagatttcca acttaacccc
    36601 aagttcatca gcgatagcct gagccatgtc gatgtctgca ccgactacct ggttctttcc
    36661 atcaaccaat gattgaaatt caaagggtgc atagtcagga ctggttgcca caactaattt
    36721 ccccttttgc ttaatggcct caacagctga ctgagaacca ttagaacctg actggcaagc
    36781 tactaagaag aaacttgcaa gaaaattaca taaaacaaat atccattttt ttgatttcat
    36841 aaataaacaa cctttctgtt aattttgtat aattataacg atatccaagt tacttgtcaa
    36901 gtgtttttta aatttttatc tcaaaaatat tttttcgttc aaaaaaagga gccatcagtt
    36961 gatttcaagc tcctttttat acagaattaa actattttat agttcgacaa tcttacctgt
    37021 ttcaaagtag acaacccatt cacagatatt tttagcataa tcaccgatac gctccaagta
    37081 ggaaataact tggaaataat cacgacccgt aacaatggct tctggatttt tcttaatctc
    37141 ttcagtcgca aggtcacgga tagtttcaaa atagtggtta atttgctcat ccatggaggc
    37201 cacccggtat gcgtcgtcaa cagaaccatt aagataaaga tcaagtgctg cttcaacaac
    37261 gcttttaact tcacgtccca tttttttaat ttcttcctct acagctggga tgcgttcttc
    37321 ccccttcata cggatggttg cctgggcaat ggctacagcg tgatccccca tacgctccac
    37381 atctgataca gccttaagga cagtcaagac tgtacgcaaa tcttgagaga ctggttgttg
    37441 gagtgcgatc atttcaaatg atttcttttc cagtttcact tcgtattcat ttacttctgc
    37501 atcatcttct atgacctctt ttgccaggtc acggtcatgc gtgacaaaag cacgtaccgt
    37561 acgattgatt tgtgagagca cttcttgtcc catagcgtag aactggttat gtaatttctc
    37621 taaatcttct tcaaattgag atcgtaacat ctttcatctc cttatccaaa ttttcctgta
    37681 atatagtctt ccgtttcctt gtgttgggga tcaaggaaca tctgcttggt atcattaaat
    37741 tcaatcaaat ctccatctag gaaaaatcct gtcttatcag agatacgtga agcttgctgc
    37801 atggaacggg ttaccagaag catggtgtac ttgtctttta gaccatacaa ggtttcctca
    37861 attttaccag ctgaaatcgg atccaaagcc gaagttggct catccaagag gatgatttta
    37921 ggactagttg ccaagacacg ggccacgcag acacgctgct gttgaccacc tgacaatcca
    37981 atagctgaat catatagacg atccttgacc tcatcccaga tagaggcacc ttgcaaggct
    38041 ttttctacgg cttcatccag aacctgctta tccttaattc cattgatacg aagcccgtag
    38101 acaacattct catagatagt catagggaaa ggattaggtt gttggaaaac cattccgatt
    38161 tccttacgta attcaaccgt atctgtacgc ggactgtaga tgttgtgacc attgtacacc
    38221 acggatccag ttgtggtcac ctctggattg agatctccca tgcggttgag agacttgagg
    38281 agggttgact tccctgatcc agatggacca atcaaggctg taatttcctt aggttggaaa
    38341 gatagggaaa cactattcaa agccttcttt ttattataat aaacggacag gtctgatacc
    38401 tgtaaaatcg catctgtcat acggtttcct ttctaaccaa agtgaccaga tacatagtca
    38461 ttggtggact gtagcttggc attttggaaa atagttgcag tcttatcata ctcaatcaaa
    38521 tcacccaagt aaaagaagcc tgtatagtca cttgcacgag cagcctgctg catattatgc
    38581 gttacaatga tgatggtaaa gtttttcttg agctcaaaca tggtctcttc tagttgcatg
    38641 gtcgcaatcg gatccaaggc tgaggctggc tcatccatta agaggatatc tggcttaaca
    38701 gagatggcac gagcgataca gagacgttgt tgctgaccac ctgataaggt caaggctgac
    38761 ttgtggagat cgtctttaac ctgatcccag agggcagcct gacgaaggga ggtttctacg
    38821 atttcatcta ggacttgctt atccttaact ccagcacgtt catgcgcaaa ggtgatatta
    38881 cggtaaattg acttagcaaa tggattgggg cgttgaaaaa ccattccaat gtgtttacgc
    38941 atttcataaa cgttgatttc tggacggttg acatcaattc cacgatagag aatctgccca
    39001 gttactttag caatatcaat agtatcattc atgcgattga gactgcgtaa gtaggtagat
    39061 ttccccgacc ccgacggacc aatcaaagct gtaattttat ttctttcaaa ttgcatatca
    39121 atccccttaa tggattcatt tttaccatag taaacatgga catccttagt agaaagggct
    39181 actttttctt caggaaaggt aaggatatgc ttctcatccc agttatatgt tgacatggct
    39241 tctcctttag gcagcggtta atttcttgtg tagatagctt ccgaacttac gagctccaaa
    39301 gttaaaaatc aggataaaga tcaggagcac agcggcagaa cctgctgata caatggttcc
    39361 atctggaata gtgccttcac tattgacttt ccagatatgg acagccaagg tttctgcttg
    39421 acggaagata gagatggggc tagtcacact gaggatattc cagttagacc agtcaagagc
    39481 tggcgccgat tgccctgctg tatagatcag agctgcagct tcgccaaaga tacgaccaga
    39541 tgccaagacg acacccgtta caatacctgg aagcgcttct ggaataacaa catgaaccac
    39601 tgtctcccag cgagaaatcc caagagccag accagcctca cgttgggtat ggtgaacgtg
    39661 tttcaaacta tcctctacat tacgcgtcat ctgaggcaaa ttaaagactg tcaaggccaa
    39721 ggcacctgaa atgattgaaa atccatactc aaactggact acaaagatca agtaaccaaa
    39781 gagacccacc accactgatg gtaaagagga caagatttca atacaagtcc gcacaaagtt
    39841 ggtaacagga ccttttttag catattcagc caagtaaatc ccagctccca tagaaagagg
    39901 tacagaaata atcaaggtaa tgaccaatag gaaaaaggaa ttgtaaagct gaatgccaat
    39961 cccaccacct gcttgaaaag cagaagacct tccagtcaag aaagaccaag agatatgggg
    40021 caagccccga accaagatat agagaatcaa ggaagccaag attgtcacaa tgatgctagc
    40081 aatcgtatag aggacagctg ttgcaagttt atctaatttc ttagcgcgca taatttttct
    40141 ttcctctttc tttcgtaatc aatttaatca cactgttaaa aactaaactc atcaagagca
    40201 gtaccaaggc cagtgaccag agaacattat tatttacagt tcccatgaca gtgttcccaa
    40261 ttcccatagt taatatagaa gttaaagttg cagctggtgt ggtcaaggaa gttgggataa
    40321 cagctgagtt tccgacaacc atctggatag ctaaagcctc accaaaggca cgcgccatcc
    40381 caaagaccac tgcagtgaaa ataccagaac gggccgcctt caagatcaca cgccagatag
    40441 tctgccagcg agtggctccc atagcgaaac ttgcctcacg ataataacga ggaaccgcac
    40501 gcaagctatc cgttgtcata aaggttacgg tcggcaaaat catgacaaag aggacggaaa
    40561 tccctgacaa aatcccaaaa ccagtcccac caaagacact gcgaacaaag ggaacgacga
    40621 cttgcaagcc aataaatccg tacactactg aaggaatccc aaccaggagt tcaatagctg
    40681 gttgcaaaat cttcgcccct tttggtgata cttcggtcat aaaaactgct gcaccaatag
    40741 caaagggtgt tgcgataagg gctgagagaa tggtaacgat aaaggaaccc aaaatcatag
    40801 gaagggcacc aaattcttta ctagaaggat tccaagttcc tcccaaaaga aagtcaaaga
    40861 tattcacacc attgacaaag aaggtcgaca agcctttttg cgctacgaaa accaaaatca
    40921 tggccacaag gatgactatc aaagaaagac aggcaaaggt caaacctttt cctaatttct
    40981 ccagacgaga attctttgat ggaagcaaca ttttcttagc taattcttct tgattcatta
    41041 ttgtctccct tccaacactg tcacagttcc ggcagcatct ttttcaacct tcatttcctt
    41101 aatcggaata tacttcaatc ctttgacaat cccttcttgg gtctcatccg agagaacaaa
    41161 attgagaaat tctgcagcta actcattggg ctgccccaat gtatacatat gctcataaga
    41221 ccacaagggc caattattgc tacttatatt ttctggactt aagtcatagc cattcaactt
    41281 catgcttttg accgaatcat ctatataggt aagagataaa taagagatag ctcctggact
    41341 ttttgatacg attgatttta ccgctccatt tgaatcctgc tcctgacttt gcatggcaga
    41401 ctgaccttcc ataatgacag tatcaaaggt agcacgagag ccagagccgg ctgcccgatt
    41461 gataacagag atgggtaagt ccttaccacc aacctctttc caattggtta cctcacctat
    41521 gaagatttga cgaagttgct ctgtcgttag attatcaaca tcaacctcct tattgacaat
    41581 cagagccaag ccagctaccg cgaccttgtg gtcaacaaga gcagaagcat caattccgtc
    41641 tttttcctca gcaaatacat ctgagtttcc tatatcaact gccccagact gaacctggga
    41701 caagcctgta ccagaacctc ccccttggac attgaccgtt tttccaacat ggatcgtgcc
    41761 aaattcatct gccgctactt caaccaaggg ttgcaaggca gttgagccaa cagccgttat
    41821 ggattctcca cgatcaatcc agctagcaca gcctactaaa caagccgtca gccaaaaagc
    41881 gataagagac agagcaagct tttttctttt tttcactgtt tttctcctcg aaaataatta
    41941 tgaatactgt gaatttttta agtagttctt tatgagttga cgcatgaatt cttaccaaat
    42001 ttctgcgcaa ttgattattt atataatata ggctatatta ctctttccta acctcctttt
    42061 ttcatatgtg gataaaatct cttgtctatc ccttccccca ttgtcaccca ttatagtcat
    42121 ttcgtgtctc tttttcccct ttttaatgca agggaaatta ctctccttag atgataatct
    42181 aaaagctaga aaggtatctc aaatctctct actctcccag actagtttac aactaaaagg
    42241 aaaagattct attttatgag aaatctagtt tacaagcggt aagaacgcta ataactaaac
    42301 ttcttgtact ctttgaaaat ctcttcaaag cagtgttttg agctatctat ggctagcttc
    42361 ctagtttgct ctttgatttt catcgagtag taaaactaca tgtgatggca atcaagatat
    42421 caagaatcat cctactaaaa aaatccatac tttcactata acatagaata agatatttga
    42481 ctagcatttt catttgaatc tgaggccttt tggaaaataa tttttcaaaa catttccagt
    42541 aacctttgca aagcccaagc cattgccttt aaccaaaact tggtaccaac catttggcag
    42601 actttctgcc agctgaacgg tttctccagc cgcatacttg acaaactctt cttggccaat
    42661 ttcaaccgac tgttcgacct gactcggttt caaggctaaa ccaagagcga aactgggctc
    42721 aaagcgtttc ttcttaaaag tacccagatg cagtccattg cgagcaatct tgagcttccc
    42781 taaatctggc aaaagttctg gcaagagata aagctggtct ccaaaaatct gcaagatacc
    42841 cggtagattg accttcaaat ggttttgggc aaattcctgc cacaaggcaa cttgttcacg
    42901 gctgaggtta ctcttacttg ccttaaattt aggagctgga ttgttaccct taaactgtag
    42961 atgggcaaca aactgaccct ctcccttaaa ctgatgaggg tacatccgag ccgtttctgg
    43021 caggtcaata ccagctacca ttccattgat atgctctact ggcaacaagt caaaatcata
    43081 ctcttccagc aaccaattga caatctcttc gttttcctcg ggtgcccagg tacaggtcga
    43141 ataaaccaga cgaccacctt cagctaacat ggtcactgca tcctccagaa tttctctttg
    43201 caagctagca cattgactcg gataatctaa gctccaatag tccatagcat caggttgctt
    43261 acgaaacatt ccttcaccag agcaaggggc atcaagaacg attaagtcaa aatagccttt
    43321 aaagaccttg accaagcggt cggcagattc attggtcacc acgacatttg tcgctccaaa
    43381 acgctccatg ttttcaacca aaatcttagc ccgtttgctt gaaatttcat tggaaacaag
    43441 tagcccctcc cctgctagat aggctgccag ttgagttgat ttgccccccg gtgcagcagc
    43501 caagtccaag accttcatac caggactggg ttgggctact tgagccacca tttgagcagc
    43561 aggttcttgc gaataaacta aacctgtagc atgctcaggc gatttccctg aaaccttccc
    43621 atagtggccc caaggggttt gagtaatggc atcagaaaag gaaagttgct cttcttttaa
    43681 gggattgacc cgaaaggccg aaaccgcttc ctcctcaaaa gaggcaagaa aatctcttgc
    43741 ctcatctcct agtatttctt tatatttttc aacaaatcct tctggaaatt tcatttaagt
    43801 tcttttcctt tcgtaaatat aggactgaat ttcctcctgc atctcaagag gcaccatcat
    43861 gaccggctgt ctggtttgaa aatcaggagc ttcaccaaaa agggtcacaa cccgatagcc
    43921 cagactttcc cctaaaatac tagctgcggc ataatcccat ggttgcagat aggtgagata
    43981 ggtcaacaaa cgccctgaca aaatcttggc aaaactaatg gccgcacttc catagacacg
    44041 aacaccaaga accgctcggc tcaaatcagc cagcccccat tcattggttt ccagcatacc
    44101 actattccct gcaatgagaa aatctccaag tggtttagtt ttaaaagaag ctaggggcct
    44161 atcatttaga caaactggaa attccccacc accgtggtaa caatcccctt tgaccacatc
    44221 ataaatcaga ccaaactgtc cctgaccatt ttcaaaataa gccatcataa cagcaaaatc
    44281 ttcctgctgg gctacaaaat tattggtacc atcaatggga tcaatgaccc aaaccttgcc
    44341 ctcttgaacc gaggctcgca gacaaccttc ttcagcacaa atcttatcct caggataacg
    44401 ggacaaaatc tcaccaacca agagttcctg aacttctttg tccagtctgg tcaccaaatc
    44461 tgttggagag gacttggttt caacacgcaa gtcttcctgc atatggtcaa gaatgtactg
    44521 acctgctttc ttaacaagct ctttagcaaa ttcaaattta ctttccaaga gaaatctttc
    44581 cttccccttt ttctttggca gcctgaactg ctcggtaaag tgaatagcca ctaaccgttt
    44641 caaattctcg tcccaaacgt ttctcttcgc tcttgcttgg cacgaccgct ttgaatccct
    44701 tataggagtc cagtaacttt ttagcctcta ctttgccttc ataggcagct tcaacatcat
    44761 taaaaaaaga aagcactgaa gcaagttctt cagtgctcca cgacaaatct agtgggtaac
    44821 tatactgttt gttcattaac taataccagc tctcattctt gcttctttta gttcttgctt
    44881 acgataacta cgagggagaa aagcacgaat ctcatcttca ttaaaaccga tttgcatacg
    44941 cttggcatca ataataattg gacgacgcaa aagactagga tactgctcaa tcaaatgaag
    45001 caattccgat accgaaatac tctctacatc aatattcaat ttttgaaaaa tttttgaacg
    45061 agttgaaatg atgtcatcag taccattttc ggtcaaggaa aggatttgtt gcaattcttt
    45121 tcttgttaaa ggactggtca taatattgtg ttccacaaag ggaaccttat gtttttctaa
    45181 ccaggcctta gccttacgac atgatgtaca gctcggtgat agaaatagtg taatcatgct
    45241 tttctcttct tatctatact ttgctacttc tattatacaa aaaaataagg cgcttgacta
    45301 gggattttta gaaaaaaaag cctatttttc aagaaaaata ggctgtttgc gaacgattga
    45361 cacaattgga tttggttaat tcactcttaa cgatggtttt aaacgatata tatttttata
    45421 tatgcaaatt aaaaacatct ttcatttcat ttcctacgac ttttcagaca cagatagcca
    45481 aagaagcttt catagagggc aaaaaagagg aggaaggcat gaagaaagaa ggtctctggc
    45541 aaaatcataa taacaggatc cttggctgga tcaaaaagcc aggtatcatc tcccacaaag
    45601 agaatttgat ggaaaagagt aaagaattgg tcaaaaccaa tcaaaactcc cccaagtcca
    45661 atcatcacag gtaagactac tagagtcagg agactttttc gataaagaga caaaaagtcc
    45721 tttttcacaa ttctattgac aaagacatag aaacttggca gtgtcactag agctactagc
    45781 tgaaccaaat gaaagagatt cttgaccact gcgaaatggt gcagaccagc tgctgacgaa
    45841 cgaaaatcag gcatctgtaa gacctgacta aaaggattgg tcagataatt catcaagata
    45901 tgaaaattgt attgaatggt ttctggtttt agatagactc gattcgttaa gtttagccac
    45961 tgaatctcca taggatagaa aatccaagcc agataaatgg tcagaaggat tgagagggag
    46021 aggagaaaga gcatagagcc ccaaaaggtc aatttagttt tcatcaaaat cccactccgc
    46081 aaggctagaa accacatgtg tcggtgcgat tggcaggcca gctacttctt ctgccttagt
    46141 aaaacctgtc gtcaccaaga gcgttggaat gccattgtca atcccagccc ggatatcagt
    46201 caaataattg tccccaacca tgattaactc ttcacgttcc aaacctaagt gctcaaccgc
    46261 cttgtccata atgatggcat tgggttttcc gatataaacc ggcttcactc gtgtcgctac
    46321 ttcaagcagc gtaatcagtg agccagcacc tggcaaaaga ccgcgttccg tcgggatgtt
    46381 gaggtcagga ttggttccga taaaatgggc acccttttga atagcaagag ttgctgtggc
    46441 aaatttttca tagtcgactt gccaatccag accaactacc acgtaggcag ggttttcctt
    46501 gtcttccaca taaccagccg ccttgatggc ttccttgagt cctgcttctc cgacgacata
    46561 gacggtcttt tcaagcccca aatcattcat atagtcgatg gttgctaaag tcgctgtgta
    46621 gacagtcgat aggggcgtat cgatattaaa attctgagcc aacatctcct taacactctc
    46681 tggagtgcgg gttgtattgt tggttacaaa gagataggga atgtcccgct tttgcaattc
    46741 atgaacaaaa gtctctccag cagggattcg gtctttcccc ttataaatgg ttccgtctaa
    46801 atcaattaaa tagcctttat atttcatcta tttctcccta agcctttttt atttcttgcc
    46861 aagtaatgat tgcttgggca ttgataaccc catcacttgt aatttcatgc ttgctttcca
    46921 gtccagtccg ttcaacagcc gatgtaatca ccccacctgg tcgaacttcc ttgacatact
    46981 tgaggttgat tttcttggga atatagtggg tcaaaaaatc cgctcccatg acctcaaaaa
    47041 tccagtccaa gtatttactg ttattgacat gaccattcat atccaagtcg taaaaacgaa
    47101 catggtaatc cttgctgatc ggctcttcca aggattcata cttcggtcca cggataagtt
    47161 ttttatcaaa atcagactgg taaggagcca caatctcagg ttcaacaaca tggacttttc
    47221 gactgtcgcg gtccatgaga acaaaggtcg ccatcatgtg gatgagctcc tgccccgctt
    47281 cattataaat agtaaagcga cggtagcaaa aaagtcgatt gtagctcaag gcttccgttt
    47341 cgatggtaat ttcttccgca aaacgaggca aacgaaccac ctcaatatca tattctgcga
    47401 taatccagac cagattatag tcttccaaaa tggccttatc actaactccc agttcaatcg
    47461 attgcatccc tgaaacttgc agtgacagca aaatcacatc tggaagtttg atatgaccgt
    47521 tcatatcagc catatcaaaa ggaattttca ttttcatttg ataagttaag cccatgatcc
    47581 tactccaaaa taaatcgttc tgctacagta tctcccaaaa agagacctct ctttgtcatg
    47641 cgaacgtggt caccctcaat ctgcatgagg ccttgttgaa ccaagtctct gacaatttct
    47701 ccataaagtc cagcaaaaga ctgtccaaat ttttcctcaa atcgcgccat ggaaaccccg
    47761 gatttcttgc ggagtcccaa gaacatttct tcttccattt gctccttttg actcaggtga
    47821 tcttctgtaa tacaagcatt gccttcctca accgcactga gataatgacg aatgggacca
    47881 taatttttat aacgtactcc attgacataa ccagatgccc ctgcaccaat accatagtat
    47941 tcagcattgt cccagtacat gagattatga cgactttcaa agccgggttt ggagaaatta
    48001 gaaatctcat aatgctcaaa acccgctcgc tccagctctg caatgatgta ctcaaacatc
    48061 tccgcttcta gttcctcctt aggcagaggc aatttcccac gtcgcatccg gttcataaag
    48121 accgtatggt tttctaaaat caaactatac aaactcatgt ggggaatatc caatccaatg
    48181 gctttagcca cattttcctt tacttgctcc atggtctgac caggcagagc ataaatcaaa
    48241 tcaatggaga tgttgtcaaa accagccagt ttcaggcgat cgatattttc ataaatatcc
    48301 ttctccaaat gactgcgccc aatctttttc aacatcttat catcaaaggt ctggacacct
    48361 agcgaaacac gattgacagc cgaatttttc aaaacagcta tcttatccgc atccaaatcg
    48421 cctggattgg cttcaatggt caactcttcc aagacagaca aatccaagtt tttagtcaag
    48481 ccattcagta acacctccag ttgcggagcc gacagggctg tcggtgttcc accaccgata
    48541 taaagggttg acaacttttc aatatcataa gaacgaaact cttccagcag atgctctaaa
    48601 tagctgtcga ctggctgatt tttgatgaag acctttgaaa aatcacaata ataacaaatc
    48661 tgggtacaaa atgggatgtg cacataggct gacgttggtt ttttctgcat agtaattatt
    48721 ataccacaaa gactagattc cagataaaaa tcaccatccc cagatacata gtccgttcgg
    48781 agatggtgat ggtttattct tctgttatat caatcacaat ctcttctgag tcatcaagag
    48841 cttcggcttt ttcttgccat tgttccttga gattatttaa ttgatttttt gatgcttctg
    48901 tcgcttgaaa agcataggat ttagcttgag caagtatact gtccacagtg atttcacctg
    48961 actcaacctg ttcttttgtt ttcagaacaa aatctgtagc ctgctcctta acttctgtca
    49021 gtttttcaca gacttgctcc ttggcatact ccggatcttc tctcaaatca tctagaaaat
    49081 cttgagcctg actgcaaact tgtttgccct tatcacttgt taaaaacaag gcaagagctg
    49141 cacctgaaac ggttcctaaa aggattgagg ataatttacc cataaggatt ctcctttttt
    49201 attttttgaa aaatttactt gcaagacgaa gagctgacag acttgcacca gtcttgagtg
    49261 tttttgaacc agctgatgaa gctttcttgc tcaagacacg cgcatggtca ttgaggtctg
    49321 aaacagatag agataaatct gcaacagcac tgaagagtgg atcaatcgta gccaccttga
    49381 cattgatatc atctgccaag acattgacct tagccaacaa ctcattggta tgatgcaagg
    49441 tcacatccac atctgaagtc aaggttttaa tcgtcttttc tgtttcatcg atgacacgac
    49501 caagcttttg tacagtaatg atcagataga ccaaaaagac aatcaaagct agggcaacaa
    49561 gaatatatgc aacttctaac atttagtttt cctcctctgt aatatagtaa ggggccttct
    49621 ttcgattttg ataaataacg atcattatac cgagaccgat aaggacaact gacagccatt
    49681 gggacactcg aaggccgaag aacatgagac tatctgttcg cataccttcg atgaccatac
    49741 gaccgaaacc ataccaaatc aagtaaaagg ccgtgatatg acctcgtctg agactcttcc
    49801 atttccgtct aaaaatcaga atcaaggcaa agccaagcag attccataga gactcataaa
    49861 ggaaagtcgg ttgacggtag ctcccctcaa tatacatctg gtcacggata aagccaggta
    49921 gataatcaag attatccact gttgcaccat aagcttcttg gttaaagaaa ttaccccaac
    49981 gccccaaact ttgagcaatc ataacgctag gcgccgcaat atctagaaaa tcccaagtat
    50041 tgatgagttt acggtcagca aagatataga gcacaagagc cccagttatc aaaccaccgt
    50101 aaatggccaa accaccattc caaatggcaa aaatctctcc taaattctga ctatagtaat
    50161 caaatcggaa aataacatag tagagacgag ctcctaaaat agccaaggga aaggctacta
    50221 agataaaatc taaaatatcg tctggtatga tcttctttct aggtgcttct ttcatggtca
    50281 aataaaccgc aagaatcaag cctgtcacaa tacataaggc ataccaacga atggctaggg
    50341 gtcctagttg aatagcaatt ggatcaagca ttttgcacct catttcgagc gattagactt
    50401 gtcagtcgtt cgtcgaacaa acgggtcgca tcaaagccca tttccttggc acgataattc
    50461 atggcagctg cctcaatcac aacagagata ttacgacctg ttttaactgg aatacgaata
    50521 cgaggaatgg ctacgccaga aacttcaagt tcctctgcat tgtttccaag acgatcaaag
    50581 gtcttatgtg tatcgtaatt ttccaaatag acagcaagct gaacctgtga agaatccttg
    50641 acagcactcg caccgtagag actcataaca tcgataatac caaccccacg aatttcaatc
    50701 aagtgtttca aaatttcagc tggttcaccc cagagagtaa tctcatcctt ggcaaagata
    50761 tcgacacggt catcggctac caaacggtga ccacgtttga caagctcaag acctgtctcg
    50821 ctcttaccaa ttccactatc tccctgaatc aagacgccca tcccataaat atccatcaag
    50881 acaccgtgca cactggtacg ttctgccaaa cgagaatcca gatagctaga taactctcca
    50941 gataaacgac tggtagctgc acggctggtt aaaatagcaa tcttacattc tctagcagcc
    51001 tttaacatct cctctggaac caccaaacca cgggcaacaa tgactgctgg tgtctcaggt
    51061 agaaacattt ttttcaaaac ttcataacgg ctgttggaag gcatgctgat cagataagac
    51121 cactccttca tccccaaaag ttgaatccgc tctggtgtat agtagtcaaa atagcctgtc
    51181 atttcaagac caggtcgcgt aatatccgct atattgattt ccttttcaag caattctggt
    51241 tcaccataga caatgtctag tctaagcttt tcaatcactt cttttactaa aaccgacatc
    51301 atttcctcct tcaaatgagt tcttctctct attatatcaa attgtaggag gaagtttcag
    51361 atttttgcag gctttggagt atttatttaa aagaaaaagg actagatttc tctagccttt
    51421 cattccaatt agaatttttt acgtttacga gctacttctg atttacgttt acgttttaca
    51481 gaaggttttt catagaattc acgtttgcgt gtttcttgaa gagtaccagc tttagtaacc
    51541 gcacgtttga aacggcgaag tgcgtcgtca agagattcat tcttacgtac tactgtttta
    51601 gacatttttt tcactccctt caagttcaat atctatttca ttctacacgt aaaaggaata
    51661 attgtcaagc aaaaatgcgg tttaattttg attttttctt ccatttatac aagagttgaa
    51721 agcgttcaat agaacattgc ttttttattt ttcgagtaag ctaagcgctt cagcatctgc
    51781 gatgatggtt acatcagggt gattttggag gctacttgca ggtaggttct cagtcactgg
    51841 gccagatact gttccggcaa tggcttctgc tttcgactca ccgtaagcaa aaagaataat
    51901 agacttggca tccaaaatgt ttttaatccc cattgaaata gcttgggttg ggacgtcttc
    51961 aatcttggca aagaagcgtg cattggcttc aatagtagac tggtcaagtt ctactagatg
    52021 cgtttgactg tcaaatggag taccaggctc attaaagccg atatgcccat tgcgaccaat
    52081 tcccaagatt tggaggtcaa ctggatggtc agccaaaatt tggttgtagc gttcaacttc
    52141 agcttcagca ttgtccttaa caccacgagg caagaaactt tctttaaatg gtttttggtt
    52201 gaacaagttt tcttgcatga agtaacgata agactgtgga ttgtccccat caaggcccac
    52261 atactcatca aggttgacac tggttagatt tgaaaaatca aggtcactct caacaatttc
    52321 cttgtaaaat tcaagtgggc tacttcctgt cgcaagtcct agagtttgag ctccattagc
    52381 caatttttcc ttcaaaatct caaaagcaac ttttccacct tgaacttggt tttcaacttt
    52441 aataactttc atcttttcat cctccatttc tgtctatatt tattatatgg tatagaccaa
    52501 tttttgtcaa gtgaaaacga tttaatttct aaaaaaagag cgtccaaact tgaaacgtgt
    52561 tataatggat aggattataa cttagaaaga atgaacaaat atatgaatac agctgatttt
    52621 gatttccact tgccagagga attgattgcc caaacgcccc ttgaaaaacg tgatgcctcc
    52681 aaactcctca tcgtcaaccg tgagacagga gaaatgcaag ataaacattt ccactctatt
    52741 attgatatgc tggaacctgg tgatgccctt gtcatgaacg acacccgagt tctccctgcc
    52801 cgcctctatg gtcaaaaaat ggagacagga ggtcatgtgg aacttctcct ccttaagaac
    52861 actagtggag acgagtggga agttctggct aaacctgcca aacgcctcaa ggtcggtact
    52921 cgtatcagct ttggtgatgg ccgcctcagc gctgtcgtta cagaagaatt gacccacggg
    52981 ggacgcattg tccgctttga ataccaagga attttcctag aagtcttgga aagtctggga
    53041 gaaatgcctc tgccacctta tatccacgaa aaattagatg accgtgaacg ttatcaaacc
    53101 gtctacgcca aggaaagcgg ctctgctgca gcaccgactg ctggtcttca cttcaccaaa
    53161 gaactgctgg cagaaatcca agctaagggt gttcatctag tctatctgac tctccatgtc
    53221 ggactcggaa cctttagacc tgtttctgtg gataatctgg acgaacacga aatgcactca
    53281 gagttctatc aactttctga ggaagctgct gccacccttc gctctgtcaa agaaaatggt
    53341 ggtcgcgtca tcgctgtcgg aaccacttct atccgcacct tggaaactat tggttccaag
    53401 tttgatgggc aaatccaagc agattctggt tggaccaata tctttatcaa acctgggtat
    53461 gagtggaagg tcgtggatgc cttctcaacc aacttccatc tgccaaaatc aactctggtc
    53521 atgttggttt ctgcctttgc aggccgtgaa ttagtcttag atgcctacca ccatgccatc
    53581 caagaacact accgcttctt cagttttggt gacgccatgt ttatttattg agaaagaatt
    53641 tctctaattc ttctaatacc aataaatcgc taagatatta tttcaaagaa catctacaat
    53701 tgaaactcta gctagctgta gaagacgcct agtacattga aattaaaatg cttcccccta
    53761 gcttcgaaaa tattgccata gattgcgttg actctccaaa ttgattcatc tatattttat
    53821 ttcagcttcc tatattttct tcgctgtttg taaatcaaaa tgcaagacac atgagtagca
    53881 ccatatttgt tactcttatc tgtcctctca agagactatt atgagttatt tcagaatcat
    53941 tcactacttt gaccctgact ctccttagtc tcaaaatcaa agacttatac tcttcaaaaa
    54001 tctcttcaaa ccgcgtcaac gtcaccttgg attatatatg tgactgactt cgtcagttct
    54061 atctacaacc tcaaagcagt actttgagca acctgcgact agttttctag tttgctcttt
    54121 gattttcatt gagtattaaa caaaaagtga acaaatctga attctaatgt acagaagact
    54181 aggcttgttc acttttttat agtcgctata agatgacctt atctatagct ttttatatat
    54241 aattatatat tcagacatac tattatcaat tttgtcgcag ggaggaatct gttaacgcac
    54301 ccattcacca ttatcattga ctctatagcc atctatactt gtattgaccg ctaactcacc
    54361 cgatgcattt acataatacc atttaccacc aacttggaac cattgattga ctttcataga
    54421 accgttgctg ttgaggtagt accatgaacc attaacttgt acccaacctg ttgccatgga
    54481 accatcagta ttataaaaat accacatacc attttcttgt ttccagtctg ttgttggagc
    54541 aactgcttta gctggttcta ctgctacatc tgttccttgg ttagatgtaa cagatacagg
    54601 atacgaagga atagatgatt gctcaggaac aacaactttt tcaggttctc tcgtccctct
    54661 ccttatacgt ctttttacca tctctttagt aatttgacga gaagtagttt cttcaattgt
    54721 tccatcacgt tcatctacag tatagattgt agtaagagta atttaccaat ttctcctact
    54781 tcttctactt cttgactttt atcaagagtt gggccatcga gatattctgt ttcgattgga
    54841 atttcttgga caagaacttg gggcttggtt ctttttttaa caactcttgt ttgagagtct
    54901 ttttttgact taaagtactc tcagttactt gtccactctt tccatctaca ttataagtta
    54961 tcgttgtaac tgttttccca ttctttccta gagtaatctc ttgctcctgt cctgcagaaa
    55021 ggtcattgtc tgcttcatat ttagtagcaa atggaacaag aacttcttca accttgcttt
    55081 tagctggaac tttgataact gtatccgtgg cttcttttct atcaacagta acctgttcgg
    55141 taacataacc agtctctgga ttaacatcgt aggtccttgt cgtagttaca tagccatcct
    55201 ctccatcaat tgtaacagga ttttcactac ggtcttttgt ttcatctttt tcataacgaa
    55261 ttcgcgtact tgaaattttc ttggttacta ccttaggttt agtcgctact tttacaataa
    55321 tatccccatt gtcagcgtca tcatactcta ttccctcttc tttatctcta gtatcatctc
    55381 tgacatattg aatcccatca gcagcatgaa caaaacttgt attcagattc ctcctaaaaa
    55441 taaagttagc ccgattaccg cagaaccaaa aatctttccg agtttacgta ttgcatagcg
    55501 cttattagta ttagattttg ccattacatc ctacttctag tatagcatct tttctatcaa
    55561 acgttaaaca atatacttta tatataaaat agacttagaa tgatatattg attattgaac
    55621 taacacttta actatatcgt aatcaatctc atatataaag gattgcagac atcttatcta
    55681 aatacatgct aatatattta gatacaaaca ttccaacttg ataattttca ctcatctttc
    55741 atcattcctt atacaactat gcagtataaa tagaatagtt ttctcatcag aatgagacta
    55801 ttttaatatt agataatttg atagaaaaaa catgaataaa attggttgaa tttaattccc
    55861 taactcgata gaggattcta ttttaaattt aacaacagct aggattacac tataaaaagt
    55921 acattaccac ctgttcggct ggagaatcta gtcgattagc tccctcttag ttacaagctt
    55981 caagcgattt tttaactaac actaaaccag attaaagaag gaactagaac atctgtcttg
    56041 tactaatcaa tatgctattt taaagtttca aataaacttg gaatgctaat tattatattt
    56101 acaataaata gttgacttcg atagaaacag aaaatagaat tcaacattct tccctactta
    56161 taccataata aataagatcc gcaagatagc cttttctctc tacaccatta acaatggttt
    56221 gtagatagga cattccagcc ttttccatga cacgacctga agctgggttg agactggcat
    56281 aacgtgctct gaccttttga aaacctgctt gagtaaaaca aaagtccaag atagctttca
    56341 aagtctctgt catcatacca tttccccagt aagccttgcc taacacatag ccaatttcac
    56401 agcttaaatc agcctcgtct atcttaacaa tgctgatatc tcctattact tgctctgggt
    56461 tttcttttag acaaatggcc catttataat agttgagatt agtataggaa gcaacccaat
    56521 tgcaaatcga gtttcgagtg atttcgacat caggatgggg atcccaggta acataggtca
    56581 gattctcagc ggatgaagcc caattttgaa acatggcttc tgcatcactc tccacaaatc
    56641 ttcttaaaat caaacgttct gtctgtaata tttgcgtacc gatagatttc atgatgctac
    56701 ctcacttcct tatttctata ctcgtagtaa aaaggctcaa ctcagtaaca gctagaaaac
    56761 gagtttgtct tctaatttct tgacgcagtt gctgcctggt ttgaaatgcg ctctagcaag
    56821 ctttttcaaa cctagtcatc gttgcagggg taagacgatg aaatcgaact cttcgagtta
    56881 ctgaatctgc ctcattttct tatttctaaa ctcggggttc aagatccccc agaccttctc
    56941 tcactttctt atttcaagat gagaggctga aaacctccag tggaggtttt tcttgctttt
    57001 taatttcagg gcaagaagct aaaaaggtcc cccggacctt tttactccca aaagtcatca
    57061 aatacggtga tgggtaagtg gcgtttgtgt tggcctttgt gccaccagtt ttcaatggtc
    57121 gcttgagctt ctgggctgat tgttttgcct tctaggtagt cgtcaatctc tgcgtaggtg
    57181 actccaagtg cgacttcgtc agctaggcct ggtttatctt cttctaggtc tgccgttggg
    57241 attttttcat aaagggctgg ctctgcgcca agtttctgca agagctgttt tccttggcgt
    57301 ttattgaggc ggtaaagagg gagaatatcc gcaccgccgt caccaaactt ggtaaagaaa
    57361 cctgtgatat tttccgcggc gtggtctgtt ccaatgaccg ctccgctatg ggaaccagca
    57421 agggcatact gagcaatcat acggcaacgt gccttgatat tccccttgtt gaagtctgaa
    57481 acaggactac ctgtcgcttc aactgcagct gtcatggcat cagctgattc cttgatattc
    57541 acaaccaagc tgacatctgg ctggatgaag gctagggctt tttgagcatc tgcttcatca
    57601 gcttgcactc cgtatggcag gcggacagcg ataaatttgt agctatcgtc tcccgtttca
    57661 gctcgcagtt cttccatagc taattgcgcc aaacgtcctg ccaaggttga gtcttgtccc
    57721 ccagaaatcc ctagtacaaa ggtttttagg aagggatgtt ttttcagata tctttttaag
    57781 aaatcaatag aacgacggat ttcttcctgg gcatcaatca ctggtttgac acccagctct
    57841 tggataatcg tttcttgcaa actcattctt cttctccttc accaagggct tccttgcgca
    57901 tcttatcaat caagtccatc ttatcttgcc atacatcacg cgccaaatcc actggatagt
    57961 gctgcggatt gagcacacgc ttatactcat cccacaactt gtcaaattcc ttacgggcat
    58021 aatcctgaat gtcagtcaaa ctaggcaagt tgtaaactaa tattccttct ttgaagatat
    58081 ccaccaagag aggaacggca tcaaaattac gaaccgtctt cttgatgtat gtataggtcg
    58141 gatggaacat cttgatttct gtcatgtcgc taatatccac accatcataa gtgatatagt
    58201 cgccttctga cttgcctttt tcacgactgg taatgcgcca cacctgcttc ttacctggcg
    58261 tagaaacttt ttcagcatta ttagacagct taatcgtatt gcgcatctga ccagtttcat
    58321 cttcgattgc aacaatcttg taaaccgccc caagagccgg ctggtcatag gctgtaatca
    58381 gcttggtacc cacaccccag acatcaatct tggccttttg catcttgagg ttaaggatgg
    58441 tattttcatc tagatcatta gaagcataaa tcttagcctc tgtaaatcca gcctcatcca
    58501 gttgctgacg gactttctta gaaatgtagg caatatcccc agagtcaatc cgcacaccca
    58561 taaagttaat ctgatcaccc agctcacgcg ccacctgaat ggcagctggt acaccgatgc
    58621 gaagggtgtc ataggtatcc acaagaaaga cacaattttt gtgggtcgca gcgtaagcct
    58681 tgaaagcttc atagtcattg ccataaacct gtaccaaggc atgggcatgg gttcccaaaa
    58741 caggaatgtc aaagagctta cccgcacgca cgttgctagt tccattggcg ccaccaatca
    58801 cagctgcgcg tgttccccag atggccgcat ccatttcttg agcccgacgt gtcccaaact
    58861 ccatcaaggg ttcatcttcg ataaccgaac gaatacgagc tgccttcgtc gccaccaagg
    58921 tctggtagtt gacgatgttc aaaagagccg tttcgaccaa ctgacattgg gctagaggtc
    58981 cttccacctg cacaatcggt tcattagcaa aaaccaaatc cccttcttgg gcagaacgaa
    59041 cggtcaactc caacttgaaa ttgcgaaggt aatccaagaa cgccccatga taaccaagcg
    59101 actccaaata ggctatatca ctatctgaaa aacgcaagtc ttcaagatag ttcacaattc
    59161 tttccaaacc tgcaaaaacc gcatagccgt tcttaaaagg ctgttggcgg aaatacacct
    59221 caaagaccgc cttcttattg tgaatccctt ggtcaaagta aacctgcatc atgttgatct
    59281 ggtacaagtc cgtgtgcaat gtcaaactat catctggata catacttttc ctacttcctt
    59341 agctagaaac ccatgaaaat tttcaagaac tttcatgtat tccaataaat tagtactatt
    59401 atatcacatt ttagctggat tgagaaaaga gtaacaagct attctccact ctccaattca
    59461 tccatatctt gttcaaattt tttctgagcc cattcgccat agctcttaag accaagattg
    59521 ccaataaaga tccacggaag gtaaatgata taagtaatga cccaagcaga caggtattta
    59581 aaattcaaag gattgtgctg ataaatttct atgttgaatt gataattctg caacatcaaa
    59641 agagccgtaa tagccaaggt taggaaaaaa caacccaaaa tcgtaaaatg aaaacgacta
    59701 tagtaggtca ctcccagata acgggcacga ttgaaaaagt aaaatgtccc tatgatgata
    59761 acgattagca gcatattaga attaaaaagg cttggtgcta atactgaaat gatataagat
    59821 aggagcgaca aagcgatgca gatatagaaa ctttcagagc ccgctttatt gaacagttgt
    59881 tcttctcttt cgtctagtaa ttgataataa taaaatctat ttttcatctt cttcctccca
    59941 aaatagttgg tctagggttt tccctaaaca tctgcaaatg gactggcaga gcgagagact
    60001 gggattgtat ttccccgctt ctatcaaacc aatagtctgg cgcgtcaccc cgacagcctc
    60061 tgccagttga ccttgtgtta aatcacgctc tacccgagct aattttaatt ttaaattttt
    60121 agccaccttc gtcctcctta tagttttaat actcatctac tcttaaaaaa tccaaaacca
    60181 acacaagcta tcagctattt attataaccc cattaatttg cactccagta ttatcttcag
    60241 ccgaaaatca gtattttagg ttgtttgaaa taaacttcct agtttactct tttattttta
    60301 tttagtatta gctttagtag gatcttttaa acgagttttt attgcttata tttcttgttt
    60361 agtttagttg gtttcatatc actattatat aatgcttttg gaaatgagcc tagtataagt
    60421 caaaaacgtg ttgaatagtg aaagcaggag cataccaaga tgactgattt ttttattgta
    60481 ttttaggtat gcaaaataat actaaatgaa actaaaatga atacttcttg cttttcttga
    60541 gagtgaaaaa gtacaataaa atgattgtag tgattagcac aagatactga ctaatagaca
    60601 tcgtatttga agccacaaat acaggtaaag aataaaaaag gaagaagttc aattgctttg
    60661 ataaacaaat cattactagt attcatcatc atcgtattta atatattaga gataaagagt
    60721 agtaaagcta ctaaaatacc aaataccaag ccacttttca atttgtataa atagaaaatg
    60781 taagataata gaaaataaaa caggactaac aaaattgtat tgactacaat agctactata
    60841 aaatttaatc ctaaatcacc tggaataccc aatttactta ctatgactag taacacaatg
    60901 ccattcaaag cataaataat ggaaactgag atagcatata gaaaattaga caagacgtaa
    60961 atcatccgat tcttctgttt atttaatttc atgattataa ccttccttta ttttgaacga
    61021 tttaggtaaa tatctttaag cgtctctttt ttagtttcaa aatcaactac tttaatagag
    61081 ttttcgttaa aaaatttaaa aagctcacta ttttgaatat tcccagacat agtaattctc
    61141 aatccctctt cctaaacaat atcccaaaat tcttgtttgg taatgaaaat gtctctatct
    61201 gtagctgatg aaaaagctat ctcaaacaag aaattatgac tatcttttcc tactttttga
    61261 aatgtcaaaa gcccgttctc caagaaaaga actctctcac aaatttcttc aatgtcttct
    61321 aatttatgac tcgatattaa aattcccaca ttttcatgta aagctaattt ttttagaacc
    61381 gctaaaacta tttgtgatga ttcaatatct aaaccattag tcggttcatc taaaatcaat
    61441 atatcaggtt ccgtaacgag agttagaagc aaagctaatt tttgttttgt acccaaagaa
    61501 taggtcttta cttttttatt aatagactga gtcaaatcta actcttggat caaacatcta
    61561 aatctttctt gattgtagtc aacaccatat aaatttgaca aatattttaa attctctaaa
    61621 cctgttttag ataaaaataa ttttggttct tcgattaaat acccaacatt atcactgctt
    61681 ataatattac ctgaagtcgg ttgattattc tgaacaagaa ttttcatcaa cgtactctta
    61741 ccaactccat ttctccctgc tagaccaaca atttcaccct tgttaagtgc aaaatttata
    61801 tctttgagaa tgattgaatg accataatgc ttacttacat tttttattcc tccattaata
    61861 ttattggttt tctctttgat tctcattaat tttaaaaagt tgcgcctctt tttaacaata
    61921 ttatatcata tatctaactt aatgcaatat ataaatgtca ttttgtgaaa ttttattaac
    61981 aaaaaactct ctacaacaaa ataatagaga gttttctgct tattaatttt tttcaaaata
    62041 tctaagacat cacttctttg tttaatttga taggctttga tacctgagct ccgactttat
    62101 cacttaaaaa ataaaaaaga cagctaatct cttgcgcatc aagggatttc gccattcttt
    62161 aatctcgttt aagtgttgta tatggagctt tgcataattt tttaaaacta aacaactaca
    62221 ttaagcacga actgtgacgc tggttccatc ttccttataa agattgataa gcccctcttt
    62281 aagagctcga accatgtctc cagcttgaac aggttgtggg actttaatag tcaatagttc
    62341 cattggattt ggagcgcggt cgattttatt gcctttggc
//
LOCUS       DAVBOG010000006        60620 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.006, whole genome shotgun sequence.
ACCESSION   DAVBOG010000006 DAVBOG010000000
VERSION     DAVBOG010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 60620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 60620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..60620
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.006"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            127..408
                     /locus_tag="VQ865_000357"
                     /pseudo
     CDS             127..408
                     /locus_tag="VQ865_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            complement(533..736)
                     /locus_tag="VQ865_000358"
     CDS             complement(533..736)
                     /locus_tag="VQ865_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134778.1"
                     /translation="MIKLYSPYAFLSKYLGAILLSFFCYYAKEIGCNNLTLSVWNDNE
                     GALRFYQRQGMKPQETTMEMIID"
     gene            complement(729..1811)
                     /locus_tag="VQ865_000359"
     CDS             complement(729..1811)
                     /locus_tag="VQ865_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3134779.1"
                     /translation="MSKLQQILTYLESEKLDVAVVSDPVTINYLTGFYSDPHERQMFL
                     FVLADQEPLLFVPALEVERASSTVSFPVVGYVDSENPWQKIKHALPQLDFKRVAVEFD
                     NLILTKYHGLKTVFETAEFDNLTPRIQRMRLIKSADEVQKMMVAGLYADKAVHVGFDN
                     ISLDKTETDIIAQIDFAMKREGYEMSFDTMVLTGDNAANPHGIPAANKVENDALLLFD
                     LGVLVNGYASDMTRTVAVGKPDQFKKDIYNLTLEAQQAALDFIKPGVTAHEVDRAARE
                     VIEKAGYGEYFNHRLGHGIGMDVHEFPSIMEGNDMVIEEGMCFSVEPGIYIPGKVGVR
                     IEDCGVVTKDGFDLFTSTSKDLLYFD"
     gene            complement(1937..2719)
                     /locus_tag="VQ865_000360"
     CDS             complement(1937..2719)
                     /locus_tag="VQ865_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HET3134780.1"
                     /translation="MVYTSLSSKDGNYPYQLNIAHLYGNLMNTYGDNGNILMLKYVAE
                     KLGAHVTVDIVSLHDDFDENHYDIAFFGGGQDFEQSIIADDLPAKKESIDNYIQNDGV
                     VLAICGGFQLLGQYYVEASGKRIEGLGVMGHYTLNQTNNRFIGDIKIHNEDFDETYYG
                     FENHQGRTFLSDDQKPLGQVVYGNGNNEEKVGEGVHYKNVFGSYFHGPILSRNANLAY
                     RLVTTALKKKYGQDIQLPAYEDILSQEIAEEYSDVKSKADFS"
     gene            complement(2719..4062)
                     /locus_tag="VQ865_000361"
     CDS             complement(2719..4062)
                     /locus_tag="VQ865_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HET3134781.1"
                     /translation="MNLKTTLGLLAGRSSHFVLSRLGRGSTLPGKVALQFDKDILQNL
                     AKNYEIVVVTGTNGKTLTTALTVGILKEVYGQVLTNPSGANMITGIATTFLTAKSSKT
                     GKNIAVLEIDEASLSRICDYIQPSLFVITNIFRDQMDRFGEIYTTYNMILDAIRKVPT
                     ATVLLNGDSPLFYKPTIPNPIEYFGFDLEKGPAQLAHYNTEGILCPDCQGILKYEHNT
                     YANLGAYICEGCGCKRPDLDYRLTKLVELTNNRSRFVIDGQEYGIQIGGLYNIYNALA
                     AVAIARFLGADSQLIKQGFDKSRAVFGRQETFHIGDKKCTLVLIKNPVGATQAIEMIK
                     LAPYPFSLSVLLNANYADGIDTSWIWDADFEQITDMDIPEINAGGVRHSEIARRLRVT
                     GYPAEKITETSNLEQVLKTIENQDCKHAYILATYTAMLEFRELLASRQIVRKEMN"
     gene            complement(4161..5477)
                     /locus_tag="VQ865_000362"
     CDS             complement(4161..5477)
                     /locus_tag="VQ865_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HET3134782.1"
                     /translation="MLTYDLIVIGFGKAGKTLAGKLASAGKKVALVERSKAMYGGTCI
                     NIGCIPTKTLLVAAEKDLSFEEVIATKNTITGRLNGKNYTTVAGTGVNIFDAEAHFLS
                     NKVIEIQAGDEKQELTAETIVINTGAVSNVLPIPGLATSKNVFDSTGIQSLDKLPEKL
                     GVLGGGNIGLEFAGLYNKLGSKVTVLDALDTFLPRAEPSIAALAKQYLEEDGIELLQN
                     IHTTEIKNDGDQVLVVTEDETYRFDALLYATGRKPNVEPLQLENTDIELTERGAIKVD
                     KHCQTNVPGVFAVGDVNGGLQFTYISLDDFRVVYSYLAGDGSYTLEDRLNVPNTMFIT
                     PALSQVGLTESQAADLKLPYAVKEIPVAAMPRGHVNGDLRGAFKAVVNTETKEILGAS
                     IFSEGSQEIINIITVAMDNKIPYTYFTKQIFTHPTLAENLNDLFAI"
     gene            5671..6897
                     /locus_tag="VQ865_000363"
     CDS             5671..6897
                     /locus_tag="VQ865_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000841575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OFA family MFS transporter"
                     /protein_id="HET3134783.1"
                     /translation="MKSNRYIIAFAGVILHLMLGSTYAWSVYRNPIIEKTGWDQASVA
                     FAFSLAIFCLGLSAAFMGRLVEKFGPKVMGSLSAFLYAGGNILTGFAIDRQELWLLYL
                     AYGILGGLGLGAGYITPVSTIIKWFPDKRGLATGLAIMGFGFASLLTSPIAQHLIAGV
                     GLVETFYILGASYFIIMLLASQFIKRPNEQELAILSSSGKEKTASLTQGMAANQALKS
                     NRFYMLWIIFFINIACGLGLISAASPMAQEMAGLSTSHAAVMVGVLGIFNGFGRLLWA
                     SLSDYIGRPLTFSILLLVNLFFSLSLWLFTDSVLFVVAMSILMTCYGAGFSLIPAYLS
                     DIFGTKELAALHGYILTAWAMAGLAGPILLAETYKMAHSYTQTLFVFLILYSIALALS
                     YYLGRSIKKESQKPLT"
     gene            7096..8670
                     /locus_tag="VQ865_000364"
     CDS             7096..8670
                     /locus_tag="VQ865_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3134784.1"
                     /translation="MKFNELNLSADLLAEIEKAGFVEASPIQEQTIPLALEGKDVIGQ
                     AQTGTGKTAAFGLPTLEKIRTEEATIQALVIAPTRELAVQSQEELFRFGRSKGVKVRS
                     VYGGSSIEKQIKALKSGAHIVVGTPGRLLDLIKRKALKLQNIETLILDEADEMLNMGF
                     LEDIEAIISRVPENRQTLLFSATMPDAIKRIGVQFMKAPEHVKIAAKELTTELVDQYY
                     IRVKEQEKFDTMTRLMDVAQPELAIVFGRTKRRVDELTRGLKIRGFRAEGIHGDLDQN
                     KRLRVLRDFKNGNLDVLVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KSGQSITFVAPNEMGYLQIIENLTKKRMKGLKPASVEESFQSKKQVALKKIERDFADE
                     TIRANFEKFGKDARKLAAEFTPEELAMYILSLTVQDPDSLPEVEIAREKPLPFKPSGN
                     GFGGKAKGGRGGRRGDDRRERDRRGNGRRDEFKKGSRGNDRFDKEKRYRKDNKKPRNT
                     LSEKQTGFVIRNKGDK"
     gene            8935..9723
                     /gene="codY"
                     /locus_tag="VQ865_000365"
     CDS             8935..9723
                     /gene="codY"
                     /locus_tag="VQ865_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HET3134785.1"
                     /translation="MAHLLEKTRKITSILKRSEEQLQDELPYNAITRQLADIIHCNAC
                     IINSKGRLLGYFMRYKTNTDRVEQFFQTKIFPDDYVQGANMIYETEANLPVEHDMSIF
                     PVESRDDFPDGLTTIAPIHVSGIRLGSLIIWRNDKKFEDEDLVLVEIASTVVGIQLLN
                     FQREEDEKNIRRRTAVTMAVNTLSYSELRAVSAILGELNGNEGKLTASVIADRIGITR
                     SVIVNALRKLESAGIIESRSLGMKGTYLKVLISDIFEEVKKRDY"
     gene            9723..10298
                     /locus_tag="VQ865_000366"
     CDS             9723..10298
                     /locus_tag="VQ865_000366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3134786.1"
                     /translation="MTKALISIDYTEDFVADSGKLTAGAPAQAISDAISKVTRLAFER
                     GDYIFFTIDAHEENDCFHPESKLFPPHNLIGTSGRNLYGDLGNFYQEHGSDSRVFWMD
                     KRHYSAFSGTDLDIRLRERRVSTVILTGVLTDICVLHTAIDAYNLGYDIEIVKPAVAS
                     IWPENHQFALGHFKNTLGAKLVDENLNELSE"
     gene            10380..10465
                     /locus_tag="VQ865_000367"
     tRNA            10380..10465
                     /locus_tag="VQ865_000367"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10414..10416,aa:Leu,seq:aag)
     gene            10748..11878
                     /gene="ugpC"
                     /locus_tag="VQ865_000368"
     CDS             10748..11878
                     /gene="ugpC"
                     /locus_tag="VQ865_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HET3134787.1"
                     /translation="MVELNLKNIYKKYPNSEHYSVEDFNLNIKDKEFIVFVGPSGCGK
                     STTLRMIAGLEDITEGTASIDGVVVNDVAPKDRDIAMVFQNYALYPHMTVYDNMAFGL
                     KLRKYSKEDINKRVQEAAEILGLKEFLERKPADLSGGQRQRVAMGRAIVRDAKVFLMD
                     EPLSNLDAKLRVSMRAEIAKIHRRIGATTIYVTHDQTEAMTLADRIVIMSATKNPAGT
                     GTIGRVEQIGTPQEVYKNPVNKFVAGFIGSPAMNFINVKLVGSEIVSDGFRLKVPEGA
                     LKVLREKGYEGKELIFGIRPEDVNAEPAFLETFPDCVVKATISVSELLGSESHLYCQV
                     GKDEFVAKVDARDYLQTGATVELGFDLNKAHFFDVETEKTIY"
     gene            12379..13137
                     /locus_tag="VQ865_000369"
     CDS             12379..13137
                     /locus_tag="VQ865_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001848902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3134788.1"
                     /translation="MSEAGHKFLAKLGKKRLRPGGKRATDWLIAEGGFSKEKRILEVA
                     CNRGTTAIELAQRFGCKITAVDMDAQALEVAKKSAGTAGVAHLISFERANAMKLPYQD
                     ASFDIVINEAMLTMQADQAKKKCVMEYLRVLKPGGLLLTHDVLLKEAKESIRQELSQA
                     IHVNVGPLTQDGWEQVMIESGYCDVKALTGEMTLMKLSGMIYDEGLLGTLKICVNACK
                     KENRKQFLTMYKMFAKNKQKLGFIAMASYKSSKR"
     gene            13224..13736
                     /locus_tag="VQ865_000370"
     CDS             13224..13736
                     /locus_tag="VQ865_000370"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HET3134789.1"
                     /translation="MNLKDYIATIENYPKEGITFRDISPLMADGNAYSYAVREIVQYA
                     TDKKVDMIVGPEARGFIVGCPVAFELGIGFAPVRKPGKLPREVISADYEKEYGVDTLT
                     MHADAIKPGQRVLIVDDLLATGGTVKATIEMIEKLGGVMAGCAFLVELDELNGREKIG
                     DYDYKVLMHY"
     gene            13918..14862
                     /locus_tag="VQ865_000371"
     CDS             13918..14862
                     /locus_tag="VQ865_000371"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HET3134790.1"
                     /translation="MPIRIDKKLPAVEILRTENIFVMDDQRAAHQDIRPLKILILNLM
                     PQKMVTETQLLRHLANTPLQLDIDFLYMESHRSKTTRSEHMETFYKTFPEVKDEYFDG
                     MIITGAPVEHLPFEEVDYWEEFRQMLEWSKTHVYSTLHICWGAQAGLYLRYGVEKYQM
                     DSKLSGIYPQDTLKEGHLLFRGFDDSYVSPHSRHTEISKEEVLNKTNLEILSEGPQVG
                     VSILASRDLREIYSFGHLEYDRDTLAKEYFRDRDAGFDPHIPENYFKDDDVNQVPCLC
                     WSSSAALFFSNWVNHAVYQETPFDWRKIEDDASAYGYL"
     gene            14871..15548
                     /locus_tag="VQ865_000372"
     CDS             14871..15548
                     /locus_tag="VQ865_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain-containing protein"
                     /protein_id="HET3134791.1"
                     /translation="MTYLDAFKSGILVLPSALLLHFKELFPSSDDFLVWQFFYLQNTT
                     GLEEMSPSQIAERIGKEISDVNQSISNLTERGLLQYRTIELNGEIELLFDASLALERL
                     DDLFGAVHSSSDQLTPQNQLKDLVETFQQELGRLLTPFEIEDLTKTLKEDGTSADLIK
                     EALREAVLNGKPNWKYIQAILRNWRHEGIKSVAQIEAKRAEREASNPQLTQVSADFIN
                     AMDLWKD"
     gene            15646..16404
                     /locus_tag="VQ865_000373"
     CDS             15646..16404
                     /locus_tag="VQ865_000373"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000087908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HET3134792.1"
                     /translation="MSRKPFIAGNWKMNKNPEEAKAFVEAVASKLPSSDLVEAGIAAP
                     ALDLTTVLAVAKGSNLKVAAQNCYFENAGAFTGETSPQVLKEIGTDYVVIGHSERRDY
                     FHETDEDINKKAKAIFANGMLPIICCGESLETYEAGKAAEFVGAQVSAALAGLTAEQV
                     AASVIAYEPIWAIGTGKSASQDDAQKMCKVVRDVVAADFGQEVADKVRVQYGGSVKPE
                     NVASYMACPDVDGALVGGASLEAESFLALLDFVK"
     gene            16442..17947
                     /gene="lytC"
                     /locus_tag="VQ865_000374"
     CDS             16442..17947
                     /gene="lytC"
                     /locus_tag="VQ865_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_078138769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase LytC"
                     /protein_id="HET3134793.1"
                     /translation="MSVTFFIGEERLKTKIGLASICLLGLATSHVAANETEVAKTSQD
                     TTTASSSSEQNQSSNKTQTSTEVQTNAAAHWDGDYYVKDDGSKAQSEWIFDNYYKAWF
                     YINSDGRYSQNEWHGNYYLKSGGYMAQNEWIYDSNYKSWFYLKSDGAYAHQEWQLIGN
                     KWYYFKKWGYMAKSQWQGSYFLNGQGAMMQNEWLYDPAYSAYFYLKSDGTYANQEWQK
                     VGGKWYYFKKWGYMARNEWQGNYYLTGSGAMATDEVIMDGARYIFAASGELKEKKDLN
                     VGWVHRDGKRYFFNNREEQVGTEHAKKVIDISEHNGRINDWKKVIDENEVDGVIVRLG
                     YSGKEDKELAHNIKELNRLGIPYGVYLYTYAENETDAENDAKQTIELIKKYNMNLSYP
                     IYYDVENWEYVNKSKRAPSDTDTWVKIINKYMDTMKQAGYQNVYVYSYRSLLQTRLKH
                     PDILKHVNWVAAYTNALEWENPYYSGEKGWQYTSSEYMKGIQGRVDVSVWY"
     gene            18444..18962
                     /locus_tag="VQ865_000375"
     CDS             18444..18962
                     /locus_tag="VQ865_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HET3134794.1"
                     /translation="MVELKKEAVKDVTSLTKAAPVALAKTKEVLNQAVADLYVAHVAL
                     HQVHWYMHGRGFLVWHPKMDEYMEALDGQLDEISERLITLGGSPFSTLTEFLQNSEIE
                     EEASEYRNVEESLERVLVIYRYLSELFQKGLDVTDEEGDDVTNGIFAGAKTETDKTIW
                     MLAAELGQAPGL"
     gene            19092..19598
                     /locus_tag="VQ865_000376"
     CDS             19092..19598
                     /locus_tag="VQ865_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HET3134795.1"
                     /translation="MTKKIVAIWAQDEEGVIGKENRLPWHLPAELQHFKETTLNHAIL
                     MGRVTFDGMGRRLLPKRETLILTRNPEEKIDGVATFQDVQSVLDWYQAQEKNLYIIGG
                     KQIFQAFEPYLDEVIVTHIHARVEGDTYFPEELDLSLFETVSSKFYAKDEKNPYDFTI
                     QYRKRKEL"
     gene            19800..21032
                     /gene="clpX"
                     /locus_tag="VQ865_000377"
     CDS             19800..21032
                     /gene="clpX"
                     /locus_tag="VQ865_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002874765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HET3134796.1"
                     /translation="MSTNRKNDMMVYCSFCGKNQEEVQKIIAGNNAFICNECVELAQE
                     IIREELVEEVLADLSEVPKPIELLHILNHYVIGQDRAKRALAVAVYNHYKRINFHDTR
                     EESEDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVEN
                     ILLKLLQVADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGT
                     VASVPPQGGRKHPQQEMIQVDTKNILFIVGGAFDGIEEIVKQRLGEKVIGFGQNNKAI
                     DENSSYMQEIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRILKEPRNALVKQYQ
                     TLLSYDDVELEFDDEALQEIANKAIERKTGARGLRSIIEETMLDVMFEVPSQENVKLV
                     RITKETVDGTDKPILETA"
     gene            21041..21628
                     /locus_tag="VQ865_000378"
     CDS             21041..21628
                     /locus_tag="VQ865_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002915299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HET3134797.1"
                     /translation="MELNIHNAEILLSAANKSHYPQDELPEIALAGRSNVGKSSFINT
                     MLNRKNLARTSGKPGKTQLLNFFNIDDKMRFVDVPGYGYARVSKKEREKWGCMIEEYL
                     TTRENLRAVVSLVDLRHDPSADDVQMYEFLKYYEIPVIIVATKADKIPRGKWNKHESA
                     IKKKLNFDPSDDFILFSSVSKAGMDEAWDAILEKL"
     gene            21639..22019
                     /locus_tag="VQ865_000379"
     CDS             21639..22019
                     /locus_tag="VQ865_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HET3134798.1"
                     /translation="MAKTIHTDKAPKAIGPYVQGKIVGNLLFASGQVPLSPETGEIVG
                     ENIQEQTEQVLKNIGAILAEAGTDFDHVVKTTCFLSDMNDFVPFNEVYQTAFKEEFPA
                     RSAVEVARLPRDVKVEIEVIAEIG"
     gene            22071..22961
                     /gene="rapZ"
                     /locus_tag="VQ865_000380"
     CDS             22071..22961
                     /gene="rapZ"
                     /locus_tag="VQ865_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HET3134799.1"
                     /translation="MTKKQLHLVIVTGMSGAGKTVAIQSFEDLGYFTIDNMPPALLPK
                     FLQLVEIKEDNPKLALVVDMRSRSFFSEIQAVLDELENQDGLDFKILFLDAADKELVA
                     RYKETRRSHPLAADGRILDGIKLERELLAPLKNMSQNVVDTTELTPRELRKTLAEQFS
                     DQEQAQSFRIEVMSFGFKYGIPIDADLVFDVRFLPNPYYLPELRNQTGVDEPVYDYVM
                     NHPESEDFYQHLLALIEPILPSYQKEGKSVLTIAMGCTGGQHRSVAFAKRLAQDLSKN
                     WSVNEGHRDKDRRKETVNRS"
     gene            22958..23935
                     /locus_tag="VQ865_000381"
     CDS             22958..23935
                     /locus_tag="VQ865_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HET3134800.1"
                     /translation="MRKPKITVIGGGTGIPVILKSLREKDVEIAAIVTVADDGGSSGE
                     LRKNMQQLTPPGDLRNVLVAMSDMPKFYEKVFQYRFSEDAGAFAGHPLGNLIIAGLSE
                     MQGSTYNAMQLLSKFFHTTGKIYPSSDHPLTLHAVFQDGTEVVGESHIVDHRGIIDNV
                     YVTNALNDDTPLASRRVVQTILESDMIVLGPGSLFTSILPNIVIKEIGRALLETKAEI
                     AYVCNIMTQRGETEHFTDSDHVEVLHRHLGRPFIDTVLVNIEKVPQKYMNSNRFDEYL
                     VQVEHDFVGLCKQVSRVISSNFLRLENGGAFHDGDLIVDELMRIIQVKK"
     gene            23932..24843
                     /gene="whiA"
                     /locus_tag="VQ865_000382"
     CDS             23932..24843
                     /gene="whiA"
                     /locus_tag="VQ865_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HET3134801.1"
                     /translation="MSFTVAVKEEILGQHHLSRHELSAIIKMSGSIGLSTSGLTLSVV
                     TENAKLARHLYESFLHFYEIKSEIRHHQRSNLRKNRVYTVFTDEKVQDLLSDLHLADS
                     FFGLETGIDEAILSDEEAGRAYLCGAFLANGSIRDPESGKYQLEISSVYLDHAQGIAS
                     LLQQFLLDAKVLERKKGAVTYLQRAEDIMDFLIVIGAMQARDDFERVKILRETRNDLN
                     RANNAETANIARTVSASMKTINNISKIKDIMGLENLPVDLQEVAQLRIQHPDYSIQQL
                     ADSLSTPLTKSGVNHRLRKINKIADEL"
     gene            complement(24877..25845)
                     /locus_tag="VQ865_000383"
     CDS             complement(24877..25845)
                     /locus_tag="VQ865_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3134802.1"
                     /translation="MSQLYDITIVGGGPVGLFAAFYAHLRQAKVQIIDSLPQLGGQPA
                     ILYPEKEILDVPGFPNLTGEELTNRLIEQLNGFDTPIHLNETVLEIDKQEEEFAITTS
                     KGSHLTKTVIIAMGGGAFKPRPLELEGVEGYENIHYHVSNIQQYAGKKVTILGGGDSA
                     VDWALAFEKIAPTTLVHRRDNFRALEHSVQALQESSVTIKTPFAPSQLLGNGKTLDKL
                     EITKVKSDETETIDLDHLFVNYGFKSSVGNLKNWGLDLNRHKIIVNSKQESSQAGIYA
                     IGDCCYYDGKIDLIATGLGEAPTAVNNAINYIDPEQKVQPKHSTSL"
     gene            25981..26838
                     /locus_tag="VQ865_000384"
     CDS             25981..26838
                     /locus_tag="VQ865_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001867651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HET3134803.1"
                     /translation="MNFQQLSNLQYWTSLFASPWTIAINLIDILIVAYILYHFTKAIA
                     GTKIMILVRGVLVFILAQILANMIGLTTISWLINQIITYGVIAAVVIFSPEIRTGLER
                     LGRATDFFSNAPISAEEQMIRAFVKSVEYMSPRKIGALVAIQRVRTLQEYISTGIPLD
                     AKISAELLINIFIPNTPLHDGAVIIKEERIAVTSAYLPLTKNTGISKEFGTRHRAAIG
                     LSEVSDALTFVVSEETGGISITYNGRFKHNLTLDEFETELREILLPKEEVGLSFKERL
                     LGGWKHEKK"
     gene            26825..27604
                     /locus_tag="VQ865_000385"
     CDS             26825..27604
                     /locus_tag="VQ865_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbR-like domain-containing protein"
                     /protein_id="HET3134804.1"
                     /translation="MKKNSLYIISSLFFACVLFVYATATNFQNSTSARQVKTETYTNT
                     VTNVPIDIRYNSDKYFISGFASEVSVVLTGANRLSLASEMQESTRKFKVTADLTDAGV
                     GTIEVPLSIEDLPNGLTAVATPQKITVKIGKKAQKDKVKIVPEIDPSQIDSRVQIENV
                     MVSDKEVSITSDQETLDRIDKIIAVLPTSERITGNYSGSVPLQAIDRNGVVLPAVITP
                     FDTIMKVTTKPVAPSSSTSNSSTSSSSETSSSTKATSSKTN"
     gene            27628..28980
                     /locus_tag="VQ865_000386"
     CDS             27628..28980
                     /locus_tag="VQ865_000386"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HET3134805.1"
                     /translation="MGKYFGTDGVRGEANLELTPELAFKLGRFGGYVLSQHETEAPKV
                     FVGRDTRISGEMLESALVAGLLSVGIHVYKLGVLATPAVAYLVETEGASAGVMISASH
                     NPALDNGIKFFGGDGFKLDDEKEAEIEALLDAEEDTLPRPSAEGLGILVDYPEGLRKY
                     EGYLVSTGTPLDGMKVALDTANGAASTSARQIFADLGAQLTVIGETPDGLNINLNVGS
                     THPEALQEVVKESGSAIGLAFDGDSDRLIAVDENGDIVDGDKIMYIIGKYLSEKGQLA
                     QNTIVTTVMSNLGFHKALNREGINKAVTAVGDRYVVEEMRKSGYNLGGEQSGHVILMD
                     YNTTGDGQLSAVQLTKIMKETGKSLSELAAEVTIYPQKLVNIRVENVMKEKAMEVPAI
                     KAIIEKMEEEMAGNGRILVRPSGTEPLLRVMAEAPTTEEVDYYVDTITDVVRAEIGID
                     "
     gene            29054..29428
                     /locus_tag="VQ865_000387"
     CDS             29054..29428
                     /locus_tag="VQ865_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HET3134806.1"
                     /translation="MNLKREQEFVSQYHFDARNFEWENENGAPETKVDVNFQLLQHDQ
                     ENQVTSLIVILSFMIVFDKFVISGTISQVNHIDGRIVNEPNELNQEEVETLARPCLNM
                     LNRLTYEVTEIALDLPGINLEF"
     gene            29430..30278
                     /locus_tag="VQ865_000388"
     CDS             29430..30278
                     /locus_tag="VQ865_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3134807.1"
                     /translation="MKLAVFTDSSAYLSAETLQREDLFVLDIPVNIDGEEYVEGINLS
                     AEEFYQKMAQASELPKTSQPSIAKLDEILTSLKEQGYTHALGLFLSSGISGFYQNIQY
                     MVDDYEGLTIAFPDTLITSAPLGIMVESVFNWRDQGDDFASIQDKLAIQISRTSAFIM
                     VDDLDHLVKGGRLSNGAAILGNLLSIKPILYFNDQGVIEVYEKVRTEKKATKRLIEII
                     KETTASGQYRVIVIHGNAPEKAEELRQHLLDFGLGSDVSLATFGSVIGTHLGAGSIAL
                     GYIPVI"
     gene            30555..31322
                     /locus_tag="VQ865_000389"
     CDS             30555..31322
                     /locus_tag="VQ865_000389"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HET3134808.1"
                     /translation="MSIRVIIAGFKGKMGQAACQMVLTDPDLDLVAVLDPFESESEWQ
                     GIPVFKDKADLACFEADVWVDFTTPAVAYENTRFALENGFAPVVGTTGFTSEEIAELK
                     EFSRTQDLGGLIAPNFALGAVLLMQFATQAAKYFPNVEIIELHHDKKKDAPSGTAIKT
                     AELMAEIRESIQQGAADEEELIAGARGADFDGMRIHSVRLPGLVAHQEVIFGNQGEGL
                     TLRHDSYDRISFMTGVNLGIKEVVKRHELVYGLEHLL"
     gene            31334..32518
                     /locus_tag="VQ865_000390"
     CDS             31334..32518
                     /locus_tag="VQ865_000390"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HET3134809.1"
                     /translation="MPSEFQKALPVLEKIKEAGFEAYFVGGSVRDALLHSPIHDVDIA
                     TSSYPEETKQIFPRTADIGIEHGTVLVLDGDEEYEVTTFRTEDVYVDYRRPSAVSFVR
                     SLEEDLKRRDFTVNAFALDETGEIVDLFHGLEDLEKQVLRAVGVASERFNEDALRIMR
                     GFRFQASLGFALEPETFKAMKTLTPLLENISVERTFVEFDKLLLAPFWRRGLASMIES
                     QAYDYLPDMASSQDKLNRLFDLETDFTFESSEQAWAALLWALEIENAQSFLKSWKTSR
                     QFAKQVQDLLIILALRENGELSKRDCYRFDIDLLLQAENLRQAQGKEVNPQAITEKYQ
                     SLTIHDKKEIQINGGILIKEYGYQPGPDLGEILTEIEFAIVDGELENNREAIHAYLRE
                     KK"
     gene            32515..34386
                     /locus_tag="VQ865_000391"
     CDS             32515..34386
                     /locus_tag="VQ865_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001279112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3134810.1"
                     /translation="MSDFIVEKLSKSVGDKTVFRDISFIIHDLDRIGLIGVNGTGKTT
                     LLDVLSGVSGFDGDVSPFSAKNDYQIGYLTQDPDFDDRKTVLDTILSSELKEIQLIRE
                     YELIMLDYSEDKQARLERVMAEMDSLQAWEIESQVKTVLSKLGIQDLSTPVGELSGGL
                     RRRVQLAQVLLGNHDLLLLDEPTNHLDIAIIEWLTLFLKNSKKTVLFITHDRYFLDAL
                     STRIFELERAGLTEYQGNYQDYVRLKAEQDERDAALLHKKEQLYKQELVWMRRQPQAR
                     ATKQQARINRFHDLKKEVSGSSAETDLTMNFETSRIGKKVIEFQAVSFAYENKPILQD
                     FNLLVQAKDRIGIVGDNGVGKSTLLNLIAGSLEPTAGQVVIGETVRIAYFSQQIEGLD
                     ESKRVINYLQEVAEEVKTSGGSTTSIAELLEQFLFPRSTHGTLIEKLSGGEKKRLYLL
                     KLLLEKPNVLLLDEPTNDLDIATLTVLENFLQGFAGPVLTVSHDRYFLDKVATKILAF
                     EDGKIRPFFGHYTDYLDEKAFETDMANQVQKAEKEKVVKVREDKKRMTYQEKQEWASI
                     EGDIETLEKRIAAIEEEMQANGSDFGKLATLQKELDEKNEALLEKYERYEYLSEFDS"
     gene            complement(34529..35713)
                     /gene="mntE"
                     /locus_tag="VQ865_000392"
     CDS             complement(34529..35713)
                     /gene="mntE"
                     /locus_tag="VQ865_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family manganese efflux transporter MntE"
                     /protein_id="HET3134811.1"
                     /translation="MKQSISNLKLAERGAIISISTYLILSAAKLATGHLLHSSSLVAD
                     GFNNVSDIIGNVALLIGIRMARQPADRDHRFGHWKIEDLASLITSIIMFYVGFDVLRD
                     TIQKILSREETVIDPLGATLGIISAAIMFVVYLYNTRLSKKSNSKALKAAAKDNLSDA
                     VTSLGTAIAILASSFNYPIVDKLVAIIITFFILKTAYDIFIESSFSLSDGFDDRLLED
                     YQKAIMEIPKISKVKSQRGRTYGSNIYLDITLEMNPDLSVFESHEIADQVESMLENRF
                     GVFDTDVHIEPAPIPEDEILDNVYKKLLMREQLIDQGNQLEELLTDDFVYIRQDGEQM
                     DKEAYKTKKELNSAIKDIQITSISQKTKLICYELDGIIHTSIWRRHETWQNIFHQETK
                     KE"
     gene            36017..38713
                     /locus_tag="VQ865_000393"
     CDS             36017..38713
                     /locus_tag="VQ865_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HET3134812.1"
                     /translation="MSKEQKRQAFYTQSPEEVLQAVDATEQGLSSSEAEKRLVEFGHN
                     ELEEGEKRSILVKFIEQFKDLMIIILVAAAILSVVTSGGEDIADAIIILAVVIINAAF
                     GVYQEGKAEEAIEALKSMSSPVARVLRDGHMAEIDSKELVPGDIVALEAGDVVPADLR
                     LIEANSLKIEEAALTGESVPVEKDLSVELATDAGIGDRVNMAFQNSNVTYGRGMGVVV
                     NTGMYTEVGHIAGMLQDADETDTPLKQNLNNLSKVLTYAILAIALVTFVVGVFIQGKN
                     PLGELLTSVALAVAAIPEGLPAIVTIVLSLGTQVLAKRHSIVRKLPAVETLGSTEIIA
                     SDKTGTLTMNKMTVEKVFYDAVLHDSADDIELGLEMPLLRSVVLANDTKIDVEGNLIG
                     DPTETAFIQYALDKGYDVKGFLEKYPRVAELPFDSDRKLMSTVHPLPDGRFLVAVKGA
                     PDQLLKRCLLRDKAGDIAPIDEKVTNLIHTNNSEMAHQALRVLAGAYKIIDSIPENLT
                     SEELENDLIFTGLIGMIDPERPEAAEAVRVAKEAGIRPIMITGDHQDTAEAIAKRLGI
                     IDANDTEGHVLTGAELNELSDEEFEKVVGQYSVYARVSPEHKVRIVKAWQKQGKVVAM
                     TGDGVNDAPALKTADIGIGMGITGTEVSKGASDMILADDNFATIIVAVEEGRKVFSNI
                     QKTIQYLLSANTAEVLTIFLSTLFGWDVLQPVHLLWINLVTDTFPAIALGVEPAEPGV
                     MNHKPRGRKASFFSGGVLSSIIYQGVLQAALVMSVYGLAIAYPVHVGDNHAIHADALT
                     MAFATLGLIQLFHAYNVKSVYQSILTVGPFKSKTFNWSILVSFILLMATIVVEPLEGI
                     FHVTKLDLSQWGIVMAGSFSMIIIVEIVKFIQRKLGFDKNAI"
     gene            38726..39517
                     /gene="yghU"
                     /locus_tag="VQ865_000394"
     CDS             38726..39517
                     /gene="yghU"
                     /locus_tag="VQ865_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HET3134813.1"
                     /translation="MSAYQLPTVWQDEASNQGAFTGLNRPTAGARFEQNLPKGEQAFQ
                     LYSLGTPNGVKVTILLEELLEAGFKEAAYDLYKIAIMDGDQFGSDFVKLNPNSKIPAL
                     LDQSGTENVRVFESAHILLYLAEKFGAFLPSNPVEKVEVLNWLFWQAGAAPFLGGGFG
                     HFFNYAPEKLEYPINRFTMEVKRQLDLLDKELAQKPYIAGNDYTIADIAIWSWYGQLV
                     QGNLYQGSAKFLDASSYQNLVKWAEKIANRPAVKRGLEVTYTEIK"
     gene            39633..40043
                     /locus_tag="VQ865_000395"
     CDS             39633..40043
                     /locus_tag="VQ865_000395"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3134814.1"
                     /translation="MEKKIVKDILFLSQVSQPASQEDLYLARDLQDTLLANRDTCVGL
                     AANMIGVQKRVIIFNLGLVPVVMFNPVLLSFEGSYEAEEGCLSLVGVRSTKRYETIRL
                     AYRDSKWQEQTITLTGFPAQICQHELDHLEGRII"
     gene            40055..41650
                     /locus_tag="VQ865_000396"
     CDS             40055..41650
                     /locus_tag="VQ865_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134815.1"
                     /translation="MKRIVFELIFIATTWYIFLPPLNLTSWEFLFFLCGHLLVVAILF
                     GFGKGINLVKTVHVRHGKAEAALNLEGFKINRLGKILLASIGGILLLAALVSLVTSSM
                     FQAKNYANVVTVTEKDFTEFPKSDTSKVPILDRSTAEKIGDRYLGSLTDKVSQYVAAD
                     TYTQLTIDGKPYRVTPLEYADPIKWFNNQAKGIGEYIKVDMVTGNADLVDLKTPIKYS
                     DSEYFNRDVKRHLRLKYPTKIFKTPSFEVDDEGNPFYVATVYQKQFGLAVPRPASVII
                     LDATNGETKEYSLSDVPEWVDRIYPAEETIEQINYNGKYKDGFLNAMISKKNVTQTTN
                     GYNYLSIGNDIYLYTGVTSANADESNLGFILENMRTGEITKYSLASATEESARESAEG
                     AVQEKSYKATFPILINLNDKPLYIMGLKDNAGLVKEYALVDAVEYQNVIVATTVEEML
                     SKYANKNDLEIDNATTESINGVVADLKSAVIKGDTVYFFKVDGKIYKVKASVSDDLPY
                     LENGKTFEGQVGKDNYLKTFKLR"
     gene            41717..41881
                     /locus_tag="VQ865_000397"
     CDS             41717..41881
                     /locus_tag="VQ865_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000508323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YczI family protein"
                     /protein_id="HET3134816.1"
                     /translation="MGFYLMVASMLLGLLALKIGFSQFKEKKDKFLSILTSLAGTALV
                     LVAVWLGWPK"
     gene            41960..42688
                     /gene="yaaA"
                     /locus_tag="VQ865_000398"
     CDS             41960..42688
                     /gene="yaaA"
                     /locus_tag="VQ865_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HET3134817.1"
                     /translation="MKILIPTAKEMNTDLPSIEAIPLKPESQAVLDALALYSASQLES
                     FYKVSAEKAAEEFQNIQALKRQTAQHYPALKLFDGLMYRNIKRDKLTEAEQDYLENHV
                     FITSALYGVVPVLSPMAPHRLDFLMKLKVAGKTLKSHWKAAYDETLKKEEVIFSLLSS
                     EFETVFSKEIRAKMVTLKFMEDRGGQLKIHSTISKKARGAFLTALIENQVQTVGEARR
                     LNFAGFVYREDLSQPQGLVFVKEV"
     gene            complement(42965..43513)
                     /locus_tag="VQ865_000399"
     CDS             complement(42965..43513)
                     /locus_tag="VQ865_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3134818.1"
                     /translation="MSKKVLFIVGSLRQGSFNHQMALEAEKALAGKAEVSYLDYSALP
                     LFSQDLEVPTHPAVAAAREAVLVADAIWIFSPVYNFSIPGTVKNLLDWLSRALDLSDT
                     RGVSALQDKFVTVSSVANAGHDQLFAIYKDLLPFIRTQGVGDFTAARVNDSAWADGKL
                     VLEETVLNSLEKQAQDLVEAIK"
     gene            43834..44322
                     /locus_tag="VQ865_000400"
     CDS             43834..44322
                     /locus_tag="VQ865_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HET3134819.1"
                     /translation="MKKRQNKAKNNLLWQYGLGMTILFVVISASFLYMVSLSMKPYQT
                     AKSEGEKLAQQYAGLEQADQVDLYNGLESYYSVLGRNKQQEALAVLIGKDDHKIYVYQ
                     LNQGVSQEKAETVSKEKGAGEIDKIIFGRYQDKPIWEVKSGSDFYLVDFETGALVNKE
                     GL"
     gene            44319..45506
                     /locus_tag="VQ865_000401"
     CDS             44319..45506
                     /locus_tag="VQ865_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3134820.1"
                     /translation="MKLSNRVLEMEESVTLAAGARAKALKAEGRDILSLTLGEPDFTT
                     PKNIQDAAIASIRDGRASFYTVTSGLPELKAAVNSYFERFYGYSVASNQVTVAAGAKY
                     SLYTFFMAVVNPGDEVIIPTPYWVSYGDQVKMAEGVPVFVSTKEDNHFKVTVDQLEAA
                     RTDKTKVLVLNSPSNPTGMIYTREELLAIGNWAVENDILILADDIYGRLVYNGHEFTP
                     ISSLSEAIRKQTVVINGVSKTYAMTGWRIGYAVGEADIIAAMSKIAGQTTSNPSAVAQ
                     YAAVEALSGEQDTVESMRQAFEERLNTIYPLLAEVPGFEVVKPQGAFYLFPNVKKAME
                     MKGYTDVTDFTTAILEEAEVALVTGAGFGAPENVRLSYATDLDTLKEAVERLKAFMGS
                     END"
     gene            45499..45864
                     /locus_tag="VQ865_000402"
     CDS             45499..45864
                     /locus_tag="VQ865_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3134821.1"
                     /translation="MIDHFEIKVKDLQISEGFYRSFLAPLDYKMAFKTSSLISFLSPN
                     SPHPGGDFWLTQGTQDPVHFAFLAENKEEVQACYEAGLEAGGRDNGVPGYRSEHPIYY
                     AAFMIDLDGNNIEVVCHKE"
     gene            45880..47226
                     /gene="asnS"
                     /locus_tag="VQ865_000403"
     CDS             45880..47226
                     /gene="asnS"
                     /locus_tag="VQ865_000403"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HET3134822.1"
                     /translation="MMTKRVTIIDVKDYIGQEVTIGAWVANKSGKGKIAFLQLRDGTA
                     FFQGVAFKPNFVEKFGEEVGLEKFDVIKRLSQETSVYVTGIVKEDERSKFGYELDITD
                     IEVIGESQDYPITPKEHGTDFLMDNRHLWLRSRKQVAVLQIRNAIIYATYEFFDKNGF
                     MKFDSPILSGNAAEDSTELFETDYFGTPAYLSQSGQLYLEAGAMALGRVFDFGPVFRA
                     EKSKTRRHLTEFWMMDAEYSYLTHDESLDLQEAYVKALLQGVLDRAPQALETLERDTE
                     LLKRYIAEPFKRITYDQAIDLLQEHENDEDADYEHLEHGDDFGSPHETWISNHFGVPT
                     FVMNYPAAIKAFYMKPVPGNPERVLCADLLAPEGYGEIIGGSMREEDYDALVAKMDEL
                     GMDRTEYEFYLDLRKYGTVPHGGFGIGIERMVTFAAGTKHIREAIPFPRMLHRIKP"
     gene            47379..47669
                     /locus_tag="VQ865_000404"
     CDS             47379..47669
                     /locus_tag="VQ865_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018030687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HET3134823.1"
                     /translation="MAKYEILYIIRPNIEEEAKNALVARFDSILTDNGATVVESKTWE
                     KRRLAYEIQDFREGLYHIVNVEANDDAALKEFDRLSKINADILRHMIVKIDA"
     gene            47681..48151
                     /gene="ssbA"
                     /locus_tag="VQ865_000405"
     CDS             47681..48151
                     /gene="ssbA"
                     /locus_tag="VQ865_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SsbA"
                     /protein_id="HET3134824.1"
                     /translation="MINNVVLVGRMTRDAELRYTPSNVAVATFTLAVNRTFKSQNGER
                     EADFINVVMWRQQAENLANWAKKGSLIGVTGRIQTRSYDNQQGQRVYVTEVVAENFQM
                     LESRSVREGHTGGAYSAPTANYSAPTNSVPDFSRNENPFGATNPLDISDDDLPF"
     gene            48183..48422
                     /locus_tag="VQ865_000406"
     CDS             48183..48422
                     /locus_tag="VQ865_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HET3134825.1"
                     /translation="MAQQRRGGFKRRKKVDYIAANKIEYVDYKDTELLSRFVSERGKI
                     LPRRVTGTSAKNQRKVTTAIKRARVMALMPFVNED"
     gene            48717..50117
                     /locus_tag="VQ865_000407"
     CDS             48717..50117
                     /locus_tag="VQ865_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional Cof-type HAD-IIB family
                     hydrolase/peptidylprolyl isomerase"
                     /protein_id="HET3134826.1"
                     /translation="MDAKLRYKAKKIKIVFFDIDDTLRNSKTGFIPTTIPTVFKQLRE
                     KGILTGIASGRGIFGVVPEIRDLKPDFFVTLNGAYIEDKKGQVIYQHQIEKSDVEEYI
                     SWAKQEGIEYGLVGSHDAKLSTRTDMMSEAINPIYPDLDVDPDFHEKEDIYQMWTFED
                     KGDDLHLPDSLSDKLRMVRWHQHSSDIVPISGSKATGVEKVVEHLGLKPEKVMVFGDG
                     LNDLELFDYAGISVAMGISHDKIKEKADYITKTLEEDGIFDALEVFGMVEKELHFPQV
                     DIETVEGLLATIKTNHGDLRIKLFPEHAPKTVANFVSLSKDGYYDGVIFHRIIKDFMI
                     QGGDPTGTGMGGESIYGESFEDEFSEELYNIRGALSMANAGPNTNGSQFFIVQNQHLP
                     YSKKEITRGGWPEPIAEIYANQGGTPHLDRRHTVFGQLADEASYAVLDAIAAVETGAM
                     DKPVEDVVIETIEIED"
     gene            50119..50478
                     /locus_tag="VQ865_000408"
     CDS             50119..50478
                     /locus_tag="VQ865_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HET3134827.1"
                     /translation="MKIGDKLKGRITGIQPYGAFVELETGDTGLIHISEIRTGFIENI
                     HETLKVDEEVQVQVLDLDEFTGKASLSIRTLEEEKYQFPRRRRFSSDRFNYGFAPFRR
                     MLPIWTGEALHHLKKKK"
     gene            50532..51281
                     /locus_tag="VQ865_000409"
     CDS             50532..51281
                     /locus_tag="VQ865_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000390787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HET3134828.1"
                     /translation="MEEEQLLKSGERINQLFSTDIKIIQNREVFSYSVDSVLLSRFPR
                     FPKKGLIVDFCAGNGAVGLFASTRTQAQILSVEIQERLADMAERSVRLNGLEEQMQVI
                     CDDLKNMPAHIQGSKVDMILCNPPYFKVDPYSNLNESEHYLLARHEITTNLEEICRSA
                     QSILKSNGRLAMVHRPDRLLDILDTLKRHNLAPKRLQFVYPKREKEANMLLIEAIKDG
                     STSGFKVLPPLIVHNDDGSYTPEIEEIYYGS"
     gene            51271..51570
                     /locus_tag="VQ865_000410"
     CDS             51271..51570
                     /locus_tag="VQ865_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HET3134829.1"
                     /translation="MDHKAYMYVLECRDGSYYIGYTTDVRRRLAIHNSGKGAKYTRAR
                     LPVKLIYAQGFASKEEAMSAEALLKRKKRPQKEEFLSENQDRNLLSYFEESWGVL"
     gene            51641..52576
                     /locus_tag="VQ865_000411"
     CDS             51641..52576
                     /locus_tag="VQ865_000411"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HET3134830.1"
                     /translation="MSKILVFGHQNPDSDAIGSSVAFAYLAKEAYGLDTEAVALGTPN
                     EETAFVLNYFGVEAPRVITSAKAEGAEQVILTDHNEFQQSVSDIAEVEVYGVVDHHRV
                     ANFETASPLYMRLEPVGSASSIVYRMFKEHGVAVPKEIAGLMLSGLISDTLLLKSPTT
                     HPTDKIIAPELAELAGVNLEEYGLAMLKAGTNLASKSAEELIDIDAKTFELNGNNVRV
                     AQVNTVDIAEVLERQAEIEAAMQAANESNGYSDFVLMITDIVNSNSEILALGANMDKV
                     EAAFNFKLENNHAFLAGAVSRKKQVVPQLTESFNA"
     gene            52662..53174
                     /locus_tag="VQ865_000412"
     CDS             52662..53174
                     /locus_tag="VQ865_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000892254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoylalanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HET3134831.1"
                     /translation="MLENGDLIFVRDGSDMGQAIQTSTGNYSHVAIYLDGMIYHASGQ
                     AGVVCQEPADFFESNHLYDLYVYPEMDIQSVKERACRHLGAPYNASFYPDAAGFYCSQ
                     YIAEILPIFETIPMKFGDGEQEISDFWREYYIELGLPVPLNQAGTNPSQLAASPLLQC
                     KERNLHDSDF"
     gene            53211..53806
                     /locus_tag="VQ865_000413"
                     /pseudo
     CDS             53211..53806
                     /locus_tag="VQ865_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809149.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
     gene            53907..54101
                     /locus_tag="VQ865_000414"
     CDS             53907..54101
                     /locus_tag="VQ865_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3134832.1"
                     /translation="MSLENKLEQATGAVKEGFGKVTGDSKTELEGAVEKTVAKAKDVV
                     EDAKGAVEGAVEGLKNVFTK"
     gene            complement(54147..55592)
                     /locus_tag="VQ865_000415"
     CDS             complement(54147..55592)
                     /locus_tag="VQ865_000415"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HET3134833.1"
                     /translation="MIKIETVLDILKKDGLFREIIDQGHYHYNYSKVIFDSISYDSRK
                     VTEDTLFFAKGAAFKKEYLLSAITQGLAWYVAEKDYEVDIPVIIVNDIKKAMSLIAME
                     FYGNPQEKLKLLAFTGTKGKTTATYFAYNILSQGHRPAMLSTMNTTLDGETFFKSALT
                     TPESIDLFDMMNQAVQNDRTHLIMEVSSQAYLVHRVYGLTFDVGVFLNITPDHIGPIE
                     HSSFEDYFYHKRLLMENSRAVIINSDMDHFSVLKEQVEDQDHDFYGSQFDNQIENSKA
                     FSFSATGKLAGDYDIQLIGNFNQENAVAAGLACLRLGASLEDIKKGIAATRVPGRMEV
                     LTQKNGAKVFIDYAHNGDSLKKLINVVETHQTGKIALVLGSTGNKGESRRKDFGLLLN
                     QHPEIQVFLTADDPNYEDPMAIADEISSYINHPVEKIADRQEAIKAAMAITNHELDAV
                     IIAGKGADCYQIIQGKKESYPGDTAVAENYL"
     gene            55698..57320
                     /locus_tag="VQ865_000416"
     CDS             55698..57320
                     /locus_tag="VQ865_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3134834.1"
                     /translation="MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAY
                     AAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMT
                     GLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLK
                     PYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFL
                     AQEGSLKRVFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFT
                     NYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQD
                     SLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALVLFVFAVLQSIILGLYMVLSPM
                     LQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICK
                     VTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGG
                     GLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS"
     gene            57523..59481
                     /locus_tag="VQ865_000417"
     CDS             57523..59481
                     /locus_tag="VQ865_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3134835.1"
                     /translation="MKKSKSKYLTLAGLVLGTGVLLSACGNSSTASKTYNYVYSSDPS
                     SLNYLAENRAATSDIVANLVDGLLENDQYGNIIPSLAEDWTVSQDGLTYTYKLRKDAK
                     WFTSEGEEYAPVTAQDFVTGLQYAADKKSEALYLVQDSVAGLDDYITGKTSDFSTVGV
                     KALDDQTVQYTLVKPELYWNSKTLATILFPVNADFLKSKGDDFGKADPSSILYNGPFL
                     MKALVSKSAIEYKKNPNYWDAKNVFVDDVKLTYYDGSDQESLERNFTAGAYTTARLFP
                     NSSSYEGIKEKYKNNIIYSMQNSTSYFFNFNLDRKSYNYTSKTSDIEKKSTQEAVLNK
                     NFRQAINFAFDRTSYGAQSEGKEGATKILRNLVVPPNFVSIKGKDFGEVVVSKMVNYG
                     KEWQGINFADGQDPYYNPEKAKAKFAEAKKELEAKGVQFPIHLDKTVEVTDKVGIQGV
                     SSIKQSIESVLGSDNVVIDIQQLTSDEFDSSGYFAQTAAQKDYDLYHGGWGPDYQDPS
                     TYLDIFNTNSGGVLQNLGLEPGEANDKAKEVGLDVYTQMLEEANKEQDPAKRYEKYAD
                     IQAWLIDSSLVLPSVSRGGTPSLRRTVPFAAAYGLTGTKGIESYKYLKVQDKIVTTDE
                     YAKAREKWLKEKEESNKKAQEELAKHVK"
     gene            59653..60213
                     /locus_tag="VQ865_000418"
     CDS             59653..60213
                     /locus_tag="VQ865_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134836.1"
                     /translation="MKLKLLRVDTKVIMGSFLLVLSSLLALLLPLILKGLIDGSSIEN
                     IGSKVFQSFLIFIGQALFSSIGYYLFSQSGEKKIAKIRKKVIEGLIYAEKSFFDKSQS
                     GELTSAIVNDTSVIREFLITTFPNIILSLVMVLGSIVVLFSLDWNLSLLLFITLPCMM
                     FIILLLSNISEKYSRRLQEEIGFLTG"
     gene            60214..60588
                     /locus_tag="VQ865_000419"
     CDS             60214..60588
                     /locus_tag="VQ865_000419"
                     /inference="COORDINATES: protein motif:HMM:NF012869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134837.1"
                     /translation="MTEKIQEHELIKTNQAEKSVQDVLDNCIERVQNNSLKSDRVTSF
                     ETPFALLFIFATIAVMLTYGGYRVSAGYISVGTLVSFLIYLFQLLNPISNIANFVTVY
                     SRSKGSSVALENLLAVPKEKFE"
BASE COUNT        17882 a        11272 c        13718 g        17748 t
ORIGIN      
        1 aagacagaaa ttgttcaaga attaatgact gagttttcgt tagttcttct tctaaaagcc
       61 attaaactag ctcgttcgac ctactactat cacttgaaac agctagacaa aacagataag
      121 gactaaggct ggcaatacca acacgattct tatcatcggt tcctagagag taagggaatt
      181 caagcatcta tgtcacgcaa gggaaacagc caagacaacg gtatgatgga gtccttcttt
      241 ggcattttaa aatccgaaat gttttatggc tatgagaaaa catttaaatc acttaatcaa
      301 ttggaacaag ccattataga ctatattgat tattacaaca ataagaaaat taagttaaaa
      361 ctaaaaggac ttagccctgt gcaatacaga actaaatcct tcggataaat taattgtcta
      421 actttttggg ggcagtacac aatacctgat agtatgcgtt ttattgtggg aagattttcc
      481 tcattttcta gtgaaattga actttttcta acatcttttg atagatgact tcttaatcaa
      541 ttatcatttc cattgttgtt tcttggggtt tcatcccttg tctttgataa aagcggagag
      601 caccctcgtt atcattccag acacttaggg ttagattatt gcagccaatt tctttagcat
      661 aatagcagaa aaatgacaat aaaatagccc ctagatattt tgaaaggaaa gcataggggc
      721 tatatagttt aatcaaaata aagcaaatct ttgctggtgc ttgtaaagag gtcgaagcca
      781 tccttggtaa caacaccgca gtcttcaata cgaacaccga ctttaccagg gatatagata
      841 cctggttcaa cagagaagca catgccttct tcgatgacca tgtcgtttcc ttccatgata
      901 gatgggaatt catggacatc cataccgata ccatgcccga gacggtgatt gaagtactca
      961 ccataaccag ctttttcgat gacctcacgg gcagcgcggt ccacttcatg agcagtcaca
     1021 cctggcttga taaagtcaag agcagcttgt tgggcttcaa gagtcaagtt gtaaatatct
     1081 ttcttgaatt ggtctggttt gccgacagcg actgtacgag tcatatctga cgcatagcca
     1141 ttgaccagaa cacccaggtc aaagaggaga agagcatcat tttcaacctt attagctgct
     1201 ggaatgccgt gtggattcgc agcattatca ccagtcaaga ccatggtatc aaagctcatt
     1261 tcataacctt cacgtttcat ggcaaagtcg atttgtgcga tgatatctgt ctcagtctta
     1321 tcaagagaaa tattgtcaaa accaacatga acagccttgt cagcataaag acctgcaacc
     1381 atcatttttt gcacttcatc agctgatttg atgaggcgca tgcgttggat acgaggagtg
     1441 aggttgtcaa actcagcagt ctcaaaaact gttttcaaac catggtattt ggtcaagatg
     1501 agattgtcaa actcaacagc gacacgtttg aagtcaagtt gtggaagagc atgtttgatt
     1561 ttttgccatg gattttcaga atcgacatag cccactactg ggaaggaaac ggtgctactt
     1621 gcacgttcta cttcaagagc tgggacaaag aggagaggtt cctgatccgc taggacaaag
     1681 aggaacattt ggcgttcatg gggatcactg taaaaaccag tgaggtaatt gattgtgacg
     1741 gggtcagata cgacagcgac gtctagtttt tctgattcaa gatatgttag gatttgttgt
     1801 aatttagaca tatgctacct tctttctacc cctctatttt ggcaaaaaat gagagaaaat
     1861 gcaagggaga agggtaaaag aaaagacaaa aaactccgac aagataacgg agttctttga
     1921 tatcattttc ctttgtttaa gaaaagtcag ccttgctttt gacgtcactg tactcttcag
     1981 cgatttcttg gctgaggata tcctcatagg cagggagttg gatatcctga ccatatttct
     2041 tcttgagggc agtagtaact aggcgataag ccagattggc attacgagag aggataggcc
     2101 cgtggaagta ggaaccaaag acattcttat aatgaacccc ttcaccgacc ttttcttcgt
     2161 tgtttccatt tccatagaca acctgtccca gcggtttttg gtcatcagag aggaaggtac
     2221 ggccttggtg attttcaaat ccatagtagg tttcatcgaa atcttcattg tgaatcttga
     2281 tgtcaccgat aaaacggtta ttggtctggt tgagcgtgta gtgtcccatg acccctagcc
     2341 cttcgatacg ttttcctgaa gcttcaacat aatattgacc caatagttgg aaaccaccgc
     2401 agatagccag aactacaccg tcgttttgga tgtagttgtc aatgctctct tttttagcag
     2461 gtaggtcgtc tgcaatgata ctttgttcaa agtcttgacc accaccgaaa aaggcgatgt
     2521 cgtagtgatt ttcatcaaag tcatcatgga gagaaacgat gtcaacggtc acatgggctc
     2581 ccagtttttc agccacatat ttgagcatga ggatgtttcc attgtccccg taggtattca
     2641 tgagatttcc gtagaggtgg gcaatgttga gctgataggg gtaattgcca tcttttgagg
     2701 aaagtgaagt ataaaccatt agttcatctc ctttctaaca atctgacgac tagccagcag
     2761 ttcacgaaat tccagcatgg cagtataagt tgccagaata taggcatgct tgcagtcttg
     2821 attctcaatg gtcttgagaa cttgctccag attactcgtt tcagtgattt tctcagctgg
     2881 atagccagtc actcggaggc gacgagcgat ttcagaatga cgaacaccgc cagcgttgat
     2941 ttcaggaatg tccatgtcag tgatttgctc aaagtctgca tcccagatcc agctagtgtc
     3001 aattccatct gcatagttgg cattaaggag gacagatagg ctaaatggat aaggtgctag
     3061 tttgatcatt tcgatagctt gggttgcacc gactggattt ttaatcaaga caagggtaca
     3121 tttcttgtca ccgatatgaa aggtttcttg gcgtccaaag acagcacggc tcttgtcaaa
     3181 tccctgtttg atgagttgcg aatcggcacc taggaaacgg gcgatggcca cagcagctag
     3241 ggcgttatag atattataga gcccgccgat ttggataccg tattcttggc cgtctatgac
     3301 aaagcgagag cgattgttgg tcaactcaac cagttttgtc aaacgatagt cgagatcagg
     3361 acgtttacat ccacaacctt cacagatata ggcacccaag tttgcatagg tattatgctc
     3421 atatttgagg atgccttggc agtcaggaca gagaatccct tcggtattgt agtgagccag
     3481 ttgggctggt cctttttcca agtcaaaacc aaaatactct atagggtttg gaatagttgg
     3541 cttgtagaaa agtggactgt ctccgttaag gagaacagta gcagttggaa cttttcgaat
     3601 ggcatccaat atcatgttat aggtagtata gatttcaccg aaacggtcca tctggtcacg
     3661 gaagatatta gtaatgacaa aaagactagg ctggatatag tcacagatac gagatagact
     3721 ggcttcgtca atttcgagga cggcaatatt tttcccagtt tttgaagatt tggctgttag
     3781 gaaggttgtt gcaatccctg taatcatgtt ggcaccgctt gggttggtta gaacttgacc
     3841 ataaacctct tttaaaatgc cgacagtgag ggcagttgtc agggtttttc catttgttcc
     3901 agtgacaacg acaatctcgt agttcttagc taggttttgt aaaatatctt tatcaaattg
     3961 aagggcgact ttacctggga gcgtacttcc acgtccaaga cggcttaaaa cgaagtggga
     4021 agaacgccca gcaagaaggc ccaaagtagt ttttaagttc atgtttctat tatatcacaa
     4081 aagagggaaa agacagattt ggtgtttcgt agaagtaaaa acagcccaaa gagggctgtc
     4141 agttaagatg agatttcaac ttaaatcgca aacaagtcat tcaagttctc agccaaggtt
     4201 gggtgagtga agatttgttt tgtgaagtaa gtgtaaggaa tcttgttgtc catagcaaca
     4261 gtaatgatgt tgatgatttc ttgagaacct tctgagaaga tgcttgcacc aagaatttct
     4321 tttgtttcag tattaacaac agctttgaaa gctccgcgaa ggtctccatt tacgtgacca
     4381 cgaggcatgg ctgcaacagg gatttctttc actgcgtatg gaagtttcaa atcagctgct
     4441 tggctttcag tcaaaccaac ttgtgaaagt gcaggtgtga tgaacatagt atttggcaca
     4501 ttgagacggt cctcaagtgt gtagctgcca tctccagcaa ggtagctgta aacaacacgg
     4561 aagtcatcaa gtgaaatgta agtaaattga agaccaccgt tgacatctcc aactgcaaag
     4621 acaccaggaa cgtttgtttg acagtgttta tctactttaa tagcgccacg ttcagttagt
     4681 tcaatatctg tattttcaag ttgaagtggt tctacatttg gtttgcgtcc agttgcgtag
     4741 agaagggcgt cgaaacggta agtttcgtct tcagttacga caagcacttg gtcaccgtcg
     4801 tttttaattt cagtagtatg gatattttga agcaattcaa taccgtcttc ttccaggtat
     4861 tgtttagcaa gagctgcgat ggaaggttct gcacgaggta ggaatgtatc caaggcatct
     4921 aggactgtaa ccttgcttcc tagtttattg taaaggccag caaattcaag accgatattt
     4981 ccgccaccaa ggactccaag tttttcaggc aatttatcca agctttggat acctgttgag
     5041 tcaaagacgt ttttgcttgt agcaagtcca gggattggca agacgtttga aacagcacca
     5101 gtgttgatga cgatagtttc agcagtcaat tcttgttttt catcaccagc ttggatttcg
     5161 atgactttat ttgaaaggaa gtgagcttca gcatcaaaga tattgacgcc agtaccagca
     5221 acagtcgtat agtttttacc gttgaggcga ccagtgatcg tgtttttggt agcaatgact
     5281 tcttcaaaag acaagtcttt ctcagcagca accagcaaag ttttagttgg gatacaaccg
     5341 atgttgatac aagttccacc gtacatagct ttgctacgtt caacgagggc aacttttttg
     5401 ccagctgaag ccaatttacc agctagtgtt ttaccagctt taccaaatcc gataacgatt
     5461 aaatcataag ttaacattta gaattcctcc tattcgaatt acattctagc acaagaaaaa
     5521 aacttttgca caattctgct acgaaaaaga cagaaaaaga tgaaaacgct ttccagacaa
     5581 aaaactagta attttttgac aagcttgata aactaaaatc ctatctattt ttatataata
     5641 aagaataaat gttcgaaaat aggaggtttt atgaaatcga atcgttatat tattgccttt
     5701 gctggggtca ttttacactt aatgctgggt tcgacttatg cctggagtgt ttatcgtaac
     5761 cctattattg aaaaaacggg atgggatcag gcttctgttg ccttcgcctt tagtctagca
     5821 atcttttgtt tgggcttatc ggctgcattt atggggcgtt tggtagaaaa atttggtccg
     5881 aaagtcatgg gaagtctatc tgcttttcta tacgcaggtg gaaatatctt aacaggattt
     5941 gcaatagacc gtcaggagct gtggttgttg tatctcgctt atggcatttt aggtgggctt
     6001 ggtttgggag caggctatat tacccctgtg tcgacgatta taaaatggtt tcctgataaa
     6061 cgtggtctcg caacaggttt agcgattatg gggtttggtt ttgcttcttt attgactagt
     6121 cccatagcgc aacacctcat cgcaggggta gggcttgtag aaacttttta tattttagga
     6181 gcaagttact ttattatcat gctcctagct tcacaattca ttaagcgtcc aaatgagcaa
     6241 gagcttgcaa ttttatcttc ttcagggaaa gaaaaaacag cctctttgac gcaaggaatg
     6301 gctgcaaatc aggctctaaa aagcaatcgg ttttatatgc tttggattat tttctttatc
     6361 aacatagctt gtggtttagg cttaatttca gcggcatcgc caatggcaca ggagatggct
     6421 ggcttgtcta caagtcatgc agcagtaatg gtgggtgttt tggggatttt caatggattt
     6481 ggtcgcttgc tctgggcgag tttgtctgac tatatcggtc gccctctaac ctttagtata
     6541 ttactgcttg ttaatctttt cttttctctc tcactttggc tctttacaga ttccgtttta
     6601 tttgtagtcg ctatgtctat tttgatgact tgctatggag ctggtttttc attgatccca
     6661 gcttatctca gtgatatttt tggaaccaag gaattggccg ctctgcatgg atatatttta
     6721 acagcttggg caatggctgg tttagcggga cctattttat tagcagagac ttataaaatg
     6781 gctcattcgt acacacaaac cttgttcgtt tttctcattt tatacagtat cgccttggct
     6841 ttgtcttatt atctaggtcg ttcaatcaaa aaagaaagtc aaaaaccgct tacatgattt
     6901 tctgtagaaa tgggactatc ttttgctctg gtcttgtgtt atactagata ggttgcaaag
     6961 aaaacagtac ttttcttttg tggaaaagaa gcaacacgat tttatatcta gttatatgaa
     7021 aatacgtcat aaaaagaaaa gtataaacta agccctatag ggtggcttcg caccaccttt
     7081 agaaagaaga ataacgtgaa atttaatgaa ttaaacttgt ctgctgattt gctggcagaa
     7141 attgaaaaag ctggttttgt agaagctagt cctatccaag aacaaactat tcctttggcc
     7201 cttgaaggca aggatgttat cggtcaagct cagactggta caggaaaaac tgcagccttt
     7261 ggcttgccta cccttgaaaa aatccgtaca gaagaagcga ctatccaagc cttagtcatc
     7321 gctccaactc gtgaactagc tgtccaaagt caagaagaac tcttccgctt tggtcgtagt
     7381 aagggagtca aagtccgttc agtatatggc ggatcaagca ttgaaaaaca aattaaggct
     7441 cttaaatctg gtgcccatat cgtggtggga actccaggtc gcctcttgga cttgattaaa
     7501 cgcaaggcct tgaaattaca aaacattgaa acccttatcc ttgacgaagc ggatgaaatg
     7561 cttaacatgg gcttccttga agacatcgaa gccattattt cccgtgtacc tgagaaccgt
     7621 caaactttgc ttttctcagc aactatgcca gatgccatca aacgtatcgg tgttcagttt
     7681 atgaaagccc ctgaacatgt caagattgcg gctaaggaat tgacaacaga attggttgac
     7741 cagtactata tccgtgttaa ggaacaagaa aaatttgaca ccatgactcg tctcatggat
     7801 gtggcacaac cagaactcgc tattgtattt ggtcgtacca aacgccgtgt ggatgaattg
     7861 actcgtggtt tgaaaattcg tggcttccgt gcagaaggaa ttcatggcga cctagaccaa
     7921 aacaaacgtc ttcgtgtcct tcgtgacttt aaaaatggca atcttgatgt tttggttgcg
     7981 acagacgttg cagcgcgtgg tttggatatt tcaggtgtga cccatgtcta caactacgat
     8041 attccacaag atcctgagag ttatgttcac cgtatcggtc gtacaggtcg tgctggtaag
     8101 tcaggtcaat ctattacttt tgttgctcca aacgaaatgg gttaccttca aatcattgaa
     8161 aacttgacta agaaacgcat gaaaggtctc aaacctgcaa gtgtagaaga atccttccaa
     8221 tcaaaaaaac aggtagctct caagaaaatc gaacgtgatt ttgcagatga aaccattcgt
     8281 gccaattttg agaaatttgg taaggatgct cgcaaattgg ctgctgagtt tactccagaa
     8341 gaattggcaa tgtatatctt gagtctgaca gtccaagacc cagatagcct tccagaagtg
     8401 gagattgcac gtgaaaaacc actaccgttt aaaccatcag gtaatggttt cggtggtaaa
     8461 gctaagggag gtcgtggagg ccgtcgtggg gacgaccgtc gagagcgtga tcgccgtggc
     8521 aatggtcgcc gtgatgagtt caaaaaagga agtcgtggca acgatcgttt tgataaggaa
     8581 aaacgttacc gtaaggataa taaaaaacca cgcaatactt taagcgaaaa gcaaacaggc
     8641 tttgttattc gtaacaaagg tgataaataa gaaaaagcgg ttcaaaatga atcgcttttt
     8701 tatataagga gaccgaatgt gaaaaagaca aataaaatta ttatattatc ttttataata
     8761 ttatgataca caaaaatagg caacttgtca atagaaaagg aacaatttaa ttaaaaatat
     8821 tctggttttt aattaaattg taagtcaatg caagtcaata aggaattttc agataattat
     8881 tgaaaaagag acgtttttat gttataatga tagcgattaa attcgaggtg aaaaatggca
     8941 catttattag aaaaaactag aaaaattaca tcaattttga aacgctcaga ggagcagttg
     9001 caggatgagc ttccttacaa cgctattacg cgtcagttag cggatattat tcattgcaat
     9061 gcctgcatta tcaatagtaa gggacgtctg cttggctatt ttatgcgtta taaaacaaat
     9121 acagatcgcg tagagcaatt cttccaaact aagattttcc cagatgacta cgttcaaggg
     9181 gctaatatga tttacgaaac agaagcaaac ttacctgttg agcatgatat gagtattttc
     9241 cctgttgaga gtagagatga ttttccagat ggcttgacga ctattgcacc gattcatgta
     9301 tcggggattc gccttggttc tttgattatt tggcgtaatg ataaaaaatt cgaagatgag
     9361 gacttggttc ttgttgagat tgccagtacc gttgttggga ttcagcttct taacttccaa
     9421 cgtgaagaag atgagaaaaa tattcgtcgt cgtactgctg tcaccatggc ggtcaatacc
     9481 ctttcttact ccgaactccg tgctgtttca gcaattttag gggaattaaa tggaaatgaa
     9541 gggaagttga ctgcgtcagt gattgcagat cgtatcggaa tcactcgctc tgtgattgtc
     9601 aatgctcttc gtaaacttga gtctgcgggg attattgaaa gtcgctcact tggaatgaag
     9661 ggaacctatc ttaaggtctt gatttcagat atttttgaag aagtgaagaa aagagattac
     9721 taatgacaaa ggctttaatt tcgattgatt atacagaaga ttttgttgct gatagtggga
     9781 aactaacagc aggtgctcca gctcaggcga tttcggatgc catcagcaag gtaactcgat
     9841 tagcttttga acgaggagat tatatcttct ttactattga tgctcatgaa gaaaacgatt
     9901 gtttccatcc ggaaagtaag ttatttcctc ctcataatct gattgggacg agtggacgga
     9961 atttatatgg agatttgggg aacttttatc aagagcatgg ttcagacagt cgtgtctttt
    10021 ggatggataa acgccattac tcagcttttt cagggactga cctagatatt cgtttgagag
    10081 agcgtagagt gtctaccgtt atcttaacag gtgtcttgac ggatatctgt gtcctacata
    10141 cagctataga tgcctataat ctaggatatg acatcgagat tgttaaacca gctgttgctt
    10201 ccatctggcc tgaaaatcat caatttgccc taggtcattt caaaaataca ctcggagcta
    10261 agttagtaga tgaaaatcta aatgaacttt ctgagtaacc tggttggtga aaatgaaaaa
    10321 atttgaaaaa aagtgttgac aagcatccca aaagttgata tactagtaaa gtaatcgatg
    10381 cggggatggc ggaattggca gacgcgcagg actaaggatc ctgtgaccgc tttaggtcgt
    10441 gagggttcaa gtccctctct ccgcatagga aaagagttag ctaaagctag ctcttttgta
    10501 tttctctaaa aaattagaat ccagtcaaat gtagtggaga atcagcgaaa atatgggaaa
    10561 actgatcctt gtttctgctt ttgtcataga agaataataa agattatctt cttcaaattc
    10621 tccgatattc tctaaagttt tgtgcaagtt gcacagaact tttttatttt tttggtcatc
    10681 ttgccataga aatataaagc gttttcatat ataatataat tatcaaaaga caaaaggagt
    10741 tcacctcatg gtagaattga atcttaaaaa tatttacaaa aaatatccaa acagcgaaca
    10801 ctattcagtt gaagatttca acttgaacat caaagataaa gaatttatcg ttttcgtagg
    10861 accttcagga tgtggtaaat caactacact ccgtatgatt gctggtcttg aagacattac
    10921 agaaggtact gcatctatcg atggcgtggt tgtcaacgac gtagctccaa aagaccgtga
    10981 tatcgccatg gtattccaaa actacgctct ttacccacac atgactgttt atgacaacat
    11041 ggctttcggt ttgaaattgc gtaaatacag caaagaagac attaacaaac gtgttcaaga
    11101 agcagctgaa atacttggat tgaaagaatt cttggaacgt aaaccagctg acctttcagg
    11161 tggtcaacgt caacgtgttg ccatggggcg tgcgattgtc cgtgatgcga aagtattctt
    11221 gatggacgaa cctttgtcaa acttggatgc caaacttcgt gtatcaatgc gtgctgaaat
    11281 cgctaaaatt caccgtcgta tcggagctac aactatctat gtaactcacg accaaacaga
    11341 agcgatgaca cttgcagacc gtatcgttat tatgtcagct actaagaacc ctgctggtac
    11401 aggtactatc ggacgtgtag aacaaatcgg cactcctcaa gaagtttaca aaaatccagt
    11461 taacaaattc gttgcaggat tcatcggaag cccagctatg aacttcatca acgtgaaatt
    11521 ggttggtagc gaaattgttt ctgacggttt ccgtttgaaa gtgccagaag gagcattgaa
    11581 agttcttcgt gaaaaaggct acgaaggaaa agaattgatc tttggtatcc gtccagaaga
    11641 cgtgaatgca gaacctgctt tccttgaaac attcccagac tgtgttgtaa aagcgactat
    11701 ctctgtatca gaactgcttg gttcagaatc tcacctttac tgccaagttg gtaaagacga
    11761 gtttgttgca aaagttgatg ctcgtgacta cttgcaaaca ggtgcaacag ttgagcttgg
    11821 atttgacttg aacaaagcac acttcttcga tgtagaaact gaaaaaacaa tctactaaaa
    11881 taaataaaat tcaaagcact acaagaaaag atatttcttt atcaattgta gtggagagat
    11941 atcagttaat ctagggagag aaacaaaatg cttctctcct ttttgctagg gaagtcatat
    12001 tatgcatcta tattgtgatg ctctttaata ctcttcgaaa atctcttcaa accacgtcaa
    12061 cgtcgccttg ccgtacgtat gattactgac ttcgtcagtt ttatctgcaa cctcaaagct
    12121 gtactttgag cagtttacgg ctagtttcct agtttgctct ttgatttcca ttgagtatta
    12181 tttgtgggta ccatctacaa gtgaagctat atgcgtaaac tacgtgagca attgaattcg
    12241 aactagagag gtaataataa atttatgcta tagttatggt gacttgtatg cttttgattc
    12301 tagtttatca aataatagat tagaattgtc agataatatc attttgtgtt ataatgaaga
    12361 aaaaacagag gtgttcaaat gtcagaagca ggtcataagt ttttagcaaa attggggaaa
    12421 aaacgcttac gtccaggtgg aaagcgtgcc acagattggt taattgcaga aggaggattt
    12481 tcaaaagaaa agagaatact agaggttgcg tgtaataggg gaactacagc aattgagttg
    12541 gcacagcgtt ttggttgcaa gataactgct gttgatatgg atgctcaagc tttagaagtg
    12601 gctaaaaaat ctgctggaac ggcaggtgtt gctcatttaa tcagttttga aagagcaaat
    12661 gcaatgaaac ttccttatca agatgctagt tttgatattg ttataaatga agctatgctg
    12721 actatgcaag ccgatcaagc taagaaaaaa tgtgtaatgg aatatctaag ggtattaaaa
    12781 cctggaggtc ttctcttgac acatgatgta cttcttaagg aagctaaaga gtctatcaga
    12841 caggaattat cacaagcaat tcatgtaaat gtaggtcctt taactcaaga tggttgggaa
    12901 caggtgatga tagaatcagg ttattgtgat gtgaaagcat tgactggtga aatgacatta
    12961 atgaaattat cgggtatgat ttatgacgaa ggtttgctag gaactttgaa aatttgtgta
    13021 aatgcttgta aaaaggagaa tagaaagcag tttttaacta tgtataaaat gtttgctaag
    13081 aataaacaga aattgggctt tattgcgatg gctagttata aatcgtcaaa acgttagata
    13141 attattgaag ttaacttttc cttttttctt tcttaaaaaa tatgctataa tagagagtaa
    13201 aaaactttga aagaaagaaa aagatgaatt taaaagatta cattgcaaca attgaaaatt
    13261 atccaaagga aggcattacc ttccgtgata ttagtccttt gatggctgat ggaaatgctt
    13321 atagctacgc tgttcgtgaa atcgttcagt atgctactga caagaaagtc gacatgatcg
    13381 tgggacctga agctcgtgga tttatcgtgg gttgtccagt tgcctttgag ttgggaattg
    13441 gttttgcgcc tgttcgtaag ccaggtaaat tgccacgcga agttatttct gctgactatg
    13501 aaaaagagta cggtgtcgat accttgacta tgcacgcgga tgccattaag ccaggtcaac
    13561 gtgttcttat tgtagatgac cttttggcga caggtggaac tgttaaggca actatcgaga
    13621 tgattgaaaa acttggtggt gttatggcag gttgtgcctt ccttgttgaa ttggatgaat
    13681 tgaacggccg tgaaaaaatt ggtgactacg actacaaagt tcttatgcat tattaatgaa
    13741 aacagtccct agggctgttt tctctacact aggatataaa aatagactat aactagttag
    13801 agaaaaacta taattgaaaa ctatatcttc ttacagtata ataaaaggac taagtgtttg
    13861 agatttgtct tcaaacatat gcaattattc ctgaaagagt acagttagga gagggttatg
    13921 ccgattcgaa ttgataaaaa attgccagct gttgagattt tacggacaga gaatatcttt
    13981 gtcatggatg atcaacgtgc tgcccaccaa gatatccgtc ctttgaagat tttaatttta
    14041 aatctcatgc cacagaaaat ggtcacagag acccagttgt tgcgccactt ggctaataca
    14101 cccctacaac tggatattga ttttctctat atggagagcc accgttctaa aacaactcgt
    14161 tcagagcaca tggagacctt ctataaaact tttcctgaag tcaaggatga gtattttgat
    14221 gggatgatca tcacgggtgc tccagttgag catttaccat ttgaggaagt ggactattgg
    14281 gaggaattta gacagatgct tgagtggtct aagactcatg tctattcgac ccttcatatc
    14341 tgttgggggg ctcaggctgg gctttatctg cgctatggtg tagaaaaata ccagatggac
    14401 agtaagctat caggtattta tcctcaggac accctaaaag agggtcacct tctatttaga
    14461 ggctttgatg atagctatgt atcccctcat tcacggcaca cggagatttc taaggaagag
    14521 gtcttaaaca agaccaatct cgagatttta tcagaaggac ctcaggttgg ggtttctatt
    14581 ttggccagtc gtgatttacg agaaatttat agttttggtc atttggagta tgaccgtgat
    14641 accttggcaa aagagtattt tcgagatcgt gatgcaggtt tcgacccaca tattccagaa
    14701 aattacttta aagatgatga tgttaatcag gtaccttgtc tttgttggtc ttcatctgca
    14761 gccctctttt tcagtaattg ggtaaaccat gcggtctatc aggagacgcc ttttgattgg
    14821 agaaagatag aagatgatgc atctgcatat gggtatttat aagaggaatt atgacatatt
    14881 tagacgcttt taaatcaggt atcttggttt taccgagtgc cctgctcttg cattttaagg
    14941 aactctttcc ttctagcgac gattttctgg tttggcaatt tttctatttg caaaatacga
    15001 caggcttaga agaaatgtcg ccaagccaga ttgctgaaag gattggcaag gaaatttcgg
    15061 atgtcaacca gtccatttct aatctgacgg aaaggggact gctccagtat cgtactatcg
    15121 aattaaatgg cgaaattgaa ttgctctttg atgctagttt ggccttggaa cgtttggatg
    15181 acctgtttgg agcagttcat tcaagttcag accagctgac acctcaaaac cagctcaagg
    15241 atttggtgga aaccttccag caggagttgg gacgattgtt gacgcctttt gagattgagg
    15301 atttgaccaa gacactaaag gaagatggaa ccagtgctga cttgattaag gaggctcttc
    15361 gtgaagctgt tttgaatgga aaaccaaact ggaagtacat tcaggcgatt ttgagaaact
    15421 ggcgccatga aggaatcaag agtgtggctc aaattgaggc caagagagca gaaagagaag
    15481 caagcaatcc tcagttgaca caggtatctg cagatttcat aaatgccatg gatctctgga
    15541 aggattaatc catgcaagta ggcttgaaat ccgagtaaga tttgcaagct gtgtataatt
    15601 gtgatagaat aaatagaaaa taaattgaaa aaagaggtat gtgaaatgtc acgtaaacca
    15661 tttatcgctg gtaactggaa aatgaacaaa aatccagaag aagctaaagc attcgttgaa
    15721 gcagttgcat caaaacttcc ttcatcagat ctggttgaag caggtatcgc tgctccagct
    15781 cttgatttga caactgttct tgctgttgca aaaggctcaa accttaaagt tgctgctcaa
    15841 aactgctatt ttgaaaatgc aggtgctttc actggtgaaa ctagcccaca agttttgaaa
    15901 gaaatcggta ctgactacgt tgttatcggt cactcagaac gccgtgacta cttccatgaa
    15961 actgacgaag atatcaacaa aaaagcaaaa gcaatctttg cgaacggtat gcttccaatc
    16021 atctgttgtg gtgaatcact tgaaacttac gaagctggta aagctgctga attcgtaggt
    16081 gctcaagtat ctgctgcatt ggctggattg actgctgaac aagttgctgc ctcagttatc
    16141 gcttatgagc caatctgggc tatcggtact ggtaaatcag cttcacaaga cgatgcacaa
    16201 aaaatgtgta aagttgttcg tgacgttgta gctgctgact ttggtcaaga agtcgcagac
    16261 aaagttcgtg ttcaatacgg tggttctgtt aaacctgaaa atgttgcttc atacatggct
    16321 tgcccagacg ttgacggtgc ccttgtaggt ggtgcgtcac ttgaagctga aagcttcttg
    16381 gctttgcttg actttgtaaa ataatcagta agtagcaaaa gctaggtgga acagcattca
    16441 gatgtctgtt acatttttta taggagagga aagattgaaa acaaaaattg gattagcaag
    16501 tatctgttta ctaggcttgg caactagtca tgtcgctgca aatgaaactg aagtagcaaa
    16561 aacttcgcag gatacaacga cagcttcaag tagttcagag caaaatcagt cttctaataa
    16621 aacgcaaacg agcacagaag tacagactaa tgctgctgcc cactgggatg gggattatta
    16681 tgtaaaggat gatggctcta aagctcaaag tgaatggatt tttgacaact actataaggc
    16741 ctggttttat attaattcag atggtcgtta ctcgcagaat gaatggcatg gaaattacta
    16801 cctgaaatca ggtggatata tggcccaaaa cgagtggatc tatgacagta attacaagag
    16861 ttggttttat ctcaagtcag atggggctta tgctcatcaa gaatggcaat tgattggaaa
    16921 taagtggtac tacttcaaga agtggggtta catggctaaa agccaatggc aaggaagtta
    16981 tttcttgaat ggtcaaggag ctatgatgca aaatgaatgg ctctatgatc cagcctattc
    17041 tgcttatttt tatctaaaat ccgatggaac ttatgctaac caagagtggc aaaaagtggg
    17101 cggcaaatgg tactatttca agaagtgggg ctatatggct cggaatgagt ggcaaggcaa
    17161 ctactatttg actggaagtg gtgctatggc gactgacgaa gtgattatgg atggtgctcg
    17221 ctatatcttt gcggcctctg gtgagctcaa agaaaagaaa gatttgaatg tcggctgggt
    17281 tcacagagat ggtaaacgct atttctttaa taatagagaa gaacaagtgg gaaccgaaca
    17341 tgctaagaaa gtcattgata ttagtgagca caatggtcgt atcaatgatt ggaaaaaggt
    17401 tattgatgag aacgaggtgg atggtgtcat tgttcgtcta ggttatagcg gtaaagaaga
    17461 caaggaattg gcgcataaca ttaaggagtt aaaccgtctg ggaattcctt atggtgtcta
    17521 tctctatacc tatgctgaaa atgagaccga tgctgagaat gacgctaaac agaccattga
    17581 acttataaag aaatacaata tgaacctgtc ttaccctatc tattatgatg ttgagaactg
    17641 ggaatatgta aataagagca agagagctcc aagtgataca gacacttggg ttaaaatcat
    17701 caacaagtac atggacacga tgaagcaggc gggttatcaa aatgtgtatg tctatagcta
    17761 tcgtagttta ttacagacgc gtttaaaaca cccagatatt ttaaaacatg taaactgggt
    17821 agcggcctat acgaatgctt tagaatggga aaacccttat tattcaggag aaaaaggttg
    17881 gcaatatacc tcttctgaat acatgaaagg aatccaaggg cgcgtagatg tcagcgtttg
    17941 gtattaagcg atgatttgaa agagggatgt gatagtagca ccctcttttt ctttgtttta
    18001 tgatagttca tcctcgagta aattcaagat cttgctcgga aatgaagctt atatagtaga
    18061 ttgaatatag acaaagacct tgtgattggt aaaacatttt agaaattcat ttacctttcc
    18121 taatcgactt ggtttcatct tatttcaatc tattatagta ttggggaatt tcttcaaacc
    18181 acatcagctt ggtcagttct acctgcgacc tcaaaacttg tgctttggtc aagctgggtt
    18241 tagtttccta gtttgctgat ggatttccat tgactataag catccaaccc tcttttttgt
    18301 cttctaaaga attcttaaat tatcagtcta ttgcaacttt tctcatataa gttctttgtc
    18361 ttgctattag ttttccttag tagtatacta aggtagtaat cattaagaag tggttacaaa
    18421 aaataatgaa tgaggtaaag aaaatggtag aattgaaaaa agaagcagta aaagacgtaa
    18481 catcattgac aaaagcagcg ccagtagcat tggcaaaaac aaaggaagtc ttgaaccaag
    18541 ctgttgctga tttgtatgta gctcacgttg ctttgcacca agtgcactgg tatatgcatg
    18601 gtcgtggttt ccttgtatgg catccaaaaa tggatgagta catggaagct cttgacggtc
    18661 aattggatga aatcagcgaa cgcttgatta cactcggtgg aagcccattc tctacattga
    18721 cagagttcct tcaaaatagt gaaatcgaag aagaagctag tgaataccgt aatgttgaag
    18781 aaagcttgga acgtgttctt gttatctacc gttacttgtc agaacttttc caaaaaggtt
    18841 tggatgtcac tgatgaagaa ggtgacgatg tgacaaacgg tatctttgca ggcgctaaaa
    18901 ctgaaacaga taaaacaatt tggatgcttg cagccgaact tggacaagca cctggtttgt
    18961 aagaaataag gaaacataga taaatctgta ggaaatttct tacagatttt ttctattttg
    19021 taagctattc caaaccagtc tttttttgag ttttttgata aaatagtact atcagtgaaa
    19081 aggatggaag tatgactaag aaaatcgtag ctatttgggc ccaggatgaa gagggtgtga
    19141 ttggtaagga aaatcgtctg ccttggcatt tgccagcaga attgcagcac tttaaagaaa
    19201 caactctgaa tcatgctatc ttgatggggc gtgtgacctt tgatgggatg gggcgtcgct
    19261 tgcttccaaa acgggaaacc ttgattttga cgcgtaatcc ggaagaaaag atagatgggg
    19321 ttgctacttt tcaggacgtc cagtctgttc ttgactggta tcaggctcaa gaaaagaatc
    19381 tctacattat tggtgggaag caaatttttc aggcttttga accttacctt gatgaagtga
    19441 ttgtcactca cattcatgct cgtgtggaag gagataccta tttccctgaa gaacttgact
    19501 tgtctctttt tgagacagtt tcaagcaaat tttacgccaa agatgagaag aatccttatg
    19561 attttaccat ccaataccgc aagagaaagg aactctaatg gaacggagtt tatttggtct
    19621 attcacggct tttctgtgtt tcatctgctt tctggcagga gcacaagctt ttcgtaaaaa
    19681 gcgttacggg ctttctatcc tcctttggtt aaatgccttt accaatctgg tcaatagtat
    19741 tcatgctttt tacatgacct tattttagat agaatgacag tatagaatgg aaggaaatca
    19801 tgtctacaaa tagaaaaaat gatatgatgg tttattgctc attttgtggc aaaaaccaag
    19861 aagaagtaca aaaaataatt gctggcaaca atgcttttat ttgtaatgaa tgcgtggagt
    19921 tagctcagga aatcattcga gaagaattgg ttgaggaagt cttggcagac ttgtctgagg
    19981 tgccaaaacc aattgaactc ctccatatct tgaaccacta tgtaattggt caagatcgtg
    20041 ccaagcgtgc cttggcagtg gcggtttata accactacaa acgcatcaat ttccacgata
    20101 cacgcgaaga gtcagaagat gtagatttgc agaagtcaaa cattttgatg attggcccaa
    20161 ctggttcagg gaaaactttc cttgcccaga ccttggctaa gagcttgaat gtgccttttg
    20221 ctattgcgga tgcgacagct ctgacggagg ctggttatgt gggtgaggat gtggaaaata
    20281 tcctcctcaa actcttgcag gttgctgact ttaacatcga acgtgcagag cgtggcatta
    20341 tctatgtgga tgaaattgac aagattgcca agaagagtga gaatgtgtct atcacacgtg
    20401 atgtttctgg tgaaggggtg caacaagccc ttctcaagat tatcgaggga actgttgcta
    20461 gcgtgccgcc tcaaggtgga cgcaaacatc cacaacaaga gatgattcaa gtggatacaa
    20521 aaaatatcct cttcatcgtg ggtggtgctt ttgatggtat tgaagaaatt gtcaaacaac
    20581 gtctgggtga aaaagtcatc ggatttggtc aaaacaataa ggcgattgat gaaaacagct
    20641 catatatgca agaaatcatc gctgaagaca ttcaaaaatt tggtattatc cctgagttga
    20701 ttggacgctt gcctgttttt gcggctcttg agcaattgac cgttgatgac ttggttcgca
    20761 tcttgaaaga gccaagaaat gccttggtga aacaatacca aaccttgctt tcttatgatg
    20821 atgttgagtt ggaatttgac gacgaagccc ttcaagagat tgctaataaa gcaatcgaac
    20881 ggaagacagg ggcgcgtgga cttcgctcca tcatcgaaga aaccatgcta gatgttatgt
    20941 ttgaggtgcc gagtcaggaa aatgtgaaat tggttcgcat cactaaagaa actgtcgatg
    21001 gaacggataa accgatccta gaaacagcct agaggtgact atggaactta atatacacaa
    21061 tgctgaaatc ttgctcagtg cagctaataa gtcccactat ccgcaggatg aactgccaga
    21121 gattgcccta gcagggcgtt caaatgttgg taaatccagc tttatcaaca ctatgttgaa
    21181 ccgtaagaat ctcgcccgta catcaggaaa acctggtaaa acccagctcc tgaacttttt
    21241 taacattgat gacaagatgc gctttgtgga tgtgcctggt tatggctatg ctcgtgtttc
    21301 taaaaaggaa cgtgaaaagt gggggtgcat gattgaggag tacttaacga ctcgggaaaa
    21361 tctccgtgcg gttgtcagtc tagttgacct tcgtcatgac ccgtcagcag atgatgtgca
    21421 gatgtacgaa tttctcaagt attatgagat tccagtcatc attgtggcga ccaaggcgga
    21481 caagattcct cgtggtaaat ggaacaagca tgaatcagca atcaaaaaga aattaaactt
    21541 tgacccaagt gacgatttca tcctcttttc atctgtcagc aaggcaggga tggatgaggc
    21601 ttgggatgca atcttagaaa aattgtgagg aaaagaaaat ggcaaaaaca attcatacag
    21661 ataaggcccc aaaggctatc ggaccctatg ttcaaggaaa aatcgttggc aaccttttgt
    21721 ttgctagcgg tcaagttccc ctatcccctg aaactgggga aattgtagga gagaatatcc
    21781 aagaacagac agagcaagtc ttgaaaaaca tcggtgctat tttggcagaa gcaggaacag
    21841 actttgacca tgttgtcaaa acaacttgct tcttgagcga tatgaacgac tttgttcctt
    21901 ttaatgaggt ttaccaaacg gccttcaaag aggaattccc agctcgttca gctgtggagg
    21961 tagctcgtct tcctcgtgat gtaaaagtcg aaattgaagt catcgcagag attggataag
    22021 ctagttgaag tttggtgttg ccaaacttct tttgatataa ggagaaaaag atgacaaaga
    22081 aacaacttca cttggtgatt gtgacaggga tgagtggcgc agggaaaact gtagccattc
    22141 agtccttcga ggatctaggt tatttcacca ttgataatat gccgccagct ctcttgccta
    22201 agtttttgca gctggttgaa attaaggaag acaatcctaa gttggccttg gtagtggata
    22261 tgcgtagccg ttctttcttt tcagagattc aagctgtttt ggatgagttg gaaaatcaag
    22321 atggtttgga tttcaaaatc ctctttttgg atgcggctga taaggaattg gtcgctcgtt
    22381 acaaggaaac cagacggagt cacccactag cagcagacgg tcgtatttta gatggaatca
    22441 agttggaacg tgaactcttg gcacctttga aaaatatgag ccaaaatgtg gtggatacga
    22501 ctgaactcac tccacgtgag ctgcgcaaaa cccttgcaga gcagttttca gaccaagaac
    22561 aagcccagtc tttccgtatc gaagtcatgt ctttcggatt taagtatgga atcccgattg
    22621 atgcggactt ggtctttgat gtccgtttct tgccaaatcc ctattatcta ccagaactga
    22681 gaaaccaaac gggtgtggat gaacctgttt atgattatgt catgaaccat cctgagtcag
    22741 aagactttta tcaacattta ttggccttga ttgagccgat tctgccaagt taccaaaagg
    22801 aaggtaagtc cgttttgacc attgccatgg gatgtacggg tggacaacac cgtagtgtgg
    22861 catttgctaa acgcttggcg caggacttat ccaagaattg gtctgttaat gaagggcatc
    22921 gcgacaaaga ccgcagaaag gaaacggtaa accgttcatg agaaaaccaa agataacggt
    22981 gattggtgga gggactggaa ttcccgtcat tctaaaaagt ctgcgggaaa aagatgtgga
    23041 aatcgcagct atcgtgacgg tggcagatga tggtggttct tcaggtgaac tccgaaaaaa
    23101 tatgcaacag ttgacaccgc caggtgatct tcgtaatgtc cttgtggcca tgtcggatat
    23161 gcctaagttt tatgagaagg tctttcagta tcggttctct gaggatgccg gagcctttgc
    23221 tggccatcca ttgggaaatc tcatcattgc tggcttgtca gaaatgcagg gttcaaccta
    23281 taatgccatg cagttattga gcaaattttt ccatacaaca gggaaaattt atccttccag
    23341 tgaccatcct ttgacccttc atgcagtctt tcaggatggg acagaagtgg ttggagagag
    23401 tcatattgta gaccatcgag gcataattga caatgtctat gtgactaatg ctctaaacga
    23461 tgatacgcct ctggccagcc gtcgagtagt gcagaccatc cttgaaagtg acatgattgt
    23521 cctagggcca ggttccctct ttacctctat tttgcccaat atcgtgatta aggaaattgg
    23581 gcgggctctt ttggaaacca aggcagaaat tgcctatgtc tgcaatatta tgacccaacg
    23641 tggagagacg gaacacttta cagatagcga ccacgtggaa gtcttgcatc gtcaccttgg
    23701 tcgccctttt atcgacactg tcttggtgaa tattgaaaaa gtgcctcaga aatacatgaa
    23761 ttccaaccgt tttgatgaat acttggtgca agtggaacac gattttgtag gtctttgtaa
    23821 gcaagtttcg cgcgtgattt catctaactt ccttcgtctg gaaaatggcg gtgccttcca
    23881 cgatggagat ttgattgtgg acgagttgat gcgcattata caggtgaaaa aatgagtttc
    23941 acagtagcag taaaagaaga aatcctgggc caacaccatc tgagccggca tgaattatct
    24001 gccattatca aaatgtctgg tagcatcggt ctctcgactt cgggcttgac tttgtcagtt
    24061 gtgacagaaa atgccaaact ggcccgtcac ctctatgagt cctttctcca tttctatgaa
    24121 atcaaatctg aaattcgtca ccaccaacgg agcaatcttc gcaagaatcg cgtctatacc
    24181 gtttttacag atgaaaaggt gcaggatttg ttaagtgatt tgcacttggc agactctttc
    24241 tttggcttgg aaacaggtat tgatgaggcg attttatcgg atgaggaagc aggtcgtgcc
    24301 tatctctgtg gcgctttctt ggcaaatggg agcattcgtg accctgagtc aggcaagtac
    24361 cagttggaaa tcagttctgt ttatctggac cacgcgcaag gaattgcctc ccttctccaa
    24421 cagtttttac tggatgccaa ggtgcttgag cgcaagaagg gggctgtgac ctatctccag
    24481 cgagcagaag acattatgga cttcttgata gtaatcggag ccatgcaggc acgtgatgat
    24541 tttgagcggg ttaagatttt gcgagaaact cgtaacgacc tcaatcgggc taataatgcc
    24601 gagacagcta atatcgctcg gacagtttct gccagcatga agaccattaa caatatcagt
    24661 aaaatcaaag atatcatggg cttagaaaat ttgccagtag atttgcagga agtggcgcaa
    24721 ctgaggattc agcacccaga ctactctatc cagcagttag cagatagcct cagcacccct
    24781 ctgaccaaaa gtggtgtcaa tcacagactc agaaaaatca ataagatagc cgatgaatta
    24841 taaaaccacg aatcctatgt gactcgtggt tcttttttat aaactagtag agtgttttgg
    24901 ttgtactttt tgttcagggt caatgtagtt gatagcgttg ttgacagcag ttggagcttc
    24961 tccgaggcct gtcgcaatca gatcaatttt tccgtcatag tagcagcagt caccgatagc
    25021 atagatacct gcttggctgg attcctgttt gctgttgacg ataatcttgt gacggttgag
    25081 gtcgagcccc cagtttttaa ggttaccgac agaagatttg aaaccatagt tgacaaagag
    25141 gtggtctagg tcaatggttt cagtttcatc agatttgact tttgtgattt caagtttatc
    25201 aagtgttttt ccatttccaa ggagttggct aggggcgaat ggtgtcttga tggttacaga
    25261 tgattcttgc aaggcttgaa cactgtgttc caaggcacgg aaattatctc tgcggtgaac
    25321 aagggtagtt ggtgcgattt tttcaaaagc caaagcccaa tccacagccg agtctccccc
    25381 accaagaatc gtcactttct taccagcgta ttgctgaatg ttagaaacgt ggtagtggat
    25441 attttcatag ccctcaaccc cttcaagttc cagcggacgt ggtttgaagg caccgccacc
    25501 catagcgatg atgactgttt tagtcaagtg acttccttta gaagttgtga tggcaaattc
    25561 ttcttcttgt ttgtcaatct caagaaccgt ttcattgaga tgaatagggg tatcaaatcc
    25621 atttagctgt tcaatcaagc ggttagtcaa ctcttctcca gtcaggtttg ggaagcctgg
    25681 tacgtctagg atttcctttt cagggtagag aatagcaggt tgtccaccta gctggggaag
    25741 agagtcgatg atttgaacct tggcttggcg taggtgggca taaaaggctg caaaaagccc
    25801 gacaggacca ccacccacaa tggtaatatc atagagttga gacatagttt ctcctttgtt
    25861 ttttctagtc agtttatttt atcatatttt tgttcaatgt aaactggact aggataggga
    25921 aaaaaatgcc agaaaatggt ataataggac gaaagtgttt tgatagggag gatatcaggg
    25981 atgaattttc aacaattatc caatctgcaa tattggacca gtttgtttgc aagtccatgg
    26041 acgatagcta tcaatctgat tgatattttg attgttgctt atattttata ccattttaca
    26101 aaagctattg caggaaccaa gattatgatt ttggtacgtg gagttttggt gtttatttta
    26161 gctcaaatcc ttgcaaatat gattggtttg actacgattt cttggttaat caatcaaatt
    26221 attacttatg gggttattgc ggcggttgtt atcttctctc cagagattcg gactggtttg
    26281 gaacgtttgg gaagagcgac agatttcttt tccaatgccc ctattagtgc tgaggaacag
    26341 atgattcgtg cctttgttaa gtctgttgaa tacatgagtc ctcgtaaaat cggggccttg
    26401 gttgctattc agcgtgtacg taccttgcag gagtatattt cgacaggaat tcccttggat
    26461 gctaagattt ctgcagaact tctcattaac atttttattc ccaacactcc cctacatgat
    26521 ggtgcggtga ttatcaaaga agaacgtatc gctgtgacgt ctgcctatct gcccttgaca
    26581 aaaaacacag ggatttccaa ggaatttggg accagacacc gggcggctat cggtttatca
    26641 gaagtctcag atgccttgac ttttgttgta tcagaggaaa cgggaggaat ttcgataacc
    26701 tataatggaa ggtttaagca caacctaaca cttgatgaat ttgaaacaga attacgtgaa
    26761 atcttacttc caaaagagga agtgggtctt agttttaaag aacgattgct aggaggatgg
    26821 aaacatgaaa aaaaatagtt tatatatcat atcctcactc ttttttgctt gtgtcttatt
    26881 tgtctatgct acggcgacga attttcaaaa cagtaccagt gctaggcagg taaaaacgga
    26941 aacctatact aatacagtaa caaatgtccc tattgacata cgctataata gtgataagta
    27001 ttttattagc ggttttgctt cagaagtatc agtggtcttg actggtgcaa atcgcctatc
    27061 gctagctagt gaaatgcaag aaagtacacg taaattcaag gttactgctg acctaacaga
    27121 tgccggtgtt ggaacgattg aagttccttt gagcattgaa gatttaccca atgggctgac
    27181 cgctgtggcg actccgcaaa aaattacagt caagattggt aagaaggctc agaaggataa
    27241 ggtaaagatt gtaccagaga ttgaccctag tcaaattgat agtcgggtac aaattgaaaa
    27301 tgtcatggtg tcagataaag aagtgtctat tacgagtgac caagagacat tggatagaat
    27361 tgataagatt atcgctgtct tgccaactag cgaacgcata acaggtaatt acagtggttc
    27421 agtacctttg caggcaatcg accgcaatgg tgttgtctta ccggcagtta tcactccgtt
    27481 tgatacaata atgaaggtga ctacaaaacc agtagcacca agttcaagca catcaaattc
    27541 aagtacaagc agttcatcgg agacatcttc gtcaacgaaa gcaactagtt caaaaacgaa
    27601 ttaaaaatag aaaaggattt tataacaatg ggtaaatatt ttgggactga tggagtccgt
    27661 ggagaagcta acctagaact aacaccagaa ttagccttta aactaggacg ttttggaggc
    27721 tatgttctta gtcaacatga aacggaagcg ccgaaagtct ttgtaggacg tgacacacgt
    27781 atttcagggg aaatgctgga atcggccttg gtggcaggtc tcctttcagt agggattcac
    27841 gtatacaaac ttggtgtcct tgcaacacca gcagtagctt acttggttga aactgaagga
    27901 gcaagtgccg gtgtcatgat ttctgctagc cacaacccag cccttgataa cggaatcaag
    27961 ttctttggcg gtgatggctt caaactagat gatgaaaaag aagcagaaat tgaagccttg
    28021 ctagatgctg aggaagacac tcttcctcgt ccaagtgcag aaggcttagg aatcttggta
    28081 gattatccag aaggcttgcg taagtatgaa ggataccttg tttcaactgg aactcctctt
    28141 gatggaatga aggttgcctt ggatacagct aatggagcag cttctaccag tgcccgtcaa
    28201 atctttgcag accttggtgc ccaattgacg gttatcgggg aaacaccaga cggtcttaac
    28261 atcaacctta atgttggttc aacacatcca gaagcccttc aagaagtggt caaagaaagt
    28321 gggtcagcta ttggtttggc ctttgatgga gacagtgacc gcttgattgc tgttgatgag
    28381 aatggtgaca tcgtcgatgg tgacaagatt atgtacatca tcggaaaata cctttctgaa
    28441 aaaggacaat tggctcaaaa tacaattgtg acaactgtta tgtctaacct tggtttccac
    28501 aaggccttga atcgcgaagg tattaacaag gcagttactg cagttggtga ccgctacgtt
    28561 gttgaagaaa tgagaaaatc aggctacaac cttggtggtg aacagtctgg tcacgttatc
    28621 ttgatggatt acaataccac aggtgatggt caattatcag cagttcaatt gactaaaatc
    28681 atgaaggaaa ctggtaagag cttatcagag ttggcggcag aagtaacgat ttatccacaa
    28741 aaattagtta atatccgagt ggaaaacgtc atgaaggaaa aggccatgga agtgccagct
    28801 atcaaggcca tcatcgagaa gatggaagaa gaaatggcgg ggaacggccg tatccttgtt
    28861 cgtccaagtg gaacagagcc cctcttgcgt gttatggcag aagcgcctac aacagaagaa
    28921 gtagactact atgttgatac catcacagat gtagttcgtg ctgaaattgg gattgattaa
    28981 atcctagaaa actagatgaa aataaaaaat tatggtacaa tagcttataa tattgtagcc
    29041 gatggagaaa gacatgaatc ttaaacgtga acaagaattt gttagtcagt atcattttga
    29101 tgcgcgtaat tttgaatggg aaaatgaaaa tggagctcct gaaaccaagg tggatgtgaa
    29161 tttccaattg ctccaacatg accaagaaaa tcaagtgact tccttgattg tcatcttgag
    29221 ctttatgatt gtatttgata agtttgtcat tagtggaaca atctcacaag taaaccatat
    29281 cgatggccgt attgtcaatg aaccaaatga attgaaccaa gaagaggtgg aaaccttggc
    29341 tcgtccatgt ttgaacatgc tcaatcgttt gacttacgaa gtgactgaaa ttgcattaga
    29401 cttaccagga attaatttgg agttctaata tgaaattagc tgttttcaca gattcctctg
    29461 cttatctcag tgcagagacc ttgcaaagag aagacttgtt tgtcttggat attcctgtca
    29521 atattgatgg tgaggaatat gtcgaaggca tcaatctgtc tgctgaggaa ttttaccaaa
    29581 aaatggctca ggcttctgaa ttgcctaaga ccagtcaacc aagtattgcc aagttagatg
    29641 aaatcttaac ttcgctcaaa gaacaaggct atacacatgc cttggggctt ttcctatctt
    29701 ctggaatttc aggtttttac caaaatatcc agtatatggt cgatgactat gagggcttaa
    29761 ccattgcttt cccagacact ttgattacaa gtgctcccct aggcatcatg gttgaaagcg
    29821 tctttaattg gcgtgatcag ggcgatgatt ttgccagcat tcaggataag ctagccattc
    29881 aaatcagccg tacgtcagcc tttatcatgg tagatgactt ggatcatttg gtaaaaggtg
    29941 gacgtctttc aaatggggct gccattttgg gcaatttgct tagcattaag ccaatccttt
    30001 attttaacga tcaaggtgtg attgaagttt acgaaaaagt tcgtactgaa aagaaggcca
    30061 ccaagcgctt aattgaaatt atcaaggaaa caacggcttc aggtcaatac cgggtcattg
    30121 tcattcatgg gaatgctcct gaaaaggctg aagaattgcg tcagcatttg cttgattttg
    30181 gcttgggttc ggatgtttca cttgctacat ttggtagtgt cattggaacg cacctaggag
    30241 caggaagtat tgctctgggt tatattccag tgatttagtt ggcgcttcta ggctagttaa
    30301 gatgccttgt atcttagcaa ttgaacacgg actacctgct tcttgaaaaa agatgcctgt
    30361 cttgcctttc gtggaaagtc agtgccattc cctatttttc aggggcagct aaggtccttt
    30421 gtatcttgat aattgaacac gcctggaacc ctgtgtgaaa aagatagttc ttccaagaag
    30481 tagacacttc ttgattggaa ttcctatttt cactttgtgt tcttacggac tttgtatctt
    30541 agacaggagt agagatgagt attcgagtaa ttattgccgg ttttaaggga aagatgggcc
    30601 aggctgcttg tcagatggta ttgactgatc cagacttgga cttggtagca gttttggatc
    30661 cttttgagtc tgagtcagaa tggcagggta ttcctgtttt caaggataag gctgatttag
    30721 cttgttttga agcggatgtc tgggtagatt ttactactcc agctgttgcc tacgaaaata
    30781 cacgttttgc tcttgaaaat ggctttgctc cagtagttgg aacgactggt ttcacgagtg
    30841 aagaaattgc agagctaaaa gaattttctc gtacccaaga cttgggtggc ctgattgccc
    30901 ctaactttgc cttgggtgct gtcttactca tgcaatttgc gacgcaggct gccaaatatt
    30961 tcccaaatgt ggagattatt gagctccatc atgacaagaa aaaggatgct ccgagtggaa
    31021 cagccattaa aacagctgag ttgatggcag agattcgaga gtcaattcag caaggtgcag
    31081 cagatgagga agagctgatt gctggtgctc gtggtgctga ctttgatggt atgcgcatcc
    31141 actcagttcg tttgccaggt ttggtagccc atcaggaagt catctttggc aatcaaggag
    31201 aaggattgac cctccgtcat gactcctatg atcgcatctc cttcatgaca ggagtcaatt
    31261 tgggaattaa agaagttgtc aagcgtcatg agcttgtcta tggattagaa cacttattat
    31321 gagattaatg caaatgcctt ctgaatttca gaaggcttta ccagtattag aaaaaattaa
    31381 agaagcaggc tttgaggctt attttgttgg gggctctgtt cgagatgccc ttctccatag
    31441 ccctatccac gatgtggata ttgcgacgtc ttcttatcca gaagagacca agcagatttt
    31501 tccgcgaaca gccgatatcg gaatcgagca tggaaccgtc ttggtcttag atggggatga
    31561 ggagtatgag gtaacaacct ttcggacaga ggatgtctat gtggactatc gcagacccag
    31621 tgcggtttcc tttgtgcgct cgctagaaga agacctcaaa cgccgtgatt tcacagtcaa
    31681 cgcctttgcc ttggatgaga caggagaaat cgttgacttg ttccatggtt tagaagattt
    31741 ggaaaagcaa gtcttgcgag cagttggagt ggctagtgag cgtttcaacg aagatgcttt
    31801 acggattatg cgtggtttcc gttttcaggc tagtcttggt tttgcacttg aaccagaaac
    31861 atttaaagct atgaagacct tgacgccgct tttggagaac atttctgtag agcgtacctt
    31921 cgtcgagttt gataaactct tgctggctcc attttggaga agggggttgg cttccatgat
    31981 tgagagtcaa gcttatgact atctccctga tatggcatct agccaggaca agctcaacag
    32041 actgtttgat ttggagactg attttacttt tgaatcctct gaacaagcct gggcggcttt
    32101 actatgggct ttggagattg aaaatgcgca gtcatttttg aaatcttgga agacctcacg
    32161 ccagtttgcc aagcaagttc aggatttgct gattattttg gctctgcgtg aaaatggaga
    32221 attgagcaag cgagattgtt atcgctttga catagatttg cttttacagg ctgaaaatct
    32281 tcgtcaagct caaggaaaag aagtcaaccc acaagccatc acagaaaaat accaaagctt
    32341 gactatccat gacaagaaag agattcagat taatggcggt attttgatca aggaatatgg
    32401 ctatcagcca ggcccagact tgggagagat tttaacagag attgagtttg ccattgtcga
    32461 tggagaattg gagaataatc gtgaagccat ccatgcttac ctgagggaga aaaaatgagt
    32521 gattttatcg ttgaaaaact aagtaaatct gttggtgaca agaccgtttt tagggatatt
    32581 tcctttatta tccatgactt agacagaatt ggtttaatcg gtgtcaatgg gactggcaag
    32641 accacccttt tggacgtcct ttctggtgtt tctggctttg atggggatgt cagtcctttt
    32701 tcagctaaaa atgattacca gattggttac ttgactcagg atcctgattt tgatgataga
    32761 aagacagttt tggatacgat tctatctagt gaactcaagg aaatccagct cattcgtgag
    32821 tatgaattga ttatgctcga ctatagcgag gacaagcagg cgcgtttgga acgtgtcatg
    32881 gcagagatgg actctctcca agcttgggaa atcgagagtc aggtcaagac cgttcttagc
    32941 aaattgggca ttcaagactt atctactcct gttggggaat tgtcaggtgg tctgagaaga
    33001 cgggtacagt tggcacaagt cttacttggc aaccacgacc tcttgctttt ggatgagccg
    33061 accaaccatc tggatattgc gattattgag tggctgaccc tctttttgaa aaattctaag
    33121 aagaccgtcc tttttatcac tcacgatcgt tatttcttag acgctttgtc aacacggatt
    33181 ttcgagttgg agcgagcagg cttgacagaa tatcagggca attaccagga ctatgttcgc
    33241 cttaaggcag aacaggacga gcgcgatgca gctctacttc ataaaaaaga acaactctac
    33301 aaacaagaac tggtctggat gcgcagacaa ccgcaggcac gtgcgaccaa gcaacaagct
    33361 cgtatcaatc gtttccatga tctgaaaaag gaagtttcag gcagtagtgc tgagacagac
    33421 ttgactatga actttgaaac cagtcggatt gggaagaaag tcatcgagtt tcaggctgtt
    33481 tcctttgcct atgaaaataa gcccattttg caagatttta atctcttagt tcaggctaaa
    33541 gaccgtattg gaattgttgg ggacaatggt gttggaaaat caaccctact taacctgatt
    33601 gcaggaagtc ttgagccgac agcaggacaa gttgtgattg gggaaactgt tcgcatcgcc
    33661 tatttctctc aacaaattga gggtttggat gaaagcaagc gtgtgatcaa ttacctgcag
    33721 gaagtggcag aggaggtcaa gaccagtggt ggttctacga cttccatcgc tgagttgctg
    33781 gagcaattcc tcttcccacg ttcgacgcat gggaccttga ttgagaaatt gtcagggggt
    33841 gagaaaaaac gtctttatct cctcaaactg cttttggaaa aaccaaatgt tcttctttta
    33901 gacgagccaa ccaatgacct agatattgca actttgacag tcttagagaa tttcttgcaa
    33961 ggttttgcag gtcccgtttt aacagtcagt cacgaccgct atttcttgga taaggtagcg
    34021 accaagattc tcgcttttga ggatggcaag attcgtcctt tctttggtca ttacaccgac
    34081 tatcttgatg aaaaagcttt tgaaacagat atggccaatc aagtgcaaaa ggccgaaaag
    34141 gaaaaagtgg tcaaggttcg agaagacaag aaacgcatga cctaccaaga aaagcaggag
    34201 tgggcaagta ttgaaggtga tattgaaacc ttggaaaaac gtatcgctgc tattgaagag
    34261 gaaatgcagg ctaacggctc tgactttggt aagctggcta ctctccaaaa agaattggat
    34321 gagaaaaatg aagcactcct tgaaaaatac gaacgctatg agtatctcag tgaatttgat
    34381 agttaatact attcgaaaat caaagtgtaa actatgtcgg cttcacattg ccgactcaag
    34441 tacagcctgt ggccggcttc ctagtttgca ctttgatttt tattgagtat aaaagaatag
    34501 aaaaatccca tctcatgaac ggatttctct attctttttt ggtttcttga tgaaagatat
    34561 tttgccaggt ttcgtggcga cgccagatac tggtatggat gataccatct aactcatagc
    34621 agatgagttt ggttttttga ctgatggaag taatttgaat gtccttgata gcagaattta
    34681 actctttttt ggtcttataa gcctctttat ccatctgctc tccatcttgg cgaatataga
    34741 caaaatcatc agtcaagagt tcttctagtt ggtttccttg gtcaatcaat tgttcacgca
    34801 taagcaattt tttatagaca ttgtctaaaa tttcatcctc agggataggt gctggttcga
    34861 tatggacatc ggtatcaaag acgccaaaac gattctccag catagactcg acctgatccg
    34921 cgatttcatg gctttcaaaa acagacaagt caggattcat ctctagtgta atatccaggt
    34981 agatgttgct accgtaggtg cgacctcttt gcgatttgac cttgctgatt ttgggaattt
    35041 ccatgatagc cttttggtag tcctcgagca ggcggtcgtc aaagccatct gaaagactaa
    35101 aggaagactc gatgaagata tcataggcag tcttcaagat aaagaaagtg atgatgatag
    35161 caaccagttt atccacaatc ggataattga aactactagc taggatggca atggcggttc
    35221 caagtgaggt aacagcgtca gaaagattgt ccttagcagc tgctttcagc gccttggagt
    35281 tggatttctt actgaggcga gtattgtaga gatagaccac aaacataatc gctgcagaaa
    35341 tgattcctag agttgcacca agaggatcaa tgaccgtttc ttcccgactg agaatctttt
    35401 gaatggtatc tcttagaaca tcgaaaccga catagaacat gatgatagaa gtgatcaagc
    35461 ttgccaaatc ttcaatcttc caatgaccaa aacggtggtc acggtctgca ggctggcgcg
    35521 ccatccgaat cccgattaag agggccacat ttccaatgat gtccgatacg ttattaaaac
    35581 catcggccac caaactggat gaatgaagga gatgaccagt tgctaatttg gctgcagaca
    35641 agatcaaata ggtcgaaata ctgataatgg ctccacgctc agctaacttg agatttgaga
    35701 tagattgctt cattcaactt cctttctagt cacatagcat tctaccatta tactggtttt
    35761 caaggaaaaa ttcaaataag gcagttttta ctctttgaaa actccccaaa atttggtata
    35821 atagtactac tcaagggagt agctggcaga aacctgtgat agtgtcgtca ttccgaattt
    35881 tatgctgaaa agtatgcttt ccggccctat cttaaacagc gagacttgtt atgattaaca
    35941 ggtctctttt tgtttgtcgt gaaaagatat gacagaaaga gagtctgttt tgcacacaat
    36001 gtcaaggagg agacacatgt caaaagaaca aaaacgccaa gcgttttata ctcagagccc
    36061 tgaagaggtc ttgcaggctg tggatgcgac cgagcaaggt ttgtcgtcaa gtgaggcgga
    36121 aaagcgcctt gtcgaatttg ggcacaatga actcgaagaa ggcgagaaac gatcaatctt
    36181 ggtcaaattc atcgagcaat ttaaggattt gatgattatc atcctagttg cggcagcaat
    36241 cttgtcagtc gtgacttctg gtggggaaga tatcgcagat gccattatca tcctagctgt
    36301 ggttatcatc aacgctgcct ttggtgttta ccaagaagga aaagctgaag aagctattga
    36361 agccctcaaa tccatgtcta gtccagttgc ccgcgttctt cgtgatggac acatggcaga
    36421 gattgactct aaagaattgg taccaggcga tatcgttgcc cttgaagcag gtgacgtggt
    36481 accagcggac ctacgtttga tagaagccaa ctctcttaaa attgaagaag cagccttgac
    36541 aggtgaatct gtaccagtcg aaaaagactt gtcagtcgag cttgcgacag atgctggtat
    36601 tggtgaccgt gtcaacatgg ccttccaaaa ctcaaacgta acctatggtc gtgggatggg
    36661 tgttgttgtc aatacaggta tgtacactga agttggtcat attgctggta tgcttcaaga
    36721 tgcggatgag actgatacac cactcaaaca aaacttgaac aacctttcta aggtcttgac
    36781 ctatgctatc ttggccattg cccttgttac ttttgtagtg ggtgtcttca ttcaagggaa
    36841 aaatccactt ggtgagttgt tgacttctgt tgcccttgcc gttgcagcca ttccagaagg
    36901 acttcctgct atcgttacca tcgttctttc tcttggtact caagttttgg ccaaacgaca
    36961 ttccatcgtt cgtaagttgc cagcagttga aacacttggt tcaactgaaa tcatcgcttc
    37021 tgataagact ggtacgctga ctatgaacaa gatgacagtc gaaaaagtct tctacgatgc
    37081 ggttctacat gactcagctg atgatattga actaggtctt gaaatgccac tacttcgttc
    37141 agttgtcttg gccaatgata cgaaaatcga tgtggaaggt aacttgattg gtgacccaac
    37201 cgaaacagcc tttatccaat atgccttgga caagggctat gatgtcaaag gtttcttaga
    37261 gaaatatcct cgtgtagctg aattgccatt tgactctgac cgtaagctca tgtcaacagt
    37321 tcacccattg ccagatggtc gtttccttgt agcagtcaag ggtgcgccag accaactctt
    37381 aaaacgttgt cttcttcgtg ataaggctgg ggatattgct ccgattgatg agaaggttac
    37441 aaatctcatt catacaaaca attctgaaat ggctcatcaa gccttgcgtg tccttgcagg
    37501 tgcttataag attatcgata gtattccaga aaatctcact tctgaagagc ttgaaaatga
    37561 tttaattttt actggtttga ttgggatgat tgaccctgaa cgtcctgaag ccgctgaggc
    37621 tgttcgtgtg gctaaggaag cgggaatccg tccaattatg attacaggtg accaccaaga
    37681 cacagcggaa gccattgcca aacgtttggg aatcattgac gcaaacgata cagaaggtca
    37741 cgttttaact ggtgctgaac tcaatgaact gtcagatgaa gaatttgaaa aagtcgttgg
    37801 tcaatactct gtttatgccc gtgtgtctcc agaacacaag gttcgtatcg tcaaggcttg
    37861 gcaaaaacaa ggtaaagtcg ttgccatgac aggtgacggt gtcaatgacg cgccagctct
    37921 gaaaacagcc gatatcggta tcggtatggg aatcactggt acagaggttt ctaagggggc
    37981 ttctgatatg attcttgcag atgataactt tgcgactatt atcgtcgcag tggaagaagg
    38041 acgtaaggtc ttctcaaaca ttcaaaagac tattcagtac ctactttctg ctaatactgc
    38101 tgaagtatta accatcttcc tatcaacctt gtttggttgg gatgtcttgc agccggttca
    38161 tcttttgtgg atcaacttgg taacggatac cttcccagct atcgctcttg gtgttgaacc
    38221 tgcggagcct ggtgtcatga atcataaacc acgtggacgc aaggcaagct tcttctcagg
    38281 tggtgttttg agttctatca tttatcaagg tgtactccaa gcagctcttg ttatgagtgt
    38341 ttatggcctt gcgattgctt acccagttca tgtgggtgac aatcatgcta ttcatgcaga
    38401 tgccctaacg atggcctttg caacccttgg tttgattcag ctcttccatg cctacaatgt
    38461 caagtctgtc taccaatcca tcttgacagt tggcccattc aagtctaaga cctttaactg
    38521 gtccatcttg gtatctttta tccttctcat ggcaacaatc gttgtagaac cgcttgaagg
    38581 aatcttccac gtaaccaaac tagacttgtc acaatgggga attgttatgg ctggaagctt
    38641 ctcaatgatt atcatcgtcg aaatcgttaa gtttattcaa cgcaaactcg gttttgacaa
    38701 gaatgcgatt taagggaggt ttcggatgtc agcatatcaa ttaccgaccg tatggcagga
    38761 tgaagctagt aatcaaggag cttttacggg gctaaacaga ccaacagcag gtgcccgttt
    38821 cgaacaaaac ttgccaaaag gagaacaagc ttttcagctt tattcactgg gaacaccaaa
    38881 tggtgtgaag gttactatct tattggaaga attactagaa gctggtttta aggaagcggc
    38941 ttacgacttg tataagattg ctatcatgga tggggatcaa ttcggctcag actttgtgaa
    39001 gctcaatcca aattccaaga ttccagcctt attggaccag tcaggtactg aaaacgtaag
    39061 agtctttgag tctgctcata ttcttcttta ccttgctgag aaatttggag cctttttacc
    39121 aagtaatcct gtggaaaagg tagaagtttt gaattggcta ttctggcaag caggtgcagc
    39181 accttttcta ggtgggggat ttggacattt cttcaattat gctcctgaaa aattggaata
    39241 tcctattaac cgttttacga tggaagtgaa acgccagttg gatttattgg ataaggaatt
    39301 ggctcagaaa ccttatattg caggcaatga ctatacgatt gcagatattg ctatctggtc
    39361 ttggtatgga cagttagttc aaggaaatct ttaccaaggt tctgcaaaat tcttggatgc
    39421 ctcaagttat caaaatctag taaaatgggc agaaaaaatt gccaatcgtc cagctgttaa
    39481 gcgtggattg gaagtaactt atacagaaat taaatagcaa aaaagtcatc ttcggatggc
    39541 tttttgctac agttgaggga aagggtttgc agttatcggc ttttgtgcta taattgctat
    39601 aatatagtaa aaagcaagag gagtgtgagg aagtggaaaa gaaaattgtg aaggatatct
    39661 tatttttatc tcaagtgtct cagccggcaa gtcaggagga cctttatctt gccagagatt
    39721 tgcaggatac actcttagca aatcgtgata cctgtgttgg tctagctgcc aatatgattg
    39781 gggtgcagaa gcgcgtgatt atctttaatc ttggcttggt tcctgtggtc atgtttaacc
    39841 cagtgcttct gtcctttgaa ggatcctatg aggcagaaga aggctgtttg tccttggtag
    39901 gtgtgagatc aactaagcgt tatgaaacca taaggcttgc ctatcgtgac agcaagtggc
    39961 aggaacagac cattaccttg acaggcttcc cagctcagat ttgccagcat gagctggatc
    40021 acttggaagg acgaatcatt taggaggaaa gcaaatgaaa cgaatagtct ttgaacttat
    40081 ttttatcgca acgacctggt atatcttttt accgcccctt aacctgacca gctgggaatt
    40141 tctcttcttc ctctgtgggc atttgttagt tgtggcaata ttatttggct ttggcaaggg
    40201 gataaacctt gtcaaaacgg ttcatgtgcg ccacggtaag gcggaagctg ccttaaatct
    40261 tgagggtttc aaaatcaatc ggttagggaa aattctgtta gcttcgattg gaggaattct
    40321 tctcttggca gctttggttt ccttggtaac ttccagcatg tttcaggcta aaaattatgc
    40381 caatgtagtc acggttacgg aaaaagactt tactgaattt cctaagagtg acaccagtaa
    40441 ggttcctatc ctagatagaa gtactgctga aaaaattgga gaccgctact tgggttccct
    40501 aaccgataag gtgtcgcaat acgtagcggc agatacctat acccaattga caattgatgg
    40561 gaaaccttat cgggtcacac cactagaata tgcagaccct atcaaatggt ttaacaatca
    40621 agccaaggga atcggtgagt atattaaggt ggacatggta actggaaatg cggatttggt
    40681 ggacttgaag acaccaatca agtattcaga ctcggagtat tttaaccgtg atgtcaaacg
    40741 tcacctgcgc ttgaagtacc cgaccaaaat ctttaaaact ccatcttttg aggtggacga
    40801 tgagggcaat cctttctatg tagcaacggt ttaccaaaag caatttggac ttgctgttcc
    40861 tcgtcctgct tcagtcatta tcttggatgc tacaaatgga gaaaccaagg aatacagctt
    40921 atcagatgtt ccagaatggg tggacaggat ctatccagca gaggaaacca ttgagcaaat
    40981 caactacaac ggcaagtaca aggacggttt cttgaatgcc atgatttcca agaaaaacgt
    41041 gacccagact accaatggct ataattactt gtctatcggt aatgacatct atctctacac
    41101 aggtgtgacg tcggctaatg cggatgagag taatcttggt ttcatccttg aaaatatgcg
    41161 aacaggagaa atcactaagt atagcttggc ttctgcgaca gaagaatcag cccgtgaatc
    41221 agcagaaggt gctgttcagg agaaatccta caaagcaacc ttcccaatcc tcatcaacct
    41281 caatgacaag cctctctaca tcatgggctt gaaggacaat gctggcttgg tcaaagagta
    41341 cgccctggta gacgcagtcg agtaccaaaa tgttatcgtt gctactacag tggaagagat
    41401 gctcagcaag tatgccaata aaaacgacct tgaaattgac aatgcaacga cagaaagcat
    41461 caatggagta gtagcagacc tcaaatcagc tgttatcaag ggagacactg tctacttctt
    41521 taaagttgat ggcaagatat acaaggtcaa ggcttcagta tccgatgacc ttccttacct
    41581 tgaaaatggt aaaaccttcg aaggtcaagt aggaaaagac aattatctca agacctttaa
    41641 gctacggtaa aaataggttt ttttcagaaa gtatatgtta taataaggta aattaagcct
    41701 aatggaggac aaagaaatgg gtttttattt gatggttgct tcaatgctac tcggactgct
    41761 cgctttgaag ataggttttt ctcagttcaa ggagaaaaaa gataaattct tatctatctt
    41821 aacaagttta gctggcacag cccttgttct cgtggctgtc tggttaggat ggcccaaata
    41881 aatagaaaaa cctcggtcaa accgaggttt ttcaaatgaa tttcttggtt gtggctaaaa
    41941 aatatgctac actatcaata tgaaaatttt aatcccaaca gcaaaagaaa tgaacacaga
    42001 cttgccaagt atcgaggcaa ttcctttaaa accagaaagt caggccgtgc ttgatgcctt
    42061 ggctctctat tctgccagtc aattggagag tttctacaag gtatcagctg agaaagcggc
    42121 ggaagaattt caaaatatcc aagctttgaa aaggcaaact gctcaacact atccagcctt
    42181 gaaacttttt gatgggctta tgtaccgcaa cattaagaga gataagctga ccgaggcgga
    42241 acaagattat cttgaaaatc atgttttcat tacctcggct ttgtacggtg ttgttccagt
    42301 cttgtcaccc atggctcctc accgtttgga ttttttgatg aaattaaaag tcgctggtaa
    42361 gactttgaag agccattgga aggcagccta tgatgaaact ctgaagaagg aagaagtgat
    42421 tttctctctc ttgtcatcag agtttgagac tgtattttct aaggaaatca gagcaaagat
    42481 ggtgacctta aaattcatgg aggatagagg cggtcagctg aagattcact caactatctc
    42541 caagaaagcg cgcggggcct ttctaacagc tttaatagaa aatcaagtac aaactgtggg
    42601 ggaagcacgt cgcttgaact ttgctggatt tgtttaccga gaagatttgt cacaaccaca
    42661 gggattggtt tttgtaaagg aagtatagaa atcagatatt ttgtatttgg caatatgtat
    42721 catcagctat tttagtttat aaatgagaaa aaagcgaaca agctagtctt ctgagtgtca
    42781 gaaaagtagt cttgttcgct tttattatgt tatactcttc gaaaatctct tcaagccacg
    42841 tcagtgtcgc cttaccgtat atatgttact gacttcgtca gttctatcta caacctcaaa
    42901 gcagtgcttt gagtagcttg cggctagctt cctagtttgc tttttgattt ttattgagtg
    42961 ttagttactt gatagcttcg accaagtctt gagcttgttt ttcaagtgag tttaggactg
    43021 tttcttcaag aaccaatttt ccgtctgccc aggcagagtc attaacacgt gcagcagtga
    43081 aatcaccaac gccttgtgta cggataaatg gcaagaggtc tttgtagata gcgaaaagtt
    43141 gatcgtgccc tgcattggct acagatgata ctgtgacaaa cttgtcttga agggcagaaa
    43201 cgccacgtgt atcagacaag tcaagggcac gagatagcca gtcaagcaag tttttcactg
    43261 taccagggat agagaagttg tagactggag agaaaatcca gatagcatcc gcaacgagaa
    43321 ctgcttcacg agcagcagct acagctggat gtgttggaac ttccaaatct tggctgaaga
    43381 gaggaagggc tgaataatca aggtagctaa cttccgcttt accagcaagt gctttctcag
    43441 cttcgagcgc catttggtgg ttgaaagaac cttgacgtag tgatccgacg ataaataata
    43501 cttttttaga catgatgtgt ctcctttttc ttaaaatttc gagaactctc tcgttgttat
    43561 aaaatatatt acaacaaaac aaaagaactt gcaagaaatt tgctcagagt ttatttgaaa
    43621 attgtaaaat ttcggaaact ctagtcattt gtgactgaaa aagtaagaac tgtttcactt
    43681 tcaaaatcgg ttttgtttga agggagaaat agaattggtt gctcaaagca cagctttgag
    43741 gttgcagata aagctgacgt ggtttgaaga gattttcgaa gagtattctt atattcactt
    43801 gtaataaagc ttaatagatg gtaaaataga cgagtgaaaa aaagacaaaa caaagcaaaa
    43861 aataatctac tgtggcagta tggtctaggg atgacgattt tgtttgtggt tatcagtgct
    43921 tcctttctgt atatggtttc tcttagcatg aaaccctatc aaacagctaa aagtgaagga
    43981 gaaaaattag ctcagcagta tgcaggatta gagcaggccg atcaggttga tttatacaat
    44041 ggcttggaat cttattacag cgttcttggt cgtaataaac agcaagaagc acttgctgtt
    44101 ctgattggaa aagatgatca taagatttac gtttatcagc taaatcaggg tgtttcacaa
    44161 gaaaaagcag aaacggtttc taaggaaaag ggagctggcg aaattgacaa gattatcttt
    44221 ggtcgttatc aagataagcc aatctgggaa gtcaagtcag gatctgattt ttatctagta
    44281 gattttgaaa caggagcatt ggtcaacaag gagggcctat gaaattatcc aaccgtgttt
    44341 tagaaatgga agaaagtgtg actttggctg ctggagcccg tgccaaagca ctgaaggctg
    44401 agggcagaga tattttgtct ctaaccttgg gtgagccaga tttcactact cccaaaaata
    44461 tccaagatgc cgccattgca tcgattcgag atgggcgtgc ttctttttat acagtaacct
    44521 caggtctgcc agagcttaag gcggcggtca atagctactt tgagcgcttt tacggctatt
    44581 ctgtagcgtc aaatcaagtg acagtcgctg cgggagccaa atattctctc tataccttct
    44641 ttatggctgt ggtcaatcca ggtgatgaag tcatcatccc aaccccatac tgggttagct
    44701 atggagatca ggtcaagatg gcagaaggcg ttcccgtctt tgtttctact aaggaagaca
    44761 atcactttaa ggtgaccgta gatcagttag aagcagctcg cactgacaag accaaggttt
    44821 tggtgctgaa ttcgccatct aatcccacag gtatgattta cacccgtgag gaactcttgg
    44881 caattggaaa ctgggctgta gaaaatgata ttctcatcct agcagatgat atctatggcc
    44941 gcttggttta taatggtcat gagttcacac cgatttctag cctatcggaa gcgattcgca
    45001 agcaaacagt ggtcatcaat ggtgtgtcta aaacctatgc catgactggt tggcggattg
    45061 gttatgccgt tggagaagca gacattatcg ctgccatgtc caagattgca ggtcaaacaa
    45121 cttcgaatcc gtcagcagta gcccaatatg cagcagttga ggctctatca ggtgagcaag
    45181 atactgtaga aagcatgcgt caggcctttg aggaacgtct taatactatc tatcccctcc
    45241 ttgcagaggt gccaggattt gaagtggtca aaccgcaagg ggccttctat ctcttcccaa
    45301 atgtcaaaaa ggccatggag atgaaaggct acacggatgt gacagacttt acaactgcta
    45361 tcttagaaga agccgaagtg gccttggtaa caggagctgg atttggagca ccagaaaatg
    45421 tccgcctcag ctatgcgaca gacctagaca cgcttaaaga agcagtcgaa cgcttgaaag
    45481 catttatggg tagtgagaat gattgatcat tttgagatta aggtaaagga tttacaaatt
    45541 tcagaaggat tttataggag ttttctcgct cctttggact ataaaatggc ttttaagact
    45601 agttctctaa ttagttttct atccccgaac agccctcatc ctggtggtga tttttggctg
    45661 actcagggaa cacaagatcc tgttcatttt gcttttttag cagaaaataa ggaagaagtt
    45721 caggcttgtt atgaggctgg cttagaggca ggtgggcgag acaatggggt tcctggttat
    45781 cgaagtgagc atccgattta ttatgctgct tttatgattg acctggatgg gaacaatata
    45841 gaggtggttt gccataaaga ataaaaaaga aaaggaaaaa taatgacaaa acgtgtaacg
    45901 attattgatg taaaagacta tattggtcaa gaagtgacga ttggcgcttg ggttgccaac
    45961 aaatcaggaa aagggaaaat cgctttctta caattgcgtg atggaacagc cttctttcaa
    46021 ggtgtggctt ttaaaccaaa ctttgtcgaa aaatttggtg aagaagtggg acttgagaag
    46081 tttgatgtta tcaaacgctt gagccaagaa acgtctgttt atgtgacagg tattgtcaaa
    46141 gaggacgaac gttctaaatt tggctatgag ttggacatca cagacatcga agtgatcggt
    46201 gaatctcaag actacccaat cacaccaaaa gaacacggaa cagacttttt gatggataac
    46261 cgtcacttgt ggctacgctc tcgtaagcaa gtagctgtgt tgcaaatccg taacgctatt
    46321 atctatgcaa cttatgagtt ctttgacaag aacggtttta tgaagtttga cagcccaatt
    46381 ctttcaggaa atgcggcaga agattctaca gaactctttg aaactgacta cttcggaacg
    46441 ccagcctact tgagccaatc aggtcaactt tacctagaag caggggctat ggctcttggt
    46501 cgtgtctttg actttggtcc agttttccgt gctgaaaaat caaaaacacg ccgtcacttg
    46561 actgagttct ggatgatgga tgctgagtac tcatacttga cacatgatga gtcgcttgac
    46621 ttgcaagaag cttatgtgaa agctcttcta caaggtgttc ttgaccgcgc gcctcaagcc
    46681 ttggaaacct tggaacgtga tacagaactc ttgaaacgct acattgcaga gccattcaaa
    46741 cgtatcactt acgatcaagc cattgacctc ttgcaagagc atgaaaatga tgaagatgct
    46801 gactacgagc atcttgagca tggtgatgac tttgggtcac cacacgaaac ttggatttca
    46861 aaccactttg gtgtgccaac atttgtcatg aactatccag cagccatcaa ggctttctac
    46921 atgaaaccag ttcctggaaa tccagagcgc gtgctttgtg cagacttgct tgctccagaa
    46981 ggctatggag aaattatcgg tgggtctatg cgtgaggaag attacgatgc ccttgtcgct
    47041 aagatggatg aacttggcat ggatcgtaca gaatatgaat tctaccttga ccttcgtaaa
    47101 tacggtacag ttccacacgg aggatttggt atcggtatcg aacgtatggt aaccttcgca
    47161 gcaggaacaa aacatatccg tgaagctatt ccattcccac gtatgttgca ccgtatcaaa
    47221 ccataagaac aggaaaacgc ccatgtggcg ttttttcgaa ttctagtgtt tttacttgcg
    47281 taaaaaaatt ttttctagta taatagttta ttgtgagcga acctcactta ccccttgcaa
    47341 agtcttgggg tcattagacc aaaaggagga acatatcaat ggctaaatac gaaattcttt
    47401 atatcattcg tccaaacatt gaagaagaag ctaaaaacgc tttggtagca cgttttgact
    47461 ctattttgac tgacaacggt gcaactgttg ttgaatcaaa aacttgggaa aaacgtcgtc
    47521 ttgcatacga aatccaagat ttccgtgaag gactttacca catcgttaac gttgaagcaa
    47581 atgacgatgc agctcttaaa gagtttgacc gtctttcaaa aatcaacgct gacattcttc
    47641 gtcacatgat cgtcaaaatt gacgcgtaag aaggtaaact atgattaaca atgttgtact
    47701 tgtagggcgt atgacacgtg acgctgagtt gcgttatacc ccatcaaatg tagcagttgc
    47761 gacttttact cttgcagtaa accgtacatt taagagtcaa aatggtgaac gtgaggctga
    47821 ttttatcaat gtcgttatgt ggcgccaaca ggctgaaaat cttgctaact gggctaaaaa
    47881 aggctcactt atcggggtga caggtcgtat ccagactcgt agttacgata accagcaagg
    47941 acaacgtgtc tacgtgacag aggtcgtggc tgagaatttc caaatgttgg aaagccgtag
    48001 tgtgcgtgag ggtcacacag gtggagctta ctctgcacca actgcaaact attcagcacc
    48061 tacaaattca gtaccagact tttcacgtaa tgaaaatcca tttggagcaa caaacccatt
    48121 ggatatttca gatgatgatt taccattcta atggacaact aaacttataa aggagaaaaa
    48181 acatggctca acaacgtcgt ggcggattca aacgccgtaa aaaagttgat tacatcgcag
    48241 caaacaaaat tgaatatgtt gattacaaag atactgagct tcttagccgt ttcgtttcag
    48301 aacgtgggaa aatccttcct cgtcgtgtaa caggaacttc agctaaaaac caacgtaaag
    48361 taacaacagc tatcaaacgc gctcgcgtaa tggctttgat gcctttcgta aacgaagatt
    48421 aaagaaaaga cccggttggg tctctttttc atgagcttga aaacaagaaa gcgaattaag
    48481 accccaacgg gtcttttttc acaagctttg aaatgagaga gcgagttagg ctcagtggct
    48541 tcctttttac gagtttgaaa acaagagaac acattaaaag cacgatggag ctttttcata
    48601 aatatgtctc ttttctcatc caagaaatta aaataaaaat gataaacttt ttgaaaatag
    48661 gggatttgcc tactttatga tataatggaa agagttagat tgaaagaggt agtgagatgg
    48721 acgcgaaatt aagatacaag gcaaagaaga tcaagattgt cttttttgat attgatgata
    48781 cattgcggaa ttcaaagaca gggtttattc caactacaat tcccactgtt tttaaacagt
    48841 tgcgtgaaaa aggaatttta acaggaatcg cctctggacg tggcattttt ggtgttgttc
    48901 cagagattcg tgatctcaag cctgactttt ttgtaacttt gaatggggct tatatcgaag
    48961 ataaaaaagg tcaggtcatt tatcagcatc agattgaaaa gtcagatgtt gaggagtata
    49021 tctcttgggc taagcaagaa ggaattgagt atggcttggt tgggagtcat gatgccaagt
    49081 tgtcgactcg caccgatatg atgagtgaag ctatcaatcc aatttatccc gacttagatg
    49141 tagatcccga tttccatgaa aaagaagata tctatcagat gtggactttt gaagataagg
    49201 gagatgactt gcacttgcct gacagtctct cagacaaact tcgcatggtt cgttggcatc
    49261 aacattcgtc tgatattgtg ccgatttcag gctccaaagc gacgggggtg gaaaaggttg
    49321 tggaacacct tggcttgaaa ccagagaagg tcatggtttt tggagatggt ctcaatgact
    49381 tggaactctt tgattatgct ggaatcagcg ttgccatggg aatttctcat gataaaatca
    49441 aagaaaaagc agattatatt acaaaaacat tagaagaaga tggcattttt gatgccttag
    49501 aagtatttgg tatggtagaa aaagaattgc attttccaca agtagacatt gaaacagtag
    49561 aaggtcttct tgcgactatt aagaccaatc acggagactt acgtatcaag cttttccctg
    49621 aacatgctcc taaaacagtg gctaactttg tatctctttc aaaagatggc tactatgatg
    49681 gtgtcatttt ccaccgtatt atcaaggact ttatgatcca aggtggagac ccaactggaa
    49741 ctggtatggg tggcgagtca atctacggcg aatcttttga ggatgaattc tcagaagagc
    49801 tttacaatat ccgtggtgct ctttccatgg caaatgctgg tccaaatacc aacggcagcc
    49861 agttctttat cgtgcaaaac caacacctac cttattcgaa gaaagaaatt actcgtggtg
    49921 gttggccaga accgattgca gaaatctatg ccaatcaagg tgggacacct cacctagacc
    49981 gccgtcacac ggtttttggt cagttagctg atgaagcatc ttacgctgtc ttggatgcca
    50041 ttgctgctgt tgagacagga gctatggaca agccagttga agatgttgta attgaaacta
    50101 ttgaaatcga ggactaagat gaaaatcggt gataagctaa aggggcgtat tacagggatt
    50161 cagccctacg gtgcctttgt tgagttagag acgggtgata cggggctgat tcacatttca
    50221 gaaattcgga caggatttat tgaaaatatt catgaaacct tgaaagtcga tgaagaggtt
    50281 caagttcagg tactggattt agatgaattt acggggaaag ccagtctttc tatccgcact
    50341 ttggaggaag aaaagtacca gtttcctaga cggagacgct tttcaagtga ccgctttaac
    50401 tacggttttg ctccctttcg acgaatgcta ccaatctgga ctggagaagc tctgcaccat
    50461 ttaaaaaaga agaagtagtt tagagtttta tattttttgt aatgttaata taaatttatt
    50521 ataataggac catggaagaa gaacaattat taaaatcagg agagcgcatt aaccagctct
    50581 tttcgacaga tatcaaaatc attcaaaata gagaggtttt tagctattcg gtggatagtg
    50641 ttctcttatc acgatttcca cgttttccta agaaggggtt gattgtggat ttctgtgctg
    50701 ggaatggagc agtggggctt tttgctagca ctcgtactca agcacagata ttgtctgttg
    50761 agattcagga gcgtttggcg gatatggctg aacgctctgt ccgtttgaat ggattagagg
    50821 agcaaatgca ggtcatctgc gatgatttga aaaatatgcc tgctcacatt caggggagta
    50881 aggtagatat gattttgtgt aatccaccct atttcaaggt ggatccttat tctaatctga
    50941 acgagagtga acattatctc ttggctcgac acgaaatcac gactaatttg gaagaaatct
    51001 gtcgtagtgc ccagagtatt ctcaagtcta atgggcgttt ggccatggtt catcgtcctg
    51061 atcgacttct ggatattttg gatacgttaa aacgacataa tctagcccct aagcgcctgc
    51121 agtttgttta tccaaaaaga gaaaaggaag ccaatatgct tttgattgag gcgatcaagg
    51181 atggctcaac aagtggcttt aaggtcttac ctcctttgat tgtccacaat gatgatggct
    51241 cttatacgcc cgaaatcgaa gagatttatt atggatcata aggcttatat gtacgttctg
    51301 gagtgtcgtg atggatccta ctatataggc tatacgactg atgtgagaag acgcctcgct
    51361 atccacaata gtgggaaggg agccaaatat acacgagcac gcttgccagt caaacttatc
    51421 tatgctcaag gttttgccag taaggaagaa gccatgtcgg ctgaagctct tctcaagcgt
    51481 aagaagaggc cacagaagga agaattttta tctgaaaatc aagatagaaa tttactcagt
    51541 tattttgaag aatcgtgggg agtcctttga ctcctcttac ctttgtcaaa aagcgaaaaa
    51601 aatgctacaa taaagaaaat aaacaaaatg aggtattatc atgtccaaga ttctagtatt
    51661 tggtcaccaa aatccagact cagatgccat cgggtcatct gtagcttttg cctaccttgc
    51721 aaaagaagct tacggtttgg atacggaagc tgttgccctt ggaactccaa atgaagaaac
    51781 agcctttgtc ttgaactatt ttggtgtgga agcaccacgt gttatcactt ctgccaaagc
    51841 agagggggca gagcaagtta tcttgactga ccacaatgaa ttccaacaat ctgtatcaga
    51901 tatcgctgaa gtagaagttt acggtgttgt agaccaccac cgtgtggcta actttgaaac
    51961 tgcaagccca ctttacatgc gtttggagcc agttggatca gcgtcttcaa tcgtttaccg
    52021 tatgttcaaa gaacatggtg tagctgtgcc taaagagatt gcaggtttga tgctttcagg
    52081 tttgatttca gatacccttc ttttgaaatc accaacaaca cacccaacag ataaaatcat
    52141 tgctcctgaa ttggctgaat tggctggtgt gaacttggaa gaatatggtt tggcaatgtt
    52201 gaaagctggt accaacttgg ctagcaaatc tgctgaagaa ttgattgata tcgatgctaa
    52261 gacttttgaa ctcaacggaa ataatgtccg tgttgcccaa gtgaacacag ttgacatcgc
    52321 tgaagttttg gaacgccaag cagaaattga agctgcaatg caagctgcaa acgaatcaaa
    52381 cggctactct gactttgtct tgatgattac agatatcgtc aactcaaact cagaaatctt
    52441 ggctcttggt gccaatatgg acaaggtcga agcggctttc aacttcaaac ttgaaaacaa
    52501 tcatgccttc cttgctggtg ccgtttcacg taagaaacaa gtggtacctc aattgactga
    52561 aagctttaat gcgtaagatt ttgggtgtca gctcaaaatc ggaaagtcta gtttgcctta
    52621 tatcgaaagg agtttcggct ccttttttct aggagtgaag tatgttagaa aatggcgatt
    52681 tgatttttgt gagagatggg tcagacatgg gacaggccat ccagacttcc acaggtaact
    52741 atagccatgt tgccatttat ttggatggga tgatttatca tgctagtgga caggctggtg
    52801 ttgtctgtca agaaccggca gacttctttg agtccaatca tttgtacgac ctctatgttt
    52861 acccagaaat ggatatccag tcggtgaagg aaagagcttg cagacatctt ggagcaccct
    52921 acaatgcttc tttctatcca gatgcagctg gtttctactg ctcccagtat atagcagaaa
    52981 tcctacctat ttttgaaact attcctatga aatttggaga tggggaacag gagattagtg
    53041 atttttggag ggagtattac atagaactag gtctgcctgt tcctctgaac caagctggga
    53101 ccaatcctag tcagttggca gcatcgcctc tgttacaatg taaagaaagg aatcttcatg
    53161 attcagattt ttaatccatc tcgtttgacg agacagccat ttttggagaa ttgatccgct
    53221 atctggacca gtatgaggat gtgattctac gggaaattaa ggctcaattt ccagatgttg
    53281 cagttgataa actcatggaa gagtatataa aggcaagctt gattctacgt gaaaataagc
    53341 gctattacct caattttcct acgcttgaat cacttgatag tcttgaactg gatcaagaga
    53401 tttttgtcag agaagctagt ccggtctatc aagccttgtt ggagcagagt tttgagacgg
    53461 aattgcgcaa tcaaatcaat gcagctattt tagttgaaag acggactttg cgcgcattaa
    53521 aatgaccctg tccaattatt tttacaaggt caaacagcag tatcctttga cagaaaaaca
    53581 gcaggagctc tatgacattt taggagatgt taatcctgag tatgcactca agtatatgac
    53641 ggcttttttg ttgaaatttc tcaaaaaaga ccagcttatg cagaaatgcc gtgatatctt
    53701 tgtggacagt ttggttgtct taggctatat tgtgcaaaat gaagatagaa agtatgagtt
    53761 ggctatcgat tttgataagg agagattaac tttctactta gcgtgatttc ttgtttctga
    53821 gcacattgtt tgactttcct tagtattcgg tataaactat atgtaaccgg taacacatat
    53881 cggaataaac taaaggagac aatcatatgt cacttgaaaa caaattggaa caagcaacag
    53941 gcgctgtcaa agaaggtttt ggtaaagtta ctggagacag caagacagaa cttgaaggag
    54001 ctgttgaaaa aacagttgct aaggcaaaag acgttgtaga agacgcaaaa ggtgctgtag
    54061 aaggtgccgt tgaaggtttg aaaaacgttt ttactaaata ataggaaaaa atcaagggtt
    54121 tcattttccc ttgatttttt ctattcttat aaataatttt ctgcgacggc tgtatctcct
    54181 gggtaggatt ctttcttgcc ctggatgatt tggtaacaat cggctccctt acccgcaata
    54241 ataactgcat ctaattcgtg atttgtgata gccattgccg ccttgatggc ttcttggcga
    54301 tccgcaatct tttcaacagg atgattgatg tagctactaa tttcatctgc aatggccatt
    54361 gggtcttcat agttagggtc atcagcagtc agaaagactt gaatctcagg gtgttgattg
    54421 aggaggaggc caaagtcctt acgacgactt tctcccttgt ttcctgttga tcccagaacc
    54481 agagcaatct ttccggtttg atgagtttca accacattga tgagtttttt cagactatcc
    54541 ccattgtggg catagtcgat gaagaccttg gctccatttt tctgagtgag gacttccata
    54601 cgaccaggaa cgcgggttgc agcgatgcct tttttgatgt cctcaagact tgctccgaga
    54661 cggagacaag caagtccagc agcaactgca ttttcttggt tgaagttgcc aatgagttgg
    54721 atatcataat ctccagcgag tttacccgta gctgaaaagc taaaggcttt ggaattctcg
    54781 atttggttat caaattggct accatagaaa tcatggtctt gatcttcaac ctgttctttc
    54841 aagactgaga agtggtccat gtcactgtta atgatgactg ctcggctatt ttccatcaag
    54901 agacgcttgt ggtagaaata gtcttcaaag ctagagtgtt caatcgggcc gatatggtca
    54961 ggagtgatgt taagaaagac tcctacatca aaggtcagtc catagactcg atggactaga
    55021 taggcttgac tggagacttc catgatgagg tgggtacggt cattttgcac agcctgattc
    55081 atcatgtcaa agaggtcaat actctcaggg gttgtcaacg ctgacttaaa aaaagtctcg
    55141 ccatcaagag ttgtgttcat ggtcgacaac atagcaggtc tatgcccttg agataagatg
    55201 ttataggcga aataggttgc tgttgtctta cccttagtac cagtaaaggc aaggagtttg
    55261 agtttctctt gtggattacc atagaactcc atggcaatca aactcatggc tttctttata
    55321 tcgttcacaa tgatgacagg gatatcgact tcgtagtcct tttcagctac ataccaagct
    55381 aaaccttgtg ttatagcaga aagaaggtat tcttttttaa aggcagcgcc ttttgcaaaa
    55441 aaaagagtgt cttctgttac ttttcggctg tcgtagctga tgctatcaaa aataactttg
    55501 ctgtagttgt agtggtaatg accttggtca ataatttcgc gaaaaaggcc atctttcttt
    55561 aaaatatcta atacggtttc aatcttaatc atactttcta ttgtaaaccg aaagtcgtaa
    55621 atttacaagt aacaaggaaa agtttataat ggaagataag gagtttttcc tagttatcaa
    55681 aattgaatga ggaatctatg tcgcacgaaa acaatcacca gcaggcccag atgttacggg
    55741 ggactgcttg gctaacggct agtaacttta tcagtcgcct actcggggct gtttacatta
    55801 tcccttggta catctggatg ggggcttatg cagctaaggc aaatggtctc tttaccatgg
    55861 gttacaatat ctatgcttgg ttcttgttgg tttcaacagc ggggattcca gttgcggtgg
    55921 ccaagcaagt tgccaagtat aataccatgc gagaagaaga gcatagcttt gccctgattc
    55981 ggagcttctt aggctttatg acaggactag gtctggtttt tgctttagtc ttgtatgtct
    56041 ttgctccttg gctagcagac ttgtctggcg tgggcaaaga cttgatccca atcatgcaaa
    56101 gcttggcttg gggagtcttg attttcccgt ctatgagtgt tatccgagga tttttccaag
    56161 ggatgaataa cctcaaaccc tatgctatga gccaaattgc tgagcaggtc attcgtgtta
    56221 tctggatgct cctagcaacc tttatcatta tgaagctcgg ttcaggagat tatctagcag
    56281 ccgttaccca atcaaccttt gctgcctttg tcggtatggt agccagtttt gcagtcttga
    56341 tttatttcct tgcccaagaa ggttcactca aaagagtctt tgaaacagga gataagatta
    56401 acagtaagcg tctcttggtt gataccatta aggaagccat tccttttatc ctgacagggt
    56461 ctgccatcca gctcttccag attttggatc agctgacctt tatcaatagt atgagctggt
    56521 ttaccaacta cagcaatgag gacttggttg tcatgttttc ttatttctca gccaatccta
    56581 ataaaatcac gatgattttg atttctgtag gggtttcgat tgggagtgtt ggtttgccac
    56641 ttttgacgga aaactatgtc aagggggact tgaaagcagc ttctcgtctc gttcaggaca
    56701 gtctcaccct actctttatg ttcttgctac cagcaacggt tggagtggtt atggtaggag
    56761 aacctcttta tacggtcttc tatggtaagc cagatagttt ggctctggtc ttatttgtct
    56821 ttgcagtttt gcagtctatt attttaggct tgtacatggt cttgtctcca atgcttcagg
    56881 ccatgttccg caaccgcaag gccgttctct attttatcta tggttctatt gccaagctag
    56941 tcttgcaact acctaccatc gccctcttcc acagttatgg tcctttgatt tcaacaacca
    57001 ttgctctcat cattcctaac gtcttgatgt atcgggatat ttgtaaagta actggtgtca
    57061 agcgcaaggt gattttgaag cgaaccattt taatcagttt gctgacccta gtcatgtttc
    57121 tgttaatagg aaccatccag tggctgttag gatttttctt ccaaccaagt ggacgtttgt
    57181 ggagcttctt ttatgtagct cttgtcggtg ccatgggggg tggactttat atggttatga
    57241 gtctgcgtac ctatttatta gataaggtaa taggaaaagc ccaagcagat cgcctgcgag
    57301 caaaatttaa gctttcgtaa ggtagcattt ataaataaaa ggaataagtt gaacaatctt
    57361 ttaggagaac ttgaaactta ttcctttttt agcgtcaaaa tagctaaaat tatctttcaa
    57421 aaatagaaaa tgaggttttt ttgatttttt ggaaaaaaca attgactaaa caaacccaga
    57481 gttgtataat aaaacaaata tttaaagcag gaggttctgg aaatgaaaaa gtctaagagc
    57541 aaatatctaa ccttggcagg tcttgtcctg ggtacaggag ttttattgag cgcgtgtgga
    57601 aattctagca ctgcatcaaa aacctataac tatgtttatt caagtgatcc atctagtttg
    57661 aactatctag cagaaaaccg cgcagcaaca tccgatattg ttgcaaattt ggtagacggg
    57721 ttattagaaa atgaccaata tgggaatatt attccatcat tagcagagga ttggactgtt
    57781 tctcaggacg gtttgaccta tacctacaaa cttcgtaagg atgccaagtg gtttacttct
    57841 gagggagaag aatatgcgcc tgtaactgcc caggattttg tgacaggttt gcaatatgca
    57901 gctgataaaa aatcagaagc tttgtatcta gtgcaggact ctgttgctgg tttggatgac
    57961 tatatcactg gtaaaacaag cgacttttca actgtcggtg tcaaggcact tgatgaccaa
    58021 acggttcaat atactttggt taaaccagaa ctttactgga attcaaaaac acttgcaacg
    58081 atactttttc ctgttaatgc agatttcctg aaatcaaaag gggatgattt tgggaaggcg
    58141 gatccatcta gtattttgta caatggacct ttcttgatga aagcacttgt ctcaaaatct
    58201 gctattgaat ataagaaaaa ccctaattac tgggatgcta agaatgtctt tgtagacgat
    58261 gtgaaattga cctactatga tggtagcgac caagaatcac tggaacgtaa ttttacagct
    58321 ggtgcttata ctacggctcg tctttttcct aacagctcca gctatgaagg gattaaagaa
    58381 aaatacaaaa acaatatcat atatagtatg caaaattcaa cttcatattt ctttaatttt
    58441 aacctagata ggaagtctta caattatact tctaaaacaa gtgacattga aaagaaatcg
    58501 actcaggaag cagttctcaa taaaaacttc cgtcaggcta tcaattttgc ttttgacaga
    58561 acatcttatg gggctcagtc tgaagggaaa gaaggtgcaa caaagatttt gcgtaaccta
    58621 gtggttcctc caaactttgt cagtatcaag ggaaaagact ttggtgaagt tgtagtctct
    58681 aagatggtca actatggtaa ggaatggcaa ggtatcaact ttgcggatgg tcaagaccct
    58741 tactacaatc ctgagaaagc caaggctaag tttgcggaag ctaagaaaga actcgaagca
    58801 aagggtgttc aattcccaat ccacttggat aagactgtgg aagtaacaga taaagtaggc
    58861 atacaaggag ttagttctat caaacaatca attgaatctg ttttaggttc tgataatgta
    58921 gtgattgaca ttcagcaatt aacatcagat gagtttgaca gttcaggcta ctttgctcaa
    58981 acagctgctc agaaagacta tgatttatat catggcggtt ggggacctga ttatcaagac
    59041 ccgtcaacct atctcgatat ttttaatact aatagtggag gagttctaca aaatcttgga
    59101 ctagagcctg gagaagccaa tgacaaggct aaggaagttg gactggatgt ctatactcaa
    59161 atgttggaag aagctaataa agagcaagat ccagccaaac gttatgagaa atatgctgat
    59221 attcaagctt ggttgattga tagttcttta gttcttccaa gtgtttcgcg tgggggaaca
    59281 ccatcattga gaagaaccgt accatttgct gctgcctatg gtttaaccgg tacaaaaggg
    59341 attgaatcat ataaatacct caaagtacaa gataagattg tcacaacaga cgaatatgca
    59401 aaagctagag aaaaatggtt gaaagaaaaa gaagaatcca ataaaaaagc ccaagaagaa
    59461 ttggcaaaac atgtcaaata aaatctaatt gtagataagt ttgtgtaaga agtctttgtg
    59521 cttaaaaacg cataatatca ggtatataaa atcctagatg ttatgcgttt tgttatagga
    59581 agatttatta gattttatcc tcaaattgag ttattcccga ctttatccgt tgaaatatta
    59641 taaggagtat ttatgaaatt aaaattatta agagtagata ctaaggtgat tatggggagt
    59701 ttcttacttg ttctgtctag tctacttgct ttgttgcttc cccttatctt aaagggttta
    59761 atagatggga gttctattga aaatataggt tccaaagtat ttcaatcgtt tttgattttt
    59821 attggtcaag ccttgttttc ttctattggt tactatctgt ttagtcaatc gggtgaaaaa
    59881 aagatagcaa aaatcaggaa aaaagtgata gaggggttga tttatgcaga gaaatccttc
    59941 tttgataaga gccaaagtgg ggagttgact tctgccattg tcaatgacac gagtgtcatt
    60001 cgtgagtttt taattacgac tttcccaaat attattctga gtttagttat ggtacttggt
    60061 tccattgtag tcttatttag tcttgattgg aatctttctc tacttttatt catcactctt
    60121 ccttgtatga tgtttattat cttgctcctt tccaatatca gtgaaaagta tagtcgtcgt
    60181 ttacaggagg aaatcggatt tttaacaggg taattgactg aaaagattca agaacatgaa
    60241 ttaattaaga ctaaccaagc agagaaaagt gtacaggatg ttttggataa ttgtattgaa
    60301 agggtacaaa acaattcact gaaatcagat agggttactt cttttgagac cccgtttgct
    60361 ctcttattta tctttgcgac tatagctgtg atgctaacct atgggggtta tcgggtcagc
    60421 gcaggatata tatctgtggg aaccttggtt tcgtttttga tttacctctt tcaattactt
    60481 aatcctatta gtaatatagc taattttgta actgtttatt ctaggagcaa gggatcttca
    60541 gttgcactgg agaacttgct tgcagttcct aaagaaaaat ttgagtgagg aaaatcggta
    60601 tcaggacaag ggttgaattt
//
LOCUS       DAVBOG010000007        59813 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.007, whole genome shotgun sequence.
ACCESSION   DAVBOG010000007 DAVBOG010000000
VERSION     DAVBOG010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 59813)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59813)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59813
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.007"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..856
                     /locus_tag="VQ865_000420"
                     /pseudo
     CDS             1..856
                     /locus_tag="VQ865_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            complement(973..1320)
                     /locus_tag="VQ865_000421"
     CDS             complement(973..1320)
                     /locus_tag="VQ865_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003017645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3134838.1"
                     /translation="MNLNQLDIIVSNVPQVCADLEHILDKKADYADDGFAQFTIGSHC
                     LMLSQNHLVPLENFQSGIIIHIEVEDVDQNYKRLNELGIKVLHGPTVTDWGTESLLVQ
                     GPAGLVLDFYRMK"
     gene            complement(1431..3206)
                     /gene="spxB"
                     /locus_tag="VQ865_000422"
     CDS             complement(1431..3206)
                     /gene="spxB"
                     /locus_tag="VQ865_000422"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HET3134839.1"
                     /translation="MTQGKITASAAMLNVLKTWGVDTIYGIPSGTLSSLMDALAEDKD
                     IRFLQVRHEETGALAAVMQAKFGGSIGVAVGSGGPGATHLINGVYDAAMDNTPFLAIL
                     GSRPVNELNMDAFQELNQNPMYNGIAVYNKRVAYAEQLPKVIDEACRAAVSKKGPAVV
                     EIPVNFGFQEIDENSYYGSGSYERSFIAPALNEVEIDKAVEILNNAERPVIYAGFGGV
                     KAGEVITELSRKIKAPIITTGKNFEAFEWNYEGLTGSAYRVGWKPANEVVFEADTVLF
                     LGSNFPFAEVYEAFKNTEKFIQVDIDPYKLGKRHALDASILGDAGQAAKAILDKVNPV
                     ESTPWWRANVKNNQNWRDYMNKLEGKTEGELQLYQVYNAINKHADQDAIYSIDVGNTT
                     QTSTRHLHMTPKNMWRTSPLFATMGIALPGGIAAKKDNPDRQVWNIMGDGAFNMCYPD
                     VITNVQYDLPVINLVFSNAEYGFIKNKYEDTNKHLFGVDFTNADYAKIAEAQGAVGFT
                     VDRIEDIDAVVAEAVKLNKEGKTVVIDARITQHRPLPVEVLELDPKLHSEEAIKAFKE
                     KYEAEELVPFRLFLEEEGLQSRAIK"
     gene            complement(3413..5656)
                     /locus_tag="VQ865_000423"
     CDS             complement(3413..5656)
                     /locus_tag="VQ865_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3134840.1"
                     /translation="MTEIVKASLENGIQKIRIRAEKGYHPAHIQLQKGIPAEITFHRA
                     TPSNCYKEILFEEEGILEPIGVDEEKVIRFTPQELGRHEFSCGMKMQKGSYIVVEKTR
                     KSLSLLQRFWITSIFTVPLVILMIGMLTGSISHQVMHWGTFLATTPIMLVAGKPYIQS
                     AWASFKKHNANMDTLVALGTLVAYFYSLVALFAGLPVYFESAGFILFFVLLGAVFEEK
                     MRKNTSQAVEKLLDLQAKTAEVLSDDSYVQVPLEQVKVGDLIRVRPGEKIAVDGVVVE
                     GVSSIDESMVTGESLPVDKTVGDTVIGSTINHSGTLVFRAEKVGSETVLAQIVDFVKK
                     AQTSRAPIQDLTDKISGIFVPVVVILGIMTFWVWFVLLRDSVVVLGASFVSSLLYGVA
                     VLIIACPCALGLATPTALMVGTGRSAKMGVLLKNGTVLQEIQKVQTLVFDKTGTLTEG
                     KPVVTDIIGDEVEVFGLAASLEDASQHPLAEAIVKRASEAGLEFQTVENFQALHGKGV
                     SGRINGKQVLLGNAKMLDGMDISNTYQDKLEELEKEAKTVVFLAVDNEIKGLLALQDI
                     PKENAKLVISQLKKRGLRTVMLTGDNAGVARAIADQIGIEEVIAGVLPEEKAHEIHKL
                     QQSGKVAFVGDGINDAPALSVADVGIAMGAGTDIAIESADLVLTTNNLLGVVRAFDMS
                     KKTFHRILLNLFWAFIYNVVGIPIAAGVFSGVGLALNPELAGLAMAFSSVSVLTSSLL
                     LNFSKID"
     gene            complement(5666..6037)
                     /locus_tag="VQ865_000424"
     CDS             complement(5666..6037)
                     /locus_tag="VQ865_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupredoxin domain-containing protein"
                     /protein_id="HET3134841.1"
                     /translation="MLNSIVTIICIALIAFILFWFFKKPEKSGQKAQQKNGYQEIRVE
                     VMGGYTPELIVLKKSVPARIVFDRKDPSPCLDQIVFPDFGVHANLPMGEEYVVEITPE
                     QVGEFGFACGMNMMHGKMIVE"
     gene            complement(6048..6443)
                     /locus_tag="VQ865_000425"
     CDS             complement(6048..6443)
                     /locus_tag="VQ865_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HET3134842.1"
                     /translation="MQISDAEWQVMKIIWMQGEQTSTDLIRVLAERFDWSKSTIQTLL
                     ARLVEKECLTRKKEGKSFVYSALLTLDQSRDLLVQDIKDKVCSRRIRNLLADLIVECE
                     FTQTDLEDLEAVISEKKSSAVTEVRCNCM"
     regulatory      6627..6725
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            6809..7600
                     /gene="thiD"
                     /locus_tag="VQ865_000426"
     CDS             6809..7600
                     /gene="thiD"
                     /locus_tag="VQ865_000426"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3134843.1"
                     /translation="MTYLPVALTIAGTDPSGGAGIMADLKSFQARDVYGMAVVTSLVA
                     QNTRGVQLIEHVSPQMLKAQLESVFSDIPPQAVKTGMLATTEIMEIIQPYLKKLDCPY
                     VLDPVMVATSGDALIDSSARDYLKTNLLPLATIITPNLPEAEEIVGFSIHDPEGMQRA
                     GRLILKEFGPQSVVIKGGHLKGGAKDFLFTKNEQFVWESPRIQTCHTHGTGCTFAAVI
                     TAELAKGKSLYQAVDKAKAFITKAIQDAPQLGHGSGPVNHTTFKD"
     gene            complement(7809..8441)
                     /locus_tag="VQ865_000427"
     CDS             complement(7809..8441)
                     /locus_tag="VQ865_000427"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3134844.1"
                     /translation="MNREALRLYLVTNRYQDSVESFLAKVETACRSGVTIVQLREKNL
                     TTNQYYQLAKQVKEITDAYQVPLIIDDRLDVCLAVDAAGLHIGDDELPVSVARKVLGP
                     EKILGVTAKTVKRALEAEKSGADYLGTGAIFPTTTKENAPITLISTLKTICQTVAIPV
                     VAIGGLTSENIDQLMGTGIAGVAVVRDLMQAEDIEAKTQAFLTKLHDILS"
     gene            complement(8434..9237)
                     /locus_tag="VQ865_000428"
     CDS             complement(8434..9237)
                     /locus_tag="VQ865_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3134845.1"
                     /translation="MQALTNPFPIGSSSLIHCMTNEISCEMLANGILALGCKPVMADD
                     PREVLDFTKQSQALFINLGHLSAEKEKAIRMAASYANQSSLPMVVDAVGVTTSSIRKS
                     LVKDLLDYRPTVLKGNMSEIRSLVGLKHHGVGVDASAKDQETEDLLQVLKDWCQTYPG
                     MSFLVTGPKDLIVSENQVAVLENGCTELDWITGTGDLVGALTAVFLSQGKTGFEASCL
                     AVSYLNIAAEKIVVQGMGLEEFRYQVLNQLSLLRRDENWLDTIKGEVYE"
     gene            complement(9237..9761)
                     /gene="thiW"
                     /locus_tag="VQ865_000429"
     CDS             complement(9237..9761)
                     /gene="thiW"
                     /locus_tag="VQ865_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001225563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy coupling factor transporter S component
                     ThiW"
                     /protein_id="HET3134846.1"
                     /translation="MRKHQLQVHKLTILSMMIALDVVLTPIFRIEGMAPMSSVVNILA
                     GIMMGPVYALAMATVTAFIRMTTQGIPPLALTGATFGALLAGLFYKYGRKFYFSALGE
                     IVGTGIIGSIVSYPVMVLFTGSAAKLSWFIYTPRFFGATLIGTAISFIAFRFLIKQEF
                     FKKVQGYFFAERIE"
     gene            complement(9766..10458)
                     /gene="tenA"
                     /locus_tag="VQ865_000430"
     CDS             complement(9766..10458)
                     /gene="tenA"
                     /locus_tag="VQ865_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiaminase II"
                     /protein_id="HET3134847.1"
                     /translation="MEFTDIAMELSKKAWQASFHHPFILQLQEGNLEPAIFRYYLIQD
                     AYYLKAFSEIYHLLADKTSNQEMKRLLKQNAQGLVEGELFIRQQFFKELEINDQEMEQ
                     HPIAPTCYHYISHIYRQFAEPNLAIAFASLLPCPWLYHDIGKSLNLKPSPNPLYQQWI
                     ETYITDELEQQIREEGALVNQLYRESDETDKQKMLDAFHISVHMEAKFWEMAYQHQTW
                     KSDLQSLEKGEE"
     gene            complement(10469..11119)
                     /locus_tag="VQ865_000431"
     CDS             complement(10469..11119)
                     /locus_tag="VQ865_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cobalt ABC transporter permease"
                     /protein_id="HET3134848.1"
                     /translation="MVKVATQTPIISLFLLILSLETSFIPSIALNLSVVAFCILFMLY
                     YRRFKMLAWMIILAILPSFANYWAVQLHGDASQAVMLGTRAFVTVCIGLVFVSSISLK
                     ELLLYLAQKGLSRSWSYALIVVFNSFPLIQQEIKSLKEACLLRGQKLHFWSPLIYSKV
                     LMTVFRWRHLYLRALSAHGYDEHAQLKNSYRTFYIPKKTKLIYLLFFLLLQTSLFL"
     gene            complement(11121..12506)
                     /locus_tag="VQ865_000432"
     CDS             complement(11121..12506)
                     /locus_tag="VQ865_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000522086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134849.1"
                     /translation="MGLELRAIQSPIFSEPFDFTFHAQAFTLLVGSSGSGKSSLFQMI
                     AQVSSLPYSGQVLIDGSEVSQLSIIARVQKVGILLQNPNHQFTMENLFEELIFTLENI
                     GYHLQEIDSKIAEVVQQCRCEAILHRPIHHLSGGEKQKAALAVLFAMNPRVYLLDEPF
                     ASIDRKSRIEILEILKELALDGKTVILCDHDLSDYKAYIDHMVELRDGKLREINQIPS
                     YEMTQVASKEVASSPELFHMNRVTGELGNRPLFSIADFTFYQGISCILGDNGVGKSTL
                     FRSILQFQKYKGRIAWKGTVLKKKKSLYRDLTGVVQEAEKQFIRVSLREELQLDGPDS
                     ERNQRIFQALRYFDLEQAVDKSPYQLSGGQQKILQLLTILTSKASVILLDEPFAGLDD
                     RACHYFCKWIVEERNQGRSFLLISHRLDPLISVVDYWIEMTSQGLRHVKEVTITKPLT
                     SQSSNTQGEVR"
     gene            complement(12507..13067)
                     /locus_tag="VQ865_000433"
     CDS             complement(12507..13067)
                     /locus_tag="VQ865_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000915269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3134850.1"
                     /translation="MLKKWQLKDVILLAFLSIFFGGVFVGSGYVYNILSLLLTPLGLQ
                     AFANEILFGLWCMAAPIAAIFVPRVGSATIGEVLAALAEVLYGSQFGLGALLSGLVQG
                     LGSEFGFIVTKNRYESWLSLTANSIGITLVSFVYEYIKLGYYAFSLPFVLSLLVVRFI
                     SVYFFCTILVRAIVKLYHQFATGGKA"
     regulatory      complement(13329..13417)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(13626..14255)
                     /locus_tag="VQ865_000434"
     CDS             complement(13626..14255)
                     /locus_tag="VQ865_000434"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000468574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HET3134851.1"
                     /translation="MFHKELLKLYFICGTTTCQGKNLYTVVEEALKGGITLFQFREKG
                     EGALEGLEKLELAIQIKELCKKYNVPFIVNDDIDLAMEIDADGVHVGQDDIGVDEIRK
                     LMPDKIIGLSIKNEEEFQQSKVEYVDYVGVGPVFDTQSKDDAGGAIGYEGLELMRKLL
                     PQMPLVAIGGIQTKHIKDIIKTNVDGVSIISAISYAKNIEKTVREMSEQ"
     gene            complement(14257..15039)
                     /gene="thiM"
                     /locus_tag="VQ865_000435"
     CDS             complement(14257..15039)
                     /gene="thiM"
                     /locus_tag="VQ865_000435"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HET3134852.1"
                     /translation="MTSLKLLKEKAPLVICITNDVVKNFTANGLVALGASPAMSEFPA
                     DLEDLLKYAGGLLINIGTLTDENWKLYQAALKIAEKYNVPAVLDPVACGAGEYRKKVA
                     DDLINNYKLAAIRGNAGEIASLVGIDVASKGVDSAGVDNIDEIALAANEKFNIPIVVT
                     GEVDAIAVNGEVVTIHNGSAMMPKVIGTGCLLGAVVASFIGLEKGQELKSLETAMLVY
                     NIAGEMAEKRPNGHLPGTFKVEFINALYEITDEDVKKFKRVK"
     gene            complement(15450..15989)
                     /locus_tag="VQ865_000436"
     CDS             complement(15450..15989)
                     /locus_tag="VQ865_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000449826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TenA family protein"
                     /protein_id="HET3134853.1"
                     /translation="METQDYAFQPGLTVGELLKSSQKDWQAAINHRFVKELFAGTIEN
                     KVLKDYLIQDYHFFDAFLSMLGACVAHADKLESKLRFAKQLGFLEADEDGYFQKAFKE
                     LKVAENNYLEVTLHPVTKAFQDLMYWAVASSDYAHLLVMLVIAEGLYLDWGSKDLALP
                     EVYIHSEWINLHRGPFFAE"
     regulatory      complement(16204..16292)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(16546..17682)
                     /gene="lctO"
                     /locus_tag="VQ865_000437"
     CDS             complement(16546..17682)
                     /gene="lctO"
                     /locus_tag="VQ865_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate oxidase"
                     /protein_id="HET3134854.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TLRENIRAFNHKLIVPHTLCDVENPSTEIEFAGEKLSSPIIMAPVAAHKLANEQGEVA
                     TARGVHEFGSLYTTSSYSTVDLPEISEALQGTPHWFQFYFSKDDGINRHIMDRVKAEG
                     YKAIVLTADATVGGNREVDKRNGFVFPVGMPIVEEYLPEGAGKSMDFVYKSAKQRLSP
                     RDVEFIAEYSGLPVYVKGPQCREDVERSLAAGASGIWVTNHGGRQIDGGPAAFDSLQE
                     VAEAVDRRVPIVFDSGVRRGQHVFKALASGADLVAIGRPVIYGLALGGSVGVRQVFEH
                     LNAELKTVMQLSGAQTIEDVKHFKLRHNPYNPTFPVDPRDLKLY"
     gene            complement(18308..19798)
                     /gene="lysS"
                     /locus_tag="VQ865_000438"
     CDS             complement(18308..19798)
                     /gene="lysS"
                     /locus_tag="VQ865_000438"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003055423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HET3134855.1"
                     /translation="MSTEHMEELNDQQIVRREKMAALREQGIDPFGKRFERTANSQEL
                     KDKYANLDKEQLHDKNETATIAGRLVTKRGKGKVGFAHLQDREGQIQIYVRKDAVGEE
                     NYEIFKKADLGDFLGVEGEVMRTDMGELSIKATHITHLSKALRPLPEKFHGLTDVETI
                     YRKRYLDLISNRESFERFVTRSKIISEIRRYLDQKGFLEVETPVLHNEAGGAAARPFI
                     THHNAQNIDMVLRIATELHLKRLIVGGMERVYEIGRIFRNEGMDATHNPEFTSIEVYQ
                     AYADFQDIMDLTEGIIQHAAKSVKGDGPVNYQGTEIKINEPFKRVHMVDAIREITGVD
                     FWQDMTLKEAKAIAAEKKVPVEKHYTEVGHIINAFFEEFVEETLIQPTFVYGHPVAVS
                     PLAKKNPEDQRFTDRFELFIMTKEYGNAFTELNDPIDQLSRFEAQAKAKELGDDEATG
                     IDYDYIEALEYGMPPTGGLGIGIDRLCMLLTDTTTIRDVLLFPTMK"
     gene            complement(19926..20072)
                     /locus_tag="VQ865_000439"
     CDS             complement(19926..20072)
                     /locus_tag="VQ865_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate oxidase"
                     /protein_id="HET3134856.1"
                     /translation="MSYKTSNAEGHVDFINTYDLEPMAQQVIPKAAFGYIASGAEDTF
                     TSFQ"
     gene            20299..20967
                     /locus_tag="VQ865_000440"
     CDS             20299..20967
                     /locus_tag="VQ865_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006531263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3134857.1"
                     /translation="MVEQYLPLYQKAFFLTLHIAVWGILGSFLLGLIVSIIRHYRIPV
                     LAQVATAYIELSRNTPLLIQLFFLYFGLPLIGIVLSSEVCATLGLVFLGGSYMAESFR
                     SGLEAISQTQQEIGLAIGLTPLQVFRYVVLPQATAVVLPSFSANVIFLIKKTSVFSAV
                     ALADLMYVAKDLIGLYYETDIALAMLVVAYLIMLLPISLVFSWIERRTFHAGFGNPST
                     LSRK"
     gene            20927..21307
                     /locus_tag="VQ865_000441"
     CDS             20927..21307
                     /locus_tag="VQ865_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154138.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HET3134858.1"
                     /translation="MQDSGIQVLFQGNNLLRILQGLGVTIGISILSVLLSMMFGTVMG
                     IIMTSHSRIIRFLTRLYLEFIRIMPQLVLLFIVYFGLARNFNINISGETSAIIIFTLW
                     GTAEMGDLVRGAITSLPKHQFESG"
     gene            21317..21604
                     /locus_tag="VQ865_000442"
     CDS             21317..21604
                     /locus_tag="VQ865_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3134859.1"
                     /translation="MTNVQLYYHIIIPQVLRRLLPQAINLVTRMIKTTSLVVLIGVVE
                     VTKVGQQIIDSNRLTIPTASFWIYGTILVLYFAVCYPISKLSTHLEKHWRN"
     gene            21605..22373
                     /locus_tag="VQ865_000443"
                     /pseudo
     CDS             21605..22373
                     /locus_tag="VQ865_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000401.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
     gene            22385..23251
                     /locus_tag="VQ865_000444"
     CDS             22385..23251
                     /locus_tag="VQ865_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3134860.1"
                     /translation="MKLFKPLLTVLALAFALIFITACSSGGNAGSSSGKTTAKARTID
                     EIKKSGELRIAVFGDKKPFGYVDNDGSYQGYDIELGNQLAQDLGVKVKYISVDAANRA
                     EYLISNKVDITLANFTVTDERKKQVDFALPYMKVSLGVVSPKTGLITDVKQLEGKTLI
                     VTKGTTAETYFEKNHPEIKLQKYDQYSDSYQALLDGRGDAFSTDNTEVLAWALENKGF
                     EVGITSLGDPDTIAAAVQKGNQELLDFINKDIEKLGKENFFHKAYEKTLHLTYGDAAK
                     ADDLVVEGGKVD"
     gene            complement(23338..23985)
                     /locus_tag="VQ865_000445"
     CDS             complement(23338..23985)
                     /locus_tag="VQ865_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134861.1"
                     /translation="MNEIITLKNIQLELKKTCVFQNLNFSCKQGEIIGITGANGSGKS
                     VLFKLIAGLYSPSYGEVLINGENIVPERKIPANLGALIEEPGFINYYSGFKNLQYLAS
                     IRGVVGNQEINDTLKIVGLYEQKDQKVKTYSLGMRKKLGIAQAIMENPSILLLDEPMN
                     ALDKSSVENMRTLFRKLSSEKGTTILIASHSEEDIRILCDKVYAIEDKVCTLCSD"
     gene            complement(23982..24680)
                     /locus_tag="VQ865_000446"
     CDS             complement(23982..24680)
                     /locus_tag="VQ865_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134862.1"
                     /translation="MGKLSSHMWRLNQIIYTKYFWGYVLFWILICLGLWYWLEGNDRL
                     VIEILKGPNLSQNSFLVLSIWLLHWFIIHTFFLAVVYRRRASDFFMEVIRFSSIKLWI
                     RYQIWTCFLYGLILIMVKVLVIQFMLQLPNWDIGVLFIVDSLNACVLVLFCFMLYVLG
                     ANEQMNFSCVSFFLLMIVFGGLFVGNRTNYLFYILNRGNGDIGRDLFLQLLFLVFLFK
                     SIFYFTRQKRRFIE"
     gene            complement(24690..25442)
                     /locus_tag="VQ865_000447"
     CDS             complement(24690..25442)
                     /locus_tag="VQ865_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134863.1"
                     /translation="MKQFVQFYKKDFLAVLVYFILLLSCVLSSTVYLLRCRQYSIHPN
                     VLEWILVLLQDMTTGVYCFPFTYILFFFYLMNNYFNRLECRIRLKSIKHFTSFSFKLA
                     ALSTGIWTATLFLLIFLIAFSNGFSFSLEIKEVDFLREFYGISIANNASFFIGFFFSY
                     IAYYFFLSLLTISSFSWFKKSNMSLVFLFTFLFVESLFWIYQLDNGIIGLLPIFQYMV
                     NSNPYALIYWLTLLSIIIPLTVFSVHRNWRRV"
     gene            complement(25442..26206)
                     /locus_tag="VQ865_000448"
     CDS             complement(25442..26206)
                     /locus_tag="VQ865_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134864.1"
                     /translation="MEFFICNLVRVVQSPRFYMSLFLTLLCMSLGNFLAFNGIYKIEG
                     LSIFFAASSIRGFSPISLVAALICTLPYSSQIIEDAESHFLTAQLCRISKKRYLAIVG
                     STAIISSFLVFFLPYLLLLGINLLVTPYQEIYIGDYSGALKELFDSNQFLYSLVTTLW
                     YGVWGAVFSIFGLASALLVKKKLGAIFIPVAYMMVGGILWAILGLSYLEPVTTLALGY
                     QKDISLSLVSGHLAFILFVSCLVVYGTFFLHSEDYV"
     gene            complement(26302..26705)
                     /locus_tag="VQ865_000449"
                     /pseudo
     CDS             complement(26302..26705)
                     /locus_tag="VQ865_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829085.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(26885..27517)
                     /locus_tag="VQ865_000450"
     CDS             complement(26885..27517)
                     /locus_tag="VQ865_000450"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HET3134865.1"
                     /translation="MTLAKDIASHLLKIQAVYLKPEEPFTWASGIKSPIYTDNRVTLA
                     YPETRTLIENGFVEAIKEAFPEVEVIAGTATAGIPHGAIIADKMDLPFAYIRSKPKDH
                     GAGNQIEGRVAQGQKMVVVEDLISTGGSVLEAVAAAKREGADVLGVVAIFSYQLPKAD
                     KNFADAGVKLVTLSNYSELIHLAQEEGYITPEGLDLLKRFKEDQENWQEG"
     gene            complement(27551..28252)
                     /gene="pyrF"
                     /locus_tag="VQ865_000451"
     CDS             complement(27551..28252)
                     /gene="pyrF"
                     /locus_tag="VQ865_000451"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001206708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HET3134866.1"
                     /translation="MREHRPIIALDFPSFEAVKEFLALFPAEESLYLKVGMELYYAAG
                     PEIVSYLKGLGHSVFLDLKLHDIPNTVKSAMKVLSQLGVDMTNVHAAGGVEMMKAARE
                     GLGSQAKLIAVTQLTSTSEAQMQEFQNIQTSLQESVIHYAKKTAEAGLDGVVCSAQEV
                     QVIKQATNPDFICLTPGIRPAGVAVGDQKRVMTPADAYQIGSDYIVVGRPITQAEDPV
                     AAYHAIKDEWTQDWN"
     gene            complement(28485..29684)
                     /gene="divIB"
                     /locus_tag="VQ865_000452"
     CDS             complement(28485..29684)
                     /gene="divIB"
                     /locus_tag="VQ865_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DivIB"
                     /protein_id="HET3134867.1"
                     /translation="MSKDKKNEDKEILEELKELSEWQKRNQEYLKKKAEEEAALAEEK
                     EKERQARMGEESEKSEDKQDQESETDQEDSESAKEESEEKVASSEADKEKEEKEEPES
                     KEKEEQDKKLSKKATKEKPAKAKIPGIHILRAFTILFPSLLLLIVSAYLLSPYATMKD
                     IRVEGTVQTTADDIRQASGIQDSDYTINLLLDKAKYEKQIKSNYWVESAQLVYQFPTK
                     FTIKVKEYDIVAYYISGENHYPILSSGQLETSSVSLNSLPETYLSVLFNDSEQIKVFV
                     SELAQISPELKAAIQKVELAPSKVTSDLIRLTMNDSDEVLVPLSEMSKKLPYYSKIKP
                     QLSEPSVVDMEAGIYSYTVADKLIMEAEEKAKQEAKEAEKKQEEEQKKQEEESNRNQT
                     TQRSSRR"
     gene            complement(29694..30752)
                     /locus_tag="VQ865_000453"
     CDS             complement(29694..30752)
                     /locus_tag="VQ865_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--N-acetylmuramyl-
                     (pentapeptide) pyrophosphoryl-undecaprenol
                     N-acetylglucosamine transferase"
                     /protein_id="HET3134868.1"
                     /translation="MKKIVFTGGGTVGHVTLNLLLMPKFIEDGWEVHYIGDKRGIEHQ
                     EILKSGLDVTFHSIATGKLRRYFSWQNMLDVFKVCWGIVQSLFIMLRLRPQTLFSKGG
                     FVSVPPVIAARVSGVPVFIHESDLSMGLANKIAYKFATKMYSTFEQASSLSKVEHVGA
                     VTKVSDQKNPEPDELVDIQSHFNHKLPTVLFVGGSAGARVFNQLVTDHKKELTERYNI
                     INLTGDSSLNELSQNLFRVDYVTDLYQPLMELADIVVTRGGANTIFELLAIAKLHVIV
                     PLGREASRGDQLENAAYFVKKGYAEDLQESDLTLDSLEEKLSHLLSHKEDYQAKMKAS
                     KELKSLADFYQLLKKDLS"
     gene            complement(30754..32106)
                     /locus_tag="VQ865_000454"
     CDS             complement(30754..32106)
                     /locus_tag="VQ865_000454"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HET3134869.1"
                     /translation="MKVIDQFKNKKVLVLGLAKSGESAARLLDKLGAIVTVNDGKPFE
                     DNPAAQSLLEEGIKVITGGHPLELLDEEFALMVKNPGIPYNNPMIEKALAKGIPVLTE
                     VELAYLISEAPIIGITGSNGKTTTTTMIGEVLTAAGQHGLLSGNIGYPASQVAQIASD
                     KDTLVMELSSFQLMGVQEFHPEIAVITNLMPTHIDYHGSFSEYVAAKWNIQNKMTAAD
                     FLVLNFNQDLAKDLTSKTEATVVPFSTLEKVDGAYLEDGQLYFRGEVVMAANEIGVPG
                     SHNVENALATIAVAKLRGVDNQTIKETLSAFGGVKHRLQFVDDIKGVKFYNDSKSTNI
                     LATQKALSGFDNSKVVLIAGGLDRGNEFDELVPDITGLKKMVILGQSAERVKRAADKA
                     GVAYVEATDIADATRKAYELATQGDVVLLSPANASWDMYANFEVRGDLFIDTVAELKE
                     "
     gene            complement(32210..32851)
                     /locus_tag="VQ865_000455"
     CDS             complement(32210..32851)
                     /locus_tag="VQ865_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134870.1"
                     /translation="MIELKNISKKFGSRQLFSDTNLHFEGGKIYALIGTSGCGKTTFL
                     NMIGRLEPYDKGQIIYDGTSLKDIKPSVFFRDYLGYLFQDFGLIESQTVKENLNLGLV
                     GKKLKEKEKISLMKQALNCVNLSYLDLKQPIFELSGGEAQRVALAKIILKDPPLILAD
                     EPTTSLDPKNSEELLSILESLKNPNRTIIIATHNPLIWEQVDQVIRVTDLSHR"
     gene            complement(32853..34873)
                     /locus_tag="VQ865_000456"
                     /pseudo
     CDS             complement(32853..34873)
                     /locus_tag="VQ865_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000732428.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(34944..35243)
                     /locus_tag="VQ865_000457"
     CDS             complement(34944..35243)
                     /locus_tag="VQ865_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3134871.1"
                     /translation="MKTKKHRLLALALISSFTLLGAASAAVQYPDGGVWTYGEGSGGG
                     WAFSNYYHGKKYHYSSLVSRWNSHSDKGEASAGKTSYAWIWTKWGEQVAFYCDYD"
     gene            complement(35609..35863)
                     /locus_tag="VQ865_000458"
     CDS             complement(35609..35863)
                     /locus_tag="VQ865_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3165 family protein"
                     /protein_id="HET3134872.1"
                     /translation="MVYLVLGILLLLLYVFATPESIKGTVNIVAMVCILVALLILLVL
                     SFLKIFQLPTEIFLAIAMLILAYFSVRDITLMPVKKSKRR"
     gene            complement(35883..37724)
                     /gene="typA"
                     /locus_tag="VQ865_000459"
     CDS             complement(35883..37724)
                     /gene="typA"
                     /locus_tag="VQ865_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003078415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HET3134873.1"
                     /translation="MTKLREDIRNIAIIAHVDHGKTTLVDELLKQSETLDARTELAER
                     AMDSNDIEKERGITILAKNTAVAYNGTRINIMDTPGHADFGGEVERIMKMVDGVVLVV
                     DAYEGTMPQTRFVLKKALEQDLVPIVVVNKIDKPSARPAEVVDEVLELFIELGADDDQ
                     LDFPVVYASAINGTSSLSDDPADQEATMAPIFDTIIDHIPAPVDNSDEPLQFQVSLLD
                     YNDFVGRIGIGRVFRGTVKVGDQVTLSKLDGTTKNFRVTKLFGFFGLERREIQEAKAG
                     DLIAVSGMEDIFVGETITPTDAVEALPILHIDEPTLQMTFLVNNSPFAGKEGKWVTSR
                     KVEERLQAELQTDVSLRVDPTDSPDKWTVSGRGELHLSILIETMRREGYELQVSRPEV
                     IVKEIDGVKCEPFERVQIDTPEEYQGSVIQSLSERKGEMLDMISTGNGQTRLVFLVPA
                     RGLIGYSTEFLSMTRGYGIMNHTFDQYLPLIPGEIGGRHRGALVSIDAGKATTYSIMS
                     IEERGTIFVNPGTEVYEGMIIGENSRENDLTVNITKAKQMTNVRSATKDQTAVIKTPR
                     ILTLEESLEFLNDDEYMEVTPESIRLRKQILNKAEREKANKKKKSAE"
     gene            37886..38611
                     /locus_tag="VQ865_000460"
     CDS             37886..38611
                     /locus_tag="VQ865_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3134874.1"
                     /translation="MRLDNLLAQEKVSRKAMKQALLRGEILVDGCPARSLAQNIDTGL
                     QELLFQDRIIQGYEHTYLMLHKPAGVVTANKDKELPTVMDLLPSDIQSDKLYAVGRLD
                     RDTTGLLLLTDNGPLGFQLLHPQYHVDKTYQVEVNGLLTPDHIQTFQKGIVFLDGTIC
                     KPARLEILSASPSLSQASITISEGKFHQIKKMFLSVGVKVTNLKRIQFGDFTLNPDLA
                     EGNYHPLNQKELQIIKNYLEMSR"
     gene            complement(38651..38878)
                     /locus_tag="VQ865_000461"
     CDS             complement(38651..38878)
                     /locus_tag="VQ865_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134875.1"
                     /translation="MKEKKKNPLFVGILSIILGLLFPIVGLILGIIGLVLAISYQKES
                     QLDYKIEKILNILGIVISVVNWIVAIALIFR"
     gene            complement(38967..39347)
                     /locus_tag="VQ865_000462"
     CDS             complement(38967..39347)
                     /locus_tag="VQ865_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3134876.1"
                     /translation="MVTWILWALILAMLAWMGFNYLRIRRAAKIVDNEEFEALIRTGQ
                     LIDLRDPAEFHRKHILGARNIPSSQLKTSLAALRKDKPVLLYENQRAQRVTNAALYLK
                     KQGFSEIYILSYGLDSWKGKVKTS"
     gene            complement(39347..39616)
                     /locus_tag="VQ865_000463"
     CDS             complement(39347..39616)
                     /locus_tag="VQ865_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HET3134877.1"
                     /translation="MSLFLKKTQNFARMSLMKTFYDVQQFLKRFGIIVYMGKRLYDIE
                     LMKLELSRIYDAGLMDKLDYLEAEAVLRREHKVELDYIEKNGEKN"
     gene            39680..40588
                     /locus_tag="VQ865_000464"
     CDS             39680..40588
                     /locus_tag="VQ865_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3134878.1"
                     /translation="MRIQQLHYIIKIVETGSMNEAAKQLFITQPSLSNAVRDLENEMG
                     IEIFIRNPKGITLTRDGMEFLSYARQVVEQTQLLEERYKNPVAHRELFSVSSQHYAFV
                     VNAFVSLLKKSDMEKYELFLRETRTWEIIDDVKNFRSEVGVLFLNSYNRDVLTKMLDD
                     NHLLAHHLFTAQPHIFVSKTNPLAKKDKVKLSDLENFPYLSYDQGTHNSFYFSEEILS
                     QEHHKKSIVVSDRATLFNLLIGLDGYTIATGILNSNLNGDNIVSIPLDIDDPIELVYI
                     QHEKTSLSKMGERFIDYLLEEVQFDS"
     gene            complement(40642..41397)
                     /locus_tag="VQ865_000465"
     CDS             complement(40642..41397)
                     /locus_tag="VQ865_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001142149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HET3134879.1"
                     /translation="MPTILITGASGGLAQEMVKLLPNDQLILLGRNKEKLAQLYGNYS
                     HAELIEIDITDDSALEALVTDLYLRYGKIDVLINNAGYGIFEGFDQIADKDIHQMFEV
                     NTFALMNLSRHLAARMKESSKGHIINIVSMAGLIATGKSSLYSATKFAAIGFSNALRL
                     ELMPYGVYVTTVNPGPIRTGFFDQADPDGTYLKSVDRFLLEADAVAKKIVKIIGKNKR
                     ELNLPILLNLAHKFYTLFPKLADKLAGETFNYK"
     gene            complement(41418..42347)
                     /locus_tag="VQ865_000466"
     CDS             complement(41418..42347)
                     /locus_tag="VQ865_000466"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HET3134880.1"
                     /translation="MDIQFLGTGAGQPSKARNVSSLALKLLDEINEVWLFDCGEGTQN
                     RILETTIRPRKVSKIFITHLHGDHIFGLPGFLSSRAFQANEEQTDLEIYGPQGIKSFV
                     LTSLRVSGSRLPYRIHFHEFDQDSLGKILETDKFTVYAEELDHTIFCVGYRVMQKDLE
                     GTLDAEKLKAAGVPFGPLFGKIKNGQDLVLEDGTEIKAADYISAPRPGKIITILGDTR
                     KTDASVRLAVNADVLVHESTYGKGDEKIARNHGHSTNMQAAQVAVEAGAKRLLLNHIS
                     ARFLSKDISKLKKDAATIFENVHVVKDLEEVEI"
     gene            complement(42362..42985)
                     /locus_tag="VQ865_000467"
     CDS             complement(42362..42985)
                     /locus_tag="VQ865_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HET3134881.1"
                     /translation="MTDIKTLALKYGGYTSLDKVYLDQLLAGKTEQEQLTLITPPPSV
                     VNAYFAELYQKKSPQAATDYFAELSQELNLYNTEPSFTLENKPFIRLNLSGKSFGFCY
                     ESDGLGRIFSENEEKISDDLLFEIAQIFSHQLVFEESGKIYMKPVKDEEVVSLESLTA
                     LTDLERLADGRKRLKGYSQEDLLQEAAAFSGKRYFRSENRTAMLYID"
     gene            complement(42978..44216)
                     /gene="hflX"
                     /locus_tag="VQ865_000468"
     CDS             complement(42978..44216)
                     /gene="hflX"
                     /locus_tag="VQ865_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HET3134882.1"
                     /translation="MIETEKKEERVLLIGVELQGMDSFDLSMEELASLAKTAGAVVVD
                     SYRQKREKYDSKTFVGSGKLEEIALMVDAEEITTVIVNNRLTPRQNVNLEEVLGVKVI
                     DRMQLILDIFAMRARSHEGKLQVHLAQLKYLLPRLVGQGIMLSRQAGGIGSRGPGESQ
                     LELNRRSVRNQITDIERQLKVVEKNRATVREKRLESSTFKIGLIGYTNAGKSTIMNIL
                     TSKTQYEADELFATLDATTKSIHLGGNLQVTLTDTVGFIQDLPTELVSSFKSTLEESK
                     HVDLLVHVIDASNPYHEEHEKTVLSIMKDLDMEDIPHLTLYNKADLVEDFTPTQTPYT
                     LISAKSEDSRENLQALLLDKIKEIFEAFTLRVPFSKSYKIHDLESVAILEERDYQEDG
                     EVITGYISEKNKWRLEEFYD"
     gene            complement(44209..45093)
                     /gene="miaA"
                     /locus_tag="VQ865_000469"
     CDS             complement(44209..45093)
                     /gene="miaA"
                     /locus_tag="VQ865_000469"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HET3134883.1"
                     /translation="MKTKIIVIVGPTAVGKTALAIEVAKCFNGEVVSGDSQQVYRGLD
                     IGTAKASPEEQAAVPHHLIDVREITESYSAFDFVSEAKMTIEDIHSRGKLAIIAGGTG
                     LYIQSLLEGYHLGGETPHEEILAYRASLEPYSDEELAHLVEQAGLEIPQFNRRRAMRA
                     LEIAHFGQDLENQEILYEPLIICLDDERSQLYERINHRVDLMFEAGLLDEAKWLFDHS
                     PNVQAAKGIGYKELFPYFRGEQTFEEARESLKQATRRFAKRQLTWFRNRMQVTFYQIG
                     ESGVQDRILSQIEEFLDD"
     gene            45214..45384
                     /locus_tag="VQ865_000470"
     CDS             45214..45384
                     /locus_tag="VQ865_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001051775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HET3134884.1"
                     /translation="MAKGFAKGLVTGVAGTVAAVAGAVYAFKKKVIEPEEQKAAFIEE
                     NRKKAARRRVSR"
     gene            complement(45432..46271)
                     /locus_tag="VQ865_000471"
     CDS             complement(45432..46271)
                     /locus_tag="VQ865_000471"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003011065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HET3134885.1"
                     /translation="MTKADTIFKENIERILKEGVFSEQARPKYKDGTVANSKYVTGAF
                     SEYDLSKGEFPITTLRPIAIKSAIKEVLWIYQDQSNSLEVLNDKYNVHYWNDWEVGDT
                     GTIGERYGAVVKKHDIINKLLKQLETNPWNRRNIISLWDYQAFEETDGLLPCAFQTMF
                     DVRRVDGEIYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFINNL
                     HIYDNQFEQAQELLRREPSNCQPRLVLNVPDGTNFFDIKAEDFELVDYDPVKPQLKFD
                     LAI"
     gene            complement(46368..47327)
                     /locus_tag="VQ865_000472"
     CDS             complement(46368..47327)
                     /locus_tag="VQ865_000472"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002919069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HET3134886.1"
                     /translation="MSQKIIGIDLGGTSIKFAILTTAGEIQGKWSIKTNILDEGSHIV
                     DDMIESIQHRLDLLGLAAADFQGIGMGSPGVVDREKGTVIGAYNLNWKTLQPIKQKIE
                     KALGIPFFIDNDANVAALGERWMGAGDNQPDVVFMTLGTGVGGGIVAEGKLLHGVAGA
                     AGELGHITVDFDQPISCTCGKKGCLETVASATGIVNLTRRYADEYEGDAALKRLIDNG
                     EEVTAKTVFDLAKEGDDLALIVYRNFSRYLGIACANIGSILNPSTIVIGGGVSAAGEF
                     LLQGVQKVYDENSFPQVRTSTKLALATLGNDAGVIGAASLVLQ"
     gene            complement(47454..48451)
                     /locus_tag="VQ865_000473"
                     /pseudo
     CDS             complement(47454..48451)
                     /locus_tag="VQ865_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042519.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
     gene            complement(48501..49117)
                     /locus_tag="VQ865_000474"
                     /pseudo
     CDS             complement(48501..49117)
                     /locus_tag="VQ865_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766583.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
     gene            complement(49118..50839)
                     /gene="pabB"
                     /locus_tag="VQ865_000475"
     CDS             complement(49118..50839)
                     /gene="pabB"
                     /locus_tag="VQ865_000475"
                     /EC_number="2.6.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component I"
                     /protein_id="HET3134887.1"
                     /translation="MHRKTVIDFRILGERYTFTQPIKEIKTRNVAEVADLLAQVESYQ
                     EQGYYVVGYVSYEAAPAFEEKLAVHKDPLLGEYLLYFTVHDRVETSPIPLTYEDIDLP
                     SNWQEVTSAADYEKAIAQIHHHLRQGDTYQVNYTVQLKQKLSANPFAIYNRMVVEQEA
                     GYNAYVEHDEMAVISMSPELFFEQNDRELTTRPMKGTTQRGVTDQEDLEQASWLEQDP
                     KNRSENMMIVDLLRNDMNRISEVGSEHVERLCQVEQYSTVWQMTSTIKSQLREDVDLV
                     EIFRSLFPCGSITGAPKIATMEIIKDLEPQPRGVYCGTIGLLLPNGRRIFNVAIRTIQ
                     LHKGQAIYGVGGGITWDSTWESEYREVHQKAAVLYRKQARFQLITTGEISQKNLLFED
                     QHLERLRKASRYFAFPFDAEDLGHKIEEECQDCEANQDYRLRISLSKSGEIEVNRQVL
                     TPLSTSFCQAQVCLQEAALNQSFTYFKTTHRPHLSLGEQEKIYHNKSGKLLETSIGNL
                     VLKIAGKLYTPPIRLGILPGIYRQYLLETGQVEEKVLTLADLAQAEAIYGCNAVRGLY
                     ELSLEEN"
     gene            complement(50900..56542)
                     /locus_tag="VQ865_000476"
     CDS             complement(50900..56542)
                     /locus_tag="VQ865_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000472960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3134888.1"
                     /translation="MFKKDRFSIRKIKGVVGSVFLGSLLMAPSVVDAATYHYVNKEII
                     SQEAKDLIQTGKPDRNEVVYGLVYQKDQFPQTGTEASVLTAFGLLTVGSLLLIYKRKK
                     IASVFLVGAMGLVVLPSAGAVDPVATLALASREGVVEMDGYRYVGYLSGDILKTLGLD
                     TVLEETSAKPGEVTVVEVETPQSTTNQEQARTENQVVETEEAPKEEAPKTEESPKEEP
                     KSEVKPTDDTLPKVEEGKEDSAEPAPVEEVGGEVESKPEEKVAVKPESQPSDKPAEES
                     KVEPPVEQAKVPEQPVQPTQAEQPSTPKESSQQENPKEDRGAEETPKQEDEQPAEAPE
                     IKVEEPVESKEETKTAKGTQEKGHVGEALAQEQLPEYKVTEGTLVETSTTDLDYKTET
                     TEDPTKYTDEETVLRTGEKGSQVTKTTYKTVEGVKTDQVLSTSTEVTKEPVNQQVIRG
                     TKPIEGTLIEESLEKIPFKEVVKEDDQLKKGLEVVAQEGKEGQKKITKTFNTIKGVKT
                     EDAPKVTEEILEEPQDKILKRGTKSFEKPVLTITEIESKDLKRTSDVKYSLENPSKAA
                     IKSITLTLKKGDEIVKTLNVSPEDLTTTLTDLQYYKDYKLETKMVYDRGEGDEEEVLK
                     EEPLRIDLKKVEIKDIIRTDLIKYENQVETDETRLTSVPTDLSNYYLKVTSNDHKTNL
                     LAVQKIEESTIDGKQVYKVIAVADNLVQRNVDNRFEETYTYYIEKPKASQAGIFYDFE
                     ELIQAIQTNPAGEFKLGQSMSARNVVPKGKSYITSEFTGKLLSDGDKRYAIHNLEHPL
                     FDKIKAGTVKNINFENIDIDLSNQDNIAAIANEISGTTRIENIKAIGTITARNNVAGF
                     VNNIKEDATLENVAFIGSINSAGNNSTVGGIAGSNYMGFVNRAYVDATITANNANASM
                     LVPFVQYKAHSWLSGTKGKLTNSVAKGILDVKNTKYVGGITSKTWPYGAVQDNVTYAK
                     VIKGQEIFGSNDVNDGDANPFVSNLFGVIGYSSSEDGTGKDNKNKNKLKHLSKSEADA
                     KVASFNITAAKFVSEPYELNKLNNVSSREAAYESIQDYNADYKLAYKNIEKLQPFYNK
                     DFIVNQANKLDKNNKLNTKEILSVTPMNNNNFVTDLGDANKIIVHYADGTKDYFNLSS
                     SDEGLSNVREYTITDLGIKYTPNIVQKDHSALINGIVNILSPIELQSNPIYQKLGRTG
                     SNRVNAIKDLYLEESFDHVKANLNILVTKLVENEDHQLNNSSAAQQMILDKVEKNKAA
                     LLLGLTYLNRYYGVKFGDVNIKELMLFKPDFYGKNVSVLDRLIEIGSREDNIKGHRTY
                     DAFSEIISKTTLSENLVNFLNYNRRLFTADVNIYDWFKKATEGNVYIAERASEVDEIK
                     AAKYKVWDNLQSATHRKMILPLLNLNKSHVYLISNYSAMAVGTAEKLGHSSFDGIKNQ
                     IEKAADSYRNYFDFWYRLSLDKVKNMLVKNTVTPLWEGYQAPGGWPDKYGKRNNKEDY
                     APLRELFGPIGKYYGNNGTGAYAVIWDNPLDTRTEVNYIALSMIDEFGISVYTHETTH
                     VNDRAIYLGGYGRRSGTHAEAYAQGMLQTPVPSTWFDEYGALGINMTFYRPNDGNQWY
                     ITDPKTLKTREDIDNYMKGYIDTLSLLDYVEGDAVISKHDDKLNQLWFKKVDPIERTV
                     GSKDQYDKVRNMSSDDWKGITLNSVNDLVDNNLMTNRMMNNNIYKPEVFDPGIAYVGI
                     KMMNSIYAGNTSDGAPGAVTFKNNAFRLWGYYGYDKGFLGYASDKLKSQANKEGKQFG
                     DQYIIQKISDGRFQSFADFKKEYYKELLEKANAGFTPFTIDGETIHNYDELKSLFAKA
                     LEEDMVTNKVNGKLVQVKEKVYKKLLQQTNSFKTSIFK"
     gene            complement(56564..57127)
                     /locus_tag="VQ865_000477"
     CDS             complement(56564..57127)
                     /locus_tag="VQ865_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HET3134889.1"
                     /translation="MNETQIQRETRQVVEDVLEKTNLKQGVLFVLGLSSSEVLGGQIG
                     KESSQEIGELIVETILGILGSRGIHLAVQGCEHVNRALVVERQVAEQFDLEIVSVHPT
                     LHAGGSGQLAAFKFMQDPVEVEFIKAHAGLDIGDTAIGMHVKHVQVPIRPILREIGHA
                     HVTALASRPKLIGGARAHYPQDAIRKS"
     gene            complement(57243..58934)
                     /locus_tag="VQ865_000478"
     CDS             complement(57243..58934)
                     /locus_tag="VQ865_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3134890.1"
                     /translation="MKRSSLLVRMVISIFLVFLILLALVGTFYYQSSSSAIEATIEGN
                     SQTTISQTSHFIQSYIKKLETTSTGLTQQTDVLAYAENPSQDKVEGIRDLFLTILKSD
                     KDLKTVVLVTKSGQVISTDDSVQMKTSSDMMAEDWYQKAIHQGAMPVLTPARKSDSQW
                     VISVTQELVDAKGANLGVLRLDISYETLEAYLNQLQLGQQGFAFIINENHEFVYHPQH
                     TVYSSSSKMEAMKPYIETGQGYTPGHKSYVSQEKIAGTDWTVLGVSSLEKLDQVRSQL
                     LWTLLGASVTSLLVCLCLVWFSLKRWIAPLKDLRETMLEIASGAQNLRAKEVGAYELR
                     EVTRQFNAMLDQIDQLMVAIRSQEETTRQYQLQALSSQINPHFLYNTLDTIIWMAEFH
                     DSQRVVQVTKSLATYFRLALNQGKDLICLSDEINHVRQYLFIQKQRYGDKLEYEINEN
                     VAFDNLVLPKLVLQPLVENALYHGIKEKEGQGHIKLSVQKQDSGLVIRIEDDGVGFQD
                     AGDSSQSQLKRGGVGLQNVDQRLKLHFGANYQMKIDSRPQKGTKVEIYINRIETS"
     gene            complement(58931..59668)
                     /locus_tag="VQ865_000479"
     CDS             complement(58931..59668)
                     /locus_tag="VQ865_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3134891.1"
                     /translation="MTYTILIVEDEYLVRQGLTKLVNVAAYDMEIIGQAENGRQAWEL
                     IQKQVPDIILTDINMPHLNGIQLASLVRETYPQVHLVFLTGYDDFDYALSAVKLGVDD
                     YLLKPFSRQDIEEMLGKIKQKLDKEEKEEQLQDLLTNRFEGNMAQKIQSHLADSQFSL
                     KSLASDLGFSPTYLSSLIKKELGLPFQDYLVRERVKQAKLLLLTTDLKIYEIAEKVGF
                     EDMNYFTQRFKQIAGVTPRQFKKGEDR"
BASE COUNT        17713 a        13110 c        10817 g        18173 t
ORIGIN      
        1 actcgactct ctccttcaag aaacacgtgg tggtcgtaac catgcatata tgacagttga
       61 ggaagagaaa gcctttcttg cccgccattt gaaggctaca gaggcaggag aatttgttac
      121 aattgatgcc ttatttcagg cttataaaaa ggagttaggt cattcctaca cacgtgatgc
      181 cttctatcaa ctgttgaagc gccatggttg gcgaaatatt acgccacgtc cagaacatcc
      241 taagaaagca gacgctcaaa ccattgttgc gtctaaaaat aaaatctcaa ttcaagaaga
      301 caagaaagcg ttttaaatat agtagacgtt ttcataaggt tcgcttgatg taccaagatg
      361 aggctggttt cggtagaatc agtaaactgg gatcttgttg gtctccaata ggagtaggtc
      421 cacatgtcca tagtcactat atacgagaat ttcgctatta ttatggagct gttgatgcct
      481 atacaggcga atcatttttc ttaagagctg gtggatgtaa tactgagtgg atgaacgtct
      541 ttttagaaga gctttcacaa gcttatccag atgattattt tttactcgtt atggacaatg
      601 ctatatggca taaatcaagt accttaaaga ttccgactaa tattggcttt gcatttattc
      661 ctccatacac accagagatg aacccattga acaagtgttg aaagagattc gtaaacgtgg
      721 atttaagaat aaagcctttc gaactttgga agatgtcatg aatcaacttc aagatgtcat
      781 acaaggactg gagaaggagg tgataaagtc catcgttaat cggagatgga ctagaatgct
      841 ttttgaaagc agatgagtat tatatgcaat ttctttatat aaaaagaccg gattgctccg
      901 atctttcaat agttcatatt ctcaatttct attttaaaaa tagctaaggt taacgtcaaa
      961 tgactacgcg acctatttca tacgataaaa atcaagcact agaccagcag gtccttgaac
     1021 taataaggac tctgttcccc aatcggttac agttggtccg tgtaaaacct ttataccaag
     1081 ctcgttcaac cgtttgtagt tctggtctac atcctcaacc tcgatatgaa taatgattcc
     1141 tgactgaaag ttttccaaag gaaccaaatg attttgtgac aacataaggc agtgactacc
     1201 aatcgtaaac tgagcaaaac catcatcagc ataatctgcc tttttatcca agatatgctc
     1261 caagtcagca cagacttggg gaacatttga aacgataata tctaattgat ttaaattcat
     1321 ttactctcct ccataaaaag accggattgc tccgatcttt taaagttctg ctctatgaaa
     1381 atcaaagaat aaagtctaca agtttcatat ttgattttcg gcgagaggaa ttatttaatt
     1441 gcgcgtgatt gcaatccttc ttcttccaag aagagacgga atggtacgag ttcttctgct
     1501 tcgtattttt ccttgaaggc tttgatagct tcttctgagt gaagttttgg atccaattca
     1561 agtacttcta ctggaagtgg acggtgttga gtgatgcgag catcgatgac aacagtttta
     1621 ccttctttgt tcaatttaac agcttctgca acaactgcat cgatgtcttc gatacggtca
     1681 actgtgaatc caacagctcc ttgagcttcc gcaattttag cgtagtcagc gtttgtgaag
     1741 tctacaccaa acaagtgttt gtttgtatct tcgtatttgt tcttgatgaa gccgtactca
     1801 gcatttgaga agacaaggtt gataactgga aggtcgtatt gaacgtttgt gataacgtct
     1861 gggtagcaca tgttgaatgc tccgtcaccc atgatgttcc atacttggcg atctggattg
     1921 tctttcttag cagcgatacc accaggaagg gcaataccca ttgtcgcaaa gagtggagat
     1981 gtacgccaca tgttcttagg tgtcatgtga aggtgacgag tagatgtttg agtagtgtta
     2041 cctacgtcga ttgagtagat agcgtcttga tcagcatgtt tgttgattgc attgtaaact
     2101 tgatacaatt gcaattcacc ctcagtttta ccttcgagtt tgttcatgta atcacgccag
     2161 ttttgattgt tcttaacgtt tgcacgccac catggagttg attcaactgg gtttactttg
     2221 tcaaggatag ctttagctgc ttgaccagca tcaccaagga ttgaagcgtc aagggcatga
     2281 cgtttaccaa gtttgtaagg gtcgatatcg acttggatga atttttcagt gttcttgaat
     2341 gcttcgtaaa cttcagcgaa tgggaagttt gaaccaagga aaagaactgt gtctgcttca
     2401 aagaccactt cgttggctgg tttccaacca acacggtaag cagaacctgt caaaccttca
     2461 tagttccatt cgaaagcttc aaagttttta ccagttgtga tgattggtgc tttgatttta
     2521 cgtgacaatt cagtaatcac ttcaccagct ttaacaccac caaatccagc atagataact
     2581 gggcgttcag cattgttcaa gatttcaaca gctttgtcga tttcaacttc gttcaaagca
     2641 ggagcgatga atgagcgttc gtatgaacct gaaccgtagt atgagttttc atcgatttct
     2701 tggaaaccga agtttactgg aatttcaaca acagctggac cttttttaga aactgcagca
     2761 cggcaggctt cgtcaattac ttttggcaat tgctcagcgt aagctacacg tttgttgtaa
     2821 acagcgatac cgttgtacat tgggttttgg ttaagctctt ggaaagcatc catgttcaat
     2881 tcgttaactg gacgtgatcc aaggatcgct aggaatggag tgttatccat agctgcatcg
     2941 taaacaccgt taatcaagtg agtcgcacct ggaccacctg aaccaactgc aaccccgatt
     3001 gagccgccga atttagcttg cataaccgct gcaagagcac ctgtctcttc gtggcgaact
     3061 tgtaagaaac ggatatcttt gtcttcagcc aaagcatcca tcaatgagct gagtgttcct
     3121 gatgggatac cgtagattgt atctacgccc catgttttca atacgttaag cattgctgca
     3181 gatgcagtaa ttttcccttg agtcataatg ataactctcc ttcaattttt ttaaacttgg
     3241 agaatacgat tacatagaat tggaaacgtt ctccaaattt ttactattcc actgtatcat
     3301 atttatgctg acttttctaa aaatctgctc aaaactctct attctctatt ctaatacagt
     3361 tttgaaagtg ttgtcatttc tgttttataa caaagaaatc tagtcattac ttttagtcta
     3421 ttttactaaa atttaacaga agggaactgg tcagaacaga tacagaacta aaggccatgg
     3481 ctagacctgc caattctggg ttgagagcca gtccaacacc tgaaaagact cctgctgcaa
     3541 tcggaattcc gacaacattg tagataaaag cccagaaaag attgagtaga attcgatgaa
     3601 aggttttctt actcatatca aaggcacgaa ccactcctaa aagattattg gttgtcaaca
     3661 ccaaatctgc tgactcgatg gcgatatctg ttccagctcc catagcaatc cccacatctg
     3721 ctacactaag ggcaggagcg tcattgatac cgtccccaac aaaggctact ttccctgact
     3781 gttgcagttt atggatttca tgggcttttt cttctggcaa gacgcctgca atgacctctt
     3841 caattccgat ttgatctgca atagcacgcg ccacaccagc attgtctcct gtcagcatga
     3901 ctgttcggag accacgtttt tttagctgac tgatgactag cttagcattt tccttaggaa
     3961 tatcttgcaa agcaagcaag cctttgattt cattgtcaac agctaagaac acaactgtct
     4021 tagcttcttt ttctagttct tctagtttat cttgataagt attagaaata tccatgccat
     4081 ccagcatttt agcatttcca agtaaaactt gttttccatt gattcgccct gaaacacctt
     4141 tcccgtgcaa ggcctgaaaa ttttcaacag tttgaaactc aagtccagct tcactcgctc
     4201 gcttaacgat agcctcagcc agtgggtgtt gagaagcatc ttccaaggag gctgccaatc
     4261 caaacacttc tacttcgtcg ccgatgatat ctgttaccac aggtttccct tccgtcaaag
     4321 tcccggtctt atcaaagaca agagtttgaa ctttctggat ttcctgtaag acagttccat
     4381 ttttgaggag aacccccatc ttggcactac gtcctgtccc caccataagg gctgtcggtg
     4441 ttgcaagtcc caaggcacaa ggacaggcga taatcaaaac cgccactccg tagagaagag
     4501 aggacacaaa gctagctcca agcacgacca cactatccct gagcaagacg aaccaaaccc
     4561 aaaaggtcat gattcctaaa atgacaacta ctgggacaaa aatccctgaa atcttatccg
     4621 tcaagtcctg aatcggcgca cgacttgtct gagctttctt cacaaaatcc acaatctgag
     4681 ccaaaacagt ctctgagcca actttttctg ctctaaagac aagcgttcca ctatgattga
     4741 tggttgagcc aatgacagta tctccaactg tcttgtccac aggcagactc tcacctgtca
     4801 ccatggattc gtcaatacta gagacacctt ctactacgac accatcaaca gcaatctttt
     4861 caccgggacg cactcgaatc aggtcgccta ccttgacttg ttccaaagga acttggacat
     4921 aactatcatc actcaagact tctgcggttt tagcttgcaa gtccagtaat ttctccacag
     4981 cttgggacgt attttttctc attttttcct caaaaactgc tcccaaaaga acgaaaaaga
     5041 ggataaatcc agcactttcg aagtaaacag ggagaccagc aaagagagca actaggctat
     5101 agaaataagc cactagagtt cccagcgcaa ccaaggtatc catgttggca ttgtgctttt
     5161 taaaactggc ccaagcactc tggatatatg gcttacctgc aactaacata ataggcgttg
     5221 ttgctagaaa ggttccccaa tgcatgactt gatgactaat gctacctgtc aacatcccaa
     5281 tcatgagaat cacaagaggc acagtaaaga tactagtaat ccaaaaacgt tgcaggagag
     5341 atagagattt tcgagtcttc tcaacgacta tatagcttcc cttttgcatc ttcatgccac
     5401 aagaaaattc atgtcgccct aattcttgag gtgtaaaacg aatgactttc tcctcatcta
     5461 cgccgattgg ttccaagata ccttcttctt caaacagaat ttccttataa cagtttgaag
     5521 gagtagcacg atgaaaggta atctcagctg gaattccctt ttgaagctgg atatgggctg
     5581 gatgatagcc tttttcagct cggatacgga ttttttgaat gccattttct aagcttgctt
     5641 tcacaatttc tgtcatagtc tccacctact ctacaatcat cttgccgtgc atcatgttca
     5701 taccacaagc aaagccaaac tctccaacct gctcaggcgt gatttccact acatactctt
     5761 cccccattgg caggttcgca tgtacaccaa aatctggaaa aacaatttga tccagacatg
     5821 gtgaaggatc cttgcggtca aagacaatgc gtgctggcac tgatttcttg aggacaatca
     5881 actcaggagt atagcctccc atgacttcca ctcgaatctc ttggtatccg tttttttgct
     5941 gggctttttg tccagatttt tcaggctttt tgaaaaacca aaacaagata aacgcgataa
     6001 gggcaataca aataatggtt acaatactat ttaacatggc gtctccttta catacaatta
     6061 catcttactt ctgttacagc acttgatttc ttctctgaaa tcacagcttc caagtcttcc
     6121 aagtcagtct gagtaaattc acattctaca atcaagtcag ccaacaaatt cctaatccta
     6181 cgggaacaaa ccttgtcttt gatatcttgg acaagtaaat cccgactttg gtctagagtt
     6241 aaaagcgctg aataaacaaa ggacttgcct tcttttttcc gagtcagaca ctctttctca
     6301 accaaacgag ccaaaagagt ttgaatggtc gacttggacc agtcgaaccg ctctgccaaa
     6361 accctaatca aatctgtact ggtctgctcc ccctgcatcc aaataatctt catgacctgc
     6421 cattctgcat ctgaaatctg cattaccata cctccaaaat ctacatttgt caattacact
     6481 catcagtata ctcttaaaat ctacatttgt caattataga aataatattt tcttcgaaaa
     6541 atagaatttt aatcatttga aaaacgattt gcagtcaaat attactatat aaacaataaa
     6601 aatatgctat actaaagaaa aaagaaaaca accactaggg gtgcgtaaag ctgagattaa
     6661 cgactgttag atccctctga ctcaatctag gtaatgctag ctgatggaag tggaaatgat
     6721 aatggggact agcagtcttc tattgccttt ctaaaacaga ctagcttgtt cttaagaata
     6781 caaacttcag ttggttggga ggttttagat gacttattta cccgttgctt tgaccattgc
     6841 agggactgac cctagtggtg gtgctggcat tatggcagat ttaaagtcat tccaagcgag
     6901 agatgtctat ggaatggctg ttgtaaccag tcttgtcgct caaaatacca gaggtgttca
     6961 gctaatcgag cacgtttctc ctcaaatgtt gaaagcccaa ttggagagtg tcttttctga
     7021 tattccacct caggctgtaa aaactggaat gttggctact actgaaatca tggaaatcat
     7081 ccaaccctat cttaaaaaac tggattgtcc ctatgtcctt gatcctgtta tggttgctac
     7141 aagtggagat gccttgattg actcaagtgc tagagactat ctcaaaacaa acttactacc
     7201 tctagcaact attattacgc caaatcttcc tgaagcagaa gagattgttg gtttttcaat
     7261 ccatgacccc gaaggcatgc agcgtgctgg tcgcctgatt ttaaaagaat ttggtcctca
     7321 gtctgtggtt atcaaaggcg gacatctcaa aggtggtgct aaagatttcc tctttaccaa
     7381 gaatgaacaa tttgtctggg aaagcccacg aattcaaacc tgtcacaccc atggtactgg
     7441 atgtaccttt gctgcagtga ttactgctga actagccaag ggcaagagtc tttaccaggc
     7501 agttgataag gccaaggcct ttatcacaaa agctattcaa gatgcccctc aactcggtca
     7561 tggttctggt ccagtcaacc atacaacttt taaagattaa gaaaaaaact ctctagttcc
     7621 cactttaagg gaattagaga gtttttatac tcttcgaaaa tctcttcaaa ctacgtcagc
     7681 ttccatctgc aacctcaaaa cactgttttg agctgacttc gtcagtctta tctaaaacct
     7741 caaggcagta ctttgagcaa cctgcgacta gctttctagt ttactctttg attttcattg
     7801 agtattaatt aggaaagaat gtcatgcaac tttgttaaaa aggcttgcgt ttttgcctca
     7861 atatcttctg cttgcatcaa atcacgtaca acagctacac cagctatgcc agtgcccata
     7921 agctgatcaa tattctccga agtcaagcct ccaatagcaa ctactggaat ggcaaccgtt
     7981 tggcaaattg ttttcaaggt cgatatcaga gtaatgggcg cattttcctt ggtggtggtt
     8041 gggaaaatgg ctcctgtacc caagtaatct gcacctgatt tctccgcttc cagagctctt
     8101 ttaaccgttt tagcggtgac accgaggatt ttttcaggac ccaagacttt gcgagctacc
     8161 gaaactggta attcatcatc tccgatatgc agacctgctg catcaaccgc aagacaaaca
     8221 tccaaccgat catcgattat caaggggacc tgataggcat ctgttatttc cttgacttgt
     8281 tttgccagtt gataatattg attggttgtg agattttttt ctcgcaattg gactatggta
     8341 acccctgaac ggcaggccgt ctcaactttt gcaagaaagc tttccacgga atcttgatag
     8401 cgattggtta ccagatatag tctaagtgct tctctattca taaacctctc ctttgatggt
     8461 atctagccaa ttttcatctc ttcttaggag cgaaagctga ttgagtactt ggtaacgaaa
     8521 ttcttccaat cccattcctt gaacaactat tttctcagca gcgatattga gataagagac
     8581 tgctaagcaa gaagcttcaa aaccagtctt tccttggctg agaaaaacgg ctgttaaggc
     8641 tccaaccaag tctcctgtcc ctgttatcca gtctaattca gtacagccat tctccagtac
     8701 agcaacttga ttctccgaaa caataaggtc cttggggcca gtaactaaga aagacatacc
     8761 aggataggtc tgacaccagt ctttcaagac ttgaagcaaa tcctccgttt cttgatcttt
     8821 agcactcgca tcgaccccaa cgccgtggtg ctttaatcca acaagacttc gaatttctga
     8881 catgtttcct ttaaggaccg taggtctata gtctaaaagg tctttaacta agctcttacg
     8941 aatggatgaa gtcgttacgc caaccgcatc tactaccatc gggagagaag attggtttgc
     9001 atacgaagct gccatgcgga ttgctttttc cttctcagct gacaaatgcc ccaaattgat
     9061 gaagagagcc tgactttgct tagtaaaatc aagaacttca cggggatcat ctgccatgac
     9121 aggtttgcat cccagagcca aaatcccatt tgccagcatc tcacaagaaa tctcattggt
     9181 catacagtga atgagggaac tagagcctat aggaaaagga tttgtcaatg cctgcatcat
     9241 tctatccttt cagcaaagaa atatccttgc acttttttaa agaattcctg cttgattaaa
     9301 aatctaaatg caataaagga aatcgctgta ccaatcaagg ttgctccgaa aaatcgagga
     9361 gtgtagataa accaactaag cttagcagcc gatcctgtaa agagcaccat aacaggatag
     9421 gaaacaatag aaccaataat acctgttccc acaatttctc ccaaggcaga aaagtaaaat
     9481 tttcgaccgt acttataaaa gagacctgct agaagggctc caaaagtcgc tcctgtgaga
     9541 gctaaaggcg gaatcccttg agtcgtcata cggataaagg ctgtcactgt agccatagcc
     9601 aaggcataaa caggtcccat catgattccc gctagaatat tgactacact ggacatcggt
     9661 gccattccct caatccgaaa gataggtgta aggactacat caagggcaat catcatagat
     9721 aaaatggtca atttgtgaac ttgtagttgg tgctttctca tgtttctatt cttctccttt
     9781 ttctaaagac tgtaaatcgc tcttccatgt ctggtgttgg taagccatct cccaaaactt
     9841 agcttccata tgaacactga tgtggaaggc atctagcatt ttttgcttat ctgtctcatc
     9901 actttctcga taaagctgat tgaccagtgc tccctcctct ctgatctgtt gctctaactc
     9961 atccgtaata taagtttcaa tccattgttg atagagagga tttggtgatg gtttaagatt
    10021 aagtgatttg cctatatcat ggtataacca aggacaagga agcaagcttg caaaagctat
    10081 ggctaagttc ggttctgcaa attgcctata aatatgagaa atgtaatgat aacaggttgg
    10141 agcgattgga tgttgctcca tttcctggtc gttgatttcc aattccttga aaaattgttg
    10201 gcgaataaat aactcaccct ccactaaacc ctgagcattt tgtttcaaga gtcttttcat
    10261 ctcttggttt gaagtcttat cagccaaaag atgatagatt tctgagaaag ccttcagata
    10321 gtaggcatcc tgaatcaggt aatagcggaa aatggcaggt tctaaattcc cctcttgtaa
    10381 ttgtaaaata aagggatgat gaaaggaagc ctgccaagct ttcttggata attccatcgc
    10441 aatatctgta aattccataa taactccttt ataaaaatag actggtttga agcaataaaa
    10501 agaaaagcag gtagattaat tttgtttttt taggaatata aaaagtccga tagctattct
    10561 tcaactgtgc atgttcgtca tatccgtgag cagatagagc tctcaggtaa agatggcgcc
    10621 acctaaagac tgtcatcaga accttactgt aaatcaaggg cgaccaaaaa tgtagttttt
    10681 gaccacgtaa taggcaagct tctttgaggg acttgatttc ttgctgaatg agaggaaaag
    10741 aattgaatac cacaatcaag gcataggacc aagagcgtga tagccccttt tgagccaagt
    10801 acaagagaag ctcttttagt gaaatagagg aaacaaagac aaggccgata caaactgtca
    10861 caaaggccct cgttccaagc atgactgcct gtgaagcatc tccgtgtaac tgaactgccc
    10921 agtagttggc aaaagatggt aaaatggcaa gtatgatcat ccaagctaac attttaaatc
    10981 gacggtaata gagcataaag agaatacaaa atgcgactac cgaaagattc agagcaatcg
    11041 aaggaatgaa agatgtttcc aaggataaaa tcagcaagaa gagactgata atcggtgtct
    11101 gggttgctac tttgaccata ctatctcacc tccccttggg tattgctact ctgagatgta
    11161 agtggtttgg taatggtcac ttctttcaca tgccgaagac cctgactagt catctcaatc
    11221 caataatcaa ccacagaaat caaagggtct aaacgatgac taatgagcag aaaacttctt
    11281 ccttgattcc tctcctccac aatccacttg caaaaataat ggcaggctct atcatccaaa
    11341 cctgcaaaag gttcatctag caagatcacg gaagccttac tggtcaagat ggtcaggagc
    11401 tgaagaattt tttgctgacc accacttaat tgatagggac tcttatcgac tgcctgctcc
    11461 aaatcaaaat atcgtaaagc ttgaaaaatc cgctgatttc tttcagaatc aggtccatct
    11521 aattgaagct cctctcgcag actgactcgg ataaactgct tctcagcttc ctgaacaaca
    11581 cccgtcagat cacggtacaa actctttttc tttttcagga ctgtcccctt ccatgcaatg
    11641 cgccccttat acttttgaaa ttgaagaata gaccgaaaga gggttgattt cccgacacca
    11701 ttgtcaccca ggatacagga aatcccttga tagaatgtga aatcagcaat tgaaaagagg
    11761 gggcgattac caagctcacc agtcacacgg ttcatatgga ataattccgg gctagaagca
    11821 acttcctttg aagcaacctg tgtcatctca taggaaggga tttgatttat ttcccttagt
    11881 tttccgtctc ttagctcaac catatggtcg atataggctt tatagtcaga taaatcatgg
    11941 tcgcacaaaa taactgtctt cccatcaaga gccaactctt ttagaatctc caatatctcg
    12001 attctgctct tgcggtcaat ggaagcgaag ggctcatcca agagatatac cctaggattc
    12061 atggcaaaga ggacagccag cgctgctttt tgcttttccc cacctgatag gtgatgaatg
    12121 ggacggtgta agattgcctc gcaacgacat tgctggacaa cctctgctat tttagaatca
    12181 atttcctgaa ggtgatagcc gatattctcc aaggtgaaaa tcaactcctc aaacaagttc
    12241 tccatggtaa attgatgatt gggattttgc aagagaatgc caaccttctg gacacgtgcg
    12301 atgatagaaa gctgactgac ctcgctccca tctatcagga cttgaccact atagggaaga
    12361 gaactgactt gggcaatcat ttgaaagagg ctggattttc ctgaaccact gctcccaact
    12421 aacaaggtaa aggcttgcgc atgaaaagta aaatcaaacg gctcagagaa gattggggac
    12481 tgaatcgctc gtagttccag acccatctat gcttttcctc cagttgcaaa ctgatgatag
    12541 agtttgacaa tggcacgaac caagatggta cagaagaaat aaacagaaat aaaacgtacc
    12601 acaagcaagg aaaggacaaa cggaagggaa aaggcgtagt aacctaactt aatgtattca
    12661 tagacaaagc taacaagcgt aatcccaata ctattagcag ttagagagag ccaactttca
    12721 tagcgattct tagttacgat aaaaccaaat tcacttccca aaccttgaac caagccagac
    12781 aaaagagctc ctagaccaaa ttggctacca taaaggactt cagcaagcgc agctagcact
    12841 tctccaatcg ttgcacttcc gactctcgga acaaagatgg cagcaatggg cgcagccata
    12901 caccagagac cgaagaggat ttcattggca aaggcctgca aaccaagagg tgttaagagt
    12961 agactgagaa tattatacac atatcctgaa ccaacgaaaa ccccaccaaa aaagatagac
    13021 aagaaagcaa gcaagataac atcttttaac tgccattttt tcaacataaa aaactccttt
    13081 ttttaaagaa aagtggggca ctcaagaaga ccgacctaaa tactttgtat agcagactga
    13141 atttagaaca gtacacaaga acactaaaat atttctagaa attaatttga attttctaat
    13201 tgatttgttc gcatcttatt tcaatctact atatcatctt catccagttt cgtaaaagaa
    13261 aaaactctaa ttacagatac gaattagagt tcagcttaca agattagaca gttcttttcg
    13321 acatacgaaa aaaacatttc acatttccct tcgccagtct taactgtatc aggttcaatg
    13381 ggtatcatct cagcctaaag caccccaaat gcctttatta tttaattatg tgattattat
    13441 aacacacatt ttatactagt tcaagaaatt gaactggaaa tacagccttg cactcacaaa
    13501 gacagcagat ctttcttttg caaaaaacaa atgacctgtt tgatgaatta gctattcaag
    13561 ctgaatctag acatagcttt ttaaaaaagg aaaatcctac ttacttagaa tccaaggata
    13621 gatatctatt gttcactcat ttcccgaaca gttttttcta tattttttgc atacgatatt
    13681 gccgaaatga ttgaaacgcc gtcaacattg gtctttataa tgtctttaat atgtttcgtc
    13741 tgtatcccac caattgcaac taaaggcatt tgtggcaata gttttctcat caattcaaga
    13801 ccttcataac ctatagcacc accagcatca tcctttgact gggtatcaaa tacaggacca
    13861 acaccaacat aatctacata ttcaactttt gattgttgaa attcttcctc gttttttata
    13921 gaaagaccaa ttattttatc tggcatcaat tttctaattt catcaacacc aatatcatct
    13981 tgacctacat gtacgccatc agcgtcaatt tccattgcta aatctatatc gtcattaacg
    14041 ataaatggaa cattgtattt tttacaaagt tctttaattt ggatagctag ctcaagtttt
    14101 tctaagcctt ctaaagcacc ctcacctttt tctcgaaatt gaaataaggt tataccacct
    14161 tttaaggctt cctcaacgac tgtatataga ttttttcctt ggcaagtagt cgttccacaa
    14221 ataaaatata gttttagtaa ttctttatga aacatcttac ttcactcttt tgaatttctt
    14281 gacatcttca tctgtaattt catataaggc atttataaat tcaactttaa atgttccagg
    14341 aagatgtcca tttggacgtt tttccgccat ttctccagcg atattgtaaa ccaacattgc
    14401 tgtttctaat gatttcaatt cttgaccttt ttcaagtccg ataaagcttg ctactacagc
    14461 tcctaataag catcctgtcc caatgacttt cggcatcata gcactaccat tatgaatcgt
    14521 taccacttct ccattaacag caatggcatc cacttcacct gttactacta ttggaatatt
    14581 gaacttctca tttgctgcta gagcaatttc gtcaatatta tctacgcccg cactatctac
    14641 tcctttagat gccacatcta ttcctactaa agaggcaatc tctccagcat tccccctaat
    14701 cgcagctagt ttgtaattgt tgattaaatc atctgctact ttttttctat attctcctgc
    14761 tccacaggct acaggatcta aaactgctgg gacattatat ttctctgcaa ttttcagagc
    14821 agcttggtat aatttccaat tttcatctgt caatgttcct atgtttatta ataaaccacc
    14881 agcatacttt aataagtcct ctaaatctgc tggaaactca ctcatggctg gtgaggcgcc
    14941 cagtgctact aatccatttg ctgtgaaatt ttttactaca tcattggtga tgcaaatgac
    15001 caaaggtgct ttttctttta ataattttaa acttgtcata ttgaaatcct tccttttcac
    15061 tttatacgat ctactaattt cgatttatct ttagttgaga atttttttca tttacattga
    15121 atgatttata ctcaatgaaa atcaaagagc aaactaggag gctaaccgca ggttgctcaa
    15181 aacactgctt tgagcctgta gataagactg acgaagtcag ctcaaaacac tgttttgagg
    15241 ttgtggatag aactgacgtg gtttgaagag attttcgaag agtcttacct catcaaattt
    15301 gtaaatatca tgagccttct ctagacatcg taaccaatat caaaaaaagc taattctaaa
    15361 gcgactgctt gattccagcg ttgctgaagt tctgtcaaat cttctcgatt tttaccgaca
    15421 cgattgagtt catcaaccag aaattgaact cactctgcaa agaaaggacc tctgtggaga
    15481 ttgatccatt ccgaatgaat atagacttca ggtagagcca aatctttaga accccagtct
    15541 aaatagagac cttctgcaat gaccagcata accaaaagat gggcatagtc tgatgaagcc
    15601 actgcccaat acattagatc ctgaaaggct tttgttacag ggtgcaaagt cacttctaga
    15661 tagttattct ctgctacttt taactcttta aaagcctttt ggaaataacc atcttcatct
    15721 gcttcaagaa agcctagttg cttggcaaaa cgaagcttgg attcaagttt atctgcgtga
    15781 gctacgcagg cacccagcat ggataagaag gcatcaaaga agtgataatc ttgaatcaga
    15841 tagtccttta agaccttatt ctcaattgtc cccgcaaaaa gttccttaac aaaacgatga
    15901 ttgattgcag cctgccaatc cttctgactg ctttttaata attctccaac agtcaaacct
    15961 ggctgaaatg catagtcttg tgtttccata tttacttctc ctctctttac ttgttagtaa
    16021 ttaataaaac agcaagaaat atcaagcaaa atcgtaattc cacttgatcc ttttaaagca
    16081 catcgagagc atttacagag agctaactaa acaagcctat ccagtttata taaacaaaaa
    16141 actccaatta caatcaagaa ttagagttga cttacaagat tagaccgttc atttcaccat
    16201 acgaaaaaac tgttcacatt tcccttcgcc agtcttaact gtatcaggtt caatgggtat
    16261 tatctcagcc taaagcaccc caaatgtctc tattatttaa ttactgaacc agtatagcaa
    16321 aaaatgaaag ccctagcaag atatttgacc gaaaaatatc tttatataca atatattgaa
    16381 actagaatag tacacctcta cttctaaaac attgttagaa atcgatttaa ctgtcctgat
    16441 tgatttgtcc tattcttatt tcattttact atagttttcg atagcgattt attcttccaa
    16501 tacacgaaga aaaacctcca cattcagtga aggcaatctg ttttatcaat acaattttaa
    16561 gtcacgaggg tcaactggga aggttgggtt gtatggattg tgacggagct taaagtgttt
    16621 gacatcttca atggtctgag ctccagacaa ttgcataact gtcttcaatt ccgcattcaa
    16681 gtgttcaaag acttgacgca caccgacact accaccgaga gccaagccat aaataacagg
    16741 gcgaccaata gctaccaagt ctgctcctga agccaaggct ttaaagacgt gttgaccacg
    16801 acgaacacca gagtcaaaga caatcggcac acgtctatca actgcttctg ccacttcttg
    16861 aagcgagtca aaggcagctg gtccaccgtc gatttgacga ccaccgtggt tggttaccca
    16921 gataccagaa gctcctgcag caagtgaacg ttcaacgtcc tcacggcatt gtggtccctt
    16981 gacatacaca ggaagaccag agtattcagc gataaattct acatcgcgtg gagacaagcg
    17041 ttgtttagct gatttgtaaa caaagtccat tgatttacca gcaccttctg gcaggtattc
    17101 ttcaacaatc ggcatgccaa ctgggaagac aaaaccatta cgcttatcca cttcacgatt
    17161 cccccctaca gtagcatctg ccgtcaagac aatcgcttta taaccttcag ccttcacacg
    17221 gtccatgatg tggcggttga taccgtcatc cttactaaag taaaattgga accaatgggg
    17281 tgtcccttga agggcttcag aaatctctgg aaggtcaaca gtagagtaag agctggttgt
    17341 ataaagagaa ccaaactcat gcacaccacg cgcagtcgcc acttccccct gttcatttgc
    17401 caatttatga gccgcaacag gcgccataat gattggtgaa gatagttttt cacctgcaaa
    17461 ttcaatctct gtacttggat tttcaacatc gcaaagtgta tgaggaacga tgagtttgtg
    17521 gttaaaggcg cggatattct ctcttaaagt gaaagtatct tccgccccac tagcgatata
    17581 gccaaatgct gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat
    17641 gaagtctaca tgaccttctg cattgcttgt tttatatgac ataaaatgcc ctccttgatt
    17701 aagtaagcgt ttgcttttta ctacacaact ataataactc ttttttcaat cattttcaag
    17761 agttttgctt aaaaaccatc ttattttttc atacaatata ctagccctac tttccttaaa
    17821 ctctaaacct tagtctatat taagtgaatc gttgagattt tttgctgcca ggcatttgaa
    17881 ctactttttt atttgcggat tctatctact aatactataa aaaaaacaag tgaataagac
    17941 accagaacat cctctaatag gacctatgga cttatatcag tcccatatat actgtttaag
    18001 caagatacta tcctagttga cgctaacttc ctatcccact tattaatttt ttatttatag
    18061 tgaatctgaa caaatcaatt ggggaatcca agtcaatttc tagtactttt tgaacagttt
    18121 cagcgtacta tcgtaaaatg aaataaaaca tgcacaaatt gattagggaa tttaaaccaa
    18181 tttctaacaa tgtcttagaa atcaaagtgt actatttcaa cttcaatata ctacacttca
    18241 ttttctcctt aaattcagtc tctttttgaa tcaaaaaatc ctctggtaag agccagaggg
    18301 taagaattta tttcattgtt gggaagagca atacatcacg gatagttgtt gtatcagtga
    18361 ggagcatgca gagacggtcg ataccgattc ccaaaccacc tgttggtggc ataccgtatt
    18421 caagagcctc gatgtagtca tagtcgatgc ctgtcgcttc atcatcacca agttctttag
    18481 ctttagcttg ggcttcaaaa cggctaagtt ggtcgattgg gtcgttgagc tcagtaaagg
    18541 cattaccgta ctccttagtc atgataaaga gctcgaaacg gtcagtaaag cgttggtctt
    18601 caggattttt cttagcgagt ggagatacag ctactggatg tccatagaca aaggttggtt
    18661 ggattaaagt ttcttcaaca aactcttcaa agaaggcatt gatgatgtga ccaacctcag
    18721 tgtagtgttt ctcaactgga actttcttct cagcagcgat agctttagct tctttcaaag
    18781 tcatgtcttg ccagaaatcg acaccagtaa tttctctgat agcatccacc atatgaacac
    18841 gcttaaatgg ttcgttaatc ttgatttcag taccttggta gttgactggg ccatcgccct
    18901 taactgattt agcagcatgt tggataatgc cttccgtcaa gtccatgata tcttggaagt
    18961 ctgcataagc ttggtaaact tcgatagaag tgaactcagg gttatgagta gcatccattc
    19021 cttcgttacg gaagatacgg ccaatttcat agacacgttc cataccaccc acgataaggc
    19081 gttttaagtg aagctcagtc gcgatacgaa gcaccatgtc aatgttttgg gcattgtggt
    19141 gggtgataaa tggacgggca gcagcaccac cggcttcatt atgaagaaca ggtgtttcca
    19201 cttcaaggaa tcctttttgg tcaaggtaac gacggatttc agagatgatt tttgaacgag
    19261 tgacaaagcg ttcaaagctt tcacgattag aaatcaagtc aaggtaacgt ttacggtaaa
    19321 ttgtttcaac gtctgtcaaa ccatggaatt tctcaggaag aggacgaaga gccttagaca
    19381 agtgtgtgat gtgggttgcc ttgatagaga gttctcccat atccgtacgc atcacttcac
    19441 cttcgacacc aaggaagtca ccaaggtctg cttttttgaa gatttcgtag ttttcttcac
    19501 cgacagcatc cttacgaacg tagatctgaa tctggccttc gcggtcttga aggtgggcaa
    19561 aaccaacttt tcctttacca cgtttggtta ccaagcgtcc tgcgatagta gctgtttcgt
    19621 ttttatcgtg taattgttct ttatcgaggt tggcatattt atcttttaat tcttgtgaat
    19681 ttgcagtacg ttcaaaacgt tttccgaaag gatcgattcc ttgttcgcgg agcgcagcca
    19741 ttttttcacg gcgaacgatc tgctggtcat ttagttcttc catatgttct gtagacatgg
    19801 gatcctccta gttttactca aaattgaata cgatgagtca ttttttgcga tactcccatt
    19861 ttatcataaa taagcaagaa attcacggat aatctttaaa aactaaaaag aacctgacgc
    19921 taaaatcact ggaaagaagt gaaagtatct tccgccccac tagcgatata gccaaatgct
    19981 gctttaggaa taacttgttg cgccattggc tccaaatcat aggtattgat gaaatctaca
    20041 tgaccttctg cattgcttgt tttgtatgac ataaaatgtc ctccttaata agtaagcgtt
    20101 tactttgtat attataaaaa tatattaact cttttttcaa aacttttcaa atattttgtt
    20161 tggaaatttc agaaatttta tgtctatgat aaaaatcctt ataacggcaa taaaaaatag
    20221 atattatcca aagaagattt taagtgctac aataactgta ttatttctag atgggaggtt
    20281 ctatttttgg attgatccat tgttgaacaa tatctaccac tatatcaaaa ggcattcttt
    20341 ctgaccttgc atattgcagt ttggggaatt ttgggatcct ttctgctcgg tttaatcgtt
    20401 agtatcatcc gacattatcg aatccctgtt ttagcgcaag tagcgacagc ctacattgaa
    20461 ttgtcacgta atacgcccct tttgattcaa ctcttctttc tctacttcgg tcttccccta
    20521 atcgggattg tcctatcttc agaagtctgt gcaacgcttg gacttgtctt tttaggaggc
    20581 tcctatatgg cagaatcttt ccgaagtggg ctggaagcca tcagtcaaac ccagcaggag
    20641 attggcctcg ctattggtct gacacctcta caggtctttc gctatgtggt tcttccgcaa
    20701 gcaacagcgg tggtactccc ctcctttagt gccaatgtca ttttccttat caagaaaacc
    20761 tctgttttct cagcagtggc tttggccgac ctcatgtacg tcgccaagga tttgattggt
    20821 ctctactatg agacagacat tgcgctagct atgttggtag ttgcttatct gatcatgctg
    20881 ctacccatct cactggtctt tagctggata gaaaggagga ccttccatgc aggattcggg
    20941 aatccaagta ctctttcaag gaaataatct cctgagaatc ttacaggggt tgggcgttac
    21001 gattgggata tccatcctgt ctgtcctctt atccatgatg ttcggaacag tcatgggaat
    21061 catcatgacc tcccattcta gaatcatacg atttttaaca cgattgtatc tggaatttat
    21121 ccgtatcatg ccccagctgg tgctactctt catcgtttac tttggcttgg ctcgaaactt
    21181 taatatcaat atctcaggtg agacttcagc tattatcatt tttaccctct ggggaacagc
    21241 tgaaatggga gacttggtac gtggagctat cacttctctc cctaaacatc agtttgaaag
    21301 tggataggca ctcggcttga ctaatgttca actttactac cacatcatca tcccacaagt
    21361 cttaagaaga ctgctaccgc aggctatcaa tcttgtcact cggatgatta aaaccacttc
    21421 attagttgtt ttgattgggg ttgtggaagt gaccaaagtt ggacaacaaa tcatcgatag
    21481 caatcgcctg accatcccaa ctgcttcatt ttggatttat ggaaccattc tagtcttata
    21541 tttcgcagtt tgctacccta tttccaaact atccactcac ttagaaaaac attggagaaa
    21601 ctaaatgtct gaaactatct tagaaatcaa ggaactaaaa aaatccttcg gagacaatcc
    21661 catcctccaa ggactttctc tagaaatcaa aaaaggggaa gttgttgtca tcctagggcc
    21721 atttggttgt gggaaaagta ccctccttcg ttgcctcaac ggcttagaaa gtattcaagg
    21781 tggagatatt cttctggatg gtcagtctat cgttgaaaat aaaaaagatt ttcacctagt
    21841 tcgccaaaag attggcatgg tctttcaaag ttatgaactc tttccccatc tggatgtctt
    21901 acaaaacctc atcctaggcc ctatcaaagc tcaaggaagg gacaagaaag aagtaacgga
    21961 agaagctttg caattactag atcgtgtcgg tttactggat aaacaacata gctttgcttt
    22021 gctttgcccg tcaattatct ggtggacaga agcaacgtgt tgcaattgtc cgtgccctcc
    22081 taatgcatcc agaaatcatc ctttttgacg aggtgactgc ttcgctggat ccagaaatgg
    22141 tgcgtgaggt gctggaactt atcaatgatt tggcccaaga aggccgtacc atgattttag
    22201 taacccacga aatgcagttt gcccaagcca ttgctgaccg gattatcttc ctcgaccaag
    22261 ggaaaatcgc tgaagaagga acagctcaag ccttctttac caatccgcaa accaaacgag
    22321 cccaggaatt tttaaacgtc tttgacttta gccaattcgg ctcatatcta taaaggagat
    22381 tcttatgaaa ctattcaaac cactcttaac tgttttagca cttgcctttg cccttatctt
    22441 tatcactgct tgtagctcag gtggaaacgc tggttcatcc tctggaaaaa caactgccaa
    22501 agctcgcact atcgatgaaa tcaaaaaaag cggtgaactg cgaatcgccg tgtttggaga
    22561 taaaaaaccg tttggctacg ttgacaatga tggttcttac caaggctacg atattgaact
    22621 agggaaccaa ctagctcaag accttggtgt caaggttaaa tacatttcag tcgatgctgc
    22681 caaccgtgcg gaatacttga tttcaaacaa ggtagatatt actcttgcta actttacagt
    22741 aactgacgaa cgtaagaaac aagttgattt tgcccttcca tatatgaaag tttctctggg
    22801 tgtcgtatca cctaagactg gtctcattac agacgtcaaa caacttgaag gtaaaacctt
    22861 aattgtcaca aaaggaacga ctgctgagac ttattttgaa aagaatcatc cagaaatcaa
    22921 actccaaaaa tacgaccaat acagtgactc ttaccaagct cttcttgacg gacgtggaga
    22981 tgccttttca actgacaata cggaagttct agcttgggcg cttgaaaata aaggatttga
    23041 agtaggaatt acttccctcg gtgatcccga taccattgcg gcagcagttc aaaaaggcaa
    23101 ccaagaattg ctagacttca tcaataaaga tattgaaaaa ttaggcaagg aaaacttctt
    23161 ccacaaggcc tatgaaaaaa cacttcacct aacctacggt gacgctgcta aagcagatga
    23221 cctggttgtt gaaggtggaa aagttgatta gtcattaact cttaaaagga actggatttt
    23281 aagatccaat ccctttttaa gattttacct ataacatcct gagtctatct aagatgttca
    23341 atctgaacac agtgtacata ctttatcttc tattgcatat actttatcac ataagatacg
    23401 aatatcctct tcactatgac tagcaatcaa aattgttgtc cctttttcac tagagagctt
    23461 tctaaacaat gttctcatat tttctacact tgatttatcc aaggcattca taggttcatc
    23521 tagtaaaaga atagagggat tctccataat tgcttgagca atccctagct ttttcctcat
    23581 acctagcgaa taagttttaa ctttctggtc tttttgctca tatagaccaa ctattttcag
    23641 tgtatcattg atttcctgat taccaactac tcctcgtatg cttgccaaat attgtaaatt
    23701 cttaaagcca ctataataat ttataaaacc aggttcttca atcaaagctc ccaaattagc
    23761 tggaattttt ctctcaggaa caatattttc cccattgatt aacacttctc cataagacgg
    23821 actatataaa ccagctatta atttaaacaa tacacttttc cctgagccat tcgcaccagt
    23881 aattcctata atttccccct gtttacaact aaagttaagg ttttgaaaaa cacatgtttt
    23941 ttttaattcc aactgaatat tttttaatgt aattatttca ttcattctat aaacctcctc
    24001 ttttgacgag tgaaatagaa aatgctttta aaaagaaaga ctaaaaatag caactgaaga
    24061 aataaatctc gtcctatatc tccattccct cgatttaaaa tataaaatag ataattagtt
    24121 cgatttccta caaatagacc accaaacaca atcatgagta aaaagaagct aacacaagaa
    24181 aagttcattt gctcattcgc tcctagtacg tataacataa agcaaaacaa gactaacaca
    24241 caagcattca aagaatcaac tataaacaaa actcctatat cccagtttgg taactgtaac
    24301 ataaattgaa tcactagaac ttttaccatg attaaaatga gtccataaag aaaacaggtc
    24361 caaatctgat acctaatcca gagcttaata gaagaaaatc gaatcacttc cataaagaaa
    24421 tcggatgctc ttctacgata tacaactgct agaaaaaatg tatgaataat aaaccaatga
    24481 agcaaccata tagataagac taaaaaagag ttttgactca gattaggccc ttttaaaatt
    24541 tctataacaa gtctatcatt tccttctaac caataccata atcctaaaca aatcaatatc
    24601 caaaaaagaa cataacccca aaagtacttg gtatagatta tctgattcaa cctccacatg
    24661 tgactactta actttcccat ttccaacttt tacactctcc tccagtttct atgaacagaa
    24721 aatacagtca atggaattat gatagatagt aatgtaagcc aataaatcaa tgcatacgga
    24781 ttggaattta ccatatactg aaaaattggc aataatccaa ttatcccatt gtccaactga
    24841 taaatccaga ataaggattc tacaaataaa aaagtaaaca gaaatactaa gctcatgttt
    24901 gattttttaa accaagaaaa actgctaata gtaagtaagg ataaaaagaa atagtatgct
    24961 atataagaga aaaaaaatcc tataaaaaaa ctagcattgt ttgcaatact tataccataa
    25021 aattctctta aaaaatcaac ctcctttatc tccaaagaga agctaaaacc attactaaat
    25081 gcaatcagaa aaatcaataa aaataaagtc gccgtccaaa tccccgtact aagagctgct
    25141 aatttgaaac taaaactggt aaagtgctta attgatttca gacgaatacg acactccaac
    25201 ctattaaaat agttattcat caaataaaaa aagaataata tatatgtgaa cggaaagcaa
    25261 tatactccag tcgtcatatc ttgaagtaaa actaagatcc attctaatac atttggatgg
    25321 attgaatatt ggcgacagcg caataaatat actgtactag ataaaacaca ggatagcagt
    25381 aatataaaat aaaccaatac tgctaagaaa tcttttttat aaaattgaac aaattgtttc
    25441 attatacata gtcctctgaa tgtagaaaaa atgtaccata aacaaccaaa caactaacaa
    25501 ataaaataaa agcaagatgc ccactaacta aggaaagact gatatctttc tgatatccca
    25561 aagctagcgt tgtcacaggt tctaagtaag atagccctaa aatagcccat aaaataccac
    25621 caaccatcat ataggcaact gggatgaaaa tagctcctaa ttttttcttc actagcaaag
    25681 cactagctag tccaaaaata gagaacacag cgccccaaac tccataccag agagtcgtca
    25741 caagactata gagaaactga ttggaatcaa ataattcttt taaggcacca ctataatctc
    25801 caatataaat ttcctgataa ggagtcacta aaagattaat tcctaataat aataaatagg
    25861 ggagaaaaaa gactagaaaa gaagaaataa ttgcagtact acctacaata gctagatacc
    25921 tctttttaga aattcggcac aattgtgctg ttagaaaatg actctcagca tcctctatta
    25981 tctgactaga atagggcagt gtacagataa gtgcagctac taggctaatc ggtgaaaatc
    26041 ctcgaataga agaagcggca aaaaaaatcg ataaaccttc aattttataa ataccattga
    26101 aagcaaggaa atttcctaaa ctcatgcaaa gaagggtcaa aaataaagac atataaaacc
    26161 gaggtgattg aacgactcgt acaagattac aaatgaaaaa ttccatcctt actcctcctt
    26221 ataataaaaa tagggtgtag cattcttttt tcatgctaca cccacaatca accatcttta
    26281 aggcttactc tgacaagtaa gttaataaga atctggactc caagaacctg aagtatgaat
    26341 tcttacataa tttccaaatt gtggcgccat agctaatcta gtaccagaac caatataatt
    26401 gtcaccacct ccattatagt acatgacaat cctagagcca gaccccaatg aatataccgg
    26461 ggtaatatct gacccactat aggcgctacg aatagaggta tttaaccttt taccgccacc
    26521 agtgctgtca ctattattaa ttccagcaga ggcgttttct ttctcaagct cactagttgt
    26581 atccgaaccc caacgcggca acgttaaatc ataatttcca atctgtctag ctaaaactgt
    26641 agggagaaac aaactagatg caattgtaac tacgcaaaaa aggaatatat ttttcttctt
    26701 ttcatgacat cgtcctctta agaagtgata aacaagatag ttgattgatc aatttgatac
    26761 atattacatt ttcattatat caataaaaga aagcgttgtc aattatttta tttaaaatat
    26821 tgtcatattt taaataaaat ggtaaaagag actcggtagc ctcgtctctc tttatcttac
    26881 tgacctaacc ttcttgccaa ttttcttggt cttctttaaa gcgttttaga agatcaaggc
    26941 cctctggcgt gatgtaacct tcttcttggg ctagatggat aagctcgcta tagtttgaaa
    27001 gcgtcacaag tttaacacca gcatctgcaa agttcttatc tgcttttggc aattggtagc
    27061 tgaaaatcgc tacaactcca agtacatctg ctccttctcg cttggctgct gctacagctt
    27121 caagaactga accacccgtt gaaataaggt cttcaaccac taccattttt tgaccttgag
    27181 ctacgcgacc ttcgatttga ttaccagctc cgtggtcttt tggtttgcta cggatgtagg
    27241 caaaaggcaa gtccatctta tcagcaataa tggctccgtg tggaatccct gctgttgcag
    27301 ttcctgcaat cacttctact tcaggaaagg cttctttgat agcttccaca aaaccatttt
    27361 caattagggt acgagtttct ggataggcta gtgtcacacg attatcagtg taaatcggtg
    27421 acttgatacc agatgcccaa gtgaagggtt cctctggttt gaggtaaacg gcttggattt
    27481 tcaagaggtg gctagcgata tctttagcaa gtgtcatggt attctccttt tatttttcta
    27541 atctagttct ttaattccag tcctgtgtcc attcatcctt gatggcatga taagctgcaa
    27601 caggatcctc agcttgggta atgggacgtc ccactacgat atagtcactg ccgatttgat
    27661 aggcatcagc aggtgtcatg actcgttttt gatctccaac tgcaacacca gctggacgaa
    27721 tccctggtgt cagacagata aaatctggat tggtagcctg cttgatgact tgtacttcct
    27781 gagccgagca aacaacacca tccaagccag cttcagctgt cttcttggca tagtgaatca
    27841 cagactcttg cagactggtt tggatatttt gaaactcctg catctgagct tctgacgttg
    27901 atgtgagctg cgttacagcg atcaatttgg cttgactccc aagaccttca cgcgccgcct
    27961 tcatcatctc tacaccacca gccgcatgga cattagtcat atcgacacca agctgagaca
    28021 agaccttcat ggctgacttg actgtattag gaatgtcatg aagtttgaga tccaaaaaga
    28081 cactatgacc caaacctttt aagtaggaca caatctcagg ccccgctgcg taataaagct
    28141 ccatccctac cttgagataa aggctttctt ctgctgggaa aagagctaaa aattccttga
    28201 ccgcctcaaa actaggaaaa tcaagagcaa tgattggacg atgttctcgc ataggtttct
    28261 ccttttacct ttactagtga gagagtctgg ccaacagaag ccacgaaaaa aggaacctgc
    28321 caacagcaag gttccacgaa aaatgggtag tctccaccct ttcaccgtct aaccttagct
    28381 gcctctctgg actgctttaa aggttttcta ttattctatt atttctacta gcacttgtca
    28441 agtaaaaaca tggtcactaa agaactataa gagaaaaggt aaacctagcg acgcgatgag
    28501 cgctgggtcg tttgatttcg attgctctct tcctcttgtt ttttctgttc ttcttcctgt
    28561 tttttctcgg cttccttggc ctcttgtttg gctttttcct cagcctccat aattaattta
    28621 tccgccacag tgtaactgta aattccagct tccatgtcga ccacactcgg ttctgacaat
    28681 tgtggcttaa tcttactgta atatggcagt ttcttactca tttcagatag aggaaccaag
    28741 acttcgtccg aatcattcat ggtcaatcga attaaatcgg atgtcacctt gcttggggct
    28801 aattccacct tttggatagc cgccttgagt tctgggctaa tttgagcaag ttctgagaca
    28861 aaaaccttga tttgttcact atcattaaag agaactgata aataagtttc tggtaaactg
    28921 ttcagactca cagaactagt ctcaagctga ccactggaaa gaataggata atgattttca
    28981 ccagaaatat agtaggccac aatatcatat tccttgacct taatagtgaa cttagttgga
    29041 aattgataga caagttgagc tgattcaacc caatagttag acttaatctg cttttcatat
    29101 tttgccttgt ctagcagaag gttaatcgta taatccgaat cctgaatgcc tgaagcctgt
    29161 cgaatatcat cagctgtagt ttgcaccgtt ccctcaacac gaatatcttt catggtcgca
    29221 taaggactga gcaagtaggc agagacaatc aataaaagca gacttggaaa taaaatcgtg
    29281 aaggctcgca agatatggat accaggaatc tttgctttgg ctggtttttc ctttgtagcc
    29341 tttttagaaa gctttttatc ctgttcctcc ttctctttag actctggttc ttctttctct
    29401 tctttctctt tgtcagcctc tgaggatgct actttttctt cagactcttc cttagctgat
    29461 tctgaatctt cctggtctgt ttcactctcc tggtcctgtt tgtcctctga cttctcagat
    29521 tcttctccca ttcgagcttg tctttccttt tccttctcct cagctagagc cgcctcttct
    29581 tcagccttct tttttagata ttcttggttt cgtttctgcc attctgataa ctctttcaat
    29641 tcttcgagga tttctttgtc ctcatttttc ttatcttttg acatttactt tccttatgat
    29701 aaatcttttt tcaacaattg ataaaaatct gctagagatt tcaattcctt agaagccttc
    29761 atcttagctt ggtaatcttc cttgtgactt agtaagtgag aaagcttctc ttccaaacta
    29821 tccaaggtca aatcgctttc ttgaaggtct tctgcatagc ctttttttac aaagtaagct
    29881 gcattttcaa gctggtcacc acgactagct tcacgaccaa gcggcacaat gacatgcaat
    29941 tttgctatcg ccaagagctc aaaaatcgta ttggcaccac ctcgtgtcac aacaatatca
    30001 gccaattcca tcaagggttg atagagatcg gtcacatagt caacacgaaa aagattttgg
    30061 ctcaactcat tcaggctaga atctccagtt agattgataa tattgtagcg ctctgttagt
    30121 tctttcttat ggtctgtcac caattggtta aagacacgag cacctgcaga accgccaaca
    30181 aacaatacag tcggcaattt atgattaaag tggctttgaa tatccaccaa ttcatctggt
    30241 tctggatttt tttgatctga aaccttggtc actgctccca catgctcaac cttagacaaa
    30301 ctcgaagctt gctcaaaggt tgaatacatc ttagtcgcaa atttataggc gattttattg
    30361 gccaagccca tagacaggtc agattcgtga ataaagacag gcactcctga cacacgcgca
    30421 gcgataacag gcggtactga gacaaagccc ccctttgaaa aaagggtctg tggacgaagt
    30481 cgcaacatga taaagagcga ttggacgatt ccccagcaaa ctttgaagac gtccagcata
    30541 ttttgccaag agaaatagcg acgcaatttt ccagtcgcaa tagaatggaa ggtgacatcc
    30601 aaacctgact taaggatttc ttggtgttcg ataccacgct tgtccccgat atagtggact
    30661 tcccaaccat cttcgatgaa cttgggcatt aacaaaagat tgagggtaac gtgtccaacc
    30721 gtccccccac ctgtaaagac aatttttttc atattattct tttaactccg ctactgtgtc
    30781 gataaagagg tcgccacgta cttcaaagtt agcatacata tcccagctgg cattggcagg
    30841 actaagaaga accacatctc cttgagtcgc aagctcatag gccttgcggg tcgcatctgc
    30901 aatatctgtc gcctccacat aagcgacacc agccttgtct gctgcccgtt tgacacgttc
    30961 tgcagattga cccaggatga ccatcttctt gagtccagta atgtctggca ccaattcgtc
    31021 aaactcattg ccacggtcca aaccacctgc aatcaagacg accttgctgt tatcaaatcc
    31081 tgacaaggct ttttgagtag ccaagatatt agttgattta ctgtcgttat agaatttaac
    31141 acccttgatg tcatccacaa actggagacg gtgtttgaca ccaccgaagg ctgaaagagt
    31201 ttccttgatg gtttgattgt ccacaccacg aagcttggct acagcaatag tcgcaagggc
    31261 attttccaca ttgtggctac ctggaacacc gatttcattc gctgccatga ctacttcacc
    31321 acggaagtag agttgaccat cttccagata agctccatca accttttcaa gtgttgaaaa
    31381 tggtacaaca gtggcttctg tcttggaagt caagtctttt gccaagtctt gattaaagtt
    31441 caagacaagg aaatcagctg ctgtcatctt gttctggata ttccacttgg ctgctacata
    31501 ttccgaaaat gacccatggt agtcgatatg agttggcatg aggttggtaa taaccgcaat
    31561 ctctggatgg aattcttgaa cacccatgag ttggaaagaa gaaagttcca taacaagcgt
    31621 gtccttatct gatgctattt gagcaacctg actagctgga tagccgatat tccctgataa
    31681 aagaccatgt tgcccagcag cagtcaaaac ttccccaatc atagtcgttg tggttgtctt
    31741 accgttcgat cctgtgatac caataatcgg tgcttctgaa atcaaataag ccaattccac
    31801 ctcagtcaag actggaattc ccttggccaa agccttttca atcatgggat tgttgtaggg
    31861 gatacctgga tttttcacca taagggcaaa ctcttcatcc aagagttcca aaggatggcc
    31921 acctgtaatg accttgatcc cttcttccag caaactttgg gcagctggat tgtcctcgaa
    31981 aggtttccca tcatttactg tcacaatggc acctagcttg tccaacaaac gagctgcaga
    32041 ttcaccagac ttggccaaac ctaaaacaag gactttctta tttttaaatt gatctattac
    32101 tttcatgtct cgaactccat ttctactcct actattttac catttttatg gaaataaaaa
    32161 agccacaaag tgtgtttgtg actctttctt ctaactgaat cttaccatat catctatgtg
    32221 ataaatcggt aactcgaatg acctgatcca cttgttccca aatcagagga ttgtgggtcg
    32281 caataataat ggtccgattc ggatttttta aagattctag gatggaaagt aattcctcag
    32341 agtttttggg gtctaaggaa gtggttggtt catctgcgag gatcaaaggt ggatccttta
    32401 aaattatctt cgctaatgca acacgttgtg cttctcctcc tgataactca aatataggtt
    32461 gcttcaaatc caaataagag aggtttacac agtttagagc ttgtttcatc aaagagattt
    32521 tctctttttc cttcaacttt ttaccaacta aacccagatt gagattctct ttgacggttt
    32581 ggctttcaat taagccaaaa tcttgaaata agtatcccaa gtaatctcta aagaaaacag
    32641 aaggcttgat gtccttaaga gaagtaccat catagatgat ttgtcctttg tcatatggct
    32701 ctaatcgtcc aatcatattc aagaatgttg tcttaccaca gccacttgta ccgattaagg
    32761 cataaatttt cccaccttca aaatgaagat ttgtatctga aaatagctga cggcttccaa
    32821 attttttaga tatattcttt agttcaatca tcctattttc ctttcataat tgtcatagaa
    32881 acacgagatt ctttctgcgc ttgacggtaa agcgtcagaa ctgcactagc tagaaagact
    32941 aataaagtga gcaagccaat caccaagtct cgactgctta aaataaagag actagcacca
    33001 aatacaaaac tggcaaattg actaaccata tactgagcat gtgtttcaaa aaatcgtaaa
    33061 cctgaaattc gtttaatcaa aatatctcgg cggaattgct cgaaatatag aagattgaca
    33121 gaataaaata gtaacaagga actagctatc cccacaatag ctcctaagat taaagttgct
    33181 gtttcagttt gaacttcatt ataacgagtt agataaacac ttcttccttc tttaagatag
    33241 gatacttgct cataaattcc agctttcttc aagagttcta gcccactctc atatcctttg
    33301 ataaagagtt gttttccagc attgatagac caactagata aggatataaa actatcacct
    33361 gtagaagtcg gcgtgaatac cactaaaatc ggagcagtca aatactgagt agatacggga
    33421 ttctcaccgt tattataaac aaaccgcttt tctcccattg aaagataact aacgtgcgct
    33481 ttcatctcat aatccaaagg agcacttgcc tcctcaccag attttccata ataactcaat
    33541 ctttcttcaa aaactttctt aagttctgct tctcgagagc gcaaatgttc tgggagcaag
    33601 aggataaact cacctttttg gagatgggct aacttctgtt tggtctcagc atctaccacg
    33661 accttttcct tgtccaaata actgggacta acatagagcg tattagcatc tggactatag
    33721 gtatccagtg tctctccctg ttcatttttt ccttgtggat tggcaaaatg gagcagatta
    33781 tcctttacat aaagagcttg ttcttcttcg attgcttcct tggcaaaggc ataccacttg
    33841 ctctgatttt ctgtatcttt tcctctatca cctaagccaa aagaaatttg ataatagtct
    33901 gctctatcct gccatgcttg ttttgaaatt tcaagttctt tcaatcgttg gtaagacatc
    33961 aaacctgtct taacagcgta gcctactgta aagacagcaa ccaactgaca caatagggtt
    34021 aaaatcatca ggcgtttaag gggtaatctc cccttaataa cgggaactaa tgctttgtaa
    34081 ctcaaactca ttagataaag aagcattagt aaaattgaaa tcgccaataa aaacaacaga
    34141 tagaaactaa tcccaaaacc ataggtggct aacaagatag gataaaacaa accttgacta
    34201 aaaagaacga ctcccccacc taggaaggaa aggagggctg atagaaggag ccatttgata
    34261 tcagtagata aagaatgccc catgatggat aagagagtct gaccagaaaa gagttttata
    34321 cctgctgctc tcatttcctt aatccgagtg ataatcacta aagcaaagaa agataagcca
    34381 aatattgcta aactaattaa aataagggga tttagtaata ttcgaaaagc aagaaaatag
    34441 ggcggtatct ttcggtcagc acttgcttta taacccaaat ctcctaattt atcggcaagc
    34501 ttttctttcg tcaaggagcc tgacaaaagg agataactat ttagcggatc actacgttca
    34561 cgactttctt ggctagcttc ttggaattct tttggtaaag ttccctgacc ataagttgca
    34621 taagtaaagt gagtcgtccc atccttactc ggctctacaa ttcttctagc tattaaactc
    34681 tgttctgagt ttgcaaaatt ctccaattcc tgttcaaata cctcacgcgt cggttcctga
    34741 gtatcttttt tgacacgaag taaagaaacg gaatcatagc ttgcatataa atattgtggc
    34801 gcacgtaaga caataatcca agcaaggaag aagctgagaa aaaagttgat aataatatga
    34861 atagtttctt catagtagac tccttgtaaa caaaattccc cctgtaattt cttacaaggg
    34921 gaacgattta aatcaatgaa cgattagtca taatcacagt aaaatgctac ttgttctccc
    34981 catttagtcc aaatccatgc ataggaggtt tttccagcag aagcttctcc tttatctgaa
    35041 tgactattcc atctacttac aagagaagaa taatgatatt ttttaccatg atagtaattt
    35101 gaaaaagccc aaccacctcc tgaaccttct ccatacgtcc atactcctcc atctggatat
    35161 tgtacagcag ctgatgcagc tcccaataat gtaaaacttg aaataagagc tagagcaagt
    35221 aatctatgtt ttttcgtttt cattttattt tttctttcaa aaaaagcaca ccttgagcaa
    35281 caatgcaaca aaataaaccc tcctctctct tttgttgaaa ccgctttctt atgtgataaa
    35341 aatatcattt ttattatttg ttgtcaagga aaaaatcgaa ttttttagat attttactac
    35401 attgcctcta tgaataatat tatatagtag ttttatttta aaataatatg caaccagtac
    35461 taaccaaata taaaatagat gccattaacg aattttattc aagtttttcc cattcatact
    35521 atccaagcaa aagagatgat gttatagtac aaaacaattc aaactattgt aaaattccta
    35581 gcaaaaaaga gagccaaaac tctctttttt atcttctttt actttttttg actggcatga
    35641 gtgtaatgtc tctaacacta aagtaagcta ggatcaacat ggctattgct aggaatattt
    35701 ctgttggtaa ttgaaaaatt ttcagaaaag atagaaccaa taaaatcaag agtgccacta
    35761 aaatacatac catagcgacg atattgactg tccctttaat gctttctggt gtcgcaaata
    35821 catagagtag gagcagtaaa attcctagga ctaaatagac catctttctc tctttctagc
    35881 tcttattcag ctgatttttt cttcttgtta gctttctcac gctctgcttt gttaaggatt
    35941 tgtttacgca aacggataga ctcaggcgtt acttccatgt actcatcgtc gttcaagaac
    36001 tcaagagact cttcaagtgt caagatacga ggcgtcttga taacagctgt ttggtcctta
    36061 gtagctgaac gaacgttggt catttgtttt gccttcgtga tgttaactgt caagtcattt
    36121 tcacgagagt tttcaccgat gatcattcct tcataaacct cagtacctgg gttgacaaag
    36181 atcgtaccac gttcttcgat agacatgatt gagtaagttg tagccttacc agcatcgata
    36241 gaaacaaggg caccacggtg acgtccacca atttcccctg gaatcaatgg caagtattgg
    36301 tcgaaggtat ggttcatgat accgtaacca cgagtcattg acaagaactc agttgagtat
    36361 ccaatcaaac cacgcgctgg aacaaggaag accaaacgag tttgaccatt accagttgaa
    36421 atcatatcca acatttcacc tttacgttca gaaaggcttt ggataacaga cccttggtat
    36481 tcttctggag tgtcgatttg tacacgttca aatggttcac atttaacacc gtcgatttct
    36541 tttacgataa cttctggacg agatacttga agttcatagc cctcacgacg cattgtttcg
    36601 ataaggattg acaagtgcaa ttctccacgt cctgaaacag tccatttatc tggtgaatca
    36661 gttgggtcaa cacgaaggga aacgtctgtt tgcaattctg cctgcaagcg ttcttccacc
    36721 ttacgagaag ttacccattt accttcttta ccagcaaatg gtgagttgtt gaccaagaaa
    36781 gtcatttgaa gagttggctc atcgatgtgt aggattggaa gagcttctac tgcatctgtc
    36841 ggagtgatgg tttcaccgac aaagatgtct tccatacctg aaacggcaat caagtcaccc
    36901 gctttggctt cttggatttc acgacgttcc aaaccaaaga aaccgaagag ttttgtaaca
    36961 cggaagtttt tagttgtacc gtcaagttta gaaagggtaa cttggtcccc aaccttaact
    37021 gtaccacgga agacacgacc gataccgata cgtccaacga agtcattgta gtccaaaagt
    37081 gacacttgga actgcaaagg ctcatctgag ttatctactg gagctgggat atggtcgata
    37141 atcgtgtcaa agattggtgc catagtcgct tcttggtcag ctggatcatc tgacaatgaa
    37201 gaagttccgt tgatcgctga agcataaacc actgggaaat caagctggtc gtcatctgca
    37261 ccaagctcga tgaaaagttc caagacttca tccactactt ctgctggacg agctgatggc
    37321 ttatcgattt tgttaacaac cacgattggg acaaggtctt gttccaaggc ttttttcaat
    37381 acgaaacgag tttgtggcat ggttccttca taggcatcta cgaccaagac aacaccgtca
    37441 accattttca tgatacgctc aacttctcca ccaaagtccg cgtgtcctgg tgtgtccata
    37501 atgttgatac gagttccgtt gtaagcaacg gcagtgtttt tagcaaggat ggtaatccca
    37561 cgctcttttt cgatatcgtt tgagtccata gcacgctctg ccaattcagt acgtgcatca
    37621 agcgtttctg attgtttcaa taattcgtca accagggttg ttttaccgtg gtcaacgtgg
    37681 gcgataatcg caatgttacg gatatcttct cttaattttg tcatgatttc ctctataata
    37741 ttcaaaattt attttctaac tgaacgatta taccataatt tcaaataaat aacataactc
    37801 aagcaagtgt aaatgttttc actccgcttt tcttttcacg tcaagccttt tcaaagcaag
    37861 cgacttatga taagataggc acagtatgcg tttagataat ttattagccc aagaaaaagt
    37921 tagccgaaag gccatgaagc aagcactcct cagaggggaa attctagtcg atggttgccc
    37981 agcccgctcc ctagctcaaa atatcgatac aggactacaa gaactccttt ttcaggatcg
    38041 aatcattcaa ggctatgaac acacctatct tatgcttcat aaacctgctg gtgtcgttac
    38101 agccaacaaa gacaaggaac ttccgaccgt catggacttg cttccatctg acatccagtc
    38161 tgacaagctc tatgccgtcg gccgactgga ccgagataca acaggactcc ttctcttgac
    38221 cgataacggt cccttgggct tccaactcct ccatccccaa tatcatgtcg ataagactta
    38281 tcaagttgag gttaatggac ttctaacacc tgaccatatc caaacctttc aaaaaggaat
    38341 tgtcttttta gatggcacta tctgtaaacc tgcaagacta gagattctat cagcaagtcc
    38401 ttccctcagt caagcctcta tcaccatttc agaaggaaaa tttcatcaaa tcaagaaaat
    38461 gttcctctcg gttggtgtta aggtgactaa cctcaagaga atccaatttg gggacttcac
    38521 attgaaccca gatttagcag aaggtaacta ccaccctttg aaccaaaaag agttacaaat
    38581 cattaaaaac tatttagaga tgagtcgata aaacaaaaaa agctttaaaa ctaaagcttt
    38641 tttcttttat ttaccgaaaa attaaggcga ttgctacaat ccagttaact acagaaatca
    38701 caattcctaa gatattaaga atcttttcta ttttatagtc taattgtgac tctttttggt
    38761 atgaaatagc caagaccaat cctatgatac ccaaaatcag gcctacaatt ggaaataaca
    38821 aaccaagaat aatcgacaag atacccacaa aaagtggatt tttcttcttt tctttcatgt
    38881 tctaagaact ctttaaattt tatacaaatt aattatacta taaaacaata gcttcattct
    38941 atcattcgac taatttggaa ataaggttag ctagtcttca ctttcccttt ccaagaatcc
    39001 aagccataag aaaggatata aatctcagaa aaaccttgtt ttttcaagta aagagctgca
    39061 tttgtaactc gttgcgcacg ttggttttcg tagagaagga caggtttatc tttacgaagg
    39121 gctgcaagac tagttttcaa ctgacttgaa ggaatattgc gtgcaccaag gatatgtttt
    39181 ctgtggaatt ctgctgggtc gcgcaaatca atcaattgac ccgtacgaat caaggcttca
    39241 aactcctcat tgtccacaat tttagccgca cggcgaatac gaagatagtt aaagcccatc
    39301 cacgccaaca ttgctagtat aagtgcccac aaaatccaag taaccattag ttcttttctc
    39361 catttttctc aatataatcc aattctacct tgtgctctct gcgaagaact gcttctgcct
    39421 ctagatagtc taatttatcc atcaaccctg catcgtaaat ccgagatagt tccaacttca
    39481 tcagttcaat atcatataag cgttttccca tgtaaacaat aataccaaat cgtttgagga
    39541 attgctgcac atcatagaat gttttcataa gactcattct agcaaaattt tgtgtttttt
    39601 tcaagaagag actcacacaa tgctccttat tttcctatct tctttagcga ttctaaggca
    39661 agtatggtac aataaaaaca tgagaattca acaattacat tatattatca aaatcgtcga
    39721 aactggctcc atgaatgagg cagccaagca actctttatc actcagccaa gtctctccaa
    39781 tgcagtgcga gatttggaaa atgaaatggg cattgagatc tttatccgca atcccaaggg
    39841 aatcaccttg acccgtgatg ggatggagtt tctctcttat gcccgtcagg ttgtcgagca
    39901 gacccagctt ctggaggaac gctataaaaa tcctgtcgcc caccgcgaac tctttagcgt
    39961 ttcgtctcaa cactatgcct ttgtggtcaa tgcctttgtc tctttgctca agaaaagcga
    40021 tatggagaaa tacgaactct tccttcgtga aactcggact tgggagatta tcgacgacgt
    40081 caagaacttc cgcagtgagg tcggggtcct cttcttaaac agttacaacc gtgatgtttt
    40141 aaccaagatg ctggatgaca atcacctgct agcccaccat ctcttcacag cgcaaccgca
    40201 tatctttgtc agcaagacca accctctggc aaagaaagac aaggtgaaac tgtctgattt
    40261 ggagaatttc ccttacctca gctatgacca agggacgcac aactccttct acttttcaga
    40321 agagattctt tctcaggaac accacaagaa atccattgtg gtcagtgacc gtgccaccct
    40381 ctttaatctc ttgattggtt tggatggtta taccattgcg acagggattt tgaacagcaa
    40441 cctaaacgga gacaatatcg tttctatccc actggatatt gatgacccga ttgagctggt
    40501 ctatatccag catgagaaaa ccagcctatc taagatgggc gaacgcttta tcgactatct
    40561 actagaagaa gttcagtttg atagttgaga aatgataaga accaatatgt aggctagcaa
    40621 caacctgcac attggttctt tttacttata attaaaagtt tcccctgcca acttatcagc
    40681 tagcttggga aagagagtat aaaacttatg ggctaggttc aacaaaatcg ggagattgag
    40741 ttctcgttta tttttgccta taatcttgac aatcttttta gccactgcat ctgcctctaa
    40801 gaggaagcgg tcaaccgatt taagataagt tccatctggg tcagcttggt caaaaaatcc
    40861 tgttcggatt ggacctggat tgactgttgt cacatagact ccatagggca taagttcgag
    40921 tcgcagagca tttgaaaaac caatagccgc aaacttggtc gctgagtaaa gactagactt
    40981 gccagtagct attagacctg ccatgctgac gatgttgatg atatgccctt tgctgctttc
    41041 cttcatacga gccgcaaggt gacgagacag attcatcagg gcaaaggtat tgacctcaaa
    41101 catctggtga atatctttat cagcaatctg gtcaaatccc tcaaaaatcc cgtaaccagc
    41161 gttgttaatc aagacatcaa tcttgccata gcggagataa agatcagtta ccagagcttc
    41221 tagggctgaa tcgtcggtaa tatcaatttc aatcaattct gcatgggaat aatttccgta
    41281 gagttgggct aatttttcct tatttctacc aagcaagatg agttggtcat tgggcaggag
    41341 tttgaccatt tcttgagcta gaccaccgct agctccggta atgagaatag taggcatact
    41401 tatcctttct gtgactgcta gatttccact tcttccaagt ctttgaccac atggacattt
    41461 tcaaaaattg tggcagcgtc cttcttgagt ttgcttatat cttttgagag gaaacgggca
    41521 ctgatatggt tgagtaggag gcgtttggca cctgcttcta ccgctacttg tgcagcttgc
    41581 atattagttg agtgaccatg gttacgagca attttttcat cacccttgcc ataagtggac
    41641 tcatgaacta ggacatctgc attgacagcc agacgcacac tggcatccgt ttttcgagtg
    41701 tctcctaaaa tagtgataat cttacctgga cgtggcgctg agatatagtc tgctgccttg
    41761 atttcagttc cgtcttccaa aacaagatcc tggccgtttt tgattttacc aaaaagcggg
    41821 ccgaacggaa caccagcagc cttgagtttt tcagcatcca gcgtcccttc tagatccttt
    41881 tgcatgacac gatagccaac acagaaaata gtgtggtcca gctcctctgc atacacagtg
    41941 aatttatcgg tttcaagaat tttacccaga gaatcttggt caaactcatg gaaatgaatg
    42001 cggtagggca gacgagaacc tgacacacga aggctggtta agacaaatga cttgattcct
    42061 tgaggtccgt agatttccaa atctgtctgc tcttcattgg cctgaaaggc acggctagaa
    42121 aggaaacctg gcaaaccaaa aatgtggtct ccatgcagat gggtaataaa gattttgctg
    42181 accttacgtg gtcgaattgt ggtttccaga atgcgatttt gcgtaccttc tccacagtca
    42241 aagagccaaa cttcgttaat ctcgtccaaa agtttcaggg cgagacttga aacgttgcgg
    42301 gctttagagg gctgaccagc ccccgttcct aaaaattgaa tatccattcg atactttcta
    42361 attaatcaat atataacatg gctgtgcggt tttccgatcg gaaatagcgt ttgccagaaa
    42421 aagcagcagc ttcttgcaat aaatcctctt ggctgtagcc tttgagacgt tttcgaccat
    42481 cagccaatct ttccaaatca gtcaaagctg tgagactttc taggctgaca acttcctcgt
    42541 ccttgacagg tttcatgtaa atcttaccag actcttcaaa gactaattga tgggagaaaa
    42601 tttgcgcaat ttcaaagagc aagtcatccg agattttctc ctcattttca gagaaaatcc
    42661 gaccaaggcc gtcactctca taacaaaaac caaaggattt accagacaga ttaagccgaa
    42721 taaaaggctt attttctagg gtgaaacttg gctcagtatt gtaaagattc agttcctgac
    42781 tgagttctgc aaaataatcc gtcgcagcct gaggactttt tttctgatag agttctgcaa
    42841 agtaggcatt aacaacactt ggcggaggtg taataagtgt taactgctcc tgctctgttt
    42901 taccagctag aagctgatcc agatagacct tgtccagact tgtataacct ccatacttta
    42961 gagccaaagt tttaatatca gtcataaaat tcttctaacc tccatttatt tttctcggaa
    43021 atgtagcctg taatcacttc gccgtcttcc tgataatcac gttcttccag aattgcaaca
    43081 ctctctaaat catgaatctt gtaggacttt gaaaaaggca ctcgcagggt aaatgcttca
    43141 aaaatttcct taatcttatc tagcaataat gcttgcaagt tttcacgact gtcctcagac
    43201 ttggcagaaa tgagggtata tggcgtttgg gtaggcgtga aatcctccac caaatccgct
    43261 ttattataaa gcgtcaagtg aggaatatct tccatgtcca ggtctttcat gatggagaga
    43321 accgtttttt catgctcctc gtggtaagga ttgctagcat cgataacatg aaccagaagg
    43381 tccacatgct tgctttcttc caaggttgac ttgaaactgg acaccaactc tgtcggcaaa
    43441 tcttggataa agccaacggt atctgtcaaa gttacttgga gattgcctcc cagatgaata
    43501 ctcttggttg tcgcatccag agtcgcaaag agctcatctg cttcatactg ggtcttactg
    43561 gtcaagatgt tcatgatagt tgatttccca gcattagtat aaccaatcaa accaatctta
    43621 aaagtgctag actccaaacg tttttctctg acagtcgcac gatttttctc aaccaccttg
    43681 agctggcgct cgatatccgt gatttgattg cgaacgctac gacggttcag ctccagttgg
    43741 ctttcaccag gaccacggga accaattccc cctgcctgac ggctgagcat aatcccctga
    43801 ccaaccaagc gaggcaagag gtatttgagt tgggctaggt ggacttggag cttcccttca
    43861 tggcttcgag cccgcatggc aaagatatcc aaaatcaact gcatacggtc aatgacctta
    43921 acaccgagaa cttcctctag attgacattc tgccttgggg tcagacggtt gttgacgatg
    43981 acagtagtga tttcttctgc atccaccata agcgcaatct cttccaactt accagagccg
    44041 acgaaggtct tggaatcata tttttcacgt ttttgtctgt agctatctac aacgactgcc
    44101 cctgccgttt tcgctaaact agccaattct tccatggaga ggtcaaaact gtccataccc
    44161 tgcaattcca caccaatcag caggactcgc tcctcttttt tctccgtttc aatcatctaa
    44221 aaactcctct atctggctta aaatgcggtc ttgtacacca gattctccaa tctgataaaa
    44281 ggtgacctgc atgcgattac ggaaccaggt cagctgacgc ttggcaaaac gacgggtcgc
    44341 ctgtttaaga ctctcacgag cttcctcaaa ggtctgctct ccacggaaat aaggaaagag
    44401 ttccttatag ccaattcctt tagcagcctg tacattaggg gaatggtcaa acagccactt
    44461 ggcctcatcc aaaagcccag cctcaaacat caaatccact cggtggttga tacgctcata
    44521 aagttgacta cgttcatcat ccaagcagat aatcagcggt tcatacaaaa tctcttgatt
    44581 ttccaaatcc tgaccaaaat gggcaatttc taaggcacgc atagcacgac gacgattaaa
    44641 ctggggaatc tcaaggcctg cttgctccac caaatgggct aattcctcat ctgaatatgg
    44701 ctccaaacta gctcgataag ctaaaatctc ctcatgagga gtctccccac ctaggtggta
    44761 accttctagc aagctctgga tataaagtcc agtcccaccg gcgataatgg ctagcttgcc
    44821 acggctgtga atatcctcaa tagtcatctt agcttctgaa acaaaatcaa aagccgagta
    44881 agactcggtt atctctctaa catcgattaa atgatgagga acagctgcct gctcttctgg
    44941 actagccttg gccgtcccaa tatcaagtcc tcgatagact tgttggctat ctccactaac
    45001 cacttcgcca ttaaagcact ttgcaacttc aatagctaga gccgtctttc caacagcagt
    45061 cggtccaaca atcacaatta tttttgtttt catctttttt ccttgaaaaa ttcccatttt
    45121 ttcgttacta ttattataac acaaaaaggt cagtcagaaa aatgtgacct cttgaggagg
    45181 ctggctgatt gagaatataa aggaggaaga ctcatggcta aaggattcgc taaaggtctt
    45241 gtaacaggtg tcgcaggaac tgtcgctgcc gttgcaggtg cagtatacgc atttaaaaag
    45301 aaagtaatcg aaccagaaga gcaaaaagca gctttcatcg aagaaaaccg taaaaaagca
    45361 gctcgtcgcc gcgtatcacg ttaagaaaca aaagaagttg ggattattct caacttcttt
    45421 tttctattct tttaaatagc taggtcaaac ttcaactgtg gcttaacagg gtcataatcc
    45481 accaactcaa aatcttctgc tttgatatca aagaaattag tcccatcagg aacatttaaa
    45541 accaagcgtg gttggcagtt tgacggctcc cgacggagca attcctgagc ttgttcaaat
    45601 tgattatcat agatatggag gttgttgatg aagtagaaga acttcccaac cttccagcca
    45661 aaatgtttgg caatcatcat ctgcaaagcc acatactgca tagcgttgat gtggtgggcc
    45721 accagcatat cattggagcg ctgggtcaag gtcgcatcca gatagatttc cccatcaaca
    45781 cgccggacat caaacatggt ctgaaaggcg cacgggagca gcccatctgt ttcttcgaaa
    45841 gcttggtaat cccagagcga aataatattg cggcggttcc aaggattggt ttccaactgt
    45901 ttgagaagct tattgataat gtcgtgtttc ttaacaacgg caccatagcg ctcaccaatg
    45961 gttcccgtgt ctccaacttc ccagtcattc cagtagtgaa cattgtactt gtcattaagc
    46021 acttctaagc tatttgactg gtcttggtaa atccagagaa cttctttgat ggcggatttg
    46081 attgcaatgg gacgcaaggt tgtgatagga aattctcctt tagataagtc gtactcggaa
    46141 aaggcaccag ttacatactt ggaattagca acagtcccat ccttgtactt aggacgagcc
    46201 tgctctgaga aaacaccttc ctttagaatg cgttcaatat tctctttaaa aatcgtatct
    46261 gcttttgtca tttcgtttca cctcattcat tgtcctaact agtatagcat aaaaaataaa
    46321 agaggaacat tactaactct aggttagcat tttcctctct cattatctta ttgcaataca
    46381 agtgatgctg ctccgataac tccagcgtca tttcctagag ttgcaagagc taatttagta
    46441 gatgtgcgta cttgtgggaa actattttca tcgtaaactt tttgaacacc ttgtagaagg
    46501 aattctcccg cagctgacac accaccaccg atgacgattg ttgatgggtt taggattgaa
    46561 ccaatgttag cacaagcgat tcccaagtaa cgtgagaagt tacggtaaac aatcaaagca
    46621 aggtcgtctc cttcttttgc gagatcaaag acagtcttag cagttacttc ttctccgtta
    46681 tcaatcaagc gtttcaaggc tgcatcgcct tcgtattcat cggcatagcg acgagtcaag
    46741 ttgacaatcc ctgttgctga agcaactgtc tcaaggcagc cttttttacc acaagtacat
    46801 gagattggtt ggtcaaagtc aacagtgata tgaccaagtt cacctgctgc accagcaaca
    46861 ccatgaagca atttgccttc tgcgacaata ccaccaccaa caccagtacc gagtgtcata
    46921 aagacaacgt ctggttggtt atctccagca cccatccagc gctcaccaag agctgctacg
    46981 ttggcatcat tatcgatgaa aaatggaatg cccaaagctt tttcaatctt ttgtttgatt
    47041 ggttgaaggg ttttccagtt caagttgtag gcaccgataa cagtcccttt ttcacggtca
    47101 accacacctg gtgatcccat tccaatacct tggaagtccg ctgctgccaa tccaagcaag
    47161 tccaaacgat gttgaataga ctcaatcata tcatcaacga tatgacttcc ctcatccaaa
    47221 atgttggtct tgattgacca ttttccttgg atttctcctg ctgttgttaa gattgcaaat
    47281 ttgatagaag ttccaccaag gtcaatccca ataatctttt gactcatcat attctccttt
    47341 ttcattgtgt agtaattgaa aatgcttaca gtactagtat atcaaaatcc attcacttat
    47401 gcaaaggttt gcgtaaatga attataagga attttttcgc ctaccagtat ctgttaacca
    47461 tctaaatgat caatggcata ttgagctgca tcatttgaaa atttatcaaa atcagaagtt
    47521 aattgtctat acatacgttt ttttgacatg tggaataacg aattataact ttttgccttt
    47581 cctaaagcag cagaatattc actattgcta tcattactag aagaagctgt acttgcttga
    47641 ccttccttcc aaactccgtc agcgccaaca taataacgtc caccatcaac ccattcattg
    47701 acagccattt taccatccga ttttagatag taatttcctt gccatgtact gtaagcataa
    47761 gaaccatctg atgtcaaata ataccaagct tgataggtgg catcataaac ccattcacct
    47821 ttagccattt taccatctga tttcaaatag tagtttcctt gccatgcatt gcgagcatat
    47881 gaaccatctg atttcaagta ataccatgct tggtaagaag aatcataaac ccactcacct
    47941 tgtgccattt taccgtttga tttaaggtaa taagctcctt gccatgtact gtaagcataa
    48001 gaaccatctg atgtcaaata ataccaagct tgataagaag agtcataaat ccattcactc
    48061 tgtgccattt taccatcagc tttcaggtaa tagtttccct gccatgcatt ttcactagat
    48121 ttccatttcc atcaaaatag taccaagaac cgtcctgctt aacccaacca cttgctgtgg
    48181 atgaagttgt atcagtttga gttgtagccg cttgttttgc tttaaaagca cccttaggag
    48241 catttttcaa ttcgcaagcc acaccatcat gatcgcggtc taacttggca gaataaccag
    48301 gttctccctc atgaagatcc gaatatccat tagcccaagc ttccttacaa ctcgaaaaat
    48361 gaatgttttc ctctgctaac acaggttgtg aaaacaaggc taaaattggc aacgtcacca
    48421 gactcatttt taaaaataga cgtttattca tttctttctc ccataattat gatatcgatt
    48481 tcaatattat tttatcaaac ttatttcagc aattcaagga aacttctggt cttttctaca
    48541 aactcctttg gttttgcctt attcaagaca tgagggccat ctgggataat ctgaaattgg
    48601 gattctgata ttagtttatg aagacttctc atagaactaa gattcggttt atctttgata
    48661 ccacaaatta gtaaggttgg ataagggcaa gttcctgcta tatccgttaa atcaagtgtc
    48721 ttcaactcct cagaaactcc gaccataaga gccttgtctg ctccctgttt ttcaaatact
    48781 cttttgggaa gtagtttaaa atcagcaact gaagataaaa taggatattc cctgctaatt
    48841 taagcgggca tcctgacaga atcaaagctc gaagatttgg taaatcgtaa ctggaaagtt
    48901 ctagtgccag ggcagcacct aaggacaatc caatcaaaac aaaaggttct gtctcttgag
    48961 ctaggtgctg ataaactcgc tccttagctt gttgatagtt actaactcca gaaggaaata
    49021 actcgatagc ctcagaagga taatctgtca gtagattccg aacttctttc caagactctg
    49081 ctgactgccc taacccatgc aaaaatatca gtttcatcta gttctcctca aggcttagtt
    49141 catacaagcc tctcactgca ttacagccgt aaatagcttc tgcttgggct aaatctgcca
    49201 aggtcaagac tttctcttct acctgtcctg tttctagcaa atactgacgg taaattcctg
    49261 gcaagattcc aagtcggata ggcggtgtgt agagttttcc agcgattttc agaaccaaat
    49321 ttcctataga ggtttcaagc agttttcctg acttattgtg gtaaatcttc tcttgttctc
    49381 ctaggctcaa atgcggtcgg tgagtggttt taaagtaggt aaaggattga ttcaaagcag
    49441 cttcctgaag gcagacttgg gcctgacaaa agcttgtact gagaggggtt aatacttgac
    49501 gattgacttc tatctctcca gatttgctaa ggctgattcg caagcggtaa tcttgattag
    49561 cttcacaatc ctgacactct tcctcaatct tgtgtcccaa gtcttctgca tcaaaaggaa
    49621 aggcaaaata acgactagct tttctcagtc tttccagatg ttgatcttca aacagcaggt
    49681 tcttctggct gatttcccct gtcgtaatca gttggaagcg ggcttgttta cgataaagaa
    49741 ctgctgcctt ttgatgaacc tctcggtatt cagattccca tgtgctatcc caagtaatcc
    49801 ctccgccaac tccataaatg gcttgacctt tgtgaagttg aatggtacga atggccacat
    49861 taaaaatccg tcgtccattt ggaagcaaga gaccaatcgt tccacagtag actccacgcg
    49921 gttgaggctc caagtccttg ataatctcca ttgtcgcaat tttcggtgca cccgttatgg
    49981 aaccacaagg aaagagtgag cggaagattt caacaaggtc cacatcctct cgcaactgac
    50041 tcttgatggt cgaagtcatc tgccaaacag ttgaatactg ctctacctgg cacagacgct
    50101 ccacgtgctc gctcccaact tcagaaatac ggttcatatc attgcgcaag aggtccacaa
    50161 tcatcatatt ttcagagcga tttttgggat cctgttccaa ccaactggcc tgttcaagat
    50221 cttcttggtc agttacccca cgctgagtcg tccccttcat tggtcgtgtt gtcaactcgc
    50281 gatcattttg ctcaaaaaag agctctgggc tcatggaaat cactgccatc tcgtcatgtt
    50341 ccacataggc attgtagccc gcctcctgct ctaccaccat acgattgtag atggcaaaag
    50401 gattggcact taacttttgc ttgagttgga cggtgtagtt gacctgatag gtgtctccct
    50461 gcctcaagtg atggtgtatc tgggcaatgg ccttttcata gtctgctgca gacgtcactt
    50521 cctgccaatt tgagggcaaa tcaatatcct cataagtcag aggaataggg gaggtctcta
    50581 ccctatcatg aacagtaaag taaagcaggt actctcccag taggggatcc ttgtgaactg
    50641 ctaatttttc ctcaaaagca ggggcagcct cgtagctgac ataccccacc acataataac
    50701 cttgctcttg gtagctttcc acttgtgcca gcaaatctgc cacttctgct acatttctcg
    50761 tttttatctc tttgataggc tgggtaaagg tgtatctctc ccccaaaatc ctaaaatcaa
    50821 tcactgtttt tctatgcata ccttaagtat agcataaaat aagaaaaccc tcatccgcaa
    50881 agcagatgag agatttcaat tatttaaaga ttgaagtttt aaagctattt gtttgttgaa
    50941 gaagtttctt ataaactttt tcttttactt gcacaagttt accattaact ttattagtaa
    51001 ccatatcttc ttcaagagct ttggcaaata atgattttaa ttcatcatag ttatgaatgg
    51061 tctcaccatc aatagtaaaa ggagtaaaac cagcgttggc tttttctaac aattctttat
    51121 aatattcttt cttaaaatca gcaaacgatt ggaatctgcc gtcagatatt ttttgtataa
    51181 tatattgatc tccaaattgt ttcccttctt tattagcttg agattttaat ttatctgaag
    51241 catatcctaa gaatccttta tcatagccat aatatcccca gagtctaaat gcattattct
    51301 taaatgtaac agcaccgggt gcaccatcac ttgtgttacc tgcatagata ctattcatca
    51361 ttttaattcc tacataggca atacctggat caaatacttc tggcttatat atattattat
    51421 tcatcatacg attagtcatc agattattat caactaagtc attaacactg tttaatgtta
    51481 ttcctttcca atcatcagag ctcatatttc gaaccttgtc atattgatct tttgacccta
    51541 cagtgcgttc aataggatca actttcttaa accacagttg atttaattta tcatcatgtt
    51601 tactaatgac tgcatcacct tcaacataat caagaagaga caaggtatct atatagcctt
    51661 tcatataatt atcaatgtct tctcttgttt taagagtctt cggatcggta atataccact
    51721 gatttccatc atttggacga tagaaagtca tattaattcc caaagcaccg tattcatcaa
    51781 accatgtact tggtactggt gtttgtaaca ttccttgtgc ataggcttct gcatgagtcc
    51841 ctgagcgacg tccatatcct cctaaataga ttgcacgatc attaacatga gtagtttcat
    51901 gtgtataaac agagattcca aactcatcaa tcatacttaa tgcaatataa tttacttctg
    51961 ttcgcgtatc caaaggatta tcccaaataa ctgcataagc acctgttcca ttgttaccat
    52021 aatacttacc aataggtcca aacaactctc tcaatggggc atagtcttct ttattatttc
    52081 tcttaccata cttatcaggc catccaccag gtgcttgata accttcccaa agaggagtta
    52141 ctgtattttt gactagcata ttcttaacct tatctaaaga taatctatac caaaaatcaa
    52201 aataatttcg ataactgtcc gctgcttttt caatctgatt ttttattcca tcgaaggagc
    52261 tatgccctaa cttttctgct gttccaacag ccattgcact ataattcgag attaaataca
    52321 catgtgattt atttagattt aataatggga gtatcatctt ccgatgagta gcagattgta
    52381 aattatccca aactttatat ttcgccgctt taatttcatc gacttccgaa gcacgctccg
    52441 ctatatagac attcccttct gtagctttct taaaccaatc ataaatattt acatctgcag
    52501 taaatagtcg acgattataa tttaaaaagt ttaccaaatt ttctgataag gttgtcttag
    52561 aaataatctc gctgaaagca tcatatgtcc gatgaccttt tatattatct tctcttgaac
    52621 cgatttcaat taatctatct aatacactta catttttacc atagaaatct ggtttgaata
    52681 acattaattc tttaatgtta acatcaccga atttaacacc gtagtaacgg tttaagtatg
    52741 ttaaacctaa taatagggca gctttatttt tctcaacttt atcaagaatc atttgttgag
    52801 ctgcagatga attattcagt tgatgatctt cattttcaac taatttagtt actaatatgt
    52861 ttaaattagc ttttacatgg tcaaaacttt cttctaaata aaggtcttta attgcattta
    52921 ctctattaga ccctgttctg ccaagttttt ggtaaattgg attagattga agctcaatag
    52981 ggcttaagat atttacgata ccgttaatta aagcactatg atctttttga acgatattag
    53041 gtgtatattt aatacctaag tcagttatag tgtattctct aacattactt agaccttcat
    53101 cactagaaga taggttgaag tagtcttttg ttccatcagc ataatgaacg ataattttgt
    53161 ttgcatcacc taaatcagtt acaaagttat tattgttcat aggagtaacc gatagaatct
    53221 ctttagtatt taacttgttg ttcttatcta gtttattagc ttgattaacg ataaaatctt
    53281 tgttatagaa tggttgtagt ttttcaatat tcttataagc aagtttatag tctgcattat
    53341 aatcttgaat agactcgtaa gctgcttcac gactgctaac attattcaat ttgttcaatt
    53401 cataaggttc acttacgaat ttagcagcag taatattgaa actagcaact tttgcatcag
    53461 cctcagattt agataagtgt tttaatttat ttttgttttt attatcttta ccagttccat
    53521 cttcagaaga gctatatcca ataactccaa ataaattaga cacaaaagga tttgcatctc
    53581 catcattaac atcgtttgaa ccgaatattt cctgaccttt aataactttc gcatatgtta
    53641 cattatcttg aaccgctcca tatggccaag ttttagaggt tattccacca acatatttag
    53701 tatttttaac atcaagaata ccttttgcta cagagtttgt aagttttcct tttgtccctg
    53761 atagccagct atgagcttta tattgaacga aaggaacaag catacttgca tttgcgttat
    53821 ttgctgtaat agtagcatca acgtaggctc tattaacaaa ccccatatag ttagaaccgg
    53881 caatacctcc aactgttgaa ttattaccag cagaatttat actaccgata aatgccacat
    53941 tttctaaagt agcgtcttct tttatgttat ttacgaaccc agcaacatta tttctagctg
    54001 ttatggttcc gattgctttg atattttcta tacgtgtcgt tccactgatt tcatttgcta
    54061 ttgcagcgat attatcttga ttagataaat caatatcaat attttcaaaa tttatatttt
    54121 taacagttcc agccttaatc ttatcgaata aaggatgttc caaattatgg atagcatagc
    54181 gtttatcacc atcactcaat agtttaccag taaactctga agtaatataa gatttccctt
    54241 taggaacaac gttacgagcg ctcatgcttt gacccagttt aaattcaccg gcaggatttg
    54301 tctgaatggc ttggatcaat tcttcaaagt cgtagaaaat accagcctga ctagctttgg
    54361 gtttttcaat atagtaggta taagtttctt caaagcgatt atcgacatta cgttggacca
    54421 agttatccgc tactgctatt accttgtaga cttgttttcc atcaattgtt gactcttcaa
    54481 ttttttgaac cgctagtaga ttggtcttat ggtcattaga ggtaactttt aaataataat
    54541 ttgacaaatc agttggcact gaagtcaatc gagtttcatc agtttcaact tggttttcat
    54601 atttgattaa atccgttctt ataatatctt ttatttcaac ttttttgaga tcaattctta
    54661 gcggttcttc tttcagaact tcttcctcat ccccctcacc acggtcataa accatctttg
    54721 tttcaagttt ataatccttg tagtactgca aatctgtcag ggtagttgtc aagtcttctg
    54781 gtgaaacatt caaggttttg acaatctcat cacctttttt cagagttagg gtaatagatt
    54841 taatggctgc cttacttgga ttttctaaac tatacttaac atctgaagta cgcttcaaat
    54901 ccttagattc aatttctgtg atggtcaaca ctggtttttc aaagctcttg gtaccacgtt
    54961 tcaaaatttt gtcttgaggt tcctcaagga tttcctctgt aacttttgga gcgtcttctg
    55021 ttttaactcc cttaatggta ttaaaggtct tggtgatttt tttctggcct tcttttcctt
    55081 cttgagctac aacttctaag ccttttttca gttggtcatc ttctttaaca acttccttaa
    55141 atggaatctt ttcaagactt tcttctataa gagttccttc aattggtttt gtaccacgga
    55201 ttacctgttg atttacaggc tccttggtca cttccgtact ggttgaaaga acttggtcag
    55261 ttttaacacc ttctactgtt ttataggttg tttttgtaac ttgacttcct ttttcaccag
    55321 ttcgtaggac agtttcttcg tccgtatact tggttggatc ctcagtcgtt tcagttttgt
    55381 agtctaggtc tgtagtcgat gtttcaacaa gggttccctc agttactttg tactcaggta
    55441 attgttcttg agcaagagcc tcacccacgt gacctttttc ttgcgtacct ttagctgttt
    55501 tagtctcctc ttttgattct actggttctt caaccttgat ttctggggct tctgctggct
    55561 gttcatcttc ttgtttcggt gtctcttccg ctcccctatc ttctttagga ttttcttgtt
    55621 gtgatgattc ttttggtgta cttggttgct cagcttgtgt aggttgcacg ggttgttctg
    55681 ggacttttgc ttgttctact ggtggttcaa cttttgattc ctcagctggt ttgtctgatg
    55741 gttgactttc tggcttaact gctacttttt cctctggttt tgactcaact tctccaccta
    55801 cttcttcaac tggagctggt tctgctgaat cttctttccc ctcttctact ttaggaaggg
    55861 tgtcgtcagt aggttttacc tccgattttg gttcttcctt tggactttct tctgttttag
    55921 gtgcttcttc ttttggagct tcctctgtct ctactacttg gttttctgtc ctagcttgct
    55981 cctgatttgt tgttgattga ggagtctcaa cttcgactac agtcacctct ccaggttttg
    56041 ctgaggtttc ttctaaaaca gtgtccaagc caagcgtttt gaggatgtca cctgatagat
    56101 aaccaacata gcgatagcca tccatttcaa caacaccctc tcgactagcc agcgctaggg
    56161 tcgcaactgg gtctacagcc cctgcactag gaagaactac caatcccata gctccaacta
    56221 gaaagacgct agcaattttc tttctcttgt agattaaaag caagctccca acagtcagca
    56281 aaccaaaagc tgtcaaaaca gatgcttctg tccctgtttg aggaaactga tctttttgat
    56341 acaccaaacc atatacaact tcattcctgt caggctttcc tgtctgaatt aaatctttag
    56401 cttcttgtga aataatctct ttatttacat agtgataggt ggctgcgtcc actacagaag
    56461 gagccatcaa aaggcttcca agaaatacag agcctacaac tcccttaatc ttacgaattg
    56521 aaaaacggtc ttttttaaac acttttatct cctttattca ttctcaagac tttctaatag
    56581 catcttgcgg atagtgcgca cgcgcacctc cgattaattt tggacgacta gccagtgccg
    56641 ttacatgggc atgaccaatc tctctcaaaa tagggcgaat cggaacctga acatgcttga
    56701 catgcatgcc aattgcagtg tctccgatat ccaatccagc atgagccttg ataaattcaa
    56761 cctcaactgg atcctgcata aacttaaagg ctgccaactg ccccgaacct cctgcatgaa
    56821 gagtaggatg gacactgaca atttccagat caaactgctc tgccacctga cgttcaacaa
    56881 cgagagcccg attgacatgc tcacaacctt gaactgctaa atggatacct ctactaccta
    56941 gaatacccaa gatagtctcc actatcagct caccaatctc ttgactggat tctttcccaa
    57001 tctgaccacc tagcacctca ctagaagata gacctaaaac aaaaaggacc ccctgcttca
    57061 aattggtctt ttctaaaaca tcttccacta cctgacgtgt ttctctttga atctgtgtct
    57121 cgttcatctc tgttacctct gttgttactc ttctatcata ccgttttttc ttgtttttag
    57181 caagatagac aacctagaaa gcttgcccaa ttacgcataa aactcccaga attgactggg
    57241 agttagctag tttctattct atttatatat atttcaactt tcgtcccttt ttggggtcta
    57301 gaatcaatct tcatctggta attggctcca aaatgaagtt tgagccgttg atcgacattt
    57361 tgaagaccaa ctcccccacg tttgagttga ctttgactac tatcaccagc atcttggaag
    57421 ccaacgccat catcctcaat acggatgacc aatcccgaat cctgtttctg gacagaaagt
    57481 ttaatatggc cctgaccttc cttttcctta atgccatggt aaagagcatt ttctacaagg
    57541 ggttgtagga ccagcttggg taagactaaa ttatcaaagg caacattttc attaatttcg
    57601 tattccagct tatctccata gcgttgtttc tggataaaga gatactggcg gacatgattg
    57661 atttcgtcag agagacaaat caagtctttg ccttgattga gcgccaagcg gaaataggtt
    57721 gccaaggact tggtcacctg caccactcgc tgactatcat gaaattcagc catccagatg
    57781 atggtgtcca aagtgttata gaggaaatgt ggattaatct ggctcgaaag ggcttgaagt
    57841 tggtactgac gggtcgtttc ttcctggcta cgaatagcta ccatcaactg atcaatctga
    57901 tccaacatgg cattaaattg gcgagttact tctctcagtt cataggcacc aacttccttg
    57961 gcacgaagat tttgagcacc agaagcaatt tccaacatgg tttctctcaa atccttcaaa
    58021 ggagcaatcc agcgtttaag actgaaccac actaagcaga gacaaacaag aagagatgtg
    58081 acactggccc caagcaaggt ccacaagagc tgactccgaa cctggtctaa cttttccaat
    58141 gatgacacgc caagtaccgt ccaatcagtt cctgcaatct tctcttgact gacgtaggat
    58201 ttgtgaccag gagtataacc ctgacctgtc tcgatgtagg gtttcatagc ctccattttg
    58261 ctagacgaac tataaactgt gtgttgagga tggtagacaa attcatggtt ttcattgata
    58321 atgaaggcaa agccctgctg ccccaactgg agttgattga gataggcttc cagagtttca
    58381 taagaaatat ccaaacgaag cacaccaaga ttggctccct ttgcatcaac aagttcttga
    58441 gtgacagaaa tgacccactg actatctgat ttacgagctg gagtcaaaac aggcatagct
    58501 ccctgatgaa tagccttttg gtaccaatcc tcagccatca tatcagagga agttttcatc
    58561 tgcacactgt catctgtaga aatgacctga ccagatttgg tcaccagcac aacagttttc
    58621 aagtccttat ctgacttcaa gatggtcaaa aacaaatctc ggattccctc gaccttgtct
    58681 tgactgggat tctcagcata ggccagaaca tccgtctgct gggtcaaacc agtcgaggtg
    58741 gtttctagtt ttttgatata agactgaata aagtggctag tctggctgat ggtcgtttgg
    58801 ctgttgccct caatggtggc ctcaatggct gaagaacttg attgatagta gaaagttcca
    58861 accagagcta ggagaatgag aaagaccaga aagatggaaa taaccattct aactaaaaga
    58921 gaagaacgct tcatcggtct tctcccttct taaactgacg aggtgtcaca cctgcaatct
    58981 gcttaaaacg ttgggtaaaa tagttcatat cttcaaaacc aaccttctct gcgatctcat
    59041 aaatcttcag atctgtagtt aaaagcaaga gcttggcttg tttaacacgt tctctcacca
    59101 gataatcctg aaaaggcaag cccaactctt tcttaatcaa ggaactcaga taggtcggac
    59161 taaaacctaa gtcactggct aaagacttta aactaaattg gctatcagcc agatgagact
    59221 ggattttctg ggccatgttt ccttcaaacc tattagtcaa taaatcttgt aactgctctt
    59281 ctttctcttc cttgtctagt ttttgtttga ttttccccaa catttcctca atatcctgac
    59341 gagaaaaggg tttgagcagg tagtcgtcca cacctagttt gacagcagac aaggcataat
    59401 caaaatcatc gtaacctgtt aaaaagacca aatgaacctg aggataggtt tctcgtacca
    59461 gactggccaa ctggatgcca tttagatgag gcatgttgat atcggttaaa atgatatctg
    59521 gcacctgctt ttggatcaat tcccaagcct gccttccatt ttcagcctga ccgatgattt
    59581 ccatatcgta ggctgctaca ttgaccagtt tagtcaaacc ttgtcttacc agatattcat
    59641 cttctacgat taagattgtg taggtcatgc tctgctcctt taccacttac tagtatcagt
    59701 atagcaaaat tctcctctaa ctgcttagga aagacctctt atactcaata aaaatcaaaa
    59761 agtaaactag gaagatagcc acaggtttct caaagtatag ctttgaggtt gta
//
LOCUS       DAVBOG010000008        49378 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.008, whole genome shotgun sequence.
ACCESSION   DAVBOG010000008 DAVBOG010000000
VERSION     DAVBOG010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 49378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49378
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.008"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(93..551)
                     /locus_tag="VQ865_000480"
     CDS             complement(93..551)
                     /locus_tag="VQ865_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3021 domain-containing protein"
                     /protein_id="HET3134892.1"
                     /translation="MKKQVFHDAAAGVLIGLILSILFSLIYAPNTYAPLNPYSLIGQV
                     MDQHQVHGALVLLYCTLIWAAIGMLFNFGNRLFSRDWSMLRATLTHFFLMLAGFVPLA
                     TLAGWFPFHWIFYLQLIIEFAIVYLIIWAILYKREAKKVDHINQLLEHRK"
     gene            complement(548..988)
                     /locus_tag="VQ865_000481"
     CDS             complement(548..988)
                     /locus_tag="VQ865_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3134893.1"
                     /translation="MKVELQISETYEEEKLIVQAPQPTDKVQKVIEFAENLDQREKIK
                     GKIDDQVYLVEIGKIQRFYIENRKVLAETASQTYSIDLRLYQVLKLLPTNFIQISQSE
                     IINIDSISHLKLTPNGLVEIFLKNESFTYSSRRYLKTIKEKLEL"
     gene            1194..3143
                     /gene="mutL"
                     /locus_tag="VQ865_000482"
     CDS             1194..3143
                     /gene="mutL"
                     /locus_tag="VQ865_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HET3134894.1"
                     /translation="MSHIIELPEMLANQIAAGEVIERPASVVKELVENAIDAGSSQII
                     IEIEEAGLKKVQITDNGHGIAHDEVELALRRHATSKIKNQADLFRIRTLGFRGEALPS
                     IASVSVLTLLTAVDGASHGTKLVARGGEVEEVIPATSPVGTKVCVEDLFFNTPARLKY
                     MKSQQAELSHIIDIVNRLGLAHPEISFSLISDGKEMTRTAGTGQLRQAIAGIYGLVSA
                     KKMIEIENSDLDFEISGFVSLPELTRANRNYISLFINGRYIKNFLLNRAILDGFGSKL
                     MVGRFPLAVIHIHIDPYLADVNVHPTKQEVRISKEKELMTLVSEAIANSLKEQTLIPD
                     ALENLAKSTVRNREKVDQTILPLKENTLYYEKTEPSRPSQTEVADYQVELTDEGQDLT
                     LFAKETLDRLTKPAKLHFAERKPANYDQLDHPELDLASIDKAYDKLEREEASSFPELE
                     FFGQMHGTYLFAQGRDGLYIIDQHAAQERVKYEEYRESIGNVDQSQQQLLVPYIFEFP
                     ADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCDMLLLTK
                     EVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSQCDNPYNCPHGRPVLVHF
                     TKSDMEKMFRRIQENHTSLRELGKY"
     gene            complement(3468..3935)
                     /locus_tag="VQ865_000483"
     CDS             complement(3468..3935)
                     /locus_tag="VQ865_000483"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HET3134895.1"
                     /translation="MNTYEGNLVANNIKIGIVVARFNEFITSKLLSGALDNLKRENVN
                     EKDIEVAWVPGAFEIPLIASKMAKSKKYDAIICLGAVIRGNTSHYDYVCSEVSKGIAQ
                     ISLNSEIPVMFGVLTTDTIEQAIERAGTKAGNKGSECAQGAIEMVNLIRTLDA"
     gene            complement(3936..5141)
                     /locus_tag="VQ865_000484"
     CDS             complement(3936..5141)
                     /locus_tag="VQ865_000484"
                     /EC_number="3.5.4.25"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP
                     cyclohydrolase II"
                     /protein_id="HET3134896.1"
                     /translation="MEYRKIQEALEALQKGRLVLVIDDKDRENEGDLICSAQAATTEN
                     VNFMATYAKGLICMPMSESLANQLMLSPMVENNTDNHKTAFTVSIDYKETTTGISAEE
                     RGLTARMCVAEDITPSDFRRPGHMFPLIAKKGGVLERNGHTEATVDLLKLAGLKECGL
                     CCEIMNHDGKMMRTDDLIQFSKKHNIPLITIKELQEYRKVYDQLVERVSTVNMPTRYG
                     NFKAISYIDKLNGEHHLALIMGNIEDEANVLCRVHSECLTGDVLGSLRCDCGQQFDKA
                     MKMIVENGSGVLLYLRQEGRGIGLINKLKAYHLQDQGMDTLDANLALGFEGDLREYHI
                     GAQMLKDLGLQSLHLLTNNPDKVEQLEKYGITISSRISIEIEANPYDSFYLETKKNRM
                     GHILNMEEK"
     gene            complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ865_000485"
     CDS             complement(5161..5796)
                     /gene="ribE"
                     /locus_tag="VQ865_000485"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HET3134897.1"
                     /translation="MFTGIIEEIGKVERIQKDSRNCKLSIKASKILTDIHLGDSIAVN
                     GICLTVTHFNHQSFTVDVMNETWSRTALTLLKHGSEVNLERALSVNGRLGGHVVTGHI
                     DGTGKISSIKKDDNAVWYQINTQKEILDLIVEKGSITIDGISLTVAKVSKVNFSVSVI
                     PHTLEQTILKSKQVGSTVNLENDILGKYVQKLMDNSPKSEISKELLYQNGF"
     gene            complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ865_000486"
     CDS             complement(5781..6881)
                     /gene="ribD"
                     /locus_tag="VQ865_000486"
                     /EC_number="1.1.1.193"
                     /EC_number="3.5.4.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HET3134898.1"
                     /translation="MSDSKYMKLAIKLAQKGAGYVNPNPMVGAIIVKDNHIIGQGYHE
                     FFGGPHAERNALKNCRKSPVGATLYVTLEPCCHFGKTPPCIDAIIDSGITRVVIGSLD
                     CNPIVSGKGVKILEENNLQVTVGILENECLNLIKSFRKYITQHVPYVFMKYAMSMDGK
                     IATKTNQSKWITEEEARKHVHQLRHHVSAIMVGVNTVIQDDPLLTCRLEEGKNPIRII
                     CDTHLRTPLTSKIVKTANDIKTYIATSSEDKNKMKLYQNHGCEILSIKKKGNHIDLSS
                     LMQHLGNMQIDSLVLEGGSLMNWSALEQQIVDELKIYIAPKIFGGSAKFPVGGEGISL
                     PNDAIRLKPYAFSQIGNDYLIESEVIYPCSQE"
     regulatory      complement(7015..7129)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ865_000487"
     CDS             7286..7879
                     /gene="ruvA"
                     /locus_tag="VQ865_000487"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HET3134899.1"
                     /translation="MYAYLKGIITKITAKYIVLETNGIGYILHVANPYAYSGQVNQED
                     QIYVHQVVREDAHLLYGFRSEDEKKLFLSLISVSGIGPVSALAIIAADDNAGLVQAIE
                     TKNITYLTKFPKIGKKTAQQMVLDLEGKVVVAGDDLPAKVAVQASAENQELEEAMEAM
                     LALGYKATELKKIKKFFEGTTDTAENYIKSALKMLVK"
     gene            7889..8452
                     /locus_tag="VQ865_000488"
     CDS             7889..8452
                     /locus_tag="VQ865_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HET3134900.1"
                     /translation="MTKRCSWVKMTNPLYIAYHDEEWGQPLHDDQALFELLCMETYQA
                     GLSWETVLNKRQAFREAFHSYQIHSVAEMTDTELEAMLENPAIIRNRAKIFATRANAQ
                     AFLQLQAEYGSFDAYLWSFVEGKTVVNDVPDYRQAPAKTPLSEKLAKDLKKRGFKFTG
                     PVAVLSFLQAAGLVDDHENDCEWKGLK"
     gene            8449..9126
                     /locus_tag="VQ865_000489"
     CDS             8449..9126
                     /locus_tag="VQ865_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000987430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3134901.1"
                     /translation="MMSNKNKGILIFAILYTILFVFDGVKLLASLMPSVIANYLVYVV
                     LALYGSFLFKDRLIQQWKEIRKTKRKFFFGVLTGWLFLILMTVVFEFVSEMLKQFVGL
                     DGQGLNQSNIQSTFQEQPLLIAVFACVIGPLVEELFFRQVLLHYLQERLPGLLSIILV
                     GLVFALTHMHSLALSEWIGAVGYLGGGLAFSIIYVKEKENIYYPLLVHMLSNSLSLII
                     LAISIVK"
     gene            complement(9263..10294)
                     /locus_tag="VQ865_000490"
     CDS             complement(9263..10294)
                     /locus_tag="VQ865_000490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000255096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HET3134902.1"
                     /translation="MVSTIGIVSLSSGIIGEDFVKHEVDLGIQRLKDLGLNPIFLSHS
                     LKGLDFIKDHPEARAEDLIHAFSDDSIDMILCAIGGDDTYRLLPYLFENDQLQKVIKQ
                     KIFLGFSDTTMNHLMLHKLGIKTFYGQSFLADICELDKEMLAYSLHYFKELIKTGRIS
                     EIRPSDVWYEERTDFSPTALGTPRVSHTNTGFDLLQGSAQFEGKILGGCLESLYDIFD
                     NSRYADSTELCQKYKLFPDLSDWEGKILLLETSEEKPKPEDFKKMLLTLKDTGIFAVI
                     NGLLVGKPMDETFHDDYKEALLDIIDSNIPIVYNLNVGHATPRAIVPFGVHAHVDAQE
                     QVILFDYNK"
     gene            complement(10549..11232)
                     /locus_tag="VQ865_000491"
     CDS             complement(10549..11232)
                     /locus_tag="VQ865_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HET3134903.1"
                     /translation="MSQIDLQKLTKKNQEFVHIATQQFIKDGKTDAEIQTIFEEVIPQ
                     ILEEQSKGTTARSLYGAPTHWAHSFTVKEQYEKEHPKENDDPKLMIMDSALFITSLFA
                     LVSALTTFFAADQAFGYGLITLLLVGLVGGFAFYLMYYFVYQYYGSDMDRSQRPPFWK
                     SVLVILASMFLWLLVFFATSFLPASLNPVLDPLPLAIIGAALLALRFYLKKRLNIRSA
                     SAGPTRYQE"
     gene            complement(11244..12188)
                     /locus_tag="VQ865_000492"
     CDS             complement(11244..12188)
                     /locus_tag="VQ865_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3134904.1"
                     /translation="MKQVFLSTTTEFKEIDTLEPGTWINLVNPTQNESLEIANTFDID
                     IADLRAPLDAEEMSRITIEDEYTLIIVDVPVTEERNNRTYYVTIPLGIIITEETIITT
                     CLEPLPVLDVFINRRLRNFYTFMRSRFIFQILYRNAELYLTALRSIDRKSEQIESQLH
                     QSTRNEELIELMELEKTIVYFKASLKTNERVIKKLTSSTSNIKKYLEDEDLLEDTLIE
                     TQQAIEMADIYGNVLHSMTETFASIISNNQNNIMKTLALVTIVMSIPTMVFSAYGMNF
                     KDNEIPLNGEPNAFWLIVFIAFAMSVSLTLYLIHKKWF"
     gene            12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ865_000493"
     CDS             12320..15151
                     /gene="uvrA"
                     /locus_tag="VQ865_000493"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HET3134905.1"
                     /translation="MQDKIVIHGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFD
                     TLYAEGQRRYVESLSAYARQFLGNMEKPDVDAIDGLSPAISIDQKTTSKNPRSTVGTT
                     TEINDYLRLLYARVGTPYCINGHGAINASSVEQIVDKVLELPERQRLQILAPVIRKKK
                     GQHKSVIEKVQKDGYVRVRVDGEVYDVTEVPELSKSKQHNIDVVVDRIVIKEGIRSRL
                     FDSIEAALRIAEGYVIIDTMDDSELLFSEHYACPVCGFTVPELEPRLFSFNAPFGSCS
                     ECDGLGIKLEVDTDLVVPDASKTLHEGALAPWNPISSNYYPNMLEQAMKVFGVAMDKP
                     FEDLSEEDKNLILYGSDGKEFHFHYENEFGGVRDIDIPFEGVINNIKRRYHETNSDYT
                     RTQMRLYMNELTCGTCQGYRLNDQALSVRVGGQQGPHIGEISDLSIADHLDLVSQLTL
                     SENEAIIARPILKEIKDRLTFLNNVGLNYLTLSRSAGTLSGGESQRIRLATQIGSNLS
                     GVLYILDEPSIGLHQRDNDRLIASLKKMRDLGNTLIVVEHDEDTMREADYLIDVGPGA
                     GVFGGEIVAAGTPKQVARNSKSITGQYLSGKRVIPVPEERRVGNGRFIEVTGARENNL
                     QNVTARFPLGKFIAVTGVSGSGKSTLINSILKKAIAQKLNRNSDKPGKFKTITGIEHV
                     DRLIDINQSPIGRTPRSNPATYTGVFDDIRDLFAQTNEAKIRGYKKGRFSFNVKGGRC
                     EACSGDGIIKIEMHFLPDVYVACEVCHGTRYNSETLEVHYKEKNISQVLDMTVNDAVE
                     FFQHIPKIQRKLQTIKDVGLGYVTLGQPATTLSGGEAQRMKLASELHKRSTGKSFYIL
                     DEPTTGLHTEDIARLLKVLARFVDAGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGT
                     IIVTGTPEEVAANEASYTGHYLKGKLHHE"
     gene            15144..16205
                     /locus_tag="VQ865_000494"
     CDS             15144..16205
                     /locus_tag="VQ865_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HET3134906.1"
                     /translation="MNKRVQAFLAKMQEKELDGIIINNLKNVYYLTGFWGSNGTVFIS
                     RDRQVLVTDSRYIIAAKQETSGFEIVADRDELAVIAGIVKDMNLTRIGFEDEISVSYY
                     HRMQAAFAGLNLLPQTQFVEGLRMIKDEAEIAAIRKACSISDQAFRDALDFIKPGKTE
                     IEIANFLDFRMRELGASGLSFDTILASGINSSKPHAHPMHKPVELGEAITMDFGCLYD
                     HYVSDMTRTIYLGHVSDEQAEIYNTVLKANQALIDQAKAGLGFRDFDKIPRDIIIEAG
                     YGDYFTHGIGHGIGLDIHEEPYFSQTSTETIKTGMALTDEPGIYIEGKYGVRIEDDIL
                     ITETGCELLTLAPKELIVI"
     gene            16337..16735
                     /gene="spx"
                     /locus_tag="VQ865_000495"
     CDS             16337..16735
                     /gene="spx"
                     /locus_tag="VQ865_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017768833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HET3134907.1"
                     /translation="MIKIYTVSSCTSCKKAKTWLNAHQLSYKEQNLGKEGITREELLD
                     ILTKTDNGIASIVSSKNRYAKALGVDIEDLSVNEVLNLIMETPRILKSPILVDEKRLQ
                     VGYKEDDIRAFLPRSVRNVENAEARLRAAL"
     gene            16801..17370
                     /locus_tag="VQ865_000496"
     CDS             16801..17370
                     /locus_tag="VQ865_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3134908.1"
                     /translation="MKKIVLVSLAFLFVLVGCGQKKETGPATKTEKDTLQSALPVIEN
                     AEKNTVVTKTLVLPKSDDGSQQTQTITYKDKTFLSLAIQQKRPVSDELKTYIDQHGVE
                     ETQKALLEAEEKDKSIIEARKLAGFKLETKLLSATELQTTTSFDFQVLDVKKASQLEH
                     LKNIGLENLLKNEPSKYISDRLANGATEQ"
     gene            17457..17723
                     /locus_tag="VQ865_000497"
     CDS             17457..17723
                     /locus_tag="VQ865_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004250500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HET3134909.1"
                     /translation="MGFTEETVRFKLDDSNKKEISETLTDVYASLNDKGYNPINQIVG
                     YVLSGDPAYVPRYNNARNQIRKYERDEIVEELVRYYLKGQGVDL"
     gene            17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ865_000498"
     CDS             17727..18146
                     /gene="ruvX"
                     /locus_tag="VQ865_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002939356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HET3134910.1"
                     /translation="MRIMGLDVGSKTVGVAISDPLGFTAQGLEIIQINEEQGQFGFDR
                     VKELVDTYKVERFVVGLPKNMNNTSGPRVEASQAYGAKLEEFFGLPVDYQDERLTTVA
                     AERMLIEQADISRNKRKKVIDKLAAQLILQNYLDRKF"
     gene            18162..18467
                     /locus_tag="VQ865_000499"
     CDS             18162..18467
                     /locus_tag="VQ865_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HET3134911.1"
                     /translation="MSHDHNHDHEERELITLVDEQGNETLFEILLTIDGKEEFGKNYV
                     LLVPVNAEEDEDGQVEIQAYSFIENEDGTEGELQPIPEDSEDEWNMIEEVFNSFMEE"
     gene            18773..20023
                     /locus_tag="VQ865_000500"
     CDS             18773..20023
                     /locus_tag="VQ865_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3134912.1"
                     /translation="MFEVEEWLHSRIGLNFRSGLGRMQQAVDLLGNPEQSYPIIHVTG
                     TNGKGSTIAFMRELFMGHGKKVATFTSPHIVSINDRICINGQPIADADFIRLADQVKE
                     MEKTLLQTPDQLSFFELLTLVAFLYFREQEVDLVLLEVGIGGLLDTTNVVTGELAVIT
                     SIGLDHQETLGDSLEAIAEQKAGIFKAGKKAVIAKLPPEARLVCQKKAESLAVDLYQA
                     GQDFSVLNGDFSSSLLNLSQLNIGLEGAYQQENAALALQTFLLFMGERKEAIDEQAVR
                     KALEQTHWAGRLERIRPQIYLDGAHNLPALTRLVEFIKEKEQEGYRPQILFGSLKRKD
                     YQGMLGYLTENLPQVELKMTGFDYQGSLDETDVTGYHVIPSYREFISSFEERADAQDL
                     LFVTGSLYFISEVRGYLLDREQIN"
     gene            20020..20562
                     /locus_tag="VQ865_000501"
     CDS             20020..20562
                     /locus_tag="VQ865_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin/fatty acid-binding family protein"
                     /protein_id="HET3134913.1"
                     /translation="MTPFFELVILGELLVRENFSKLVAERKFIMKLKRFTLSLASLAS
                     FSLLVACSQRAQQVQQPVAQQVQQPAQQNTNTANAGGNQNQAAPVQNQPVAQPTDIDG
                     TYTGQDDGDRITLVVTGTTGTWTELESDGDQKVKQVTFDSANQRMIIGDDVKIYTVNG
                     NQIVVDDMDRDPSDQIVLTK"
     gene            20708..22240
                     /gene="cls"
                     /locus_tag="VQ865_000502"
     CDS             20708..22240
                     /gene="cls"
                     /locus_tag="VQ865_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000877342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HET3134914.1"
                     /translation="MKYRKFQLLMSKYGFSLSIMLLELCLVFGLFLYLGRMAPILWIT
                     VLILLSIITIISIVNRNTTPENKVTWLLVAFVPVFGPLLYLMFGERRLSKKEIKQLKK
                     LGSMHFQEANSQLLKEKLKESDKAAYGVIKSLLSMDTNADIYDQTASTFFPNGEAMWK
                     KMVEDLKKAEKFIFLEYYIIEEGLMWNRILDILEQKVAQGVEVKMLYDDIGCMATLTG
                     DYAHRLRQLGIEAHKFNKVIPRLTVAYNNRDHRKILIVDGQIAYTGGVNLADEYINHV
                     ERFGYWKDSGIRLDGLAVKALTRLFLTTWYINRGEISDFDQYHLENHSIPSDGLTIPY
                     GSGPKPIFRAQVGKKVYQSLINQATESVYITTPYLIIDYDLTETIKNAAMRGVDVRII
                     TPYIPDKKFIQLVTRGAYPDLLSAGVRIYEYSPGFIHSKQMLVDEDFAVVGTINLDYR
                     SLVHHYENAVLLYKTPSIREIARDFRNIFADSQEVYPHSIKTSWYQKLVKEIAQLFAP
                     IL"
     gene            22498..24036
                     /locus_tag="VQ865_000503"
     CDS             22498..24036
                     /locus_tag="VQ865_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3134915.1"
                     /translation="MSVYGRVEEVHKENREPLEYQIEQESHHRESSRLPLVKILLWST
                     LVTGITLGVPLLLDLMSAQEVQDFYAGWALHQTGKIYSDYYGSQGLLYYLLTYVSQGG
                     FFFAIFEWLALVAGGFFLFRSADTLTEQGDQAGHLVTIFYMLVTGLAFGGGYATLLAL
                     PFLFAAFSLVAAYLSNPSHDKGFVRIGLALAGGFFFAPLSSLLFIAVVGLGLLVFNLG
                     HRRFAHGFYQFLAVALGFSLVFYPTAYYSAATGSFGDAISGIRYPIDSIRFDFTSKIL
                     ENMFFYGLLSLGLGFVVCIFLGLFQSKPFKLYVISVPASLVVILGLILLFFSQEPLHA
                     SYLMVVFPVFLLLLVTNIKSQQRGRSARRSRRETPVSLWSRFFKGNLYLLVFGFVYLL
                     SVPFLMKFVLYPVPYQERNRLADLVKEETNTEDAIYAWDDTATLYRKSERLSPSAILS
                     PLHYTATEENRNKLLNDLKEKQPKVIVVNDKVVVWSEVETLLKENYQQVKTDYSEFKV
                     YKIK"
     gene            24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ865_000504"
     CDS             24156..26363
                     /gene="nrdD"
                     /locus_tag="VQ865_000504"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004239081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HET3134916.1"
                     /translation="MIALEEKITILPTLFVEKRDGRRVVFDVDKIDKALHKAADKVMD
                     VTPLVEKRLNDLTERIITEIHSRFPQGIKIYEIQNIVEHELLEAKEYALAEEYITYRT
                     QRDFERSKATDINFSIHKLLNKDQTVVNENANKDSDVFNTQRDLTAGIVGKSIGLQML
                     PKHVANAHQKGDIHYHDLDYSPYTPMTNCCLIDFKGMLENGFKIGNAEVESPKSIQTA
                     TAQISQIIANVASSQYGGCSADRIDEILAPYAEKNYQKHLKDAEEWVLPEKREDYAWK
                     KTQKDIYDAMQSLEYEINTLFTSNGQTPFTSLGFGLGTSRFEREIQKAILNIRIKGLG
                     SEHRTAIFPKLIFTLKRGLNLEEGTPNYDIKQLALECATKRMYPDVLSYDKIVDLTGS
                     FKVPMGCRSFLQGWKDENGVEVNSGRMNLGVVTVNLPRIALESEGDMNKFWEIFNERM
                     NIAEDALVYRVERTKEATPANAPILYQYGAFGHHLGKEESVDQLFKNRRATVSLGYIG
                     LYEVATVFFGNSWESNPDAKEFTLDIIHDMKRRVEEWSDQYGYHFSIYSTPSESLTDR
                     FCRLDIDKFGSIPDITDKEYYTNSFHYDVRKNPTPFEKLDFEKVYPEAGASGGFIHYC
                     EYPVLQQNPKALEAVWDYAYDRVGYLGTNTPIDRCYKCDFEGDFEPTERGFACPNCGN
                     SDPKTVDVVKRTCGYLGNPQARPMVNGRHKEIAARVKHMNGSTIKIAGHQVTN"
     gene            26375..26515
                     /locus_tag="VQ865_000505"
     CDS             26375..26515
                     /locus_tag="VQ865_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134917.1"
                     /translation="MGKYQLDDKGRAQVTRYHEKHSKGGAGKKERLLSFREQFLNKNK
                     KK"
     gene            26559..27065
                     /locus_tag="VQ865_000506"
     CDS             26559..27065
                     /locus_tag="VQ865_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000423398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3134918.1"
                     /translation="MELRRPRLADKKAVLDMMTEFEKFQSPHDGGFWDTENFVYEDWL
                     ESNQEQEMGINLPEGWVPAIQLVAFSEKGQAVGFLNLRLRLSNFLLEEGGHIGYSIRP
                     SERGKGYAKETLRQGLQVAKEKNIKKALVTCSVNNPASRAVILANGGIFEDARNGVER
                     YWIEVANE"
     gene            27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ865_000507"
     CDS             27058..27648
                     /gene="nrdG"
                     /locus_tag="VQ865_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HET3134919.1"
                     /translation="MNNPKPQEWKSEELSQGRIIDYKAFNFVDGEGVRNSLYVAGCMF
                     HCEGCYNVATWSFNAGIPYTAELEEQIMADLGQPYVQGLTLLGGEPFLNTGILLPLVK
                     RIRKELSDKDIWSWTGYTWEEMMLETPDKLELLSLIDILVDGRYDRTKRNLMLQFRGS
                     SNQRIIDVQKSLKSGQVVIWDKLNDGKESYEQVKRE"
     gene            27645..28262
                     /locus_tag="VQ865_000508"
     CDS             27645..28262
                     /locus_tag="VQ865_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000725987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HET3134920.1"
                     /translation="MKKKGLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELSQALD
                     STTVNLLETDPYITSGRYLVVPKDAPNQKVTASLPVAYELESLQRDIFALQAGMDVLT
                     IEEPWKASEVLSGAKPILIVEGMSVGFLPKELFEKTICFYTDEETELKRRLARDTTVR
                     NRDASFILASHQMRREQYLRYYKETESKADILVDQSEDKFDVKRT"
     gene            28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ865_000509"
     CDS             28517..28825
                     /gene="rpsJ"
                     /locus_tag="VQ865_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HET3134921.1"
                     /translation="MANKKIRIRLKAYEHRTLDTAAAKIVESATRTGAQVAGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTQKTVDALMKLDLPSGVNVEIKL
                     "
     gene            29042..29668
                     /gene="rplC"
                     /locus_tag="VQ865_000510"
     CDS             29042..29668
                     /gene="rplC"
                     /locus_tag="VQ865_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002986659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HET3134922.1"
                     /translation="MTKGILGKKVGMTQIFTEAGELIPVTVIEATPNVVLQVKTVETD
                     GYNAIQVGFDDKREVLSNKPAKGHVAKANTAPKRFIREFKNVEGLEVGAEITVETFAA
                     GDVVDVTGTSKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKGKNLAG
                     RMGGDRVTIQNLEVVQVVPEKNVILIKGNVPGAKKSLITIKSAVKAGK"
     gene            29693..30316
                     /gene="rplD"
                     /locus_tag="VQ865_000511"
     CDS             29693..30316
                     /gene="rplD"
                     /locus_tag="VQ865_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HET3134923.1"
                     /translation="MANVTLFDQTGKEAGQVVLSDAVFGIEPNESVVFDVIISQRASL
                     RQGTHAVKNRSAVSGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYGYKLP
                     QKVRRLALKSVYSEKVAENKFVAVDALSFTAPKTAEFAKVLAALSIDSKVLVILEEGN
                     EFAALSARNLPNVKVATATTASVLDIANSDKLLVTQAAISKIEEVLA"
     gene            30316..30612
                     /locus_tag="VQ865_000512"
     CDS             30316..30612
                     /locus_tag="VQ865_000512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007518994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HET3134924.1"
                     /translation="MNLYDVIKKPVITESSMAQLEAGKYVFEVDTRAHKLLIKQAVEA
                     AFEGVKVANVNTINVKPKAKRVGRYTGFTNKTKKAIITLTADSKAIELFAAEAE"
     gene            30630..31463
                     /gene="rplB"
                     /locus_tag="VQ865_000513"
     CDS             30630..31463
                     /gene="rplB"
                     /locus_tag="VQ865_000513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019790357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HET3134925.1"
                     /translation="MGIRVYKPTTNGRRNMTSLDFAEITTSTPEKSLLVALKSKAGRN
                     NNGRITVRHQGGGHKRFYRLVDFKRNKDNVEAVVKTIEYDPNRSANIALVHYTDGVKA
                     YIIAPKGLEVGQRIVSGPEADIKVGNALPLANIPVGTLIHNIELKPGRGGELVRAAGA
                     SAQVLGSEGKYVLVRLQSGEVRMILGTCRATVGVVGNEQHGLVNLGKAGRSRWKGIRP
                     TVRGSVMNPNDHPHGGGEGKAPVGRKAPSTPWGKPALGLKTRNKKAKSDKLIVRRRNE
                     K"
     gene            31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ865_000514"
     CDS             31567..31848
                     /gene="rpsS"
                     /locus_tag="VQ865_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HET3134926.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQANDEKKKVIKTWSRRSTIFPSF
                     IGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYKGHAADDKKTRRK"
     gene            31860..32204
                     /gene="rplV"
                     /locus_tag="VQ865_000515"
     CDS             31860..32204
                     /gene="rplV"
                     /locus_tag="VQ865_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HET3134927.1"
                     /translation="MAEITSAKAMARTVRVSPRKSRLVLDNIRGKSVADAIAILTFTP
                     NKAAEIILKVLNSAVANAENNFGLDKANLVVSEAFANEGPTMKRFRPRAKGSASPINK
                     RTAHITVAVAEK"
     gene            32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ865_000516"
     CDS             32217..32870
                     /gene="rpsC"
                     /locus_tag="VQ865_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HET3134928.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYADYLHEDLAIRKFVQK
                     ELADAAVSTIEIERAVNKVNVSLHTAKPGMVIGKGGANVDALRAKLNKLTGKQVHINI
                     IEIKQPDLDAHLVGEGIARQLEQRVAFRRAQKQAIQRAMRAGAKGIKTQVSGRLNGAD
                     IARAEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEVLPARKNTKGGK"
     gene            32874..33287
                     /gene="rplP"
                     /locus_tag="VQ865_000517"
     CDS             32874..33287
                     /gene="rplP"
                     /locus_tag="VQ865_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003029477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HET3134929.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQATTSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKV
                     MFEIAGVSEEIAREALRLASHKLPVKCKFVKREAE"
     gene            33297..33503
                     /locus_tag="VQ865_000518"
     CDS             33297..33503
                     /locus_tag="VQ865_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006739716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HET3134930.1"
                     /translation="MKLNEVKEFVKELRGLSQEELAKRENELKKELFELRFQAATGQL
                     EQTARLKEVKKQIARIKTVQSEAK"
     gene            33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ865_000519"
     CDS             33528..33788
                     /gene="rpsQ"
                     /locus_tag="VQ865_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HET3134931.1"
                     /translation="MERNNRKVLVGRVVSDKMDKTITVVVETKRNHPVYGKRINYSKK
                     YKAHDENNVAKEGDIVRIMETRPLSATKRFRLVEVVEEAVII"
     gene            33814..34182
                     /gene="rplN"
                     /locus_tag="VQ865_000520"
     CDS             33814..34182
                     /gene="rplN"
                     /locus_tag="VQ865_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HET3134932.1"
                     /translation="MIQTETRLKVADNSGAREILTIKVLGGSGRKFANIGDVIVASVK
                     QATPGGAVKKGDVVKAVIVRTKSGARRADGSYIKFDENAAVIIREDKTPRGTRIFGPV
                     ARELREGGFMKIVSLAPEVL"
     gene            34260..34565
                     /gene="rplX"
                     /locus_tag="VQ865_000521"
     CDS             34260..34565
                     /gene="rplX"
                     /locus_tag="VQ865_000521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011921687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HET3134933.1"
                     /translation="MFVKKGDKVRVIAGKDKGTEAVVLTALPKVNKVIVEGVNIVKKH
                     QRPTNELPQGGIIEKEAAIHVSNVQVLDKNGVAGRVGYKFVDGKKVRYNKKSGEVLD"
     gene            34589..35131
                     /gene="rplE"
                     /locus_tag="VQ865_000522"
     CDS             34589..35131
                     /gene="rplE"
                     /locus_tag="VQ865_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HET3134934.1"
                     /translation="MANRLKEKYLNEVVPALTEQFNYSSVMAVPKVDKIVLNMGVGEA
                     VSNAKSLEKAAEELALISGQKPLITKAKKSIAGFRLREGVAIGAKVTLRGERMYEFLD
                     KLVSVSLPRVRDFHGVPTKSFDGRGNYTLGVKEQLIFPEINFDDVDKTRGLDIVIVTT
                     ANTDEESRALLTGLGMPFAK"
     gene            35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ865_000523"
     CDS             35149..35418
                     /gene="rpsN"
                     /locus_tag="VQ865_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006738440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HET3134935.1"
                     /translation="MAKKSMVAREAKRQKIVDRYAEKRAALKAAGDYEGLSKLPRNAS
                     PTRLHNRCRVTGRPHSVYRKFGLSRIAFRELAHKGQIPGVTKASW"
     gene            35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ865_000524"
     CDS             35703..36101
                     /gene="rpsH"
                     /locus_tag="VQ865_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009754342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HET3134936.1"
                     /translation="MVMTDPIADFLTRIRNANQAKHEVLEVPASNIKKGIAEILKREG
                     FVKNVEIIEDDKQGVIRVFLKYGPNGEKVITNLKRVSKPGLRVYKKREDLPKVLNGLG
                     IAILSTSEGLLTDKEARQKNVGGEVIAYVW"
     gene            36293..36829
                     /gene="rplF"
                     /locus_tag="VQ865_000525"
     CDS             36293..36829
                     /gene="rplF"
                     /locus_tag="VQ865_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HET3134937.1"
                     /translation="MSRIGNKVIVLPAGVELANNDNVVTVKGPKGELTREFSKDIEIR
                     VEGTEVTLHRPNDSKEMKTIHGTTRALLNNMVVGVSEGFKKELEMRGVGYRAQLQGSK
                     LVLAVGKSHPDEVEAPEGITFELPNPTTIVVSGISKEVVGQTAAYVRSLRSPEPYKGK
                     GIRYVGEFVRRKEGKTGK"
     gene            36913..37269
                     /gene="rplR"
                     /locus_tag="VQ865_000526"
     CDS             36913..37269
                     /gene="rplR"
                     /locus_tag="VQ865_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HET3134938.1"
                     /translation="MISKPDKNKLRQKRHRRVRGKLSGTADRPRLNVFRSNTGIYAQV
                     IDDVAGVTLASASTLDKEVSKGTKTEQAVAVGKLVAERANAKGISEVVFDRGGYLYHG
                     RVKALADAARENGLKF"
     gene            37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ865_000527"
     CDS             37287..37781
                     /gene="rpsE"
                     /locus_tag="VQ865_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HET3134939.1"
                     /translation="MAFKDNAVELEERVVAVNRVTKVVKGGRRLRFAALVVVGDHNGR
                     VGFGTGKAQEVPEAIRKAVDDAKKNLIEVPMVGTTIPHEVLSEFGGAKVLLKPAVEGS
                     GVAAGGAVRAVVELAGVADITSKSLGSNTPINIVRATVEGLKQLKRAEEIAALRGISV
                     SDLA"
     gene            37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ865_000528"
     CDS             37753..37977
                     /gene="rpmD"
                     /locus_tag="VQ865_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HET3134940.1"
                     /translation="MVFQFLIWHKKGDKMAQIKITLTKSPIGRIPSQRKTVVALGLGK
                     LNSSVIKEDNAAIRGMITAVSHLVTVEEVN"
     gene            38122..38562
                     /gene="rplO"
                     /locus_tag="VQ865_000529"
     CDS             38122..38562
                     /gene="rplO"
                     /locus_tag="VQ865_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004225266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HET3134941.1"
                     /translation="MKLHELKPAEGSRKVRNRVGRGTSSGNGKTSGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNINAKEYAIVNLDQLNVFEDGAEVTPVVLIEAGIV
                     KAEKSGIKILGNGELTKKLTVKAAKFSKSAEEAITAKGGSVEVI"
     gene            38575..39885
                     /gene="secY"
                     /locus_tag="VQ865_000530"
     CDS             38575..39885
                     /gene="secY"
                     /locus_tag="VQ865_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HET3134942.1"
                     /translation="MFFKLLREALKVKQVRSKILFTIFIVLVFRIGTSITVPGVNANS
                     LNALSGLSFLNMLSLVSGNALKNFSIFALGVSPYITASIVVQLLQMDILPKFVEWGKQ
                     GEVGRRKLNQATRYIALVLAFVQSIGITAGFNTLAGAQLIKTALTPQVFLTIGIILTA
                     GSMIVTWLGEQITDKGYGNGVSMIIFAGIVSSIPEMIQGIYVDYFVNVPSSRITSSII
                     FVIILIITVLLIIYFTTYVQQAEYKIPIQYTKVAQGAPSSSYLPLKVNPAGVIPVIFA
                     SSITAAPAAILQFLSATGHDWAWVRVAQEMLATTSPTGIAMYALLIILFTFFYTFVQI
                     NPEKAAESLQKSGAYIHGVRPGKGTEEYMSKLLRRLATVGSLFLGVISILPIAAKDVF
                     GLSDVVAFGGTSLLIIISTGIEGIKQLEGYLLKRKYVGFMDRTE"
     gene            40036..40674
                     /locus_tag="VQ865_000531"
     CDS             40036..40674
                     /locus_tag="VQ865_000531"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001050429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HET3134943.1"
                     /translation="MNLLIMGLPGAGKGTQAAKIVEQFHVAHISTGDMFRAAMANQTE
                     MGVLAKSYIDKGELVPDEVTNGIVKERLSQDDIKETGFLLDGYPRTIEQAHALDKTLA
                     ELGIELEGIINIEVNPDSLLERLSGRIIHRVTGETFHKVFNPPVDYKEEDYYQREDDK
                     PETVKRRLDVNIAQGEPIIAHYRAKGLVHDIEGNQDINDVFSDIEKVLTNLK"
     gene            40791..41009
                     /gene="infA"
                     /locus_tag="VQ865_000532"
     CDS             40791..41009
                     /gene="infA"
                     /locus_tag="VQ865_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HET3134944.1"
                     /translation="MAKDDVIEVEGKVVDTMPNAMFTVELENGHQILATVSGKIRKNY
                     IRILAGDRVTVEMSPYDLTRGRITYRFK"
     gene            41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ865_000533"
     CDS             41034..41150
                     /gene="rpmJ"
                     /locus_tag="VQ865_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HET3134945.1"
                     /translation="MKVRPSVKPICEYCKVIRRNGRVMVICPANPKHKQRQG"
     gene            41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ865_000534"
     CDS             41168..41533
                     /gene="rpsM"
                     /locus_tag="VQ865_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HET3134946.1"
                     /translation="MARIAGVDIPNDKRVVISLTYVYGIGLATSKKILAAAGISEDVR
                     VRDLTSDQEDAIRREVDAIKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGKAVAIAGKKK"
     gene            41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ865_000535"
     CDS             41551..41934
                     /gene="rpsK"
                     /locus_tag="VQ865_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003130556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HET3134947.1"
                     /translation="MAKPTRKRRVKKNIESGIAHIHATFNNTIVMITDVHGNAIAWSS
                     AGALGFKGSRKSTPFAAQMASEAAAKSAQEHGLKSVEVTVKGPGSGRESAIRALAAAG
                     LEVTAIRDVTPVPHNGARPPKRRRV"
     gene            41977..42912
                     /locus_tag="VQ865_000536"
     CDS             41977..42912
                     /locus_tag="VQ865_000536"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HET3134948.1"
                     /translation="MIEFEKPNITKIDENKDYGKFVIEPLERGYGTTLGNSLRRVLLA
                     SLPGAAVTSINIDGVLHEFDTVPGVREDVMQIILNIKGIAVKSYVEDEKIIELDVEGP
                     AEVTAGDILTDSDIEIVNPDHYLFTIGEGSSLKATMTVNSGRGYVPADENKKDNAPVG
                     TLAVDSIYTPVTKVNYQVEPARVGSNDGFDKLTLEILTNGTIIPEDALGLSARILTEH
                     LDLFTNLTEIAKSTEVMKEADTESDDRILDRTIEELDLSVRSYNCLKRAGINTVHDLT
                     EKSEAEMMKVRNLGRKSLEEVKLKLIDLGLGLKDK"
     gene            42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ865_000537"
     CDS             42924..43310
                     /gene="rplQ"
                     /locus_tag="VQ865_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HET3134949.1"
                     /translation="MAYRKLGRTSSQRKAMLRDLTTDLLINESIVTTEARAKEIRKTV
                     EKMITLGKRGDLHARRQAAAFVRNEIASENYDEATDKYTSTTALQKLFSEIAPRYAER
                     NGGYTRILKTEPRRGDAAPMAIIELV"
     gene            43575..43841
                     /locus_tag="VQ865_000538"
     CDS             43575..43841
                     /locus_tag="VQ865_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002905356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACT domain-containing protein"
                     /protein_id="HET3134950.1"
                     /translation="MKAIITVVGKDKSGIVAGVSGKIAELGLNIDDISQTVLDEYFTM
                     MAVVSSDEKQDFTYLRNEFEAFGQTLNVKINIQSAAIFEAMYNI"
     gene            43851..45188
                     /locus_tag="VQ865_000539"
     CDS             43851..45188
                     /locus_tag="VQ865_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018166727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PFL family protein"
                     /protein_id="HET3134951.1"
                     /translation="MDIRQVTETIAMIEEQNFDIRTITMGISLLDCIDPDINRAAEKI
                     YQKITTKAANLVAVGDEIAAELGIPIVNKRVSVTPISLIGAATDATDYVVLAKALDKA
                     AKEIGVDFIGGFSALVQKGYQKGDEILINSIPRALAETDKVCSSVNIGSTKSGINMTA
                     VADMGRIIKETANLSDMGVAKLVVFANAVEDNPFMAGAFHGVGEADVIINVGVSGPGV
                     VKRALEKVRGQSFDVVAETVKKTAFKITRIGQLVGQMASERLGVEFGIVDLSLAPTPA
                     VGDSVARVLEEMGLETVGTHGTTAALALLNDQVKKGGVMACNQVGGLSGAFIPVSEDE
                     GMIAAVQNGSLNLEKLEAMTAICSVGLDMIAIPEDTPAETIAAMIADEAAIGVINMKT
                     TAVRIIPKGREGDMIEFGGLLGTAPVMKVNGASSVDFISRGGQIPAPIHSFKN"
     gene            45432..46124
                     /locus_tag="VQ865_000540"
     CDS             45432..46124
                     /locus_tag="VQ865_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3134952.1"
                     /translation="MVKVRLYLVRHGKTMFNTIGRAQGWSDTPLTAEGERGIQELGIG
                     LRESDLQFERAYSSDSGRTIQTMGIILEELGLQGKIPYRMDKRIREWCFGSFDGAYDG
                     DLFMGIIPRIFNVDHVHQLSYAELAEGLVEVDTAGWAEGWEKLSGRIKEGFEIIAKEM
                     EDQGGGNALVVSHGMTIGTIVYLINGMHPHGLDNGSVTILEYEDGQFRVEVVGDRSYR
                     ELGREKMEEGSI"
     gene            complement(46227..47872)
                     /locus_tag="VQ865_000541"
                     /pseudo
     CDS             complement(46227..47872)
                     /locus_tag="VQ865_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520796.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
     gene            complement(47862..48485)
                     /locus_tag="VQ865_000542"
     CDS             complement(47862..48485)
                     /locus_tag="VQ865_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3134953.1"
                     /translation="MDEPLSNLEAKLRLDMRQAIREIQHEVGITTVYVTHDQEEAMAI
                     SDQIAVMKDGVIQQIGRPKELYHKPANEFVATFIGRTNIIPANLEKRSDGAYIVFSDG
                     YALRMPALDQVEEQAIHVSIRPEEFIKDESGDIEGTISDSVYLGLNTEYFIETGFASK
                     IQVSEESTFEEELQKGNRIRLRINTQKLNIFSADGSQNLIKGVNHGM"
     gene            complement(48471..48593)
                     /locus_tag="VQ865_000543"
                     /pseudo
     CDS             complement(48471..48593)
                     /locus_tag="VQ865_000543"
                     /inference="COORDINATES: protein motif:HMM:NF012235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
     gene            complement(48570..48940)
                     /locus_tag="VQ865_000544"
                     /pseudo
     CDS             complement(48570..48940)
                     /locus_tag="VQ865_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289359.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
     gene            complement(48953..49321)
                     /locus_tag="VQ865_000545"
     CDS             complement(48953..49321)
                     /locus_tag="VQ865_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3134954.1"
                     /translation="MTVGLSYEDPAVKLLNDGANIKVVYPKEGTVFLPASAAIVKKSK
                     NMENAKKFIDFIISQEVQDTLGTTTTNRPVRKNAKTSENMKPIDKIKTLTEDYDYVIK
                     NKSDIVKKYNEVFTDIQSKQ"
BASE COUNT        14870 a         9323 c        10872 g        14313 t
ORIGIN      
        1 tcctgttctt atttgatttc actatagtaa ggtgcagcag gataaagaaa aaccgagaag
       61 tttctttctc ggatttgctt attatgaggt tcctattttc tatgctccaa gagttgattg
      121 atgtgatcta cttttttagc ctctctttta tagagaatag cccagatgat gagatagaca
      181 atcgcaaact cgataatgag ctggaggtag aaaatccagt ggaaagggaa ccaaccagca
      241 agagttgcta gtgggacaaa gccagccagc ataaggaaga aatgagtcag agtggcacga
      301 agcatgctcc agtcacggct gaataagcgg ttgccaaagt tgaagagcat accgatggct
      361 gcccagataa gtgtgcagta gagcaagacc agggcaccgt gaacctgatg ctgatccatc
      421 acttggccga tgagagagta gggatttagt ggtgcgtagg tatttggtgc ataaatgagt
      481 gaaaagagga tggagaggat gaggccgata agaacaccgg cagctgcatc gtgaaatact
      541 tgttttttca tagttctaat ttctccttga tggtttttag ataacggcgt gaagagtagg
      601 tgaagctttc gtttttcaag aaaatttcta ccagaccgtt tggcgtgagc ttgaggtgag
      661 agatggaatc gatattgatg atttctgatt gggaaatttg gataaaattg gttggcaaga
      721 gtttaagaac ctgatagagt cgcaaatcaa tgctgtaggt ctgactcgcg gtttctgcta
      781 gaaccttccg attctcgata tagaagcgct gaatcttgcc aatctcaact agatagacct
      841 gatcatcgat tttccctttg attttttctc tttggtccag attttctgcg aactcgatga
      901 ctttctggac tttatctgtc ggctgaggtg cttggacaat cagcttttcc tcctcgtaag
      961 tctcactaat ctgtagttct actttcatag ttttctctcc ttttcagtta tacaaggttg
     1021 tgatcacttc ctgtatatcc ttattaaaca ctattttata gcccatggca aggaaccttg
     1081 tctatgtgga gggattgggc tcctatgtgg tggagctttt ctgttctttc tgaaatatgg
     1141 tataatagca ctaattaatt tctaggaaaa tagatacaga aaggggctga aagatgtctc
     1201 atattattga attgccagag atgctggcaa accaaatcgc agctggggag gtcattgaac
     1261 gtcctgccag tgtggttaaa gagttggtag aaaatgccat tgacgcgggc tctagtcaga
     1321 ttatcattga gattgaggaa gctggtctca agaaggttca aatcacggat aacggtcatg
     1381 gaattgccca cgatgaggtg gagttggccc tgcgtcgcca tgcgaccagt aagataaaaa
     1441 atcaagcaga tctctttcgg attcggacgc ttggttttcg tggtgaagcc ttgccttcta
     1501 ttgcgtctgt tagtgtcttg actctgttaa cggcggtgga tggtgctagt catggaacca
     1561 agttagtcgc gcgtgggggt gaagttgagg aagtcatccc agcgactagt cctgtgggaa
     1621 ccaaggtttg tgtggaggat ctctttttca acacgcctgc ccgtctcaag tatatgaaga
     1681 gccagcaagc ggagttgtct catatcattg atattgtcaa ccgtctgggc ttggcccatc
     1741 ctgagatttc ttttagcttg attagtgatg gcaaggaaat gacgcggaca gcagggactg
     1801 gtcaattgcg ccaagcaatc gcagggattt acggtttggt cagtgccaag aagatgattg
     1861 aaattgagaa ctctgaccta gatttcgaaa tttcaggttt tgtgtccttg cctgagttga
     1921 ctcgggctaa ccgcaattat atcagcctct tcatcaatgg tcgttatatc aagaacttcc
     1981 tgctcaatcg tgctattttg gatggtttcg gaagcaagct tatggttgga cgttttccac
     2041 tggctgtcat tcacatccat atcgaccctt atctagcgga tgtcaatgtg catccaacta
     2101 agcaagaggt gcggatttcc aaggaaaaag aactgatgac cctggtttca gaagctattg
     2161 caaatagtct caaggaacaa accttgattc cagatgcctt ggaaaatctt gccaaatcga
     2221 ccgtgcgcaa tcgtgagaag gtggatcaaa ctattctccc actcaaagaa aatacgctct
     2281 actatgagaa aactgagccg tcaagaccta gtcaaactga agtagctgat tatcaggtag
     2341 aattgactga tgaagggcag gatttgaccc tgtttgccaa ggaaaccttg gaccgattga
     2401 ccaagccagc aaaactgcat tttgcagaga gaaagcctgc taactacgac cagctagacc
     2461 atccagagtt agatcttgct agcatcgata aggcttatga caaactggag cgagaagaag
     2521 catccagctt cccagagttg gagtttttcg gacaaatgca cgggacttat ctctttgccc
     2581 aagggcgaga tggactttac atcatagatc agcacgctgc tcaggaacgg gtcaagtacg
     2641 aggagtaccg tgaaagcatt ggcaatgttg accagagcca gcagcaactc ctagtgccct
     2701 atatctttga atttcctgcg gatgatgccc tgcgtctcaa ggaaagaatg cctctcttag
     2761 aggaagtggg cgtctttcta gcagagtacg gagaaaatca atttattcta cgtgaacatc
     2821 ctatttggat ggcagaagaa gagattgaat caggcatcta tgagatgtgc gacatgctcc
     2881 ttttgaccaa ggaagtttct atcaagaaat accgagcaga gttggctatc atgatgtctt
     2941 gcaagcgatc tatcaaggcc aatcatcgta ttgatgatca ttcagctaga caactcctct
     3001 atcagctttc tcaatgtgac aatccctata actgtcctca cggacgtcct gttttggtgc
     3061 attttaccaa gtcggatatg gaaaagatgt tccgacgtat tcaggaaaat cacaccagtc
     3121 tccgtgagtt ggggaaatat taaaagtata aaaaagtctg ggaaaaattt tcaaaatcag
     3181 aaaaacgcat aaaatcaggt gttcaaaaac cttgatttta tgcgttttat catggaaata
     3241 gttacttcat gttttcctaa ttcttttcga aactcttttt aaaccacgtc agttttatca
     3301 gtaatctcaa aacagtgttt tgagctaatt ttgccagttt tgtctgtaac atcgaagttg
     3361 tgtttgacca ctctgcgact ggtttcctag tttgctctat gattttcaca gagtattaaa
     3421 ttgcgatttt gccaagtttc tttattcgtc taaaagtaga gtctgttcta tgcgtctaat
     3481 gtacgaatta ggttgaccat ttcaatagct ccttgtgcac actcagaacc cttatttcct
     3541 gctttagtgc cagctcgttc tatggcttgt tcaattgtat ctgtcgttag cacaccaaac
     3601 ataacaggaa tttcgctatt taaactgatt tgggcgattc ccttagatac ctcgctacat
     3661 acataatcat aatgacttgt attccctcta atgacagctc ccaagcagat aattgcatca
     3721 tattttttac tttttgccat ttttgatgca atcagtggta tttcaaaagc tcctggaacc
     3781 caggctacct ctatatcttt ctcgtttaca ttctctcttt tgagattatc tagtgctcca
     3841 gataataatt ttgaagttat aaattcatta aatctcgcta caacaatacc tattttaata
     3901 ttgtttgcta ctaaattacc ttcataagtg ttcatttatt tttcctccat atttaaaatg
     3961 tgacccattc gatttttctt tgtttctaaa taaaaactat cgtaaggatt ggcttctatt
     4021 tcgattgata ttctactgga aatggtaatt ccatattttt ctaactgttc aaccttgtca
     4081 ggattatttg tcagtaaatg aagtgactga agtcccagat ctttaagcat ttgtgctcca
     4141 atatgatatt ctcttaaatc accttcaaag cctaatgcaa gattggcatc aagcgtatcc
     4201 atgccttgat cttgtaaatg ataggctttt aatttattga taagtccaat tcctcgtccc
     4261 tcctgtcgca agtaaagtaa gacacccgaa ccattctcaa caatcatttt catagcttta
     4321 tcgaattgct gtccacaatc gcaacgtaaa gagcctaaaa catctcctgt taaacattcg
     4381 gagtggaccc gacataatac attggcttca tcctctatgt ttcccataat aagagcaaga
     4441 tgatgttccc catttagttt atctatatag ctaattgctt tgaaattacc gtatctagta
     4501 ggcatattga cagttgaaac tcgttctacc agctgatcat atacttttct atattcttgt
     4561 aattctttga tggtaattag tggaatgttg tgtttcttcg agaactgaat taaatcatct
     4621 gttctcatca ttttgccatc atgattcatt atttcacaac ataggccaca ctcttttagt
     4681 ccagctaatt ttaataaatc aacagttgct tctgtgtgtc catttctttc tagaacacca
     4741 cctttttttg caattaaagg aaacatgtgt cctggcctgc gaaaatcaga gggtgttata
     4801 tcttcagcta cacacatacg tgcggtcagt cctctttcct cggcagaaat acctgtggtc
     4861 gtttctttat aatcaattga aactgtaaaa gcagtcttat gattatctgt attgttttca
     4921 accataggtg aaagcattaa ttgattagct aaactttcgc tcataggcat acaaattaat
     4981 cctttggcat aagtagccat aaaattaaca ttttctgttg tagctgcttg tgcagaacaa
     5041 attaagtctc cttcattttc tctatccttg tcgtctataa caagaacaag tcgtcccttc
     5101 tgcaatgctt ctaatgcttc ttgtattttt cgatattcca ttgactgatt atcctttctg
     5161 ctaaaatcca ttttgatata atagttcctt agatatttct gattttggag agttatccat
     5221 cagtttttgc acatatttac ctaagatatc attttcaaga tttactgtac tcccgacttg
     5281 tttactctta agaatggttt gttccaaggt atgagggata acagatactg aaaagtttac
     5341 tttggagact ttagcgacag tcagactaat gccgtcaatt gtaatagatc ctttttcaac
     5401 tattaaatct aaaatttctt tttgtgtgtt gatttgatac catacagcat tatcatcttt
     5461 ttttattgac gagatttttc ctgtaccatc aatgtgtcct gtaacgacgt gacccccaag
     5521 tcgaccgttg acagataagg ctctttctag attcacctca cttccatgtt ttaatagagt
     5581 aagagctgtt cgactccatg tttcattcat tacatcaact gtaaaggatt gatgattgaa
     5641 atgagtaact gtaagacaga taccatttac tgctatacta tcgcctaaat ggatatccgt
     5701 taatattttt gaggctttaa ttgatagttt acaattacga gagtctttct gtattctttc
     5761 aacttttccg atttcttcaa ttattcctgt gaacatggat aaatcacttc actttctatg
     5821 agatagtcat ttcctatttg agaaaatgca taaggtttca atctaatagc gtcatttggc
     5881 aaagaaatgc cttcacctcc gacaggaaac ttggcactgc ctccaaaaat ttttggtgca
     5941 atatatattt tcagctcatc aacaatttgt tgttccaaag cactccaatt cattagactg
     6001 cccccttcta gaactaggct atcaatctgc atgtttccta gatgttgcat taaactcgat
     6061 aagtctatat gattgccttt tttctttatg gaaagtattt cacagccatg attttgatat
     6121 agcttcattt tatttttgtc ttcagaggaa gtggcaatgt aagttttaat atcatttgct
     6181 gtttttacga ttttagaggt aagaggagtt cgtaaatgtg tatcgcatat gatacggata
     6241 ggatttttcc cttcctccaa tctacatgtc agcaaaggat cgtcttgaat aacagtattg
     6301 actcccacca taattgcact aacatggtgt cgtaactgat gcacatgctt tcttgcttct
     6361 tcttcagtaa tccatttgga ttgatttgtt ttagtggcta tttttccatc cattgacatt
     6421 gcatatttca taaaaacata gggtacatgc tgggtaatat actttctaaa actttttatt
     6481 aagttaagac actcattttc taaaattcca acagtaactt gaagattatt ttcctcaagt
     6541 atctttactc cttttccaga tacaatagga ttacagtcta ggcttccaat gactactctt
     6601 gtaataccac tatcgattat agcatctata cagggaggtg ttttcccgaa gtgacaacag
     6661 ggttcaagtg ttacataaag cgtcgctccg acaggggatt ttctacagtt tttaagagca
     6721 tttctctcag catgtgggcc accaaaaaac tcatgataac cttgtccgat aatgtgatta
     6781 tcttttacaa taattgcgcc aaccatagga ttgggattga cgtaaccagc ccctttttgt
     6841 gccagtttta ttgctaattt catatatttt gaatcgctca tctcactacc tccaaaaaaa
     6901 tataccttga ataggggact actcaaggca tacaaaagaa aacttatgcg attaacaaaa
     6961 atgctctgaa atgacaagta atcatttcag agcacgcaaa aagcacaaat atacttttat
     7021 cttctttcat ccagactata ctgtcggctt tggaatttca ccaaatcatg cctttcggct
     7081 cgtgggctat accaccggta gggaattgca ccctgccctg aagatagtta ttcaattaca
     7141 gatgattata gtacttaatt ttgaatatgt caacagataa atacagattg tttttgatat
     7201 actgtatttg tgataatcga ttctcgctcc tcggataaag aaaatatgat atactagata
     7261 aacgaaataa gagagaagga acactatgta cgcatattta aaaggaatca ttaccaaaat
     7321 tactgccaaa tacattgttc ttgaaaccaa tggtattggt tatatcctgc atgtggccaa
     7381 tccttatgcc tattcaggtc aggttaatca ggaggatcag atttatgtgc atcaggttgt
     7441 gcgtgaggac gcccatttgc tttatggatt tcgctcagag gatgagaaaa agctctttct
     7501 tagtctgatt tcggtctctg ggattggtcc tgtatcagct cttgctatta tcgctgctga
     7561 tgacaatgct ggcttggttc aagccattga aaccaagaac atcacctact tgaccaagtt
     7621 ccctaaaatt ggcaagaaaa cagcccagca gatggtgctg gacttggaag gcaaggtagt
     7681 agttgcagga gatgaccttc ctgccaaggt cgcagtacaa gcaagtgctg aaaaccaaga
     7741 attggaagaa gctatggaag ccatgttggc tctgggctac aaggcaacag agctcaagaa
     7801 aatcaagaaa ttctttgaag gaacgacaga tacagctgag aactatatca agtcggccct
     7861 taaaatgttg gtcaaatagg agcagagaat gacaaaacgt tgttcgtggg tcaagatgac
     7921 caacccgctc tacatcgcct atcatgatga ggagtggggt cagcccctcc atgatgacca
     7981 agcattgttt gagttgttgt gtatggaaac ctatcaggca ggcctgtctt gggaaacggt
     8041 actcaacaaa cgccaagctt tccgagaagc ctttcatagc tatcaaattc actcagtcgc
     8101 agagatgact gacactgaat tggaagccat gctggagaat ccagctatca ttcgaaatag
     8161 agccaagatt tttgctacac gcgctaacgc ccaagccttt ctacagttac aggcagagta
     8221 cggctctttt gatgcctatc tttggtcttt tgttgagggg aaaactgtcg ttaacgatgt
     8281 tcctgattat cgccaagccc cagctaaaac acccttatct gagaaattag ccaaagatct
     8341 caaaaaacga ggcttcaagt tcacaggccc agtcgccgta ttgtcttttc tacaggctgc
     8401 agggctagtt gatgaccacg agaatgattg tgagtggaaa ggtcttaaat gatgtctaac
     8461 aaaaataagg gaattctgat ttttgcgatt ctctatacaa tcctctttgt gtttgatggc
     8521 gttaaattgc tggcttcttt aatgccatct gtcattgcaa attatcttgt ttatgtagtt
     8581 ttagctttat atggctcctt cttgttcaag gatagattga tccaacaatg gaaggagatt
     8641 agaaagacta aaagaaaatt cttctttggc gtcttaacag gatggctctt tctcattctg
     8701 atgactgttg tctttgaatt tgtatcagag atgttgaagc agtttgtggg attagatgga
     8761 caaggtctaa atcagtctaa tattcaaagt acctttcaag aacaaccact actgatagct
     8821 gtttttgctt gtgtcattgg acctctggta gaagaattat ttttccgtca ggtcttattg
     8881 cattacttgc aggaacggtt gccaggttta ctaagcatta ttctggtagg acttgttttt
     8941 gctctgactc atatgcacag tttggctcta tcagagtgga ttggtgcagt tggttactta
     9001 ggtggaggcc ttgccttttc tattatttat gtgaaagaaa aagagaatat ctactatccc
     9061 ctacttgttc acatgttaag caacagcctc tccttaatca ttttagctat cagtatagta
     9121 aaatgaaatg agaacaggac aaatcgattt ctaacaatgt tttagaagta gaggtgtact
     9181 attctagttt caatatactg taatatgtga tgaaaatgcc agtaatgata ccgagaaaaa
     9241 agctgagaaa cttttcccag ctttatttgt tatagtcaaa gagaatgact tgttcctgtg
     9301 catctacatg agcatggacc ccaaagggta caattgctct tggagttgcg tggccgacat
     9361 tcagattata gacaatcggg atattgctgt caatgatatc caatagtgcc tctttatagt
     9421 cgtcatggaa agtttcatcc ataggttttc cgaccaagag tccattgatg accgcgaata
     9481 tgccagtgtc ctttaaagtt agcaacattt ttttgaagtc ttctggctta ggcttttctt
     9541 cgcttgtttc gagcaagagg attttccctt cccagtctga caagtcaggg aaaagtttgt
     9601 atttttggca gagttccgtg ctatctgcgt atcgagagtt gtcaaagata tcgtagaggg
     9661 attcgaggca accaccgagg attttcccct cgaactgagc acttccttgc aacaagtcaa
     9721 aacctgtatt tgtatgactg acacgaggtg ttcccagggc cgtgggacta aaatcagttc
     9781 gttcctcata ccaaacgtca ctagggcgga tttctgaaat tcttcccgtc ttaatcaatt
     9841 ctttaaagta gtgaaggcta taggctagca tttctttgtc taattcacaa atgtctgcta
     9901 aaaaggattg accataaaaa gtcttgattc ctaatttatg caacatgagg tggttcatgg
     9961 ttgtatccga gaagccaaga aaaatttttt gcttgataac cttttggagt tggtcatttt
    10021 caaaaagata aggtagcaag cgataggtat cgtctccacc gatggcacat aggatcatgt
    10081 cgatgctatc atcagaaaag gcatgaatca aatcctctgc acgagcttca ggatggtcct
    10141 tgataaagtc taatcctttt aacgaatggg acaaaaagat gggattgagt cccagatcct
    10201 tgagacgttg gatacccaag tccacttcgt gtttgacaaa atcctctccg ataatgccac
    10261 tagataaact aacaatacca atagtagaaa ccatatctca tcctcctaga aatagattga
    10321 gcctatttta tcacaaaata taagagaaag ctatgtggga tttcagaaga atacttttaa
    10381 tactcttcga aaatctcttc aaaccacgtc agttttatct gcaacctcaa agctgtgctt
    10441 tgagcaacct gcagctagct tcctagtttg ctctttgatt ttcattgaat ataactcaaa
    10501 aaagtaagtg aaaaagcaac cgcacctgca gttgctttta tcgttttctt attcttgata
    10561 gcgtgttggt cctgcacttg cactacggat attcaagcgt ttcttgagat agaagcgaag
    10621 ggctaggagg gctgctccaa taatagctag tggcaatgga tccagtactg ggttaaggct
    10681 agctggtagg aagcttgttg caaagaagac aagcaaccaa aggaacatag aagctaggat
    10741 aactagtaca gatttccaga aaggtggacg ttgactgcga tccatatctg atccatagta
    10801 ttggtaaaca aagtagtaca tcaagtagaa ggcaaatcca ccaaccagtc caactaatag
    10861 aagagtaatc aatccatagc cgaaagcttg gtctgccgca aagaaggttg tgagggcgct
    10921 gacaagggca aagaggctag tgatgaaaag agctgagtcc ataatcatca gttttgggtc
    10981 atcattttct tttggatgct ctttttcgta ctgctctttg acagtgaagc tatgagccca
    11041 atgagttggt gcgccgtata gggaacgggc agttgtacct ttagattgct cctcaaggat
    11101 ttggggaatg acttcctcaa aaatagtctg gatttcagcg tctgttttcc catctttgat
    11161 gaattgttgg gtagcaatgt ggacaaactc ttggtttttc ttagttaatt tttgtagatc
    11221 aatttgagac ataggaactc ctcttagaac cattttttat ggatgagata gagagtgagc
    11281 gagacactca tagcaaaggc gataaagacg attaaccaga aggcatttgg ctctccgttt
    11341 agggggattt cattatcctt aaagttcatc ccgtaggcag aaaagaccat ggttgggatg
    11401 gacatgacga tggtcacaag ggccaaggtt ttcatgatgt tgttctggtt gttagaaatg
    11461 atagaggcaa aggtctctgt catagaatgc aagacgtttc cataaatatc tgccatctcg
    11521 atggcctgtt gggtttcaat cagggtgtct tcaagcaggt cttcgtcctc aaggtatttc
    11581 ttgatattgc tggttgaact ggtcaatttc ttaatcacgc gctcatttgt tttgagggag
    11641 gccttgaaat agacgatagt tttttccaat tccatgagct caatcaattc ttcattacga
    11701 gttgattgat gcagttgact ttcgatttgt tcactcttgc ggtcgattga acgaagggct
    11761 gttaggtaaa gctctgcatt gcgataaaga atttgaaaga taaaacgtga acgcatgaag
    11821 gtatagaaat tacgcaatcg acggttgata aagacatcaa ggacaggtag tggttccaaa
    11881 cacgtagtga taatggtttc ctcagtgatg ataataccaa gcgggatggt tacgtagtag
    11941 gtgcggttat ttctttcctc cgtgaccggc acgtctacga taatcagggt atactcgtct
    12001 tcaatggtaa tacgagacat ttcttccgca tcgagcggtg ctcgaaggtc ggcaatatca
    12061 atatcgaagg tgttggcgat ttcgagtgat tcattttgag tcggattgac gagattgatc
    12121 caagtacccg gttcaagcgt atcgatctct ttaaattcag ttgttgtaga gagaaaaact
    12181 tgtttcatat cccttatcct ttctcatttt tcagattttt tcacactgta ctattatact
    12241 acaaaatcgg ccttttgggt aatagaatct cacttttttt ggtataatgg taagcaataa
    12301 tggactagaa agaacaaaga tgcaagataa aattgtcatt catggggcgc gtgcccataa
    12361 tttaaaaaat attgatgtgg agattccgcg agacaagttg gttgtcgtga ctggcttgtc
    12421 aggttcaggg aagtccagtc tggcttttga tactctctat gcggagggac aacgtcgcta
    12481 tgtagagagt ttgtccgcct acgctcgtca gttcttggga aatatggaaa aaccagatgt
    12541 agatgccatt gatggtctca gcccagctat ttccatcgac cagaaaacga ctagtaaaaa
    12601 tcctcgctcg acggtgggaa cgacgactga aatcaatgac tatctgcgtc tcctctacgc
    12661 acgtgtgggg acgccttact gtatcaacgg acatggagct atcaatgctt cttctgtgga
    12721 gcaaatcgtt gataaggttt tggagttacc tgaacgccag cgcttgcaga tcttggctcc
    12781 tgtcatccgc aagaaaaaag gccaacataa gagtgttatc gagaaggttc agaaagacgg
    12841 gtatgttcgt gtccgtgtgg atggggaagt ctatgatgtg accgaagtgc cagagttgtc
    12901 taagagcaag caacacaata tcgatgtcgt ggttgaccgt attgttatca aggagggcat
    12961 tcgtagtcgt ctctttgatt ccattgaggc tgcccttcgt attgcagaag gttatgtcat
    13021 tatcgacacc atggacgact cggagttgct cttctctgag cattatgcct gtccagtttg
    13081 tggatttact gtcccagagt tagaacctcg tctcttctct ttcaatgctc cctttggctc
    13141 ttgtagtgag tgtgacggct tggggattaa gctggaggtg gatactgatt tggtagtgcc
    13201 agatgccagc aaaaccttac atgagggagc gctggcacct tggaatccta tctcatccaa
    13261 ctactatcca aacatgttag agcaggccat gaaagtcttt ggagtggcta tggataagcc
    13321 ttttgaggac ctgtcagaag aagataagaa cttgattctc tacggctcag atggtaagga
    13381 attccatttc cattatgaaa atgaatttgg tggtgtgcgc gatatcgaca ttccgtttga
    13441 gggagttatc aataatatca aacgtcgtta ccatgaaacc aatagcgatt acactcgcac
    13501 tcagatgcgt ctctacatga atgagctgac ctgcggaacc tgtcaaggct atcgtctcaa
    13561 tgaccaggcc ttgtctgtcc gtgtgggcgg ccagcaaggg ccacatattg gagaaatctc
    13621 agacctgtct atcgctgacc acttggactt ggtgagccag ttaactttgt ctgaaaatga
    13681 agccatcatt gctcgtccca ttctcaagga aatcaaggat cgtttgacct tccttaataa
    13741 tgtgggtctt aactatctaa ccctgtcacg ttcagcagga accctttcag gtggggaaag
    13801 tcagcgcatt cgtttggcaa cccagattgg ttccaaccta tcaggtgtcc tctatatcct
    13861 agacgagccg tcaatcggtc ttcaccagag ggacaatgac cgcctgattg ccagtctgaa
    13921 aaagatgcgt gacttgggca atactcttat cgtggtggaa cacgacgaag ataccatgcg
    13981 tgaagctgat tatctgattg acgttggtcc tggtgccggt gtttttggtg gtgagattgt
    14041 tgcagcaggt acacctaagc aagtggctcg caacagcaag tctatcacag gtcagtactt
    14101 gtcaggcaaa cgtgtcatcc cagtaccaga agagcgccgt gtcggaaatg gtcgttttat
    14161 tgaagtgaca ggagcgcgtg agaacaactt gcaaaatgtc acggctcgct ttccactagg
    14221 aaaatttatc gcagtgacag gtgtgtcggg ttcagggaaa tcgactctaa tcaacagcat
    14281 tctcaaaaaa gccattgccc agaagctcaa ccgtaattca gacaaacctg gtaagtttaa
    14341 gactattaca gggattgagc atgtcgaccg tttgattgat attaaccaga gccctatcgg
    14401 acggacgccg aggtctaacc cagctaccta tacaggagtt tttgacgata tacgtgacct
    14461 ttttgctcag acaaatgaag ccaagattcg aggctacaag aaggggcgct tcagtttcaa
    14521 cgtcaaggga ggtcgctgtg aagcttgctc aggtgacggg attatcaaga ttgagatgca
    14581 cttcttgcca gatgtttatg tggcttgtga agtttgccac ggaacccgct ataacagtga
    14641 aaccctagaa gttcactaca aggaaaagaa tatttcgcag gtcttggata tgacggtcaa
    14701 cgatgcggta gaatttttcc aacacattcc gaaaattcaa cgcaaactcc agaccatcaa
    14761 ggatgtaggt ctaggctatg tgaccttggg acagccagct accacccttt ctgggggaga
    14821 agcccaacgt atgaagttag ctagcgaact ccacaaacgc tcgacaggaa aatctttcta
    14881 cattctggat gagccgacga cagggcttca tacagaggac attgctcgcc tgctcaaggt
    14941 tttagctcgc tttgtagacg ccggcaatac agtcctcgtc atcgagcaca atctggatgt
    15001 tatcaagacg gcagaccata tcattgactt gggacctgag ggcggtgtcg gtggtggaac
    15061 catcatcgta acaggaactc cagaagaagt agctgccaac gaagccagct atacaggaca
    15121 ctatttgaaa ggaaagttac atcatgaata aacgcgtaca agcatttcta gctaaaatgc
    15181 aagaaaaaga actagatggt atcatcatca acaatcttaa aaacgtctat tatttgactg
    15241 gtttttgggg ctcaaacgga acagtcttta tcagccgtga ccgtcaggtc ttagtgacag
    15301 actctcgcta tatcatcgca gctaagcaag aaaccagtgg ttttgagatt gtggctgatc
    15361 gtgatgaatt ggctgtcatt gcaggaattg ttaaggacat gaacttgact cgtatcggtt
    15421 ttgaagatga gatttcagtg tcttattacc accgtatgca ggcagctttt gcaggtttga
    15481 acttgcttcc acaaactcag tttgtggaag gtcttcgtat gattaaggat gaggcagaga
    15541 ttgcagcgat tcgcaaggct tgttctatct cagaccaagc tttccgcgat gcgcttgact
    15601 ttatcaaacc aggaaaaact gaaattgaga ttgccaactt ccttgatttc cgcatgcgtg
    15661 agttgggagc atctggctta tcttttgata cgatcctagc tagcggtatc aattcttcta
    15721 aaccccatgc ccatccaatg cacaaaccag tggagttggg agaagccatc accatggact
    15781 tcggctgtct ctatgaccac tatgtcagtg atatgacccg gactatctat ctagggcatg
    15841 ttagcgatga gcaggcagag atttacaata cggttctaaa agctaaccaa gccttgattg
    15901 accaagctaa ggcaggctta ggtttccgtg actttgacaa aatccctcgt gatattatca
    15961 ttgaggcagg ttatggtgac tactttactc acggcattgg ccacggtatt ggtctggata
    16021 tccatgagga accctacttt agtcagactt ctacagaaac tattaagaca ggtatggcct
    16081 tgaccgatga accaggtatc tatatcgaag gcaaatatgg cgttcgtatc gaggatgata
    16141 tcctgattac agagacaggt tgtgaattat tgaccctagc tccaaaagag ttgatagtca
    16201 tttagttgtt tgtcaagaaa aaagtacgaa aatgacgaaa aaagtcaaaa aaaattaaaa
    16261 ataggtcgca agtcggatgt tttttatggt ataatagact aaactgatag taacatgtag
    16321 cgaaaggggt aggtacatga ttaaaattta tacagtctca agttgtacta gctgtaaaaa
    16381 agcaaaaacc tggctcaatg cccaccagtt aagttataaa gaacaaaacc ttggtaaaga
    16441 aggaattacg agagaagaat tactggatat tctaaccaaa acagataacg gaatagccag
    16501 catcgtttcg tctaaaaatc gctatgccaa agcccttgga gtggatattg aagatttgag
    16561 tgtcaatgaa gttctcaatc tgattatgga aacaccgaga attttaaaga gcccaatcct
    16621 tgtagatgaa aaacgcctgc aagttggcta caaggaagac gatattcgtg ccttcctacc
    16681 acgatctgtc cgtaatgtag aaaatgcaga agcacgtttg cgtgcagctc tataaacatc
    16741 aaggctggga gcacttccca gtcttattct attttaattt caaaaagaaa gaagaaagaa
    16801 atgaaaaaaa tagttcttgt tagtctagct ttcctttttg tcctggttgg ttgcggacag
    16861 aaaaaagaaa ctggaccagc tacaaaaaca gaaaaagata cgcttcagtc ggcattgcca
    16921 gttattgaaa atgctgagaa gaatacagtt gtaactaaga ctttggtctt gcccaagtca
    16981 gatgatggta gccagcagac acaaacaatt acttacaaag acaagacttt tttgagtcta
    17041 gctatccaac aaaaacgtcc agtctctgat gagttgaaga cttatattga ccaacatgga
    17101 gtggaggaaa ctcaaaaagc tcttcttgaa gcggaggaga aggataagtc tatcattgaa
    17161 gctcgtaaat tggcaggttt caaacttgaa acaaaactat tgagcgcaac ggaacttcaa
    17221 acaacgacta gttttgattt tcaagttctg gatgtcaaga aggcttccca gttggaacat
    17281 ctgaagaata ttggtttgga aaatcttttg aaaaatgaac caagcaaata tatttcagat
    17341 agattggcaa atggcgcgac agaacaatag aaaatccaaa taaatagact gcctgaattg
    17401 tagaaggtaa ggaattatgc tataatggta ctattctaag gaaagagggt gttagaatgg
    17461 gatttactga agaaacagta cgttttaaat tggacgattc caataaaaaa gaaattagcg
    17521 aaactttgac agatgtttat gcttcgttga acgataaggg ttacaaccca attaaccaaa
    17581 tcgtaggtta cgtattgagt ggagaccctg cctacgttcc tcgttataat aatgcacgaa
    17641 atcaaatccg taagtatgag cgtgatgaaa tcgttgagga attggttcgc tactacctca
    17701 aaggacaagg agtcgatcta taacctatga gaattatggg attggacgtc ggttcaaaaa
    17761 cggtaggggt ggcgattagc gatccgcttg gttttacagc tcaagggctt gaaatcatcc
    17821 agataaatga agaacaaggc caatttggtt ttgaccgcgt taaggaattg gttgatactt
    17881 acaaggtgga acgatttgta gtgggcttgc ctaaaaacat gaacaataca agtggaccgc
    17941 gcgtagaagc tagtcaagcc tacggagcaa agctagaaga gttttttggt ttaccagtag
    18001 actatcagga tgaacgcttg acaacagtgg ctgctgagcg catgttgatt gaacaagcag
    18061 atatcagtcg caataagcgc aagaaagtca ttgataagtt agcagctcag ctgattttac
    18121 aaaattattt agatagaaaa ttttaatata aaggagaggc tatgtcacac gatcataacc
    18181 acgaccacga agaacgtgaa ctaatcacac tagtagatga gcaaggaaat gaaaccttgt
    18241 ttgaaatcct tttgacaatt gatggaaaag aagaatttgg taaaaactat gttcttctag
    18301 taccagttaa cgcagaagaa gacgaagacg gacaagttga aatccaagct tactcattca
    18361 ttgaaaatga agatggaaca gaaggcgaat tgcaaccaat cccagaagac tcagaagacg
    18421 aatggaacat gattgaagaa gtcttcaaca gctttatgga ggagtaaaaa cgtccggggg
    18481 acgtttttag ccctgcgcta gaaattagaa acgcaggtag tctgggagac tgtatcagcc
    18541 caactccaga aatggggaag agttggaacg tccagtgaac atttttaccc caactcttag
    18601 aaattgagaa gagttggaac atctagtgga tgtttttagc ccatattcac attcatagta
    18661 gctagttatt agctaaccag gtaagaggtc gggacgaaaa tcctggcctt gtttttatta
    18721 gtaaccatac tttaatgcga taattgattg gacttttgtc aaggagatgt gtatgtttga
    18781 agtagaagaa tggctccata gtcggattgg tttgaatttt cgatcaggtt tgggccgaat
    18841 gcagcaagcg gtggatttgt taggaaatcc tgagcagtct taccctatta tccacgtaac
    18901 agggactaat gggaaaggat ctaccattgc ttttatgagg gaattattta tggggcatgg
    18961 caaaaaagtt gcgaccttta cctcccctca tatcgtatcc atcaatgacc gaatctgcat
    19021 taatgggcaa cctatagcag acgcagactt tatccgtttg gctgatcagg taaaggagat
    19081 ggagaaaacg cttctgcaaa ctcctgacca gttgtccttt tttgaattgc tgaccttggt
    19141 tgcttttctt tattttaggg agcaggaggt ggatttggtt ttattagaag tgggaattgg
    19201 tggcttactt gacacgacca atgtggtaac tggagagctt gctgtcatca cctccattgg
    19261 gcttgaccat caagaaacct tgggtgatag tctagaagca attgcagagc agaaagctgg
    19321 tattttcaag gctggtaaaa aggcagtgat tgcgaaattg cctccagaag ctagacttgt
    19381 ctgtcagaaa aaagccgaat ctttagctgt tgacctttat caggcaggtc aagatttttc
    19441 agtgctgaat ggtgattttt caagctcttt actaaatctt tcacagctga acataggctt
    19501 agaaggagcc tatcagcagg agaatgcggc cttggcgttg caaacttttc ttctttttat
    19561 gggagaaaga aaggaagcta ttgatgaaca ggctgtaaga aaggccttgg aacagaccca
    19621 ttgggctggt cgcttggagc gtattcgccc acagatttac ttggatggtg ctcataacct
    19681 ccctgccttg actcgcttgg ttgagtttat caaagaaaaa gagcaggaag gctatcgacc
    19741 tcaaatcctc tttggatcct tgaaacgtaa ggattatcaa gggatgttgg gttatctgac
    19801 tgaaaattta cctcaagtgg aactcaaaat gaccggcttt gactatcaag ggtctttgga
    19861 cgagacagat gtaacaggtt accatgtaat tccctcttac cgagaattta tcagcagttt
    19921 cgaagaaagg gcagacgctc aagacttgct gttcgttaca gggtctctct attttatctc
    19981 agaagtacgg ggctacctgc tggaccgtga gcagataaat tgaccccctt ttttgaactt
    20041 gttatactag gggaattgct ggttagagaa aatttctcta aattggtagc agaaaggaaa
    20101 ttcatcatga aattaaaaag attcacactt tctcttgctt ctctagcaag ttttagtctc
    20161 ttagtagctt gttcacaaag agctcaacag gttcaacagc ctgttgctca gcaggtccaa
    20221 cagcctgctc aacagaatac caatactgca aatgcaggag gtaaccaaaa tcaagcggct
    20281 ccagtacaaa accaacctgt tgctcaaccg accgatattg atgggactta tactggtcag
    20341 gatgacggag accgtatcac tttagtggta actggaacga ctggtacatg gactgagctc
    20401 gaatctgacg gggatcagaa agtcaaacag gttacatttg attcagcaaa tcaacgcatg
    20461 attattggcg atgatgtcaa aatttacact gtaaacggta atcaaatcgt cgtagatgat
    20521 atggatagag acccatcgga ccaaatcgtt ttaactaaat aagactatgc aagtagaaag
    20581 ggctggattt ttcagccttt ttacttttac ctagaaaata atcataaata cttgccttct
    20641 accgaatacc tgcgttatac tagtatcaat tacttgtttt tagcattcaa actatcaagg
    20701 aggggatatg aaatatagga aatttcaatt attgatgtcc aagtatggct ttagtctttc
    20761 gattatgcta cttgaacttt gtcttgtttt tggtctcttt ctttatttag gacgcatggc
    20821 tcccatttta tggattactg tcctcattct actgagtatc atcacaatca tttcgatagt
    20881 caaccgtaat acgactcctg agaataaggt aacctggttg ttagtagcct ttgtgccagt
    20941 atttggtccc ttgctctatc tgatgtttgg tgaaaggcga ttgtccaaaa aagaaatcaa
    21001 acaactgaag aagctaggct ctatgcattt ccaagaagca aatagccagc tactaaaaga
    21061 gaaattaaaa gaaagtgaca aggcagctta tggagtcatc aagtccttat tgagtatgga
    21121 taccaatgct gacatctatg atcaaactgc ctctacattt tttcctaacg gagaagctat
    21181 gtggaaaaag atggtagaag atcttaaaaa ggctgagaaa tttattttct tggaatatta
    21241 cattatagaa gaaggtttga tgtggaatcg catactagat atactagagc aaaaggtagc
    21301 tcagggtgta gaggttaaga tgctctatga tgatatcggc tgtatggcta ctttaacagg
    21361 agattatgca catcgacttc gtcagctggg catcgaggcc cataaattca ataaagttat
    21421 tcctcgtttg acagtggctt ataataacag agatcataga aaaatattga ttgttgatgg
    21481 tcagatagcc tatactggtg gggtcaatct ggcagatgag tacattaacc acgtcgagag
    21541 atttggttat tggaaggata gtggaattcg cttagacgga ctagcagtaa aagccctgac
    21601 acgcttattt ttgaccactt ggtacattaa tcgaggagaa attagtgatt ttgatcaata
    21661 tcatttagaa aatcattcta tcccgagtga cggtttaacc attccatacg gaagtggacc
    21721 caagccaatt tttcgagcgc aggtagggaa aaaagtttat cagagtttaa tcaatcaagc
    21781 aacagaatcg gtctatatta cgacacctta tttgattata gattatgatt taacagagac
    21841 aatcaaaaat gcagctatga gaggggtcga tgttcgaatt atcacccctt acataccaga
    21901 taagaagttc attcagttag tcacgagagg agcttatccc gaccttcttt ctgctggtgt
    21961 tcggatttat gagtatagtc caggttttat tcatagtaag cagatgttgg tagacgaaga
    22021 ttttgcggtg gtggggacaa tcaatctcga ctaccggagc ttggtacacc attatgaaaa
    22081 tgcagtctta ctctataaaa ctccttctat aagggaaatc gcccgagatt ttcgaaatat
    22141 atttgcagat tctcaggaag tctatcctca ttctatcaaa acgagctggt atcaaaagct
    22201 tgtaaaagaa atcgcccagc tattcgcccc tatcttataa gaaatctaga acttaggata
    22261 caaaccagcc ctatttttct tgtcttttac taatagaaag aaagaggagg ggaattcatg
    22321 ctaactaagg aagaagtgaa tgatatgatt gagttcaaac agacacattt acaccgcttt
    22381 cgggaaattg aaacctttgt gaaactatgc aaaaaatcac tcaaacagcc atcgcaagct
    22441 gacaatccta ggactttttg atatactaag acagataaat tgaacaggag aaacgatatg
    22501 agtgtgtatg gtagagtaga agaagttcat aaggagaatc gtgaacctct agaataccaa
    22561 atcgaacaag aatcgcatca tcgtgaatca agtcgtcttc ctttggtgaa aattttacta
    22621 tggagtacgc ttgtaacggg gataactcta ggagtaccgc tattactcga cttaatgagt
    22681 gcacaagaag tgcaggattt ttatgcaggt tgggcgcttc atcagacagg gaagatttac
    22741 agcgactatt atggaagtca aggtttgctt tattatttgc tgacttacgt gagtcagggc
    22801 ggatttttct ttgccatctt tgagtggtta gccttggtag caggaggatt tttccttttt
    22861 agatcagcgg acaccttgac agagcaagga gaccaagctg gacatctggt gactattttt
    22921 tacatgctag ttacaggtct tgcttttggt ggaggctatg cgactctttt agcgcttcct
    22981 ttcttattcg cagcctttag tttagttgcg gcttacctaa gcaatccaag ccatgataag
    23041 ggatttgtac ggattgggct agctttggca ggcggatttt tctttgctcc cttatcatcg
    23101 ctcctgttta ttgctgtagt gggtttaggc ttgttggtct ttaaccttgg gcatagacgc
    23161 tttgcgcatg ggttttatca gtttcttgca gtggctttag gtttttcact tgtcttttat
    23221 ccaactgcct actatagtgc tgcaacagga agttttgggg atgcgattag tggtattcgt
    23281 tatcctattg acagtattcg ctttgatttt acttctaaaa ttttagagaa tatgtttttt
    23341 tatggcttgt tgtcccttgg tttgggattt gtggtttgta tctttttagg tctctttcaa
    23401 tccaaaccct ttaaactata cgtcatttcg gttcctgcaa gtcttgttgt aattttaggt
    23461 ttgattttac ttttcttttc acaagagcct ctgcacgctt cttatttgat ggtcgtcttc
    23521 cctgttttcc tacttttatt ggtaaccaat attaagagtc aacagagggg gcgtagtgct
    23581 agaagaagcc gaagagaaac gccagttagc ctatggagtc gtttcttcaa aggaaatcta
    23641 tatctgctag tttttgggtt tgtctatctt ttgtctgttc cttttttgat gaagtttgtc
    23701 ctttatccag taccttatca agaacgtaat cgtcttgctg atttggtaaa agaggagaca
    23761 aatacggaag atgctatcta tgcatgggat gatactgcga ctctttatcg taagagtgag
    23821 cgcttgtcgc catcggcgat tttgtccccg ttgcactata cagcaactga ggaaaatcgt
    23881 aataagttac ttaatgactt gaaagaaaaa caacctaagg tgattgtggt aaatgacaag
    23941 gtggtagtct ggtctgaagt ggaaacactt ttaaaagaaa attaccaaca agtaaagact
    24001 gattactcag agtttaaagt ctataaaatt aaataaccaa atcaatatct tgtgtatttt
    24061 tagaaatttt aggattttta acacaagata ttgatttttc tttttagagt ggtataatac
    24121 tttttagaaa gaacatttta gaaaagagca tgcgtatgat tgcactagaa gaaaaaatta
    24181 caattttgcc aactctcttc gtcgagaaac gagatgggag acgtgttgta tttgatgtgg
    24241 acaagattga caaggctctc cacaaggcgg ctgacaaggt tatggatgtg acacccctgg
    24301 ttgaaaaacg cctcaatgat ctgactgagc gaattattac agaaattcat agtcgctttc
    24361 cacagggaat taagatttac gaaattcaaa atatcgtaga acatgaactc cttgaagcca
    24421 aagaatatgc gctggctgag gagtatatta cttatcggac acagagggat tttgagcgct
    24481 caaaagcgac ggatatcaac tttagtattc ataaacttct caacaaagac cagacagttg
    24541 tcaatgaaaa tgctaataaa gacagtgatg tctttaacac tcagcgtgat ttgacagcag
    24601 ggattgttgg gaaatcaatc ggactgcaaa tgcttcctaa gcacgtagcc aatgcccacc
    24661 aaaaggggga tatccactat cacgatttgg actacagtcc ctatacccct atgaccaact
    24721 gctgtttgat tgattttaag ggtatgttgg aaaatggttt taagattgga aatgcagagg
    24781 tagagagtcc caagtctatc cagactgcga cagcacagat ttctcaaatc attgccaacg
    24841 ttgcttctag ccagtacggt ggctgttcag ctgaccgtat cgatgaaatt ttggcgcctt
    24901 atgcagagaa gaactatcaa aaacatctca aagatgcaga agagtgggta ttgcctgaaa
    24961 aacgggaaga ttacgcttgg aagaaaacgc aaaaggacat ctacgatgcc atgcaatctc
    25021 ttgagtatga aatcaatact ctcttcactt caaatggaca aacacctttt acttcgttag
    25081 gttttggtct gggaaccagt cgttttgaac gagaaattca aaaagctatt ttaaacattc
    25141 gcatcaaggg tcttggttca gaacaccgta cggctatctt tcctaaactt attttcactc
    25201 tgaaaagagg ccttaattta gaggaaggaa ctcccaacta cgacatcaag cagttggctc
    25261 ttgagtgtgc aaccaaacgg atgtatccag atgttttatc ttacgataag attgttgact
    25321 tgacaggatc cttcaaggtg cctatgggtt gccgttcttt cctccaagga tggaaggatg
    25381 aaaatggtgt agaagtcaat tcaggtcgca tgaatctggg tgttgtgacg gttaatctgc
    25441 ctcgtattgc tcttgagtct gaaggtgata tgaataagtt ctgggaaatc ttcaacgagc
    25501 gcatgaatat cgcagaagat gctcttgttt accgtgtcga acgcactaaa gaggcgacac
    25561 cagcgaatgc tcctatcctt tatcagtacg gtgcttttgg ccatcatcta ggtaaagaag
    25621 aaagtgttga ccagctcttt aagaatcgtc gtgcgaccgt ttcgctgggc tatatcggct
    25681 tgtatgaagt agcgacagtt ttctttggta acagctggga aagtaatcca gatgctaagg
    25741 aattcacgct agacatcatt cacgatatga aacgccgtgt agaagagtgg tcagaccaat
    25801 atggctacca tttctctatc tactcaacac catccgaaag tctgacagac cgtttctgcc
    25861 gactagatat agacaagttt ggctctattc ctgatatcac agacaaggaa tactacacca
    25921 actctttcca ctacgatgtt cgtaaaaatc caacaccgtt tgaaaaattg gactttgaga
    25981 aagtctatcc agaagcaggt gcgtcaggtg gtttcatcca ttattgtgag tatccagtcc
    26041 ttcagcaaaa tccaaaggcc ttggaagctg tctgggatta tgcttatgac cgtgtaggct
    26101 atctaggcac caatactccg attgaccgtt gctacaagtg tgactttgaa ggggattttg
    26161 aaccaactga gagagggttt gcttgtccaa actgtggcaa tagcgaccct aaaacagtag
    26221 atgtggtgaa gcgaacttgt ggctacctag gtaatcctca agcaagaccg atggtcaacg
    26281 ggcgtcacaa ggaaatcgct gcgcgtgtca aacatatgaa tggttcaacg attaaaatag
    26341 ctgggcatca agtaacaaat tagaaagaaa tgaaatggga aaatatcaac tagacgataa
    26401 ggggcgcgca caagtgaccc gttatcacga gaaacactct aaaggtggag ctggtaagaa
    26461 agaacgcttg cttagcttca gagaacaatt tttaaacaag aacaagaaaa aataaaagtg
    26521 agagccagct ctcgcttttc tcatagtggg aggtaaggat ggaattacgc agaccaagat
    26581 tagcggataa gaaagctgtt ttagatatga tgacagagtt tgaaaaattt cagtcgcctc
    26641 acgacggcgg tttctgggat acagagaact ttgtgtatga agactggtta gaaagcaatc
    26701 aggaacagga aatgggaatt aatctgcctg aaggatgggt tcctgcaatt cagttagtgg
    26761 ctttttctga gaaaggtcaa gcagttggat ttcttaatct ccggttgcgc ctcagtaact
    26821 ttctactaga agaaggtggg cacattggct actccatccg tccatctgaa agaggcaagg
    26881 gttatgcaaa agagactctc cgtcagggct tgcaagttgc taaggaaaag aacatcaaga
    26941 aagctctggt gacctgtagc gtgaataatc ctgctagcag agcagtcatt ctagcaaatg
    27001 gtggaatatt tgaggatgct cgcaatggag tcgagcgtta ttggatagag gtagcgaatg
    27061 aataatccaa aaccacaaga atggaaaagc gaggaactta gtcaaggtcg tatcattgac
    27121 tacaaggcct ttaactttgt tgatggcgaa ggcgtgcgta actctctcta tgtagcaggc
    27181 tgtatgtttc actgcgaggg atgttataat gttgcgactt ggtcttttaa tgctggcatt
    27241 ccctatacag cagaattaga agagcagatc atggcagatc ttggtcagcc ctatgttcaa
    27301 ggtttgactt tgttgggagg ggagcctttt ctcaatactg gcattctctt gccacttgtt
    27361 aagcggattc ggaaagaatt gtcagacaag gacatctggt cctggaccgg ctacacttgg
    27421 gaagaaatga tgttggaaac tccagataaa ctggaactct tgtcactgat tgatattctt
    27481 gtcgatggaa gatatgatcg aactaagaga aatcttatgc tccagtttcg aggttcgtct
    27541 aaccaacgaa ttatcgatgt gcaaaaatcg ctcaaaagtg ggcaagtagt gatttgggac
    27601 aagctcaatg acggaaaaga aagctatgaa caggtgaaga gagaatgaag aaaaaaggct
    27661 tagtagacca actagtctca gagatcgaga cggggaaagt caggacactg ggaatatacg
    27721 gtcatggagc ttcaggtaaa tcaacctttg cacaggaatt gtcccaagct ttagattcta
    27781 ctacagtaaa tttgctagaa acagatccct atatcacctc cggacgctat ttggtagtac
    27841 ccaaggacgc gccgaatcaa aaggtgacag ccagtctgcc agtggcgtat gaactggaga
    27901 gtttgcagag agatatcttt gccttgcagg cgggtatgga tgtcttgaca attgaagaac
    27961 cttggaaggc tagtgaagtc ttgtctggag ccaaaccaat tttgattgtc gaagggatgt
    28021 ctgttggttt tctacccaag gaactctttg aaaaaaccat ctgtttctac acggatgagg
    28081 agaccgaatt aaagcgacgc cttgctagag atacgactgt gagaaatcgc gatgcatcct
    28141 ttatattggc tagccatcag atgagacggg agcagtatct gcgatactat aaagaaactg
    28201 agtctaaggc ggatatctta gtggaccaat cagaagataa atttgatgtc aagaggactt
    28261 aacttatgta tagaagaaaa tccctaattt tagaaagaaa aagtaggaaa acagtttcat
    28321 ctcaaaaaaa cgaaaaaacc taacaaatcc cttgcaatcg caggggattt gtgttattct
    28381 attatggtgc tgtaaattac agccttagtt ttgatgcaag aggttgcgac acgctcggtt
    28441 gcattgccac gcaacgccgc gtcggttttc ttgtggagct agcctattat cttaaataga
    28501 cgaaaaggag aaaaagatgg caaacaaaaa aatccgtatc cgtttgaaag cttacgaaca
    28561 ccgtacgctt gacacagcgg ctgcaaaaat cgtagaatca gctactcgta caggtgcaca
    28621 agttgcgggt ccaatcccac ttccaactga acgtagcctc tacacaatca ttcgtgcgac
    28681 tcacaaatac aaagactctc gcgaacaatt tgaaatgcgt acacacaaac gtttgatcga
    28741 tatcgttaac ccaactcaaa aaacagttga tgccttgatg aaattggatc ttccaagtgg
    28801 tgtaaacgta gaaatcaaac tttaatctaa aatataaaag agcagaggct ggtgtttcaa
    28861 tctaattgaa cacgggctaa actcggtgtg aaaaagataa acttcctcgc gtctgctaga
    28921 cactgcgtta gtttcctatt ttcactttga gtttgacgcc ctttgtatct tagacttgag
    28981 cataaaaaac gctcgttaaa aactttttga ataaaaaata tagaaaagga actattttct
    29041 catgacaaaa ggaatcttag ggaaaaaagt gggaatgact caaatcttca ctgaagctgg
    29101 cgaattgatc cctgtaacag ttattgaagc aactccaaac gttgttcttc aagttaaaac
    29161 tgttgaaaca gacggataca acgctatcca agttggtttc gatgacaaac gcgaagtatt
    29221 gagcaacaaa cctgctaaag gacatgtagc gaaagctaac acggctccta agcgcttcat
    29281 tcgtgaattc aaaaacgttg aaggcttgga agttggtgct gaaattacag ttgaaacatt
    29341 cgcagctgga gacgttgttg acgtaactgg tacttctaaa ggtaaaggtt tccaaggtgt
    29401 tatcaaacgc cacggacaat cacgtggacc aatggctcac ggttctcgtt accaccgtcg
    29461 tccaggttct atgggacctg ttgcacctaa ccgcgtattc aaaggtaaaa accttgcagg
    29521 gcgtatgggt ggcgaccgcg taacaattca aaaccttgaa gttgtacaag ttgttccaga
    29581 aaagaacgtt atccttatca aaggtaacgt accaggtgct aagaaatctc ttatcactat
    29641 caaatcagca gttaaagctg gtaaataata aagaaagggg aaatcagtca caatggcaaa
    29701 cgtaacatta tttgaccaaa ctggtaaaga agctggccaa gttgttctta gcgatgcagt
    29761 atttggtatc gaaccaaatg aatcagttgt gtttgatgta atcatcagcc aacgcgcaag
    29821 ccttcgtcaa ggaacacacg ctgttaaaaa ccgctctgca gtatcaggtg gtggacgcaa
    29881 accatggcgt caaaaaggaa ctggacgtgc tcgtcaaggt tctatccgct caccacaatg
    29941 gcgtggtggt ggtgttgtct tcggaccaac tccacgttca tacggctaca aacttccaca
    30001 aaaagttcgt cgcctagctc ttaaatcagt ttactctgaa aaagttgctg aaaacaaatt
    30061 cgtagctgta gacgctcttt catttacagc tccaaaaact gctgaatttg caaaagttct
    30121 tgcagcattg agcatcgatt ctaaagttct tgttatcctt gaagaaggaa atgaattcgc
    30181 agctctttca gctcgtaacc ttccaaacgt gaaagttgca actgctacaa ctgcaagtgt
    30241 tcttgacatc gcaaatagcg acaaacttct tgtcacacaa gcagctatct ctaaaatcga
    30301 ggaggttctt gcataatgaa tttgtatgat gttatcaaaa aacctgtcat cactgaaagc
    30361 tcaatggctc aacttgaagc aggaaaatat gtatttgaag ttgacactcg tgcacacaaa
    30421 cttttgatca agcaagctgt tgaagctgct ttcgaaggtg ttaaagttgc caatgttaac
    30481 acaatcaacg taaaaccaaa agctaaacgt gttggacgtt acactggttt tactaacaaa
    30541 actaaaaaag ctatcatcac acttacagct gattctaaag caatcgagtt gtttgctgct
    30601 gaagctgaat aatctaagga ggaaatatcg tgggaattcg tgtttataaa ccaacaacaa
    30661 acggtcgccg taatatgact tctttggatt tcgctgaaat cacaacaagc actcctgaaa
    30721 aatcattgct tgttgcattg aagagcaagg ctggtcgtaa caacaacggt cgtatcacag
    30781 ttcgtcacca aggtggtgga cacaaacgtt tctaccgttt ggttgacttc aaacgtaata
    30841 aagacaacgt tgaagcagtt gttaaaacaa tcgagtacga tccaaaccgt tctgcaaaca
    30901 tcgctcttgt acactacact gacggtgtga aagcatacat catcgctcca aaaggtcttg
    30961 aagtaggtca acgtatcgtt tcaggtccag aagcagatat caaagtcgga aacgctcttc
    31021 cacttgctaa catcccagtt ggtactttga ttcacaacat cgagttgaaa ccaggtcgtg
    31081 gtggtgaatt ggtacgtgct gctggtgcat ctgctcaagt attgggttct gaaggtaaat
    31141 acgttcttgt tcgtcttcaa tcaggtgaag ttcgtatgat tcttggaact tgccgtgcta
    31201 cagttggtgt tgtcggaaac gaacaacatg gacttgtaaa ccttggtaaa gcaggacgta
    31261 gccgttggaa aggtatccgc ccaacagttc gtggttctgt aatgaaccct aacgatcacc
    31321 cacacggtgg tggtgaaggt aaagcaccag ttggtcgtaa agcaccatct actccatggg
    31381 gcaaacctgc tcttggtctt aaaactcgta acaagaaagc gaaatctgac aaacttatcg
    31441 ttcgtcgtcg caacgagaaa taatattaaa ctagtcgctt aagcaactag taaatccgcc
    31501 agctcggtag cgctccatag gagtgcaagc cgctgtggta caacatttaa aggagaaaat
    31561 ataaaaatgg gacgcagtct taaaaaagga cctttcgtcg atgagcattt gatgaaaaaa
    31621 gttgaagctc aagctaacga cgaaaagaaa aaagttatta aaacttggtc acgtcgttca
    31681 acgatcttcc caagtttcat tggttacact attgcagttt atgacggacg taaacacgta
    31741 cctgtttaca tccaagaaga catggtaggc cacaaacttg gtgaatttgc accaactcgt
    31801 acttacaaag gtcacgctgc agacgacaag aaaacacgta gaaaataagg agaacataaa
    31861 tggcagaaat tacttcagct aaagcaatgg ctcgtacagt acgtgtttca cctcgtaaat
    31921 cacgtcttgt tcttgataac atccgtggta aaagcgtagc cgatgcaatc gcaatcttga
    31981 cattcactcc aaacaaagct gctgaaatca tcttgaaagt tttgaactca gctgtagcta
    32041 acgctgaaaa caactttggt ttggataaag ctaacttggt agtatctgaa gcattcgcaa
    32101 acgaaggacc aactatgaaa cgtttccgtc cacgtgcgaa aggttcagct tcaccaatca
    32161 acaaacgtac agctcacatc actgtagctg ttgcagaaaa ataaggaggt aaaatcgtgg
    32221 gtcaaaaagt acatccaatt ggtatgcgtg tcggcatcat ccgtgattgg gatgccaaat
    32281 ggtatgctga aaaagaatac gcggattacc ttcatgaaga tcttgcaatc cgtaaattcg
    32341 ttcaaaaaga acttgctgac gcagcagttt caactattga aatcgaacgc gcagtaaaca
    32401 aagttaacgt ttcacttcac actgctaaac caggtatggt tatcggtaaa ggtggtgcta
    32461 acgttgatgc actccgtgca aaacttaaca aattgactgg aaaacaagta cacatcaaca
    32521 tcatcgaaat caaacaacct gatttggatg ctcaccttgt aggtgaagga attgctcgtc
    32581 aattggagca acgtgttgct ttccgtcgtg cacaaaaaca agcaatccaa cgtgcaatgc
    32641 gtgctggagc taaaggaatc aaaactcaag tatcaggtcg tttgaacggt gcagatatcg
    32701 cccgtgctga aggatactct gaaggaactg ttccgcttca cacacttcgt gcagatatcg
    32761 attacgcttg ggaagaagca gatactacat acggtaaact tggtgttaaa gtatggatct
    32821 accgtggtga agttcttcca gctcgtaaaa acactaaagg aggtaaataa ccaatgttag
    32881 tacctaaacg tgttaaacac cgtcgtgagt tccgtggaaa aatgcgcggt gaagcaaaag
    32941 gtggaaaaga agtagcattc ggtgaatacg gtcttcaagc tacaactagc cactggatca
    33001 ctaaccgcca aatcgaagct gctcgtatcg ccatgactcg ttacatgaaa cgtggtggta
    33061 aagtttggat taaaatcttc ccacacaaat catacactgc taaagctatc ggtgtgcgta
    33121 tgggatctgg taaaggggca cctgaaggtt gggtagcacc agttaaacgt ggtaaagtga
    33181 tgttcgaaat cgctggtgta tctgaagaga ttgcacgtga agcgcttcga cttgctagcc
    33241 acaaattgcc agttaaatgt aaattcgtaa aacgtgaagc agaataagga gaaggcatga
    33301 aacttaatga agtaaaagaa tttgttaaag aacttcgtgg tctttctcaa gaagaactcg
    33361 cgaagcgcga aaacgaattg aaaaaagaat tgtttgaact tcgtttccaa gctgctactg
    33421 gtcaattgga acaaacagct cgcttgaaag aagttaaaaa acaaatcgct cgtatcaaaa
    33481 cagttcaatc tgaagcgaaa taatagacta gggaaggaga aatttcaatg gaacgcaata
    33541 atcgtaaagt tcttgttgga cgtgttgtat ctgacaaaat ggacaagaca atcacagttg
    33601 tagttgaaac aaaacgtaac cacccagtct atggtaaacg tattaactac tctaaaaaat
    33661 acaaagctca tgatgaaaac aatgttgcca aagaaggcga tatcgtacgt atcatggaaa
    33721 ctcgcccgct ttcagctaca aaacgtttcc gtcttgtaga agttgttgaa gaagcggtca
    33781 tcatctaatc aaacctgaaa ggagaaaact gaaatgattc aaacagaaac tcgtttgaaa
    33841 gtcgcagaca acagcggtgc tcgcgaaatc ttgactatca aagttcttgg tggttcagga
    33901 cgtaaatttg caaacatcgg tgatgttatc gtggcatctg taaaacaagc tactcctggt
    33961 ggtgcggtta aaaaaggtga cgttgttaaa gcagttatcg ttcgtactaa atcaggtgct
    34021 cgtcgtgctg atggttcata catcaaattt gacgaaaacg cagcagttat catccgtgaa
    34081 gacaaaactc ctcgcggaac acgtatcttt ggcccagttg cacgtgaatt gcgtgaaggt
    34141 ggcttcatga agatcgtgtc acttgctcca gaagtacttt aatttttagg aacaaactag
    34201 tcccctagct tcaagctagg gtgcccttat gggcgtaaga aaaatcaagg agaaacctaa
    34261 tgtttgtaaa aaaaggcgac aaagttcgcg taatcgctgg taaagacaag ggaacagaag
    34321 ctgttgtcct tactgccctt ccaaaagtaa acaaagttat cgttgaaggt gttaacattg
    34381 ttaagaaaca ccaacgtcca actaacgagc ttcctcaagg tggtatcatc gagaaagaag
    34441 cagctatcca cgtatcaaac gttcaagttt tggacaaaaa tggtgtagct ggtcgtgttg
    34501 gatacaaatt tgtagacggt aaaaaagttc gctacaacaa aaaatcaggc gaagtgcttg
    34561 attaatcacg aaggaaagga gaagtataat ggcaaatcgt ttaaaagaaa aatatcttaa
    34621 tgaagtagtt cctgctttga cagaacaatt caactactca tcagtgatgg ctgtgcctaa
    34681 agtagataag attgttttga acatgggtgt tggtgaagct gtatcaaacg ctaaaagcct
    34741 tgaaaaagct gctgaagaat tggcacttat ctcaggtcaa aaaccactta tcactaaagc
    34801 taaaaaatca atcgccggct tccgtcttcg tgaaggtgtt gcgatcggtg caaaagttac
    34861 ccttcgtggt gaacgtatgt acgaattctt ggataaattg gtatcagttt cacttccacg
    34921 tgtacgtgac ttccacggtg tcccaacaaa atcatttgat ggacgcggga actacacact
    34981 tggtgtgaaa gaacaattaa tcttcccaga aatcaacttc gatgacgttg acaaaactcg
    35041 tggtcttgac atcgttatcg taacaactgc taacactgac gaagagtcac gtgcattgct
    35101 tacaggcctt ggaatgcctt ttgcaaaata atataggagg taaatctaat ggctaaaaaa
    35161 tcaatggtag ctagagaggc taaacgccaa aaaattgttg accgttatgc tgaaaaacgt
    35221 gctgcattaa aggcggcagg ggactacgaa ggtttatcta aattacctcg caacgcctca
    35281 ccgactcgtt tacataatcg ttgtagagtt acggggcgcc cacattcagt ttaccgcaaa
    35341 tttggtctga gtcgtatcgc ttttcgcgaa cttgcgcata aaggtcaaat tcctggtgta
    35401 acaaaagcat cttggtaatt taagatatca agggtgtcaa aactccaagt aaaaatagga
    35461 aacttgacga agaaactaaa gtttctagga aagtttatct ttttcacaca gagtttagcc
    35521 cgggttcaat tgggcttgcc aatttgaacc cgagctacag ctttggcaaa aaagaccaat
    35581 ttgctttgga gcattgcttc tgcattaaat tgtctatttt tgctcgtgct gttacgctct
    35641 ttgtatcatg tattaactag caagtgcaac ttgcaaacta ctagtaagag gagaaaaaca
    35701 aaatggttat gactgaccca atcgcagact tcctaactcg tattcgtaat gctaaccaag
    35761 ctaaacacga agtacttgaa gtacctgcat caaacatcaa aaaagggatt gctgaaatcc
    35821 ttaaacgcga aggttttgta aaaaacgttg aaatcattga agatgacaaa caaggcgtca
    35881 tccgtgtatt tcttaaatac ggaccaaatg gtgagaaagt tatcactaac ttgaaacgtg
    35941 tttctaaacc aggacttcgt gtctacaaaa aacgtgaaga ccttccaaaa gttcttaacg
    36001 gacttggaat tgccatcctt tcaacttctg aaggtttgct tactgataaa gaagcacgcc
    36061 aaaagaatgt tggtggtgag gttatcgctt acgtttggta aaatcaagat acaaagctcg
    36121 taaagaacaa agcaaaatta ggaagttgga gaagtttgtt tacaaacaag ccaacttatc
    36181 tattttgcac agttcttaga gcgtgttcag ttcagctctt gaactaaata agtatctgaa
    36241 ccccgtgaaa actggccgtt ctggcctgac aatttaacag gagaaaataa acatgtcacg
    36301 tattggtaat aaagttatcg tgttgcctgc tggtgttgaa ctcgctaaca atgacaacgt
    36361 tgtaactgta aaaggaccta aaggagaact tactcgtgag ttctcaaaag atattgaaat
    36421 ccgtgtggaa ggtactgaag taactcttca ccgtccaaac gattcaaaag aaatgaaaac
    36481 tatccacgga actactcgtg cccttttgaa caacatggtt gttggtgtat cagaaggatt
    36541 caagaaagaa cttgaaatgc gtggggttgg ttaccgtgca cagcttcaag gatctaaact
    36601 tgttttggct gttggtaaat ctcatccaga cgaagttgaa gctccagaag gaattacttt
    36661 tgaacttcca aacccaacaa caatcgttgt tagcggaatt tcaaaagaag tagttggtca
    36721 aacagctgct tacgtacgta gccttcgttc accagaacca tataaaggta aaggtatccg
    36781 ttacgttggt gaattcgttc gccgtaaaga aggtaaaaca ggtaaataat gttgagtggt
    36841 tgatcatcaa ccaccaacct attttccaac tttgtgcata gcacacgatt taaaactaaa
    36901 gaggtgaaaa ctgtgatttc aaaaccagat aaaaacaaac tccgccaaaa acgtcaccgt
    36961 cgcgttcgcg gaaaactctc tggaactgct gatcgcccac gtttgaacgt attccgttct
    37021 aatacaggca tctacgctca agtgattgat gacgtagcgg gtgtaacgct cgcaagtgct
    37081 tcaactcttg ataaagaagt ttcaaaagga actaaaactg aacaagccgt tgctgtcggt
    37141 aaactcgttg cagaacgtgc aaacgctaaa ggtatttcag aagtggtgtt cgaccgcggt
    37201 ggatatctat atcacggacg tgtgaaagct ttggctgatg cagctcgtga aaacggattg
    37261 aaattctaat aggaggacac tagaaaatgg catttaaaga caatgcagtt gaattagaag
    37321 aacgcgtagt tgctgtcaac cgtgttacaa aagttgttaa aggtggacgt cgtcttcgtt
    37381 tcgcagctct tgttgttgtt ggtgaccaca atggtcgcgt aggatttggt actggtaaag
    37441 ctcaagaagt tccagaagca atccgtaaag cagtagatga tgctaagaaa aacttgatcg
    37501 aagttcctat ggttggaaca acaatcccac acgaagttct ttcagaattc ggtggagcta
    37561 aagtattgtt gaaacctgct gtagaaggtt ctggagttgc cgctggtggt gcagttcgtg
    37621 ccgttgtgga attggcaggt gtggcagata ttacatctaa atcacttggt tctaacactc
    37681 caatcaacat tgttcgtgca actgttgaag gtttgaaaca attgaaacgc gctgaagaaa
    37741 ttgctgccct tcgtggtatt tcagtttctg atttggcata agaaagggga taaaatggct
    37801 caaattaaaa ttactttgac taagtctcca atcggacgca ttccatcaca acgtaaaact
    37861 gttgtagcac ttggacttgg caaattgaac agctctgtta ttaaagaaga taacgctgct
    37921 atccgtggta tgatcacagc agtatctcac ttagtaacag ttgaagaagt aaactaatga
    37981 agttttaggg gatgtgcact gtaccatccc ctaaaactag atatagtcat ctatgatgac
    38041 atcgtatagg cgagttgatg ggggagacaa ccttttctcc cttatcggcg ctagcatttt
    38101 acaaaagagg agaaaataaa aatgaaactt catgaattga aacctgcaga aggttctcgt
    38161 aaagtacgta accgcgttgg tcgtggtact tcatcaggta acggtaaaac atctggtcgt
    38221 ggtcaaaaag gtcaaaaagc tcgtagcggt ggcggagttc gccttggttt tgaaggtgga
    38281 caaactccat tgttccgtcg tcttccaaaa cgtggattca ctaacatcaa cgctaaagaa
    38341 tacgcaattg tgaaccttga ccaattgaac gtctttgaag atggtgctga agtaactcca
    38401 gttgttctta tcgaagcagg aattgttaaa gctgaaaagt caggtattaa aattcttggt
    38461 aacggtgagt tgactaagaa attgactgtg aaagcagcta aattctctaa atcagctgaa
    38521 gaagctatca ctgctaaagg tggttcagta gaagtcatct aagagaggtg acctatgttt
    38581 tttaaattat taagagaagc tcttaaagtc aagcaggttc gatcaaaaat tttatttaca
    38641 atttttatcg ttttggtctt tcgtatcgga actagcatta cagttcctgg tgtgaatgcc
    38701 aatagcttga atgctttaag tggattatcc ttcttaaaca tgttgagctt ggtgtcgggg
    38761 aatgccctaa aaaacttttc gatttttgcc ctaggagtta gtccctatat caccgcttct
    38821 attgttgtcc aactcttgca aatggatatt ttacccaagt ttgtagagtg gggtaaacaa
    38881 ggggaagtag gtcgaagaaa attgaatcaa gctactcgtt atattgctct agttctcgct
    38941 tttgtgcaat ctatcgggat tacagctggt tttaatacct tggctggagc tcaattgatt
    39001 aaaactgctt taactccaca agtttttctg acgattggta tcatcttaac agctggtagt
    39061 atgattgtca cttggttggg tgagcaaatt acagataagg gatacggaaa cggtgtttcc
    39121 atgattatct ttgccgggat tgtttcctca attccagaga tgattcaggg catctatgtg
    39181 gactactttg tgaacgtccc aagtagccgt atcacttcat ctatcatttt cgtaatcatt
    39241 ttgattatta ctgtattgtt gattatttac tttacaactt atgttcaaca agcagaatac
    39301 aaaattccaa tccaatatac taaggttgca caaggtgctc catctagctc ttaccttccg
    39361 ttaaaggtaa accctgctgg agttatccct gttatctttg ccagttcgat tactgcagcg
    39421 cctgcggcta ttcttcagtt tttgagtgcc acaggtcatg attgggcttg ggtaagggta
    39481 gcacaagaga tgttggcaac tacttctcca actggtattg ccatgtatgc tttgttgatt
    39541 attctcttta cattcttcta tacgtttgta cagattaatc ctgaaaaagc agcagagagc
    39601 ctacaaaaga gtggtgccta tatccatgga gttcgtcctg gtaaaggtac agaagaatat
    39661 atgtctaaac ttcttcgtcg tcttgcaact gttggttccc tcttccttgg tgtgatttcc
    39721 attttaccga ttgcagctaa agatgtattt ggtctttctg atgttgttgc ctttggtgga
    39781 acaagtctct tgatcattat ctctacaggt atcgaaggaa tcaagcaatt ggaaggttac
    39841 ctattgaaac gtaagtatgt tggtttcatg gacagaacag aataaaagta tttactgaat
    39901 cagtaaatac tgagggagtg gaggtttaaa ctctgacatt tgtaagagtt ggatctcccc
    39961 tcttctattt tgtttttaaa taggggtgaa aagacttttt gcttctattt aaaaataaaa
    40021 taaggagatc aaatcatgaa tcttttgatt atgggcttac ctggtgcagg taagggaact
    40081 caagcagcaa aaatcgtaga acaattccat gttgcacata tctcaacagg tgatatgttc
    40141 cgcgctgcaa tggcaaatca aactgaaatg ggtgttcttg ctaagtcata tattgacaag
    40201 ggtgaattgg ttcctgacga agttacaaat ggaatcgtaa aagaacgcct ttcacaagat
    40261 gatattaaag aaacaggatt cttattggat ggttacccac gtacaattga acaagctcat
    40321 gccttggaca aaacattggc tgaacttggc attgaactag aaggtattat caatattgaa
    40381 gtgaaccctg acagcctctt ggaacgtttg agtggccgta tcatccaccg cgtaactgga
    40441 gaaactttcc acaaggtctt taacccacca gttgactata aagaagaaga ttactaccaa
    40501 cgtgaagatg ataagcctga gacagtaaaa cgtcgtttgg atgttaatat tgctcaagga
    40561 gaaccaatca ttgctcacta ccgtgccaaa ggtttggttc atgacatcga aggtaatcaa
    40621 gatatcaatg atgtcttctc agatattgaa aaagtattga caaatttgaa ataaagcgtt
    40681 tttcgcactt gcaaaaatcc gctacaaatg ttatactgag atagtctgac ttataattgt
    40741 tgtctctgtg tctagaggca tcgaatcgaa atttatggag gtgcttttgc gtggcaaaag
    40801 acgatgtgat tgaagttgaa ggcaaagtag ttgatacaat gccgaatgca atgtttacgg
    40861 ttgaacttga aaatggacat cagattttag caacagtttc tggtaaaatt cgtaaaaact
    40921 atattcgtat tttagcggga gatcgtgtta ctgtcgaaat gagtccatat gacttgacac
    40981 gtggacgtat cacttaccgc tttaaataat cgaaaaactt ggagggataa gaaatgaaag
    41041 taagaccatc ggtcaaacca atttgcgaat actgtaaagt tattcgtcgt aatggtcgtg
    41101 ttatggtaat ttgcccagca aatccaaaac acaaacaacg tcaaggataa gatagaaagg
    41161 agaaaacatg gctcgtattg ctggagttga tattccaaat gacaaacgcg tagtaatctc
    41221 attgacttat gtttatggta tcggacttgc aacatctaag aaaattttgg ctgctgctgg
    41281 aatctcagaa gatgttcgtg tacgtgatct tacatcagat caagaagatg ctatccgtcg
    41341 tgaagtggat gcaatcaaag ttgaaggtga ccttcgtcgt gaagtaaact tgaacatcaa
    41401 acgtttgatg gaaatcggtt cataccgtgg tatccgtcac cgtcgtggac ttcctgtccg
    41461 tggacaaaac actaaaaaca acgctcgcac tcgtaaaggt aaagctgttg cgattgctgg
    41521 taagaaaaaa taatatagga ggtaaaagtc ttggctaaac caacacgtaa acgtcgtgtg
    41581 aaaaagaata tcgaatctgg tattgctcat attcacgcta catttaataa cactattgtt
    41641 atgattactg atgtgcatgg taatgcaatt gcttggtcat cagctggtgc tcttggtttc
    41701 aaaggttctc gtaaatctac accattcgct gctcaaatgg cttctgaagc tgctgctaaa
    41761 tctgcacaag aacacggtct taaatcagtt gaagttactg taaaaggtcc aggttctggt
    41821 cgtgagtcag ctattcgtgc gcttgctgcc gctggtcttg aagtaacagc aattcgtgat
    41881 gtgactccag tgccacacaa tggtgctcgt cctccaaaac gtcgccgtgt ataatcatcg
    41941 cattacactg cttttcgttt aagagggagt aactaaatga tcgagtttga aaaaccaaat
    42001 ataacaaaaa ttgatgaaaa taaagattat ggcaagtttg taatcgaacc acttgaacgt
    42061 ggctacggta caactcttgg taactctctt cgtcgtgtac ttctagcttc tctaccagga
    42121 gcagctgtga catctatcaa cattgatggt gtgttacatg agtttgacac agttccaggt
    42181 gttcgtgaag acgtgatgca aatcattctg aacattaaag gaattgcagt gaaatcgtac
    42241 gttgaagacg aaaaaatcat cgaactggat gttgaaggtc ctgctgaagt aacagctggt
    42301 gacattttga cagatagcga tattgaaatt gtaaatccag atcattatct ctttacaatc
    42361 ggtgaaggtt cttctctaaa agcgactatg actgttaaca gtggtcgtgg atatgtacct
    42421 gctgatgaaa ataaaaagga taatgcacca gttggaacac ttgctgtaga ttctatttat
    42481 acaccagtta caaaagtcaa ctatcaagtg gaacctgctc gtgtaggtag caatgatggt
    42541 ttcgacaaat taacccttga aatcttgaca aatggaacaa ttattccaga agatgcttta
    42601 gggctttcag cacgtatttt gacagaacat cttgatttgt ttacaaatct tactgagatt
    42661 gctaagtcaa ctgaagtgat gaaagaagct gatactgaat ctgacgaccg tattttagat
    42721 cgtacgattg aggaactgga cttgtctgtg cgttcataca actgtttaaa acgtgccggt
    42781 atcaatactg tgcatgattt gacagaaaaa tctgaagcag agatgatgaa agtacgaaat
    42841 cttggacgca agagtttgga agaagtgaaa ctcaaactca ttgatttggg tcttggatta
    42901 aaagataaat aaaggaggaa tacatggctt accgtaaact aggacgcact agctcacaac
    42961 gtaaagcaat gcttcgcgat ttgacaactg accttttgat caacgaatca atcgtgacaa
    43021 ctgaagctcg tgctaaagaa atccgtaaaa ctgttgaaaa aatgattact ctaggtaaac
    43081 gtggtgattt gcatgcacgt cgtcaagcag ctgctttcgt acgtaatgaa atcgcatctg
    43141 aaaactatga tgaagcaact gataagtaca cttctactac agcacttcaa aaattgttct
    43201 cagaaatcgc acctcgttat gctgaacgta acggtggata cactcgtatc cttaaaactg
    43261 aaccacgtcg tggtgatgca gcgccaatgg cgatcatcga attagtataa aatcatcaat
    43321 tttgttgagt gttatgatga tggagtcttg tgctcttagt ctagctctgg tctaccgcta
    43381 ggatttcggt cctagcggga acactcatca taagttggga tagtagacgc ttgtttacga
    43441 aattgttttt ttcttaagaa caacttcgta agcaggcgtt tttgagtatt ttcgttagaa
    43501 ttatgctata ctatttgaaa agaatcctgt ttaatgttaa ggtttcttat tttaagaaga
    43561 attggagttt acttatgaaa gccattataa ctgttgttgg taaagataaa tctggaattg
    43621 ttgcaggtgt ttctggtaaa attgcagaat taggattgaa tattgacgat atctctcaaa
    43681 ctgtcttgga tgaatatttt acgatgatgg ctgttgtatc tagtgatgaa aagcaagatt
    43741 ttacctatct tcgtaatgaa tttgaagctt ttgggcaaac tttgaatgta aaaatcaata
    43801 ttcagagtgc agcgattttc gaagctatgt ataatatcta ggaggtcatc atggatatta
    43861 gacaagttac tgaaaccatc gccatgattg aggagcaaaa cttcgatatt agaaccatta
    43921 ccatggggat ttctcttttg gactgtatcg atccagatat caatcgtgct gcggagaaaa
    43981 tctatcaaaa aattacgaca aaggcggcta atttagtagc tgttggtgat gaaattgcgg
    44041 ctgagttggg aattcctatc gttaataagc gtgtatcggt gacacctatt tctctgattg
    44101 gggcagcgac agatgcgacg gactacgtgg ttctggcaaa agcgcttgat aaggctgcga
    44161 aagagattgg tgtggacttt attggtggtt tttctgcctt agtacaaaaa ggttatcaaa
    44221 agggagatga gattctcatc aattccattc ctcgcgcttt ggctgagacg gataaggtct
    44281 gctcgtcagt caatatcggc tcaaccaagt ctggtattaa tatgacggct gtggcagata
    44341 tgggacgaat tatcaaggaa acagcaaatc tttcagatat gggagtggcc aagttggttg
    44401 tattcgctaa tgctgttgag gacaatccat ttatggcggg tgcctttcat ggtgttgggg
    44461 aagcagatgt tatcatcaat gtcggagttt ctggtcctgg tgtggtgaaa cgtgctttgg
    44521 aaaaagttcg tggacagagc tttgatgtag tagccgaaac agttaagaaa actgccttta
    44581 aaatcactcg tatcggtcaa ttggttggtc aaatggccag tgagagactg ggtgtggagt
    44641 ttggtattgt ggacttgagt ttggcaccaa cccctgcggt tggagactct gtggcacgtg
    44701 tccttgagga aatggggcta gaaacagttg gcacgcatgg aacgacagct gccttggccc
    44761 tcttgaacga ccaagttaaa aagggtggag tgatggcctg taaccaggtc ggtggtctat
    44821 ctggtgcctt tatccctgtt tctgaggatg aaggaatgat tgctgcagtg caaaatggct
    44881 ctcttaattt agaaaaacta gaagctatga cggctatctg ttctgttgga ttggatatga
    44941 ttgccatccc agaagatacg cctgctgaaa ccattgcggc tatgattgcg gatgaagcag
    45001 caatcggtgt tatcaacatg aaaacaacag ctgttcgtat cattcccaaa ggaagagaag
    45061 gcgatatgat tgagtttggt ggtctattag gaactgcacc cgttatgaag gttaatgggg
    45121 cttcgtctgt cgacttcatc tctcgcggtg gacaaatccc agcaccaatt catagtttta
    45181 aaaattaaga aaataggaga aattttaagt tctatttaag attagatgtg tatactataa
    45241 tcattaaata aagacctcct aatattattt gaaacagata acactgaatt agtttgaatt
    45301 tgattttcat ctaatatctt tatttaatga actcctaaac tttttcataa taatctcctt
    45361 caaaagtcgc ctgtatgggt ggcttttatt ttatcattca tgatataata gaagcaaacg
    45421 gaggacggaa aatggtaaaa gtacgattgt atttggtacg tcatggcaag accatgttta
    45481 acacgattgg tcgcgcgcaa ggttggagcg atactccctt aactgctgaa ggtgaacgag
    45541 ggattcaaga gttaggaatc ggtttgcgag aatctgatct acagtttgag cgcgcttatt
    45601 cgagtgattc tggtcgtacc attcagacca tgggaattat acttgaagaa cttggcttgc
    45661 aggggaaaat cccttatcgc atggacaagc gtatcagaga atggtgtttc ggtagttttg
    45721 atggagccta tgatggcgat cttttcatgg gcattattcc tcgtatcttt aatgtggacc
    45781 acgttcacca attgtcttat gctgaactgg ctgagggctt ggtagaggtc gatacagctg
    45841 gttgggctga aggttgggaa aaactcagtg gccgaatcaa ggaaggcttt gaaataattg
    45901 caaaagaaat ggaagatcaa ggtggaggta acgcccttgt tgtcagccat ggaatgacta
    45961 ttggaaccat tgtttatctg attaatggca tgcatccgca tggtctagat aatggtagcg
    46021 tgacgattct tgaatatgag gacggtcagt ttagggttga agttgtcggt gaccgtagtt
    46081 accgagagct aggacgtgag aagatggaag aaggttctat ttaatcagtc tagacttgct
    46141 tgccatgagc tagggatttg ataagaatat caagataaga aaaaacagcc gagggtactc
    46201 ctttcggctg tttttgatgt ggaaaactaa agtgtaatgc tattgctttt agagattttc
    46261 ataaacaaga gcaaggaacc tactgttaga acagtcagga tagttgacaa ggctgcggct
    46321 acaccgtaat ttcctctgag aatctctgta taaatagcca cagtcattgt tcttgttttg
    46381 acattgtaga ggaggataga agtagagagt tttgaaatca ttgtgaccca agataagatg
    46441 gctccagaaa tgataccaga tagcatcatt ggagttgtaa tcttagcaaa gatattgaga
    46501 cgactacttc ctaagctttc agcagcttct tcaatacttg gtgctatttg ttgtaagcta
    46561 gcaacagatg agcgaatagt ataaggtaat cttctgacag atagagacat aatcaagatg
    46621 aaagcagtcc ctgtaatcat aagaaatcca cttccaaata gaccagtatt gaaggaagaa
    46681 atgaaggcaa tccctagaac ggttcctggt acaatataag gtaccatact gaggctgtca
    46741 attaagtttg taaacaaatt ccgttttcta acggctaggt aggagataaa tgtcgcaaat
    46801 agaacaacta gaactaaggc aatcaaaggg atacgaatgg tattgaaaat agcagatccc
    46861 atacgattga aagctacctt gtaactgttt ggagaataac ctttaacaaa taccatacct
    46921 gatgttttta ggaaagaggt ataaattaag tagatttgag gtaaaacaga gataaagata
    46981 attccgtaga ctgttgcata aatggcagcc atttttcctt ttgtagtttt tttaggctca
    47041 attggatgga gcagattcat gctgaaactg tagcggtttg caatgtgttt ttggataagg
    47101 aaaattgcca aggcaatgat aatcgccata attgcaaaag cagaatttcc tccaacctcg
    47161 ctaataaatt gggtataaat caggacaggg aaagtccgat atccttcgcc aatcaacata
    47221 ggcgttccaa agtctgagaa tgctctcata aatacaagca aggagctgct agtaaggttg
    47281 aaactaggag aggtaaaaca accgttacga taggtttaaa tccgaaggac cccatgcttt
    47341 cagctgcttc aagtagagaa ttgtcaatac tgttcattgt tccagcaaca tatagaaata
    47401 ccagtgggaa tagttgcagt gtaaagacaa gtatacttcc tttgaatcca taaatatcga
    47461 tagctggaag atgaagggca tttgtcaaaa atttagtgat gacctcattt cgtctcagca
    47521 agagaatcca ggagtaggct cctacgaaag gagctgacat ggaagcaatg ataatcaata
    47581 tttgtagaaa tttcttcccc ttgaagtcat acatagagaa gagataagct aatagggttc
    47641 ctacaactaa ggaagtgaca gtagcggtaa tggaaaccct gaaactgttg actagtgtct
    47701 cagagtagta ggttttacta aagaaagtga caaaattagc tagtgagaat tgtccttcat
    47761 gtataagtgc ttgcttgagc acggtaacga taggataaac gagaaagaca agataggtaa
    47821 gaaagatgaa gaaagaggaa gctgtccaaa tatttagttt tttacattcc atggttgact
    47881 ccttttatca ggttttggga accatctgca gaaaagatgt ttaatttttg cgtattgatt
    47941 cgtagacgaa tacgattgcc tttttgtagt tcttcttcaa aagttgattc ttcactaact
    48001 tgaatttttg aggcaaaacc tgtctcaatg aaatactccg tatttagtcc aagatagacg
    48061 ctatcgctaa tagttccttc aatatctcca gattcatctt tgataaactc ttcgggacga
    48121 atgcttacat gaatagcttg ctcctcaacc tgatcaagag ctggcattcg aagggcatag
    48181 ccatctgaaa agacgatata agcgccgtcg ctccgttttt caagattggc agggataata
    48241 tttgtgcgtc cgataaaggt tgccacaaac tcattagctg gtttatgata gagttctttt
    48301 ggtcggccga tttgttggat caccccatct ttcataacag caatttggtc tgaaatagcc
    48361 atggcttctt cttggtcgtg ggttacataa acagttgtaa ttcccacttc gtgttggatt
    48421 tctcggatgg cttgacgcat atccaagcga agtttggcct ccagattact aagtggctcg
    48481 tccatgagga gaacacttgg attaaccgct aaggcgcatg ccaaggtgac acgttgttgt
    48541 tgtccaccac tgagtttatc gggttttcga tccgcatatt gagcaatttg catgagttca
    48601 agatacttgt tggtctgttg aatcaattct tcttttgcat aagaccaaaa gcaacgttgt
    48661 ctcggacagt caaatgtggg aaaatagcgt agttttggaa aaccatcccg atattgcgtt
    48721 tgctgggttc catattattg atttttgtat catcgaagta aaattctcaa tctttgatac
    48781 tgttgaaacc tgcaatcata cgaagaaggg tcgttttccc acatcctgaa gctccaagaa
    48841 gggtaaagag acttcctttt ggaattgtaa tgttcaaatt ctcaataaca gggacatcgt
    48901 ggtagatttt tttggcgtta ataattttga tctcactcat agtgaacctc ttttactgtt
    48961 tagattggat atctgtaaag acttcgttgt atttcttaac gatatctgat ttattcttga
    49021 tgacataatc ataatcttca gtgagtgttt tgattttgtc aattggtttc atgttttcgc
    49081 ttgttttagc atttttacga acaggacggt tagtagtggt tgtaccaagt gtatcttgta
    49141 cttcttgaga gataataaaa tcgataaatt tcttggcatt ttccatattt ttagattttt
    49201 taacgatagc agcactagca ggtaggaaga cggttccttc ttttggatag actaccttaa
    49261 tgttagctcc gtcatttaag agtttaactg ctggatcttc ataagagaga ccaacagtca
    49321 tttctccatc agcgactgct ttatagacac cagatgaact taaaccgatt ttatagta
//
LOCUS       DAVBOG010000009        45265 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.009, whole genome shotgun sequence.
ACCESSION   DAVBOG010000009 DAVBOG010000000
VERSION     DAVBOG010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 45265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45265
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.009"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ865_000546"
     CDS             complement(59..1762)
                     /gene="ilvD"
                     /locus_tag="VQ865_000546"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HET3134955.1"
                     /translation="MTELDKRHRSSIYDSMVKSPNRAMLRATGMTDKDFETPIVGVIS
                     TWAENTPCNIHLHDFGKLAKEGVKSAGAWPVQFGTITVADGIAMGTPGMRFSLTSRDI
                     IADSIEAAMSGHNVDAFVAIGGCDKNMPGSMIAIANMDIPAIFAYGGTIAPGNLDGKD
                     IDLVSVFEGIGKWNHGDMTAEDVKRLECNACPGPGGCGGMYTANTMATAIEVLGMSLP
                     GSSSHPAESADKKEDIEAAGRAVVKMLELGLKPSDILTREAFEDAITVTMALGGSTNA
                     TLHLLAIAHAANVDLSLEDFNTIQERVPHLADLKPSGQYVFQDLYEVGGVPAVMKYLL
                     ANGFLHGDRITCTGKTVAENLADFADLTPGQKVIMPLENPKRADGPLIILNGNLAPDG
                     AVAKVSGVKVRRHVGPAKVFDSEEDAIQAVLTDEIVDGDVVVVRFVGPKGGPGMPEML
                     SLSSMIVGKGQGDKVALLTDGRFSGGTYGLVVGHIAPEAQDGGPIAYLRTGDIVTVDQ
                     DTKEISMAVSEEELEKRKAETTLPPLYSRGVLGKYAHIVSSASRGAVTDFWNMDKSGK
                     K"
     gene            complement(1995..2927)
                     /locus_tag="VQ865_000547"
     CDS             complement(1995..2927)
                     /locus_tag="VQ865_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase family protein"
                     /protein_id="HET3134956.1"
                     /translation="MMRSTKELRHVYRDFLLEANQSDSDIVVLEADLSSSMATHNLEK
                     DFGDRYVNVGIMEAEMVGLAAGLSIQGFRPYLHTFGPFASRRVFDQLFISLGYAQLDA
                     TVIGSDAGVTAEMNGGTHMPFEEIGLLRLIPKSIIFEATDDIQFREILNQTLDLKGLK
                     YIRTIRKAPVPVYQGGEDFSKGYIELRHGEDVVIVASGIMVAPSIRVADELSKLGYSV
                     GVIDLFRIKPIPEQIKTMLSGKTIFTVENHNQIGGIGSAVCELFSDDGITKIHRMGVQ
                     ERFGQVGKMDYLLNEYGLSESNIKEKVLEIYNAR"
     gene            complement(2924..3781)
                     /locus_tag="VQ865_000548"
     CDS             complement(2924..3781)
                     /locus_tag="VQ865_000548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3134957.1"
                     /translation="MILSKNREDGLRKFATNIRLNTLRTLNHLGFGHYGGSLSIVEVL
                     AVLYGEIMPMTPEIFAARDRDYFILSKGHGGPALYSTLYLNGFFDKEFLYSLNTNGTK
                     LPSHPDRNLTPGIDMTTGSLGQGISVATGLAYGQRIRKSPFYTYAIVGDGELNEGQCW
                     EAIQFASHQQLSNLIVFVDDNKKQLDGFTKDICNSGDFVEKFSAFGFESIRVKGSDIR
                     EIYEGIVQLKQSNNSSPKCIVLDTIKGQGVQELEEMKSNHHLRPTVEEKQMLTSVVER
                     LSQELEETE"
     gene            complement(3785..5131)
                     /locus_tag="VQ865_000549"
     CDS             complement(3785..5131)
                     /locus_tag="VQ865_000549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000975284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3134958.1"
                     /translation="MMKFILDIVSTPAILVALIAILGLVLQKKKLPDIIKGGIKTFVG
                     FLVVSGGAGIVQNSLNPFGTMFEHAFHLSGVVPNNEAIVAVALTTYGSATAMIMFAGM
                     VFNILIARFTRFKYIFLTGHHTLYMACMIAVILSVAGFTSLPLILLGGLALGIIMSIS
                     PAFVQKYMVQLTGNDKVALGHFSSLGYWLSGFTGSLIGDKSKSTEDIKFPKSLAFLRD
                     STVSITLSMAVIYIIVAIFAGSEYIEKEISSGTSGLVYALQLAGQFAAGVFVILAGVR
                     LILGEIVPAFKGISERLVPNSKPALDCPIVYTYAPNAVLIGFISSFVGGLVSMAIMIA
                     SGTVVILPGVVPHFFCGATAGVIGNASGGVRGATIGAFLQGILISFLPVFLMPVLGGL
                     GFQGSTFSDADFGLSGIILGMLNQFGSQAGIVIGLVLILAVMFGVSFIKKPSAKEE"
     gene            complement(5144..5428)
                     /locus_tag="VQ865_000550"
     CDS             complement(5144..5428)
                     /locus_tag="VQ865_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008089859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3134959.1"
                     /translation="MLKIGTACGSGLGSSFMVQMNIESVLSDLNVSDVEVEHYDLGGA
                     DPNAADIWIVGRDLADSASHLGDVRILNSIIDMDELRELITKLCEEKGLI"
     gene            complement(5432..7462)
                     /locus_tag="VQ865_000551"
     CDS             complement(5432..7462)
                     /locus_tag="VQ865_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HET3134960.1"
                     /translation="MFDYRALVILMTLMDHCELSLYELSVKVSLPIKEVKEGIDYLVP
                     YLANKGIVLDKKQGRYSLSNRTKQSLTDIIKSDELVLPKSTRLALIYLYTFCRLDFIS
                     NNHYQDFLKVSKNTTLSDIQSLRKIMLDNDLELGYSRAKGYTLHGSEWNKHRLAFQMV
                     SELLESSIGIWGLDYVLSSWGYSLTYDLINQVVKDYYEKLQLVPIVNQLKVCLFGLVF
                     ILCRYQRDVERVCLSETLVSPVIQDITTILLDTVVDLGIIDTVFSEDDYRYITVLLSS
                     CFEGEVDVAPVYFNQLTEAIISRMEDISLLHFKQREGLRENLRRHLIPAYYRLKFGLP
                     SSNEYVLHVKEHYPDLFELVKDSLMPLMDAIDNPIPDSETAYFVIHFGGYLKKADTLP
                     QKCYKAAIICPNGVSSSLMLKENLLALFPQIEFIGTSKIDDLQVKASSDYDMVFSTIK
                     VETEKPNYLVSVMMTEEQAIQLVELVLKDFPNLEYGDFEIEQILNIVKRYGIITQELE
                     LRLALKNYLYQKNDRKEIVPVLEQLITKETYQVSSQKLGWKEAIRLAAKPLLDQDKIT
                     ENYPEAMIQKVEEFGPFINLGKGVAIPHARPDEGVNEIGMSMLVLEEPIYLLDNPEQE
                     VRLLICIAAIDNESHLKALSHLTTILRDKNHVQTLISSKNYDDIKMIIKQED"
     gene            7653..8660
                     /locus_tag="VQ865_000552"
     CDS             7653..8660
                     /locus_tag="VQ865_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3134961.1"
                     /translation="MTEKLINSKPNGVFALILIELTIVLGIFIFIMGVGSENIFGIII
                     GPLLIVIAGLAHAGLKVVKPQEALVLTLFGNYTGTIKEPGFYFVNPFSVAVNPANHTR
                     LGQSGDVSTKSPFLGAKSSNDNDVNLEIGKKHISLKVMTLSNSRQKINDCLGNPVEIG
                     IAVTWRVVDTAKAVFNVDNYKEYLSLQCDSALRNIVRIYPYDVSPNVDTTGDGQADEG
                     SLRGSSEIVANRIREEIQSRVEDAGLEILEARITYLAYAPEIAAVMLQRQQASAIIDA
                     RKMIVDGAVGMVEMALERLNEGELVELDEERKAAMVSNLLVVLCGNHDAQPIVNTGSL
                     Y"
     gene            8663..8863
                     /locus_tag="VQ865_000553"
     CDS             8663..8863
                     /locus_tag="VQ865_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3134962.1"
                     /translation="MAEAKKKQIPLRLSTKLYAALASWAEDDFRSVNGQIEYLLTECV
                     KQRKKDGKYVSETIDEPFEIDI"
     gene            9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ865_000554"
     CDS             9015..9197
                     /gene="rpmF"
                     /locus_tag="VQ865_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HET3134963.1"
                     /translation="MAVPARRTSKAKKNKRRTHYKVTAPSVNFDETTGDYSRSHRVSL
                     KGYYKGRKIAKAASAE"
     gene            9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ865_000555"
     CDS             9213..9362
                     /gene="rpmG"
                     /locus_tag="VQ865_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001265622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3134964.1"
                     /translation="MRVNITLEHKESGERLYLTSKNKRNTPDRLQLKKYSPKLRKHVV
                     FTEVK"
     gene            complement(9784..11664)
                     /locus_tag="VQ865_000556"
     CDS             complement(9784..11664)
                     /locus_tag="VQ865_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3134965.1"
                     /translation="MVRFTGLSPKQTQAIEVLKGHISLPDVEVAVTQSDQASISIEGE
                     EGHYQLTYRKPHQLYRALSLLVTVLAEADKVEIEEQAAYEDLAYMVDCSRNAVLNVAS
                     AKQMIEVLALMGYSTFELYMEDTYQIEGQPYFGYFRGAYSAEELQEIEAYAQQFDMTF
                     VPCIQTLAHLSAFVKWGVKEVQELRDVEDILLIGEEKVYDLIDGMFATLSKLKTRKVN
                     IGMDEAHLVGLGRYLILNGVVDRSLLMCQHLERVLDIADKYGFHCQMWSDMFFKLMSA
                     DGQYDRDVEIPEETRVYLDRLKDRVTLVYWDYYQDSEEKYNRNFRNHHKISHDLAFAG
                     GAWKWIGFTPHNHFSRLVAIEANKACRANQIKEVIVTGWGDNGGETAQFSILPSLQIW
                     AELSYRNDLDSLSAHFKTNTGLTVEDFMQIDLANLLPDLPGNLSGINPNRYVFYQDVL
                     CPILDRHMTPEQDKPHFAQAAETLANIKEKAGNYAYLFETQAQLNAILSSKVDVGRRI
                     RQAYQADDKESLQQIARQELPELRSQIEDFHALFSHQWLKENKVFGLDTVDIRMGGLL
                     QRIKRAESRIEVYLAGQLDRIDELEVEILPFTDFYADKDFAATTANQWHTIATASMIY
                     TT"
     gene            complement(11658..12527)
                     /locus_tag="VQ865_000557"
     CDS             complement(11658..12527)
                     /locus_tag="VQ865_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3134966.1"
                     /translation="MTIATIDIGGTGIKFASLTPDGKILYKTSISTPENLEDLLAWLD
                     QRLSEQDYSGIAMSVPGAVNQETGVIDGFSAVPYIHGFSWYEALSSYQLPVHLENDAN
                     CVGLSELLAHPELENAACVVIGTGIGGAMIINGRLHRGRHGLGGEFGYMTTLAPAEKL
                     NNWSQLASTGNMVRYVIEKSGHTDWDGRKIYQEAAAGNALCQEAIERMNRNLAQGLLN
                     IQYLIDPDVISLGGSISQNPDFIQDVKKAVDNFVDTYEEYTVAPVIQACTYHADANLY
                     GALVNWLQEEKQW"
     gene            complement(12611..15256)
                     /locus_tag="VQ865_000558"
     CDS             complement(12611..15256)
                     /locus_tag="VQ865_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000432759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HET3134967.1"
                     /translation="MENVVVHIISHSHWDREWYLPFESHRMQLVELFDNLFDLFENDP
                     EFKSFHLDGQTIVLDDYLQIRPENRDKVQRYIDEGKLKIGPFYILQDDYLISSEANVR
                     NTLIGQQEAAKWGKSTQIGYFPDTFGNMGQAPQILQKSGIHVAAFGRGVKPIGFDNQV
                     LEDEQFTSQFSEMYWQGVDGSRVLGILFANWYSNGNEIPVDKDEALTFWKQKLSDVRA
                     YASTNQWLMMNGCDHQPVQKNLSEAIRVANELFPDVIFVHSSFDEYVQAVEGALPEHL
                     STVTGELTSQETDGWYTLANTSSSRIYLKQAFQENSNLLEQVVEPLTIITGGHNHKDQ
                     LTYAWKTLLQNAPHDSICGCSVDEVHREMETRFAKVNQVGNFVKSNLLNEWKGKIATD
                     KAQSDYLFTVINTGLHDKVDTVSTVIDVATCDFKELHPTEGYKKMAALILPSYRVEDL
                     DGHPVEATIEDLGANFEYDLPKDKFRQARIARQVRVTIPVHLAPLSWTTFQLLEGKQE
                     HREGIYQNGVIDTPFVTVSVDDNITVYDKTTHEAYEDFIRFEDRGDIGNEYIYFQPKG
                     TEPIFAELKGHEVLENTDRYAKILLKHELTVPVSADEKLEEEQQGIIEFMKREAGRSE
                     ELTNIPLETELTVFVDNPQIRFKTRFTNTAKDHRIRLLVKTHNTRPSNDSESIYEVVT
                     RPNKPAASWENPENPQHQQAFVSLYDDEKGVTVSNKGLNEYEILGDNTIAVTILRASG
                     ELGDWGYFPTPEAQCLREFEVEFALECHQAQERFSAFRRAKALQTPFTSLQLARQEGS
                     VVATGSLLSHSVLSIPQVCPTAFKVAENEEGYVFRYYNMSQENVRISEHQQTILDLLE
                     RPYPVHSGPLDPQEIRTEFIKKEEI"
     gene            complement(15347..16627)
                     /locus_tag="VQ865_000559"
     CDS             complement(15347..16627)
                     /locus_tag="VQ865_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HET3134968.1"
                     /translation="MIYSKEIVREWIDEVAERAKDHPEWVDVFERCYTDTLDNTVEIL
                     EDGSTFVLTGDIPAMWLRDSTAQLRPYLHVAKRDALLRQTIAGLVKRQMTLVLKDPYA
                     NSFNIEENWKGHHETDHTDLNGWIWERKYEVDSLCYPLQLAYLLWKETGETSQFDEIF
                     VAATKEILHLWTVEQDHKNSPYRFVRDTDRKEDTLVNDGFGPDFAVTGMTWSAFRPSD
                     DCCQYSYLIPSNMFAVVVLGYVQEIFAALNLADSQSVIADAKRLQDEIQEGIKNYAYT
                     TNSKGEKIYAFEVDGLGNASIMDDPNVPSLLAAPYLGYCSVDDEVYQATRRTILSSEN
                     PYFYQGEYASGLGSSHTFYRYIWPIALSIQGLTTRDKAEKKFLLDQLVACDGGTGVMH
                     ESFHVDDPTLYSREWFSWANMMFCELVLDYLDIR"
     gene            16798..18882
                     /locus_tag="VQ865_000560"
     CDS             16798..18882
                     /locus_tag="VQ865_000560"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HET3134969.1"
                     /translation="MKPLLETIDTRFGTASKHAFSRGNTLPYTGVPFGMNYFVPQTSD
                     QGGSWFFDPHLPIFQGIRLTHQPSPWIGDYSWLLLTPVTSQLGGDSLFHRQSSYDIDK
                     ACFQPHYLKLFSLRYQIETQLTPTCYGASIRLNQKQGKALSLYLHAADELTVEQVDKR
                     TLALRQEGKTETNKNSLTMFTALQMNTDILAISQEAGDWRIDLASSQTEMQLATSFIS
                     PSQALINLPQEDFDSCKTSAQADWENLLHRFDIIETGEADRTFFDHCLYRLFLFPQTF
                     YEVDESGKAIHMDLATGTVKPGVLFSNNGFWDTFRTTFPLFALIIPEHYQRFLEGFLN
                     SYRDTGFLPKWLAPDERGMMPGTLLDGIIADSACKDMAPDLEGELFQAMLETASKADH
                     LGINGRHGLAQYQELGYLSTDHHESVSHTLDYAYSDFCIASCAKKLENIEIAETYKAA
                     SQNYRQLFDAETGYMRARDNQGNFHPDFSPYSWGRDYAECSAIQATLGVLHDIPGLIQ
                     LMGGKETFSNYLLKACQDAPLFETTGYGYEIHEMSEMATAPFGQIAISNQPSFHIPYL
                     FRYSDYPDYTALLIKTLRQKAFHPSWEAYPGDEDNGSLSAWYIWSALGFYPTCPGKPS
                     YDLGIPLFDHLRVYLAKEDKWLDIHTKQNHNHFNFVKECRLNKTLVSTIQHQDLLKAE
                     QLTFTLSWLPSH"
     gene            complement(18922..20601)
                     /locus_tag="VQ865_000561"
     CDS             complement(18922..20601)
                     /locus_tag="VQ865_000561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-L-fucosidase"
                     /protein_id="HET3134970.1"
                     /translation="MKKIKPHGPLPSQTQLAYLGDELAAFIHFGPNTFYDQEWGTGQE
                     DPERFNPSQLDAREWVRVLKETGFKKLILVVKHHDGFVLYPTAHTDYSVKVSPWRRGK
                     GDLLLEVSQAATEFDMDMGVYLSPWDAHSPLYHVDREADYNAYYLAQLKEILSNPNYG
                     NAGKFAEVWMDGARGEGAQKVNYEFEKWFETIRDLQGDCLIFSTEGTSIRWIGNERGY
                     AGDPLWQKVNPDKLGTEAELNYLQHGDPSGTIFSIGEADVSIRPGWFYHEDQDPKSLE
                     ELVEIYFHSVGRGTPLLLNIPPNQAGLFDAKDIERLYEFATYRNELYKEDLALGAEVS
                     GPALSADFACRHLTDGLETSSWANDADLPIQLELDLGSPKTFDVIELREDLKLGQRIS
                     AFHVQVEVDGVWQEFGRGFTVGHKRLLRGSLVEAQKVRVMITEAQSIPVLTKISLYKT
                     PGLSKKEVVQELAFAEKSLAVAKGENAYFTVKRRECSGPLEAKISIQPGTGVHGVAYQ
                     DEIYVLQFQAGESKKDLHLPTLYFAGDKTLDFYLNLTVDGQLVDQLQVQVS"
     gene            21357..22586
                     /gene="arcA"
                     /locus_tag="VQ865_000562"
     CDS             21357..22586
                     /gene="arcA"
                     /locus_tag="VQ865_000562"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HET3134971.1"
                     /translation="MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIP
                     FLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQT
                     KVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESEYPFAIDPMPNL
                     YFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIE
                     GGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDT
                     VFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIR
                     CGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVR
                     GRGGPRCMSMPFEREEV"
     gene            22644..23660
                     /gene="argF"
                     /locus_tag="VQ865_000563"
     CDS             22644..23660
                     /gene="argF"
                     /locus_tag="VQ865_000563"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HET3134972.1"
                     /translation="MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHY
                     LAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLV
                     YCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITED
                     ADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPA
                     FHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLY
                     IPKV"
     gene            23825..24772
                     /gene="arcC"
                     /locus_tag="VQ865_000564"
     CDS             23825..24772
                     /gene="arcC"
                     /locus_tag="VQ865_000564"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003025409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HET3134973.1"
                     /translation="MANRKIVVALGGNAILSSDPSAKAQQEALVETAKHLVKLIKNGD
                     DLIITHGNGPQVGNLLLQHLASDSEKNPAFPLDSLVAMTEGSIGFWLKNALQNALLDE
                     GIEKNVASVVTQVVVDKNDPAFVNLSKPIGPFYSEEEAKAEAEKSGATFKEDAGRGWR
                     KVVASPKPVDIKEIETIRTLLNSGQVVVAAGGGGIPVVKENNGHLTGVEAVIDKDFAS
                     QRLAELVDADLFIVLTGVDYVFVNYNKPNQEKLEHVNVAQLEEYIKQDQFAPGSMLPK
                     VEAAIAFVNGRPEGKAVITSLENLGALIESESGTIIEKG"
     gene            24983..26494
                     /locus_tag="VQ865_000565"
     CDS             24983..26494
                     /locus_tag="VQ865_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004191872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HET3134974.1"
                     /translation="MSEKAKKGFKMPSSYTVLLIIIAIMAVLTWFIPAGAFIEGIYET
                     QPQNPQGIWDVLMAPIRAMLGTHPEEGSLIKETSAAIDVAFFILMVGGFLGIVNKTGA
                     LDVGIASIVKKYKGREKMLILVLMPLFALGGTTYGMGEETMAFYPLLVPVMMAVGFDS
                     LTGVAIILLGSQIGCLASTLNPFATGIASATAGVGTGDGIVLRLIFWVTLTALSTWFV
                     YRYADKIQKDPTKSLVYSTRKEDLKHFNVEESSSVESTLSSKQKSVLFLFVLTFILMV
                     LSFIPWTDLGVTIFDDFNAWLTGLPVIGNIVGSSTSALGTWYFPEGAMLFAFMGILIG
                     VIYGLKEDKIISSFMNGAADLLSVALIVAIARGIQVIMNDGMITDTILNWGKEGLSGL
                     SSQVFIVVTYIFYLPMSFLIPSSSGLASATMGIMAPLGEFVNVRPSLIITAYQSASGV
                     LNLIAPTSGIVMGALALGRINIGTWWKFMGKLVVAIIVVTIALLLLGTFLPFL"
     gene            26516..27847
                     /locus_tag="VQ865_000566"
     CDS             26516..27847
                     /locus_tag="VQ865_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000686986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase"
                     /protein_id="HET3134975.1"
                     /translation="MKIDITNQVKDEFLISLKTLISYPSVLNEGENGTPFGQAIQDVL
                     EKTLEICRDIGFTTYLDPKGYYGYAEIGQGAELLAILCHLDVVPSGDEADWQTPPFEA
                     TIKDGWVFGRGVQDDKGPSLAALYAVKSLLDQGIQFKKRVRFIFGTDEETLWRCMARY
                     NTIEEQANMGFAPDSSFPLTYAEKGLLQVKLHGPGSDQLELEVGGAFNVVPDKANYQG
                     PLYEQVCNGLKETGYDYQSTEQTVTVLGVPKHAKDASQGINAVIRLATILAPLQEHPA
                     LSFLATQAGQDGTGRQIFGDIADEPSGHLSFNVAGLMINHERSEICIDIRTPVLADKE
                     ELVELLTRCAQNYQLRYEEFDYLAPLYVAKDSKLVSTLMQIYQEKTGDNSPAISSGGA
                     TFARTMPNCVAFGALFPGAKQTEHQANECAVLEDLYRAMDIYAEAVYRLAT"
     gene            27942..28069
                     /locus_tag="VQ865_000567"
                     /pseudo
     CDS             27942..28069
                     /locus_tag="VQ865_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001836165.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fucose isomerase"
     gene            complement(28252..28542)
                     /locus_tag="VQ865_000568"
     CDS             complement(28252..28542)
                     /locus_tag="VQ865_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000501069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134976.1"
                     /translation="MGALGYYEGFVPYVSNQYKNQAEEEGKPLSDKYIFEKILGKTYA
                     AFKKDQISERVEKLGKLKPITINYNGKSEVIDSKEKLQELMNKAVKDEVAQI"
     gene            complement(28530..28782)
                     /locus_tag="VQ865_000569"
                     /pseudo
     CDS             complement(28530..28782)
                     /locus_tag="VQ865_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657761.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif.; frameshifted; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
     gene            28986..29063
                     /locus_tag="VQ865_000570"
                     /pseudo
     CDS             28986..29063
                     /locus_tag="VQ865_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(29181..30065)
                     /locus_tag="VQ865_000571"
     CDS             complement(29181..30065)
                     /locus_tag="VQ865_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HET3134977.1"
                     /translation="MIFLIVCVLLLVIVTLSTVYVVRQQSVAIIERFGKYQKVANSGI
                     HIRLPFGIDSIAARIQLRLLQSDIVVETKTKDNVFVMMNVATQYRVNEQSVTDAYYKL
                     IRPESQIKSYIEDALRSSVPKLTLDELFEKKDEIALEVQHQVAEEMTTYGYIIVKTLI
                     TKVEPDAEVKQSMNEINAAQRKRVAAQELAEADKIKIVTAAEAEAEKDRLHGVGIAQQ
                     RKAIVDGLAESITELKEANVGMTEEQIMSILLTNQYLDTLNTFASKGNQTIFLPNTPN
                     GVDDIRTQILSALRAEKK"
     gene            complement(30210..31361)
                     /locus_tag="VQ865_000572"
     CDS             complement(30210..31361)
                     /locus_tag="VQ865_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HET3134978.1"
                     /translation="MATFYVPAVNLIGKGVVNEVGPYIKELGYKKALLVTDKYIEGSD
                     ILPKTLKPLDTEGIEYVIFSDVEPNPTCKNVTDGVAALQEHGCDFIISLGGGSPQDAA
                     SCISIMATNGGKPQDYEGLHKSAKKGLPVVAINTTAGTSAEITINYVITDEERKVKMV
                     MVDKNSLALISVNDPELMLSKPKGLTAATGMDALTHAVEALVTPGAYDVTKKLSIGAI
                     ELIKEYLPRAVENGHDIEAREGMVNAIFLGGMSFNNAGLGYVHSMAHQLGAVYNLPHG
                     VCCAMLLPVIERENAKRVPEAFRNVAKALGLHVEGKSDQECADYAIAEIEKLSETVGI
                     PKKLTELGIEEKDFDFEYLSKNALIDACAPGNPFMPTLEETIAFYKELF"
     gene            complement(31507..33273)
                     /locus_tag="VQ865_000573"
     CDS             complement(31507..33273)
                     /locus_tag="VQ865_000573"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HET3134979.1"
                     /translation="MIQHPRIGIRPTIDGRRQGVRESLEVQTMNMAKSVADLISSTLK
                     YPDGEPVECVISPSTIGRVPEAAASHELFKKSNVCATITVTPCWCYGSETMDMSPDIP
                     HAIWGFNGTERPGAVYLAAVLASHTQKGIPAFGIYGRDVQEANDTAIPEDVKEKLLRY
                     ARAALATGLMRDTAYLSMGSVSMGIGGSIVNPDFFQEYLGMRNESVDMTEFTRRMDRG
                     IYDPEEFERALKWVKENVKEGFDHNREDLVLSREEKDRQWEFVIKMFMIGRDLMVGNP
                     RLAELGFEEEAVGHHALVAGFQGQRQWTDHFPNGDFMETFLNTQFDWNGIRKPFVFAT
                     ENDSLNGVSMLFNYLLTNTPQIFADVRTYWSPEAVERVTGYTLEGRAAAGFLHLINSG
                     SCTLDGTGQATRDGKPVMKPFWELDESEVQAMLENTDFPPANREYFRGGGFSTRFLTK
                     GDMPVTMVRLNLLKGVGPVLQIAEGYTLELPEDVHHTLDNRTDPGWPTTWFAPRLTGK
                     GAFKSVYDVMNNWGANHGAITYGHIGADLITLASMLRIPVNMHNVPEEDIFRPKNWSL
                     FGTEDLESADYRACQLLGPLHK"
     gene            complement(33330..36446)
                     /locus_tag="VQ865_000574"
     CDS             complement(33330..36446)
                     /locus_tag="VQ865_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001031112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3134980.1"
                     /translation="MNKEKIKRKLITILFVCIGMLCFGLLAGVKADNRVQMRTTINNE
                     SPLLLSPLYGNDNGNGLWWGNTLKGAWEAIPEDVKPYAAIELHPAKVCKPTSCIPRDT
                     KELREWYVKMLEEAQSLNIPVFLVIMSAGERNTVPPEWLDEQFQKYSVLKGVLNIENY
                     WIYNNQLAPHSAKYLEVCAKYGAHFIWHDHEKWFWETIMNDPTFFEASQKYHKNLVLA
                     TKNTPIRDDAGTDSIVSGFWLSGLCDNWGSSTDTWKWWEKHYTNTFETGRARDMRSYA
                     SEPESMIAMEMMNVYTGGGTVYNFECAAYTFMTNDVPTPAFTKGIIPFFRHAIQNPAP
                     SKEEVVNRTKAVFWNGEGRISSLNGFYQGLYSNDETMPLYNNGRYHILPVIHEKIDKE
                     KISSIFPNAKILTKNSEELSSKVNYLNSLYPKLYEGDGYAQRVGNSWYIYNSNANINK
                     NQQVMLPMYTNNTKSLSLDLTPHTYAVVKENPNNLHILLNNYRTDKTAMWALSGNFDA
                     SKSWKKEELELANWISKNYSINPVDNDFRTTTLTLKGHTGHKPQINISGDKNHYTYTE
                     NWDENTHVYTITVNHNGMVEMSINTEGTGPVPFPTPDKFNDGNLNIAYAKPTTQSSVD
                     YNGDPNRAVDGNRNGNFNSGSVTHTRADNPSWWEVDLKKMDKVGLVKIYNRTDAETQR
                     LSNFDVILYDNNRNEVAKKHVNNLSGESVSLDFKEKGARYIKVKLLTSGVPLSLAEVE
                     VFRESDGKQSEEDIDKITEDKVVSTNKVATQSSTNYEGVAALAVDGNKDGDYGHHSVT
                     HTKADSNAWWQVDLGEEFTVSKVDIYNRTDAEPQRLSNFDVIFLSSSGEEVFRRHFDK
                     VVDGLLSLKVPSVGAKLVKIELKSAAIPLSLAEVEVYGSKRTPKKLSNIALTKETRQS
                     STDYNGFSRLAVDGNKNGDYGHHSVTHTKGDSPSWWEIDLAQTEELEKLIIYNRTDAE
                     IQRLSNFDIIIYDSNNHEVFKQHIDSLESNNLSIDLKGLKGKKVRISLRNAGIPLSLA
                     EVEVYTYK"
     gene            complement(36456..38750)
                     /locus_tag="VQ865_000575"
     CDS             complement(36456..38750)
                     /locus_tag="VQ865_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 95 protein"
                     /protein_id="HET3134981.1"
                     /translation="MKLWYKKAAANWNEALPIGNGHLGGMIYGSATKECIQLNDETIW
                     YRGKSDRNNPDSLLHLKKIREYLLDGEIQKAEELIKLTMFATPRDQSHYELLGELYIE
                     HIDIQSCALSLYERELDLDTAISNVVFEPNSCNLQIKREYFTSFNKNILCCRIVSSVQ
                     NTLNLNINLGRNKRFNDEVSKLDSSTILMSASAGGRKGVQFKVVCHSKVTDGEVSVLG
                     ETIVIRNATEVFLYLKSMTDYWGNIDISSLQGEFSSIDYFTEKDEHVKKYQEQFNRVD
                     FKLDYSKGCLSIPTNLLLENTKKYSNYLTNLLFHYGRYLLISSSQPNGLPANLQGIWC
                     DELNPIWGSKYTININTQMNYWMVGPCDLPEVEYPLFDMLERMREPGRLTAKKMYGAR
                     GFTAHHNTDGFGDTAPQSHAMGAAIWVLTIPWLCTHIWEHYLYFQDERILTEHFEMIK
                     EAFLFFEDYLFEVDGYLMTGPSVSPENKYRLKNGIEGNACLSSTIDNQILRYFCDSCI
                     GIAKQLGDNSDFISRVKELKKKLPKTKIGSNGQIQEWLEDYEEVEPGHRHISPLFGLY
                     PYNEIDIHKTPELAEAAKITINRRLSNANFLSSQEREQAINNWLVSGLHASTQTGWSA
                     AWLIHFFARLYQGEPAYNQINGLLNNATLGNLFLDHPPFQIDGNLGLVSGICELLVQS
                     HHNWLSLIPALPSAWSEGEVKGFRVRGGYKVSFAWKNGDITFLKLEGGNKDQKVRVRI
                     YGKNTDVQNIELVFNSEKIIELNF"
     gene            complement(38809..39609)
                     /locus_tag="VQ865_000576"
     CDS             complement(38809..39609)
                     /locus_tag="VQ865_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3134982.1"
                     /translation="MMNNKVTKVELKKVFKRSFMYGSSWNYERMQNLGFLYTILPVLK
                     KLYPDKDSASPAMKRHLEFFNTHQTAAPFILGVTSAMEEQEGNEGAASITGIKVGLMG
                     PLAGLGDSLFWLTLVPICFSIGASYSKDGGALGIFIALILFNIINIPVKYFGLKYGYT
                     KGSSLIQENNTKGTLNRVTSMATALGLVLVGGLIPSMVGINFGLEFKQGELVISVQEM
                     ITKLIPGFIPMALTLLMCKLIRKGKNPVVLIFSVMAIGVILVVLGILK"
     gene            complement(39606..40379)
                     /locus_tag="VQ865_000577"
     CDS             complement(39606..40379)
                     /locus_tag="VQ865_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000899624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3134983.1"
                     /translation="MLFTQALLVTLVGIIATIDYNGPLFMIHRPLVTSAMVGLVLGDF
                     TQGVLIGSALELTWLGVTGIGGYTPPDTISGAIIGTAFGILSGQGETAGIAIAVPIAV
                     ATQQLDVLAKTLDVYFVKKADNDAKNGDYSKIGFYHYSSLVLITLFKIVPIFLAIMLG
                     GEYVADLFAKVPPIVMQGLNSAGALLPSIGFGMLLNMMLKKNMWVFLLIGFICSVYGG
                     MSTIGISLVGIAVAYFYDMIGSKPQETTSSSDVEEDLDL"
     gene            complement(40404..40874)
                     /locus_tag="VQ865_000578"
     CDS             complement(40404..40874)
                     /locus_tag="VQ865_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000020992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3134984.1"
                     /translation="MSIEFVRIDDRLVHGQVVTTWLKKYDIEQVIIVNDRISEDKTRQ
                     SILKISAPVGLKIVFFSVKRFVEVLNSVPIKKRTMLIYTNPKDVYDSIEGNLKLEYLN
                     VGQMSKTEENEKVTGGVALGEEDKYYFKKIVDKGTRVEIQMVPNDKVTMLEKFL"
     gene            complement(40865..41296)
                     /locus_tag="VQ865_000579"
     CDS             complement(40865..41296)
                     /locus_tag="VQ865_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000483177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3134985.1"
                     /translation="MFNRGILVASHGNFASGALMTAEMFVGETTNDRVRTLGLMPGEN
                     IVEFEHYFKNQVNELLDSNQEVIVLTDLIGGSPNNVALSRFLNLDSVDIVTGFNIPLL
                     VELISSYDSKINLEEIVQNAQNSLFNVKQQLNVEEEEDLCL"
     gene            complement(41289..41729)
                     /locus_tag="VQ865_000580"
     CDS             complement(41289..41729)
                     /locus_tag="VQ865_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000912112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RbsD/FucU family protein"
                     /protein_id="HET3134986.1"
                     /translation="MLKHIPKNISPDLLKTLMEMGHGDEIVLADANYPSASCANKLIR
                     CDGVNIPELLDSILYLMPLDSYVDSSIQFMNVVSGDDIPKIWGTYRQMIEGHGTDLKT
                     ITYLRREDFYERSKKAYAIVATGETSLYANIILKKGVVVERENV"
     gene            complement(41741..42379)
                     /locus_tag="VQ865_000581"
     CDS             complement(41741..42379)
                     /locus_tag="VQ865_000581"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HET3134987.1"
                     /translation="MSDVKQELIKYGKKLVETDLTKGTGGNLSVFDREKQLMAITPSG
                     IDFFEIKESDIVVMDINGNVVEGERLPSSEWYMHLIQYQTRDDIDAIIHAHTTYATVL
                     ACLREPLPASHYMIAVAGKDVRVAEYATYGTKELAVNAAKAMEGRRAVLLANHGILAG
                     AQNLLNAFNIVEEVEYCAKIYCLAKNFGEPVVLPDEEMELMAEKFKTYGQRK"
     gene            complement(42494..43897)
                     /locus_tag="VQ865_000582"
     CDS             complement(42494..43897)
                     /locus_tag="VQ865_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000388528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HET3134988.1"
                     /translation="MEAVLAIDLGATSGRAIVGYLSENKLVMEEINRFSNLPIRVKGH
                     LSWDIDFLLAKILESIRLANTSYKILSIGIDTWGVDFGLIDNEGKLLLQPVHYRDERT
                     KGVLKEISEMTELEKLYSETGNQIMEINTLFQLFKARQESPDSFYKTNKILLMPDLFN
                     YLLTGKFATEKSIASTTQLFDPRSQNWNQNILKLFELDSSLLPEIVSEGNVLGRIKKE
                     YGLGDIPVVNVCSHDTASAIVSVPKTEGSLFISSGTWSLVGVELTSPLLTTESFSYGF
                     TNEVGKDGVITFLKNCTGLWIIEELRRSFERRGKAYSFDDIRTMVEKEKENLPLIDTE
                     STEFATESDMHKTLTEYLAYHHETREWTDGQLFKIVYESLAETYRKAIELLEELTHKV
                     YKRIYVIGGGARASYFNQMIADRTGKEVLTGLTEATAVGNIVVQLIAMGQLKGMEEAH
                     HVIEEFLQLESYYSQKN"
     gene            44073..44846
                     /locus_tag="VQ865_000583"
     CDS             44073..44846
                     /locus_tag="VQ865_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3134989.1"
                     /translation="MIKDERVLELIEIIKKKKRIAVKELAEITFSSTSTLRRDLIFLE
                     NQGLIKRKHGYVTLSSMNTIELSHQIREGESTRQKRLIASLAKDFIRSGMCVYLDSST
                     TVYELCPYLSELDNLIIFTNGLHTAQTLSETVKDSSKIFITSGEVKHQSCSVVNYDKE
                     NSLLDHFNIDLAFCSARGIDDQYVYEASLSQAISKKNIIDKAHETILLIDSSKFYKTG
                     FFKINPLSKYTTFISDTVPDQKLLDAVELFDGEWVSDIQ"
BASE COUNT        13590 a         9877 c         7939 g        13859 t
ORIGIN      
        1 aaccatacct acggcaaggc gacgttgacg tgatttgaag agattttcga gtatgagttt
       61 attttttacc tgacttgtcc atattccaga agtctgtcac ggctccgcgt gaagcagatg
      121 atacgatgtg ggcatattta ccgaggacac cacggctgta aagtggtggc aaggttgttt
      181 ctgccttgcg tttttcaagt tcttcttcgg atacggccat ggaaatttct ttggtatctt
      241 ggtcaaccgt aacgatatcg ccggtacgga gataggcaat tggtccacca tcctgagctt
      301 caggagcgat atgtccaaca accagaccat aagtaccacc agagaaacgt ccgtccgtca
      361 agagggccac cttatctccc tgacctttac caacaatcat tgaagaaagt gacagcatct
      421 caggcatacc aggaccacct ttaggtccaa caaaacgaac aacgactaca tcgccatcaa
      481 cgatttcatc tgtcagaacg gcctgaatcg catcttcttc tgagtcaaag accttagctg
      541 gcccaacgtg acgacgcact ttaacacctg ataccttggc aactgcaccg tcaggagcaa
      601 ggttcccgtt caagatgata agcggaccat ccgcacgttt tggattttca agtggcatga
      661 taactttttg gcctggagtc aagtctgcaa agtcagccaa gttttcagct acagtcttac
      721 cagtacatgt gatgcgatct ccgtgaagga aaccatttgc caacaagtac ttcataaccg
      781 cagggacacc accgacttcg tagaggtctt ggaagacata ctgaccagat ggtttcaagt
      841 cggccaagtg aggcacacgt tcttgaatcg tattgaagtc ctcaagtgac aagtcaacat
      901 ttgcggcatg ggcaatggcg agcaagtgaa gagtggcgtt tgtagaacca ccgagagcca
      961 tcgttacagt gatagcatct tcaaaggctt cacgagtcaa gatatctgat ggtttgagac
     1021 caagttccaa catcttaaca acagcacgtc ctgctgcttc gatatcttct ttcttatcag
     1081 ctgattcagc tgggtgagag gatgaccctg gcaaactcat ccctagaact tcgatagcag
     1141 ttgccatggt attagcagta tacataccac cacaaccacc agggccaggg caggcattac
     1201 attcaagacg tttcacgtcc tcagctgtca tgtcaccgtg gttccatttt ccgatacctt
     1261 caaagacaga aaccaagtcg atatctttac catcaagatt tcccggtgca atagttccac
     1321 cataggcgaa aatggctggg atatccatgt tggcaatagc aatcatagat ccaggcatgt
     1381 tcttgtcaca gccaccgata gcgacaaagg catcgacgtt gtgaccactc atagccgcct
     1441 cgatggagtc cgcgataatg tcacgagatg ttagagagaa acgcatacca ggcgttccca
     1501 tagcgatccc gtctgctacg gtaatggttc caaactgtac aggccaagcg cctgcagatt
     1561 tgacaccttc tttagccagt ttcccgaaat catgcaagtg aatgttacat ggtgtatttt
     1621 ctgcccaagt cgaaatcact cccacaatcg gtgtttcaaa gtccttatct gtcataccag
     1681 tcgcacgaag catagcacgg ttaggtgatt taaccatgct gtcataaatg ctactgcggt
     1741 gacgtttatc taattcagtc atcttatccc tcccatttca gtttttacta ttatagcaca
     1801 atttaaaggc aatgaacaga ataaaattct tgaattttca gaaaattcta tacgcatgtg
     1861 aaatatttaa aattaaaaac aacaaagcgg attagtgcac tttctgatga ccagaatatg
     1921 ctttttaatc cgctttcttt aaataacgta ctgtaatttt tacagaaatt ctttcaaata
     1981 agtgtattta acatctatct tgcattataa atttctagaa ccttctcttt tatattcgat
     2041 tcactcaaac catactcatt aagaagataa tccattttcc ctacttgacc aaatctttct
     2101 tgaacaccca tccgatgaat ttttgttatt ccatcatcag agaataattc acatacagca
     2161 ctgccaattc cacctatctg attgtggttt tctacagtaa atatagtttt tccacttaac
     2221 attgttttta tctgttctgg tatcggtttg attctaaata aatctatcac acctactgaa
     2281 taacctaatt tagacagttc atctgcaact cgaatacttg gagcaaccat tatgccagaa
     2341 gcaacgatta caacatcttc accatgcctt aactcaatgt agcctttaga aaaatcttct
     2401 ccaccttgat acacaggaac tggagctttt ctaattgttc gaatatattt tagtcctttt
     2461 aagtctaatg tctggttcaa tatttcacga aattggatat catcagttgc ttcaaaaatg
     2521 atcgatttag gaattaaacg taacaatcca atttcttcaa atggcatatg tgtcccacca
     2581 ttcatttctg cagttactcc tgcatctgat ccaatcacag tggcatccaa ttgtgcgtat
     2641 ccaagagaaa taaataattg atcaaatact cttcgtgaag caaaaggacc aaatgtatga
     2701 agataaggtc taaacccctg aatagacaag cctgctgcaa ggccgaccat ttctgcttcc
     2761 ataatcccaa cattcacata acggtctcca aagtcctttt caagattatg agtagccatc
     2821 gaacttgaca aatcggcttc taagactact atatcagaat cactttgatt agcctctaaa
     2881 aggaagtctc tatatacatg ccgtaattct ttcgtacttc tcatcattct gtttcctcca
     2941 attcctgact taatctttct acaactgaag ttaacatttg tttctcctct acagtagggc
     3001 gaagatgatg attggatttc atttcttcca gctcttgaac cccttgacct ttaatagtat
     3061 ctaatacaat gcacttaggt gatgaattat ttgactgttt taattggaca atcccttcat
     3121 aaatttctct aatatctgaa cctttgaccc taatggattc aaatccaaat gctgaaaatt
     3181 tttctacgaa atcacctgaa ttacaaatat cctttgtaaa accatctaat tgttttttgt
     3241 tatcatcaac aaatacaatt aagttggata actgttgatg agaagcaaac tgtatagcct
     3301 cccaacattg tccctcattt aactcaccat ctccaacaat agcgtaagta taaaagggac
     3361 tctttcttat tctctgacca tatgcaagtc cagttgcaac actaattcct tgtcctaaag
     3421 agcccgttgt catatctatg cctggcgtta gatttctatc aggatgagac ggtaatttgg
     3481 ttccatttgt atttaaagaa tataagaatt ctttgtcaaa gaaaccattc aaatagagtg
     3541 tactgtatag agctggtcct ccatgacctt ttgataatat gaaataatct ctatctcgtg
     3601 ctgcaaatat ttctggagtc attggcatta tttcaccata aagcactgct aacacttcta
     3661 cgatagacaa acttcctccg taatgtccga atccaagatg attcaatgtt ctaagagtat
     3721 ttaatcggat gttagtcgca aattttctta acccatcttc tctattttta cttaaaatca
     3781 tcccttattc ctcctttgca gatggctttt taataaagga tactccaaac ataactgcta
     3841 aaataagaac aagaccaatc acaatgcctg cttgtgagcc aaattgattt aacattccta
     3901 aaataattcc tgatagacca aaatctgcat ctgagaaagt tgatccttgg aaaccaagtc
     3961 ctcccaaaac tggcattaaa aagactggaa gaaaactgat taaaatacct tgtaaaaatg
     4021 ctccaatagt ggctccacga acaccaccag atgcattccc aatgacacct gcagtcgctc
     4081 cacagaagaa atgaggcaca acgcctggta agataacaac cgttcctgaa gcaatcataa
     4141 ttgccatact tactaaacca ccaacaaaac tagagataaa tccaattaga actgcattgg
     4201 gtgcataagt ataaacaatc ggacaatcca aagcaggttt tgaattaggt acaagacgct
     4261 ctgaaatacc tttaaaggct ggaacaattt cgcccaaaat aaggcgaaca cctgctaaaa
     4321 taacaaatac ccctgctgca aattgacctg ctaattgtaa agcataaact agaccacttg
     4381 taccactact gatttctttt tctatatatt ctgaccctgc aaagatagct acaataatgt
     4441 aaataactgc catggataaa gtgatactaa cagtactatc acgtaaaaaa gctaaactct
     4501 ttggaaattt aatgtcctct gttgattttg atttgtcacc gataaggcta ccagtaaaac
     4561 cactcaacca atatcccaaa gaactgaaat gacctaaagc taccttgtca tttccagtta
     4621 attgaaccat atatttttgc acaaatgctg gggaaatact cataataata ccgagtgcta
     4681 atcctcctag taagataaga ggcaagctag taaagccagc aactgataaa atgaccgcaa
     4741 tcatacatgc catatataga gtgtggtgcc ctgttaaaaa aatatattta aatcgagtaa
     4801 aacgagcgat taagatattg aacaccatgc ctgcaaacat aatcattgca gtagctgagc
     4861 catatgttgt taaagctaca gctacaattg cttcattatt cggcacaacg ccagataaat
     4921 gaaaagcatg ctcaaacatg gtaccaaatg gatttaaaga attttgtaca attcctgcac
     4981 caccagatac aactaagaaa ccaacaaagg tcttaattcc acctttaata atatcaggta
     5041 atttcttctt ctgaagaact aatcctaaaa ttgcaattaa agctactaaa atagctggtg
     5101 tactaacaat atccaatatg aacttcatca tgacgctagc ctcctatata agtccttttt
     5161 cttcacaaag tttagtaatt aattctcgta gttcatccat atcaataata ctatttaaga
     5221 tacgaacatc tccaagatga ctagctgaat cagctagatc acgaccaaca atccaaatat
     5281 cagctgcatt tggatctgct ccacctaaat cataatgttc aacttctaca tccgaaacat
     5341 tcaaatcact caatacagat tcaatattca tctgtaccat aaaacttgaa cctaatcctg
     5401 aaccacaagc tgtaccaatt tttaacatta tctaatcctc ctgtttaatt atcattttaa
     5461 tgtcatcata gttttttgat gatattaaag tttgaacatg atttttatct cttaaaattg
     5521 ttgttaaatg tgacaaagcc tttaaatgac tctcattatc aatggctgca atacaaatca
     5581 acaatcttac ctcttgttct ggattatcca ataaataaat cggttcttcc aaaactaaca
     5641 ttgacattcc tatttcattc acaccttcat ctggccgagc gtgaggaatt gctactccct
     5701 tccctaaatt aataaaaggt ccaaactctt ctactttttg aatcattgcc tcagggtagt
     5761 tctcagttat cttatcttga tccaaaagcg gtttagctgc taaacgaatc gcctccttcc
     5821 atcctaattt ttgcgaacta acctgatagg tttctttggt aataagttgt tctagcactg
     5881 gtacaatttc ctttctatca tttttttgat aaagataatt ctttaacgcc aatcttaatt
     5941 ccaattcttg tgtaataatt ccatatcttt tgacaatatt caggatttgt tcaatctcaa
     6001 aatctccata ctctaaattc ggaaaatctt ttaacactag ttctactagt tgtattgctt
     6061 gctcttcagt catcataacc gaaactagat aatttggctt ttctgtctcc acctttatgg
     6121 tagaaaaaac catatcatag tcactactag ctttcacctg taaatcatca atctttgagg
     6181 ttcctataaa ctcaatttga ggaaataatg ctaatagatt ctcttttaac atcaatgaag
     6241 aactaacacc attaggacaa atgattgctg ctttatagca tttttgaggc aaagtatctg
     6301 ctttctttaa ataacctccg aaatggataa caaaatatgc tgtttcacta tcaggtatgg
     6361 gattgtcaat agcgtccatc aagggcatca aagaatcttt gactaattca aataaatcag
     6421 gataatgttc tttaacatgc aatacatatt catttgaact aggtaggccg aactttaatc
     6481 tatagtaagc cggtataagg tggcggcgaa gattttctct caatccttcc ctttgtttaa
     6541 aatgtaacaa agaaatatct tccattctac ttataatagc ctctgttaat tgattaaagt
     6601 aaaccggagc aacatctact tcaccttcaa agcaacttga taataaaact gtgatatagc
     6661 gataatcatc ctcagaaaac accgtatcta taattcccaa atcaaccact gtatccaata
     6721 aaatagtggt tatatcttga ataacaggag atactaatgt ctctgaaaga catactcttt
     6781 caacatccct ttgataccta cacagaatga atactaaacc gaaaaggcaa acttttaatt
     6841 gattaacaat aggtactagc tgtagcttct cataataatc tttaactacc tgatttatca
     6901 aatcataagt taatgaatac ccccaactgg ataaaacata atccaaaccc caaatcccta
     6961 tggaggattc cagcaactca ctaaccattt gaaaagctaa gcggtgctta ttccactctg
     7021 aaccgtgtaa agtataacct tttgctctac tgtaccctag ctccaaatca ttatctaaca
     7081 taatctttct taatgattga atatcagata aggttgtatt cttacttact ttcaaaaagt
     7141 cttggtaatg attattcgat ataaaatcta atcggcaaaa agtgtaaaga tagattaaag
     7201 ctaagcgagt cgactttggt aaaaccaatt catccgactt aataatatct gtcaaagact
     7261 gcttcgtacg atttgataaa ctatagcgac cttgcttttt atccagcact atccctttat
     7321 tagctagata aggcactaaa taatctattc cttctttgac ttcctttata ggtaagctca
     7381 ccttaacaga taattcatat aatgatagct cacaatgatc catcaaagtc atcaaaataa
     7441 ctagtgctct ataatcaaac atttctcttc ctttctaact acaattatag tgtaaaagtt
     7501 ataagaataa aagagtattt gagcacaata taatctcacc ttttaaaaga aattattggg
     7561 ctgaaagttt ttagtgatta ttttcaactt tctattgact tttaaaaaca aagtgatatc
     7621 atttagatat caaataatgg gaggtcattc ttatgactga aaaactaatc aattcaaaac
     7681 caaatggtgt attcgcattg attctcattg agttgacaat cgtacttggt atctttatat
     7741 ttataatggg tgttggttcg gaaaacattt ttggaattat tatcggacct ttactaatcg
     7801 taattgcagg tctagctcat gctggtttaa aagttgtcaa acctcaggaa gctctggttc
     7861 tgacactctt tggtaattat acaggtacca tcaaagaacc tggtttttac tttgtcaatc
     7921 ccttcagcgt agcagtcaac cctgcaaacc acactcgact tggacaaagt ggtgatgtta
     7981 gcacaaaatc tcctttttta ggagctaaat catcaaatga caatgatgta aatcttgaaa
     8041 ttggcaagaa acacatttcc ctcaaagtca tgaccttgag caattctcgt caaaaaatca
     8101 atgattgctt aggaaaccct gtagaaatcg gtatcgcggt aacttggaga gttgtcgata
     8161 ccgctaaggc agtcttcaac gttgataact acaaagaata tctttcattg caatgtgata
     8221 gcgccctccg taatattgtc cgcatctatc cttacgatgt gtctcctaat gtggatacta
     8281 cgggtgacgg gcaagcagat gaaggtagtc tccgtggctc tagcgaaatt gttgctaacc
     8341 gtattcgtga ggaaattcaa agtcgcgtag aagatgctgg cttggaaatc cttgaagcac
     8401 gtatcactta cctagcttat gctccagaaa ttgctgccgt tatgcttcaa cgccaacaag
     8461 catctgccat tattgatgca cggaagatga ttgtagatgg tgctgtagga atggttgaaa
     8521 tggcactaga acggctcaat gaaggggaat tggtagaact tgacgaagaa cgaaaagctg
     8581 ccatggtttc aaatctcctt gtcgttcttt gtggcaatca tgatgcacaa ccaattgtca
     8641 acacaggaag tctttactaa agatggctga agctaaaaaa aagcagatcc cccttcgact
     8701 ctcaacaaag ttatacgctg cactcgcatc atgggcagaa gacgactttc gttcagtcaa
     8761 tgggcaaatc gaatatctcc tcacagagtg tgtcaagcaa cggaaaaaag acggaaaata
     8821 cgtatcagaa accattgacg aaccatttga gattgatatt taacaccttc tcctgtctgc
     8881 cgtgtcggat aggagaattt tttcatcttt ttttgtcaag taactttact ttacaaaaaa
     8941 aatgtgttat cctagtatgg ttgatgaaaa tcagtagatt gaatcgaata taaataccta
     9001 aaggagaaat caaaatggca gtacctgcac gtcgcacttc aaaagcgaag aaaaacaaac
     9061 gtcgtacaca ctacaaagta acagctccat ctgtaaactt tgacgaaact actggagatt
     9121 actcacgttc tcaccgtgta tcacttaaag gatactacaa aggacgtaaa atcgctaaag
     9181 ctgcatcagc tgaataatag aagggagata ccatgcgcgt aaatattaca cttgaacaca
     9241 aagaatctgg tgaacgcttg taccttactt ctaaaaacaa acgtaacact ccagaccgcc
     9301 ttcaattgaa gaaatactca ccaaaacttc gcaaacacgt tgtgtttaca gaagtgaagt
     9361 aagcattcaa tacgaatcaa tacagaagaa aaacgcttga tcagcgtttt ttctttttgt
     9421 taatttcact atattgcaag ggaaatcatt cgaatgacta cattattgat aatatttgtt
     9481 aagccatcaa aagtaattaa catttcatag cgagtaatcc tatttaaact cgtcccacta
     9541 tctatttctt cttatctctg tgttataatc ccgactttat cataagtttg tctaactgta
     9601 gcatttgaaa ccagataatt cttctgtttc acgcgaaaca ccctgcgcca agcaaggtgt
     9661 tcttgttttt atactcaatg aaaatcaaag agcaaactag gaagctagct gcaggctgct
     9721 caaaacactg ttttgaggtt gtagatggaa gctgacgtgg tttgaagaga ttttcgaaga
     9781 gtattaagtc gtataaatca tcgaagctgt cgcaatggta tgccactggt tagctgtagt
     9841 tgctgcgaaa tccttgtctg cgtagaagtc agtaaatggt aggatttcaa cttccagctc
     9901 gtcgatgcgg tcaagctggc cagccagata aacctcgata cggctttctg ctcgtttgat
     9961 gcgttgcaag agtccgccca tacggatgtc aactgtatcc aaaccaaaga ccttgttttc
    10021 tttcagccat tggtgactaa agagggcatg gaagtcttca atttggcttc taagttctgg
    10081 taattcttgt ctggcgattt gttgtaaact ttctttatca tccgcttggt aggcctgacg
    10141 aatgcgtcgt cccacatcta ctttgctact taaaatagca ttcaactggg cctgagtttc
    10201 aaagagataa gcatagtttc cagctttttc tttaatgtta gcaagcgtct cagcagcctg
    10261 agcgaagtgt ggcttgtcct gttcaggtgt catgtgtcgg tcaagtatcg gacagagaac
    10321 atcctgataa aagacatagc ggttgggatt gatgccactg agattacctg gtaggtctgg
    10381 taagaggttg gcaagatcaa tctgcataaa atcctcaacc gttagaccag tattggtctt
    10441 gaaatgcgca gacaaactat ctaggtcatt gcgatagctg agttctgccc agatttgcaa
    10501 gcttggtagg atagagaact gggcagtttc accaccattg tctccccaac ccgttacgat
    10561 gacttcttta atctgattgg cacggcaggc tttattagcc tcgatagcca ctagacggct
    10621 aaaatggttg tgaggtgtaa agccaatcca cttccaagct ccccctgcaa atgcaaggtc
    10681 atggctaatc ttgtgatgat tgcggaaatt acggttgtat ttttcctcgc tatcctgata
    10741 ataatcccag taaaccagag tcacacggtc tttgagacgg tctaggtaga cacgagtttc
    10801 ctctggaatt tccacatcac ggtcgtactg gccatccgct gacatgagtt tgaagaacat
    10861 atcactccac atctggcagt ggaaaccata tttgtcagca atatccagca cgcgctccaa
    10921 gtgttggcac atgaggagac tacgatccac aacaccgttc aaaatcaggt agcgtcccaa
    10981 accaaccaag tgggcttcgt ccatcccgat attgaccttg cgagtcttca gtttagacaa
    11041 cgtggcaaac atgccatcaa tcaggtcata aaccttttct tcgccaatga gaagaatgtc
    11101 ctctacatca cggagctcct gcacttcctt gacaccccat ttgacaaagg ccgacaagtg
    11161 ggccaaggtc tggatgcatg gtacaaaggt catgtcaaac tgttgggcat aggcttcgat
    11221 ttcctgcaac tcctctgctg aataagctcc acggaaatag ccaaagtaag gctgcccttc
    11281 aatctggtaa gtgtcttcca tgtaaagctc aaaggttgag tagcccatga gagccaagac
    11341 ctcaatcatc tgcttggcag aagccacatt cagcaccgca tttcgagaac agtcaaccat
    11401 gtaagccaaa tcttcgtaag ctgcttgttc ctcaatctct actttatcag cttctgctag
    11461 aactgttacc aacaaggata aggcacgata aagttggtga ggtttgcggt aggtcaattg
    11521 atagtgacct tcctcaccct cgatagagat agaggcttgg tcagactgag tgacagccac
    11581 ttccacatct ggtagagaaa tgtgaccttt taaaacctca atagcttgcg tttgtttggg
    11641 actaagtcct gtaaatctta ccattgcttt tcctcctgta gccagttgac aagagcaccg
    11701 tagagattgg catctgcgtg ataggtgcag gcctggataa ctggtgcgac cgtgtattct
    11761 tcgtaggtat cgacaaagtt atcaacagcc ttcttgacat cttggataaa atctggattt
    11821 tgactgatag agccacccag actgatgaca tctggatcga tgagatactg gatattgagc
    11881 aagccttgcg ccagattgcg gttcatgcgc tcaatggctt cttgacaaag agcattacca
    11941 gctgcggcct cttggtaaat cttgcgaccg tcccaatcag tatgaccaga tttttcaatc
    12001 acgtatcgta ccatattccc agttgatgct agttgcgacc agttattaag tttttcagca
    12061 ggggcaaggg ttgtcatgta gccaaattct ccacccagac cgtggcgacc tcgatgaagt
    12121 ctaccattga taatcatggc tccgccaatc cctgtcccaa tcacgacaca ggctgcattt
    12181 tcaagctctg gatgagctag tagttcactg agtccaacgc agttggcatc attttctaaa
    12241 tggacaggta gctgataaga gctaagcgcc tcataccaag aaaagccatg gatgtagggc
    12301 accgcactga agccatcaat cacacctgtc tcttgattga ccgcacctgg aacgctcata
    12361 gcaatcccac tgtaatcctg ttctgacaag cgttgatcta gccacgctag taaatcctcc
    12421 aagttttcag gcgttgaaat acttgtctta tacagtattt tcccatcagg agtcagactg
    12481 gcaaacttaa tcccagtccc tccgatatca atcgttgcaa tggtcattgt ttttaccata
    12541 aaaaggggcg aatcagcagt tagttcttac tttttcgccc ctcctttctt ttgatgttta
    12601 ctttttgaaa ttaaatttct tcttttttga tgaattctgt acgaatctct tgtggatcca
    12661 atggtcctga atgaactgga tatggtcgct caagtaagtc aagaatggtt tgttgatgtt
    12721 ctgatatgcg cacattttct tgactcatat tatagtaacg gaagacatag ccttcttcat
    12781 tttccgccac tttaaaggct gttggacaaa cttgcggtat gctgagaaca gaatggctca
    12841 agaggctacc agtcgcaacc acgcttcctt cctgtctagc aagctgaagg ctggtaaacg
    12901 gtgtctgcaa ggctttggca cgacggaaag ctgaaaagcg ttcttgggct tggtggcatt
    12961 caagtgcaaa ctcgacttca aactcacgca agcattgtgc ttctggcgtt gggaagtagc
    13021 cccagtcacc tagctcacct gatgcacgca aaatggtcac ggcaatggtg ttatccccaa
    13081 ggatttcgta ttcattcaat cccttattgg atacagtcac ccctttttca tcgtcataca
    13141 gactgacaaa agcttgttgg tgttgaggat tttcaggatt ttcccatgaa gcagctggtt
    13201 tgtttggtcg tgtcaccacc tcatagatac tttcagaatc attgcttgga cgcgtgttat
    13261 gagtcttgac caagagacgg atacggtgat ccttggcagt gttagtaaag cgagtcttga
    13321 agcggatttg tggattgtca acgaagacag tcaactcagt ttccagagga atgtttgtca
    13381 attcttctga ccgtccagcc tcacgcttca taaactcgat gataccttgt tgctcttctt
    13441 ctagcttttc atccgcactg acaggcacgg tcaattcatg tttgagcaag attttagcat
    13501 agcgatctgt gttttccaag acctcgtggc ccttaagctc tgcaaagatt ggctctgttc
    13561 cttttggttg gaaatagata tactcgtttc cgatgtcccc acggtcttcg aagcggataa
    13621 agtcttcata ggcttcgtga gttgtcttgt catatactgt gatgttgtca tccacactca
    13681 ccgttacgaa tggtgtatca atcactccgt tttggtaaat accctcacgg tgttcttgtt
    13741 ttccttccag caattggaag gttgtccaag aaagcggcgc taggtgaact ggaatggtca
    13801 cgcgcacttg tcgagcaata cgagcttggc ggaacttgtc ttttggtaaa tcgtactcaa
    13861 aattagctcc gaggtcttcg attgtagcct ctacaggatg accatccaag tcctccacac
    13921 ggtaacttgg caagataaga gcagccatct ttttgtagcc ttctgttggg tgcaattcct
    13981 tgaaatcaca agtcgccaca tcaatcactg tgctgacagt atcgacctta tcatgcaagc
    14041 ctgtgttaat gacagtaaag agatagtcac tttgagcctt atccgtagca attttaccct
    14101 tccactcgtt gagcaaatta cttttaacaa agtttcctac ttggttgacc ttggcaaaac
    14161 gcgtttccat ctcgcggtga acttcgtcca cgctacagcc acagatacta tcatgtggcg
    14221 cattctgcaa aagtgttttc caagcatagg tcaactggtc cttgtggttg tgtccaccag
    14281 tgataatagt caagggttct accacttgct ctaggaggtt gctattttct tggaaggctt
    14341 gttttaggta aatgcgggat gaagaagtgt tggcaagtgt gtaccagcca tctgtttcct
    14401 gactggtcaa ctcgcctgta acagttgata agtgttcagg aagcgcacct tctacagctt
    14461 gaacatattc atcaaaagaa ctatgaacaa agattacatc tgggaagagt tcatttgcca
    14521 cacgaatggc ttcgctcaga tttttctgta caggctggtg gtcacagccg ttcatcatca
    14581 accattggtt ggtcgaagcg taggcacgca catctgacaa tttttgtttc cagaaggtca
    14641 aggcctcatc tttgtcaact gggatttcat tcccattact gtaccagtta gcaaagagaa
    14701 tacctaaaac acgactacca tccacaccct gccagtacat ttctgaaaac tgggatgtaa
    14761 actgctcatc ttcaaggact tggttgtcaa atccaatcgg cttcacacca cgaccaaagg
    14821 ccgccacgtg aatgcctgat ttttgaagaa tttgaggcgc ttgtcccata tttccaaagg
    14881 tatctggaaa gtagccaatc tgggttgatt taccccattt ggcagcttct tgttgaccaa
    14941 tcaaggtatt gcggacattg gcttcactgg agatcaagta gtcatcctgc aagatgtaaa
    15001 agggaccaat tttaagtttg ccctcgtcaa tgtagcgttg gaccttgtcg cgattttcag
    15061 ggcgaatttg taagtagtca tcaaggacaa tagtttgtcc atccaagtgg aaactcttga
    15121 actcagggtc attttcaaag agatcaaaga gattgtcaaa caattccacc aactgcatac
    15181 gatggctttc aaaaggcaag taccactcac ggtcccagtg actatgtgag ataatatgta
    15241 caacaacatt ttccatgaag taaaacctca ttctaaattt aaattttaac gttttaaatg
    15301 taaacttgtg attctgataa gaatcggttg agctaaagcg agccccttag cgaatatcca
    15361 agtaatccaa gaccaactca cagaacatca tgttagccca ggagaaccat tcacgagagt
    15421 agagggtcgg atcatctaca tgaaagcttt cgtgcatgac acctgtacca ccatcgcagg
    15481 caaccagctg atccagcaag aattttttct ctgccttatc tcttgttgtc aatccttgga
    15541 tagaaagggc gattggccag atatagcgat agaaggtatg agaacttccg agaccgctag
    15601 cgtattctcc ttggtagaaa tatggatttt cagagctcaa aatggtacga cgagtagctt
    15661 gatacacttc atcatcgacc gaacagtagc ccagataggg cgcagctagt agacttggta
    15721 catttggatc atccatgatg ctggcatttc ctaggccatc cacttcaaaa gcgtaaatct
    15781 tttcgccctt gctgttggtg gtgtaagcgt agtttttgat tccttcttgg atttcatcct
    15841 gaagacgctt ggcatcagca ataacactct ggctatcagc taggtttaat gctgcgaaga
    15901 tttcttgcac ataacccaag actactacag caaacatatt tgacggaatc aagtaactat
    15961 actgacagca gtcatcgctc ggacgaaagg ctgaccaagt catacctgtc actgcaaagt
    16021 caggtccaaa gccatcattt accaaggtgt cttccttacg gtccgtgtct cggacaaaac
    16081 gataaggaga gttcttgtgg tcttgttcca ccgtccacag atggagaatt tccttagtcg
    16141 ctgcgacaaa aatctcatca aactgactag tctcgccagt ctctttccag aggagataag
    16201 ccaactgcaa aggatagcaa agcgaatcca cctcatactt gcgctcccag atccagccgt
    16261 taaggtctgt gtggtcagtc tcgtggtgcc ctttccagtt ctcctcaatg ttgaaggagt
    16321 tagcataggg atccttgagt accaaggtca tctgacgttt gaccaaacct gcaatggtct
    16381 gacgcaggag ggcatctctt ttagctacat gaaggtaggg tctgagttgg gctgtcgaat
    16441 ctcgaagcca catggcagga atatccccag tcaagacaaa agttgaacca tcttctaaga
    16501 tttcaaccgt attgtccaag gtatcggtgt agcaacgctc gaaaacatcc acccactctg
    16561 gatggtcctt agcccgctct gctacttcat ctatccattc tctaacaatt tctttcgaat
    16621 aaatcatcgt gcaattccct ctttcaaaca agtttcatgt tcagtatata gcttttgaga
    16681 cagaaaatac atacacaaat gatagtcatt tttctacaaa atagttattt ttgaaactcc
    16741 ttttctaaag gccctctttt tctgatataa tgtagaaaaa cagctaaagg aaagactatg
    16801 aaaccactac ttgaaaccat cgatacccgc tttggtactg ctagcaagca tgccttctct
    16861 cggggaaata ccctgccata cacaggcgtg ccttttggga tgaattactt tgtgccccag
    16921 accagtgacc agggtggatc ttggtttttt gatccgcatc tgcctatctt tcaggggatt
    16981 cgattaactc accagcccag tccttggatt ggggactact cttggctcct tctgacacct
    17041 gtcaccagtc aactgggggg agacagcctc tttcaccgcc agtcttctta tgatatagat
    17101 aaagcttgct tccagcctca ctatttgaag ctcttttctc tgcgttatca gattgaaacc
    17161 cagctcacac cgacttgcta tggtgcttct attcgtttga atcaaaagca aggcaaagcc
    17221 ctctccctct atcttcacgc agcagatgaa ctgacagtag agcaagtaga taagcggact
    17281 cttgccctgc gacaagaagg taaaactgaa actaacaaaa attcgctaac gatgttcact
    17341 gccctgcaaa tgaacacgga tattcttgct atcagccaag aagctggaga ctggcgaatt
    17401 gacttagcaa gtagtcaaac cgagatgcaa ctagccactt ctttcatctc tccttctcaa
    17461 gctctaatca atctacctca agaagatttt gatagctgta aaacaagtgc ccaagcggat
    17521 tgggaaaatc tcctccatcg ttttgacatt atagagacag gagaggctga ccgaaccttc
    17581 tttgaccact gtctctacag actcttcctc ttcccacaga ctttttatga ggttgatgag
    17641 tcagggaaag ccatccacat ggatctggct actggtactg tcaagcctgg tgtcctcttt
    17701 agcaacaatg gtttctggga taccttccgc accaccttcc ccctctttgc ccttatcata
    17761 ccggagcact atcaacgctt tttagaaggt ttcctcaata gctaccgcga tactggtttc
    17821 cttccaaaat ggctggctcc agatgaacgg ggtatgatgc caggtacact gctagatggc
    17881 attatcgcag atagcgcctg taaggacatg gcccccgacc tagaaggaga actcttccaa
    17941 gccatgctcg aaacagccag caaagccgac catctcggca tcaatggccg ccacggacta
    18001 gcccaatacc aagaactagg ttacctctct accgaccacc atgaaagtgt tagccatact
    18061 ctagactatg cctatagtga cttttgtatc gccagctgtg ccaaaaaact agagaacata
    18121 gaaatcgctg aaacctacaa ggctgcttca caaaattacc gccagctatt tgacgctgag
    18181 acaggttaca tgcgagcacg agacaatcaa ggaaactttc accctgactt ctctccttat
    18241 agttgggggc gagactacgc tgaatgctct gccattcaag ctactttagg cgttctccac
    18301 gacatccctg gcttaatcca actgatgggt ggaaaagaaa cctttagcaa ctatcttttg
    18361 aaagcctgtc aagatgctcc cctctttgaa acaacaggct atggttatga aattcacgaa
    18421 atgagcgaga tggctactgc tccttttgga caaatagcca tttccaacca gcctagtttc
    18481 cacatccctt atctcttccg ctacagcgat taccctgact acactgccct tcttatcaag
    18541 acgctccgtc agaaagcttt tcacccaagt tgggaagcct atcctggaga tgaagacaat
    18601 ggtagtctct ctgcttggta catctggtca gctctcggat tttatccaac ctgtccagga
    18661 aaaccaagct atgacctcgg aatccctctc tttgaccatc tacgagtcta cctagctaaa
    18721 gaagataaat ggctggatat ccatactaaa caaaaccaca accattttaa ctttgtcaaa
    18781 gaatgccgac tgaacaaaac actcgtatca actattcaac accaagacct cttaaaagct
    18841 gaacaactaa ctttcaccct cagctggcta ccaagtcact aataaccaaa agaacctttg
    18901 catcgcgcaa aggttcttct tttatgaaac ttggacttga agttgatcca caagctgacc
    18961 atccaccgtt aggttcagat agaaatccaa ggttttatct cctgcgaaat acagggttgg
    19021 tagatgcaaa tcttttttgc tttcccctgc ttggaattga aggacataaa tctcgtcctg
    19081 ataggcgaca ccatggacac ctgtccccgg ttgaatcgaa atcttagctt ctaaaggacc
    19141 actacattct ctgcgcttaa ctgtaaaata ggcattttct ccctttgcca cagctaggct
    19201 tttttctgca aatgctagtt cctgaacaac ttcttttttt gataatccag gagttttata
    19261 aagggaaatc ttggtcaata caggaataga ttgtgcctcg gtaatcatca cgcgcacctt
    19321 ttgtgcctct actagcgaac ctcgcaagag gcgcttatga ccaactgtga agcccctgcc
    19381 aaattcctgc cagacaccat ccacctctac ttgcacatgg aaagcagaaa tacgttggcc
    19441 taacttcaaa tcttctctca actcaattac atcaaaagtt ttaggagaac ctaagtcgag
    19501 ttctaactgg atgggcaagt ctgcatcgtt tgcccaagag ctggtctcaa ggccgtctgt
    19561 caaatggcga caagcaaagt ctgcggaaag agctggacca gatacctcag ctcccagagc
    19621 caaatcttct ttatagagct cattgcgata ggtcgcaaat tcataaagtc gttcaatatc
    19681 ctttgcatca aagagcccag cttgattcgg cggaatatta agcaagagtg gagttcctcg
    19741 ccctactgag tgaaagtaga tttcgaccaa ctcctcgaga gacttaggat cctgatcctc
    19801 atggtagaac cagcctggac ggatggaaac atctgcctct ccgattgaaa aaatcgtgcc
    19861 cgagggatcc ccgtgctgaa gatagttcag ctctgcttct gttcctagtt tatcaggatt
    19921 caccttttgc cacagtggat cacctgcata ccctcgttca ttgccaatcc agcggatact
    19981 ggtgccttct gttgaaaaaa tcaagcaatc gccctgcagg tcacgaatgg tttcaaacca
    20041 tttttcaaat tcataattaa ccttttgcgc gccctctcct ctggcaccat ccatccaaac
    20101 ctcagcgaac ttaccagcat tcccatagtt aggatttgat aagatttcct tcaactgagc
    20161 cagataatag gcattgtagt ccgcttctcg gtccacatga tagaggggac tatgggcatc
    20221 ccacggtgac aggtagaccc ccatatccat atcaaactct gtggcagctt gggatacttc
    20281 aaggagcaag tcgccctttc ctctcctcca aggactgacc ttaaccgaat aatctgtgtg
    20341 agctgtcgga taaaggacaa agccatcgtg gtgcttgacc accaaaatca actttttgaa
    20401 gcccgtttcc ttgagcacac gaacccactc acgcgcatcc aactgactcg ggttaaagcg
    20461 ctcaggatcc tcctgtccag tcccccattc ttggtcataa aaggtattag gaccgaagtg
    20521 gataaaagct gctagttcat ctcccagata agctagctga gtctgacttg gtaacggtcc
    20581 atgcggtttg attttcttca tcgttatata tctccttctt tagcaacttc tcttgttcac
    20641 aaggttatcc acaggttgtg gataataaac catgatctaa cagccagctc tttccaactc
    20701 caactggtag gctcaggatt ttgctcctca atattccctc ttcaaacagc tctgtcatat
    20761 ggttctgcta acacctctca gaatgctact ctccataatt attctcaggc ttctttcagg
    20821 tcattgtgtg aagaccattc actctccaga cttttccaca gattgtgaat aagtgattat
    20881 tctaaactat cacctcgtcg actataacaa aaaataaaaa gagggtcaat aagataatta
    20941 tctcttccta aatactcaga aaagattcta taatttgtac aattgaacaa gaaatgcttc
    21001 tccaaaatct atcttcaaaa gaatgttgca tctttttatc ctttcacaca aacatttctc
    21061 tttatacaga tccaagtgat aaccagatga taattggaca ctttttggtt atttgtgtat
    21121 tttttgaaaa attttttaaa aaaattttat atcctcttta atagaagttt atgaatttgt
    21181 atatatgtat tccatcctat gttatgtata ataacataaa attgtgctaa atatcataat
    21241 ttatattatt ttccgagaaa ttatagccat tgacattacc taggaattgc gttataacat
    21301 acatgtaagc ggtacccaaa atggtgccaa gtcaaaattt ttaaggagga aaatacatgt
    21361 cttcacatcc aattcaggtc ttctcagaaa ttgggaaact gaaaaaagtt atgttgcacc
    21421 gtccaggcaa ggagttagaa aacttgttgc cggactatct tgaaaggctt ctttttgatg
    21481 atattccttt cttggaagat gctcaaaaag aacatgatgc atttgcccaa gctcttcgcg
    21541 atgaaggaat tgaggttctc tacctagaac aactcgctgc tgaatcattg acctctccag
    21601 aaatccgcga tcaatttatc gaggaatact tagacgaagc caacatccgt gatcgtcaaa
    21661 ctaaggttgc tattcgtgaa ttgcttcacg gcatcaagga caaccaagaa ttggttgaaa
    21721 aaacaatggc tgggattcaa aaagttgaat tgccagaaat tcctgacgaa gctaaagatc
    21781 taactgactt agttgaatca gagtatccat ttgcaattga cccgatgcca aacctctatt
    21841 tcactcgcga cccatttgca acaattggaa acgccgtatc gcttaaccac atgtttgcag
    21901 acactcgtaa ccgtgaaaca ctctacggta agtatatctt caaataccac ccaatctatg
    21961 gcggaaaagt ggatttggtc tacaaccgtg aagaagatac gcgtatcgaa ggtggagacg
    22021 agctagttct ttctaaagac gtccttgcag taggtatctc tcaacgtaca gacgcagctt
    22081 ctatcgaaaa acttttggtc aacatcttca agaaaaatgt tggcttcaag aaagttttgg
    22141 cctttgaatt tgctaacaac cgtaaattca tgcacttgga tactgtcttc actatggtag
    22201 actatgacaa gttcactatt cacccagaaa tcgaaggcga ccttcacgtt tactcagtta
    22261 cttacgaaaa cgaaaaactt aaaattgttg aagagaaagg tgacttagct gaacttcttg
    22321 ctcaaaacct tggtgtagaa aaagttcatt tgattcgttg cggtggtggc aatatcgtag
    22381 cagctgcgcg tgaacaatgg aacgacggtt ctaacacttt gaccatcgca cctggtgtgg
    22441 tagttgttta tgaccgcaat accgtgacca ataagatttt ggaagaatac gggcttcgct
    22501 tgattaagat tcgcggaagt gaattggttc ggggccgtgg tggacctcgt tgtatgtcta
    22561 tgccatttga acgtgaagaa gtgtaatcgc tgttcggtat tcgtcaatag aaaatgtaaa
    22621 aaatagaaag aggaaataat aaaatgacaa attcagtatt ccaaggacgc agcttcttag
    22681 cagaaaaaga ctttacccgt gcagagttag aataccttat tggtctttca gctcacttga
    22741 aagatttgaa aaaacgcaat attcaacacc actaccttgc tggcaagaat atcgctctcc
    22801 tatttgaaaa aacatctact cgtactcgtg cagcctttac aactgcggct atcgaccttg
    22861 gtgctcaccc agaatacctc ggagcaaatg atattcagtt gggtaaaaaa gaatctactg
    22921 aagatactgc taaagtattg ggacgtatgt ttgacgggat tgaattccgc ggattcagcc
    22981 aacgtatggt tgaagaattg gcagaattct caggcgttcc agtatggaac ggtctaactg
    23041 acgaatggca cccaactcaa atgctcgctg actacttgac tgttcaagaa aacttcggtc
    23101 gcttggaagg cttgacattg gtatactgtg gtgatggacg taacaacgtt gccaacagct
    23161 tgctcgtaac aggtgctatc cttggtgtca atgttcacat cttctcacca aaagaactct
    23221 tcccagaaaa agaaatcgtt gaattggcag aaggatttgc taaagaaagt ggcgcacatg
    23281 ttctcatcac tgaagatgct gatgaagcag ttaaagatgc agacgttctt tacacagacg
    23341 tttgggtatc aatgggtgaa gaagacaaat tcgcagaacg tgtagctctt cttaaacctt
    23401 accaagtcaa tatggactta gttaaaaaag caggcaatga aaacttgatc ttcctacact
    23461 gcttgccagc attccacgat actcacactg tttatggtaa agacgttgct gaaaaatttg
    23521 gtgtagaaga aatggaagta acagacgaag tcttccgcag caagtacgct cgccacttcg
    23581 atcaagcaga aaaccgtatg cacactatca aagctgttat ggctgctaca cttggtaacc
    23641 tttatattcc taaagtataa ttttagataa taaaccgtct accaacagct atgagggctg
    23701 cgactaatag ctttagtccg gtcctctttt atataatggt aatctattat ttcttataaa
    23761 atatgtgaaa aatcattaaa ttgaaatcta aacgcattct attgagtgtg ataaaggaga
    23821 atttatggca aatcgtaaaa ttgtagtagc tttgggagga aatgcgattc tttcttctga
    23881 cccatcagca aaggctcaac aagaagcttt agttgaaaca gctaagcatc ttgtaaaatt
    23941 gattaaaaat ggagatgatt tgattatcac tcacggtaat ggacctcaag ttgggaatct
    24001 cttgctccaa catttggcat cagactctga aaagaaccct gccttcccac tcgactcact
    24061 tgtcgctatg acagaaggta gcatcggttt ctggttgaaa aatgctttgc aaaatgctct
    24121 cttggatgaa ggcatcgaaa aaaatgttgc ctctgttgta acgcaagttg tcgtagataa
    24181 aaatgatcca gcttttgtta acttgagtaa accaatcggt cctttctatt cagaagaaga
    24241 agcaaaagca gaagccgaaa agagcggagc gactttcaag gaagatgctg gccgtggctg
    24301 gcgtaaggtc gttgcctcac caaaacctgt tgacatcaaa gaaattgaaa ccatccgtac
    24361 tcttttaaat agtggtcaag tcgtcgtagc tgcaggtggt ggcggtattc ccgtcgtcaa
    24421 agaaaacaat ggacatttga ctggtgtcga agcggttatt gataaagact tcgcttccca
    24481 acgtttggca gaattggttg atgcagacct cttcatcgtt ttgacaggtg tagattatgt
    24541 atttgttaac tacaacaagc caaaccagga aaaattggaa catgtgaatg ttgcccagct
    24601 ggaagaatat atcaaacaag atcagtttgc accaggtagc atgcttccaa aagtagaagc
    24661 agctatcgct tttgtcaatg gtcgtccaga aggaaaagca gttattactt cccttgaaaa
    24721 tctaggcgcc ttgattgaat ctgaaagtgg aacaattatt gaaaaaggat aagttgtttt
    24781 actaataaga tgtattctat ttctagtatc tttatatcaa attagaaatt attcttgaaa
    24841 acatgtacaa tatttcaaaa gatattagtt ttttagactt taatatggta aaacaaatat
    24901 aaatagaaag cgttttctta aatgtttatt taagaaagta gttggttttt tacactttgt
    24961 tagacatcag gaggaaaaac aaatgagtga aaaagctaaa aaagggttta agatgccttc
    25021 atcttacacc gtattattga taatcattgc tattatggca gtactaactt ggtttatccc
    25081 tgcgggggcc tttatagaag gtatttacga gactcagcct caaaatccac aagggatttg
    25141 ggatgtcctc atggcaccga ttcgggctat gctaggtact catccagagg aaggttcgct
    25201 cattaaagaa acgagcgcag cgattgatgt agccttcttc atccttatgg ttggtggttt
    25261 ccttggcatt gtcaacaaaa ctggtgctct tgacgtaggg attgcctcta tcgtgaagaa
    25321 gtataagggc cgcgaaaaaa tgttaatttt ggtactaatg cctttgtttg ccctcggtgg
    25381 tacaacttat ggtatgggtg aagaaacaat ggccttctat ccactccttg tgccagttat
    25441 gatggccgtt ggttttgata gcctgactgg tgttgcaatt attttgctcg gttctcaaat
    25501 cggctgtttg gcatctactc tgaatccatt tgcgacaggt attgcttcag cgactgcggg
    25561 agttggtaca ggggacggta tcgtacttcg tctgatcttc tgggttacct tgactgctct
    25621 tagtacttgg tttgtttacc gttatgcgga taagattcaa aaagatccga ctaagtcact
    25681 ggtttatagt actcgcaaag aagatttgaa acactttaac gtagaagaat cttcatctgt
    25741 agaatctaca cttagcagca aacaaaaatc agttctcttc ttatttgtgt tgacattcat
    25801 cttgatggta ttgagcttca ttccatggac agaccttggc gttaccattt ttgatgactt
    25861 taatgcttgg ttgactggtc ttccagttat tggtaatatt gtcggttcat ctacttctgc
    25921 actaggtact tggtacttcc cagaaggcgc catgctcttt gcctttatgg gtatcctgat
    25981 tggtgttatt tatggtctta aagaagataa gattatctct tccttcatga atggtgctgc
    26041 tgacttgctc agtgttgcct tgatcgtagc gattgctcgt ggtattcaag ttatcatgaa
    26101 cgacggtatg attaccgata caatcctcaa ctggggtaaa gaaggcttga gcggtctatc
    26161 ttcacaagtc tttatcgttg taacttatat cttctatcta cctatgtcat tcttgatccc
    26221 atcttcatct ggtcttgcca gcgcaactat gggtatcatg gctccacttg gagaatttgt
    26281 aaatgtccgt cctagcttga ttatcactgc ttaccaatct gcttcaggtg tcttgaactt
    26341 gattgcacca acatctggta ttgtgatggg agctcttgca cttggacgta tcaacattgg
    26401 tacttggtgg aaattcatgg gcaaactcgt agtcgctatt attgtagtga ccatcgccct
    26461 tcttctcctt ggaaccttcc ttccattcct ataaaatagt gagtgaggtg attccatgaa
    26521 aatagatata acaaatcaag ttaaagatga atttcttata tcattaaaaa ccttgatttc
    26581 ctatccttca gtactcaatg aaggagaaaa tggaacacct tttggacaag caatccaaga
    26641 tgtcctagaa aaaactttag agatttgtcg agacataggt ttcactacct atcttgaccc
    26701 taaaggttat tacggatatg cagaaatcgg tcagggagca gagcttctgg ccattctctg
    26761 tcatttggat gttgttccat caggtgatga agcagattgg cagacaccgc catttgaagc
    26821 aactatcaaa gacggctggg tattcggacg tggtgtccaa gatgataaag gcccttcgct
    26881 cgcagctctc tatgcagtaa aaagcttgct ggaccaaggt attcagttca aaaagcgcgt
    26941 acgctttatc tttggtaccg atgaggaaac cctctggcgc tgcatggcac gctacaatac
    27001 catcgaagaa caggccaaca tgggctttgc acctgactca tcttttcctc tgacctatgc
    27061 tgaaaaaggg cttctacagg tcaaacttca tggccctgga tcggatcaac tagagcttga
    27121 agtaggaggc gcctttaacg ttgtaccaga caaggccaac taccaaggtc ccctctatga
    27181 acaggtttgt aacggtctca aagaaactgg ttatgattac caatccactg aacaaaccgt
    27241 aacggttctc ggagtgccaa agcatgctaa ggatgctagt caaggtatca atgctgtcat
    27301 ccgactagct accattcttg ctcctctcca agaacaccct gctctcagtt ttcttgcaac
    27361 acaagcaggt caagacggca caggaagaca aatctttggt gatatagcag atgaaccttc
    27421 tggtcaccta tcctttaatg tcgcaggtct catgatcaat catgaacgtt ctgaaatctg
    27481 tattgacatt cggactcctg tcttagctga taaggaagaa ctagtagagt tgcttacaag
    27541 atgtgcacaa aactaccaac tccgctacga agagtttgac tatctagcgc ctctatacgt
    27601 cgcaaaagac agtaaactcg ttagcacact gatgcaaatc taccaagaaa agactggcga
    27661 taacagtcct gctatttcat ccggtggtgc cacttttgct cgcaccatgc caaattgtgt
    27721 agccttcggc gccttattcc caggagcgaa gcagacagaa catcaggcaa atgaatgtgc
    27781 cgttctagaa gatttgtacc gtgctatgga tatttatgcc gaagccgtct atcgacttgc
    27841 aacttaatca ggcaactgtt tctaccaaaa aaaatcgacc gattaatgaa ctgcacccca
    27901 aaagttagac agaataaatc taacttttgg ggtgttttat tatgaaattg agttatgaag
    27961 ataaagttca gatctatgaa ctaagaaagc aaggacaaag cttcaaacag ctttcaaaaa
    28021 gatttgtgtg gatgtttctg gtctaaagtc atctgaatct ttgagatgag ctttataaat
    28081 cgcttttttc agtttttgca ctggtgtttc gataaactca aactttttag ccgtggtatt
    28141 gcctgatttt atagtatatt gaaactagaa tagtacacct ctacttctaa aacattttta
    28201 gaaatcgatt tgactgtcct gatcgatttg tcctgttctt atttcatttt actatatttg
    28261 agccacttcg tctttaacgg ctttattcat aagctcttgt aatttttctt tactatcaat
    28321 tacttctgat tttccgttgt aatttattgt aataggtttt aacttaccta atttctcgac
    28381 acgctcagaa atttgatctt ttttgaaggc tgcatatgtt tttcctaaga ttttttcgaa
    28441 aatatattta tcagatagcg gtttgccttc ttcttcagct tggtttttgt attgatttga
    28501 aacataagga acaaatcctt catagtaacc taatgctccc ataagttcaa aagcttgttt
    28561 tctaattcaa accattgcaa ctcagatttc agcttttcag ataaatcctg ctcatccaaa
    28621 taatgacttg aaattagtgc tgaactcgtt tctgtatcct gtacaggctg agcacccata
    28681 ccagcaaaaa aataaactcg ttcctagcaa gaccgaacaa gctcctattg catatttcct
    28741 caaagaaaaa cgctgctttc tctcaaattg aaattctttc atcccatctc ccatcattca
    28801 ttattactgt atattttgta tatcagaaat agtttgtatt cacaaatctt tctagttatt
    28861 cccttatcat tcctaattaa gggagataac atacaataat ttttagttaa atgtatatcg
    28921 atgttttttg tttttcttaa taaacgcaat acaaaaagag cctgttgcca agctctttat
    28981 actcaatgaa aatcaaagag caaactagga aactagccac aggttgctca aaacaccgtt
    29041 ttgaggtagt agataagact gacgaagtca gctcaaaaca ctgttttgag gttgcagata
    29101 gaactgacga agtcagtaac atctatacgg caagacgacg ctgacgtagt ttgaagagat
    29161 tttcgaagag tattagtcta ttatttcttc tcagcgcgaa gggctgacaa gatttgtgta
    29221 cggatatcat ccacaccatt tggagtattt ggtaaaaaga tggtttgatt tcctttagag
    29281 gcaaaggtat tcaaggtatc caaatactgg ttggtcaaga ggatagacat gatttgttct
    29341 tctgtcatgc caacattggc ttccttgagt tcggtgatag actctgccaa tccatccaca
    29401 atcgccttac gttgttgggc aatccccaca ccatgaaggc ggtctttttc tgcttcggct
    29461 tcagctgcag tgacaatttt aatcttgtca gcttccgcca attcttgtgc tgcgacccgc
    29521 ttacgttgcg ccgcattgat ttcattcata gattgcttaa cttctgcatc tggttcgacc
    29581 ttggtaatca aggttttcac gataatgtag ccgtaagtgg tcatttcttc tgctacttgg
    29641 tgttgaacct caagggcaat ctcatctttt ttctcaaaca attcatccaa ggttaatttt
    29701 ggaacagaag agcgaagagc atcttcgata taagatttaa tctgagattc tggacgtatg
    29761 agtttatagt aagcatctgt cacgctctgc tcgttgacac ggtactgagt cgctacattc
    29821 atcataacga acacattgtc cttggtctta gtctcaacca caatatcact ttgcaacaag
    29881 cgcaactgaa tccgtgctgc aatcgagtca atcccaaaag gcaagcgaat atgaataccg
    29941 ctattagcaa ccttttggta tttcccaaag cgttcaataa tcgccaccga ctgctgacga
    30001 accacataaa ctgtactcag tgtgactatc accaatagga gcacacaaac aatcagaaaa
    30061 atcatgaaaa atattgccat aatggaacct ccacaagtat ttttctagta ttatagcaca
    30121 tttaaagaag gctgtgccgt ttttactgcg atttttcctg aaatgtcaat aattagaggt
    30181 gaattgtcct attgtcgtct aatctcttgc taaaataact ctttataaaa ggcaatcgtt
    30241 tcttctaagg ttggcataaa tggatttcct ggtgcgcagg catcaatcaa ggcattctta
    30301 gaaaggtatt caaagtcgaa atctttttct tcaataccaa gttcagtcaa tttcttagga
    30361 atacctactg tctcagaaag cttctcaatc tcagcaatcg cataatcggc acactcttga
    30421 tctgatttac cttccacatg aaggcccaag gctttggcaa cattgcggaa agcttctggt
    30481 acacgtttag cattttcacg ttctataact ggtagcaaca tggcacagca aacaccatgt
    30541 ggcaaattat atactgcacc gagttggtga gccattgagt gaacataacc aagaccagca
    30601 ttattaaagc tcataccacc aaggaagatg gcattgacca taccttcacg cgcttcaata
    30661 tcatgtccat tttctacagc acgaggaaga tattccttga taagctcaat agcaccaata
    30721 gacagtttct tggttacatc ataagcacca ggtgttacca aagcttcaac agcgtgagtc
    30781 agagcatcca taccagtagc agcagtcaga cctttaggtt tggaaagcat gagttccggg
    30841 tcattaacag agataagagc aaggctattc ttgtcaacca ttaccatctt aaccttgcgt
    30901 tcttcatcag taatcacata gttaatagtg atttctgcag aagttcctgc cgttgtattg
    30961 atagccacaa ctggcaagcc ttttttagca gacttatgaa gcccttcata atcctgtggt
    31021 tttccaccat ttgtagccat gatagaaata caactagctg catcctgtgg agaacccccg
    31081 ccaagactga tgataaaatc acatccatgt tcttgcaaag cagctacccc atctgtgaca
    31141 ttcttacaag tagggtttgg ctctacatcg ctaaagatga catattcgat tccttctgta
    31201 tccagtggtt ttaaagtctt aggtaaaata tcactgcctt cgatgtactt atctgtcacc
    31261 aaaagtgcct ttttatagcc aagttccttg atataaggac ccacttcatt tacaacacct
    31321 tttccaataa ggttgactgc cggaacataa aatgtagcca tataattttc ctcctgcgcc
    31381 tccgcgctat ctatttaaca tcattatatt actttttgta ttcgttttca attatttgtg
    31441 aattgtttaa caaatctttt taaaaggata ggagggacgt aagttcacct cctatataaa
    31501 caagttttat ttatgtagtg gtcccaacaa ctgacatgca cgatagtctg ctgattctag
    31561 atcttctgtt ccaaataagg accaattttt aggtctaaag atatcttcct caggtacatt
    31621 atgcatattg acaggaattc tcaacataga agccaaggta atcaagtctg ctccaatgtg
    31681 tccatatgtt atggctccgt gattagctcc ccaattattc atgacgtcat agacagactt
    31741 gaaagcacct tttcctgtca aacgtggagc aaaccaagta gttggccatc ctggatctgt
    31801 acgattatct aaagtatggt gaacatcttc aggaagttca agtgtataac cttctgcaat
    31861 ttgtagcact ggaccaaccc cttttagaag attgagacgt accattgtta ctggcatatc
    31921 ccccttcgtc aagaaacgag ttgagaatcc tcctccacgg aagtattcgc ggtttgctgg
    31981 tgggaagtct gtattttcaa gcatagcctg cacttcactt tcatccaact cccagaatgg
    32041 tttcataaca ggtttgccat ctcgagtagc ttgacctgta ccatctaatg tacaagaacc
    32101 agagttgatt agatgtaaga agccagctgc agcacgaccc tctaaagtat atcctgttac
    32161 acgttcaaca gcctctggac tccaataagt acgcacatca gcaaagattt gtggagtatt
    32221 tgttaataga taattaaaga gcatagacac accatttagt gaatcattct ctgtcgcaaa
    32281 tacaaatggt tttcgaatac cattccagtc aaactgagta ttgaggaaag tttccataaa
    32341 atctccattt ggaaaatggt ctgtccactg acgttgacct tggaaaccag ctactaaagc
    32401 atggtgacca actgcttctt cctcaaaacc aagttcagca agtcttgggt taccaaccat
    32461 taagtcacgt ccaatcatga acatcttaat aacaaattcc cattgtctat ctttttcttc
    32521 acggcttaaa acaaggtctt cacggttatg gtcgaatcct tcttttacgt tttctttcac
    32581 ccatttgagc gcacgttcga actcttcagg gtcgtaaata ccacggtcca tacggcgtgt
    32641 gaactccgtc atatctaccg attcatttcg cattcctaag tattcttgga agaaatccgg
    32701 atttacaata gaaccaccaa tccccatcga aacactaccc attgataggt aagcagtgtc
    32761 tctcatcaag ccagttgcaa gagctgcccg cgcataacgt aaaagttttt ctttgacatc
    32821 ttctggaata gctgtatcat tagcttcctg aacatctcta ccataaatcc caaaggctgg
    32881 aatccctttt tgagtatgtg aagctagtac agctgcaaga tagacagctc ctgggcgttc
    32941 tgtcccatta aatccccaaa tagcatgagg aatatctgga gacatatcca tagtttcact
    33001 accataacac cagcatggtg taactgtaat tgttgcgcaa acatttgatt ttttgaacaa
    33061 ctcatgggaa gctgcagcct ctggtacacg gccaatagta gatggagaaa tcacgcattc
    33121 cacaggttcc ccatctggat atttcaatgt gcttgaaatc aaatctgcca cacttttagc
    33181 catgttcatt gtttgtactt caagtgattc gcgtacacct tgacgacgac catcaatagt
    33241 cggacgaatc ccaatacgtg gatgttgaat catactattt tcctcttatt tttctgtttc
    33301 tttcatacta ccgatgataa tttttaaaat tacttataag tataaacctc tacctctgcc
    33361 aaacttaaag gaattcctgc gtttctcaaa gaaattctaa ccttttttcc cttcagccct
    33421 tttaagtcta tggatagatt attgctttct aaactgtcaa tatgttgttt aaaaacttca
    33481 tgattatttg aatcatatat aataatatca aaatttgata atctctgaat ttcagcatct
    33541 gttctattat aaataattaa cttttctaat tcttcggttt gtgctaaatc tatctcccac
    33601 catgaaggag aatctccttt ggtatgagtc actgaatgat gaccataatc tccgttttta
    33661 tttccatcaa ctgctagacg agaaaaacca ttgtaatccg ttgaactctg tcgagtttct
    33721 ttggttaatg caatattaga aagtttcttc ggagttctct ttgaaccata gacttcaact
    33781 tccgctaaac ttaacggaat agctgctgat tttaattcta ttttgactag cttagcccct
    33841 acagaaggta cttttaaaga taacaaacca tcaactactt tatcaaaatg tcttctaaaa
    33901 acttcttctc ctgatgaaga tagaaaaata acatcaaaat tagataaacg ctgaggttcg
    33961 gcatctgttc tattataaat atcaacttta gaaaccgtaa actcttctcc cagatcgacc
    34021 tgccaccaag cgttagaatc tgccttagta tgagtcaccg aatgatgtcc gtaatctcca
    34081 tctttattac catcaactgc taaagcagct acaccctcat aattggttga actttgagta
    34141 gctaccttat ttgtagagac tactttatct tctgttattt tatctatatc ctcttcagat
    34201 tgcttaccat ctgattctct aaaaacctct acttctgcta aactcaaagg cactccactc
    34261 gttagtaatt taactttaat ataccttgct cctttttctt tgaaatctag actaacagat
    34321 tcacccgaca aattattaac atgtttctta gcaacttcgt ttctattatt gtcatataga
    34381 atcacatcaa aattagatag acgttgagtc tcagcatctg tgcgattata aattttaaca
    34441 agcccaactt tatccatttt tttcaaatcg acttcccacc aagagggatt atctgcccta
    34501 gtgtgtgtta ccgaaccaga gttaaaatta ccatttctgt taccatccac agctctatta
    34561 gggtctccat tgtaatctac agaactttgt gttgttggtt ttgcatatgc tatattcaaa
    34621 ttaccatcat taaatttatc tggtgttggg aaagggactg ggcctgtccc ttcagtattt
    34681 atagacatct ctaccattcc attatgatta accgtaatgg tataaacatg ggtattctca
    34741 tcccaatttt ctgtataagt ataatgattt ttatcgccac ttatatttat ctgaggttta
    34801 tgaccagtat gcccttttaa tgtaagtgtt gttgtcctaa agtcattatc tacaggattg
    34861 atggaataat ttttgcttat ccagttcgct aactctaatt cttctttctt ccaacttttt
    34921 gatgcatcaa aatttcctga taatgcccac atagctgtct tatctgtcct gtaattgttc
    34981 aataaaatat gtaaattatt tggattttct ttaacaacag cgtaagtatg tggcgtcaaa
    35041 tctaacgata acgactttgt attattagta tacataggca acattacttg ctgattttta
    35101 ttgatattag cattactatt ataaatatac caggaattac ctacacgctg agcataccca
    35161 tctccttcat aaagttttgg ataaagcgag tttaaatagt tgactttact agacaattcc
    35221 tcactatttt tagtcaaaat ttttgcatta gggaatatag atgaaatctt ttccttatca
    35281 attttctcat gtattacagg aagaatatga tatctcccat tattatataa aggcattgtt
    35341 tcatcattcg aataaagtcc ttgataaaat ccgtttaatg aactaatcct accttctcca
    35401 ttccaaaata cagcttttgt tctatttaca acttcttcct tacttggagc tggattttgt
    35461 atagcatgtc taaagaaagg aataatacct ttagtaaatg ctggagttgg tacatcattt
    35521 gtcataaatg tatacgcggc acattcaaaa ttataaactg tgcctccccc agtatataca
    35581 ttcatcattt ccatagcaat cattgattct ggttccgatg cataggatct catatcccta
    35641 gctcttccag tttcaaatgt gtttgtataa tgtttttccc accatttcca tgtatctgtt
    35701 gatgagcccc agttatcaca taagccactc aaccaaaatc cactaacgat agaatctgta
    35761 cccgcatcat ctcttattgg cgtattttta gttgccaaca ccaaattttt atgatatttt
    35821 tgactcgctt caaagaatgt cggatcattc ataatagttt cccagaacca tttttcatga
    35881 tcatgccaga taaaatgcgc tccatatttg gcacaaactt ccaaatattt agcactatgc
    35941 ggagctaact ggttattgta aatccaataa ttctcaatat ttaaaacacc ttttaacaca
    36001 ctatactttt ggaattgttc atctaaccac tctggaggaa ctgtattacg ctctccagcc
    36061 gacataataa ccaagaaaac tggaatgttt agactttgag cttcctccaa catcttgaca
    36121 taccattctc tcaattcttt cgtatctcgt ggaatacaac ttgttggttt acagactttt
    36181 gcaggatgaa gttcaatcgc tgcatatggt tttacatctt caggaatagc ttcccatgct
    36241 cccttcaatg tgttccccca ccataatccg ttaccattat cattgccata caacggagaa
    36301 agcaacaatg gcgattcatt attaatcgtc gttctcattt gaacacgatt atcagcctta
    36361 actcctgcta acaatccaaa acataacatc ccaatacata caaacagtat tgtgattaat
    36421 tttcttttta ttttttcttt attcatgact tatacctaaa aatttaactc aataattttt
    36481 tctgaattaa ataccaattc aatattttgt acatcagtat ttttgccata tattcttact
    36541 cttacttttt gatctttgtt tcctccttcc aattttagga atgttatatc cccatttttc
    36601 caagcaaacg ataccttata tcctcctctt actctgaaac ctttcacttc tccttctgac
    36661 caagcagaag gtaaagctgg aattagtgat aaccaattat gatggctctg tactaataat
    36721 tcacaaattc cactcaccaa acctaaatta ccatcaattt gaaatggtgg atggtcaaga
    36781 aataaattgc caagagtcgc attatttaac aaaccattaa tctggttata agcaggttca
    36841 ccttgatata gtctcgcaaa aaaatgaatc agccatgcag cactccaacc tgtttgtgta
    36901 ctagcatgca aaccacttac taaccaatta ttaatcgctt gctccctctc ctgtgaagat
    36961 aaaaagttag cgtttgataa tctcctattg atagtgattt tagctgcttc tgctaattcc
    37021 ggagttttat gaatatcaat ctcattataa ggataaagcc caaatagagg tgaaatgtgt
    37081 ctatgcccag gctctacttc ttcataatct tctaaccatt cttggatttg cccattacta
    37141 cctatttttg ttttaggtag tttctttttt aactccttca cacgactaat aaaatccgaa
    37201 ttgtctccta attgttttgc aattccaatg catgaatcac aaaaatatct taaaatttga
    37261 ttatcaattg tagatgatag acaagcattt ccttcaatac cattttttaa gcgatattta
    37321 ttttccggtg agacacttgg acctgtcatc aagtagccat ccacctcaaa taaataatct
    37381 tcaaagaaaa gaaatgcttc ttttatcatt tcaaaatgtt ccgtaagaat acgctcatct
    37441 tggaaatata aatagtgttc ccaaatatga gtacataacc atggaatagt taatacccaa
    37501 attgcagccc ccatggcatg agattgggga gccgtatcgc caaaaccatc cgtattatga
    37561 tgtgctgtaa aacctctagc tccatacatt ttcttagcgg ttagtcttcc cggttctctc
    37621 attctttcga gcatatcaaa taatggatat tctacttctg gtaaatcaca tggacctacc
    37681 atccaataat tcatttgagt attaatatta atcgtatatt tagaacccca aattggattt
    37741 aattcatcac accatattcc ttgaagattg gcaggtaaac cattcggttg actagacgat
    37801 attaacagat atcttccata atgaaataac aagttagtca agtagttact atacttttta
    37861 gtgttttcaa gaagtagatt cgttggaatg ctaagacaac ctttactata gtctagttta
    37921 aaatcaactc tattaaattg ctcctgatat ttttttacat gttcatcttt ttctgtaaag
    37981 taatcaatac tactaaattc tccctgaaga gaagaaatat ctatatttcc ccaataatcc
    38041 gtcattgatt tgagataaag aaatacctct gtagcattcc gaataactat tgtctctccc
    38101 aatacactta cttcaccatc cgtaacctta gaatgacata ctactttaaa ctgaacacct
    38161 tttctacctc cagcagaggc cgacattaaa attgtacttg aatccagttt agatacttcg
    38221 tcattaaacc gtttatttct acccaaatta atgtttaaat ttaatgtgtt ttgaactgat
    38281 gacactatac ggcaacataa aatattctta ttaaaactcg taaaatattc tctttttatt
    38341 tgtaaattac aactattagg ctcaaacaca acattagaaa tagctgtatc taaatctagc
    38401 tctctttcat acaatgaaag agcacaagac tgaatatcta tatgctcaat gtaaagttcc
    38461 ccaagtaatt catagtggct ttgatctctt ggggtagcaa acattgttaa ctttatcaat
    38521 tcttcggctt tctgaatttc tccatctaaa agatattccc gaattttttt aagatgcaat
    38581 agtgagtctg gattatttct atctgacttt cctctatacc aaatagtctc atcgtttagt
    38641 tgaatacatt cttttgtagc tgaaccataa atcataccac ctaaatgacc gttcccaatc
    38701 ggcaaggctt cattccaatt tgcggcagct ttcttatacc ataatttcac tctttacctc
    38761 tcttccaaaa tggaggtgat atcccaaata ccacctccac actttctact acttcaaaat
    38821 tcctaaaaca actaggataa ctccaatagc cataacacta aagattagta caaccggatt
    38881 ctttcctttt ctaattaatt tacacattaa taaagtcaaa gccataggga taaatcctgg
    38941 aattaatttt gtaatcattt cttgaacaga aataacaagt tccccctgct taaattctaa
    39001 tccaaaatta ataccaacca ttgatggaat caaaccaccc actagtacta gccctaatgc
    39061 tgtcgccata ctcgtaacgc gattcaatgt tccttttgta ttattttctt ggataagact
    39121 agaaccctta gtatacccat atttcaaacc gaaatattta acaggaatat taataatatt
    39181 aaacaatatt aaggcgataa agatacctaa agcaccgccg tctttagaat aagacgcacc
    39241 aatactaaaa cagataggaa ctagtgtcag ccagaacaaa ctatctccta gaccagccag
    39301 tggccccatc aagccaactt taataccagt aattgaagct gcaccttcat ttccttcttg
    39361 ttcttccata gcggaagtaa ctccaagaat aaatggtgcc gctgtttgat gagtattgaa
    39421 aaactcaagg tgacgtttca ttgcaggaga agctgaatct ttgtctgggt atagtttttt
    39481 caatactgga agaattgtat atagaaaacc taggttctgc attctctcat agttccatga
    39541 agaaccatac ataaaacttc gtttgaaaac ttttttaagt tcaactttag ttactttatt
    39601 attcatcata gatcaagatc ctcctcaaca tcactacttg aagttgtttc ttgtggttta
    39661 cttccaatca tatcgtagaa gtatgctacc gcaataccaa ctagtgagat cccaatggtt
    39721 gacattcctc catacacaga acaaatgaat ccaatcaaca agaataccca catatttttc
    39781 ttgagcatca tatttaaaag cataccaaaa ccaattgaag gtagtaaagc acctgcagag
    39841 ttaagtccct gcataacgat tggtggaacc ttagcaaaca agtctgccac atattcccct
    39901 ccaagcataa tagctaggaa aattggtaca attttaaata acgtgattaa aaccaaactt
    39961 gaataatgat aaaaaccgat ctttgaataa tctccgtttt tagcatcatt atcagctttt
    40021 ttcacaaaat aaacatctaa agtttttgca agaacatcca actgttgggt agcaactgca
    40081 attggaactg ctatagcgat accagcagtt tctccttgac cagataaaat accaaatgca
    40141 gtaccaataa tcgcacctga aatagtatct ggtggagtgt aacctccaat acctgttaca
    40201 ccgagccaag ttaattcaag agctgaacca ataagaacac cttgggtgaa atctcctaag
    40261 actaagccaa ccattgcact tgtaactaag ggacggtgaa tcataaataa cggtccatta
    40321 tagtcaatag tggcaataat cccaactaat gtcaccagta atgcttgtgt gaatagcata
    40381 tactgtacct ccttaaatta tttttataaa aatttttcca acattgtaac tttatcatta
    40441 ggaaccattt gaatttcaac tctcgttccc ttatcaacta ttttcttaaa ataatatttg
    40501 tcttcttcac ctagagctac acctcccgtt accttttcat tttcctccgt tttactcatc
    40561 tgtcctacat tgaggtactc caattttaaa tttccttcaa tagaatcata cacatctttt
    40621 ggatttgtat atatcagcat tgttctcttt tttattggca cagagtttaa aacttccaca
    40681 aaccgtttta cactaaagaa aacaattttt aaacctaccg gtgcagaaat ctttaaaata
    40741 gattgtcgtg ttttatcttc tgagatgcga tcattaacaa tgataacttg ctcaatatca
    40801 tactttttta gccacgtagt gacaacttga ccatgtacca gacggtcatc aatacgaaca
    40861 aactctatag acataaatcc tcttcctcct ctacgttaag ttgttgttta acattaaaca
    40921 aactattttg agcattttga acaatttctt ctaaattgat ttttgaatca taacttgata
    40981 ttaattccac taggagaggg atattaaacc ctgttacaat atcaactgaa tccaaattta
    41041 aaaaccgtga caaagccaca ttattaggac ttcctccaat caagtcagtc aaaacgataa
    41101 cctcttgatt tgagtctaac agttcattta cttgattttt aaaataatgt tcaaactcta
    41161 caatattctc tccaggcatc aaacctaatg tcctaactct atcatttgtt gtctcaccaa
    41221 caaacatttc tgcggtcatg agagctccgc tagcaaaatt accatgactg gcaactaaaa
    41281 ttcctctatt aaacattttc tctttcaaca actactcctt tcttaaggat aatattagca
    41341 taaagtgaag tttctcctgt agcaacaata gcataagctt tcttactacg ttcataaaag
    41401 tcttctcttc taagataagt aatcgtttta agatctgtac catgaccttc aatcatctgt
    41461 ctataggtac cccatatctt aggaatatca tcacccgaaa caacgttcat aaactgaatt
    41521 gaactatcga cgtaactatc taatggcatt aaatacagaa tggaatctaa taattctgga
    41581 atatttacac catcacaacg aattagctta tttgcacatg aggcagaagg ataattcgcg
    41641 tcagctaata ctatttcatc tccatgtccc atttccatta aagtcttcaa taaatctgga
    41701 gaaatatttt tcggtatatg ttttaacatt aatatcctcc ctattttctc tgaccgtatg
    41761 ttttaaattt ttctgccatc aattccatct cctcatcagg aagaactact ggctctccaa
    41821 aattcttagc taaacaataa atttttgcac aatattcaac ttcttcaaca atattaaatg
    41881 cattcaataa attttgtgca cctgctaaaa ttccatgatt cgctagtaaa actgctctac
    41941 gaccttccat tgctttagct gcattcacag ccaattcttt cgtgccatat gttgcatact
    42001 cagctacccg aacatctttc cctgccactg caatcatata atgactcgct ggaagtggtt
    42061 ctctgagaca agctaatact gttgcataag ttgtatgagc atggataatt gcatcgatat
    42121 catcacgagt ttgatattga atcaaatgca tataccattc gctagatggc aagcgttctc
    42181 cctctacaac atttccatta atatccatca ctacaatatc ggattctttg atttcaaaga
    42241 aatcaatacc cgacggggta attgccatca attgtttttc acgatcgaaa acgctgagat
    42301 tcccacctgt tcctttcgtc aaatctgttt ctactagctt cttaccatat ttaattaatt
    42361 cttgttttac atctgacatc cttgtcctcc tcatatcaaa acactaaata tttttcaatt
    42421 caccaattat ccccccttcc tgcacaaaag ctaagaaggg ggagggaggc aaatttacaa
    42481 actctcaatc tttttaattc ttttgggagt aataactctc taattgtaga aactcctcaa
    42541 taacatggtg agcctcttcc atccctttta attgtcccat agctatgagc tgcacaacaa
    42601 tattccccac agctgtagcc tcagtcaaac ctgtaagaac ctctttacca gttctatcag
    42661 caatcatttg gttaaagtaa ctggctctag cacctcctcc aatcacatat atcctcttat
    42721 aaaccttatg agttagttct tctagtaact ctatcgcttt cctatacgtt tcagctaggc
    42781 tttcataaac aatcttaaat agttgtccat ctgtccactc tctagtttca tgatgataag
    42841 ctagatattc tgtcaaagtc ttgtgcatat cagattctgt tgcaaattca gttgattcag
    42901 tatcaatcag aggaagattt tctttttctt tctccaccat tgtcctaata tcatcaaaag
    42961 aataggcttt ccctcttcgt tcaaatgaac gtcttagttc ctctatgatc cacaaccctg
    43021 tacaattctt cagaaatgta atcactccat ctttaccgac ttcatttgta aatccataac
    43081 tgaaggattc ggtagtaaga agcggtgaag taagttccac tccaaccaaa gaccaagtac
    43141 ctgatgaaat aaataaacta ccttctgtct taggtactga gacaatcgcg cttgctgtat
    43201 catgactaca aacattcaca acaggaatat cgcctaaacc atactccttt tttatccttc
    43261 caagaacatt tccctctgaa acaatctcag gaagtaaaga tgaatccaat tcaaatagtt
    43321 ttaagatatt ctgattccag ttttgactcc taggatcaaa taattgagtt gttgaagcaa
    43381 tgcttttttc tgtagcaaac ttacctgtca agagataatt aaacaaatct ggcattaaaa
    43441 gaatcttatt ggtcttatag aaagagtcag gagattcttg acgtgcctta aagagttgaa
    43501 acaaggtatt tatctccata atctgatttc ctgtctctga atacagtttt tctaattcag
    43561 tcatttcaga tatttccttt aacactccct ttgttctttc atcacgataa tgaacaggtt
    43621 gtaataacag cttaccttca ttatcaatca gtccaaaatc aactccccat gtgtcaatac
    43681 cgatagataa aatcttgtaa ctagtattag ccaagcggat actttcaaga attttagcta
    43741 gtagaaagtc aatatcccaa gataaatgcc cttttactct aataggtaga ttagaaaagc
    43801 gatttatttc ttccattact agtttatttt cagaaaggta accaacgatt gctcttccag
    43861 aagtcgcacc taaatctatt gctaaaaccg cttccatttt tcttctctct tcgtccttga
    43921 ttaactttat tataatcccc acgttttatt ttttcaatat gtgaacgctt acttgaataa
    43981 tgttcaaatg ttaacccaat attcataaaa ataattcaaa ttcctccaat ttgtgctata
    44041 atatagttga aatgataaat taggaggagc ttatgataaa agatgaacgt gtacttgaat
    44101 tgattgaaat tattaaaaag aaaaaaagaa ttgccgtaaa agagctggca gaaatcactt
    44161 tctccagcac aagtacctta cgtcgtgatt taattttctt agaaaatcaa ggtcttatca
    44221 aaagaaagca cggatacgtg accctgtcct ctatgaacac aattgaactt tctcatcaaa
    44281 tacgggaagg agaaagtact aggcaaaaaa gactaatcgc tagtctcgct aaagacttta
    44341 ttcggtctgg tatgtgtgtt tatctggatt ccagtactac tgtctacgaa ctttgtccct
    44401 atctttctga acttgataat ttgattattt ttacaaatgg tttacatact gcacaaaccc
    44461 tatctgaaac tgttaaagat agctccaaaa tctttatcac atctggcgag gtcaaacatc
    44521 aatcctgttc cgtggtcaac tatgataagg aaaattcttt attagatcat tttaatatcg
    44581 atttagcatt ttgttcagca agaggtattg atgaccaata tgtttatgaa gcttctctca
    44641 gccaagctat ttcaaaaaag aatattattg acaaagccca tgaaaccatc ttactgattg
    44701 atagttctaa attttacaag actggatttt ttaaaattaa tcccctctcc aaatacacaa
    44761 cctttatttc agacaccgtg ccagatcaaa aattattaga cgcagtcgaa ttatttgatg
    44821 gagaatgggt ttctgatatt caatgaaaat caaataggaa gctagtctca gcttgctcaa
    44881 agtacagatt tgaaaactga tgaagtcagc tcgaaacact gttttgaggt tgtagataga
    44941 actgatgaag tcagtcacat atatacggaa agacgaagct gacatgatgt gaagagattt
    45001 tcgaagagta ttcgttctgt ctgctgactg atttacaaat attcaccaca tgacattatt
    45061 ttctcagcaa ccctaaaaac agaggctgga caaaaactca atttcaggag aaaatggagt
    45121 aaaccttccc acaataaaac gcatagtatc aagtttttgc acacctgata ttatgcgttt
    45181 ttctgatttt aaagactttg tcgcctagac cctatatttc aagaattaag tgaccttgat
    45241 gatctaaatg tattgtggta tacta
//
LOCUS       DAVBOG010000010        44499 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.010, whole genome shotgun sequence.
ACCESSION   DAVBOG010000010 DAVBOG010000000
VERSION     DAVBOG010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 44499)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 44499)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..44499
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.010"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..218
                     /locus_tag="VQ865_000584"
     CDS             <1..218
                     /locus_tag="VQ865_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3134990.1"
                     /translation="VIIMDNARFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWA
                     HIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            complement(253..1050)
                     /locus_tag="VQ865_000585"
                     /pseudo
     CDS             complement(253..1050)
                     /locus_tag="VQ865_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436304.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            1315..1551
                     /locus_tag="VQ865_000586"
     CDS             1315..1551
                     /locus_tag="VQ865_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecX"
                     /protein_id="HET3134991.1"
                     /translation="MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVR
                     YGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC"
     gene            1782..3068
                     /locus_tag="VQ865_000587"
     CDS             1782..3068
                     /locus_tag="VQ865_000587"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011017279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HET3134992.1"
                     /translation="MTSVVVVGTQWGDEGKGKITDFLSANAEVIARYQGGDNAGHTIV
                     IDGKKFKLHLIPSGIFFPEKISVIGNGMVVNPKSLVKELSYLHEEGVTTDNLRISDRA
                     HVILPYHIELDRLQEEAKGDNKIGTTIKGIGPAYMDKAARVGIRIADLLDKDIFRERL
                     ERNLAEKNRLFEKLYDSKAIVFDDIFEEYYEYGQQIKKYVIDTSVILNDALDNGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKIDKVVGVCKAYTSRVGDGP
                     FPTELFDEVGERIREVGHEYGTTTGRPRRVGWFDSVVMRHSRRVSGITNLSLNSIDVL
                     SGLDTVKICVAYDLDGQRIDYYPASLEQLKRCKPIYEELPGWSEDITGVRNLEDLPEN
                     ARNYVRRVSELVGVRISTFSVGPGREQTNILESVWS"
     gene            complement(3300..4448)
                     /locus_tag="VQ865_000588"
     CDS             complement(3300..4448)
                     /locus_tag="VQ865_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000876726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3134993.1"
                     /translation="MKYNKTKYPNIYYYETAKGKRYYVRRSFFFRGKKREKSKSGFTT
                     LPQARAALVELEQQIQEQELGINTNLTLDQYWDIYSEKRLSTGRWNDTSYYLNDNLYK
                     NHIKAKFGSILLKNLDRNEYELFIAEKLQNHTRYTVQTLNSSFMALLNDAVKNGNLLS
                     NRLKGVFIGQSDIPAANKKVTLKEFKTWIAKAEEIMPKQFYALTYLTIFGLRRGEVFG
                     LRPMDITQNDSGRAILHLRDSRSNQTLKGKGGLKTKDSERYVCLDDIGTDLIYYLIAE
                     ASKIKRKLGIIKEQHKDYITINEKGGLINPNQLNRNFNLVNEATGLHVTPHMMRHFFT
                     TQSIIAGVPLEQLSQALGHTKVYMTDRYNQVEDELAEATTDLFLSHIR"
     gene            complement(4623..5435)
                     /locus_tag="VQ865_000589"
     CDS             complement(4623..5435)
                     /locus_tag="VQ865_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease"
                     /protein_id="HET3134994.1"
                     /translation="MQKTVEKILFRVAGVTKYKKAVKEACNMIAEDNGIPEYAKYYSN
                     LSTKELREELEEYGLKVFKYQDLDFFNIELVPEVDNRYDPNAIKVLIFDNHVGYVPAT
                     IAKTIRKYFDNKKYNFVIEGEIKGGPYKEWDEYEEKVVTNNDLDVGFEIYLTIVDSSQ
                     KEVIQSESSEIIDDNISNKEVTETEAIETKTTETEHIEQNIVSDSVADIVNEINLSET
                     SPKKKLPANKIIFSALYLFLVFFGVVGIPIAPFLAVPLTAWSLYKLYKLFRK"
     gene            complement(5473..5853)
                     /locus_tag="VQ865_000590"
                     /pseudo
     CDS             complement(5473..5853)
                     /locus_tag="VQ865_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170931.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
     gene            complement(5866..6129)
                     /locus_tag="VQ865_000591"
     CDS             complement(5866..6129)
                     /locus_tag="VQ865_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3134995.1"
                     /translation="MYRLDIDKKALKQLKKLDTPTRKQILSWLAKNIENTTNPRQHGK
                     ALKANLAGYWRYRVENYRIICDIQDDKLVVLAVEIAHRRDVYK"
     gene            complement(6129..6362)
                     /locus_tag="VQ865_000592"
     CDS             complement(6129..6362)
                     /locus_tag="VQ865_000592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134996.1"
                     /translation="MTITINFTEKNSYITDYLTKHGIDTTTMDFDDFMVLMEDIEDAR
                     AADQAYMEYLADPATYTMDEVLDELGLSREDIA"
     gene            complement(6362..6730)
                     /locus_tag="VQ865_000593"
     CDS             complement(6362..6730)
                     /locus_tag="VQ865_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3134997.1"
                     /translation="MFVAFDKIKELADKQGISINILEEKLGYGTNTLYRLKRSNPSSK
                     VLKEIADYFNVSADYLLGRTDNPAIAGSDEFAQVNGQIIDLRKAAANTMLFDGKPLNE
                     DDIDFITSVLSAHFKSKGER"
     gene            7015..7161
                     /locus_tag="VQ865_000594"
     CDS             7015..7161
                     /locus_tag="VQ865_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134998.1"
                     /translation="MNEEDLKELLELLATDYGRGYLDGVVGGLSMLLKISKEAEKYRK
                     EKYE"
     gene            7205..7579
                     /locus_tag="VQ865_000595"
     CDS             7205..7579
                     /locus_tag="VQ865_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000573356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3134999.1"
                     /translation="MIETLEIKINKKTYFISARADVPVRYKVMFGRNLFDDFSKIKNN
                     KDETLSLCLLFCMTDKSSEEFCKFFIENNSYITSRHHYEAIRLFEKHFIFKPVTYSLE
                     DIVQILTIYLENTKTQIGGKNE"
     gene            7572..7775
                     /locus_tag="VQ865_000596"
     CDS             7572..7775
                     /locus_tag="VQ865_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3135000.1"
                     /translation="MSKELKIIKAKIKTRLIELDMTQVELAKQVSVASSVISELLKYG
                     KGSDYVKEKVVDILGIENPWENS"
     gene            7792..7989
                     /locus_tag="VQ865_000597"
     CDS             7792..7989
                     /locus_tag="VQ865_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135001.1"
                     /translation="MNNAAQKVTRIDKDAWEIATELANEYGVSICHIISESVRYCAEN
                     AEFKEMDVVVKRLVVGSKVLE"
     gene            8000..8161
                     /locus_tag="VQ865_000598"
     CDS             8000..8161
                     /locus_tag="VQ865_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135002.1"
                     /translation="MNELVWFYFVVIINLIIGFATYYASKRDREKRINGFKKIQDDEL
                     ERVRNKFNL"
     gene            complement(8156..8581)
                     /locus_tag="VQ865_000599"
     CDS             complement(8156..8581)
                     /locus_tag="VQ865_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000456432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135003.1"
                     /translation="MEYQALIQPVISIILAIISGLWSYVASKANNKAEIEKQAKEHSH
                     TVEKLEREFHHQIDTLKQQHAFELEKIKQAHELRLQELEKVSQLDTETDKSMKMNDLT
                     YKVFTGEVDFDKALKIANKASNSKQNLNKRFIQKTSKKS"
     gene            8635..9348
                     /locus_tag="VQ865_000600"
     CDS             8635..9348
                     /locus_tag="VQ865_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ORF6C domain-containing protein"
                     /protein_id="HET3135004.1"
                     /translation="MNEIFNFHGQEVRTLIIDDEPWFVGKDVADILGYSKARNAIALH
                     VDEDDALKQGLTDNLGRVQETIIINESGLYSLILSSKLPQAKEFKRWVTSEVLPAIRK
                     QGGFIREDLDEDAFIALFTGQKKLREQQATMLEDIDYLKSEQPIHPSYAKSLLKKRKA
                     RVVVCLGGIDSPAYADKTFAQSVFRQAEIDFKDHFNINRYDLLPKKFADAALAYWMTW
                     EPSTNTKMKIMKLNSFDEG"
     gene            9361..9618
                     /locus_tag="VQ865_000601"
     CDS             9361..9618
                     /locus_tag="VQ865_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3135005.1"
                     /translation="MDNVLLSLSEWIKSIIKDTITRLVEIEKDSDHYPELMDVNTTCD
                     FLGIKYATFSDNYRYLKGFPKELPGKKWSKRAIKEWLSNQI"
     gene            9704..10024
                     /locus_tag="VQ865_000602"
     CDS             9704..10024
                     /locus_tag="VQ865_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135006.1"
                     /translation="MFEPPILDQLMGVGALLLGFAGACRHIKLQEQRKEEERREEQEF
                     ASMIIQVRNHAYERGREDKWQEIRKNIRREFKGFTYDNEPPVGLRPEPLALPEPKQSA
                     IRFL"
     gene            10040..10336
                     /locus_tag="VQ865_000603"
     CDS             10040..10336
                     /locus_tag="VQ865_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135007.1"
                     /translation="MQELIESLDNLIMIVKELEGRESTSRHFITIWENDYKNLLRVKE
                     YLTDYEKLAKDYRYMTLKNKLLKIEKMELEGRYIYEDMRMKYRANRRKWGARYV"
     gene            10329..11156
                     /locus_tag="VQ865_000604"
     CDS             10329..11156
                     /locus_tag="VQ865_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage replisome organizer N-terminal
                     domain-containing protein"
                     /protein_id="HET3135008.1"
                     /translation="MSEIKWIKIKTDIFDDEKMCLIDASPDRDAIIVIWIKLITLAGK
                     LNTKGVLTISKNIVYTDEMLAQTFHRPLNTVRMALEVFEKFGMVEKIDGVIMLPNWEK
                     HQNIDGMEKIKEQNRNRAARHRQKQKLLAQNNESNVTDNVMDNVTVTHGNALDKELDK
                     DIEINNNKVMISSSLSENLKNSGIHLTDKSHQQLLDYVGLDGMSFDMLNRAVEKTSGS
                     HKPSFNYLIAILESWKKKGFTSIEQVDEDDRKYKEGKKSRQQNDKTSEQEVRDEWGF"
     gene            11144..11302
                     /locus_tag="VQ865_000605"
     CDS             11144..11302
                     /locus_tag="VQ865_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135009.1"
                     /translation="MGILELIEQFEIDYYPLSYEKKTLLADQPIHPVVACLSEMASWH
                     ECGGRLVW"
     gene            11296..12066
                     /locus_tag="VQ865_000606"
     CDS             11296..12066
                     /locus_tag="VQ865_000606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000228202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3135010.1"
                     /translation="MVDNVFEEIALSYRRNTEQQEEFCEKHNIPLIKILRTESVVCRM
                     CESERIHEENQERVNELANAENERERKYYLEKFSLYDEILKNATLDNFETPTEKEAEK
                     LAFAKRICREWSEGARNNIVLQGEAGTGKSHLAFAMVKALSEYTKEIAIFINVTDLLM
                     KIKADFSQEEFLVNKIASAKFLVLDDLGMEKDSEWSFTILYNILNKRSNTIITTNLIS
                     ADIQKRYGRPFMSRLMKGVDKDHLMVFNDLTNKRKQYF"
     gene            12081..12275
                     /locus_tag="VQ865_000607"
     CDS             12081..12275
                     /locus_tag="VQ865_000607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135011.1"
                     /translation="MFILKHGTREDKPFLRSAIISVTGLDISCSEEKKAMRFISRAAA
                     LQVSKALRGSFGNFYPVEVE"
     gene            12275..12502
                     /locus_tag="VQ865_000608"
     CDS             12275..12502
                     /locus_tag="VQ865_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135012.1"
                     /translation="MLELYFVYNGHCKFFLGRFDNVDDLIEQMEDHQWAFSAITHPRF
                     QKHIGQRTTRFDYGSKDCYYLATFSGGEKND"
     gene            12629..12796
                     /locus_tag="VQ865_000609"
     CDS             12629..12796
                     /locus_tag="VQ865_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135013.1"
                     /translation="MVGVTYQEIHLFVEFLKEQYGQGRPDYIEALNDLDGLVEVSYRE
                     AIERFLEDEVR"
     gene            12783..12992
                     /locus_tag="VQ865_000610"
     CDS             12783..12992
                     /locus_tag="VQ865_000610"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135014.1"
                     /translation="MKYDKQAEIDGLKRTIEQNEEKIIEYSKPCDARKRRIRALERDL
                     LRKKNKELRRKAEELEYDGRVKAKS"
     gene            12964..13293
                     /locus_tag="VQ865_000611"
     CDS             12964..13293
                     /locus_tag="VQ865_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135015.1"
                     /translation="MMEELKQKVNEVYNWTVEDGKPQPPKQDLPQAVKDRADYFWEMA
                     EDGMTFMGAMECIFADEKPTDYDLGATKGWLPKSKEFDDWVGYSPSMSQLVIAVYLIY
                     RGSEDET"
     gene            13283..13708
                     /locus_tag="VQ865_000612"
     CDS             13283..13708
                     /locus_tag="VQ865_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1642 domain-containing protein"
                     /protein_id="HET3135016.1"
                     /translation="MKLNELIKKYKKLEGVWNAEGAELVRQIFLQDLEQLDKPQPVKV
                     PQCVAEYIEFKKKNNFHVYGLAWLNGYEVEKEKRYFVKIKGNIKENMLVYGELLKRYF
                     FTKSFSLDDVIYSHTRKELEAANFGWVFDCPGIEIEEVE"
     gene            13708..14222
                     /locus_tag="VQ865_000613"
                     /pseudo
     CDS             13708..14222
                     /locus_tag="VQ865_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502465.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
     gene            14219..14608
                     /locus_tag="VQ865_000614"
     CDS             14219..14608
                     /locus_tag="VQ865_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000612387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135017.1"
                     /translation="MIPKFRVWHHELGRLMSVKCMFFQDSEIEEFELNDALMNDYITA
                     YPDEIELMQSTGLKDKNGKEVFIGDIVKCTRGCLHEVYLEKEYGGTFIGGMPAVYLKG
                     LGDGYAWTEYEEIIGNIYENPELLEDK"
     gene            14608..14844
                     /locus_tag="VQ865_000615"
     CDS             14608..14844
                     /locus_tag="VQ865_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3310 domain-containing protein"
                     /protein_id="HET3135018.1"
                     /translation="MNPEIIDNINKPSHYQGANGLEAIDVVHNFVGSLSGASAFFWGN
                     AIKYMLRFQKKNGLEDLKKARKNLDWLIEEMEHE"
     gene            14841..14999
                     /locus_tag="VQ865_000616"
     CDS             14841..14999
                     /locus_tag="VQ865_000616"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135019.1"
                     /translation="MNTHCMKATPLLPWGRLRKSAKKQELLNGASISEFAIEDICTFF
                     GIEIQERK"
     gene            15211..15612
                     /locus_tag="VQ865_000617"
     CDS             15211..15612
                     /locus_tag="VQ865_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000736386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3135020.1"
                     /translation="MKKLSDEELKTLDRELFKFQNIQRTIDLRRLELETRNPDAQSGP
                     TVGISKPTETIAIRIADDPTLKFLEGFKGIINKLLSNLVEEDKEIFNLRWRYPQLRWE
                     EIAEQKFMSKATIYRRRRIILEQYAIMKGEL"
     gene            15801..16343
                     /locus_tag="VQ865_000618"
     CDS             15801..16343
                     /locus_tag="VQ865_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000397549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3135021.1"
                     /translation="MEFVSPIKDNDNIQAMKDYLREWNEMYYMLFITGLNTGLRVGDI
                     LTLKVKDVQGWHIKLRERKTGKQITRRMTKELKKEMRRYVEGKPFHHFLFKSRQGQNK
                     AITRERAYQIIHEAAEELGIDNVGTHTMRKTFGYKYYNKTKDVGTLQKMFNHSSPAIT
                     LRYIGIEQAELDDALRNFVI"
     gene            16507..16698
                     /locus_tag="VQ865_000619"
     CDS             16507..16698
                     /locus_tag="VQ865_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135022.1"
                     /translation="MVKEYRDDFLGEKAFEKLNKDIDANPEVGFEIVGYTQTAFVNGM
                     HIPLTAILVKWNNFFKESE"
     gene            16818..17138
                     /locus_tag="VQ865_000620"
     CDS             16818..17138
                     /locus_tag="VQ865_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HET3135023.1"
                     /translation="MYNKPIRPSLKSKKWEKFRDRIMRKHDYLCQESLRYGISVQAEM
                     VHHIFPVSEYPELEFVEWNCLPLTNKKHNTFHDRVNDRVINQGLYWQKKRKKEFLNFF
                     KNEK"
     gene            17276..17668
                     /locus_tag="VQ865_000621"
     CDS             17276..17668
                     /locus_tag="VQ865_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P27 family phage terminase small subunit"
                     /protein_id="HET3135024.1"
                     /translation="MAKPITAKSIKSKVVKQMKDLGTYRKEFEMIIDIFAGMLYQYQK
                     LAQDYADMGYPVTDTYVNKAGAENERKVPILTAMEILRKDILSYSNQLMMNPKSLGEV
                     VEQEGESVLTEVLKFKNEIKKKRVTGNG"
     gene            17661..19391
                     /locus_tag="VQ865_000622"
     CDS             17661..19391
                     /locus_tag="VQ865_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HET3135025.1"
                     /translation="MGNLDKAKKYAQHVLTHREEHCEENILAAERFFRDLENPTFEMD
                     EDMVDFVIHFIENVIVHQQGDDMFAVSIRNKPLLLQPWQHFVVVNLFGFYYKGTNERR
                     FKEALIMLARKNGKTSFTAAIALAYQILDTDSGSKCYIVANSVKQAMEAFGFLRFNVE
                     RWNDKNIRIKDNNQEHSITANFGDEGSFFIQALANDESRLDSLNGNVIILDEAHTMRN
                     SKKHGLMKKTMSAYRNSMLFVISTAGDIPTGFLANRLKYCQKVLKQLVTDDSFFIFIC
                     KANQSADGDVVNYLDENILKMANPSWGVTVSLKALKEEAEQAMNDPQTRNEFFNKTLN
                     IFTNSMNAYFNPDEFIASDSCYDWSLEELARLPIRWYGGADLSRLHDLTAAALYGVYH
                     DGEKDVDICITHAFFPRINAQKKANDDGIPLFGWQSDGWLTMSNTPTVLYDDIVKWFI
                     KMREKGFKIAAVGMDRKFGREFLTKMKQARFKMIDQPQLFYLKSEGFRRIEFKVKNKE
                     FYYLHSDAYEYCVSNVRAIEKVDDAVQYEKLDGDGGTARIDLFDASVFACIQALANLG
                     KGGDVMRFFD"
     gene            19399..19617
                     /locus_tag="VQ865_000623"
     CDS             19399..19617
                     /locus_tag="VQ865_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135026.1"
                     /translation="MNEIVLSEHEINLLINKGRVKVILNGEVVTIRQRHMKNLMAETV
                     KWEKQVIDVSQNIVRNKHFDSLFQNTFR"
     gene            19635..20837
                     /locus_tag="VQ865_000624"
     CDS             19635..20837
                     /locus_tag="VQ865_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HET3135027.1"
                     /translation="MGIFEKFWKRNKPSKSINMLSHSDLGLSNLMDSYVPLARNPDVV
                     TAVNKIADLVSNMTIHLMENTDKGDIRIRDGLARKIDINPCKHMTRKSWIFKIVRDLL
                     LYGDGNSVLHVEYEPVTDYISNLRPFPMREVSFQTDKDSYVISFRGEEYSPDEVVHFV
                     INPDPDIPYIGTGFRVTLTDVVQSLNMATKTKKSFMNGKNIPSLIVKVDSSSAELDSE
                     QGRERIAEKYLSTSRVGAPWIVPEALLDIQQVKPLSLTDIALNESVELDKRTVAGLLG
                     VPAFILGVGEFNKTEYNNFVNTTVMSIATTITQTLTRDLLLSSNRYFKLNPRSLFSYN
                     ITELSAVAQQMANSAAMRRNEWRDWLGMAPDPEMEELIVLENFLPQEKLGDQNKLKGG
                     EEENAKAK"
     gene            20821..21396
                     /locus_tag="VQ865_000625"
     CDS             20821..21396
                     /locus_tag="VQ865_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HET3135028.1"
                     /translation="MQKRNSYRATQFQTREEESGDLILSGYFIKFDEETELWPGYCEV
                     IKRAGVEKAVTDADIRALFNHDDSLVLGRTGNGTLTLGVDDVGLFGDIIINKDDPQAV
                     GAYARVKRGDVIGCSFGFIPVKIETEEREDGSYLDTVLELEIFEVSPCTFPAYPQTEI
                     AARQKDFESQKRANREALDKRKKEIKEKFNL"
     gene            21393..22565
                     /locus_tag="VQ865_000626"
     CDS             21393..22565
                     /locus_tag="VQ865_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HET3135029.1"
                     /translation="MNKLLILGARMRNKADKVVELEESIKELNKRSELEAKKLEQAGT
                     DEEVSAVEKNLEDIQKESDEKEAEKEQLEKEIEDLKNQVEELNRKAPTYPSQEKRGGQ
                     KLERRDAIAKYIRTGQTRDIVGLKTTDSGSAALIPTEVLKPHFVNKTRNPLLDLVERV
                     KVNSGSGKYPVIKKTDGVMVSIDELKSNPELGKPAISEIDYSIKTYRGYVPVSQEMID
                     DADYDIMSIVEDEVFNQGDNTELSLVTAVLKTATQADAAGFDGIKDIYNKKLKSIYKA
                     SIVVTKSMFAALDKVKDKDGRYMLQTDVASPTGYSFGGKTIYKVDDTVFGNEGDMKFF
                     IGDVTEFVKEFDRSQVSVKWVNNDIYGQLLGLFIRLDIKKADEEAGFFGTYTDVVA"
     gene            22577..22867
                     /locus_tag="VQ865_000627"
     CDS             22577..22867
                     /locus_tag="VQ865_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135030.1"
                     /translation="MSYKVIRPFKDLADPENHDYAVGDIFPREGYEPTDSFTNGLLTG
                     ANTAGSIFLEVLGDDEPKKPAPETKEVKEEPAVEQEETVEETAEESAEEVEE"
     gene            22870..23151
                     /locus_tag="VQ865_000628"
     CDS             22870..23151
                     /locus_tag="VQ865_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000371962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail connector protein"
                     /protein_id="HET3135031.1"
                     /translation="MDQGQLLELLKLKLGISTDLRDKPLKKIISSVITELTDNLGIEL
                     VGERADHEMFIVDYAAYRYEGGVDMPRHLQWRLHNLQIASKKEVKNVES"
     gene            23138..23437
                     /locus_tag="VQ865_000629"
     CDS             23138..23437
                     /locus_tag="VQ865_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000267058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HET3135032.1"
                     /translation="MWNHEITLISKKVTGKDKLLQPISEDVEVTLLCRKKRVTRSEFY
                     QANQVGLKPSLVVEIRNFEYENQELAKFEGKQYHILKTYPIDSEILELTLSEVLK"
     gene            23434..23781
                     /locus_tag="VQ865_000630"
     CDS             23434..23781
                     /locus_tag="VQ865_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HET3135033.1"
                     /translation="MSNDLADLIAKELAAYSDEVTEEVDKIAEQVTDETVDELKETSP
                     KRYGKYRRSWKKKKLANGSFVVFNAVASLTHILENGHLSRNGGRVAGIVHIKPAEEKA
                     IQNFEKRIKEIGK"
     gene            23778..24101
                     /locus_tag="VQ865_000631"
     CDS             23778..24101
                     /locus_tag="VQ865_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135034.1"
                     /translation="MKLSDFAAILEQANLPVTYRAFKIGNAPDLPYLVYYESSPVINS
                     ADNTVNHQIKSVTVELAFESKDEDLEERLEELWANHKLFFEVQEETFIETERLYVKSY
                     TVYLY"
     gene            24113..24691
                     /locus_tag="VQ865_000632"
     CDS             24113..24691
                     /locus_tag="VQ865_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3135035.1"
                     /translation="MTQENKVTFGLENVHIAPIKTLAADGVITYGDVFRFPGAIELIL
                     DTKGETTPIKADNKDYHFMNSNEGYEGKLKIPHIIDEFATKILGEIKDPQTGVMTEKA
                     DASLTEFAMMFQFEGDKNKTRYVMYYCFASRPSLGSKTKNGTSTNERELSFKASPRPL
                     DTVVKRSITSADDKDAYDNWFKKVYEPTAVAA"
     gene            24703..25122
                     /locus_tag="VQ865_000633"
     CDS             24703..25122
                     /locus_tag="VQ865_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003047255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135036.1"
                     /translation="MRKIVLVGDQEYELGTNGYTPIAYKQQFGKDYFQDLFSMLKNQS
                     FMNELNKLETDKELTATNIDISMLSDFDMTFFNRLFWTFAKSANPHIKPYEQFFMEME
                     IFPIQEVGPVLMEMLNASMTTKKHQMSQNQLAKKSSQ"
     gene            25400..28159
                     /locus_tag="VQ865_000634"
     CDS             25400..28159
                     /locus_tag="VQ865_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000918321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HET3135037.1"
                     /translation="MAGNIKGIKIEIDGDTQPLQKALKNVNKAATDASQELRQIDKAL
                     KFDTGNVTLLTQKQEVLQKQVSTTKEKLETLRQAQSQVEQQFKNGDIGADQYRAFQRE
                     VEVTQNVLKGYEGKLANVNQALNENGSATQNNKNQLKELQNEQSQLASEMSKVTSSFK
                     LQESALGSNASEAERNALAQKKIGAQSEIVSKQISNLEQQLEITKKEFGENSTQANKM
                     ESELNQAKTAFNHLNDEMKGTKSAADSTQESLSEISRNLRAELLQQFSEKLSAISEKL
                     VEVGKEALEAAAQMQASNAQFTTVFGDMETQAREALNAIGQEMDIVPERLQGSFTQMA
                     SFAKTSGLDTAQALDLTSRATRAAADGAAFYDKSIESVSESLQSFLKGNFANDAALGI
                     SATETTRNAAANKLYGKSFKDLSEAQKQLTLLQMVEDGNKLSGALGQAARESDGLENV
                     MGNLKQAGTNALSAIGQPLLEMMIPVFQTLATIVKGVAELFNSLPDPVKDFVVILGTV
                     VTAVGVIAPIFLTLQALAEFLKISIGEMIIAALPIIGTAIAIAAAVAAIIVIVKYLWE
                     TNEGFRDAVTTVWNAILAVINTVVSEISDFIMSIFGTVVTWWTENQELIRTSAETVWN
                     AIYTVISTILDILGPLLQAGWDNIQLIITTTWEIIKIVVETAINVVLGVIQAVMQIIT
                     GDWSGAWETIKGVFSTVWQAIQSIVQTIFSAIQSYISNILNGISGTVSNIWNSIKDTV
                     SNVLNAISSTVSSVWEGIKSTISSAINGARDAVSSAIEAIKGLFNFNISWPHIPLPHF
                     YVSGSANPLDWLSQGVPSIGIEWYAKGGIMTKPTIFGMNGNNIMVGGEAGNEAVLPLN
                     DKTLGAIGRGIAQTMGGTSPTINITITGNTVREEADISRIADEVAQRIADELQRRRQL
                     RGGFA"
     gene            28156..28878
                     /locus_tag="VQ865_000635"
     CDS             28156..28878
                     /locus_tag="VQ865_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3135038.1"
                     /translation="MIKHNELVIDGVRTSSFPFKIIVHDSPSIALGESKTALLEHGGV
                     SGAIVQTNKHRELVKKTYTIYLVKPTEEQMNQFMSLFIREKFWLESERVKTTRLWCYK
                     VNVSDLEEVQPGLYMTKATFTCHPTKYFKDSDTQRLTRSGTLTVQGSALAFPKITIVG
                     QSASETSFTIAGQVIRLERLTESLVMVNNPDNPSFKTTTGKPVKWSGDFITVDPAKVK
                     NIGVVLGPGIQSIEIETVWGWA"
     gene            28879..32100
                     /locus_tag="VQ865_000636"
     CDS             28879..32100
                     /locus_tag="VQ865_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002644521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HET3135039.1"
                     /translation="MLYLLNKDVRTVRWNGEPLHEATSAIVKETMNGDFTLTVKYPIS
                     DSGIYQLIQEDMLIKAPTPVLGAQLFRIKKPVEHNDHLEITAYHISDDVMQRSITQMS
                     VTSQSCGMALARMVQNTKTALGDFSFNSDIQDRRTFNTTETETLYSVLLDGKHSIAGT
                     WEGELVRDNFAMTVKKSRGENRGVVITTHKNLKDYQRTKNSQNVVTRIHARSTFKPEG
                     AEKETTIRVTVDSPLINSYPYINEKEYENNNAKSVEELQKWAQSKFSNEGIDKVSDAI
                     KIEAYELDGQVVHMGDTVNLKSWKHNVDAFKKAIAYEFDALKEEYISLTFDDKAGIGG
                     SRSSGGLSSAADAILGVTESAQEIALEKALQNADLDFDHKAGLLRQEISDDIELAKAR
                     AEEVKRELSDTINQRFNSFDNGPLKETKRKAEEALRNAGASTLLAQEAKRIGLDSVAR
                     LEAFKSQTTSAQTALSGDLDALKRTIANDIRPKQAQAEAEIAKQAEALSRTKNELAGA
                     STLLAQEAKRIELDSVARLEAFKSQTTSAQTALSGDLDVLKQTIANDIRPKQAQAEAE
                     IAKQVEALSRTKNELAGVKSAQATYKETTTRRLSELTNLANGKASKSELTQTAEELAS
                     RIASVQAGSSRNYFRNSRSRTFTTGGQAVYDYRTFIVPDFWKNSDRFKRDYVRISFDV
                     TFPVALVNDMPAMVHFSAHPWYAYRNLIFKGGTVERQHFEFTIDLSSSSEDYQTNNVF
                     IRFGTNYGFPAGLQVVIENAMLSVGNYFPAYQPAYEDQEDRVSVVESNFKQRADSLDA
                     GVRSLTEGLRTKADISSLNVTAENIRQSVKSLETDTQNKLNQKLSQAEFEVRAGSIRQ
                     EILNATKDKASKSELTQTAEELASRIASVQASGRNLFLNSLFKQDIPKTGIWTTSTYT
                     ATIDSESKYLGHKALKIIGLNPSGRDGGNPKVTYPALGQFGKVIPGSTTNQDVTISFY
                     AKANKNGIMLRSRLGNIGYKTGNVTLSTEIKRYVVHIPKGWTNESKQTTNEWLFNFNQ
                     EGTIWIWMPKFEISDVDTSYSEAPEDIEGQISTVESTFKQRAN"
     gene            34096..35478
                     /locus_tag="VQ865_000637"
                     /pseudo
     CDS             34096..35478
                     /locus_tag="VQ865_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001838376.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
     gene            35459..35662
                     /locus_tag="VQ865_000638"
     CDS             35459..35662
                     /locus_tag="VQ865_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001091107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135040.1"
                     /translation="MNTEQLNQALQMTIREMSTTSTDSMIASNFLSIQLNEQREENQR
                     LQARVDELEALLDEQTKPADKGE"
     gene            35665..36017
                     /locus_tag="VQ865_000639"
                     /pseudo
     CDS             35665..36017
                     /locus_tag="VQ865_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861592.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            36027..36443
                     /locus_tag="VQ865_000640"
     CDS             36027..36443
                     /locus_tag="VQ865_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HET3135041.1"
                     /translation="MQIEFFNFLRSVVQTEDGLVLYALALIVSMEIIDFVTGTIAAII
                     NPDIEYKSKIGINGLLRKISGVLLLMILIPASVLLPEKTGFVFLHSIYLGYIAFTFQS
                     LIENYRKLKGNVTLFQPIVKVFQRLLEKDDDTKKGE"
     gene            36447..36782
                     /locus_tag="VQ865_000641"
     CDS             36447..36782
                     /locus_tag="VQ865_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001186237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HET3135042.1"
                     /translation="MQQITEIITNGAISILVILAGVVVRVVKEYLVKKGGEKTIKIVE
                     ILAKNAVNAVEQVAAETGYKGDEKLAQARAKIRAELTKYNISMTDKDLDTFVESAVKQ
                     MNDAWKGQE"
     gene            36782..37738
                     /locus_tag="VQ865_000642"
     CDS             36782..37738
                     /locus_tag="VQ865_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3135043.1"
                     /translation="MDIDRNRLRTGLPQVGVQPYRQVHAHSTGNRNSTAQNEADYHYR
                     KDPELGFFSHVVGNGRIMQVGPVNNGSWDVGGGWNAESYAAVELIESHSTKEEFMADY
                     RLYIELLRNLADEAGLPKTLDTGSLAGIKTHEYCTNNQPNNHSDHVDPYPYLASWGIS
                     REQFKQDIENGLSAATGWQKNGTGYWYVHSDGSYPKDKFEKINGTWYYFDGSGYMLSD
                     RWKKHTDGNWYYFDQSGEMATGWKKIAEKWYYFDVEGAMKTGWVKYKDTWYYLDAKEG
                     AMVSNAFIQSADGTGWYYLKPDGTLADKPDFTVEPDGLITVK"
     gene            complement(38008..38187)
                     /locus_tag="VQ865_000643"
     CDS             complement(38008..38187)
                     /locus_tag="VQ865_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135044.1"
                     /translation="MREVIQELLDSSMSTSAISQGAGVPWTTVSDLRKGKTSMDKMAL
                     LTAEKLYEFATTDKQ"
     gene            complement(38329..38478)
                     /locus_tag="VQ865_000644"
     CDS             complement(38329..38478)
                     /locus_tag="VQ865_000644"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135045.1"
                     /translation="MNKEDWLRLLEKAIDNIPETVTAIASLVTAITVARQNKKRKPKS
                     RQRKR"
     gene            38760..39227
                     /locus_tag="VQ865_000645"
     CDS             38760..39227
                     /locus_tag="VQ865_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deaminase"
                     /protein_id="HET3135046.1"
                     /translation="MYYTLEEKEVFMREALREAEIALEHDEIPIGCVIVKDGEIIGRG
                     HNAREELQRAVMHAEIMAIEDANLSEESWRLLDCTLFVTIEPCVMCSGAIGLARIPNV
                     VYGAKNQKFGAAGSLYNILTDERLNHRVEVEIGILEDECAAIMQDFFRNRRKK"
     gene            39260..39357
                     /gene="ffs"
                     /locus_tag="VQ865_000646"
     ncRNA           39260..39357
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="VQ865_000646"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            39414..39857
                     /locus_tag="VQ865_000647"
     CDS             39414..39857
                     /locus_tag="VQ865_000647"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HET3135047.1"
                     /translation="MKIRGFELVSSFTDENLLPKRETAHAAGYDLKVAVRTVVAPGEI
                     VLVPTGVKAYMQPTEVLYLYDRSSNPRKKGLVLINSVGVIDGDYYGNPGNEGHIFAQM
                     KNITDQEVVLEVGERIVQAVFATFLIADGDAADGVRTGGFGSTGH"
     gene            39859..40374
                     /locus_tag="VQ865_000648"
     CDS             39859..40374
                     /locus_tag="VQ865_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3135048.1"
                     /translation="MKIIFVRHGEPDYRELEERSYIGFGIDLAPLSEMGRQQVQKLSK
                     NPLLSSAEIIVSSAVTRALETASYVVCATGLPLRVEPLLHEWQVYKTGIENFETARRL
                     FLENKGELLPNSPIQYETATEMKSRFLECMSKYREHQTVVVVAHRMLMRQFVPNEKID
                     FCQVIECELEI"
     gene            40388..41749
                     /gene="radA"
                     /locus_tag="VQ865_000649"
     CDS             40388..41749
                     /gene="radA"
                     /locus_tag="VQ865_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000336571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HET3135049.1"
                     /translation="MAKKKATFVCQNCGYNSPKYLGRCPNCGSWSSFVEEVEVAEVKN
                     ARVSLTGEKTKPMKLAEVTSINVNRTKTEMEEFNRVLGGGVVPGSLVLIGGDPGIGKS
                     TLLLQVSTQLSQVGTVLYVSGEESAQQIKLRAERLGDIDSEFYLYAETNMQSVRAEVE
                     RIQPDFFIIDSIQTIMSPEISGVQGSVSQVREVTAELMQLAKTNNIAIFIVGHVTKEG
                     TLAGPRMLEHMVDTVLYFEGERHHTFRILRAVKNRFGSTNEIGIFEMQSGGLVEVLNP
                     SQVFLEERLDGATGSSIVVTMEGTRPILAEVQALVTPTMFGNAKRTTTGLDFNRASLI
                     MAVLEKRAGLLLQNQDAYLKSAGGVKLDEPAIDLAVAVAIASSYKDKPTNPQECFVGE
                     LGLTGEIRRVNRIEQRINEAAKLGFTKIYVPKNSLTGITLPKEIQVIGVTTIQEVLKK
                     VFA"
     gene            41822..42319
                     /locus_tag="VQ865_000650"
     CDS             41822..42319
                     /locus_tag="VQ865_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase"
                     /protein_id="HET3135050.1"
                     /translation="MSYFEQFMQANQAYVALHGQLNLPLKPKTRVAIVTCMDSRLHVA
                     QALGLALGDAHILRNAGGRVTEDMIRSLVISQQQMGTREIVVLHHTDCGAQTFENEPF
                     QEYLKEELGVDVSDQDFLPFQDIEESVREDMQLLIESPLIPDDVIISGAIYNVDTGSM
                     TVVEL"
     gene            42344..42538
                     /locus_tag="VQ865_000651"
     CDS             42344..42538
                     /locus_tag="VQ865_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135051.1"
                     /translation="MKKSSILLLCIGLQYETIYYTDGSRSGAEYGLMGISIFLALFYM
                     IPALYFLFRIGKNGNCQRRF"
     gene            42520..43143
                     /locus_tag="VQ865_000652"
     CDS             42520..43143
                     /locus_tag="VQ865_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrsW family intramembrane metalloprotease"
                     /protein_id="HET3135052.1"
                     /translation="MPKKVLILSLLGGMFLSGWLSSFANTYIHDLLGVLFPDSTFLNA
                     FESAIVAPLVEEPLKLLPLVFVLALIPVRKLKSLFLLGIASGLGFQMIEDIGYIRTDL
                     PEGFDFTISRILERIISGIASHWTFSGLAVVGVYLLYRAYKGQKVGKKQGLIFLGLAL
                     GTHFLFNSPFVELETELPLAIPVVTAIALYGFYHAYCFVEKHNELMT"
     gene            43288..44256
                     /locus_tag="VQ865_000653"
     CDS             43288..44256
                     /locus_tag="VQ865_000653"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3135053.1"
                     /translation="MSFSDLKLFALSSNKELAERVAQEIGIELGKSSVRQFSDGEIQV
                     NIEESIRGKHVFILQSTSSPVNDNLLEILIMVDALKRASAESVNVVMPYYGYARQDRK
                     ARAREPITSKLVANMLEVAGVDRLLTIDLHAAQIQGFFDIPVDHLMGAPLIADYFERR
                     GMVGSDYVVVSPDHGGVTRARKLAEFLKTSIAIIDKRRSVDKMNTSEVMNIIGKVEGK
                     TCILIDDMIDTAGTICHAADALAEAGAVEVYASCTHPVLSGPATDNIQKSAIKKLVVL
                     DTIYLPEERLIDKIEQISIAHLLGDAIVRIHEKRPLSPLFDIEKKI"
     gene            complement(44393..44499)
                     /locus_tag="VQ865_000654"
                     /pseudo
     CDS             complement(44393..44499)
                     /locus_tag="VQ865_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT        13873 a         7643 c        10189 g        12794 t
ORIGIN      
        1 cggttattat tatggataat gcaagattcc atagaatggg gaagttagaa cttttatgcg
       61 aagagtttgg gcataaactt ttacctcttc ctccctactc acctgagtac aatcctattg
      121 agaaaacatg ggctcatatc aaaaagcacc tcaaaaaggt attaccaagt tgcaatacct
      181 tttacgaggc ttttttatcc tgctcttgtt tcaattgact atattagagg cgagacattt
      241 ttcggttctt tgtcaactgt agtgggttga agaaagcgaa gatctagaaa ggacaaattt
      301 cgtcctttct tttttgaagt tttcaaagtt cctaaaacca aaggcattgt gcttgataag
      361 tttgatgaga ttattggtgg cttccagttt ggcgttggaa taaggtaatt gaagggcgtt
      421 gacgattttc tctttatctt tgaggaaggt tttaaacaga gtctgaaaaa gaggtggaaa
      481 agcaagagct gatagagatt atagtggtgt ttcaagtctt cggaatagct caaaagttta
      541 tctagaattt ctttattagt caagtgcata cgaaaagtag ggcgataaaa tcgtttatca
      601 ctcagtttct gactatcttg ttgaatgagc tttcagtatc gcttgatagc cttgtattca
      661 tgggatttcg gatgatggct tgtgttctgc tctcaagaac agttatgata ttgagcttat
      721 caaagtcttg agcaataaag ctcatttcca tctcccgatt gaaacagtca ctccccggac
      781 tgtttcaacg tcctaggaca taatctcagg aagacgcgaa aaatcatgct caaagtgaaa
      841 atcattgttc ttgcgaatga cagttgaagt tgaaatagac aactgatgat caatgtcggt
      901 catagaagtc tttttaatta gcttctgagc aatcttttgg ttgatgatac aaggaatttg
      961 atgattcttc ttgacgatag aagtttcagc gaccatcatt tttgaacagt gatagcactt
     1021 aaaacggcct tttctaagaa gaattctagt ttgaattttt tatactagaa aatcagaacc
     1081 ataataccta tataaaaata ttatagttct aataggattt acccaaaagt tttaaggcgg
     1141 tctttttaga actttaatcg tttgaaattt aggtagcaaa tttgtttcta ttttgtcaac
     1201 ttttcctatt tttatcttgt tgaggctggt attttaacaa ttcaggaatt gatagtgaat
     1261 gtgtaaaatt ttttgttaga ataagtttat aaaaaagaaa aggagtattt gattatgtta
     1321 caaaaaattt atgagcagat ggctaatttc tatgatagta ttgaagaaga gtatggtcct
     1381 acatttggtg ataattttga ctgggaacat gttcatttta aatttttaat ttattattta
     1441 gtgagatatg gcattggttg tcgtagggat tttatcgttt accattatcg tgttgcttat
     1501 cgtttgtatc ttgaaaaatt ggtaatgaat cggggtttta tttcttgttg aggtaatttt
     1561 agtaaatttc cgaactaatt tactctttta tggaaagata atagtaaata gctagtaatt
     1621 tttctaaatc attttttaat agttggaaat agcaaatctt tctattgttt cttcttgata
     1681 aaaaggcgat tttttattat aataaattgt aagatataat tgcaggtgag agtcctgcca
     1741 tgtatgtgag aaaggaagag cctgagggct cagacaaaat tatgacttca gttgttgttg
     1801 taggtaccca atggggtgat gaaggtaaag ggaagattac agacttcctt tcagcgaatg
     1861 cagaagtgat tgcacgttac caaggtggtg ataatgctgg tcacacgatt gtgattgacg
     1921 gtaagaaatt taagttgcac ttgattccat ctgggatttt cttccctgaa aaaatatctg
     1981 tcattgggaa tggtatggtt gtaaatccta aatctcttgt aaaagagttg agctatcttc
     2041 atgaggaagg tgtaacaact gataacttac gtatttctga tcgtgcgcat gttattttgc
     2101 cttatcatat cgagttggat cgcttgcaag aagaagctaa gggcgacaat aagattggta
     2161 cgacaattaa gggaattggt ccagcttata tggacaaggc tgctcgtgtt ggaattcgta
     2221 ttgcagatct tttagataaa gatattttcc gtgagcgttt agaacgtaac cttgctgaaa
     2281 agaatcgtct ttttgaaaaa ttgtatgaca gtaaagcgat tgttttcgat gatatttttg
     2341 aagaatatta cgaatatggt caacaaatca agaaatacgt gatagataca tctgttatct
     2401 tgaatgatgc gcttgataat ggcaaacgtg tgctttttga aggtgcacaa ggtgttatgc
     2461 tagatatcga ccaaggtact tatccatttg ttacgtcatc aaaccctgta gctggtggtg
     2521 tgacaattgg ttctggtgtc ggtccaagca agattgacaa ggttgtaggt gtatgtaaag
     2581 cttatacgag tcgtgtagga gatggtcctt tcccaactga gttgtttgat gaagtgggag
     2641 aacgtatccg tgaagtgggt catgaatatg gtacaacaac tggtcgtcca cgtcgtgtag
     2701 gttggtttga ctcagttgtg atgcgtcata gccgtcgtgt ttctggtatt actaaccttt
     2761 ctttgaactc tattgatgtt ttgagcggtt tggatactgt gaaaatctgt gtggcctatg
     2821 atcttgacgg tcaacgtatt gactactatc cagctagtct tgagcaattg aaacgttgca
     2881 agcctatcta tgaagagttg ccaggttggt cagaagatat taccggagtt cgcaatttgg
     2941 aagatcttcc tgagaatgcg cgtaactatg ttcgtcgtgt gagtgaattg gttggcgttc
     3001 gtatttctac tttctcagta ggtcctggtc gtgaacaaac aaatatttta gaaagtgttt
     3061 ggtcctaaga gatttttaag atttgtttaa gataggtcgg gtatactata gacagttata
     3121 agaagacctc ctaacttgtt gtaacaaata tcctaaactt ttctttttca taataatctc
     3181 ccttaactcc acccaatcag gtggagtttt ttagctctat ttcaggcttt tggggactat
     3241 tctaaaaata atttttcgat atttttcgga ttttggtcgg ggaattggcg gggacttttt
     3301 tagcgaatat gactaagaaa taggtctgtt gtcgcttcag caagttcgtc ctctacttga
     3361 ttgtaacgat ccgtcatata aacctttgta tgccccagcg cctggcttaa ttgttcaagc
     3421 ggaacccctg caataatgct ttgagtcgtg aagaagtggc gcatcatgtg aggtgttaca
     3481 tgcaatcctg ttgcttcatt cactagattg aagtttctat ttagctgatt tggattgatg
     3541 agaccacctt tctcgttgat agttatataa tccttgtgct gttccttgat aattcctaac
     3601 tttcgcttaa tcttagaagc ttcagctatc agataataga tcaggtctgt tccgatatca
     3661 tcaaggcaga catatcgctc tgaatccttc gttttaagcc ctcctttccc ttttaaggtc
     3721 tggttgcttc gactgtctct aagatgcagt atagcccgtc cgctgtcgtt ctgagtgatg
     3781 tccattggac gcaatccaaa gacttctcct cttctcaatc caaaaattgt cagataggtc
     3841 agagcgtaga attgttttgg cataatctct tctgcctttg ctatccaagt cttgaactct
     3901 ttgagagtca ctttcttgtt tgcagcaggg atatcactct ggccgatgaa aacacctttc
     3961 aagcgatttg agagcagatt tccatttttg acggcatcat tcagcaatgc catgaagctg
     4021 gaattgaggg tttgaacagt gtatctggta tggttctgca acttttcagc gataaatagt
     4081 tcatactcat ttctatccaa atttttaagc aggatagaac caaactttgc cttgatatgg
     4141 ttcttataga gattgtcatt gaggtagtag gaagtgtcat tccagcgccc tgttgacaat
     4201 ctcttttcag aatagatatc ccaatattga tcaagcgtta gattcgtatt gatacctaat
     4261 tcttgttctt ggatttgttg ctcaagctct accaaggctg cacgagcttg agggagagtt
     4321 gtgaaaccac ttttactttt ttctcttttt ttacctcgga agaaaaaaga acgtctgaca
     4381 tagtaacgct tgcctttagc agtctcatag taatagatat ttgggtattt tgttttatta
     4441 tatttcattg tattctcctt gtttatcggc ttctggacaa ggtctaaaca ttgagaatat
     4501 tgacatcacc cctttcatgg tgtaaaatag ggtatagaaa agaggccttt ttaatggctg
     4561 attttttata agggtaagct tcacaatcaa actttggcga gggcgattgt ggggcttttt
     4621 ttttattttc tgaatagttt gtatagttta tacaaactcc aagctgtcaa agggactgca
     4681 aggaatggag cgattggaat accaacaact ccaaaaaaga ctaagaaaag atacagtgct
     4741 gaaaatatga ttttattggc aggaagtttt ttcttaggag atgtttctga aagattaatc
     4801 tcgtttacta tatcagcgac actgtcacta acaatatttt gttcaatatg ttcagtttca
     4861 gttgttttag tttcaatagc ttcagtttcc gtaacttctt tattggaaat gttatcatca
     4921 attatctcag atgattcgct ctgaattact tctttttgtg aagaatcaac aatggtaagg
     4981 taaatttcaa aaccaacatc caaatcatta tttgtgacaa ctttttcttc atactcgtcc
     5041 cattctttat atgggccacc ttttatctct ccctctatta caaagttata ttttttatta
     5101 tcaaaatatt ttcgtattgt tttagcaatg gttgcaggaa catatcctac atgattatca
     5161 aatatcaaaa cttttatagc attaggatca tatctattat ctacttctgg aacgagctca
     5221 atattgaaaa agtctaaatc ttgatatttg aaaactttca gaccatattc ttcaagttct
     5281 tctctaagtt ccttagttga taaattgcta tagtactttg catattctgg gattccgtta
     5341 tcttcagcaa tcatattgca agcttctttt actgcttttt tatattttgt cactccagcg
     5401 actctgaata atattttttc aacagtcttt tgcatatatt tcccctctat ataaatatct
     5461 tcaatgcaat ttttaattta ctaatgccaa gtactcttcc ttgaccatga cttcattagt
     5521 catagttttt agattgtagt aagacatgaa tttgaggtaa tcaaactctg tggggtcgtc
     5581 taagctttct agtgcgtctt tcacgagatg atggatcata ttcctatcag cttcgttttc
     5641 acagcgtagg cgagcgtttt ggtactctga gcgtgtatgg tctttgtgtc cgagttagtg
     5701 tagggcgact tggatttgtt gttcaggagc taagttgtgg tcaatagcga gtacgtttgt
     5761 gtctggattg tagaaaccgc tactgtgcca gtttgaaccg tcgaagagac aaagctctac
     5821 ttgatattct tcgcagagtt tagcgagtat catagttctc cttcgttatt tataaacatc
     5881 tctgcggtgg gcgatttcca cggctaggac gactagttta tcgtcttgga tatcacagat
     5941 gatgcggtaa ttctctactc tgtatcgcca gtaacctgca aggttggctt ttagtgcttt
     6001 tccgtgttgt cgtggattgg tcgtgttttc aatgttttta gcaagccagg ataggatttg
     6061 ttttctggtt ggggtatcta gttttttaag ttgcttgaga gcttttttat caatatctag
     6121 ccgatacatt aagcaatatc ctctcgagat agtcctagtt catccaagac ctcatccatg
     6181 gtataagtag ctgggtcggc taaatactcc atataggctt ggtcggctgc tcgtgcgtct
     6241 tcgatatctt ccatgagtac catgaagtcg tcaaaatcca tggttgttgt gtcgataccg
     6301 tgtttggtta ggtagtccgt gatgtaggag tttttttctg tgaaattgat cgtgatagtc
     6361 attagcgttc tcctttgctt ttgaagtggg cggatagaac ggatgtgatg aagtcgatat
     6421 catcttcatt tagtggtttt ccgtcaaata acatggtgtt ggctgctgct ttgcgtaagt
     6481 ctatgatttg tccatttact tgagcaaatt catcacttcc agcgatagca ggattatctg
     6541 tccgtccgag taggtagtca gcacttacat taaaataatc agctatttct tttaaaactt
     6601 ttgaactagg attacttctt tttaatcgat ataaagtatt agttccataa ccaagttttt
     6661 cttctaaaat atttatagaa atcccctgtt tatcagctaa ttcttttatt ttatcgaatg
     6721 ctacaaacat taatttttca acctttctaa gcaaacgaaa aataatttta aaatatttgt
     6781 agaaaatagt tgacttattt agtcaaatgt tttaaaataa tattcgtaag ctaaagagtt
     6841 agcgaactag acaactaaaa aataaagcct tacaaaactg attggcgtcc gtttactgta
     6901 ggtaaaactt acttttagta ggtcttttct ctatgttttt attttaaaac atttgactag
     6961 agttgtcaag aagttcgcta actttttaga taatttttta aaaggaggtc agggatgaac
     7021 gaagaagacc tgaaagaatt attggaactc ttagcgacag attatgggcg agggtatcta
     7081 gatggagtag ttgggggact ttcaatgctt ttgaaaattt caaaagaagc agagaaatat
     7141 agaaaggaaa aatatgagta aagcaaaatt attagtcaca taaagtaggt aaacgaggta
     7201 ggaaatgata gaaacactgg aaataaaaat aaacaaaaag acatacttca tatctgcaag
     7261 ggcagatgtt ccagtcaggt ataaagttat gtttggcaga aatctcttcg atgacttttc
     7321 gaaaataaaa aacaataaag atgaaactct atcactttgt ctattatttt gtatgacaga
     7381 caaatcgtca gaagaattct gtaaattttt tattgaaaat aattcatata taacaagtag
     7441 acatcactat gaggcaataa gattatttga aaaacatttt atctttaagc ccgtaacata
     7501 ttcactagag gacatagttc aaatcctaac aatatatcta gaaaatacta aaacacagat
     7561 tggaggaaaa aatgagtaaa gaactaaaaa taattaaggc taaaattaaa actcgtttga
     7621 ttgagttgga tatgactcaa gtcgaattgg caaaacaagt atctgtagca tcatcagtta
     7681 tttcagagtt gctgaagtat ggaaaaggaa gtgattatgt gaaagaaaaa gtcgtagata
     7741 ttttgggtat tgaaaaccct tgggaaaata gttagagcat gaggaaatag tatgaacaac
     7801 gcagcgcaaa aagtaacacg gattgacaaa gatgcctggg agattgctac ggagctggcg
     7861 aacgagtacg gcgtatctat ttgtcacatc atcagcgaga gcgtccgcta ctgtgcagag
     7921 aatgccgaat ttaaggagat ggacgttgtc gttaaacgat tggtagtcgg cagtaaggtg
     7981 ctggagtagg agggtggaga tgaatgaact agtatggttt tactttgttg tcataatcaa
     8041 tcttatcatt ggttttgcta catactacgc tagcaaaaga gatagagaaa agcgcatcaa
     8101 cgggtttaaa aaaatacaag atgatgagct tgaaagagtt agaaataaat ttaatttatg
     8161 attttttaga agtcttttga ataaatcttt tatttaagtt ttgtttgcta ttgcttgctt
     8221 tattagctat ttttaaagct ttgtcaaaat caacctcgcc tgtaaaaact ttgtaggtaa
     8281 gatcattcat cttcatagac ttgtcggttt cagtatcaag ctgagatacc ttctcaagtt
     8341 cttgcaaccg taattcatga gcttgtttga ttttttcaag ttcaaaggca tgttgctgtt
     8401 ttagagtatc tatctgatga tgaaattctc tttcgagttt ttcaacagta tgtgaatgtt
     8461 ctttggcttg tttttcaatc tcagctttat tgttagcttt tgatgcgaca tatgaccata
     8521 accctgatat tattgcaaga ataatactaa tcacaggttg aataagagct tgatattcca
     8581 taagatttct ccaatcgttt tattttaatt ataccaaatt tagaaaggaa ctttatgaac
     8641 gaaattttta attttcacgg gcaggaagtc cgtactttga tcattgatga cgaaccttgg
     8701 ttcgttggga aagatgttgc agacatccta ggatatagca aggctagaaa tgcgattgct
     8761 cttcatgttg atgaagatga cgccctaaaa cagggcctca cagataattt aggaagggtt
     8821 caagaaacta tcatcatcaa cgaatctggc ctctactctc ttatcttatc cagcaagttg
     8881 cctcaggcta aagagtttaa gcgctgggtg acatcagagg ttttgccagc tattcgcaag
     8941 cagggcggtt tcattcgcga ggacttggac gaggatgcct ttatcgctct gtttactggc
     9001 cagaagaaat tacgtgagca acaggcgacc atgctggaag atattgacta tctcaagagt
     9061 gagcaaccga ttcacccaag ctatgctaaa tcgctcctga agaagcgtaa ggctcgggtc
     9121 gtggtttgct taggtggcat tgatagtccg gcttatgcgg ataagacttt cgctcagtca
     9181 gtctttagac aagctgagat tgactttaaa gaccacttca acattaatcg ctatgacttg
     9241 ctaccgaaaa aattcgcaga tgcagccttg gcctattgga tgacttggga gccaagcacc
     9301 aataccaaga tgaaaatcat gaaattgaac tcatttgacg aagggtagga ggggaagaag
     9361 atggacaatg ttctactttc actgtctgaa tggattaaat ccattatcaa ggacacaatc
     9421 acaaggctag tcgaaataga aaaagatagt gaccactatc cagagctgat ggatgtgaac
     9481 actacctgtg attttctagg aattaagtat gccacctttt cagataatta tcgttactta
     9541 aagggatttc caaaggaatt acctggtaag aaatggtcaa aaagagccat caaagaatgg
     9601 ctctctaatc aaatataata actttactaa aaggcttctg gacaaggtct tagcaaaatt
     9661 atttgactat attatagcac aaaaagagga taaggagata aaaatgtttg aaccaccgat
     9721 tttagaccag ctgatggggg ttggagcctt actgcttgga tttgcagggg cttgccgtca
     9781 tatcaaattg caggaacaac gcaaggaaga agaaagacga gaagagcaag aatttgcgtc
     9841 tatgattatc caagtgcgta atcatgcata tgaacgtggt agagaggaca aatggcaaga
     9901 aattcgcaag aatattcgca gagagttcaa aggattcaca tatgacaacg aaccgcctgt
     9961 aggcttgcgt cctgagccgt tagctttgcc agaacctaaa cagtctgcaa tcagattttt
    10021 gtaatgagga ggtcaggaaa tgcaagaatt gattgaatcg ctggataacc tgattatgat
    10081 tgttaaagaa ctggaaggaa gggaatcaac ttcaagacat tttattacga tatgggaaaa
    10141 cgattataaa aatctattac gagtcaaaga atacctaacc gactatgaaa aactagcaaa
    10201 ggactatcgt tatatgaccc ttaaaaataa gctgctaaag attgaaaaaa tggagctgga
    10261 aggcaggtac atctatgaag atatgcggat gaagtatcgt gccaatcgca ggaagtgggg
    10321 tgctcggtat gtctgaaatc aagtggataa aaatcaaaac ggatattttt gacgatgaaa
    10381 agatgtgtct aattgatgcc tcgcctgatc gtgatgcaat tattgtaatc tggatcaaac
    10441 ttataacact agcaggcaaa ttgaatacaa aaggcgtact aaccatttct aaaaacattg
    10501 tatacaccga tgaaatgctt gcacaaacgt tccaccgtcc gttgaataca gttcgtatgg
    10561 ctcttgaagt ttttgaaaag tttggaatgg ttgaaaaaat cgatggagtg ataatgttac
    10621 ccaattggga gaaacatcag aacattgacg gcatggaaaa aataaaagag caaaatcgaa
    10681 atagagcagc acgtcaccga caaaaacaga aattacttgc acagaacaac gaaagtaacg
    10741 ttactgataa cgttatggat aacgttacag taacgcatgg taacgcacta gataaagaat
    10801 tagataaaga tatagagata aataataata aggtgatgat tagttccagc ctttctgaaa
    10861 atttgaaaaa tagcggaatc catctaactg ataagtcaca tcaacagtta cttgattatg
    10921 tgggacttga tggaatgagt ttcgatatgt tgaaccgtgc agtcgagaaa acttccggat
    10981 cacacaaacc tagtttcaat tacctaatag ccattcttga aagttggaaa aagaaaggct
    11041 tcacatcgat tgagcaggtg gatgaggacg accgtaaata taaagagggt aagaagtcaa
    11101 gacaacaaaa cgataaaaca tcggaacagg aggtaaggga cgaatgggga ttttagaact
    11161 aattgagcag ttcgagattg actattatcc gttaagctac gagaagaaaa ctcttttagc
    11221 agaccaacca attcatccag tggttgcctg cttgtctgaa atggctagct ggcatgaatg
    11281 cggaggtcgg ctagtatggt agacaatgtg tttgaggaaa tcgccttatc ttatcgtagg
    11341 aatacagaac aacaagaaga gttctgcgaa aagcataaca tccctttgat aaagatattg
    11401 aggaccgaga gtgttgtatg tcgcatgtgt gaatctgagc ggattcatga agaaaatcag
    11461 gaaagagtga atgaactggc taatgctgag aatgagcgag agaggaaata ctatcttgaa
    11521 aagttctctc tttatgatga aattttgaaa aatgctactt tggacaattt tgaaacacca
    11581 accgaaaaag aagcggaaaa gctagctttt gcaaagagga tttgtcgtga gtggtctgag
    11641 ggtgctagga acaacattgt acttcaggga gaagctggaa ctggtaagag tcatttggct
    11701 tttgctatgg ttaaggctct atctgagtac acgaaagaga ttgctatttt tattaacgta
    11761 actgacttgc tgatgaagat taaagctgat tttagtcagg aagagtttct ggtcaataaa
    11821 attgctagtg ctaagttctt ggttttggat gatttaggaa tggaaaaaga tagcgaatgg
    11881 tcatttacta ttctctacaa tatcttgaat aagcgttcaa acacaatcat taccacaaat
    11941 ttgatttctg ccgatattca aaaaagatat ggcagacctt tcatgtccag actaatgaag
    12001 ggtgtagata aagaccattt gatggttttc aatgatttga caaacaagcg aaagcaatat
    12061 ttttagaata ggggtggctg atgtttattt taaagcatgg gacaagagag gataagccgt
    12121 ttctaaggtc tgcaattatc agtgtgactg gcttggatat ttcgtgttct gaggagaaga
    12181 aagccatgcg gtttatttct cgggcggcag ccttacaggt tagcaaggca ttgagaggtt
    12241 cctttgggaa cttctaccct gtcgaggtgg agtgatgtta gagctttatt tcgtctacaa
    12301 cgggcactgt aagtttttcc ttgggaggtt tgacaatgtc gatgatctca ttgagcagat
    12361 ggaagaccat cagtgggctt tctcagctat cactcatcca aggtttcaga agcacattgg
    12421 tcagcggacg acacgatttg actacggttc taaggattgt tactatttag cgactttttc
    12481 aggaggagaa aaaaatgatt gaacttatta aagaatttgg aatggctatt ctgtggttat
    12541 ttcttggcta tttagtcggg gaacgtgcag caagaaagga aaagaaagat gatcaataac
    12601 gttacatttt tagtgggagg taagaaacat ggttggagta acctatcagg aaattcatct
    12661 ctttgttgaa tttttgaaag agcagtacgg gcaaggtcgt ccagactata ttgaagccct
    12721 gaacgactta gacggtctgg tggaagtctc ctacagagaa gctattgaaa gatttttaga
    12781 agatgaagta cgataaacag gctgagattg acggactgaa acgcacgatc gagcaaaacg
    12841 aagagaagat aatcgagtat tcgaagccgt gcgatgcacg caagagacgg attagagcgc
    12901 tggagcgcga tttgttgagg aaaaagaata aagaattaag acggaaagcg gaggagttgg
    12961 aatatgatgg aagagttaaa gcaaaaagtt aatgaagtat acaactggac ggtagaagac
    13021 gggaagccgc aacctcccaa gcaagattta ccacaagcgg tgaaagaccg ggcggactat
    13081 ttttgggaaa tggcagaaga tggtatgacg tttatgggag cgatggaatg catcttcgct
    13141 gatgaaaagc ctacagacta tgatttggga gctactaagg gttggttgcc aaaatctaag
    13201 gagtttgatg attgggttgg ctattcgcca agcatgtctc agttagttat tgcagtttat
    13261 ttgatttaca gaggaagcga agatgaaact taatgaattg attaagaaat ataaaaaact
    13321 tgagggtgta tggaatgctg aaggagcaga actagttcgt caaatttttc tgcaagactt
    13381 ggaacaacta gataaaccgc aaccagtcaa agttccgcag tgtgtggcgg aatatataga
    13441 atttaaaaag aaaaacaatt ttcatgttta cggtcttgct tggcttaacg gctacgaggt
    13501 cgaaaaagag aagcggtatt ttgttaagat taaagggaat attaaagaaa atatgttggt
    13561 ttatggagaa cttttgaaaa ggtatttctt tacaaaaagc tttagtttag acgatgttat
    13621 atattcccac actcgtaaag aactagaagc cgcaaacttc ggctgggtgt ttgattgccc
    13681 aggtattgag attgaggagg tggaataatg ggagatatac gaatactaga cgcttgttgt
    13741 ggcagtcgta tgttttggtt tgataaaaat gagagtcata caactttcat ggacatcaga
    13801 caagaaaaat ttgaaataca tggaaaaagg taaacgtaaa ccctgacgtt gtcggagatt
    13861 ttcgtgatat gccattcgat ggtgaaacat ttaatctagt agtatttgat ccgccacatt
    13921 tgaaatgggc aggtcaaaac tcaattatgc gatcacaata tggccagctg gataaagtta
    13981 cctggtcgga agatttagcc aagggttttg aagaatgtat gagagttcta aaagttggag
    14041 gtactctagt ttttaaatgg tctgattgtc aaatcaacgt taaagaagtt cttaaatctg
    14101 taccttttaa accattgttt ggacaacaaa gaggtactac gcattggatg acgtttatga
    14161 aatttgagaa ggtcacagag agaaaggacg gcacgtttgt aaaagaggag gatttggcat
    14221 gataccgaaa tttagagtgt ggcatcatga attaggtaga ctgatgtcag tcaaatgtat
    14281 gttttttcag gatagcgaga ttgaagaatt tgagttaaac gatgctttaa tgaatgatta
    14341 cattacagct tatcctgatg aaatcgaact catgcaatca acaggactca aagacaagaa
    14401 cggcaaggag gtattcatcg gtgacatcgt taaatgtaca agaggatgtc tccatgaagt
    14461 atatttagaa aaagaatacg gtggtacatt cataggtgga atgcctgctg tatacctaaa
    14521 aggacttgga gatggatatg cgtggacgga atatgaggaa atcatcggca acatctacga
    14581 aaatccagag cttttggagg ataaataatg aacccagaaa taattgacaa tataaacaaa
    14641 ccaagccact accaaggtgc aaacggtctt gaggctatcg atgttgtgca taacttcgtt
    14701 gggagccttt ccggagcgtc tgctttcttt tggggcaacg caatcaagta tatgttacgg
    14761 tttcaaaaga aaaatggtct ggaagacctg aagaaagcta gaaagaatct tgactggctg
    14821 attgaggaga tggagcatga gtgaatacgc attgtatgaa ggcgacacct ttattaccat
    14881 ggggacgctt gcggaaatca gcaaagaaac aggaattgct gaacggtgca agtatttcag
    14941 agtttgccat cgaagatatc tgtacgtttt ttgggattga gatccaagaa aggaaataaa
    15001 agtcaatgaa caaaagaatt aagaagaaga tagctaaacg gcagatacaa gaaaagcaag
    15061 aagaattata caaacaacta cggaaattaa gttctgaaga aattgaagct ataactaaaa
    15121 tgattaatca ggcagtttct aatattcgca aggctttctc tcagatattt gataacttgt
    15181 ttacattttt gaaaaacttg gaggtggaaa ttgaaaaaat tgagcgacga agaactcaaa
    15241 acgttagaca gagaactttt caaatttcaa aacattcaac gcacaataga cttaagaagg
    15301 ctagaattag aaaccagaaa cccagatgct caaagtgggc caactgtagg aataagcaaa
    15361 cctaccgaaa ctatcgcaat cagaatcgca gatgatccga ctttaaaatt tcttgaagga
    15421 tttaaaggga ttattaacaa actcttaagc aatctagtcg aggaggacaa agaaattttc
    15481 aatctacgct ggagataccc tcaactgaga tgggaagaaa tagcagaaca gaaattcatg
    15541 agcaaagcta caatctatcg acgtagaagg attatcttag aacagtacgc tataatgaaa
    15601 ggtgagttgt aaataagatt gagacaaaag acatcttgaa gtctcacaaa aaaagggcta
    15661 ttatgatagc atgaacttct gaaaacaaaa acacaaatca catgttggag ttatcctatt
    15721 tttacagaaa agttgtttaa cagaggaaca tcatgagtca gcaaccagct ggctttttgt
    15781 tttgtagaaa ggaggcagtt atggaatttg tatcaccgat aaaagacaat gataatattc
    15841 aagctatgaa agattatctc agagaatgga atgagatgta ttatatgcta ttcatcacag
    15901 gcctgaatac tggcttacga gtcggagata tacttacctt gaaagttaaa gatgttcaag
    15961 gttggcacat caaactgaga gaacggaaga ctggcaagca gataacaaga cggatgacaa
    16021 aagaactcaa gaaagaaatg aggagatatg ttgaaggcaa accatttcat catttcttat
    16081 tcaagagtag gcaaggtcag aataaagcga tcactcgtga gcgagcctat caaatcatac
    16141 atgaagcagc tgaagaactt ggcattgata atgttggcac acatacaatg cgcaagacat
    16201 tcggctataa atattacaac aagacaaagg acgtaggaac attacagaaa atgttcaatc
    16261 actcatcacc tgcaatcacc ctgagataca tagggataga gcaagcagag cttgatgacg
    16321 cactacggaa ctttgtcatt taatttttta gatattactt tcacataatg agttaagcat
    16381 aaactgaaaa aatgaaagtc ttcaaaacct atgattagta agggtttgag atttagagtg
    16441 agtttaacaa aatataagat atgtgaaagt gagggataaa attggtatag ttacaagagg
    16501 tgaaaaatgg taaaagaata ccgtgatgat tttcttggag aaaaggcctt cgagaaatta
    16561 aataaagata ttgatgccaa tcctgaagtt ggctttgaaa ttgttggata tactcaaaca
    16621 gcatttgtaa atggaatgca tataccgtta acagccatac tagtaaaatg gaataatttt
    16681 tttaaagaat cagaatgaga caaaagacat cttgaagtct cacaaaaaaa ggtttattat
    16741 ggtagcatag atttcttgta tgaggagggg ataggtcaaa ggcctatccc ttttagcatt
    16801 gagaaaggag gtttgagatg tataacaaac ctatcagacc atccttgaaa tctaagaagt
    16861 gggagaagtt ccgtgatagg ataatgcgta agcatgatta tctttgccaa gaaagtttgc
    16921 gttacggaat ttctgttcaa gcagaaatgg tacatcatat ctttcctgtg tctgaatatc
    16981 ctgagcttga atttgttgaa tggaattgct tgccattgac gaataagaaa cataatacgt
    17041 ttcatgatag agtgaacgat agagtaatca accaaggatt gtattggcag aaaaaaagaa
    17101 aaaaagaatt tttaaatttt ttcaaaaatg aaaaatgaaa atttttaatc cccccctctt
    17161 tttgaaaaat cattttggcc agtagggtac tggtgaaggg aactttttcc aagtcggggg
    17221 ccttcaaaca aaaagggggt aaaaactaag cgattttgac gaaaggaggt agtttttggc
    17281 taaaccaatt acagcaaagt cgattaagtc aaaagtggtc aagcagatga aagacttggg
    17341 aacttatcgt aaagagttcg aaatgatcat tgacattttt gcaggtatgt tataccagta
    17401 tcagaaactt gctcaagatt atgctgatat gggttatcca gtaacagaca cctacgtcaa
    17461 taaggctggt gctgaaaatg agcgcaaagt tccaatcttg acagcgatgg aaattttgag
    17521 gaaagatata ctcagctact ctaatcagtt gatgatgaat cctaagtcgc tcggtgaggt
    17581 agtagaacaa gagggtgagt cagttcttac tgaggtactg aagttcaaga acgaaatcaa
    17641 gaagaagcga gtgactggca atgggtaatc ttgataaagc taaaaaatac gctcaacacg
    17701 tcttaactca ccgagaagaa cattgcgaag aaaacatcct tgctgctgaa cgttttttcc
    17761 gtgatttaga aaatccaacc tttgagatgg atgaggatat ggtggatttt gttattcact
    17821 ttatcgagaa cgtgatagtt catcagcagg gcgatgatat gtttgcggta tctatccgta
    17881 acaagccatt gcttttgcaa ccgtggcaac atttcgttgt agttaatctg tttggttttt
    17941 actacaaggg tacgaatgag cgcaggttca aagaagcgct tatcatgctt gctcggaaga
    18001 atgggaagac ctcgtttact gctgcaatcg cacttgctta tcagatatta gatacagata
    18061 gcggttccaa atgctatatc gttgctaact cagtcaagca agcgatggaa gcttttggtt
    18121 ttttaagatt caacgttgaa cgctggaacg ataagaacat tcgtatcaag gataataacc
    18181 aagaacactc tatcaccgcc aattttggtg atgaaggttc tttctttatc caggctttag
    18241 cgaatgatga gagccgtctg gactctttga acggaaatgt tatcatcttg gacgaagctc
    18301 acacaatgag gaacagtaag aaacatggtc ttatgaaaaa aacaatgtca gcatacagaa
    18361 acagtatgct ttttgttatc tcaacggctg gggatattcc taccgggttc cttgctaacc
    18421 gtctgaaata ctgtcaaaag gtgctcaagc aattagtcac tgatgattca tttttcatct
    18481 tcatctgcaa ggctaatcaa tctgctgatg gggacgtggt gaactatctg gacgagaata
    18541 tcctcaagat ggctaatccg tcatggggtg tcacggtttc gctcaaggct ctcaaggaag
    18601 aagcagagca ggctatgaat gatcctcaga caagaaatga gtttttcaat aagaccttga
    18661 atatcttcac taactctatg aacgcttatt ttaatcctga tgagtttatt gcgtcggata
    18721 gttgctacga ttggagttta gaagagctgg cacgtttgcc tattcgttgg tatggtggtg
    18781 cggacttgtc aagattgcac gacttaacag ctgctgctct ctatggtgtc tatcatgacg
    18841 gtgagaaaga cgttgatatc tgtatcacac atgctttctt ccctcggatt aatgctcaga
    18901 aaaaagctaa tgatgacggg attccactct ttgggtggca gtctgacggt tggttgacga
    18961 tgagcaacac tccgaccgtc ctctatgatg atatcgtcaa atggttcatc aagatgaggg
    19021 agaaagggtt caagattgct gctgtcggaa tggataggaa gtttggccgt gagttcttga
    19081 cgaagatgaa acaagctcgg ttcaagatga ttgaccaacc tcagcttttt tatctgaaat
    19141 cagagggatt cagacggatt gagtttaaag ttaagaataa agaattttac tatcttcatt
    19201 ctgatgctta cgaatactgt gtgagcaatg ttagagcaat tgaaaaggtg gacgatgctg
    19261 tgcaatatga gaaattagat ggagacggtg ggactgcaag gattgacttg tttgatgcca
    19321 gcgtctttgc ttgtatacag gctcttgcta atcttggcaa gggtggtgat gtgatgagat
    19381 tctttgatta ggtgaattat gaatgaaata gtattatcag aacatgaaat taacttgctg
    19441 atcaacaaag ggcgagttaa agtaatttta aacggggaag tagtaactat tcgtcaaaga
    19501 catatgaaaa atttgatggc tgaaacagta aaatgggaaa aacaggtaat tgatgtcagt
    19561 cagaatatcg taagaaataa acactttgat tcactttttc aaaatacttt tcgttagaaa
    19621 ggaggtgagg aaacatgggt atttttgaaa agttttggaa acgaaacaag ccaagtaagt
    19681 caatcaacat gctgagtcat tcagatttag ggttgtcaaa cctgatggac tcgtatgtac
    19741 ctttggccag aaatccagat gtggtgacag cggttaataa gattgctgat ttggtctcta
    19801 atatgaccat ccacttgatg gagaatacag ataaaggtga tatcagaatc cgtgatgggc
    19861 ttgctagaaa gattgatatc aatccgtgta aacacatgac aaggaagtca tggattttca
    19921 agattgtgcg cgatttgctt ttatatggcg atgggaactc tgtcctacat gtggaatatg
    19981 aacctgttac ggattatatt tctaatctaa gaccatttcc gatgagagag gtttcattcc
    20041 aaacagataa ggattcctat gtaatctcat ttaggggtga agaatattcc cctgatgaag
    20101 tagtccactt cgtcatcaat ccagatccag atattccata cattggtact ggttttaggg
    20161 tgacgttgac agatgtggtt caaagtttga acatggctac caagactaaa aaaagcttta
    20221 tgaacgggaa gaatattcct agtcttatcg ttaaagtaga ctcgtctagt gctgaactag
    20281 attcggagca agggcgtgag cgtatcgctg agaagtattt gagtactagc agggttggcg
    20341 ctccatggat tgttccagag gcattgctgg acattcagca ggtaaaaccg cttagtctaa
    20401 cggacatcgc tttaaacgag tctgtggaat tggataaaag aacagttgca ggtctattag
    20461 gagtacctgc ttttattttg ggtgtaggag agttcaacaa gacagagtat aacaactttg
    20521 taaatacgac tgtcatgagt attgctacca ctattactca aacactaacc agggacttac
    20581 ttttgtctag caatcgttac ttcaagctaa atcctcgttc actcttctct tacaacatta
    20641 cggagttgtc tgctgttgct caacaaatgg caaacagtgc tgcaatgcgt cgtaatgagt
    20701 ggagggattg gctagggatg gctcctgatc ctgagatgga agagttgatt gttcttgaaa
    20761 actttctccc tcaggagaaa ctaggagatc aaaataaact gaagggaggt gaggaagaga
    20821 atgcaaaagc gaaatagcta tcgtgccact caatttcaaa cgagagaaga agaatctggt
    20881 gatttgattt tgagtggcta ctttatcaag tttgacgagg agacggaatt gtggccaggc
    20941 tactgtgaag ttatcaagcg tgctggtgtt gagaaagctg tcacagacgc tgatatcaga
    21001 gctttattta accatgatga tagccttgtt ctcggtcgaa caggtaacgg aactctgaca
    21061 ctgggtgttg atgatgttgg tctttttgga gatatcatca ttaacaagga tgatcctcaa
    21121 gctgttgggg cctatgcccg tgtcaagcgt ggagatgtta tagggtgtag ctttggcttt
    21181 atcccggtaa aaatcgaaac ggaagaacgt gaagatggtt catatttgga cactgtctta
    21241 gagctagaaa tctttgaagt gagtccatgt actttcccag cctatccaca aacggaaatt
    21301 gctgcacgac aaaaagactt cgaaagtcag aagcgtgcta atcgtgaagc gctagacaag
    21361 cgcaagaaag aaattaagga gaaatttaat ctatgaacaa attattgatt ttgggcgctc
    21421 gtatgcgcaa caaagcagac aaagttgtag agcttgaaga atcaatcaaa gaattgaaca
    21481 agcgttctga acttgaagct aagaaattgg aacaagctgg aactgacgaa gaagtttcag
    21541 cagttgaaaa gaaccttgaa gacatccaaa aagaatcgga tgaaaaggaa gcagaaaaag
    21601 aacaacttga aaaagaaatc gaagatttga aaaatcaagt tgaagaacta aatcgtaaag
    21661 caccgactta cccaagtcaa gaaaaacgtg gaggacagaa attggaacga cgtgacgcaa
    21721 tcgctaaata cattcgtact ggtcaaactc gtgacattgt aggcttgaaa actactgatt
    21781 caggaagcgc agctttaatc cctactgaag ttttgaaacc tcattttgtt aataaaacac
    21841 gtaatccact tttggatctt gtggaacgtg tgaaagttaa tagtggatct ggtaaatatc
    21901 cagttatcaa gaaaacggat ggtgtaatgg tttcaataga tgaattgaaa tcaaatccag
    21961 aactcggaaa accagcaatc agcgagattg attattcaat caagacttac cgtggatatg
    22021 tccctgtgtc acaagaaatg attgacgacg cagactatga catcatgtcc attgttgaag
    22081 acgaagtgtt caatcaaggt gacaacactg aattgtcatt agttacagct gtcctcaaaa
    22141 cagctaccca agcagatgcg gctggatttg atggtattaa agatatctac aacaagaagc
    22201 ttaaatcaat ttataaagca agcatcgttg taactaagtc aatgtttgct gcgcttgaca
    22261 aagtgaagga caaagatggg cgctacatgc ttcaaactga tgtggcttca cctactggct
    22321 attcatttgg tgggaaaaca atctacaaag tagatgacac agtgtttgga aacgaaggag
    22381 atatgaaatt cttcatcgga gatgttactg agttcgtcaa agagtttgac cgttctcaag
    22441 tatccgttaa atgggtgaac aatgacattt acggacaatt gcttgggctt tttatccgtt
    22501 tggatattaa gaaagcagat gaagaagctg gattcttcgg aacatatact gatgttgtag
    22561 cttaaggagg tagcgtatga gctataaagt aatccgtcct ttcaaggact tggctgatcc
    22621 tgaaaatcat gactacgctg ttggcgatat ctttcctcgt gagggatatg agccaacaga
    22681 tagctttacc aatggccttt tgactggcgc taacactgct ggctctatct tccttgaggt
    22741 tttgggagat gatgaaccta agaaaccagc gcctgaaaca aaagaagtga aggaagagcc
    22801 cgcagttgag caggaagaaa cagttgagga aactgctgaa gagtctgctg aggaagttga
    22861 ggaatagaca tggaccaagg tcagctttta gagttgctga agcttaagtt gggtatttca
    22921 accgacttga gagacaagcc gttaaaaaaa atcatttcaa gtgtcatcac tgaattgacc
    22981 gataatctcg gtatcgagct tgttggtgag cgtgctgacc atgaaatgtt tatcgttgac
    23041 tatgccgctt atcgttatga gggtggggtg gatatgccac gtcaccttca gtggcgactg
    23101 cataatttac agatagcatc aaagaaagag gtcaagaatg tggaatcatg aaatcacact
    23161 gatctccaag aaagtaacag gtaaggataa gttactacaa ccaatctctg aagatgttga
    23221 agttactctc ttatgtcgca aaaagagggt cactcgctct gaattttatc aggcgaatca
    23281 ggtagggctt aaaccgagct tggtcgttga gattcgaaat tttgagtatg agaatcaaga
    23341 gcttgcgaag ttcgaaggca agcaatatca tatcttgaaa acctatccta ttgattctga
    23401 aattttagag ttgactttgt cagaggtgtt gaaatgagta atgaccttgc tgatttgata
    23461 gcgaaagagc ttgcagctta ctctgatgag gttactgaag aagtggataa gattgcagag
    23521 caagtgactg atgagactgt ggatgagttg aaagagacaa gtccgaaacg gtacggaaag
    23581 tatcgtagaa gttggaaaaa gaagaagttg gccaatggct cttttgttgt gttcaacgca
    23641 gttgcaagtc ttactcacat acttgaaaac gggcaccttt caagaaatgg tggtcgtgtc
    23701 gctggtatcg tccacatcaa gccagctgaa gaaaaagcaa ttcagaactt tgagaagcga
    23761 atcaaggaga ttgggaaatg aagctatcag actttgctgc tattttggaa caggcaaact
    23821 tgcctgtcac ttatcgagcg tttaaaattg gaaacgctcc tgacctacct tatctggtct
    23881 attatgaatc aagtccagtc atcaattcag ctgacaacac ggttaatcat cagattaaga
    23941 gcgtgacagt tgagctggct tttgagagta aggatgaaga tttggaagaa cgtctggaag
    24001 agctgtgggc aaaccacaag ctcttttttg aagttcaaga agaaacattt atcgagactg
    24061 aaagactcta tgtcaagtct tacacagtct atctatacta aggaggaatg acatgactca
    24121 agaaaataaa gtaacctttg gcctagaaaa tgtacatatc gcacctatca agacacttgc
    24181 agcagatgga gttatcactt acggcgatgt ttttcgtttt cctggagcaa tagagctgat
    24241 acttgatact aaaggggaaa caacccctat caaagcagac aacaaggatt accatttcat
    24301 gaattcaaac gaaggatatg agggtaaact taaaatccca cacatcattg atgaatttgc
    24361 gacaaaaatt cttggtgaaa tcaaggaccc tcaaactggt gttatgactg aaaaagcaga
    24421 tgcgagcttg acagagttcg caatgatgtt ccagtttgaa ggcgacaaaa acaagactcg
    24481 ctatgtgatg tactactgtt ttgccagtcg cccatctctt ggctcaaaaa ctaagaacgg
    24541 gacatcaacc aacgaacgtg aacttagttt caaagctagc ccgcgtccat tggatacagt
    24601 tgtcaagcgt tctatcacat cagctgatga caaggatgcg tatgacaact ggttcaagaa
    24661 agtgtatgaa cctactgcag ttgcagctta aggagaagat ctatgcgtaa aatcgttttg
    24721 gttggtgatc aggagtatga gttggggacc aacggctata ctcctattgc ttacaagcaa
    24781 caatttggaa aagattattt tcaagatttg ttctcgatgt tgaaaaatca atcattcatg
    24841 aatgaattga acaagttgga aaccgacaag gaattgacag cgactaatat tgatatttcg
    24901 atgttgtcag attttgacat gacctttttc aaccgtcttt tttggacctt tgctaaatct
    24961 gcaaatcctc acatcaagcc ttatgaacaa ttcttcatgg aaatggaaat cttcccgatt
    25021 caggaagttg gacctgtgct gatggaaatg ctaaatgcga gcatgacgac aaaaaagcac
    25081 cagatgagtc agaatcagct agcgaagaaa tcttcacagt agaatcctat ctatcttgct
    25141 gtaaagaaac tggtctttct attgatgatc taaagcacat ttcaatcgga atggctctgg
    25201 attatcagac ggattatgtg aatctacgga gcgaggataa gggtggcgaa cggaaagcca
    25261 cgcaagctga ttttgacagt ttttaaagaa aaatgagtgc tgagagagcg attctgagac
    25321 caagttcctt ggtctggctg cattatcagt ggtagaagtt ctctcagcgc ttttctattt
    25381 ttttgagaaa ggaggaaata tggcaggaaa tatcaaaggt atcaaaattg aaatcgatgg
    25441 cgacacgcaa cccttgcaga aggcgctgaa aaatgtcaat aaggccgcta ctgatgcaag
    25501 tcaggagttg agacagattg acaaggcctt gaaatttgat acagggaacg taacgctcct
    25561 gactcagaaa caagaggtct tacaaaagca agtttcgacg accaaggaga aactggaaac
    25621 cttgagacaa gctcagtctc aggtggaaca gcagttcaaa aatggtgata tcggtgctga
    25681 tcagtaccgt gcctttcaac gcgaagtcga agttactcaa aacgtcctaa aaggatatga
    25741 gggtaagctt gcaaatgtga atcaggcgct taatgagaat gggagtgcta ctcagaacaa
    25801 caagaaccaa ttaaaagagt tgcaaaatga gcagagtcaa cttgcttcag agatgagtaa
    25861 ggtgacaagt tcattcaaac tgcaagaaag cgctttgggt tcaaatgcta gtgaagccga
    25921 gagaaatgct cttgcccaga aaaagattgg tgcccagtct gagattgtaa gtaaacagat
    25981 ttcaaatcta gaacagcaat tggaaatcac taaaaaagaa tttggtgaga actccacaca
    26041 agccaacaag atggaatctg agctaaatca ggctaagact gcttttaatc atctcaatga
    26101 tgagatgaag ggaacaaagt ctgctgctga tagcactcaa gaaagtttaa gtgaaatctc
    26161 aagaaattta agagcagaac tacttcaaca gtttagtgag aagttgagtg ctatttcaga
    26221 aaagcttgtg gaagtaggaa aagaagcgtt agaagcagct gctcaaatgc aagctagtaa
    26281 tgctcaattt actaccgttt tcggagatat ggaaacccaa gcaagagaag cgttgaatgc
    26341 tattggtcag gaaatggata ttgtcccaga gcgtttacaa gggtcattta ctcagatggc
    26401 ttcatttgct aaaacttcag gactagacac tgcgcaagca ttggacctga cttcccgtgc
    26461 aactagggca gcggcggatg gcgcagcttt ttacgacaag tccatcgaga gcgtatcaga
    26521 aagcctacaa tctttcctga aaggaaactt tgctaacgat gccgctcttg gaatctctgc
    26581 gacagaaacg accaggaatg cagctgcaaa taaattgtac ggaaagtcat tcaaggactt
    26641 gagcgaagcg cagaagcaat tgaccttgct tcagatggtc gaagacggaa ataaactctc
    26701 aggagctctt ggacaggctg caagagaatc agacggccta gaaaacgtga tggggaatct
    26761 gaaacaagct gggaccaatg cattatctgc tattggtcaa cctcttctag aaatgatgat
    26821 tcctgttttt caaaccttgg caacgattgt gaaaggtgtg gccgagctgt tcaattcctt
    26881 gcctgatcca gtaaaagatt ttgttgttat tttaggaaca gttgtgactg ctgtaggggt
    26941 catagccccc atattcttaa ccttgcaagc ccttgctgag tttttaaaaa tatctattgg
    27001 agaaatgata attgccgcat tgccaattat tggaacagct attgcaattg ctgctgcagt
    27061 tgctgcaatt attgttattg taaaatatct ctgggaaact aacgaaggtt ttcgagatgc
    27121 ggtcacgacc gtttggaatg ctatactagc cgttatcaat acagttgttt cagaaatctc
    27181 tgatttcatc atgagtatat tcgggacggt tgttacttgg tggacggaga accaggaact
    27241 tatcaggaca agtgctgaga ctgtctggaa tgccatttat acggtcatca gtacaatact
    27301 ggatatactt ggccccttgc tccaagctgg ctgggataac attcaactga tcattacaac
    27361 aacttgggaa atcatcaaga tcgttgttga gactgcaatc aatgttgtcc ttggtgttat
    27421 ccaagcagtt atgcagatca ttactggtga ttggtcagga gcttgggaaa ctatcaaggg
    27481 agtgttttct actgtatggc aagctattca aagcattgtt cagactattt tctcagctat
    27541 ccagagttat atttcaaata ttctcaacgg catttcagga actgtatcaa atatctggaa
    27601 cagcatcaag gacactgtct caaatgtgtt aaatgctata tctagtactg tatcaagtgt
    27661 ttgggaaggt atcaagagta ccatttcaag tgctatcaat ggtgcaaggg atgctgtttc
    27721 ttcagctatt gaagccatca aaggattgtt taacttcaac atcagctggc cacatatccc
    27781 actacctcac ttttacgtga gtggttcggc caatccatta gattggttga gtcaaggtgt
    27841 tccaagtatt ggaatcgaat ggtatgccaa aggcggtatc atgacgaaac caactatctt
    27901 tggaatgaat ggtaataaca taatggttgg tggtgaagct gggaatgaag cagtattgcc
    27961 acttaacgac aaaacgcttg gagccatcgg tcgaggtatc gctcaaacta tgggtggaac
    28021 ttcaccaacc atcaacatta ctattactgg taacaccgtc agagaagaag ctgacatcag
    28081 tcggattgct gatgaggtgg ctcagcgtat tgctgacgaa ttacaacgta ggagacaatt
    28141 gagaggaggg tttgcatgat aaagcataat gagcttgtga ttgacggtgt gaggacatcg
    28201 tcttttccat ttaagatcat tgtccatgac tctccttcaa tcgctctagg agagagcaag
    28261 acagctctct tggagcatgg tggtgtcagt ggggcaatcg ttcagacaaa caagcatagg
    28321 gaactggtca agaaaactta tacgatttac ttggtcaaac ctactgaaga acagatgaac
    28381 caatttatga gtctgtttat ccgtgaaaag ttctggctag agagtgagcg agtcaaaaca
    28441 actcgtcttt ggtgctataa ggtcaatgtg agcgaccttg aagaagtgca acctggtctt
    28501 tacatgacca aagcaacctt cacttgccat cctacaaaat actttaaaga ctccgataca
    28561 cagagattga caagaagtgg gactttgacc gttcaaggtt ctgctcttgc ctttcctaaa
    28621 atcacaatcg ttggtcagag cgcttctgaa acttcattta caattgctgg tcaggtcatt
    28681 cgtcttgaac gactcactga gtcgcttgtg atggttaata atcctgacaa tccaagtttt
    28741 aaaacaacaa cagggaagcc agtcaaatgg tcaggggatt ttatcacagt tgatccagcg
    28801 aaagtgaaga atattggggt tgttttaggc ccaggtattc aatcgattga aatcgaaacg
    28861 gtttgggggt gggcataatt gctttatcta cttaataaag atgtaagaac cgttcgatgg
    28921 aacggggagc cacttcatga agcgacttcg gcgattgtga aagaaactat gaatggcgat
    28981 tttaccttga ctgtgaaata tcctatttct gattctggta tttaccagct catccaagaa
    29041 gatatgctga taaaggctcc gactcctgtc ttaggagcgc agctatttcg tatcaagaaa
    29101 cctgttgagc acaatgacca tctggaaatc acagcctatc acatttcaga tgatgtgatg
    29161 caacgatcta tcacacaaat gagtgtgact agtcagagtt gtggcatggc tcttgctcgc
    29221 atggtacaaa acaccaaaac ggctcttgga gacttctcat tcaacagtga tatccaggac
    29281 cgtaggacat tcaacacgac tgagacagaa accctgtact ctgtattgct ggacggcaag
    29341 catagtatcg ccggaacgtg ggaaggcgag ctggtgcgtg ataactttgc gatgactgta
    29401 aagaagagtc gtggtgagaa tcgtggtgtt gttattacaa cacataagaa tctgaaggac
    29461 taccaacgaa ccaaaaacag tcaaaatgtt gttacaagga ttcatgctcg atccacattt
    29521 aagcctgaag gtgctgaaaa ggaaacaact atcagagtga ctgttgatag tcctcttatt
    29581 aattcttatc cttatataaa cgaaaaagag tatgagaaca acaacgcaaa atccgttgaa
    29641 gagttgcaga agtgggcaca gtctaagttc tcaaatgagg gaattgacaa ggtctctgat
    29701 gctatcaaaa ttgaagctta tgaacttgat gggcaagtgg tccatatggg cgacacggtc
    29761 aatctcaaga gctggaaaca taatgtcgat gcattcaaga aagctattgc ttatgagttc
    29821 gatgccttaa aagaagaata catctctctg actttcgatg ataaggcagg tattggtggt
    29881 tctagatctt ctggtggcct atctagcgca gccgatgcaa ttcttggagt gacagaatct
    29941 gcacaagaaa tcgcccttga aaaggctctt caaaatgctg acttagactt tgatcataag
    30001 gctggattgc ttagacagga aatttctgac gatattgaac tggccaaagc cagagctgaa
    30061 gaagtcaaga gagaactgtc tgacactatc aatcagcgat ttaatagctt tgacaacggg
    30121 ccattgaaag aaactaagcg caaggctgag gaagctttgc gaaatgctgg cgcaagtacc
    30181 ctgcttgcac aggaagctaa gcggattggg ctggattctg tcgctagact tgaagcgttt
    30241 aagtcgcaga ctacgagcgc acaaacggct ctgtcgggtg acttggacgc tctgaaacgg
    30301 actatcgcga atgatattcg accgaagcaa gcacaggctg aagctgagat tgccaagcaa
    30361 gctgaagcac ttagccggac taaaaatgaa ctggctggcg caagtaccct acttgcacag
    30421 gaagctaagc ggattgagct ggattctgtt gctagacttg aagcgtttaa gtcgcagact
    30481 acgagcgctc agacggcttt gtcaggtgac ttggatgttc taaaacaaac tatcgcaaac
    30541 gatattcgac cgaagcaagc acaggctgaa gctgagattg ccaagcaagt tgaagcactt
    30601 agccggacta agaatgaact ggctggcgtg aagtcagcgc aagcgacgta taaggagacg
    30661 acgactcgta gactgtcaga actgaccaac ttggccaatg gtaaagccag caagtcagaa
    30721 cttacgcaaa cagctgagga gctggctagt cggattgcga gtgtgcaggc aggtagttca
    30781 cggaattact tcaggaattc acgttcaaga acgttcacaa caggaggtca agcggtatac
    30841 gactatcgaa cattcatagt tcctgatttc tggaagaaca gtgacaggtt caagcgtgat
    30901 tatgttcgca tatcttttga tgtgactttc cctgtcgccc tagtaaatga catgcctgct
    30961 atggtgcatt ttagtgctca tccatggtat gcctacagaa acttaatttt taaaggtgga
    31021 actgtcgaac gccaacattt tgagtttacg attgacttgt ctagttcttc tgaggactat
    31081 cagactaata atgtgttcat tcgttttggt actaattatg gatttcctgc tggtctgcag
    31141 gtcgtcattg agaacgctat gttatcggtt ggtaattatt ttccagccta tcaaccagcg
    31201 tatgaagacc aagaagaccg tgtctcagta gtcgaatcca actttaaaca gcgtgctgat
    31261 tcactcgacg ctggtgtaag aagcttgact gaaggcctta gaaccaaagc ggatatcagc
    31321 tcactcaatg tgactgctga aaatatccgg caatctgtga agagccttga gacagatacg
    31381 cagaacaagc taaatcagaa gttgagtcag gctgaatttg aggtgcgagc cggctctatc
    31441 cgtcaggaaa tcctgaacgc aaccaaggat aaagccagca agtcagaact cacgcagaca
    31501 gctgaggagc tggctagtcg gattgcgagt gtgcaggcat ccggtcgaaa tctattcttg
    31561 aactcactat tcaagcagga tattccaaaa acaggaattt ggacaacgag tacatatacg
    31621 gctactatcg atagcgaaag taagtatctt ggacacaagg ctcttaaaat tataggtttg
    31681 aatccatctg gccgtgatgg aggtaatccc aaggttactt atccagctct gggtcaattc
    31741 gggaaagtaa ttcccggaag tacgactaat caagatgtaa ccattagttt ttatgctaag
    31801 gcaaataaaa atggaataat gctaagatct cgattaggga atatcggata taaaactgga
    31861 aatgtgacat tgtcgacaga aattaagcga tatgttgtcc atattccaaa aggttggaca
    31921 aacgaatcca agcagaccac aaatgaatgg ttgttcaatt tcaaccagga aggaaccatt
    31981 tggatttgga tgccgaagtt tgaaataagc gatgtagata cttcttattc agaagctcct
    32041 gaagatatag aaggtcagat ttcaacagtt gaatcgacct tcaaacaacg agccaactaa
    32101 ctcgacgctg gtgtaagccg tctgactgaa ggccttagaa ccaaagtgga tatcagctca
    32161 ctcaacgtga ctgctgaaaa tattaggcag tcggtgaaga gtcttgagac agacacgcag
    32221 aacaagctaa atcagaagtt gagtcaggct gaatttgagg tgcgagcaag cggaatccgt
    32281 caggaaatcc tgaatgcaac caaggacaag gctgacaaga ccttggtaac agcggaggct
    32341 gggaagttga gagaggagct gacaagtctg tcggttggcg agaatctgtt tgtaaactca
    32401 gattttaaaa atctgaggga taacggacag cgttatacag ctaacggcaa gacctatcaa
    32461 aacatgattg cgccttactg gtacaatccg tacaatgctg gtattccaaa tgctcaaaat
    32521 atccagcatg ggtattttga cacggaaacg tttagtgata ctgtctttgc ctttaacgag
    32581 agcgacggct cccgacactg gaaagcattg tcaactgatt ttaaaatcgg agtcatctca
    32641 gctggagagt attacttttc agctgatttg tatgcgacag atttaggcac tcatatcaaa
    32701 tttggatttt actatcacaa ctcgactggc aaactcaatt tttacgcagg tcgaacaaaa
    32761 attgaagtta ctgaaaaagg ccgttggact aggctaggaa ttgacttaaa ggtcaatgat
    32821 gacattgacc tgacaaaaaa agtccaattt tacatttacg gctataattt tgctagcaac
    32881 tcaattttgt accttaaaaa gcctaaagtc tcgaaaggtc gcttaaaaag cgattggagc
    32941 ccagctctgg aagacaccga aggcctcatc actgaggcta aggcaacctt tgagcggaca
    33001 gctcagggct tgcgaaccga cttatcagct attcaggaat atgtaaataa agacggtcag
    33061 cgacaggaag ccctacagcg ctatactcgt gaggagagca cgagacaagc gacagcagtc
    33121 cgtgagctgg tcaatcgtga tttcgttggt aaggctactt atcaagaaga tgttaagggt
    33181 atcaatcaga ggattgaagc tgttaaaact agtgcgaata aagacatcgc tagtcaaatc
    33241 gctagctatc gtcaatctgt agatggtaag ttcacggata tttcaagtca gataactact
    33301 tataagcaag atgtgggcgg tcaaatcagt ggtctatcaa atagacttac aagcagtgag
    33361 caaggaacca ctactcagat ttcaaatatt tcaaatcgga taaacagtaa taaacaaggc
    33421 acagataatc agatttcaaa tttaaagact caggtcgcta caaacaagga taatgctgaa
    33481 cgacaaatgg gtagaatatc tgatcaggtt tctgcaaaca aagcgaatgc tgatagtcaa
    33541 tttgcgaatg tgaccaatca actagcgcga aaagtagaga ctactgactt ccagcgtgtt
    33601 aaggaaacca gtaaacttta cgagcggatt ttgggcaata ctgaaaatgg aattgcggat
    33661 aaggttgctc gcatggctct gaccaatcaa ctgtttcagg ttgaggttgg gaaatatagt
    33721 gtaagcggcc ctaacctcat taagaatagt gattttaaaa atggtacgaa tgaatggggc
    33781 tcaactcaaa atttaggaag attggttaag catagctttt atcacaacgg gcagaaagac
    33841 cttatgcgtt taagtaatgc aactaaaaac gaaaactttt tgtatagtca ccgttttaat
    33901 cttgaacgaa atactgacta tgtactgaat tttagaggat ttaacaacag tgctctcgca
    33961 agctatgatg tttatatttt gggacgaaga gcaggcgaga gcgatggatt cacaatcgtt
    34021 aagaaagttg ttagcagcaa gaaactatct acctctagat gcgaagatgt ctcagtaact
    34081 tttaattccg gagaaatgga taatgcttac attcgttttg ataacaatgg ctcatcatca
    34141 ggaacagctg atttgtatat tacagaagtt gacttgtaca aaggttataa acctagaaca
    34201 tggcaaccac atccagaaga tgcagtcgca gatgcgaata agaagcttga agccacgcaa
    34261 acaaaaatga ctcaactagc tggctcatgg gtagttgaaa acatcaactc ggctggagat
    34321 atcatctctg gaatcaatct tggcgccaat ggacataacc gctttgttgg gaaattgacc
    34381 cacatcactg gagagaccct gattgacaga gcagtcatca agtctgccat ggttgataag
    34441 ctcaaaacgg ccaattttga agctggttcg gtcacgacta cgatattaga cgctgaagcg
    34501 gtcacggctg ataaagtgag atttgatgct gcgtttatta gaaaaatgat tgcaaatgac
    34561 gcttttattg accaactgac atctaaacgt atcttctcta ctaaggttga gtccgtcatt
    34621 tctagttcaa ccttcctaga agcctatcaa ggccgaatcg gtggatttac acttggtcaa
    34681 tttgatcagg gtggcggtcg ctggatttca ggtgtcaatc agttctctgt tggtatgggg
    34741 aatggtgccg ggcatggggt gccggacagc cttctgggcg aactggggaa ataattggaa
    34801 ctatgccgga cctaaagcat ggaacgtcaa tactgatggg aaaatgtact gtaggaatga
    34861 agtcggtttt tatgatcaag tggatttttc gaattcatcg agagcaaact tctatgggaa
    34921 tactactttt tctcgttctc ctgtgttttc aaatggtatc gaacttggaa gtaaagatgt
    34981 gcttggtgat ggttggaatc ccaaaggcgg aaggaatgcg gttgtttggt ggaatcaggt
    35041 cggtagcggt agcgtgaagt attggatgga acaaaaatca gacagacgct taaaagagaa
    35101 catcacagat acagctgtga aagccttgga caaaatcaac agattaagaa tggttgcatt
    35161 tgatttcatc gaaaataaga aacacgagga gattggtcta atagctcaag aggctgaaac
    35221 catcgttcca agaattgtct cacgagatcc tgagaatcca gatggctatc tacatatcga
    35281 ctataccgct ttagttcctt acttaatcaa ggctattcaa gaattaaatc aaaaaataga
    35341 aaaaatggag aaaacaatag catgaataac aacatgttga ccaatatcgc acttaaagca
    35401 attcaggagt ttgctcttga aaatagaaaa cgaacacaca gattggagaa cttagaaaat
    35461 gaacacagaa cagcttaacc aagccttaca aatgacaatt cgtgaaatgt caacaacttc
    35521 aacagattcg atgattgcaa gtaatttctt gagtattcag ttgaatgagc aaagggaaga
    35581 gaatcaaaga cttcaagcac gagtggatga gctggaagct ctgcttgatg aacaaactaa
    35641 accagcagac aaaggagaat agacatggca gaaacaattc aaaacacaga taacttacta
    35701 gaccttacaa aaatcacaga accatttgat cttgcgagcg ctttgcgcta catgaaagaa
    35761 aatggagagt tcattcgttg caagaatgta agcgatgact tctatatgta tcgtgatgtt
    35821 caaaaacgtc ctgtgatcgt aaatggccgt cgccaattca aggatgttga aactgtttgg
    35881 gcgttcaacc agtggggggg ggtacaatca caacaatcaa cgtagccgtt ctgttgaatc
    35941 atgaattcta tatcatgaaa tttgatgcag agggcaatcc tgactggacg gatccaacgg
    36001 taaaacctaa agaataggag gtgtgtatgc aaattgaatt tttcaatttt ctaagaagtg
    36061 tcgtacagac tgaagatggt ttggtcttgt acgctctagc actgattgtc tcaatggaaa
    36121 tcattgattt tgtgacaggg acgattgcgg cgattatcaa tcctgacatc gagtacaaga
    36181 gcaaaatcgg cattaacggg ctccttcgta agatttcagg ggttctctta ctgatgatcc
    36241 tcattccggc gtccgttttg ttgcctgaaa agacaggttt tgtattcttg cactcaatct
    36301 atctcgggta catcgcattt acttttcaat ctctcattga aaattaccgc aaattaaaag
    36361 gaaatgttac tctttttcag ccgattgtaa aagtatttca gcgattactt gaaaaagatg
    36421 atgatacgaa aaaaggagaa taacaaatgc aacaaattac tgaaatcatt actaatggag
    36481 caatcagcat cctagtcatt ttggcagggg tggtagttag ggtagtcaag gaatacctcg
    36541 tcaaaaaagg tggagaaaag actatcaaga ttgttgaaat cttggccaag aacgcagtta
    36601 atgccgtgga gcaggtagct gctgaaactg gctacaaggg agatgaaaaa ctggcacagg
    36661 ctcgcgctaa aattcgtgca gagctgacca aatataatat cagtatgacg gacaaggact
    36721 tggacacctt tgtggagtca gccgtgaagc agatgaacga cgcttggaaa ggacaagagt
    36781 aatggatatc gatagaaaca gactacgtac aggcttgccc caggttgggg tgcagcctta
    36841 tcgacaagta catgctcact caacaggcaa ccgtaactca accgctcaaa atgaagctga
    36901 ttaccactat agaaaggacc ctgaactagg gttcttttca catgttgtcg gaaacggccg
    36961 catcatgcag gtaggacctg tgaacaacgg aagttgggat gttgggggcg gttggaatgc
    37021 tgagagttat gcagcggttg aactgattga aagccattca actaaggaag agtttatggc
    37081 tgactatcgc ctctatatcg aattgctacg caatctagca gatgaagcag gtttgccgaa
    37141 aacgcttgat acagggagtt tagctggaat taaaacgcac gagtattgca cgaataacca
    37201 accaaacaac cactcagacc acgttgaccc ttatccatat cttgcaagtt ggggcattag
    37261 ccgtgagcag tttaagcaag acatcgaaaa cggcttgagc gctgcgacag gctggcagaa
    37321 aaatggtact ggctactggt acgtacactc agacggctct tatccaaaag acaagtttga
    37381 gaaaatcaac ggtacctggt attatttcga tggctcaggc tatatgcttt cagaccgctg
    37441 gaagaagcac acagacggta attggtacta ctttgaccaa tcaggcgaaa tggccacagg
    37501 ctggaagaaa atcgctgaga agtggtacta ttttgatgta gaaggtgcca tgaagacagg
    37561 ctgggtcaag tacaaggaca catggtacta cttagacgct aaagaaggcg ccatggtatc
    37621 aaatgccttt atccagtcag cggacggaac aggttggtac tacctcaaac cagacggaac
    37681 actggcagat aagccagact tcacagtaga gccagatggc ttgattacag ttaaataaat
    37741 agaaaggaaa ctttctaaat tgttctttca ccgcaggctc aggcttgcgg tttttttgtt
    37801 tgtctgaatc aagaaagcgt ctaaccaacc gacaccaatg tcggtagcaa aataaatggt
    37861 ttgcctaaaa aattagagtt aagttctatt tttcaaaaac acgcattttg aacgattaga
    37921 aacagaaatc taaatcctat tgttcaaaaa aacgtttaca tgaaaaatag ggaggtgttt
    37981 tgttaaaaat aaaaacagtg atcgaaatca ctgcttatca gttgtagcaa attcataaag
    38041 tttttctgct gtgagaagtg ccattttgtc catgcttgtt tttccttttc tgaggtcaga
    38101 aacagtagtc catggaactc cagcaccttg ggaaatagca gatgtagaca tcgaactgtc
    38161 taacaattct tgaataactt ctctcatctt atttgtcctt tttatttttt agataaatat
    38221 atacattgat tgcaattata aaaatagcta ttgcactaac cattgcattt cctctttcca
    38281 tttgataaaa tagaggtgta aggggctttc gccccaacct cttagcgttt acctttttct
    38341 ttgacgggat ttcggtttac gctttttgtt ttgccttgcg accgttattg cggtcactag
    38401 acttgcgata gcagttaccg tttcaggaat attgtctatt gccttttcaa gtaacctgag
    38461 ccaatcttct ttgttcaact tcatcacccc ctttccttat cttgattata ttatatcacg
    38521 gtacaccgag aaagtcaagc gttttgatga agtttttttt aattttttca aaaaaaaata
    38581 gaccttgtcc agaggtcggg gagttggagg gggcaccctc caaaagcatt gatttaataa
    38641 ggttttattt tacctttttc ataataatct ccctatagag tcaccgcatt cggtggcttt
    38701 ttttgtgttg ggattcatga tataataata aaatcgataa gtaggaaaag agaaaagaga
    38761 tgtattatac gcttgaagaa aaagaagtct ttatgaggga ggctttgaga gaggctgaga
    38821 ttgctcttga acacgatgaa attccaattg gttgtgtgat tgtcaaagat ggggaaatca
    38881 ttggtcgtgg gcataatgcg cgtgaggaat tacagcgagc ggttatgcat gcggaaatta
    38941 tggctataga ggatgcgaac ttgagtgagg agagctggcg cttgctggat tgcacacttt
    39001 ttgtgaccat tgaaccttgt gtcatgtgta gtggagcgat tgggcttgcc cgcattccaa
    39061 atgtggtcta tggggctaaa aaccagaaat ttggcgctgc tgggagtttg tacaatatct
    39121 tgacagatga gcgtctcaat catcgtgtgg aggttgaaat aggaattttg gaagatgaat
    39181 gcgcagctat catgcaggat ttttttagaa atagacggaa aaaataattt tgcttttaaa
    39241 atgaatagga atgtgatata ataaatagtg gagcaacagt tctgcgtgaa gcgggtcagg
    39301 ggaggaatcc agcagcccta agcgatttga attgtgtgct ctttttttcg tgctttttcc
    39361 gaataaataa gatagaataa tctagaataa atgataatag aaaagagaaa attatgaaaa
    39421 ttcgtggttt tgaattggtt tcgagtttta cagatgaaaa tttattgccc aagcgtgaga
    39481 cagcgcatgc ggctggttac gacttaaagg ttgctgtgcg tacagttgtt gcgccaggag
    39541 agattgtctt ggttccgaca ggggttaagg cttatatgca gccgactgag gttctctacc
    39601 tctatgatcg ttcttcaaat cctcgtaaga agggcttggt tttaattaac tcagttgggg
    39661 tcattgatgg ggattattat ggaaatcctg gaaatgaagg gcatattttt gcgcagatga
    39721 agaatatcac agatcaagag gttgttcttg aagttgggga acgtattgtc caggctgttt
    39781 ttgctacttt cttaattgca gatggagatg cagctgatgg cgttcgaact ggtggatttg
    39841 gatcgacagg gcactagaat gaagattatc tttgtacgtc atggggagcc agattaccgt
    39901 gagttagagg agcgttctta tataggattt gggatagatt tggcaccctt gtctgagatg
    39961 ggacggcagc aagtccagaa attgagcaaa aatcctttac tctcgtcagc tgaaataatc
    40021 gtatcttctg cagtcacaag agctttagaa acggcttcgt atgtggtctg tgctacgggt
    40081 cttcctttaa gagtagagcc tttattacat gaatggcagg tctataaaac aggaatagaa
    40141 aactttgaaa cagctagaag actgttttta gaaaacaagg gggagttgct tcctaatagt
    40201 cctattcaat atgagacagc tacggaaatg aagtctcggt ttctagaatg tatgtctaag
    40261 tatcgagaac atcagactgt ggtagttgtt gctcatcgaa tgctcatgcg ccagtttgtg
    40321 ccaaatgaga agattgattt ttgccaagtg attgagtgtg agttagagat atagaaagag
    40381 gtttgtcatc gcaaagaaaa aagcgacatt tgtatgtcaa aattgtgggt ataattcccc
    40441 taaatatctg ggacgttgcc ccaactgtgg gtcttggtct tcttttgtgg aagaggttga
    40501 ggttgccgag gtcaagaatg cgcgtgtgtc cttgacaggt gagaaaacca agcccatgaa
    40561 actagctgag gtgacttcca tcaatgtcaa tcgaaccaag acggagatgg aggaattcaa
    40621 ccgtgtgctt ggaggcggag tggtaccagg aagtctcgtc ctcatcggtg gggatcctgg
    40681 gattgggaaa tcaactcttc tcctacaagt ctcaacccag ttgtcccaag tggggacagt
    40741 tctctatgtc agtggggagg agtctgccca gcagattaaa ttacgtgcag agcgcttagg
    40801 tgatattgat agtgagtttt atctctatgc agagaccaat atgcagagtg ttcgtgcaga
    40861 agtggagcgt atccagccag acttcttcat tattgactct atccagacca ttatgtctcc
    40921 tgagatttca ggggtgcagg ggtctgtttc tcaggtgcgt gaagtgaccg ctgaactcat
    40981 gcagttggcc aagaccaata acattgccat ctttatcgta ggtcatgtga ccaaagaagg
    41041 aaccttggct gggcctcgta tgttggagca tatggtggat acggtgcttt actttgaagg
    41101 ggagcgtcac cacacctttc gtattttgag agcggtcaaa aatcgttttg gttccactaa
    41161 tgagattggg atttttgaga tgcagtcggg cggcttggtt gaggtactca atccgagtca
    41221 agttttccta gaagagcgtt tggatggggc gactggttcc tccatcgttg taaccatgga
    41281 agggacgcgt ccgattttgg cggaggttca ggctttagta acaccgacca tgtttggaaa
    41341 tgccaagcgt actacgacag gacttgattt taaccgtgct agcttgatta tggctgtttt
    41401 ggaaaaacgg gcagggcttc tcttgcaaaa tcaggatgcc tatctcaaat ctgctggtgg
    41461 tgttaaattg gatgaacctg ccattgactt ggctgttgca gttgctattg cttcgagcta
    41521 caaagacaaa ccaactaatc ctcaggaatg ttttgtcgga gaactgggct tgacaggaga
    41581 gattcggcgc gtgaatcgta ttgagcaacg catcaacgaa gctgctaaac tgggctttac
    41641 taagatttat gtacctaaga attccttgac aggaatcact ctgcctaagg aaattcaggt
    41701 cattggcgtg acaacgattc aggaagtttt gaaaaaggtc tttgcataat ccgtgacaaa
    41761 ttctcttaaa aatgataaga taggagaaat atttgactat caaattttca aggagggaat
    41821 cgtgtcgtat tttgaacagt ttatgcaagc caatcaggct tatgttgccc tacatgggca
    41881 gttaaatctg ccacttaaac ccaaaacaag agtagctatt gtgacctgta tggactctcg
    41941 tctgcacgtt gcgcaagctc tgggcttggc acttggggat gctcatatct tgcggaatgc
    42001 aggtggtcga gtgactgaag acatgattcg ttcgctagtt atttcccagc aacaaatggg
    42061 gacaagagag attgtggtat tgcaccatac agactgtggt gctcagacct ttgaaaatga
    42121 accttttcag gagtatttaa aagaggaatt aggtgtagat gtgtcagacc aggatttctt
    42181 gcccttccaa gatatagaag agagtgtacg cgaggatatg caactgctta tcgagtctcc
    42241 cctaatacca gacgatgtca ttatctctgg tgccatttac aatgttgata caggaagtat
    42301 gacagtcgta gaattataaa tacttcattt agaaagaaag tgtatgaaga aaagcagtat
    42361 tttattgcta tgtattggtt tacagtatga aaccatctac tatacggacg gttcgaggtc
    42421 aggtgcggaa tatggactaa tgggaatttc tatctttcta gctctctttt acatgattcc
    42481 ggctctttat tttctcttcc gtattgggaa aaatgggaat tgccaaagaa ggttttgatt
    42541 ctgtctttat tgggagggat gttcctttca ggctggttgt ctagttttgc taatacttat
    42601 atccatgatt tactgggggt tcttttccca gatagtacat ttttaaatgc ctttgaaagt
    42661 gctattgtgg ctcctttggt agaagaaccc ttgaaattat tgccacttgt ttttgttttg
    42721 gctttgattc ctgtgcgaaa attaaaatct ttgtttttac ttggaattgc ttccggtttg
    42781 ggattccaaa tgattgagga tattggttat attcgtacgg atttgccaga gggctttgac
    42841 tttactattt cgcgaatttt agagcgtatc atctcaggaa ttgcctctca ctggactttt
    42901 tcaggtctag ctgtagtagg tgtttacttg ctttacagag cctataaagg acagaaggtt
    42961 ggcaagaaac agggccttat ttttctaggt ttagccttgg gaactcactt cttgtttaac
    43021 tctccttttg tggagttgga aacagagttg cctttagcga ttccagtggt tacggctatt
    43081 gctctctatg gtttttatca tgcttattgc tttgttgaga aacacaatga gttgatgacc
    43141 tagaatattt ttcaaaagaa tgatgcaagg gtacaaatat ggtgcccttc ttttattttt
    43201 gattgaaaaa tagtgcaaaa agcgctacaa tggtagatgg aaaatcttgt gaaaggcaca
    43261 agttatacat atataccgga ggaaatcatg tctttttctg atttaaagct gtttgccctt
    43321 tcttctaata aagaattggc agaacgtgtg gcgcaggaga ttgggataga gttggggaaa
    43381 tcaagtgttc gccaattttc agatggagag attcaggtca acattgaaga atcaatccgt
    43441 gggaaacacg tctttatctt acaatcaact agttcgcctg taaatgacaa tctgcttgaa
    43501 attttgatta tggtagatgc tttgaagcgt gcgagtgcag aatctgtcaa tgttgtcatg
    43561 ccttactatg ggtatgcacg tcaggataga aaggcgagag cgcgtgagcc aatcacttca
    43621 aaacttgtcg caaatatgct tgaagtagct ggagtggatc gtttattgac catcgacttg
    43681 catgctgcgc aaattcaagg attctttgat attcctgtgg atcatttgat gggtgctcct
    43741 ctgattgcag attattttga gcgtcgtggt atggttggtt ctgactatgt ggttgtcagc
    43801 ccggaccatg gaggggtgac tcgtgctcgt aagttggcag aatttttgaa aacatctatc
    43861 gctattattg ataaacgtcg tagcgttgat aagatgaata ctagtgaagt tatgaatatc
    43921 atcggtaagg ttgaaggcaa gacttgtatc ttgattgatg atatgattga taccgctgga
    43981 acgatttgtc atgcggcaga tgctcttgcg gaagctggtg ctgttgaagt ctatgcaagc
    44041 tgtacgcacc cagttctttc tggtcctgct acggacaata tccaaaaatc agctattaag
    44101 aaattggttg ttttggatac catctatctg ccagaagagc gtttgattga taagattgag
    44161 cagatttcaa tcgctcatct cctaggggat gctatcgtac gtattcatga aaaacgacca
    44221 ctttctccac ttttcgatat tgagaaaaaa atttaatgac caagcctgag atgattctca
    44281 ggttttttcg tcttttttcc gaataaatag atagtagcgg tgaatctagt aaagctagat
    44341 ttaaaactgt gatataataa aaagagaaga aatatgactg tacgtcatca gaagtttcag
    44401 cgaccatcat ttttgaacag tgatagcact tgaatcgacg ctttctaagg agaattctag
    44461 taggcatacc agtcgtttca agataaggaa ttttagaag
//
LOCUS       DAVBOG010000011        43433 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.011, whole genome shotgun sequence.
ACCESSION   DAVBOG010000011 DAVBOG010000000
VERSION     DAVBOG010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 43433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43433
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.011"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..73
                     /locus_tag="VQ865_000655"
     tRNA            1..73
                     /locus_tag="VQ865_000655"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:34..36,aa:Met,seq:cat)
     gene            87..160
                     /locus_tag="VQ865_000656"
     tRNA            87..160
                     /locus_tag="VQ865_000656"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Ile,seq:cat)
     gene            171..260
                     /locus_tag="VQ865_000657"
     tRNA            171..260
                     /locus_tag="VQ865_000657"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:207..209,aa:Ser,seq:tga)
     gene            271..344
                     /locus_tag="VQ865_000658"
     tRNA            271..344
                     /locus_tag="VQ865_000658"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:305..307,aa:Met,seq:cat)
     gene            348..420
                     /locus_tag="VQ865_000659"
     tRNA            348..420
                     /locus_tag="VQ865_000659"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:381..383,aa:Phe,seq:gaa)
     gene            440..510
                     /locus_tag="VQ865_000660"
     tRNA            440..510
                     /locus_tag="VQ865_000660"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:472..474,aa:Gly,seq:tcc)
     gene            546..619
                     /locus_tag="VQ865_000661"
     tRNA            546..619
                     /locus_tag="VQ865_000661"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:580..582,aa:Ile,seq:gat)
     gene            626..713
                     /locus_tag="VQ865_000662"
     tRNA            626..713
                     /locus_tag="VQ865_000662"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:660..662,aa:Ser,seq:gct)
     gene            complement(839..1774)
                     /locus_tag="VQ865_000663"
     CDS             complement(839..1774)
                     /locus_tag="VQ865_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     synthetase/biotin operon repressor"
                     /protein_id="HET3135054.1"
                     /translation="MKSYQAVYQILSKETDYISGEKIAEKLSLSRTAIWKAIKRLEQE
                     GIEIDSIKNRGYKLMNGDLILPEILEENLPIKVSFKPETKSTQLDAKEAIDLGHEANT
                     LYLASYQTAGRGRFQRSFYSPQGGIYMTLHLKPNLPYDKLPSYTLLVAGAVYKAIKNL
                     TLIDVDIKWVNDIYLNNHKIGGILTEAMTSVETGLVTDIIIGVGINFTIKDFPQELKE
                     KAASLFKATAPITRNELIIEIWRAFFETPAEELLYLYKKQSFILGKEVTFTLEQKDYK
                     GLAKDISENGKLLVQCDNGKEIWLNSGEISLNSWK"
     gene            complement(1771..2631)
                     /locus_tag="VQ865_000664"
     CDS             complement(1771..2631)
                     /locus_tag="VQ865_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000959966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HET3135055.1"
                     /translation="MLVFSEYQTGTIDLALSFYGYEECTPNYSFGPAIRDTYVLHYIT
                     KGQGKFHYKGKIVDLKEGDFFLLKPEELTFYQADSKEPWAYYWLGITGGKAPDYFALS
                     QISDQSYLIQSETCHTQTTAKLISDIVRFAQITKSSELAQLHIMGQLHELMFHLGTIA
                     PNQKKKNISSTHQLYLECKRLIDSHYPQSLTIQDLAKELSVHRSYLSSVFKEFNTLSP
                     KEYLLYVRMHRARQLLENTQESIKVIAYSVGFSDPLHFSKAYKQYFNQTPSHTRKEYS
                     QYQLVRKATL"
     gene            2739..4901
                     /locus_tag="VQ865_000665"
     CDS             2739..4901
                     /locus_tag="VQ865_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000538915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HET3135056.1"
                     /translation="MGVRIENNLFYVESKNLSLIIENRNGYLLLKHLGKTIKNYKGSN
                     SVYERDHAFSGNPTATNRTFSLDTQRQIFGQHGLGDFRKPTIQVQHSVTEVTDFRFVE
                     AKILKGQNGPQGLPSPHSMDDTETLVLMLEDSKAQLSLTLYYTTFNNDATIASYSKLD
                     NNSNQEVVIHKDFSFMADFPAADYEIVTLQGAYAREKTVRRQQVEQGIFSISSNRGAS
                     GHAQTPALLLCEQGVTEDAGNVFAIQLMYSGNFEAFVQKNQLNEVRVAIGINPENFSW
                     KLAPEEYFETPVALVTHSDQGLTGISHESQNFVLKHIMLSEFSKKERPILINNWEATY
                     FDFQREKLLELADEAKKVGIELFVLDDGWFGNRFDDNRALGDWVVNEEKLGGSLESLI
                     SAIHERGLQFGLWLEPEMISVDSDLYRQHPDWAIQVPGYEHTYSRNQLVLNLANPQVV
                     EYLKSVLDQLLFYHDIDYIKWDMNRNITKLGNGLTYLETQMQSHQYMLGLYELVSYLT
                     EKHSHILFESCSGGGGRNDLGMMRYFPQVWASDNTDAIARLPIQYGSSYLYPTISMGA
                     HVSAVPNHQMGRMTPLETRGLVAMMGNLGYELDLTNLSDEEKATIANQVNLYKELRPV
                     VQLGQQYRLINPDTVSNEAAVQFNYGNQTIVTYVRVLSVVETMETTLKLKDLDEEGLY
                     KLQENGEVYSGAELMYAGLTVILSQGDFLSRQYIFRKL"
     gene            4993..6252
                     /locus_tag="VQ865_000666"
     CDS             4993..6252
                     /locus_tag="VQ865_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3135057.1"
                     /translation="MEWYKKIGLLATTGLALFGLGACSNYGKSADGTVTIEYFNQKKE
                     MTKTLEEITRDFEKENPKIKVKVVNVPNAGEVLKTRVLAGDVPDVVNIYPQSIELQEW
                     AKAGVFEDLSNKDYLKRVKNGYAEKYAVNEKVYNVPFTANAYGIYYNKDKFEELGLKV
                     PETWDEFEQLVKDIVAKGQTPFGIAGADAWTLNGYNQLAFATATGGGKEANQYLRYSQ
                     PNAIKLSDPIMKDDIKVMDILRINGSKQKNWEGAGYTDVIGAFARGDVLMTPNGSWAI
                     TAINEQKPNFKIGTFMIPGKEKGQSLTVGAGDLAWSISATTKHPKEANAFVEYMTRPE
                     VMQKYYDVDGSPTAIEGVKQAGEDSPLAGMTEYAFTDRHLVWLQQYWTSEADFHTLTM
                     NYVLTGDKQGMVNDLNAFFNPMKADVD"
     gene            6266..7132
                     /locus_tag="VQ865_000667"
     CDS             6266..7132
                     /locus_tag="VQ865_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3135058.1"
                     /translation="MKKVLQKYWAWAFVVIPLLLQAIFFYVPMFQGAFYSFTNWTGLT
                     YNYKFVGLNNFKLLFMDPKFMNAIGFTAIIAIAMVVGEIALGIFIARVLNSKIKGQTF
                     FRAWFFFPAVLSGLTVALIFKQVFNYGLPAIGNALHIEFFQTSLLGTKWGAIFAAVFV
                     LLWQGVAMPIIIFLAGLQSIPTEITEAARIDGATSKQVFWNIELPYLLPSVSMVFILA
                     LKGGLTAFDQVFAMTGGGPNNATTSLGLLVYNYAFKNNQFGYANAIAVILFFLIVVIS
                     IIQLRVSKKFEI"
     gene            7146..7979
                     /locus_tag="VQ865_000668"
     CDS             7146..7979
                     /locus_tag="VQ865_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3135059.1"
                     /translation="MKQDERKALIGKYILLILGSVLILVPLLATLFSSFKPTKDIVDN
                     FFGFPTNFTWDNFSRLLADGIGGYYWNSVVITVLSLLAVMIFIPMAAYSIARNMSKRK
                     AFTIMYTLLILGIFVPFQVIMIPITVMMSKLGLANTFGLILLYLTYAIPQTLFLYVGY
                     IKISIPESLDEAAEIDGANQFTTYFRIIFPMMKPMHATTMIINALWFWNDFMLPLLVL
                     NRDSKMWTLPLFQYNYAGQYFNDYGPSFASYVVGIISITIVYLFFQRHIISGMSNGAV
                     K"
     gene            7980..8060
                     /locus_tag="VQ865_000669"
                     /pseudo
     CDS             7980..8060
                     /locus_tag="VQ865_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ865_000670"
     CDS             8337..9779
                     /gene="gtfA"
                     /locus_tag="VQ865_000670"
                     /EC_number="2.4.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001122330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose phosphorylase"
                     /protein_id="HET3135060.1"
                     /translation="MPIQNKTMLITYSDSLGNNLKDLYDNLEEHFGDAIGGVHLLPFF
                     PSTGDRGFAPVDYDEVDSAFGDWEDVKHLGEKYYLMFDFMINHISRQSKYYKDYQEKH
                     EASEFKALFLNWDKFWPENRPTQSDVDLIYKRKDRAPKQEIVFEDGSVEHLWNTFGEE
                     QIDLDVTKEVTMEFIRKTIQHLASNGCDLIRLDAFAYAVKKLDTNDFFVEPDIWDLLD
                     KVRDIAAEYGTELLPEIHEHYSIQFKIADHDYYVYDFALPMVTLYTLYSSRTERLAKW
                     LKMSPMKQFTTLDTHDGIGVVDVKDILTDEEIDYASNELYKVGANVKRKYSSAEYNNL
                     DIYQINSTYYSALGDDDVKYFLARLIQAFAPGIPQVYYVGLLAGKNDLKLLEETKEGR
                     NINRHYYSNEEIAKEVQRPVVKALLNLFSFRNRSEAFDLEGTTEIETPTAHSIVIKRQ
                     NKDKSVTAVAEIDLQNQTYRVIENGVEVTF"
     gene            9917..11110
                     /locus_tag="VQ865_000671"
     CDS             9917..11110
                     /locus_tag="VQ865_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008293041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HET3135061.1"
                     /translation="MKSIGFIEKLKGLSSKELILLGIILSIFLPFYLFVVVLCLYIIS
                     LIFTGDMKSILQKMGEHPMLLLFLSYSTVISILAQNWMGLVASVGMFLFTIFFLHYQS
                     ILSHKFFRLILQFVLFGSVLSAAFASLEHFQIVKKFNYAFLSPNMQVWHQNRAEVTFF
                     NPNYYGIICCFCIMIAFYLFTTTKLNWLKVFCVIAGFVNLFGLNFTQNRTAFPAIIAG
                     AIIYLFTTIKNWKAFWLSIGVFAIGLSFLFSSDLGVRMGTLDSSMEERISIWDAGMAL
                     FKQNPFWGEGPLTYMHSYPRIHAPYHEHAHSLYIDTILSYGIVGTILLVLSSVAPVRL
                     MMDMSQESGKRPIIGLYLSFLTVVAVHGIFDLALFWIQSGFIFLLVMCSIPLEHRMLV
                     SDMTD"
     gene            11797..13776
                     /locus_tag="VQ865_000672"
     CDS             11797..13776
                     /locus_tag="VQ865_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000742236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135062.1"
                     /translation="MKKNRVFATAGLVLLAAGVLAACSSSKSSDSSAPKAYGYVYTAD
                     PETLDYLISSKNSTTVVTSNGIDGLFTNDNYGNLAPAVAEDWEVSKDGLTYTYKIRKG
                     VKWFTSDGEEYAEVTAKDFVNGLKHAADKKSEAMYLAENSVKGLADYLSGTSTDFSTV
                     GVKAVDDYTLQYTLNQPEPFWNSKLTYSIFWPLNEEFETSKGSDFAKPTDPTSLLYNG
                     PFLLKGLTAKSSVEFVKNEQYWDKENVHLDTINLAYYDGSDQESLERNFTSGAYSYAR
                     LYPTSSNYSKVAEEYKDNIYYTQSGSGIAGLGVNIDRQSYNYTSKTTDSEKVATKKAL
                     LNKDFRQALNFALDRSAYSAQINGKDGAALAVRNLFVKPDFVSAGEKTFGDLVAAQLP
                     AYGDEWKGVNLADGQDGLFNADKAKAEFAKAKKALEADGVQFPIHLDVPVDQASKNYI
                     SRIQSFKQSVETVLGVENVVVDIQQMTSDEFLNITYYAANASSEDWDVSGGVSWGPDY
                     QDPSTYLDILKTTSSETTKTYLGFDNPNSPSVVEVGLKEYDKLVDEAARETSDLNVRY
                     EKYAAAQAWLTDSSLFIPAMASSGAAPVLSRIVPFTGASAQTGSKGSDVYFKYLKLQD
                     KVVTKEEYEKAREKWLKEKAESNEKAQKELASHVK"
     gene            13843..15339
                     /locus_tag="VQ865_000673"
     CDS             13843..15339
                     /locus_tag="VQ865_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135063.1"
                     /translation="MKKYIFMRVLRSLVSIFLVTTLTYTIIYTLVPRKLIFKQDPNYN
                     KIATTADKRDNYENTVFERMGYIEYYDTKELQEKASSMDSSVTVEANATNKAIYEKYI
                     NQLGHGWTLGEFTESGQFYATREIPIFERVFHFYANLIDIDHTNKIQDPENPDLKRYL
                     RFENDPAIGWSLVGSGTKHKYLLYFNSQFPFVHQNFVNLNLGDSYPTYANTPVLQVIT
                     QGQGQTKTAQVQFPTGKKTSSVNIYSRTYKSPSQADSREVASYGKDDPYTATESNYQY
                     PSMIVSSAITGLIGLVLAYALAVPLGSAMARFKNTWIDSLSTGALTFLLALPTIALVY
                     IVRLIGSSIALPDSFPILGAGDWRSYVLPAVILGLLGAPGTAIWIRRYMIDLQSQDFV
                     RFARAKGLSEKEISNKHIFKNAMVPLVSGIPGAIIGVIGGATLTETVFAFPGMGKMLI
                     DSVKASNNSMVVGLVFIFTCISIFSRLLGDIWMTIIDPRIKLTEKGGK"
     gene            15339..16265
                     /locus_tag="VQ865_000674"
     CDS             15339..16265
                     /locus_tag="VQ865_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135064.1"
                     /translation="MSTIDKEKFQFVKRDDFASETIDAPAYSYWKSVFKQFMKKKSTV
                     VMLGILVAIILISFIYPMFSKFDFNDVSKVNDFSVRYIKPNAEHWFGTDSNGKSLFDG
                     VWFGARNSILISVIATVINLVIGVFVGGIWGISKSVDRVMMEVYNVISNIPPLLIVIV
                     LTYSIGAGFWNLIFAMSVTTWIGIAFMIRVQILRYRDLEYNLASRTLGTPTLKIVAKN
                     IMPQLVSVIVTTMTQMLPSFISYEAFLSFFGLGLPITVPSLGRLISDYSQNVTTNAYL
                     FWIPLTTLVLVSLSLFVVGQNLADASDPRTHR"
     gene            16274..17341
                     /locus_tag="VQ865_000675"
     CDS             16274..17341
                     /locus_tag="VQ865_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135065.1"
                     /translation="MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALV
                     GESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDLTALSSHKDWEQIRGAKIATIFQ
                     DPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
                     SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITH
                     DLGVVASIADKVAVMYAGEIVEYGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSI
                     PGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAKTWLLHEDAPKVEKP
                     AVIANLHDKIREKMGFAHLAD"
     gene            17352..18278
                     /locus_tag="VQ865_000676"
     CDS             17352..18278
                     /locus_tag="VQ865_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135066.1"
                     /translation="MSEKLVEIKDLEISFGEGSKKFVAVKNANFFINKGETFSLVGES
                     GSGKTTIGRAIIGLNDTSNGDIIFDGQKINGKKSREQAAELIRRIQMIFQDPAASLNE
                     RATVDYIISEGLYNHRLFKDEEERKEKVQSIIREVGLLAEHLTRYPHEFSGGQRQRIG
                     IARALVMQPDFVIADEPISALDVSVRAQVLNLLKKFQKELGLTYLFIAHDLSVVRFIS
                     DRIAVIYKGVIVEVAETEELFNNPIHPYTQALLSAVPIPDPILERKKVLKVYDPSQHD
                     YETDKPSMVEIRPGHYVWANQAELARYQKGLN"
     gene            18769..19284
                     /locus_tag="VQ865_000677"
     CDS             18769..19284
                     /locus_tag="VQ865_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000512060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3135067.1"
                     /translation="MGILLTSLISLHQLKADKKRDVFRIGISQFITHQSLDATREGFV
                     DELAKQGYVEGENIEIDLQNAQGEQRNLKTISQQLAESSDVVLAIARPSAQSLANTTQ
                     TPPVIFSAVTDPVSAKLVESREHPGGNVTGTSDQSSDAISTQINLIKKVLPKAKTIGI
                     LYTQSEPNSVV"
     gene            19306..19707
                     /locus_tag="VQ865_000678"
     CDS             19306..19707
                     /locus_tag="VQ865_000678"
                     /inference="COORDINATES: protein motif:HMM:NF016292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135068.1"
                     /translation="MKEKGFTVVEKTILDSNNVKAAAESLMAEVDMVFVPTDNIISST
                     METVKQVSIKHKVPVFGGSTEMIAVGDLYNYGTNYEELGRQTARMLIRVLKGEKPENI
                     AVELPEKLELHTNQEMADALGIDISKLEGKE"
     gene            19719..20596
                     /locus_tag="VQ865_000679"
                     /pseudo
     CDS             19719..20596
                     /locus_tag="VQ865_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012086.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
     gene            20609..21412
                     /locus_tag="VQ865_000680"
     CDS             20609..21412
                     /locus_tag="VQ865_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000157668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3135069.1"
                     /translation="MASLLTLENIHKTFEAGTVNENHVLKGLDLEVEEGDFIYVIGGN
                     GAGKSTLMNILAGNLSVDEGDLLLAGKSIKNLSVRKRAKDIARVFQYPKMGTASRLTI
                     EENMAIALRRGQKRGLGWGVKEKDRIQFQEALKELNIGLENRLKVDTQYLSGGQRQAL
                     TLVMAALVKPKLLLLDEHTAALDPKTSQMVMDLTQKIVEHHQWTTLMITHDMNHAIEY
                     GNRLIMLYQGKIVVDVKGEEKKHLTVEDLMHLFQKNSGQSLVSDELVLG"
     gene            complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ865_000681"
     CDS             complement(21445..22155)
                     /gene="treR"
                     /locus_tag="VQ865_000681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HET3135070.1"
                     /translation="MKKYQQLFKQIQETIQNETYAVGDFLPSEHDLMEQYQVSRDTVR
                     KALSLLQEEGLIKKIRGQGSQVVKEETVNFPVSNLTSYQELVKELGLRSKTNVVSLDK
                     IIIDKKSSLITGFPEFRMVWKVVRQRVVDDLVSVLDTDYLDMELIPNLTRQIAEQSIY
                     SYIENGLKLLIDYAQKEITIDHSSDRDKILMDIGKDPYVVSIKSKVYLQDGRQFQFTE
                     SRHKLEKFRFVDFAKRKK"
     gene            22340..24307
                     /gene="treP"
                     /locus_tag="VQ865_000682"
     CDS             22340..24307
                     /gene="treP"
                     /locus_tag="VQ865_000682"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HET3135071.1"
                     /translation="MGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVK
                     AIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVV
                     QRVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFL
                     WLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAA
                     NWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPA
                     LILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAI
                     DTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTE
                     PALFGVNVKYIYPFVAGMTGSALAGMLSVTFNVTAASIGIGGLPGILSIQPQYMLPFA
                     GTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVNHEPVELTSVEII
                     SPLTGQVKELSQATDPIFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVS
                     DEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVI
                     ITNQDAYTATIPGTYPTTIQAGASLMVATRI"
     gene            24485..26110
                     /gene="treC"
                     /locus_tag="VQ865_000683"
     CDS             24485..26110
                     /gene="treC"
                     /locus_tag="VQ865_000683"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HET3135072.1"
                     /translation="MTLDKGKVVYQIYPKSYKDTTENGIGDFRGIIGKIPYLAKLGVD
                     MVWLNPFYPSPQRDNGYDISDYMAVDPLFGDMADFEEMVCIGKEHKIDFMLDMVLNHC
                     STEHEWFQKALAGDKYYQDFFFIQDQPTDWQSKFGGSAWAPFGDTGKYYLHLFDETQA
                     DLNWRNPNVRKELFKVVNFWRDKGVKGFRFDVINLIGKDEVSVDCPENEGKPAYTDKP
                     IVHNYLRMMNQATFGSDDSFMTVGEMSSTTMENCVLYSSPDRQELSMTFNFHHLKVDY
                     KDGQKWTLAPFDFEELKSLYHSWGKEMSDKDGWSALFWNNHDQPRALNRFVDIQNFRK
                     EGATMLAASIHLSRGTPYIYMGEEIGMIDPDYDSMADYVDVESLNAYQMLLEEGKSQQ
                     EAFQIIQAKSRDNSRIPMQWDASENAGFSTGTPWLKAGKSYKYINVENEIQGPIFTFY
                     QDLIRLRKEMPIISEGSYKPAFEDSKQVYAFERQFEDQKLLVLNNFYAKEVEIDLPAV
                     YQNGQILISNYEDAEVSEKILLKPYQTLAIYVN"
     gene            26252..26500
                     /locus_tag="VQ865_000684"
     CDS             26252..26500
                     /locus_tag="VQ865_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HET3135073.1"
                     /translation="MDLLLAIVLIVLAFLGGALGGMYLVRKQIEKEFADNPRLNAEAV
                     RTLLSANGQKPSEAKVQQVYHQIIRQQKAALANNKKKK"
     gene            26707..27501
                     /gene="racE"
                     /locus_tag="VQ865_000685"
     CDS             26707..27501
                     /gene="racE"
                     /locus_tag="VQ865_000685"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HET3135074.1"
                     /translation="MDNRPIGFLDSGVGGLTVVRELMRQLPHEEIVYIGDSARAPYGP
                     RPAEQIREYTWQLVNFLLTKDVKMIVIACNTATAVVWEEIKAQLDIPVLGVILPGASA
                     AIKSSQGGKIGVIGTPMTVQSDIYRQKIHDLDPDLQVESLACPKFAPLVESGALSTSV
                     TKKVVYETLRPLVGKVDSLILGCTHYPLLRPIIQNVMGPKVQLIDSGAECVRDISVLL
                     NYFEINRGRDAGPLHHRFYTTASSQSFAQIGEEWLEKEIHVEHVEL"
     gene            27498..28469
                     /locus_tag="VQ865_000686"
     CDS             27498..28469
                     /locus_tag="VQ865_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000182414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-triphosphate diphosphatase"
                     /protein_id="HET3135075.1"
                     /translation="MTNKIYEYKDDQDWYVGSYSIFGGVNSLSDYQTDFPLFEFSKIF
                     GDEEYGFPLSVTVLRYGSTYRLFSFVVDMLNQEMGRNLEVIQRHGALLLVENGQLLYV
                     ELPKEGVNVHDFFETSKVRETLLIATRNEGKTKEFRAIFDKLGYDVENLNDYPDLPEV
                     AETGMTFEENARLKAETISQLTGKMVLADDSGLKVDVLGGLPGVWSARFAGVGATDRE
                     NNAKLLHELAMVFELKDRSAQFHTTLVVASPNKESLVVEADWSGYINFEPKGENGFGY
                     DPLFLVGETGESSAELTLEEKNSQSHRALAVKKLLEVFPSWQSKPSL"
     gene            28445..28966
                     /locus_tag="VQ865_000687"
     CDS             28445..28966
                     /locus_tag="VQ865_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001118598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HET3135076.1"
                     /translation="MAKQTIIVMSDSHGDSLIVEEVRDRYVGKVDAVFHNGDSELRPD
                     SPLWEGIRVVKGNMDFYAGYPERLVTELGSTKIIQTHGHLFDINFNFQKLDYWAQEEE
                     AAICLYGHLHVPSAWMEGKILFLNPGSISQPRGTIRECLYARVEIDDSYFKVDFLTRD
                     HEVYPGLSKEFSR"
     gene            28963..29424
                     /locus_tag="VQ865_000688"
     CDS             28963..29424
                     /locus_tag="VQ865_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3135077.1"
                     /translation="MIAKEFETFLLGQEETFLTPAKNLAVLIDTHNADHATLLLSQMT
                     YTRVPVVTDEKQFVGTIGLRDIMAYQMEHDLSQEIMADTDIVHMTKTDVAVVSPDFTI
                     TEVLHKLVDESFLPVVDTEGIFQGIITRKSILKAVNALLHDFSKEYEIRCQ"
     gene            29415..30155
                     /gene="xerD"
                     /locus_tag="VQ865_000689"
     CDS             29415..30155
                     /gene="xerD"
                     /locus_tag="VQ865_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004245562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HET3135078.1"
                     /translation="MPMRDRISAFLEEKQGLSVNSKQSYKYDLEQFLDMVGERISETS
                     LKIYQAQLANLKISAQKRKISACNQFLYFLYQKGEVDSFYRLELAKQAEKKTEKPEIL
                     YLDSFWQESDHPEGRLLALLILEMGLLPSEILAIKVADINLDFQVLRISKASQQRIVT
                     IPTALLSELEPLMGQTYLFERGGKPYSRQWAFRQLESFVKEKGFPSLSAQVLREQFIL
                     RQIENKVDLYEIAKKLGLKTVLTLEKYR"
     gene            30155..30883
                     /locus_tag="VQ865_000690"
     CDS             30155..30883
                     /locus_tag="VQ865_000690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000351912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HET3135079.1"
                     /translation="MDIKLKDFEGPLDLLLHLVSKYQMDIYDVPITEVIEQYLAYVST
                     LQAMRLEVTGEYMVMASQLMLIKSRKLLPKVAEVTDLGDDLEQDLLSQIEEYRKFKLL
                     GEHLEAKHQERAQYYSKAPTELIYEDAELVHDKTTIDLFLAFSNILAKKKEEFAQNHT
                     TILRDEYKIEDMMIIVKESLIGRDQLRLQDLFKEAQNVQEVITLFLATLELIKTQELI
                     LVQEESFGDIYLMEKKEESQVPQS"
     gene            30902..31471
                     /locus_tag="VQ865_000691"
     CDS             30902..31471
                     /locus_tag="VQ865_000691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein B"
                     /protein_id="HET3135080.1"
                     /translation="MSTLAKIEALLFVAGEDGIRVRQLAELLSLPPTGIQQSLGKLAQ
                     KYEKDPDSSLALIETSGAYRLVTKPQFAEILKEYSKAPINQSLSRAALETLSIIAYKQ
                     PITRIEIDAIRGVNSSGALAKLQAFDLIKEDGKKEVLGRPNLYVTTDYFLDYMGINHL
                     EELPVIDELEIQAQESQLFGERIEEDENQ"
     gene            31458..32180
                     /locus_tag="VQ865_000692"
     CDS             31458..32180
                     /locus_tag="VQ865_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3135081.1"
                     /translation="MRINKYIAHAGVASRRKAEELIKQGLVTVNGQVVRELATTIKSG
                     DKVEVEGQPIYNEEKVYYLLNKPRGVISSVTDDKGRKTVVDLLPNVKERIYPVGRLDW
                     DTSGVLILTNDGDFTDEMIHPRNEIDKVYVARVKGVANKDNLRPLTRGLEIDGKKTKP
                     AVYEILKVDPVKNRSVVQLIIHEGRNHQVKKMFEAVGLQVDKLSRTRFGHLDLTGLRP
                     GESRRLNKKEISQLHTMAVTKK"
     gene            32180..32422
                     /gene="yidD"
                     /locus_tag="VQ865_000693"
     CDS             32180..32422
                     /gene="yidD"
                     /locus_tag="VQ865_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HET3135082.1"
                     /translation="MKRILIAPVRFYQRFISPVFPPSCRFELTCSNYMIQAIEKHGFK
                     GVLMGLSRILRCHPWSKTGKDPVPDRFSLKRNQEGE"
     gene            complement(32647..33612)
                     /locus_tag="VQ865_000694"
     CDS             complement(32647..33612)
                     /locus_tag="VQ865_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135083.1"
                     /translation="MKTSLKLYFTALVASFLLLLGACSTNSSTSQTETSSSAPTEVTI
                     KSSLDEVKLSKVPEKIVTFDLGAADTIRALGFEKNIVGMPTKTVPTYLKDLVGTVKNV
                     GSMKEPDLEAIAALEPDLIIASPRTQKFVDKFKEIAPTVLFQASKDDYWTSTKANIES
                     LASAFGETGTQKAKEELAKLDKSIQEVATKNESSDKKALAILLNEGKMAAFGAKSRFS
                     FLYQTLKFKPTDTTFEDSRHGQEVSFESVKEINPDILFVINRTLAIGGDNSSNDGVLE
                     NALIAETPAAKNGKIIQLTPDLWYLSGGGLESTKLMIEDIQKALK"
     gene            complement(33708..34460)
                     /locus_tag="VQ865_000695"
     CDS             complement(33708..34460)
                     /locus_tag="VQ865_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000764290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3135084.1"
                     /translation="MKLENIDKSIQKQDILQGISLEVSPQKLTAFIGPNGAGKSTLLS
                     IMSRLTKKDQGVLSIKGREIESWNSQELAQELTILKQKINYQAKLTVEELVSFGRFPY
                     SRGRLRSEDWEKIRETLNYLELTNLKDRYINSLSGGQLQRVFIAMVLAQDTDFILLDE
                     PLNNLDIKQSVSMMQILRRLVEELGKTIIIVLHDINMASQYADEIVAFKDGQVFSKGR
                     TDQIMQADLLSQLYEIPITLADINNKKICIYS"
     gene            complement(34457..35413)
                     /locus_tag="VQ865_000696"
     CDS             complement(34457..35413)
                     /locus_tag="VQ865_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HET3135085.1"
                     /translation="MQTKSKHTKLFWILIILAIGACLLYFWPITHLSAFAWKLRSQKI
                     IVYLLVAIATGISTISFQTLTENRFLTPSILGIESFYVLLQTLLLVFESKFLQLGKSP
                     ILEFLVLLLVQSLFFLALQGYLKTLMKQDLVFILLICLALRSLFRNISTFLQVLMDPN
                     EYDKLQNSLFASFQHLNTSILAIGSLIILALTIFFFRKAVVLDVLHLQRETAQILGLD
                     VEKEQKELLWGIVLLTSTATALVGPMAFFGFMLANLTYLIVKDYQHKLLFIVAILVGF
                     ISLTLGQALIERVFALEIRISMIIESVGGFLFFILLYRRARQ"
     gene            complement(35403..36362)
                     /locus_tag="VQ865_000697"
     CDS             complement(35403..36362)
                     /locus_tag="VQ865_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135086.1"
                     /translation="MKLSHYLIGLLLLLVFLSISIGTSDFSWGKLFDFDQQTWLLFQE
                     SRLPRTISILLTASSMSMAGLLMQTITQNQFAAPSTVGTTEAAKLGMVLSLFVFPSAS
                     LTQKMLFAFVSSIVFTLFFLAFMTIFTVKERWMLPLIGIIYSGIIGSVTEVIAYRFNL
                     VQSMTAWTQGSFSMIQTHQYEWLFLGLIILITVWKLSQTFTIMNLGKETSEGLGISYS
                     LLEKLALFLVALTTSVTMITVGGLPFLGVIVPNLVRKRYGDNLSQTKLMVALVGANLV
                     LACDILSRVLIRPYELSVSLLLGIIGSLVFILLLWRGGRKDAD"
     gene            complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ865_000698"
     CDS             complement(36785..37486)
                     /gene="galE"
                     /locus_tag="VQ865_000698"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3135087.1"
                     /translation="MTKTILVTGGTSYIGSHTVKALLNAGYQVHVLDNLSTGNRAAVD
                     SRASFKELDVYDASALKAYLEENQIDAVLHCAGEIVVSESIENPSKYFTANVAGMNQV
                     LKVLSEVGIQKIMFSSTASLYGNNCIDKPVTEDTLLDPVNPYAETKLMGERMIYWMAN
                     RYDWKYVIFRYFNVAGAEMDASNGLRVKNPTHIIPNINKTALGQHDSLKIFGDDYDTR
                     DGSCIRDYIYVLDLA"
     gene            37888..38952
                     /gene="pepA"
                     /locus_tag="VQ865_000699"
     CDS             37888..38952
                     /gene="pepA"
                     /locus_tag="VQ865_000699"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HET3135088.1"
                     /translation="MTTLFSKIKEVTELAAVSGHEAPVRAYLREKLTPHVDEVVTDGL
                     GGIFGIKHSEAVDAPRVLVASHMDEVGFMVSEIKPDGTFRVVEIGGWNPMVVSSQRFK
                     LLTRDGHEIPVISGSVPPHLTRGKGGPTMPAIADIVFDGGFADKDEAESFGIRPGDTI
                     VPDSSAILTANEKNIISKAWDNRYGVLMVSELAEALSGQKLGNELYLGSNVQEEVGLR
                     GAHTSTTKFDPEVFLAVDCSPAGDVYGGQGKIGDGTLIRFYDPGHLLLPGMKDFLLTT
                     AEEAGIKYQYYCGKGGTDAGAAHLKNGGVPSTTIGVCARYIHSHQTLYAMDDFLEAQA
                     FLQALVKKLDRSTVDLIKHY"
     gene            38974..39270
                     /locus_tag="VQ865_000700"
     CDS             38974..39270
                     /locus_tag="VQ865_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3135089.1"
                     /translation="MAEPNLESLIKDLYNHARHDLSEDLVAALLETAKKLPTTNEQLQ
                     AVRLSGLVNRELLLNPKHPAPELLNLARFIKREEAKYRGTATSALMYEELFKML"
     gene            39952..40395
                     /locus_tag="VQ865_000701"
     CDS             39952..40395
                     /locus_tag="VQ865_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3135090.1"
                     /translation="MKDGHLLAHHIRLLNGRIFQKLLSQDPEALYRGEQGKILAVLWN
                     SETGCATATDIALATGLANNTLTTMIKKLEEQKLVIVSPCGKDKRKKYLVLTELGKSQ
                     KEVGHRVSQKLDTIFYKGFSEEEIHQFEGFQERILANLKEKGNEV"
     gene            40399..41163
                     /locus_tag="VQ865_000702"
     CDS             40399..41163
                     /locus_tag="VQ865_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="HET3135091.1"
                     /translation="MSQQVKNAHNLYIHAIQDGRVAEAQAQSVGDTYIQHSTGVPDGK
                     EGFAAFFADFFERHPERQIKIVRTIEDGNLVFVHVHQYLNGGEAQWVTTDTFRADENG
                     RIVEHWDVIDYYRTPENDQLDQIFGDFEIKDLDKKAENKKLVRRFLTEIFQNGELEQW
                     SDYVADDLIQHNHEIGQGSAAYKNYVAEYSVTFDFVFQLLGQGNYVVSYGQTQIDGVA
                     YAQYDIFRLENGKIVEHWDNKEVMPKVEDLTNRGKF"
     gene            41178..41906
                     /locus_tag="VQ865_000703"
     CDS             41178..41906
                     /locus_tag="VQ865_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135092.1"
                     /translation="MIEYKNVALRYTEKDVLRDVNLQIEDGEFMVLVGPSGSGKTTML
                     KMINRLLEPTDGNIYMDGKRIKDYDERELRLSTGYVLQAIALFPNLTVAENIALIPEM
                     KGWSKEEITKKTEELLAKVGLPVAEYGHRLPSELSGGEQQRVGIVRAMIGQPKIFLMD
                     EPFSALDAISRKQLQVLTKELHKEFGMTTIFVTHDTDEALKLADRIAVLQDGEIRQVA
                     NPETILKVPATDFVADLFGGSVHD"
     gene            41899..43419
                     /locus_tag="VQ865_000704"
     CDS             41899..43419
                     /locus_tag="VQ865_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HET3135093.1"
                     /translation="MTNLIATFQDRFSDWLTALSQHLQLSLLTLLLAILLAIPLAVFL
                     RYHEKLADWVLQIAGIFQTIPSLALLGLFIPLMGIGTLPALTALVIYAIFPILQNTIT
                     GLKGIDPSLQEAGIAFGMTRWERLKKFEIPLAMPVIMSGIRTAAVLIIGTATLATLIG
                     AGGLGSFILLGIDRNNASLILIGALSSAVLAIAFNFLLKVMEKAKLRTIFSGFALVAL
                     LLGLSYSPALLAQKEKENLIIAGKIGPEPEILANMYKLLIEENTSMTATVKPNFGTTS
                     FLYEALKKGDIDIYPEFTGTVTESLLQPSPKVSHEPEQVYQVARDGIAKQDHLAYLKP
                     MSYQNTYAVAVPKKIAQEYGLKTISDLKKVEGQLKAGFTLEFNDREDGNKGLQSMYGL
                     NLNVATMQPALRYQAIQSGDIQITDAYSTDAELERYDLQVLEDDKQLFPPYQGAPLMK
                     EALLKKHPELERVLNTLAGKITESQMSQLNYQVGVEGKSAKQVAKEFLQEQGLLKK"
BASE COUNT        12539 a         8075 c         9795 g        13024 t
ORIGIN      
        1 gcggtgtagc tcagctggct agagcgtccg gttcataccc gggaggtcgg gggttcgatc
       61 cccttcgccg ctataatgat cttgtcggac ctttagctca gctggttaga gctctcggct
      121 cataaccgag tggtcgtagg ttcaagtcct acaaggtcca tttgaatatt ggaggattac
      181 ccaagtccgg ctgaagggaa cggtcttgaa aaccgtcagg cgtgtaaaag cgtgcgtggg
      241 ttcgaatccc acatcctcct tttatattaa cgcgggatgg agcagctcgg tagctcgtcg
      301 ggctcataac ccgaaggtcg taggttcaaa tcctgctccc gcaataaggc tcggtagctc
      361 agttggtaga gcaatggatt gaagctccat gtgtcggcgg ttcgattccg tctcgcgcca
      421 ttttattgat agtatttatg cgggtgtagt ttagtggtaa aactacagcc ttccaagctg
      481 ttgtcgcgag ttcgattctc gtcacccgct ttgaactttg ttcaaattac caagtttttt
      541 aacttgggcg cgtagctcag ttggttagag cgcacgcctg ataagcgtga ggtcggtggt
      601 tcgagtccac tcgtgcccat taattggaga attactcaag aggctgaaga ggacggtttg
      661 ctaaatcgtt aggtcgggta actggcgcaa gggttcgaat cccttattct ccgttttaat
      721 gagagtctgt aactctcttt tttattttta gagccaataa aacttcagat ccgtaaaact
      781 taattgaatt actaatctga agttattttt atatcgttta tattataatt gtgttatttt
      841 acttccaact attgagagaa atttcgccac tatttagcca gatttctttt ccgttatcac
      901 attgaactaa aagttttcca ttttctgaga tgtctttagc aagtcccttg tagtcttttt
      961 gctctagtgt gaaagtgact tcttttccta gaatgaatga ctgttttttg tataggtata
     1021 atagctcttc tgctggtgtt tcgaagaaag cacgccagat ttctatgatc aattcattcc
     1081 ttgttatagg agctgtagct ttaaataagc tggcagcttt ttcttttaat tcctgaggga
     1141 agtctttaat agtgaaattg atacctactc caataatgat atctgtgact aagccagttt
     1201 ctacagaggt cattgcttca gtaaggattc ctccaatttt atgattgttt agatagatat
     1261 cattgaccca ttttatgtcg acatctatta aagttaggtt cttaatggct ttgtagacag
     1321 ctccagctac aagtagtgtg taggatggta atttgtcata ggggagattt ggtttaagat
     1381 ggagtgtcat ataaatacca ccttgtggtg agtagaagga acgttgaaaa cggcctcggc
     1441 ctgctgtttg ataggaagct agatagaggg tatttgcttc atggcctaaa tcaattgctt
     1501 cttttgcatc tagttgtgtt gattttgttt cgggtttaaa gctgacttta attggaagat
     1561 tttcttctag aatctctgga agaataaggt caccattcat cagtttatat cctctatttt
     1621 tgatactatc aatttcaatg ccttcttgtt ctagtcgctt gatggctttc caaattgctg
     1681 ttcggcttag ggatagtttt tctgcgattt tttctccgct gatatagtcg gtttctttag
     1741 ataggatttg gtagacagct tggtaggatt tcataatgtt gcctttctta ctagttggta
     1801 ttgagagtat tcttttcttg tatgacttgg agtctgatta aagtattgtt tataagcttt
     1861 cgaaaaatgg agtggatctg aaaaacctac cgagtatgca attaccttga tggactcttg
     1921 ggtattttcg agaagttgtc tagctcggtg cattcgaacg tagagtaggt attctttggg
     1981 tgataaggta ttaaattctt tgaatacgct tgataagtag cttctgtgaa cggatagttc
     2041 ttttgctaaa tcttgaattg taagtgattg aggatagtgg ctatcaatta atcgtttgca
     2101 ttcaagatag agttggtggg ttgatgaaat attctttttt ttctgattgg gagcaatagt
     2161 tcccagatga aacatcagtt catgaagttg tcccatgata tggagttgag ctaattcact
     2221 tgattttgta atctgagcga agcggacaat gtctgagatg agttttgcag tagtctgggt
     2281 atgacaagtt tcagattgga tgagatagga ttgatcagaa atttgggaaa gagcaaaata
     2341 atcaggggct ttccctccag tgattcctaa ccagtagtag gcccaaggtt ctttactatc
     2401 tgcttgataa aaggttagtt cctctggttt taatagaaag aaatctcctt cttttaaatc
     2461 aacaatttta cccttgtaat gaaattttcc ttgtccttta gtaatgtaat gtagaacgta
     2521 tgtatcacga atggctggac caaaagagta attaggtgtg cattcctcat atccataaaa
     2581 gcttagggca aggtcgattg ttccagtctg gtattctgaa aaaactaaca tgtgctacct
     2641 cctacctaac attttaccat attcttgaga catttttcta ttttggaaag cgatttcagg
     2701 tgataaaata taatcaataa agtgatgagg tgaagtaaat gggagttagg atagagaata
     2761 atctatttta tgttgagagt aaaaatctaa gtttgattat tgaaaatcga aatggctact
     2821 tacttttgaa acatttagga aagactatta agaactataa aggttccaat agtgtttatg
     2881 aacgagacca tgccttttca ggaaatccaa cggctactaa tcgaaccttt agtttagata
     2941 ctcagcgaca gatttttgga caacatggct taggagattt taggaaacca accatacagg
     3001 ttcagcatag tgtaactgaa gtaacagact ttcgatttgt agaagcaaag attttaaaag
     3061 gtcagaatgg tccacagggc ttaccttctc cacatagcat ggacgataca gagactcttg
     3121 tcttaatgtt agaagattct aaggctcaac ttagtctgac tttgtattat actactttta
     3181 ataatgatgc gactattgct agctacagta aattagataa taatagtaat caggaagttg
     3241 tcatccataa agatttttct tttatggctg attttccagc tgcagattac gaaatagtaa
     3301 ctctgcaggg tgcttatgct cgtgaaaaga ctgttagacg tcaacaggta gaacaaggaa
     3361 tcttttcgat tagttcaaac cgaggtgctt ctggtcatgc tcaaacacca gctcttctac
     3421 tatgcgaaca aggagtcaca gaggatgctg ggaatgtgtt tgctattcaa ctaatgtata
     3481 gtggcaactt tgaagctttt gttcaaaaaa atcaattgaa tgaagttcgg gtggctattg
     3541 gcattaatcc agaaaacttt tcttggaagt tagctcctga ggaatacttt gaaacaccgg
     3601 tagctttagt gactcattca gatcagggat taactggtat tagtcatgaa agtcagaatt
     3661 ttgtactgaa gcacattatg ctaagtgaat tttctaaaaa agaacgtcca attctaatca
     3721 ataactggga agctacttac tttgactttc agagagaaaa actgttagag ttagcagatg
     3781 aagctaagaa agttggcatt gaactttttg tattagatga tggttggttt ggcaatcgtt
     3841 ttgatgataa tcgtgcttta ggtgattggg ttgttaatga ggaaaaactg ggtggaagtc
     3901 tagaaagtct gatttcagct atccatgaaa gaggtttgca gtttggactt tggttagaac
     3961 ccgaaatgat ttctgtagat agtgatttgt atcgtcaaca tcctgactgg gctattcagg
     4021 ttcctggcta tgagcatact tattctcgga atcaattagt acttaatctt gccaatcctc
     4081 aggtagtaga atacttgaaa agtgtcttag atcaactcct attttatcat gatattgatt
     4141 acattaaatg ggatatgaac cgcaatatca ctaagctagg gaatggatta acttatctag
     4201 agacacagat gcaatctcat cagtacatgc tggggcttta tgaactcgtt tcttatctga
     4261 cagagaagca cagccatatt ctctttgagt cctgctctgg tggtggtgga cgaaatgatc
     4321 ttggtatgat gcgctatttc ccacaagtct gggctagtga taatactgat gccattgcac
     4381 gtttaccaat tcaatacggt tcatcctatc tctatccaac catttctatg ggggctcatg
     4441 tgtcagcagt accgaatcat cagatgggac gaatgacacc attagaaaca cgtggccttg
     4501 tagcaatgat gggaaatttg ggctatgaac ttgatttgac aaatttatca gatgaagaga
     4561 aagctacgat tgctaatcag gtgaacttgt ataaagaatt acgaccagta gttcagttag
     4621 gacagcagta tagactaatt aatcctgata ctgtatccaa tgaagcagct gtacaattta
     4681 attacggaaa tcaaacgatt gtaacctacg ttcgcgtttt atctgttgta gagaccatgg
     4741 aaacaacttt aaaattaaaa gatttggatg aagagggact atataaatta caggaaaatg
     4801 gcgaagttta ctcaggtgca gaactaatgt atgcgggctt aactgttatc ttatcccaag
     4861 gagatttttt gagtagacag tatattttta gaaaactatg atatgtactg accccaaaag
     4921 ttagatttat tctgtctaac ttttggggtg cagttcaata agggtgtata aatttataaa
     4981 ggaggctttc taatggaatg gtataaaaaa atcggacttc ttgcaactac aggtttagct
     5041 ttgtttgggc tcggcgcttg ctccaactat ggtaaatctg cggatggcac agtgaccatc
     5101 gagtatttca accagaaaaa agaaatgacc aaaaccttgg aagaaatcac tcgtgatttt
     5161 gagaaggaaa accctaagat caaggtcaaa gtcgtcaatg taccaaatgc tggtgaagta
     5221 ttgaagacac gcgttctcgc aggagatgtg cctgatgtgg tcaatattta cccacagtcc
     5281 atcgaactgc aagaatgggc aaaagcaggt gtttttgaag atttgagcaa caaagactac
     5341 ctgaaacgcg tgaaaaatgg ctacgctgaa aaatatgctg taaacgaaaa agtttacaac
     5401 gttcctttta cagctaatgc ttatggaatt tactacaaca aagataaatt cgaagaactg
     5461 ggcttgaagg ttcctgaaac ctgggatgaa tttgaacagt tagtcaaaga tatcgttgct
     5521 aaaggacaaa caccatttgg aattgcaggt gcagatgctt ggacactcaa tggttacaat
     5581 caattagcct ttgcgacagc aacaggtgga ggaaaagaag caaatcaata ccttcgttat
     5641 tctcaaccaa atgccattaa attgtcggat ccgattatga aagatgatat caaggtcatg
     5701 gacatccttc gcatcaatgg ctctaagcaa aagaactggg aaggtgctgg ctataccgat
     5761 gttatcggag ccttcgcacg tggggatgtc ctcatgacac caaatgggtc ttgggcgatc
     5821 acagcgatta atgaacaaaa accgaacttt aagattggga ccttcatgat tccaggaaaa
     5881 gaaaaaggac aaagcttaac cgttggtgcg ggagacttgg catggtctat ctcagccacc
     5941 accaaacatc caaaagaagc caatgccttt gtggaatata tgacccgtcc agaagtcatg
     6001 caaaaatact acgatgtgga cggatctcca acagcgatcg aaggggtcaa acaagcagga
     6061 gaagattcac cgcttgctgg tatgaccgaa tatgccttta cggatcgtca cttggtctgg
     6121 ttgcaacaat actggaccag tgaagcagac ttccatacct tgaccatgaa ctatgtcttg
     6181 accggtgata aacaaggcat ggtcaatgat ttgaatgcct tctttaaccc gatgaaagcg
     6241 gatgtggatt aggagtagag agactatgaa aaaagtatta caaaaatatt gggcatgggc
     6301 ttttgtggtc atccccctct tgttacaagc aattttcttc tatgtgccga tgtttcaagg
     6361 agccttttac agttttacca actggacagg attgacttat aactacaaat ttgttggctt
     6421 aaacaacttt aagctcctct tcatggatcc aaaattcatg aatgcgattg gctttaccgc
     6481 aatcattgcg attgccatgg tggttggtga gattgcactc gggatcttca ttgcgcgtgt
     6541 cttgaattct aaaatcaaag gccaaacctt cttccgtgct tggttcttct tcccagctgt
     6601 tttatctggt ttgacagtgg ctttgatctt caagcaagtc ttcaactacg gtcttccagc
     6661 gattggaaat gcccttcata ttgaattttt ccaaaccagt cttttaggga ctaagtgggg
     6721 agcaatcttt gcggctgtct ttgtccttct ttggcaaggg gtggctatgc ccatcatcat
     6781 cttcctagct ggtttgcaat ctattccaac tgagattaca gaggcagcaa ggattgatgg
     6841 tgcgactagc aagcaagttt tctggaacat tgaattgcct tacttgctac caagtgtctc
     6901 tatggtcttt atcctagccc taaaaggtgg gctgactgcc tttgaccaag tctttgccat
     6961 gaccggtggt ggtccaaaca atgccacaac ctcacttggg ctcttggttt ataactatgc
     7021 ctttaaaaac aaccaattcg gttatgccaa tgccattgcc gtaatcttgt tcttcttaat
     7081 tgtagtgatt tcgatcatcc aattgagagt atctaagaaa tttgaaattt aagaggagaa
     7141 gcatgatgaa acaagatgaa agaaaagccc tgattggcaa atacattcta ttgattctag
     7201 gatcggttct gattttagtg ccgctccttg ctaccctctt tagttccttc aaacccacta
     7261 aggatattgt agataatttc tttggctttc caaccaactt cacatgggac aactttagcc
     7321 gtctcttagc tgatgggatt ggaggctatt attggaactc tgtcgtcatc actgtcttgt
     7381 ctttacttgc agtaatgatc tttatcccta tggcagccta ctccatcgct cgcaatatga
     7441 gtaaaagaaa agcctttacc atcatgtata ccctcttaat cctcggaatc ttcgtacctt
     7501 tccaagtcat catgattccg attacggtta tgatgagtaa actcggtttg gctaatacct
     7561 ttggtttgat cttgctctac ttgacctatg cgattccaca gaccctcttt ctctatgttg
     7621 gctatatcaa aatctcgatt ccagaaagtc tggatgaagc agcagagatc gatggggcta
     7681 atcaatttac aacctatttc cgcatcatct tcccaatgat gaaaccgatg catgcgacaa
     7741 ccatgatcat caatgccctt tggttctgga atgacttcat gttgccactc cttgtcttga
     7801 accgggattc caaaatgtgg actctgcctt tgttccaata caactacgca ggccaatatt
     7861 tcaacgacta cggaccaagc tttgcctctt acgtggtcgg cattatcagt atcaccattg
     7921 tctatctctt cttccaacgc catatcattt caggaatgag caacggggca gtgaagtaat
     7981 actcaatgaa aatcaaagag caaactagga agctagccgc aggttgctca aaacactgtt
     8041 ttgaggttgt ggatgaaact gacgaagtca gtaaccatac ctacggcaag gtgaagctga
     8101 cgtggtttga agagattttc gaagagtata agaagagctc atggaatcta tagtctttga
     8161 cacagaggaa gagtttagct tgttgataat tctatgcaga aaacaagaaa gtagtacttt
     8221 gtttatcaca gtctatatta gtacgagttt gatgataaat agagatttaa aatgaatttt
     8281 atttatgaag ccagatcata tgagacttgg cttcaattag aaaaaggaga gtaatgatgc
     8341 caattcaaaa taaaaccatg ttgattacct attctgatag ccttggaaat aatcttaaag
     8401 acttatatga taatttggaa gagcattttg gagatgctat tggaggagtt caccttttac
     8461 catttttccc atcaacaggt gatcgtggat ttgcgccagt tgactacgac gaagtggact
     8521 cagcttttgg tgattgggag gatgttaagc atttaggtga gaaatattat cttatgtttg
     8581 attttatgat taatcatatt tctcgtcaat ccaagtatta taaggactat caagaaaaac
     8641 atgaagccag tgaatttaaa gctctctttt taaactggga taagttttgg ccagaaaacc
     8701 gtccgacaca gtctgatgta gatttaattt acaagcgtaa ggatcgtgca ccaaagcaag
     8761 agattgtgtt tgaagatggt tcagtggaac atttgtggaa tacctttggt gaggagcaga
     8821 ttgatcttga tgtgaccaaa gaagtaacta tggaatttat ccgtaagacc attcagcact
     8881 tggcaagtaa tgggtgtgat ttgattcgtc tagatgcctt tgcttatgca gtgaagaaat
     8941 tggatactaa tgatttcttt gtggaaccag atatttggga tttattggac aaagttcgag
     9001 atatcgctgc tgagtatggg acagagcttt tacctgagat tcatgaacac tattcgattc
     9061 agtttaaaat agcagaccat gattactatg tttatgattt tgctcttcca atggtgacac
     9121 tttatactct ttacagttcc agaacagagc gtttggctaa gtggttaaag atgagcccga
     9181 tgaagcaatt tacgacgcta gatacccatg atgggattgg agtagtagat gtcaaggata
     9241 tcctgaccga tgaggagatt gactatgctt caaatgaact ctataaggtt ggagccaatg
     9301 tcaaacgtaa gtactctagt gccgagtata acaacttaga tatctaccaa atcaattcaa
     9361 cctactattc agcgcttgga gatgatgatg tcaagtattt tctcgctcgt ctaattcaag
     9421 cttttgcccc aggtattcct caggtttact atgtgggtct attagcaggc aagaatgact
     9481 tgaaattatt agaagaaact aaagaaggtc gaaatattaa tcgtcattac tatagcaacg
     9541 aggaaatagc aaaagaagtg caacgacctg ttgtgaaggc ccttctcaat ctattttctt
     9601 tccgtaaccg ttcagaagcc tttgatctag aagggactac tgagatagag acaccaacag
     9661 ctcacagcat tgtaatcaaa cgtcaaaata aagataagtc cgtaacagca gtagcagaaa
     9721 ttgatttgca aaatcagact tatcgggtaa ttgagaatgg agttgaagta acattttgaa
     9781 gccttgatat ggtggataaa atagggtttt tattttggaa aacgtttcct ttgttttcaa
     9841 attgctaaaa aagtggtaca atataggaca gcttactatt atctgaatca gctgatttgg
     9901 agagaaagga ttcattttga aatcaatagg ctttattgaa aagctgaagg ggttgtctag
     9961 taaagagctg attttattgg gaattatcct aagtatcttt ttaccctttt atctttttgt
    10021 agttgtactc tgtttatata ttatcagttt gatttttaca ggagacatga aaagtattct
    10081 tcagaaaatg ggggagcatc cgatgctgct tctttttctt agctatagta ctgttatatc
    10141 cattcttgca caaaattgga tgggtcttgt ggcttcagta ggaatgtttc tatttactat
    10201 tttctttttg cactatcagt cgattttatc ccataaattc tttcgattga ttttgcagtt
    10261 cgtcttgttt ggtagtgtct tgtcagctgc ttttgccagt ttagaacatt tccaaattgt
    10321 gaagaaattt aactatgctt ttctttcacc caatatgcag gtgtggcatc agaaccgggc
    10381 agaagtgacc ttctttaatc ctaattatta tggaattatt tgttgtttct gtattatgat
    10441 tgctttctat ctgtttacaa cgaccaagtt gaattggttg aaagtattct gtgtgattgc
    10501 aggctttgtt aatctctttg gtttgaactt tactcaaaat cgaactgcct ttcctgctat
    10561 tatcgctgga gcaattatct atctctttac gactattaaa aactggaagg ccttttggct
    10621 tagtattggg gtcttcgcga ttggtttgag tttcctcttt tctagtgatt tgggagttcg
    10681 aatgggtact ttagactctt ctatggaaga acgcatttct atctgggatg ctgggatggc
    10741 cttgtttaag caaaatcctt tttggggtga agggccattg acctatatgc actcttatcc
    10801 tcggatacat gctccttatc atgaacatgc ccacagtctt tatattgata cgattctgag
    10861 ttacggaatt gtgggtacca ttttattagt tttgtcttct gttgctcctg ttcgcttgat
    10921 gatggatatg agtcaggagt cggggaaacg tccgattatc ggcctttatc tatctttcct
    10981 tacagtggtt gctgtgcacg gaatttttga cttggctctc ttctggattc agtcaggctt
    11041 tattttcttg ctagttatgt gcagtattcc attggagcat cgaatgttgg tatcggacat
    11101 gacggattaa gttttataag tttgaaatct tctaccttgg gtaggagatt tttttatacg
    11161 atgggcatgt cgtgcatctg aggtgtaagt cctctgtagg gatccactac cggtgaatac
    11221 aatagcgctc cccaagcctg actatcgtga ggtagcggat taaaatggtc tggggataga
    11281 tcgttttaag tctgacgcag gaaataagaa ttgtcagaga aagcaatagt gaaatcgtag
    11341 gctatgaata gaaacgtgat agcgaggagc atatagtgga taaggtagcg agaaatttta
    11401 aagtataaaa gatagtctta atctatatat gtaaatcaca aaagtaattg aattcggaat
    11461 aaggttggtg tgaaaagaca tagtaaactg aatcttgaat actagaatga tacttctaca
    11521 atattgttat aatttaattt gaattccaaa atcacattgt ttcgtccgta tttcatttta
    11581 ctgtatgtct tcctaaactc caaagtttct gcgtcaaatt tcctattttc actgtagtct
    11641 ttgacacttc gaacgacaat ttgaatcata tattcaaaaa aaaatgaaaa atttgtgcca
    11701 acaagcctaa atattctgaa aatttgtttg atttttaatg gataatgtga tataatggtt
    11761 gtcaatctat aattcacata aacagaggag tagaaaatga aaaaaaatcg tgtatttgct
    11821 acagcaggtc ttgttttatt agcagcaggt gtacttgcag catgcagttc ttcaaaatca
    11881 tctgattcat cagcccctaa agcttatggc tatgtttata cagcagaccc agaaaccttg
    11941 gactacctga tttcaagtaa aaatagtaca acagtagtga cttcaaatgg gattgatggt
    12001 ttattcacta acgataatta cggtaatctt gctcctgcag ttgcagagga ttgggaagtc
    12061 tctaaggatg gtttgaccta cacttataag attcgtaaag gggttaaatg gtttacctct
    12121 gatggagaag aatatgcaga ggtgacggct aaagatttcg tgaacggttt aaaacacgca
    12181 gcagataaaa aatcagaagc tatgtattta gctgaaaatt cggttaaagg cttggcagat
    12241 tatctatcag gaacttcaac agatttttca acagttggtg tcaaggcggt tgatgattat
    12301 acgttacaat acactttgaa ccagcctgaa ccgttctgga actctaagtt gacctattct
    12361 attttctggc ctctgaatga agaattcgaa acatcaaaag gaagcgattt tgctaaacca
    12421 acagatccga catccttgct ttataatggt ccattcttgt tgaaagggtt gactgcaaaa
    12481 tcttctgtag agtttgtaaa aaatgagcaa tattgggata aagaaaatgt ccacctagat
    12541 actatcaatc tagcttacta tgatggatca gatcaggagt cgctagagcg taacttcact
    12601 agtggagctt atagttatgc ccgtctttac cctaccagct ccaactattc taaggttgca
    12661 gaagaataca aggacaatat ctattacaca caatcaggct ctgggattgc tggtctgggt
    12721 gtgaatattg atcgccaaag ttacaactat acttctaaaa ctacagattc agagaaagta
    12781 gctactaaga aggcattgct taacaaagat ttccgtcaag ccttgaattt tgctcttgat
    12841 cgctcagctt actcagctca aatcaatggt aaagatggag cagctttagc agttcgtaat
    12901 ttatttgtaa aaccagactt tgtttcagct ggtgagaaga cctttggtga tttagtcgct
    12961 gctcaacttc ctgcttatgg tgatgagtgg aaaggtgtga atttagctga tgggcaggat
    13021 ggtttattca atgctgacaa ggccaaggca gagtttgcga aagctaagaa agctttagaa
    13081 gcagacggcg ttcagtttcc tattcatctg gacgttccag tagaccaagc atcaaaaaac
    13141 tacatatctc gtattcagtc ctttaaacaa tctgtagaaa cagttcttgg tgttgaaaat
    13201 gtcgttgttg atattcaaca aatgacaagt gatgaattcc ttaatattac ttactatgct
    13261 gccaatgctt catctgagga ttgggatgta tcaggaggag tttcatgggg gccagactat
    13321 caagacccat ctacttacct ggatatttta aaaacaacta gcagtgaaac tacaaaaaca
    13381 tatttaggat ttgataatcc aaatagccct tcagtagttg aagttggttt gaaagaatac
    13441 gataaattag ttgatgaagc tgccagagag acaagcgact tgaatgtccg ttatgaaaaa
    13501 tatgcagcgg ctcaagcatg gttgacagat agttcactct ttattcctgc tatggcttct
    13561 tctggtgcag caccagtgct ttcacgaatt gttccattta ctggagcttc tgcgcaaaca
    13621 ggctctaagg ggtcagatgt ttacttcaaa tatttgaaat tacaagataa agtggtgact
    13681 aaggaagagt atgaaaaagc tcgtgaaaaa tggttgaaag aaaaagctga atcaaatgag
    13741 aaagctcaaa aagaattggc aagtcatgtg aagtaaataa tttctaatag aactttctct
    13801 ccatgaggag aaggttcttt tgggattttt aaaggaaata atatgaaaaa atatattttt
    13861 atgcgtgttt tgcggtcatt ggtttcgatt ttcttagtaa cgactttgac ctacacgatt
    13921 atctatacct tggttcctcg aaaattgatt ttcaagcagg atcctaacta taataaaatt
    13981 gcgacaacgg ctgataaacg tgataactat gaaaatactg tgtttgagcg tatgggctac
    14041 attgagtatt acgatactaa agagttgcaa gaaaaggcaa gtagcatgga ttcttctgta
    14101 acagtagaag caaatgcgac caataaagct atttatgaaa agtacatcaa tcaattaggt
    14161 catggttgga ctttgggaga atttactgaa agtggtcaat tctatgctac tcgtgaaatt
    14221 ccaatttttg aacgtgtttt tcacttctat gctaacttga ttgacattga ccatacaaat
    14281 aaaatccaag accctgaaaa tccagacttg aaacgctacc ttcgttttga aaatgatcca
    14341 gctatcggat ggtcattggt cggttcagga actaaacata aatatctctt gtactttaac
    14401 agtcagttcc catttgttca tcaaaacttt gtgaacttga atttaggtga ctcttaccca
    14461 acctatgcta atacaccagt tcttcaggtt attactcaag gtcaaggaca aaccaaaact
    14521 gcccaagttc agttcccaac aggtaagaaa acgtcttctg taaatattta ctcaagaacc
    14581 tacaagtcac ctagtcaggc tgactctcgt gaagtagcta gctatgggaa agatgatcct
    14641 tatacagcga ctgaaagtaa ttaccaatat ccatctatga ttgtcagctc tgctattact
    14701 ggtttgattg gtttggttct tgcctatgct cttgccgtgc cacttggttc agccatggct
    14761 cgtttcaaga acacttggat tgatagcctc tcaacagggg ctttgacctt cttgcttgct
    14821 cttccaacga ttgccttggt ttacatcgtt cgattgattg gatcatctat tgcccttcca
    14881 gattcattcc ctatcttggg agctggagat tggcgttctt acgttttacc agcagtcatc
    14941 cttggtttgt tgggtgctcc tggtacagcc atttggattc gtcgttacat gattgacttg
    15001 caatctcaag actttgttcg tttcgctcgt gcaaaaggtt tgtctgaaaa agaaatttca
    15061 aacaaacaca tctttaaaaa tgccatggtt ccgctggttt caggaattcc tggtgccatt
    15121 attggggtta tcggtggtgc aacccttact gaaacagtct tcgccttccc aggtatgggt
    15181 aaaatgttga ttgactctgt aaaagcatct aataactcta tggtcgttgg tcttgtcttc
    15241 atctttacat gtatttctat cttctcacgt cttttgggag atatttggat gactattatt
    15301 gacccacgta ttaaattgac tgagaaagga ggcaaataat gtctacaatc gataaagaaa
    15361 aatttcagtt tgtaaaacgt gacgattttg cctctgaaac tattgatgcg ccagcatatt
    15421 cttactggaa atcagtgttt aaacaattta tgaagaaaaa atcaactgta gtcatgttgg
    15481 gaatcttggt agccatcatt ttgataagtt tcatctaccc aatgttttct aagtttgatt
    15541 tcaatgatgt cagcaaggta aacgacttta gtgttcgtta tatcaagcca aatgcggagc
    15601 attggttcgg tactgacagt aacggtaaat cgctctttga cggtgtctgg ttcggagctc
    15661 gtaactccat cctcatttct gtgattgcga cagtgattaa cttggttatc ggtgtttttg
    15721 tcggtggtat ttggggtatt tcaaaatcag ttgaccgtgt catgatggaa gtttacaacg
    15781 tcatctcaaa catcccacct cttttgattg ttattgtctt gacttactca atcggagctg
    15841 gattctggaa tctgattttt gccatgagcg taacaacatg gattggtatt gccttcatga
    15901 tccgtgtgca aatcttgcgc tatcgtgact tggaatacaa cttggcgtca cgtactttgg
    15961 gaacaccaac cttgaagatt gttgccaaaa atatcatgcc tcaattggta tctgttattg
    16021 tgacaaccat gactcaaatg cttccaagct ttatctcata cgaagccttc ttgtctttct
    16081 tcggtcttgg attaccgatt acagtgccaa gtttgggtcg tttgatttcg gattattcac
    16141 aaaacgtaac aaccaatgct tacttgttct ggattccatt gacaaccctt gtcttggtat
    16201 ccttgtccct tttcgtagtt ggtcaaaact tagcggatgc tagtgatcca cgtacacata
    16261 gataggagta gaaatgacaa aagaaaaaaa tgtaattttg actgctcgcg atattgtcgt
    16321 ggaatttgac gttcgtgaca aagtattgac agccattcgc ggcgtttccc ttgaactagt
    16381 cgaaggagaa gtattagcct tggtaggtga gtcaggatca ggtaaatctg ttttgacaaa
    16441 gaccttcaca ggtatgctcg aagaaaatgg tcgcattgcc caaggtagta ttgactaccg
    16501 tggtcaggac ttgacagctt tatcttctca caaggattgg gaacaaattc gtggtgctaa
    16561 gattgcgact atcttccagg acccaatgac tagtttggac cccattaaaa caattggtag
    16621 tcagattaca gaagttattg taaaacacca aggaaaaaca gctaaagaag cgaaagaatt
    16681 ggccattgac tacatgaata aggttggcat tccagacgca gatagacgtt ttaatgaata
    16741 cccattccaa tattctggag gaatgcgtca acgtatcgtt attgcgattg cccttgcctg
    16801 ccgacctgat gtcttgatct gtgatgagcc aacaactgcc ttggatgtaa ctattcaagc
    16861 tcagattatt gatttgctaa aatctttaca aaacgagtat catttcacaa caatctttat
    16921 tacccacgac cttggtgtgg tggcaagtat tgcggataag gtagcggtta tgtatgcagg
    16981 agaaatcgtt gagtatggaa cggttgagga agtcttctat gaccctcgcc atccatatac
    17041 atggagtctc ttgtctagct tgcctcagct tgctgatgat aaaggggatc tttactcaat
    17101 cccaggaaca cctccgtcac tttatactga cctgaaaggg gatgcttttg ccttgcgttc
    17161 tgactacgca atgcagattg acttcgaaca aaaagctcct caattctcag tatcagagac
    17221 acattgggct aaaacttggc ttcttcatga ggatgctcca aaagtagaaa aaccagctgt
    17281 gattgcaaat ctccatgata agatccgtga aaaaatggga tttgcccatc tggctgacta
    17341 ggaggaagga aatgtctgaa aaattagtag aaatcaaaga tttagaaatt tccttcggtg
    17401 aaggaagtaa gaagtttgtc gcggttaaaa atgctaactt ctttatcaac aagggagaaa
    17461 ctttctcgct tgtaggtgag tccggtagtg ggaaaacaac tattggtcgt gctatcatcg
    17521 gtctaaatga tacaagtaat ggagatatca tttttgatgg tcaaaagatt aatggtaaga
    17581 aatcgcgtga acaagctgcg gaattgattc gtcgaatcca gatgattttc caagaccctg
    17641 ccgcaagttt gaatgaacgt gcgactgttg attatattat ttctgaaggt ctttacaatc
    17701 accgtttatt taaggatgaa gaagaacgta aagagaaagt tcaaagtatt atccgtgaag
    17761 taggtcttct tgctgagcac ttgactcgtt accctcatga attctcaggc ggtcaacgtc
    17821 aacgtatcgg tattgcccgt gccttggtca tgcaaccaga ctttgttatt gcagatgagc
    17881 caatttcagc cttggacgtt tctgtacgtg cccaagtctt gaacttgctc aaaaaattcc
    17941 aaaaagagct cggcttgacc tatctcttca tcgctcatga cttgtcggtt gttcgcttta
    18001 tttcagatcg tatcgcagtt atttacaagg gtgttattgt agaggttgca gaaacagaag
    18061 aattgtttaa caatccaatt cacccatata ctcaagcctt gctttcagca gtaccaatcc
    18121 cagatccaat cttggaacgt aagaaggtct tgaaggttta cgacccaagt caacacgact
    18181 atgagactga taagccatct atggtagaaa tccgtccagg tcactatgtt tgggcgaacc
    18241 aagccgaatt ggcacgttat caaaaaggac taaactaata atggttttat aatttccatg
    18301 tcaattttta tgggaattat aaaacttttt ttgttggact gatttgaaaa actttgaaag
    18361 cttcctgaaa gaattttcga aaaattttaa aaaattttga aatattattg acaggtgatg
    18421 aaaaaggtgg taggatagga aggatcaaaa aagaaagcag aaaaagaaat gaataagaga
    18481 caagccgtaa ctatgaatca aaacttttac tttagctact ttagatagtg tttgtagaca
    18541 tgtcaccatg gatgcaaaca gttcaagcaa tttgtttgta tctatgtggc taagattttt
    18601 gattgtggtc catatagatg aatatctaaa tggactagct aagttgtaac ttgttaggtt
    18661 atttcaagta cccgtttaga tagtatctag gcggtttttt gttttatctt ttctgagaag
    18721 gagtttcatt atgaaagttg ttcgaaaatc actagccccc tcttggtagt ggggatcctc
    18781 ttgacttctc tgatcagttt gcatcagttg aaggcagata agaaaagaga tgtctttcgt
    18841 atcggtattt cgcagtttat tacccaccag tccttagacg ctactagaga aggatttgtg
    18901 gatgagctgg ccaaacaagg ctatgttgag ggggaaaata ttgagattga tttgcaaaat
    18961 gcacagggag aacaaagaaa tctaaaaacg atttcccagc aactagcaga atccagcgat
    19021 gtcgttctag ccatcgcaag gccttctgct cagagcttgg ccaatacgac gcaaacgcca
    19081 ccagttatct tttcagctgt aacagaccca gtcagtgcca agttggttga gtcaagagaa
    19141 catcctgggg gcaatgtaac tgggacaagc gatcagtcat cagatgccat ttcaacccaa
    19201 atcaatttga taaagaaagt gttgccaaag gctaaaacga ttggaatcct ctatactcag
    19261 agcgagccca attcggttgt ttaaaatgat gaagctaagc gacttctgaa agaaaaaggc
    19321 tttaccgttg ttgaaaaaac aatcttggac agtaataacg tcaaggcggc agcagagagt
    19381 ttgatggcag aggtggatat ggtttttgtc ccaactgata atatcatttc gtcaaccatg
    19441 gaaacagtta agcaggtttc tattaaacac aaggttccag tattcggtgg ttcaacagaa
    19501 atgattgctg ttggtgactt gtataactac ggaaccaatt atgaagaatt gggaagacag
    19561 acagctcgca tgctgattcg tgttttaaaa ggtgagaaac cagaaaatat agcagttgag
    19621 ttgcctgaaa aactggaatt gcataccaat caagaaatgg cagatgcatt gggaattgat
    19681 attagtaagt tagaaggcaa ggaataagga ggattaagat gaattttgtg ttatctagtt
    19741 tatcagaagg tttgttgtgg tcgattgtgg cgattggggt ctacttgact ttccgtattt
    19801 tggatattgc ggatataact gctgagggag cctttcctct gggggcagca gtcgttgtat
    19861 cacagataca ggcaggggca aatccttggc ttgcgacttt acttgctttg ctggcaggta
    19921 tggtagcagg tcttgtatca ggaatgctcc acaccaagat gaaaatccca gctctcttga
    19981 cagggattgt gaccttgaca gggctctatt caatcaatat taaaattatg ggcagtgtac
    20041 ccaatctttc cttgggagat tctgcaaccg tctttaaaca gttggcgagc ttgggtctga
    20101 caaatgaagg agctgttttc tcacttagtt tagtctgtct cttacttgtt tggtcttgac
    20161 ccttttgatg aaaacagaga ttggtttggt cttgcgttcg actggggata atatcccgat
    20221 aagtgaggcc aatggagtca atgtagacac catgaagatt gttggttaca tgatttcaaa
    20281 cggtttgatt gccctatgtg gttccttgtt tgcccaaaat gatggatttt cagatgtgac
    20341 ttctgggaca ggaaccattg ttgttggttt gagctcggaa gtcttgatac acgacttgac
    20401 cattggaggc cgcttattat ccatcggaat cggtgctatt gtttaccgtt tgattatttt
    20461 aaatatctat gaaattccaa atctagatca aaacttggta cgtctcttta atgcaatctt
    20521 gctcgctttg gttttatttg caccagaatt gcaaaagaga ttaaagattc gtggtctgaa
    20581 attgagaaat gaataggagg agaaagttat ggcaagtttg ttaacacttg aaaatattca
    20641 caagacattt gaagcaggga cggtcaatga gaaccatgtc ctcaaaggat tagatttaga
    20701 ggttgaagag ggagatttta tctatgtgat tggtggaaat ggagcaggaa aatccacttt
    20761 gatgaatatc ttggctggca atctatcggt ggacgaaggg gaccttctac tggcagggaa
    20821 atccattaaa aatctgagtg tcagaaagag agccaaggat attgcccgtg tttttcaata
    20881 tcctaagatg ggaacagctt ctcgtttgac gattgaggag aatatggcta ttgccttgag
    20941 acgtgggcaa aagagagggc ttggttgggg tgtgaaggag aaggatagaa tccagttcca
    21001 agaggccttg aaggagttga atattggtct tgaaaaccgc ttaaaagtag atactcaata
    21061 tctctcagga ggacaaagac aggctttgac cctagtcatg gcagctctgg tgaaacccaa
    21121 acttttactt ttggatgaac atactgcggc acttgacccg aaaaccagtc aaatggtgat
    21181 ggacttgacg caaaagattg tggagcacca tcagtggacg actttgatga ttacccatga
    21241 tatgaatcat gcgattgagt acggcaatcg tctcattatg ctctatcaag gcaagatagt
    21301 ggtggatgtc aagggagaag agaaaaagca tctgacagtt gaagacctta tgcatctctt
    21361 ccagaaaaat agtggccaaa gtctggtcag tgatgaatta gttttgggat aaagaaaaag
    21421 gctgagatct ggtgtctcag tcttttattt cttgcgtttt gcaaaatcta caaatctaaa
    21481 tttttctaac ttatggcgac tttcggtaaa ctgaaattgg cgtccgtctt ggagatagac
    21541 ttttgattta atcgaaacga cataagggtc tttgccaatg tccatgagaa tcttgtctcg
    21601 gtcgcttgag tggtcaatgg tgatttcctt ctgagcataa tcaataagga gtttgaggcc
    21661 attttctata taagaataga tagactgctc agcaatttgg cgagtgagat ttggaattag
    21721 ttccatatcc agatagtctg tatccagaac ggataccaga tcatccacca cacgctggcg
    21781 gaccaccttc caaaccatcc gaaactctgg gaaaccggtt atcagtgagg attttttatc
    21841 aataataatc ttgtccagac tgaccacgtt ggttttagag cgcagtccaa gttctttaac
    21901 tagttcttgg tagctggtta ggttggatac agggaaattg acggtttctt ctttgacgac
    21961 ttgagaacct tgccctctta tctttttgat caatccttcc tcttggagga gagacagggc
    22021 ctttcggacg gtatcacgac tcacttgata ttgctccata aggtcgtgct cgctaggaag
    22081 gaaatctccg acagcgtaag tctcgttttg aatggtttct tggatttgct taaataattg
    22141 ttggtatttc ttcattttgc ctgcttaaat aggtttttag tctagtttaa tgaacacctg
    22201 tatctatttt accatacaag tgctagaaaa tttacaaaaa aacacccttt ttataccaaa
    22261 caagttgcag acaagtttgg tatcgtttac aatatactta tcaaatcaaa cttgctttga
    22321 caagtataag gagaatcaaa tgggaaaatt tgaacaagaa gccaaagatc tgcttcaggc
    22381 aattggaggc aaagaaaatg tgactgccgt aactcactgt gcgacacgga tgcgctttgt
    22441 tttaggagat gataagaagg ctaatgttaa agctatcgag tcaattccag ctgttaaagg
    22501 aacttttaca aatgcaggtc aatttcaggt aatcattgga aatgacgtgc ccatctttta
    22561 taatgatttt acagccgttt caggtattga gggtgtttcc aaagaagcag ccaagtctgc
    22621 agctaagagt aatcaaaacg tggtccaacg tgttatgacc actctggcgg agatttttac
    22681 tccgattatt ccagccttga tagtcggagg attgatcctc ggtttccgta atgtcttgga
    22741 aggtgtccat tggtcgatgt tggatggcaa gaccatcaca gaatcctctc agttttgggc
    22801 aggtgtcaat cacttcctct ggttgcctgg tgaagctatc ttccagttct taccagtagg
    22861 gattacttgg tctgtttctc gtaagatggg aaccagccaa attttgggaa ttgttctcgg
    22921 aatctgtttg gtatcgcctc agttgctcaa tgcctatgcg gttgcttcaa cgccagcagc
    22981 tgatatcgcg gcaaactggg tttggaattt tggctatttt actgttaatc gtatcggtta
    23041 ccaagcccaa gttatcccag ccttgcttgc aggtttgagt ctgtcttatc ttgaaatctt
    23101 ctggcgcaag catatcccag aagtcatttc tatgattttt gtacctttct tgtcattgat
    23161 tccagccttg attttggctc atactgtttt gggaccaatc ggttggacaa ttggacaagg
    23221 gctttcatca gttgtcttgg caggtttaac tggtccagtt aaatggctct tcggtgcaat
    23281 ttttggtgcc ctctacgctc catttgtcat cacaggtctg caccatatga ccaatgccat
    23341 tgatacacaa ttgattgcgg atgctggtgg cactgcccta tggccaatga ttgctctttc
    23401 taatattgct caaggctcag ccgtgtttgc ctattatttc atgcatcgcc atgatgagcg
    23461 tgaggctcag gtttcacttc ctgcaaccat ttcagcctat ctcggtgtta cagaaccagc
    23521 tctttttggg gttaacgtaa aatatattta tccatttgtt gctgggatga ctggttcagc
    23581 ccttgcaggc atgttatccg ttacttttaa tgtaactgcg gcttctattg gtatcggtgg
    23641 tttgccaggt attctctcta ttcaacctca atacatgctg ccatttgcag gaactatgct
    23701 agttgcgatt gttgttccaa tgctcttgac tttcttcttc cgcaaggctg gtctctttac
    23761 aaaaacagag ggcgatacga acttgcaggc agaattcgtt gctcaagaag aagcagaatt
    23821 tgtgaaccat gaaccagtag aacttacttc ggtagaaatt atcagcccac taactggcca
    23881 agtgaaagaa ttgagtcaag cgacggatcc tatttttgca tcaggtgtca tggggcaagg
    23941 tctagtcatt gaaccaagcc aaggtgagtt gacctctcca gttaatggga cagtgacggt
    24001 tcttttccct accaagcatg ccatcggcat tgtctctgac gagggagttg aattgctcat
    24061 ccacatcggt atggatacag taggtcttga tggcaaaggt tttgaaagtc ttgtagtcca
    24121 aggagatcac gttacagttg gtcagcaact gattcgtttt gatatggatg tcattaaggc
    24181 tgcaggtctg gtgacagaaa ctcctgttat catcaccaac caagatgctt atacagcgac
    24241 tattcccgga acttatccga caacgatcca agctggagca tctctcatgg tcgctacacg
    24301 aatctaatac tcttcgaaaa tctcttcaaa ccacgtcagc tctatctgca acctcaaaat
    24361 agtgttttga gcaacctgtg gctagcttcc tagtttgttc tttgattttc attgagtata
    24421 attgaaatag cacaaatagg gacggaagac tgcttcctcc cttttatcag aaaaggagaa
    24481 acagatgaca cttgataaag gaaaagtagt ctatcaaatc tatccaaaat cttacaaaga
    24541 caccactgaa aacggtattg gggatttccg tgggattatc ggaaaaattc cctatctagc
    24601 caaactaggt gtggatatgg tctggctcaa tccattctat ccaagtcctc aacgggataa
    24661 tggttacgat atttcagatt atatggcagt ggatcctctt tttggtgata tggctgattt
    24721 tgaggaaatg gtgtgtatcg gtaaagagca caagattgac tttatgctgg acatggtact
    24781 taatcattgt tcgacagagc atgaatggtt tcagaaagcc ctagctggtg ataagtatta
    24841 tcaagacttt ttcttcatcc aagaccaacc aacagattgg cagtctaagt ttggtggttc
    24901 tgcatgggcg cctttcgggg atactgggaa atactatctt cacctatttg atgagaccca
    24961 ggctgacctt aactggcgca atcccaatgt ccgtaaggag cttttcaagg ttgttaattt
    25021 ctggcgcgac aagggtgtca aaggttttcg atttgatgtg atcaatttga ttggtaagga
    25081 cgaggtttca gtggactgtc ctgaaaatga agggaagcca gcttatacag acaaacccat
    25141 cgttcataac tatttgcgta tgatgaacca agccactttt ggatctgacg atagctttat
    25201 gacagttggg gaaatgtctt ctaccaccat ggaaaactgt gtcctctatt cgtcgcctga
    25261 tcgtcaggaa ttatccatga cctttaattt tcatcacctc aaggtggact ataaggatgg
    25321 acaaaagtgg accttggctc cctttgattt tgaagagttg aagagtcttt accatagttg
    25381 gggtaaggaa atgagtgata aagacggttg gagtgccctc ttttggaaca atcacgatca
    25441 accacgtgcc ttgaaccgtt ttgtcgatat tcaaaacttc cgcaaggaag gagccaccat
    25501 gctagcagcc agcattcacc tgtcacgtgg gacaccttat atctacatgg gtgaggaaat
    25561 cgggatgatt gacccagact atgattctat ggctgattat gtggatgtcg aatcgcttaa
    25621 tgcctatcag atgctcttag aagaaggaaa gagtcagcaa gaagccttcc agattattca
    25681 agctaagtcg cgtgataatt cacgcattcc catgcagtgg gatgcttcgg aaaatgcagg
    25741 attttcaaca ggcactcctt ggttgaaagc tggtaaatcc tataaataca tcaatgtaga
    25801 aaatgaaatc cagggtccga tttttacctt ctatcaagac ttgattcgac tgcgtaagga
    25861 aatgccaatc atttcagaag gaagttacaa accagccttt gaagatagca aacaagtcta
    25921 cgcttttgaa cgccagtttg aggatcaaaa gttactagtg ctcaataact tttatgctaa
    25981 agaagtggaa atcgacttgc cagcagtcta ccaaaatgga cagattttga tttcaaacta
    26041 tgaagatgca gaagtgtctg agaaaattct actaaaaccc tatcaaacac tggctattta
    26101 tgtaaattaa acttagcaag gagacctctt tttcagaaaa gcaggtcttt ttttgctgtc
    26161 tattccatcc ttgaaagtgt agaacaaact ggtcagggtg gctagtttgt ggtataatga
    26221 aagggactca aaaagaaaca ggagaaaaat gatggattta cttttagcaa ttgtattgat
    26281 tgtgctagct tttctaggag gagctcttgg aggaatgtac ttggttcgta agcaaatcga
    26341 aaaagaattt gctgacaacc cacgtttgaa tgctgaagca gttcgtactc ttttgagtgc
    26401 aaatggtcaa aaaccaagcg aagctaaggt acaacaagtt taccaccaaa tcatccgcca
    26461 acaaaaggca gcccttgcta acaataaaaa gaaaaaataa ataaggaaaa gtctgggatg
    26521 aaagttccag acttctcact atgttggtta tggtttaggg atgagacttt ttccttgcat
    26581 tctattgata tttgattatg attaagagag aggtagttga cattctatca agctgtcggt
    26641 cagttcgttc agtacaagga atcataatga acgatcaatc agaaaaaaga ctagaaagaa
    26701 gactgtatgg ataatcgacc aattggtttt ttggattcgg gtgtcggggg cttgaccgtt
    26761 gtgcgcgagc tcatgcgcca gcttccccat gaagaaatcg tctatattgg agattcggcg
    26821 cgggcgccct atggcccccg tcctgctgag caaattcgtg aatatacttg gcagctggtc
    26881 aactttctct tgaccaagga tgtcaaaatg attgtcattg cttgtaacac tgcgactgcg
    26941 gtcgtctggg aagaaatcaa ggctcaacta gatattcctg tcttgggtgt aattttgcca
    27001 ggagcttcgg cagccatcaa gtccagtcaa ggtgggaaaa tcggagtgat tggaacgccc
    27061 atgacggtac aatcagacat ataccgtcag aaaatccatg atctggatcc cgacttacag
    27121 gtggagagct tggcctgtcc caagtttgct cccttggttg agtcaggtgc cctgtcaacc
    27181 agtgttacca agaaggtggt ctatgaaacc ctgcgtccct tggttggaaa ggtggatagc
    27241 ctgattttgg gctgtactca ttatccactc cttcgcccta ttatccaaaa tgtgatgggg
    27301 ccaaaggttc agctcatcga tagtggggca gagtgcgtac gggatatctc agtcttactc
    27361 aattattttg aaatcaatcg tggtcgcgat gctggaccac tccatcaccg tttttacaca
    27421 acagccagta gccaaagttt tgcacaaatt ggtgaagaat ggctggaaaa agagattcat
    27481 gtggagcatg tagaattatg acaaataaaa tttatgaata taaggatgac caggactggt
    27541 atgttgggtc ttatagtatt tttggtggcg ttaacagttt gagcgactat cagacagatt
    27601 ttcctctgtt tgaattctcc aaaatatttg gagatgaaga gtatggtttc ccgctttcag
    27661 ttactgtttt acgctatggt tctacctacc gtttgttctc ctttgtggta gatatgctta
    27721 atcaagaaat gggacgaaac ttggaagtta ttcaacgtca tggggccctg ctcttggttg
    27781 aaaatgggca actcttgtat gtagaattgc ctaaagaagg ggtcaatgtt catgatttct
    27841 ttgagacaag caaggtcaga gaaaccttgt tgattgcgac tcgtaacgaa ggcaaaacca
    27901 aggaattccg agctatcttt gataagttag gctacgatgt ggaaaatctt aatgactacc
    27961 ctgacctgcc tgaagtagca gaaacaggta tgacctttga agaaaatgcc cgccttaagg
    28021 cagaaaccat ttctcaatta acgggtaaga tggttttggc agatgattct ggtctcaaag
    28081 tcgatgtcct tggtggctta ccaggcgtct ggtcagctcg tttcgcaggt gtgggagcaa
    28141 ctgaccgtga aaataatgcc aaactcttgc acgaattggc catggtcttt gaactcaagg
    28201 accgctcggc tcagttccac acaaccctag tcgtagccag cccaaataag gaaagtttag
    28261 ttgttgaagc agactggtca ggttatatta actttgaacc taagggtgaa aatggctttg
    28321 gctatgatcc cctcttcctt gtaggagaga caggtgagtc atcagctgaa ttaaccctgg
    28381 aagaaaaaaa tagtcaatct caccgtgcct tagccgttaa gaaacttttg gaggtatttc
    28441 catcatggca aagcaaacca tcattgtaat gagcgattcc catggcgata gcttgattgt
    28501 ggaagaagtc cgtgatcgct atgtgggcaa agtcgatgcc gtttttcata acggcgattc
    28561 tgaactacgt ccggattctc cactttggga gggcatccgc gttgttaaag ggaacatgga
    28621 cttctacgcc ggctacccag aacgtctggt gactgagctt ggttcgacca agattatcca
    28681 aactcatggt cacttgtttg acatcaattt caactttcaa aagttggact actgggctca
    28741 ggaggaagag gccgctatct gcctctatgg tcacttgcat gtgccaagtg cttggatgga
    28801 aggcaagatc ctctttctaa atccaggttc tatcagccaa ccacgaggta ccatcagaga
    28861 atgtctctat gctcgtgtgg agattgatga tagttacttc aaagtggact ttttgacacg
    28921 agatcacgag gtgtatccag gtttgtccaa ggagtttagc cgatgattgc caaggagttt
    28981 gagactttct tgttggggca ggaggaaact tttttgaccc ctgctaaaaa tctagctgtg
    29041 ttgattgata cccacaatgc ggatcatgcg accctcttgc ttagtcagat gacctatacc
    29101 cgtgttcccg ttgtgacaga tgaaaaacag tttgttggga cgattggact cagagatatt
    29161 atggcttatc agatggagca tgacttgagc caagaaatca tggcggatac ggatatcgtt
    29221 catatgacaa aaacggacgt agcggttgtt tcgcctgatt tcaccattac ggaggtcttg
    29281 cacaagctag tagatgagtc cttcttaccg gttgtggata cagagggtat tttccaaggg
    29341 attattacgc gcaagtccat cctcaaggcc gttaatgccc tcttgcatga ttttagtaag
    29401 gaatatgaga ttcgatgcca atgagagaca gaatttcagc ctttttagag gaaaagcagg
    29461 gcttgtctgt caattccaag cagtcctata agtatgattt ggagcaattt ttagacatgg
    29521 taggtgagcg gatttctgag accagtctca agatttacca agcccagcta gccaatctaa
    29581 aaatcagcgc ccagaagcga aagatttcgg cctgtaacca atttctatac tttctctatc
    29641 aaaaaggaga ggtggacagc ttttaccgct tggaattagc caaacaagct gaaaagaaga
    29701 cggaaaagcc agagattcta tacctagact ctttttggca ggaaagcgac catccagagg
    29761 gccgcttgct agcgctctta atcctagaaa tggggctctt gcccagtgag attttagcca
    29821 tcaaggttgc ggacatcaat ctggattttc aggtgctgcg aatcagcaag gcttcccaac
    29881 agaggattgt caccattccc acggccttgc tttcagaatt ggaacccttg atggggcaga
    29941 cctatctttt tgaaagagga gggaaaccct attctcgtca gtgggccttt cgtcagttag
    30001 aatcttttgt caaggagaaa ggttttccat ccttatcagc tcaagtctta cgtgaacagt
    30061 ttattctaag acaaatagaa aacaaggtcg atttgtacga aattgcaaaa aaattaggat
    30121 taaaaacagt cctgacctta gaaaaatata gataatggat attaaattaa aagattttga
    30181 aggacccctg gacttactct tgcatctggt ttctaagtac cagatggata tctacgatgt
    30241 gcccattacg gaagtcatcg aacagtatct agcctatgtc tcaaccctgc aggccatgcg
    30301 tctggaagtg acgggtgagt acatggtcat ggctagtcag ctcatgctga ttaagagtcg
    30361 taaactcctt ccgaaggtag cagaagtgac agacttgggg gatgacctgg agcaggacct
    30421 cctctctcaa atcgaagaat atcgcaagtt caagctcttg ggtgagcact tggaagccaa
    30481 gcaccaagaa cgggcccagt attattccaa agcgccgaca gagttgattt acgaagatgc
    30541 ggagcttgtg catgacaaga cgaccattga cctctttttg gctttttcaa atatcctagc
    30601 caagaaaaaa gaggagtttg cacaaaatca cacgacgatc ttgcgggatg agtataagat
    30661 tgaggacatg atgattatcg tgaaagagtc cttgattgga cgagatcaat tgcgcttgca
    30721 ggatttgttc aaggaagccc agaatgtcca agaggtcatc accctctttt tggcaaccct
    30781 agagttaatc aaaacccagg agctgatcct cgtgcaagag gagagttttg gagatatcta
    30841 tctcatggaa aagaaggaag aaagtcaagt gcctcaaagc tagacttgat agagaggaaa
    30901 gatgagtact ttagcaaaaa tagaagcgct cttgtttgta gcgggtgaag atgggattcg
    30961 ggtccgccag ttagctgaac tcctctctct accaccgaca ggcatccagc aaagtttagg
    31021 aaaattagcc cagaagtatg aaaaggaccc agattccagt ttggctttga ttgagacaag
    31081 tggtgcttat agattggtga ccaagcctca atttgcagag attttgaagg aatactctaa
    31141 ggcgcctatc aaccagagct tgtctcgggc tgcccttgag accttgtcca ttattgccta
    31201 caaacagccg attacgcgga tagaaattga tgccatccgt ggagttaact cgagtggagc
    31261 cttggcaaag ttgcaggctt ttgacctgat aaaggaagac gggaaaaagg aagtattggg
    31321 gcgccccaac ctctatgtga ctacggatta tttcctagat tacatgggga taaaccattt
    31381 agaagaatta ccagtgattg atgagcttga gattcaagcc caagaaagcc aattatttgg
    31441 tgaaaggata gaagaagatg agaatcaata agtatattgc ccacgcaggt gtggccagta
    31501 ggagaaaagc agaagagctg attaagcaag gcttggtgac ggttaacggc caagtggtgc
    31561 gtgaactagc aaccactatc aagtcaggcg acaaggtcga agttgaaggt caacctatct
    31621 acaacgaaga aaaggtctac tatctgctta acaaaccacg cggtgtgatt tccagtgtga
    31681 cagatgataa gggtcgcaag acggttgtcg acctcttgcc caatgtcaaa gagcgtattt
    31741 accctgtggg tcgtttggac tgggatacat caggagtctt gattttgacc aatgatgggg
    31801 actttacaga cgagatgatt caccctcgta atgagattga caaggtttat gtcgcgcgtg
    31861 ttaaaggtgt ggccaataag gacaatctcc gccccttgac ccgtggtctt gagattgatg
    31921 gtaagaaaac caagccagct gtttatgaaa ttctcaaagt ggacccagtc aaaaatcgct
    31981 ctgtggtgca gttgatcatc catgaagggc gtaaccatca ggttaaaaag atgtttgaag
    32041 ctgttggtct ccaagtagat aagttgtctc ggactcgttt tggacaccta gacttgacag
    32101 gactccgtcc aggagaatcc cgtcgtctta ataaaaaaga aatcagccaa ctacacacca
    32161 tggctgtaac taagaaataa tgaaacgaat tttaatagcg cctgtgcgct tttaccaacg
    32221 ttttatctca ccagtctttc caccctcttg tcgctttgag ctgacttgtt ccaactacat
    32281 gattcaggct attgaaaaac atggttttaa gggggtattg atgggcttgt ctcggatttt
    32341 acgttgtcat ccctggtcga aaacaggtaa ggaccccgtt ccagaccgct tttcccttaa
    32401 acgaaatcaa gaaggggaat gaggtggggt aaatagattt caaaatgata aaaacgcatc
    32461 ctatcaggtt tgagtgaact tgataggatg cgttttagaa tgtcaaaatt ttatactctt
    32521 cgaaaatctc ttcaaaccgc gtcagctttc atctgcaacc tcaaaacagt gttttgagca
    32581 acctgcggct agttttctag tttgctcttt gattttcatt gagtattaaa ttgagtttga
    32641 agtggcttat ttcaaagctt tttgtatgtc ttcaatcatg agttttgttg attcaagtcc
    32701 gcctccgctt agataccaga ggtctggtgt tagttggata atcttaccat ttttagcagc
    32761 aggtgtttca gcgataaggg cattttctag gacaccgtcg ttgctagagt tgtccccacc
    32821 gatggcaagg gtacggttga tgacaaagag gatgtcaggg ttgatttctt tgacactttc
    32881 aaagctgact tcttgtccgt ggcgtgagtc ttcaaatgtt gtatcagttg gtttgaattt
    32941 caaggtttgg tacaagaaag agaaacgaga tttggcacca aaggctgcca tttttccttc
    33001 attaaggagg atcgcaaggg cttttttgtc agagctttca tttttagtag cgacttcttg
    33061 gatgctcttg tctagcttgg ccaattcttc cttggctttc tgtgtaccag tttcgccgaa
    33121 ggcacttgct aaggattcga tattagcctt ggtagaagtc cagtagtcgt ccttgcttgc
    33181 ttggaagaga acggttgggg cgatttcttt gaatttgtct acgaattttt gtgtacgtgg
    33241 tgaagcgata atcaaatcag gctcaagggc ggcgatagct tctaaatcag gttctttcat
    33301 agaaccaaca tttttgacag ttcccactag gtcttttaga taagtcggaa cagtttttgt
    33361 aggcattccg acgatatttt tttcaaatcc taaagcgcga atagtatccg cagcgccgag
    33421 gtcaaaggtc acaatctttt caggaacttt ggaaagtttg acctcgtcca gtgaactttt
    33481 aatggttacc tctgttggag cagagctact ggtctctgtc tgactagtgc ttgagtttgt
    33541 actacatgca ccaagtagga gcaagaagct ggccactagg gcagtgaaat aaagtttaag
    33601 ggatgttttc ataatttctc ctttttaaaa tgtgataacg atttagggag tctcttaatc
    33661 ttattgacta agagactgaa ggttctctaa cttgagcttt tatgttacta gctatagata
    33721 cagatctttt tgttattgat atcagctagc gtgatgggaa tctcataaag ttgactgagc
    33781 aggtcagcct gcatgatttg atcggttctt cccttgctaa agacctggcc gtccttgaag
    33841 gcgacaattt catctgcata ctgactggcc atgttgatat cgtggaggac gatgataatg
    33901 gtcttgccga gttcctccac cagtcgtcga agaatctgca tcatgctgac gctttgcttg
    33961 atatcgagat tgttgagtgg ttcgtccagc aagataaagt ccgtatcctg ggccagtacc
    34021 atagcgataa agacgcgctg gagttgcccc cctgacaggc tattgatgta gcggtctttt
    34081 aagttggtca gttccaaata gttcagagtt tctcggattt tttcccagtc ttctgatcta
    34141 agtcgacctc ggctgtaggg aaaacgtcca aaactgacca gttcttcaac agtcaatttg
    34201 gcttggtaat tgattttctg ttttaggatg gttagttctt gggccagttc ttgcgaattc
    34261 cagctctcga tttcacgtcc tttgatactg agaactccct gatctttctt ggttagtctg
    34321 ctcatgatgg agaggagagt cgattttcca gcaccatttg gaccaataaa ggctgtcagt
    34381 ttttgaggac tgacttcaag cgaaatgcct tgcaaaatat cctgtttttg aatggatttg
    34441 tcaatgtttt ccagtttcac tgacgagccc tcctatatag taagataaag aataagaagc
    34501 cacccacact ctcaatgatc atactgatac gaatttccag tgcaaagact cgttcaatca
    34561 aggcttgccc caaggttaag ctaataaatc caaccagaat ggccactata aagagtaact
    34621 tgtgctgata gtctttgaca atcaggtagg tgaggttggc cagcataaag ccgaagaagg
    34681 ccataggtcc taccaaggca gtggccgttg aggtcaaaag cacgattccc cagaggagct
    34741 ctttctgttc tttttcaaca tcgagtccca atatctgagc cgtttctctt tgcaggtgca
    34801 agacatctag aacgactgct tttcgaaaga aaaagattgt caaagcgagg atgatcagag
    34861 aaccgatggc taggatggaa gtgttaagat gttgaaagga ggcaaaaaga ctattttgca
    34921 gtttatcgta ttcgtttgga tccattagga cttgaaggaa ggtgctgata tttcgaaaga
    34981 gacttctgag cgctagacag atcagcagga tgaagaccag gtcttgcttc atcagtgtct
    35041 tcaagtaacc ttgtaaggcg agaaagaaga gggactggac aagaagtaag actaggaatt
    35101 ctaagatagg ggatttgccc agttgaagaa acttgctttc aaaaaccagt agtagggttt
    35161 gtagtaggac gtagaaggat tcaattccca aaatactagg cgtcaggaag cgattttccg
    35221 tcagggtttg aaaactaatg gtcgaaatcc cagtcgcgat ggctaccaag agataaacga
    35281 tgatcttttg ggaacgcaac ttccaagcaa aggctgacaa gtgagtgatg ggccaaaagt
    35341 agagaagaca agctccgatg gcaagaataa tgagaatcca gaagagcttg gtatgtttgc
    35401 ttttagtctg catcttttcg tccccctctc cagagaagta ggataaagac gagactaccg
    35461 atgattccta gcaagagact gacagacaac tcatagggcc taatcagaac tcgggatagg
    35521 atatcgcaag ccagaactag attggcacca accagtgcga ccatgagttt ggtttgactt
    35581 agattatctc catagcgctt gcgaacaaga ttgggaacga taactccgag aaatggtaag
    35641 ccacccacgg taatcatggt gacgcttgtc gttagcgcca ccagaaagag ggccagtttt
    35701 tcaagtaggg agtaggaaat ccccaaaccc tcgctggttt ctttccccag attcatgatg
    35761 gtgaaggttt gggataattt ccaaacggtt atcaggatga tgaggcctaa gaagagccac
    35821 tcatactgat gggtctgaat catggagaag gagccctggg tccaggcagt catactctga
    35881 accagattga aacgataggc gataacttct gtgactgagc cgataatccc gctatagatg
    35941 atcccaatca gaggcaacat ccacctttcc tttacagtaa aaatggtcat aaaggctagg
    36001 aagaagaggg tgaatacgat ggatgaaaca aaagcgaaga gcatcttttg ggtcagacta
    36061 gccgatggaa agacaaaaag gctcagcacc attcccagtt tggcggcttc agtcgttcca
    36121 actgtactcg gtgcagcaaa ctgattttgg gtaatagtct gcatgagaag gcctgccata
    36181 ctcatactag aggcagtcag gagaatactg atagttcttg ggagacggga ctcttgaaag
    36241 aggagccagg tctgctggtc gaaatcaaat agctttcccc atgaaaaatc actggtccca
    36301 atgctaatag agagaaagac taggagtaga agtaagccaa ttaaataatg agaaagtttc
    36361 ataccccgtc ctttcatgta gatttggtat cgaaagatat ctgcggatat aaatgtaaca
    36421 ttatttttct aatctgtcaa taaaatttct gacaatttaa taaatacaac aaggagagag
    36481 caacaagact ttctcctttg ttatcctatt ctaaaatgtt tttaccttaa tctgataaaa
    36541 taatatcttc gagggagtag ctagccgtcc aatcaagata ttgtttagct tttgaagcat
    36601 ctgctaggac actggctggg tcactagcac gtcgagcaac aatctcgtgt gggatttttt
    36661 aatttagtaa ttcttcagca gttttaaaga tttctttgat agtatagcct tttttagttc
    36721 ctaagttaaa gatttgagaa gaactgtctt cttgaaatag gtagttcatt cctttaacat
    36781 gagcctatgc aaggtccaag acataaatgt aatctcgaat acatgaaccg tcacgtgtat
    36841 cgtagtcatc tccaaatatt tttaagctat catgttgtcc caatgcggtc ttgttgatat
    36901 ttggaatgat gtgagttgga tttttcacac gcagaccgtt tgaagcatcc atttcagccc
    36961 cagcaacatt aaagtaacgg aaaataacat atttccagtc gtagcgattg gccatccagt
    37021 aaatcattcg ttcgcccatc agttttgtct ctgcataagg gttgacaggg tcgagcaggg
    37081 tatcttcagt caccggcttg tcaatacagt tatttccata gagagaagca gtcgaagaga
    37141 acatgatttt ttgaatgcca acttcagata agactttgag aacttggttc ataccagcaa
    37201 cgttggcagt gaagtattta cttggatttt caatactttc gctcacaaca atttcacctg
    37261 cacaatggag gacagcatca atctgatttt cttctaagta agcctttaag gcgctagcat
    37321 cataaacatc cagttcttta aagctagcac gactatccac agccgctcga tttcctgtgg
    37381 agagattatc gaggacatgc acctgatagc cagcatttaa aagagcttta acggtatggg
    37441 agccaatgta gctagtccca cctgtaacaa gaattgtttt ggtcatgatt ttttcctttt
    37501 ctagttttgt actatagtaa attgaaataa gatatgaaca actctattag gaaagtcgaa
    37561 ttaatttcta gaaatgtttc agcagctaca gcgtactatt ccaaactcaa ccaactatat
    37621 atttaaagaa agaagaaagg gaagtcaact attttctgta aatttcatga aaaatccaaa
    37681 caactttgat ggtgtattgt tttttttgtt tggaaataaa tattcgagtt aattttggaa
    37741 tgtttactag attttgcact acatgcaaga gaatactatc cttttctaag atagagcagg
    37801 actaagatac taacttagaa atccaccttc ccactatcct tctcctataa aaagtggtaa
    37861 aatggatgaa agaaagaagg aactgaaatg acaacattat tttcaaaaat taaagaagta
    37921 acagaacttg ctgcagtctc aggtcatgaa gcgcctgtcc gtgcttatct tcgtgaaaag
    37981 ttgacaccgc atgtggatga agtggtgaca gatggcttgg gtggtatttt tggtatcaaa
    38041 cattcagaag ctgtggatgc accgcgcgtc ttggtcgctt ctcatatgga cgaagttggt
    38101 tttatggtca gcgaaatcaa gccagatggt accttccgtg tcgtagaaat cggtggctgg
    38161 aaccccatgg tagttagcag ccaacgtttc aaactcttga ctcgtgatgg tcatgaaatt
    38221 cctgtgattt caggttctgt tcctccgcat ttgactcgtg gaaagggggg accaaccatg
    38281 ccagccattg ccgatatcgt ttttgatggt ggttttgcgg acaaggatga ggcagaaagt
    38341 tttggcatcc gtcctggtga taccatcgta ccagatagtt ctgcaatttt gacagccaat
    38401 gaaaaaaata tcatctcaaa agcttgggat aaccgctacg gtgtcctcat ggtaagcgag
    38461 ctagctgaag ctttatcagg tcaaaaactc ggcaatgaac tctatctggg ttctaacgtc
    38521 caagaagaag ttggtctgcg tggcgctcat acctctacaa ccaagtttga cccagaagtc
    38581 ttcctcgcag ttgattgctc accagcaggt gatgtctacg gtggtcaagg caagattgga
    38641 gatggaacct tgattcgttt ctatgatcca ggtcacttgc ttctcccagg gatgaaggat
    38701 tttcttttga caacggctga agaagctggt atcaagtacc aatactactg tggtaaaggc
    38761 ggaacagatg caggtgcagc tcatctgaaa aatggtggtg tcccatcaac aactatcggt
    38821 gtctgcgctc gttatatcca ttctcaccaa accctctatg caatggatga cttcctagaa
    38881 gcgcaagctt tcttacaagc cttggtgaag aaattggatc gttcaacggt tgatttgatt
    38941 aaacattatt aaaccataag ggaggtggta gggatggcag aaccaaacct agaaagcctt
    39001 ataaaagatc tttacaatca tgctcgacat gatttgagtg aagatttagt tgctgctctc
    39061 ctagagactg ctaaaaaact gcctactaca aatgagcaat tgcaggcagt tcgtctctca
    39121 ggcctggtca atcgtgaatt gctcctaaat cccaaacatc cagcacctga gttgctcaac
    39181 ttggctcgct ttatcaaaag agaagaagcc aagtacagag gaactgcgac ttctgcgctt
    39241 atgtatgagg aactctttaa aatgctttga ttccattgtg gatcaaagca ttttttgtaa
    39301 gatctatctc gtgagcgttc aaatagtagt aacaaggaat catgagaagt cagccgagcc
    39361 catagtagtg aagaaacttc tgtaatggaa gtggagcgaa gtgaggaatc gtcaaacggt
    39421 aggggatagg ctgtttgaag ggtgctacga aaaagatagg gtaaggtgaa attatagcgg
    39481 aatgaaataa gatatgaaca aattgattga ggaaattaaa tgaatttata gaaatctttt
    39541 agcagtcatg gtgtcctatt ccagtttcga aatgctataa atacgaacaa attgattggg
    39601 aaattcaaat cgctttctat caatgtttta gaagatacag tgctctagtc taacttcaat
    39661 atactataaa agaacagatg gaagcaatta tgatttactt ctatctttaa aataaatggt
    39721 ctgataggaa aaatgtgtcc cctcataaaa tataggatag tacgaatgga aggcttttgt
    39781 agactggagg acgaaggagt ttagaaactc tcgttaaaag ttagttgagc cggagtatgg
    39841 tggtgtggat aattatcaaa aattatttct aaatcgaaat agttgacagt tagaacgatg
    39901 agtgttacaa ttgttttatt catttcgata tcgaaataaa ttggaggtgt tatgaaagat
    39961 ggtcatttgc tagcccatca tattcgtttg ttgaatgggc ggatttttca aaagttactg
    40021 agtcaagatc ctgaggctct ttataggggt gaacagggca agattttagc ggttttatgg
    40081 aatagtgaaa ctggctgcgc aactgcgaca gatatcgcgc ttgcgactgg gcttgcgaat
    40141 aatacgctaa cgactatgat aaaaaagcta gaggaacaaa agcttgtaat tgttagtccg
    40201 tgtggaaaag acaagcgtaa gaagtattta gttttaacgg agttaggcaa gtcccagaaa
    40261 gaagtggggc atcgtgtcag tcagaaattg gatactatct tttacaaagg attttcagag
    40321 gaagaaattc accaatttga aggttttcaa gaaagaattt tggcgaattt gaaagagaag
    40381 ggaaatgagg tttagaatat gtcacaacaa gtgaaaaatg ctcacaacct atacatccat
    40441 gccattcaag acggacgagt tgctgaggct caagcccagt ctgtagggga tacctatatc
    40501 caacattcga caggtgttcc tgacgggaaa gaaggatttg cagccttctt tgcagatttc
    40561 tttgagcgtc atccagagcg tcagattaag attgtccgca ccattgagga tggcaatctg
    40621 gtctttgttc atgttcatca atatctgaat ggtggagaag ctcaatgggt gacgacggat
    40681 actttccgtg cggatgagaa tggtcgtatt gttgagcatt gggatgtcat tgactactat
    40741 cgaacacctg aaaatgatca actagatcaa atttttggag attttgaaat caaggatttg
    40801 gacaagaaag cagaaaataa aaaactggtt cgccgtttct tgacagaaat tttccaaaat
    40861 ggggagctag agcagtggag tgattatgtg gcagacgatt tgattcagca taatcatgag
    40921 attggacaag gaagtgctgc ttataaaaac tatgtggctg aatatagtgt cacttttgac
    40981 tttgttttcc aactcttagg acaaggaaac tatgtggtta gctatggtca gactcagatt
    41041 gatggcgttg cttatgccca gtacgatatc ttccgtttag agaacgggaa aattgtggag
    41101 cattgggata ataaggaagt catgcctaag gtagaagact tgactaatcg agggaagttt
    41161 taaattgagg acaaagaatg attgaataca aaaatgtagc actgcgctac acagaaaagg
    41221 atgtcttgag agatgtcaac ttacagattg aggatgggga atttatggtt ttagtagggc
    41281 cttctgggtc aggtaagacg accatgctca agatgattaa ccgtcttttg gaaccaactg
    41341 atggaaatat ttatatggat gggaagcgca tcaaagacta tgatgagcgt gaacttcgtc
    41401 tttctactgg ttatgtttta caggctattg ctctttttcc aaatctaaca gttgcggaaa
    41461 atattgctct cattcctgaa atgaaggggt ggagcaagga agaaattacg aagaaaacag
    41521 aagagctttt ggctaaggtt ggtttaccag tagccgagta tgggcatcgc ttacctagtg
    41581 aattatctgg tggagaacag caacgggtcg gtattgtccg agctatgatt ggtcagccca
    41641 agattttcct catggatgaa cccttttcgg ccttggatgc tatttcgaga aaacagttgc
    41701 aggttctgac aaaagaattg cataaagagt ttgggatgac aacgattttt gtaacccatg
    41761 atacggatga agccttgaag ttggcggacc gtattgctgt cttgcaggat ggagaaattc
    41821 gccaggtagc gaatcccgag acaattttaa aagtgcctgc aacagacttt gtagcagact
    41881 tgtttggagg tagtgttcat gactaattta attgcaactt ttcaggatcg ttttagtgat
    41941 tggttgacag ctctatctca acatttgcag ttgtcacttt tgaccttgtt actagctatt
    42001 ttgcttgcga ttcccttggc tgtttttctt cgctatcatg agaagctggc cgactgggtc
    42061 ttgcagattg caggtatttt ccagaccatc ccgtctctgg ccttgttggg gctctttatc
    42121 cctttgatgg gaattgggac cttgccggct ttgacagctc tagtgattta tgcgattttt
    42181 ccgattttac aaaatactat tactgggctg aagggaattg atccgagtct tcaagaggct
    42241 gggattgcct ttgggatgac cagatgggag cgtctcaaga agtttgaaat tccacttgcc
    42301 atgcctgtta tcatgtctgg aattcggacg gcagcggtct tgattatcgg tacggctacc
    42361 ttggcgacct tgattggggc agggggactg ggttccttta tcctgttggg aattgaccgt
    42421 aataatgcca gtttgatttt gattggggcc ctttcttctg cagtgctagc tattgccttt
    42481 aacttcctac taaaagtaat ggaaaaagcg aaattgcgga cgattttctc tggttttgcc
    42541 ttggtggctt tattactggg tctgtcttat agtccagccc ttttggctca aaaagagaag
    42601 gaaaacttga ttattgctgg gaaaataggc ccagaaccag aaattttggc taatatgtat
    42661 aaattgctga ttgaagaaaa taccagcatg actgcgactg ttaaaccgaa ttttgggacg
    42721 acaagtttcc tttatgaagc tctgaaaaaa ggtgatattg acatttatcc tgaatttacc
    42781 ggtacggtga ctgaaagttt gcttcaacca tcacccaagg tgagtcatga gccagagcag
    42841 gtttatcaag tggcgcgtga tggcattgcc aagcaggatc atctagccta tctcaaacct
    42901 atgtcttatc aaaataccta tgctgtagct gttccgaaaa agattgctca agaatatggc
    42961 ttgaagacca tttcggattt gaaaaaagtg gaagggcagc tgaaggcagg ctttacgctt
    43021 gagtttaacg accgtgaaga tggaaataag ggcttgcaat caatgtatgg tctcaatctc
    43081 aatgtggcga ctatgcagcc agctcttcgt tatcaggcaa ttcagtcagg ggatattcaa
    43141 atcacggatg cctattcgac tgatgcggaa ttggagcgtt atgatttaca ggtcttggaa
    43201 gatgacaagc aactcttccc accttatcaa ggggctccac tcatgaaaga agctcttctc
    43261 aagaaacacc cagagttgga aagagttctt aatacattgg ctggtaagat tacagaaagc
    43321 cagatgagcc agctcaacta ccaagtcggt gttgaaggca agtcagcaaa gcaagtagcc
    43381 aaggagtttc tccaagaaca aggtttgttg aagaaatgat gggacagaga ctt
//
LOCUS       DAVBOG010000012        42874 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.012, whole genome shotgun sequence.
ACCESSION   DAVBOG010000012 DAVBOG010000000
VERSION     DAVBOG010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 42874)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42874)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42874
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.012"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(15..1973)
                     /gene="ftsH"
                     /locus_tag="VQ865_000705"
     CDS             complement(15..1973)
                     /gene="ftsH"
                     /locus_tag="VQ865_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HET3135094.1"
                     /translation="MKKQNNGLIKNPFLWLLFIFFLVTGFQYFYSGNNSGGSQQINYT
                     ELVQEITDGNVKELTYQPNGSVIEVSGVYKNPKTSKEETGIQFFTPSVTKVEKFTSTI
                     LPADTTVSELQKLATDHKAEVTVKHESSSGIWINLLVSIVPFGILFFFLFSMMGNMGG
                     GNGRNPMSFGRSKAKAANKEDIKVRFSDVAGAEEEKQELVEVVEFLKDPKRFTKLGAR
                     IPAGVLLEGPPGTGKTLLAKAVAGEAGVPFFSISGSDFVEMFVGVGASRVRSLFEDAK
                     KAAPAIIFIDEIDAVGRQRGVGLGGGNDEREQTLNQLLIEMDGFEGNEGIIVIAATNR
                     SDVLDPALLRPGRFDRKVLVGRPDVKGREAILKVHAKNKPLAEDVDLKLVAQQTPGFV
                     GADLENVLNEAALVAARRNKSIIDASDIDEAEDRVIAGPSKKDKTVSQKERELVAYHE
                     AGHTIVGLVLSNARVVHKVTIVPRGRAGGYMIALPKEDQMLLSKEDMKEQLAGLMGGR
                     VAEEIIFNVQTTGASNDFEQATQMARAMVTEYGMSEKLGPVQYEGNHAMFGAQSPQKS
                     ISEQTAYEIDEEVRSLLNEARNKAAEIIQSNREIHKLIAEALLKYETLDSTQIKALYE
                     TGKMPEAVEEESHALSYDEVKSKMNDEK"
     gene            complement(1989..2531)
                     /gene="hpt"
                     /locus_tag="VQ865_000706"
     CDS             complement(1989..2531)
                     /gene="hpt"
                     /locus_tag="VQ865_000706"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HET3135095.1"
                     /translation="MLENDIKKVLVSHDEITEAAKKLGAQLTKDYAGKNPILVGILKG
                     SIPFMAELVKHIDTHIEMDFMMVSSYHGGTASSGVINIKQDVTQDIKGRHVLFVEDII
                     DTGQTLKNLRDMFKAREAASVKIATLLDKPEGRVVEIEADYTCFTIPNEFVVGYGLDY
                     KENYRNLPYIGVLKEEVYSN"
     gene            complement(2535..3812)
                     /gene="tilS"
                     /locus_tag="VQ865_000707"
     CDS             complement(2535..3812)
                     /gene="tilS"
                     /locus_tag="VQ865_000707"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HET3135096.1"
                     /translation="MREPDFLNHFLKKGYFKKHAKAVLALSGGLDSMFLFKVLSTYQK
                     ELEIELILAHVNHKQRIESDWEEKELRKLAAEAELPIYISNFSGEFSEARARNFRYDF
                     FQEVMKKTGATALVTAHHADDQVETILMRLIRGTRLRYLSGIKEKQVVGEIEIIRPFL
                     HFQKKDFPSIFHFEDTSNQENHYFRNRIRNSYLPELEKENPRFRDAILGIGNEILDYD
                     LAIAELSNNINVEDLQQLFSYSESTQRVLLQTYLNRFPDLNLTKAQFAEVQQILKSKS
                     QYRHPIKNGYELIKEYQQFQICKISPQADEEEDELVLHYQNQVAYQGYLFSFGLPLEG
                     ESIQQIPVSRETSIHIRHRKTGDVLIQNGHRKKLRRLFIDLKIPMEKRNSALIIEQFG
                     EIVSILGIATNNLSKKTKNDIMNTVLYIEKIDR"
     gene            complement(3809..5077)
                     /locus_tag="VQ865_000708"
     CDS             complement(3809..5077)
                     /locus_tag="VQ865_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A beta-lactamase-related serine hydrolase"
                     /protein_id="HET3135097.1"
                     /translation="MRKFLIILLLPSFLTISKVVSTEKEVVYTSKEIYYLSQSDFGIY
                     FREKLSSPMVYGEVPVYANEDLVVESGKLTPKTSFQITEWRLNKQGIPVFKLSNHQFI
                     AADKRFLYDQSEVTPTIKKAWLESDFKLYNSPYDLKEVKSSLSAYSQVSIDKTMFVEG
                     REFLHIDQAGWVAKESTSEEDNRMSKVQEMLSEKYQKDSFSIYVKQLTTGKEAGINQD
                     EKMYAASVLKLSYLYYTQEKINEGLYQLDTTVKYVSAVNDFPGSYKPEGSGSLPKKED
                     NKEYSLKDLITKVSKESDNVAHNLLGYYISNQSDATFKSKMSAIMGDDWDPKEKLISS
                     KMAGKFMEAIYNQNGFVLESLTKTDFDSQRIAKGVSVKVAHKIGDADEFKHDTGVVYA
                     DSPFILSIFTKNSDYDTISKIAKDVYEVLK"
     gene            complement(5197..5565)
                     /locus_tag="VQ865_000709"
     CDS             complement(5197..5565)
                     /locus_tag="VQ865_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HET3135098.1"
                     /translation="MSKNIVQLNNSFIQNEYQRRRYLMKERQKRNRFMGGVLILIMLL
                     FILPTFNLAQSYQQLLQRRQQLADLQTQYQTLSDEKDKETAFATKLKDEDYAAKYTRA
                     KYYYSKSREKVYTIPDLLQR"
     gene            complement(5558..5824)
                     /locus_tag="VQ865_000710"
     CDS             complement(5558..5824)
                     /locus_tag="VQ865_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HET3135099.1"
                     /translation="MRLDKYLKVSRIIKRRTVAKEVADKGRIKVNGILAKSSTDLKVN
                     DQVEIRFGNKLLLVKVLEMKDSTKKEDAAGMYEIISETRVEENV"
     gene            complement(5882..9391)
                     /gene="mfd"
                     /locus_tag="VQ865_000711"
     CDS             complement(5882..9391)
                     /gene="mfd"
                     /locus_tag="VQ865_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000258090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HET3135100.1"
                     /translation="MVTLLDLFSENDQIKKWHQNLTDKKRQLILGLSTSTKALAIASS
                     LEKEDRIVLLTSTYGEAEGLVSDLISILGEELVYPFLVDDAPMVEFLMSSQEKIISRV
                     EALRFLTDSSKKGILVCNIAASRLILPSPNAFKDSIVKISVGEEYAQHAFIHQLKENG
                     YRKVTQVQTQGEFSLRGDILDIFEISQLEPCRIEFFGDEIDGIRSFEVETQLSKENKT
                     ELTIFPASDMLLREKDYQRGQSALEKQISKTLSPILKSYLEEILSSFHQKQSHADSRK
                     FLSLCYDKTWTVFDYIEKDTPIFFDDYQKLMNQYEVFERELAQYFTEELQNSKAFSDM
                     QYFSDIEQIYKKQSPVTFFSNLQKGLGNLKFDKIYQFNQYPMQEFFNQFSFLKEEIER
                     YKKMDYTIILQSSNSMGSKTLEDMLEEYQIKLDSRDKTSICKESVNLIEGNLRHGFHF
                     VDEKILLITEHEIFQKKLKRRFRRQHVSNAERLKDYNELEKGDYVVHHIHGIGQYLGI
                     ETIEIKGIHRDYVSVQYQNGDQISIPVEQIHLLSKYISSDGKAPKLNKLNDGHFKKAK
                     QKVKNQVEDIADDLIKLYSERSQLKGFAFSADDDDQDAFDDAFPYVETDDQLRSIEEI
                     KRDMQASQPMDRLLVGDVGFGKTEVAMRAAFKAVNDHKQVVILVPTTVLAQQHYTNFK
                     ERFQNFAVNVDVLSRFRSKKEQTATLEKLKNGQVDILIGTHRVLSKDVVFADLGLMII
                     DEEQRFGVKHKETLKELKKQVDVLTLTATPIPRTLHMSMLGIRDLSVIETPPTNRYPV
                     QTYVLEKNDSVIRDAVLREMERGGQVYYLYNKVDTIVQKVSELQELIPEASIGYVHGR
                     MSEVQLENTLLDFIEGQYDILVTTTIIETGVDIPNANTLFIENADHMGLSTLYQLRGR
                     VGRSNRIAYAYLMYRPEKSISEVSEKRLEAIKGFTELGSGFKIAMRDLSIRGAGNLLG
                     KSQSGFIDSVGFELYSQLLEEAIAKRNGNANANTRTKGNAELILQIDAYLPDTYISDQ
                     RHKIEIYKKIRQIDNRVNYEELQEELIDRFGEYPDVVAYLLEIGLVKSYLDKVFVQRV
                     ERKDNKITIQFEKVTQRLFLAQDYFKALSVTNLKAGIAENKGLMELVFDVQNKKDYEI
                     LEGLLIFGESLLEIKESKEENSI"
     gene            complement(9392..9961)
                     /locus_tag="VQ865_000712"
     CDS             complement(9392..9961)
                     /locus_tag="VQ865_000712"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HET3135101.1"
                     /translation="MTKLLVGLGNPGDKYFETKHNVGFMLIDQLAKKQNVTFTHDKIF
                     QADLASFFLNGEKIYLVKPTTFMNESGKAVHALLTYYGLDIDDLLIIYDDLDMEVGKI
                     RLRAKGSAGGHNGIKSIIQHIGTQVFNRVKIGIGRPKNGMSVVHHVLSKFDRDDYIGI
                     LQSVDKVDDSVNYYLQEKNFEKTMQRYNG"
     gene            complement(10032..11147)
                     /gene="ychF"
                     /locus_tag="VQ865_000713"
     CDS             complement(10032..11147)
                     /gene="ychF"
                     /locus_tag="VQ865_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002269933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HET3135102.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDERLQKLTEMITPKKTVPTTFEFTDIAGIVKGASKGEGLGNKFLANIREVDAIVH
                     VVRAFDDENVMREQGREDAFVDPLADIDTINLELILADLESVNKRYARVEKMARTQKD
                     KESVAEFNVLQKIKPVLEDGKSARTIEFTDEEQKVVKGLFLLTTKPVLYVANVDEDVV
                     SEPDSIDYVKQIREFAATENAEVVVISARAEEEISELDDEDKKEFLEAIGLTESGVDK
                     LTRAAYHLLGLGTYFTAGEKEVRAWTFKRGMKAPQAAGIIHSDFEKGFIRAVTMSYED
                     LVKYGSEKAVKEAGRLREEGKEYIVQDGDIMEFRFNV"
     gene            complement(11231..11425)
                     /locus_tag="VQ865_000714"
     CDS             complement(11231..11425)
                     /locus_tag="VQ865_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 family protein"
                     /protein_id="HET3135103.1"
                     /translation="MYQVGNFVEMKKPHACTIKSTGKKANRWEITRVGADIKIKCSNC
                     EHVVMMGRYDFERKMNKIID"
     gene            complement(11490..12626)
                     /gene="dnaN"
                     /locus_tag="VQ865_000715"
     CDS             complement(11490..12626)
                     /gene="dnaN"
                     /locus_tag="VQ865_000715"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HET3135104.1"
                     /translation="MIHFSINKNLFLQALNTTKRAISSKNAIPILSTVKIDVTNEGIT
                     LIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQN
                     QIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRP
                     ILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDD
                     IETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSME
                     RARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYL
                     IDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN"
     gene            complement(12785..14146)
                     /gene="dnaA"
                     /locus_tag="VQ865_000716"
     CDS             complement(12785..14146)
                     /gene="dnaA"
                     /locus_tag="VQ865_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HET3135105.1"
                     /translation="MKEKQFWNRILEFAQERLTRSMYDFYAIQAEVIKVEENVATIFL
                     PRSEMEMVWEKQLKDIIVVAGFEIYDAEITPHYIFTKPQDTTSSQVEEATNLTLYDYS
                     PKLVSIPYSDTGLKEKYTFDNFIQGDGNVWAVSAALAVSEDLALTYNPLFIYGGPGLG
                     KTHLLNAIGNEILKNIPNARVKYIPAESFINDFLDHLRLGEMEKFKKTYRSLDLLLID
                     DIQSLSGKKVATQEEFFNTFNALHDKQKQIVLTSDRSPKHLEGLEERLVTRFSWGLTQ
                     TITPPDFETRIAILQSKTEHLGYNFQSDTLEYLAGQFDSNVRDLEGAINDITLIARVK
                     KIKDITIDIAAEAIRARKQDVSQMLVIPIDKIQTEVGNFYGVSIKEMKGSRRLQNIVL
                     ARQVAMYLSRELTDNSLPKIGKEFGGKDHTTVIHAHAKIKSLIDQDDNLRLEIESIKK
                     KIK"
     gene            complement(14359..15117)
                     /locus_tag="VQ865_000717"
     CDS             complement(14359..15117)
                     /locus_tag="VQ865_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HET3135106.1"
                     /translation="MEKFEMISITDIQKNPYQPRKEFDREKLDELAQSIKENGVIQPI
                     IVRQSPVIGYEILAGERRYRASLLAGLRSIPAVVKQISDQEMMVQSIIENLQRENLNP
                     IEEARAYESLVEKGFTHAEIADKMGKSRPYISNSIRLLSLPEQILSEVENGKLSQAHA
                     RSLVGLNKEQQDYFFQRIIEEDISVRKLEALLTEKKQKKQQKTNHFIQNEEKQLRKLL
                     GLDVEIKLSKKDSGKIIISFSNQEEYSRIINSLK"
     gene            complement(15175..16356)
                     /locus_tag="VQ865_000718"
     CDS             complement(15175..16356)
                     /locus_tag="VQ865_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HET3135107.1"
                     /translation="MKHLKTFYKKWFQLLVVIVISFFSGALGSFSITQLTQKSSVNNS
                     NNNSTITQTAYKNENSTTQAVNKVKDAVVSVITYSANRQNSVFGNDDTDTDSQRISSE
                     GSGVIYKKNDKEAYIVTNNHVINGASKVDIRLSDGTKVPGKIVGADTFSDIAVVKISS
                     EKVTTVAEFGDSSKLTVGETAIAIGSPLGSEYANTVTQGIVSSLNRNVSLKSEDGQAI
                     STKAIQTDTAINPGNSGGPLINIQGQVIGITSSKIATNGGTSVEGLGFAIPANDAINI
                     IEQLEKNGKVTRPALGIQMVNLSNVSTSDIRRLNIPSNVTSGVIVRSVQSNMPANGHL
                     EKYDVITKVDDKEIASSTDLQSALYNHSIGDTIKITYYRNGKEETTSIKLNKSSGDLE
                     S"
     gene            16539..17018
                     /gene="rlmH"
                     /locus_tag="VQ865_000719"
     CDS             16539..17018
                     /gene="rlmH"
                     /locus_tag="VQ865_000719"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HET3135108.1"
                     /translation="MKIKVVTVGKLKEKYLKDGIAEYSKRISRFAKFEMIELSDEKTP
                     DKASESENQKILEIEGQRILSKIADRDFVIVLAIEGKTFFSEEFSKQLEETSIKGFST
                     LTFIIGGSLGLSSSVKNRANLSVSFGRITLPHQLMRLVLVEQIYRAFTIQQGFPYHK"
     gene            17062..17135
                     /locus_tag="VQ865_000720"
     tRNA            17062..17135
                     /locus_tag="VQ865_000720"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:17096..17098,aa:Arg,seq:tct)
     gene            17300..17425
                     /gene="comC"
                     /locus_tag="VQ865_000721"
     CDS             17300..17425
                     /gene="comC"
                     /locus_tag="VQ865_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence-stimulating peptide ComC"
                     /protein_id="HET3135109.1"
                     /translation="MKNTVKLEQFVALKEKDLQKIKGGEMRLSKFFRDFILQRKK"
     gene            17446..18771
                     /locus_tag="VQ865_000722"
     CDS             17446..18771
                     /locus_tag="VQ865_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000362880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3135110.1"
                     /translation="MDLFGFGTVIVHFLIISHSYHFICKGQINRKELFVFGAYTLLTE
                     IVFDFPLYILYLDGLGIERFLFPLGLYSYFRWMKQYERDRGLFLSLLLSLLYESTHNF
                     LSVTFSSITGDNFVLQYHFPFFFVVTVLTYFVTLKIIYYFHLELAYFDEDYLYPFLKK
                     VFFALLLLHIVSFVSDMVSTIKHLNSFGSILSSIVFISLLLTFFAMNSHKVQMEKEIA
                     LKQKKFEQKHLQNYTDEIVGLYNEIRGFRHDYAGMLVSMQMAIDSGNLQEIDRIYNEV
                     LVKANHKLRSDKYTYFDLNNIEDSALRSLVAQSIVYARNNGVEFTLEVKDTITKLPIE
                     LLDLVRIMSVLLNNAVEGSADSYKKQMEVAVIKMETETVIVIQNSCKMTMTPSGDLFA
                     LGFSTKGRNRGVGLNNVKELLDKYNNIILETEMEGSTFRQIIRFKREFE"
     gene            18768..19520
                     /locus_tag="VQ865_000723"
     CDS             18768..19520
                     /locus_tag="VQ865_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000866085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135111.1"
                     /translation="MKVLILEDVIEHQVRLERILDEISKESNIPISYKTTGKVREFEE
                     YIENDEVNQLYFLDIDIHGIEKKGFEVAQLIRHYNPYAIIVFITSRSEFATLTYKYQV
                     SALDFVDKDINDEMFKKRIEQNIFYTKSMLLENEDVVDYFDYNYKGNDLKIPYHDILY
                     IETTGVSHKLRIIGKNFAKEFYGTMTDIQEKDKHTQRFYSPHKSFLVNIGNIREIDRK
                     NLEIVFYEDHRCPISRLKIRKLKDILEKKSQK"
     gene            19572..19643
                     /locus_tag="VQ865_000724"
     tRNA            19572..19643
                     /locus_tag="VQ865_000724"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19605..19607,aa:Glu,seq:ttc)
     gene            19649..19722
                     /locus_tag="VQ865_000725"
     tRNA            19649..19722
                     /locus_tag="VQ865_000725"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:19683..19685,aa:Asn,seq:gtt)
     gene            complement(19763..20305)
                     /locus_tag="VQ865_000726"
     CDS             complement(19763..20305)
                     /locus_tag="VQ865_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HET3135112.1"
                     /translation="MQESNKRLKTKRTIENAMVQLLMEQPFDKISTVKLVEKAGISRS
                     SFYTHYKDKYDMIEHYQSKLFHTFEYIFQKHAHHKRDAILEVFEYLESEPLLAALLSE
                     NGTKEIQNFLRNKLHIMLSTDLQKRFMQLNLNTTELEYSSIYLTHALFGVCQTWIAHG
                     KKESSQEITDFLMKMLGDTN"
     gene            20484..21251
                     /locus_tag="VQ865_000727"
     CDS             20484..21251
                     /locus_tag="VQ865_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HET3135113.1"
                     /translation="MIGISLIPDLYNIIFLSSMWDPYGQLSDLPVAVVNNDKEASYNG
                     NTMAIGKDMVSNLKENKTLDFHFVDEEEGKKGLEDGDYYMVVTLPSDLSEKTTTLSNI
                     QSTAAYQSLTSEQQTEISDSVSQNSTDSIQSAQSIVALVQDLQGSLENLQNQSSNLST
                     LKNQSNQVSPITSTSLIGLSSGLTEIQGDVTSKLVPASQSIASGVNAYTTGVDKVSQG
                     ASQLSEKNATLTGSLDKLVSGSNTLTQKSSRLTAGVG"
     gene            21255..21674
                     /locus_tag="VQ865_000728"
                     /pseudo
     CDS             21255..21674
                     /locus_tag="VQ865_000728"
                     /inference="COORDINATES: protein motif:HMM:TIGR03057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            21702..22016
                     /locus_tag="VQ865_000729"
     CDS             21702..22016
                     /locus_tag="VQ865_000729"
                     /inference="COORDINATES: protein motif:HMM:TIGR03062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip family protein"
                     /protein_id="HET3135114.1"
                     /translation="MAGILVYGGVQLIGLTANHEMRIFILIILTSLVFMSMVTTLATW
                     NSRIGAFFSLILLLLQLASSAGTYPLALTNDFFRSINPWLPMSYSVSGLRQTISINKS
                     FS"
     gene            complement(22117..24669)
                     /locus_tag="VQ865_000730"
     CDS             complement(22117..24669)
                     /locus_tag="VQ865_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HET3135115.1"
                     /translation="MKSFLKTYRTYFISLIIPVVIMSGVYLSQGIYWNSDNSPLLGDG
                     FHQYVIFDVALRNILHGNSSLFYTFTSGLGLNFYALSSYYLGSFLAPLVYFFDLTNMP
                     DAVYLTTLLKFGLIGLSTFFSLNKLFQSIPQTLKLALSTSYALMSFTVSQLEIKTWLD
                     VFILIPLIITGLHLLITEKKLLLYFTSLSILFIQNYYFGYMTVLFLIFWYLCQISWDF
                     KTRKSSVLDFIVISFLAGMASLIMTLPTLFDLQTHGEKLTEVTKFQTESSWYLDLFAK
                     QFIGSFDTTKYGAIPMIFVGLFPFILTILFFTLKSIKFHVKLIYVIFFAFLIASFYIE
                     ALDLFWQGMHTPNMFLHRYAWIFSTLLIYTAAEVLKRLKELKVWNFLVSLFLVVAGFL
                     ATIYLKSHYSFLTDLNILLTLEFLVVYSLLLLAVIKKFISVNLFAILISLFILVEMSL
                     NASSQMDGIAKEWGFASRSAYSRDILAMESFSTYIGNQFTRTEKLQTQTGNDSMKFNY
                     NGISQFSSVRNRSSSSTLDKLGFKSSGTNLNLRYANNSILADSLFGIQYNISDSPIDK
                     YGFKDIYQKDNLTLYENQYSLPIAVASQSVYNDVKFNEHTLDNQASFLNQLANVNFDY
                     FSPIPYEKTEKIENTNDLISVTSSSNEDAAIQYQIEVPENSQVYLSFINLHFSNDKQK
                     KVDILVNGEKKTFTTDNVFSFFNLGYTKEKKTFNINVSFPGNSQVSFESPTFYRLDTK
                     TFTEAIQKIKEQPVTVSTSKNKVFATYDVQQDTSIFFTIPYDKGWSAYQDGKKIEIKQ
                     AQTGFMKVDIPKGKGTITLSFIPNGFITGAICSFTSLLLFGIYNHRRKSSKA"
     gene            complement(24731..26353)
                     /locus_tag="VQ865_000731"
     CDS             complement(24731..26353)
                     /locus_tag="VQ865_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3135116.1"
                     /translation="MLTVSDVSLRFSDRKLFDDVNIKFTEGNTYGLIGANGAGKSTFL
                     KILAGDIEPTTGHISLGPDERLSVLRQNHFDYEDERAIDVVIMGNEKLYSIMKEKDAI
                     YMKEDFSDEDGVRAAELEGEFAELGGWEAESEASQLLQNLNIPEELHYQNMSELANGE
                     KVKVLLAKALFGKPDVLLLDEPTNGLDIQSITWLEDFLIDFDNTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWKESSELAAKLLADRNAKAEEKIKQLQEFVARFSANA
                     SKSRQATSRKKMLDKIELEEIVPSSRKYPFINFKAEREIGNDLLTVENLTVKIDGETI
                     LDNISFILRPDDKTALIGQNDIQTTALIRAIMGDIDYEGTVKWGVTTSQSYLPKDNSA
                     DFAGGESILDWLRQFASKEEDDNTFLRGFLGRMLFSGDEVNKPVNVLSGGEKVRVMLS
                     KLMLLKSNVLVLDDPTNHLDLESISSLNDGLKNFKESIIFASHDHEFIQTLANHIIVL
                     SKNGVIDRIDETYDEFLENAEVQAKVKELWKD"
     gene            26559..27584
                     /gene="trpS"
                     /locus_tag="VQ865_000732"
     CDS             26559..27584
                     /gene="trpS"
                     /locus_tag="VQ865_000732"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000165445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HET3135117.1"
                     /translation="MTKPIILTGDRPTGKLHIGHYVGSLKNRVLLQEEDKYDMFVFLA
                     DQQALTDHAKDPQTIVESIGNVALDYLAVGLDPNKSTIFIQSQIPELAELSMYYMNLV
                     SLARLERNPTVKTEISQKGFGESIPTGFLVYPIAQAADITAFKANYVPVGTDQKPMIE
                     QTREIVRSFNNAYNCDVLVEPEGIYPENERAGRLPGLDGNAKMSKSLNNGIYLADDAD
                     TLRKKVMSMYTDPDHIRVEDPGKIEGNMVFHYLDVFGRPEDAQEIADMKERYQRGGLG
                     DVKTKRYLLEILERELGPIRERRIEFAKDMGEVYNMIQKGSERAREVAGQTLSEVKGA
                     MGLHYFN"
     gene            27736..29214
                     /gene="guaB"
                     /locus_tag="VQ865_000733"
     CDS             27736..29214
                     /gene="guaB"
                     /locus_tag="VQ865_000733"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HET3135118.1"
                     /translation="MSNWDTKFLKKGFTFDDVLLIPAESHVLPNDADLTTKLADNLTL
                     NIPIITAAMDTVTESQMAIAIARAGGLGVIHKNMSIAQQADEVRKVKRSENGVIIDPF
                     FLTPEHTIAEADELMGRYRISGVPVVETLENRKLVGILTNRDLRFISDYNQPISNHMT
                     SENLVTAPVGTDLATAESILQEHRIEKLPLVDEEGSLSGLITIKDIEKVIEFPNAAKD
                     EFGRLLVAGAVGVTSDTFERAEALFEAGADAIVIDTAHGHSAGVLRKIAEIRAHFPDR
                     TLIAGNIATAEGARALYEAGVDVVKVGIGPGSICTTRVIAGVGVPQVTAIYDAAAVAR
                     EYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIFQGRKFKTYRG
                     MGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAAADIVFQMIGGIRSGMGY
                     CGAANLKELHDNAQFIEMSGAGLKESHPHDVQITNEAPNYSM"
     gene            complement(29265..30362)
                     /gene="recF"
                     /locus_tag="VQ865_000734"
     CDS             complement(29265..30362)
                     /gene="recF"
                     /locus_tag="VQ865_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000266665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HET3135119.1"
                     /translation="MWLQHLSLKTFRNYKETKIDFNPKLNVFLGRNAQGKTNMLEAIY
                     FLALTRSHRTRTDKNLIHFDEEQLHLSGLVQKKTGSIPLEIELTQKGRVTKVNHLKQA
                     RLSDYVGHMNVVLFAPEDLQLIKGAPSIRRKFIDMELGQIKPIYLSDLTNYNHILKQR
                     NTYLKSAQKIDETFLSVLDDQLVDYGCRVMNHRLDFIKKLESFGRKKHFELSNQIEEL
                     SISYQSSVNITDKQNLSESFKIALEKSRSRDLFKKNTGVGPHRDDISFYINGMDASFG
                     SQGQHRSLVLSIKLAEIELMESITTESPILLLDDVMSELDNTRQLKLLETISQSIQTF
                     ITTTSLDHLQNLPENLSIFTIQDGKASVNGN"
     gene            complement(30365..30733)
                     /gene="yaaA"
                     /locus_tag="VQ865_000735"
     CDS             complement(30365..30733)
                     /gene="yaaA"
                     /locus_tag="VQ865_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HET3135120.1"
                     /translation="MEYKLFEEFITLQALLKELGITHSGGAIKSFLSEHSVYFNRELE
                     SRRGKKLRIGDKVDIPDMNIDILLTQPTSEEQDEYQADKVEKERIAKLVKKMNKGVKK
                     DKSKPASSPKSQQAPRFPGR"
     gene            30892..32142
                     /locus_tag="VQ865_000736"
     CDS             30892..32142
                     /locus_tag="VQ865_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3135121.1"
                     /translation="MELVHGISTHFIQSKKFKTNKITVRFTAPLSLDTIAGHMLSASM
                     LETANQMYPTSQDLRRHLASLYGTDMSTNCFRRGQSHIIELTFTYVRDEFLSRKNVLT
                     SQILELVKETLFSPAVVDNGFDPALFEIEKKQLLASLAADMDDSFYFAHKELDKLFFH
                     DERLQLEYSDLRNRILAETPQSSYSCFQEFLANDRIDFFFLGDFNEVEIQNVLESFGF
                     KGRKGDVKVQYCQPYSNILQEGMVRKNVGQSILELGYHYRSKYGDEQHLPMIVMNGLL
                     GGFAHSKLFTNVRENAGLAYTISSELDLFSGFLRMYAGINRENRNQARKMMNNQLLDL
                     KKGYFTEFELNQTKEMIRWSLLLSQDNQSSLIERAYQNALFGKSSADFKSWIAELEQI
                     DKDAICRVANNVKLQAIYFMEGIE"
     gene            32139..33422
                     /locus_tag="VQ865_000737"
     CDS             32139..33422
                     /locus_tag="VQ865_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HET3135122.1"
                     /translation="MTKVVFEEKYYPAVKEKVYRTRLANGLTVALLPKKEFKEVYGSV
                     TVQFGSVDTFVTEVDGYVKQYPGGIAHFLEHKLFEREDSSDLMSAFTSLGADSNAFTS
                     FTKTNYLFSATDYFLENLDLLDELVTSAHFTEASILTEQDIIQQEREMYQDDPDSCLF
                     FSTLANLYPGTPLATDIVGSEESISQINLTNLQENFTKFYKPVNMSLFLVGNFDVERV
                     QDYFESKELKDSDFQEVAREKLFLQPVKPTDSMRMEVSSPKLAIGVRGKREVSEADCY
                     RHHILLKLLFAMMFGWTSDRFQKCYESGKIDASLSLEVEITSRFHFVMLTIDTKEPVA
                     LSHQFRKAIRNFTKDLDITEEHLDIIKREMFGEFFSSMNSLEFIATQYDAFENGETIF
                     DLPKILQEITLEDVLDAGHHLIDDGDIVDFTIFPS"
     gene            33464..34285
                     /locus_tag="VQ865_000738"
     CDS             33464..34285
                     /locus_tag="VQ865_000738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3135123.1"
                     /translation="MRKKTIGEVLRLARINQGLSLDELQKKTEIQLDMLEAMEADDFD
                     QLPSPFYTRSFLKKYAWAVELDDQIVLDAYDSGSMITYEEVDVDEDELTGRRRSSKKK
                     KKKTSFLPLFYFILFALSILIFVTYYVWNYIQTQPEEPSLSNYSVVQSTSSTSSVPHS
                     SSSSSSSIESAISVSGEGNHVEIAYKTSKETVKLQLAVSDVTSWVSVSESELEGGVTL
                     SPKKKSAEATVATKSPVTITLGVVKGVDLTVDNQTVDLSKLTAQTGQITVTFTKN"
     gene            34296..34841
                     /gene="pgsA"
                     /locus_tag="VQ865_000739"
     CDS             34296..34841
                     /gene="pgsA"
                     /locus_tag="VQ865_000739"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HET3135124.1"
                     /translation="MKKEQIPNLLTIGRILFIPIFIFILTIGNSIESHIVAAIIFAVA
                     SITDYLDGYLARKWNVVSNFGKFADPMADKLLVMSAFIMLIELGMAPAWIVAVIICRE
                     LAVTGLRLLLVETGGTILAAAMPGKIKTFSQMFAIIFLLLHWTLLGQVLLYVALFFTI
                     YSGYDYFKGSAYVFKGTFGSK"
     gene            34838..35665
                     /locus_tag="VQ865_000740"
     CDS             34838..35665
                     /locus_tag="VQ865_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3135125.1"
                     /translation="MKSIIDVKNLSFRYKENQNYYDVKDITFHVKRGEWLSIVGHNGS
                     GKSTTVRLIDGLLEAESGEIVIDGQRLTEENVWNIRRQIGMVFQNPDNQFVGATVEDD
                     VAFGLENQGLSRQEMKKRVEEALALVGMLDFKKREPARLSGGQKQRVAIAGVVALRPA
                     ILILDEATSMLDPEGRRELIGTVKGIRKDYDMTVISITHDLEEVAMSDRVLVMKKGEI
                     ESTSSPRELFSRNDLDQIGLDDPFANQLKKSLSQNGYDLPENYLTESELEDKLWELL"
     gene            35650..36489
                     /locus_tag="VQ865_000741"
     CDS             35650..36489
                     /locus_tag="VQ865_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter ATPase"
                     /protein_id="HET3135126.1"
                     /translation="MGIALENVNFIYQEGTPLASAALSDVSLTIEDGSYTALIGHTGS
                     GKSTILQLLNGLLVPSQGSVRVFDTLITSTSKNKDIRQIRKQVGLVFQFAENQIFEET
                     VLKDVAFGPQNFGVSEEDAVKTAREKLALVGIDESLFDRSPFELSGGQMRRVAIAGIL
                     AMEPSILVLDEPTAGLDPLGRKELMTLFKKLHQSGMTIVLVTHLMDDVAEYANQVYVM
                     EKGRLVKGGKPSDVFQDVVFMEEVQLGVPKITAFCKRLADRGVSFKRLPIKIEEFKES
                     LNG"
     gene            36482..37276
                     /locus_tag="VQ865_000742"
     CDS             36482..37276
                     /locus_tag="VQ865_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3135127.1"
                     /translation="MDSMILGRYIPGDSIVHRLDPRSKLLAMMLLILIVFWANNPLTN
                     LILFIATGIFIALSGVSLSFFIQGLKSMFFLIAFTTIFQLFFISNGNVLFEFSFVRIT
                     DYALQQAGIIFCRFVLIIFFSTLLTLTTMPLSLASAVEALLAPLKRVKVPVHEIGLML
                     SMSLRFVPTLMDDTTRIMNAQKARGVDFGEGSIVQKVKAMIPILIPLFATSLKRADSL
                     AIAMEARGYQGGKGRSQYRQLKWTLKDTLTILVILVLGCCLFFLKS"
     gene            37335..38153
                     /gene="mreC"
                     /locus_tag="VQ865_000743"
     CDS             37335..38153
                     /gene="mreC"
                     /locus_tag="VQ865_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001078980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HET3135128.1"
                     /translation="MNRFKKSKYVIIVFVTVLLVSALLATTYSSTIVTKLGDGISLVD
                     RVVQKPFQWFDSVKSDLAHLTRTYNENESLKKQLYQLEVKSNEVESLKTENEQLRQLL
                     DMKSKLQATKTLAADVIMRSPVSWKQELTLDAGRSKGASENMLAIANGGLIGSVSKVE
                     ENSTIVNLLTNTENADKISVKIQHGSTTIYGIIIGYDKENDVLKISQLNSNSDISAGD
                     KVTTGGLGNFNVADIPVGEVVATTHSTDYLTREVTVKLSADTHNVDVIELVGNS"
     gene            38153..38647
                     /gene="mreD"
                     /locus_tag="VQ865_000744"
     CDS             38153..38647
                     /gene="mreD"
                     /locus_tag="VQ865_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HET3135129.1"
                     /translation="MRQLKRVGVFLLLPFFVLIDAHISQLLGSFFPHVHLASHFLFLF
                     LLFETIEVSEYLYLVYCFVIGLVYDVYFFHLIGITTLLFILLGAFLHKLNSVILLNRW
                     TRMLAMIVLTFLFEMGSYLLAFMVGLTVDSMSIFIVYSLVPTMILNFLWITVFQFIFE
                     KYYL"
     gene            38741..39919
                     /locus_tag="VQ865_000745"
     CDS             38741..39919
                     /locus_tag="VQ865_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3135130.1"
                     /translation="MKKKILASLLLSTVMVSQVAVLTTAHAETTDDKIAAQDNKISNL
                     TAQQQEAQKQVDQIQEQVSAIQAEQSNLQAENDRLQAESKKLEGEITELSKNIVSRNQ
                     SLEKQARSAQTNGAVTSYINTIVNSKSITEAISRVAAMSEIVSANNKMLEQQKADKKA
                     ISEKQVANNDAINTVIANQQKLADDAQALTTKQAELKAAELSLAAEKATAEGEKASLL
                     EQKAAAEAEARAAAVAEAAYKEKRASQQQSVLASANTNLTAQVQAVSESAAAPVRAKV
                     RPTYSTNASSYPIGECTWGVKTLAPWAGDYWGNGAQWATSAAAAGFRTGSTPQVGAIA
                     CWNDGGYGHVAVVTAVESTTRIQVSESNYAGNRTIGNHRGWFNPTTTSEGFVTYIYAD
                     "
     gene            40143..40922
                     /gene="rpsB"
                     /locus_tag="VQ865_000746"
     CDS             40143..40922
                     /gene="rpsB"
                     /locus_tag="VQ865_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HET3135131.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMAKYIFTERNGIHVIDLQ
                     QTVKYADQAYDFMRDAAANDAVVLFVGTKKQAADAVAEEAVRSGQYFINHRWLGGTLT
                     NWGTIQKRIARLKEIKRMEEDGTFEVLPKKEVALLNKQRARLEKFLGGIEDMPRIPDV
                     MYVVDPHKEQIAVKEAKKLGIPVVAMVDTNTDPDDIDVIIPANDDAIRAVKLITAKLA
                     DAIIEGRQGEDAVAVEAEFAASETQADSIEEIVEVVEGDNA"
     gene            41001..42041
                     /locus_tag="VQ865_000747"
     CDS             41001..42041
                     /locus_tag="VQ865_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003053075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HET3135132.1"
                     /translation="MAEITAKLVKELREKSGAGVMDAKKALVETDGDIEKAIELLREK
                     GMAKAAKKADRVAAEGLTGVYVNGNVAAVIEVNAETDFVAKNAQFVELVNTTAKVIAE
                     GKPANNEEALALIMPSGETLEAAYVSATATIGEKISFRRFALIEKTDAQHFGAYQHNG
                     GRIGVISVVEGGDEALAKQLSMHIAAMKPTVLSYKELDEQFVKDELAQLNHVIDQDNE
                     SRAMVNKPALPHLKYGSKAQLTDDVIAQAEADIKAELAAEGKPEKIWDKIIPGKMDRF
                     MLDNTKVDQAYTLLAQVYIMDDSKTVEAYLESVNASVVEFARFEVGEGIEKAANDFEA
                     EVAATMAAALNN"
     gene            42287..42574
                     /gene="tnpB"
                     /locus_tag="VQ865_000748"
     CDS             42287..42574
                     /gene="tnpB"
                     /locus_tag="VQ865_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3135133.1"
                     /translation="MMIQLSDLGQVHIVCGKTDMRQGIDSLAYVVKTHFELDSFSGQV
                     FLFCGGRKDRFKVLYWDGQGFWLLYKRFENGKLTWLSTEKDVKALAPEQVD"
     gene            complement(42765..>42874)
                     /locus_tag="VQ865_000749"
     CDS             complement(42765..>42874)
                     /locus_tag="VQ865_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3135134.1"
                     /translation="NKAFRTLEDVIQGLEKEVIKSIVNRRRTRMLFESR"
BASE COUNT        13430 a         7401 c         7899 g        14144 t
ORIGIN      
        1 agcctctctc agggttattt ttcgtcattc atttttgact ttacttcatc ataggatagt
       61 gcatgagatt cctcttctac tgcttcaggc atctttcctg tttcgtaaag agctttaatt
      121 tgtgtactat ccaatgtttc gtatttcaat aatgcttctg caattaactt gtgaatttca
      181 cgatttgact gaataatttc agcagcttta tttcgtgcct catttaataa tgaacgaacc
      241 tcttcatcaa tttcataagc tgtttgttct gaaattgatt tttgaggact ctgtgcacca
      301 aacatagcat ggtttccttc atattgtact gggccaagtt tttcactcat accgtactct
      361 gtaaccattg cacgcgccat ttgtgtcgct tgttcaaagt cgtttgaagc tcctgtagtt
      421 tggacattaa agataatttc ttcagctaca cgtccaccca ttaagccagc caattgctct
      481 ttcatatctt ctttagatag aagcatttga tcctctttag gaagtgcaat catgtatccg
      541 cctgcacggc cgcgtggtac aattgtaacc ttatggacaa cgcgagcatt cgacaagact
      601 agaccaacaa tggtatgtcc tgcctcatgg taagcaacca attctcgttc tttttgtgaa
      661 actgtcttat ctttcttaga aggtccagca ataactctat cttctgcttc atcaatatct
      721 gaagcatcaa ttatcgattt attgcgacga gcagcaacta aagctgcttc attcaagaca
      781 ttctctaaat cagcaccaac aaagcctgga gtttgttgag ccactaattt caaatcaaca
      841 tcttctgcta aaggcttgtt cttagcgtga actttcaaga ttgcttcacg acctttaaca
      901 tcaggacgac caaccaatac ttttctatca aaacgtcctg gacgcaaaag ggcaggatca
      961 agtacatctg aacggtttgt cgcagcgatg acgataatcc cttcatttcc ctcaaaacca
     1021 tccatctcaa tcaaaagttg gttcaaggtt tgttcacgtt cgtcattacc tccgccgaga
     1081 ccgactccac gttgacgtcc aacagcatca atttcatcga taaagatgat agctggtgct
     1141 gcttttttgg catcctcaaa aagagagcga acacgactag ctccaactcc gacaaacatt
     1201 tctacaaagt cagaacctga gatactaaag aatggaacac ctgcttctcc agcgactgcc
     1261 ttagcaagca aagttttacc tgtccccgga ggtccctcca aaagaacacc tgctggaata
     1321 cgggctccaa gttttgtgaa tcgttttgga tcttttaaga actcaacaac ttcaactagt
     1381 tcttgttttt cttcctcagc tccagcaaca tctgaaaatc ttactttaat atcttcttta
     1441 tttgctgctt tagccttact acgtccaaaa ctcattggat tacggccatt gcctcctccc
     1501 atatttccca tcatagagaa taggaagaag aatagaattc caaatggcac aatggatacg
     1561 agtagattaa tccatatacc acttgaactt tcatgcttaa cagttacttc tgctttatgg
     1621 tcagtagcaa gtttttgcaa ttctgatacg gtagtatctg caggaagaat agtgctggta
     1681 aatttctcta ccttagtaac agatggcgtg aaaaactgaa tacctgtttc ttctttactt
     1741 gttttaggat ttttatagac accagaaact tcgataacac taccatttgg ttggtaagtt
     1801 aattctttta cattaccatc ggtaatttct tgtaccaact cagtatagtt gatttgctga
     1861 cttcctcctg agttattccc agaatagaaa tactggaatc ctgtcacaag gaaaaagata
     1921 aataataacc atagaaaagg atttttaatt aaaccattat tttgtttttt cattaaagat
     1981 tattctttct aatttgaata cacttcctct ttcaatactc caatataagg aagattacga
     2041 taattttctt tgtagtctaa accataacct actacaaact catttgggat agtaaagcag
     2101 gtatagtctg cctcaatttc tacaacacgt ccttctggtt tatccaacaa ggttgcaatt
     2161 ttaacagaag ctgcttctct tgctttaaac atatctcgca aattcttcaa agtttgacct
     2221 gtatcaatga tatcttctac aaatagaaca tgtcttcctt tgatatcttg agtcacatct
     2281 tgtttaatat tgataacacc actacttgct gttccaccat ggtagctaga aaccatcatg
     2341 aagtccattt caatatgtgt atcaatatgt ttgaccaatt cagccataaa aggaatagat
     2401 ccttttaaaa tcccaactaa gattggattt tttcctgcat agtctttagt taattgagca
     2461 cctagttttt tagctgcttc tgtaatttca tcgtgtgaaa cgaggacttt tttaatatcg
     2521 ttttctaaca ttttttacct atctattttt tctatataaa gtacagtgtt cattatatca
     2581 tttttcgttt ttttactcaa attattggtc gcaattccca aaattgagac aatttcacca
     2641 aattgctcaa taataagagc agagtttctc ttttccatag ggattttcaa atcaataaat
     2701 aaacgtctga gtttttttct atgcccattt tgaatcaaaa catctcctgt ttttcgatga
     2761 cgaatgtgta tggatgtttc acgtgaaaca ggtatttgtt gaattgattc accttctaat
     2821 ggaagtccaa aggaaaataa atatccttga taagctacct gattttgata gtgtaacaca
     2881 agttcatctt cctcttcatc agcctgcgga ctgattttac aaatctgaaa ctgttggtac
     2941 tcttttatca attcatagcc atttttaatc ggatgacgat actggctttt agattttaaa
     3001 atctgctgaa cttcagcaaa ctgagctttt gtaagattca aatctggaaa acgattcaga
     3061 taagtttgaa gtaaaactct ttgtgtagac tcagagtaag aaaataactg ctgtaaatct
     3121 tccacattaa tattgttaga taattcagct attgccaaat cataatctaa aatttcattg
     3181 ccaatgccta agattgcatc cctaaatcga ggattttctt tttccaattc tggtaagtaa
     3241 gagtttcgaa tacgatttcg aaaataatga ttctcctgat ttgatgtatc ttcaaagtga
     3301 aaaattgatg gaaagtcttt tttctgaaaa tgcaagaagg gacgaatgat ttctatctct
     3361 ccgactactt gcttctcctt aattcctgat agatagcgca agcgagttcc tcgaatcaag
     3421 cgcatcaaaa tcgtttccac ctgatcatca gcatggtggg cagtgactaa agctgtcgca
     3481 cctgtctttt tcatgacctc ttgaaaaaaa tcataacgaa aatttcgtgc acgcgcttct
     3541 gaaaattctc ctgaaaaatt gctgatataa ataggaagct ctgcttcagc agccaacttc
     3601 cttaattcct tttcttccca atctgattca attctctgct tatgattcac atgagctaga
     3661 atcaattcaa tctctaactc tttttgataa gtagacaata ccttaaatag aaacatggaa
     3721 tctaatccac cagaaagagc tagaaccgcc ttagcatgct ttttgaaata tcccttcttg
     3781 agaaaatgat ttaaaaaatc tggttccctc attttagaac ctcataaaca tccttggcta
     3841 tcttagaaat cgtatcataa tcagaattct tagtgaaaat agaaagaata aatggagaat
     3901 ctgcatagac aacacccgta tcatgcttaa attcatccgc atctccaatt ttatgagcta
     3961 ctttaacaga aacacctttg gcaattcgct gactatcaaa atctgtttta gtcaaagact
     4021 ctaacacaaa tccattttga ttataaatag cttccataaa cttcccggcc atcttagaag
     4081 aaatcaattt ttcttttgga tcccaatcat ctcccataat ggcagacatc ttggatttga
     4141 atgtggcatc agattggttt gaaatgtaat atcccaatag attatgagct acattatcag
     4201 attcttttga tactttcgta attaaatcct ttaaagaata ttctttatta tcttcttttt
     4261 taggaagact accacttccc tctggtttat aagaacctgg aaaatcattg actgcagata
     4321 cgtattttac agtcgtatct aactgataaa gaccctcatt tattttttct tgcgtataat
     4381 agagataaga gagtttcaaa acgctggctg catacatctt ttcatcttga ttgataccag
     4441 cttcttttcc agtagtcagt tgcttaacat aaatagagaa agaatctttc tgatattttt
     4501 cagataacat ttcttgaact ttactcatcc gattatcttc ttcagaagtt gattctttag
     4561 ctacccatcc agcctgatca atatgtagaa attctcttcc ttctacaaac atggtcttgt
     4621 cgattgatac ttgcgaataa gctgataagg atgatttcac ttcttttaaa tcataaggac
     4681 tattgtacag tttaaagtca gattctaacc atgctttttt tattgttgga gttacctctg
     4741 attgatcata taaaaatcgt ttgtccgcag ctataaattg atgatttgat agcttaaata
     4801 ctggaattcc ttgtttattt aagcgccact cggttatttg aaaacttgtt ttgggagtca
     4861 atttcccaga ttccactact aaatcttcat tcgcataaac aggaacctct ccataaacca
     4921 tgggagaact taatttttct ctaaaataaa taccaaagtc agattgtgaa aggtaataaa
     4981 tttctttcga agtatagacg acttcttttt ctgtactaac gacttttgaa atggtcaaaa
     5041 aacttggtag caacaaaata attaagaatt tacgcattct tcctttcctt ttcttcttgt
     5101 aaacgcaata attgattttt atcagccaat tcttccagct tttcatctga caaactcaaa
     5161 aattgctcta ttacgtctaa taaattttcc attttatcac ctttgaagca agtcaggaat
     5221 cgtataaact ttttccctcg acttagaata atagtacttc gctcgtgtat atttggcagc
     5281 ataatcttca tctttcaact tggtagcaaa tgctgtctcc ttatcctttt catcactcaa
     5341 agtttgatac tgagtttgca agtctgctaa ttgctgacgt ctttggagta attgctgata
     5401 actctgcgct aaattaaaag ttggcaagat aaataatagc ataatcaaaa tcaatacccc
     5461 tcccataaaa cgattccgtt tttgtcgttc tttcatcagg tagcgacgac gttggtattc
     5521 attttgaata aaagaattat tcaattgtac aatattttta gacattttct tctacccgtg
     5581 tttcactgat aatttcatac attcctgctg catcttcttt ttttgtacta tctttcatct
     5641 ctagtacttt tacaagcagc aacttattgc caaagcgaat ttcaacttgg tcattaactt
     5701 tcaagtccgt tgaacttttg gccaagattc cattaacctt gattctacct ttatctgcta
     5761 cttcctttgc gactgtacga cgcttgataa ttcgcgatac ttttaaatat ttatctaatc
     5821 tcatccttat tacctcaatt tattattgta ccatttttat ctattttata gaagaaaaat
     5881 atcaaatgga attttcttcc ttagactctt ttatctctaa taaactttct ccaaaaatca
     5941 gcagaccttc taaaatttca taatctttct tattttggac atcaaataca agctccatta
     6001 atcccttatt ctcagcgatg cctgctttta agttcgttac ggataaagct ttaaaataat
     6061 cttgagctaa aaacaatcgt tgagtgactt tttcaaattg aattgtaatt ttattatctt
     6121 ttctttccac acgttgaaca aagaccttgt ccaagtatga tttaaccaaa ccaatctcta
     6181 aaagataggc tactacatct gggtattctc caaaacggtc tatcaactcc tcttgtaact
     6241 cttcataatt gacacggttg tcaatttgac gaattttctt gtaaatttca atcttatgtc
     6301 gttgatcaga aatataagta tcaggaagat aggcatcaat ttgcaaaatc aactcagcat
     6361 tccctttggt tcttgtgtta gcgttagcat taccgtttcg tttagcaata gcttcctcta
     6421 ataactgcga atacaattca aaaccaacag aatcaatgaa accagactgg gattttccta
     6481 aaagatttcc tgctccacga atcgaaagat ctcgcattgc aatcttaaag ccagagccca
     6541 attctgtaaa tcctttaatc gcttctaatc tcttttcaga gacttcactg attgattttt
     6601 ctggacgata catgagataa gcataagcaa tacgattact acgaccgact cttcctctta
     6661 actgatataa ggttgacaag cccatatggt ccgcattttc aataaataaa gtattagcat
     6721 ttggaatgtc cacccctgtc tcaataatag tagtcgtcac caagatatcg tattgtccct
     6781 caataaagtc taatagagta ttttccaact ggacttcact cattcgacca tgaacatatc
     6841 caatcgaagc ctctggaatc aactcctgta attctgaaac cttctgaaca attgtatcaa
     6901 ctttgttgta aagataataa acttgacctc cacgctccat ttcacgcaag acagcatcac
     6961 gaatgacact atcattcttt tccaaaacat aggtctgaac aggatagcga ttagtcggcg
     7021 gagtttcaat aacagacaaa tctctgattc ccagcataga catatggagg gtacgaggga
     7081 ttggcgtagc ggtcaaggtt aggacatcca cttgtttctt cagttctttc aaagtttcct
     7141 tatgcttgac accaaatcgc tgttcctcat caataatcat caagcccaaa tcagcaaaca
     7201 caacatcttt tgacaaaaca cgatgtgttc caatcaaaat atcgacttga ccgtttttca
     7261 atttttcaag tgttgcagtc tgctcttttt tacttctaaa gcgactcaac acatcaacat
     7321 taactgcaaa attttggaat cgttccttaa aattcgtata gtgctgttgc gctaaaaccg
     7381 tcgtcggaac tagaatgaca acctgtttgt gatcattgac tgctttaaag gctgcacgca
     7441 tagcaacttc agtctttcca aaaccaacat ccccaactaa aagtctatcc attggctgag
     7501 aagcctgcat atccctcttg atttcctcaa tactacgaag ttggtcatcc gtttcaacat
     7561 aagggaaagc atcatcaaag gcatcttgat catcatcatc agctgagaaa gcaaaaccct
     7621 tcaactgact acgttcagag tagagtttga ttaaatcatc agctatatcc tctacctggt
     7681 tcttaacctt ttgcttggcc tttttaaaat gaccgtcatt taatttattg agttttggag
     7741 ctttaccatc acttgaaata tatttggaca gtagatgaat ctgttccacg ggaatagaaa
     7801 tttgatcacc attttggtat tggacactga cataatcacg atgaattccc ttgatttcaa
     7861 tggtttcaat tcctagatat tgaccaatcc catggatatg atggacaaca tagtcccctt
     7921 tttcaagttc attgtaatct tttaatctct ctgcatttga aacatgttgt cttcgaaaac
     7981 gacgctttaa tttcttttga aaaatctcat gttcagttat caataaaatc ttttcatcta
     8041 caaaatgaaa accatgtctg agattacctt ctattaagtt tacagattct ttacagatac
     8101 ttgtcttatc tctagaatcc aatttaatct gatattcctc taacatatcc tccaatgttt
     8161 tacttcccat tgaattgcta gactgcagaa taatggtgta atccattttt ttatatcgtt
     8221 caatttcttc ttttagaaaa gaaaactgat tgaaaaattc ctgcatagga tattgattga
     8281 attgataaat tttgtcaaat ttgagatttc ctaaaccctt ttgaagatta gagaaaaagg
     8341 tcactggact ttgtttttta tagatttgtt caatatcaga aaaatactgc atatcagaaa
     8401 atgctttact attctgtaat tcttctgtaa agtactgcgc taattctctt tcaaagactt
     8461 catactgatt catcaatttt tgataatcat caaagaatat tggagtatct ttttcaatat
     8521 aatcaaagac agtccatgtc ttatcatagc acaaagataa aaacttccga gaatctgcat
     8581 gactttgctt ttgatgaaaa cttgaaagaa tttcttctag gtatgatttc aaaataggtg
     8641 ataaagtttt tgaaatttgt ttttctaaag ctgactgtcc tcgttgataa tccttttctc
     8701 tcaaaagcat atcactagct ggaaagatag tgagttctgt cttattttct ttcgataatt
     8761 gtgtttctac ttcaaatgac ctgataccat caatttcatc accaaaaaac tcaattcgac
     8821 aaggttctaa ctgggatatt tcaaaaatat ctaaaatatc tcctcgaaga ctaaattcac
     8881 cctgagtttg tacttgagta acttttcgat agccattttc ctttaactga tggataaacg
     8941 cgtgttgagc atattcttca ccaactgaga tttttacaat actatctttg aatgcattgg
     9001 gagacggtaa aatcaatcga cttgctgcga tattacaaac taaaatccct ttcttagatg
     9061 aatcagtcaa aaaacgcaag gcttcaaccc gtgaaataat tttttcctgt gaagacatca
     9121 aaaactccac cataggagca tcatctacca aaaatggata gacgagttcc tcacccaaga
     9181 tagaaataag atcactaaca agtccttctg cttctccata agttgacgtc aataacacaa
     9241 tcctatcttc tttttctaaa ctgcttgcaa ttgcaagagc cttagtagat gttgataaac
     9301 caagtattag ttgtcttttc ttatctgtta aattttgatg ccatttttta atctgatcat
     9361 tttctgagaa taaatctaat aaggtcacca tttatccgtt atacctctgc attgttttct
     9421 caaaattttt ctcttgtaaa tagtagttta cagaatcgtc aactttgtca acagactgta
     9481 aaataccgat ataatcatcc ctgtcaaact tactcaaaac atgatgaaca actgacatac
     9541 catttttagg tcttccaatt ccaatcttaa cacggttaaa gacctgagtt cctatatgtt
     9601 gaataataga cttgatacca ttatgaccac ctgctgagcc ttttgctctt aaacgaattt
     9661 tcccaacttc catgtcaaga tcatcgtaaa tgataagtaa atcgtcaata tccaaaccat
     9721 agtaagttaa taaagcatga actgcttttc cactttcatt cataaaggtc gttggtttaa
     9781 ccagataaat tttttctcca tttaggaaaa aggatgctag gtcagcttga aatatcttat
     9841 cgtgtgtaaa agtgacattc tgtttcttcg ctagttgatc aatcaacata aaaccaacat
     9901 tgtgttttgt ttcaaaatat ttatcccctg gatttcccaa gcctacaagt aatttggtca
     9961 tttatttttc ctttcaaaag ccaaaagggt tggaattttt ttccaaccta attgacacca
    10021 tttattaatt tttagacatt aaagcggaat tccatgatat cgccatcttg aacgatatat
    10081 tcttttcctt cttcacgcaa gcgtccagct tcttttacgg ccttttcaga tccgtatttc
    10141 actagatctt catatgacat ggttactgca cgaataaagc ctttttcaaa gtctgagtgg
    10201 ataataccag ctgcttgagg agccttcata ccacgtttga aagtccaagc gcgaacttct
    10261 ttttcaccag ctgtgaagta agttcccaat ccaagcaagt ggtaagctgc acgcgtcaac
    10321 ttatctacac ctgattctgt caaaccaatg gcttcaagaa actctttttt atcttcatca
    10381 tccaattcag aaatttcttc ctcagcacgc gcagaaataa cgactacttc agcattttct
    10441 gtcgctgcaa attcacgaat ttgtttgaca tagtcgatag agtcaggttc cgaaaccaca
    10501 tcctcatcca cattagctac ataaagaact ggtttagtcg tcaaaaggaa aagacctttg
    10561 acaacctttt gttcctcatc tgtaaattca atggtacgag ctgatttccc atcttctagg
    10621 actggtttaa tcttttgaag aacattgaat tctgctactg attctttatc tttttgcgta
    10681 cgtgccatct tttctacacg cgcatatcgt ttgttcactg attctaagtc agcaagaatc
    10741 aattccagat taatggtatc aatatctgca agcggatcta caaaggcgtc ttcacgtcct
    10801 tgctcgcgca tcacattttc atcatcaaaa gcacgaacta cgtgaacaat cgcatctact
    10861 tcacgaatat tggccaagaa tttattccct agcccctctc cttttgaagc tccttttaca
    10921 atccctgcaa tatctgtaaa ttcaaatgtt gtgggaactg tctttttagg agttatcatt
    10981 tcagttagtt tttgtagacg ttcatctgga acttccacca ttccaacatt tggatcaatc
    11041 gtcgcaaatg ggtagtttgc tgcctctgct cctgcttttg taattgcatt aaatagtgtt
    11101 gatttaccaa cgtttggcaa accaacgata cctgctgtca aagccatatt tctcattctc
    11161 cgttttcatt tcaatcccta atattataac acaaaaaggg ataaagtgct aaccctctaa
    11221 ctaagggttc tcagtcaata attttattca tttttcgctc aaaatcatat cgccccatca
    11281 tgacaacatg ctcacaatta ctgcatttta ttttgatatc tgctcctaca cgtgtaattt
    11341 cccaacgatt agccttttta ccagtcgact tgattgtaca agcgtgtggt tttttcatct
    11401 caacaaaatt tccaacttga tacatactac tctccttttc tttttcgatt atatcataaa
    11461 agaggcgagc caggctcaac ctctttcact taatttgtac gaactggtgt aatgagctgc
    11521 atgaagtctt cgtcagtatc tgctggcaca agagtaaatg gacgaacagc tgagataaag
    11581 ctaatggtca ccttttcgct atttaaagct ttaagagaat caatcaagta agttgggttg
    11641 aaactaatgg tcaaatcttc accagtaacc tgatcagtat cgatttcttc gtttacttta
    11701 ccaacttctg gagagtgaac atgggcgcta acaaccccat ccttaatttc aagtttcaca
    11761 gtaccatttt gagtcgcact tgataaaaga cgggcacgct ccattgactg gcgtaagttt
    11821 accacattaa aagtaatagt agtgttaaag tctgttggaa tcaagcgatc tgtatcagga
    11881 tagtttcctt ctaggagacg agtatagaag ctaatatttt cgcttctaaa gaggatttgg
    11941 ttattggcaa agaaaatctc tacagtttcg atatcatctg taaataccgc tgaaaattcg
    12001 cgtagagaac ggctaggaat tacgacatca aaatcatcac tatttttttc aagagtcaat
    12061 tttttctggc ttaggcgatg agagtctgtt gcaactgttt ttaactcttt gtgttgactc
    12121 aatacgaagt ggacacctgt taaaatcgga cgactctctt gtgtacttgc agcaaaggct
    12181 gtttcattaa taattttctt gagtaatttt gtttcaagta ttaaaggagt gcttgctgaa
    12241 atttcttgga ttcgtggata ttgttcgcta tcttttcctt ttagggtaat ttctgatttg
    12301 ccactggtta aaacaatttg attttgttca atttctttaa aatcaagagt tacatcaggt
    12361 aaactagata ctacattgat aaagaaagaa gcttcaagaa ggatcgaacc taaagaagta
    12421 atcaacaaac cagcatcttc atttttttga gaaataaaat tttcaattga gatttgacca
    12481 tttgaaccaa ttaaagtaat accttcattg gtcacgtcaa tttttactgt tgataaaata
    12541 ggaatggcat ttttagaact aatagctctc ttagtagtat ttaatgcttg tagaaataaa
    12601 tttttattaa ttgaaaaatg aatcatggat tctcctttat ttatttttag tattagaaag
    12661 ataatagtaa taatagagtc tgtgaaatct gtggaaaaca gcctttaaac aagtcctatc
    12721 aagtttttta gcttgtttaa aaaatgtgga taaaaaagat aaaaaactaa aagttatcca
    12781 caaattattt gattttcttt ttgattgatt caatttctaa acgtaaatta tcgtcttgat
    12841 caatcaaaga ttttattttg gcatgggcat gaatgactgt ggtatgatct tttcccccaa
    12901 attccttccc aatttttgga agactattat ctgttagttc tctagataaa tacatggcta
    12961 cttgacgggc caaaacaata ttttgaaggc gtctacttcc cttcatttct ttgatactaa
    13021 caccataaaa gttaccaact tcagtttgga ttttatcaat tgggatgacg agcatttggc
    13081 taacatcttg tttgcgggct ctaatggctt ctgcagcaat atcaatagtg atatccttga
    13141 ttttttttac tctggcaatt aaagtgatgt cgttgatggc tccctcaaga tctcgaacat
    13201 ttgaatcaaa ttgcccagct aggtattcta gagtatcact ttggaaattg tagcctaaat
    13261 gttccgtttt actttgtaaa atggcaatac gtgtttcaaa gtcagggggt gtgatagttt
    13321 gtgtcaatcc ccaactaaaa cgcgtgacaa gcctctcctc gagcccttct agatgttttg
    13381 gactacgatc actcgttagg acaatctgtt tttgcttgtc atgaagggcg ttaaaggtat
    13441 tgaaaaattc ttcctgagtt gcgacttttt ttccgctgag tgactggata tcatcgatta
    13501 acaaaagatc aagactacga taggtctttt taaacttttc catttcccca agtcttaggt
    13561 gatcaagaaa gtcattaata aagctttcgg cagggatata tttaacacgc gcattaggaa
    13621 tattttttag aatttcattt ccaatagcgt ttaataagtg agtcttacca aggcctggtc
    13681 ctccatagat aaaaagaggg ttataggtca gagccaaatc ttcagagaca gctaaagcgg
    13741 ctgatacagc ccaaacattt ccatcccctt gaataaagtt atcaaaggta tacttttctt
    13801 ttaatcccgt atctgaataa ggaatagata ctaactttgg actatagtca taaagagtta
    13861 aatttgtagc ttcttcaact tgtgagctag tcgtatcttg aggtttggtg aaaatatagt
    13921 ggggagttat ttcagcgtca taaatttcaa aaccagctac tacaataata tcttttagtt
    13981 gtttttccca gaccatttcc atttcagagc gaggtagaaa tatagtggca acattttcct
    14041 ctaccttgat aacttcagct tgaatagcat agaaatcata catggatcga gtcagtcttt
    14101 cttgtgcaaa ttctaatata cgattccaaa attgtttttc tttcaatcct ttctcctcct
    14161 ttactattta aaagtttaat actagagata ttttaccata gatagcaaga attttccaca
    14221 agctgtgaaa aataatccac aatgttacca aactttatcc acaggttggg gataaaagaa
    14281 gaaattattg atttattaag ctttttatcg aaaaacatag tggataacct tgtgagataa
    14341 aaaaataaaa gaacagcctt atttcaggct gttgataatt ctactatatt cttcttgatt
    14401 tgaaaaagaa ataatgattt ttccactgtc ttttttagat agtttaattt ctacatctaa
    14461 tccgagtagt tttcttaact gtttttcttc attttgtatg aaatgattag ttttttgctg
    14521 tttcttttgt tttttctctg tcagaagagc ttctaatttc cttacagaaa tatcttcttc
    14581 tataatccgt tgaaagaaat agtcttgttg ttccttattt aacccaacta gggaacgcgc
    14641 atgggcttgt gatagtttgc cattttctac ttctgaaaga atctgttctg gcaaggaaag
    14701 taaacgaatg gagttgctga tatatggacg agacttgccc atcttatctg caatttcagc
    14761 atgggtgaat cctttctcta cgagagattc ataggcgcgt gcttcttcta ttgggtttaa
    14821 attttctctc tgtaaatttt caataatgga ctggaccatc atctcttggt ctgaaatctg
    14881 tttaacaaca gctgggatag accgtagacc agctaaaagt gaagcccgat agcgtctctc
    14941 tcctgcaagg atttcataac caataacagg agattgacga acaataatcg gttgaatgac
    15001 cccattttct ttgatagact gtgctagttc atctagtttt tctctatcaa attcttttcg
    15061 gggttgatag ggattttttt gtatatctgt gatagaaatc atttcaaatt tttccatgat
    15121 tctacactaa cacatctttt ctcttatgta aagctttctt tacatagatg tcaattaaga
    15181 ttctaaatca cctgaactct tgttaagttt gatagaggta gtttcttctt tcccgttacg
    15241 atagtaggtt atcttaatgg tgtctccgat agaatggttg taaagagcac tttgtaagtc
    15301 tgttgatgaa gcaatctctt tgtcatctac ttttgtaatt acatcgtatt tttcaaggtg
    15361 accattggca ggcatattac tttgtaccga acgaacaatt acaccagatg taacattact
    15421 tggaatattg agtcttctga tgtcgcttgt actcacatta gataaattaa ccatctggat
    15481 tcccaaagct ggacgcgtca cttttccgtt tttttctaac tgttcaataa tattgatagc
    15541 atcatttgca ggaattgcga aaccaagacc ttctacagat gttcctccat ttgtagcaat
    15601 tttacttgag gtaattccga taacctgccc ttgaatattg atcagtgggc cgccagagtt
    15661 acctgggtta atagcagtat cagtttggat ggcttttgta gaaatagctt gtccatcttc
    15721 cgattttaag gatacatttc tattgagact ggatacgata ccttgagtga cagtatttgc
    15781 atattcagaa cctaacgggc taccgatggc aatagcagtt tctcctacag ttaacttact
    15841 agaatcacca aactcagcta ctgttgtcac tttttctgaa gagattttga cgacagcaat
    15901 atcagagaaa gtgtcagctc cgacaatttt tccaggtact ttagtcccat ctgacaatcg
    15961 aatatctact ttgctggcgc catttataac gtgattgttg gtgacgatgt aagcttcttt
    16021 atcattcttt ttataaataa ctccagatcc ttcactagag attcgctgag aatctgtgtc
    16081 agtatcatca ttgccaaata cgctattttg tctgtttgcc gaataagtaa taacagaaac
    16141 aacagcatct tttactttgt taacagcctg tgttgttgaa ttttcgttct tataggcagt
    16201 ttgtgtaata gtactattgt tgttagagtt gtttacacta cttttttgag ttagttgagt
    16261 tattgaaaaa ctacccaagg ctccactaaa aaagctaatg acgataacga ctaataattg
    16321 aaaccatttt ttgtaaaatg tttttagatg tttcatattt gcctccatat gtttgaatta
    16381 ctgaaagtat aaactgacta gcttaattat aacttaaaca caaaagtttt acacaaactg
    16441 tggataactc ttttgaaatt gtgattttct taattgaaat ctatttttta ttttgtgaat
    16501 aagatgtgaa aaaatagaga atatgttaga atagagtcat gaaaattaaa gttgtaacag
    16561 ttgggaaact gaaagaaaag tatttaaaag atggtatcgc agagtattca aaacgaattt
    16621 ctagatttgc taagtttgaa atgattgagt tatcagatga aaaaacacca gataaggcca
    16681 gtgaatcaga aaatcaaaag attttagaaa tagaaggtca gagaatttta tcaaaaattg
    16741 ctgaccgtga tttcgttatt gtgttagcca ttgaagggaa aactttcttc tcagaagaat
    16801 ttagtaagca gttagaagaa acttctataa aaggattttc tactcttact tttattattg
    16861 ggggaagttt aggattgtca tcatctgtaa aaaatagagc caatctttct gtcagttttg
    16921 gtcgcataac cttaccccat cagttaatga gactagttct tgttgaacaa atctatcgcg
    16981 cttttacgat tcagcaggga ttcccctacc ataaatagaa aattgacttt taattgaatt
    17041 tttggtagaa taattgtatt aggtctcata gctcagctgg atagagcatt cgccttctaa
    17101 gcgaacggtc gcaggttcga atcctgctgg gatcaatata atagcaaagc tgggaatttt
    17161 cccggctttt ttcttaaaaa agtacacttt gggagaaaaa aatgacagtt gagagaattt
    17221 tatctaaaac gaaattccat tttgtataat ggtttttgta agttagctta caagaaaaaa
    17281 cattttagga gattttatta tgaaaaacac agttaaattg gaacagtttg tagctttgaa
    17341 ggaaaaagac ttacaaaaga ttaaaggtgg ggagatgagg ttgtcaaaat tcttccgtga
    17401 ttttatttta caaagaaaaa agtaatgaaa taaggggaaa gagtaatgga tttatttgga
    17461 tttgggacgg ttattgttca ttttttaatt attagtcaca gttaccattt tatttgtaaa
    17521 ggtcaaataa atagaaaaga attattcgtt tttggtgctt atacattact aacagaaata
    17581 gtatttgatt ttcccttata tattctatat ttagatgggt tagggattga aagattttta
    17641 tttcctttgg gattatattc ctattttcga tggatgaaac agtatgagag ggatagagga
    17701 ctattcctaa gtttactact atctctttta tatgagagca ctcataactt tctgtccgta
    17761 actttctcct ctataacagg agataatttt gttttacaat atcatttccc attctttttc
    17821 gttgtgacgg tgttaaccta ttttgttaca ttaaaaatca tttactattt ccatttggaa
    17881 ctagcctatt ttgatgagga ctacctttat cctttcttga aaaaagtatt ttttgcttta
    17941 ctattgctac atattgtatc tttcgtttca gatatggtaa gtacgattaa acatttgaat
    18001 agttttggaa gtattttgtc atctattgtc tttatctctc tccttttgac cttctttgca
    18061 atgaattctc ataaagttca aatggagaaa gagattgctt tgaagcagaa gaaatttgaa
    18121 cagaaacatt tacagaatta cacagatgaa attgttggtc tgtataatga aatccgtggt
    18181 tttcgacatg attatgctgg aatgcttgtc agcatgcaga tggcaattga cagtggtaat
    18241 ttacaggaaa ttgacagaat ttacaatgaa gttttagtca aagcaaatca taaattgcgt
    18301 tcagataagt acacttactt tgatttgaac aacatagaag actcagcttt acgaagtttg
    18361 gttgctcagt caattgtcta tgctcgaaat aatggtgtag agtttacact ggaagtaaaa
    18421 gatacgatta ccaagcttcc aattgaacta ttggatttgg ttcgtatcat gagcgtttta
    18481 ttgaataatg ctgtcgaagg atcggctgat agctataaaa agcagatgga agtagcagtt
    18541 attaagatgg aaactgaaac agttattgtg attcagaatt catgtaaaat gacgatgact
    18601 ccttcaggag atctatttgc cttaggattc tccactaagg gaagaaatcg cggagtcgga
    18661 ttaaataatg tgaaagaact actagataag tacaacaata ttattttaga aacagagatg
    18721 gaaggcagta catttagaca aatcattaga tttaagaggg aatttgaatg aaagttttaa
    18781 ttttagaaga tgttattgaa catcaagtga gactagagag aatattggat gaaatttcga
    18841 aagaatcgaa tattccaata tcatacaaga caacgggaaa agtccgtgaa tttgaagaat
    18901 acattgaaaa tgatgaagta aatcagcttt atttcctaga tatcgatatt catggaattg
    18961 agaaaaaggg atttgaagtg gctcagctca ttcgtcatta caatccttac gctattatcg
    19021 tctttatcac tagtcgatca gagtttgcga ctctaacata taaataccag gtatcagccc
    19081 tagattttgt tgataaggat atcaatgatg agatgtttaa gaagagaatt gagcaaaata
    19141 tcttctacac gaagagtatg ttacttgaaa atgaagatgt tgtagattat ttcgactaca
    19201 attacaaggg aaatgattta aaaattcctt accatgatat tttgtatatt gaaacaacag
    19261 gggtatctca taaattgcgc attattggta agaattttgc aaaagagttt tatggtacca
    19321 tgacagatat tcaggaaaag gacaaacata ctcagcgatt ttattctcct cacaagtcat
    19381 ttttggtaaa tataggcaat atcagagaaa ttgatcgaaa aaacttagaa attgttttct
    19441 atgaagacca tcgttgtcct atttcaagat taaaaattag aaaattaaaa gatattttag
    19501 agaaaaaatc tcaaaagtga ttgacaatta gcaagaaatt gatataatgg ttatatctgc
    19561 tacagataga aggtccgttg gtcaaggggt taagacaccg ccttttcacg gcggtaacac
    19621 gggttcgaat cccgtacgga ctattttatc cgccatagct cagttggtag tagcgcatga
    19681 ctgttaatca tgatgtcgta ggttcgagtc ctactggcgg agtatagata aaagggaaca
    19741 cagctgtgtt cctctttttg tatcaatttg tatcaccaag cattttcata aggaagtctg
    19801 ttatttcttg agaactttct ttttttccat gtgcaatcca agtttggcag acaccaaaaa
    19861 gtgcatgagt tagatagatg ctactatatt ctaattcggt ggtatttaga ttcagttgca
    19921 taaatcgctt ttgtaaatct gtactaagca tgatatgaag tttatttcgt aagaaatttt
    19981 ggatttcttt agtcccattt tcagaaagaa gggcagccag aagtggttct gactctagat
    20041 attcaaaaac ttctaaaata gcgtctcttt tgtgatgagc atgtttttga aaaatatatt
    20101 caaatgtatg gaatagcttg ctttgatagt gctcaatcat atcatactta tccttatagt
    20161 gagtatagaa gctggaacga ctaattccgg ctttttctac taatttgaca gtagaaattt
    20221 tatcaaatgg ctgttccatc agtaattgta ccatagcatt ttcaatagtt cgctttgttt
    20281 ttaagcgttt gttactttct tgcatatttc ctccttgtaa acaaattaga ctatatgtct
    20341 aaaaatagat tttttatctt gtaatttaga ttttttaatg tataatctat tatatcaaaa
    20401 ttttagacaa tatgtttaaa aaaggagaaa ctaagtttaa agaatggaaa gcaatttaaa
    20461 aaaaaccaac ctttattatt gtcatgatcg ggatttctct tattccagat ctgtacaata
    20521 tcatattttt gtcatcaatg tgggatccat atgggcaatt gtctgactta cctgtggcag
    20581 ttgtaaataa tgataaagag gcttcctata atggtaatac tatggcaata ggaaaagaca
    20641 tggtgtccaa tttaaaagaa aataaaacct tggattttca ttttgtagat gaagaggaag
    20701 gaaagaaggg attggaagat ggcgattact atatggtagt gactttacca agtgatttat
    20761 ctgaaaaaac aactacatta tccaatattc aatcgacagc agcttatcaa tcattgacaa
    20821 gtgagcaaca aactgagata agtgattctg tatctcaaaa ttcaactgat agtattcaat
    20881 cggctcagtc aattgtagct ttagtacaag atttacaggg aagtttagaa aacttacaaa
    20941 atcaatcttc taatctttcg actttaaaaa atcaatctaa tcaagtatca cctattactt
    21001 ctacttcttt gataggattg tcaagtggat taacagagat acaaggagat gttactagca
    21061 aattagttcc tgccagtcag tcgattgcat caggtgtaaa cgcatatact acaggtgttg
    21121 ataaagtttc tcagggcgca agtcaactaa gtgaaaaaaa tgccaccttg acaggtagtt
    21181 tggataaact agtttcaggc tcaaacacct tgacacaaaa atcttctaga ttgacagcag
    21241 gagttggtta attacaatca ggatctgggc aattagcaga caaatccagt cagttacttt
    21301 caggtgcttc tccattagag aatagagcta ataaattggc agatggatct aggaaactag
    21361 cagaaggtgg aacaaagtta acttctggat tggaagattt acagacagga cttgcttctt
    21421 taggacaagg actaggtaat gctagtgatc aactcaaatc agtatcaaca gaatctaaaa
    21481 atgcagagat tttgtcaaat ccactcaatc tttcaaaaac agacaatgat caagttcctg
    21541 taaatggaat cgcaatagct ccttatatga tatcagttgc tctttttttt gcagcaatat
    21601 caacaaatat gatatttgcg aaattgcctt caggacgtca tccagagagc cgttgggctt
    21661 ggttgaaatc ttgagctgaa ataaatggta ttatagctgt tttggcagga attttggtat
    21721 atggaggagt tcagcttatt ggtttaactg ctaatcatga gatgagaata tttattctca
    21781 tcatcctaac aagtttagta ttcatgtcta tggtgaccac tttagcaacg tggaatagcc
    21841 gtataggagc ttttttctca cttattttgc ttttactaca gttagcatca agtgcaggta
    21901 cttatccact tgctttgaca aatgatttct ttagatctat taatccctgg ttaccaatga
    21961 gctattcagt ttcgggatta cgacaaacaa tctctatcaa caagtcattt tcctagctgt
    22021 catactagct ctatttactg gtttaggtat gctagcctat caacataaga aaatggaaga
    22081 agattaaaaa aatcgaccga ttaactggtc gattttttat gccttagatg actttcgtct
    22141 gtgattatag attccaaata gtaagagaga agtaaaggaa cagattgctc cagtaataaa
    22201 accattggga atgaaggaaa gtgtaatagt tcctttcccc ttgggaatgt caactttcat
    22261 aaatccagtt tgagcttgtt taatttctat tttcttacca tcttggtagg cagaccaacc
    22321 tttgtcataa ggaatggtga agaaaataga tgtatcttgt tggacatcat atgtagcaaa
    22381 aaccttgttt ttagaagttg atactgtgac aggttgttct ttaatttttt gaattgcctc
    22441 ggtgaaagtt ttggtatcta aacgatagaa ggtaggagat tcaaatgata cttgtgaatt
    22501 tccagggaaa ctaacattga tattgaaagt ttttttctct ttagtatatc ctagattaaa
    22561 gaaggagaag acattatcag ttgtaaaagt ctttttttca ccatttacaa ggatgtcaac
    22621 cttcttttgt ttatcgttag aaaagtgaag gtttatgaaa gagagataaa cttggctgtt
    22681 ttctggaact tcaatttgat actggattgc tgcatcttca tttgaagaac ttgtgacact
    22741 aatcaaatca ttagtatttt ctattttttc tgttttttca taaggtattg gagaaaaata
    22801 atcaaaattg acgttagcaa gttgatttaa aaatgaggcc tgattatcca aggtatgttc
    22861 attgaacttg acatcattgt aaacagattg actagcaact gcaatcggaa gagagtattg
    22921 attttcatat agggtaagat tatctttttg atagatatct ttaaagccat acttatcaat
    22981 aggactgtct gagatattgt actggatacc aaataaacta tcagccaaaa tactattatt
    23041 tgcatatcgg agattgagat tagtcccaga ggatttaaaa ccaagtttat ctaaagtaga
    23101 gcttgatgaa cgatttcgaa cagatgaaaa ttgagagatt ccattgtagt tgaatttcat
    23161 actgtcattt cctgtctgag tttgtagttt ttcagtacga gtaaattgat ttccaatata
    23221 tgttgagaaa gattccatag ctaggatatc tcgactataa gcacttcgag aagcaaatcc
    23281 ccattcctta gcaattccgt ccatttgaga tgaagcattt aaactcattt caaccagtat
    23341 aaataaagag attagaatgg caaatagatt cacagatata aactttttga taactgcaag
    23401 gagtaaaaga gaatagacaa ccaaaaattc aagagtaagc agaatattca aatctgttaa
    23461 aaaagaataa tgcgatttta gatagatggt agctaaaaat cctgctacta caagaaaaag
    23521 cgaaactaaa aaattccaga ctttaagttc tttcagacgc tttaagactt ctgctgctgt
    23581 gtaaattaac aaggtagaga aaatccaagc atagcgatgt aaaaacatgt ttggagtatg
    23641 catgccttgc caaaataagt caagagcttc tatgtaaaag cttgcaatta gaaatgcaaa
    23701 gaatattaca tatatgagtt tcacgtgaaa cttaatagat ttcagcgtaa aaaataaaat
    23761 ggtcaaaata aagggaaata gtccaacaaa aatcattggg atggccccat actttgttgt
    23821 gtcaaaggaa ccaatgaatt gcttagcaaa gagatcaaga taccagctac tttcagtttg
    23881 aaactttgta acttcagtca atttttcccc atgtgtctgt aaatcaaata gagtgggaag
    23941 agtcataatc aaactagcca taccagctaa aaaggagata actatgaaat caagaacaga
    24001 tgattttcga gtcttaaagt cccacgaaat ttgacagaga taccagaaaa taagaaacaa
    24061 tactgtcata tatccaaaat aataattttg aataaataag attgacagac ttgtaaagta
    24121 caataggagt ttcttttcag ttatcagtag atgtaaacca gttataatta aaggaatcaa
    24181 gataaaaaca tctagccagg tttttatctc taattgactg acagtgaaac tcatcagagc
    24241 ataggaagta gataaggcta gttttaaagt ctgagggata gattgaaaca atttattcaa
    24301 actaaaaaag gttgacagac caatcaatcc aaattttaag agagtggtca gatagacagc
    24361 atctggcatg ttcgttagat caaaaaagta aactagaggc gcgagaaaac tacccaagta
    24421 ataactagat agggcataga agtttagccc tagaccactt gtaaaggtgt aaaacagact
    24481 actatttcca tgtaggatat ttcgtaaggc tacatcaaaa ataacgtatt gatgaaagcc
    24541 atctcctaat agaggagagt tgtcgctatt ccagtagata ccttgagata gatatactcc
    24601 agacataatc actacaggaa tgatgagaga aataaaatag gttcgatatg tttttaaaaa
    24661 tgatttcatg ttacctcgta gaatgataga aaactcagtt ggttaaccca actgagtttt
    24721 gaagttttat ttagtctttc caaagttctt taacttttgc ttgtacttct gcattttcta
    24781 ggaattcatc gtaggtttca tcgatacggt caatgacgcc atttttagat aagacaatga
    24841 tatggttagc caaagtttga ataaattcgt ggtcatggct agcaaagatg attgattctt
    24901 taaagttttt caatccatca ttcaagcttg agatagattc caagtccaag tgatttgttg
    24961 gatcatcaag tacaaggaca tttgatttta agagcatgag ttttgaaagc atgacacgaa
    25021 ctttttctcc ccctgacaag acatttacag gtttgttaac ttcatctcca gagaagagca
    25081 tacggccgag gaagccacgt aggaaagtat tgtcatcttc ttctttactt gcgaattgac
    25141 gcaaccagtc aagaattgat tctcctcctg caaaatcagc tgagttatct tttggtaggt
    25201 aagattgact agttgtaact ccccacttga cagttccttc atagtcaata tctcccatga
    25261 ttgcacgaat taatgcagtc gtttgaatat cattttgtcc aataagtgct gtcttatcat
    25321 ctggacgcaa gatgaaacta atattatcca agatagtttc accatcaatc tttacagtta
    25381 gattttctac tgtcaagaga tcattaccaa tctcacgttc cgctttaaag ttgataaatg
    25441 gatatttacg actagatggt acaatctctt ctagctcaat cttatcaagc attttcttac
    25501 gtgatgttgc ctgccttgac ttagaagcat tggcagagaa acgagcaacg aattcttgca
    25561 attgtttaat tttttcttct gctttagcat tacggtctgc tagcaattta gcagcaagct
    25621 cagaagattc cttccagaag tcgtagtttc cgacatagag tttgattttt ccaaagtcaa
    25681 ggtcggccat gtgagtacaa actttgttta agaagtgacg gtcgtgggat actacgataa
    25741 ctgtgttatc aaagtcaatc aagaagtctt ctaaccaagt aatcgattgg atatccaaac
    25801 cgttagtagg ctcgtccaag agaagaacat ctggtttacc aaaaagtgct ttggcgagga
    25861 gaacctttac tttttcaccg ttggccaatt cgctcatgtt ttggtagtgt aattcttctg
    25921 gaatgtttag gttttgaagt agttgagagg cttcactctc tgcttcccaa cctccaagtt
    25981 cggcaaactc tccttcgagt tcggcagcac gaaccccgtc ctcgtctgag aaatcttcct
    26041 tcatgtagat agcatctttc tctttcatga tgctataaag tttttcattt cccatgataa
    26101 cgacatcaat ggcacgttca tcttcgtagt caaagtgatt ttgacgaaga acagagagac
    26161 gttcatctgg accaagagag atgtgaccag tagtaggttc gatatctcca gctaaaattt
    26221 ttaaaaaggt tgattttccg gcaccattag caccgattaa tccgtaagta tttccttctg
    26281 taaatttgat attgacatca tcaaaaagtt tgcgatcact aaaacgtagt gaaacatcag
    26341 atactgtaag caatattttt ctcctatatg tgtaatatat ttattctact agaaaataca
    26401 gaaatattca aatttttatt tgtcaatttt gtgtaaatta tatttacagt atcctttaca
    26461 caaatctgta aaaagcaagg ctgatttatt ttgataaatt acggttattt cattaaaaaa
    26521 atgctataat tgaaaggact atatcgaagg agaacaaaat gactaaaccc attattttaa
    26581 caggagaccg tccaacagga aaattgcata ttggacatta tgttggaagt ctcaaaaatc
    26641 gagtattatt acaggaagag gataagtatg atatgtttgt gttcttggct gaccaacaag
    26701 ccttgacaga tcatgccaaa gatcctcaaa ccattgtaga gtctatcgga aatgtggctt
    26761 tggattatct tgcagttgga ttggatccaa ataagtcaac tatttttatt caaagccaga
    26821 ttccagagtt ggctgagttg tctatgtatt atatgaatct agtttcgtta gcacgtttgg
    26881 agcgaaatcc aacagtcaag acagagattt ctcagaaagg atttggagaa agcattccga
    26941 caggattctt ggtctatcca atcgctcaag cagctgatat cacagctttc aaggctaatt
    27001 atgttcctgt tgggacagat cagaaaccaa tgattgagca aactcgtgaa attgttcgtt
    27061 cttttaacaa tgcatataac tgtgatgtct tggtagagcc ggaaggtatt tatccagaaa
    27121 atgagagagc agggcgtttg cctggtttag atggaaatgc taaaatgtct aaatcactaa
    27181 ataatggtat ttatttagct gatgatgcgg atactttgcg taaaaaagta atgagtatgt
    27241 atacagatcc agatcatatc cgcgttgagg atccaggtaa gattgaggga aatatggttt
    27301 tccattatct agatgttttt ggtcgtccag aagatgctca agaaattgct gatatgaaag
    27361 aacgttatca acgaggtggt cttggtgatg tgaagaccaa gcgttatcta cttgaaatat
    27421 tagaacgtga actgggtcct attcgtgagc gccgtattga atttgctaag gatatgggag
    27481 aagtttataa tatgattcaa aaaggtagtg aaagagcgcg tgaagttgcg ggtcaaaccc
    27541 tatctgaggt aaaaggggca atgggacttc attactttaa ctaagtttat tttacaagaa
    27601 actatcattt ctatctcgaa gaaaagatag ttttttattt acccctgtaa catttgacaa
    27661 atttttatag aatggtatga tagatacaat ataaaaagag tcaagctcaa aaagaaagaa
    27721 aagaggaaac ttcgaatgtc taattgggac actaaatttt tgaaaaaagg ttttaccttt
    27781 gatgatgtat tgcttattcc agctgaaagt catgtgttgc ctaacgatgc agatttaaca
    27841 actaaattgg cagataattt gactttaaat atcccaatta ttaccgctgc catggacaca
    27901 gttacagaga gtcaaatggc cattgctatt gctcgtgcag gtggtctcgg agttatccat
    27961 aaaaacatgt caattgctca acaagcagac gaggttcgta aggtaaaacg ttctgaaaat
    28021 ggagttatta ttgatccgtt cttcttgacg cctgaacata caattgctga agcagatgag
    28081 cttatgggtc gttaccgcat cagtggtgtt ccagttgttg aaacacttga aaatcgtaaa
    28141 ttggttggta ttttgacaaa ccgagatctt cgttttattt cagattataa tcaaccaatt
    28201 tcaaaccata tgactagtga aaatcttgtt actgctcctg tgggtacgga tcttgcaacg
    28261 gctgagagta ttcttcaaga gcatcgtatt gaaaaacttc cgttggtcga tgaagaaggc
    28321 agtctttctg gtttgatcac tatcaaagat attgaaaaag ttattgagtt tccaaatgcg
    28381 gctaaagatg aatttggtcg tcttctagtt gcaggtgcag taggtgttac ttcagataca
    28441 tttgaacgtg cagaggctct ttttgaggca ggagcggatg cgattgttat tgatactgca
    28501 catggtcatt ctgcaggtgt cttgcgtaaa attgccgaga ttcgtgctca tttcccagat
    28561 cggactttga ttgctggaaa tattgctact gctgaaggtg cacgtgccct ttatgaagcg
    28621 ggtgtagacg ttgttaaggt tggtattgga ccaggttcta tctgtactac tcgtgtgatt
    28681 gctggtgttg gtgttccgca agtaacagct atctacgatg ctgcagctgt tgcgcgcgaa
    28741 tatggtaaaa cgattattgc tgacggtggg atcaagtatt ctggagatat tgtaaaagca
    28801 cttgctgcag gtggaaatgc tgttatgctt ggatctatgt ttgctggaac tgatgaagct
    28861 ccaggcgaaa ctgaaatctt ccaaggacgt aaattcaaga cttaccgtgg tatgggatca
    28921 attgctgcta tgaagaaagg ttcaagcgac cgttatttcc aaggttctgt caatgaagca
    28981 aacaagctcg ttccagaagg aattgaaggt cgtgttgctt ataaaggagc ggcagctgat
    29041 attgttttcc aaatgattgg tggtattcgc tctggtatgg gttactgtgg tgcagctaac
    29101 cttaaagaac tacacgataa tgctcaattt attgaaatgt ctggtgctgg tttgaaagaa
    29161 agccatcctc atgatgtgca aattactaat gaggcaccaa attattctat gtaaaaaaca
    29221 atgaaaagaa ctccagtgaa aacaggagtt cttttacaat gttgtcaatt tccatttaca
    29281 gaagctttac catcctgaat agtgaagata cttagatttt ctggcagatt ttgaagatgg
    29341 tctaagcttg ttgttgtgat aaaggtttgg attgattgag aaatcgtttc taataatttt
    29401 aactgtctag tgttgtcaag ttcactcatc acatcgtcaa gcagtaatat aggagattct
    29461 gtggtaatgc tttccattaa ttcgatttct gctaatttta tcgagaggac gagactacga
    29521 tgttgacctt ggcttccgaa actagcatcc atcccattta tataaaaaga aatgtcatct
    29581 cgatgaggac cgacaccagt attcttttta aataaatctc tggatctact tttttctaaa
    29641 gcaattttga aagattcgga taagttttgt ttgtcagtta tattgacaga agattgatag
    29701 gatattgaca actcttcgat ctgattagag agttcaaaat gtttcttacg cccaaatgat
    29761 tctagttttt ttatgaaatc taagcggtga ttcattacac gacatccata atcaactagc
    29821 tgatcatcta acacagaaag gaatgtttca tctatttttt gagctgattt taggtaagtg
    29881 tttctttgct ttaggatgtg gttataattg gttaagtcag ataaatagat tggcttaatt
    29941 tgcccaagtt ccatatcaat gaattttcgt cgaatcgaag gtgctccttt aattagttgt
    30001 aaatcttcag gagcaaataa gacaacattc atgtgtccta cataatctga aaggcgtgcc
    30061 tgttttaagt gattaacttt tgttacacgg cctttttgtg ttagttcgat ttctagggga
    30121 atggatccag tttttttctg aacgagacct gaaagatgaa gttgttcctc atcaaaatga
    30181 atgagatttt tatctgttcg agttcgatga ctacgcgtta aggctaaaaa atagatagcc
    30241 tctaacatgt ttgtttttcc ttgtgcatta cgtcccaaaa agacattcaa tttaggatta
    30301 aagtctattt tcgtttcttt gtaattacga aaagtcttga gagatagatg ttgtagccac
    30361 atgattatct accagggaat cgtggagctt gttggctttt aggtgatgaa gcaggtttcg
    30421 atttgtcttt tttaactccc ttattcatct ttttgacaag tttagcgatc cgttcttttt
    30481 caactttatc agcttggtat tcatcttgtt cttcagaagt aggttgtgtc aacaagatgt
    30541 caatgttcat gtcagggatg tcaactttat cgccaatacg aagttttttt ccacgacgac
    30601 tctctaattc cctattaaag taaacagaat gttcagagag aaatgattta atagctcctc
    30661 cgctatgtgt aattccaagt tctttgagta gtgcttggag ggtaataaat tcttcaaata
    30721 atttgtattc cataattcac ctcaatcttt ggtattatac catattttcc taaaaatagt
    30781 gagagagaca gcgagaaatg taagcgattt ttatttcaaa agtgttacag ggaacaagaa
    30841 aatttcaggt tttcgtgata taatagaagt ctgtatataa ggaggtaaat catggagtta
    30901 gtgcatggaa tttcaacaca ttttatccaa tcaaaaaagt ttaaaacaaa caaaattacc
    30961 gtgcgtttta ccgctccatt atcccttgat acgattgcag gtcacatgtt gagtgcaagt
    31021 atgctagaga ctgctaatca gatgtacccc acttctcaag atttgaggag acacttggcc
    31081 agtctatacg gtacagatat gtcaaccaat tgtttcagaa gagggcaaag ccacattata
    31141 gaattgacat ttacctatgt tcgtgatgag tttttaagta ggaaaaacgt gctaacctct
    31201 cagattttgg aacttgtaaa agaaactctt ttttcacccg cagtagttga taatgggttt
    31261 gatccggcct tatttgaaat tgagaaaaaa caattgctag caagtttagc agctgatatg
    31321 gatgattctt tttattttgc acataaagaa ttggataaat tgttttttca tgatgaacgt
    31381 cttcaattgg aatatagtga tttacgaaat cgtattttag ctgaaactcc acaaagttct
    31441 tattcttgtt tccaagaatt tttagccaat gatcgaatag atttcttttt cctaggtgat
    31501 tttaatgagg ttgaaattca aaatgtatta gaatcatttg gctttaaagg tcgaaaagga
    31561 gatgtgaagg ttcagtattg tcaaccttat tctaatatcc ttcaggaagg tatggttcgg
    31621 aaaaatgtgg gacaatccat tttggaatta ggttatcatt accgttctaa atatggtgat
    31681 gagcaacatt tacccatgat tgtaatgaat ggtttacttg gtggatttgc tcactctaag
    31741 ctctttacaa atgtccgtga aaatgctgga ttagcttata ccatttcaag tgagcttgat
    31801 ttatttagtg gattcttgag gatgtatgct ggtatcaatc gagaaaatcg taaccaggct
    31861 cgtaaaatga tgaataatca actgcttgat ttaaaaaaag gttattttac agagtttgag
    31921 ttaaatcaga ccaaggaaat gattcgttgg tcgttgttac tttctcaaga taatcaatct
    31981 tcattgattg aacgtgctta tcaaaatgcc ttatttggaa aatcttcagc agactttaaa
    32041 agttggattg cagagcttga acaaattgac aaagatgcta tttgtagagt agctaataat
    32101 gtgaaactac aagcgattta ctttatggaa ggaatagaat gacaaaggtt gtttttgaag
    32161 aaaaatacta tccagctgta aaagaaaagg tttatcgaac tcgtttggcc aacggattga
    32221 cagttgctct tttgcctaaa aaggaattta aagaggttta cgggagtgtc actgtacagt
    32281 ttggttcggt agatacgttt gtcacagaag ttgacggata tgtaaaacaa tatcctggag
    32341 gaattgctca ttttcttgaa cataaattat ttgagagaga agattctagt gatttgatgt
    32401 cggcttttac gagtctaggt gcagatagta atgcctttac aagctttaca aaaacaaact
    32461 atcttttttc agcaacggat tattttttag aaaatttaga tttacttgat gaattggtaa
    32521 catcagcaca ctttactgaa gcttccattc tgacagagca ggatattatt cagcaagaac
    32581 gagaaatgta ccaagatgat ccagattcgt gtttattctt ttcaacttta gcgaatttgt
    32641 atcctggtac acctttagca actgatatag ttggaagtga ggagtccatt tcccaaatca
    32701 atctaactaa tttgcaagaa aattttacaa agttttacaa acctgtaaac atgtctctgt
    32761 ttttagttgg taattttgat gtggagcgag tacaggacta ttttgaaagc aaagaactga
    32821 aagattcaga ttttcaggaa gtagcaagag aaaagttgtt tttacagcct gtaaagccaa
    32881 cagatagtat gagaatggaa gtatcttctc ccaaactagc gattggagtt agaggtaagc
    32941 gagaagtttc tgaagcggat tgctatcgac atcatatttt attaaaatta ttgtttgcaa
    33001 tgatgtttgg ttggacttcg gatcgttttc aaaaatgtta tgaatcaggt aaaattgatg
    33061 cgtccttatc tctggaagtt gaaataacaa gtcgctttca ttttgtcatg ttgacaatag
    33121 atacgaaaga gccagttgct ttgtctcatc aatttaggaa ggctattcgt aattttacaa
    33181 aggatttaga tattacagag gaacatttag atattatcaa aagagagatg tttggcgaat
    33241 ttttcagtag catgaactct cttgaattta ttgcaacgca atatgatgct tttgaaaatg
    33301 gtgagacaat ttttgatttg ccgaaaattt tacaggaaat tactttagag gatgtccttg
    33361 atgctggaca tcatttaata gatgatggtg acatagttga ttttacaata ttcccatcgt
    33421 agtaacctat cataatagac actagaaaga agggatgaca agtatgagaa aaaaaacaat
    33481 tggagaggtt ttacgattag ctagaatcaa tcagggattg agtttagatg aattgcagaa
    33541 aaagacagaa atccagttag atatgttgga agcaatggaa gcagacgatt tcgatcaact
    33601 tccaagtcct ttttacacgc gttctttctt gaaaaaatat gcatgggctg ttgagttaga
    33661 tgaccaaatt gttttggatg cttatgattc tgggagtatg attacttatg aggaagtaga
    33721 tgttgatgaa gatgagttga caggtcgtag acgttcaagt aagaaaaaga agaaaaaaac
    33781 atcattttta cctttatttt attttatcct ttttgcttta tcgattttaa tttttgtgac
    33841 ttattatgtt tggaactata ttcaaactca accagaggag ccttctcttt ctaattacag
    33901 tgtggttcaa tcaacaagtt caactagctc tgttccccac tcctcaagta gtagttcttc
    33961 tagtatagaa tcagctataa gtgtatcagg cgaaggaaat catgtagaaa tcgcttataa
    34021 gacaagtaag gaaacagtta aattgcaatt ggcagtttca gatgttacaa gttgggtcag
    34081 tgtttcagaa agcgaacttg agggcggtgt aaccttatcg ccaaagaaga aaagtgcaga
    34141 agcaacagtt gcaactaaaa gtcctgtaac aattacgtta ggtgttgtaa aaggtgttga
    34201 tttgacagta gataatcaga ctgttgattt atcgaaatta acagctcaga ctggacaaat
    34261 cactgtaacc tttactaaaa attaaggaaa aacgaatgaa aaaagaacaa attcccaatc
    34321 tcttaacaat aggtcgaatt ctctttatac ctatttttat ctttatttta acgataggaa
    34381 attcgataga gagtcatata gttgcagcta ttatctttgc tgttgccagt attaccgact
    34441 atttagatgg atatttagct cgtaaatgga atgtggtcag taattttggt aaatttgcag
    34501 atcctatggc ggataagtta ctagttatgt cggcttttat tatgttgatt gagttaggta
    34561 tggctccggc ttggattgtt gcagtgatta tctgtcgtga gttagctgtg acaggtttaa
    34621 ggcttttatt ggttgaaact ggtggaacaa ttttagcagc agcaatgcct ggaaaaatta
    34681 aaacttttag tcagatgttt gctattattt tcttgctatt acattggact ttgcttggtc
    34741 aagttctact ttatgtagcc ttatttttca ctatctactc tggctatgac tatttcaagg
    34801 gtagtgccta tgtatttaaa gggacatttg gttcgaaatg aaatcaataa ttgatgtaaa
    34861 aaatctttct tttcgctata aagaaaatca gaactactac gatgtgaagg atattacgtt
    34921 tcacgtgaaa cgtggagaat ggctttcgat tgtagggcat aatggtagtg gtaaatcaac
    34981 gacggttcga ttaattgatg gcttactgga agcagaatcc ggagagattg taattgatgg
    35041 ccaacgtttg actgaggaaa atgtttggaa tatacgtcgt caaatcggta tggtttttca
    35101 aaatccagac aatcaatttg ttggagcgac tgttgaagat gatgttgctt ttggtttgga
    35161 aaatcaggga ctttctcgtc aagaaatgaa aaagagagtg gaagaagctc tggctttagt
    35221 tggcatgttg gactttaaaa agagagagcc agcgcgtcta tcaggtggcc aaaagcaacg
    35281 tgtggccatt gcaggtgttg tagccctaag accagctatt ttaatcttag atgaagcaac
    35341 gagtatgttg gatcctgagg ggcgtagaga acttattggg acagtaaaag gaattcgaaa
    35401 agactatgat atgacggtca tttctattac ccatgatttg gaagaagtcg ccatgagtga
    35461 tcgcgtattg gtcatgaaaa aaggggaaat tgaatcaact agtagtccaa gggagctttt
    35521 ctctcgaaat gatttagatc aaattggatt agacgatcct tttgctaatc aattaaaaaa
    35581 atctttgagc cagaatggct atgatttacc tgaaaattat ttgacagaaa gtgagctaga
    35641 ggataagcta tgggaattgc tctagaaaat gtgaatttta tatatcaaga aggtactccc
    35701 ttagcttcag cagctttgtc ggatgtttct ttgacgattg aagatggctc ttatacagct
    35761 ttaattgggc acacaggtag tggtaaatca actattttac aactcttaaa tggtttattg
    35821 gtgccaagtc aagggagtgt gagggttttt gataccttaa tcacctcgac ttctaaaaat
    35881 aaagatattc gtcaaattag aaaacaggtt ggcttggtat ttcagtttgc tgaaaatcag
    35941 atttttgaag aaacggtttt gaaggacgtt gcttttggac cgcaaaattt tggagtttct
    36001 gaagaagatg ctgtgaagac tgcgcgtgag aaactggctc tggttggaat tgatgaatca
    36061 ctttttgatc gtagtccgtt tgagctgtca gggggacaaa tgagacgtgt tgccattgca
    36121 ggcatacttg ccatggagcc atctatatta gtcttagatg agccaacagc tggtctagat
    36181 cctctaggga gaaaagagtt gatgaccctg ttcaaaaaac tccaccagtc agggatgacc
    36241 atcgtcttgg taacgcattt gatggatgat gttgctgaat atgctaatca agtctatgta
    36301 atggaaaagg gacgtttagt aaaggggggc aaaccaagtg atgtctttca agacgttgtt
    36361 tttatggaag aagttcagtt gggagtacct aaaattacgg ccttttgtaa acgattggct
    36421 gatagaggcg tgtcatttaa acgattaccg attaagatag aggagttcaa ggagtcgcta
    36481 aatggatagt atgattttgg ggcgttatat cccaggggat tcgattgttc accgattgga
    36541 tccacgtagc aaattgcttg ctatgatgct actgattttg attgtgtttt gggctaataa
    36601 ccccttgacg aatctgattc tttttatagc gacagggata tttattgcct tgtcaggagt
    36661 atctctttca ttttttattc agggcttgaa gtctatgttt ttcttgattg ccttcacaac
    36721 tatttttcaa ctatttttca tttctaatgg gaatgtttta tttgagtttt cgtttgtgag
    36781 aatcacggat tatgctttgc aacaagctgg gattattttt tgtcgctttg tattgattat
    36841 tttcttttca actttgttaa ccttaacaac catgccttta agtttggcat cagctgtcga
    36901 agctttatta gcacctttaa agcgtgtgaa agttccagtt catgaaattg gattgatgct
    36961 gtctatgagt ttgcgttttg tcccaacctt gatggatgat acgactcgga ttatgaatgc
    37021 acagaaagct cgtggagtgg attttggaga aggaagcatc gttcaaaaag taaaggcgat
    37081 gattcccatt ttgattcctc tttttgcgac aagtttaaaa cgtgcagatt ccttggctat
    37141 cgctatggaa gcgcgtggct atcagggtgg aaaaggcaga agtcaatacc gacaattgaa
    37201 atggactcta aaggatacgc tgaccattct tgttattctc gtacttggtt gttgtttatt
    37261 tttcttaaaa tcttagtagc tttcaggaat tgataaaaag ttactgtaac agtttttgat
    37321 ataaaggtag ggatatgaac cgttttaaaa aatcaaaata tgtcattatt gtttttgtca
    37381 ctgttctgct tgtgtcagct ctcttagcga cgacttattc aagtacaatt gtgacaaaat
    37441 taggagatgg aatctcattg gttgatagag ttgtacaaaa accttttcag tggtttgatt
    37501 ctgtcaaatc agatttggct catttgacac gaacatataa tgaaaatgaa agtttgaaga
    37561 aacagcttta ccaattagaa gttaaatcaa atgaggtgga aagtttaaag acagaaaatg
    37621 aacaactgcg ccaattgctt gatatgaagt ctaaattgca agccacaaag actttagcag
    37681 cagatgttat tatgcgttct ccggtatctt ggaagcagga gttgacctta gatgcaggta
    37741 gatcaaaagg tgcttctgag aacatgttag ctattgcaaa tggtggcttg attgggagtg
    37801 tttcaaaagt agaggagaac tctactatag tcaaccttct gacaaatacg gaaaatgctg
    37861 ataagatttc tgttaaaatt caacatggct ctactacaat ttatggaatt attattggct
    37921 atgacaagga aaatgacgtt cttaaaatta gccaattaaa tagtaatagc gatattagtg
    37981 cgggagataa ggtgactact ggtggattag gaaactttaa cgttgctgat attcctgttg
    38041 gtgaagtggt tgccacaacg catagtacag actatttgac acgagaagta actgttaaat
    38101 tgagtgcaga tactcataat gtagatgtga tagaattagt ggggaattca taatgagaca
    38161 gttgaagcga gttggagtat ttttattgct tcctttcttt gttctaattg acgcccatat
    38221 tagccagctt ctgggctcat ttttccccca tgtacatttg gctagtcatt ttctttttct
    38281 atttctctta tttgagacga tagaagtatc agagtatctc tacctagtct attgttttgt
    38341 tataggcttg gtttatgatg tttacttttt ccatctaata gggattacaa ctctcttatt
    38401 tatcttattg ggagccttcc ttcataaatt gaatagtgtt attttgttga atcgttggac
    38461 aagaatgcta gctatgattg tgctgacatt cctgtttgaa atgggtagtt atcttttggc
    38521 ttttatggta gggttgacag tagatagcat gtcgattttt atagtctata gcttggtacc
    38581 gacgatgatt ttaaattttt tatggattac tgtttttcaa tttatttttg aaaaatatta
    38641 tctataagaa cgacatataa atgtaacaaa ggcgtaatat ttattaggcc tttttttggt
    38701 atactagtat tgtctttaaa agaaggagta tctacgtaat atgaagaaaa aaatcttagc
    38761 gtcactttta ttaagtacag taatggtttc tcaagtagct gttttaacaa ctgcgcatgc
    38821 agaaacgact gatgacaaaa ttgctgctca agataataaa attagtaact taacagcaca
    38881 acaacaagaa gcccaaaaac aagttgacca aattcaggag caagtatcag ctattcaagc
    38941 tgagcagtct aacttgcaag ctgaaaatga tagattacaa gcagaatcta agaaactcga
    39001 gggtgagatt acagaacttt ctaaaaacat tgtttctcgt aaccaatcgt tggaaaaaca
    39061 agctcgtagt gctcaaacaa atggagccgt aactagctat atcaatacca ttgtaaactc
    39121 aaaatcaatt acagaagcta tttcacgtgt tgctgcaatg agtgaaatcg tatctgcaaa
    39181 caacaaaatg ttagaacaac aaaaggcaga taaaaaagct atttctgaaa aacaagtagc
    39241 aaataatgat gctatcaata ctgtaattgc taatcaacaa aaattggctg atgatgctca
    39301 agcattgact acgaaacagg cagaactaaa agctgctgaa ttaagtcttg ctgctgagaa
    39361 agcgacagct gaaggggaaa aagcaagtct attagagcaa aaagcagcag ctgaggcaga
    39421 ggctcgtgca gctgcggtag cagaagcagc ttataaagaa aaacgagcta gccaacaaca
    39481 atcagtactt gcttcagcaa acactaactt aacagctcaa gtgcaagcag tatctgaatc
    39541 tgcagcagca cctgtccgtg caaaagttcg tccaacatac agtacaaacg cttcaagtta
    39601 tccaattgga gaatgtacat ggggagtaaa aacattggca ccttgggctg gagactactg
    39661 gggtaatgga gcacagtggg ctacaagtgc agcagcagca ggtttccgta caggttcaac
    39721 acctcaagtt ggagcaattg catgttggaa tgatggtgga tatggtcacg tagcggttgt
    39781 tacagctgtt gaatcaacaa cacgtatcca agtatcagaa tcaaattatg caggtaatcg
    39841 tacaattgga aatcaccgtg gatggttcaa tccaacaaca acttctgaag gttttgttac
    39901 atatatttat gcagattaat ttacagaggg actcgaatag agccctcttt tcaggtttta
    39961 ccgtgacaat ccctattaaa aattatatca aaatagcttg aaaatattgg aaaagtatgg
    40021 tagaatgaaa attgtcgtgt gaacgataat actcattctt gatgaattgt gaagcagttg
    40081 cccttgggtc gttttgcgag ttgaagtcaa gaagaggaaa aaaacaaaaa ggagaaatac
    40141 tcatggcagt aatttcaatg aaacaacttc ttgaggctgg tgtacacttt ggtcaccaaa
    40201 ctcgtcgctg gaatcctaag atggctaagt acatctttac tgaacgtaac ggaatccacg
    40261 ttatcgactt gcaacaaact gtaaaatacg ctgaccaagc atacgacttc atgcgtgatg
    40321 cagcagctaa cgatgcagtt gtattgttcg ttggtactaa gaaacaagca gctgatgcag
    40381 ttgctgaaga agcagtacgt tcaggtcaat acttcatcaa ccaccgttgg ttgggtggaa
    40441 ctcttacaaa ctggggaaca atccaaaaac gtatcgctcg tttgaaagaa attaaacgta
    40501 tggaagaaga tggaactttc gaagttcttc ctaagaaaga agttgcactt cttaacaaac
    40561 aacgtgcgcg tcttgaaaaa ttcttgggcg gtatcgaaga tatgcctcgt atcccagatg
    40621 tgatgtacgt agttgaccca cataaagagc aaatcgctgt taaagaagct aaaaaattgg
    40681 gaatcccagt tgtagcgatg gttgacacca atactgatcc agatgatatc gatgtaatca
    40741 tcccagctaa cgatgacgct atccgtgctg ttaaattgat cacagctaaa ttggctgacg
    40801 ctattatcga aggacgtcaa ggtgaggatg cagtagcagt tgaagcagaa tttgcagctt
    40861 cagaaactca agcagattca attgaagaaa tcgttgaagt tgtagaaggt gacaacgctt
    40921 aatttataca aatagtaatt acctaggagg gcggggctta gcccggctct cctattttca
    40981 aaaaatatag gagaattaaa atggcagaaa ttacagctaa acttgtaaaa gagttgcgtg
    41041 aaaaatctgg tgccggtgtt atggacgcta aaaaagcgct tgtagaaaca gacggtgaca
    41101 tcgaaaaagc gattgaattg cttcgtgaaa aaggtatggc taaggcagct aagaaagctg
    41161 accgtgttgc tgcagaaggt ttgactggtg tttatgttaa cggtaatgtt gcagcagtta
    41221 ttgaagtaaa cgctgaaact gacttcgttg caaaaaacgc tcaattcgtt gaattggtaa
    41281 atactacagc taaagtcatt gctgaaggaa aacctgctaa taatgaagaa gctcttgctt
    41341 tgataatgcc ttcaggtgaa actcttgaag ctgcatacgt atctgcaaca gcaactatcg
    41401 gagagaaaat ctcattccgt cgctttgcat tgattgaaaa aacagacgca caacactttg
    41461 gagcatacca acataacggt ggacgtatcg gtgttatttc agttgttgaa ggtggagacg
    41521 aagcacttgc taaacaattg tcaatgcaca tcgcagcgat gaaaccaaca gttctttctt
    41581 acaaagaatt ggatgagcaa ttcgttaaag atgagttggc acaattgaat cacgttatcg
    41641 accaagacaa cgaaagccgt gcaatggtta ataaaccagc tcttccacac ttgaagtatg
    41701 gatcaaaagc tcaattaact gatgatgtta ttgctcaagc tgaagctgac atcaaagctg
    41761 aattggctgc agaaggcaaa ccagaaaaaa tctgggacaa aattatccca ggtaaaatgg
    41821 atcgcttcat gcttgataat actaaagttg accaagctta cacacttctt gcacaagttt
    41881 acatcatgga tgacagcaag acagttgaag cataccttga atcagttaac gcttcggtag
    41941 ttgagtttgc tcgctttgaa gttggtgaag gtatcgagaa agctgcaaac gacttcgaag
    42001 ctgaagttgc agctacaatg gcagcagcct tgaataacta ataatagaaa ggaagcaatt
    42061 tgcttccttt tttgtatagg gcttatattt ttcctgaaat tgtttttccc ccagtctcac
    42121 tcgattagaa taattaaaac aaaaagccct ataataaggg ctaagtgcat ttaggagact
    42181 atacttcaaa ttcatagtaa gcgcgtcata acaaggtatc tatcctaatt ccccaacttc
    42241 cagtatacta gataaaaaat aattatcgga ggaaaggtat tgtacgatga tgattcaact
    42301 aagtgattta ggtcaagttc acattgtttg tggcaagaca gatatgaggc agggaataga
    42361 ctcattagcc tatgtagtta aaacccactt tgaattggat tctttctccg gtcaagtctt
    42421 tctcttttgt ggtggacgta aagaccgctt taaagtcctt tactgggatg gtcaaggatt
    42481 ttggctacta tataaacgct ttgagaacgg aaaactgact tggctaagta cagaaaagga
    42541 tgtcaaagct ctcgcacctg aacaagtaga ctagcttatg aagggctttt ctatcactcc
    42601 aaaaatatag tagattgaaa ctagaatagt acacctctgc ttctaaaaca ttgttagaaa
    42661 tcgatttgac tgtcctgatc gatttgtcct gttcttattt cattttacta taaatccatc
    42721 agaaagtcgt gatttctatt gaaatgagga ctttcttttt acactcatct gctttcaaaa
    42781 agcattctag tccgtctccg attaacgatg gactttatca cctccttctc tagtccttgt
    42841 atgacatctt ccaaagttcg aaaggcttta ttct
//
LOCUS       DAVBOG010000013        40624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.013, whole genome shotgun sequence.
ACCESSION   DAVBOG010000013 DAVBOG010000000
VERSION     DAVBOG010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.013"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..233)
                     /locus_tag="VQ865_000750"
     CDS             complement(<1..233)
                     /locus_tag="VQ865_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135135.1"
                     /translation="MIGKNIKSLRKTHDLTQPEFARIIGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTL"
     gene            complement(676..1131)
                     /locus_tag="VQ865_000751"
     CDS             complement(676..1131)
                     /locus_tag="VQ865_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135136.1"
                     /translation="MGAARDFLELINHKGLPLFNPLVGDSHVNNRQEYDNTGSGNLQP
                     EKWNETAKQLYNAIMWLIILWNAKPDTPLFNFKDEVIKYKTYEPFESSIKRVNTTIKN
                     GSKGKTLTEMINGYRADNDIRDEICNFNILKNKIRDMKDQQGNTMESYF"
     gene            complement(1406..3143)
                     /locus_tag="VQ865_000752"
                     /pseudo
     CDS             complement(1406..3143)
                     /locus_tag="VQ865_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511339.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
     gene            complement(3306..4190)
                     /locus_tag="VQ865_000753"
     CDS             complement(3306..4190)
                     /locus_tag="VQ865_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HET3135137.1"
                     /translation="MKKAMVIINPTSGGEKALDYKEKLENKAKEYFEYVETKITEKAL
                     DATHFAEEASREQYDAVVVFGGDGTVNEVISGIDERDYIPKLGIIPGGTGNLITKLLE
                     INQDIDGAIDELDFDLINKIDIGKANDNYFGYIFSIGSLPEAIHNVEIEDKTKFGILT
                     YAVNTMKSVMTDQVFNIKVETENGNYVGEASHVLVLLTNYFADKKIFEENKDGYANIL
                     ILKDASIFSKLSVIPDLLKGDVVANDNIEYIKARNIKISSDSELESDVDGDKSDNLPV
                     EIKVLAQRVEVFSKPKED"
     gene            complement(4302..5156)
                     /locus_tag="VQ865_000754"
     CDS             complement(4302..5156)
                     /locus_tag="VQ865_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HET3135138.1"
                     /translation="MLGAIIGDIVGSVYEWNNIKTKDFPLFRKDCFFTDDTVMTCAVA
                     EAIMNGGQKDDFIDAMKKYGRMYPNADYGARFNAWLNSDNREPYNSFGNGSAMRISPC
                     AWIMDCGFYAKTGMWPSSRGLTSLSAEVTHNHPEGVKGAMATADAIFLCRFYFGGYCR
                     EYEQSINDNPTECKRRIKDYIEKEYDYNLSQTLDEIRPNYRFNETCQETVPQAIIAFL
                     ESRDFEDAIRNAISLGGDSDTLAAITCSIAEAAYGIPDWIKDKAYSYLDEPLKDVVRR
                     WENRIKAY"
     gene            complement(5214..5972)
                     /locus_tag="VQ865_000755"
     CDS             complement(5214..5972)
                     /locus_tag="VQ865_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000262024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3135139.1"
                     /translation="MVVYIRQSKLPSEVSINKYNAQVGAYLQGEEVILYQSFSEIKEL
                     TSEDIVVDYIMETRALLKMMGLNVPVHDYPIELKEFYGRKIYAGILGEIVNIPDNWGK
                     FIKPKAGSKVFTGRVVNGTHDLIGIGLPFDYPIWISEVVEFIAEWRCFVLDGRVLDVR
                     PYTGDYHAQFDASVIDEAISCWKDAPIAYGLDIGVTRDGRTLVVEVNDGYALGNYGLS
                     PLKSINFHRARWKEMVKPYFEKNEIFKIQQDVIF"
     gene            complement(6034..6222)
                     /locus_tag="VQ865_000756"
     CDS             complement(6034..6222)
                     /locus_tag="VQ865_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HET3135140.1"
                     /translation="MATDKNRIMISLDDKNLEKLENLVEDARDRRGMRLTKSQVIELL
                     LNTVDYFDDIMGAIYSKK"
     gene            complement(6545..7111)
                     /locus_tag="VQ865_000757"
     CDS             complement(6545..7111)
                     /locus_tag="VQ865_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135141.1"
                     /translation="MVILELYQNDYSKDLVAFDSIEDGKAFVAQIPGYTLETEDGFEV
                     EYFNPKNIPDYMEIIFNGNIVPLSKFMFDPEENVNIIWKEISNLSLKNDRVIEGYSKI
                     DAYVVNNHEVKAYVETRETNYRKAKDFLESRGYEIDRSFFGSEDGEAILYRKKGIEVW
                     HFLCHLDPMFVEIEDVEGYVKEEVGEIQ"
     gene            complement(7379..9058)
                     /locus_tag="VQ865_000758"
                     /pseudo
     CDS             complement(7379..9058)
                     /locus_tag="VQ865_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031864.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
     gene            complement(9150..9311)
                     /locus_tag="VQ865_000759"
     CDS             complement(9150..9311)
                     /locus_tag="VQ865_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135142.1"
                     /translation="MDNDWNGLADLIANLIAKYAGALDLDNLPDPTPAKNQEMKNSFD
                     MAKTQIETD"
     gene            complement(9995..10309)
                     /locus_tag="VQ865_000760"
     CDS             complement(9995..10309)
                     /locus_tag="VQ865_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001835032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135143.1"
                     /translation="MGITWKDIEIDKEREGEIDKKSTPIFYGEFKNVRLSKEEYKNLK
                     EKLNSHTDIMINKLSRYMESSGKTYQNHYVTILKWYEEDKDKLRQKGLNKKMNYDVGE
                     SL"
     gene            complement(10275..10664)
                     /locus_tag="VQ865_000761"
     CDS             complement(10275..10664)
                     /locus_tag="VQ865_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000690676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3135144.1"
                     /translation="MPKRYLLDGKTPRISATNIDNGILGYYEDIDDKNYRVFENFISV
                     SFLGAVFYHKYKASLDMKIHCLKLKNKELNKEVAFYLTSIIRQALKNTEYKDQISSTV
                     LPDIKIKLPIDSRGTPDWNYMERYRDR"
     gene            complement(11052..11846)
                     /locus_tag="VQ865_000762"
     CDS             complement(11052..11846)
                     /locus_tag="VQ865_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000677523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135145.1"
                     /translation="MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKST
                     LIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIAILPQSPIIPESITVADLVSRGR
                     FPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
                     LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKL
                     VAEGKPEDILNDKLVKDIFNLEAKIIRDPISNSPLMIPIGKHHVSS"
     gene            complement(11846..12853)
                     /locus_tag="VQ865_000763"
     CDS             complement(11846..12853)
                     /locus_tag="VQ865_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3135146.1"
                     /translation="MQNLIIGIQKRKNRITLFSSLFLLIIISLSFFILLIGDESYSFS
                     TLIKVLNSETVPGASFSIMEIRLPKLLAGIIAGWSFGLAGFIFQTMLRNPLASPDIIG
                     VTSSSSIAAVFCILVLKTNSLTTGIISITCGLTSSLILFLLAKKDGFSAARLIILGIG
                     FQAVTRAGTSFLLLKVARYELQEVMRWLSGSLSFTKLDDIPLVLIVSIIATILVLFFN
                     KRLEIIELGEEIAIGLGANPELSRLVLIFCAVSLTAFSTSITGPIACISFLAGPIALN
                     IGKKRSPILAGLVGILLVLLSDIFSQNILPARYPVGVVTGLLGSPYLIYLLIKMNRRN
                     I"
     gene            complement(12853..13860)
                     /locus_tag="VQ865_000764"
     CDS             complement(12853..13860)
                     /locus_tag="VQ865_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3135147.1"
                     /translation="MRNKKQINLGIIFVICLGLLITIFLSLKLGTKEINIRDFLAAFG
                     MGNTNDDFIKSIIYKRIPRTIFAILAGSSLAISGVLMQSVTRNPIADPGILGINTGAS
                     LSVVIGLSFLGISSSISHISFAIIGGLVSAIFVYAIAVSGKAGLTPIKLALSGTCVSM
                     ALSSFVSFLILPNNNVLDKFRFWQIGSLGAATLSSISTLLPFIILGHLIAIFISSDLN
                     ALAMGDEMAVGLGVNVNRIRSLAIIASVLLCSSITAIGGPIGFVGLIVPHFCGLFISK
                     DIRTMTISSSFIGAELLLICDIIGRMLGKPGEIEVGIITAIIGGPVLIYVTMKNRGVN
                     N"
     gene            complement(13850..14875)
                     /locus_tag="VQ865_000765"
     CDS             complement(13850..14875)
                     /locus_tag="VQ865_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000790748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3135148.1"
                     /translation="MKNKFFLIAILAMCIVFSACSSNSVKNEENTSKEHAPDKIVLDH
                     AFGQTILDKKPERVATIAWGNHDVALALGIVPVGFSKANYGVSADKGVLPWTEEKIKE
                     LNGKANLFDDLDGLNFEAISNSKPDVILAGYSGITKEDYDTLSKIAPVAAYKSKPWQT
                     LWRDMIKIDSKALGMEKEGDELIKNTEARISKELEKHPEIKGKIKGKKVLFTMINAAD
                     TSKFWIYTSKDPRANYLTDLGLVFPESLKEFESEDSFAKEISAEEANKINDADVIITY
                     GDDKTLEALQKDPLLGKINAIKNGAVAVIPDNTPLAASCTPTPLSINYTIEEYLNLLG
                     NACKNAK"
     gene            complement(15268..15486)
                     /locus_tag="VQ865_000766"
     CDS             complement(15268..15486)
                     /locus_tag="VQ865_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001207345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135149.1"
                     /translation="MALNYKPLWIQLAKKGLKKTDVIAMAGLTTNVMAQMGKDKPITF
                     KNLERICKALSCTPNDIISFEDNFSDEE"
     gene            complement(15732..16010)
                     /locus_tag="VQ865_000767"
     CDS             complement(15732..16010)
                     /locus_tag="VQ865_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135150.1"
                     /translation="MKKDKEVYDKVCEYLSPHLNKDMEVLELACWFRVITVIEANSYV
                     NIRSSRLLPKFKTQKINSWYAAYNIHFNNGYCKQHTNEFKDSLKSLIL"
     gene            complement(16224..17855)
                     /gene="rlmD"
                     /locus_tag="VQ865_000768"
     CDS             complement(16224..17855)
                     /gene="rlmD"
                     /locus_tag="VQ865_000768"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000914584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HET3135151.1"
                     /translation="MLKKNDIVEVEIVDLTHEGAGVAKVDGLVFFVENALPSEKILMR
                     VLKVNKKIGFGKVEKYLVQSPHRNQDLDLAYLRSGIADLGHLSYPEQLKFKTKQVKDS
                     LYKIAGIADVEVAETLGMEHPVKYRNKAQVPVRRVNGVLETGFFRKNSHDLMPLEDFF
                     IQDPVIDQVVVALRGLLRRFDLKPYDEKEQSGLIRNLVVRRGHYSGQIMVVLVTTRPK
                     VFRVDQLIEQVIKQFPEIVSVMQNINDQNTNAIFGKEWRTLYGQDYITDQMLGNDFQI
                     AGPAFYQVNTEMAEKLYQTAIDFAELKKDDVVIDAYSGIGTIGLSVAKHVKEVYGVEL
                     IPEAVENSKKNAQLNNISNAHYVCDTAENAMKNWLKDGIQPTVILVDPPRKGLTESFI
                     KASAQTGADRIAYISCNVATMARDIKLYQELGYELKKVQPVDLFPQTHHVETVALLSK
                     LDVDKHISVEIELDEMDLTSAESKATYAQIKEYVWNKFELKVSTLYIAQIKKKCGIEL
                     REHYNKSKKDKQIIPQCTPEKEEAIMDALRHFKMI"
     gene            complement(17929..18903)
                     /locus_tag="VQ865_000769"
     CDS             complement(17929..18903)
                     /locus_tag="VQ865_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1002 domain-containing protein"
                     /protein_id="HET3135152.1"
                     /translation="MRKKLFLTSAAVLWAVTAMNSVHAATDVQKVIDETYVQPEYVLG
                     SSLSEDQKNQTLKKLGYNASTDTKELKTMTPDVYSKIMNVANDSSLQLYSSAKIQKLG
                     DKSPLEVKIETPENITKVTQDMYRNAAVTLGMEHAKITVAAPIPVTGESALAGIYYSL
                     EANGAKVPQANKDLAQEELKALSDINAENKDKSGYDANKLNVALADIKSGLAKAKESK
                     GNLTEEDIRKIVEDTLKNYKLDQVITGNQINIIINFALNLSKSDILSNADFTKTLNDL
                     KQSIVSQAGDSFKNINLNFDADKALEDGGNFLSSLWQALVNFFKSFGS"
     gene            complement(18977..19591)
                     /gene="pmp23"
                     /locus_tag="VQ865_000770"
     CDS             complement(18977..19591)
                     /gene="pmp23"
                     /locus_tag="VQ865_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000476388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall hydrolase Pmp23"
                     /protein_id="HET3135153.1"
                     /translation="MFKRIRRVLVLAVFLFAGYKAYRVHQDVKQVMTYQPMVREILSE
                     KDTPANEELVLAMIYTETKGKEGDVMQSSESASGSTNTINDNASSIRQGIQTLTGNLY
                     LAQKKGVDIWTAVQAYNFGPAYIDFIAQNGKENTLALAKQYSRETVAPLLGNTTGKTY
                     SYIHPISIFHGAELYVNGGNYYYSRQVRLNLYIIKCFTLFSTSG"
     gene            complement(19591..20565)
                     /locus_tag="VQ865_000771"
     CDS             complement(19591..20565)
                     /locus_tag="VQ865_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HET3135154.1"
                     /translation="MDIYIKKAIIHQFSPDDTELFLADKFLNITPKIEEYLRKKIEHV
                     YSDEAKTGIFEEENPFFNHITDDLLETSVTLANLWKEEFSISENLKTNDLIFVQFSKE
                     GVEHFAFLRIALRETLTHLGGEVDNPIKLTQNNLPGFGTGADEALVVNLQSRKYHLIE
                     KRIKYNGTFLNYFSDNLLAVAPKISPKKSIKELEKTAQRIAESFNTDDFQFQSKVKSA
                     IFNNLEESNELSPEKLANDLFDNNLTARLSFIDQVKEAVPEPVQFDEIDASRQLKKFE
                     NQKLSLSNGIELIVPNNVYQDAESVEFIQNENGTYSILIKNIEDIQSK"
     gene            complement(20573..21829)
                     /locus_tag="VQ865_000772"
     CDS             complement(20573..21829)
                     /locus_tag="VQ865_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HET3135155.1"
                     /translation="MIFDKDDFKAYDADLWNAIAKEEERQQNNIELIASENVVSKAVM
                     AAQGSILTNKYAEGYPGRRYYGGTDVVDVVETLAIERAKEIFGAKFANVQPHSGSQAN
                     CAAYMSLIEPGDTVMGMDLAAGGHLTHGAPVSFSGQTYNFLSYSVDPETELLDFDAIL
                     KQAQEVKPKLIVAGASAYSQIIDFSKFREIADAVGAKLMVDMAHIAGLVAAGLHPSPV
                     PYAHITTTTTHKTLRGPRGGLILTNDEDLAKKINSAIFPGIQGGPLEHVVAAKAVSFK
                     EVLDPAFKEYAANVIKNSKAMADVFLQDPDFRIISGGTENHLFLVDVTKVVENGKVAQ
                     NLLDEVNITLNKNSIPYETLSPFKTSGIRIGAAAITARGFGEEESRKVAELIIKTLKN
                     SENEAVLEEVRSAVKELTDAFPLYEE"
     gene            complement(21891..22322)
                     /locus_tag="VQ865_000773"
     CDS             complement(21891..22322)
                     /locus_tag="VQ865_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000942930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135156.1"
                     /translation="MLRDLQETDVKAICDINQEALGYTFSPEETASQLARLSQDSHHF
                     LLGYEDAANHVLLGYVHAEVYESLYSKAGFNILALAVSPQAQGQGIGKSLLQGLEQEA
                     KRCGYGFIRLNSANHRLGAHAFYEKVGYTCDKMQKRFIRIF"
     gene            complement(22324..22923)
                     /locus_tag="VQ865_000774"
     CDS             complement(22324..22923)
                     /locus_tag="VQ865_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HET3135157.1"
                     /translation="MDRIRQELENGGAVILPTETVYGLFAKALDEKAVDHVYQLKRRP
                     RDKALNLNVATLEDILHFSKNQPAYLQKLVETFLPGPLTIILEANDRVPYWVNSDLAT
                     IGFRMPSHPITLDLIRETGPLIGPSANISGQASGVTFEQILKDFDQEVLGLEDDAFLT
                     GQDSTIVDLSGDKVKILRQGAIKREDILARLPEISFEEA"
     gene            complement(22910..23749)
                     /gene="prmC"
                     /locus_tag="VQ865_000775"
     CDS             complement(22910..23749)
                     /gene="prmC"
                     /locus_tag="VQ865_000775"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000761890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HET3135158.1"
                     /translation="MKLAQLFSNFEEELIRQGEEAESLSFVYRSLKNLSFTDFIFALQ
                     QEVTTEEEKQFVEDIYQQLAAHKPAQYIIGQADFYGMHLKVDERVLIPRPETEELVEL
                     ILTENLETNLSVLDIGTGSGAIALALAKNRPDWSVTAADVSQEALELASENASDQNLN
                     IFFKKSDCFAEISEKYDIIVSNPPYISREDESEVGLNVLHSEPHLALFADEDGLAIYC
                     RIAEDAKDYLKDGGKIYLEIGYKQGQSVPELFRKHLPEKRVRTLKDQFGQDRMVVVDD
                     GQD"
     gene            complement(23749..24828)
                     /gene="prfA"
                     /locus_tag="VQ865_000776"
     CDS             complement(23749..24828)
                     /gene="prfA"
                     /locus_tag="VQ865_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002262255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HET3135159.1"
                     /translation="MNIYDQLQAVEDRYEELGELLSDPDVVSDTKRFMELSKEEASNR
                     DTVIAYREYKQVLQNIVDAEEMIKESGGDADLEEMAKQELKDAKAEKEEYEEKLKILL
                     LPKDPNDDKNIILEIRGAAGGDEAALFAGDLLTMYQKYAEAQGWRFEVMEASMNGVGG
                     FKEVVAMVSGQSVYSKLKYESGAHRVQRVPVTESQGRVHTSTATVLVMPEVEEVEYDI
                     DPKDLRVDIYHASGAGGQNVNKVATAVRIVHLPTNIKVEMQEERTQQKNREKAMKIIR
                     ARVADHFAQIAQDEQDAERKSTIGTGDRSERIRTYNFPQNRVTDHRIGLTLQKLDTIL
                     SGKLDEVVDALVLYDQTQKLEELNK"
     gene            complement(24838..25317)
                     /locus_tag="VQ865_000777"
     CDS             complement(24838..25317)
                     /locus_tag="VQ865_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135160.1"
                     /translation="MTIELRDVTMENYFDVLNLDVKEYQKQFIATNAISLAEAYVYTK
                     NGDFVATLAVYDNDAIIGFVMIAYDKKIGISSGNYLLFRFMIDRNFQNQGYFKPIMDK
                     VLDYVRTAPAGLSNKLWLSYEPENEQARFCYLSYGFKETGEIAENEVVAIYDLTIEK"
     gene            complement(25307..25906)
                     /locus_tag="VQ865_000778"
     CDS             complement(25307..25906)
                     /locus_tag="VQ865_000778"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HET3135161.1"
                     /translation="MAQLYYRYGTMNSGKTIEILKVAYNYEEQGKGVVIMTSALDTRD
                     GVGYVSSRIGMKRPALAIEETTDIFGYIRDLPEKPYCVLVDEAQFLKRHHVYDLARVV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLLADKIDEIKTICQYCKKKATMVLRTQDGL
                     PVYDGEQIQIGGNETYISVCRKHYFTPMITSNKEQNYDN"
     gene            26029..26211
                     /locus_tag="VQ865_000779"
     CDS             26029..26211
                     /locus_tag="VQ865_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005589823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HET3135162.1"
                     /translation="MPFVRIDLFEGRTLEQKKALAKEVTEAVVRNTGAPQSAVHVIIN
                     DMPEGTYFPQGEMRTK"
     gene            26348..27721
                     /gene="mnmE"
                     /locus_tag="VQ865_000780"
     CDS             26348..27721
                     /gene="mnmE"
                     /locus_tag="VQ865_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002906470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HET3135163.1"
                     /translation="MITREFDTIAAISTPLGEGAIGIVRLSGTDSFAIAQKIFKGKDL
                     NKVASHTLNYGHIIDPLTGKVMDEVMVGAMKSPKTFTREDIIEINTHGGIAVTNEILQ
                     LAIREGARLAEPGEFTKRAFLNGRVDLTQAEAVMDIIRAKTDKAMNIAVKQLDGSLSD
                     LINNTRQEILNTLAQVEVNIDYPEYDDVEEATTAVVREKTMEFEQLLTNLLRTARRGK
                     ILREGISTAIIGRPNVGKSSLLNNLLREDKAIVTDIAGTTRDVIEEYVNINGVPLKLI
                     DTAGIRETDDIVEQIGVERSKKALKEADLVLLVLNASEPLTAQDRQLLEISQDTNRII
                     LLNKTDLPETIETSKLPEDVIRISVLKNQNIDKIEERINNLFFENAGLVEQDATYLSN
                     ARHISLIEKAVESLQAVNQGLELGMPVDLLQVDLTRTWEILGEITGDAAPDELITQLF
                     SQFCLGK"
     gene            complement(27768..28703)
                     /gene="dapA"
                     /locus_tag="VQ865_000781"
     CDS             complement(27768..28703)
                     /gene="dapA"
                     /locus_tag="VQ865_000781"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HET3135164.1"
                     /translation="MSYQDLKECKIITAFITPFHEDGSINFDAIPALIEHLLAHHTDG
                     ILLAGTTAESPTLTHDEELELFAAVQKVVNGRVPLIAGVGTNDTRDSIEFVKEVAEFG
                     GFAAGLAIVPYYNKPSQEGMYQHFKTIADASDLPIIIYNIPGRVVVELTPETMLRLAD
                     HPNIIGVKECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGD
                     EMHEMFTAIAESDMKKAAAIQRKFIPKVNALFSYPSPAPVKAILNYMGFEAGPTRLPL
                     VPAPEEDAKRIIKVVVDGDYEATKATVTGVLRPDY"
     gene            complement(28759..29835)
                     /locus_tag="VQ865_000782"
     CDS             complement(28759..29835)
                     /locus_tag="VQ865_000782"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000542485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HET3135165.1"
                     /translation="MGYTVAVVGATGAVGAQMIKMLEESTLPIDKIRYLASARSAGKS
                     LKFKDQDITIEETTETAFEGVDIALFSAGSSTSAKYAPYAVKAGVVVVDNTSYFRQNP
                     DVPLVVPEVNAHALDAHNGIIACPNCSTIQMMVALEPVRQKWGLDRIIVSTYQAVSGA
                     GMGAILETQRELREVLNDGVKPRDLHAEILPSGGDKKHYPIAFNALPQIDVFTDNDYT
                     YEEMKMTKETKKIMEDDSIAVSATCVRIPVLSAHSESVYIETKEVAPIEEVKAAIAAF
                     PGAVLEDDVAHQIYPQAINAVGSRDTFVGRIRKDLDAEKGIHMWVVSDNLLKGAAWNS
                     VQIAETLHERGLVRPTAELKFELK"
     gene            complement(30177..30249)
                     /locus_tag="VQ865_000783"
     tRNA            complement(30177..30249)
                     /locus_tag="VQ865_000783"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(30214..30216),aa:Thr,seq:ggt)
     gene            complement(30349..30858)
                     /locus_tag="VQ865_000784"
     CDS             complement(30349..30858)
                     /locus_tag="VQ865_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HET3135166.1"
                     /translation="MKKLTIRDVADIAIVAAIYVVLTVTPPLNAISYGAYQFRISEMM
                     NFMAFYNPKYIIGVTIGCMIANFFSFGLLDVFVGGGSTLVFLSLGVWLFAKYSKDYLF
                     NGLIRKDHFFFSILFSISMFTIAAELNIVAELPFFLTWFTTGIGEFASLIIGAIIIGK
                     IGRRIDLSK"
     regulatory      complement(30856..30952)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01054"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class II; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF01054"
     gene            30981..31412
                     /locus_tag="VQ865_000785"
     CDS             30981..31412
                     /locus_tag="VQ865_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HET3135167.1"
                     /translation="MKIPIQKFFNNEILAYLFFGLATTLVSILSRLVIYQLSHQELLA
                     TALANIIGILFAFITNDTIVFKQKKKNRLIRLVKFSLARLSTFLLDLFLTFLFVTQFP
                     HIIGQFVTENIDKINAIETIIAQIFIIIINYILSKAYIFRK"
     gene            31494..31871
                     /gene="mscL"
                     /locus_tag="VQ865_000786"
     CDS             31494..31871
                     /gene="mscL"
                     /locus_tag="VQ865_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HET3135168.1"
                     /translation="MLKNLKSFLLRGNVIDLAVGVVIASAFGAIVTSLVNDIITPLIL
                     NPALKAAKVERIAQLSWHGVGYGNFLSAIINFIFVGTALFFIIKGIEKAQKLTGIKKE
                     KTAEKKPTELEVLQEIKALLEKK"
     gene            complement(31913..32886)
                     /locus_tag="VQ865_000787"
                     /pseudo
     CDS             complement(31913..32886)
                     /locus_tag="VQ865_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254302.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
     gene            33041..34264
                     /gene="pepT"
                     /locus_tag="VQ865_000788"
     CDS             33041..34264
                     /gene="pepT"
                     /locus_tag="VQ865_000788"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000222045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HET3135169.1"
                     /translation="MTYPNLLDRFLTYVKVNTRSDEHSTTTPSTQSQVDFATNVLIPE
                     MKRVGLQNVYYLPNGFAIGTLPANDPSLTRKIGFISHMDTADFNAEGVNPQVIENYDG
                     GVIELGNSGFKLDPADFKSLEKYPGQTLITTDGTTLLGADDKSGIAEIMTAIEYLTAH
                     PEIKHCEIRVGFGPDEEIGVGANKFDAEDFDVDFAYTVDGGPLGELQYETFSAAGAEL
                     HFQGRNVHPGTAKGQMVNALQLAIDFHNQLPENDRPELTEGYQGFYHLMDVTGSVEEA
                     RASYIIRDFEKDAFEARKASMQSIADKMNAELGSYRVTLNLTDQYYNMKEVIEKDMTP
                     ITIAKAVMEDLGITPIIEPIRGGTDGSKISFMGIPTPNIFAGGENMHGRFEYVSLQTM
                     ERAVDTIIGIVAYKG"
     gene            complement(34300..34929)
                     /locus_tag="VQ865_000789"
     CDS             complement(34300..34929)
                     /locus_tag="VQ865_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135170.1"
                     /translation="MSKVNQLLEQIHEEGIRQSLAEEVENLKAATNKADADLDEVNSQ
                     VKDVLTRIASALQQEKENAEQDSQTLVLYQKLYDILMSLHSYLESNNGSDADFDKVDA
                     LLDQLSAKSKDKTALLESTKAILVLNHQIQSKASASEETSPARNAEANSDNTSAENQP
                     NATAESNIEIASDENKPSNTRDSKPAESTSENETTESSTTTGNQEKPVE"
     gene            34894..35115
                     /locus_tag="VQ865_000790"
     CDS             34894..35115
                     /locus_tag="VQ865_000790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135171.1"
                     /translation="MDLFQELIYLAQKTFYFFLAICRRLLVAIYHVLLKQESYNPRLQ
                     GLTEIRNPDKTMFVQDAIRFAQQHGFNML"
     gene            complement(35386..36397)
                     /locus_tag="VQ865_000791"
                     /pseudo
     CDS             complement(35386..36397)
                     /locus_tag="VQ865_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669441.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
     gene            complement(36623..39742)
                     /gene="phtE"
                     /locus_tag="VQ865_000792"
     CDS             complement(36623..39742)
                     /gene="phtE"
                     /locus_tag="VQ865_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtE"
                     /protein_id="HET3135172.1"
                     /translation="MKFSKKYIAAGSAVIVSLSLCAYALNQHRSQENKDNNRVSYVDG
                     SQSSQKSENLTPDQVSQKEGIQAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDALFSE
                     ELLMKDPNYQLKDADIVNEVKGGYIIKVDGKYYVYLKDAAHADNVRTKDEINRQKQEH
                     VKDNEKVNSNVAVARSQGRYTTNDGYVFNPADIIEDTGNAYIVPHGGHYHYIPKSDLS
                     ASELAAAKAHLAGKNMQPSQLSYSSTASDNNTQSVAKGSTSKPANKSENLQSLLKELY
                     DSPSAQRYSESDGLVFDPAKIISRTPNGVAIPHGDHYHFIPYSKLSALEEKIARMVPI
                     SGTGSTVSTNAKPNEVVSSLGSLSSNPSSLTTSKKLSSASDGYIFNPKDIVEETATAY
                     IVRHGDHFHYIPKSNQIGQPTLPNNSLATPSPSLPINPGTSHEKHEEDGYGFDANRII
                     AEDESGFVMSHGDHNHYFFKKDLTEEQIKAAQKHLEEVKTSHNGLDSLSSHEQDYPGN
                     AKEMKDLDKKIEEKIAGIMKQYGVKRESIVVNKEKNAIIYPHGDHHHADPIDEHKPVG
                     IGHSHSNYELFKPEEGVAKKEGNKVYTGEELTNVVNLLKNSTFNNQNFTLANGQKRVS
                     FSFPPELEKKLGINMLVKLITPDGKVLEKVSGKVFGEGVGNIANFELDQPYLPGQTFK
                     YTIASKDYPEVSYDGTFTVPTSLAYKMASQTIFYPFHAGDTYLRVNPQFAVPKGTDAL
                     VRVFDEFHGNAYLENNYKVGEIKLPIPKLNQGTTRTAGNKIPVTFMANAYLDNQSTYI
                     VEVPILEKENQTDKPSILPQFKRNKAQENSKLDEKVEEPKTSEKVEKEKLPETGNSTS
                     DSTLEEVPTVDPVQEKVAKFAESYGMKLENVLFNMDGTIELYLPSGEVIKKNMADFTG
                     EAPQGNGENKPSETGKVSTGTVENQPTENKPADSLPEAPNEKPVKPENSTDNGMLNPE
                     GNVGSDPMLDPALEEAPAVDPVQEKLEKFTASYGLGLDSVIFNMDGTIELRLPSGEVI
                     KKNLSDLIA"
     gene            complement(39953..>40624)
                     /gene="phtD"
                     /locus_tag="VQ865_000793"
     CDS             complement(39953..>40624)
                     /gene="phtD"
                     /locus_tag="VQ865_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtD"
                     /protein_id="HET3135173.1"
                     /translation="YNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAPKGYTLE
                     DLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPQTEKPEEDKEHD
                     EVSEPTHPESDEKENHAGLNPSADNLYKPSTDTEETEEEAEDTTDEAEIPQVEHSVIN
                     AKIAEAEALLEKVTDSSIRQNAMETLTGLKSSLLLGTKDNNTISAEVDSLLALLKESQ
                     PAPIQ"
BASE COUNT        11906 a         8200 c         6717 g        13801 t
ORIGIN      
        1 ttcaaagtca attcataatc ttcaacagga ttgagcattt tatcttctcc tacaatatcg
       61 acataagata cattaaactt ctgacaaatg atgtcaatta attccgtaga gactgaacta
      121 gttccatttt cataacgact caagctattt cgagaaattc ctataattcg tgcaaattca
      181 ggttgtgtta agtcatgtgt tttacgtaag gattttatgt tctttccaat catagtaaac
      241 tcctttattt ttataattca attatagcat aaaaaagtat aacgcaccaa ttttggtgcg
      301 ttatactttt tttctagcct aaactttact tctataaaag tcacctaaag agccataaat
      361 atttattctt gtattaattt tttcgatgcg caaacgatat ctacaaatac atctataacg
      421 attcaccttt taggattttt attgtcaaaa ttgcctttat ctacaaagac aaaatgctta
      481 taaaatagct tgaaatcaag gattatcacc tttttcgttg tagcaacact ccacatgtga
      541 ttattaggct attagcaaag cgtatccaat acctcaataa agtgttgttt ttactgatat
      601 tttaactata ttgtatagtc tactatttaa atctcaatta ggatatttta tagaataccc
      661 aaaattcaac aataactaaa agtaagattc cattgtattt ccttgttggt ctttcatatc
      721 acgaatttta tttttcagaa tattaaagtt acaaatttca tctctaatat cgttatccgc
      781 tctgtagcca ttaatcatct cagtcagagt tttcccttta ctaccattct ttatagtagt
      841 atttactctt tttatactgc tttcaaaagg ctcatatgtt ttatacttaa ttacttcgtc
      901 tttaaaatta aataaaggtg tatccggctt agcattccat aaaataatca accacattat
      961 agcattataa agctgctttg cagtttcatt ccacttttca ggttgtaaat ttccactccc
     1021 tgtattgtca tattcttgtc tattatttac atgagaatca cctacaagtg gattaaaaag
     1081 aggtagccct ttgtgattaa ttagttctaa aaaatccctt gccgcaccca tgcaacactg
     1141 aataacttcc ttcttgccat caattttact ctcagcgata aatacataat attcatcttc
     1201 aatagttgct cctgcatcac tatgtttttg ttgatttgct aacagcttaa tatgtgcttt
     1261 aggctaaact tcaaaatctc taacaattct ttgtcttgtt tcatgtcctc tacaattcat
     1321 ttaagttctc ctttacaagt ttagtaacta gccttattat actatataag atatgaaatg
     1381 taccataatc ttcatcaact agtttttaga aaatcacaaa tccatctgga gagatgacaa
     1441 gctgattctc caattcttgg caattgcttg ctagtgctac tgcttctttc tctaaaagat
     1501 aatcttctgt tgattggttg aatattgctt tgaggatccg tccttcgtat ttccattcca
     1561 gagctactaa atcagatttg atttcttgaa ggctatactt gccatgcgaa ataattactg
     1621 acgcgtattt ccgaatctta atcagcctct tcataaagtt cagcatatca ttgtcacttg
     1681 atacacgttc ccaaggcata caacgacgac aatctggatc tggtcctcca gtcaaggcta
     1741 gctcggttcc gtaataaatg cacggtgttc ctttttgtaa aaagagaaag gctaaggctg
     1801 atttaaccag ttgaacatct tcattggccg tccacaggat tcgctctgta tcatgtgaat
     1861 ccaagagatt aaacatgacc tctgaaatct gctgcttgta atacatagac tctccattga
     1921 tttcatcgat gaactggtct gtcttcttaa ttcctcgtaa gaaatagtcc ttgatactat
     1981 cagataaagg ataattcatg atggcatgga actcatctcc atttagccaa ggctgagatg
     2041 tatgccagac ttctcctagg atataaagat caggattttt agctaaaact gccttacgaa
     2101 aatccttcca gaactgatgg tcaatctcat tagccacatc caaacgccaa gcatcgatat
     2161 taaactcttc aatccaataa gtcgcaacct ttaaaagata attcttgacc tctggattgg
     2221 ctgtatttag cttaggcata tagtcctcga aaccaaaaac atgatagggt aagtctctct
     2281 tattaactag tttttcagtt gtcactggga attgttgaat atggaaccaa tccttataag
     2341 cagactgttc accatttttg acgacatttt tccattgaag agattgcgaa ccaatatgat
     2401 taaataccgc atccagcatg actttcatgc cacgatgatg cgcttgatcc accagttccc
     2461 gaaaggtctc cttgtctcca aaatgacggt caatttcaaa gtaatctgtc gtattgtact
     2521 tgtgattgct tgtagattca aagatgggac aaagatatag tccagtaata cccaagtctt
     2581 gcaagtaatc catatgatca ataatcccct gtaaatcacc accaaagaaa tcatcgctct
     2641 taggtgtgac agatgaatcc cagtctaaag tcccttctgg gtttaataga gcattgccat
     2701 tggcaaatct ttcaggaaat atctgatacc ataccgtatt tgaaacccag tcaggaacct
     2761 tgcaggcatc aatcttgaag ataaggcaac ttaaatccat tcccaattgc atgaagattt
     2821 tctagagaat tttccacaca ccctttatcg ccatacaaaa tattttgacc ttctgtatct
     2881 ctgagctcaa agagatactg gatacgtgca aagtcaactg acacttcaac ctgccaatgg
     2941 tcaaataagg taccagaagt tatcttgacc atttcttttg tatcctgata aaactcctcc
     3001 ataaagataa aagggtcccc atagtgcaag ttgatgcttt caatgtcccc tttcttagtt
     3061 cgaattcgaa tatggagttt cttatcctta taaagatagg catactccga ctcaggccta
     3121 tggtaaatag cactcaattc catcaatttg tctcctaaag tattcattca aattttacgc
     3181 aaacgttttc aaactcaatg aatccagtat actatttttg taaactattt gcaaggaatg
     3241 tccgttgtta aaggaactat cttttaaagt atacaaaaag ccttaaaaaa ggctttctct
     3301 atatactaat cctctttcgg ttttgaaaat acttctactc gctgagctag gactttgatt
     3361 tctacaggta ggttatctga tttatctccg tcaacatctg actccaattc actatctgaa
     3421 gagattttaa tattacgcgc tttgatatac tcgatattat catttgcgac aacatcccct
     3481 tttaataaat caggaatgac ggataatttg gagaatatag aggcatcttt cagaatcaaa
     3541 atgttggcat agccgtcctt gttttcttca aagattttct tatcagcgaa gtaatttgtc
     3601 aaaaggacca aaacatggct agcttcacca acataatttc cattttctgt ctcaacctta
     3661 atgttaaaga cctgatctgt catgacagac ttcatggtat ttacagcata ggttaaaata
     3721 ccgaattttg ttttgtcctc tatttcaaca ttgtgaatcg cctcaggcag agaaccgata
     3781 ctaaagatat aaccaaaata gttgtcattt gctttaccga tatcaatctt attgattaaa
     3841 tcaaaatcca gttcgtcaat tgcgccatcg atgtcttgat tgatttccaa aagttttgta
     3901 atgaggttac ccgtaccgcc tgggataatc cctaacttag gaatgtagtc tctctcatca
     3961 atacctgaaa tgacttcatt gacagttcca tctccaccaa acacaaccac tgcatcatac
     4021 tgctcacgag aagcttcttc agcaaaatgt gttgcatcca gcgctttttc ggtaattttg
     4081 gtttcaacat attcaaagta ttcttttgct ttattctcca gcttttcttt gtaatccaaa
     4141 gccttctcgc caccagaagt agggttgata attaccattg cttttttcat tgattttatc
     4201 cttaatttta aacagaaatg tttacatttc gtcgtatgca agtaaatgta atcctattat
     4261 acaatgaaaa tacagaaaag agaaatctga catactggag attaatacgc ttttattcta
     4321 ttttcccatc gcctaactac atcctttaag ggttcatcca agtaagaata ggccttatcc
     4381 ttgatccaat caggaatacc gtaagctgcc tctgctatgc tacaagtgat tgctgcgaga
     4441 gtatcactgt cgccaccaag tgagatggca tttcttatcg catcttcgaa gtctctactt
     4501 tcaagaaagg cgataatggc ttgagggaca gtttcctgac atgtttcgtt aaaacgatag
     4561 ttaggacgga tttcatctaa agtttgagat agattgtaat cgtattcttt ttctatataa
     4621 tccttaattc gtcttttaca ctctgtagga ttgtcgttaa ttgattgctc gtactctcta
     4681 caataaccac caaagtaaaa acgacataga aagatagcat cagctgtagc catagcgcct
     4741 ttgacacctt ctggatgatt atgagttacc tctgcagaaa gactcgtaag tcctctagat
     4801 gatggccaca taccagtttt cgcataaaaa ccacagtcca tgatccaagc acatggagaa
     4861 atacgcatag ctgatccatt cccaaagcta ttataaggct cacggttatc gctgtttagc
     4921 catgcattaa accgagcacc gtaatcagca ttcggataca ttctgccata tttcttcatc
     4981 gcgtcaatga aatcgtcttt ttgtccacca ttcataattg cttctgcaac agcacaggtc
     5041 ataaccgtgt catctgtaaa aaagcagtcc ttccgaaata aaggaaagtc ctttgttttg
     5101 atattgttcc attcgtaaac agaaccgaca atatctccaa taattgctcc aagcatcaga
     5161 ttcctccttg ttcattttga tgctttttat attggttatc taccatattt attttagaaa
     5221 ataacatcct gttggatttt aaaaatttca tttttttcaa aatagggttt taccatttct
     5281 ttccacctag ctctatgaaa attgattgat tttaaaggag ataggccata atttcccaat
     5341 gcataaccat catttacttc aacaacaagt gttctgccat cgcgagtaac accgatatct
     5401 agtccataag ctattggcgc atctttccaa catgatatcg cttcatcaat tacacttgca
     5461 tcaaattgtg catgataatc acctgtatag ggtcgaacat ctaatacgcg accatctaac
     5521 acaaaacaac gccattcagc tatgaattct acaacctcac taatccatat aggatagtcg
     5581 aaaggtagac caatacctat taaatcatgg gttccattaa caactcttcc agtaaagact
     5641 tttgaaccag ctttaggctt aataaatttt ccccaattat caggtatatt cacaatctct
     5701 cctaaaatac cagcataaat ctttcgacca taaaactctt taagctcaat aggatagtca
     5761 tgaaccggaa cgtttaagcc catcattttt agtaatgctc tagtctccat tatataatct
     5821 acaactatat cttcacttgt taactctttt atttcagaaa aagattgata taaaataact
     5881 tcttctcctt gtaagtaggc acctacttga gcattgtatt tattaattga aacctcactt
     5941 ggtaatttac tttgtctaat ataaacaacc atttcatcac tcctatatca ctagtgttac
     6001 accaatttgt aaaaaataat agcaattttg ctcttatttt tttgagtaaa tagcccccat
     6061 aatatcatcg aaataatcaa cggtatttag gagtaattca ataacctggg actttgttag
     6121 tcgcattccc cttctatctc tagcatcttc tactaaattt tcaagtttct ctagattttt
     6181 atcatccaag ctaatcatta ttctattttt atcggttgcc attttcatca cctcgagtta
     6241 attctatcac aggtgtaaca cttgtgtcaa ctggctttta taatacatta gtttaaaagt
     6301 ggagaggatt tttaacacag taactttaaa tctttggtat taaaaaattt tcacaatatt
     6361 tatagaaata aaatctgtct caaatcagtt atcaaatcta gtataaatta tgagcggcta
     6421 ctctaatact ttccctctaa acaagaaaaa gacttacact caagggtttt cttccccccc
     6481 cttcgttata acgttttgac tcttttacta gcaaaggtat atactcacaa ggaactttgg
     6541 ttgactattg aatctctcca acttcttctt taacatatcc ttctacatct tcaatctcta
     6601 caaacattgg gtctaagtga cacaagaaat gccaaacttc gatccctttt tttctgtaaa
     6661 gaatcgcttc accgtcttca cttccgaaaa agcttctgtc gatttcatat ccgcggcttt
     6721 ctaagaagtc ttttgcttta cgatagttcg tttctcttgt ttcgacatag gctttaactt
     6781 catggttgtt aacgacatat gcatcaattt ttgaatatcc ttcgatcact ctatcatttt
     6841 tgagggataa atttgaaatc tctttccaaa taatgtttac attttcctca ggatcgaaca
     6901 taaatttaga taaaggaaca atatttccgt taaaaataat ttccatataa tccggtatgt
     6961 ttttaggatt aaaatactcc acttcaaaac catcttctgt ttccagagtg tatcccggga
     7021 tttgagctac aaaggctttc ccatcttcta tggaatcaaa tgctactaaa tctttagaat
     7081 aatcattttg gtacaattcc aatataacca tcgataatct ctccattttc attatcaggc
     7141 taatgtaaat aagcacgtca cctgaccaat tcaggctctc tgtatcatct catcatattt
     7201 cctacttact ttacgagtcc tatacccaga acacacctta tcgaccttcg gtctcacctc
     7261 gtcgcattgg ctgaacatct acttttactt cgctgatgct tcaactcgta caagcagtga
     7321 taccgcctca gcgtgatgcg tcagtgggac tcaaaaagtt tggggaacct tttgaggatt
     7381 aactacgttt ctctaataaa cttacacatt caacttgttc atcattgtcc aaatctatgt
     7441 tgagattttc ttctataatt ggtagcttaa aagtaatgga ttttagccat tgtccgttag
     7501 attgtttttc ttcataaact tgaatttcag aaatcaaagc tgaaattaac tgcctacgct
     7561 ctacatcatt catgacttta tagagcttat caaaatagat cagaacctta tatatgttat
     7621 ctcctgtaag cttttcagct tcaatagtct gtttctttgc tttcgcatca attagtgatg
     7681 attctaattc atctattttg tcatacatac gatatagtct atcatctaaa tcctgtttcc
     7741 ttctcttata atgcttatct tcaacatcta aattatctat ttcctcaatt agcttaaact
     7801 ttgtagaatg actctttctc aattcctttt ggtaattatc tatttctttt tctatttcag
     7861 aggtatccac cttcatgttg attttttctt gcatcataga agcaaatttc ggattactta
     7921 ctatcttgac aatcacctct gcaacagcat catctaacaa ttcttctcta atttgcttac
     7981 tgaatgtaca cttatgacct cttatcatct gcctatggtt acaaccatag taataaaaat
     8041 ctttatactt tgtgccatct ttctttttct tgatacactt gttcccaaac attcccactc
     8101 cacatatcgg gcattttaca attccagaaa gcaagtgtgt gcgtgtatct tttcctttat
     8161 tcacatgctc atatttcttt gcttgagatt ttagcttaac ctgagcagct taccaaactt
     8221 catcggaaac tatagcttca tgtatccctt cagatattag atattcatct tgttcaacct
     8281 gcttatattc atttcttgta ccatgaactt tttctaaagt tcttcttcca aatgctattt
     8341 tcccattata tacaggattc tttaatatct ttcttataag acctgcatca aacaaaggat
     8401 tcttaccatt ctgtcttggg atttttctaa ttccatgatt ctctaagtat ttagatatcc
     8461 cattggctcc tatcgtagta tttacatact ggtcgaaaat cgttcttatt gcaactgcct
     8521 cttcctcatt tataaacagc ttgccgtctt caagtttata tccatacgga gcaaagccac
     8581 cattccattt tccttccctt gctttttgaa tgcaaccttc cattgtttga atacggatgt
     8641 tttctctttc tatttcagcc acagctgata aaacagaaat cattagtttc ccagcatctt
     8701 tagatgaatc aatgccatct tcaacgcaga taagattaac tccataatcc tgcattatct
     8761 gaagtgtaga aagaacatca gcggcatttc ttgcaaatct tgataactta aacacaagaa
     8821 caaaagatac tccatctttt ccagatttta tatcttccat cattcgattg aactgtattc
     8881 taccttcaat agacttgcca gacttcccgg catcttcata ctctccaaca atttcataat
     8941 cgttgtaaat agcaaaagct ttcattcgtg atttttgtgc ctctaacgaa tacccctcta
     9001 tctgtattga cgtagatact cgtgtataga ggtatacttt tattttttct tttgacatag
     9061 tattaacctc aatataattt ttctatatca tatataattt ttttaattta agtttggact
     9121 atcatttcaa gtatattata acacttttat tagtccgtct caatttgtgt ttttgccatg
     9181 tcaaaactat ttttcatctc ttgatttttt gctggcgttg gatcgggtag attatctaaa
     9241 tctaaagcac cagcatattt tgcaatcaga tttgctatta aatcagccaa tccattccag
     9301 tcattgtcca atatatacct cctctaaagt tttatatcta ataattattt gtttaattaa
     9361 gttttttgac attgacaagt gctttggatt agcaacatag gaatctcacc tccgcctcta
     9421 ttccggatga gccggcttca accttagaag tatcattatc ctcattttct tcatagcgga
     9481 tagggtatcc ctccctatat tcaaactctt acttatcgct cactttcttt ttacttagca
     9541 gaactttttt tgccgaatta ttcagccgaa agatcttgac ggataggtta ttacgctcca
     9601 aaaataatta acgtcttgtc ttggtctatt caattgttaa ggttcaaaat ttatcgagag
     9661 ttattaatct ttttaaaatt tgaccatcag aaaatattta tcttaatgta acaaaattct
     9721 ataaattacc ctcttatact taacagtgaa aagaagtctt tcttggtaac caattttgaa
     9781 atagaatttg cttatataaa aaggtcaaat tcccactgca taagtagcag tgaaaattag
     9841 accctcttgg taactgtcat ctaaaagtct tctagcattt ctttaatttt ctaatcgcct
     9901 ttaaagtgtc atatttatat ttttttatct ctggcatact ttgatacctt tttagactta
     9961 aagtctttaa tagtgccttt ccacctcttt ttatctataa agattctcct acatcataat
    10021 tcattttttt atttaaacct ttctgtctta gtttgtcttt atcttcttca taccatttta
    10081 agattgtcac atagtggttt tgataggtct taccactgct ttccatgtat ctggatagtt
    10141 tatttatcat tatatctgtg tgtgagttta atttttcttt tagattttta tattcttctt
    10201 tgcttaacct tacatttttg aattctccat aaaaaatggg ggtggacttt ttatctatct
    10261 ctccctctct ctctttatct atctctatat ctttccatgt aattccaatc tggagtacct
    10321 ctactgtcta tcggtaattt aattttgata tctggcaata ctgtgctaga tatttgatct
    10381 ttatattcag tattttttaa agcttgccta ataattgaag ttaaatagaa tgctacttct
    10441 ttattcaatt ctttattttt taattttaaa caatgaattt tcatatctag gcttgcttta
    10501 tatttatgat aaaagactgc tcctaaaaat gaaacagata taaaattttc aaaaactcta
    10561 taatttttat catctatatc ttcgtagtaa cctaagatac cattgtcaat atttgtagca
    10621 ctaattctag gagtttttcc atcgagtaaa tatctttttg gaatagatga gcctgttggt
    10681 acttgactcg atttcccctt tttttcggta ataaatattt ctttttattt tgttgtccga
    10741 tatttttcct acctgtcctt tgtaggatga gtattttcta gattttcttg aataactttt
    10801 tacttgaagt tttagctttt gaactagtcg ttgtactttc tttttgttta ttatcagtcc
    10861 tgatcttttt aatattgctg ttattctcta tatcctattt ttcattcatg atattctttt
    10921 actaatttta tcttaaattc tgtgctgtat ttgccattaa aaaactgacc tcctttagtt
    10981 agttttttgg cctaactttt gagggtcagt tcaaaatttg cgacttttaa atgaattccg
    11041 atattcaatt attaagagct aacatggtgc ttgccaatag gaatcattag aggcgaattg
    11101 gaaatagggt cacgtataat ttttgcttca agattaaaga tatctttaac tagtttatca
    11161 tttagtatat cttcaggctt tccctctgca acaagtttac cttctttaat tgcaaatagg
    11221 taatcagcgt atcttgctgt tagatttata tcgtgcaaaa tcatgcaaat ggttgtctta
    11281 tatttttggt ttagatcagt caagaggtct aatagttcta tttgatatga gatatccaag
    11341 taagtagttg gctcatctaa aagtaggata cttgtatctt gggctagggc tagagctatc
    11401 catactcttt gcctttgacc cccagaaagt tcttcaacta ggttatttgc tagatcttca
    11461 acattggcct taaccattga tctgtttatt atttcaaggt catcttttcc aagactctta
    11521 aaaggctttc tgtaggggaa acgaccacgg cttacaagat cagctactgt tattgattca
    11581 gggattattg gagattgagg taatatagct atgtgttttg ctaaatcttt ttctttataa
    11641 gaattaattg atttattatc gagcaatact tctccctcta atggctttat aagtcgagac
    11701 aaggttttaa tgagtgttga tttcccacaa ccatttgacc caataataac tgatattttt
    11761 tcttcaggta tttttatatt tatattttcc aagattattt tttcatcata accgcaggta
    11821 agattatttg accacagacc tttcattata tattcctcct gttcattttt attagtaagt
    11881 atattaagta tggtgaacct aacaagccag ttacaacacc tactggatat ctagctggta
    11941 aaatattttg agagaatatg tctgataaca aaactagtaa aattccaacc aatccagcta
    12001 atattgggct tcttttcttg ccaatattta aggctatggg accagctaaa aaagatatac
    12061 aagctattgg tcctgtaatt gaagtagaaa aagcagttaa agatacagcg caaaaaatta
    12121 aaacaagcct tgaaagctcg ggatttgctc caagtccgat tgctatttct tcaccaagtt
    12181 caataatttc tagtctttta ttaaaaaata aaactaatat agtagcaata atacttacta
    12241 ttagaacaag aggtatgtca tctaactttg taaaagataa agagccactg agccatctca
    12301 taacttcttg taattcatat cttgctactt tcaacaataa aaatgaggtg cctgctcttg
    12361 tgacagcttg aaaaccaatg cctaatatta tcagtcttgc tgctgaaaaa ccatcttttt
    12421 tagctagtaa aaataatatt aaagatgatg ttagtccaca agttattgaa ataattccag
    12481 tagttaaact atttgttttt aataccaata tgcaaaagac cgctgcaata gatgaagaac
    12541 ttgtgacacc gattatatca ggacttgcaa gaggatttct taacatagtt tgaaagataa
    12601 atcctgccaa tccaaaagac cagccagcta taattcctgc taataatttt ggtaatctaa
    12661 tttccataat cgaaaaacta gctccaggaa cagtttcact atttaagact ttaatcaaag
    12721 ttgaaaaaga ataactttca tctccgataa gtaaaatgaa aaatgataga ctgattatta
    12781 ttaataaaaa tagtgaggaa aatagtgtta ttctattttt tcttttttga atacctataa
    12841 ttaaattttg cattagttat taacccctct atttttcata gttacataaa taagtactgg
    12901 acccccgatt attgcagtaa ttatccctac ttcaatttca cctggtttac ctaacatacg
    12961 gccgattata tcacatataa gcaagagctc tgcacctata aaagatgaag aaatggtcat
    13021 tgtgcgtata tctttgctta taaataagcc acaaaagtga ggaactataa gacctacgaa
    13081 gccaataggt ccaccaattg cagtaatact tgaacataaa agcacacttg caattattgc
    13141 aagtgatctt atcctattaa cattaactcc aagaccaaca gccatttcat cacccatagc
    13201 taaagcgttt aaatctgatg aaataaatat agctatcaaa tgacctaaaa ttataaaagg
    13261 tagtagtgta gatatagaag ataatgtagc tgctccaagg ctacctattt gccaaaatct
    13321 aaatttgtct aagacgttat tattcggtaa aattaaaaaa cttacaaaac tgcttaaagc
    13381 catactaaca caagttcctg ataaggcaag ttttataggg gtaaggcctg cttttccgct
    13441 tacagcaatc gcgtatacaa aaattgcact tactaagcca ccaatgattg caaaacttat
    13501 atggcttatg cttgatgaaa ttcctaaaaa agaaagacca attactacac taagacttgc
    13561 tcctgtgttt ataccgagta tacctggatc agctattggg tttctagtaa ctgattgcat
    13621 caatacaccg cttatggcaa gactagaacc tgctaaaatt gcaaaaatag ttctaggtat
    13681 tcttttatat ataattgatt taataaaatc atcatttgta ttacccattc caaaagctgc
    13741 taaaaaatct ctgatattaa tttcttttgt tccaagcttt aatgacaaaa atattgtaat
    13801 aagaagacct aggcagatta caaaaattat gcctaggttt atttgttttt tatttcgcat
    13861 ttttgcatgc atttcctaaa agatttaggt attcttcaat agtatagttt attgaaagtg
    13921 gtgttggagt gcatgaggct gctaacggtg tattatctgg aattacagca acggcaccat
    13981 ttttaattgc atttatttta cctaaaagag gatctttttg taaagcttca agagttttat
    14041 catcaccata agttatgatt acatcagcat catttatctt atttgcttct tctgcagaaa
    14101 tttcctttgc aaaactatct tcactctcaa attcttttaa tgattcaggg aaaactagac
    14161 ctaaatctgt taaataattt gctcttggat ctttgctagt ataaatccag aattttgatg
    14221 tatctgcagc attaatcata gtaaataata ctttttttcc tttgattttt cctttgattt
    14281 ctggatgttt ttctaattct ttggatatac gagcttcagt atttttgatt aactcatcac
    14341 cttctttttc catacctaag gcttttgaat caattttaat catatctctc cataaagttt
    14401 gccaaggttt agatttgtat gctgctacag gagcaatttt tgatagagtg tcataatctt
    14461 ctttagttat accagaataa cctgctaaga taacatctgg tttagaattt gatattgctt
    14521 caaagttaag tccatccaaa tcgtcaaata ggttagcttt accatttagt tctttgattt
    14581 tttcttctgt ccatggtaaa actcctttat cagcacttac accgtaattt gcttttgaaa
    14641 atccaacagg aactattcct aaagctaatg ctacatcatg atttccccaa gcaatagttg
    14701 caactctttc aggtttttta tctaatatag tttgaccgaa agcatgatct aaaactattt
    14761 tatcaggcgc atgctcttta gaagtatttt cttcattttt aacagaatta gaagaacaag
    14821 cgctaaaaac tatacacata gctaaaatag ctattagaaa aaatttgttt ttcataaaaa
    14881 ctccttaaac atatttcaag tctattgtat cgataataat tatcattgtc aatagataca
    14941 gttacaaatt taataatata attttttcaa aaaaggatct agtttttatt tttagttaaa
    15001 ttatgtctat atttttcatt aactcatcaa taaaaatttg tttgctaata tctctttctt
    15061 ctgattttgt ttcaaggatt attgctacat cattcatatt tttaggtaaa taccaaccat
    15121 ctggcttatc tgaatatccc ttgaagccta attgattaaa agtagttatt tgaccagtac
    15181 cttgattgat gttttcttca acttcattaa agcctatact tctcttgcat aatccctaac
    15241 ttgatcttct gtccttaaag tcattttcta ttcctcgtca ctaaaattat cttcaaaact
    15301 aataatatca ttaggagtgc aagataaagc cttacatatt ctttctaaat tcttaaatgt
    15361 aattggttta tcctttccca tttgtgccat aacatttgtt gtaagtcctg ccatagctat
    15421 tacatctgtt ttctttagtc ctttttttgc taactgtatc cataatggtt tatagttaag
    15481 tgccataata tccctctttt tttcttcatt agatttattt aattatagca taaatattga
    15541 ttttattcaa tcttacattg atttagtgat ttgttttaga gaatttgttg tgttattccg
    15601 tccttatttt gccataaatt gttttaagtg ggacctctta tccttaccat ttttacctcc
    15661 taattttgag tataaaaaag acgatagagt ttttaatttc tatcgtctga gatttacata
    15721 ttaaattttc atcacaaaat aagactcttt aaagaatctt taaattcatt ggtatgctgc
    15781 ttacaatatc cattattaaa atggatattg taagcagcat accaactatt tattttttga
    15841 gttttaaact ttggtagaag tcttgaactc cttatattta cataactatt tgcctctata
    15901 actgttatga cacgaaacca acaagcaagt tcaagcacct ccatatcttt attcaaatga
    15961 ggactaagat attcacaaac tttatcataa acctctttat cttttttcat aaaaggggca
    16021 tacaacttag caaatttatc ctaaaatttt ttgttgcctt tatcaatcat ttcaacgctc
    16081 ctttaaatat aaaaatgatc ctatcaatct ttatattgag cctattttct aattgatacc
    16141 ttgcaagaaa ggaataatag ctgttcctat accaagtagg aatgtaataa atgcagaaag
    16201 tcatatactg tcattctttt ctattaaatc attttgaagt gtctcaaagc atccatgatg
    16261 gcttcttctt tttcaggtgt acactgtgga ataatttgtt tatccttttt agacttgttg
    16321 taatgttctc gtaattctat tccacatttc ttttttatct gtgcaatata taatgtcgaa
    16381 acttttaatt caaatttatt ccaaacatat tctttgattt gagcatatgt tgctttgctc
    16441 tccgcacttg tcaaatccat ctcatccagc tcaatttcaa cacttatgtg cttatcgaca
    16501 tcaagtttgg acaaaagtgc taccgtctcg acgtgatgcg tttgaggaaa tagatccacc
    16561 ggctggactt tcttcaattc atatcccaat tcttggtaga gtttgatatc acgcgccatg
    16621 gttgcgacat tgcaggagat ataggcgatg cgatcggctc ctgtttgggc gcttgctttg
    16681 ataaagcttt ctgtcaagcc cttgcgtgga ggatcaacca agataacggt tggttgaatc
    16741 ccatctttaa gccaattctt catagcattt tcagctgtgt cacagacata gtgggcgttt
    16801 gaaatattgt tcagctgagc atttttttta ctattctcaa ccgcttctgg aatcagttca
    16861 acaccgtaga cttctttgac atgcttggcg actgataaac caatggttcc aataccagaa
    16921 taagcatcaa taaccacgtc atcttttttt aactctgcaa agtcaatggc tgtttgatag
    16981 agtttctccg ccatttcagt attgacttgg taaaaggctg ggccagcgat ttggaagtca
    17041 tttcccaaca tctggtccgt aatatagtct tgaccataaa gagtgcgcca ctccttacca
    17101 aaaatcgcat tggtattctg gtcgttgata ttttgcatga cagacacaat ctctgggaac
    17161 tgcttgataa cttgttcaat caattggtca acacgaaaaa cttttggacg agttgtcacc
    17221 aaaacgacca tgatttgtcc tgaatagtga ccacgacgca ccacaagatt ccgaatcaat
    17281 ccagactgtt ccttttcgtc ataaggtttt aaatcaaaac gacggagcag gcctcgaaga
    17341 gctactacga cttggtcaat gacaggatcc tggataaaga aatcttcaag gggcatgagg
    17401 tcgtgcgaat tcttacggaa aaatcctgtt tccaagacac cattcactcg acgaacgggc
    17461 acctgcgcct tattgcgata cttgactgga tgttccatac caagcgtttc agcaacttct
    17521 acatctgcaa ttccagcaat cttgtagaga ctgtccttga cttgcttggt tttaaacttg
    17581 agctgttctg gataagaaag gtgtcctaaa tccgcgattc ctgaacgcag gtaagccaaa
    17641 tctagatctt gattacggtg tggtgactgg acaaggtatt tttcaacttt tccaaagcca
    17701 atctttttat tgaccttgag gacacgcatg agaatttttt cactcggtaa agcattctct
    17761 acaaaaaaga ccaaaccatc taccttggca actcctgccc cttcatgggt caagtcaaca
    17821 atttcaactt ctacaatatc atttttcttt aacattcttt tctctttcta ttggccgaca
    17881 aaaaagacgg taacgttacg gttaccatcc attataccat gaaatttctt aagaaccaaa
    17941 actcttgaag aagttgacaa gggcttgcca gagggagctt aagaagttac caccgtcctc
    18001 tagcgcctta tccgcatcaa agttaaggtt gatattttta aaactgtcgc cagcttgtga
    18061 tacgatgctt tgtttaaggt catttagggt tttagtgaaa tctgcattgc tgaggatatc
    18121 actctttgag agattcaagg caaaattgat gatgatattg atctggtttc ctgttatgac
    18181 ctgatcaagt ttgtaatttt ttaaggtatc ttcaacaatc ttgcggatat cttcttctgt
    18241 cagatttccc ttgctttctt tagctttggc gagtcctgac ttgatatcag ctagggcaac
    18301 gtttaattta ttagcatcat agcctgattt gtccttgttt tcagcattga tatctgacaa
    18361 agcttttagc tcttcttgag ccaaatcttt attagcttgt ggcaccttgg ctccattagc
    18421 ctctagcgaa tagtaaatcc ctgctaaagc actttctcct gtaactggaa taggggctgc
    18481 tacagtgatt ttggcatgtt ccatacccag cgttactgct gcgtttcggt acatatcctg
    18541 agtcacctta gtgatatttt ctggtgtttc aatcttgacc tcaagtggcg atttgtcacc
    18601 tagcttttga atcttggctg atgaatacaa ctgtaagcta gagtcattgg ccacattcat
    18661 gattttagaa taaacatcag gtgtcatggt cttgagttct ttggtatctg ttgaggcatt
    18721 gtagcccagt tttttaagag tttgattttt ttggtcttca gatagggagg aacctaggac
    18781 atattcaggt tggacatagg tttcatcgat aactttttga acatctgttg ctgcatggac
    18841 gctattcata gctgttactg cccacaagac cgcagcacta gtcagaaaga gtttctttct
    18901 catagggaat ttcctccttt acttctttat agtaatatat ctatcttaaa gaaaacttat
    18961 aacaaaaaca cctggtctag ccagatgttg aaaagagagt gaaacatttg atgatgtaaa
    19021 ggttaagtcg tacctgtcta gaataataat aatttcctcc atttacatag agttcagcac
    19081 cgtgaaaaat ggaaatgggg tgaatataac tataagtctt tccagtcgta ttaccaagca
    19141 agggggcaac agtctcacga gagtactgtt tggctagagc caaggtattt tccttgccat
    19201 tttgggcgat aaaatcgata taggcaggtc caaaattata ggcttgaaca gctgtccaga
    19261 tatctacacc cttcttctgc gccagataga gattgcctgt cagagtttga atgccttgcc
    19321 gaatgctaga ggcattatca ttgatggtgt tggtggaacc acttgcagac tcactagact
    19381 gcataacatc gccttctttt ccttttgttt cagtataaat catagcaagc acaagctctt
    19441 cgtttgctgg ggtgtctttt tcactcaaga tttctcgcac catgggttga taggtcatga
    19501 cttgtttgac atcttgatga acgcggtaag ctttatagcc agcaaaaagg aagactgcta
    19561 gtacaagcac tcttcgaatt cgtttaaaca ttatttactt tggatatcct cgatattttt
    19621 gattaagata gagtaggttc cattttcgtt ttggataaac tcaacagact cggcgtcttg
    19681 atagacgtta ttgggaacga tgagctcaat tccatttgat aaggagagtt tttggttttc
    19741 aaatttcttt aattggcgac ttgcatcaat ttcatcaaat tgaacaggtt ctggtacggc
    19801 ttctttgact tggtcaataa agctcaaacg agccgtcaga ttgttgtcaa aaaggtcatt
    19861 agccaatttc tcaggtgaca attcattgct ttcttctagg ttgttgaaaa tcgctgattt
    19921 gaccttggat tgaaattgaa aatcatctgt gttaaaagat tcagcaattc tctgggctgt
    19981 tttttccagt tccttgatag attttttagg agaaatctta ggagcgacag caagaagatt
    20041 atctgaaaaa tagttcaaaa aagtcccgtt gtacttgatt cgtttttcaa tcaggtgata
    20101 cttgcgactc tgaagattga ccaccaaggc ctcgtcagca cccgttccaa atccaggcag
    20161 gttattctga gtcagcttga ttggattatc aacttctcct ccgaggtggg tcaaggtctc
    20221 ccgcagggca attcgcaaga aagcgaaatg ttctacacct tctttagaaa attgaacaaa
    20281 aatcaagtca ttggtcttga gattttcaga aatgctaaac tcctctttcc agagattagc
    20341 cagcgttact gatgtctcca acaaatcgtc tgtaatatga ttgaagaagg gattttcttc
    20401 ttcgaaaatc ccagtcttgg cttcatctga atacacatgt tcaatttttt tacgtaggta
    20461 ttcttcgatt tttggagtaa tattgagaaa cttatctgct aagaacagct cggtatcatc
    20521 cggactgaac tggtgaataa tggctttctt aatataaatg tccataaaag ttttattcct
    20581 cgtataatgg gaaggcatct gtcaattctt tgactgcact tctcacttct tctaatacag
    20641 cctcattttc tgaattctta agggttttaa tgatgagttc agccactttg cgactttctt
    20701 cttcaccaaa tccacgtgca gtaatagctg ctgctccgat acgaatccca cttgtcttga
    20761 atggtgacaa ggtttcgtaa gggattgaat ttttatttag ggtaatattg acttcatcca
    20821 gcaagttttg agcaactttt ccgttttcta caaccttagt cacatcaaca aggaagagat
    20881 ggttttcagt tccacctgaa ataatacgga aatcagggtc ttgcaagaag acatctgcca
    20941 tagccttgct gttcttaatt acattggcag catattcctt gaaagctgga tccaaaactt
    21001 ctttgaagga aactgcctta gcagccacaa catgctccaa aggaccaccc tgaataccag
    21061 ggaaaatagc tgaattgatt ttcttagcta aatcctcatc attggtcaaa atcaaaccac
    21121 cacgaggacc acgaagggtt ttgtgggtcg ttgttgtagt gatatgagcg tatggcactg
    21181 ggcttgggtg aagaccagct gcaaccaagc cagcgatgtg ggccatatca accataagct
    21241 tagccccaac agcatctgca atttcacgga attttgaaaa gtcaataatt tgagaatagg
    21301 ctgaagcacc agctacaatc agttttggtt ttacttcttg ggcttgtttc aagatagcat
    21361 caaagtccaa aagttccgtt tcaggatcca cactatagga aagaaagttg taggtttgac
    21421 cagagaagct aactggagct ccgtgggtca agtgtccacc tgctgccaaa tccattccca
    21481 taaccgtatc acctggctca atcaaggaca tgtaagccgc acagttagct tggcttcctg
    21541 aatgtggttg gacattggca aatttagcac cgaaaatttc ttttgcgcgt tcaatagcaa
    21601 gagtctctac aacgtctact acatcagttc caccataata acggcgtcct gggtaaccct
    21661 cggcatattt atttgtcaag atagaccctt gagctgccat aacagccttg gaaactacgt
    21721 tttccgaagc aattaactcg atattatttt gttggcgttc ttcttctttg gcaatagcat
    21781 tccagagatc agcatcatat gctttaaaat catctttgtc aaaaatcata ggtcttctcc
    21841 tttattgtgt gactagtcca ttagtttgat tttacaataa gaaaatcaaa ctaaaagatg
    21901 cgaataaacc gtttctgcat tttatcacaa gtatagccaa ctttttcata aaatgcatga
    21961 gcacccagac gatgattggc agaatttaag cggataaacc cataaccaca tcttttggct
    22021 tcttgttcca acccttgtag taaactttta ccgatacctt gaccttgcgc ttgaggtgaa
    22081 actgctaaag ctaagatatt aaatcctgct ttggaataga gtgattcgta aacttcagcg
    22141 tggacatatc caagtaagac atgattagct gcatcctcat agccaagtag gaaatgatgg
    22201 gaatcctgag acagtctagc tagttggcta gccgtttcct ctggactaaa agtataaccc
    22261 aaagcctctt ggttgatgtc acatatcgct ttcacatctg tttcttgcaa atctcttagc
    22321 atttcaagcc tcctcaaaag aaatctctgg caaccgagca agaatatctt ctcgtttaat
    22381 tgcgccttgg cgtaagattt tcaccttgtc tccagacaaa tccacaatag ttgaatcctg
    22441 tccagttaga aaagcatcgt cttccagacc cagaacctct tggtcaaaat ccttcagaat
    22501 ttgttcaaag gttacaccac ttgcctgacc tgagatattg gcagacggcc caatcaaggg
    22561 acctgtctct cgaattaaat ccagtgtgat agggtgactg ggcatccgaa atccaatagt
    22621 tgcaaggtca gaatttaccc aatagggaac tcggtcattg gcttcgagaa taatggtcaa
    22681 gggacctggc aaaaaggtct ctacaagttt ttgtagataa gctggctgat tcttagaaaa
    22741 gtgcaagata tcctctaaag tggcaacatt gagattgagc gccttgtctc taggacgacg
    22801 tttgagctgg taaacatggt caactgcttt ttcgtctaag gccttggcaa aaagaccata
    22861 aaccgtctct gtaggcagaa tgacagctcc accattttcc aactcttgtc taatcctgtc
    22921 catcatcaac cacgaccatc ctatcttgac caaattggtc cttgagtgtt cgaactcttt
    22981 tttcaggaag atgtttccta aaaagttcgg gaacactttg accttgcttg tatccaattt
    23041 caaggtaaat cttaccacca tccttgagat agtcttttgc atcttccgca attctacagt
    23101 aaatagctag gccatcctcg tctgcaaaga gagctagatg aggctccgaa tgcaaaacat
    23161 tcaagcctac ctctgactca tcttcacgag agatataggg tggattggat acaattatat
    23221 catatttttc agaaatttct gcaaaacaat cagatttttt aaaaaatata ttaagatttt
    23281 gatcgctagc attctctgat gcaagctcta aggcctcttg agaaacatct gctgctgtca
    23341 ctgaccaatc tggtctattt tttgctagag cgagagcaat agctccacta cctgttccaa
    23401 tatccagaac tgagagattc gtctcaagat tttcagttag aataagctcc actaactcct
    23461 ctgtttctgg acgaggaatc aaaacccgtt catccacctt taaatgcatt ccataaaaat
    23521 ctgcctgtcc aatgatgtac tgagctggct tgtgagctgc tagttgctgg taaatatctt
    23581 ctacaaattg tttttcttcc tctgttgtca cctcctgctg gagggcaaaa ataaagtctg
    23641 taaaagatag atttttcaga ctacgataga caaaagagag gctttccgct tcctctcctt
    23701 gtcttatcaa ctcttcttca aaatttgaaa ataattgagc taatttcatt atttgtttaa
    23761 ttcttctagt ttttgtgttt ggtcataaag caccaaggca tccacaactt cgtccaattt
    23821 accagacaaa atcgtatcta gtttttggag ggtcaagccg atacggtggt ctgtgacacg
    23881 gttttgtggg aagttataag ttcggatccg ttctgaacgg tcaccagtac cgattgtcga
    23941 cttacgctca gcgtcttgtt catcctgagc aatctgagca aagtggtcag cgacgcgtgc
    24001 acggataatc ttcatagcct tctcgcggtt cttctgctgg gtacgttctt cctgcatctc
    24061 aaccttgata ttggttggca agtgaacgat acgaacggca gtcgcaacct tattgacgtt
    24121 ctgtccacca gcaccagagg cgtgatagat gtcgacacga aggtcttttg gatcaatgtc
    24181 gtattcaacc tcttcaactt ctggcataac aagaactgtc gctgtcgaag tatgaacacg
    24241 gccttggctt tctgtcacag gaacacgttg cacacggtgg gcacctgatt catacttaag
    24301 cttagagtat acagactgac ctgaaaccat agcaaccact tctttaaaac caccgacacc
    24361 attcatagag gcttccatga cttcaaagcg ccaaccttgg gcttccgcat acttttggta
    24421 catagttagc aaatctccag cgaaaagtgc cgcttcgtct ccaccagctg ctccacggat
    24481 ttcaaggatg atattcttgt catcgtttgg atcctttgga aggagcaaaa ttttcagttt
    24541 ttcttcatat tcttcttttt cagccttggc atctttgagt tcttgcttgg ccatttcttc
    24601 caagtccgca tctccgcctg attccttaat catctcttcg gcatcgacga tattttgaag
    24661 gacttgttta tactcacggt aggctattac ggtgtcacga ttggaagctt cttcttttga
    24721 aagctccata aaacgcttgg tgtctgaaac gacatcaggg tcactcagca attctcctag
    24781 ttcttcataa cggtcttcta cagcttgtag ttgatcatag atgttcattt tttctcctta
    24841 tttctcaatt gttaaatcat agattgctac tacttcattc tcggctattt ccccagtttc
    24901 tttaaatcca taactgaggt aacaaaatct tgcctgttca ttttctggtt cataagacaa
    24961 ccaaagttta ttgcttaaac ctgctggcgc tgttcgaaca tagtctagta ctttatccat
    25021 aattggttta aaatatcctt gattttgaaa attcctatca atcataaaac gaaatagtaa
    25081 ataatttcca ctactaattc cgatcttttt atcataagct atcatcacaa aacctataat
    25141 tgcatcatta tcataaactg ccaatgtagc tacaaaatct ccatttttag tgtagacgta
    25201 tgcttcagct aaactaattg cgttggttgc aatgaattgt ttttgatatt ccttgacatc
    25261 caaatttaaa acatcaaaat aattttccat tgtaacatct cttagttcaa ttgtcatagt
    25321 tttgctcctt gttagaggtt atcattggcg taaaataatg tttacggcaa actgagatat
    25381 aggtttcgtt accaccaatc tggatctgtt ctccatcgta aacgggcagt ccatcctgtg
    25441 ttcgcaacac catggtcgcc tttttcttgc aatactgaca gatggtcttg atttcgtcaa
    25501 tcttgtctgc taaaagcaag agatatttgg aaccttcgaa caattcattg cgaaagtcat
    25561 ttttcaagcc aaaagccatg acgggtatgt ctaactcgtc cacaacacga gctaggtcgt
    25621 aaacatggtg gcgtttaaga aactgggctt catcgaccaa aacacagtaa ggtttttctg
    25681 gtaggtctcg gatatagcca aagatatccg ttgtttcctc aatcgcaagg gcagggcgtt
    25741 tcatgccaat tcgactcgac acatagccaa caccgtcacg cgtatccaga gccgaggtca
    25801 taatgacaac accttttcct tgctcctcgt agttataggc cactttgaga atctcaatcg
    25861 ttttaccaga gttcatggtc ccataacgat agtacaactg tgccatgttt cttgcttcac
    25921 gtccatttct aaatttttgc tacattctag tatatcataa ttttcttaag ctttaaacgg
    25981 caaaatgtgg taaaatggaa gaaatcaaaa ctagtggagg aagctattat gccatttgta
    26041 cgcatcgatt tatttgaagg acgcacgctc gagcaaaaga aagctcttgc taaggaagta
    26101 acggaagcag ttgtccgcaa cactggagcc cctcaatctg ctgtccatgt catcatcaac
    26161 gacatgccag aaggaactta cttcccacaa ggggaaatgc gtactaaata agctagctta
    26221 agcagaattg cttaggcttt ttcaatctcc aagtagcatt cattgaagaa atatcctaaa
    26281 tttgttacaa tttgaaaaga aacttggaga atttccaaga aaagagctat taattaaagg
    26341 aaacattatg attacacgtg aatttgatac catcgctgct atctctactc cactaggtga
    26401 aggggctatt ggtattgtcc gcctgagcgg aacagacagt tttgctattg cgcaaaagat
    26461 ttttaaagga aaagacttga acaaggttgc cagccacact ctcaactacg gtcacattat
    26521 tgatcctctg actggtaaag tcatggacga ggttatggtt ggggctatga agtctccaaa
    26581 gaccttcact cgtgaggata ttatcgagat taacacccac ggtgggattg cggtgaccaa
    26641 tgaaattctc cagctagcta ttcgtgaagg ggctcggttg gcagaacctg gtgaatttac
    26701 caaacgtgct tttttaaacg gtcgcgtaga cttgacacag gcagaggctg tgatggatat
    26761 catccgtgcc aagactgaca aggccatgaa cattgcggtc aaacaattag acggctccct
    26821 ttctgacctc attaacaata cccgtcaaga aatcctcaat acacttgccc aagttgaggt
    26881 caatatcgac tatcctgaat atgatgatgt tgaggaagct actactgccg ttgtccgtga
    26941 gaagactatg gagtttgagc aattgctaac caatcttctt agaacagccc gtcgcggcaa
    27001 aatccttcgt gaaggaattt caacagctat catcggacgt cccaacgttg ggaaatccag
    27061 ccttctcaac aacctcttgc gtgaggacaa ggctatcgta acagatatcg ctgggacaac
    27121 acgagatgtc atcgaagagt acgtcaacat caatggtgta cctctcaaat tgattgatac
    27181 agccggtatt cgtgaaacag atgacatagt ggaacaaatc ggtgttgagc gttcgaaaaa
    27241 agccctcaag gaagccgact tggttctact agtgctaaat gccagtgaac cactgactgc
    27301 gcaagacaga caacttcttg aaattagcca agataccaat cgcattattc tacttaataa
    27361 aaccgacctg ccagaaacga ttgaaacttc gaaactacct gaagacgtta tccgtatttc
    27421 agtccttaaa aaccaaaaca tcgacaagat tgaagagcga atcaacaacc tcttctttga
    27481 aaatgctggc ttggtcgagc aagatgctac ttacttgtca aacgcccgtc acatttccct
    27541 gattgaaaaa gcagttgaaa gcctacaagc cgttaatcaa ggtcttgagc tggggatgcc
    27601 agttgatttg cttcaagttg acttgactcg tacttgggaa atcctcggag aaatcactgg
    27661 ggatgctgct ccagatgaac tcatcaccca actctttagc caattctgtt taggaaaata
    27721 agaaaaatcc atgatccttc attcggtcat ggattttatt gtctttatta gtaatctggt
    27781 cttaagaccc ctgttacagt tgccttagtt gcttcgtagt cgccatctac gacaaccttg
    27841 ataatgcgtt tggcatcttc ttctggtgct ggaacaagag gtagacgagt gggtccagct
    27901 tcaaatccca tatagttaag aattgcctta actggagcag gacttggata agagaagaga
    27961 gcattaacct taggaatgaa tttacgctga attgctgcgg ctttcttcat atcgctttct
    28021 gcaatggcag taaacatctc gtgcatttca tccccatttg tatgagaggc aacagaaata
    28081 accccatccg ccccaaggtt catggcatgg aaagcatctc catcctcacc tgtataaatc
    28141 aagaactctt caggcttgtg ctcaatcaag taagccatat tagccaagct agtacattct
    28201 ttgacaccga taatatttgg atggtcagcc aagcgaagca tggtttctgg agtcaattcg
    28261 acaactacac gccctggaat gttatagata ataattggta ggtcagaagc atctgcaata
    28321 gtcttaaagt gctgatacat cccttcttga gaaggtttgt tgtagtaagg aacaatagca
    28381 agcccagctg cgaaaccacc aaattccgct acttctttga caaactcaat agagtcacgc
    28441 gtatcattag tacctacacc cgcaatcaaa ggaacgcgtc cattgacaac cttttgtaca
    28501 gccgcaaaca actccaactc ctcatcgtgg gtcaaagttg gactctcagc agtcgttcct
    28561 gcgagaagaa ttccatccgt atgatgggcc aataaatgct caatcaaggc tggaatagca
    28621 tcaaagttaa tggaaccatc ctcatggaag ggggtaataa aggctgtaat gattttacat
    28681 tcttttaaat cttgataaga cacgaaaaca cctctctatt tcaaagaagg agttcatctg
    28741 aactcctaaa cgatatgact attttaattc aaatttcaat tcggctgttg gacgaaccaa
    28801 tccacgttca tgaagagttt cagcaatctg aactgagttc caagcagcac ctttgagaag
    28861 gttatctgaa acaacccaca tgtgaattcc tttttctgca tccaagtctt tacggatacg
    28921 accaacaaag gtatcacgcg aaccaactgc attgatagct tgaggataga tttgatgagc
    28981 tacatcatct tcaagaacag cacctgggaa ggctgcgata gctgctttta cttcttcgat
    29041 tggagccact tcttttgttt cgatataaac agactcagag tgagctgaca agactggaat
    29101 acgcacacat gttgcagata ctgcaatgct atcatcttcc ataattttct tagtttcctt
    29161 ggtcatcttc atctcttcgt acgtgtaatc attatcagtg aaaacatcaa tttgtggaag
    29221 agcgttaaag gcgataggat aatgtttctt gtcaccacct gaaggcaaga tttccgcatg
    29281 caaatcacgt ggtttcacac catcattcaa aacctcacga agttcacgtt gtgtctcaag
    29341 aattgctccc ataccagcac ctgaaacggc ttgataagtt gaaacaatga tacggtccaa
    29401 gccccatttt tggcgaaccg gctcaagagc caccatcatt tggattgttg aacaattagg
    29461 gcaggcaatg attccgttgt gagcatcaag tgcatgagca ttgacctctg gaacaaccaa
    29521 aggaacatct ggattttgac ggaaataaga tgtattatct actactacca cgccagcttt
    29581 tactgcgtat ggtgcatact tagctgatgt agaactacct gctgaaaaga gagcaatatc
    29641 aactccttca aaagctgttt cagtcgtttc ttcaattgta atatcttgat ctttaaattt
    29701 caatgactta cctgctgaac gtgcagaagc aaggtaacga attttatcga ttggaagtgt
    29761 tgattcttcc aacattttta tcatctgagc accgacagca cctgtcgcgc cgactacagc
    29821 aactgtatat cccataaata acctctttcg gaattttcta aaaatttcta taatagaagt
    29881 attatactac tttttccatg aattgcaaag ctttttcatc attttttgga aaataaaaat
    29941 cccagtcgct agactaggga ctaagaggca tcttcatgtg atgagcaggt tcacacaact
    30001 catcaaggtc cgctcctgcg ttatgacctc cttatgctca atagtagtcc gaagactacc
    30061 tatcgactca tcgcatattc tatattacta gagatacttg attttgtcaa taagaaattt
    30121 tttcgatcga gtataacaaa aaactctcgt attcaagagt ttccctatac atatcatgct
    30181 aattgccggg attgaaccgg cgacctcatc cttaccatgg atgcgctctg ccaactgagc
    30241 taaatcagct tacttaagaa gtatactata ttcagaaaaa cttgtcaagt ttccttagaa
    30301 attttccata ggaaaaagcc aggtaagaac tacctagctt atcttcttct atttacttaa
    30361 atcaattcga cgaccaattt taccaataat aatcgcccca ataatcaatg aagcaaattc
    30421 accgattcct gttgtaaacc aagtaaggaa gaatggtaat tctgctacaa tatttaactc
    30481 tgcagcgata gtaaacatgg aaattgaaaa gaggattgaa aagaagaaat gatcttttcg
    30541 aatcaatccg ttaaagaggt aatccttgct atattttgca aaaagccaaa cacctaaact
    30601 gaggaatact aaggttgaac caccaccaac aaagacatct agcagtccga agctaaagaa
    30661 attagcaatc atacaaccga tggtaactcc gatgatgtac ttaggattgt aaaaagccat
    30721 aaagttcatc atttctgaaa tacgaaactg ataagcacca tagctgatgg catttagggg
    30781 cggtgtgaca gtcaaaacga cgtagatagc agcgacgatt gcaatatctg caacatcacg
    30841 aatagttaat tttttcatct tttctccttt ggcggttgcc cgcgtgtaat atgcttggtg
    30901 aaagaagcta agcaccaagg gttgctttat tcaaccctac tagtatagca caatagcctg
    30961 ctttatgcta tacttaacac atgaaaattc ctattcaaaa attttttaac aatgaaatct
    31021 tagcctatct cttttttggc cttgcgacaa ctctagtttc gattctctca cgactagtca
    31081 tttatcaact aagtcatcag gaactcctgg ctactgccct agcaaatatt atcggtatcc
    31141 tatttgcctt tatcacaaat gatacgattg tatttaagca aaaaaagaaa aatagactta
    31201 tccgtttagt gaaattttct cttgctcgcc tttctacttt tctgttagac ttgtttttaa
    31261 cttttctctt tgtaacccaa tttcctcaca ttatagggca attcgtaact gaaaacattg
    31321 ataagataaa tgctattgaa acaataattg cacaaatatt cattattatc atcaattata
    31381 tcttgagcaa ggcctatatt tttagaaaat aatgctccat ttatgagcct tttaattgcc
    31441 ttctataatg atttaggata caatgaaaca cgaaacattg aaaggaaaac agtatgttaa
    31501 aaaatctaaa atcgttcttg cttcgaggaa atgttattga ccttgctgtc ggtgttgtaa
    31561 ttgcctctgc ttttggtgct atcgttactt cacttgtaaa cgacattatc actcctctta
    31621 ttttaaatcc cgctttgaaa gctgctaaag ttgaacgtat cgctcaactt tcttggcatg
    31681 gagtcggcta tggtaacttc ttaagtgcta ttatcaattt tatctttgtg ggtaccgccc
    31741 tcttctttat tatcaagggc attgaaaaag cacagaaact gactggcata aagaaagaaa
    31801 aaactgccga aaaaaaacca accgaattgg aagtccttca agaaataaaa gctctccttg
    31861 agaaaaaata atcgattaaa aggatctagc gcaaagctaa atcctttttt ctttactctt
    31921 tgggtaactt gcctgctttt tcaagcattt ttttgatcag ataaggcatc ttaacattct
    31981 cccgcccttt tttctcaatc agttttttca caaattctgg catttgtaaa tcttcagatt
    32041 cagctaaaat gtttttcgtc tcgtctgaag gaactaactc atcaaaggtc tcttcttctg
    32101 ggagaaattc cttaaactct tgattttcat tgactctaac tgtattgacc aaagcatcaa
    32161 tcaaacgaga atctgtattt ggcattggtg aacgatggta gtttacccca aattcctggc
    32221 ataagtcata acattctaca tcattgtcaa acaagacctc aatatgctca ctgatgaaac
    32281 taataggtac aaaaatataa tggtctggat gttctgtctg ttctctgaga tactccaaaa
    32341 caaaggatca ccaaagtcca aggcaaaaat gggcacacta tgggctgaaa agatgacttt
    32401 aaaactgtct tgctttactt cttcttttaa aatcttagca atttcatctg cccaatagtt
    32461 taagagcact tcttcctgat accagtcctt aatgaccaaa aattgaattt gtttgctttc
    32521 taaaaatttt tcatagccca tgacagagta gaaagaataa tggggctcca aaatcaagca
    32581 aatacactgt tcaattccgt ctgcttccat ttgaccgatc acatctggaa taaagggact
    32641 ggaaaactta ttagcaaagt agacactgta ttcattcccc agcctagctt ctaccaaggt
    32701 aacctcttga cgggtaattt tttgcagagg cgtgcctcca attcgtacat aattatcata
    32761 gagagtctga atctcgtggt cttggggtct caccccacga cgaatatttg tgaaaaaatc
    32821 agctacacct tcaaaggtaa tctcttctgg tgaaccgaag gtcatcatta aaattgcttt
    32881 tttcatgact gcttccttgt gatgttttta tcaagtttat tttatcatta attcatcgat
    32941 aagtaaacgc taacataggg acattctcaa tcttctgtct tttgtttttc tcttctttct
    33001 atgatacaat ggaaaaaata aattcaaaag gagttttttt atgacttatc caaatctctt
    33061 ggaccgcttc ttaacctacg ttaaggtcaa cacgcgctct gatgaacact ctactactac
    33121 tccaagtaca cagagtcagg ttgacttcgc aacaaatgtc ctaattcctg aaatgaaacg
    33181 tgttggactg caaaatgttt actatctacc gaatggtttt gctattggaa ccttgccagc
    33241 caacgatccg tctttaacac gtaagattgg ttttatatcg cacatggata ctgctgattt
    33301 taatgctgaa ggagtcaatc cacaggtaat tgaaaactac gatggtggtg tgattgaact
    33361 agggaattct ggtttcaaac tcgatccagc tgacttcaag agtcttgaaa aatatccagg
    33421 acaaacgctc atcacaacag atggaacaac cttgctaggt gctgatgaca agtcaggaat
    33481 tgctgaaatt atgacagcca ttgaatatct aactgctcat cctgaaatta agcactgtga
    33541 gattcgtgtt ggttttggtc cagatgaaga aatcggtgtt ggtgccaata aatttgatgc
    33601 agaagatttt gatgtggatt ttgcctacac tgttgatggt ggtccactag gtgaacttca
    33661 gtacgagact ttctcagccg ctggtgctga attgcatttc caaggccgta atgtccaccc
    33721 tggtactgcc aaagggcaga tggtcaatgc ccttcagcta gcaattgatt ttcataatca
    33781 acttccagaa aatgaccgac ctgagttaac tgaaggttac caaggttttt accatctaat
    33841 ggatgtgaca ggtagtgttg aggaggcgcg tgcaagctac atcattcgtg attttgaaaa
    33901 agatgccttt gaagcgcgta aagcatccat gcaatctatc gctgataaga tgaatgcaga
    33961 acttgggagc taccgtgtca ctctcaactt gacagaccag tactacaata tgaaagaagt
    34021 cattgaaaaa gatatgactc caattaccat tgctaaagcc gttatggaag atctaggtat
    34081 cacgcctatt atcgaaccaa tccggggtgg aacagacggc tctaagattt cctttatggg
    34141 aatcccaact ccgaatatct ttgcaggtgg cgaaaatatg cacggacgtt ttgaatacgt
    34201 tagccttcag actatggaac gtgcagttga taccatcatt ggcatcgtag cttataaagg
    34261 ctaaaaagac gaggtagctc agctacttcg cctttctttt tattctactg gtttttcttg
    34321 atttccagta gttgtagaag attctgttgt ttcattttct gaagttgatt cagcaggttt
    34381 agaatctctt gtattgcttg gtttgttttc gtcgctagca atttcaatgt tagattctgc
    34441 agttgcgttt ggttggttct cagcactggt gttatcacta tttgcttcag catttcttgc
    34501 tggacttgtt tcttcacttg cgctagcttt tgactggatt tgatgattca aaactagaat
    34561 agcttttgtc gattcaagta aagctgtttt gtctttactc ttagcagaaa gttgatctaa
    34621 taatgcatcc accttatcaa agtccgcatc agatccatta ttactttcta aataagagtg
    34681 aagcgacatg agaatatcgt agagtttttg atagagtaca agtgtctgag aatcttgctc
    34741 agcattttcc ttttcttgtt gaagggcgct agcgatacga gtcaagacat cttttacctg
    34801 actgtttact tcatccaagt ctgcatcagc cttgtttgtg gcagctttta gattttctac
    34861 ttcttctgcc aaggattgtc tgattccttc ttcatggatt tgttccaaga gttgatttac
    34921 cttgctcaaa agactttcta cttcttcctt gctatctgtc gcagattatt ggttgccatc
    34981 taccatgtac tcctaaaaca ggagagttat aatccaagat tacaaggcct tacagaaata
    35041 agaaatccag ataagacaat gttcgtccaa gacgctattc gcttcgcaca gcagcacgga
    35101 ttcaatatgc tttaatttta aagtttaggt gtcaagacct ctttttagtg tgcccaaaat
    35161 ttagagaagt aatcaatcaa ctaactttta tttttttcaa actttcagta aactgaccta
    35221 aagctaactc aatctgtctt tgtagatgct tctgctatca gctagaagtt gatctacttt
    35281 tgccaagact gccttctcat caaaagttcc aggttgatag ttggattgca gggatggaat
    35341 cttgtttttc aaagccgctt catatccctt agtttgaacc ttgatgtagt gattgtggtc
    35401 gccatgagga atcacaaaac cttctgaatc ttcacttata attcgattgg catcaaaacc
    35461 atgaccatct tcttcctcat gatggacatg tagtgacgga ttacttaata cagaactaga
    35521 agaacttcct acctcttccg tgttagagtg tgatggggga ttgttaagag atgacttagg
    35581 aatatagtga tagtgatccc catgtcttac tatataagca tcacctgtat ctctgacaat
    35641 atcattaggg ttaaagacat atgtggctgc taattcacct gccgacaagt cactctcagg
    35701 aatgaaatga tagtgaccac catgtggtac tatagtagat tgaaatagaa tatgagcaaa
    35761 ttgataaggg gattttaaag taatttctaa caatgattta gaaactatga tgtgctattc
    35821 taaattcaac tcactatata taaccatcat cggtagtata acgtccctgt aattttgcta
    35881 cagatacttc tgcactagct cctttatcgt ctttaccatg ttcttgtttt tggcgattga
    35941 tttcatcttt tgttcgtaca ttttctgcat gagcttgatc tttaaggtaa acataatact
    36001 ttccatctac cttaataata tatcctccct taacctaact gacgatatct tgatctttcg
    36061 gctgatagtt gggggctttc attaatagct cttcactaaa gagcgcatca aaaggaactt
    36121 taccattata gtagtgataa tgatcgccat gagaagttac ataaccttga tctgtaatct
    36181 taataacaat ttgttttgct tgaattcctt ctttttgact aacctagtct ggagtcaaat
    36241 tttcagtctt cttagtgtct ttattactgt ttacatatga aacacgattt ttatctgtat
    36301 tggcctgtta gctatgttgg ttcagagcat aaacacacag acttaaggaa aggataacaa
    36361 cagatccagc tgctatatat ttctttttaa atttcataat tacctcattt ctataattat
    36421 ttatatgatg tcttcattat taaatgatta aataaattaa ttaaccaatt aattaactag
    36481 taaatattcc acctcttttt aagttgtatg tcaagaaatt ttatatatta ataataaaat
    36541 gaaattctcc caaagtcaga gttttatttc taacttttga gagaacttca tttttgattc
    36601 agactttttc tactgctatt ccttacgcta tgagatcaga taaattcttt tttatcactt
    36661 ctccacttgg caatcttaat tcaatcgttc catccatatt gaatataaca ctatctaagc
    36721 ctaatccgta actagctgta aatttttcta atttttcttg tacaggatct actgctggag
    36781 cttcctctaa tgctggatct aacatagggt cactccccac attcccttct ggattcaaca
    36841 ttccattatc cgttgagttt tctggtttta caggtttttc gtttggtgcc tctggtaaag
    36901 aatctgctgg tttattttct gttggttggt tctcaactgt tccagtagat acttttccag
    36961 tttcagatgg tttattttca ccatttcctt gaggtgcttc tcctgtaaaa tctgccatat
    37021 tctttttaat gacttctccc gatggtaaat ataattcaat tgttccgtcc atattaaaca
    37081 agacattttc tagcttcatc ccataacttt cagcaaattt tgctactttt tcttgtacag
    37141 gatccactgt aggaacttct tctaacgttg aatcactagt actgttccca gtttcaggaa
    37201 gcttttcttt ttctaccttc tcactagtct ttggttcttc taccttttca tcaagttttg
    37261 agttttcttg tgctttattc cttttaaatt gtggtagaat acttggttta tcagtttgat
    37321 tttctttttc caagataggt acttccacaa tataagtcga ttgattgtcc aaataagcat
    37381 ttgccatgaa ggttacagga attttatttc cggccgttct ggttgttcct tggtttaatt
    37441 tcggaatcgg taatttaatt tcaccaactt tatagttatt ttctaaataa gcatttccat
    37501 gaaattcatc aaacactctg actaaagcat cagttccttt aggcactgca aattgagggt
    37561 tcactcttaa ataagtatcc cctgcatgga aaggatagaa aatcgtttga ctggccattt
    37621 tgtaagctaa agaggttgga actgtaaatg taccatcata acttacttct ggataatctt
    37681 ttgaagcgat agtatactta aatgtttgtc ctggtaaata aggttgatct aattcaaagt
    37741 ttgcaatatt ccctactcct tctccaaata ctttaccaga tactttctcc aatacttttc
    37801 catctggtgt tattaatttt actagcatat tgatacctaa ttttttttcc aattcaggcg
    37861 gaaaactaaa agaaacgcgt ttttgaccat tggctagagt aaagttttga ttattaaacg
    37921 tactattttt taacaaatta acaacattcg ttaattcttc tccagtataa actttattcc
    37981 cttctttttt agcaactcct tcttcgggtt taaacagttc atagttactg tgagaatgac
    38041 caattccaac cggtttatgt tcatcaatcg gatctgcatg atggtgatct ccatgcggat
    38101 aaataatcgc atttttttct ttattcacga caatactttc acgtttgaca ccatattgtt
    38161 tcataatgcc agcaattttt tcttcgattt ttttatctaa atctttcatt tctttggcat
    38221 tacctggata atcctgttca tgagatgaca aagaatctaa tccattatga ctagttttaa
    38281 cttcctctaa atgtttttgc gcagccttaa tttgctcttc tgtcaagtcc ttcttgaaga
    38341 aataatgatt gtggtctccg tgactcatga caaaacctga ttcatcttca gcgataatac
    38401 gattagcatc aaatccgtat ccatcttctt catgtttctc atgtgaagtt cctggattga
    38461 ttggaagaga tggagaaggt gttgctagac tattgtttgg aagagtcggt tgcccaattt
    38521 gatttgattt tggaatgtaa tggaaatgat caccatgtct tacaatataa gctgtagccg
    38581 tttcttcaac gatatctttt ggattaaaaa tataaccatc agatgctgaa gagagtttct
    38641 tacttgtcgt taaagaagaa ggattgcttg aaagactgcc tagactagac actacttcat
    38701 taggttttgc atttgtagaa actgtagaac cagttccact gataggcacc attctggcaa
    38761 tcttttcttc taaggcagaa agcttgctgt aaggaataaa gtggtaatgg tcgccatgcg
    38821 gaatcgcaac tccatttggt gtacgactga taatcttagc agggtcaaag accaggccat
    38881 ctgattcact gtaacgttgg gcgctaggtg aatcatagag ttccttcaaa agactctgga
    38941 gattttcaga tttatttgct ggcttgctag ttgatccttt tgctacagat tgcgtgttat
    39001 tgtcactagc tgttgaagaa tagcttaact gactcggttg catatttttt ccagccagat
    39061 gtgctttagc tgctgctaat tcactagcag ataaatcgct tttgggaatg tagtgatagt
    39121 gacctccatg aggaacgata taagcattac ccgtatcttc gataatatca gctggattaa
    39181 agacataacc atcatttgtc gtatatcgtc cctgagacct tgctacagca acattagagt
    39241 taaccttctc attatctttg acatgttctt gtttttgacg attgatttca tctttagttc
    39301 gaacattatc agcatgagct gcatctttca ggtagacata atattttcca tcgaccttga
    39361 tgatataacc acccttgact tcattgacaa tatcagcgtc tttaagttga tagtttggat
    39421 ccttcatcaa gagttcttca ctaaagaggg catcataagg aactttccca ttatagtaat
    39481 gatagtggtc accgtgtgac gttacatagc cctgatctgt aattttgatt acaatttgct
    39541 cagcctgaat tccttctttc tggctaacct ggtctggtgt caagttttca cttttctgac
    39601 ttgactggct gccatccaca taagagacac gattattgtc cttattttcc tgcgaacgat
    39661 gctggtttag tgcataggca catagactca aggatacgat aacagctgat ccagctgcta
    39721 tatatttttt actaaatttc ataaatccct catttcaata aatgatgaag tttttttctc
    39781 aacttctttt actttattaa atagttttct aaaccgatta tttaaccatt taattaacca
    39841 gtaaatagtc tactatttaa aattactttt gtcaagtttc tgttacgttt ttctaaaaaa
    39901 gagaagtaac acgaaaggtt acttctccat aaaatatgct ccattcattt tactactgta
    39961 taggagccgg ttgactttct tttaacaaag ccaagagact atctacttct gctgaaatag
    40021 tattattatc tttcgttccg agaagaagac tactttttag accagtcaat gtctccatag
    40081 cattttgtct aatactagaa tctgttactt tttctagcaa ggcctccgcc tctgctatct
    40141 tagcgttaat aacagaatgc tctacttgag gaatttcagc ctcatctgta gtatcttcag
    40201 cttcttcctc tgtctcttcc gtatcagtgc ttggtttata aagattatct gctgaaggat
    40261 ttaaaccagc gtgattctct ttttcatcag attcagggtg agttggctca cttacttcat
    40321 catgttcctt atcttcctca ggtttttctg tctgaggttt ctccgtttga ttggtatcag
    40381 cttgaccatt tttgtttctt tgaacatggt cgctagcgtt accaaaacca ttatctgaat
    40441 gcggacgttc gtttggatgt tcgacatagt acttgacagt cgccaaaaga tcctcaagag
    40501 tatacccctt aggtgcctca taaaggcctt cgtcaaacca ctcaaatttg atgttatggt
    40561 aatggtcata atgaggtatg attaaactac cgtttttgac ttctacagta tattgaagat
    40621 tgta
//
LOCUS       DAVBOG010000014        40457 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.014, whole genome shotgun sequence.
ACCESSION   DAVBOG010000014 DAVBOG010000000
VERSION     DAVBOG010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 40457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40457
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.014"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..69
                     /locus_tag="VQ865_000794"
     tRNA            1..69
                     /locus_tag="VQ865_000794"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:31..33,aa:Gly,seq:tcc)
     gene            104..177
                     /locus_tag="VQ865_000795"
     tRNA            104..177
                     /locus_tag="VQ865_000795"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:138..140,aa:Ile,seq:gat)
     gene            260..349
                     /locus_tag="VQ865_000796"
     tRNA            260..349
                     /locus_tag="VQ865_000796"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:296..298,aa:Ser,seq:tga)
     gene            363..436
                     /locus_tag="VQ865_000797"
     tRNA            363..436
                     /locus_tag="VQ865_000797"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:397..399,aa:Met,seq:cat)
     gene            440..512
                     /locus_tag="VQ865_000798"
     tRNA            440..512
                     /locus_tag="VQ865_000798"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Phe,seq:gaa)
     gene            525..605
                     /locus_tag="VQ865_000799"
     tRNA            525..605
                     /locus_tag="VQ865_000799"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:559..561,aa:Tyr,seq:gta)
     gene            610..680
                     /locus_tag="VQ865_000800"
     tRNA            610..680
                     /locus_tag="VQ865_000800"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:642..644,aa:Trp,seq:cca)
     gene            695..767
                     /locus_tag="VQ865_000801"
     tRNA            695..767
                     /locus_tag="VQ865_000801"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:728..730,aa:His,seq:gtg)
     gene            781..852
                     /locus_tag="VQ865_000802"
     tRNA            781..852
                     /locus_tag="VQ865_000802"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:813..815,aa:Gln,seq:ttg)
     gene            862..945
                     /locus_tag="VQ865_000803"
     tRNA            862..945
                     /locus_tag="VQ865_000803"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:896..898,aa:Leu,seq:caa)
     gene            1052..2329
                     /locus_tag="VQ865_000804"
     CDS             1052..2329
                     /locus_tag="VQ865_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001277926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcysteine synthetase"
                     /protein_id="HET3135174.1"
                     /translation="MSCSIDLLKHRYLKNIKENPELFVGIELEYPVASLEGDATDVEV
                     IKDLFHYLVSTLDLTVAKVDDFGNLIQLVDPISQDAILFEVSYTTIEFAFGKAETIQE
                     VENRFNNYMNVIQRKLAESNHAIVGCGIHPNWDKNENCPVAYPRYQMLMDYLNLSRNI
                     IKSDLHHFPEYGTFICGSQVQLDISKTNYLRVINAFTQIEAAKAYLFANSEFSGADWD
                     TKISRDIFWEESMHGIYPENVGVNARLLNDEADFFDYLNHSAIFTAERDGQTYYFYPI
                     QAGDYLATSEIQAFALNGDEVIIYPQEKDFETHRSYQYQDLTTRGTVEFRSVCTQPLD
                     RTFASAAFHLGLLVNLDKLEAYLETAPFFKVFGYDYKSLRRQFSKKNLTDEEETTIIE
                     FSKDLLLLAEEGLVVRNKEEMTYLQPLREELSL"
     gene            2405..3889
                     /locus_tag="VQ865_000805"
     CDS             2405..3889
                     /locus_tag="VQ865_000805"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006595200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HET3135175.1"
                     /translation="MTLVYQSTRDANNTVTASQAILQGLATDGGLFTPVTYPKVDLDF
                     DKLKDASYQEVAKLVLSAFLDDFTAEELDYCINNAYDSKFDTPAIAPLVKLDGQYNLE
                     LFHGSTIAFKDMALSILPYFMTTAAKKHGLENKIVILTATSGDTGKAAMAGFADVPGT
                     EIIVFYPKGGVSKVQELQMTTQNGDNTHVIAIDGNFDDAQTNVKHMFNDVALREKLTT
                     NKLQFSSANSMNIGRLVPQIVYYVYAYAQLVKTGEIVAGEKVNFTVPTGNFGNILAAF
                     YAKQIGLPVGKLICASNDNNVLTDFFKTRVYDKKREFKVTTSPSMDILVSSNLERLIF
                     HLLGNNAEKTAELMNALNTQGQYKLTDFDAEILDLFAAEYATEEETAAEIKRVYESDS
                     YIEDPHTAVASAVYRKYQAVTGDVTKTVIASTASPYKFPVVAVEAVTGKAGLTDFEAL
                     AQLHEISGVAVPPAVDGLEIAPIRHKTTVAAADMQAAVEAYLGL"
     gene            3950..5230
                     /locus_tag="VQ865_000806"
     CDS             3950..5230
                     /locus_tag="VQ865_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000473957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HET3135176.1"
                     /translation="MFKKNKDILNIALPAMGENFLQMLMGMVDSYLVAHLGLIAISGV
                     SVAGNIITIYQAIFIALGAAISSVISKSIGQKDQSKLAYHVTEALKITLLLSFLLGFL
                     SIFAGKEMIGLLGTERDVAESGGLYLSLVGGSIVLLGLMTSLGALIRATHNPRLPLYV
                     SFLSNALNILFSSLAIFVLDMGIAGVAWGTILSRLVGLVILWSQLKLPYGKLTFGLDK
                     ELLTLALPAAGERLMMRAGDVVIIALVVSFGTEAVAGNAIGEVLTQFNYMPAFGVAMA
                     TVMLLARAVGEDDWKRVASLSKQTFWLSLFLMLPLSFSIYVLGVPLTHLYTTDSLAVE
                     ASVLVTLFSLLGTPMTTGTVIYTAVWQGLGNARLPFYATSIGMWCIRIGTGYLMGIVL
                     GWGLPGIWAGSLLDNGFRWLFLRYRYQRYMSLKG"
     gene            5234..5854
                     /locus_tag="VQ865_000807"
     CDS             5234..5854
                     /locus_tag="VQ865_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3135177.1"
                     /translation="MQKTAFIWDLDGTLLDSYEAILSGIEETFAQFSIPYDKEKVREF
                     IFKYSVQNLLVRVAEDRNLDVEVLNQVRAQSLAEKNAQVVLMPGAREVLAWADESGIQ
                     QFIYTHKGNNAFTILKDLGVESYFTEILTSQSGFVRKPSPEAATYLLDKYQLNSDNTY
                     YIGDRTLDVEFAQNSGIQSINFLESTYEGNHRIQALADISRIFETK"
     gene            6020..7198
                     /locus_tag="VQ865_000808"
     CDS             6020..7198
                     /locus_tag="VQ865_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3135178.1"
                     /translation="MKKRMLLASTVALSFAPVLATQAEEVLWTARSVEQIQNDLTKTD
                     NKTSYTVQYGDTLSTIAEALGVDVTVLANLNKITNMDLIFPETVLTTTVNEAEEVTEV
                     EIQTPQADSSEEVTTATADLTTNQVTVDDQTVQVADLSQPIAEAPKEVASNSEVAETV
                     TAAEEVALSTDSTTPEGQPAETTSPVEEVAPQATTLAEKQETQVSSQTESAVEATTMP
                     VEEKATEATTTSSEAKEVASSNGATAAVSTYQPEETKIISTTYEAPAAPDYAGLAVTK
                     SENAGLQPQTAAFKEEIANLFGITSFSGYRPGDSGDHGKGLAIDFMVPERSELGDKIA
                     EYAIQNMASRGISYIIWKQRFYAPFDSKYGPANTWNPMPDRGSVTENHYDHVHVSMNG
                     "
     gene            7711..8049
                     /locus_tag="VQ865_000809"
     CDS             7711..8049
                     /locus_tag="VQ865_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3135179.1"
                     /translation="MTRYQILLFLLEHSPCNQMAVQERLKIDQAALTRNFKILETEGL
                     VERHRNPENQREVLVEAAKYAKEQLVVNPPLQHIKVKEEMESILTEFERTELSRLLNK
                     LVLGIENIEI"
     gene            8060..8428
                     /locus_tag="VQ865_000810"
     CDS             8060..8428
                     /locus_tag="VQ865_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 domain-containing protein"
                     /protein_id="HET3135180.1"
                     /translation="MSIITIILTTIVALEHFYIFYLESIATQSDATSRVFNMEKEELA
                     HPSVSSLFKNQGIYKALLGVFLLYVIYFSQNLEIVTIFVLFVIGAATYGSLTADKKII
                     LKQGGSAILALISILLFKYT"
     gene            8535..9179
                     /gene="pcp"
                     /locus_tag="VQ865_000811"
     CDS             8535..9179
                     /gene="pcp"
                     /locus_tag="VQ865_000811"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3135181.1"
                     /translation="MKVLVTGFEPFGGEKGNPTLEAIKGLPAEIHGAEVRWLEVPTVF
                     HKSAQVLEEEMNRYQPDFVLCIGQAGGRTSVTPERVAINQDDARISDNEDNQPIDRPI
                     RPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKFPYVK
                     AGFMHIPYMMEQVVNRPTTPTMSLVDIRRGIEAAIGAMIEHGDQELKLVGGETH"
     gene            complement(9207..10064)
                     /locus_tag="VQ865_000812"
     CDS             complement(9207..10064)
                     /locus_tag="VQ865_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HET3135182.1"
                     /translation="MNYPKIDLKTIRQESKHFQADTPRLFLLYILPSMLVILSGFLNP
                     LSRIHGTVLEQPFFSILGQILQTYLFPLLVSFIGTILLTSSVYATLTLMKDSKTEPSV
                     KNSLALFDEERFSQTFLTLLLKRFYLFLWSIPNLLGIYLLFYSSFLAKKFVTLHPEFP
                     NLDLSSVETERFLMVFGLYFLASLILIIVGNILYIPQYYAYSQVEFLLCYSLDLGQVP
                     PRRILKTSRSFMKGYKFQHFVLDLQLLPWYFLNWITFGIASFSLLPYIQCTKIMFYRA
                     VLARKRPKA"
     gene            10194..11336
                     /gene="tgt"
                     /locus_tag="VQ865_000813"
     CDS             10194..11336
                     /gene="tgt"
                     /locus_tag="VQ865_000813"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004298827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HET3135183.1"
                     /translation="MSDSPIKYRLIKKEKHTGARLGEIITPHGTFPTPMFMPVGTQAT
                     VKTQSPEELKEMGSGIILSNTYHLWLRPGDELIARAGGLHKFMNWDQPILTDSGGFQV
                     YSLADSRNITEEGVTFKNHLNGSKMLLSPEKAISIQNNLGSDIMMSFDECPQFYQPYD
                     YVKKSIERTSRWAERGLKAHRRPHDQGLFGIVQGAGFEDLRRQSAHDLVSMDFSGYSI
                     GGLAVGETHEEMNAVLDFTTQLLPENKPRYLMGVGAPDSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAQFAEDFTPLDPECDCYTCNNYTRAYLRHLLKADETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFRKYFVEKYGYNKSGRNF"
     gene            11437..13254
                     /locus_tag="VQ865_000814"
     CDS             11437..13254
                     /locus_tag="VQ865_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HET3135184.1"
                     /translation="MRIKWFSLIRIIGLLLVLLYHFFQTIFPGGFFGVDVFFTFSGFL
                     ITALLIEEFSKNNEIDLIGFFRRRFYRIVPPVVLMVLVTMPFTFLVRQDYVAGIGGQI
                     AGVLGFMTNFYELLTGGSYESQFIPHLFVHNWSLAVEVHYYILWGLAVWFLSKQAKSN
                     GQLKGMIFLLSATAFLISFFSMFIGSFLVTSYSSVYFSSLTHVYPFFLGSMLATIVGV
                     RQTTSLVKQLDKIWDLRKTLVVFGGGFGFLVLLTFFVKFTYLFAYLIGFLLASLAALA
                     MILAARVLHEKTHHIQEPKIISFLADTSYAVYLFHWPFYIIFSQLTSNLLAVLLTLIC
                     SYGFASLSFYVLEPWIAGKNTPILQTLRPLPYIHAILAAGTGILTFIVCMVTLLAPQV
                     GAFETDLTVNGLKQAATNIGQTKVMAERADANSLGIADGTMLIGDSVALRANTALQTA
                     LPGAQINAQVSVTTKTANEIMLNNSQNKFLPKTVVIATGVNNPENYKDDWDSIVKNLP
                     KGHHMILVTPYEGDKTKETYAIVEKAAAYMRELAEKTPYITIADWNQVAKEHPEIWAG
                     TDQVHFGSESSTIEAGAKLYADTIATALQTAQDKPVKSK"
     gene            13407..14558
                     /gene="nagA"
                     /locus_tag="VQ865_000815"
     CDS             13407..14558
                     /gene="nagA"
                     /locus_tag="VQ865_000815"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HET3135185.1"
                     /translation="MPNYIKADQFFYPHGVRRGGYLELVDGKFGKHVEQIPEGAEVID
                     YTGYSIAPGLVDTHIHGYAGVDVMDNNIEGTLHTMSEGLLSTGVTSFLPTTLTATYEQ
                     LLAVTENLGNHYKEATGAKIRGIYYEGPYFTETFKGAQNPTYMRDPGVEEFHSWQKAA
                     NGLLNKIALAPERDGVEDFVRTVTGEGVTVALGHSNATFDEAKKAVDAGASVWVHAYN
                     GMRGLTHRELGMVGAMYQLPHTYAELICDGHHVDPKACEILIKQKGTENIALITDCMT
                     AGGLEDGDYMLGEFPVVVANGTARLKSTGNLAGSILKLKDGLKNVVEWGIANPHEAVM
                     MASFNPAKSVHIDDVCGQIREGYDADFIVLDKDLELVATYLDGVKRYQA"
     gene            14721..15779
                     /locus_tag="VQ865_000816"
     CDS             14721..15779
                     /locus_tag="VQ865_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent alcohol dehydrogenase family
                     protein"
                     /protein_id="HET3135186.1"
                     /translation="MKAYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHI
                     IKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYA
                     HCEDEGGWIFGHLIDGMQAEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGV
                     LKGKVEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVN
                     SSDPKKAIKEIYDLTDGRGVDVAIEAVGIPETFDFCQKIIGVDGTVANCGVHGKPVEF
                     DLDKLWIRNINVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSK
                     AADHHAIKVIIENDISEA"
     gene            15930..16295
                     /locus_tag="VQ865_000817"
     CDS             15930..16295
                     /locus_tag="VQ865_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HET3135187.1"
                     /translation="MYRVIEMYGDFEPWWFLEGWEEDIVASRKFDQYYDALKYYKTCW
                     FRLEQESPLYKSRSDLMTIFWDPEDQRWCDECDEYLQQYHSLALLQDEQVIPDEKLRS
                     GYEKQTSQERNRSCRMKLK"
     gene            16371..17312
                     /locus_tag="VQ865_000818"
     CDS             16371..17312
                     /locus_tag="VQ865_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000249584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II/IV secretion system protein"
                     /protein_id="HET3135188.1"
                     /translation="MVQEIAQEIIRSARKKGTQDIYFVPKLDAYELHMRVGDERCKIG
                     SYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYAYDQKMASLRLSTVGDYRGHESL
                     VIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
                     VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVV
                     RASLTGATVFSTIHAKSIRGVYERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFAN
                     RDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS"
     gene            17260..18276
                     /locus_tag="VQ865_000819"
     CDS             17260..18276
                     /locus_tag="VQ865_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system F family protein"
                     /protein_id="HET3135189.1"
                     /translation="MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLD
                     RSALLDKQCVIQMRVGLSQGKSFSEMMESLGCSSAIVTQLSLAEVHGNLHLSLGKIEE
                     YLDNLAKVKKKLIEVATYPLILLFFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
                     LGMAGLVSVLALLALTFYKRSSKMNVFSILARLPFIGIFVQTYLTAYYAREWGNMISQ
                     GMELTQIFQMMQEQGSQLFKEIGQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGE
                     VKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIVLLYAAMLMPMYQNM
                     EVNF"
     gene            18278..18604
                     /gene="comGC"
                     /locus_tag="VQ865_000820"
     CDS             18278..18604
                     /gene="comGC"
                     /locus_tag="VQ865_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="comG operon protein ComGC"
                     /protein_id="HET3135190.1"
                     /translation="MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKE
                     AVNDKGKAAVVKVVESQAELYSLEKNEDASLSKLKDDGRITEEQVKAYKEYNDKNVGA
                     NRKVND"
     gene            18597..19001
                     /locus_tag="VQ865_000821"
     CDS             18597..19001
                     /locus_tag="VQ865_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HET3135191.1"
                     /translation="MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEF
                     EELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPVPKGIQVPSGQSITFDRAGGNSS
                     LAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN"
     gene            19006..19266
                     /locus_tag="VQ865_000822"
     CDS             19006..19266
                     /locus_tag="VQ865_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000601743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135192.1"
                     /translation="MILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVA
                     KMALQTGQNQVSINGVEIQVFSSEKGLEVYHGSEQLLAIKEP"
     gene            19229..19690
                     /locus_tag="VQ865_000823"
     CDS             19229..19690
                     /locus_tag="VQ865_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000250539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3135193.1"
                     /translation="MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLI
                     SEVRYQQQSEQKEWLLFVDQLEVELDRSQFEKVEGNRLYMKQDGKDIAIGKSKSDDFR
                     KTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES"
     gene            19668..20081
                     /locus_tag="VQ865_000824"
     CDS             19668..20081
                     /locus_tag="VQ865_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGF"
                     /protein_id="HET3135194.1"
                     /translation="MWKKKKVKAGVLLYAVTMAAIFSLLLQFYLNRQVAHYQDYALNK
                     EKLVAFAMAKRTKDKAEQESGEQVFNLGQVSYQNKKTSLVTTVRTSKSQYEFLFPSVK
                     IKEEKRDKKEEVATDSSEKVEKKKSEEKPEKKENS"
     gene            20218..20812
                     /locus_tag="VQ865_000825"
                     /pseudo
     CDS             20218..20812
                     /locus_tag="VQ865_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679792.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
     gene            20873..21826
                     /locus_tag="VQ865_000826"
     CDS             20873..21826
                     /locus_tag="VQ865_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3135195.1"
                     /translation="MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGET
                     ELNQVKDNNQALKHLALRKEEWLKTYQFLLMKAGQTEPLQANHQFTPDAIALLLVFIV
                     EELFKEEEITILEMGSGMGILGATFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
                     AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGL
                     KYLKSDGYAIFLAPSDLLTSPQSNLLKVWLKEEASLVAMISLPENLFANAKQSKTIFI
                     LQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI"
     gene            21877..23067
                     /locus_tag="VQ865_000827"
     CDS             21877..23067
                     /locus_tag="VQ865_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HET3135196.1"
                     /translation="MTKTIAINAGSSSLKWQLYLMPEEKVLAKGLIERIGLKDSISTV
                     KFDGRSEQQILDIENHTQAVKILLDDLIRFDIIKAYDEITGVGHRVVAGGEYFKESTV
                     VEGDVLEKVEELSLLAPLHNPANAAGVRAFKELLPDITSVVVFDTSFHTSMPEKAYRY
                     PLPTKYYTENKVRKYGAHGTSHQFVAGEAAKLLGRPLEDLKLITCHIGNGGSITAVKA
                     GKSVDTSMGFTPLGGIMMGTRTGDIDPAIIPYLMQYTEDFNTPEDISRVLNRESGLLG
                     VSANSSDMRDIEAAVAEGNHEASLAYEMYVDRIQKHIGQYLAVLNGADAIVFTAGVGE
                     NAESFRRDVISGISWFGCDVDDEKNVFGVTGDISTEAAKIRVLVIPTDEELVIARDVE
                     RLKK"
     gene            23216..23587
                     /gene="rnpA"
                     /locus_tag="VQ865_000828"
     CDS             23216..23587
                     /gene="rnpA"
                     /locus_tag="VQ865_000828"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000739244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HET3135197.1"
                     /translation="MKKNFRVKREKDFKAIFKEGTSFANRKFVVYQLENQKNHFRVGL
                     SVSKKLGNAVTRNQIKRRIRHIIQNAKGSLVEDVDFVVIARKGVETLGYAEMEKNLLH
                     VLKLSKIYREGNGSEKETKVD"
     gene            23562..24386
                     /locus_tag="VQ865_000829"
     CDS             23562..24386
                     /locus_tag="VQ865_000829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000727905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HET3135198.1"
                     /translation="MKKKLKLTSLLGLSLLIMTACATNGVTSDITAESADFWSKLVYF
                     FAEIIRFLSFDISIGVGIILFTVLIRTVLLPVFQVQMVASRKMQEAQPRIKALREQYP
                     GRDMESRTKLEQEMRKVFKEMGVRQSDSLWPILIQMPVILALFQALSRVDFLKTGHFL
                     WINLGSVDTTLVLPILAAVFTFLSTWLSNKALSERNGATTAMMYGIPVLIFIFAVYAP
                     GGVALYWTVSNAYQVLQTYFLNNPFKIIAEREAVVQAQKDLENRKRKAKKKAQKTK"
     gene            24405..25391
                     /locus_tag="VQ865_000830"
     CDS             24405..25391
                     /locus_tag="VQ865_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein jag"
                     /protein_id="HET3135199.1"
                     /translation="MVVFTGSTVEEAIQKGLKELDIPRMKAHIKVISREKKGFLGLFG
                     KKPAQVDIEAISETTVVKANQQVVKGVPKKINDLNEPVKTVSEETVDLGHVVDAIKKI
                     EEEGQGISDEVKAEILKHERHASTILEETGHIEILNELQIEEAMREEAGADDLETEQD
                     QTENQDLKEMGLKVEQSYDIAQVATDVTAYVQAIVDDMDVEATLSNDYNRRSINLQID
                     TNEPGRIIGYHGKVLKALQLLAQNYLYNRYSRTFYVTINVNDYVEHRAEVLQTYAQKL
                     ATRVLEEGRSHKTDPMSNSERKIIHRIISRMDGVTSYSEGDEPNRYVVVDTE"
     gene            25442..26065
                     /locus_tag="VQ865_000831"
     CDS             25442..26065
                     /locus_tag="VQ865_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000932659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P"
                     /protein_id="HET3135200.1"
                     /translation="MLNKIRDYLDFAGLQYRNPDKAGAEREKMLAFRHKGQEARKAFT
                     ELAKAFQASHPEWQLQQTSQWMNQAQRLRPHFWVYLQRDGQVTEPMMALRLYGTSTDF
                     GISLEVSFIERKKDEQTLGKQAKVLDIPTVKGIYYLTYSNGQSQRWEANEEKRRTLRE
                     KVRSQEVRKVLVKVDVPMTENSSEEEIVEGLLKSYSKILPYYLATRK"
     gene            26196..27653
                     /locus_tag="VQ865_000832"
     CDS             26196..27653
                     /locus_tag="VQ865_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HET3135201.1"
                     /translation="MEVVSSVLNWFSSNILQNPAFFVGLLVLIGYALLKKPAHDVFSG
                     FVKATVGYMLLNVGAGGLVTTFRPILAALNYKFQIGAAVIDPYFGLAAANNKIAAEFP
                     DFVGTATTALLIGFGINILLVALRKITKVRTLFITGHIMVQQAATVSLMVLFLVPQLR
                     NAYGTAAIGIICGLYWAVSSNMTVEATQRLTGGGGFAIGHQQQFAIWFVDKVAGRFGK
                     KEESLDNLKLPKFLSIFHDTVVASATLMLVFFGAILLILGPDIMSNKEVITSGTLFNP
                     AKQDFFMYIIQTAFTFSVYLFVLMQGVRMFVSELTNAFQGISNKLLPGSFPAVDVAAS
                     YGFGSPNAVLSGFTFGLIGQLITIVLLIVFKNPILIITGFVPVFFDNAAIAVYADKRG
                     GWKAAVILSFISGVLQVALGALCVALLDLASYGGYHGNIDFEFPWLGFGYIFKYLGIV
                     GYVLVCLFLLVIPQLQFAKAKDKEKYYNGEVQEEA"
     gene            27676..27957
                     /locus_tag="VQ865_000833"
     CDS             27676..27957
                     /locus_tag="VQ865_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3135202.1"
                     /translation="MVKVLAACGNGMGSSMVIKMKVENALRKLNQTDFTVNSCSVGEA
                     KGLAVGYDIVIASLHLIQELEGRTNGKLIGLDNLMDDKEITEKLSQALQ"
     gene            28034..28519
                     /locus_tag="VQ865_000834"
     CDS             28034..28519
                     /locus_tag="VQ865_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3135203.1"
                     /translation="MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYY
                     DAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLA
                     LAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLE
                     S"
     gene            28536..29201
                     /locus_tag="VQ865_000835"
     CDS             28536..29201
                     /locus_tag="VQ865_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HET3135204.1"
                     /translation="MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQV
                     GSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALK
                     AIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNK
                     VKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKR
                     IWG"
     gene            29205..30068
                     /locus_tag="VQ865_000836"
     CDS             29205..30068
                     /locus_tag="VQ865_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000252119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HET3135205.1"
                     /translation="MVRPIGIYEKATPTHFTWLERLNFAKELGFDFVEMSIDERDERL
                     ARLDWSKEERLEVVKAIYETGVRIPSICFSGHRRYPLGSKDPVLEEKSLELMKKCIEL
                     AQDLGVRTIQLAGYDVYYEEKSPQTRQRFIKNLRKACDWAEEAQVVLAIEIMDDPFIS
                     SIEKYLAIEKEIDSPFLFVYPDIGNVSAWHNDIYSEFYLGHHAIAALHLKDTYAVTES
                     SKGQFRDVPFGQGCVKWEEAFDILKETNYNGPFLIEMWSENCETVEETRAAVQEAQAF
                     LYPLIKKAGLM"
     gene            30070..30774
                     /locus_tag="VQ865_000837"
     CDS             30070..30774
                     /locus_tag="VQ865_000837"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HET3135206.1"
                     /translation="MNQVINAMRKRVCDANQSLPKHGLVKFTWGNVSEVNRELGVIVI
                     KPSGVDYDELTPENMVVTDLDGKILEGDLRPSSDLPTHVQLYKAWSEIGSVVHTHSTE
                     AVGWAQAGRDIPFYGTTHADYFYGSIPCARSLTKDEVEVAYEKDTGLVIVEEFEHRGL
                     NPVEVPGIVVRNHGPFTWGKNPENAVYHSVVLEEVSKMNRFTEQINPRVGPAPQYILE
                     KHYQRKHGPNAYYGQK"
     gene            30953..32626
                     /locus_tag="VQ865_000838"
     CDS             30953..32626
                     /locus_tag="VQ865_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3135207.1"
                     /translation="MVLDKASCDLLQYLMDQETSKTIMAISKDLKESRRKIYYHIDKI
                     NAALGDEALHIISIPRIGIHLTEEQRDACCKLLSEVDSYDYIMSAHERMMIMLLWIGI
                     SKERITIEKLIELTEVSRNTVLNDLNSIRYQLTLEQYQVILQVSKSQGYHLHAHPLNK
                     IQYLQSLLYHIFMEENATFVSILEDKMKERLDDECLLSVEMNQFFKEQVPLVEQDLGK
                     KINHHEITFMLQVLPYLLLSCHNVEQYQERHQDIEKEFSLIRKRIEYQVSKKLGERLF
                     QKFEISLSGLEVSLVAVLLLSYRKDLDIHAESDDFRQLKLALEEFIWYFESQIRMEIE
                     NKDDLLRNLMIHCKALLFRKTYGIFSKNPLTKQIRSKYGELFLVTRKSAEILEGAWFI
                     RLTDDDIAYLTIHIGGFLKYTPSSQKNMKKVYLVCDEGVAVSRLLLKQCKLYFPNEQI
                     DTVFTTEQFKSVEDIAQVDVVITTNDDLDSRFPILRVNPILEAEDILKMLDYLKHNIF
                     RNKSKSFSENLSSLISSYIVDSKLASKFQEEVQTLINQEIVVQAFLEDI"
     gene            32738..33829
                     /gene="ulaG"
                     /locus_tag="VQ865_000839"
     CDS             32738..33829
                     /gene="ulaG"
                     /locus_tag="VQ865_000839"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HET3135208.1"
                     /translation="MPNVKEITRESWILATFPEWGTWLNEEIEEEVVPEGNFAMWWLG
                     NCGTWIKTPAGANVVMDLWSNRGKSTKKVKDMVRGHQMANMAGVRKLQPNLRVQPMVI
                     DPFAINELDYYLVSHFHSDHIDPYTAAAILNNPKLEHVKFIGPYHCGRIWEGWGVPKE
                     RIIVVKPGDTIELKDMKIHAVESFDRTCLVTLPVNGADETGGELAGLAVTDEEMAQKA
                     VNYIFETPGGTIYHGADSHFSNYFAKHGKDFKIDVALNNYGENPVGIQDKMTSIDLLR
                     MAENLRTKVIIPVHYDIWSNFMASTNEILELWKMRKDRLQYDFHPFIWEVGGKYTYPQ
                     DQHLVEYHHPRGFDDCFEQDSNIQFKALL"
     gene            33943..35919
                     /gene="tkt"
                     /locus_tag="VQ865_000840"
     CDS             33943..35919
                     /gene="tkt"
                     /locus_tag="VQ865_000840"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HET3135209.1"
                     /translation="MSNLSVNAIRFLGIDAINKANSGHPGVVMGAAPMAYSLFTKQLH
                     INPAQPNWINRDRFILSAGHGSMLLYALLHLSGFEDVSMDEIKSFRQWGSKTPGHPEF
                     GHTAGIDATTGPLGQGISTATGFAQAERFLAAKYNREGYNIFDHYTYVICGDGDLMEG
                     VSSEAASYAGLQKLDKLVVLYDSNDINLDGETKDSFTESVRDRYNAYGWHTALVENGT
                     DLEAIHAAIETAKASGKPSLIEVKTVIGYGSPNKQGTNAVHGAPLGADETASTRQALG
                     WDYEPFEIPEQVYADFKEHVADRGASAYQAWTKLVADYKEAHPELAAEVEAIIDGRDP
                     VEVTPADFPALENGFSQATRNSSQDALNVVAAKLPTFLGGSADLAHSNMTYIKTDGLQ
                     DDTNRLNRNIQFGVREFAMGTILNGMALHGGLRVYGGTFFVFSDYVKAAVRLSALQGL
                     PVTYVFTHDSIAVGEDGPTHEPVEHLAGLRAMPNLNVFRPADARETQAAWYLAVTSEK
                     TPTALVLTRQNLTVEDGTDFDKVAKGAYVVYENAADFDTILIATGSEVNLAVSAAKEL
                     ASQGEKIRVVSMPSTDVFDKQDAAYKEEILPNAVRRRVAVEMGASQNWYKYVGLDGAV
                     LGIDTFGASAPAPKVLAEYGFTVENLVKVVRNLK"
     gene            36036..36335
                     /gene="yajC"
                     /locus_tag="VQ865_000841"
     CDS             36036..36335
                     /gene="yajC"
                     /locus_tag="VQ865_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3135210.1"
                     /translation="MNPNITFLIMLVGMMALMFFMQRSQKKQAQKRMESLNKLQKGYE
                     VITIGGLYGTVDEVDTEKGTIVLDVDGVYLTFELAAIKTVLPLKETASLEGAIEK"
     gene            36381..36809
                     /locus_tag="VQ865_000842"
     CDS             36381..36809
                     /locus_tag="VQ865_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000737444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HET3135211.1"
                     /translation="MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNP
                     IHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDK
                     IYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES"
     gene            36811..37221
                     /locus_tag="VQ865_000843"
     CDS             36811..37221
                     /locus_tag="VQ865_000843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000427064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135212.1"
                     /translation="MENLTNFYEKYRVYLTRPRLELLAVVTIVFCAVLVFFLNIPGKG
                     VLKLDNGTIVYDGSLVRGKMNGQGTITFQNGDQYTGGFNNGAFNGKGTFQSKEGWTYE
                     GDFVNGQAEGKGKLTTEQEVVYEGTFKQGVFQQK"
     gene            37520..40171
                     /gene="adhE"
                     /locus_tag="VQ865_000844"
                     /gene_synonym="adhC"
     CDS             37520..40171
                     /gene="adhE"
                     /locus_tag="VQ865_000844"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HET3135213.1"
                     /translation="MADKKTVTPEEKKLVAEKHVDELVQKALVALEEMRKLDQEQVDY
                     IVAKASVAALDAHGELALHAFEETGRGVFEDKATKNLFACEHVVNNMRHTKTVGVIEE
                     DDVTGLTLIAEPVGVVCGITPTTNPTSTAIFKSLISLKTRNPIVFAFHPSAQESSAHA
                     ARIVRDAAIAAGAPENCVQWITQPSMEATSALMNHEGIATILATGGNAMVKAAYSCGK
                     PALGVGAGNVPAYVEKSANIRQAAHDIVMSKSFDNGMVCASEQAVIIDKEIYDEFVAE
                     FKSYHTYFVNKKEKALLEEFCFGVKANSKNCAGAKLNADIVGKPATWIAEQAGFTVPE
                     GTNILAAECKEVGENEPLTREKLSPVIAVLKSESREDGITKARQMVEFNGLGHSAAIH
                     TADEELTKEFGKAVKAIRVICNSPSTFGGIGDVYNAFLPSLTLGCGSYGRNSVGDNVS
                     AINLLNIKKVGRRRNNMQWMKLPSKTYFERDSIQYLQKCRDVERVMIVTDHAMVELGF
                     LDRIIEQLDLRRNKVVYQIFADVEPDPDITTVNRGTEIMRAFKPDTIIALGGGSPMDA
                     AKVMWLFYEQPEVDFRDLVQKFMDIRKRAFKFPLLGKKTKFIAIPTTSGTGSEVTPFA
                     VISDKANNRKYPIADYSLTPTVAIVDPALVLTVPGFVAADTGMDVLTHATEAYVSQMA
                     SDYTDGLALQAIKLVFENLESSVKNADFHSREKMHNASTIAGMAFANAFLGISHSMAH
                     KIGAQFHTIHGRTNAILLPYVIRYNGTRPAKTATWPKYNYYRADEKYQDIARMLGLPA
                     STPEEGVESYAKAVYELGERIGIQMNFRDQGIDEKEWKEHSRELAFLAYEDQCSPANP
                     RLPMVDHMQEIIEDAYYGYKERPGRRK"
BASE COUNT        12275 a         7247 c         9106 g        11829 t
ORIGIN      
        1 gggtgtagtt tagtggtaaa actacagcct tccaagctgt tgtcgcgagt tcgattctcg
       61 tcacccgctt tgaactttgt tctttgtacc aagtttttga cttgggcgcg tagctcaggt
      121 ggttagagcg cacgcctgat aagcgtgagg tcggtggttc gagtccactc gtgcccatag
      181 tgtttagtcc attactaggg gattggaata ttatctgttc actaagagga cacgggcttg
      241 ttcccgtata aactattttg gaggattacc caagtccggc tgaagggaac ggtcttgaaa
      301 accgtcaggc gtgtaaaagc gtgcgtgggt tcgaatccca catcctcctt ttatattatt
      361 aacgcgggat ggagcagctc ggtagctcgt cgggctcata acccgaaggt cgtaggttca
      421 aatcctgctc ccgcaataag gctcggtagc tcagttggta gagcaatgga ttgaagctcc
      481 atgtgtcggc ggttcgattc cgtctcgcgc catttatata ttttggaagg gtagcgaaga
      541 ggctaaacgc ggcggactgt aaatccgctc cttcgggttc gggggttcga atccctcccc
      601 ttccatttta cgggcatagt ttaaaggtag aactaaggtc tccaaaacct tcagtgtggg
      661 ttcaattcct actgcccgtg ttaatagaat tatggcgggt gtggtgaagt ggttaacaca
      721 ccagattgtg gctctggcat gcgtgggttc gatccccatc actcgcctat tttatattat
      781 tggggtatag ccaagcggta aggcaaggga ctttgactcc ctcatgcgtt ggttcgaatc
      841 cagctacccc agttactatt tgccggcgtg gcggaattgg cagacgcgct ggactcaaaa
      901 tccagtgtcc gcaaggacgt gccggttcga ccccggccgc cggtatagta tagtgttagg
      961 aacgttgtta ttcttcgttc cttttttata ttatttttgg tataattata gttattcaaa
     1021 ttttatttag attaagaaag tgtagggtag tatgtcttgt tctatcgatt tattaaaaca
     1081 tcggtatttg aaaaatatta aagaaaatcc tgaattgttt gtcggaattg agttggagta
     1141 tcctgttgca agtttagaag gggatgctac agatgttgaa gttataaagg atctatttca
     1201 ttatttagtt tctactttgg atctcaccgt agcaaaggta gatgattttg gcaatctgat
     1261 ccagttagta gatccgataa gtcaggatgc tattttattt gaagtttcct atacaacgat
     1321 tgagtttgca tttggtaagg ctgaaacgat tcaagaggtc gaaaatcgtt tcaataatta
     1381 tatgaatgta attcagagaa agttagctga atcaaatcat gctattgttg gctgtggtat
     1441 ccatcccaac tgggataaaa atgagaattg tccagtggct tatccacgct atcagatgtt
     1501 gatggattat ttgaatttga gtagaaatat tattaaatca gatttacatc atttccctga
     1561 atatggtact tttatctgtg ggagccaggt tcagctggat atttcaaaaa ccaactactt
     1621 acgggtgatt aatgctttta ctcaaattga agcggctaag gcttatttat ttgcaaactc
     1681 tgaattttcg ggtgcggatt gggatacgaa aatttcaagg gatattttct gggaagaatc
     1741 tatgcatggt atctatccag agaatgttgg ggtcaatgct agactcctta atgatgaagc
     1801 tgattttttt gactatctaa atcattctgc gatttttact gcggaacgtg atgggcagac
     1861 ctattatttt tatcctattc aggctgggga ctatttggct acgtccgaaa tccaagcatt
     1921 tgctctgaat ggggatgagg ttattattta cccccaagag aaggattttg aaactcatcg
     1981 tagttaccag taccaagatt taacgactcg aggaacagtt gagtttcgta gtgtgtgtac
     2041 acagccactt gataggactt ttgcttctgc agcttttcac ttgggattat tggttaattt
     2101 agacaagtta gaagcttact tagaaacagc acctttcttt aaagtatttg gttatgatta
     2161 caagtcttta aggagacaat tttctaagaa aaatcttaca gatgaggaag aaactacgat
     2221 tattgaattt tccaaagact tactcctact agctgaggag ggactagtgg tgagaaataa
     2281 ggaagaaatg acctatttac agcctttgag agaagaattg agcctataat ttctcttata
     2341 aagggagaat tttctgaaaa atcatgatat aatggacgag actatagata aaggatagag
     2401 agtaatgaca ttagtttatc aatcaacgcg tgatgccaac aatacagtaa ctgccagcca
     2461 agcaattttg caaggtttgg cgacggacgg cggtttgttt acaccggtta cttatccaaa
     2521 ggtagatttg gactttgaca aattgaaaga tgcttcttac caggaagttg ctaagctagt
     2581 tttgtcagca tttttagatg actttacagc tgaggagttg gactactgta tcaacaatgc
     2641 ctacgatagc aaatttgata ctccagctat tgcaccatta gtgaaattag atgggcaata
     2701 caatttggaa cttttccatg gttcaacgat tgcctttaag gatatggcct tgtctatttt
     2761 gccatacttt atgacgactg ctgctaagaa acatggtttg gagaacaaga ttgttatctt
     2821 gacagcgaca tctggtgaca cggggaaagc tgctatggcg gggtttgcgg atgtgcctgg
     2881 tactgagatt atcgtctttt atccaaaggg tggtgtcagc aaggtacaag agttgcaaat
     2941 gaccactcag aatggtgaca atactcatgt tattgctatt gatggtaatt ttgacgatgc
     3001 gcaaacaaat gtgaagcaca tgtttaacga cgtggctctt cgtgaaaaat tgactaccaa
     3061 caagttgcaa ttttcatcag ctaactctat gaacattggt cgtctggtgc cacaaattgt
     3121 ttattatgtt tatgcttacg ctcaattggt taagactggt gaaattgtag ctggtgaaaa
     3181 ggttaacttc acagtaccaa caggaaactt tggaaatatc ttggctgcct tttatgccaa
     3241 acaaatcggc ctaccagttg gcaagctaat ctgtgcttca aatgacaata atgtcttgac
     3301 agacttcttt aaaacacgtg tctatgacaa aaaacgtgag tttaaggtaa caaccagccc
     3361 atctatggat atcttggtat cttcaaactt ggagcgcttg attttccatc ttttgggaaa
     3421 taatgctgaa aagacagctg aacttatgaa tgccttgaac acgcaaggac aatataagtt
     3481 gacagacttt gatgcagaga ttttggacct ctttgcagct gaatatgcga ctgaggaaga
     3541 aacagcggca gaaatcaagc gtgtttatga gtcagattct tatattgagg atccacatac
     3601 ggcggttgcc tcagcagttt atagaaaata ccaagcggtt actggagatg taactaagac
     3661 agtgattgct tcaacagcta gtccatacaa gttcccagta gttgcagtag aagctgtaac
     3721 tggaaaagca ggtttgacag actttgaagc cttggctcaa ttacatgaaa tctcaggcgt
     3781 tgcagtgcca ccagcagttg atgggcttga aatagctcca attcgtcaca agacaacagt
     3841 ggcagctgct gacatgcaag cagcggttga ggcttattta ggactttaag acagagggag
     3901 caaactcggt tgggaaacca actgagtttc ttttcatcag gaggagagat tgtttaagaa
     3961 aaataaagac attcttaata ttgcattgcc agctatgggt gaaaactttt tgcagatgct
     4021 aatgggaatg gtggacagtt atttggttgc tcatttagga ttgatagcta tttcaggggt
     4081 ttcagtagct ggtaatatta tcaccattta tcaggcgatt ttcatcgctc tgggagctgc
     4141 tatttccagt gttatttcaa aaagcatagg gcagaaagac cagtcgaagt tggcctatca
     4201 tgtgactgag gcgttgaaga ttaccttact attaagtttc cttttaggat ttttgtccat
     4261 cttcgctggg aaagagatga taggactttt ggggacggag agggatgtag ctgagagtgg
     4321 tggactgtat ctatctttgg taggcggatc gattgttctc ttaggtttaa tgactagttt
     4381 gggagccttg attcgtgcaa cgcataatcc acgtctgcct ctctatgtta gttttttatc
     4441 caatgccttg aatattcttt tttcaagtct agctattttt gttctggata tggggatagc
     4501 tggtgttgct tgggggacaa ttctgtctcg tttggttggt cttgtgattt tgtggtcaca
     4561 attaaaactg ccttatggga agctaacttt tggtttagat aaggaactgt tgaccttggc
     4621 tttaccagca gctggagagc gacttatgat gagagctgga gatgtagtga tcattgcctt
     4681 ggtcgtttct tttgggacgg aggcagttgc tgggaatgca atcggagaag tcttgaccca
     4741 gtttaactat atgcctgcct ttggtgtcgc tatggcaacg gtcatgctgt tggcccgagc
     4801 agttggagag gatgattgga aaagagttgc tagtttgagt aaacaaacct tttggctttc
     4861 tctgttcctc atgttgcccc tgtcctttag tatatatgtc ttgggtgtac cattaactca
     4921 tctctatacg actgattctc tagcggtgga ggctagtgtt ctagtgacac tgttttcact
     4981 acttggtacc cctatgacga caggaacagt catctatacg gcagtctggc agggattagg
     5041 aaatgcacgc ctcccttttt atgcgacaag tataggcatg tggtgtatcc gcattgggac
     5101 aggatatctg atggggattg tgcttggttg gggcttgcct ggtatttggg cagggtctct
     5161 cttggataat ggttttcgct ggttatttct acgctatcgt taccagcgct atatgagctt
     5221 gaaaggatag gaaatgcaaa aaacagcttt tatttgggat ttagacggga ctttattgga
     5281 ctcttacgaa gcgattttat cagggattga ggagactttt gctcagtttt ctattcctta
     5341 tgataaggag aaggtgagag agtttatctt caagtattcg gtgcaaaatt tgcttgtgcg
     5401 ggtggcagaa gatagaaatc tggatgttga ggtgctaaat caggtgcgtg cccagagtct
     5461 ggctgagaag aatgctcagg tagttttgat gccaggtgcg cgtgaggtgc tagcttgggc
     5521 agacgaatca ggaattcagc agtttatata tactcataag gggaacaacg cttttaccat
     5581 tctcaaggac ttgggggtgg aatcctattt tacagagatt ttaaccagtc agagtggctt
     5641 tgtgcggaag ccaagtccag aagcggctac ctatctgcta gataagtatc agttgaattc
     5701 tgataatact tattatatag gggatcggac tctggatgtg gaatttgccc agaatagtgg
     5761 gattcaaagt atcaactttt tagagtctac ttatgaaggg aatcacagga ttcaagcgtt
     5821 agcagatatt tcccgtattt ttgagactaa gtgataaaaa gattgtgtca gttttgtgac
     5881 agagacctaa caaactattt caagtaatct agtttgttac aaggaataga cagttctgtt
     5941 aaataggccc gagagggctt tttttctaca ttttttgtgt tatgatagac aggtactcat
     6001 ttgaaaggaa tttgaaggaa tgaagaaaag aatgttatta gcgtcaacag tagccttgtc
     6061 atttgcccca gtattggcaa ctcaagcaga agaagttctt tggactgcac gtagtgttga
     6121 gcaaatccaa aacgatttga ctaaaacgga caacaaaaca agttataccg tacagtatgg
     6181 tgatactttg agcaccattg cagaagcctt gggtgtagat gtcacagtgc ttgcgaatct
     6241 gaacaaaatc actaatatgg acttgatttt cccagaaact gttttgacaa cgactgtcaa
     6301 tgaagcagaa gaagtaacgg aagttgaaat ccaaacacct caagcagatt ctagtgaaga
     6361 agtgacaact gcgacagcag atttgacaac caatcaagtg accgttgatg atcaaactgt
     6421 tcaagttgca gatctttctc aaccaattgc agaagctcca aaagaagtag catcaaattc
     6481 agaagttgca gagacagtga ctgctgcaga agaagtggca ctatctacag actctactac
     6541 gccagaggga caaccagccg aaacaactag tccagttgaa gaagtagctc ctcaggcaac
     6601 gactctagct gagaagcagg aaacacaagt gagctctcaa accgagtcag cagtggaagc
     6661 aactacaatg ccagtagaag aaaaagcaac cgaagcaact acaacaagtt cagaagcaaa
     6721 agaagtagca tcatcaaatg gagctacagc agcagtttct acttatcaac cagaagagac
     6781 gaaaataatt tcaacaactt acgaggctcc agctgcgccc gattatgctg gacttgcagt
     6841 aacaaaatct gaaaatgcag gtcttcaacc acaaacagct gcctttaaag aagaaattgc
     6901 taacttgttt ggcattacat cctttagtgg ttatcgtcca ggagacagtg gagatcacgg
     6961 aaaaggtttg gctatcgatt ttatggtacc agaacgttca gaattagggg ataagattgc
     7021 ggaatatgct attcaaaata tggccagccg tggcattagt tacatcatct ggaaacaacg
     7081 tttctatgct ccattcgata gcaaatatgg gccagctaac acttggaatc caatgccaga
     7141 ccgtggtagt gtgacagaaa atcactatga ccacgttcac gtttcaatga atggataaac
     7201 ccgacttggt aacatcattt tgacgaatga gatctagctt tcgtgatagg aagcgattct
     7261 cgttcgtttt ttctttgtca tactcttcga aaatctcttc aaacaacgtc agttttatct
     7321 gaaacctcaa agctgtgctt tgagcaacct gcgactagct tcctagtttg ctttttgatt
     7381 ttcattgagt atcaatttga atggaaaatg gaaagttatc atcttgtaat gagttaagca
     7441 acattcttgc aatctatttt atagtagatt gaaactagaa tagtacacaa ctgcttctaa
     7501 aacattgtta gaaatcgatt tgactgtcct gatcgatttg tcctgctctt atttcatttc
     7561 actatacttt atattataat tgactggtca aatattgata aatcaataaa aagagagggg
     7621 aagaaatgct agagattcaa gatttactgt atcaactccg cttgtctgag caagtgagta
     7681 cgcaattgtt tgaaaaagct tgggattagt ttgacacggt atcagatttt actgtttttg
     7741 ctggagcatt ctccttgtaa ccaaatggcg gttcaggagc gtttgaaaat tgatcaggct
     7801 gctttgacac ggaatttcaa gattttggaa acggaaggtt tggtggagcg tcatcgtaat
     7861 cctgaaaatc agcgggaagt attggtagag gctgcgaagt atgccaagga gcagttagtg
     7921 gtgaatcccc ctctgcagca tatcaaggtt aaggaagaga tggaaagtat cttaacagag
     7981 tttgagagaa cagaactcag ccgtttatta aataaattgg ttttgggtat tgaaaatata
     8041 gaaatttaag gagaaataga tgtcaattat tacaattatt ttaacaacga tcgttgcttt
     8101 ggagcatttt tacatttttt atttggaaag tattgccacg caatcagatg cgactagtcg
     8161 tgtatttaat atggaaaagg aagaattggc tcatccgtca gtaagttcat tgttcaaaaa
     8221 tcaagggatt tataaggctc tgctaggagt ctttctcttg tatgtcattt atttctcaca
     8281 gaatttagaa attgtgacta tttttgtctt atttgtgatt ggtgctgcga cttacggctc
     8341 tttaacagcg gataaaaaaa ttattttgaa gcaaggtgga tcagctattt tggccttgat
     8401 tagtatttta ctctttaaat acacttgaag gtcgatttta atctcgctaa tcctttttaa
     8461 tccagaataa gggaaatatg ttatacttgt ttttaagaaa aaagtctcat tgaattggtt
     8521 ttgaggagtt agaaatgaaa gtattagtga caggttttga gccctttgga ggggaaaagg
     8581 gcaatccaac tttggaggcc attaaaggtt taccagctga aatccatggt gctgaggtcc
     8641 gttggctaga ggtgccgaca gtttttcaca aatctgctca agtattggaa gaagagatga
     8701 atcgttatca acctgacttt gtcctttgta ttgggcaagc tggtggaaga actagtgtga
     8761 cacctgaacg agtggccatt aatcaagacg atgcacgcat ttctgataac gaagataatc
     8821 aaccgattga ccgtcccatt cgcccagatg gtgcttcggc ctactttagt agtttgccga
     8881 ttaaagcgat ggttcaagct ataaaaaaag agggcttacc ggcctctgtt tccaatacgg
     8941 cagggacttt tgtctgcagc catttgatgt atcaggctct ctatttggta gaaaagaaat
     9001 ttccatatgt taaggcaggt tttatgcata ttccttatat gatggaacag gtggtgaaca
     9061 gaccgactac tccaactatg agtttagtgg atattcggcg agggatagaa gcagcaatcg
     9121 gcgctatgat agaacatgga gatcaggaac tcaagttggt aggcggagaa actcattgat
     9181 agaaaaaagc ttgaggggaa aaaccttcaa gcttttggac gttttcgagc caatactgct
     9241 cggtaaaaca taattttagt gcattggata taaggtagga gtgaaaaact agcaatgcca
     9301 aaggtaatcc aattgaggaa gtaccaagga agaagctgta aatctaggac aaagtgctgg
     9361 aacttgtagc ccttcataaa ggaacggcta gtttttagga ttcgtcttgg tgggacctgt
     9421 cctaggtcta gactataaca gagaagaaat tccacctgtg aataggcata atactgtgga
     9481 atatagagga tatttcctac aatgatcaag atgagacttg caagaaagta gagtccaaag
     9541 accatgagga aacgctcggt ttcaactgat gagagatcta gatttggaaa ctcaggatgt
     9601 agggtgacga attttttggc taaaaagcta ctataaaaga ggaggtaaat cccaagtaaa
     9661 ttagggatac tccataaaaa gagatagaaa cgtttgagaa gtagggtcaa aaaggtttga
     9721 gaaaagcgct cctcatcaaa gagagctagg ctgtttttta cagatggctc cgttttagaa
     9781 tctttcatga gtgtcagtgt tgcatagacg gaactggtca aaagaatagt cccgataaag
     9841 gagactagta gaggaaagag gtaggtttga agtatttggc caagtatgct gaaaaatggc
     9901 tgttctaaaa cagtcccgtg gatccgagat aagggattaa gaaaaccaga taagatgacc
     9961 agcatactgg gaaggatata gaggagaaag agacgggggg tgtcagcctg aaaatgtttt
    10021 gactcctgac gaattgtttt taaatcaatt tttggatagt tcattctctt attataccat
    10081 agttcttata catagttcgt gacagttcct actttttttg ataaaatcat acagtgtgtc
    10141 cttgggcaca ctgtatgaac tgggactgtc tttcccagct tcggaggtaa aaaatgtcag
    10201 attcaccaat caaatatcgt ttgattaaga aagaaaaaca cacaggagct cgtctaggag
    10261 aaatcatcac tccccacggt acctttccga cacctatgtt tatgccagtt gggacacaag
    10321 ccactgtcaa aactcagtca cctgaagaat tgaaggagat gggttcggga attatcctat
    10381 caaacaccta tcatctctgg cttcgccctg gagatgaact cattgcacgc gctggtggtc
    10441 tccacaagtt catgaattgg gaccagccta tcttgacaga tagtggtggt tttcaggttt
    10501 attctttagc agatagccgt aatatcacag aagaaggagt aacctttaaa aatcatctaa
    10561 atggttctaa gatgctccta tccccagaaa aagccatctc tattcagaat aatctgggtt
    10621 cagacatcat gatgtccttt gatgaatgtc ctcagtttta tcaaccttat gactacgtta
    10681 agaaatcgat cgagcgtacc agccgttggg ctgagcgtgg tttgaaggct caccgtcgtc
    10741 cacatgacca aggtttgttt ggaattgtgc aaggtgcagg atttgaagac cttcgccgcc
    10801 aatcagctca cgatcttgtc agcatggatt tctcaggcta ctctatcggt ggtttggcag
    10861 tgggagaaac ccatgaagag atgaatgcgg tcttggactt tacaactcaa ctgctgcctg
    10921 aaaataaacc tcgttatctg atgggtgtgg gagcgccaga tagcttgatc gatggggtca
    10981 ttcgtggggt ggatatgttt gactgtgtct taccgactcg aattgctcgt aacgggactt
    11041 gtatgaccag tcaaggacgt ttggttgtga aaaatgccca gtttgctgag gactttacgc
    11101 cactggatcc tgagtgtgat tgctacacat gtaataacta tacacgcgct taccttcgtc
    11161 acctgctcaa ggctgatgaa acctttggta tccgcttgac tagctaccac aatctttact
    11221 tcttgcttaa cctgatgaag caagtgcgac aagccatcat ggatgacaat ctcttggaat
    11281 tccgtaagta ttttgtggaa aaatatggct ataataagtc aggacgtaat ttctaaaatg
    11341 gaattgatat aagctaaaaa tcctaagttt tctcttagga tttttcttct ttttttgata
    11401 gaataaagtg tacaatgaaa ggaagaataa actcgtatgc gcattaaatg gttttccttg
    11461 attaggatta taggtttact tttggtactc ttgtatcact tctttcagac gatctttcct
    11521 ggaggatttt tcggggtaga tgtctttttc acattttcag gtttcctgat tacagctcta
    11581 ctcattgaag aattttctaa gaacaatgag attgatttga taggattttt tagaagacgc
    11641 ttttatcgga ttgtgccacc tgtggttttg atggtcttgg tgaccatgcc ttttactttc
    11701 ttggttcgcc aagactatgt tgctggaatt ggtggccaga ttgcgggcgt cttaggcttt
    11761 atgaccaact tctatgaact cttaacaggt gggagttatg aatctcagtt cattcctcat
    11821 ttgtttgttc ataattggag tttggcagtt gaggttcact actatattct ttggggattg
    11881 gcagtttggt tcttatccaa acaagctaaa tcaaatggtc agttgaaggg gatgatcttt
    11941 ctcttatctg ctactgcctt cttgatcagt ttcttctcca tgtttattgg tagttttcta
    12001 gtgacctctt attcctctgt ttatttctcc agtttaactc atgtctatcc attctttttg
    12061 ggaagtatgt tagcaactat tgtaggcgtt cgtcagacga cttccctcgt caagcagttg
    12121 gataaaatct gggatttacg aaagacttta gtagtttttg gaggaggctt tggtttccta
    12181 gttcttttga ctttctttgt caaattcact tatctttttg cctatcttat cggcttcttg
    12241 cttgccagtc ttgcagctct tgccatgatt ctggcggcgc gtgtcttaca tgaaaagaca
    12301 catcatatac aggagccgaa gattatcagc tttttagcgg atactagcta tgcggtttat
    12361 cttttccatt ggcctttcta tatcattttc tcacagttga catcaaatct tcttgctgta
    12421 ttactgactc tgatttgttc ttatggcttt gccagtctgt cattttatgt attggaacct
    12481 tggattgcag gcaagaacac acctatttta caaactcttc gtcccctgcc ttatattcac
    12541 gcaattcttg cagcaggtac aggaatcttg accttcattg tctgcatggt gaccttgttg
    12601 gcaccacaag tgggagcgtt tgagacagac ttgactgtca atggcttgaa gcaagctgca
    12661 acaaatattg gccagaccaa ggtgatggca gaacgggcag atgcaaacag tttgggaatt
    12721 gctgatggca ctatgttaat tggtgactca gtggctttaa gggcaaatac agcactacag
    12781 acagctcttc ctggagcaca gattaacgcg caggtcagcg taacaaccaa gaccgcaaat
    12841 gaaatcatgc taaataatag ccagaataaa tttttaccta agacggtggt cattgcgact
    12901 ggggtaaata atcctgagaa ttacaaggat gactgggaca gtatcgtgaa aaatcttcct
    12961 aagggacacc atatgatttt ggtgactcct tatgagggtg ataagacaaa agagacctat
    13021 gccatcgttg agaaggctgc tgcctatatg agagaattgg cagagaagac accttacatt
    13081 acgatagcag attggaatca agttgcgaaa gagcatccag aaatttgggc tggaacagac
    13141 caggttcatt tcgggagtga gagtagcact atcgaagcag gagcaaaatt gtatgcagat
    13201 acgattgcca cagctttgca gacagctcaa gacaagccgg ttaaatcaaa ataacttgta
    13261 ttaaaaaaga gaagagttgg agaaatccag ctcttttaaa atatctccaa aaaataggtc
    13321 tataccattt acaaataaaa aagaaaggtt tataatgtaa ttgacataat aaattgtaga
    13381 atcaatcttt taaggaggtt aacattatgc ctaactatat taaagcggat cagtttttct
    13441 acccacacgg agttcgtcga ggtggttact tggaacttgt ggacggcaag tttggaaaac
    13501 atgtagagca gattcctgaa ggggctgagg tgattgacta tacaggttat agcattgccc
    13561 caggtcttgt ggatactcat attcatggat atgcaggtgt agatgtgatg gacaacaaca
    13621 ttgaaggtac attgcatact atgagtgaag gacttcttag taccggtgtt accagtttct
    13681 tacccacaac tttaacagcc acttatgagc aattgcttgc agtcactgaa aatcttggaa
    13741 accattataa agaagcaaca ggtgctaaga ttcgtgggat ttattatgaa ggtccatatt
    13801 tcacagaaac ttttaagggg gcacaaaatc caacttatat gagagacccg ggtgttgagg
    13861 agtttcattc ttggcaaaaa gcggcaaatg gcttgcttaa taaaattgcc cttgcaccag
    13921 aacgtgatgg ggtggaagac tttgttcgta cagttacggg cgaaggtgtg acggttgctc
    13981 ttggacattc aaacgcgact tttgatgaag ccaaaaaagc agtcgatgct ggagcgagtg
    14041 tttgggtgca tgcctacaat ggaatgcgtg ggttgactca ccgtgaattg ggtatggttg
    14101 gagccatgta ccaattgcca catacctatg cagagttgat ctgtgatggt caccacgtag
    14161 atccaaaggc ttgcgaaatt cttatcaaac aaaaaggaac agaaaacatc gctcttatca
    14221 cagactgtat gacagctggg ggattggaag acggagatta tatgttggga gaattcccag
    14281 ttgtcgttgc aaatggaact gcacgcctca aatcgacagg taacttggca ggttctatcc
    14341 tcaaactcaa agatggtttg aagaatgtgg tcgaatgggg aattgcgaat ccgcatgaag
    14401 cagtcatgat ggccagcttc aacccagcta aatccgttca catcgatgac gtctgtggcc
    14461 aaatccgtga aggctacgac gctgacttca tcgtattaga taaagatttg gaattggtag
    14521 caacctacct agatggcgtg aaacgttatc aagcataaga gagaaggcag aagttagaga
    14581 ctaacttctg cttttttata cagggtactt tactggtaaa taaaaagtta aaaaaatcac
    14641 aaaaaaagct tgaagaaaca aagaaaaatg cttacaattg aactataaat attacaaata
    14701 aaaaaacgga ggagtgcttt atgaaagcct atacttatgt taaaccagga cttgcttctt
    14761 ttgttgatgt agacaaacca gttattcgca agccaacaga cgctattgtg cgtattgtaa
    14821 aaaccactat ttgtggaaca gacctccata ttatcaaagg ggatgttcct acttgccaaa
    14881 gtggtaccat tcttggccac gaagggattg ggattgttga agaagttggg gaaggagttt
    14941 ccaacttcaa aaaaggtgac aaggtcttga tttcttgcgt ctgtgcctgt ggtaaatgct
    15001 actactgtaa aaaaggaatt tatgcccact gtgaagacga agggggctgg attttcggtc
    15061 acttgattga tggtatgcag gctgaatatc tacgtgtccc tcatgcagat aatactcttt
    15121 accatactcc agaagacttg tcagatgaag ctttggttat gctgtcagac attctgccta
    15181 ctggatatga aattggtgtc ttaaaaggga aagtagaacc tggttgcagc gtagccatta
    15241 ttggttcagg tccagttgga ttggctgctc ttttaacagc ccaattctat tcaccagcta
    15301 aattgattat ggtagaccta gacgataacc gcttggaaac tgccctatca ttcggtgcga
    15361 ctcataaggt taattcttca gaccctaaaa aagccattaa agaaatttat gatttgacag
    15421 atggtcgtgg tgtggatgtc gctatcgaag ctgtagggat tcctgaaaca tttgatttct
    15481 gtcaaaagat tatcggtgta gacggaacgg ttgccaactg tggtgtgcat ggtaaaccag
    15541 ttgaattcga tttagataaa ctttggattc gcaacatcaa tgtaacaact ggtttggtat
    15601 ctacaaatac gactccacaa ttgttgaaag cacttgaaag tcataagatt gaaccggaaa
    15661 aattggtaac tcactatttc aaactcagtg aaattgaaaa agcctacgaa gtcttcagta
    15721 aggcagcaga ccaccatgcc attaaggtca ttatcgaaaa cgatatctca gaagcctaag
    15781 tagtaaaaat atttttgtac ataagcaaat agaaattcag tcatccatca gatggctgga
    15841 ttttttatca aaaaattaag aaatgagcat atttctttcc ttgtctggcg gaattggtta
    15901 taatatacgg tacaaaggaa tgaatgaata tgtatcgtgt tatagaaatg tacggagatt
    15961 ttgaaccgtg gtggttctta gaaggttggg aagaagatat tgtagcaagt agaaaatttg
    16021 accagtatta tgatgctctc aaatactaca aaacttgctg gtttagattg gaacaagaat
    16081 cccctcttta taaaagtaga agcgacttga tgaccatttt ttgggacccg gaagaccaac
    16141 gctggtgtga tgaatgtgat gagtatttac aacaatacca ttctttggct cttttgcagg
    16201 atgagcaggt tatcccagac gaaaaactac gctcaggcta tgaaaaacaa accagtcagg
    16261 aaaggaatcg ttcttgccgt atgaaattaa aatagagaaa agtaactttt ttggagttgc
    16321 tttttttatt tttctaacgc tttgcgaata gtataggtga ggaggtaagt atggttcaag
    16381 aaattgcaca agaaatcatt cgttcagctc ggaaaaaagg gacgcaggat atttattttg
    16441 tccctaagtt agacgcctat gagcttcata tgagggtagg agacgagcgc tgtaaaattg
    16501 gtagctatga ttttgaaaag tttgcagccg ttatcagtca ctttaagttt gtggcgggta
    16561 tgaatgtggg agaaaaaaga cgtagtcaac tgggttcctg tgattatgcc tatgaccaga
    16621 agatggcgtc tctacgttta tctactgtag gcgattatcg gggacatgag agtttggtta
    16681 tccgtttgtt gcacgatgag gagcaggact tgcatttttg gtttcaggat attgaagaat
    16741 taggcaagca gtacaggcaa cggggactct atctttttgc tggcccggtt gggagtggta
    16801 agacgacctt gatgcatgaa ttgtccaagt cactctttaa aggacagcaa gttatgtcca
    16861 tcgaagatcc tgtcgaaatc aagcaggacg acatgcttca gttgcagttg aacgaagcaa
    16921 tcggcctaac ctatgaaaat ctaatcaaac tttccttgcg tcatcgacca gatctcttga
    16981 ttatcggaga aattcgtgac agcgagacgg cgcgtgcagt ggtcagagct agtttgacag
    17041 gtgcgacagt cttttcaacc attcacgcca agagtatccg aggtgtttat gagcgtctgc
    17101 tggagttggg tgtgagtgaa gaagaattgg cagttgttct gcaaggagtc tgctaccaga
    17161 gattaatcgg gggaggagga atcgttgact ttgcaaacag agattatcaa gaacaccaag
    17221 cagccaagtg gaatgagcaa attgaccagc ttcttaaaga tggacatatc acaagtcttc
    17281 aggctgagac ggaaaaaatt agctacagct aagcaaaaaa atatcatcac cctatttaac
    17341 aatctctttt ctagcggttt tcatctggtg gagactatct cctttttaga taggagtgct
    17401 ttgttggaca agcagtgtgt gatccagatg cgtgtgggct tgtctcaggg gaaatcattc
    17461 tcagaaatga tggaaagttt gggatgttca agtgctattg tcactcagtt atccctagct
    17521 gaagttcatg gcaatctcca cctgagtttg ggaaagatag aagaatatct ggacaatctg
    17581 gccaaggtca agaaaaaatt gattgaagta gcgacctatc ccttgatttt gctgtttttt
    17641 cttctcttaa tcatgctggg gctacggaat tacctgctcc cacaactgga tagtagcaat
    17701 attgccaccc gaattatcgg taatctgccc caaatttttc taggcatggc agggcttgtt
    17761 tccgtgcttg cccttttagc actaactttt tataaaagaa gttctaagat gaatgtcttt
    17821 tctatcttag cacgccttcc ctttattgga atctttgtgc agacctattt gacagcctat
    17881 tatgcacgtg aatgggggaa tatgatttca cagggaatgg agttgacgca gatttttcaa
    17941 atgatgcagg aacaaggttc ccagctcttt aaagaaatcg gtcaagatct ggctcaaacc
    18001 ctgaaaaatg gccgtgaatt ttctcagacg ataggaacct atcctttctt taggaaggaa
    18061 ttgagtctca tcatagagta tggggaagtt aagtccaagc tgggtagtga gttggaaatc
    18121 tatgctgaaa aaacttggga agcctttttt acccgagtca accgcaccat gaatttggtg
    18181 cagccactgg tttttatctt tgtggcactg attatcgttt tactttatgc ggcaatgctc
    18241 atgcccatgt atcaaaatat ggaggtaaat ttttaaaatg aaaaaaatga tgacattctt
    18301 gaaaaaagct aaggttaaag cttttacatt ggtggagatg ttggtggtct tgctgattat
    18361 cagcgtgctt ttcttgctct ttgtacctaa tctgaccaag caaaaagaag cagtcaatga
    18421 caaaggaaaa gcagctgttg ttaaggtggt ggaaagccag gcagaacttt atagcttgga
    18481 aaagaatgaa gatgctagcc taagcaagtt aaaagacgat gggcgaatca cggaagaaca
    18541 ggttaaagct tataaagaat acaatgataa aaatgtagga gcaaatcgta aagtcaatga
    18601 ttaaggcctt taccatgctg gaaagtctct tggttttggg tcttgtgagt atccttgcct
    18661 tgggcttgtc cggctctgtt cagtccactt ttgcggcagt agaggaacag attttcttta
    18721 tggaatttga agaactctat cgggaaaccc aaaaacgcag tgtagccagt cagcaaaaga
    18781 ctagtctgaa cttagatggg cagacgatta gcaatggcag tcaaaagttg ccagtcccta
    18841 aaggaattca ggtcccatca ggccaaagta ttacatttga ccgtgctggg ggcaattcgt
    18901 ccctggctaa ggttgaattt cagaccagta aaggagcgat tcgctatcaa ttatatctag
    18961 gaaatggaaa aattaaacgc attaaggaaa caaaaaatta gggcagtgat tttactggaa
    19021 gcagtagtcg ctctagctat ctttgccagc attgcgaccc tccttttggg acaaattcaa
    19081 aaaaataggc aagaggaagc aaaaatcttg caaaaggaag aagtcttgag ggtagctaag
    19141 atggccttgc agacggggca aaatcaggta agcatcaacg gagttgagat tcaggtattt
    19201 tctagtgaaa aaggattgga ggtctaccat ggttcagaac agttgttggc aatcaaagag
    19261 ccataaggtc aaggctttta ccttgttaga atccctgctt gccctcattg tcatcagtgg
    19321 gggattactc ctttttcaag ctatgagtca gctcctcatt tcagaagttc gctaccagca
    19381 acaaagcgag caaaaggagt ggctcttgtt tgtggaccaa cttgaggtag aattagaccg
    19441 ttcgcagttc gaaaaagtag aaggcaatcg cctatacatg aagcaagatg gcaaggacat
    19501 cgccatcggt aagtcaaagt cagacgattt tcgtaaaacc gatgctagtg gacgggggta
    19561 tcagcctatg gtttatggcc tcaaatcagc tcagattaca gaggacaatc aactggttca
    19621 ttttcgtttc cagtttcaaa aaggcttaga aagggagttc atctatcgtg tggaaaaaga
    19681 agaaagttaa ggcaggtgtt ctcctctatg cagtcaccat ggcagctatc tttagtcttt
    19741 tgttgcaatt ttacttgaac cgacaagtcg cccactatca agactatgct ttgaataaag
    19801 aaaaattggt tgcttttgcc atggctaaac gaaccaagga taaagccgag caagaaagtg
    19861 gggaacaggt ctttaatcta ggtcaggtaa gctatcaaaa caagaaaaca agcttggtga
    19921 cgactgttcg tacgtctaag agccaatatg agtttctgtt tccttcagtc aaaatcaaag
    19981 aagagaaaag agataaaaag gaagaggtag cgaccgattc aagcgaaaaa gtggagaaga
    20041 aaaaatcaga agagaagcct gaaaagaaag agaattccta gtcaattcaa ctataatgcg
    20101 ttgaatcaag aatagtccac tatagtttct agaaaattgc tggaaatgga tgttaagctc
    20161 caattcattt gtttatatct tatttcagtt tactatactt tgtgctaaat taaagatatg
    20221 aaacatgatt ttaaccacaa agcagaaact ttcgattccc ctaaaaatat cttcctcgca
    20281 aacttggtat gtcaagcagc cgagaaacag attgatcttc tatcagacaa agaaatttta
    20341 gatttcggtg gtgacacggg tctattagcc ttgcccctag cccctagcca agcaggctaa
    20401 gtcagtcact cttgtagaca tttctgagaa aatgttggag caagctcgtt tgaaagtgga
    20461 gcagcaagca atcaagaata tccagttttt ggagcaagat ttaccgaaaa atcccttgga
    20521 gaaagagttt gattgccttg ctgttagtcg ggttcttcat catatgcctg atttggatgc
    20581 ggctctctca ctgtttcatc aacatttgaa gtaagatggg aaactcatca ttgctgattt
    20641 taccaagaca gaagctaatc atcatggatt tgatttagct gaactggaaa acaagctaat
    20701 tgagcatggt ttttcatctg tgcatagtca gattctctat agcgctgaag acttgtttca
    20761 aggaaatcac tcagaattct ttttaatagt agcccaaaaa tcactcgcct agtcagggag
    20821 tgatttttct ataaggatgg aaaaaagaag ggaaatttga taagatagga atatggattt
    20881 tgaaaaaatt gaacaagctt atacctattt actagagaat gtccaagtca tccaaagtga
    20941 tttggcgacc aacttttatg acgccttggt ggagcaaaac agcatctatc tggatggtga
    21001 aactgagcta aaccaggtca aagacaacaa tcaggccctt aagcatttag cactacgcaa
    21061 agaagaatgg ctcaagacct accagtttct cttgatgaag gctgggcaaa cagaaccctt
    21121 gcaggccaat caccagttta caccggatgc tattgcttta cttttggtgt ttattgtgga
    21181 agagctgttt aaagaggagg aaattactat cctcgaaatg ggttctggga tgggaatttt
    21241 gggcgctact ttcttgacct cgcttactaa aaaggtggat tatttgggaa tggaagtgga
    21301 tgatttgctg attgatttgg cagctagcat ggcagatgta attggtttgc aggctggctt
    21361 tgtccaagga gatgccgttc gtccacaaat gctcaaagaa agtgatgtgg tcatcagcga
    21421 cttgcctgtt ggctattatc ctgatgatgc cgttgcgtcg cgccatcaag ttgcttctag
    21481 tcaagaacat acttacgccc atcacttgct catggaacaa ggacttaagt acctcaagtc
    21541 agacggatac gctatttttc tagctccgag tgatttgttg accagtcctc aaagtaattt
    21601 gttgaaagtc tggttgaaag aggaggcaag tctggttgct atgattagtt tacctgaaaa
    21661 tctctttgct aatgctaaac aatctaagac tatttttatc ctacagaaga aaagtgaaat
    21721 agcagtagag ccttttgttt atccacttgc tagcttgcaa gatgcaagtg ttttaatgaa
    21781 atttaaagaa aattttcaaa aatggactca aggtactgaa atataaaata gattttgtta
    21841 taatagttga aaacgcttaa aaaggggtat catgttatga caaaaacaat tgcaatcaat
    21901 gcaggaagtt caagtttgaa atggcaatta tacttaatgc cagaagaaaa agtattggcg
    21961 aaaggtttga ttgaacgtat cggtttgaaa gattcaattt caactgtaaa atttgacggc
    22021 cgttctgaac aacaaatttt ggatattgaa aatcatacac aagctgttaa aattttattg
    22081 gatgacttga ttcgtttcga tattatcaag gcttatgacg agattacagg tgttggacat
    22141 cgtgttgttg ctggtggaga atatttcaaa gaatcaacag ttgttgaggg agatgtttta
    22201 gaaaaagttg aagagttgag tttgttggct cctctacaca acccggcaaa tgcagcaggt
    22261 gttcgtgcct tcaaggaatt gttgccagac attaccagtg tagttgtttt tgatacttcc
    22321 ttccacacaa gtatgccaga gaaagcttat cgctaccctc taccaacaaa atattacaca
    22381 gaaaacaagg ttcgtaaata cggtgctcat ggtacaagtc accagtttgt agcaggagaa
    22441 gctgcaaaac tcttgggacg tccattagaa gacttgaagt taattacctg tcatattggt
    22501 aacggaggct caattacagc tgtgaaagcc ggcaaatctg tagacacttc tatggggttc
    22561 actcctcttg gtggtattat gatgggaacg cgtacagggg atattgatcc agctatcatt
    22621 ccttatttaa tgcaatatac agaggatttt aacacaccag aagatatcag tcgtgttctt
    22681 aaccgtgaat caggtctttt gggagtttct gctaattcta gcgatatgcg cgatatagaa
    22741 gcagctgtag cagaagggaa tcacgaggct agcttggctt atgaaatgta tgttgaccgt
    22801 atccaaaaac atatcggtca gtaccttgca gtgctaaatg gagcagatgc cattgttttc
    22861 acagcaggtg tcggtgaaaa tgcagagagt ttccgtcgtg atgtaatctc agggatttcg
    22921 tggtttggtt gtgatgttga tgatgaaaag aatgtctttg gcgttacagg agacatctca
    22981 acagaggcag ctaaaatccg tgtcttggtt attccaacag atgaagaatt agtcattgcc
    23041 cgtgacgttg aacgcttgaa aaaataagtg aaactaaaaa aatattcaat acaaggagtt
    23101 gggaaagtta tttttccagc ttctttttct gatgaaattg tccaaaacct tgctatgatt
    23161 ggcttttttg aaaaatatgg tataatagta gtaatttaat agatggagtt gagttttgaa
    23221 gaaaaacttt cgtgtaaaaa gagagaaaga ttttaaggcg attttcaagg aggggacaag
    23281 ttttgctaat cgcaaatttg tggtctacca attagaaaac cagaaaaacc attttcgagt
    23341 aggtctatca gttagcaaaa aactggggaa tgccgtcact agaaatcaaa ttaagcgacg
    23401 gattcggcat attatccaga atgcaaaagg gagtctggta gaagatgtcg actttgttgt
    23461 cattgctcga aaaggagtcg aaaccttggg atacgcagag atggagaaaa atctactcca
    23521 tgtattaaaa ttatcaaaga tttaccggga aggaaatggg agtgaaaaag aaactaaagt
    23581 tgactagttt gctaggactg tctctgttaa tcatgacagc ctgtgcgact aatggggtaa
    23641 ctagcgatat tacagccgaa tcggctgatt tttggagtaa attggtttac ttctttgcgg
    23701 aaatcattcg ctttttatcg tttgatatta gtatcggagt ggggattatt ctctttacgg
    23761 tcttgattcg tacagtcctc ttgccagtct ttcaggtgca aatggtggct tctaggaaaa
    23821 tgcaggaagc tcagccacgc attaaggcgc ttcgagaaca atatccaggt cgagatatgg
    23881 aaagcagaac caaactagag caggaaatgc gtaaagtatt taaagaaatg ggtgtcagac
    23941 agtcagactc tctttggccg attttgattc agatgccggt tattttggcc ctgttccaag
    24001 ccctatcaag agttgacttt ttaaagacag gtcatttctt atggattaac cttggtagtg
    24061 tggatacaac ccttgttctt ccgattttag cagcagtatt caccttttta agtacttggt
    24121 tgtccaacaa agctttgtct gagcgaaatg gcgctacgac tgcgatgatg tatgggattc
    24181 cagtcttgat ttttatcttt gcagtttatg cgccaggtgg agtcgcccta tactggacag
    24241 tgtctaatgc ttatcaagtc ttgcaaacct atttcttgaa taatccattc aagattatcg
    24301 cagagcgcga ggccgtagta caggcacaaa aagatttgga aaatagaaaa agaaaagcca
    24361 agaaaaaggc tcagaaaacg aaataaataa ggaggaatct ggtaatggta gtatttacag
    24421 gttcaactgt tgaagaagca atccagaaag gattgaaaga attagatatt ccaagaatga
    24481 aggctcatat caaagtcatt tctagggaga aaaaaggctt tcttggtcta tttggtaaaa
    24541 aaccagccca agtggatatt gaagcgatta gtgaaacgac tgttgtcaaa gcaaatcaac
    24601 aggtagtaaa aggcgttccg aaaaaaatca atgatttgaa cgagcctgtg aagacggtta
    24661 gtgaagaaac cgttgacctt ggtcatgtgg ttgatgctat taaaaaaata gaggaagaag
    24721 gtcaaggtat ttctgatgaa gtcaaggctg aaatcttaaa acatgaaaga catgccagca
    24781 ctatcttaga agaaactggt cacattgaga ttttaaatga acttcaaatc gaggaagcga
    24841 tgagggaaga agcaggcgct gatgaccttg aaactgagca agatcaaact gaaaatcaag
    24901 acttgaaaga gatgggcttg aaggtcgagc aaagttatga tattgcccag gtggctacgg
    24961 atgtgactgc ctatgttcaa gcgattgtgg atgacatgga tgttgaagct acactttcaa
    25021 atgattataa ccgtcgtagc atcaatctac aaattgacac caacgaacca ggtcgtatta
    25081 tcggctacca tggtaaagtc ttgaaggcct tgcaactgtt ggctcaaaat tatctttaca
    25141 accgctattc cagaaccttc tacgttacaa tcaatgtcaa tgattatgtc gaacaccgtg
    25201 cagaagtctt gcagacctat gcgcaaaaat tggcgactcg tgttttggaa gaagggcgca
    25261 gtcataaaac agatccaatg tcaaatagcg aacgcaagat tatccatcgt attatttcac
    25321 gtatggatgg cgtgactagt tactctgaag gtgatgagcc aaatcgctat gttgttgtag
    25381 atacagaata agtaaaatca ggtttatcct gattttttgc tagttagagg aggttaaact
    25441 gatgttgaat aagataagag actatttaga ctttgctggt ttgcagtacc gtaatcctga
    25501 taaagcggga gcagagcgag agaagatgct ggcattccgc cacaaaggac aagaggcccg
    25561 aaaggctttt acagaactgg ccaaagcctt tcaagcaagc catccagaat ggcaactcca
    25621 acagactagc cagtggatga atcaggccca gcgtttgaga ccacattttt gggtttatct
    25681 acagagagac ggacaagtga cagaacctat gatggcctta cgtttgtatg ggacatctac
    25741 tgactttgga atttctttgg aagtcagttt catcgaacgt aagaaggatg agcaaacact
    25801 gggcaagcag gccaaagttt tagacattcc aaccgttaaa gggatttatt atctaaccta
    25861 ctctaatggt caaagtcaac ggtgggaggc gaatgaagaa aagcgtcgta ctttacgcga
    25921 gaaggtgaga agtcaagaag ttcgaaaagt tttagtgaag gtagatgttc ctatgacaga
    25981 aaattcgtct gaagaagaaa tcgtagaagg cttattgaag tcttattcta aaattcttcc
    26041 ctattatcta gctacgagaa aataagataa tttgtaaaac atcataaatc atacagtcca
    26101 agagtgaaca gtccgctgtg taattcttgg tctttttgtt tgcgctttcg cattatataa
    26161 taaacttaca aaaacaattc aaaaggagaa caattatgga agtcgtttca agtgttctaa
    26221 attggttttc tagcaatatt ttgcagaatc ccgcattttt cgtaggttta ttggtgttga
    26281 taggatatgc acttttgaaa aaacctgccc atgacgtttt ttcagggttt gttaaagcaa
    26341 cagtagggta tatgttgctt aacgtgggtg ctggtggttt ggttacaacc tttcgtccaa
    26401 tcttagcagc tcttaactac aaattccaaa ttggtgcagc ggttatcgac ccttactttg
    26461 gacttgctgc agcaaacaac aaaattgcag cagagtttcc agattttgtt ggaactgcaa
    26521 ctacagctct attgattggt tttggaataa atatcttgct cgtagctctt cgaaagatta
    26581 cgaaggtaag aaccctcttt attactggtc acatcatggt acaacaagct gcaacagtat
    26641 ctcttatggt tctattctta gtaccacaat tgcgcaatgc ttacggtaca gcagcgattg
    26701 gtatcatctg tggactttac tgggcagtta gttcaaatat gactgttgag gcaactcaac
    26761 gcttgactgg tggtggcgga tttgcgattg gtcaccaaca gcaatttgca atctggtttg
    26821 tagataaagt agcaggacgc tttggtaaga aagaagaaag tttagacaat cttaaattac
    26881 ctaagttcct ctcaatcttc cacgatacag ttgttgcatc tgctaccttg atgctcgtat
    26941 tcttcggagc cattctttta atcttgggtc cagacattat gtctaataaa gaagtcatca
    27001 cttcaggaac tctattcaat cctgctaaac aagatttctt tatgtacatt atccaaacag
    27061 cctttacctt ctcagtttac ttgttcgttt tgatgcaagg tgtccgaatg ttcgtatctg
    27121 agttgacaaa cgccttccaa ggtatttcaa acaaattgtt gccaggttca ttcccagcgg
    27181 ttgacgttgc agcttcttat ggatttggtt ctccaaatgc tgtcttgtca ggatttacct
    27241 ttggtttgat tggtcaattg attacaattg tcttgctcat cgtctttaaa aatccgattc
    27301 ttattattac aggatttgta ccagtgttct ttgacaatgc agccattgcg gtctacgctg
    27361 ataaacgcgg cggatggaaa gcggctgtta tcctttcctt tatatcaggt gtccttcaag
    27421 ttgctctagg agctctttgt gtggcccttc tcgatttggc atcttatggt ggctaccatg
    27481 gaaatatcga ctttgaattc ccatggcttg gatttggata tatcttcaaa taccttggta
    27541 ttgttggtta tgtacttgtg tgtctcttct tgcttgttat tcctcaactt caatttgcca
    27601 aagcaaaaga taaagagaaa tattacaacg gtgaagttca agaagaagct tagtatctag
    27661 aaaaggagaa ataaaatggt taaagtatta gcagcgtgcg gaaatggaat gggttcatca
    27721 atggttatca agatgaaggt tgaaaatgct ctccgtaagc ttaatcaaac agattttaca
    27781 gtcaattcat gcagtgtcgg tgaagctaaa ggtttagcag taggatatga catcgtaatc
    27841 gcttctcttc atttgattca agaattggaa gggcgaacta atgggaagtt aattggtctt
    27901 gataacttga tggatgataa agaaatcacc gaaaaactca gtcaagcact acagtaaaag
    27961 gttggagggg gctggacaga aactgagagt tatcgtttct gtccttctcc ctctttaaat
    28021 aaaggaggca gatatgaatt taaaacaagc tttaattgac aatgactcga tccgactagg
    28081 tttagaggct aacaattgga aagaagcagt caaggtagca gtagatcccc taattgaaag
    28141 tggggcaatt ttgccagagt attacgatgc tatcattgaa tcgactgaag agtatgggcc
    28201 ttactatatc ttgatgccag gtatggctat gccccacgct agacctgaag ctggtgtgca
    28261 aagtgatgcc ttttcattga ttaccttaca aaatcctgtt gtattttcag atgggaaaga
    28321 ggtatctgtt ttgttggcac tagcagcaac aagttcaaaa attcacacaa gtgtagccat
    28381 tccacaaatt attgccctgt ttgaattaga agattctatt gcacgtttac aggcttgcca
    28441 gactaaagaa gatgtcttgg ctatgattga agaatctaag gatagccctt atctcgaagg
    28501 attggatttg gaaagttaga aagaggaata aagaaatgac aaaaagaata cctaatttac
    28561 aagttgcatt agaccattca gacttgcaag gagcgattaa agcagctgtt tctgttggtc
    28621 aggaagtaga tattatcgaa gctggaactg tttgcttgct tcaagttgga agtgaactgg
    28681 ctgaagtctt gcgtagcctt ttcccagata agattattgt ggcagacaca aaatgtgctg
    28741 atgctggtgg aacagttgct aaaaataatg cggttcgtgg agcagactgg atgacttgta
    28801 tctgttgtgc aaccatccct actatggaag cagctctaaa ggctatcaag actgaacgag
    28861 gagaacgagg cgaaatccag atcgagcttt atggcgattg gacttttgaa caagctcagc
    28921 tttggctaga tgcaggtatc tcacaagcta tttatcacca atctcgtgat gctcttcttg
    28981 ctggtgaaac ttggggtgaa aaagacctta ataaggttaa aaaactcatt gacatgggct
    29041 tccgtgtatc tgtaacaggt ggtctagatg tagatactct caaactcttt gaaggtgttg
    29101 atgtctttac ctttatcgca ggtcgtggaa ttacagaggc tgcggatcca gcaggagcag
    29161 cgcgtgcctt caaggatgaa atcaaacgaa tttgggggta aatcatggta cgtccaattg
    29221 gaatttatga aaaggcaacc ccaacacact ttacttggct agaacgttta aattttgcca
    29281 aggagttagg ctttgatttt gtcgagatgt ctattgacga acgtgacgag cgtttagcaa
    29341 gacttgactg gagtaaggaa gaacgcttgg aagttgtcaa agcaatctat gaaactggtg
    29401 ttcgtattcc ttctatctgt ttttcaggcc atcgtcgcta cccattgggt tcaaaagatc
    29461 cagttctaga ggaaaaatct ctagaactca tgaaaaaatg tatcgaatta gctcaagact
    29521 tgggagttcg tacgattcaa ttagctggtt acgatgttta ctatgaggaa aagtcacccc
    29581 agacacgcca acgttttatc aaaaatttga gaaaagcctg tgactgggct gaagaagctc
    29641 aggtggtact tgctattgaa attatggatg atcctttcat cagtagcatc gaaaaatatt
    29701 tggctataga aaaagagatt gactctccct tcctctttgt atatccagat attggtaatg
    29761 tgtctgcatg gcataatgat atctatagtg agttttatct tggtcatcat gccatcgcag
    29821 ctctccatct caaggatact tatgcagtga cagaaagttc aaagggccag ttccgagatg
    29881 tacctttcgg gcaaggttgt gtcaaatggg aagaagcttt cgatatttta aaggaaacca
    29941 attataatgg acctttccta atcgaaatgt ggtctgaaaa ttgtgaaaca gtagaagaaa
    30001 cacgcgcagc cgttcaagag gcgcaagctt ttctctatcc actcattaag aaagcaggtt
    30061 tgatgtaaga tgaatcaagt aatcaatgct atgcgtaaac gagtctgtga tgccaatcaa
    30121 tcattgccaa aacatggact tgtcaaattt acctggggga atgtatctga agttaatcgc
    30181 gaactcggtg tcattgttat caaaccatca ggcgtggatt atgacgaatt gacacctgaa
    30241 aacatggtag tgactgatct agatggtaag atcctagaag gggatttaag accatcttcc
    30301 gacctcccaa ctcatgtgca attatataag gcttggtcag aaattggtag tgtggttcac
    30361 acccattcga cagaagctgt tggttgggct caggcaggtc gtgatattcc tttctacgga
    30421 acaacccatg cagattattt ctacggttca atcccttgcg cccgtagttt gaccaaggac
    30481 gaagtagaag tggcctatga aaaagatact ggcctggtta tcgtagaaga gtttgaacat
    30541 cgcggactta acccggttga agtaccagga attgttgtac gcaatcacgg tccattcacc
    30601 tggggcaaaa atccagagaa tgctgtttat cactctgtcg tactagagga agtatcaaag
    30661 atgaatcgct ttacagaaca aatcaatcca agagttggac ctgctcccca gtacatacta
    30721 gaaaaacact accaacgtaa acatggacca aatgcttatt atggtcaaaa gtaagaacga
    30781 tgaaggagga gaaaaagata aatttagctc ctctttttac atttgatttt tattgagagt
    30841 aaagttggaa ttgaagtaat tttaaaagat tttttagaaa tagcgcttga tatatatatg
    30901 gtaaaataaa aagaattgct gtgatatcaa tagatttggg ggatttttta atatggtact
    30961 ggataaggca agttgtgatt tgcttcaata tttgatggat caagaaacgt ccaaaacgat
    31021 tatggcgatt tcgaaagatt tgaaagagtc aagaaggaaa atttattatc acattgacaa
    31081 aatcaatgct gctctgggtg acgaggcgct tcacatcatt agtattccac gaattggtat
    31141 tcacttaacg gaagagcaga gagatgcttg ttgtaaacta ttatcggaag tagattcgta
    31201 cgattatatc atgagtgcgc atgaacgtat gatgataatg ttactatgga taggtatttc
    31261 taaagaacgt attacgattg aaaaattgat agagttaaca gaggtatcta ggaatactgt
    31321 tctcaatgat ttgaatagta ttcgttatca actaactttg gaacaatatc aggtgatctt
    31381 gcaagtgagc aagtcacagg gataccacct tcatgcccac cctcttaata aaattcagta
    31441 tcttcaatcg cttctatatc atatttttat ggaagaaaat gccacttttg tatctatttt
    31501 agaagataag atgaaagaga ggttagatga tgagtgtttg ctttctgttg aaatgaacca
    31561 attttttaag gaacaggttc ctttagttga acaagattta gggaagaaaa taaaccatca
    31621 tgaaataact tttatgttgc aggttctacc ttatttgctg ttaagctgtc ataatgttga
    31681 acagtatcaa gaaagacatc aggatataga gaaagaattt tctttgataa gaaaaagaat
    31741 agagtatcag gtgtctaaga aattaggaga acggttgttt caaaagtttg aaatttcttt
    31801 gtcaggactt gaagtttctc ttgtagctgt tctcctcctc tcctatcgta aagatttgga
    31861 tattcatgca gaaagtgatg attttcggca attaaaactt gctttagaag aatttatctg
    31921 gtattttgaa tcacaaatcc gaatggagat tgagaacaag gatgatttgt tacgaaattt
    31981 gatgatccac tgtaaagcct tgttatttag aaagacttac ggtatttttt ctaaaaatcc
    32041 tctaacaaaa caaattcgat ccaagtatgg agaattattt ttagtcacta gaaaatctgc
    32101 ggaaatttta gaaggagcat ggtttattcg gctaacagac gatgatattg cctatttgac
    32161 gattcatatt ggaggatttt taaaatatac accatcgtct caaaaaaata tgaaaaaagt
    32221 ttatctcgtt tgtgatgaag gtgttgcggt ttcgagactt ttgctgaaac aatgcaaact
    32281 ttattttcca aatgagcaaa ttgacactgt atttacaaca gaacaattta agagtgtgga
    32341 agatattgca caagttgatg tagtgattac tactaatgat gatttggata gcagatttcc
    32401 gattttaagg gttaatccta tccttgaagc agaagatatt ttgaaaatgc tagactatct
    32461 taaacacaat atatttcgta ataagagcaa aagtttcagt gaaaatcttt ctagtcttat
    32521 ttcgtcttat attgtagata gcaagttggc tagtaagttc caagaagagg ttcaaacact
    32581 tataaatcaa gaaatagtag ttcaagcttt tttggaagat atttgaagga cagtccaatg
    32641 atgaacacaa acctgtgttt ttcttggtct tttttagtgt tttgaagggt ggtatactaa
    32701 tctcaaagat aacaattata tccaaaggag gcaacatatg ccaaacgtca aagaaattac
    32761 aagagagtca tggattttag ccactttccc agagtgggga acatggttga acgaagaaat
    32821 cgaagaagaa gtcgtacctg aaggcaactt tgccatgtgg tggctaggca actgtggtac
    32881 ttggattaag acaccagctg gtgctaacgt tgtcatggac ctttggtcaa accgtggaaa
    32941 atcaaccaaa aaagtgaaag atatggttcg tgggcaccaa atggcaaata tggcaggtgt
    33001 tcgtaagttg caaccaaact tgcgtgttca gccaatggtt atcgatccat ttgctatcaa
    33061 cgaactagac tattacttag tttcacactt ccacagtgat catatcgacc catacacagc
    33121 tgcagcaatt ctcaacaatc ctaagttaga gcatgttaag tttatcggtc cttaccactg
    33181 tggacgaatc tgggaaggat ggggtgttcc aaaagaacgt atcatcgttg ttaaaccagg
    33241 tgacactatc gaattaaaag atatgaagat tcatgcagta gaatcatttg accgtacttg
    33301 cttggtaact ctcccagtga acggtgctga tgagacaggc ggtgaacttg ctggcttggc
    33361 tgttacagat gaagaaatgg ctcaaaaggc tgttaactat atctttgaaa caccaggtgg
    33421 aaccatctat catggtgcag attctcactt ctcaaactat tttgcaaaac atggtaaaga
    33481 ctttaaaatt gatgttgctt tgaataacta tggtgaaaat ccggtaggta tccaagacaa
    33541 aatgacatct atcgaccttc ttcgtatggc agaaaatctg cgtaccaaag tcattatccc
    33601 agttcactat gatatctggt ctaacttcat ggcttctact aatgagattc tagaactttg
    33661 gaaaatgcga aaagatcgct tgcaatacga tttccatcca tttatctggg aagttggcgg
    33721 taagtacact tatcctcaag atcaacactt agtagaatac catcatccac gtggttttga
    33781 tgattgtttt gaacaagact ctaacattca atttaaagct ttgctataat ataaaaatat
    33841 tctttggagg ttatccgtat gttgcatgat acggataatt ttcatataat agtaaaatag
    33901 aatgtgtgat tcaataatca cctcaaatag aaaggaaatt ctatgtcaaa tctatctgtt
    33961 aatgcaattc gttttctagg tattgacgcc attaataaag ccaactcagg tcatccaggt
    34021 gtggttatgg gagcggctcc gatggcttac agcctcttta caaaacaact tcatatcaat
    34081 ccagctcaac caaactggat taaccgcgac cgctttattc tttcagcagg tcatggttca
    34141 atgctccttt atgctcttct tcacctttct ggttttgaag atgtcagcat ggatgagatt
    34201 aagagtttcc gtcaatgggg ttcaaaaaca ccaggtcacc cagaatttgg tcatacggca
    34261 gggattgatg ctacgacagg tcctctaggg caagggattt caactgctac tggttttgcc
    34321 caagcagaac gtttcttggc agccaaatat aaccgtgaag gctacaatat ctttgaccac
    34381 tatacttacg ttatctgtgg agacggagac ttgatggaag gtgtctcaag cgaggcagct
    34441 tcatacgcag gtttgcaaaa acttgataag ttggttgttc tttatgattc aaatgatatc
    34501 aacttggatg gtgagacaaa ggattccttt acagaaagtg ttcgtgaccg ttacaatgcc
    34561 tacggttggc atactgcctt ggttgaaaat ggaacagact tggaagccat ccatgctgct
    34621 atcgaaacag caaaagcttc aggcaagcca tctttgattg aagtgaagac ggttattgga
    34681 tacggttctc caaacaaaca aggaactaat gctgtacacg gcgcccctct tggagcagat
    34741 gaaactgcat caactcgtca agccctcggt tgggactacg aaccatttga aattccagaa
    34801 caagtatatg ctgatttcaa agaacatgtt gcagaccgtg gcgcatcagc ttatcaagct
    34861 tggactaaat tagttgcaga ttataaagaa gctcatccag aactggctgc agaagtagaa
    34921 gccatcatcg acggacgtga tccagtcgaa gtgactccag cagacttccc agctttagaa
    34981 aatggttttt ctcaagcaac tcgtaattca agtcaagatg ccttgaatgt tgtggcagct
    35041 aaattaccaa ccttcctagg tggatcagct gaccttgctc actcaaacat gacttatatc
    35101 aagacggatg gacttcaaga cgataccaat cgcttgaatc gtaacattca gtttggtgtt
    35161 cgtgaatttg caatgggaac aatcttgaac gggatggccc ttcatggtgg acttcgtgta
    35221 tacggtggaa ctttcttcgt cttctctgac tatgtgaagg cagctgtccg tttgtcagcc
    35281 ttacaaggac ttcctgtgac ttatgtcttt acccatgatt caatcgcagt tggggaagat
    35341 ggtccgactc acgaaccagt tgagcattta gcaggtcttc gtgctatgcc aaatctaaat
    35401 gttttccgtc cagcagatgc gcgtgaaacg caagcagctt ggtaccttgc agtgacaagt
    35461 gagaaaacac caactgccct tgtcttgaca cgtcaaaact tgactgttga agatggaaca
    35521 gacttcgaca aggttgctaa aggtgcttat gttgtatatg aaaatgcagc cgactttgat
    35581 accatcttga ttgcgacagg ttcagaggtt aatcttgctg tctcagctgc taaagaattg
    35641 gctagtcaag gcgaaaaaat ccgcgtagtc agcatgccat ctacagatgt ctttgataaa
    35701 caagatgcag cttacaagga agaaattctt ccaaatgcag tccgccgtcg tgttgcagtc
    35761 gaaatgggtg caagtcaaaa ctggtacaaa tatgttggtc tcgatggtgc cgttctaggt
    35821 attgatacct tcggagcctc tgccccagca ccaaaagtat tggcagaata tggctttact
    35881 gtcgaaaatc ttgtaaaagt tgttcgaaat ttgaaataat cctaaaaatc agggcgtaag
    35941 ctctggtttt tcttaccaga aaagtaaggt acaatcttgt aaaagtagct gaaatttgat
    36001 atagtagtcc tatgtaaaag acaaaggaga aaacaatgaa tccaaatatt acttttttaa
    36061 tcatgcttgt aggtatgatg gccttgatgt tctttatgca acgttctcaa aagaaacaag
    36121 ctcaaaagcg tatggaaagc ttaaataaac tacaaaaagg ctatgaagtg attacaatcg
    36181 gtggacttta tggaacagtc gatgaagtag atacggagaa gggaacaata gttcttgacg
    36241 tagatggagt ttacttgact tttgaactag ctgctatcaa gacagtatta ccgctgaaag
    36301 aaacagcttc actagaaggc gcaattgaaa aataagacgg gatcacgaac tcccgttttc
    36361 tataaaagaa aggaaatggg atgaaaaaat tagtctttgt ctgtctggga aatatttgcc
    36421 gtagccctat ggccgagttt gttatgaaat caatgacaga taactacgaa atccaaagtc
    36481 gagcaacttc ctcttgggaa catggcaatc cgattcataa ggggactcag ggaatttttc
    36541 aagagtatga gattccttat gacaagaaca agacatcgct tcagattagt aaggaagatt
    36601 ttgaagcctt tgattatatt atcggaatgg acgcttcaaa tatttctgac ttacgtcaga
    36661 tgtgtccagt agactgtcaa gataagattt actcattttc atctgaaagt gttccagacc
    36721 cttggtatac aggagatttt gaagaaacct atcgacgtgt tcaagagggc tgtcaagctt
    36781 ggttagaacg tttagaaaag gagagttaag gtggaaaatc ttacgaattt ttacgaaaag
    36841 tatcgtgtct atctgactcg tccacgttta gagcttttgg cagtagttac cattgttttc
    36901 tgtgctgtac tcgtcttttt tctaaatatt ccaggaaaag gtgtcttaaa actcgataat
    36961 ggaacgattg tttatgatgg cagtcttgtc cgtggtaaaa tgaatggcca aggtaccatt
    37021 accttccaaa atggagacca atatacaggt ggcttcaaca atggagcctt caacggaaaa
    37081 ggtacctttc aatctaaaga aggctggacc tacgaaggtg attttgtaaa tggtcaggct
    37141 gaaggaaaag ggaaactaac aacagaacaa gaagtcgttt atgaaggaac ttttaaacaa
    37201 ggcgtttttc aacaaaaata aagcctccta tcaaaggagg tattattaga atcacaaggt
    37261 aagcgcttac ctgtgaatcc ctttctttcc aaatccctct tccaagcaag tttgtgaaat
    37321 aaaaaatatt tgaaataaat ttcacaaact tcaaagataa aacttgataa gaaaagaaaa
    37381 tgagaaaagt ttcacaagag tttaaaaatt ctttgtgaaa tgtttatgaa actgtttaca
    37441 aagttgaaat aatgcgttat aataaacttg tgaaaaaatt aacaaaggat atcgttcctt
    37501 gaaagctatg gaggaaaata tggctgataa aaaaactgtg acaccagagg aaaagaaact
    37561 cgttgctgaa aaacacgtag atgagttggt tcaaaaagct ctagttgccc ttgaagaaat
    37621 gcgtaaattg gatcaagaac aagttgacta catcgttgcc aaagcatcag tagcagcttt
    37681 ggatgcccac ggagaattgg ctttacatgc ctttgaagaa acaggacgtg gtgtatttga
    37741 agacaaagca actaagaact tgtttgcttg tgaacacgta gtaaacaaca tgcgccacac
    37801 taagacagtt ggcgttatcg aagaagacga tgtaacagga ttgactctta ttgctgaacc
    37861 agttggtgtt gtttgtggta ttactccaac aacaaaccca acatcaacag caatcttcaa
    37921 atcattgatt tcattgaaga cacgtaaccc aatcgtcttt gccttccatc catcagcaca
    37981 agaatcatct gctcatgcag ctcgtatcgt ccgcgatgca gctatcgcag ctggtgctcc
    38041 tgaaaactgt gtacagtgga tcactcaacc atctatggaa gcaactagtg cccttatgaa
    38101 ccacgaaggt attgcaacaa tccttgcaac aggtggtaat gccatggtta aagccgcata
    38161 ctcatgtggt aaaccagctc ttggggtagg tgccggaaac gttccagctt atgttgaaaa
    38221 atcagcaaac attcgtcaag cagcacacga tatcgtcatg tctaaatcat ttgataacgg
    38281 tatggtctgt gcatctgaac aagcagttat cattgataaa gaaatttacg atgaatttgt
    38341 agcagagttc aaatcttacc acacttactt tgtaaacaaa aaagaaaaag ctcttcttga
    38401 agagttctgc ttcggcgtca aagcaaacag caaaaactgt gctggtgcaa aattgaacgc
    38461 tgacatcgtt ggtaaaccag caacttggat tgcagaacaa gcaggattta cagttccaga
    38521 aggaacaaac attcttgctg cagaatgtaa agaagttggc gaaaatgagc cattgactcg
    38581 tgaaaaattg tcaccagtta ttgcagtttt gaaatctgaa agccgtgaag atggtattac
    38641 taaggctcgt caaatggttg aatttaacgg tcttggacac tcagcagcta tccacacagc
    38701 tgacgaagaa ttgactaaag aatttggtaa agctgttaaa gctattcgtg ttatctgtaa
    38761 ctcaccttct acttttggtg gtatcgggga cgtttacaat gccttcttgc catcattgac
    38821 acttggatgt ggttcttacg gacgcaactc agttggggat aacgttagtg ccattaacct
    38881 cttgaatatc aaaaaagtcg gaagacggag aaataacatg caatggatga aacttccttc
    38941 aaaaacatac tttgaacgtg attcaattca ataccttcaa aaatgtcgtg acgttgaacg
    39001 tgtcatgatc gttactgacc atgccatggt agagcttggt ttccttgatc gtatcatcga
    39061 acaactggac cttcgtcgca ataaggttgt ttaccaaatc tttgcggatg tagaaccgga
    39121 tccagatatc acaactgtaa accgtggtac tgagattatg cgtgccttca aaccagatac
    39181 catcatcgca ctcggtggtg ggtctccaat ggatgctgcc aaagtaatgt ggctcttcta
    39241 cgagcaacca gaagtggact tccgtgacct tgtccaaaaa ttcatggata tccgtaaacg
    39301 tgccttcaag ttcccattgc ttggtaagaa gactaaattc atcgcgattc caactacatc
    39361 tggtacagga tctgaagtaa caccatttgc cgttatctct gataaagcaa acaaccgtaa
    39421 atacccaatc gctgactact cattgacacc aactgtggca atcgtagatc ctgctttggt
    39481 attgacagtt ccaggatttg ttgctgctga tactggtatg gacgtattga ctcacgcgac
    39541 agaagcatac gtatcacaaa tggctagtga ctacactgat ggtttagcac ttcaagccat
    39601 taaattggtc tttgaaaatc tcgaaagctc agttaagaat gcagacttcc actcacgtga
    39661 gaaaatgcat aacgcttcaa caatcgctgg tatggccttt gccaatgcct tcctaggtat
    39721 ttctcactca atggcccata agattggtgc gcaattccac acaatccacg gtcgtacaaa
    39781 tgctatcttg cttccatacg ttatccgtta caacggtaca cgtccagcta agacagcaac
    39841 atggcctaag tacaactact accgtgcaga tgaaaaatac caagatatcg cacgcatgct
    39901 tggacttcca gcttctactc cagaagaagg ggttgaatct tacgcaaaag ctgtctacga
    39961 actcggtgaa cgtattggga tccaaatgaa ttttagagac caaggaattg acgaaaaaga
    40021 atggaaagaa cattctcgtg aattagcctt cctggcttat gaagaccaat gttcaccagc
    40081 taacccacgt cttccaatgg tagaccatat gcaagaaatc atcgaagatg catactatgg
    40141 ctacaaagaa agaccaggac gccgtaaata attgtttatc agtctagaag caagacaaaa
    40201 actcaatttg agggaaagat ccagtacttt ttctatgata aaaggcatcc tatcaaggtt
    40261 tttgaacacc tgataggatg cctttttatg atattgaggc ctttttgccc tttttgaaaa
    40321 actagaatag aaacaaaata tataatagat tgaaactgga atagtacact tctgcttcta
    40381 aaacattgtt agaattcgat ttgactgtcc tgatcgattt gtcctgttct tatttcattt
    40441 taatatataa aaaatat
//
LOCUS       DAVBOG010000015        38741 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.015, whole genome shotgun sequence.
ACCESSION   DAVBOG010000015 DAVBOG010000000
VERSION     DAVBOG010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38741)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38741)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38741
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.015"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(2..1681)
                     /locus_tag="VQ865_000845"
     CDS             complement(2..1681)
                     /locus_tag="VQ865_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3135214.1"
                     /translation="MAYTLKPEEVGVFAIGGLGEIGKNTYGIEYQDEIIIVDAGIKFP
                     EDDLLGIDYVIPDYSYIVDNIDRVKAVLITHGHEDHIGGIPFLLKQANVPIYAGPLAL
                     ALIRGKLEEHGLLRNAKLYEINHNTELTFKNLKATFFRTTHSIPEPLGIVIHTPQGKI
                     ICTGDFKFDFTPVGEPADLHRMAALGEDGVLCLLSDSTNAEVPTFTNSEKVVGQSIMK
                     IIQGIEGRIIFASFASNIFRLQQATEAAVKTGRKIAVFGRSMEKAIVNGIDLGYIKAP
                     KGTFIEPNEIKDYPAGEILILCTGSQGEPMAALSRIANGTHRQVQLQPGDTVIFSSSP
                     IPGNTTSVNKLINIISEAGVEVIHGKVNNIHTSGHGGQQEQKLMLRLIKPKYFMPVHG
                     EYRMQKVHAGLAVDTGVEKDNIFIMSNGDVLALTADSARIAGHFNAQDIYVDGNRIGE
                     IGAAVLKDRRDLSEDGVVLAVATVDFKSQMILSGPDILSRGFVYMRESGDLIRQSQRI
                     LFNAIRIALKNKDASVQSVNGAIVNAIRPFLYENTEREPIIIPMILTPDEE"
     gene            complement(1683..1916)
                     /locus_tag="VQ865_000846"
     CDS             complement(1683..1916)
                     /locus_tag="VQ865_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HET3135215.1"
                     /translation="MIYKVFYQETKERSPRRETTRALYLDIDASSELEGRIAARQLVE
                     ENRPEYNIEYIELLSDKLLDYEKETGAFKITEF"
     gene            complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ865_000847"
     CDS             complement(2722..2874)
                     /gene="cibB"
                     /locus_tag="VQ865_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000977347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibB"
                     /protein_id="HET3135216.1"
                     /translation="MMKNLNNYREISNKELQEIKGGFGVGVGIALFMAGYTIGKDLRK
                     KFGKSC"
     gene            complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ865_000848"
     CDS             complement(2876..3061)
                     /gene="cibA"
                     /locus_tag="VQ865_000848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000180803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fratricide two-peptide bacteriocin subunit CibA"
                     /protein_id="HET3135217.1"
                     /translation="MTNFDILDNQFLSLSENELSDIDGGLAPLVIFGVAVSWKAIAGG
                     TALIGSGLAAGYFLGGD"
     gene            3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ865_000849"
     CDS             3239..3922
                     /gene="tsaB"
                     /locus_tag="VQ865_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HET3135218.1"
                     /translation="MKVLAFDTSSKALSLAILEDKQILAEMTINIKKNHSITLMPAID
                     FLMASLDWTPKDLDRIVVAEGPGSYTGLRIAVATAKTLAHTLNIELVGMSSLLALVPY
                     QQEGLFVSLMDARRNNVYAGFYENAKPVMPEAHLPFERVIELIKGASQVTFVGEVGPF
                     VEQIQEYLPRTNFKETLPNAANLALWAWDKEADSLHDFVPNYLKRVEAEENWLKNHTE
                     SGESYIKRL"
     gene            3919..4356
                     /gene="rimI"
                     /locus_tag="VQ865_000850"
     CDS             3919..4356
                     /gene="rimI"
                     /locus_tag="VQ865_000850"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HET3135219.1"
                     /translation="MIEIKRIQKHPDLAQAIYAVMIAVYPVSPWTLEQIQADLSQDQT
                     WYALAYDGAEVIGFLAVQENLFEAEVLQIAVKGAYQSQGIASALFAQLPTDKEIFLEV
                     RQSNQRAQAFYKKEKMAVIAERKAYYHDPVEDAIIMKREIDEG"
     gene            4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ865_000851"
     CDS             4346..5356
                     /gene="tsaD"
                     /locus_tag="VQ865_000851"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002896630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HET3135220.1"
                     /translation="MKDRYILAFETSCDETSVAVLKNDDELLSNVIASQIESHKRFGG
                     VVPEVASRHHVEVITACIEEALAEAGITEEDVTAVAVTYGPGLVGALLVGLSAAKAFA
                     WAHGLPLIPVNHMAGHLMAAQSVEPLEFPLLALLVSGGHTELVYVSEAGDYKIVGETR
                     DDAVGEAYDKVGRVMGLTYPAGREIDDLAHQGQDIYDFPRAMIKEDNLEFSFSGLKSA
                     FINLHHNAEQKGESLSTEDLCASFQAAVMDILMAKTKKALEKYPVKTLVVAGGVAANK
                     GLRERLAAEITDVKVIIPPLRLCGDNAGMIAYASVSEWNKENFAGWDLNAKPSLAFDT
                     ME"
     gene            complement(5396..6702)
                     /locus_tag="VQ865_000852"
                     /pseudo
     CDS             complement(5396..6702)
                     /locus_tag="VQ865_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011680908.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(7036..7330)
                     /locus_tag="VQ865_000853"
                     /pseudo
     CDS             complement(7036..7330)
                     /locus_tag="VQ865_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7437..7730)
                     /locus_tag="VQ865_000854"
                     /pseudo
     CDS             complement(7437..7730)
                     /locus_tag="VQ865_000854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
     gene            7973..9177
                     /locus_tag="VQ865_000855"
                     /pseudo
     CDS             7973..9177
                     /locus_tag="VQ865_000855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200043.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
     gene            9170..10046
                     /locus_tag="VQ865_000856"
                     /pseudo
     CDS             9170..10046
                     /locus_tag="VQ865_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375706.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            10133..11749
                     /locus_tag="VQ865_000857"
     CDS             10133..11749
                     /locus_tag="VQ865_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135221.1"
                     /translation="MYTIIKSNIKKFSLLTIFIVAGQLLLIYAATINALVLNELIAMN
                     LERFLKLSIYQMIVWCGIIFLDWVVKNYQVEVIQEFNLEIRNRVATDISNSTYQEFHS
                     KSSGTYLSWLNNDVQTLNDQAFKQLFLVIKGISGTIFAVVTLNHYHWSLTVATLFSLM
                     IMLLVPKIFASKMREVSLNLTNQNEAFLKSSETILNGFDVLASLNLLYVLPKKIKEAG
                     ILLKMVIQRKTTVETLAGAISFFLNIFFQISLVFLTGYLAIKGIVKIGTIEAIGALTG
                     VIFTALGELGGQLSSIIGTKPIFLKLYSINPIESNKMNDIEPNEVNRDFPLYEAKNIC
                     YKYGDKEILKNLNFCFQRNEKYLILGESGSGKSTLLKLLNGFLRDYSGELRFCGDDIK
                     KTSYLNMVSNVLYVDQKAYLFEGTIRDNILLEENYTDEEILQSLEQVGLSVKDFPNNI
                     LDYYVGDDGRLLSGGQKQKITLARGLIRNKKIVLIDEGTSAIDRRTSLAIERKILDRE
                     DLTVIIVTHAPHPELKQYFTKIYQFPKDFI"
     gene            11769..12612
                     /locus_tag="VQ865_000858"
                     /pseudo
     CDS             11769..12612
                     /locus_tag="VQ865_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813546.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            12680..14181
                     /locus_tag="VQ865_000859"
                     /pseudo
     CDS             12680..14181
                     /locus_tag="VQ865_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819023.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase"
     gene            14193..14942
                     /locus_tag="VQ865_000860"
     CDS             14193..14942
                     /locus_tag="VQ865_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000069862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HET3135222.1"
                     /translation="MSDNTKYIFLSPHLDDAIFSCGDYISKLTSEGEIVLVITIFSGY
                     PLSQQLQPSAKQFHKLCNLGKYPIEERKKEDRLACERLQCDFRHLSYYECLYRKDRNG
                     NFLYRHIYSKLKNEDTLKNDIIKELLMHLDDKCVVYCPLSLGDHVDHVFVNSIGRALE
                     FMRYKVIYYEDFPYVSDSSMVSYMGKTKELKMYQEELDEKHYIDRISSILCYKSQILI
                     IWKSVEKLLNNIKELYLRNGAAYSIRFWIKK"
     gene            14955..16127
                     /locus_tag="VQ865_000861"
     CDS             14955..16127
                     /locus_tag="VQ865_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001017606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3135223.1"
                     /translation="MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGTLP
                     SKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIALPTDYDEKIGSFNTYEIEQTVS
                     KILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
                     GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELD
                     SFAERRSLNAEVVIKGVCLDPRIGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVI
                     EAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESAILSIINELLIVGIK
                     ILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRDLEAYKDKVYTRGIWIRD"
     gene            16522..17385
                     /locus_tag="VQ865_000862"
     CDS             16522..17385
                     /locus_tag="VQ865_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3135224.1"
                     /translation="MIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSM
                     LSADKLILAIQGINMNFDEFGHKLNNYQESPHMRIGRRVVDCFSHQDIAALEQLLEEV
                     DQEQMAQTYRRLNAIVIKNALHSLDKSYPLTEEDSEFLTTYLYAIESWTWFELYLFCN
                     TMPFLSNQDLIFLSTSLLEKSKEFKELVHNRWYMKSGYLNIISELMERKLFSYIPIFE
                     AELERMLRPYDVFEKVLWQFLKKMQIFLQTKGSNQKEIEHFIQSLQVLENPQLTALFE
                     LRLQQYKELID"
     gene            17671..17904
                     /locus_tag="VQ865_000863"
     CDS             17671..17904
                     /locus_tag="VQ865_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135225.1"
                     /translation="MLNLQFAETMELTEAELQDVRGGNLVNSMGGGGRSGISGWGVPG
                     IYPGWGNQGMSPNRGAFDWTIDLADGLFGRRRR"
     gene            17926..18603
                     /locus_tag="VQ865_000864"
     CDS             17926..18603
                     /locus_tag="VQ865_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135226.1"
                     /translation="MKKMKEVKFHLATGLLILTYYLIFNVTSDLDFMVALSDNMYYVF
                     QVLLVLILGTIATIAFVKSEHWKECGRFQFRWSYLGVFLLSFFLLFVWANLTTYIFPR
                     TQNGSTVVEVATSLTGISYFVTRILYTSIIAPVSEEVVCRGLLMTSLSKVNRYYLDVL
                     VSAAIFGAMHVLQYGWITTDFIKYFGMGLIFCMMFRYTRSIYWAIALHASWNSFLLIV
                     TLLVFGY"
     gene            18615..19280
                     /locus_tag="VQ865_000865"
     CDS             18615..19280
                     /locus_tag="VQ865_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000720786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135227.1"
                     /translation="MKKIISHRYFIIVFLLVIADQKFSVLVLRSDLVAGLSDFAYYLS
                     DMMLNFLVVLFALIAMIWSGKWQKINSRKFKGSYLFYSFLALLAFVAWNFVTFFLFPP
                     TRNEISYQHAAPTFTGATAFLMYFFYPVIAGPIFEDMIYRGLVMTALEKGKKWGLDVL
                     GSAVLFGVSHISNHGWVLTDFVFYMGGGLIFAVLFRMTKSIYWPIGLHIVYNGIGQLL
                     MLL"
     gene            19352..20578
                     /locus_tag="VQ865_000866"
     CDS             19352..20578
                     /locus_tag="VQ865_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3135228.1"
                     /translation="MKVFLQNRDFRQLTINQWISTLGDTIFYLAFLNYVADASFAPLA
                     ILLITISETLPQVLQIFLGVLADFQHHRVLKYTVISFTKFLLYSIVSLSLSGQSFSLL
                     LVTFICLINLLSDTLSYFSGAMLTPIFIRIIGQDHLAEAIGFKQSTVSLVKTISNILG
                     GVLLGILSIQFISLLNALTFLIAFLGILFIKTDLLKVEKTISYQEGLSVKSFCQHLLQ
                     SSKLIWNMNKVLLVLFIISTSQAVINVTVPVSTLFLRNQPFLNLQTGQSLALLSTFEL
                     SALIVGSLVSGYLQHTISIKTALYASLVIQLLLLVGFATVRFDWILIFSTLDAFFAGV
                     LSPRLQELVFKQIPEESMGAVQSSISAITVVLPSLFTISLVTIATSFGTLAVSFVLLL
                     FLLVAFVMLLNIRESI"
     gene            21086..22132
                     /gene="pheS"
                     /locus_tag="VQ865_000867"
     CDS             21086..22132
                     /gene="pheS"
                     /locus_tag="VQ865_000867"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HET3135229.1"
                     /translation="MSTIEEQLKALREETLTSLKQITAGNEKEMQDLRVSVLGKKGSL
                     TEILKGMKDVSAEMRPIIGKHVNEARDVLTAAFEETAKLLEEKKVAAQLASESIDVTL
                     PGRPVATGHRHVLTQTSEEIEDIFIGMGYQVVDGFEVEQDYYNFERMNLPKDHPARDM
                     QDTFYITEEILLRTHTSPVQARAMDAHDFSKGPLKMISPGRVFRRDTDDATHSHQFHQ
                     IEGLVVGKNISMADLQGTLQLIVQKMFGEERQIRLRPSYFPFTEPSVEVDVSCFKCGG
                     EGCNVCKKTGWIEIMGAGMVHPRVLEMSGIDATVYSGFAFGLGQERVAMLRYGINDIR
                     GFYQGDVRFSEQFK"
     gene            22132..22641
                     /locus_tag="VQ865_000868"
     CDS             22132..22641
                     /locus_tag="VQ865_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135230.1"
                     /translation="MIRKVEMADVEVLAKIAKQAFRETFAYDNTEEQLQEYFEEAYSL
                     KTLSTELGNPDSETYFIMHEEEIAGFLKVNWGSAQTERELEDAFEIQRLYVLQKFQGF
                     GLGKQLFEFALELATKNSFSWAWLGVWEHNTKAQAFYNRYGFEKFSQHHFMVGQKVDT
                     DWLLRKKLR"
     gene            22718..25120
                     /locus_tag="VQ865_000869"
     CDS             22718..25120
                     /locus_tag="VQ865_000869"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HET3135231.1"
                     /translation="MLISYKWLKELVDIDVPSQELAEKMSTTGIEVEGVESPAAGLSK
                     IVVGEVLSCEDVPETHLHVCQVNVGEEERQIVCGAPNVRAGIKVMVALPGARIADNYK
                     IKKGKIRGLESLGMICSLGELGISDSVVPKEFADGIQILPEDAVPGEEVFSYLDLDDE
                     IIELSITPNRADALSMCGVAHEVAAIYDKAVNFKEFTLTETNEAAADALSVSIETDKA
                     PYYAARILDNVTIAPSPQWLQNLLMNEGIRPINNVVDVTNYILLYFGQPMHAFDLDNF
                     EGTDIRVREARAGEKLVTLDGEERDLDVNDLVITVADKPVALAGVMGGQATEISEKSS
                     RVVLEAAVFNGKSIRKTSGRLNLRSESSSRFEKGINVATVNEALDAAASLIAELAGAT
                     VRKGIVSAGELDTSDVEVSSTLADVNRVLGTELSYADVEDVFRRLGFGLSGNADSFTV
                     RVPRRRWDITIEADLFEEIARIYGYDRLPTSLPKDDGTAGELTATQKLRRQVRTIAEG
                     AGLTEIITYTLTTPEKAVEFTAQPSNLTELMWPMTVDRSVLRQNMISGILDTVAYNVA
                     RKNKNLALYEIGKVFEQTGNPKEELPNEINSFAFALTGLVAEKDFQTAAVPVDFFYAK
                     GILEALFTRLGLQVTYTATSEIASLHPGRTAVISLGDQVLGFLGQVHPVTAKAYDIPE
                     TYVAELNLSAIEAALQPATPFVEITKFPAVSRDVALLLKAEVTHQEVVDAIQAAGVKR
                     LTDIKLFDVFSGEKLGLGMKSMAYSLTFQNPEDSLTDEEVARYMEKIQASLEEKVNAE
                     VR"
     gene            complement(25188..26189)
                     /locus_tag="VQ865_000870"
     CDS             complement(25188..26189)
                     /locus_tag="VQ865_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000597989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3135232.1"
                     /translation="MIKTFLSALSVILFVIPIITYSFFPSSNLNIWLSTQPILAQIYA
                     FPLATATMAAILSFLFFFLSFYKKNKQIRFYSGILLLLSLILLLFGTDKTLSSASNKT
                     KTLKLVTWNVANQIEAQHIERIFSHFDADMAIFPELATNIRGEQENQRIKLLFHQVGL
                     SMANYDIFTSPPTNSGIAPVTVIVKKSYGFYTEAKTFHTTRFGTIVLHSRKQNIPDII
                     ALHTAPPLPGLMEIWKQDLNIIHNQLASKYPKAIIAGDFNATMRHGALAKISSHRDAL
                     NVLPPFERGTWNSQSPKLFNATIDHILLPKNHYYVKDLDIVSFQNSDHRCIFTEITF"
     gene            26345..26792
                     /locus_tag="VQ865_000871"
                     /pseudo
     CDS             26345..26792
                     /locus_tag="VQ865_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            26918..27184
                     /locus_tag="VQ865_000872"
     CDS             26918..27184
                     /locus_tag="VQ865_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135233.1"
                     /translation="MEGCPSELFSKEEILESDMRVAIMSELIEARNKQGISQKKLEEL
                     SGVSQPVIARMETGKTSPQLDTVLKVLASLGKILAVVRLEQGKS"
     gene            27444..29693
                     /gene="metE"
                     /locus_tag="VQ865_000873"
     CDS             27444..29693
                     /gene="metE"
                     /locus_tag="VQ865_000873"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HET3135234.1"
                     /translation="MSTTIIGFPRLGEFRELKFTTEKYFRKEISEEELLAAAKDLRAK
                     HWNIVKEKGITEIPSNDFSHYDNFLDAAFLFNVVPASVQNLDLSDLERYFALGRGYQG
                     EKGDVRALPMKKWFNTNYHYIVPKFEKDTQVKLAGHKIFDEFQEAKELGLNTRPVLVG
                     PFTFLQLSDFEEGVKADDFVDSLVAAYQEVFAKLAELGATRIQLDEAALVKDLTAEEK
                     ALFLNLYNKLLADKKGLEVLLQTYFGDVRDVYADLVNLPVDAIGLDFVEGKKTLELVK
                     GGFPADKTLYVGIVNGKNIWRNNYEKSLAVLEQIPAENIVLTSSCSLLHVPFTTANEE
                     FEPALLNHFAFAVEKLDEIRDLDAIRNGQGSEALAANKELFATERVGENAELRARIAG
                     LTDADYTRLPAFAEREAIQEEAFKLPALPTTTIGSFPQTKEVRAKRLAYRKGELSQKE
                     YDAFLAETIDEWIKWQEDIDFDVLVHGEFERNDMVEYFGQNLSGYFFSKNGWVQSYGM
                     RGVKPPIIWGDVTRLNPITVKWSSYAQSRTNKPVKGMLTGPVTILNWSFPREDISIKD
                     STLQIALAIKDEVLDLEAAGVKIIQIDEAALREKLPLRRSDWYEDYLDWAIPAFRLVH
                     STVASDTQIHTHMCYSEFTDIIPAIDNMDADVISFEASRSNLEILDELKAKNFQTEVG
                     PGVYDIHSPRVPNEGEIDNTIEAILAKVPSKKVWINPDCGLKTRGIPETKESLIRLVE
                     AAKAAREKL"
     gene            29757..30623
                     /gene="metF"
                     /locus_tag="VQ865_000874"
     CDS             29757..30623
                     /gene="metF"
                     /locus_tag="VQ865_000874"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000089969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="HET3135235.1"
                     /translation="MSRQTPSLSFEVFPPNPAVGNGNIISALQDMQELAPHFISVTAS
                     NNKFNIKETTVRLADFIQNDLAIPTIAHLPAIYLTKDKVAETIVDLDKVGVQKILALR
                     GDIIPDVEPQKDFRYATDLIEFIKEQAPHFDIIGACYPEEHPDSPNQISDIQNLKKKV
                     DAGCSSLVTQLFFDNERFYDFQDKCILAGIDVPIHAGIMPILNRNQALRLLKTCENIH
                     LPRKFKAILDKYEHDPESLRAAGLAYAVDQIVDLVTQDVAGVHLYTMNNADTAKYIHQ
                     ATHALFNHQSLG"
     gene            31182..33395
                     /gene="pnp"
                     /locus_tag="VQ865_000875"
     CDS             31182..33395
                     /gene="pnp"
                     /locus_tag="VQ865_000875"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HET3135236.1"
                     /translation="MAKQVFQTTFAGRELIVETGQVAKQANGSVVVRYGESTVLTAAV
                     MSKKMATGDFFPLQVNYEEKMYAAGKFPGGFMKREGRPSTDATLTARLIDRPIRPMFA
                     EGFRNEVQVINTVLSYDENASAPMAAMFGSSLALSISDIPFDGPIAGVQVGYVDGQII
                     INPSQEQAEQSLLELTVAGTKHAINMVESGAKELSEEIMLEALLKGHEAVKELITFQE
                     EIVAAVGKEKAEVELLHVDAELQAEIIAAYNSDLQKAVQVEEKLAREAATQAVKDQVT
                     AVYEEKYANHEEFDRIMRDVAEILEQMEHAEVRRLITEDKVRPDGRKVDEIRPLDAVV
                     DFLPRVHGSGLFTRGQTQALSVLTLAPMGETQIIDGLDPEYKKRFMHHYNFPQYSVGE
                     TGRYGAPGRREIGHGALGERALAQVLPSLEEFPYAIRLVAEVLESNGSSSQASICAGT
                     LALMAGGVPIKAPVAGIAMGLISDGNNYTVLTDIQGLEDHFGDMDFKVAGTRDGITAL
                     QMDIKIQGITAEILTEALAQAKKARFEILDVIEATIPEVRPELAPTAPKIDTIKIDVD
                     KIKIVIGKGGETIDKIIAETGVKIDIDEEGNVSIYSSDQDAINRAKEIIAGLVREAKV
                     DEVYRAKVVRIEKFGAFVNLFDKTDALVHISEMAWTRTNRVEDLVEIGDEVDVKVIKI
                     DEKGRIDASMKALLPRPPKPEHDEKGEKSERPHRPRHQKDHKPKKEFTETPKDSE"
     gene            33411..34028
                     /gene="cysE"
                     /locus_tag="VQ865_000876"
     CDS             33411..34028
                     /gene="cysE"
                     /locus_tag="VQ865_000876"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000539958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HET3135237.1"
                     /translation="MGWWRETIDIVKENDPAARTTLEVLLTYPGVKALAAHRLSHFLW
                     KHGFKLLARMYSQFWRFWTQIEIHPGAQIDSGVFIDHGSGLVIGETAIVEKGVLLYHG
                     VTLGGTGKDCGKRHPTVRKGALISAHAQVIGPVEIGENAKVGAAAVVVADVPSDVTVV
                     GIPAKIVRLHGKKDEPVIHEVEEKREYYVNKLEQAKDASHRSSGL"
     gene            34040..34924
                     /locus_tag="VQ865_000877"
     CDS             34040..34924
                     /locus_tag="VQ865_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135238.1"
                     /translation="MIQARNKLSQEELSEAKKVINCCQNYDGTYRDPYLSNMLNFDPN
                     MPAFFLYYEKGELVGLLTVYADDQDVEVTILVHPGHRRQGIARALFTSFEREIASFPI
                     RSVTFQTERIFLENHPDFASNWGLIEDEETETWLGKDRRPYPLANVSHLEVLLADSSY
                     QDQISQLKFQAFSEEHESREVVDRYVAEALKDPESRLYILLKDGQVIGTCTVDLSTNT
                     NYFYGLAILEPERGKGYGSYLAKSLVNQLIEQNDKEFQIAVEDSNVGAKRLYEKIGFV
                     KQTQVVYLNEKGARDSEV"
     gene            35006..36349
                     /locus_tag="VQ865_000878"
     CDS             35006..36349
                     /locus_tag="VQ865_000878"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002916477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HET3135239.1"
                     /translation="MIKIYDTMSRDLREFVPIEDGKIKMYVCGPTVYNYIHVGNARST
                     VAFDTIRRYFEYRGYKVAYISNFTDVDDKIINRAREEGITPQEVADKYIAAFREDVTA
                     LGVKPATRHPRVVEFMADIIRFVEDLIEKGFAYESQGDVYFRVEKSHNYAKLANKTLE
                     DLELGASGRTDEETARKENPVDFALWKSSKPGEISWDSPWGPGRPGWHIECSVMSTEI
                     LGDTIDIHGGGADLEFPHHTNEIAQSEAKTGKAFANYWMHNGFVNIDNVKMSKSLGNF
                     ITVHDALKTLDGQVLRFFFATQHYRKPINFTEKAVRDAETNLKYLKNTYEQPFTGNVD
                     AQELQNFKDKFVAAMDEDFNAANGITVVFEMAKWINSGNYDASVKQALADMLEIFGIV
                     FVEEVLDAEIEDLIQKRQEARANRDFETADQIRDQLVTQGIKLLDTKDGVRWTRD"
     gene            36342..36728
                     /locus_tag="VQ865_000879"
     CDS             36342..36728
                     /locus_tag="VQ865_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HET3135240.1"
                     /translation="MIDVNLINGIALAFEGDAVYSMYIRRHLILKGMTKPNKLHQEAT
                     KYVSAKAQARLIALMLEEQVLTEKEEEIYKRGRNTNSHTKAKNADVVTYRMSTGFEAV
                     MGYLHMTENLERLESLVSWCIQKVEG"
     gene            36732..37616
                     /locus_tag="VQ865_000880"
     CDS             36732..37616
                     /locus_tag="VQ865_000880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PucR family transcriptional regulator"
                     /protein_id="HET3135241.1"
                     /translation="MREKELQDWFPEARISDQPVEKEGYLTLPLASQQWILLEEAGLS
                     EREKQLVALLTQQEQARSLNPWYSYLVEGKGQAPQVFKKIQLVYCHLSYFQQENLASW
                     LDMMRTLFPNCQTVLQVGSQDYVFVLQQDKYTYVRDILSDTIEAVEYDFGLRLSIMLG
                     QVWSQTGHQALSDLIKAERDLFKTWWRQGHQGVHTFSQLYLWSMGERLVDLKPIKECL
                     HQMILDQDQIQEIILSLWENSAVLTKTAQQLYLHRNSLQYKIDKWEELTGLQLKELTD
                     LTLCYQLILGSLSTIVGL"
     gene            37753..38187
                     /locus_tag="VQ865_000881"
                     /pseudo
     CDS             37753..38187
                     /locus_tag="VQ865_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817843.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            38495..38665
                     /locus_tag="VQ865_000882"
                     /pseudo
     CDS             38495..38665
                     /locus_tag="VQ865_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
BASE COUNT        11926 a         6681 c         8269 g        11865 t
ORIGIN      
        1 attattcttc atctggtgtg aggatcatcg ggatgatgat cggttcacgt tcggtatttt
       61 catagaggaa ggggcgaata gcgttgacaa tggcaccatt gacagattgc acgctagcat
      121 ccttattttt cagtgcgata cgaatggcat tgaagaggat acgctggctt tggcgaatca
      181 agtcgccaga ctctctcatg tagacaaagc ctcggctgag gatgtctgga ccagatagaa
      241 tcatctgcga tttgaagtca acagttgcga ctgccagaac gacaccgtct tcagatagat
      301 cgcgacgatc tttgaggaca gctgcgccaa tttcaccgat acgatttcca tcgacataga
      361 tatcttgggc gttgaaatga cctgcgatac gagctgagtc agcagtaagg gcaagcacat
      421 cgccattgct catgataaag atattgtcct tctcaacacc agtatccact gctagtccag
      481 cgtggacttt ttgcatgcgg tattcaccgt ggacaggcat gaagtatttt ggcttaatca
      541 agcggagcat gagtttttgc tcttgctgac caccgtgtcc agatgtatgg atattgttca
      601 ctttaccgtg gataacttcg acaccagctt cagaaataat gttaatcagc ttgttgacgc
      661 tagtagtgtt tccagggatg ggactagaag agaagataac ggtatcgcct ggttggagtt
      721 gtacctgacg gtgggttccg ttggcgatac gagagagggc tgccataggt tcaccttgac
      781 tacctgtaca gaggatcaga atctcacctg caggatagtc tttgatttca tttggctcaa
      841 taaaggttcc cttaggagct ttgatgtagc caagatcgat tccgttgaca atggcctttt
      901 ccatagagcg accaaagacc gcaatcttgc gcccagtctt aacagcagct tccgttgctt
      961 gttggagacg gaagatattt gaggcgaagg atgcaaagat gatacgtccc tcgatacctt
     1021 ggataatctt catgatggac tggccgacaa ccttttcaga gttggtaaag gttggaacct
     1081 cagcattggt cgagtcagag agcaagcaaa gcactccatc ttcacctagg gctgccatac
     1141 ggtgcaagtc cgcaggttct ccaactggag taaagtcgaa cttaaagtca cctgtacaga
     1201 tgattttccc ttgaggagta tggatgacaa ttcccaaagg ttctggaata gagtgagtcg
     1261 ttctaaagaa agttgccttg agatttttaa aggtcaactc ggtgttgtgg ttgatttcgt
     1321 aaagtttggc gttgcgcaag aggccgtgtt cttcgagttt cccacggatc aaagccaagg
     1381 caagcggtcc agcataaata gggacatttg cttgcttgag taggaacgga atcccaccaa
     1441 tgtggtcctc gtgtccgtgt gtgattaaaa cagccttgac gcggtcgata ttgtctacga
     1501 tgtaagagta gtcaggaatg acatagtcga taccaagcaa gtcatcttct gggaatttaa
     1561 tcccagcatc gacgatgata atctcgtctt ggtattcaat tccgtaagtg tttttcccga
     1621 tttctcctag accaccgatg gcaaaaacgc cgacttcttc aggtttaaga gtgtaggcca
     1681 tattagaact ccgtaatttt gaaggcgcca gtttcttttt cgtaatcgag caatttgtca
     1741 gacaagagtt cgatatattc gatattgtac tctgggcgat tttcttcgac aagttggcga
     1801 gcagcgatac gaccctcaag ttctgagctg gcatcgatgt ctaggtaaag cgcgcgtgtt
     1861 gtttcacgac gtgggctacg ttcttttgtt tcttgataaa aaactttgta aatcatatag
     1921 ttcctttcta tttacaggtc agcttattcc aaacttttag cagagatttg cttgatttca
     1981 ttccattttg tgtctagatt gaccttgatt cgttacaatt atttcaatta taccacaaaa
     2041 tgaaaaatta gtaaaagacg gaaacgagaa agttagggga cgatttcttt ggtaagcgtt
     2101 tgcaaaaaca aagaaaatgt attatgttga taacggaagt gaaatttatt gcttgtcata
     2161 attccatata gattttaagt caaggaggtt gccctatgta taacttattt gcttttgcta
     2221 tcggagttcg tttgctagct tttatcgttt ttgttgcttg cgtttatgga ggaaatcttc
     2281 tatttgccaa actggaacga tgacaaacca agttcttgag gaaaattacc tttgtgactc
     2341 tctactcgct ttttctcctc ctcgtgacct atgtcgtttg gtttgtattt tactttggat
     2401 tgccctgctt atgctggggt tttttgtttg gggatgtaga gatagtagat ttacgacacg
     2461 aaaattccac cccatctatc aagatgaggt ggtctttgca tttttctaac atgacatgac
     2521 aatggaattt tcaaagctta ttatttttat gggagtcatt gttctgctca aaaatagagt
     2581 tgaagcataa aaataaaaca atacaaacag ataaatcgaa tggtaaaggg atagtagtaa
     2641 tgttcaaatc attgagaatg ctgagcaaac tgtaagagat gaagacaata aaatttatcc
     2701 ttctaaaaat gtgtttctta tctagcatga cttaccaaac tttttacgaa ggtcttttcc
     2761 aatggtataa cctgccataa ataaagcgat accaacacct acaccaaagc cacccttgat
     2821 ttcttgcaat tccttattag aaatttcacg atagttgttc aaatttttca tcatattaat
     2881 ctcctcctaa aaaataacca gctgccaaac cagaacctat aagtgctgtt ccacctgcaa
     2941 tagctttcca agatactgct actccaaaga taaccaaggg agcgagaccg ccatcaatat
     3001 ctgataattc attttcagat aaggataaaa attgattgtc aagaatgtca aaatttgtca
     3061 ttgaattttc ctcctttttt cttgttcact tttatattcg gaaaagaaaa ggaaaagtga
     3121 gcattttttt aaattatttt tagttaagtg agggcactct tgtctggggg caaagaaaat
     3181 tcccatgtgc cagcttttgt agtataatag taagcagaca aaaagatagg aatgtgttat
     3241 gaaagtatta gcttttgata cgtccagcaa ggctctttct ctcgctattt tagaggataa
     3301 gcagattctt gccgagatga cgattaatat taagaaaaat cacagtatta ccctcatgcc
     3361 tgccatcgat tttttgatgg caagtttgga ctggacaccc aaggatttgg accgaatcgt
     3421 ggtggctgaa gggccaggta gctacacagg cttgcgaatt gcggtagcca ctgccaagac
     3481 tttggctcat actctgaaca tcgagttagt tggtatgtct agcctcttgg ctctggtacc
     3541 ctaccaacaa gaaggcttgt tcgtctcttt gatggatgcg cgtcgcaaca atgtttatgc
     3601 aggattttat gaaaatgcta aacccgtcat gccagaagct cacttaccct ttgagcgagt
     3661 gattgagtta atcaagggtg ctagtcaggt tacctttgtc ggagaagttg gcccctttgt
     3721 tgagcagatt caagaatact tgccaaggac taatttcaaa gaaaccttgc caaatgcagc
     3781 taatctagct ctatgggcct gggacaagga agcagactcc ttgcatgatt ttgtgccgaa
     3841 ctacctcaag cgtgtcgaag ctgaggaaaa ctggctcaag aatcacaccg agtctggcga
     3901 gtcttacatt aaacgcttat gatagaaatc aaacgaatcc aaaaacatcc tgacttggct
     3961 caagccatct acgctgttat gatagctgtt tacccagtca gtccttggac gctggaacaa
     4021 atccaagcag acctgtccca agaccagact tggtatgctt tggcttatga tggggcagaa
     4081 gtgattggat ttctagctgt gcaggagaat ctttttgaag cagaagtcct gcaaatcgct
     4141 gtcaaaggag cttatcagag tcaggggatt gcgtcagcct tgtttgctca attgccgaca
     4201 gacaaggaaa ttttcctcga agtcagacag tcaaatcaac gagcgcaagc attttacaag
     4261 aaagaaaaga tggcagttat cgctgagcga aaggcctact accatgaccc agtcgaggac
     4321 gccattatca tgaagagaga aatagatgaa ggatagatat attttagcat ttgagacatc
     4381 ctgtgatgag accagtgtcg ccgtcttgaa aaacgacgat gagctcttgt ccaatgtcat
     4441 tgctagtcaa attgagagtc acaaacgttt tggtggcgta gtgcccgaag tagccagtcg
     4501 tcaccatgtc gaggtcatta cagcctgtat cgaggaggca ttggcagaag cagggattac
     4561 cgaagaggac gtgacagctg ttgcggttac ctacggacca ggcttggtcg gagccttgct
     4621 agttggtttg tcagctgcca aggcctttgc ttgggctcac ggacttccac tgattcctgt
     4681 taatcacatg gctgggcacc tcatggcagc tcagagtgtg gagcctttgg agtttccctt
     4741 gctagccctt ttagtcagtg gtgggcacac agagttggtc tatgtttctg aggctggcga
     4801 ttacaagatt gttggggaga cacgagacga tgcagttggg gaggcttatg acaaggtcgg
     4861 tcgtgtcatg ggcttgacct atcctgcagg tcgtgagatt gacgatctgg ctcatcaggg
     4921 gcaggatatt tatgatttcc cccgtgccat gattaaggaa gataatctgg agttctcctt
     4981 ctcaggtttg aaatctgcct ttatcaatct tcatcacaat gccgagcaaa agggagaaag
     5041 cctgtctaca gaagatttgt gtgcttcctt ccaagcagca gttatggaca ttctcatggc
     5101 aaaaactaag aaggctttgg agaaatatcc tgttaaaacc ctagttgtgg caggtggtgt
     5161 ggcagccaat aaaggtctca gagaacgcct agcagccgaa atcacagatg tcaaggttat
     5221 catcccccct ctgcgactct gcggagacaa tgcaggtatg attgcctatg ccagcgtcag
     5281 cgagtggaac aaagaaaact tcgcaggctg ggacctcaat gccaaaccaa gtcttgcctt
     5341 tgataccatg gaataaagag tggctctttg tcaagtgtag tgggtaggcg aaaagctaca
     5401 atctggagag tacgaaattc gtactctctt ttttgatgtt caaagtcatc aaaatccgtt
     5461 ttttaaaatt gttaaagttc cggaaaccaa aggctttgcg cttgataacc ttaatcaaat
     5521 tattggtcgc ttcaagttta gcgttggaat aaggcagctt aagtgcgttg ataatcttat
     5581 ctctatccct taaaaaagtc caaaagaccg tttgaaaaag cggatgaacc gttggcagtt
     5641 cttgctcaat caatccaaag aaatggtcgg cattcttctc ttgaaaatga aagagcagga
     5701 gttgatagag ttcgtagtga acctgtaatc cctcagagta agaaagcagc ttatctcgta
     5761 cttcccgatg ggttaagtgc attcgaaacg tgggctgata gaatcgtttc tgacagagct
     5821 tgaagctatc ctggtgtagt aaatcagtcc agtggactga tttagcccga gcctagaaac
     5881 gaaaaagcga gggttccaaa agcgcttgag cgcccgatac tccaaggatt ttcggtcaaa
     5941 ttggttcatg atttggattc gtactcggtt catagctcgg ctcagatgtt ggacaatgtg
     6001 gaagcggtca agaacaatct tcgcctttgg aaagagttgc ttagcgagcc gataataagg
     6061 gctgtacatg tccatggtga tgacctcgac cagctcccga acctctctct gatagcgttg
     6121 gaaatggttt cgaatcaccg catgagttcg tccgtctaaa attgcgagga tggatttgga
     6181 ctcaaaatct tgggcaatga agctcatttt gctctttttg aagctatact catcccaact
     6241 cataactttt ggcaacttgg tccaatcggt ttcaaactta aattccctca gttttcggat
     6301 gacggtggaa gttgagcccg ccaatctgtg ggcaatctca gtcatagact gcttttcaag
     6361 gaggagctga gcgatttttt gtctcaccat gttggaaatc tggcaatttt tcttgacaat
     6421 ggatgtttga gaaacgacca ccttaaggca attcttgcac tgaaagcggc gctttttgag
     6481 atgcagtacc gtgggtaaac cctgacagtc gagaagcgga attttagagg ctttctggaa
     6541 gtcgtatttg atcatcttcc cttgacaatg aggacaagga ggagcggggg aatccaactt
     6601 tgcctgaacg actagatggg tttggtattt cagaacagac aagattttga tatttttgtc
     6661 ttccaatccg agcaaatctg tggtattctt aagttgttcc atatgaaccc tttctaatga
     6721 gttggttaga cgcttttcat tataggtcat atggggcttt ttttctacaa gaaacgaccc
     6781 tataattcct ggggtgggat tacccactac agaaattata gagccaaagc attccaaagt
     6841 cttgtctgac tctggaatgt tttctgttca cagttgtttt gtaactgcct aataagtaac
     6901 cgcgctataa cgaggtatct accgagattg tcaattctcc agtatactgt tataaaaaac
     6961 aaaactggag gattttttta tgtccccccc atcgtcccat cgactgttcc gtagctgccc
     7021 aataacggag tataatcagc tgaaacaaga ataggacaaa agtgcctcaa gaaaagcatc
     7081 gtaatttgac aatattattc tgagatgttt ttgatgtaag cccatatttt ctcaatggga
     7141 ttatactcgg gtgaataggt aggaagtggt aacagtctat gccctgctcc ttacacatgt
     7201 tcattctgtg aaaccttgca ttgtccataa tgataaggga tggtgtatct aaagtaggta
     7261 gtaagaattt ttggaagcaa gcttcgaaaa agtcactcgt catcgtatct ttataggtca
     7321 tcggagccat agtatattga aacaaaaaag ggcattagta cttctataac agtatcgcaa
     7381 tctctggtgt gcgttgtctc gatcttaatt caaataatta tatcttcttc cagagagact
     7441 aactgcctgc tcaaggctcg atcatattcg agataaaaat aggtctcaac ccctgtctca
     7501 taaatataaa taggagtcag gtagcttaag tgattcaatt ctttaaggaa ccgatttact
     7561 ttttctgggt cttgttcgca gtaggtacgg ctctttttta gactatatcc catagccttt
     7621 agagcgtaat gaatagttgt tggaggacag ttgaattcag cagctatttc agtcaaataa
     7681 gcatcgggat gagtttcaat atagattttt aatttatctc tatcaatttt ttcaattaat
     7741 agtggaagtt tttttgaagt tagtgtattg aaacgttttt atacagtgct aaaatttgaa
     7801 gtgtagtgca gatgtatttg taatagtatt atagcaattc tttggagaag gtcgagacaa
     7861 gataaaatag gtatctttga gatataagca tgatttacta taaaattatt gagttattca
     7921 taaaaatttc tctatcaaat atcataatgc gtcgtttaag gagatggtta caatgcaata
     7981 tagttgtgga aaaataaata ttaatatccc tgatggatat ggagacatta aggatatagt
     8041 gttttcggct catattatag ttaggtataa taatggacat tgtggaggta tagatccgca
     8101 tataattgga ctttgtaaaa agcagatcag aaggatgtct ctatatccta ttttgataat
     8161 cgtatctaga gattcaaagg ttattgatga ttataaaaat ttagatattg cctatgttga
     8221 ttgtactcaa tgttcaaata attttgaaac tgccttacac gttaaaaata ttttaaaatt
     8281 attaaaaatc caacttatac actgtcatgg ctactcaact aattattttt tatatatgtt
     8341 aaaaaaactt gacaagaatg gatttggaaa ggttaagaca gtgataacat gccatggatg
     8401 ggttgaatat aacttaaaaa agaaattctt gacttatttt gatttttgga catattctat
     8461 gggagatgct tttatttgtg tatctgaaac tatgaaaaaa agattggaga gtataataaa
     8521 aaaataagaa gatagttgca ataaataacg gaattaatgt atcaaatagc gatttagatg
     8581 tagtaggtgt tcaagacttt aaaaaagaat tttgtattcc aaataacaaa aaatcatttg
     8641 ttatgttgga aggttggatc cagaaaaaag gccggataga ttccttgaat ttgcagaaaa
     8701 attattttta gtcagagaag atgtgatttt tattatggct ggaaatggta gtatgtgggc
     8761 tgctttgaaa gaaaaaattt gctatttgaa atgtagagat aatttcaggt tacttggtga
     8821 aatctatcca gtactatagt ttaccaaata tcggatttat tgtatattcc ttctgataca
     8881 gaaggaatat ctatgtgtgt tttagagtca atgtcacaag gaactccggt tttagctagt
     8941 aatgttggcg ggttaagtga aattattgaa catagggttg atggattttt atttgagaag
     9001 gaagatgttg agggagtgtg tgcttgtgct aattttttac tcaatgattc tgagtatttg
     9061 aaatatgtag gtgagaatag taaatcaaaa ataagaaaac atttttctgt gcaaaaaatg
     9121 tttgtagaaa ccatgagagt atatgatgaa ttattagaga agagtagtca tggataggaa
     9181 tatagatcaa gaattagtaa gtattataat accaacacat aataggtatg aatctctgat
     9241 tagagctgtg aaaagttgtt tacatcaaag ttataaaaat atcgaagtta taattattga
     9301 tgataattat agtaatgtaa atttaagaaa taaaattatc catcaatttg gctataccaa
     9361 tcatagaatt aagttaattt taagtaatga agatttaggt gcaactaatg ccagaaacat
     9421 aggtatcaaa aattctagag gtaagtatat atcattttta gacgatgatg atgaatatat
     9481 gccagatcga attttaaagt tgatggcttg ttttaaaaag agtagaatga agaatttagc
     9541 tttagtttat agttatggaa taataattta tccaaatggt acacgagaag aggagaagac
     9601 cgattttgtt ggaaatccct tgtttgttca aatggttcac aatatagcag gtacgtcatt
     9661 ttggttgtgt aaaaaagagg tgctagaatt aattaatggt tttgagaaaa tagattcaca
     9721 tcaggacggt gttgttttat taaaactact tgctcaagga taccaaattg atatagtgcg
     9781 agaattcttg gtgaattact acgctcacag taaagaaaac ggtatcactg gagtgacaca
     9841 aaaaacaatt aatgcagatg aagaatatta taattactgt aggaaatatt ttaatttatt
     9901 gagtttcaac gagagaatat tggttacaaa gaaatattat tctttaaaca taaagcggtt
     9961 actatttaat aggagacaaa tgcaaggctt taaaagtaat caagaaggca agagaagaaa
    10021 aaatttttaa cgaatttctt ttttaaaata tatgttatta tatcattttg gttttttcta
    10081 ttgtatatat gacaactatg ttcaattaaa atttagaaag tgagaaacta ttgtgtatac
    10141 tattataaaa tcaaatataa aaaaatttag tttattaacg atatttattg ttgctggtca
    10201 attattgcta atttatgcag caactattaa tgctctggtg ttgaatgaat taattgcgat
    10261 gaatttagag cggtttttga aattgtcaat ctaccaaatg attgtctggt gtgggataat
    10321 attccttgac tgggtagtga aaaattatca ggttgaagtg atccaagagt ttaatctaga
    10381 gattcgaaat agagttgcca cagacatctc taactctacc tatcaagaat ttcatagtaa
    10441 atcatcagga acatatcttt cgtggctaaa taatgatgtt cagactttaa atgatcaggc
    10501 ttttaaacaa ctttttttag taataaaagg aatttctggt actatatttg cagttgtgac
    10561 tcttaatcac tatcattggt cattgactgt agccaccttg ttttcattaa tgattatgct
    10621 acttgtacca aaaatctttg catcgaaaat gcgagaagtt agtctaaatt taactaacca
    10681 aaatgaagct tttttaaaat ctagtgagac tatattgaat ggatttgatg tgttagcgtc
    10741 cttgaatctt ttatatgtat tgcctaagaa aattaaagaa gcaggaattt tattaaagat
    10801 ggttatacaa agaaagacaa ctgtagaaac gttagcaggc gctattagct tctttctcaa
    10861 tatttttttt cagatatctc tcgttttttt aacaggctat cttgcaataa aaggaatagt
    10921 gaaaattggt actattgaag caataggagc actaacaggt gttattttta cagcgctagg
    10981 tgaattagga ggtcaattat cctctattat tggtacgaag cctatttttt taaaattgta
    11041 ttcaattaat ccaattgagt caaataaaat gaatgatatc gaaccaaatg aggtgaatag
    11101 agattttccg ttatatgaag caaaaaatat ttgctataag tatggagata aagaaatatt
    11161 aaaaaactta aatttttgtt ttcaacgtaa tgaaaagtat ttaattttag gtgaaagtgg
    11221 aagcgggaaa tctacattat taaaattatt gaatggcttt ttgagagatt atagtggaga
    11281 attgcgattc tgcggggatg atataaaaaa aacctcctat ttaaatatgg tttcgaatgt
    11341 tctatatgta gatcaaaaag cttatttgtt tgaaggtacg attagagata atattttatt
    11401 ggaagaaaat tatactgatg aagaaatact acagtcttta gagcaagttg gtttgagtgt
    11461 aaaagatttt cctaataaca ttttagatta ttatgttggt gatgatggga gattactgtc
    11521 aggagggcag aaacaaaaaa ttactttagc tagagggcta attagaaata agaaaatagt
    11581 attaattgac gagggaactt ctgctatcga taggagaact tcgttagcga ttgaacgtaa
    11641 gatattagat agagaggatt tgactgtcat tattgttacc catgctccgc atccggaact
    11701 taaacaatat tttactaaga tatatcaatt tccaaaggat tttatttaag aatatagggg
    11761 agggaaacat gagattctat tgtgaagctt atgaggtaat tactgaagag aaaaaagtat
    11821 actttaatga tattgagtta gaagttaagt attcctctgt cgaagaattg tttataatat
    11881 gtgagaaatt attagataag aaaaaagtat cattttttta tgtatatgag aaacccttaa
    11941 ggtatctgtt atttgactat atatttctac tagttctagc taaaaaaata tcccaatctt
    12001 agatggagtt tccaataagc aagttgatcc aacgttgctg catcactttt ctttggaaat
    12061 tgaaaagaat tttatcgatt tttgctataa aaatatggat ctcatcctaa aaactcaaag
    12121 tatatctttg tgtcatagag aagagcttat tattgtagat gtttcagatg actctaaatt
    12181 tggtgttttt tacaagcgtt ttagaacact ggttgataaa aataacggaa aatatgtttg
    12241 tgtttataat ttcagtcgtg tttcagatat actgcaaaac tggaaaaatt attgcaatcg
    12301 aaaattttcg gttacgttta ctgaaagcca atttgaatta tttaagcttt tatataatca
    12361 aaaaaatttt aaaacaattt cgttgctatt tggaaaaaaa ttgttgctgg aggaattatc
    12421 tattatagcg atcttactaa tatagaatac ttttgtattt tttggtggga tagtatgttt
    12481 gggaaagatt ctattggaaa atacgtatat gtagaagaga ttagtagatg tcatttttta
    12541 gatagaaatt attctttttg ttatggttta caagattata aaagtaaact tattaaatat
    12601 tttttagaat agttaatcta ttcgagagag ataaagaaat atggaaaata ctttattgaa
    12661 tatcacagga agcttcgata tggaaactag gaatctaatt agttattctt taactgatat
    12721 ctttgaaaca gataaaataa gaattgaact tcttggagaa atttattata aaaatataaa
    12781 gttggaattg catgaattcg ctggattgta taagatttat ggaattagct taataaagaa
    12841 tattaccgga atgtttttaa ttataatttt tgatacgaag acaaaagaat taaaaatttt
    12901 tcaagatata acgacttcat actttaattt atactatact gtttatggag gtgtgttcta
    12961 tatatagtac atctttaaag aaagtgatga agttatctca tgttcccgtt accttaaata
    13021 acaaaaaaat acaagaattt atgagaaatg gatttatttt agattcaaat actttagtaa
    13081 ccgaaattaa taaattagaa tatttctctt acatttctgt aaataatact cttcgtatat
    13141 gtggtattga ttataatgat tcaaacaatt ttactaaaga acaagtatta aagaattggg
    13201 actctatgct acgtgaatct atattaagag tgtatagtga agcaggagag gctaatatta
    13261 cactatcatc tggttttgat tcaaattata tattatatac attagcgaat tatacgaatt
    13321 cttcaattaa tgcattttgc ataggaggag aaaaaggaat taatgagatt cctgaagtaa
    13381 ctaaaattgc aaaattttat ggtataaatt tattagttga tactgtaatg agcccaagat
    13441 ttagaatatt ttcccgatat agtatggaga ttggaaggaa gtctctttga atgtggtgtc
    13501 atactgcagt actatttagg caggttgttg ttccaaaaag ggaacacaag tattctttgt
    13561 ggcgagtcag cggatgaaat aatgactttt aagtatcatt ctgtgaacta caatcaattt
    13621 tgtaatgata aacagaagtc agtatatttt agttattccg actatccatt ttatgttaca
    13681 aattcaattg ttttaaagaa aaatagccta cttttgcata gttttggcat tcatcctaga
    13741 tatccatata aaatgtctga gattgttgaa atgtctaaaa aaatatcaga tctaaacgat
    13801 aaaaaagaat ttcacaaaaa gaactgtgag ttgaggtttc aagatagtgt tcttgataac
    13861 ataaatagtg tcccgggtac aactcattta tttagttgtt taaatattca aacattagta
    13921 aaaattattt tatatatttt tcgatacaac agttgtatga aaatatttaa ttttagagat
    13981 aaagagctta tcttttttaa taagattgta aatgggctga tacaaaatat tgaggagaat
    14041 ttagaggatg atattgaaag gatattgaaa tatttatata tatgtttatt taacgaaata
    14101 ttcattatta agaataaggt gaattttttt gatgatgtgg aatttaatca gacacttagt
    14161 gagtttttag ataaattgta gagggaatgg ttatgagtga caatactaag tatatctttt
    14221 tatctccaca tttagatgac gcaatttttt cctgtggtga ttatatttca aaattaactt
    14281 cagaaggaga aattgtactt gttattacta tattttctgg ttaccctttg agccaacagc
    14341 tacagccctc tgctaagcaa tttcataagt tgtgtaacct tgggaaatat ccgattgaag
    14401 aaaggaagaa agaagacagg ttagcttgtg aacgtctaca atgtgatttt agacacttat
    14461 cgtactatga atgtctctat aggaaagata gaaatggcaa ttttctatac cgtcatatct
    14521 atagtaaatt aaaaaatgag gacacattaa agaatgatat cataaaagag ctgttaatgc
    14581 atttagacga caaatgtgtc gtatattgtc cgctttcact tggtgaccat gttgatcatg
    14641 tttttgtgaa tagtattgga agggcgcttg aatttatgcg ttataaagta atatattatg
    14701 aggacttccc atatgtaagt gatagtagta tggttagtta tatgggaaaa actaaagaat
    14761 taaaaatgta tcaagaggaa cttgatgaaa aacattatat tgatagaata tcatcaatat
    14821 tgtgctataa atctcagatt ttgataatct ggaaatcagt tgaaaaactt ttaaacaata
    14881 ttaaagagtt gtatttaagg aatggggcag cttattctat tagattttgg attaagaaat
    14941 aaggaagtag ttttatgaat atagcagtaa ttggtttggg gcatgttggg ctggcctacg
    15001 cgttactatt tgcatctaaa tataaagttg ttgcatatga tatagattct gtaaaaataa
    15061 ataatttaaa aaagggcact cttccatcta aaaatgaaga gcttatgaag tttttttgcg
    15121 agaataactt aaatattact ttttttgata cattttctga aattaaaaat aatattgatt
    15181 attatattat tgcgcttccg acagattatg atgagaaaat tggtagtttt aatacatatg
    15241 aaatcgaaca aacggtatcg aagattctga gggtaaaacc taatggaaag attattttaa
    15301 agtcaacagt tccgatcggc ttttcaaaca aattaaaaag gctgtttgat acaaaaaata
    15361 tcatttttgt ccctgaattt ttgagagaag gttgttctat atatgataat ttatatccaa
    15421 gtcgcatagt tgttggagat gagacagttg aaggaagaaa aattgcagag ttgttccttt
    15481 cgattagtac tcatagtact gccaatatta aaaatgttat gttagtttct cctactgaag
    15541 cagaagcaat taagcttttt tctaacacat tcttagctct ccgtgttgct ttttttaatg
    15601 aactagattc ttttgctgag aggagaagtt taaatgctga agttgtaata aaaggtgttt
    15661 gtttagatcc aagaattgga aatttttata ataatccttc ttttggattt ggaggatatt
    15721 gtcttcccaa agatactaaa caattaaaaa aagaatttat agaaataaat gccccagtga
    15781 tagaagcgat tgatatttca aacacaaata gaaaacagtt catagttaaa caaatattgg
    15841 aacgaaagcc aaagatagta ggaatatata aattggggat gaaatataat tcagataatt
    15901 acaaagagtc agctatttta agtataatta atgaactatt gattgtcggt ataaaaattt
    15961 tagtatatga accaaattta aacgttagta tagataacgt aatttttgaa aagaattttg
    16021 aactatttat aaaacaaagt gatctaattg ttgcaaatag atgggatagg gaccttgaag
    16081 cttataaaga taaagtttac acaaggggga tctggataag agattaacta ttgatattaa
    16141 aaaggcaata atttataaaa tttgtacaaa aaaatgttaa attttcacat tttcatagta
    16201 tactgtttaa tagaaagtag gttctttgta accgctccat tataaaatcc tttcactctt
    16261 ccggtatact attaggaaaa acataactgg aggatatttt gagctcacac ctcatcgttc
    16321 cagtggctgt tccccaagct cgtgtactgc ccaaaaaagt tagacattct atttagaacg
    16381 aggattgagt tctgtattgt acaaggctcg gtccttttag agtcagctta aggctggctt
    16441 tttcaatcac caaagtgtca gaatgttttg acaaatgaac acaaataatg atataatatg
    16501 caaaagctag gaggtggtag gatgattgaa aaaatggaac tgggggaatt ttacaaggaa
    16561 ttgcgcttgg cgagaaagct caagcagtca gatgtggctt gtgctggact aacagcctct
    16621 cagttgtcca agtttgaact aggacagtct atgctgtctg cagacaagct gatcctagcc
    16681 atccaaggga tcaatatgaa ttttgatgag tttgggcaca aactcaacaa ctatcaagaa
    16741 tctccacata tgcgaattgg tagaagggtt gtggattgct tttcccatca ggatatagct
    16801 gctttagagc agctattgga ggaagtcgat caagaacaga tggcgcagac ctatcgtcgt
    16861 ttgaatgcca ttgtgattaa aaatgcactc cattccttag ataaaagcta cccgctaaca
    16921 gaggaggata gcgagttttt gactacctac ctctacgcta ttgagtcttg gacctggttt
    16981 gaactctatc ttttttgcaa tactatgccc ttcttgagca atcaagatct gatcttttta
    17041 tcaacctcct tactcgaaaa atccaaggaa tttaaagagt tagtacacaa tcgatggtat
    17101 atgaaaagtg gttatcttaa tatcatctca gaacttatgg agcgcaagct attttcttat
    17161 attccaatct ttgaagctga gctggagcgc atgctccgtc catacgatgt ttttgaaaaa
    17221 gtattgtggc agtttttaaa gaaaatgcag atttttcttc aaaccaaagg aagcaatcaa
    17281 aaagagattg aacactttat ccaatctctg caagtattag aaaatccaca attgacagcc
    17341 ctttttgaat tgcgtttgca gcaatacaaa gagcttatcg attagttaga aatgggaaaa
    17401 agataataat atcagcaacg atcgtcaata atgttaaaac ttgtttcttc atattacttc
    17461 cctcctcatt agtaataact ttattatacc agggaaataa tcaaatctac caaaatcgca
    17521 aatctgaaat ttctataaga aaaaatatca aatatgcgat tttctaaaat aagccaattt
    17581 ccgtgttata ctgtccttgt aaaacatttg aagcaaatcc taggtcgcag aagtggttta
    17641 caaatgaaga taattgaagg agtgtaaaag atgttaaatt tacaatttgc agaaacaatg
    17701 gaattgacag aagctgagtt gcaagatgtt agaggaggca acctcgtaaa ttctatggga
    17761 ggtggtggaa gaagtggtat atctggttgg ggcgtcccag gaatttaccc tggttggggc
    17821 aatcaaggga tgagtcctaa tcgtggagct tttgattgga ctatagattt agcagatgga
    17881 ttgtttggcc gccgtagaag ataggctctt ataggagata ataggatgaa gaaaatgaaa
    17941 gaagtgaaat ttcacctagc aactggcttg ttgattttga cttattacct catttttaat
    18001 gtcacatcag acttagattt tatggttgct ttgtctgata atatgtacta tgtgttccaa
    18061 gttttattgg tacttattct gggaactata gctacaattg cttttgtcaa aagtgaacat
    18121 tggaaagagt gtggtcgttt ccagtttcgt tggtcttacc tgggtgtttt ccttctttct
    18181 tttttcttat tgttcgtgtg ggcaaatcta acaacctata tctttcctcg tacccagaat
    18241 ggaagtacag tcgtagaagt agccaccagt ttaacaggaa ttagctattt tgttacgcga
    18301 atactttata ctagtattat cgcacctgta tcagaagagg ttgtttgtcg tggtcttttg
    18361 atgacaagtt tatctaaagt taatagatac tatcttgatg ttcttgtttc cgctgccata
    18421 tttggcgcta tgcatgtttt gcagtatggt tggataacga cagatttcat aaagtatttt
    18481 ggaatgggct tgatattttg tatgatgttt cgctacaccc gatccatcta ttgggctata
    18541 gctctgcatg cttcatggaa tagcttctta ctcattgtta ctttattggt atttggatat
    18601 tagaaaggtg atatatgaaa aagataatct cacaccgcta ctttattata gtttttctac
    18661 tagttattgc tgaccagaag ttcagtgttt tagttttacg cagcgacctt gttgctgggc
    18721 tatctgactt tgcctattat ctgtcggata tgatgttgaa ttttcttgtg gttttatttg
    18781 ctcttattgc tatgatttgg tcggggaaat ggcagaaaat caatagtaga aagtttaaag
    18841 gatcctatct tttctattcc ttcctagctc tgcttgcttt tgttgcttgg aattttgtca
    18901 ccttttttct tttcccacct actcgaaatg aaatttctta tcaacatgct gctcctactt
    18961 ttacaggagc tacggcattt ttgatgtatt ttttttatcc tgtgattgca ggtcccattt
    19021 ttgaagacat gatttatcgt ggattagtga tgactgctct ggaaaaagga aagaaatggg
    19081 ggctagatgt acttggttcc gctgttttat ttggggtctc gcacattagt aatcacggtt
    19141 gggtcttgac agactttgtc ttctatatgg gtggaggtct tatatttgca gtcttattta
    19201 gaatgacaaa gtcaatttat tggcctattg gactgcatat agtctacaat ggtattggtc
    19261 agcttttgat gttactgtaa ttttggttgt tagtagtatc gcggtctatt cttggggaaa
    19321 gattcccatt tgaatttaaa aaggagttgt aatgaaagta tttcttcaaa atagagattt
    19381 taggcaatta actatcaacc agtggatttc aacgcttggg gatacgattt tttatctggc
    19441 cttcctgaat tatgtggcag atgcgtcttt tgcccctttg gcgattttac ttatcacgat
    19501 ttcagaaacc cttccccaag ttctacaaat ctttctggga gttttggcgg attttcaaca
    19561 tcatcgtgtc ttgaaataca cagtcattag ttttacaaaa tttttgcttt actctatagt
    19621 gtccctatcg ctttcagggc agtctttttc cttgttgcta gtaaccttta tttgtctgat
    19681 taacctcttg tctgacacat tgagttattt ttcaggcgcc atgctcactc cgattttcat
    19741 tagaattatt gggcaagatc atctggcaga agctattgga tttaaacagt caactgttag
    19801 tttagtgaaa acaatcagta atatcctagg aggagtctta ctaggtattc tatccatcca
    19861 gtttatttcc ttactgaacg ctcttacctt tttaatcgca tttttaggta tcctcttcat
    19921 aaaaactgac ctcttgaaag tagaaaaaac gattagctat caagaaggac tctctgtaaa
    19981 atccttttgc cagcatttgc tccaatcatc gaaattgata tggaatatga ataaggtgct
    20041 cttggttttg tttattatct ctactagtca agcagtgata aatgttacag ttcctgtctc
    20101 tactctattt ttgaggaatc aacccttttt gaatttacaa acaggtcaat ctcttgcctt
    20161 gctatccact tttgaactgt cagccctgat tgtcggaagc cttgtaagtg gctatctgca
    20221 acataccatt tccataaaaa cagctctcta tgcctcactt gtcatccagt tgcttcttct
    20281 agtaggattt gccacagttc gttttgactg gattctcatc tttagtacct tggatgcctt
    20341 tttcgcaggt gttctctctc ctagattgca agaactcgtc tttaaacaaa tacctgagga
    20401 gtcaatggga gcagttcaat cttctatcag tgccattacg gttgttttac ctagcttatt
    20461 tacaatatct ttggtaacca ttgctactag ctttggaact ctggcagtta gctttgtttt
    20521 attgctattt cttctagttg cctttgttat gcttctgaat attcgtgaaa gtatttagtg
    20581 gagaatttct ataatatatg tttgagactg gattgccagt ctttttatga tggtcaaaat
    20641 caacagactt ttttctcttt tctgaatgtg ttatagtaga ctgaatctaa aatagtacga
    20701 aacaattgct aaaacattta tagaaattaa ttttactttc ccaatcgatt tgttttcatc
    20761 ttatttcaat ccgctataaa gttagataag aataagctaa caagcagaag taagataggt
    20821 cttgcaagaa tggtaaaaat ctgataaact aagtggtaat tgaatagaaa tctgaaagac
    20881 tagtagccca agggaagtat atcagggagg agagccgtga ctgcaagctc tctatatgaa
    20941 agctgggtga attcacttgc gcatggattt agaaatgaag gtctgacttg tcagatgaaa
    21001 acggatggta ccgcgtgtca acgctccgag tggagttttt ggcatgtggt tttcttttta
    21061 tctacgagag actgatggag gaaatatgtc aactattgaa gaacaattaa aagcgcttcg
    21121 cgaagaaacg ctgactagct tgaagcagat tactgctgga aatgaaaaag agatgcaaga
    21181 tttgcgtgtc tctgtccttg gtaaaaaggg ttcgctcact gaaatcctca aagggatgaa
    21241 agatgtttct gctgagatgc gtccaatcat cgggaaacac gtcaatgaag ctcgtgatgt
    21301 cttgacagct gcttttgaag aaacagctaa gctcttggaa gaaaagaaag tcgcggctca
    21361 actggctagc gagagtatcg atgtgacgct tccaggtcgt ccagttgcga ctggtcaccg
    21421 tcacgttttg acacaaacca gtgaagaaat cgaagatatc ttcatcggta tgggttatca
    21481 agtcgtggat ggttttgaag tggagcaaga ctactataac tttgaacgta tgaaccttcc
    21541 aaaagaccac ccagctcgtg atatgcagga tactttctat atcactgaag aaatcttgct
    21601 ccgtacccac acgtctccag ttcaggcgcg tgctatggat gcccatgatt tttctaaagg
    21661 tcctttgaag atgatctcgc cagggcgtgt cttccgtcgc gatacggacg atgcgaccca
    21721 cagtcaccaa ttccaccaaa tcgaaggctt ggtagttggg aaaaatatct ctatggctga
    21781 tcttcaagga acgcttcagt tgattgtcca aaaaatgttt ggtgaagagc gtcaaattcg
    21841 tttgcgtcca tcttacttcc cattcacaga gccatctgtt gaggtggatg tttcttgctt
    21901 caagtgtggt ggagaaggct gtaacgtatg taagaaaaca ggttggatcg aaattatggg
    21961 agccggtatg gttcacccac gtgtccttga aatgagtggt atcgatgcga ctgtatactc
    22021 tggttttgcc tttggtcttg gacaagagcg tgtagctatg ctccgttatg gaatcaacga
    22081 tatccgtgga ttctaccaag gagatgtccg cttctcagaa cagtttaaat aatgattaga
    22141 aaagtagaaa tggcagatgt tgaggtgttg gctaaaattg ccaaacaagc ctttcgtgaa
    22201 acctttgcgt atgataatac ggaagagcag ttacaggaat actttgaaga ggcttatagt
    22261 ctgaaaactt tgtcaactga gttgggaaat cctgactctg aaacctattt cattatgcat
    22321 gaggaggaga tagctggttt tctcaaagtc aactggggaa gtgctcaaac tgagagagaa
    22381 ttagaggacg cttttgaaat tcaacgcctc tatgtgctac aaaaattcca aggatttgga
    22441 ctaggtaagc aactgtttga attcgcactt gaacttgcta caaaaaatag tttttcttgg
    22501 gcttggctag gtgtttggga gcataataca aaagctcaag cgttttataa tcgatatggt
    22561 tttgaaaaat ttagccaaca tcattttatg gttggtcaaa aagtagatac ggattggtta
    22621 ctgagaaaga aattaaggta agaagaggat tcttctattg aaatgatagg aaaggaaaag
    22681 aaccagtgtg gcaatggtca ttctggagaa ctaaattatg cttatatctt ataaatggtt
    22741 aaaagaattg gtggacattg atgtgccatc acaagagttg gctgaaaaaa tgtcaactac
    22801 aggaatcgag gtcgaaggtg tcgaatcacc agctgctggt ctctcaaaaa ttgtcgtcgg
    22861 tgaggtcttg tcttgcgaag atgtgccaga gactcacctc catgtttgtc aggttaacgt
    22921 tggcgaagaa gagcgtcaga tcgtttgtgg tgccccaaat gtgcgtgctg ggatcaaggt
    22981 catggtggct cttccaggag ctcgtatcgc tgataactac aaaatcaaaa aaggaaaaat
    23041 ccgtggtttg gagtcacttg gaatgatctg ttcacttggt gaattgggaa tttctgactc
    23101 agttgtgcct aaggaattcg cagatggcat ccaaatcttg cctgaagatg ccgtgccagg
    23161 tgaggaagtc ttttcttacc tagacttgga tgatgaaatc atcgaacttt ccatcacacc
    23221 aaaccgtgca gatgcccttt ctatgtgtgg agtggctcac gaagtggcag ccatctatga
    23281 caaggcagtc aactttaaag aatttactct aacagaaact aatgaagctg cggcagatgc
    23341 cctttctgtc agcattgaga cagacaaggc gccttactat gcagctcgta tcttggacaa
    23401 tgtgaccatc gcaccaagtc cacaatggtt gcaaaacctt ctcatgaacg aaggaatccg
    23461 tcccatcaat aacgtagtgg acgtgaccaa ctacatcctg ctctattttg gtcaaccaat
    23521 gcatgccttt gacttggata actttgaagg gactgacatc cgtgtgcgtg aagcgcgtgc
    23581 tggtgaaaaa ttggtgacct tggacggtga agaacgtgac ttggacgtga atgacctagt
    23641 catcactgtc gcagacaagc cagtagccct tgcaggtgtc atgggtggtc aagcaacaga
    23701 aatctctgaa aaatctagtc gtgttgtcct tgaagctgct gttttcaatg gcaaatctat
    23761 ccgtaagaca agtggtcgcc tgaaccttcg ttctgagtca tcttctcgct ttgaaaaagg
    23821 aattaatgtg gcaacagtta atgaagccct tgatgcggca gctagcctga ttgcggaact
    23881 tgcaggtgcg acggtgcgta agggcatcgt ttcagcgggt gagcttgata cttcagatgt
    23941 agaagtttct tcaacccttg ctgatgttaa ccgtgtcctc ggaactgagc tgtcttatgc
    24001 tgatgtagaa gacgtcttcc gtcgtcttgg ctttggtctt tctggaaatg cagacagctt
    24061 tacagtcaga gtcccacgtc gtcgttggga tatcacaatc gaagctgacc tctttgaaga
    24121 aattgctcgt atctatggtt atgaccgctt gccaactagt ctaccaaaag acgatggtac
    24181 agcaggtgaa ttgacagcca cacaaaaact ccgccgtcaa gttcgtacta ttgctgaagg
    24241 agcaggtttg acagaaatca tcacctatac tctaacaact cctgaaaaag cagttgagtt
    24301 tacggctcaa ccaagtaacc ttacggaact catgtggcca atgactgtgg atcgttcagt
    24361 cctccgtcaa aatatgattt caggtatcct tgataccgtt gcctacaacg tggctcgtaa
    24421 gaataaaaac ttggcccttt acgagattgg aaaagtcttt gaacaaacag gtaatccaaa
    24481 agaagaactt ccaaatgaaa tcaacagttt tgcctttgcc ttgacaggct tggttgctga
    24541 aaaagatttc caaacagcag cagttccagt tgatttcttc tatgctaagg gaatccttga
    24601 agccctattt actcgtttgg gactccaagt aacctataca gcaacatctg aaatcgctag
    24661 ccttcatcca ggtcgtacag ccgtgatttc actcggtgac caagttcttg gtttccttgg
    24721 ccaagtgcat ccagtcactg ccaaggctta cgatattcca gaaacgtatg tggctgagct
    24781 taacctttca gctatcgaag ctgcgcttca gccagcgact ccatttgtag aaatcaccaa
    24841 attcccggca gtcagccgtg acgttgccct tctcctcaag gcagaagtga ctcatcaaga
    24901 agttgtagat gctatccaag ctgccggcgt gaaacgtttg acagatatca aactctttga
    24961 cgtcttctca ggtgagaaat tgggacttgg tatgaagtca atggcttata gcttgacctt
    25021 ccaaaatcca gaagatagct taacggacga agaagtcgca cgctatatgg aaaaaatcca
    25081 agcatcgctc gaagaaaaag tcaatgcaga agtgcgttaa acgatagtat gatacaaatt
    25141 ccccctctag tttatgaaca ctagaggggt gattttatat aaaataatta aaatgtgatt
    25201 tctgtaaaaa tacatctatg atcagagttt tgaaaactta caatgtctaa atctttaaca
    25261 tagtagtggt ttttaggcaa taaaatatga tctattgttg cattaaaaag ttttggactt
    25321 tggctattcc aagttcctct ttcaaaaggt ggcagtacat ttaatgcgtc cctatgagag
    25381 cttatttttg caagtgctcc atgacgcata gttgcattaa aatcacctgc aataatagcc
    25441 tttggatatt ttgaagccaa ttgattatga atgatgttta agtcttgctt ccagatttcc
    25501 attaaacctg gcagaggagg agcagtatgc aaggcaatga tatctggtat attttgtttt
    25561 ctcgaatgta atacaattgt cccgaaccgt gttgtatgaa aagttttagc ttctgtatag
    25621 aaaccataac ttttcttgac aatcacagtc acaggagcta ttccactatt ggtaggtgga
    25681 gaagtgaaaa tatcatagtt ggccatagaa agtccaactt gatgaaacaa tagtttgatt
    25741 ctctggtttt cttgctcacc tctgatattg gtagctagtt cagggaatat agccatatcg
    25801 gcgtcaaaat ggctaaaaat tcgctcaata tgttgtgctt ctatttgatt agcgacgttc
    25861 caagttacta attttaaggt tttagtctta tttgatgcag aagaaagggt tttatctgtt
    25921 ccgaataata gtaatatgag cgatagtaag agcaaaatgc cagagtaaaa ccgtatttgt
    25981 ttatttttct tgtaaaaaga taggaaaaaa aataagaaac ttaaaatagc agccatagtt
    26041 gcagtagcta aggggaaggc ataaatctgt gccaagatag gttgggtaga tagccaaatg
    26101 ttaagattag aagatgggaa aaaagaataa gttatgatag ggataacaaa gagaatgacc
    26161 gaaagggcag agagaaatgt tttaatcatt gtgtgagtac ctcaatttgc aatggttgct
    26221 cggagctaat gtgactttgt gactttactt gattgatatt ctttttcttg tcttcctcat
    26281 agattaagta caacccaagt aaaaaaagtc caatttaaga ttgaaatgat taaaaggcac
    26341 agagatgcaa gacaattata ctacaaaagg taaacatttg acaatcgata gccgtcgctt
    26401 aatcgaaaga tggaaaaaag aaggaaaatc aaatagagaa gttgcctctc tacttggaaa
    26461 agctcctcaa actatccaca ctgaaatcaa gcgtgggaca gtccgaaaat gtcttggaaa
    26521 agggcgcttc aaagaggttt attctgccga ctacgctcaa cagtcttatg aaaacaatcg
    26581 caagcgctcg gtcaagaaat caagcttgac caaggaacta aaggaaaaga ttctccacta
    26641 tacataacca aaaattttcg cctgaaatga tggttatggc taaaggggtt aacgtgggaa
    26701 tttcaaccat ttactattgg attcatcgtg gaaaattggg gttaagcaag caggatctgc
    26761 tttatcctag aaaaggaaaa tcgcttaaga aataggctag caccaacttt aaacccgctg
    26821 gtcaatctat cgaatcataa ttcgctcatt tttttaaaaa tacatagacg taaaagaaag
    26881 agggttaagt gatgaagaat agtgctattg ggagtaattg gaaggatgtc catctgagct
    26941 ctttagcaag gaggaaatcc ttgaaagtga tatgcgagta gctatcatga gcgagttgat
    27001 tgaagccaga aataagcaag gaatcagtca gaaaaagcta gaggaactca gtggagtgag
    27061 tcagcctgtt atagctagga tggagacagg taagactagt ccacagttgg acacagtctt
    27121 aaaagtccta gctagtctag gaaagatact agcagtcgtc cgacttgaac aggggaaaag
    27181 ttgactagaa tcagttatag tcttttctaa taacaagcca tagtcactta taagaattac
    27241 taataacgcg tttgagcatt ctaactaaaa tacagctaaa aacaagttat aaaagggatt
    27301 tgaggcatgt gtctcaagtc tttttctttt gtctaaaata gaggtatagt ttcaaactat
    27361 atcaaagcct aattttttac aattatacag atgctttctt ttctgttaag atagtttcaa
    27421 caacaaattt tggaggacac atcatgtcaa ctacaatcat cggtttccct cgtttgggcg
    27481 aattccgtga attaaaattt acaactgaaa aatactttag aaaagaaatc tcagaagaag
    27541 aacttttagc agcagcaaaa gacttgcgtg ctaaacactg gaacattgtc aaagaaaaag
    27601 gcatcactga aattccatca aatgactttt ctcactatga taacttccta gatgcggctt
    27661 tccttttcaa cgtggtgcct gcatccgttc aaaacttgga cttgtctgac cttgagcgct
    27721 acttcgcttt gggacgtggt taccagggag aaaaagggga cgttcgcgcc cttccaatga
    27781 agaaatggtt caacactaac taccactaca tcgttcctaa atttgaaaaa gacactcaag
    27841 taaaattggc tggtcacaag attttcgatg agttccaaga agcaaaagaa cttggattga
    27901 acactcgtcc tgttcttgta ggtccattca ctttccttca attgtcagac tttgaagaag
    27961 gcgtgaaagc agacgacttc gtagatagct tagtggctgc ttaccaagaa gtttttgcta
    28021 aattggctga acttggtgcg actcgcatcc aattggatga agcggctctt gtaaaagact
    28081 tgacagctga agaaaaagct ctcttcttga acctttacaa caaactcttg gctgacaaaa
    28141 aaggtcttga agtcttgctt caaacttatt tcggtgatgt tcgtgacgta tacgctgacc
    28201 ttgtaaactt gccagtagat gctatcggtc ttgactttgt tgaaggtaag aaaactcttg
    28261 aactcgttaa aggtggcttc ccagctgaca agactctcta tgtaggtatt gtcaatggta
    28321 aaaacatctg gcgcaacaac tacgaaaaga gcttggctgt tcttgagcaa atcccagctg
    28381 aaaacatcgt tttgacaagc tcttgctcac ttcttcatgt gccatttaca actgctaatg
    28441 aagaatttga accagcactc ttgaaccact ttgcctttgc agttgaaaaa ttggatgaaa
    28501 tccgtgactt ggatgctatc cgcaatggtc aaggttcaga agctcttgca gccaacaaag
    28561 aactctttgc gactgagcgt gttggtgaaa atgctgaact tcgtgcgcgt atcgctggct
    28621 tgacagacgc agactacact cgtttgccag cctttgcaga acgtgaagct atccaagaag
    28681 aagctttcaa acttccagct cttccaacaa caacgattgg ttcattccct caaacaaaag
    28741 aagttcgtgc caaacgtttg gcttaccgta aaggtgaatt gtctcaaaaa gagtacgatg
    28801 ctttccttgc tgaaacgatt gacgaatgga tcaagtggca agaagatatt gactttgatg
    28861 tccttgttca cggtgaattt gagcgtaatg acatggttga gtacttcggt caaaacttgt
    28921 caggatactt cttctctaaa aatggatggg tacaatcata cggtatgcgt ggggtaaaac
    28981 caccaatcat ctggggtgat gtcactcgtc ttaaccctat cactgttaaa tggtctagct
    29041 atgcacaaag tcgtacaaac aaacctgtta aaggtatgtt gactggacct gttaccatcc
    29101 ttaactggtc attcccacgt gaagacatct ctatcaagga ttctactctt caaatcgccc
    29161 ttgctatcaa ggatgaagtg cttgaccttg aagctgctgg tgtgaaaatc atccaaattg
    29221 atgaggctgc tcttcgtgaa aaattgccac tccgtcgtag tgactggtac gaagattacc
    29281 ttgactgggc aattcctgcc ttccgcttgg tacactcaac agtagcgtca gacacacaaa
    29341 tccacactca catgtgttac tcagaattta cagatatcat cccagctatc gataacatgg
    29401 atgcagacgt tatttccttt gaagccagcc gttcaaacct tgaaatcttg gacgaactca
    29461 aagcgaaaaa cttccaaaca gaagtgggac ctggggttta cgatatccac tcacctcgtg
    29521 taccaaacga aggcgaaatc gacaacacaa tcgaagccat ccttgctaaa gtgccaagca
    29581 agaaagtttg gatcaaccct gactgtggtt tgaaaacacg tggtatccca gaaacaaaag
    29641 aaagcttgat ccgccttgtt gaagcagcta aagctgcgcg tgagaaattg taagattgga
    29701 tttctctcca tacagtggtt gttcaaaaag aaatcaacta gaaaaggtta ttacatatgt
    29761 cacgccaaac accgtcactc tcatttgaag tgttccctcc aaacccagcc gtgggtaatg
    29821 gtaacattat ttcagccttg caggatatgc aggagttggc tccccatttt atcagtgtaa
    29881 ctgccagcaa taataaattt aatatcaagg aaacgacggt tcgtttggct gactttatcc
    29941 aaaatgactt ggcgattccg accattgccc acttgccagc tatttatcta actaaggaca
    30001 aggttgctga aactattgtt gacttggaca aagttggggt tcagaaaatc ttggctcttc
    30061 gtggggatat tattccagac gtagaaccac aaaaggattt ccgctatgca accgacttga
    30121 ttgagtttat caaggaacaa gcccctcact ttgatattat tggagcttgc tatccagaag
    30181 agcatccaga ttcgccaaat cagatttcag atattcaaaa tcttaagaag aaagtggatg
    30241 caggctgttc gagcctcgta actcagctct tctttgacaa tgagcgcttc tatgattttc
    30301 aggacaagtg tatcttggct gggattgatg ttcccattca tgcaggaatt atgccaattc
    30361 tgaatcgaaa tcaggctctc cgactcttga agacttgtga gaatatccat cttccacgca
    30421 aatttaaagc catcttagac aagtatgagc atgaccctga gtcgctcaga gcagcaggac
    30481 ttgcctatgc agtggaccaa atcgtggact tggtaactca ggatgttgcc ggtgtgcatc
    30541 tctatacgat gaataatgct gatacagcaa aatacatcca tcaagcaacc catgccttgt
    30601 ttaatcacca gtctctagga taataaaagc aaaccattct tctcaggtga ggggaatggt
    30661 tcctttttaa tggtaaagac ctcacttttt aagaaaaata tgataaaata aattctgtac
    30721 gtacttgata caaagatgaa ggtattaaat aatacaatgc atttaaactg taagatttaa
    30781 cgacacgagt gagtcaaatc gatgttattt gacgagagag ttagtaaagc atttagctaa
    30841 tcgcccgata gcgattagcg tgaaagcttt agatacttta gtattaaacc tttctaatga
    30901 tgtatcttga aaactgaact tgcctacaac tctgtggaaa aagataaatc tccctaggag
    30961 tagtcgctcc gtcgttcgat ttcctatctt cctttgagtt gcttgacggc ttggtatctt
    31021 gagtaattga acacggccga aaagctgtgt aaaaaagata aactgtcttg tcttcatcga
    31081 agacttcgtc agtttcctat ttttactttg cttttgacgt ccttggtatc ttgatctttg
    31141 taggcaaggc gtataatttc atcaatcaaa aggggattaa aatggcaaaa caagtgtttc
    31201 aaacgacttt tgcgggtcgt gagttaattg tagagactgg tcaggttgct aagcaagcaa
    31261 atggatctgt tgtcgtacgt tacggtgagt caactgtctt gactgctgcc gttatgtcta
    31321 agaaaatggc aactggggat ttcttcccac tccaagtcaa ctacgaagaa aaaatgtatg
    31381 cggctgggaa gtttcctggt ggctttatga aacgtgaagg acgtccttca acagatgcga
    31441 ccttgacagc gcgtttgatt gaccgtccga ttcgtcctat gtttgcggaa ggtttccgta
    31501 atgaagtcca agtcatcaat acagtgcttt cttatgatga aaatgcatct gcaccaatgg
    31561 ctgctatgtt tggttcatct ttggcactgt ctatttcaga tattccattt gacggaccaa
    31621 ttgctggggt acaagtggga tatgtagatg gccaaatcat catcaaccca agtcaagaac
    31681 aagcagagca atctcttctt gaattgacag tagctggaac caagcacgct atcaacatgg
    31741 tagagtctgg tgccaaagaa ttgtcagaag aaatcatgtt ggaagcgctt cttaaagggc
    31801 acgaagctgt caaagaattg attaccttcc aagaagaaat cgttgctgct gtcggtaaag
    31861 aaaaagcaga agtggaattg cttcacgtgg atgctgaatt gcaagctgaa atcattgcag
    31921 cctacaacag tgacctccaa aaggcagttc aagtagaaga gaaattggcc cgtgaagctg
    31981 caactcaagc agtgaaagac caagtgactg ccgtttacga agaaaaatat gcgaaccacg
    32041 aagaatttga ccgtattatg cgtgatgtgg ctgaaatctt ggaacaaatg gaacacgcag
    32101 aagtgcgacg tttaattaca gaagacaagg tgcgtcctga tggtcgtaag gtcgatgaaa
    32161 tccgtccttt ggatgcggtt gttgacttcc ttcctcgtgt acatggttca ggtctcttta
    32221 ctcgtgggca aactcaagct ctttcagtct tgaccttggc tccgatggga gaaactcaaa
    32281 tcattgatgg tttggatcca gagtacaaga aacgctttat gcaccactat aacttccctc
    32341 aatattctgt aggggaaaca ggtcgttacg gtgcgccagg tcgtcgtgaa atcggtcacg
    32401 gtgctcttgg tgagcgtgct cttgctcaag tcttgccaag cttggaagaa ttcccatacg
    32461 ctatccgtct agtagcagaa gttttggaat caaacggttc ttcatctcaa gcttctatct
    32521 gtgcgggaac tcttgccctt atggctggtg gtgtgccaat caaggcgcca gtagctggta
    32581 ttgctatggg acttatctca gatggaaata actacacagt attgacagat atccaaggtt
    32641 tggaagatca ctttggagat atggacttca aggttgcagg tactcgtgat gggattacag
    32701 cccttcaaat ggatatcaag attcaaggga ttactgcaga aatcttgacg gaggctcttg
    32761 ctcaagccaa gaaagcgcgt tttgaaatcc ttgatgtcat tgaagcaacc attccagaag
    32821 ttcgtccaga attggctcca actgctccga aaattgatac gatcaagatt gatgtggaca
    32881 agattaagat tgtcatcggt aagggtggag aaaccatcga caagattatc gctgaaacag
    32941 gtgttaagat tgatatagac gaagaaggaa atgtgtctat ctactctagt gaccaagatg
    33001 ctattaaccg tgccaaagaa attattgctg gtttggttcg tgaagccaaa gtggatgaag
    33061 tttaccgtgc taaagtcgtt cgtatcgaga aatttggtgc ctttgttaac ctctttgata
    33121 agacagatgc ccttgttcat atctctgaga tggcttggac tcgtaccaat cgtgtagagg
    33181 atttggtaga aatcggggat gaagttgatg ttaaggttat caagattgat gaaaaaggcc
    33241 gtatcgatgc ctctatgaag gctcttctac ctcgtccgcc aaaacctgag catgatgaaa
    33301 aaggtgaaaa gtctgagcgc cctcaccgcc cacgtcatca aaaggatcac aaacctaaga
    33361 aagaatttac agaaacacca aaagattcag aataagaaaa ggagaaatgt atggggtggt
    33421 ggcgcgaaac cattgatatt gtaaaagaaa atgatccagc ggcccgcacc actttggagg
    33481 ttttgctgac ttatccaggt gtcaaggcct tggcggccca ccgtctctcg cattttctct
    33541 ggaagcacgg cttcaaacta ttagctcgta tgtacagtca gttttggcgc ttttggactc
    33601 agattgagat tcatccagga gcccagattg attcaggtgt ttttattgac catggttctg
    33661 gtctggtgat tggagagaca gcgattgttg aaaaaggcgt tcttctctat cacggagtga
    33721 ctctcggggg aacagggaaa gactgtggca aacgccatcc gactgtacga aagggagccc
    33781 tcatatcagc ccatgcccaa gttatcgggc ctgtggaaat tggtgaaaat gccaaggtcg
    33841 gtgctgcagc agttgtcgta gcagatgtac ctagtgacgt gacggtggtc ggtattccgg
    33901 ccaagattgt ccgtcttcat ggtaagaaag atgagcctgt cattcacgaa gtcgaagaaa
    33961 aacgagagta ttatgtcaat aaactcgagc aggctaaaga tgccagtcac agatcgtctg
    34021 gtttgtagag gatacctata tgattcaagc aagaaacaag ttaagccaag aggagctatc
    34081 tgaagcgaaa aaagtaatta actgttgcca aaactatgac ggtacctatc gcgatcccta
    34141 tctctctaac atgcttaatt ttgacccaaa catgcccgcc tttttccttt attatgaaaa
    34201 aggcgaactt gttggtttat taactgtcta tgcagatgac caagatgtag aagtaacgat
    34261 actggttcat ccaggtcatc gccgtcaggg gattgcgcgt gcattgttta ctagttttga
    34321 gagagaaata gcttctttcc ccattcggtc agtcactttt cagacagaac gtattttttt
    34381 agagaatcat cctgactttg ccagtaactg gggactaatc gaggatgaag agacagaaac
    34441 ttggttaggt aaggatagaa gaccttatcc gttagcaaat gtttcccatc ttgaagtttt
    34501 gttagcagat agttcgtatc aggatcaaat tagtcaatta aaatttcagg cattttcaga
    34561 ggaacatgaa tcgagagaag ttgtggatag atatgtcgct gaagctctga aggatccaga
    34621 aagtcgctta tatattttat taaaagacgg tcaggttatt gggacttgta cggttgattt
    34681 atcgactaat acgaattact tctacggttt agcaatattg gaacctgaac gtggaaaagg
    34741 ctatggaagc tacttagcaa aatccctcgt caaccaacta attgagcaaa atgacaagga
    34801 atttcagatt gcagtggaag atagcaatgt aggtgccaaa cgtttgtatg aaaaaattgg
    34861 ctttgtcaaa cagactcagg tggtttatct gaatgagaaa ggagcaaggg attccgaagt
    34921 gtagagatat tcggactgaa atttacttga acttttagtg atgaaactaa ttgttcttgg
    34981 atttcagctt tcctgattat gatttatgat taaaatctat gacaccatgt ctcgtgattt
    35041 gcgagaattt gtcccgattg aggacggcaa gatcaagatg tatgtttgtg ggccaacggt
    35101 gtacaactat atccacgtgg gaaacgcccg ttcgacggta gcttttgata cgattcgtcg
    35161 ctattttgag taccgtgggt ataaggttgc ctatatttcc aattttacag atgtggatga
    35221 taagattatc aaccgtgcca gggaagaagg catcacgcct caggaggttg cggataagta
    35281 catcgctgcc tttcgtgagg atgtgacggc cttgggcgtg aaacctgcga ctcgccatcc
    35341 gcgtgtagtg gagtttatgg cagacatcat ccgttttgtg gaagacttga tcgagaaagg
    35401 ctttgcctat gagagtcaag gggatgtcta tttccgtgta gaaaaatccc acaactatgc
    35461 taaattggct aataaaacct tggaagattt ggagctaggt gcttcaggtc gtaccgatga
    35521 agaaacggct cgtaaggaaa atcctgtaga ctttgctcta tggaaatctt ccaaaccagg
    35581 tgagatttct tgggatagtc cttggggacc tggacgtccg ggttggcata ttgagtgttc
    35641 agtcatgtcg acagagattt taggtgatac cattgatatc cacggtggtg gagctgacct
    35701 agagtttcca caccacacca atgaaattgc ccaatctgaa gctaaaacag gcaaggcttt
    35761 tgctaactac tggatgcaca atggctttgt caatatcgac aatgtcaaaa tgtctaagtc
    35821 cttgggtaac ttcattacgg tacacgatgc ccttaaaact cttgatgggc aagtacttcg
    35881 tttcttcttt gcgacccagc actaccgtaa gcctatcaac ttcacggaaa aggcagttcg
    35941 cgatgccgag accaatctca agtatctgaa gaatacttac gaacaaccat ttacaggaaa
    36001 cgtggatgcc caagagttac aaaactttaa agataagttt gtagcagcta tggatgaaga
    36061 ttttaatgct gccaacggta tcacagttgt ctttgaaatg gccaaatgga tcaactcagg
    36121 gaactatgat gcaagtgtca agcaagctct tgcagatatg ttagaaattt ttggaattgt
    36181 ctttgttgag gaagttttgg atgcagagat tgaagacttg attcaaaaac gccaagaggc
    36241 gcgtgccaat cgagactttg agacagcaga ccaaatccgt gaccaattgg ttactcaagg
    36301 aattaagctc cttgatacca aggatggagt gaggtggaca cgtgattgat gtcaatctca
    36361 ttaacgggat tgcgctagcc tttgaggggg atgcggtgta ttctatgtat attcgccgtc
    36421 acctcatcct caaaggtatg accaaaccca ataaactcca tcaagaagca accaagtatg
    36481 tgtcagccaa ggctcaggct cgcctgattg ctctcatgtt ggaggagcag gtcctaacgg
    36541 aaaaagaaga agaaatctac aaacgtggcc gcaataccaa tagccacaca aaggctaaaa
    36601 atgcagatgt cgtgacttat cgtatgtcca cgggatttga agcggttatg ggctatctcc
    36661 atatgactga gaatctggaa cgtcttgaga gtttggtttc atggtgcatc caaaaagtgg
    36721 agggctagaa catgagggaa aaagaactac aagactggtt tcctgaggct cggatttcag
    36781 accaaccagt agagaaagag ggctatctca cgctcccttt agcttctcag cagtggattt
    36841 tgctggagga agctgggctc agcgagcgtg aaaagcagtt ggttgccctt ttgacccagc
    36901 aggagcaggc tcgttcgcta aacccttggt attcctatct ggttgaaggc aagggacagg
    36961 caccgcaagt ttttaaaaag attcagttgg tttattgcca tctttcttat tttcagcagg
    37021 aaaatctggc ttcttggcta gatatgatgc ggactctttt tccgaattgt cagacagtgc
    37081 tacaggtcgg atctcaggat tatgttttcg tgcttcaaca agacaaatac acttatgtaa
    37141 gagatatttt aagtgatacg attgaagcgg ttgagtatga ctttggactt cgtctttcta
    37201 tcatgttggg tcaggtttgg tctcagacgg gacatcaagc cctatcagac ttaatcaaag
    37261 ctgagcggga tttgttcaag acatggtggc gtcagggtca ccaaggtgtt catacttttt
    37321 ctcagctcta tctttggagt atgggagaaa gactcgtgga cttgaagcca atcaaggaat
    37381 gtctacacca gatgattttg gatcaagatc agattcagga aatcattctc tctctttggg
    37441 aaaatagtgc tgttctcact aaaacagccc agcaactcta tctgcaccgc aattctctcc
    37501 aatacaagat tgataaatgg gaagagttga cagggcttca gttgaaagag ttgaccgacc
    37561 tgaccttgtg ttatcaattg attttaggtt ctttgtcaac tatagttggt ttgtaaagaa
    37621 gttaatattt ggagaagagg atggccatct tctccatttt tatgtgcaga gttatagtgg
    37681 cttgatgctg ggaaagtaca ctgtgactgc taaaacattc ctagaagttg ctttgatttc
    37741 cctaatctat ttatgtgaat tttatgttat tttactataa cagttgttgc taagctaaat
    37801 aatagtgggg aagtttattt agacgtaagc attgaagata atcagggagg tagtgggtat
    37861 aatttcagtt ctgtttcaag tagctcacaa acagctaaat atgaaggaac tggttataat
    37921 aacaattcat cattatatat aacgattgat aaaacgtctg atgcaacagc tcttttgaaa
    37981 ttaaagttga ataatgttga taatcaacct gctactgaag ttcctagttc aggaattact
    38041 gtaaaattaa atgctaaaga taatgctgga aactggacaa gtgcttcgaa taaaaaagaa
    38101 gtaacagtaa aaattgtttc tgctaaaccg acatatccag acaaaatttt agtgaaaaat
    38161 cctgataata taaaagatac agaaaaaaat gccattattg aaaaattgaa agaggcaaat
    38221 aaaaatcatc cagcaggagc tccaaccttt gctaaaggtg aaggagagca tgcaaatgat
    38281 attgtagcaa cttattcaga tggtacaact tattatgtac cgttaaatga tgtgacaaaa
    38341 tatgcgaggt agtggctgta ccactcactt attcacctcc ccgtgatttg tagtagtgat
    38401 aggctttctc actattatta taaaacaaaa taaagatcac aacacttttt cattctgtgt
    38461 tgtgccttga gtgaaacgaa aggaatgaat tataaatatg aaaagtatag tcactaacat
    38521 agatgagcgc ttgcgtactc gcctacgagt gattatctgg aagcaatgga agaagaaatc
    38581 gagacgatta tggggattgc ttaagttagg ggttcctaaa tggatagcag ataaggtatc
    38641 tggctggggc gagcactatc aattatatta aaatgaaata agaataggac gaatcgatca
    38701 gggaagtcaa atcgatttct aacaatattt tagaagtaga g
//
LOCUS       DAVBOG010000016        38411 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.016, whole genome shotgun sequence.
ACCESSION   DAVBOG010000016 DAVBOG010000000
VERSION     DAVBOG010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 38411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38411
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.016"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(56..1066)
                     /locus_tag="VQ865_000883"
     CDS             complement(56..1066)
                     /locus_tag="VQ865_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family putative sulfate export transporter"
                     /protein_id="HET3135242.1"
                     /translation="MSFLSKNGAGILVCLLISIVSWYLGGFFPVIGAPVFAIFMGMLL
                     HPFLSSYKQLDAGLTFSSKKLLQYAVILLGFGLNISQVFAVGQSSLPVILSTISIALI
                     VAYLFQRFFALDTKLATLIGVGSSICGGSAIAATAPVIHAKEKEVAQAISVIFFFNVL
                     AALIFPTLGTWLHLSNDGFALFAGTAVNDTSSVTATASAWDSLYQTNALESATIVKLT
                     RTLAIIPITIFLSYWQSREQKNKQGLQLKKVFPLFILYFILASLLTTLLTSLGVSSSF
                     FTPLKQLSKFLIIMAMSAIGLKTNLVAMVKSSGKSIVLGAVCWIAIILTSLGMQTLIG
                     IF"
     gene            1215..2384
                     /locus_tag="VQ865_000884"
     CDS             1215..2384
                     /locus_tag="VQ865_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3135243.1"
                     /translation="MDLTKRFNKQLDKIQVSLIRQFDQAISEIPGVLRLTLGEPDFTT
                     PDHVKEAAKRAIDQNQSYYTGMSGLLTLRQAASDFVKEKYQLDYAPENEILVTIGATE
                     ALSATLTAILEEGDKVLLPAPAYPGYEPIVNLVGAEIVEIDTTENGFVLTPEMLEKAI
                     LEQGDKLKVVILNYPANPTGITYSREQLETLAAVLRKYEIFVVCDEVYSELTYTGEAH
                     VSLGTMLRDQTIIINGLSKSHAMTGWRLGLIFAPATFTAQLIKSHQYLVTAANTMAQH
                     AAVEALTAGKNDAEPMKKEYIQRRDYIIEKMTALGFEIIKPDGAFYIFAKIPAGYNQD
                     SFAFLKDFAQKKAVAFIPGAAFGRYGEGYVRLSYAASMETIKEAMKRLEEYMREA"
     gene            2381..3151
                     /gene="recO"
                     /locus_tag="VQ865_000885"
     CDS             2381..3151
                     /gene="recO"
                     /locus_tag="VQ865_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000616164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HET3135244.1"
                     /translation="MIQSITSQGLVLYNRNFREDDKLVKIFTEQVGKRMFFVKHAGQS
                     KLAPVIQPLVLARFLLRINDDGLSYIEDYHEVMTFPKINSDLFVMAYATYVAALADAS
                     LQDNQQDAPLFAFLQKTLELMEAGLDYQVLTNIFEIQILTRFGISLNFNECVFCHRVG
                     QAFDFSFKYGACLCPEHYHEDKRRCHLNPNIPYLLNQFQAIDFETLETISLKPGIKQE
                     LRQFMDQLYEEYVGIHLKSKKFIDSLADWGQLLKEEKK"
     gene            3148..4140
                     /gene="plsX"
                     /locus_tag="VQ865_000886"
     CDS             3148..4140
                     /gene="plsX"
                     /locus_tag="VQ865_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000717456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HET3135245.1"
                     /translation="MKKIAVDAMGGDYAPQAIVEGVNQALSDFSDIEVQLYGDEAKIK
                     QYLTATERVSIIHTDEKIDSDDEPTRAIRNKKNASMVLAAKAVKDGEADAVLSAGNTG
                     ALLAAGFFIVGRIKNIDRPGLMSTLPTVDGKGFDMLDLGANAENTAQHLHQYAVLGSF
                     YAKNVRGIAQPRVGLLNNGTESSKGDPLRKETYELLVADESLNFIGNVEARDLMNGVA
                     DVVVADGFTGNAVLKSIEGTAMGIMGLLKTAITGGGLRAKLGALLLKDSLRGLKKQLN
                     YSDIGGAVLFGVKAPVVKTHGSSDAKAVYSTIRQIRTMLETDVVAQTAREFSGE"
     gene            4146..4379
                     /locus_tag="VQ865_000887"
     CDS             4146..4379
                     /locus_tag="VQ865_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HET3135246.1"
                     /translation="MTEKEIFDRIVTIIQERQGEDFVVTESLSLKDDLDADSVDLMEF
                     ILTLEDEFSIEISDEEIDQLQNVGDVVKIIQGK"
     gene            4425..4715
                     /locus_tag="VQ865_000888"
                     /pseudo
     CDS             4425..4715
                     /locus_tag="VQ865_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            4918..5148
                     /gene="blpU"
                     /locus_tag="VQ865_000889"
     CDS             4918..5148
                     /gene="blpU"
                     /locus_tag="VQ865_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpU"
                     /protein_id="HET3135247.1"
                     /translation="MNTKKMSQFEIMDTEMLACVEGGGCNWGDFAKAGVGGGAVRGLQ
                     LGIKTRTWQGAATGAAGGAILGGVAYAATCWW"
     gene            5863..8016
                     /locus_tag="VQ865_000890"
     CDS             5863..8016
                     /locus_tag="VQ865_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter"
                     /protein_id="HET3135248.1"
                     /translation="MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKT
                     TMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDLTFPFVAHVLKEGKLLHYYVVTG
                     QDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
                     LVKQRGLIANIVLATLLVTGINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYIL
                     QQILSYAQEYLLLVLGQRLSIDVILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSII
                     DALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTVIIFAFMKPFEKMNR
                     DTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQK
                     ALKKVAHLLLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQT
                     AQVANNRLNEVYLVASEFEEKKTVEDLSLMKGEMTFKQVHYKYGYGRDVLSDINLTVP
                     QGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYINYLPQQ
                     PYVFNGTILENLLLGAKEGTTQEDILRAVELAEIREDIERMPLNYQTELTSDGAGISG
                     GQRQRIALARALLTDAPVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAE
                     RTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS"
     gene            8029..9378
                     /locus_tag="VQ865_000891"
     CDS             8029..9378
                     /locus_tag="VQ865_000891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HET3135249.1"
                     /translation="MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKE
                     MSLSTRATVEPSRILANIQSTSNNRILVNHLEENKLVKKGDLLVQYQEGAEGVQAESY
                     ASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
                     ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSFYQSYK
                     SQGEENPQTKVQAVAQVEAQISQLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQ
                     HLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLHLNPETSDSSMVAEG
                     ALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSID
                     ATATKTEKGNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE"
     gene            9548..10255
                     /locus_tag="VQ865_000892"
     CDS             9548..10255
                     /locus_tag="VQ865_000892"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HET3135250.1"
                     /translation="MSKQLIYSGKAKDIYTTEDENLIISTYKDQATAFNGVKKEQIAG
                     KGVLNNQISSFIFEKLNAAGVATHFVEKLSDTEQLNKKVKIIPLEVVLRNYTAGSFSK
                     RFGVDEGIALETPIVEFYYKNDDLDDPFINDEHVKFLQIADDQQIAYLKEETRRINEL
                     LKVWFAEIGLKLIDFKLEFGFDKDGKIILADEFSPDNCRLWDADGNHMDKDVFRRGLG
                     ELTDVYEIVWEKLQELK"
     gene            10457..14182
                     /locus_tag="VQ865_000893"
     CDS             10457..14182
                     /locus_tag="VQ865_000893"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HET3135251.1"
                     /translation="MDKRIFVEKKADFQVKSESLVRELQHNLGLSSLKSIRIVQVYDV
                     FDLAEDLFAPAEKHIFSEQVTDHVLDEVSVQADLANYAFFAIESLPGQFDQRAASSQE
                     ALLLLGSSSDVTVNTAQLYLVNKDIDVTELEAVKNYLLNPVDSRFKDITTGIAKQEFS
                     ESDKTIPKLTFFESYTAEDFARYKAEQGMAMEVDDLLFIQDYFKSIGRVPTETELKVL
                     DTYWSDHCRHTTFETELKHIDFSASKFQKQLQSTYDKYIAMREELGRSEKPQTLMDMA
                     TIFGRYERANGRLDDMEVSDEINACSVEIEVDVDGVKEPWLLMFKNETHNHPTEIEPF
                     GGAATCIGGAIRDPLSGRSYVYQAMRISGAGDITAPISETRAGKLPQQVISKTAAHGY
                     SSYGNQIGLATTYVREYFHPGFVAKRMELGAVVGAAPKGNVVREKPEAGDVIILLGGK
                     TGRDGVGGATGSSKVQTVESVETAGAEVQKGNAIEERKIQRLFRNGNVTRLIKKSNDF
                     GAGGVCVAIGELADGLEIDLNKVPLKYQGLNGTEIAISESQERMAVVVRPEDVDAFVA
                     ECNKENIDAVVVATVTEKPNLVMNWNGETIVDLERRFLDTNGVRVVVDAKVVDKDVKL
                     PEERQTSAETLESDTLTVLSDLNHASQKGLQTVFDCSVGRSTVNHPLGGRYQLTPTEA
                     SVQKLPVQHGVTHTASVIAQGFNSYVAEWSPYHGAAYAVIEATARLVAAGANWSKARF
                     SYQEYFERMDKQAERFGQPVAALLGSIEAQIQLGLPSIGGKDSMSGTFEELTVPPTLV
                     AFGVTTADSRKVLSPEFKAVGENIYYIPGQALSAEIDFDLIKKNFAQFEASQADHKVT
                     SASAVKYGGVVESLALATFGNYIGAEVTLPELKTALTAQLGGFVFTSPEEIAGVEKIG
                     QTKADFTLTVNGVKLDGHKLDSAFQGTLEEVYPTEFTQAKELEEVPAVASDVVIKAKE
                     KVEKPVVYIPVFPGTNSEYDSAKAFEKEGAEVNLVPFVTLNEEAIVKSVETMVDNIDK
                     TNILFFAGGFSAADEPDGSAKFIVNILLNEKVRVAIDSFIARGGLIIGICNGFQALVK
                     SGLLPYGNFEDANSTSPTLFYNDANQHVAKMVETRIANTNSPWLAGVQVGDIHAIPVS
                     HGEGKFVVTAEEFAELRDNGQIFSQYVDFNGKPSMDSKYNPNGSVHAIEGITSKNGQI
                     IGKMGHSERYEDGLFQNIPGNKDQHLFASAVKHFTGK"
     gene            14275..15717
                     /locus_tag="VQ865_000894"
     CDS             14275..15717
                     /locus_tag="VQ865_000894"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HET3135252.1"
                     /translation="MTYEVKSLNEECGVFGIWGHPDAAKLTYFGLHSLQHRGQEGAGI
                     LSNDQGQLKRHRDMGLLSEVFRNPSNLDKLTGAGAIGHVRYATAGEASVDNIQPFLFR
                     FHDMQFGLAHNGNLTNAASLKKELEQRGAIFSATSDSEILAHLIRRSHNPSLMGKIKE
                     ALSLVKGGFAYILLFEDKLIAALDPNGFRPLSIGKMANGAVVVSSETCAFEVIGAEWI
                     CDLKPGEIVIIDDEGIQYDSYTDDTQLAICSMEYIYFARPDSNIHGVNVHTARKRMGA
                     QLAREFKHEADIVVGVPNSSLSAAMGFAEESGLPNEMGLIKNQYTQRTFIQPTQELRE
                     QGVRMKLSAVSGVVKGKRVVMVDDSIVRGTTSRRIVQLLKEAGATEVHVAIGSPALAY
                     PCFYGIDIQTRQELIAANHTVEETRQIIGADSLTYLSIDGLIESIGIETDAPNGGLCV
                     AYFDGDYPTPLYDYEEDYRRSLEEKTSFYK"
     gene            15754..16776
                     /locus_tag="VQ865_000895"
     CDS             15754..16776
                     /locus_tag="VQ865_000895"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HET3135253.1"
                     /translation="MTNKNAYAQSGVDVEAGYEVVERIKKHVARTESAGVMGALGGFG
                     GMFDLSKTGVKEPVLISGTDGVGTKLMLAIKYDKHDTIGQDCVAMCVNDIIAAGAEPL
                     YFLDYVATGKNEPAKLEQVVAGVAEGCVQAGAALIGGETAEMPGMYGEDDYDLAGFAV
                     GVAEKSQIIDGSKVVEGDVLLGLASSGIHSNGYSLVRRVFADYTGEEVLPELEGKKLK
                     EVLLEPTRIYVKAVLPLIKEELVNGIAHITGGGFIENVPRMFADDLAAEIDESKVPVL
                     PIFKALEKYGQIKHEEMFEIFNMGVGLMLAVSPENVERVKELLDEAVYEIGRIVKKEN
                     ESVIIK"
     gene            16773..17318
                     /gene="purN"
                     /locus_tag="VQ865_000896"
     CDS             16773..17318
                     /gene="purN"
                     /locus_tag="VQ865_000896"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HET3135254.1"
                     /translation="MKKIAVFASGNGSNFQVIAEEFPVEFVFSDHRDAYVLERAKQLG
                     VLSYAFELKEFESKADYEAALVELLEEHQIDLVCLAGYIKIVGPTLLSAYEGRIVNIH
                     PAYLPEFPGAHGIEDAWNAGVGQSGVTIHWVDSGVDTGQVIKQVRVPRLADDTIDRFE
                     ARIHEAEYRLYLEVVKALFTD"
     gene            17402..17911
                     /locus_tag="VQ865_000897"
     CDS             17402..17911
                     /locus_tag="VQ865_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000894002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3135255.1"
                     /translation="MLESKKTTRYVFYVYLMLLTWGILFKFETNPEFIAFFLAPRYIN
                     WIPFSEPLIVDGKIVFAEMLFNLISFIPLGVCFPLIKTNLSSLRIVGTGFLISLLFEC
                     LQYILAIGITDITDLTLNTLGVCVGLLIYQIFIRVFKSQTRKWINILGMLSLGFAYLV
                     LLLLHLIGV"
     gene            17936..19483
                     /gene="purH"
                     /locus_tag="VQ865_000898"
     CDS             17936..19483
                     /gene="purH"
                     /locus_tag="VQ865_000898"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006146083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HET3135256.1"
                     /translation="MTKRVLISVSDKAGIVEFAQELKKLGWEIISTGGTKVALDNAGV
                     DTIAIDDVTGFPEMMDGRVKTLHPNIHGGLLARRDLDSHLEAAKDNKIELIDLVVVNL
                     YPFKETILKPDVTYADAVENIDIGGPSMLRSAAKNHASVTVVVDPADYAVVLDELAAN
                     GETSYETRQRLAAKVFRHTAAYDALIAKYFTAQVGESKPEKLTLTYDLKQPMRYGENP
                     QQDADFYQKALPTDYSIASAKQLNGKELSFNNIRDADAAIRIIRDFKDSPTVVALKHM
                     NPCGIGQADDIETAWEYAYESDPVSIFGGIVVLNREVDAATAEKMHGVFLEIIIAPSY
                     TDEALAILINKKKNLRILALPFNAQEASEVEAEYTGVVGGLLVQNQDVVKESPADWQV
                     VTKRQPTETEATALEFAWKAIKYVKSNGIIVTNDHMTLGVGPGQTNRVASVRLAIDQA
                     KDRLDGAVLASDAFFPFADNVEEIAKAGIKAIIQPGGSVRDQESIEAADKYGLTMVFT
                     GVRHFRH"
     gene            19605..20867
                     /gene="purD"
                     /locus_tag="VQ865_000899"
     CDS             19605..20867
                     /gene="purD"
                     /locus_tag="VQ865_000899"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000772208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HET3135257.1"
                     /translation="MKLLVVGSGGREHAIAKKLLESKDVEKVFVAPGNDGMTLDGLEL
                     VNISISEHSKLIDFAKTNDVAWTFIGPDDALAAGIVDDFNQAGLKAFGPTRAAAELEW
                     SKDFAKEIMVKYGVSTAAYGTFSDFEEAKAYIEKHGAPIVVKADGLALGKGVVVAETV
                     EQAVEAAHEMLLDNKFGDSGARVVIEEFLEGEEFSLFAFVNGDKFYIMPTAQDHKRAY
                     DGDKGPNTGGMGAYAPVPHLPQSVVDTAVDTIVKPVLEGMIKEGRPYLGVLYAGLILT
                     ADGPKVIEFNARFGDPETQIILPRLTSDFAQNITDILDSKEPNITWTDKGVTLGVVVA
                     SKGYPLDYSKGVELPVKTDGDIITYYAGAKFAENSRALLSNGGRVYMLVTTADTVKEA
                     QASIYQELSQQKIEGLFYRTDIGSKAIK"
     gene            21270..21758
                     /gene="purE"
                     /locus_tag="VQ865_000900"
     CDS             21270..21758
                     /gene="purE"
                     /locus_tag="VQ865_000900"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009567721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HET3135258.1"
                     /translation="MKPVISIIMGSKSDWATMQKTAEVLDRFGVAYEKKVVSAHRTPD
                     LMFKHAEEARSRGIKIIIAGAGGAAHLPGMVAAKTILPVIGVPVNSRALSGVDSLYSI
                     VQMPGGVPVATMAIGEAGATNAALFALRLLSVEDQSIATALADFAEEQGKIAEESSNE
                     LI"
     gene            21745..22836
                     /gene="purK"
                     /locus_tag="VQ865_000901"
     CDS             21745..22836
                     /gene="purK"
                     /locus_tag="VQ865_000901"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HET3135259.1"
                     /translation="MSSSKTIGIIGGGQLGQMMAISAIYMGHKVIALDPAADCPASRV
                     AEIIVAPYNDVDALRQLADRCDVLTYEFENVDADGLDVVIKDGQLPQGTDLLRISQNR
                     IFEKDFLSNKAQVTVAPYKVVTSSLDLADIDLSKNYVLKIATGGYDGHGQNVIRSADD
                     LEEAYALADSAACVLEEFVNFDLEISVIVSGNGKEVTFFPVQENIHRNNILSKTIVPA
                     RISESLADKAKAMAVRIAEQLNLSGTLCVEMFATADDIIVNEIAPRPHNSGHYSIEAC
                     DFSQFDTHILGVLGAPLPAIKLHAPAVMLNVLGQHVEAAEKYVTENPSTHLHMYGKIE
                     AKHNRKMGHVTLFSDVPDSVEEFGEGIDF"
     gene            22846..23073
                     /locus_tag="VQ865_000902"
     CDS             22846..23073
                     /locus_tag="VQ865_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazole carboxylase"
                     /protein_id="HET3135260.1"
                     /translation="MIQIIVNAFIEKDKTGAVVEVLYASADQDKVQAKYEELAAQYPE
                     NYLAIYDVPLDTDLNTLDHYPSVFIGKEEFE"
     gene            23136..24434
                     /gene="purB"
                     /locus_tag="VQ865_000903"
     CDS             23136..24434
                     /gene="purB"
                     /locus_tag="VQ865_000903"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HET3135261.1"
                     /translation="MINRYSRPEMANIWSEENKYRAWLEVEILSDEAWAELGEIPKED
                     VALIRKKADFDIDRILEIEQETRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLYKQANDIIRRDLENFTNIIADKAKEHKFTIMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAAGVEAGKISGAVGNFANIPPFVEEYVCDKLGIRAQEISTQVLPRDL
                     HAEYFAVLASIATSIERMATEIRGLQKSEQREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MTGLARVIRGHMITAYENVALWHERDISHSSAERIITPDTTILIDYMLNRFGNIVKNL
                     TVFPENMIRNMNSTFGLIFSQRAMLTLIEKGMTREQAYDLVQPKTAYSWDNQVDFKPL
                     LEADSEVTSRLTQEEIDEIFNPVYYTKRVDDIFERLGLGD"
     gene            complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ865_000904"
     CDS             complement(24489..28424)
                     /gene="strH"
                     /locus_tag="VQ865_000904"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HET3135262.1"
                     /translation="MKHEKQQRFSIRKYAVGAASVLIGFAFQAQTVAADGVTTTTENQ
                     PTIHTVSDSPQSSENRTEETPKAELQPEAPKTVETETPATDKVASLPKTEEKPQEEVS
                     STPSDKAEVVTQTSAEKETANKKAEEASPKKEEAKEVDSKESNTDKTDKDKPAKKDEA
                     KAEADKPETEAGKERAATVNEKLAKKKIVSIDAGRKYFSPEQLKEIIDKAKHYGYTDL
                     HLLVGNDGLRFMLDDMSITANGKTYASDDVKRAIEKGTNDYYNDPNGNHLTESQMTDL
                     INYAKDKGIGLIPTVNSPGHMDAILNAMKELGIQNPNFSYFGKKSARTVDLDNEQAVA
                     FTKALIDKYAAYFAKKTEIFNIGLDEYANDATDAKGWSVLQADKYYPNEGYPVKGYEK
                     FIAYANDLARIVKSHGLKPMAFNDGIYYNSDTSFGSFDKDIIVSMWTGGWGGYDVASS
                     KLLAEKGHQILNTNDAWYYVLGRNADGQGWYNLDQGLNGIKNTPITSVPKTEGADIPI
                     IGGMVAAWADTPSARYSPSRLFKLMRHFANANAEYFAADYESAEQALNEVPKDLNRYT
                     AESVTAVKEAEKAIRSLDSNLSRAQQDTIDQAIAKLQETVNNLTLTPEALKEEEAKRE
                     VEKLAKNKVISIDAGRKYFTLNQLKRIVDKASELGYSDVHLLLGNDGLRFLLDDMTIT
                     ANGKTYASDDVKKAIIEGTKAYYDDPNGTALTQAEVTELIEYAKSKDIGLIPAINSPG
                     HMDAMLVAMEKLGIKNPQAHFDKVSKTTMDLKNEEAMNFVKALIGKYMDFFAGKTKIF
                     NFGTDEYANDATSAQGWYYLKWYQLYGKFAEYANTLAAMAKERGLQPMAFNDGFYYED
                     KDDVQFDKDVLISYWSKGWWGYNLASPQYLASKGYKFLNTNGDWYYILGQKPEDGGGF
                     LKKAIENTGKTPFNQLASTKYPEVDLPTVGSMLSIWADRPSAEYKEEEIFELMTAFAD
                     HNKDYFRANYNALREELAKIPTNLEGYSKESLEALDAAKTALNYNLNRNKQAELDTLV
                     ANLKAALQGLKPAATHSGSLDENEVAANVETRPELITRTEEIPFEVIKKENPNLPAGQ
                     ENIITAGVKGERTHYISVLTENGKTTETVLDSQVTKEVINQVVEVGAPVTHKGDESGL
                     APTTEVKPRLDIQKEEIPFTTVTRENPLLLKGKTQVITKGVNGHRSNFYSVSTSADGK
                     EVKTLVNSVVAQEAVTQIVEVGTMVTHVGDENGQAAIAEEKPKLEIPSQPAPSTAPAE
                     ESKALPQDPAPVVTEKKLPETGTHDSAGLVVAGLMSTLAAYGLTKRKED"
     gene            complement(28740..29456)
                     /locus_tag="VQ865_000905"
     CDS             complement(28740..29456)
                     /locus_tag="VQ865_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001007200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3135263.1"
                     /translation="MAIPKYQYIKDELKNKIISGQFSSGDKFYTEAELISMYDVSSIT
                     VVRALNDLAKDGYIVRQQGKGTFVSRARKHKLVEFSDIELFNAKDDKVTVLSIERGNK
                     LVYLEKLGLRGDQFYYKIERIRESNGVVYIYHTSYIPEQYINANYPNLEYYSSIYNRF
                     KLDYHIHMNDEHFEEINEIVFPTPEHAASVLGVDEQFPTVLQTKITKLESTGQVLEYS
                     ETYKRSDYYKIKFISCDRDH"
     gene            29804..31591
                     /locus_tag="VQ865_000906"
     CDS             29804..31591
                     /locus_tag="VQ865_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HET3135264.1"
                     /translation="MTRFEIRDDFYLDGKSFKILSGAIHYFRVPPEDWYHSLYNLKAL
                     GFNTVETYVAWNLHEPREGEFHFEGDLDLEKFLQIAQDLGLYAIVRPSPFICAEWEFG
                     GLPAWLLTKNMRIRSSDPAYIEAVGRYYDQLLPRLVPRLLDNGGNILMMQVENEYGSY
                     GEDKAYLRAIRQLMEECGVTCPLFTSDGPWRATLKAGTLIEEDLFVTGNFGSKAPYNF
                     SQMQEFFDEHGKKWPLMCMEFWDGWFNRWKEPIITRDPKELADAVREVLEQGSINLYM
                     FHGGTNFGFMNGCSARGTLDLPQVTSYDYDALLDEEGNPTAKYLAVKKMMATHFSEYP
                     QLEPLYKESMELDAIPLVEKVSLFETLDSLSSPVESLYPQKMEELGQSYGYLLYRTET
                     NWDAEEERLRIIDGRDRAQLYVDGQWVKTQYQTEIGEDIFYQGKKKGLSRLDILIENM
                     GRVNYGHKFLADTQRKGIRTGVCKDLHFLLNWKHYPLPLDNPEKIDFSKGWTQGQPAF
                     YAYDFTVEEPKDTYLDLSEFGKGVAFVNGQNLGRFWNVGPTLSLYIPHSYLKEGANRI
                     IIFETEGQYKEEIHLTRKPTLKHIKGENL"
     gene            31588..32064
                     /locus_tag="VQ865_000907"
     CDS             31588..32064
                     /locus_tag="VQ865_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3135265.1"
                     /translation="MTIVGCRIDGRLIHGQVANLWAGKLNVSRIMVVDDEVVNNDIEK
                     SGLKLATPPGVKLSILPVEKAAANILAGKYDSQRLFIVARKPDRFLGLVEAGVPLETL
                     NVGNMSQTPETRSITRSINVVDKDVEDFHKLAEKGVKLTAQMVPNDPISDFLSLLK"
     gene            32092..32997
                     /locus_tag="VQ865_000908"
     CDS             32092..32997
                     /locus_tag="VQ865_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3135266.1"
                     /translation="MIQWWQILLLTLYSAYQICDELTIVSSAGSPVFAGFITGLIMGD
                     VTTGLLIGGNLQLFVLGVGTFGGASRIDATSGAVLATAFSVSQGIDAPLAITTIAVPV
                     AALLTYFDVLGRMTTTFFAHRVDAAIERFDYKGIERNYLLGAIPWALSRALPVFFALA
                     FGGAFVQSVVDFVEAYKWVADGLTLAGRMLPGLGFAILLRYLPVKRNLHYLAMGFGLT
                     AMLTVLYSYVTGLGGAVAGIVGTLPAEVAEKIGFVNNFKGLSMIGISIVGIFLAVLHF
                     KNSQKVAVAAPSTPSESGEIEDDEF"
     gene            32984..33799
                     /locus_tag="VQ865_000909"
     CDS             32984..33799
                     /locus_tag="VQ865_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3135267.1"
                     /translation="MTNSNYKLTKEDFNQINKRSLFTFQLGWNYERMQASGYLYMILP
                     QLRKMYGDGTPELKEMMKVHTQFFNTSPFFHTIIAGFDLAMEEKDGVGSKDAVNGIKT
                     GLMGPFAPLGDTIFGSLVPAIMGSVAATMAIAGQPWGIFLWIAVAVAYDIFRWKQLEF
                     AYKEGVNLINNMQSTLTALIDAASVLGVFMMGALVATVINFEISYKLPIGEKMIDFQD
                     ILNQIFPRLLPAIFTAFIFWLLGKKGMNSTKAIGIIIVLALALSALGHFALGM"
     gene            33806..34210
                     /locus_tag="VQ865_000910"
     CDS             33806..34210
                     /locus_tag="VQ865_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007284837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3135268.1"
                     /translation="MTKSLILVSHGRFCEELRGSTEMIMGPQDNIYTVALLPEDGPEE
                     FTAKFEAVIEGLDDFLVFADLLGGTPCNVVSRLIMEGRDIDLYAGMNLPMVIEFINAS
                     LTGADADYKSRAAESIVKVNDLLAGFDDDEDE"
     gene            34509..35675
                     /locus_tag="VQ865_000911"
     CDS             34509..35675
                     /locus_tag="VQ865_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004257942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HET3135269.1"
                     /translation="MLHYTKEDLLELGAEITTREIYQQPDVWREAFEFYQAKREEIAA
                     FLQEIADKHDYIKVILTGAGTSAYVGDTLLPYFKEVYDERKWNFNAIATTDIVANPAT
                     YLKKDVATVLVSFARSGNSPESVATVDLAKSLVDELYQVTITCAADGKLALQAHGDDR
                     NLLLLQPAVSNDAGFAMTSSFTSMMLTALLVFDPTEFAVKSERFEVVSSLARKVLDKA
                     EDVKELVDLDFNRVIYLGAGPFFGLAHEAQLKILELTAGQVATMYESPVGFRHGPKSL
                     INDNTVVLVFGTTTDYTRKYDLDLVREVAGDQIARRVVLLSDQAFGLENVKEVALGCG
                     GVLNDIYRVFPYIVYAQLFALLTSLKVENKPDTPSPTGTVNRVVQGVIIHEYQK"
     gene            35791..36828
                     /locus_tag="VQ865_000912"
     CDS             35791..36828
                     /locus_tag="VQ865_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HET3135270.1"
                     /translation="MKAYTERVFGNVEGEDVLAYRFETDGGYQLEVMTYGATILRYVA
                     PDKAGNFANVILGFDDFDSYVGNSPKHGASVGPVAGRIAGATFELNGKTYDLEVNNAS
                     NCNHSGSTGWDSSLFEVEEVSDHGLTLYTERTDGTGGFPGNLKIWISYHLEETGAYEI
                     SYKVTTDQDTLVNPTNHSYFNLSGDFTQTIDRHVFQLNTEGIYSIAPDGVPAKTPEAN
                     RDVVKHVYNGTLLKDIFAEEDEQIQLASGLDHPFALPAGHDNAGFLYDQNSGRFLLFK
                     TEAPCFVVYTANFVDESVIIGGQPMLQHNGIALEAQALPDAIHSDLKGQVILKAGQTF
                     TSKTRYELVVK"
     gene            37035..37889
                     /locus_tag="VQ865_000913"
     CDS             37035..37889
                     /locus_tag="VQ865_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000220702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3135271.1"
                     /translation="MTYEYKSHIYLAETVLNVKDLASQTAFYQQVIGLEILSQTETES
                     ILGLGGKVLVQLIQAQESGEVREHYGLYHLAILLPTRKALADVLKHLTDLQIPLVGGA
                     DHGYSEAIYLEDLEGNGIELYRDKPVSTWDIREDGRIIGVTEALAAQDIYELGERVEP
                     FILAEGTRMGHIHLSVKDSRKSSQFYQKVLGLEDKFSVPSASWIAAGDYHHHLAVNEW
                     GGKGLASRKQGLPGLAYYVIEVAHKKELLTIAQRAQEVDAPIKWMTSSQLEITDSDGI
                     VTCIRLAR"
     gene            38039..38279
                     /locus_tag="VQ865_000914"
                     /pseudo
     CDS             38039..38279
                     /locus_tag="VQ865_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845567.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensing transcriptional repressor"
BASE COUNT        10751 a         7406 c         9115 g        11139 t
ORIGIN      
        1 aacatatata cggcaaggcg acgttgacgt ggtttgaaga gattttcgaa gagtattaga
       61 aaatgccgat aagggtctgc ataccaaggc tggtgaggat gatggcaatc cagcagacgg
      121 ctccgagaac aatggatttt ccactggatt tgaccatagc gaccagatta gttttgagac
      181 cgatggcact catggccatg ataatgagga atttagagag ttgtttgaga ggggtaaaga
      241 aactactaga cacaccgaga gaggtcagaa gggtggttag gagcgatgca aggatgaagt
      301 aaaggataaa aagtgggaag acttttttca gttgtaagcc ttgcttattt ttttgctcgc
      361 gactttgcca gtaggagaga aagatagtga tggggatgat agctagggtg cgcgtgagtt
      421 tgacaatggt tgcggattcg agggcattgg tctggtagag actgtcccaa gcgctagctg
      481 tggcggttac agaggaagta tcattgaccg cagttcctgc aaagagggcg aagccgtcat
      541 tggatagatg aagccaggtg ccgagggttg gaaagatgag cgcagccaag acattgaaga
      601 aaaagataac ggagatggct tgggctactt ccttttcctt agcatggata acaggcgctg
      661 tcgctgcaat ggcagaaccc ccacagatag aagaacctac tccaatcaag gtagccagtt
      721 ttgtatccag ggcaaagaag cgctggaaga ggtaggcaac aatcaaggct attgaaatgg
      781 tggaaaggat gacagggagt gaagattgcc caactgcgaa gacttgagag atattgagac
      841 caaaaccaag caagataacg gcatactgga gcaatttctt ggaactaaag gtcaatccag
      901 catccagttg tttataagac gagagaaagg gatgtaggag catgcccata aaaatcgcaa
      961 aaacgggtgc gccaatcaca gggaagaatc ctcctaagta ccaagatacg atagaaatga
     1021 gaaggcagac caagatgcct gctccatttt ttgatagaaa tgacataaaa acctccaaat
     1081 agaatctgtt accattatag acctgtaaag aggaaaagta aaatagaaag tggaaagcta
     1141 ttctctaatg tatttttgcg gtcgggaggc ttttgtagta taatagagat acgttttgaa
     1201 agtaggaggt atctatggac ttaactaagc gctttaataa acagttagat aaaattcaag
     1261 tttcgttgat tcgtcagttt gaccaggcta tttcggagat tcctggggtc ttgcgtttga
     1321 ccttggggga acctgatttt acaacgccag accatgtcaa ggaggcggcc aagcgagcga
     1381 ttgatcagaa ccaatcctac tatacaggga tgagtggtct gctgactcta cgtcaggcag
     1441 ctagtgactt tgttaaggaa aagtaccaac tggactatgc tcctgaaaat gaaatcttgg
     1501 ttacaattgg ggcgacagag gctttatctg cgactttgac ggctattttg gaagagggag
     1561 acaaggtact tttgccagct cctgcttatc caggctatga accgattgtt aacttagttg
     1621 gggcagaaat tgttgagatt gatacgactg aaaatggttt tgtcttgact cctgagatgt
     1681 tggagaaggc cattttggag cagggtgata agctcaaggt ggttattctc aactatccag
     1741 ccaatccgac aggaattacc tacagtcgag agcagttaga gaccttggca gctgttttac
     1801 gcaagtatga aatttttgtt gtctgtgatg aggtttactc agaattgacc tacacaggcg
     1861 aagcccatgt gtctctagga acgatgttga gagaccagac tattattatc aatggtttgt
     1921 ctaaatcgca tgccatgaca ggttggcgtt tggggctgat tttcgctcct gcgaccttca
     1981 cagcccagtt aatcaagagt caccagtact tggtcactgc cgcaaatacc atggcgcaac
     2041 atgctgcggt agaagccttg acggctggta aaaacgatgc ggagcccatg aagaaggaat
     2101 atatccaacg tcgggactat atcatcgaaa aaatgactgc tcttggtttt gagattatca
     2161 aaccagacgg tgccttctat atttttgcta aaattccagc gggctacaat caagactcct
     2221 ttgcttttct gaaggatttt gctcagaaga aggccgttgc ctttatccct ggtgcagcct
     2281 ttggacgtta cggggaaggc tacgtccgcc tatcttatgc agccagcatg gagactatca
     2341 aagaagccat gaaacgactt gaggagtaca tgagagaagc atgattcagt ctatcacgag
     2401 tcaaggcttg gtgctttaca atcgcaattt tcgtgaggat gacaagctcg tcaaaatttt
     2461 tacagagcag gttggcaaac gcatgttttt tgtcaaacac gctggtcagt ctaagctggc
     2521 gcctgttatt cagcccttgg tgctggcacg atttctcttg cgaatcaatg atgacggact
     2581 cagttacatc gaagactatc atgaggtcat gacttttccc aagattaata gtgacctctt
     2641 tgtcatggcc tatgcgacct atgtggcagc tcttgcagat gctagtttgc aggacaatca
     2701 gcaggatgct cccttgtttg cttttttgca aaagactttg gagttgatgg aagcaggctt
     2761 ggattatcag gttttgacca atatttttga aattcaaatt ttgactcgat ttggaatcag
     2821 cctcaatttt aatgagtgtg tcttctgcca tcgggttggt caggcttttg acttttcttt
     2881 caaatatgga gcctgcctct gtccagagca ttatcatgag gataagagac gttgtcatct
     2941 caatcccaat atcccctatc tgctcaatca atttcaagct attgattttg agactttgga
     3001 gaccatttcg ctcaagcctg gaatcaagca agagctacgc caatttatgg atcaattata
     3061 tgaagagtac gttgggattc acctaaaatc aaagaaattt attgattccc tagcagactg
     3121 gggacaatta ctaaaagagg aaaagaaatg aaaaaaatcg cagtagatgc catggggggc
     3181 gattacgcac ctcaggccat tgttgagggt gtcaatcaag ccctatctga cttttcagat
     3241 atcgaggttc aactttacgg agatgaagct aaaatcaagc aatatctgac agcgacagag
     3301 cgcgtcagca ttatccatac ggatgagaag attgattcgg atgatgaacc tacgagagct
     3361 attaggaata agaaaaatgc cagtatggta ttggcagcca aggctgtcaa agatggtgaa
     3421 gcagacgctg tcctttcggc tgggaataca ggtgccttgt tggctgctgg attcttcatc
     3481 gtgggtcgta tcaagaatat cgaccgtcct gggcttatgt cgactttgcc gactgtagat
     3541 gggaagggat ttgacatgct agacctcggt gccaatgcgg aaaatacagc ccagcacctc
     3601 catcaatacg cggttctagg atccttctat gctaaaaatg ttcgtggcat tgcgcaacca
     3661 cgtgttggct tgctcaataa cggaacagag agtagcaagg gcgatccgct tcgtaaggaa
     3721 acttatgaat tactagtggc tgatgaaagt ttgaacttta tcggaaatgt ggaagcgcgt
     3781 gatttgatga atggcgttgc agatgttgtt gtggcagatg gtttcacggg aaacgctgtg
     3841 ctcaaatcca tcgaagggac agctatggga atcatgggct tgctcaagac agctattaca
     3901 ggtggtggtc ttcgagcgaa actaggtgcc ctccttctca aggacagcct cagaggtttg
     3961 aaaaaacaac tcaattattc agatattggt ggagcggtct tgtttggtgt taaggcacct
     4021 gttgtcaaga ctcatggctc aagcgatgcc aaggctgttt atagtacgat tcgtcagatc
     4081 cgtaccatgc tagaaacaga cgtggttgcc cagactgcgc gtgaattttc aggagaataa
     4141 aagagatgac agaaaaagaa atttttgacc gtattgtgac cattatccaa gagcgacagg
     4201 gagaggactt tgtcgtgaca gaatccttga gtctgaaaga cgatttggat gcggattctg
     4261 ttgacttgat ggagtttatc ttgactctgg aagatgaatt tagtatcgaa atcagcgatg
     4321 aagaaattga ccaactccaa aacgtaggag atgtggttaa aatcattcaa ggaaaatagc
     4381 aatcggagtt ccaagtcaac ggaagtagat ggtttttaga aatgagaaat atcggacaag
     4441 ctggtaaaat cttggctgac agtggttatc aagggctcat gaagatatat cctcaagcac
     4501 aaactccacg taaatccagc aaactcaagc cgctaacagt tgaagataaa gcctgtaatc
     4561 atgcgctatc taaggagaga agcaaggttg agaatatctt tgccaaagta aaaacgttta
     4621 aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga atgaatttga
     4681 ttgctggtat tatcaatcat gaactaggat tctagttttg caggaagtct aatagtaaaa
     4741 aagtgattag aaaacatctt ttttaaaaat agagatgatt ttgaaacaaa aaagctaatt
     4801 caagacgttt ctatgccaat tcaagatttg gatgaaaaaa attaatagat actgttatac
     4861 taaacttgtc aagtttgtaa caagacaaat attaaaaata aaaaagaggt attcgttatg
     4921 aatacaaaaa agatgtcaca atttgaaatt atggatactg agatgcttgc ttgcgttgaa
     4981 ggtggcggat gcaattgggg agattttgcc aaagcaggtg ttggaggagg agcagtacga
     5041 ggtcttcagc taggaattaa aacaagaaca tggcaaggtg cagcaactgg tgctgcggga
     5101 ggagctatac ttggaggtgt ggcctatgca gcgacatgtt ggtggtaatt atggatttta
     5161 aaagttttat tattggttta gtagttggta tatttggtcc ttatatggat gatttaatta
     5221 gaaaaaaatt tttaaagtct tcggagaaga aaacagaaaa atctgttaaa aaataatcaa
     5281 aactataaat gatgaatctg aatcaaaatt attttgcgca tgtaaatagg agtcttatag
     5341 taacgagtca aaaaaggagt aactatgaat cgtaatttag aacggtgtta tctattctga
     5401 ctaggaatag atcataccag aggtagctta gaaatagcag agacattaga aattgaagta
     5461 ataaatagga tgtcgtaagt gttactatca atgatttatt tgtttcaagc ttgtctaggg
     5521 tgacagtaaa aaatcaattt cctttcaata gcatattttt agtgggcagt actcttgttc
     5581 tgcctatttt tttatccaaa aagtgcagtt gggagggaga taggctcatt tgggaaggaa
     5641 gtccagtttt tgtttagtga ttggggtaag atagttgtta tcagatgagt ttatactctt
     5701 cgaaaatcaa attcaaacca cgtcaacgtc gccttgccgt atatatgtga ctgacttcgt
     5761 cagtcctatc tacaacctca aaacagtgtt ttgagcagcc tgcggctagt ttcctagttt
     5821 gctctttgat tttcattgag tattagggaa aaggagatga atatgaaatt tgggaaacgt
     5881 cactatcgtc cgcaagtgga tcagatggac tgcggtgtag cttcattagc catggttttt
     5941 ggctactatg gtagttatta ttttttggct cacttgcgag aattggctaa gacgaccatg
     6001 gatgggacga cggctttggg cttggtcaag gtggcagagg agattggttt tgagacgcga
     6061 gccattaagg cggatatgac gctttttgac ttgccggatt tgacttttcc ttttgttgcc
     6121 catgtgctta aggaagggaa attgctccac tactatgtgg tgactgggca ggataaggat
     6181 agcattcata ttgccgatcc agatcccggg gtgaagttga ctaaactgcc acgtgagcgt
     6241 tttgaggaag aatggacagg agtgactctt tttatggcac ctagtccaga ctataagcct
     6301 tataaggaac aaaaaaatgg tctgctctct tttatcccta tattagtgaa gcagcgtggc
     6361 ttgattgcca atatcgtttt ggcaacactc ttggtaaccg ggattaacat tgtgggttct
     6421 tattatctgc agtctatcat tgatacctat gtgccagatc agatgcgttc gacactaggg
     6481 attatttcta ttgggctagt catcgtctac atcctccagc aaatcttgtc ttacgctcag
     6541 gagtatctct tgcttgtttt ggggcaacgc ttgtcgattg acgtgatttt gtcctatatc
     6601 aagcatgttt ttcacctccc tatgtccttc tttgcgacac gcaggacagg ggagatcgtg
     6661 tctcgtttta cagatgctaa cagtatcatc gatgcgctgg cttcgaccat cctttcgatt
     6721 ttcctagatg tgtcaacggt tgtcattatt tcccttgttc tattttcaca aaataccaat
     6781 ctctttttca tgactttatt ggcgcttcct atctacacag tgattatctt tgcctttatg
     6841 aagccgtttg aaaagatgaa tcgggatacc atggaagcca atgcggttct gtcttcttct
     6901 atcattgagg acatcaacgg tattgagact atcaagtcct tgaccagtga aagtcagcgt
     6961 taccaaaaaa ttgacaagga atttgtggat tatctgaaga aatcctttac ctatagtcga
     7021 gcagagagtc agcaaaaggc tctgaaaaag gttgcccatc tcttgcttaa tgtcggcatt
     7081 ctctggatgg gggctgttct ggtcatggat ggcaagatga gtttggggca gttgattacc
     7141 tataatacct tgctggttta ctttaccaat cctttggaaa atatcatcaa tctgcaaacc
     7201 aagcttcaga cagcgcaggt tgccaataac cgtctaaatg aagtgtatct agtagcttct
     7261 gagtttgagg agaagaaaac agttgaggat ttgagcttga tgaagggaga gatgaccttc
     7321 aagcaggttc attacaagta tggctatggt cgagacgtct tgtcggatat caatttaacc
     7381 gttccccaag ggtctaaggt ggcttttgtg gggatttcag ggtcaggtaa gacgactttg
     7441 gccaagatga tggttaattt ttacgaccca agtcaagggg agattagtct gggtggtgtc
     7501 aatctcaatc agattgataa aaaagccctg cgccagtaca tcaactatct gcctcaacag
     7561 ccctatgtct ttaacggaac gattttggag aatcttcttt tgggagccaa ggaggggacg
     7621 acacaggaag atatcttacg ggcggtcgaa ttggcagaga ttcgagagga tatcgagcgc
     7681 atgccactga attaccagac agaattgact tcggatgggg cagggatttc aggtggtcaa
     7741 cgtcagagaa tcgctttggc gcgtgctctc ttgacagatg cgccggtctt gattttggat
     7801 gaggcgacta gcagtttgga tattttgaca gagaagcgga ttgtcgataa tctcatggct
     7861 ttggacaaga ccttgatttt cattgctcac cgcttgacta ttgctgagcg gacagagaag
     7921 gtagttgtct tggatcaggg caagattgtc gaagaaggaa agcatgctga tttgcttgca
     7981 cagggtggct tttacgccca tttggtcaat agctagaaag aggagaggat gaaaccagaa
     8041 tttttagaaa gtgcggagtt ttataatcgt cgttaccata atttttccag tagtgtgatt
     8101 gtacccatgg cccttctgct cgtgttttta cttggctttg caactgttgc agagaaggag
     8161 atgagtttgt ccactagagc tactgtcgaa cctagtcgta ttcttgcaaa tatccagtca
     8221 actagcaaca atcgtattct tgtcaatcat ttggaagaaa ataagctggt taagaagggg
     8281 gatcttttgg ttcaatacca agaaggggca gagggtgtcc aagcggagtc ctatgccagt
     8341 cagttggaca tgctaaagga tcaaaaaaag caattggagt atctgcaaaa gagcctgcaa
     8401 gaaggggaga accactttcc agaggaggat aagtttggct accaagccac ctttcgcgac
     8461 tacatcagtc aagcaggcag tcttagggct agtacatcgc aacaaaatga gaccatcgcg
     8521 tcccagaatg cagcagctag ccaaacccaa gccgaaatcg gcaacctcat cagtcaaaca
     8581 gaggctaaaa ttcgcgatta ccagacagct aagtcagcta ttgaaacagg tgcttccttg
     8641 gccggtcaga atctagccta ctctttttac cagtcctaca agtctcaggg cgaggaaaat
     8701 ccccaaacta aggttcaggc agttgcacag gttgaagcac agatttctca gttagaatct
     8761 agtcttgcta cttaccgtgt ccagtatgca ggttcaggta cccagcaagc ctatgcgtca
     8821 gggttaagca gtcaattgga atcccttaaa tcccaacact tggcaaaggt tggtcaggaa
     8881 ttgacccttc tagcccagaa aatcttggag gcagagtcag gtaagaaggt acagggaaat
     8941 cttttagaca aggggaaaat tacggcgagt gaggatgggg tgcttcatct taatcctgag
     9001 accagtgatt ctagcatggt tgcagaaggt gccctactag cccaacttta tccatctttg
     9061 gaaagagaag ggaaagccaa actcacagcc tatctaagtt caaaagatgt agcaagaatc
     9121 aaggtcggtg attctgttcg ctatactacg actcatgatg ccgggaatca acttttccta
     9181 gattctacta ttacaagtat tgatgcgaca gctactaaga ctgagaaagg gaatttcttt
     9241 aaaatcgagg cggagactaa tctaacttcg gagcaggctg aaaaacttag gtacggggtg
     9301 gaaggccgct tgcagatgat tacgggcaag aaaagttatc tacgttatta tttggatcaa
     9361 tttttgaaca aagagtaatg ttcgtgtttt tagagttaaa taatttttaa actgtgagaa
     9421 agattcttct tgcagttttt tctttacaat ttttgaaaaa tatctactat ttattcggtt
     9481 aaattcttgt gttttttggt tttttgtggt aaaatgtgct caagtaatac gaaaggcgaa
     9541 ctttaaaatg tcaaaacaat tgatctattc gggaaaagct aaagatatct atacaactga
     9601 ggatgaaaat cttattattt caacttacaa ggaccaggcg actgctttca atggtgtcaa
     9661 gaaggagcag attgcaggta agggagtctt gaataatcag atctcatctt ttatttttga
     9721 gaaattaaat gcggctggtg tggcgactca ctttgtggag aaactttcag acacggaaca
     9781 actcaataaa aaggttaaga ttattccttt ggaagtcgtg ctccgcaact atactgctgg
     9841 ttccttttca aaacgttttg gtgtggatga aggaatcgcc ttggagactc cgattgtcga
     9901 attttactac aaaaatgatg atttggatga tccatttatc aatgatgagc atgtgaaatt
     9961 cctacagatt gcggatgacc agcagattgc ctacttgaag gaagaaacgc gtcgtatcaa
    10021 tgaactattg aaagtctggt ttgctgagat tgggcttaaa ttgattgact ttaagctaga
    10081 gttcggtttt gacaaggatg gcaagattat cttggcagac gaattttcac cagataactg
    10141 ccgcttgtgg gatgctgatg gcaaccacat ggataaggat gttttccgta gaggattggg
    10201 agaactaacc gacgtttatg agattgtttg ggaaaagttg caggaattga aataatctgt
    10261 ttgcaatgga aaaccttcgt ctctcaacta aaaggactca ggctgaaaag gtcccccaga
    10321 ccttttcact ctgtagagaa ctaggtgaac taaccgatgt ttacgaaatt gtctaggaaa
    10381 agttgcaggg tttaaaataa caacctcaag gctgtttggg aatattgcaa gagctgaaat
    10441 aaaggaataa gaattgatgg ataaacgtat ttttgttgaa aaaaaggctg attttcaggt
    10501 caagtcagag agtttggtta gagagctcca gcacaacttg ggactgtcaa gcttgaaaag
    10561 tattcgtatt gtgcaagtat atgatgtatt tgacttggct gaggacttgt ttgcacctgc
    10621 agagaagcac attttctctg agcaggtaac cgaccatgtt ttagatgaag tatctgtgca
    10681 ggcggatctt gctaactatg ctttctttgc cattgaaagt ctaccagggc agtttgacca
    10741 gcgtgcagct tcgtcacagg aagccttgct tttgttggga agttcgagtg acgtgacagt
    10801 caacacagcc caactttact tggtgaataa agatattgat gtgactgagt tggaagctgt
    10861 caaaaactac ctgctcaatc cagttgattc tcgtttcaag gatatcacga cagggattgc
    10921 caagcaggag ttttcagagt cagacaagac cattccaaaa ttgactttct ttgaaagcta
    10981 tacagcagaa gactttgctc gctacaaggc cgaacaaggg atggccatgg aagtggatga
    11041 tttgctcttt atccaagact actttaagtc aatcgggcgc gtgccaactg agactgaact
    11101 caaggttttg gacacttact ggtctgacca ctgccgtcat acgacttttg agacagagtt
    11161 gaaacacatc gacttttcag cttctaaatt tcaaaagcaa ttgcagtcaa cctatgacaa
    11221 gtatattgcc atgcgcgagg aattaggtcg gtctgaaaaa ccacaaacct tgatggatat
    11281 ggcgactatt ttcggtcgtt atgagcgtgc taatggacga ttggatgata tggaagtctc
    11341 tgacgaaatc aatgcctgct cagttgaaat tgaagtggac gttgatggtg tcaaggaacc
    11401 ttggctcctc atgtttaaaa atgaaaccca caaccatcca acagaaattg agccatttgg
    11461 tggagcggct acctgtatcg gtggagctat tcgtgatccg ttgtcaggcc gttcctatgt
    11521 ttaccaagcc atgcgtattt caggtgctgg tgatattaca gcaccgattt cggaaactcg
    11581 tgctgggaaa ttgccacaac aagtcatttc taaaacagca gctcatggtt attcttcata
    11641 tggtaaccag attgggcttg ccacaaccta cgttcgtgaa tacttccacc caggctttgt
    11701 agctaaacgt atggaacttg gtgccgttgt tggtgcggct cccaagggca atgttgtccg
    11761 tgaaaaacct gaagcaggtg atgtgatcat ccttctcgga ggcaaaacag gtcgtgatgg
    11821 tgtcggtggt gcgacgggct cttctaaggt tcaaacagtt gagtctgtag agactgctgg
    11881 tgctgaggtt caaaaaggaa atgccatcga agaacgcaag attcagcgcc tcttccgtaa
    11941 tggcaatgtc actcgtctga tcaagaagtc caatgacttt ggggcaggcg gcgtctgtgt
    12001 ggctatcggt gaattggcag acggtcttga aatcgacctc aacaaggtgc ctcttaaata
    12061 ccagggcttg aatggtacag aaattgccat ctctgaatca caagaacgga tggcggtcgt
    12121 ggttcgtcct gaagatgtgg atgccttcgt tgccgaatgt aacaaagaaa atattgatgc
    12181 tgttgtggtg gcgacagtaa ctgaaaaacc aaatcttgtc atgaactgga atggtgagac
    12241 aatcgttgac ttggagcgtc gtttccttga caccaatggt gtgcgcgtgg ttgtcgatgc
    12301 caaagttgtg gacaaggatg tcaaactccc agaagagcgt caaacatctg ctgaaacact
    12361 ggaatcagat acccttacgg ttctatctga cctcaaccat gcaagtcaaa aaggattaca
    12421 gactgtcttt gactgctctg ttggacgctc aacggttaat cacccacttg gtggtcgtta
    12481 ccaactcaca ccaactgagg catctgtgca gaaattgcca gttcaacacg gtgtgactca
    12541 tactgcgtcg gtcattgctc aaggtttcaa ctcatatgta gctgaatggt ctccatacca
    12601 cggtgctgct tatgcggtta tcgaagcaac tgctcgtttg gtggctgctg gtgccaactg
    12661 gtctaaggct cgtttctctt accaagaata tttcgagcgg atggacaagc aagcagagcg
    12721 ttttggtcag ccagtagccg cccttctagg ctctattgaa gctcagattc aacttggctt
    12781 gccatctatc ggtggtaagg actccatgtc tggtaccttt gaagaattga ccgttccgcc
    12841 aaccttggtt gcctttgggg tgacgacggc agatagccgt aaggtgctct ctccagaatt
    12901 taaagctgtt ggggaaaata tctactacat cccaggtcaa gccctctctg cagagattga
    12961 ttttgacttg attaagaaaa attttgctca gtttgaagca agccaagctg accataaagt
    13021 gacatctgca tcagctgtca aatacggtgg tgtagttgaa agtttggctc ttgctacctt
    13081 tggaaactat attggtgcag aggtgacctt gcctgaactt aaaacagctt tgacagctca
    13141 attaggcggc tttgtcttca catctcctga agaaattgct ggagtagaga agattggaca
    13201 aacgaaagca gactttacac tgactgtcaa cggtgtgaag ctagatggac acaagcttga
    13261 cagtgcattt caagggacat tggaagaagt ttacccaaca gaatttaccc aagcgaaaga
    13321 actagaagaa gtaccagctg tggcatcaga tgttgtgatt aaagccaaag aaaaggttga
    13381 aaaacctgtg gtttacatcc cagtctttcc aggaaccaac tcagaatatg attcagctaa
    13441 ggccttcgaa aaagaaggtg cagaggtcaa tttggtgcca ttcgtgacct tgaatgaaga
    13501 agctattgtc aagtcagttg aaactatggt tgacaatatc gacaagacta atattctctt
    13561 ctttgccggt ggattctcgg ctgcggatga accagatggt tcagctaagt ttatcgtcaa
    13621 tatcctgctt aatgaaaaag tgcgtgtggc tattgatagc tttatcgccc gtggtggctt
    13681 gattatcggt atttgtaatg gattccaagc cttagtcaaa tcgggtctcc taccatacgg
    13741 aaactttgaa gatgctaaca gtactagtcc aaccctcttc tacaatgatg ccaaccaaca
    13801 cgtggccaag atggtggaaa ctcgcattgc caataccaac tcaccatggt tggctggtgt
    13861 gcaagtgggc gatatccacg ctattcctgt ttcgcacggt gaagggaagt ttgtcgtgac
    13921 ggctgaggaa tttgcagagc tccgtgacaa tggacaaatt ttcagccaat acgttgactt
    13981 taacggtaaa ccaagtatgg attctaagta caatccgaat ggttctgtcc atgccatcga
    14041 aggaattacc agcaagaatg gtcaaatcat cggtaagatg ggccactcag aacgttatga
    14101 ggatggtctt ttccaaaata tcccaggcaa taaagaccaa cacctgttcg catcagcggt
    14161 taaacatttc actggaaaat aagacttaca gattttctaa tagatagtat cagtaatgta
    14221 aaagtcatgt aaatctagct cttgatgatt acaaatgaaa attaggtata aaaaatgaca
    14281 tacgaagtaa aatctcttaa tgaagaatgt ggtgttttcg gtatttgggg acatccagat
    14341 gctgctaagt tgacctactt tggactccac agtcttcaac accgtggtca ggagggggca
    14401 ggaatcctct ccaacgatca aggacaactg aagcgccatc gtgacatggg gcttttatca
    14461 gaagttttca gaaatccatc taatttggat aaattgacag gagctggtgc gattgggcat
    14521 gtgcgttatg cgactgctgg cgaagcttct gttgataaca tccaaccctt cctcttccgt
    14581 tttcacgata tgcagtttgg tttggctcat aatggaaatc tgaccaatgc agcctctctc
    14641 aagaaagaac tggaacaaag aggagcaatt ttcagcgcga cttcggactc tgaaatcttg
    14701 gctcacctca ttcgtcgcag tcataatcct agcctgatgg gcaaaatcaa ggaagcgctc
    14761 agccttgtca aaggtggttt tgcctatatc ttgctgtttg aggacaagtt gattgcggct
    14821 cttgacccta atggctttcg tccgctttct atcgggaaaa tggccaacgg agcggtggtt
    14881 gtttcctctg aaacctgtgc ttttgaggtc attggtgccg agtggatttg tgatttgaag
    14941 ccaggtgaga ttgtgatcat tgatgacgag ggcattcagt atgacagcta tacagatgat
    15001 acccagttgg cgatttgttc tatggagtat atctactttg cccgccctga ttctaatatc
    15061 cacggtgtca atgtccatac ggcacgtaag agaatgggag cgcaattggc gcgagaattt
    15121 aagcatgagg cagatattgt agttggtgtg cccaattctt ccctaagcgc ggctatggga
    15181 tttgcggaag aatcaggctt accaaatgaa atgggtctga tcaaaaacca atacacccag
    15241 cgaactttta tccaaccgac tcaagaattg cgggagcaag gagtgcggat gaaactgtct
    15301 gctgtttcgg gtgttgtcaa aggcaaacgt gtggtcatgg tggatgattc cattgtacgt
    15361 ggaacaacct ctcgtcgtat cgttcagctc ttgaaagaag cgggtgcgac tgaggttcac
    15421 gttgccattg gaagtcctgc actagcgtat ccatgtttct acgggattga tatccagacc
    15481 cgtcaggagc tgattgcagc caatcatacg gtcgaagaaa ctcgccaaat cattggtgcg
    15541 gacagtctga cttatctttc aattgatggc ttgattgagt cgattggtat cgaaacagat
    15601 gcgccgaacg gtggtctctg tgtcgcttac tttgacggtg actacccaac gcctctctat
    15661 gactacgaag aagactatcg tagaagtttg gaagaaaaga ccagttttta caagtaggcg
    15721 acagattctc cattaaagaa aaggaaaaaa taaatgacaa ataaaaatgc atatgcccag
    15781 tcgggtgtgg atgttgaagc gggttatgaa gttgttgaac ggattaaaaa gcacgtggcc
    15841 cgtacggaga gtgcaggtgt catgggagct cttggtggct ttggtggtat gtttgatctt
    15901 tccaagactg gggttaaaga acccgtcttg atttcaggga ctgacggtgt cggaaccaag
    15961 ctcatgttgg ctatcaagta cgacaagcac gataccatcg ggcaggactg tgtggccatg
    16021 tgtgtcaacg acatcattgc tgcaggtgcg gaacccctct attttctcga ctacgtagcg
    16081 acagggaaga atgaaccagc taagctagaa caagtggttg ctggtgtggc agaaggttgt
    16141 gtgcaggctg gtgctgccct catcggtggg gaaacggctg aaatgccggg catgtacggc
    16201 gaagacgact atgacttggc tggttttgcg gtcggtgtgg ctgaaaaatc tcaaatcatt
    16261 gacggttcaa aggtggtaga gggagatgtt cttctcggac ttgcttcaag tgggattcac
    16321 tcaaatggtt actctttggt tcgtcgtgtc tttgcggatt acacaggtga ggaagtccta
    16381 ccagaattgg aaggcaagaa acttaaggaa gttctacttg agccgactcg tatctatgtc
    16441 aaggctgtct tgccgctcat caaagaagag ttggtcaacg gcattgccca catcacaggt
    16501 ggtggcttta tcgaaaatgt ccctcgtatg tttgcagatg acctagctgc tgaaattgat
    16561 gaaagcaaag ttccagtgct tccaattttc aaagcccttg aaaaatatgg tcagattaaa
    16621 cacgaagaaa tgtttgaaat cttcaatatg ggtgtgggac ttatgttggc ggtcagccct
    16681 gaaaatgtag agcgtgtaaa agaattgttg gatgaagcag tctatgaaat tggtcgcatc
    16741 gtcaagaaag aaaacgaaag tgtcattatc aaatgaaaaa aatagcggtt tttgcctctg
    16801 gtaatggctc aaattttcag gtgattgccg aagaatttcc agtggagttt gtcttttcag
    16861 accatcgtga tgcctatgtg cttgagcgtg caaagcagct cggcgttctg tcctatgctt
    16921 ttgaactcaa ggagtttgag agcaaggcag actacgaagc agcccttgtc gaactcttgg
    16981 aagaacacca gattgacttg gtttgcctag caggctacat aaaaatcgtt ggaccaacct
    17041 tattgtcggc ttatgaaggt cggattgtca atattcatcc agcctacttg ccagaatttc
    17101 caggagctca tgggattgag gatgcttgga atgctggcgt gggtcagtct ggtgtgacca
    17161 ttcactgggt ggattcgggt gtggatacag gccaggtcat caaacaggtt cgtgtgccac
    17221 gactagctga tgataccatt gacagatttg aagctcgcat ccatgaagca gagtacaggt
    17281 tgtatctgga agtagtgaag gctctattta cagattgact ttttgatgat tcatatgata
    17341 tctttgattt taaattggag tcagtgtttg ttgaagacgg cttcaaacgg aggtatttgt
    17401 aatgttagaa tctaaaaaaa caactcgata tgtattttat gtctatctga tgttattaac
    17461 ttggggaatc ttatttaagt ttgaaacaaa tcctgaattt atagcatttt tcttagctcc
    17521 aaggtatatc aattggattc cattttcaga accactaata gtcgatggaa aaattgtttt
    17581 tgctgaaatg ttatttaatc tgatttcctt tattccatta ggtgtttgtt tccctttgat
    17641 aaaaactaat ttatctagtt taagaatagt cgggacaggt ttcttgatta gtttattgtt
    17701 tgagtgctta cagtatattt tagcaatagg tataacagat ataacggatt tgactttaaa
    17761 tacgctaggt gtctgtgtag gcttactgat ttatcaaatt tttataagag tgttcaaatc
    17821 acagactaga aaatggatca atatcttagg tatgcttagc cttggttttg cttatcttgt
    17881 tttactgtta ctgcatttaa ttggtgttta actaatgatt aaaaaggaga atataatgac
    17941 taaacgcgtc ttaatcagcg tctcagacaa agcgggcatt gttgaatttg cccaagaact
    18001 caaaaaactt ggttgggaga ttatctcaac aggtggaact aaggttgccc ttgataatgc
    18061 tggggtggat accattgcta tcgatgatgt gactggtttc ccagaaatga tggacggtcg
    18121 tgtgaagacc ctccacccaa atatccacgg agggcttctc gctcgtcgtg acttggatag
    18181 ccacttggaa gcggctaagg acaacaagat tgagctcatt gaccttgtgg tggtcaacct
    18241 ttacccattt aaggaaacta tccttaaacc agatgtgact tatgctgatg cagttgaaaa
    18301 tatcgatatt ggtgggccat ctatgcttcg ttcagcagcg aaaaatcatg ccagtgttac
    18361 agttgtggta gatcctgctg actacgctgt ggttttggac gaattggcag caaacggcga
    18421 aacctcttat gaaactcgcc aacgtttagc agccaaagta tttcgtcaca cagcggctta
    18481 tgacgccttg attgcaaaat acttcacagc tcaagtgggt gaaagcaagc ctgaaaaact
    18541 cactttgact tatgacctca agcaaccaat gcgttacggt gagaatcctc aacaagacgc
    18601 ggacttttac cagaaagctt tgcctacaga ttactccatt gcttcagcca aacagctcaa
    18661 cgggaaagaa ttgtcattta ataatatccg tgatgcagat gctgctatcc gtatcatccg
    18721 tgacttcaaa gatagtccaa ccgttgtggc tctcaaacac atgaatccat gtggaattgg
    18781 tcaagctgat gacatcgaga ctgcttggga atacgcttat gagtctgacc cagtgtctat
    18841 ctttggtgga attgtcgtcc tcaaccgtga ggtggatgct gcgacagctg agaagatgca
    18901 cggcgttttc ctcgaaatca tcattgcacc aagctatacg gatgaagcgc tagccatttt
    18961 gatcaataaa aagaaaaact tgcgtatcct tgccttgcca tttaatgctc aagaggctag
    19021 cgaagtggaa gcagaataca caggtgtagt cggtggactt ctcgtgcaaa atcaagacgt
    19081 ggtcaaggaa agcccagctg actggcaagt ggtgaccaaa cgtcagccaa ccgagacaga
    19141 agcgactgct cttgagttcg cttggaaggc tatcaagtac gtcaaatcaa atggcattat
    19201 cgtgaccaac gaccacatga cacttggtgt tggtccaggt caaaccaacc gtgtggcttc
    19261 tgttcgcctt gccattgacc aagccaaaga tcgtctggac ggggcggtcc ttgcttcaga
    19321 tgccttcttc ccatttgcgg ataacgtgga agaaatcgcc aaagcaggaa ttaaggccat
    19381 catccagccc ggtggctcag tccgtgacca agaatctatc gaagccgctg acaagtatgg
    19441 cttgaccatg gtcttcacag gagtgagaca ttttagacat taagaagata aaagggaaga
    19501 aaacagtttc tttccttttt tggcttaaaa tgctaactga aacaagatta aaacgaactt
    19561 ttttgatata atgttggtaa ataattcgca aaagaggttg aggaatgaaa ctgcttgttg
    19621 tcggttctgg tggtcgtgag catgcgattg ctaaaaagtt acttgaatca aaagacgtgg
    19681 aaaaagtctt tgtagctcct gggaatgatg ggatgactct ggatggtttg gaattggtaa
    19741 atatctctat ttccgaacat tctaaattga ttgacttcgc aaagaccaat gatgttgctt
    19801 ggacctttat cggcccagat gatgcccttg ctgctggtat cgtggatgat tttaaccaag
    19861 ctgggcttaa ggcctttggt ccgactaggg ctgcagcgga gctggagtgg tccaaggatt
    19921 ttgccaagga aatcatggtc aaatatggtg tttcgacagc agcctatggc acattttcag
    19981 attttgagga agcaaaggcc tatatcgaaa agcatggtgc gcctatcgta gtcaaggcgg
    20041 atggcttggc gcttgggaag ggtgtcgtcg ttgctgagac ggttgagcaa gcggtcgaag
    20101 ccgctcatga gatgcttttg gacaataaat ttggtgactc aggtgcgcgc gtggttattg
    20161 aggaattcct tgaaggagag gaattttcac tctttgcctt tgtcaatggt gataagttct
    20221 acatcatgcc aacggctcag gaccacaaac gtgcctacga tggcgacaaa gggcctaaca
    20281 cgggtggtat gggtgcctat gcgccagttc cacacttacc acagagtgta gttgatacag
    20341 cggttgacac cattgtcaag ccagttctag aagggatgat taaagaaggt cgcccttatc
    20401 tgggagttct ttacgcaggg cttatcctga cagctgatgg accgaaagtc atcgagttca
    20461 acgctcggtt cggagatcca gaaactcaga ttatcttgcc tcgcttgacc tctgactttg
    20521 ctcaaaatat cacagatatc ctggatagca aggagccaaa tatcacgtgg acggacaagg
    20581 gtgtgactct gggtgtggtt gtcgcatcca agggctaccc gctagattat tcaaagggtg
    20641 ttgagttgcc agtcaaaacc gatggtgaca tcattaccta ctatgcaggg gctaagtttg
    20701 cggaaaatag cagagcgctg ctctcaaacg gcggacgagt ttatatgctc gttaccacag
    20761 cagataccgt caaagaagcc caagccagca tctaccaaga actatcccaa caaaaaatag
    20821 aaggactctt ctaccgaaca gatatcggaa gcaaggcaat taagtaaaga tataagaata
    20881 acgcgacgca gtcgccaaac acgataatgg tcgtcgtggt gaaaagacca gaacagtgaa
    20941 tgttctggtc agggggaaac tttgagacct taggctcaaa gtttaggaat gaaaccgaag
    21001 gtttgcttcc gcctccatca cctaagacca ttatcaaaaa gaaaaataaa aattcacaaa
    21061 atacgttaat ggtcgtatgg tttgcgagcg ttagcgagct aatatggagc aattaccgcc
    21121 gttgtgaaag aacgattgga tgataatcca atcgttcagg gaaattggaa gaccttgggt
    21181 ttccaattta ggcatgagac acctttggtg gctgctgccg tccctcacaa gctaaggtga
    21241 ttgttgaaaa agaggaaaaa ggagaagaaa tgaaaccagt aatttccatc atcatgggct
    21301 caaaatccga ctgggcaacc atgcaaaaaa cagcagaagt cctagaccgc ttcggtgtag
    21361 cctacgaaaa gaaagttgtt tccgcacacc gtacaccaga cctcatgttc aaacatgcag
    21421 aagaagcccg tagccgtggc atcaagatca tcatcgcagg tgctggtggc gcagcccatt
    21481 tgccaggtat ggtcgctgct aaaacaatcc ttccagtcat tggtgtgcca gtcaactctc
    21541 gtgctcttag tggagtggat tcactctatt ctatcgttca gatgccgggt ggggtgcctg
    21601 ttgcgaccat ggctatcggt gaagcaggtg cgacaaatgc ggccctcttc gctctccgtc
    21661 tcctctcagt agaggatcag tctatcgcga cagcattggc agatttcgca gaagaacaag
    21721 gaaaaatcgc agaggagtcg tcaaatgagc tcatctaaaa caatcggaat tatcggtggc
    21781 ggtcaactgg gtcagatgat ggccatttct gctatctaca tggggcacaa ggttatcgcg
    21841 ctggatcctg cggcggattg cccggcctct cgcgtggcgg aaatcattgt ggcaccttat
    21901 aacgatgtgg acgccctccg tcagttggca gaccgttgcg atgtcctcac ttacgagttt
    21961 gaaaatgtcg acgctgacgg tttggatgtc gttatcaagg atggacaact ccctcaagga
    22021 acagatctgc tccgcatttc gcaaaatcgt atttttgaaa aggacttttt gtcaaacaag
    22081 gctcaagtca ctgtggcacc ctacaaggtc gtgacttcta gcctagactt ggcagatatc
    22141 gacttgtcga aaaactatgt ccttaagatc gcaacaggtg gttatgatgg acacgggcaa
    22201 aatgtcattc gttcagcaga cgatttggaa gaagcctatg cattagccga ctcagcagct
    22261 tgtgtcttgg aagaatttgt caattttgac cttgagattt ctgtcatcgt gtcaggaaat
    22321 gggaaggagg tgacgttttt cccagttcag gaaaatatcc accgcaacaa tatcctgtct
    22381 aagaccatcg taccagcccg tatttctgaa agtctagcag acaaggctaa agctatggca
    22441 gtgcgaatcg cagaacaact caacttgtct ggaactctct gtgtggaaat gtttgcgaca
    22501 gctgatgaca tcattgtcaa tgagattgct ccacgaccac acaactcagg ccactactct
    22561 attgaagcct gtgacttttc acaatttgac acgcatatat taggtgttct gggagcacca
    22621 ttgccagcca tcaaactaca tgcgcctgcc gtcatgctta acgttctcgg ccagcatgtt
    22681 gaggccgctg aaaaatatgt cacagaaaat ccaagcaccc acctccacat gtatggtaaa
    22741 atagaagcaa agcataatcg taagatggga catgtgactt tgtttagtga tgtaccggat
    22801 agtgtggaag agtttgggga agggattgat ttttaggaca agtctatgat acaaattatc
    22861 gttaatgcat ttattgaaaa ggataagact ggagcagttg ttgaagtgtt gtatgctagt
    22921 gctgaccaag ataaggtaca agctaaatat gaagaactag ctgcacaata ccccgaaaat
    22981 tatttagcta tctatgatgt accgctggat acggatttga atacactaga tcattacccg
    23041 tctgtgttta ttggaaaaga ggagtttgag tagaaatctt ggtttaccta gatagcttat
    23101 tcccaacagc ttaagaagaa aggaaagatt aacacatgat caaccgttac tctcgccctg
    23161 agatggcgaa tatttggagt gaagaaaata aataccgtgc ttggcttgag gtggaaatcc
    23221 tctctgacga ggcatgggct gagttggggg aaatccctaa ggaagatgtg gctttgattc
    23281 gcaagaaggc ggactttgac atcgaccgta ttttggaaat tgagcaggag acgcgccacg
    23341 atgtggtggc tttcacgcgt gcggtttctg agactcttgg tgaagagcgc aagtgggttc
    23401 actatgggtt aacttctacc gacgtggtgg atactgccta tggttacctc tacaagcagg
    23461 ccaacgacat catccgtcgt gaccttgaaa acttcactaa tatcatcgct gacaaggcca
    23521 aggagcacaa gttcaccatc atgatggggc gtactcatgg tgtgcacgct gagccgacaa
    23581 cttttggtct taaattggca acttggtata gcgaaatgaa acgcaatatc gagcgcttcg
    23641 agcatgcggc tgctggtgta gaagctggta agatttctgg tgcggttggg aactttgcca
    23701 atatcccacc atttgtagag gagtatgtct gcgataaact tggcatccgt gcccaagaaa
    23761 tctctacaca agtccttcct cgtgaccttc acgctgagta ctttgcggtt cttgccagca
    23821 ttgcgacttc aatcgaacgt atggcgactg agattcgtgg tctacaaaaa tctgagcaac
    23881 gcgaagtaga agagttcttt gctaaagggc aaaaagggtc ttcagcaatg cctcacaaac
    23941 gcaacccaat cggttctgaa aatatgactg gtctggcgcg tgtcattcgt ggtcacatga
    24001 ttacggctta tgaaaacgtc gctctctggc acgaacgcga tatttctcac tcatcagctg
    24061 agcgtatcat cacaccagat acgaccattt tgattgacta catgctcaac cgttttggaa
    24121 atatcgtcaa gaacttgaca gtcttcccag aaaatatgat ccgaaacatg aactcgactt
    24181 ttggtcttat ctttagccaa cgggctatgt tgacattgat tgaaaaaggc atgacccgtg
    24241 agcaagccta tgacttggtg caaccaaaaa cagcctactc ttgggacaac caagtagact
    24301 ttaaaccact tcttgaggca gattcagaag taacatcacg tctcactcaa gaagaaatcg
    24361 atgaaatctt caacccagtt tattacacca aacgagtgga tgatatcttt gaacgtcttg
    24421 gactaggtga ttaattaaaa aataaacagc gagcttcaat ctcgctgttt attttttatc
    24481 gaaaagactt agtcttcttt tcttttagtg agtccatagg ctgctagtgt ggacatgagt
    24541 cctgcgacta ctagtcctgc agaatcgtga gttcctgttt caggaagttt tttctctgtt
    24601 accacaggag ctggatcttg aggaagagct ttgctttcct cagcaggagc agttgatgga
    24661 gctggttggc ttgggatttc tagttttggt ttttcttcag caatagcggc ttgtccgttt
    24721 tcatcgccta catgtgttac catagttccg acttcgacta tttgagtaac ggcttcctgt
    24781 gctacgacac tatttacaag tgttttcact tccttaccat cggcagaagt gctcacagag
    24841 tagaagttgc tacgatgtcc attgacgccc ttagtaatga cttgtgtttt tcctttgagt
    24901 aagagtggat tttcacgagt cactgtggta aatggaattt cttctttttg gatatccagt
    24961 ctaggtttta cctcagtagt tggtgcaaga ccactttcat cacccttgtg agttacagga
    25021 gcgccaactt caaccacttg gtttataact tctttggtta cctggctatc aaggactgtt
    25081 tctgttgttt ttccattttc agtgagtaca gagatgtaat gagttcgttc acctttgact
    25141 cctgctgtga taatattttc ctgaccagct gggaggttag gattttcttt cttgataact
    25201 tcaaatggaa tttcttcagt tcttgtgatg agttctggtc tggtttcaac attggcagcc
    25261 acttcatttt catctaggct tcctgaatga gttgcagctg gtttgaggcc ttgaagagcg
    25321 gcttttaggt tggctacaag tgtgtcaagc tcagcttgtt tattacggtt gaggttgtaa
    25381 tttagagctg ttttagctgc gtcaagggcc tcaagacttt ctttactata tccttctaag
    25441 tttgtaggaa ttttagctaa ttcttcgcgg agagcattat aattagcacg gaagtagtct
    25501 ttgttgtggt ctgcaaaggc agtcatgagt tcaaagattt cctcttcctt gtactcagcg
    25561 cttggtctat ctgcccagat tgaaagcata cttccgactg ttggaagatc tacttcagga
    25621 tatttggtag aagctagttg attgaatggt gtttttccag tattctcaat agctttcttg
    25681 aggaaaccac caccatcttc tggtttttga ccaagaatgt agtaccagtc accgttggta
    25741 ttcaagaatt tatagccttt gcttgctagg tattgaggtg atgcgaggtt atatccccac
    25801 cagcctttag accagtaaga aatcaagaca tctttgtcaa actgaacatc gtccttgtct
    25861 tcatagtaga agccatcgtt gaaggccatt ggttgaagcc ctctttcttt ggccatagct
    25921 gcgagggtgt tggcatattc ggcaaatttg ccatagagtt gataccactt gaggtagtac
    25981 cagccttggg cactagtcgc atcgttggcg tattcgtcag taccaaagtt gaaaatcttt
    26041 gttttacctg caaagaagtc catgtattta ccgataaggg cttttacaaa gttcatcgct
    26101 tcttcgtttt tcaagtccat agttgttttt gaaactttat caaagtgggc ttgaggattt
    26161 ttaataccta atttttccat ggcaaccagc atagcatcca tgtgacctgg actgttaata
    26221 gctgggatga gaccgatgtc cttagattta gcgtattcaa ttagctctgt tacttctgcc
    26281 tgtgttagtg cagtaccgtt tggatcgtcg tagtaagctt tagttccttc gataatagct
    26341 tttttaacgt catcactagc ataggttttt ccgttggcag taatggtcat atcatcgagt
    26401 agaaagcgaa gtccgtcatt tcctagaagg agatggacat cagaatatcc gagctcactg
    26461 gccttgtcta cgatgcgttt gagctggttc agagtaaagt atttgcgtcc agcatcgatt
    26521 gagattacct tgtttttggc aagtttttca acctcacgtt tagcttcttc ttcttttaga
    26581 gcttcaggcg tgagggtcaa gttgttgaca gtttcttgaa gtttagcaat ggcttgatca
    26641 atcgtatctt gttgggcacg gctaaggttg ctatcgagag agcgaatagc tttttcagct
    26701 tcttttacgg ccgtgacgct ttctgcagta taacggttca ggtcttttgg tacctcgtta
    26761 agtgcttgct ctgcagattc ataatcagct gcgaagtatt cagcgttggc atttgcaaaa
    26821 tgacgcatga gtttgaagag gcgtgatggt gaataacgtg cagatggagt gtcagcccaa
    26881 gcagctacca taccaccgat gattgggata tcagctcctt ctgtttttgg tacagaagtg
    26941 attggtgtgt ttttaatacc attgagcccc tgatcgagat tgtaccagcc ttggccatca
    27001 gcgtttcgtc caagaacgta gtaccaagca tcattggtat taaggatttg gtgacctttt
    27061 tcagctagta gtttagaaga agcgacatcg tagcctcccc aaccaccagt ccacatagaa
    27121 acgatgatgt ctttgtcaaa actaccaaag cttgtgtcgc tattgtagta gataccgtcg
    27181 ttaaaagcca ttggtttgag accgtgcgat tttacaatac gagcgaggtc attggcgtag
    27241 gcaataaatt tttcatagcc ttttacaggg tagccttcgt ttggatagta tttatcagct
    27301 tgaagcacac tccaaccttt agcatctgtc gcatcattgg catattcatc aagtccgatg
    27361 ttgaagattt cagtcttttt cgcgaaataa gcagcatact tgtcgataag ggcttttgta
    27421 aaagcgacag cttgttcgtt gtcaagatcg acagtacggg ctgatttctt cccaaaatag
    27481 ctaaagttag ggttttggat tcccaattct ttcatggcat tgagaatcgc atccatgtgt
    27541 ccaggactat ttactgtcgg aatgagaccg atacctttat ctttggcata gttaatcaga
    27601 tctgtcattt gactttctgt taagtgattg ccgtttggat cgttgtaata atcatttgta
    27661 cctttttcaa tggcgcgttt gacatcgtca ctggcatagg tcttgccgtt agctgtgatg
    27721 ctcatatcgt ccaacatgaa acggagtcca tcatttccga ctaataggtg taaatcagtg
    27781 tagccataat gtttcgcttt atcgatgatt tccttgagtt gttctggtga gaaatattta
    27841 cgtccagcat caatagaaac aattttcttt ttcgctagtt tttcatttac agttgcagca
    27901 cgttcctttc ctgcctctgt ttccggtttg tcagcctctg ctttcgcttc atctttttta
    27961 gctggtttat ccttgtcagt cttgtctgta tttgactctt tagaatcaac ctctttcgct
    28021 tcttcctttt tagggctagc ttcttctgcc tttttattag cagtttcttt ttcagcagaa
    28081 gtttgagtta ccacctctgc tttatcacta ggagttgaac taacttcctc ttgtggtttt
    28141 tcttctgttt ttggaagact agctacctta tcagtagctg gagtttctgt ttctacagtt
    28201 tttggagctt ctggttgaag ctctgcttta ggtgtttcct cagtccgatt ttcggatgat
    28261 tgaggggaat cagaaactgt atggatggtc ggttggtttt ctgtagtagt agtaactcca
    28321 tcggctgcaa cagtctgtgc ttggaaggca aatccaatta gaacagaagc tgctcctaca
    28381 gcgtatttac gaatagaaaa acgctgttgt ttttcatgtt tcattgcaaa acctcctgat
    28441 tgcattgtta tattgatagc gattatataa atcaacgcct ttattttatt tcttatatta
    28501 acgagagtca agaggagatg acaaaaaact ataataagta taaaaaaata taaaatttaa
    28561 gcttaagatt tcagattggt cggaaaaaat acgtatatat atctagtata atttttggtt
    28621 ctatttctat aaaatattcc acaaattata gaatcttcca aaaataggta agcgctacct
    28681 ttttggtgtg gtataataag catagaaaaa gcccgagcga ttaggctcag gctttcttct
    28741 tagtgatcac ggtcacatga gatgaattta atcttgtagt aatcagatcg tttgtaagtt
    28801 tcactgtatt ctaaaacttg gccagttgat tcgagtttgg tgattttagt ttgtaggaca
    28861 gtagggaatt gttcatcgac tccgaggact gaagccgcat gttctggagt tggaaagact
    28921 atttcgttga tttcttcaaa gtgttcatca ttcatgtgaa tgtggtagtc taacttgaaa
    28981 cgattataga tagaactata gtattcaagg tttggataat ttgcgttgat atattgttct
    29041 gggatgtagg atgtatggta gatataaacg acaccgtttg attcgcggat acgttcaatc
    29101 ttgtagtaga attgatcgcc gcgtagaccc aatttttcca ggtaaacaag cttgtttccg
    29161 cgttcaattg aaagaacagt taccttatca tctttagcat tgaagagttc aatatctgaa
    29221 aactctacaa gcttgtgttt gcgtgcacgt gaaacgaagg ttccttttcc ttgttggcgg
    29281 acaatatagc catctttggc aaggtcgttt aaggcgcgaa caactgtgat agagctgaca
    29341 tcgtacattg aaatgagttc tgcttcagta taaaatttat ctccactgct aaactgccca
    29401 gagatgattt tattttttaa ttcgtctttt atgtattgat atttgggaat tgccatattt
    29461 ttacctctat tttccttctc catagaaaat tttaccataa aagcgaaaaa aatagtagtc
    29521 ttttgaataa aaaattagaa taatagtttg aaaaattaag ctatataggg attgatcata
    29581 ttttataaat gtattctata caaaattatt ttaggtccta tattccaaat ttaaagagcg
    29641 tttgaaatgg gtctaaaaat gtttgaaact aattgaatgt gtgtataata gtaaaaatgc
    29701 agtaaatatc ccgacaattt ctattgacag ttcaaacaga ttggtttata attaatataa
    29761 caacaaatga aagcgcaaac tttcgcggtc ggaaggtagt tttatgacac gatttgagat
    29821 acgagatgat ttctatctcg atggaaaatc atttaagatt ttatctggtg ccattcatta
    29881 ttttagggtt cctccagagg attggtatca ttcgctctat aacttgaagg ctcttggttt
    29941 taatacggta gagacttatg ttgcttggaa tttacacgag cctcgtgaag gtgagtttca
    30001 ttttgaaggt gatctggatt tagagaaatt tctccaaata gcgcaggatt tgggtctcta
    30061 cgcaattgtg cgtccgtctc catttatctg tgcggaatgg gaattcggtg gcttaccagc
    30121 ttggctcttg accaagaaca tgcgaattcg ctcatctgac ccagcatata tcgaggcagt
    30181 tggtcgctac tatgatcagt tattgccaag actggtgcct cgtttgttgg acaatggtgg
    30241 caatattctc atgatgcagg ttgaaaatga gtatggttct tacggagaag ataaggctta
    30301 cctgagagcg attcgacagc taatggaaga gtgtggcgta acctgtcccc tctttacatc
    30361 agatggtcca tggcgagcta ctctgaaagc tggaacctta attgaagagg acctctttgt
    30421 aacaggaaac tttggttcta aggcacctta caacttttcg cagatgcagg aattctttga
    30481 tgaacatggt aagaaatggc cactcatgtg tatggagttc tgggatggtt ggttcaatcg
    30541 ctggaaagaa ccgattatca cacgggatcc taaggaattg gcagatgcag ttcgagaggt
    30601 tttggaacaa ggctctatca atctttacat gttccacggt ggtacaaact ttggtttcat
    30661 gaatggttgc tcagctcgag gaactttgga cctgccacaa gttacgtctt atgattacga
    30721 tgcccttctg gatgaagaag gaaatccaac tgctaaatat cttgcagtca agaagatgat
    30781 ggcaacacat ttttcagagt atccgcagtt ggaaccactc tacaaagaga gtatggagtt
    30841 ggatgctatt ccactagttg aaaaagtttc tttgtttgaa accttagata gcttgtcaag
    30901 tcctgtagaa agtctctatc ctcaaaagat ggaggagctg ggacaaagtt atggctacct
    30961 actttatcga acagaaacaa actgggatgc agaagaagaa agacttcgta tcattgatgg
    31021 tcgagatagg gcccagctgt atgtcgatgg tcagtgggtt aaaactcaat atcagacaga
    31081 gattggggaa gatatttttt atcaaggtaa aaagaaaggg ctatctaggt tagatatctt
    31141 gatagaaaat atggggcgtg tcaactatgg gcataagttc ttagcggata cgcaacgtaa
    31201 gggaattcgg acaggggtct gtaaggatct gcatttctta ctaaactgga aacactatcc
    31261 actcccacta gacaatcctg agaaaattga tttttcaaaa ggatggactc aaggacaacc
    31321 agccttttac gcttatgact ttacagtcga agagccaaaa gatacttacc tagacttgtc
    31381 tgagtttggt aagggggttg cctttgtcaa tgggcagaat ctaggacgtt tttggaacgt
    31441 tggcccaact ctctcacttt atatccctca tagctatctc aaggaaggtg ccaaccgcat
    31501 cattatcttt gaaacagaag gtcaatataa agaagagatt catttaactc gtaaacctac
    31561 actaaaacat ataaaggggg aaaacttatg acaattgtag gatgccgtat tgatggacgt
    31621 ttgatccacg gacaagtagc caatctttgg gctggaaaac taaatgtttc acgcattatg
    31681 gttgtagacg acgaagttgt caacaacgat attgaaaaga gtggtttgaa acttgcgaca
    31741 ccaccaggtg tgaaattgag tattttgcca gttgagaaag ctgcagccaa tattcttgct
    31801 ggcaaatacg atagccaacg tctctttatc gtggctcgta aaccagaccg cttccttggt
    31861 ttggtagaag caggtgtacc acttgaaacc cttaatgttg ggaatatgtc tcaaacacca
    31921 gaaactcgtt ctattacacg ttctatcaac gtagtagaca aggatgtgga agacttccac
    31981 aaactggcag aaaaaggtgt taaacttact gctcagatgg ttccaaatga tccaatttca
    32041 gactttttga gcttattaaa ataggaaaaa aatttttagg aggtcattgt tatgatacaa
    32101 tggtggcaaa ttttacttct cactttgtac tcagcttatc aaatctgtga tgagttgacg
    32161 atcgtttcat ctgcaggttc ccctgtattt gctggtttca ttactggttt aatcatggga
    32221 gatgtgacta ctggtttact tatcggtggt aacttgcaac tgttcgttct tggggttggt
    32281 accttcggtg gtgcttctcg tatcgacgca acttctggtg cggttcttgc gacagccttc
    32341 tctgtttcac aaggaattga tgcaccgctt gccattacta caatcgctgt accagtagca
    32401 gctctcttga cttacttcga cgttcttggt cgtatgacta ctaccttctt cgctcaccgt
    32461 gtggatgctg caatcgaacg ctttgactat aaaggtattg aacgcaacta cttgcttggt
    32521 gcgattccgt gggctctatc tcgtgccctt ccagtcttct ttgcccttgc ttttggtggt
    32581 gcctttgtac aatcagtagt agacttcgtt gaagcctaca aatgggttgc agatggcttg
    32641 acacttgcag gacgtatgct tccaggtctt ggatttgcaa tcttgcttcg ttaccttcca
    32701 gttaaacgta accttcacta ccttgctatg ggatttggtt tgacagctat gttgactgtt
    32761 ctttactcat atgtaacagg tcttggtggc gctgttgctg gtatcgtagg tactcttcct
    32821 gctgaagttg ctgaaaaaat tggtttcgtg aacaacttca aaggtttgtc tatgattggt
    32881 atttctatcg taggtatttt ccttgcagtg cttcacttca aaaatagcca aaaagtagct
    32941 gtagcagcac cttctacacc atcagaaagt ggggaaatcg aagatgacga attctaatta
    33001 caaacttaca aaagaagatt ttaatcaaat caacaaacgt agcttgttta ctttccaatt
    33061 aggttggaac tacgaacgta tgcaagcttc tggttacctt tacatgatct tgcctcagtt
    33121 gcgtaaaatg tatggtgatg gaactcctga attgaaagaa atgatgaaag ttcatactca
    33181 attcttcaat acttcaccat tcttccatac cattatcgct ggttttgacc ttgccatgga
    33241 agaaaaagat ggtgtaggtt caaaagacgc cgttaacggt atcaagacag gtttgatggg
    33301 accattcgct cctcttgggg atacaatctt tggttcactt gtacctgcta tcatggggtc
    33361 agtcgcagca actatggcta tcgctggcca accttggggg atcttccttt ggattgcagt
    33421 tgcagtagcg tatgacatct tccgttggaa acagttggaa tttgcttaca aagaaggggt
    33481 taaccttatc aacaacatgc aaagtacctt gacagctttg attgacgctg catctgtact
    33541 tggtgtcttc atgatgggtg ctcttgtagc aacagtgatt aactttgaaa tttcttacaa
    33601 gttgccaatc ggtgaaaaga tgattgattt ccaagacatc ttgaaccaaa tcttcccacg
    33661 tttgcttcca gcaatcttta ctgcctttat cttctggttg cttggtaaga aaggtatgaa
    33721 ctctactaaa gctatcggta ttattatcgt acttgctttg gctctttctg cccttggtca
    33781 ctttgcactt ggaatgtaat tccttatgac taaatcatta attttggtga gccatggtcg
    33841 cttctgtgag gagcttagag gtagcacaga aatgattatg ggcccacaag acaacattta
    33901 cacagtagct cttcttccag aagatggccc agaagaattt actgctaaat ttgaagctgt
    33961 tattgaagga ttggatgatt tcctagtctt tgcggatctt ctcggtggga caccttgtaa
    34021 tgtggtgagt cgcttgatca tggaaggtcg tgatattgac ctttacgcag ggatgaatct
    34081 tccaatggtg attgaattta tcaatgcgag ccttacaggc gcagatgcgg actacaagag
    34141 ccgtgctgca gaaagcattg tgaaagttaa tgacctgtta gcgggcttcg atgatgacga
    34201 agatgaataa tactcttcga aaatctcttc aaactacgtc aacgtcgcct tgccgtaggt
    34261 atatgttact gacttcgtca gtcttatccg gcaacctcaa aacggtgttt tgagctgact
    34321 tcgtcagtct tatccggcaa cctcaaagca gtgctttgag cagcctgcgg ctagtttcct
    34381 acagatttta gttggaactc gattcaattc atgtgacaac gtgaaaatcg ttagagcatt
    34441 ttatatagaa tatacatggg aatgtagctt actcccattc ccatatttaa tagaaaaaga
    34501 ggaactcaat gctacattat acaaaagaag acttgctcga attgggtgca gaaatcacta
    34561 cgcgtgaaat ctaccaacag cctgatgtat ggagagaagc ttttgaattt tatcaagcaa
    34621 aacgtgaaga aattgcagcc ttcctacaag aaatcgctga taaacatgac tatattaagg
    34681 ttatcttgac aggtgctggg acttctgctt atgtgggaga taccttgcta ccttatttta
    34741 aggaagtcta tgacgaacgc aaatggaatt tcaatgctat tgcgacaaca gatatcgttg
    34801 ccaatccagc aacctatttg aaaaaagatg tggcaactgt ccttgtgtct tttgctcgta
    34861 gtgggaactc gcctgaaagt gtggcgactg ttgatttggc caaatccttg gtggatgagc
    34921 tttatcaagt gacgattact tgtgcagcag atggtaaatt ggctcttcaa gctcacggtg
    34981 atgaccgtaa tctcttgctc ttgcaaccag ctgtctctaa tgatgctgga tttgccatga
    35041 cttctagctt tacgtctatg atgttgacag ctctcttggt ctttgatcct acagaatttg
    35101 ctgttaagtc tgaacgtttt gaagttgtat ctagtcttgc ccgtaaagtt ttagacaagg
    35161 cagaagatgt caaagagctt gttgatttag actttaaccg tgtcatctat ctaggcgctg
    35221 gtcctttctt tggacttgct catgaagctc agctcaagat tttggaatta actgctggtc
    35281 aagttgcgac catgtatgaa agcccagttg gcttccgtca cggtccaaaa tctcttatca
    35341 acgacaatac agttgttttg gtctttggta caacgacaga ctacactcgt aagtatgact
    35401 tggacttggt tcgtgaagtt gctggtgacc agattgctcg tcgtgttgtg cttttgagtg
    35461 atcaagcttt tggtcttgaa aatgtcaaag aagtggccct tggttgtggc ggtgtcttga
    35521 atgatattta ccgtgtcttc ccttacatcg tttatgccca actctttgcc ctattgactt
    35581 cactcaaggt agaaaataaa ccagatacac cgtctcctac aggtacagta aaccgtgtag
    35641 tacaaggtgt cataattcac gaatatcaaa agtaagacag tgtttatgaa ttcttgacaa
    35701 gaggatttgt aaattatcag ataaaccata gattgtcagt acgctttcta tggtttgttt
    35761 gcttgagaga aatagtaaaa ggagaacaga atgaaagcat acacagagcg tgtatttgga
    35821 aatgttgagg gcgaggatgt cttggcctat cgatttgaga cagacggtgg ctaccaactt
    35881 gaggttatga cttatggcgc gaccatcttg cgctatgtcg cacctgacaa ggctggaaat
    35941 tttgccaatg ttatcttggg atttgatgac tttgatagtt atgtaggcaa tagtcccaag
    36001 catggagcaa gtgtaggtcc tgtagcgggt cgtattgcag gtgcgacctt tgagctcaat
    36061 ggtaagacct atgaccttga ggttaataat gctagcaact gtaatcacag tggttcaact
    36121 ggttgggatt ccagcttgtt tgaagttgaa gaagtaagcg atcatggctt gactctctac
    36181 acagagcgta cagatgggac aggagggttc cctggaaatc tcaagatttg gatcagttat
    36241 cacttggaag aaactggtgc ctatgaaatc agctacaagg taacgaccga tcaggatacg
    36301 ctggtcaatc caaccaacca cagctatttc aacttgtctg gtgatttcac gcagacgatt
    36361 gaccgtcatg tcttccaact aaacacagag ggcatttact caatcgctcc tgacggtgtt
    36421 cctgccaaaa ctccagaagc caaccgtgat gtggtcaaac acgtctacaa tggtaccttg
    36481 ttgaaggata tctttgcaga agaagatgag caaatccagc tggcatcagg tttggatcat
    36541 ccatttgccc ttcctgcagg ccatgacaat gctggattcc tttatgacca aaattcaggt
    36601 cgcttcctgc ttttcaagac agaagctcct tgctttgtgg tctacacagc aaactttgtg
    36661 gatgaaagtg tcatcatagg aggtcagcca atgctacagc acaatgggat tgctcttgaa
    36721 gcgcaagctt taccagatgc cattcacagt gaccttaaag gccaagtcat tcttaaggct
    36781 ggtcaaacct tcaccagtaa gacacgttat gaacttgttg tgaaataaaa aagctggtca
    36841 aaaagtcttt aaaattaaaa taacgcatat tgtcaggtga tgaaaagttt gatactatgc
    36901 gttttgttat gaaatgattt actttatctt atcctgaaat ggtgttattt ttgagttatc
    36961 tggcttgact ttcttgatgg aaattatata atagttgtaa caataataat tacaacgaga
    37021 aaagaggacc atttatgacc tatgaataca agagtcacat ttatttggca gagacagttt
    37081 taaatgtaaa ggatttggcc agtcaaacag ccttttatca gcaagttatt ggtttagaaa
    37141 tcttatctca aactgagaca gagtccattc taggccttgg tggaaaagtc ttggtacagc
    37201 tgattcaagc acaagagagc ggagaagtga gggaacatta tggtctttac catttggcca
    37261 ttctcttacc cacacgcaag gctttggctg atgtcttgaa acacctgaca gatttacaga
    37321 ttcctcttgt cggcggtgca gaccatggtt acagtgaagc tatttacttg gaagatttgg
    37381 agggaaatgg cattgaactc tatcgagata agccagtttc cacatgggat attcgagaag
    37441 atggacgcat tatcggagtg acggaggctc ttgcggcgca ggacatttat gagttggggg
    37501 aaagagtaga gccctttatc ctggcagaag gtacgagaat ggggcatatt catctttcag
    37561 tcaaggatag tcgaaagtcc agccagtttt atcaaaaggt gttagggcta gaggataaat
    37621 tcagtgtgcc tagcgctagt tggattgcgg ctggagatta ccatcatcat ttagcagtta
    37681 acgaatgggg aggaaaaggt ctggcttcgc gtaagcaagg cttaccaggt ttagcctact
    37741 atgtcatcga agtcgcacat aaaaaagaac tgttaacgat tgcccaacga gcacaagaag
    37801 ttgacgcacc aatcaaatgg atgacatcga gccaattgga aatcacagac tcagatggca
    37861 tcgtgacctg tattcgttta gcaaggtaaa attaggaatt tttaataagt tataagtatt
    37921 gctagtttgc tttttgaacg gtctttggta acagaactgc gtgagctgga tgggtgagaa
    37981 ttttgacaaa gaagctgatt agagatataa tgaagaaaaa tcgagcaagg aaaaagaaat
    38041 gacaaattca aagtatatta ctcgtttgaa acgttcagag ggccagttgc gtgggattca
    38101 aaagatgatt gaaggagatc gtgacgcaac tgacagcagt gagatctagt gtagagcgcg
    38161 tgattgagat gataattacc gaaaatctta ctgaatgtat caatcagcca ctagatgatt
    38221 ctgaagctca aaaggaacgc ctagaaaagg ctatccgata cttgattaaa cggaaataaa
    38281 tgaatgtttt gagacgatat gtgcaaaggt ctattaacta ttagaatagt ttaatgtgag
    38341 tcaaaagaag ttgtaaaaaa tctttaaaat taaaaaaacg catagtatca ggtgttgaat
    38401 gtactgaccc c
//
LOCUS       DAVBOG010000017        37881 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.017, whole genome shotgun sequence.
ACCESSION   DAVBOG010000017 DAVBOG010000000
VERSION     DAVBOG010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37881)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37881)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37881
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.017"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..399
                     /locus_tag="VQ865_000915"
     CDS             <1..399
                     /locus_tag="VQ865_000915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3135272.1"
                     /translation="SEIIAYNLSTSPNLEQVQTMLEQAFTEKHYENTILHSDQGWQYQ
                     HDSYHRFLESKGIQASMSRKGNSQDNGMMESFFGILKSEMFYGYEKSFQSLKQLEQAI
                     IDYIDYYNNKRIKVKLKGLSPVQYRTKSFG"
     gene            complement(444..1085)
                     /gene="plsY"
                     /locus_tag="VQ865_000916"
     CDS             complement(444..1085)
                     /gene="plsY"
                     /locus_tag="VQ865_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HET3135273.1"
                     /translation="MITIVLLILAYLLGSIPSGLWIGQVFFQINLREHGSGNTGTTNT
                     FRILGKKAGMATFVIDFFKGTLATLLPIIFHLQGVSPLIFGLLAVIGHTFPIFAGFKG
                     GKAVATSAGVIFGFAPIFCLYLAIIFFGALYLGSMISLSSVTASIAAVIGVLLFPLFG
                     FILSNYDSLFIAIILALASLIIIRHKDNIARIKNKTENLVPWGLNLTHQDPKK"
     gene            1221..3164
                     /gene="parE"
                     /locus_tag="VQ865_000917"
     CDS             1221..3164
                     /gene="parE"
                     /locus_tag="VQ865_000917"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HET3135274.1"
                     /translation="MSKKEININNYNDDAIQVLEGLDAVRKRPGMYIGSTDGAGLHHL
                     VWEIVDNAVDEALSGFGDRIDVTINKDGSLTVQDHGRGMPTGMHAMGIPTVEVIFTIL
                     HAGGKFGQGGYKTSGGLHGVGSSVVNALSSWLEVEITRDGAVYKQRFENGGKPVTTLK
                     KIGTAPKSKTGTKVTFMPDATIFSTTDFKYNTISERLNESAFLLKNVTLSLTDKRTDE
                     AIEFHYENGVQDFVSYLNEDKEILTPVLYFEGEDNGFQVEVALQYNDGFSDNILSFVN
                     NVRTKDGGTHETGLKSAITKVMNDYARKTGLLKEKDKNLEGSDYREGLAAVLSILVPE
                     EHLQFEGQTKDKLGSPLARPVVDGIVADKLTFFLMENGELASNLIRKAIKARDAREAA
                     RKARDESRNGKKNKKDKGLLSGKLTPAQSKNPAKNELYLVEGDSAGGSAKQGRDRKFQ
                     AILPLRGKVINTAKAKMADILKNEEINTMIYTIGAGVGADFSIEDANYDKIIIMTDAD
                     TDGAHIQTLLLTFFYRYMRPLVEAGHVYIALPPLYKMSKGKGKKEEVAYAWTDGELEE
                     LRKQFGKGATLQRYKGLGEMNADQLWETTMNPETRTLIRVTIEDLARAERRVNVLMGD
                     KVEPRRKWIEDNVKFTLEEATVF"
     gene            3584..6055
                     /gene="parC"
                     /locus_tag="VQ865_000918"
     CDS             3584..6055
                     /gene="parC"
                     /locus_tag="VQ865_000918"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HET3135275.1"
                     /translation="MSNIQNMSLEDIMGERFGRYSKYIIQDRALPDIRDGLKPVQRRI
                     LYSMNKDSNTFDKSYRKSAKSVGNIMGNFHPHGDSSIYDAMVRMSQNWKNREILVEMH
                     GNNGSMDGDPPAAMRYTEARLSEIAGYLLQDIEKNTVPFAWNFDDTEKEPTVLPAAFP
                     NLLVNGSTGISAGYATDIPPHNLAEVIDAAVYMIDHPTAKIDKLMEFLPGPDFPTGAI
                     IQGRDEIKKAYETGKGRVVVRSKTEIEKLKGGKEQIVITEIPYEINKANLVKKIDDVR
                     VNNKVAGIAEVRDESDRDGLRIAIELKKDANTELVLNYLFKYTDLQINYNFNMVAIDN
                     FTPRQVGIVPILSSYIAHRREVILARSRFDKEKAEKRLHIVEGLIRVISILDEVIALI
                     RASENKADAKENLKVSYDFTEEQAEAIVTLQLYRLTNTDVVVLQEEEAELREKIAMLA
                     AIIGDERTMYNLMKKELREVKKKFATPRLSSLEDTAKAIEIDTASLIAEEDTYVSVTK
                     AGYIKRTSPRSFAASTLEEIGKRDDDRLIFVQSAKTTQHLLMFTSLGNVIYRPIHELA
                     DIRWKDIGEHLSQTITNFETNEEILYVEVLDQFDDATTYFAVTRLGQIKRVERKEFTP
                     WRTYRSKSVKYAKLKDDTDQIVAVAPIKLDDVVLVSQNGYALRFNIEEVPVVGAKAAG
                     VKAMNLKEDDVLQSGFICNTSSFYLLTQRGSLKRVSIEEILATSRAKRGLQVLRELKN
                     KPHRVFLAGAVAEQGFVGDFFSTEVDVNDQTLLVQSNKGTIYESRLQDLNLSERTSNG
                     SFISDTISDEEVFDAYLQEVVTEDK"
     gene            6187..7209
                     /locus_tag="VQ865_000919"
     CDS             6187..7209
                     /locus_tag="VQ865_000919"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HET3135276.1"
                     /translation="MTVTIDWENLGFSYMKLPYRYLAHFKNGQWDQGELTEDATLHIS
                     ESSPSLHYGQQAFEGLKAYRTKDGSVQLFRPDENAKRLQRTCDRLLMPQVPTDMFVEA
                     CKAVVRANEEYVPPYGTGGTLYLRPLLIGVGDIIGVKPAEEYIFTIFAMPVGNYFKGG
                     LVPTNFLIQDEYDRAAPNGTGAAKVGGNYAASLLPGKMAKSRHFSDVIYLDPSTHTKI
                     EEVGSANFFGITADNEFVTPLSPSILPSITKYSLLYLAEHRLGLTPIEGDVPIDNLDR
                     FVEAGACGTAAVISPIGGIQHGDDFHVFYSETEVGPVTRKLYNELTGIQFGDIEAPEG
                     WIVKVD"
     gene            7265..7969
                     /locus_tag="VQ865_000920"
     CDS             7265..7969
                     /locus_tag="VQ865_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135277.1"
                     /translation="MVLSTSAILVACGKTDKEADAPTTFSYVYAVDPASLGYSIATRT
                     SRTDVIGNVIDGLMENDKYGNVAPSQKDYDLNGTGWAPSYQDPASYLNIMDPKSGSAM
                     KHLGITKGKDKDVVAKPGLDKYKKLLEDAVSETTDLEKRYEKYAKAQAWSTDSSLLMP
                     TASSGGFPVVSNVVPFSKPYSQVGIKGEPYIFKGMKLQKDIVTTKEYNEVFKKWQKEK
                     LESNSKYQKELEKYIK"
     gene            8034..8723
                     /locus_tag="VQ865_000921"
     CDS             8034..8723
                     /locus_tag="VQ865_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000454813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HET3135278.1"
                     /translation="MEWIRLIGIAIIVVGFILKFDTIATVVLAGLVTALVSGVSLVEF
                     LEILGKEFSNQRVLTIFMVTLPLVGLSETFGLKQRSIDLIRKIKGLTVGNFYTVYFFI
                     RELAGFFSIRLGGHPQFVRPLVQPMGEAAAESQLGRKLTEVEDETIKARAAANENFGN
                     FFAQNTFVGAGGVLLIGGTLDQLGYESNYAGIASTSIIVAVITLIVVGIYNYLFDKKL
                     ISKKTRGGEQK"
     gene            8720..9643
                     /locus_tag="VQ865_000922"
     CDS             8720..9643
                     /locus_tag="VQ865_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000137271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HET3135279.1"
                     /translation="MTELAKQLLELTYIVIGCQFLHTAYCSYKDKTNPVRLGTSAFWT
                     LLSITFIGGSYMPNMSIGIIVILLSLLTLFKQVRIGTLPSLDEMKANIESNRLKNKIF
                     IPVMLMAILALVLAQMIPEFSKISISLAALFATISVLVITNSHPKSLLSENNRMTQQV
                     STSGIVPQLLGALGAIFTVAGVGDVISHLISGIVPSDSRFIGVLAYVLGMVLFTMIMG
                     NAFAAFTVITAGVGVPFVFALGANPIVAGALAMTAGYCGTLLTPMAANFNALPAALMD
                     MKDQNGVIKAQAGVALVMIVIHIFLMYFLAF"
     gene            9658..10302
                     /gene="pcp"
                     /locus_tag="VQ865_000923"
     CDS             9658..10302
                     /gene="pcp"
                     /locus_tag="VQ865_000923"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HET3135280.1"
                     /translation="MKILVTGFNPFGGEKINPALEAVKLLPSEINGAEVRWVEIPTVF
                     YKSSEVLEAEILRYQPDAVLCIGQAGGRTGLTPERVAINQDDARIPDNEGNQPIDTPI
                     RIDGASAYFSSLPIKAMVQAIKKQGLPAVVSNSAGTFVCNHLMYQALYLVDKKFPNMR
                     AGFMHIPYMMEQVVNKPNTAGMSLCDIVRGIEVAIEAIVDYKDKDLQLVGGETH"
     gene            10470..10700
                     /locus_tag="VQ865_000924"
     CDS             10470..10700
                     /locus_tag="VQ865_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000037109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HET3135281.1"
                     /translation="MSKKDKKIEIQVADAKVNVGKDSFEGYTLTIGKKVIGEIAELDG
                     QFAIIKNGNVDSFYKKLEKAVEILIENYNLAK"
     gene            10750..10830
                     /locus_tag="VQ865_000925"
     tRNA            10750..10830
                     /locus_tag="VQ865_000925"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10784..10786,aa:Tyr,seq:gta)
     gene            10840..10911
                     /locus_tag="VQ865_000926"
     tRNA            10840..10911
                     /locus_tag="VQ865_000926"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:10872..10874,aa:Gln,seq:ttg)
     gene            11073..12275
                     /gene="rpsA"
                     /locus_tag="VQ865_000927"
     CDS             11073..12275
                     /gene="rpsA"
                     /locus_tag="VQ865_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002897515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HET3135282.1"
                     /translation="MNEFEDLLNSVSQVETGDVVSAEVLTVDATQANVAISGTGVEGV
                     LTLRELTNDRDADINDFVKVGEVLDVLVLRQVVGKDTDTVTYLVSKKRLEARKAWDKL
                     VGREEEVVTVKGTRAVKGGLSVEFEGVRGFIPASMLDTRFVRNAERFVGQEFDTKIKE
                     VNAKENRFILSRREVVEAATAAARAEVFGKLAVGDVVTGKVARITSFGAFIDLGGVDG
                     LVHLTELSHERNVSPKSVVTVGEEIEVKILDLNEEEGRVSLSLKATVPGPWDGVEQKL
                     AKGDVVEGTVKRLTDFGAFVEVLPGIDGLVHVSQISHKRIENPKEALKVGQEVQVKVL
                     EVNADAERVSLSIKALEERPAQEEGQKEEKRAARPRRPRRQEKRDFELPETQTGFSMA
                     DLFGDIEL"
     gene            12361..12858
                     /locus_tag="VQ865_000928"
     CDS             12361..12858
                     /locus_tag="VQ865_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HET3135283.1"
                     /translation="MLKSEKQSRYQMLNEELSFLLEGETNVLANLSNASALIKSRFPN
                     TVFAGFYLFDGKELVLGPFQGGVSCIRIALGKGVCGEAAHFQETVIVGDVTTYLNYIS
                     CDSLAKSEIVVPMMKNGQLLGVLDLDSSEIEDYDAMDRDYLEQFVAILLEKTTWDFTM
                     FEEKS"
     gene            12858..14513
                     /gene="dnaX"
                     /locus_tag="VQ865_000929"
     CDS             12858..14513
                     /gene="dnaX"
                     /locus_tag="VQ865_000929"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HET3135284.1"
                     /translation="MYQALYRKYRSQNFSQLVGQEVVAKTLKQAVEQEKISHAYLFSG
                     PRGTGKTSVAKIFAKAMNCPNQVGGEPCNNCYICQAVTDGSLEDVIEMDAASNNGVDE
                     IREIRDKSTYAPSLARYKVYIIDEVHMLSTGAFNALLKTLEEPTQNVVFILATTELHK
                     IPATILSRVQRFEFKSIKTQDIKEHIHYILEKENISSEPEAVEIIARRAEGGMRDALS
                     ILDQALSLTQGNELTTAISEEITGTISLSALDDYVAALSQQDVPKALSCLNLLFDNGK
                     SMTRFVTDLLHYLRDLLIVQTGGENTHHSSVFVENLALPQKNLFEMIRLATVNLADIK
                     SSLQPKIYAEMMTVRLAEIKPEPALSGAVENEIATLRQEVARLKQELSNAGAVPKQVA
                     PAPSRPATGKTVYRVDRNKVQSILQEAVENPDLARQNLIRLQNAWGEVIESLGGPDKA
                     LLVGSQPVAANEHHAILAFESNFNAGQTMKRDNLNTMFGNILSQAAGFSPEILAISME
                     EWKEVRAAFSAKAKSSQTEKEVEESLIPEGFEFLADKVKVEED"
     gene            14541..14735
                     /locus_tag="VQ865_000930"
     CDS             14541..14735
                     /locus_tag="VQ865_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3272 domain-containing protein"
                     /protein_id="HET3135285.1"
                     /translation="MNKQQFIIMALFTAAETYFFNEAWMTGRYIMAAFWAILLFRNFR
                     VSYVMGKIVDVIDQHFNRKD"
     gene            14885..15655
                     /gene="sufC"
                     /locus_tag="VQ865_000931"
     CDS             14885..15655
                     /gene="sufC"
                     /locus_tag="VQ865_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000114488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HET3135286.1"
                     /translation="MSVIEIKDLHVEIEGKEILKGVNLTLKTGEIAAIMGPNGTGKST
                     LSAAIMGNPNYEVTKGEVLFDGVNILELEVDERARMGLFLAMQYPSEIPGITNAEFLR
                     AAMNAGKEDDEKISVREFITKLDEKMELLNMKEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFALLDEIDSGLDIDALKVVSKGVNAMRGEGFGAMIITHYQRLLNYITPDVVHV
                     MMEGRVVLSGGPELAARLEREGYAKLAEELGYDYKEEL"
     gene            15683..16945
                     /gene="sufD"
                     /locus_tag="VQ865_000932"
     CDS             15683..16945
                     /gene="sufD"
                     /locus_tag="VQ865_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HET3135287.1"
                     /translation="MTRENIKLFSEMHAEPSWLADLRQKAFDKIETLELPVIERVKFH
                     RWNLGDGTITENEPSANVPDFTALDHHLKLVQVGTQTVFEQTPVELAEQGVVFTDFHS
                     ALEEIPELIEEFFMSSVKYDDDKLAAYHTAYFNSGAVLYIPDNVEITEPIEGIFYQDS
                     DSNVPFNKHIMIIAGKNSKISYLERLESRGEGSDKATANITVEVIAHSGAQVKFAAID
                     RLGENVTAYISRRGKLGNDASIDWAIGVMNEGNVVADFDSDLIGNGSYADLKVVALSS
                     GRQVQGIDTRVTNYGCNSIGNILQHGVILEKATLTFNGIGHIIKGAKGADAQQESRVL
                     MLSDQARSDANPILLIDENDVTAGHAASIGQVDPEDMYYLMSRGLDKATAERLVVRGF
                     LGSVIVEIPVKEVRDEMIATIEEKLSKR"
     gene            16956..18182
                     /locus_tag="VQ865_000933"
     CDS             16956..18182
                     /locus_tag="VQ865_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3135288.1"
                     /translation="MLDVEAIRKDFPILDQIVNDEPLVYLDNAATTQKPLVVLKAINS
                     YYEQDNANVHRGVHTLAERATASYEAARETIRKFINAGSTKEVLFTRGTTTSLNWVAR
                     FAEEILTEGDQVLISVMEHHSNIIPWQEACRKTGAELVYVYLKDGALDMEDLRAKLTD
                     KVKFVSLAHASNVLGVVNPIKEITQLAHQVGAIMVVDGAQSTPHMKIDVQDLDLDFFA
                     FSGHKMAGPTGIGVLYGKEKYLEQMSPVEFGGEMIDFVYEQSASWKELPWKFEAGTPN
                     MAGAIGLATAVDYLEKIGMDAVEAHEQELIAYVYPKLQAIEGLTIYGSQDLAQRSGVI
                     AFNLGDLHPHDLATALDYEGVAVRAGHHCAQPLLQYLEVSATARASFYIYNTKADCDK
                     LVDALQKTKEFFNGTF"
     gene            18169..18609
                     /locus_tag="VQ865_000934"
     CDS             18169..18609
                     /locus_tag="VQ865_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HET3135289.1"
                     /translation="MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVI
                     NLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQ
                     KDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ"
     gene            18663..20075
                     /gene="sufB"
                     /locus_tag="VQ865_000935"
     CDS             18663..20075
                     /gene="sufB"
                     /locus_tag="VQ865_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HET3135290.1"
                     /translation="MAEERVEPKPIDLGEYKFGFHDDVEPVLSTGKGLNEGVIRELSA
                     AKGEPEWMLEFRLKSYETFKKMPMQTWGADLSEIDFDDLIYYQKPSDKPARSWDDVPE
                     KIKETFERIGIPEAERAYLAGASAQYESEVVYHNMKEEFQKLGIIFTDTDSALKEYPD
                     LFNQYFAKLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDIPLQTYFRINNENIGQFE
                     RTLIIVDEGASVHYVEGCTAPTYSSNSLHAAIVEIFALDGAYMRYTTIQNWSDNVYNL
                     VTKRAKAQKDATVEWIDGNLGAKTTMKYPSVYLDGEGARGTMLSIAFANAGQHQDTGA
                     KMIHNAPHTSSSIVSKSIAKGGGKVDYRGQVTFNKNSKKSVSHIECDTIIMDDLSASD
                     TIPFNEIHNSQVALEHEAKVSKISEEQLYYLMSRGLSESEATEMIVMGFVEPFTKELP
                     MEYAVELNRLISYEMEGSVG"
     gene            complement(20274..21515)
                     /locus_tag="VQ865_000936"
     CDS             complement(20274..21515)
                     /locus_tag="VQ865_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HET3135291.1"
                     /translation="MKKIFLTLLTVSLLGGVSTAVAQDFTIAAKHAIAVEANTGKILY
                     EKDATQPVEIASITKLITVYLVYEALENGSITLSTPVDISDYPYQLTTNSEASNIPME
                     ARNYTVEELLEATLVSSANSAAIALAEKIAGSEKDFVDMMRAKLLEWGIQDATVVNTT
                     GLNNETLGDNIYPGSKKDEENKLSAYDVAIVARNLIKKYPQVLEITKKPSSTFAGMTI
                     TSTNYMLEGMPAYRGGFDGLKTGTTDKAGESFVGTTVEKGMRVITVVLNADHQDNNPY
                     ARFTATSSLMDYISSTFTLRKIVQQGDAYQDSKAPVQDGKEDTVTAVAPEDIYLIERV
                     GNQSSQSVQFTPDSKAIPAPLEAGTVVGHLTYEDKDLIGQGYITTERPSFEMVADKKI
                     EKAFFLKVWWNQFVRFVNEKL"
     gene            21618..22727
                     /locus_tag="VQ865_000937"
     CDS             21618..22727
                     /locus_tag="VQ865_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3135292.1"
                     /translation="MFRRNKLFFWTTEILLLTIIFYLWRQMGSLINPFVSVLNTIMIP
                     FLLGGFLYYLTNPIVTFLNKVCKLNRLLGILITLCTLVWGMVIGVVYLLPILINQLSS
                     LIISSQTIYSRVQDLIIDLSNYPALQNLDVEATIQQLNLSYVDILQNILNSVSNSVGS
                     VLSALISTVLILIMTPVFLVYFLLDGHKFLPMLERTILKRDRLHIAGLLKNLNATIAR
                     YISGVSIDAIIIGCLAYIGYSIIGLKYALVFAIFSGVANLIPYVGPSIGLIPMIIANI
                     FTDPHRLLIAVIYMLVVQQVDGNILYPRIVGSVMKVHPITILVLLLLSSNIYGVVGMI
                     VAVPTYSILKEISKFLSRLYENHKIMKERERELAK"
     gene            23373..23720
                     /gene="ssrA"
                     /locus_tag="VQ865_000938"
     tmRNA           23373..23720
                     /gene="ssrA"
                     /locus_tag="VQ865_000938"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(23903..23990)
                     /locus_tag="VQ865_000939"
     tRNA            complement(23903..23990)
                     /locus_tag="VQ865_000939"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23954..23956),aa:Ser,seq:gga)
     gene            24152..24892
                     /locus_tag="VQ865_000940"
     CDS             24152..24892
                     /locus_tag="VQ865_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3135293.1"
                     /translation="MLKTERKQLILEELNQHHVVSLEKLVSLLETSESTVRRDLDELE
                     AENKLRRVHGGAELPHSLQEEETIQEKSVKNLQEKKLLAQKAASLIKEKDVIFIDAGT
                     TTAFLIHELVNKNVTVVTNSIHHAAQLVEKQIPTVMVGGNVKTATDASIGGVALNQIN
                     QLHFDRAFIGMNGVDDGYYTTPDMEEGAVKRAILENAKQTYVLVDSSKIGQTCFAKVA
                     PLKRAIVITSQGHELLQVIKEKTEVIEV"
     gene            24889..25800
                     /gene="pfkB"
                     /locus_tag="VQ865_000941"
     CDS             24889..25800
                     /gene="pfkB"
                     /locus_tag="VQ865_000941"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HET3135294.1"
                     /translation="MIYTVTLNPSIDYIVRLDQVKVGSVNRMDSDDKFAGGKGINVSR
                     VLKRLNIPNTATGFIGGFTGKFITDTLAEEEIETRFVQVAEDTRINVKIKADQETEIN
                     GTGPTVEPVQLEELKAILSSLTAEDTVVFAGSSAKNLGNVIYKDLISLTRQTGAQVVC
                     DFEGQTLIDSLDYQPLLVKPNNHELGAIFGVKLESLDEIEKYARELLAKGAQNVIISM
                     AGDGALLVTSEGAYFAKPIKGTVKNSVGAGDSMVAGFTGEFVKSKDAVEAFKWGVACG
                     TATTFSDDLATAEFIKETYGKVEVEKR"
     gene            25797..27749
                     /locus_tag="VQ865_000942"
     CDS             25797..27749
                     /locus_tag="VQ865_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3135295.1"
                     /translation="MKIQDLLRKDVMLLDLQATEKTAVIDEMIKNLTEHGYVTDFETF
                     KEGILAREALTSTGLGDGIAMPHSKNAAVKEATVLFAKSNKGVDYESLDGQATDLFFM
                     IAAPEGANDTHLAALAELSQYLMKDGFADKLRQATSADQVIELFDQASEKTEELVQAP
                     ANDSGDFIVAVTACTTGIAHTYMAQEALQKVAAEMGVGIKVETNGASGVGNQLTAEDI
                     RKAKAIIIAADKAVEMDRFDGKPLINRPVADGIRKTEELINLALSGDTEVYRAANGAK
                     AATASNEKQSLGGALYKHLMSGVSQMLPFVIGGGIMIALAFLIDGALGVPNENLGNLG
                     SYHELASMFMKIGGAAFGLMLPVFAGYVAYSIAEKPGLVAGFVAGAIAKEGFAFGKIP
                     YAAGGEATSTLAGVSSGFLGALVGGFIAGALVLAIKKYVKVPRSLEGAKSILLLPLLG
                     TILTGFVMLAVNIPMAAINTAMNDFLGGLGGGSAVLLGIVLGGMMAVDMGGPVNKAAY
                     VFGTGTLAATVSSGGSVAMAAVMAGGMVPPLAIFVATLLFKDKFTKEERNSGLTNIIM
                     GLSFITEGAIPFGAADPARAIPSFILGSAVAGGLVGLTGIKLMAPHGGIFVIALTSNA
                     LLYLVSVLVGAIVSGVVYGYLRKPQA"
     gene            27913..30138
                     /locus_tag="VQ865_000943"
     CDS             27913..30138
                     /locus_tag="VQ865_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3135296.1"
                     /translation="MLISLGIAILLIFAAFKLGAAGITLYNLIRLLVGSLAYLAIFGL
                     LIYLFFFKWIRKQEGLLSGFFTIFAGLLLIFEAYLVWKYGLDKSVLKGTMAQVVTDLT
                     GFRTTSFAGGGLIGVALYIPTAFLFSNIGTYFIGSILILVGSLLVSPWSVYDIAEFFS
                     RGFAKWWEGHERRKEERFVKQEEKARQKAEKEARLEQEETEKALLDLPPVDMETGEIL
                     TEEAVQNLPPIPEEKWVEPEIILPQAELKFPEQEDDSDDEDVQVDFSAKEALEYKLPS
                     LQLFAPDKPKDQSKEKKIVRENIKILEATFASFGIKVTVERAEIGPSVTKYEVKPAVG
                     VRVNRISNLSDDLALALAAKDVRIEAPIPGKSLIGIEVPNSDIATVSFRELWEQSQTK
                     AENFLEIPLGKAVNGTARAFDLSKMPHLLVAGSTGSGKSVAVNGIIASILMKARPDQV
                     KFMMVDPKMVELSVYNDIPHLLIPVVTNPRKASKALQKVVDEMENRYELFAKVGVRNI
                     AGFNAKVEEFNSQSEYKQIPLPFIVVIVDELADLMMVASKEVEDAIIRLGQKARAAGI
                     HMILATQRPSVDVISGLIKANVPSRVAFAVSSGTDSRTILDENGAEKLLGRGDMLFKP
                     IDENHPVRLQGSFISDDDVERIVNFIKTQADADYDESFDPGEVSENEGEFSDGDAGGD
                     PLFEEAKSLVIETQKASASMIQRRLSVGFNRATRLMEELEIAGVIGPAEGTKPRKVLQ
                     Q"
     gene            complement(30291..30719)
                     /locus_tag="VQ865_000944"
     CDS             complement(30291..30719)
                     /locus_tag="VQ865_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135297.1"
                     /translation="MSNYRRTSKPKTEHIKKGFTVFQKTITTIGSILGLITAGITIMN
                     ALDNNNKNTKKEPTTSQTTTFVKEIQKESPQENTTPNKENNTSQEKTQQEETPKSSVK
                     EEKKEDQKTATQDSTTPATSKPATENEKQPNTPTSENNTQ"
     gene            30857..31999
                     /locus_tag="VQ865_000945"
     CDS             30857..31999
                     /locus_tag="VQ865_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000638948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3135298.1"
                     /translation="MIYFDNSATTRPYPEALETYMQVASKILGNPSSLHRLGDQATRI
                     LDASRQQIADLIGKKSDEIFFTSGGTEGDNWIIKGVAFEKAQFGKHIIVSAIEHPAVK
                     ESALWLKAQGFEVDFAPVDNKGFVDVEALEDLIRPDTTLVSIMAVNNEIGSIQPIEAI
                     SEFLADKPTISFHVDAVQALAKIPTEKYLTERVDFATFSGHKFHGIRGVGFIYIKSGK
                     KITPLLTGGGQERDYRSTTENVAGIAATAKALRLSMEKLDIFRSKTGQMKAVIRQALL
                     DYPDIFVFSDEEDFAPHILTFGIKGVRGEVIVHAFEDYDIFISTTSACSSKAGKPAGT
                     LIAMGVDKDKAQSAVRLSLDLENDMSQVEQFLTKLKLIYNQTRKVR"
     gene            32008..33222
                     /gene="thiI"
                     /locus_tag="VQ865_000946"
     CDS             32008..33222
                     /gene="thiI"
                     /locus_tag="VQ865_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001200101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HET3135299.1"
                     /translation="MQYSEIMIRYGELSTKGKNRMRFINKLRNNISDVLSIYPQVKVT
                     ADRDRAHAYLNGADYTAVAESLKQVFGIQNFSPVYKVEKSVEVLKSAVQEIMQDIYKE
                     GMTFKISSKRSDHTFELDSRELNQTLGGAVFEAIPNVQAQMKSPDINLQVEIREEAAY
                     LSYETVRGAGGLPVGTSGKGMLMLSGGIDSPVAGYLALKRGVDIEAVHFASPPYTSPG
                     ALKKAQDLTRKLTKFGGNIQFIEVPFTEIQEEIKAKAPEAYLMTLTRRFMMRITDRIR
                     EVRNGLVIINGESLGQVASQTLESMKAINAVTNTPIIRPVVTMDKLEIIDIAQEIDTF
                     DISIQPFEDCCTIFAPDRPKTNPKIKNAEQYEARMDVEGLVERAVAGIMITEITPQAE
                     KDEVDDLIDNLL"
     gene            33357..34181
                     /locus_tag="VQ865_000947"
     CDS             33357..34181
                     /locus_tag="VQ865_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001076703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3135300.1"
                     /translation="MNQSYFYLKMKEHKLKVPYTGKERRVRILLPKDYEKDTDRSYPV
                     VYFHDGQNVFNSKESFIGHSWKIIPAIKRNPDISRMIVVAIDNDGMGRMNEYAAWKFQ
                     ESPIPEQQFGGKGVEYAEFVMEVVKPFIKHKTGWFDGMMTTGCSMGAYHALNFFLQHP
                     DVFTKVIALSGVYDARFFVGDYYNDDAIYQNSPVDYIWNQNDGWFIDRYRQAEIVLCT
                     GLGAWEQDGLPSFYKLKEAFDQKQIPAWFAEWGHDVAHDWEWWRKQMPYFLGNLYL"
     gene            34194..35360
                     /locus_tag="VQ865_000948"
     CDS             34194..35360
                     /locus_tag="VQ865_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001108652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-grasp domain-containing protein"
                     /protein_id="HET3135301.1"
                     /translation="MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLR
                     NSLTEYFRVDNLENIDEVKRAVAFLFYKHGPIDRIESHNEYWLELDATLREQFNVFGA
                     KPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGA
                     AATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYA
                     YTPLDLMIYKMDNSYYVLKDMDPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYITIE
                     YNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASDFETQYCLATSRRANAHYVY
                     SEEDLLAKYSQQFKVKKVMPAAFAELQGDYLYMLTTPSRQEMDQMIADFGQRQE"
     gene            35868..37361
                     /locus_tag="VQ865_000949"
     CDS             35868..37361
                     /locus_tag="VQ865_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3135302.1"
                     /translation="MITGELKNKIDQLWEILWTEGNANPLTNIEQLTYLLFMKDLDSV
                     ELGRESDAEFLGIPYEGVFPKDKPEYRWSTFKNIGDAQEVYRLMTQEIFPFIKNLKGD
                     TDDTAFSRYMREAIFQINKPATLQKAISILDVFPTRGLDVDFDNDKQSITDIGDIYEY
                     LLSKLSTAGKNGQFRTPRHIIDMMVELMQPTIKDIISDPAMGSAGFLVSASRYLKRKK
                     DEWETNTDNINHFHNQMFHGNDTDTTMLRLGAMNMMLHGVENPQISYLDSLSQDNEEA
                     DKYTLVLANPPFKGSLDYNSTSNDLLATVKTKKTELLFLSLFLRTLKPGGRAAVIVPD
                     GVLFGSSKAHKGIRQEIVENHKLDAVISMPSGVFKPYAGVSTAILIFTKTGNGGTDKV
                     WFYDMKADGLSLDDKRQPISDNDIPDIIERFHHLEKEAERQRTDQSFFVPVAEIKEND
                     YDLSINKYKEIEYEKVEYEPTEVILKKINDLEKEIQAGLAELEKLLK"
     gene            37374..>37881
                     /locus_tag="VQ865_000950"
     CDS             37374..>37881
                     /locus_tag="VQ865_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3135303.1"
                     /translation="MKKVKLGEVLSLKKGKKATVLAEQTTLSQRYIQIDDLRNNNNLK
                     FTESLNMTEALPDDILIAWDGANAGTVGYGLSGAVGSTITVLKKNERYKEKIISDYLG
                     VFLESKSQYLREHSTGATIPHLNKNILLDLQLELLGIEEQENIICILNTIKGLITKRK
                     LQLDELNLL"
BASE COUNT        11462 a         6889 c         8391 g        11139 t
ORIGIN      
        1 agcgaaatta tcgcctataa tctttcaact tcacccaact tagaacaagt acaaacaatg
       61 ttggaacagg cattcacaga gaagcactac gagaatacga ttctccatag tgaccaaggc
      121 tggcaatatc aacacgattc ttatcatcgg ttcttagaga gtaagggaat tcaagcatcc
      181 atgtcacgca agggaaacag ccaagacaat ggtatgatgg agtccttctt tgggattctg
      241 aaatcggaaa tgttttacgg ttatgagaag tcgtttcagt cgcttaagca attggaacaa
      301 gccattatag actatattga ttactacaac aacaagagaa ttaaggtaaa actaaaagga
      361 cttagccctg tgcaatacag aactaaatcc ttcggataaa ttaattgtct aacttttggg
      421 gggcagttca cagaactggc attttatttt ttaggatctt gatgggttag gttcaatccc
      481 caagggacca aattttcagt tttatttttg atacgagcta tattgtcctt atgacgaatg
      541 ataatcaaac tagcaagtgc taagataata gcgatgaaga gagagtcata gttactcagg
      601 ataaaaccaa aaagtggaaa gagcagaacc ccgataacag ccgcgatcga tgctgtgaca
      661 ctagacagtg aaatcatact gccaagatag agagctccaa agaagataat cgcaaggtag
      721 agacagaaga taggcgcaaa tccgaaaatt actccagcac tggttgcgac agccttacca
      781 cctttaaatc ctgcaaagat agggaaggta tggccgataa cagccaaaag tccaaagatg
      841 agaggagaaa cgccttgtag atgaaaaata atcggaagca gcgttgctag ggttcctttg
      901 aaaaagtcaa tcacaaaggt tgccatacca gctttcttac ctaaaatgcg gaaggtattg
      961 gtcgttccag tgttaccaga accatgctcg cgtagattga tttgaaagaa tacttgtcca
     1021 atccagagac cagatggaat cgaacccagc agataggcta ggattaataa aactattgta
     1081 atcatactcc tattatatca tgaattggga aagaaaagca gagaatctct gctaaaattg
     1141 tcacatcgga gaaagaaaaa ttttgcaaaa tccttggaaa acctgtagaa tagtaaagat
     1201 gaacgaatag gaggttcctt gtgtcaaaaa aggaaatcaa tattaacaat tataatgatg
     1261 atgctattca ggtgctagaa gggttggatg cggtccgaaa acgtccaggg atgtatattg
     1321 gatcgaccga tggcgctggt cttcatcacc tagtttggga aatcgttgat aatgcagtcg
     1381 atgaagcctt gtctgggttt ggtgatcgta tcgatgtaac catcaataaa gacggtagtc
     1441 taacggttca agaccatgga cgtgggatgc cgacaggtat gcacgctatg ggaattccaa
     1501 ctgttgaggt tatctttacc attcttcatg ccggagggaa attcggtcaa ggtggctata
     1561 agacatcagg tggacttcac ggagtgggtt cttccgttgt taacgccctt tctagctggt
     1621 tagaagttga aattacccgt gatggcgcag tttacaagca acgtttcgaa aatggtggaa
     1681 aacctgtcac gactttgaag aaaatcggta cagcacccaa gtctaaaaca ggcaccaaag
     1741 ttacttttat gcctgacgcg actatatttt ctacgacaga tttcaagtac aataccattt
     1801 cagagcgcct taatgaatca gcctttctct tgaaaaatgt gaccttgtct ttaacggaca
     1861 agcgaacaga tgaagcgatt gagttccact atgagaatgg agtacaagat tttgtttctt
     1921 atctcaacga agataaggaa atcttgacgc cagttcttta ctttgaaggg gaagacaatg
     1981 gttttcaagt ggaagtagcc ctccagtaca atgacggatt ctcagataac attctatcct
     2041 ttgtcaataa cgttcgcacc aaggacggtg gaacgcacga gacaggactc aagtctgcca
     2101 ttaccaaggt catgaatgac tatgcacgta aaacaggtct tctcaaggaa aaagataaaa
     2161 accttgaagg ttcagactat cgtgagggac tagcggccgt tctttctatc ttagttcctg
     2221 aagaacactt gcagtttgaa ggacagacca aggataaact aggaagcccc ctagctcgcc
     2281 cagttgtgga tggaatagtg gctgataagt tgaccttttt ccttatggaa aatggggaat
     2341 tagcttctaa cctcatccgc aaggctatca aggcccgtga tgctcgtgaa gcagcacgta
     2401 aggcgcgtga tgagagccga aatgggaaga aaaacaagaa agataagggc ttgttgtctg
     2461 ggaaattgac cccagcccaa tctaagaatc ctgctaagaa tgaactctat ctagttgagg
     2521 gggactctgc cggtggttct gccaaacaag gtcgtgaccg caagttccag gctattctac
     2581 ctcttcgtgg taaggttatc aatacagcca aggccaagat ggcggatatc ctcaaaaatg
     2641 aagagatcaa taccatgatt tataccattg gtgcgggtgt tggagcagac ttctctattg
     2701 aagatgccaa ctatgataag atcattatca tgaccgatgc ggataccgac ggtgcccata
     2761 tccagacctt gctcttgaca tttttctacc gttacatgcg tccgctagtc gaggcaggtc
     2821 atgtctatat tgccctccca cctctttaca agatgtccaa aggtaaagga aagaaagaag
     2881 aagtggccta cgcttggacg gacggagaac tagaagaact ccgtaaacag ttcggtaaag
     2941 gcgctaccct ccaacgatac aaaggacttg gtgagatgaa tgcggaccag ctctgggaaa
     3001 caaccatgaa cccagaaaca cgtaccctca tccgtgtcac aattgaagat ttagcgcgcg
     3061 ccgaacgccg cgtcaatgtt ctcatgggag ataaggtaga accacgccgt aaatggattg
     3121 aagataatgt caagtttacg ctagaagaag cgacagtgtt ttaatgaaag aaaataatat
     3181 gttagtaaac tggaaattag agtcggatgt gaatgactat gtgaaaaagc agtttgaaaa
     3241 tcttggtttg aaaaaattgc aggattatta atgaagaatc tgctatgagt gcttatctca
     3301 aagaggcgct taagggagcg gctaagacac aaactaagac taattttgga aaaccagatt
     3361 ttcatattga aaaatacaaa caggatagtt tggttactta tcgtaactga acacgggagg
     3421 aattcccgta aaatatcttt tactgcataa aaacctactc tacattcttt gaaaggagtt
     3481 gaacacgccc tagatactgt gtgaaaaaga taaattctct tgtgagtttg cttacttcaa
     3541 gaattttcta ttttcacttg gtattttatg ggctttgtat cttatgtcta acattcaaaa
     3601 catgtccctg gaggacatca tgggagagcg ctttggtcgc tactccaagt acattattca
     3661 agaccgggct ttgccagata ttcgtgatgg gttgaagccg gttcagcgcc gtattcttta
     3721 ttctatgaat aaggatagca atacttttga caagagctac cgtaagtcgg ccaagtcagt
     3781 cgggaacatc atggggaatt tccacccaca cggggattct tctatctatg atgccatggt
     3841 tcgtatgtca cagaactgga aaaatcgtga gattctagtt gaaatgcacg gtaataacgg
     3901 ttctatggac ggagatcctc ctgcggctat gcgttatact gaggcacgtt tgtctgaaat
     3961 tgcaggttac cttcttcagg atatcgagaa aaatacagtt ccttttgcat ggaactttga
     4021 cgatacggag aaagaaccaa cggtcttgcc agcagccttt ccaaacctct tggtcaatgg
     4081 ttcgactggg atttcggctg gttatgccac agacattcct ccccataatt tagctgaggt
     4141 catagatgct gcagtttaca tgattgacca cccaactgca aagattgata aactcatgga
     4201 attcttgcct ggaccagact tccctacagg ggctattatt cagggtcgtg atgaaatcaa
     4261 gaaagcttat gagactggga aagggcgcgt ggttgttcgt tccaagactg aaattgaaaa
     4321 gctaaaaggt ggtaaggaac aaatcgttat tactgagatt ccttatgaaa tcaataaggc
     4381 caatctagtc aagaaaatcg atgatgttcg tgttaataac aaggtagctg ggattgctga
     4441 ggttcgtgat gagtctgacc gtgatggtct tcgtatcgct atcgaactta agaaagacgc
     4501 taatactgag cttgttctca actacttatt taagtacacc gacctacaaa tcaactacaa
     4561 ctttaatatg gtggcgattg acaatttcac acctcgtcag gttgggattg ttccaatcct
     4621 gtctagctac atcgctcacc gtcgagaagt gattttggcg cgttcacgct ttgacaaaga
     4681 aaaggctgag aaacgtctcc atatcgtcga aggtttgatt cgtgtgattt cgattttgga
     4741 tgaagtcatt gctcttatcc gtgcttctga gaataaggcg gacgccaagg aaaacctcaa
     4801 agttagctat gattttacgg aagaacaggc tgaggctatc gtaactttgc aactgtaccg
     4861 tttgaccaat accgatgtgg ttgtcttgca ggaagaagaa gcagagcttc gtgagaagat
     4921 tgctatgctg gcggctatta tcggtgatga aaggactatg tacaatctca tgaagaaaga
     4981 acttcgtgag gtcaagaaga aatttgcaac tcctcgtttg agttctttag aagacactgc
     5041 gaaagcaatt gagattgata cagctagtct tatcgctgag gaagatacct acgtcagcgt
     5101 gaccaaggca ggttacatca agcgtaccag tccacgttcc tttgcggctt ccaccttgga
     5161 agaaattggc aagcgtgatg atgaccgttt gatttttgtt caatctgcca agacaaccca
     5221 gcacctcttg atgttcacaa gtcttggaaa tgtcatctac agaccaatcc atgagttggc
     5281 agatattcgt tggaaggaca tcggagagca tctgagccaa accatcacaa actttgaaac
     5341 gaatgaagaa atcctttatg tggaagtact ggatcagttt gacgatgcga caacctactt
     5401 tgcagtgact cgccttggtc aaatcaaacg ggtagagcga aaagaattca ctccatggcg
     5461 gacctataga tctaagtctg tcaagtatgc taagctcaaa gacgatacag atcagattgt
     5521 agcagtggct ccgattaaac tagatgatgt tgtcttggtt agtcaaaatg gttatgccct
     5581 gcgtttcaat atcgaagagg ttccggttgt cggtgctaag gcagcaggtg tcaaggctat
     5641 gaatttgaaa gaagatgatg tcctccaatc tggctttatc tgtaatactt cgtccttcta
     5701 cctcttgacc cagcgtggaa gcttgaaacg tgtttctatt gaggaaattc tagcaaccag
     5761 ccgtgccaaa cgaggattac aagtcttgcg tgagttgaaa aacaaaccgc atcgtgtctt
     5821 cttggcagga gcagttgcag agcaaggatt tgttggcgat ttcttcagta cggaagtgga
     5881 tgtgaacgac caaactctgc ttgtccaatc caataaagga acaatctatg aaagccgatt
     5941 gcaagacttg aacttgtcag aacgcactag caatggaagc ttcatttctg acacgatttc
     6001 agatgaagaa gtttttgacg cttatcttca ggaagtagtt actgaagata aataagtgaa
     6061 atgaagaatc agttctaaga gctggttttt attggagaaa ttttctgaaa attacaaaat
     6121 atacttgcta ttttagaaaa atagtgtaga atataagaaa taggttttta gaataaggag
     6181 tggaatatga cagtaacgat tgattgggaa aacctcggtt tttcctatat gaaattacct
     6241 tatcgctatc ttgctcattt caaaaatgga caatgggatc aaggagagct tacagaggat
     6301 gcaactttgc atatttcaga gtcttctcca agtcttcact atggacaaca agcatttgaa
     6361 ggtttgaaag cttatcgtac taaggatggc agtgttcaac tgttccgtcc tgatgaaaat
     6421 gctaaacgtc tgcaacgtac atgtgaccgt ctcttgatgc cacaagttcc gacagacatg
     6481 tttgtagaag cttgtaaagc agttgtccgt gcgaatgaag aatacgtacc accatacgga
     6541 acaggtggaa ccttatatct tcgccctctt ttgattggtg tcggagatat tatcggggta
     6601 aaaccggcag aagagtacat tttcaccatc tttgctatgc cagttggaaa ttactttaaa
     6661 ggtggtttgg tcccaaccaa cttcttgatt caggatgagt acgaccgtgc agcaccaaat
     6721 ggtacaggtg cggctaaggt tggtggaaac tatgctgcaa gtctcttacc aggaaaaatg
     6781 gccaagtcac gtcatttctc agatgttatc tatctggacc catcaactca tacaaagatt
     6841 gaagaagtcg gatcagctaa cttctttgga attacagctg ataatgaatt tgtaacacca
     6901 ttgagtccat ctatcttgcc atctattacc aagtattcct tgctttattt ggcagaacat
     6961 cgcttgggat taactcctat tgagggtgat gttccaattg ataatcttga ccgttttgta
     7021 gaggcaggtg cctgtggtac agcagcggtt atttctccaa ttggaggtat tcaacatggt
     7081 gatgatttcc atgtattcta tagtgaaaca gaagtaggtc ctgtgacgcg taaattatat
     7141 aatgaattga cgggtattca gtttggcgat attgaagcgc cagaaggttg gattgtaaaa
     7201 gtagattaaa ataaaccaaa ggagattttt tatgaaatag aaaaagtggc tcttaacagc
     7261 aggagtggtc ctgagcacgt cagctatttt agtggcttgt ggaaaaactg ataaagaagc
     7321 agatgcaccg acaacatttt cttatgtcta tgcagtagat ccagcatcat tgggctacag
     7381 tatagcgact cgaacatcga ggacagacgt tattggaaat gttattgatg gtttgatgga
     7441 aaatgataaa tacggcaatg ttgctccttc tcaaaaagac tatgatttga acggtacagg
     7501 atgggctcca agctatcaag atccagcgtc ttacttgaat attatggatc caaaatctgg
     7561 ttctgccatg aaacaccttg gcattacgaa aggaaaagat aaggatgttg tagctaaacc
     7621 tggtttggat aaatataaga aattgttaga agatgctgtt tctgagacca ctgacctaga
     7681 gaagagatat gaaaaatatg ccaaagctca agcttggtcg acagatagtt cattattgat
     7741 gccaacagct tcatctggtg gttttccagt tgtaagtaac gtagtaccat tctcaaaacc
     7801 atactcacaa gttggtatta agggggaacc atatatcttt aaaggaatga aattgcaaaa
     7861 agatattgtt acaacaaaag aatataacga ggtttttaaa aaatggcaaa aagaaaaatt
     7921 ggaatccaat agcaaatacc aaaaagaact agaaaaatac attaaataag gaatggtatt
     7981 gatcttgata aaatttttaa aatactgtca ttttgaatat aaaggagttt gatatggagt
     8041 ggattagatt aataggaata gcaatcattg ttgtgggttt tattttaaaa tttgatacaa
     8101 ttgcaacagt agtcttagct ggtttggtta cagctttagt ttcaggtgtt tctctcgttg
     8161 aatttttgga gattttggga aaagaattta gcaatcagcg agtgctcacg atttttatgg
     8221 ttaccttgcc tcttgtgggg ctgtcagaaa cctttggact caagcaacga tcaatcgatt
     8281 tgattcgaaa gattaaaggt ctgacagttg gaaacttcta tacagtttat ttctttattc
     8341 gagagttagc tggtttcttt tcaattcgtc taggaggaca ccctcagttt gtcagacctt
     8401 tggttcaacc tatgggagaa gcagctgcag agtctcaatt aggtagaaag ttaacagagg
     8461 ttgaagatga gacaataaaa gcgcgtgcgg ctgcgaatga aaattttgga aatttctttg
     8521 ctcaaaatac gtttgtaggt gctgggggag tcctcttgat agggggaaca ttagatcagt
     8581 taggctatga aagcaattat gcagggattg cttctacatc tattattgtt gctgttataa
     8641 cacttattgt agtggggatt tacaattatt tatttgataa aaaattgata tcaaaaaaga
     8701 ctaggggagg agaacaaaaa tgacagagtt ggcaaagcaa ctattagagt tgacctatat
     8761 tgtgattggt tgtcaatttc tccatacagc ctattgtagt tataaagata aaacaaaccc
     8821 agttcgactt gggacatctg cattttggac tctattgtct attacgttta taggtggttc
     8881 ctatatgcca aatatgagta ttggtattat tgtaatccta ttatcgctgt taacattgtt
     8941 taagcaagtc cgtatcggaa ccttgccatc cttagatgaa atgaaagcca atattgaatc
     9001 taacaggttg aaaaataaaa tttttattcc agttatgctg atggcaatac ttgcgttggt
     9061 cttagcgcaa atgattccag aatttagcaa gatttcgatt agccttgccg ccttgtttgc
     9121 tacaatttct gttcttgtga ttaccaatag tcaccctaag agtctgttat cagaaaataa
     9181 tcgaatgact cagcaagttt caacaagtgg tattgttcct caattattag gggctttggg
     9241 ggctattttt actgtagcag gtgttggtga tgttatctct catctgatta gcggtattgt
     9301 tccttcagat agtcgcttta taggagtttt ggcttatgtt cttggaatgg ttctattcac
     9361 aatgattatg ggaaatgctt ttgcagcatt caccgttatt acagcaggtg ttggagttcc
     9421 ctttgtattt gctctgggag ctaatccaat tgtggctggt gctcttgcca tgacagcagg
     9481 ttattgtggg accttattga ccccaatggc tgctaatttt aacgctctac cagcagcatt
     9541 gatggatatg aaagatcaga atggcgttat aaaggctcaa gcaggtgttg ctctagtaat
     9601 gattgttatt cacatattct taatgtactt tctcgcattt tagtaaagga aaataaaatg
     9661 aaaatattgg ttacaggttt taatcctttt ggaggtgaaa agattaatcc agctttggag
     9721 gctgtaaaat tattaccatc tgagattaat ggggctgaag ttcgctgggt agaaattcca
     9781 acggtttttt ataagtcgtc agaagtttta gaggcagaaa tattacgata tcaaccagat
     9841 gctgtacttt gtattggaca agcaggcggc aggaccggct taacacctga acgagtggct
     9901 attaatcaag atgatgctcg catacctgat aacgaaggca atcaaccaat tgatacaccg
     9961 attcgtattg atggagcatc ggcctatttt agtagtttac ctatcaaagc gatggtacaa
    10021 gctatcaaaa aacagggact tccggcagtt gtatccaata gtgcaggaac ctttgtttgc
    10081 aatcatttga tgtaccaagc tctttattta gtggataaaa aattccctaa tatgagagca
    10141 ggtttcatgc atattccata tatgatggaa caagtagtaa ataagccgaa tactgcagga
    10201 atgagtctat gtgatattgt aagaggcata gaggtagcta ttgaagctat tgtagactac
    10261 aaagataagg atttgcagtt agtaggcggt gagactcact gataacctaa aaaggatagt
    10321 caattatgct tgtttactaa ctattaacta tgctaaatca attgaggttg tttacataaa
    10381 actctatatc agagaagcct gatatagagt tttttcttgc tagttttagg attttcttgt
    10441 aaaatagaaa aagtgaagag aggtatgaaa tgagcaagaa agataaaaaa atcgaaattc
    10501 aagtagcgga tgccaaagtt aatgttggta aagacagttt tgaaggttat acattgacta
    10561 tcggtaaaaa agttatcgga gaaattgccg aattagacgg acaatttgcc attataaaga
    10621 atgggaatgt cgatagtttt tataaaaaat tggaaaaagc tgtggaaatt ttgattgaaa
    10681 attataattt agcaaaataa gtcttgtttt tttgaaattt tcatgatata atagtccatg
    10741 ttgattgtag gagagatagc gaagaggcta aacgcggcgg actgtaaatc cgctccttcg
    10801 ggttcggggg ttcgaatccc tctctctcca tttcattaat ggggtatagc caagcggtaa
    10861 ggcaagggac tttgactccc tcatgcgttg gttcgaatcc agctacccca gttcttaggt
    10921 aataatcaag ataaaaagca aaatatctta gggtatttta tttttataat tgaaagacgt
    10981 gaatgatatg aacatgtcct tgcgggtgct taggaaaaaa attataagta tgtcaagttt
    11041 aagaaaaact tgattgttgg aggatttttt agatgaacga atttgaagat ttgctaaata
    11101 gcgttagtca agttgagact ggtgatgttg ttagtgctga agtattgaca gttgatgcga
    11161 ctcaagctaa cgttgcaatc tctggaactg gtgttgaagg tgtcttgact cttcgcgaat
    11221 tgacaaacga tcgtgatgca gatatcaatg actttgttaa agtaggagaa gtattggatg
    11281 ttcttgtact tcgtcaagta gttggtaaag atactgatac agttacatac cttgtatcta
    11341 aaaaacgcct tgaagctcgc aaagcatggg acaaacttgt tggtcgcgaa gaagaagttg
    11401 ttactgttaa aggaacgcgt gccgttaaag gtggactttc agtagaattt gaaggtgttc
    11461 gtggatttat cccagcttca atgttggata ctcgtttcgt acgtaacgct gagcgttttg
    11521 taggtcaaga atttgatact aaaatcaaag aagttaacgc taaagaaaac cgcttcatcc
    11581 tttcacgtcg tgaagttgtt gaagcagcta ctgcagcagc tcgcgctgaa gtattcggta
    11641 aattggctgt tggtgatgtt gtaactggta aagttgctcg tatcacaagc ttcggcgctt
    11701 tcatcgacct tggtggtgtt gacggattgg ttcacttgac tgaattgtca catgaacgta
    11761 acgtatcacc aaaatcagtt gtaactgttg gtgaagaaat tgaagtgaaa atccttgatc
    11821 ttaacgaaga agaaggacgt gtatcacttt cacttaaagc aacagtacca ggaccatggg
    11881 atggcgttga gcaaaaattg gctaaaggtg atgtagtaga aggaacagtt aaacgtttga
    11941 ctgacttcgg tgcatttgtt gaagtattgc caggtatcga tggacttgtt cacgtatcac
    12001 aaatttcaca caagcggatt gaaaatccaa aagaagctct taaagttggt caagaagttc
    12061 aagttaaagt tcttgaagtt aacgcagatg cagaacgcgt gtcactttct attaaagctc
    12121 ttgaagaacg tccagcccaa gaagaaggac aaaaagaaga aaaacgtgct gctcgtccac
    12181 gtcgtccaag acgtcaagaa aagcgtgatt tcgaacttcc agaaacacaa acaggatttt
    12241 caatggctga tttgtttggt gatatcgaac tttaatcaaa ttgaaaattc acaaaatcct
    12301 ttgtttacta aacaagggat ttttcttttg tctctgctcc ttttttgata taatagttct
    12361 atgttaaaat cagaaaaaca atcacgttat caaatgttaa atgaagaatt gtccttccta
    12421 ttggaaggcg aaaccaatgt tttggctaat ctttccaacg ccagtgctct tataaaatca
    12481 cgttttccta ataccgtatt tgcaggcttt tatttgttcg atggaaagga attggtttta
    12541 ggtcccttcc aaggaggtgt ttcctgcatc cgtattgcac taggcaaggg tgtttgtggt
    12601 gaggcagctc actttcagga aactgttatt gttggagatg tgacgaccta tctcaactat
    12661 atttcttgtg atagtctagc taaaagtgaa attgtggtgc cgatgatgaa gaatggtcag
    12721 ttacttggag ttctggatct ggattcttca gagattgagg attacgatgc tatggatcga
    12781 gattatttgg aacaatttgt cgctattttg cttgaaaaga caacatggga ctttacgatg
    12841 tttgaggaaa aatcttaatg tatcaagcac tttatcgaaa atatagaagt caaaacttct
    12901 cccagttagt tggtcaagaa gttgtggcta agactcttaa acaagcggtg gagcaagaga
    12961 aaataagtca cgcttatctt ttttctggtc ctcgtggaac gggaaaaacc agtgttgcta
    13021 aaatctttgc caaggctatg aactgtccca atcaagtggg tggcgaacct tgcaataact
    13081 gctatatttg tcaagcagtg acggacggta gtttagaaga tgtcattgaa atggatgcag
    13141 cttctaataa tggggtagat gaaattcgcg aaattcgtga taaatctacc tatgcgccta
    13201 gccttgctcg ttataaggtt tatatcatag atgaggttca catgctgtct acaggggctt
    13261 ttaatgccct cctaaagacg ctggaagaac caacacagaa tgtagtcttt attttggcca
    13321 ctactgaatt gcacaagatt cctgctacta ttctatcccg tgtgcaacgt tttgagttta
    13381 aatcaattaa gacacaggat attaaggaac atattcacta tatcttagaa aaagaaaata
    13441 tcagttctga accagaggct gtggaaatca ttgccagacg ggcggaaggt ggaatgcggg
    13501 acgccttgtc tattttggat caagccctga gtttgacaca gggaaatgag ctgacgactg
    13561 ctatctctga agaaattact ggcaccatta gcctatcagc cttggatgat tatgtggcgg
    13621 ccttgtctca acaggatgtt cccaaagctt tgtcttgctt gaatcttctt tttgacaatg
    13681 gtaagagcat gactcgtttt gtgaccgatc ttttgcacta tttaagagac ttgttaattg
    13741 ttcaaacagg gggagaaaat actcatcata gttcagtctt tgtagaaaat ttggcacttc
    13801 ctcaaaaaaa tctgtttgaa atgattcgct tagcaacagt gaatttagca gatattaagt
    13861 ctagtttgca gcccaagatt tatgctgaaa tgatgaccgt ccgtttggcg gaaatcaagc
    13921 ccgaaccagc tctatcagga gcggttgaaa atgaaattgc tacgctgaga caggaagttg
    13981 cccgtctcaa acaagagctt tctaatgcag gtgcggttcc taaacaagtt gcaccagctc
    14041 ctagtcgacc agctacgggc aaaacagtct atcgtgtcga tcgcaataaa gtgcaatcta
    14101 tcttacaaga ggccgtcgaa aatcctgatt tagcacgtca aaatctaatt cgtttgcaga
    14161 atgcctgggg agaggtaatt gaaagtctag gtgggccgga caaggctctg ctagttggtt
    14221 ctcaaccggt tgctgccaat gaacaccatg ctattcttgc ttttgagtct aacttcaatg
    14281 ctggtcaaac tatgaaacga gacaatctca ataccatgtt tggtaatatc ctcagtcagg
    14341 cggcaggttt ttcacctgag attttagcta tttccatgga ggaatggaaa gaagttcgcg
    14401 cagccttttc agccaaagcc aaatcttctc aaactgaaaa agaagtagaa gaaagcctga
    14461 ttccagaagg atttgaattt ttggctgata aagtgaaggt agaggaagac taaagaaaga
    14521 tttcatgata caataagttt atgaataaac aacaatttat tattatggcg ctatttacag
    14581 ctgctgagac ctattttttc aatgaagcct ggatgactgg ccgctatatt atggcagcct
    14641 tttgggcaat tttactcttt agaaatttcc gagtcagtta tgtgatgggt aaaattgttg
    14701 atgtcatcga tcagcatttt aataggaaag actagccctc agcttccaga caaaatcaaa
    14761 gccttttagg cttttttttg ttatactaga aaagtatatt tatagaattt ttgctctatt
    14821 tctggggaaa tcagacgttt ttctagtaag tactgtaaaa gttttgaaaa agaaaggaac
    14881 tatcatgtca gtaatagaga tcaaagatct tcacgttgag attgaaggaa aagaaatttt
    14941 aaaaggggtt aacctgaccc tgaaaacagg agaaattgcc gctatcatgg gaccaaatgg
    15001 tacaggtaaa tcgactcttt ctgccgctat catgggaaat ccaaactatg aagtaactaa
    15061 aggtgaagtt ttgtttgatg gcgtaaacat ccttgagttg gaagtggatg agcgtgcgcg
    15121 tatgggactt ttccttgcta tgcaataccc atcagaaatc cctggaatta ccaatgctga
    15181 gtttcttcgt gccgctatga atgcgggtaa agaagatgat gagaagattt cagttcgtga
    15241 gtttattact aagctagatg aaaaaatgga attgctcaac atgaaagaag aaatggcaga
    15301 gcgttacctc aacgaaggct tctctggtgg tgagaaaaaa cgcaatgaaa ttcttcaact
    15361 tttgatgttg gagccaacat ttgctctttt ggacgagatt gactcaggtc ttgatattga
    15421 cgctcttaaa gttgtgtcta aaggtgtcaa tgccatgcgt ggtgaaggtt ttggtgctat
    15481 gatcatcact cactaccaac gtcttttgaa ctatatcaca cctgatgtgg tacacgtgat
    15541 gatggaaggt cgtgttgtcc tttctggtgg tccagaattg gctgcgcgtt tggaacgtga
    15601 aggatacgca aaattagctg aagaacttgg ctacgactac aaggaagaat tgtaatttcc
    15661 tcgtatcttt taggagaagt aaatgactag agaaaatatt aaactttttt cagaaatgca
    15721 cgctgaacca agctggttgg ctgatctccg tcaaaaagct tttgacaaga ttgagacttt
    15781 ggaattacca gttattgagc gtgtcaaatt ccaccgttgg aatctgggtg atggaacgat
    15841 tacagaaaat gagccatcag caaatgttcc agatttcaca gctttagatc atcacttgaa
    15901 gttggtgcaa gtaggaactc aaactgtttt cgaacaaact ccagttgagt tagctgaaca
    15961 gggtgttgtc ttcacagact ttcactcagc tttagaagaa attccagagc tgatcgaaga
    16021 attcttcatg tcatctgtta agtatgatga tgacaagttg gcggcttacc acacagctta
    16081 ctttaacagt ggtgctgtac tctatattcc agataacgta gaaatcacag agccaattga
    16141 aggaattttc taccaagata gcgatagcaa tgtgccgttt aacaagcata ttatgattat
    16201 cgctggtaaa aattctaaga ttagttatct ggagcgttta gagtcacgcg gtgaaggaag
    16261 tgacaaagca actgccaata tcacagtgga agtgattgca cattctggtg cgcaagtcaa
    16321 gtttgctgct atcgaccgtc taggtgaaaa cgtcactgcc tacattagcc gtcgtggtaa
    16381 attaggcaac gatgcaagta ttgactgggc tatcggtgtc atgaacgaag gaaatgtcgt
    16441 tgctgatttt gatagtgact tgattggtaa tggtagctat gctgacctca aggttgtagc
    16501 tctttcaagt ggtcgtcagg tacaagggat tgatactcgt gtaactaact atggctgcaa
    16561 ctctatcgga aatatcctac aacatggggt tatccttgaa aaagcaactt tgactttcaa
    16621 tggtatcggc cacatcatca agggtgctaa gggagcagat gcccaacaag agagccgtgt
    16681 tctcatgctt tcagaccaag cgcgttcaga tgctaaccca attcttttga ttgatgaaaa
    16741 tgatgtcact gcaggacacg cagcgtctat cggacaagtt gatccagaag acatgtatta
    16801 cctcatgagt cgtggattgg ataaggcaac tgcagagcgt ttggttgttc gtggtttcct
    16861 tggatctgtt atcgtggaga ttccagtcaa ggaagttcgt gatgaaatga ttgcaactat
    16921 cgaagagaaa ttgtcaaaac gctaagggga agcctatgtt agatgtagaa gcgattcgca
    16981 aggattttcc aattttagat cagattgtca atgatgaacc tctggtctat ctggacaatg
    17041 ctgcgacgac acaaaaacca ctagtagttc tgaaagctat taacagttac tatgagcagg
    17101 acaatgccaa tgttcaccgt ggtgtccata ccttagcgga acgagcgaca gcttcttatg
    17161 aagctgctcg tgaaaccatt cgtaagttta ttaatgcagg ctctacaaag gaagttctct
    17221 ttaccagagg aacgacaacc agccttaact gggtggcacg ctttgctgag gaaattctca
    17281 ctgagggaga ccaggtcttg atttcagtaa tggaacacca ttctaatatc attccatggc
    17341 aggaagcttg tcgaaagact ggagcagagc ttgtctatgt ctatcttaaa gacggtgcct
    17401 tggatatgga ggatttgcga gctaaattga ctgataaggt taaatttgtt tccctagctc
    17461 atgcctccaa tgttcttggt gtggtcaatc cgatcaagga aatcactcaa ttagcccacc
    17521 aagttggggc aatcatggta gtggatggtg ctcaatctac acctcatatg aagattgatg
    17581 tccaggactt ggatctggac tttttcgcct tttcgggtca caagatggct ggtccgactg
    17641 gtatcggtgt cctttacggc aaagaaaagt atcttgagca aatgtctcca gtagaatttg
    17701 gcggcgagat gattgatttt gtctacgagc aatccgctag ttggaaggaa ttgccttgga
    17761 aatttgaggc tggaacgcca aatatggcag gagctattgg acttgcgact gcagttgatt
    17821 atctggaaaa gattggtatg gatgccgttg aagctcatga acaggaattg attgcgtacg
    17881 tctatccaaa actgcaggca attgagggat tgaccattta cggttctcag gatttggctc
    17941 aacgttcggg tgttattgcc tttaacctag gtgatctcca tcctcacgat cttgcgacgg
    18001 ctctggatta tgaaggagtg gctgttcgtg ctggtcacca ttgtgcgcaa cccttgcttc
    18061 agtatttgga agtctcagca acagctcgtg caagttttta tatctataat accaaggcag
    18121 attgcgacaa actagtcgat gccctacaaa agacaaagga gtttttcaat ggcactttct
    18181 aaactagata gcctttatat ggcagtggta gcagaccatt cgaaaaatcc acatcaccaa
    18241 gggaagttag aagacgctga gcaaatcagt ctcaacaatc cgacttgtgg agatgtcatc
    18301 aatctctctg tcaagtttga tgcagaggac cgtttggaag atattgcttt tctaaattca
    18361 ggatgcacga tttcaactgc ttctgctagt atgatgacag atgccgtttt aggaaaaacc
    18421 aaacaagaaa ttttagaact ggcgactatt ttttctgaaa tggttcaagg gcaaaaagat
    18481 gagcgtcaag accaacttgg agacgcggca ttcttgtcag gtgttgccaa attccctcaa
    18541 agaatcaagt gtgcaaccct agcttggaat gcccttaaga aaacaattga aaatcaagaa
    18601 aaacagtaag acaagtttct tttgtcttat gaattattag aaatgaagaa agaaaggata
    18661 ttatggctga agaaagagta gaaccaaaac caattgacct tggtgaatat aaatttggtt
    18721 tccatgacga tgtagagcct gtcttatcga caggaaaagg actcaacgaa ggtgttattc
    18781 gtgaattatc tgctgctaag ggtgagcctg agtggatgtt ggagttccgt ttgaagtctt
    18841 atgaaacctt caaaaaaatg cccatgcaaa cttggggagc agacttgtca gagattgact
    18901 ttgatgactt aatctactac caaaaaccat ctgacaaacc agcccgttct tgggatgatg
    18961 tacctgaaaa gattaaagaa acctttgaac gtatcgggat tccagaagct gaacgtgctt
    19021 atttagcagg ggcttctgcc cagtacgagt cagaagtggt ttaccacaac atgaaggaag
    19081 agttccaaaa attaggtatt atctttacag atacagattc cgcactcaag gaatacccag
    19141 acttatttaa tcaatacttt gcgaagttgg taccgccgac agataacaag ttggcagccc
    19201 tcaactcagc agtatggtcg ggtggaactt ttatctacgt gccaaaaggt gtcaaggtag
    19261 atattccact tcaaacttat ttccgtatca ataacgaaaa tataggtcag ttcgaacgta
    19321 ccttgattat cgttgatgag ggagcaagcg tccactacgt agaaggatgt acagcaccaa
    19381 catattcaag caatagctta cacgctgcca ttgtagaaat ttttgctttg gacggagctt
    19441 atatgcgtta tacaactatc caaaactggt ctgataacgt ctataacttg gtaacaaagc
    19501 gtgctaaggc tcaaaaggat gccactgttg agtggattga tggaaacttg ggtgccaaaa
    19561 cgactatgaa atatccatct gtttaccttg atggagaagg agcgcgtggt accatgctct
    19621 ctatcgcctt tgctaatgca gggcaacacc aagacacggg tgctaagatg attcacaatg
    19681 ctccacatac cagctcgtct attgtgtcta aatccatcgc taaaggtgga ggaaaggttg
    19741 actaccgtgg acaagtcacc tttaacaaga actctaagaa atctgtttcc cacattgaat
    19801 gtgataccat tatcatggat gacttgtcag catcagatac tattccattt aatgaaattc
    19861 acaactcgca agtggctttg gaacacgaag ccaaagtatc taagatttca gaagagcaat
    19921 tgtattatct catgagccgt ggattgtcag aatctgaggc aactgaaatg attgtcatgg
    19981 gatttgtaga accctttaca aaagaacttc caatggaata cgcagttgag ctgaaccgct
    20041 tgattagcta tgaaatggag ggatcagttg gataaaattt gattttatac tcttcgaaaa
    20101 tctcttcaaa ccacgtcagc atcgccttat cgtatgtatg gttactgact tcgtcagttt
    20161 catctacaac ctcaaaacag tgttttgagc aacctgcggc tagcttccta gtttgttctt
    20221 tgattttgaa gatgaacttg tatcaaaaaa tcgcggttta aaatcgcgat tttttataat
    20281 ttctcgttaa caaagcggac aaactgattc caccaaactt ttaagaagaa ggctttttca
    20341 attttcttgt ctgctaccat ttcgaaacta gggcgctctg tggtgatgta accttgacca
    20401 atcaagtcct tgtcttcata agtcaaatgg ccaaccactg ttccagcttc aagtggtgct
    20461 gggattgctt tggaatcagg tgtgaattga acagattgag aagattgatt cccaacacgt
    20521 tcgattagat agatatcctc tggagccact gcagttactg tatcttcttt tccatcttgt
    20581 acaggggctt tgctatcttg ataggcatcg ccttgttgaa cgattttgcg aagtgtaaat
    20641 gtagaagaaa tataatccat tagggaagat gtagctgtaa atcgagcgta aggattattg
    20701 tcttgatgat ctgcatttaa aacaactgtg atgactctca tgcctttttc gacagtagta
    20761 ccaacaaaag actctccagc cttatctgtt gttcctgttt ttagcccatc aaaaccacca
    20821 cggtaagcag gcataccttc taacatgtag ttggttgaag tgattgtcat cccagcaaaa
    20881 gtagaagaag gttttttggt gatttctaag acttgtgggt attttttgat gaggttgcga
    20941 gcaacgatag cgacatcata agcactaagc ttattttcct catctttttt agaacctggg
    21001 taaatgttat cccctagagt ttcattgtta agacctgtcg tattgacaac agtggcatcc
    21061 tgaattcccc attccaagag ttttgcccgc atcatatcga cgaaatcttt ttctgagcca
    21121 gcaattttct cagctagggc aatagcggcg ctgttggcac tagataccag agttgcttca
    21181 agcaactctt cgacagtata attacgggcc tccataggaa tattactggc ttcagaattt
    21241 gtcgtcaatt gataaggata atcagaaata tctacaggag tggagagggt aatacttccg
    21301 ttttccaaag cttcatagac tagataaaca gtaatcaatt ttgttatgga agcaatttcg
    21361 acaggttgcg ttgcatcctt ctcatagaga attttaccag tatttgcctc aacagcaatc
    21421 gcatgtttag cggcaatggt aaaatcttga gcaacagcag tagaaacacc ccctaaaaga
    21481 gagacagtta acaaagttaa aaatattttt ttcatagtag tcttattcta tcataaagaa
    21541 aaaaaatatt cttgctttaa taattcatct gttaagcttt ttgaaaatat ggtaaaataa
    21601 agtgagggag gtaactcatg tttcgtagaa ataaattatt tttttggacc acagaaattt
    21661 tactcttaac catcatcttt tacctatgga gacagatggg atctttgatt aacccttttg
    21721 ttagcgtgct taatacaatt atgattccat ttttattagg gggctttctt tattatttga
    21781 caaaccctat tgttactttc ttaaataaag tctgtaaact caatcgtttg cttggtattt
    21841 taattacctt gtgtactttg gtctggggaa tggtcatagg tgttgtctat ctcttaccta
    21901 ttttgattaa tcagttatct agtttgatta tatctagtca aactatttat agtcgagtac
    21961 aagacttaat catagactta tctaattatc ctgcgctcca gaatttggat gtagaagcta
    22021 caattcagca gttaaactta tcctatgttg atattcttca aaatatccta aatagcgtat
    22081 caaatagtgt ggggagcgtc ttgtcagctc ttatcagtac tgttttgatt ttgattatga
    22141 ctccagtttt tttggtttat ttcttattag atggacataa attcttgccc atgcttgaaa
    22201 gaacgattct aaagagggat cgcttgcata ttgcaggctt attaaagaat ttaaatgcga
    22261 cgattgctcg ctatattagt ggagtttcga ttgacgcaat cattataggt tgtttggctt
    22321 atattggcta tagtattatt ggtttaaaat atgctttagt ttttgccatt ttttctggtg
    22381 tagccaattt aattccttat gtggggccaa gtattggttt gattcctatg atcatcgcaa
    22441 atatattcac tgatccccat agactgctga ttgcagtgat ttatatgctt gttgttcagc
    22501 aggtagatgg caatatctta tatcctcgaa ttgtaggaag tgttatgaag gttcatccaa
    22561 tcacgatttt agttttactt ttgttgtcaa gcaatatcta tggtgtagtt ggaatgattg
    22621 tcgcagtgcc aacctattct atcttgaaag aaatttctaa gttcttatcc cgtttgtatg
    22681 aaaatcataa aataatgaaa gaacgagaaa gagaattagc taagtaaaag tcaggagaac
    22741 cctgattttt ctttactgga agtggccttt agattagaag actgaaaata agttaaagtc
    22801 ttaaactaat tttcacagct aagaatagta gaagttaatc tgataaaaat cgaaaaaacc
    22861 agtggaattc cgtgtcaggg taagttccac tggttttcat agtctattaa agttcgaatg
    22921 aaacctattt atagtatatt gaaactagaa tagtacacct ctaattctaa aacattgtta
    22981 gaaatcgatt tgactgtcct gatctattcg tcctattctt atttcatttt actatatttt
    23041 ggtgcaataa gtgaaaagta gtccgaataa tataaggatt gattttatag tttttaaact
    23101 caaatgaatt aaaataaaga gagtacgaaa attctcatct gaaagtattt tagaataatt
    23161 ctcttcgtga atttcttcaa aacagatagc ttcatcttag gtatgtgtta attggatttc
    23221 gtaagctcta tttacaatcg taaagttatg cactgaaaaa gttgtagtta gtcttccagt
    23281 ttgctaaatt tctcgaatag tatctttttt aggtatgtga tttctttttg catttttgag
    23341 ttagataagg tataatggtt ttattgtctt ttggggtcgt tacggattcg acaggcatta
    23401 tgaggcatat tttgcgactc gtgtggcgac gtaaacgctc agttaaatat aactgcaaaa
    23461 aataacactt cttacgctct agctgcctaa aaaccagcag gcgtgacccg atttggattg
    23521 ctcgtgttca atgacaggtc ttattattag cgagatacga ttaagccttg tctagcggct
    23581 tgataagaga ttgatagact cgcagtttct agacttgagt tatgtgtcga ggggctgtta
    23641 aaataataca taacctatgg ttgtagacaa atatgttggc aggtgtttgg acgtgggttc
    23701 gactcccacc ggctccatta ttcctttgca ttcttttgca ttccttggta aaacgttgtt
    23761 aaatcaacgt tttttatttt tatctttggt attcctttgc attcttttgc taaaaaggga
    23821 gtcacaaaca gaccctattt taaaaaaagg atagaaaaaa ggatacaaca tttgtcgcat
    23881 cctaaaaata atcttttttc gacggaagac atgggattcg aacccacgca cgctattaca
    23941 cgcctaccgc gtttccaaca cggcctctta agcctcttga gtaatcttcc aatacttact
    24001 caaatagtct accataaagg ctcttatctt gcaataaaaa ttctagaaat aagaaaaatg
    24061 atagattttg aaagaaaatg ataaaaaatg cttgacttca aaagaaagta tgatagaatg
    24121 aatagtgtaa acgataacag gaggtgattc ggtgttaaaa acagagcgga agcaactgat
    24181 tttagaggag ttaaatcaac atcatgtagt ttctctagaa aaattagtta gtttgctaga
    24241 aacgtcagaa tcaacggttc gaagagactt ggatgagttg gaagcggaaa acaagcttcg
    24301 tcgtgtgcat ggtggagcag aactccccca ctccttacag gaagaagaaa ccattcaaga
    24361 aaaatcggtc aaaaaccttc aagaaaagaa gttgctggct cagaaagcag cctctctcat
    24421 taaagaaaaa gatgtcatct ttatcgatgc tggaacaaca actgcttttt tgattcatga
    24481 attggtcaat aagaatgtta cagttgtgac caactccatt caccatgccg ctcagttggt
    24541 tgaaaagcag attccaactg tcatggttgg aggaaacgtc aagacggcga cagatgctag
    24601 tatcgggggc gttgctctta accagattaa ccaattgcac tttgaccgtg cctttatcgg
    24661 aatgaatggt gttgacgatg gctattatac gactcctgat atggaggagg gagctgtgaa
    24721 aagagctatt ttggagaatg ccaagcagac ctacgtcttg gtggattcgt caaaaattgg
    24781 acaaacttgc tttgccaagg tagcaccact caaacgcgct atcgttatca ctagtcaagg
    24841 gcatgagctc ttgcaggtta ttaaggagaa aacggaggta atagaagtat gatttataca
    24901 gtcacactca atccatccat tgactatatc gttcgtttgg accaagtcaa agttggtagt
    24961 gtaaatcgta tggacagtga tgataagttt gctggtggga aaggaatcaa tgtcagccgt
    25021 gtcttgaaac gtttgaatat accaaataca gcgacgggat ttatcggtgg ctttactggt
    25081 aaatttatca cagatacttt agcagaggaa gaaatcgaga cacgttttgt ccaggtggca
    25141 gaagatactc gtatcaatgt taaaatcaaa gcagaccaag aaacagaaat caacggaacg
    25201 ggtccaactg ttgaaccggt tcagctagaa gaattgaaag ctattttatc tagtctgaca
    25261 gcagaagata cagttgtctt tgcaggttca agtgctaaaa atctaggcaa tgttatctat
    25321 aaggatttga tttccttgac gcgccagact ggtgcgcaag tggtctgtga ctttgaagga
    25381 cagaccttaa ttgatagttt ggactaccag cctcttcttg taaaaccaaa caatcatgaa
    25441 cttggagcga tttttggggt taaactcgaa agtttagatg aaattgagaa atacgctcgt
    25501 gagttactgg ctaagggtgc tcaaaatgtt attatctcta tggctggtga tggcgccctt
    25561 cttgtcacat ctgagggagc ttacttcgct aaaccaatca aaggaacagt caaaaattca
    25621 gttggagctg gtgattctat ggttgctgga ttcacaggtg aatttgtcaa atcaaaagac
    25681 gcagtagaag ccttcaaatg gggagtggct tgcggaacgg caactacctt ctcagatgac
    25741 ttggcaacgg cggaatttat taaagaaaca tatggaaaag ttgaggtaga aaaaagatga
    25801 aaattcaaga cctattgaga aaagatgtca tgttgctaga tttgcaggca actgaaaaaa
    25861 cagctgtcat cgacgagatg attaaaaatt tgacagagca cggttatgta acagattttg
    25921 aaacatttaa agaaggaatt ttggcgcgtg aagctttgac ttctactggt ttgggtgatg
    25981 gaatcgcaat gcctcacagc aaaaacgctg ctgtcaaaga agcgacagtt ctatttgcta
    26041 agtcaaataa gggtgttgac tacgagagct tggatggaca agcaactgac ctcttcttca
    26101 tgattgcagc tccagaaggt gccaatgata ctcacttggc agccttggca gaattgtctc
    26161 aatacttgat gaaagacggt tttgcagaca aacttcgtca agcaacatct gcagaccaag
    26221 ttatcgaact ttttgaccaa gcttcagaaa aaactgagga acttgttcaa gcacctgcta
    26281 atgactctgg tgactttatc gtagctgtta cagcttgtac aacaggtatt gcccacactt
    26341 acatggccca agaagccctt caaaaagtag ctgctgaaat gggggttggt atcaaggtcg
    26401 aaaccaacgg tgctagcggt gttggaaatc aactaactgc agaagatatc cgtaaggcta
    26461 aagctattat cattgcagca gacaaggccg ttgaaatgga tcgatttgat ggaaaaccat
    26521 tgatcaatcg tccagttgct gacggtatcc gtaagacaga agagctaatt aacttggctc
    26581 tttcaggaga tactgaagtc taccgtgccg ctaatggtgc caaagctgca acagcctcta
    26641 acgaaaaaca aagccttggt ggtgccttgt acaaacactt gatgagtggt gtatctcaaa
    26701 tgttaccatt cgttatcggt ggtggtatca tgattgccct tgccttcttg attgacggtg
    26761 ctttgggtgt tccaaatgaa aaccttggca atcttggttc ttaccatgag ttagcttcta
    26821 tgttcatgaa aattggtgga gctgcctttg gtttgatgct tccagtcttt gcgggttatg
    26881 ttgcctactc tattgctgaa aaaccgggtt tggtagcagg tttcgtggct ggtgctattg
    26941 ccaaagaagg ttttgccttt ggtaaaattc cttatgccgc aggtggtgaa gcaacttcaa
    27001 ctcttgcagg tgtctcatct ggtttcctag gtgcccttgt tggtggattt atcgcaggtg
    27061 ccttggttct tgccatcaag aaatacgtta aagttcctcg ttcactcgaa ggtgctaaat
    27121 caatccttct attgccactt cttggaacaa tcttgacagg atttgttatg ctagctgtga
    27181 atatcccaat ggctgcaatc aacactgcta tgaatgactt cctaggcggt cttggaggag
    27241 gttcagctgt ccttcttggt atcgtccttg gtggaatgat ggctgttgac atgggtggac
    27301 cagttaataa agcagcttat gtctttggta caggtacgct tgcagcaact gtttcttcag
    27361 gtggttctgt agccatggca gcagttatgg ctggaggaat ggtgccacca cttgcaatct
    27421 ttgtcgcaac tcttcttttc aaagataaat ttactaagga agaacgtaac tctggtttga
    27481 caaacatcat catgggcttg tcatttatca ctgagggagc gattccattt ggtgccgctg
    27541 acccagctcg tgcgattcca agcttcatcc ttggttcagc agtagcaggt ggactcgttg
    27601 gtcttactgg tatcaaactc atggcgccac acggaggaat cttcgttatc gcccttactt
    27661 caaatgctct cctttacctc gtttctgtct tggtaggagc aatcgtaagt ggtgtggttt
    27721 atggttacct acgcaaacca caagcataaa aaatagaaaa atgaaaagat tggaccgttt
    27781 ggtgcagtct ttttctcttc ccgaaatgcc tgtgaaatat ggtataatag aagaatggca
    27841 aacaagaata caagtacaac aagacggaga ccgtctaaag cagaactgga aagaaaagaa
    27901 gcgattcaac gaatgttgat ttcgttagga attgcgattt tattgatttt cgcagccttc
    27961 aaattagggg ctgcaggtat aaccctttat aatttaattc gcttgctagt gggtagccta
    28021 gcttatctgg cgatattcgg cctattaatc tatctcttct ttttcaagtg gatacgaaaa
    28081 caggaaggac tcttatctgg ctttttcacc atatttgctg gcttactctt gatttttgag
    28141 gcctacttgg tttggaaata tggtttggac aagtccgttc taaaagggac catggctcag
    28201 gttgtgacag atctgactgg ttttcgaacg actagctttg ctggaggggg cttgatcggg
    28261 gtcgctcttt atattccaac agcctttctc ttttcaaata tcggaactta ctttattggt
    28321 tctatcttga ttttagtggg ttctctccta gtcagccctt ggtctgttta cgatattgct
    28381 gaatttttca gtagaggctt tgccaaatgg tgggaagggc acgagcgtcg aaaagaggaa
    28441 cgctttgtca aacaagaaga aaaagctcgc caaaaggctg agaaagaggc tagattagaa
    28501 caagaagaga ctgaaaaagc cttactcgat ttgcctcctg ttgatatgga aacgggtgaa
    28561 attctgacag aggaagctgt tcaaaatctt ccacctattc cagaagaaaa gtgggtggaa
    28621 ccagaaatca tcctgcctca agctgaactt aaattccctg aacaggaaga tgactcagat
    28681 gacgaagatg ttcaggtcga tttttcagcc aaagaagccc ttgaatacaa acttccaagc
    28741 ttacaactct ttgcaccaga taaaccaaaa gatcagtcta aagagaagaa aattgtcaga
    28801 gaaaatatca aaatcttaga agcaaccttt gctagctttg gtattaaggt aacagttgaa
    28861 cgggccgaaa ttgggccatc agtgaccaag tatgaagtca agccggctgt tggtgtaagg
    28921 gtcaaccgca tttccaatct atcagatgac ctcgctctag ccttggctgc caaagatgtc
    28981 cggattgaag caccaatccc tgggaaatcc ctaatcggaa ttgaagtgcc caactccgat
    29041 attgccactg tatctttccg agaactatgg gaacaatcgc aaacgaaagc agaaaatttc
    29101 ttggaaattc ctttagggaa ggctgttaat ggaaccgcaa gagcttttga cctttctaaa
    29161 atgccccact tgctagttgc aggttcaacg ggttcaggga agtcagtagc agttaacggc
    29221 attattgcta gcattctcat gaaggcgaga ccagatcaag ttaaatttat gatggtcgat
    29281 cccaagatgg ttgagttatc tgtttacaat gatattcccc acctcttgat tccagtcgtg
    29341 accaatccac gcaaagccag caaggctctg caaaaggttg tggatgaaat ggaaaaccgt
    29401 tatgaactct ttgccaaggt gggagttcgg aatattgcag gttttaatgc caaggtagaa
    29461 gagttcaatt cccagtctga gtacaagcaa attccgctac cattcattgt cgtgattgtg
    29521 gatgagttgg ctgacctcat gatggtggcc agcaaggaag tggaagatgc tatcatccgt
    29581 cttgggcaga aggcgcgtgc tgcaggtatc cacatgattc ttgcaactca gcgtccatct
    29641 gttgatgtca tctctggttt gattaaggcc aatgttccat ctcgtgtagc atttgcggtt
    29701 tcatcaggaa cagactcccg tacgattttg gatgaaaatg gagcagaaaa acttcttggt
    29761 cgaggagaca tgctctttaa accgattgat gaaaatcatc cagttcgtct ccaaggctcc
    29821 tttatctcgg atgacgatgt tgagcgcatt gtgaacttca tcaagactca ggcagatgca
    29881 gactacgatg agagttttga tccaggtgag gtttctgaaa atgaaggaga attttcggat
    29941 ggagatgctg gtggtgatcc gctttttgaa gaagctaagt ctttggttat cgaaacacag
    30001 aaagccagtg cgtctatgat tcagcgtcgt ttatcagttg gatttaaccg tgcgacccgt
    30061 ctcatggaag aactggagat agcaggtgtc atcggtccag ctgaaggtac caaacctcga
    30121 aaagtgttac aacaataaaa aaatagcttc tttccaagtt tggagggaag ctatttttct
    30181 ggctattgat tacttttata ctcttcgcaa atctcttcaa accacgtcag cttcgccttg
    30241 ccgtactcaa gtactgtcta cggctagctt cctagtttgc tctttgattt tcattgagta
    30301 ttattttctg aagttggagt attgggctgt ttttcatttt cagtggcagg tttacttgta
    30361 gcaggtgtag tagagtcctg agttgctgtt ttctgatctt cttttttctc ttccttgacg
    30421 ctagattttg gcgtttcttc ttgttgtgtt ttttcttgag aagtgttatt ttccttattt
    30481 ggagtagtat tttcctgagg ggattctttt tgaatttctt tgacaaaggt tgtcgtctgg
    30541 cttgtcgtag gttctttttt agtattttta ttattattat ccaaggcgtt catgatcgtg
    30601 atacccgcgg taatcaaacc aaggatacta ccgatagtag taatggtttt ttgaaaaaca
    30661 gtaaagcctt ttttgatatg ttctgttttc ggttttgaag ttctacgata gttagacata
    30721 cattctctcc tttgattatg atttattata ctctgtttct ttaaaaaaat cttaaaaaaa
    30781 gagaaattgc cctttcttgt cgcaggctcc gtttcatgat acaatagaag gagtgatttt
    30841 agaaagcgtg agaaacatga tttactttga taattcggcg acgaccaggc cctatccaga
    30901 agcccttgaa acctatatgc aggtggcttc aaaaatttta ggaaatccat ctagtctcca
    30961 tcgtttggga gaccaggcaa cacgaatttt agatgcttcc cgtcaacaga ttgcagattt
    31021 aatcggtaag aaaagtgatg aaatcttctt tacatctggt gggacagaag gggataactg
    31081 gatcatcaag ggagtagcat ttgaaaaagc ccagtttggc aagcacatca tcgtatcagc
    31141 cattgaacat ccagcagtta aggaatcagc cctctggttg aaagctcaag gttttgaagt
    31201 ggattttgct ccagttgata acaaaggatt tgtggatgtt gaggcgctag aagatttgat
    31261 aagacctgat acgaccctcg tttccatcat ggctgtgaac aatgaaatcg gctctatcca
    31321 acctattgag gctatttcag aattcttggc agacaagcca actatttcct tccacgttga
    31381 tgcggttcag gcgcttgcca agattccgac tgaaaagtat ctgacagaac gagtggattt
    31441 cgcgactttc tctggtcaca agttccacgg aatccgtggt gttggtttta tctatatcaa
    31501 gtctggcaag aagattacgc ctcttttaac aggtggtggt caggaacgtg attaccgttc
    31561 gacaactgaa aatgtggcag gaattgcagc gaccgctaag gctctccgtt tatctatgga
    31621 aaagctagat atctttagga gcaagactgg gcagatgaag gcagtgattc gtcaagcact
    31681 tctggactat ccggatatat ttgtcttttc agatgaggaa gacttcgccc ctcatattct
    31741 gacttttgga atcaagggtg ttcgtggtga ggtcattgtt cacgcctttg aagactatga
    31801 tattttcatc tcaacgacct cggcttgttc gtccaaggct gggaaaccag ccggaaccct
    31861 gattgctatg ggagtggaca aggataaggc tcagtcagct gtgcgtctta gtctagacct
    31921 tgaaaatgat atgagtcagg tcgagcagtt cttgaccaag ctaaaattaa tttacaatca
    31981 aactagaaaa gtaagatagg agcattcatg cagtattcag aaattatgat tcgctacggt
    32041 gagctgtcaa ccaagggcaa aaatcgtatg cgtttcatca ataaacttcg caataatatt
    32101 tcagacgttt tgtctatcta tccccaagtt aaggtaacag cagatcgcga ccgtgcccac
    32161 gcttacctca atggagcaga ttacacagca gtagcagaat cgctcaaaca agtatttgga
    32221 attcaaaact tttcccctgt ttataaggtt gaaaaatctg tagaagttct gaagtctgct
    32281 gtccaagaga ttatgcagga catctacaag gaaggcatga cctttaaaat ctctagcaag
    32341 cgtagcgacc acacctttga attggacagt cgtgaactca accaaacgct tggaggggct
    32401 gtattcgaag ccattccaaa cgtacaagct caaatgaaaa gtcctgacat caatcttcag
    32461 gtggagatac gtgaagaagc agcctatctt tcttatgaaa ccgttcgagg ggcaggtgga
    32521 ttaccagtgg gaacttctgg taagggcatg ctcatgttgt cagggggaat cgattcccct
    32581 gtagctggct atctagcgct taaacgaggg gtagatatag aggcagttca ctttgccagc
    32641 ccaccttaca cgagtcctgg tgctcttaaa aaagcccaag atttgacccg taaattaacc
    32701 aaatttgggg gaaatatcca gtttatcgaa gttcctttta cagagattca agaggaaatc
    32761 aaagccaaag cgccagaagc ctaccttatg accttgacgc gtcgttttat gatgcgtatt
    32821 actgaccgta ttcgtgaggt acgaaatggt ttagttatca tcaatgggga aagtctaggt
    32881 caagtagcca gccaaaccct tgaaagtatg aaggctatca atgctgttac caacactccc
    32941 atcattcgtc ctgtggttac catggacaag ttggaaatca ttgacatcgc ccaggaaatc
    33001 gatacctttg acatttcaat ccaaccgttt gaagactgtt gtactatttt tgcaccagat
    33061 cgtccaaaaa caaatcctaa aattaagaat gcggagcagt acgaagcgcg tatggatgtt
    33121 gaaggcttgg ttgagcgagc agtggctgga atcatgatta ctgaaatcac acctcaagcc
    33181 gaaaaagatg aagttgatga cttgattgac aatctgctct aattcagaaa atccaaaaga
    33241 atagcgaaaa tcagtaaaaa aagttagttt tttctctaaa aacaggtaaa aaactaactt
    33301 tttttatttt tatgatataa tgatataaaa ttttgaatat agagagtttt ctgacaatga
    33361 atcaatccta cttttatcta aaaatgaaag aacacaaact caaggttcct tatacaggta
    33421 aggagcgccg tgtacgtatt cttcttccta aagattatga gaaagataca gaccgttcct
    33481 atcctgttgt atactttcat gacgggcaaa atgtttttaa tagcaaagag tctttcattg
    33541 gacattcatg gaagattatc ccagctatca aacgaaatcc ggatatcagt cgcatgattg
    33601 tcgttgctat tgacaatgat ggtatgggga ggatgaatga gtatgcggct tggaagttcc
    33661 aagaatctcc tatcccagag cagcagtttg gtggtaaggg tgtggagtat gctgagtttg
    33721 tcatggaggt ggtcaagcct tttatcaagc acaaaacagg ttggtttgat ggcatgatga
    33781 cgacaggttg ctctatggga gcctatcatg cactcaattt cttcctccag catccagatg
    33841 tctttaccaa agtgattgct ctcagtggtg tttacgacgc acgtttcttt gtcggcgatt
    33901 actacaacga tgatgctatt taccaaaact cgccagtaga ttatatttgg aaccaaaacg
    33961 atggctggtt tattgaccgt taccgtcagg cagagattgt gctgtgtacg gggcttggag
    34021 cctgggaaca agatggttta ccatcctttt acaagctcaa agaagccttt gaccagaaac
    34081 aaattccagc ctggtttgct gaatggggac atgatgtcgc ccacgactgg gaatggtggc
    34141 gtaaacaaat gccttatttc ctcggtaatc tctatttata aaaggagtta cctatgaatt
    34201 accttgttat ttctccctac tatccacaaa actttcaaca gtttaccatc gaactagcta
    34261 ataaaggcat cacagtcttg ggaattggtc aagagtctta cgagcaattg gatgagccct
    34321 tgcgcaatag cttgaccgag tattttcgtg ttgataatct tgagaacata gatgaagtca
    34381 aacgtgcagt tgcttttctc ttttataaac atggtccaat tgaccgcatc gagtctcaca
    34441 atgaatactg gcttgagcta gacgcaacac tcagagaaca attcaatgtt tttggtgcca
    34501 aaccagagga tctcaaaaag acgaaatata agtctgaaat gaagaaactt ttcaaaaaag
    34561 caggtgttcc tgtggtacct ggagctgtta tcaagacgga agcagatgtt gatcaagcag
    34621 tgaaagaaat cggtcttcca atgattgcca aacctgataa tggagtggga gcagccgcaa
    34681 cctttaaact tgagacagaa gacgatatca atcacttcaa gcaagaatgg gaccattcaa
    34741 ccctttattt ctttgaaaaa tttgtcactt ccagcgaaat ctgtaccttt gacgggctcg
    34801 tggacaagga tggaaagatt gtcttctcaa caacctttga ctacgcctat acaccgcttg
    34861 acctcatgat ttataagatg gacaattctt attatgtgct caaggatatg gatcctaaac
    34921 tgcgcaagta tggggaagca attgtcaaag aatttggtat gaaagaacgg tttttccata
    34981 ttgagttctt ccgtgagggg gacgattata ttaccatcga gtacaataac cgccctgcag
    35041 gtggttttac cattgatgtt tataactttg ctcattcctt ggacctttat cgtggctatg
    35101 cagctattgt cgcaggagag gagttcccgg cgtcagactt tgaaactcag tattgtttgg
    35161 ctacttctcg ccgtgcaaat gctcactatg tttattcaga agaggatttg cttgccaaat
    35221 atagccagca gttcaaggtt aaaaaagtca tgccagctgc cttcgcggaa cttcaaggag
    35281 attacctgta tatgctgaca actccgagtc gacaagaaat ggatcagatg attgctgatt
    35341 tcggacaacg tcaagaataa gaactatcgg attaaggaaa ttcactccct taatcctttt
    35401 gttttgtctg gtaaaaaata agagcatcct aacaaggtag ctatcataaa acttgttcga
    35461 taactatttg aagcaggatt aggtggctag aaattgaatt ttaacatttc aatttagtca
    35521 tagtattgtg ttttcgtatc cttaaatcag ctaaaaggat ccatgacgac acctatacga
    35581 tatagttttc aggataccaa accagtctat taatactcaa tgaaaatcaa agagcaaact
    35641 aggaagctag ccgcaggttg ctcaaaacac tgttttgagg ttgtggatag aactgacaga
    35701 gtcagtatca tatacctacg gcaaggtgaa gctgacgtgg tttgaagaga ttttcgaaga
    35761 gtataaaata ttcaggtgac gcatagatat agttaattga agctttgttt gaaatctgat
    35821 aaaataatga tattactaag ttttaaaaac taaagaaaag ggaagatatg attacaggcg
    35881 aattaaaaaa taaaatcgat cagctgtggg aaattctttg gacagaagga aacgcaaatc
    35941 ctttaacaaa tattgaacag ttgacttatc tcttatttat gaaagatttg gatagtgtcg
    36001 agcttggacg tgaaagtgat gctgaatttc tagggattcc ttatgaggga gtttttccaa
    36061 aagataaacc tgaataccgt tggtcaactt ttaaaaatat aggagatgct caggaagttt
    36121 atcgtttaat gactcaggag atttttccgt ttattaaaaa tctcaagggg gatacagatg
    36181 atacagcctt ttcacgatat atgcgagaag ctatttttca aataaataaa cctgctacgc
    36241 ttcaaaaggc aatttctatc ttagatgttt ttccaactag gggattagat gtagattttg
    36301 ataatgacaa acaaagtatt actgatatcg gagatatcta tgaatatctg ttatcaaaat
    36361 tgtcgaccgc aggtaaaaat ggacagttcc gtacacctcg tcacatcatc gatatgatgg
    36421 ttgagttgat gcaaccgact atcaaagata tcatctcaga tcccgctatg ggttctgctg
    36481 gcttcttagt atctgctagc cgttacttaa agcgtaagaa agatgaatgg gaaaccaata
    36541 cagataatat caatcatttt cataatcaga tgtttcatgg aaatgatacg gatacgacta
    36601 tgttgagact tggggcgatg aacatgatgc tacatggagt agaaaatcca caaatcagtt
    36661 accttgactc gctgtctcaa gataatgaag aagccgataa atatactttg gttttagcaa
    36721 atcctccttt taagggctca cttgactaca attcaacctc taatgacctt cttgcaaccg
    36781 taaaaaccaa aaaaacagaa ttactctttc tttctctttt cttgcgaact ttaaaaccag
    36841 gtggacgagc agcagttatc gtacctgatg gtgtcctttt tggttcgtct aaagctcata
    36901 aaggaattcg tcaggaaatt gtagagaatc ataagcttga tgctgtaatc tcaatgccta
    36961 gtggtgtgtt caagccttat gctggagttt caactgccat tctcatcttt acaaaaactg
    37021 gtaatggtgg tactgacaaa gtctggtttt acgatatgaa agcggatggt ttaagtttgg
    37081 atgataagcg acaaccgatt agcgacaatg atattccaga tattatcgaa cgctttcatc
    37141 atcttgaaaa agaagcagaa cgtcagagaa cggatcaatc tttctttgtt ccagttgctg
    37201 agataaagga aaatgattat gatttgtcta tcaataaata taaagagatt gagtatgaaa
    37261 aagttgagta tgaaccaaca gaggtcatct taaagaaaat caatgattta gaaaaagaaa
    37321 ttcaagctgg cttggctgaa ttagaaaaat tactcaagta gggaggtggc tgtatgaaaa
    37381 aagtgaagtt gggggaagtc ttatctctaa aaaaaggcaa gaaagccact gtacttgctg
    37441 aacaaacaac tctaagccaa cgttatattc aaatagatga tttaagaaat aataataatt
    37501 taaaattcac tgaaagttta aatatgactg aagcactccc agatgatatt ctgatagcat
    37561 gggatggagc taatgcagga acagttggtt atggattatc gggagctgtt ggtagtacaa
    37621 ttacggtctt aaaaaagaat gagcgataca aagaaaaaat tatatcagat tacttgggag
    37681 tctttttgga aagtaaatcg cagtatttac gagaacattc aacaggtgca acaattcctc
    37741 atttaaacaa gaatatatta cttgatttac aattagaatt gctaggtatc gaagaacaag
    37801 agaacattat ctgtattctt aatacgatta aagggcttat tactaaaaga aaattgcagt
    37861 tagatgaact aaacttgctc g
//
LOCUS       DAVBOG010000018        37294 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.018, whole genome shotgun sequence.
ACCESSION   DAVBOG010000018 DAVBOG010000000
VERSION     DAVBOG010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 37294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37294
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.018"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..567
                     /locus_tag="VQ865_000951"
     CDS             <1..567
                     /locus_tag="VQ865_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat-containing
                     protein"
                     /protein_id="HET3135304.1"
                     /translation="DAKNPALSPLGENVKTKGQYFYQVALDGNVAGKEKQALIDQFRA
                     NGTQTYSATVNVYGNKDGKPDLDNIVATKKVTIKINVKETSDTANGSLSPSNSGSGVT
                     PMNHNHATGTTDSMPADTMTSSTNTMAGENMAASANKMSDTMMSEDKAMLPNTGETQT
                     SMASIGLLGLALAGLLGGLGLKNKKEEN"
     gene            734..1432
                     /locus_tag="VQ865_000952"
     CDS             734..1432
                     /locus_tag="VQ865_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135305.1"
                     /translation="MGKTILLVDDEVEITDIHQRYLIQAGYQVLVAHDGLEALELFKK
                     KPIDLIITDVMMPRMDGYDLISEVQYLSPEQPFLFITAKTSEQDKIYGLSLGADDFIA
                     KPFSPRELVLRVHNILRRLHRGGETELISLGNLKMNHSSHEVQIGEEMLDLTVKSFEL
                     LWILASNPERVFSKTDLYEKIWKEDYVDDTNTLNVHIHALRQELAKYSSDQTPTIKTV
                     WGLGYKIEKPRGQT"
     gene            1429..2481
                     /locus_tag="VQ865_000953"
     CDS             1429..2481
                     /locus_tag="VQ865_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000769768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HET3135306.1"
                     /translation="MKLKSYILVGYIISTLLTILVVFWAVQKMLIAKGEIYFLLGMTI
                     VASLVGAGISLFLLLPVFTSLGKLKEHAKRVAAKDFPSNLEVQGPVEFQQLGQTFNEM
                     SHDLQVSFDSLEESEREKGLMIAQLSHDIKTPITSIQATVEGILDGIIKESEQAHYLA
                     TIGRQTERLNKLVEELNFLTLNTARNQVETTSKDSIFLDKLLIECMSEFQFLIEQERR
                     DVHLQVIPESARIEGDYAKLSRILVNLVDNAFKYSAPGTKLEVVAKLEKDQLSISVTD
                     EGQGIAPEDLENIFKRLYRVETSRNMKTGGHGLGLAIARELAHQLGGEITVSSQYGLG
                     STFTLVLNLSGSENKA"
     gene            2676..3287
                     /gene="rpsD"
                     /locus_tag="VQ865_000954"
     CDS             2676..3287
                     /gene="rpsD"
                     /locus_tag="VQ865_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014407971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HET3135307.1"
                     /translation="MSRYTGPSWKQARRLGLSLTGTGKELARRNYVPGQHGPNNRSKL
                     SEYGLQLAEKQKLRFTYGVGEKQFRNLFVQATKIKGGILGFNFMLLLERRLDNVVYRL
                     GLATTRRQARQFVNHGHILVDGKRVDIPSYRVTPGQVISVREKSLKVPAILEAVEATL
                     GRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML"
     gene            3472..3627
                     /locus_tag="VQ865_000955"
                     /pseudo
     CDS             3472..3627
                     /locus_tag="VQ865_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            4054..4314
                     /locus_tag="VQ865_000956"
     CDS             4054..4314
                     /locus_tag="VQ865_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135308.1"
                     /translation="MTGVSNPTTDSARLVLAEAKKAFADDSLTEQGLRDILQTVKDAI
                     ASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK"
     gene            4268..4488
                     /locus_tag="VQ865_000957"
                     /pseudo
     CDS             4268..4488
                     /locus_tag="VQ865_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809441.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            4807..5736
                     /locus_tag="VQ865_000958"
     CDS             4807..5736
                     /locus_tag="VQ865_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3135309.1"
                     /translation="MKKFSKTLRDNWIFLLMVLPGTLWLILFFYIPVFGNVVAFKDYH
                     MTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAII
                     LSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFY
                     ADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIP
                     QLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGM
                     AAAAGLYQSVVGLILVILSNLLARRVDPNSALF"
     gene            5750..6673
                     /locus_tag="VQ865_000959"
     CDS             5750..6673
                     /locus_tag="VQ865_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3135310.1"
                     /translation="MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVF
                     VIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNV
                     FITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVP
                     MLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTA
                     LGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMA
                     MVVVATLPIAILYPFFQRYFVKGLTIGGVKE"
     gene            6757..8232
                     /locus_tag="VQ865_000960"
     CDS             6757..8232
                     /locus_tag="VQ865_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000800432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3502 domain-containing protein"
                     /protein_id="HET3135311.1"
                     /translation="MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIK
                     MYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAF
                     ADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQ
                     NFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPV
                     ANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQD
                     TWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEK
                     SMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNW
                     ILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINT
                     GTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK"
     gene            8504..9490
                     /locus_tag="VQ865_000961"
     CDS             8504..9490
                     /locus_tag="VQ865_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001030014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HET3135312.1"
                     /translation="MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADE
                     GINGTVSGDYETTQKYMDYVHSLPGMEELWFKIDEESEQAFKKMFVRYKKEIVHLGLE
                     DNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRN
                     FRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKD
                     PEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILT
                     SEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV"
     gene            9612..10472
                     /locus_tag="VQ865_000962"
     CDS             9612..10472
                     /locus_tag="VQ865_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4299 domain-containing protein"
                     /protein_id="HET3135313.1"
                     /translation="MAKTFFIPNKQSILGEQEILNAKSILALLDGLESHSYDVVYLRQ
                     PLNRLEYIECAIVGQSQFLFKVSYADGQKAYRVDLPDLLTKTDWQIIKSFLDALLAYT
                     GTDIEGLDGFDFEAYFQASIQAYLADPVARFTICQGIFNPIFFSRENLKSFLEADGLA
                     QFEARVRAVQETDAYFARVSFYQDGEGKVHGVYHLAQGVKTVLPREPFVPAAYIEQLV
                     DKEVQWEIDLVQITGDGSKPEDYEAIARLDYAKFLEVLPLSFYHQLDANQIEVQPILD
                     KDFKALAQEE"
     gene            complement(10649..11713)
                     /locus_tag="VQ865_000963"
     CDS             complement(10649..11713)
                     /locus_tag="VQ865_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135314.1"
                     /translation="MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIEK
                     NTQLEEEVPQAEVELESQQEEKIEAPEDSEARTEIEEKKASNSTEEEPDLSKETEKVT
                     IAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIK
                     SPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLT
                     LFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIA
                     SFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIIL
                     LFFVAEVALIGDYLRILAFL"
     gene            complement(11776..12687)
                     /locus_tag="VQ865_000964"
     CDS             complement(11776..12687)
                     /locus_tag="VQ865_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 domain-containing protein"
                     /protein_id="HET3135315.1"
                     /translation="MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPIY
                     DSRTEKLTFGKEVENLEITLHQHALTITDSFDDQIHISYHPSLSAHHDLITNQNDRTL
                     SLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILQLPKGRTLKGINISANRGQTTI
                     INASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAEN
                     IQVHGKVELTAKDYLRIILNQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYK
                     TEKTDVKDQLIARSDDNIDLISTPSRR"
     gene            complement(12680..13273)
                     /locus_tag="VQ865_000965"
     CDS             complement(12680..13273)
                     /locus_tag="VQ865_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HET3135316.1"
                     /translation="MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEEL
                     IASLGTPKEAAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILV
                     TLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGA
                     SSLVLLGISYVARFFGLLIVRLVQFVLKKRKRGNQHA"
     gene            complement(13260..13586)
                     /locus_tag="VQ865_000966"
     CDS             complement(13260..13586)
                     /locus_tag="VQ865_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000273865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3135317.1"
                     /translation="MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLY
                     PILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWALYTDTINGIIEGS
                     IRHDKN"
     gene            complement(13725..14888)
                     /locus_tag="VQ865_000967"
     CDS             complement(13725..14888)
                     /locus_tag="VQ865_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CynX/NimT family MFS transporter"
                     /protein_id="HET3135318.1"
                     /translation="MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSL
                     GVLTSLPLLMFTLFSPFSTRLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLM
                     VGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGL
                     ILLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYT
                     AMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSL
                     AGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLS
                     QTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL"
     gene            14946..16085
                     /locus_tag="VQ865_000968"
     CDS             14946..16085
                     /locus_tag="VQ865_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000096190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3135319.1"
                     /translation="MSSKVSGFQDKNGKVLKIMIEWWKGKFRRVVVTQNVESLLVSIV
                     ISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDAEFNSIR
                     LYNNPKKNQASGFNLGVKHSVGGLILKIDAHSKVTESFVMNNVAVIQQGEFVCGGPRP
                     TIVKGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNE
                     QLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQ
                     FKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLSLLTLLTLLKHK
                     NGFLIVMPFLLFSIHFAYGLGTIVGLIRGFKWKKEYKGTVIYLEK"
     gene            16153..18003
                     /locus_tag="VQ865_000969"
     CDS             16153..18003
                     /locus_tag="VQ865_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HET3135320.1"
                     /translation="MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILF
                     YGLINPAPVDYIIYTSLAFLFYQLMVDFWGLSASISRYSKITDFMKIFFGVTASSVLS
                     YSICYAFLPLFSIRFIILFILLSAFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGA
                     GDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIER
                     VIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGR
                     QEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVY
                     HELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFK
                     NNIRGTYNVARAVDEAKVPKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTY
                     CAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAK
                     DGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVD
                     NQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE"
     gene            complement(18182..18280)
                     /locus_tag="VQ865_000970"
                     /pseudo
     CDS             complement(18182..18280)
                     /locus_tag="VQ865_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(18306..18938)
                     /locus_tag="VQ865_000971"
     CDS             complement(18306..18938)
                     /locus_tag="VQ865_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000200889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3135321.1"
                     /translation="MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIR
                     GFMGPPLESSFATCLSKDQISEAMQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPL
                     YITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIII
                     GDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ"
     gene            complement(18960..19832)
                     /gene="sdaAA"
                     /locus_tag="VQ865_000972"
     CDS             complement(18960..19832)
                     /gene="sdaAA"
                     /locus_tag="VQ865_000972"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000500050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HET3135322.1"
                     /translation="MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLME
                     RNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNE
                     HNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASI
                     SGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEV
                     PCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLAT
                     TPTGRRLQKEIFGE"
     gene            complement(19841..20512)
                     /gene="sdaAB"
                     /locus_tag="VQ865_000973"
     CDS             complement(19841..20512)
                     /gene="sdaAB"
                     /locus_tag="VQ865_000973"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015606087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HET3135323.1"
                     /translation="MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPT
                     EVEFQLFNSFAKTYRGHGTDLALVAGILGMDTDDPEIPNSLEIAHKRGIKIVWTIQKD
                     SNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDI
                     PGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHN
                     VNFFK"
     gene            20754..21326
                     /locus_tag="VQ865_000974"
     CDS             20754..21326
                     /locus_tag="VQ865_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HET3135324.1"
                     /translation="MKSITKKIKATLAGVAALFAVFSPSFVSAQESSTYTVKEGDTLS
                     EIAETHNTTVEKLAENNHIDNIHLIYVDQELVIDGPVAPVATPAPATYAAPAAQDETV
                     SAPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAE
                     NQERVADAYVAGRYGSWTAAKNFWLNNGWY"
     gene            complement(21378..21698)
                     /locus_tag="VQ865_000975"
     CDS             complement(21378..21698)
                     /locus_tag="VQ865_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3135325.1"
                     /translation="MQRLEVYKNYQHLYDLQIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVEIYYQ
                     AKER"
     gene            22123..22407
                     /locus_tag="VQ865_000976"
     CDS             22123..22407
                     /locus_tag="VQ865_000976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001230165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactococcin 972 family bacteriocin"
                     /protein_id="HET3135326.1"
                     /translation="MRKLVKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFG
                     YSDYLHSTRSHTATVKDGNKFSKDRAEAEAWARASIFKFPPTGMEYFYGF"
     gene            22462..24570
                     /locus_tag="VQ865_000977"
     CDS             22462..24570
                     /locus_tag="VQ865_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000723955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
                     /protein_id="HET3135327.1"
                     /translation="MKKISHLCMLLLLLCTTFFVFNVNYTREVVRIQEMGKTVDSLDL
                     YLKDINEPAASVLRFFEDVSKEYKVSIIKTDSGDEVVKSGVFDKDTFPYQEFGISSLD
                     FTTDGEGVYSNKEISNKLGTIPTFLKAKPIQLMTFQTYIKDTSRSLNGRYTITSTQEM
                     DKDRIVQKWSDFFKIDQATLLEPTYKSAVEVINRDLLLSAIVFVLAILLLVLVTVYQP
                     MMEMKRVGVQKLLGFQDRAVLADVVKGNLYLLLGGALVINLGVFFLLDYKPKDLFPML
                     WLSHFLLLQLYLFISWLTYLLIQKMTISSLLKGFSSFKFGLLFNYLMKIGTTILLTVL
                     LVGVGKSLEQENKELDYQKQWISQGNYLTLETFQLNDNLWQEQLAGSGKALDYFYRFY
                     QDLVEKTQAGYVQSSSLPVKNFVQSEQIQQYQLTDTVDVYYANRNFLKSKGFKLPDTG
                     IKKVILMPASTKGEEDKNQLLGKLIAFHSMKYEEQQKRTIEEMDVEIAYYEGDWSFFP
                     YSDKRKENLSNPIISLVNDSDMMWDEKASLSTTGLNNPIKIENTVQHQKEITELVEKL
                     SDGNYLKFSSIQAIQQEKVDSYRDAVRNFNLLFALFGLLSMMISYFLLVITFLLKRRD
                     IITKKFMGWKLVDRYRPLLVLLLLGYSFPLLVLIFFAHAFLPLLLFAGFTCLDILFVL
                     VLASRMEKRSLVELLKGGIL"
     gene            24567..25208
                     /locus_tag="VQ865_000978"
     CDS             24567..25208
                     /locus_tag="VQ865_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000571330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135328.1"
                     /translation="MIELENITKTIGGKVILDHLSLRIDQGDLVAIVGKSGSGKSTLL
                     NLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREHISYLFQNFALIDDETVEYNLML
                     ALKYVKLSKKDKLKKVEEILERVGLSSTLHQKVSELSGGEQQRIAVARAILKPSQLIL
                     ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRIIELGEGK"
     gene            25415..26221
                     /locus_tag="VQ865_000979"
     CDS             25415..26221
                     /locus_tag="VQ865_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3135329.1"
                     /translation="MNKMKKVLMTMFGLVMLPLLFACSNNQSAGIEAIKSKGKLVVAL
                     NPDFAPFEYQKVVDGKNQIVGSDIELAKAIATELGVELELSPMSFDNVLASVQSGKAD
                     LAISGVSKTDERSKVFDFSIPYYTAKNKLIVKKSDLTTYQSVNDLAQKKVGAQKGSIQ
                     ETMAKDLLQNSSLVSLPKNGNLITDLKSGQVDAVIFEEPVSKGFVENNPDLAIADLNF
                     EKEQDDSYAVAMKKDSKELKEAVDKTIQKLKESGELDKLIEDAFKASIEK"
     gene            26187..26657
                     /locus_tag="VQ865_000980"
     CDS             26187..26657
                     /locus_tag="VQ865_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HET3135330.1"
                     /translation="MRMPLKHPLKNRKKEKNMSKEKVILAYSGGLDTSVAITWLKKDY
                     DVVSVCMDVGEGKDLDFIHDKALKVGAVESYVIDVKDEFATDYVLVALQSHAYYEQKY
                     PLVSALSRPLISKKLVEIAHQTGATTIAHGCTGKGNDQVEYQIAVAKKANEAKK"
     gene            complement(26947..27267)
                     /locus_tag="VQ865_000981"
     CDS             complement(26947..27267)
                     /locus_tag="VQ865_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3135331.1"
                     /translation="MQRLEVYKNYQHLYDLRIAILLNLSTLYLYNQDKNMCKQICYTL
                     LEDAKNKKSYDRLAICYVRIGICTDDSKLIQKGFSLLELTEETSMLSHLKKEVETHYQ
                     PKKL"
     gene            28031..28411
                     /locus_tag="VQ865_000982"
     CDS             28031..28411
                     /locus_tag="VQ865_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0115 family bacteriocin-like peptide"
                     /protein_id="HET3135332.1"
                     /translation="MELVLPNNYVALEQEEMMYLDGGGVGRNWWNSRGSFATVLDVGL
                     AIYSGGATIYSAYAIKKAISANRGAITRTLRSLIIKHVGSAAGHLVNTALNVALTVTG
                     FSLGGAIAYGADWADGSLDGYIFA"
     gene            28785..29843
                     /locus_tag="VQ865_000983"
     CDS             28785..29843
                     /locus_tag="VQ865_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135333.1"
                     /translation="MKDDQKYLLAGLYSLLVAIFYFPLIESKGIFVSILMAVLLLYLI
                     YFIGTVIHIVIIKFIRKKSFKYLVLYPFTYDGSWRFQPINLLYFPEMVRDVIPINLVQ
                     EYCQGQPYGLLKKMLKRIRLSREIALLLATIIVYFFTHRILPLSVFTFMFSYILIFAQ
                     SYLGGNTAWIGNRRLIIDDEFEKILLSKSYIKEISSARYSEYLTCEYKNLTPIILLAI
                     FENLLDSYLLQNQSEVDLDIFYKVLPLLYKEKYTMGFNYFVSLNYLLYKVGFLGIIYD
                     NEALGDLSKQYLNRNISELQDGSFEGGIQDAVASKQIVVINEFIACLNSRCMPSQYDR
                     FFYKDRPYIFSRKSPIKR"
     gene            30158..31134
                     /locus_tag="VQ865_000984"
                     /pseudo
     CDS             30158..31134
                     /locus_tag="VQ865_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001837003.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            31511..31885
                     /locus_tag="VQ865_000985"
     CDS             31511..31885
                     /locus_tag="VQ865_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPH_0224 family bacteriocin-like peptide"
                     /protein_id="HET3135334.1"
                     /translation="MELVLPNNYVALEQEEMMYFDGGFSIPRWPVATAINIAFNDVLG
                     GGAISLVRNYIRNYGLRRVTSAIAGAAARYVGVRVANRVAGFALSAINGFAAWMSIGN
                     AITTIWANNDVNRRDPNLNALW"
     gene            32093..32995
                     /locus_tag="VQ865_000986"
     CDS             32093..32995
                     /locus_tag="VQ865_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000619809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135335.1"
                     /translation="MIRKLIIFLLMLPLFVLWLELHVLVNNLLLNLESPLDFVISMSL
                     AFCSLILSKIVLDILYALKDLYKKEALITIFPFIFIGRKKVNVRFSPYFSFHRKSLSP
                     DDLRSRIIWSFILEIAIILVFILKIPFAIIMLTTIFFWTIMDINHLVFNKTEFLFNQN
                     KWQKEDSFESDLTKTLKDKIQKSELSYSDLMSLQLYDAMNQSTFLTDSELFEDILKKI
                     EDSHNTLLCTGLVELLLYEISISNNNNWQEKVDKIRIQLIRINQLDFFYYTSWLRQNF
                     DFCMNREYHKMKSRKLLLSNKKIV"
     gene            33051..33404
                     /locus_tag="VQ865_000987"
     CDS             33051..33404
                     /locus_tag="VQ865_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000424445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HET3135336.1"
                     /translation="MELVLPNNYVVIDEEEMMYLDGEAYLSKRACQGICAALAMSSGT
                     FIALAGAAVLTKKLINYIKVGGLGGWLIGAAAGVLATAAGKIAYYIGYGVLNRGCDIN
                     GNPYPWDGFISATVK"
     gene            33401..34129
                     /locus_tag="VQ865_000988"
     CDS             33401..34129
                     /locus_tag="VQ865_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135337.1"
                     /translation="MSNVDKIRKIHIIVCWMYIFLSFRAIINDTEYFLLIFLAFIYSI
                     VSLPLYSVKNKIVSICLAINSILLMSFPILINKFFPESFLTYTVLISVFITELIIFHL
                     IGKDFDIKLTNEYKKISQFRSKVSQSPWIKYLEISSFILTIFPSILYGTVDNHVLTLI
                     FLIKICADTTIKFLFIRLFDTSTLMKRRIFFLFALDVIAYLFLGYLLVIQKAGYLFSV
                     LLLFSNFSVPFIKEKEFELFKNSK"
     gene            35261..35500
                     /locus_tag="VQ865_000989"
     CDS             35261..35500
                     /locus_tag="VQ865_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135338.1"
                     /translation="MKLLDCILDYQERFNGKTCQVSTNYKYLETFKVNFCLTDLHHLF
                     DLHKITRDYASQTKPAIQAGVFILEDFRNILCTMM"
     gene            36050..>37294
                     /locus_tag="VQ865_000990"
     CDS             36050..>37294
                     /locus_tag="VQ865_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001035309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein"
                     /protein_id="HET3135339.1"
                     /translation="MNKKKMILTSLASVAILGAGFVASQPTVVRAEEAPVASQSKAEK
                     DYDAAKRDAENAKKALEEAKRAQKKYEDDQKKTEEKAKKEKEASKEEQAANLKYQQEL
                     VKYASEKDSVKKAKILKEVEEAEKEHKKKRAEFEKVRSEVIPSAEELKKTRQKAEEAK
                     AKEAELIKKVEEAEKKVTEAKQKLDAERAKEVALQAKIAELENEVYRLETELKGIDES
                     DSEDYVKEGLRAPLQSELDAKRTKLSTLEELSDKIDELDAEIAKLEKNVEYFKKTDAE
                     QTEQYLAAAEKDLADKKAELEKTEADLKKAVNEPEKPAEETPAPAPKPEQPAEQPKPA
                     PAPQPAPAPKPEKTDDQQAEEDYARRSEEEYNRLPQQQPPKAEKPAPAPKPEQPVPAP
                     KTGWKQENGMWYFYNTDGSMATG"
BASE COUNT        11695 a         6297 c         7786 g        11516 t
ORIGIN      
        1 gacgctaaaa acccagccct atctccacta ggcgaaaacg tgaagaccaa aggtcaatac
       61 ttctatcaag tagccttgga cggaaatgta gctggcaaag aaaaacaagc gctcattgac
      121 cagttccgag caaacggcac tcaaacttac agcgctacag tcaatgtcta tggtaacaaa
      181 gacggtaaac cagacttgga caacatcgta gcaactaaaa aagtcactat taagataaat
      241 gttaaagaaa catcagacac agcaaatggt tcattatcac cttctaactc tggttctggc
      301 gtgactccga tgaatcacaa tcatgctaca ggtactacag atagcatgcc tgctgacacc
      361 atgacaagtt ctaccaacac gatggcaggt gaaaacatgg ctgcttctgc taacaagatg
      421 tctgatacga tgatgtcaga ggataaagct atgctaccaa atactggtga gactcaaaca
      481 tcaatggcaa gtattggttt acttgggctt gcgcttgcag gtttactcgg tggtctaggt
      541 ttgaaaaaca aaaaagaaga aaactaatca gctaaggaaa taaatgatgg atagtgggct
      601 gactaagatt agtttaacaa ctcaatcagc aatcaggact ttctttcaat agcagattaa
      661 aatcatcgta aaacaataaa aatagtgtta tacttaaagc agtatagcac tgtttttatc
      721 aaaggagaga cagatgggaa agacaatttt actcgttgac gacgaggtag aaatcacaga
      781 tattcatcag agatacttaa ttcaggcagg ttatcaggtc ttggtagccc atgatggact
      841 ggaagcgcta gagctgttca agaaaaaacc gattgatttg attatcacag atgtcatgat
      901 gcctcggatg gatggttatg atttaatcag tgaggttcaa tacttatcac cagagcagcc
      961 tttcctattt attactgcta agaccagtga acaggacaag atttacggcc tgagcttggg
     1021 agcagatgat tttattgcta agccttttag cccacgtgaa ctggttttgc gtgtccacaa
     1081 tattttgcgc cgccttcatc gtgggggcga aacagagctg atttcccttg gcaatctaaa
     1141 aatgaatcat agtagtcatg aagttcaaat aggagaagaa atgctggatt taactgttaa
     1201 atcatttgaa ttgctgtgga ttttagctag caatccagag cgagttttct ccaagacaga
     1261 cctctatgaa aagatctgga aagaagacta cgtggatgac accaatacct tgaatgtgca
     1321 tatccatgct cttcgacagg agctggcaaa atatagtagt gaccaaacgc ccactattaa
     1381 gacagtttgg gggttgggat ataagataga gaaaccgaga ggacaaacat gaaactaaaa
     1441 agttatattt tggttggata tattatttca accctcttaa ccattttggt tgttttttgg
     1501 gctgttcaaa aaatgctgat tgcgaaaggc gagatttact ttttgcttgg gatgaccatc
     1561 gttgccagcc ttgtcggtgc tgggattagt ctctttctcc tattgccagt ctttacgtcg
     1621 ttgggcaaac tcaaggagca tgccaagcgg gtagcggcca aggattttcc ttcaaatttg
     1681 gaggttcaag gtcctgtaga atttcagcaa ttagggcaaa cttttaatga gatgtcccat
     1741 gatttgcagg taagctttga ttccttggaa gaaagcgaac gagaaaaggg cttgatgatt
     1801 gctcagttgt cgcatgatat taagactcct atcacttcga tccaagcgac ggtagaaggg
     1861 attttggatg ggattatcaa ggagtcggag caagctcatt atctagcaac cattggacgc
     1921 cagacggaga ggctcaataa actggttgag gagttgaatt ttttgaccct aaacacagct
     1981 agaaatcagg tggaaactac cagtaaagac agtatttttc tggacaagct cttaattgag
     2041 tgcatgagtg aatttcagtt tttgattgag caggagagaa gagatgtcca cttgcaggta
     2101 atcccagagt ctgcccggat tgagggagat tatgctaagc tttctcgtat cttggtgaat
     2161 ctggtcgata acgcttttaa atattctgct ccaggaacca agctggaagt ggtggctaag
     2221 ctggagaagg accagctttc aatcagtgtg accgatgaag ggcagggcat tgccccagag
     2281 gatttggaaa atattttcaa acgcctttat cgtgtcgaaa cttcgcgtaa catgaagaca
     2341 ggtggtcatg gattaggact tgcgattgcg cgtgaattgg cccatcaatt gggtggggaa
     2401 atcacagtca gcagccagta cggtctagga agtaccttta ccctcgttct caacctctct
     2461 ggtagtgaaa ataaagccta aaaccccttt acaaatccag ctattcatgg tagaatggat
     2521 tttgtgtgaa atatcagcag gaaagcatga agctcgtcaa caggtgtctt atgataagta
     2581 accttggctg tttaggcgaa gggcatctgc acgaatcagg gctttctaag tgactatttc
     2641 caccgaaata ttatttatat caggaggaca ttcatatgtc acgttataca ggaccatctt
     2701 ggaaacaagc tcgtcgcctt ggcctttcac ttacaggtac aggtaaagaa ttggcacgtc
     2761 gtaactacgt accaggacaa cacggaccaa acaaccgttc taaattgtca gaatacggtt
     2821 tgcaattggc tgaaaaacaa aaacttcgtt tcacttacgg tgtaggtgaa aaacaattcc
     2881 gtaacttgtt cgtacaagct acaaaaatca aaggtggaat cctaggtttc aactttatgc
     2941 ttcttttgga acgtcgtttg gataatgttg tttaccgtct tggtctcgcg actactcgtc
     3001 gtcaagctcg tcaattcgta aaccacggtc acatccttgt tgacgggaaa cgcgttgata
     3061 tcccatcata ccgcgtaact ccaggtcaag tgatctcagt tcgtgaaaaa tcattgaaag
     3121 ttccagcaat ccttgaagca gtagaagcta ctcttggacg tccagcattc gtatcattcg
     3181 acgctgaaaa gttggaaggt tcattgactc gcttgccaga acgcgacgaa atcaacccag
     3241 aaatcaacga agcacttgtc gttgaattct acaacaagat gttgtaatat tttattgaat
     3301 aagacaggct ttgaggcctt gatattaagc actttgggac gttctccctt agtgcttttt
     3361 tgatttctct tagtatccag ctataatcgt tgagacataa ctagaccgat atagtccaaa
     3421 gtgatatagt aaaatgaacc aaaaatagta cacaatgtgg tataatcttt tatggcatat
     3481 tcaatagatt ttcgtaaaaa agttctctct tattgtgagc gaacaggtag tataacagaa
     3541 gcatcacacg ttttccaaat ctcacgtaat accatttatg gctggttaaa gctaaaagag
     3601 aaaacaggag agctaaacca ccaagtatag tgtattgaat ttataacagt acaccttggc
     3661 tgctaaaata tttctataaa ttaatttgac tttcctgata gagttgttca catcttattt
     3721 caaatcacta taaaagctct ataatctctt tattaagatt tgcccatcag acgaaatata
     3781 atggattgaa actagaatag tacacatcta cttctaaaac attgttagaa atcgatttga
     3841 ctgtcctgat cgatttgtcc tgttcttgtt tcattttact atagaacgat ttgaaggcgt
     3901 ttatgatatt tagctgtacg agagtctttt aaaagtgttt tgatagtttg gatttcttct
     3961 ttagttgatt tcatatcact gttatataat gctttttgat tttagtctag tattagtaag
     4021 cagactcaaa ccttagaaaa tcttttgaga tcattgacag gtgtatcgaa tcctaccaca
     4081 gattcagcac gtctggtttt ggcagaggct aagaaagctt ttgcagatga tagtttgaca
     4141 gagcaaggtt tacgtgatat tttgcaaaca gtcaaagatg ccattgcttc cctagagtcc
     4201 attaaggaaa gccagtcagc aactaaggat ggaggacaaa cagcgggcaa agaaacagca
     4261 ggagaagatg agtctgcaaa tcaaactcaa gaaattagcc aaggaattaa gtaaacttct
     4321 taaagactca aaccttgaaa cagtagataa ggatgtcctt gaaaactctc aaaaagaact
     4381 tcaaaaagca gttttgttct tggcagatga aaaagctctg agcatactga agcagaggtg
     4441 attgataatc ttaaagaggt tattgctaag ttgaaagcaa acgcctaata acatattaaa
     4501 aatctccaga ttaggaacta tctctgagtt ccctagtctg gagatttttc agtatacccc
     4561 gttgttggat gcttataaca gagtgacgcc atcactgggc taatagagat aaaataaaca
     4621 attgatttag gacatttgtt tgatagtggt gataaagttt taaatctgct acataatttg
     4681 tggagttttt tctataatta ggagtttaac ctaacctgca aataggagta tactaataat
     4741 gtaatcgtta tcaaaagtct aaaaaagaat ttttagatgg atatcaaaat aaaaagggag
     4801 gaaattatga aaaagttttc aaaaacattg agagacaact ggatctttct cttgatggtt
     4861 ttgccaggga cactctggtt gattctattc ttttacattc cagtatttgg gaacgtggtt
     4921 gccttcaaag actaccacat gaccagtaat ggtttcatag atagtatcat aaatagtaaa
     4981 tgggtcggac tcgataattt cagattctta tttagttcaa gagacgcctt tattatcaca
     5041 cgaaatactg tcctctacaa tcttggcttt atctttctag gtttagttgt atctgtaggg
     5101 attgccatta tcctcagcga gctccgttct aagagaatgg tgaagatttt ccaaacttct
     5161 atgttgttcc cttacttctt gtcttgggtt atcatcagtt tctttacaga tgccttccta
     5221 aatattgata aaggggtgtt caatcatcta ttggaaagtc ttggtctcaa agaagtcaat
     5281 ttttacgctg acctgggcat ctggccctat ctcctacttt tcctaggtat ttggaaaggc
     5341 tttggatata gcagtgtcat gtactatgcg acgatcatgg gaattgatcc aacctactac
     5401 gaagcagcga cagtggacgg agctagcaag tggcaacgta ttcgcaacgt aaccattcct
     5461 cagttgactc cgcttgtaac tgtattgacc atccttgcag tcggaaatat cttccgcgca
     5521 gactttggtc tcttctatca aatcccacac aatgctggtc agctttacaa tgtaaccaac
     5581 gttttggacg tatatgtctt taatggtttg actcagacag cagatatcgg tatggctgca
     5641 gcagccggtc tttaccaatc cgttgttggt ttgattctgg ttatcctatc aaacttgctt
     5701 gcaagacgag tcgatccaaa ctcagctttg ttctagaaag gaggagaata tggcaaaaaa
     5761 gaaaattaaa aaagaaaaaa ttgataatgt cggcattcac tccttcagta agaaagcaga
     5821 tatcttcttc agtatcattt cgggtttgat tgccctctct tgtatcctac cttttgtatt
     5881 cgttatcatt atttcagtga cagacgagaa aagcctcctc caatacggct atagcttctt
     5941 cccatcccaa tttggcttag acggttttga gtttttggca cagtttaagg ataaaatcct
     6001 acaagccctc ttcatctctg tctttgtaac cgtagttggg acattgacaa atgtctttat
     6061 cacaacaacc tatgcctacg ctatttcacg gacaaccttt aagtatcgca gattttttac
     6121 catcttcgtc cttctcagta tgttgttcaa cgctggtttg gtaccaggtt atatcatggt
     6181 gacccgtgta cttcagcttg gtgacactgt ttgggccttg attgttccaa tgcttctctc
     6241 accattcaat atcatcttga tgcgttcctt cttcaagaag accattccag aagccattct
     6301 cgaatcggct cgtatcgatg gtgccagtga ggcccggatt ttcttccaaa tctgtttgcc
     6361 attgtcacta ccaggtatcg caaccatcac gcttttgaca gctcttggtt tctggaatga
     6421 ctggttcaac gcccttcttt acatcaagag tgataacttg tatccattgc aatatttgct
     6481 catgcaaatc caacaaaata tggactacat tgccaaagcg gtcggcttga ctggtcaact
     6541 gggagttgct ctaccgaaag aaacaggtcg tatggccatg gttgtggtag caacccttcc
     6601 aatcgcgatt ttgtatccat tcttccaacg ctactttgta aaaggtttga ctatcggtgg
     6661 tgtgaaagaa tagcacttgt ttccaaactt cccttgcgtg aagttaagat cattacattg
     6721 tttataagtt taaaaataaa aaaaggagtt tttatcatga aaaactggaa aaaatatgct
     6781 tttgcatctg ctagtgtagt tgctttggct gcaggtcttg ctgcttgtgg caacttgaca
     6841 ggtaacagca aaaaagctgc tgattcaggt gacaaacctg ttatcaaaat gtaccaaatc
     6901 ggtgacaaac cagataactt ggatgaattg ttagcaaatg ccaacaaaat catcgaagaa
     6961 aaagttggtg ctaaattgga tatccaatac cttggctggg gtgactatgg taagaaaatg
     7021 tcagttatca catcatctgg tgaaaactat gatatcgcct ttgcagataa ctatattgta
     7081 aatgctcaaa aaggtgctta tgctgacttg acagaattgt acaaaaaaga aggtaaagac
     7141 ctttacaagg cacttgatcc agcttatatc aagggtaata ctgtaaatgg taagatttac
     7201 gctgtaccag ttgcagccaa cgtagcatca tctcaaaact ttgccttcaa cggaactctc
     7261 cttgccaaat atggtatcga tatttcaggt gttacttctt acgaaactct tgagccagtc
     7321 ttgaaacaaa tcaaagaaaa agctccagac gtagtaccat ttgctattgg taaagttttc
     7381 atcccatctg ataactttga ctacccagta gcaaacggtc ttccattcgt tattgacctt
     7441 gaaggcgata ctactaaagt tgtaaaccgt tacgaagtac ctcgtttcaa agaacacttg
     7501 aagactcttc acaaattcta tgaagctggc tacattccaa aagacgtcgc aacaagcgat
     7561 acttcctttg accttcaaca agatacttgg ttcgttcgtg aagaaacagt aggaccagct
     7621 gactacggta acagcttgct ttcacgtgtt gccaacaaag atatccaaat caaaccaatt
     7681 actaacttca tcaagaaaaa ccaaacaaca caagttgcta actttgtcat ctcaaacaac
     7741 tctaagaaca aagaaaaatc aatggaaatc ttgaacctct tgaatacgaa tccagaactc
     7801 ttgaacggtc ttgtttacgg tccagaaggc aagaactggg aaaaaattga aggtaaagaa
     7861 aaccgtgttc gcgttcttga tggctacaaa ggaaacactc acatgggtgg atggaacact
     7921 ggtaacaact ggatccttta catcaacgaa aacgttacag accaacaaat cgaaaattct
     7981 aagaaagaat tggcagaagc taaagaatct ccagcgcttg gatttatctt caatactgac
     8041 aatgtgaaat ctgaaatctc agctattgct aacacaatgc aacaatttga tacagctatc
     8101 aacactggta ctgtagaccc agataaagcg attccagaat tgatggaaaa attgaaatct
     8161 gaaggtgcct acgaaaaagt attgaacgaa atgcaaaaac aatacgatga attcttgaaa
     8221 aacaaaaaat aatcagctaa attgatttcg tgtattcatt cctaactcct aaaataagaa
     8281 tcactgcttt cctcaggttg gtctggggga gacagtggtt tttttggcac aaggatatag
     8341 atatccatgt tttctcttgt ccttatttta accattcagg aaatttcgag aaccctctac
     8401 aatttccagt caaataaatt gcattcgttt tctcaagcag gtatactagt gtagataaat
     8461 aaaaaattta gaaaatttaa gaatagaaaa gagaacaaat cttatggcaa aagatattcg
     8521 tgtcttactt tactaccttt atactccaat tgaaaatgca gagcaatttg ctgcagacca
     8581 cttggctttc tgtaaatcaa tcggtcttaa aggccgtatc ctagtcgctg acgagggaat
     8641 taacggaaca gtttcaggtg actatgaaac aactcaaaaa tacatggact acgttcacag
     8701 ccttccagga atggaagaac tctggttcaa gattgacgaa gaaagtgaac aagccttcaa
     8761 gaagatgttt gttcgctaca agaaagaaat tgtccacctt ggtttggaag acaacgactt
     8821 tgacaatgac atcaacccac ttgaaacaac aggtgcttac ttgtctccaa aagagttcaa
     8881 agaagcgctt cttgataaag ataccgttgt ccttgacaca cgtaatgatt atgagtatga
     8941 cctaggacat ttccgtgggg ctattcgccc agatattcgc aacttccgtg agttaccaca
     9001 atgggtccgt gataacaagg aaaaattcat ggacaagcgt gtcgtggttt actgtacagg
     9061 tggcgttcgc tgtgagaaat tctcaggctg gatggttcgt gaaggttaca aagatgtcgg
     9121 ccaattgcac ggaggaatcg caacttacgg taaagaccca gaagttcaag gtgagctttg
     9181 ggatgggaaa atgtacgtct ttgacgagcg tattgccgtt gatgtcaacc atgtcaaccc
     9241 aactatcgta gggaaagact ggtttgatgg aacaccatgt gaacgttatg tcaactgtgg
     9301 aaatccattc tgtaaccgtc gtatcttgac atcagaagaa aatgaagaca agtaccttcg
     9361 tggatgctca cacgagtgcc gtgttcaccc acgtaaccgc tatgtttcaa aaaatgaatt
     9421 gacacaagct gaagtgattg agcgcctagc cgctatcggt gaaagcttgg atcaagcagc
     9481 tactgtataa gatcaaacag tcctcagggg ctgtttttct atgctttgta ctcaaaaatc
     9541 taaagtttgt ttctgtatct ttcagaaaaa taaggtatac tgtatgtaaa cgatttcaaa
     9601 ggagtccagt tatggcaaaa acatttttta ttccaaataa acagagcatt ttaggagaac
     9661 aagagatttt gaatgccaag tcgatcttgg ccttgctaga cggtttggag tcacatagct
     9721 atgatgtagt ctatctccgt cagcctctta atcgtctcga gtatattgag tgtgcgatag
     9781 tggggcaatc acaatttctt tttaaggtca gttatgctga tggtcaaaag gcttaccgtg
     9841 tcgatcttcc tgacctacta acaaagacag actggcagat tatcaagtca tttttagatg
     9901 ctttgcttgc ttatacaggg actgatattg aagggctaga tggttttgat tttgaagctt
     9961 atttccaagc aagtattcaa gcctatctag cagaccctgt agctcgtttt acgatttgcc
    10021 aaggaatttt taatcctatt ttctttagtc gtgagaactt gaaaagcttt ttagaggcag
    10081 atggcttggc tcagtttgaa gcgcgtgtgc gtgcggttca agagacagat gcctactttg
    10141 cgagagtttc cttctatcag gatggagaag gaaaagtgca tggcgtttac catctagctc
    10201 aaggagtcaa gacagtttta ccgagagaac cgtttgttcc tgcagcctat attgagcaat
    10261 tggtggataa ggaagtgcag tgggagattg acttggttca aatcacagga gatggctcta
    10321 aaccagaaga ctatgaagcc attgcccgct tggactatgc aaaattctta gaggtattac
    10381 ccctatcttt ttaccaccaa ctagacgcca atcaaataga agtgcaaccc atattagaca
    10441 aagattttaa agcattagca caagaagagt aaagcagaag caggtcaatc gacttgcttt
    10501 tttgaaatag aaaaatcctg ccatgaaaga caggattgct actcaatgaa aatcaaagag
    10561 caaactagga agctagccgc aggctgtact tgagtacggt aaggcgaagc tgacgtggtt
    10621 tgaatttgat tttcgaagag tatgaagttt aaagaaaggc caagatacga agataatctc
    10681 caatcagtgc cacttcagct acaaagaaga ggaggataat aactccgttc acaaggacag
    10741 acaagaataa ttgatagaag gagtcggttt cacttgcttg acttggtctt gtaatgatat
    10801 ggagactggc aagcagaatg attccaatgc taatcacaca caagagggct gtaaatcgta
    10861 ggctatcaaa gaaagcaaag aaactagcaa tagcagtgag gaagattgga attgctaaga
    10921 gttgactata ttgttggaga accttgtcta gcgtccagtc cttttcctgg tggataaatc
    10981 gtctcacaac gaaactaccc aagaggaatg aaaagaagaa gagtgttgtc gctactagga
    11041 tagagatgat agaaaaaaga gttaaaggag ctagctgctc agggaagcga ctgttaatgc
    11101 ttgctatatg tccatagtaa gcatgtttga tgtgatagat actaaagaaa aaggaagatg
    11161 cagaaaacag aatgagcaag agaaaggctg tgtaactgtg tgtgatactt gtttccaact
    11221 tacttgtagg agatttgatc gcttccacta gccaagacca aaaatcaagc acttgctctt
    11281 tccatttatc cctagatttt ggagcttggt cggggatata aggactttct aaagatttac
    11341 tgataagaag tggctctttc gtggttgctt tttgctgagg aagagcttct tggctctctt
    11401 cagctatagt gactttttct gtttctttag aaaggtctgg ctcttcttca gtagaattag
    11461 atgccttctt ttcttctatt tctgttctcg cttcactgtc ttcaggagct tcaattttct
    11521 cttcttgctg gctttccaat tcgacttcag cttgagggac ttcctcctct aactgagtat
    11581 ttttttcaat tggtgtatcg agatcggcta tcgtttcttc agccttgtct gcaacctctt
    11641 gagcttgctc ttcaggcttg ttcttgcttg ttgtttttac aaaatcatta ctttcaaacc
    11701 attcttgttt catggtagaa cctccttttt agttagataa atatgcttcc atagtagcag
    11761 atgtaagcgt ttttgtcaac gtctgcttgg tgtggatatt agatcaatat tatcatcaga
    11821 tctcgcaatg agttgatcct tgacatcggt tttttcagtt ttgtaagggt tgcttaattc
    11881 cgtacctctt gattcaggct tttctcttgt gaattggaag atagaaccat agttgcttga
    11941 gatgtcccag ttaattcgtt ggctttcttt ctggtttagg atgattctga gataatcttt
    12001 ggcagtcagt tcaaccttgc catggacttg gatattttca gcgtggaagt gattctctgt
    12061 tgactctagc tgactatctg taagaactgt atcaaagata ttaacgatat tgggcgttgt
    12121 gagtttactg tttttgatac gacttccttc aattcggagg atatagctgt ttgtattgag
    12181 ggtcgcattt tcaaggctag catttatgat ggtggtttgt ccgcgattgg ctgagatgtt
    12241 gatccctttt agagttctcc cttttggtag ctggagaata acttcttcaa aacgactaga
    12301 gtagctactt gcgatatgaa gaatcccacc aattccagaa gagagaaacg gagtttcaga
    12361 cagtttctta tcagtgagac tcagagttct atcgttctga ttggtgataa gatcatggtg
    12421 agcagaaaga gatggatggt aagaaatgtg gatttgatca tcgaaagagt ctgtgatggt
    12481 gagcgcgtgt tggtggagag taatttctag gttttcgact tccttgccaa aggttagctt
    12541 ttccgtacgg ctatcataga taggttcttt ggacatggaa agtaggcttt taatcccgtc
    12601 agattggata cctacaaaaa gaaggataaa gccgataacg gtagtcacca caccaaagat
    12661 gagaaatcct tttgtccatt tacgcatgct ggttacctct ctttcttttt ttaagaacaa
    12721 attgtaccag gcgaacaatg agtagaccga agaagcgagc tacataggaa atgcctagta
    12781 aaactagcga agaagcaccg atagccagta aaccagaacc aaaaatcaag ataaaggctg
    12841 atttggcttg ggcgaggaca gtgaaacttt caactaaaaa taggaatccg ccgatgatac
    12901 ccagtatgga aactgcaaag aaagccagaa tgacagtcaa agcggctaca aggattgcga
    12961 acagggtcac gaggatggcg attcccagag gaatgccgat aggtgctgca aggagggcta
    13021 acaaggcgat atgtaaaatt tgtcggttat ttttttgagc gggtgcttca ttgatttttt
    13081 tatcgagaag attggataga acttcgtggg ccgcttcttt gggagttccc aaactagcga
    13141 tgagttcttc ttctccttcg actccagcat cgtcaaagag ctctctgaaa tagtccatgg
    13201 cttcgatacg gtcagcttca ggtagtttct tgagatagag ttctagctga gtcaggtatt
    13261 cagttcttgt catggcggat actcccttct atgatgccat tgatggtgtc tgtatagagt
    13321 gcccattcat cttttagggt caagagctgc tctataccac cgtttgtcaa ggagtagtat
    13381 ttgcgcatgc gaccttggaa ctctctagaa taggttgtca gaaagctatt gccttccaat
    13441 tttttgagaa tgggatagag tgtggattct ttgatattag cgatcagctt aatggtttgg
    13501 ctaatctcat aaccataaga atcaccctgc tccagtacgg ccaagatgag aaattcaatc
    13561 aaggcagagg atgttggaaa gtacatggga aacctccttt tctaatgtgt aagattttta
    13621 tatataattt ttctacacat acattgtaca tctaaaagaa agccctgtca agagaaatgt
    13681 gtaaaatttt tatatataaa aaacttctag ctaaaactag aagtttaaag gatcttatcc
    13741 gctctgtcca ctgtaaagag ggccacagtc atcaggatat cgatgagcaa gagggcagct
    13801 acagctggta cccaagagtg gaataggtca aaactgtaac caaagagggt tggcccaaag
    13861 gctgctagga tatagcctcc tgtttgagat aggccggaca attgggctgt cttttcaggg
    13921 gcgcttgtct tgagtgaaaa gttgaccatg agataaggga agagggcgct ggttgcggtt
    13981 ccgatgagga gatggatggc aagccagtaa atgaaattat tgattgggaa aaagagcatg
    14041 gaaatgccga ccacaccagc tagtgaaacc agagtgagca tgagctgacg gttgcgagta
    14101 gataaactgg ttgtcaggct tgggatggtc attgaaaaag gaatgctaat cagagataag
    14161 atagaagtca gcaagccagc ttcgtgactg gatagacctg catggataga catggtaggt
    14221 aaccaggtca tggcggtgta aaagatcaag gattgaaaac ctgaaaagat aataattgcc
    14281 caaacctgtt tattacgcat gacctttatt tgactttttt gtttggtttg tggagctagt
    14341 ctatgattat agcggtgatt tgggagccag accaaaaaag ttgctagaca gagtaacgtg
    14401 aggaggataa gtcctttcca agaactggct tgtgtaatgg gcacagctag ataggaagcc
    14461 agagccgttg caatccccat agacgttaca tataaggtgg tcagaaaacc aattttcttt
    14521 ggttgattgg cttggataag actaggaagc aggacattga tgactgcgac acttgcccca
    14581 accatcaagg ttcctagata gagcaggggc agattgatta gtcgaataag tgagccgatg
    14641 gtcaagaaga agaggctgta ggtgaagaga tgctccaagc cgattttctg agccagtcgg
    14701 gtagaaaatg gtgaaaagag ggtaaacata aggagaggca ggctggtcaa gacaccaagc
    14761 gaactaactt ctacctccag accttgcgaa atatttccca aaataatggg taaaacagta
    14821 aaaggagttc gcaaggaaac accaatcagg ataatacctg gaacaaaaaa gagtgattgc
    14881 tttttcatat aatatctctt ctagctgatt ttaataacag cttattttaa ggctttttca
    14941 ctataatgtc aagtaaggtt tctggctttc aagataaaaa tggaaaagtc ttgaaaatta
    15001 tgatagaatg gtggaaggga aaattcagga gagtagtagt gactcaaaat gttgaaagtc
    15061 ttctcgtatc cattgtaatc agtgcataca atgaagaaaa atatctgcct ggtctaattg
    15121 aagacttaaa aaatcaaacc tatcctaaag agaatattga aattctattt ataaatgcta
    15181 tgtccacaga tgggaccaca gctatcattc agcaatttat aaaagaagat gcagagttta
    15241 actcaattag attgtataac aatcctaaga aaaatcaagc tagtggtttt aacctgggag
    15301 ttaagcattc tgtagggggc cttattttaa aaattgatgc tcattcaaaa gttactgaga
    15361 gttttgtaat gaacaatgtg gctgttattc aacaaggtga atttgtctgt ggagggccta
    15421 gaccgacgat tgtcaaagga aaaggaaaat gggcagagac cttgcatctt gttgaggaaa
    15481 atatgtttgg cagtagcatt gccaattatc gaaatagttc cgaggataga tatgtttctt
    15541 ctatttttca tgggatgtat aaacgagagg ttttccagaa ggttggttta gtaaatgagc
    15601 aacttggccg aactgaagat aatgatattc attatagaat tcgagaacat ggttataaaa
    15661 tccgctatag cccaagtatt ctatcttatc agtatattcg accaacattc aagaaaatgc
    15721 tgcatcaaaa gtattcaaat ggtttgtgga ttggcttgac aagtcatgtt cagtttaagt
    15781 gtttatcatt atttcattat gttccttgtt tatttgtttt gagtcttgtg tttagtctag
    15841 cattgttacc gatcacattc gtattcataa ctttactatt aggtgcctat tttctacttt
    15901 tatcattact gtcattactc actttgctga ctttattaaa acataaaaat ggatttctaa
    15961 ttgtgatgcc ctttctttta ttttccattc actttgctta tggccttggg acgattgtag
    16021 gtttaattag aggatttaaa tggaagaagg agtacaaggg aacagtaatt tatttggaaa
    16081 aataagccaa ataaattaaa atgtgctata ataacaatat agtagaacta ttttaaggag
    16141 gagtaaattt ctatgaataa aaaactcaca gattatgtga ttgatctggt ggaaatttta
    16201 aataaacaac aaaagcaggt tttctgggga atatttgata ttttcagtat ggtggtttcc
    16261 atcattgtat cttatatttt attttatggg ctgattaatc cagcacctgt tgactacatt
    16321 atctatacga gtttggcctt cctgttctat caattgatgg ttgatttttg gggcttgagc
    16381 gcgagtatta gtcgttacag caagattacg gatttcatga aaatcttttt tggtgtgact
    16441 gctagcagtg tcttgtcata tagtatctgt tatgccttct tgccactctt ctccatccgt
    16501 tttatcattc tctttatctt gttgagtgcc ttcttgattt tattgccacg gattacttgg
    16561 cagttaatct actccagacg caaaaaaggt agtggtgatg gagaacaccg tcggaccttc
    16621 ttgattggtg ccggtgatgg tggggctctc tttatggata gttaccaaca tccaaccagt
    16681 gaattagaac tggtcggtat tttggataag gattctaaga aaaagggtca aaaacttggt
    16741 ggtattcctg ttttgggctc ttatgacaat ctgcctgaat tagccaaacg ccatcaaatc
    16801 gagcgtgtca tcgttgcgat tccgtcgctg gatccgtcag aatatgagcg tatcttgcag
    16861 atgtgtaata agctgggtgt caaatgttac aagatgccta aggttgaaac tgttgttcag
    16921 ggccttcacc aagcaggtac tggcttccaa aaaattgata ttacggacct tttgggtcgt
    16981 caggaaatcc gtcttgacga atcgcgtctg ggtgcagaac tgacaggtaa gaccatctta
    17041 gtcacaggag ctggaggttc aatcggttct gaaatctgtc gtcaagttag tcgcttcaat
    17101 cctgaacgca ttgtcttgct cggtcatggg gaaaactcaa tctaccttgt ttatcatgaa
    17161 ttgattcgta agttccaagg gattgattat gtacctgtga ttgcggacat tcaagactat
    17221 gatcgtttgt tgcaagtctt tgagcagtac aaacctgcta ttgtttatca tgcggcagcc
    17281 cacaagcatg ttcctatgat ggagcgcaat ccaaaagaag ccttcaaaaa caatatccgt
    17341 ggaacttaca atgttgctag agccgttgat gaagccaagg tgcctaagat ggttatgatt
    17401 tcgacagata aggcagtcaa tccaccaaat gttatgggag caaccaagcg cgtggcggag
    17461 ttgattgtca ctggctttaa ccaacgtagc caatcaacct actgtgcagt tcgttttggg
    17521 aatgttcttg gtagccgtgg tagtgtcatt ccagtctttg aacgtcagat tgctgaaggt
    17581 gggcctgtaa cggtgacaga cttccgcatg acccgttact ttatgaccat tccagaagct
    17641 agccgtctgg ttatccatgc tggtgcttat gccaaagatg gggaagtctt tatccttgat
    17701 atgggcaaac cagtcaagat ttatgacttg gccaagaaga tggtgcttct aagtggccac
    17761 actgaaagtg aaattccaat cgttgaagtt ggaatccgcc caggtgaaaa actctacgaa
    17821 gaactcttgg tatcaaccga actcgttgat aatcaagtta tggataagat tttcgttggt
    17881 aaggttaatg tcatgccttt agaatccatc aatcaaaaga ttggagagtt ccgcactctc
    17941 agtggagatg agttgaagca agctattatc gcctttgcta atcaaacaac ccacattgaa
    18001 taaaaaagaa aaacgcatat tatcaagtta aataaccttg gtaatatgcg ttttattatg
    18061 tagagactta tactcttcga aaatctcttc aaatcacgtc aacgtcgcct tgccgtatat
    18121 ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca gtgttttgag ctgacttcgt
    18181 cagttccatc tacaacctta aaacagtgtt ttgagcagcc cgcagctagt ttcctagttt
    18241 gctctttgat tttcattgag tattacttca ttttcttctg aaatagagtt gtcgcccagt
    18301 ctatgctatt gaaaatacgc caaaacttct aagggtttgt gagcgatata atcaggttga
    18361 tagtttagta gatctgcttg ctctccaaat ccccaagtga cggccaattt ctgaatacct
    18421 gtttctcgag ctcccagcat atcaaacttg gtatctccga tgatgatggc ttgttctggt
    18481 gctagttgat gtgtctgtaa ggcttggtga atgacatctg ccttatgggg tgcttcaggg
    18541 ctagaaccat aaataccatc aaagaaatga tggatttcca agtttttggc catgtcttga
    18601 gcagtagatg tattctttgt cgtggtgatg tagagtggat aactgctcga taactcctca
    18661 agcaagtcta taatctgagg aaagagttga gcttcataga tgccttttgc cttatagtaa
    18721 gaacgatata tctgcatggc ttcagaaatt tggtctttgg acaggcaggt cgcaaaacta
    18781 ctttcgagag gtggtcccat aaaaccacga atagttttgg catcagggct aggcaccccc
    18841 agctctttaa aagtataggt aaaggcattg tgaatcccga tagaactatc aacgagggtt
    18901 ccatccaaat cgaaaaaaat cgctgtgata gaggtcatgg tttctcctat ttgataagct
    18961 tattctccga aaatctcttt ttggaggcga cgaccagtag gggtggtagc gagtccacct
    19021 tcagctgttt cacgaaaggc agttggcatg cttgctccta cttggtacat ggcatcgatc
    19081 acttcatcca cagggatttt agattcgata cctgccaagg ccatgtctgc tgcgatgaaa
    19141 gcaaagctag ctcccatggc attacgtttg acacagggaa cttcgaccaa acctgcaaca
    19201 gggtcacaga tgaggcctag catattttta atgacaaagg caatagcttg actggcctga
    19261 taaggtgttc cacctgcagc cagagtcaag gcggcagcac tcatagcaga ggctgaacca
    19321 acttcagctt gacacccacc ctcagcacct gagatggagg cattgtttgc gatgactagt
    19381 ccaaaggcac cagcagcaaa gaggaaatcc aattgttgct cgtggctgag gtctaatttt
    19441 tcaatagcag cagtgagaac ggaagggaga caaccggcac ttcctgcggt aggagtagcg
    19501 cagaccaagc ccattttagc attgtgttca ttgactgcga tagcatttcg ggcagcagag
    19561 agaatcgtgt aatctgataa agttttttcg tttttgatgt agtgatccaa tttggcagca
    19621 tctccacctg tcaggccact acgagattta ttttcattga ggccaagttg gacagaggct
    19681 ttcataactt ccagattgcg ttccatgaga aggaagactt cttcacgttc gcgaccggtc
    19741 aattcaaact ctgttgtaat catgagttct gcgacatttc cttgaaagtc cagatctgct
    19801 tgctcgacca attctttgat agaataaaac atgcttcctc ctatttaaag aaattgacat
    19861 tgtggagatg agggattttt cgaatttctt cgatagcctc atcacagttg cgactgtcaa
    19921 cttcgataat cataatggct ttttcaccag ctttttcacg agtgacattc atctgggcga
    19981 tattgatacc atagcgggaa agcgcctctg taacaagggc aatcatacct ggaatatctt
    20041 gatgaacgat gatgatagtc ggtgtattca tattgagaga gacggcaaaa ccattgagtt
    20101 cggttacctg aatatttcct ccaccgatag aaataccagt cacgctgatg gtcttgtggg
    20161 catttttaac agtaatttta gtggtgttag ggtgaggggc attgctgtct ttctgaatgg
    20221 tccagacaat cttgatacca cgcttgtggg caatttccag actatttgga atttcaggat
    20281 catctgtatc cattcctaaa atacctgcaa caagggctag gtctgttccg tgaccacgat
    20341 aggtcttggc aaatgagtta aaaagttgga attcaacttc tgtcggagta tcatcaaaaa
    20401 tggaagagac aatcttccca atacgaacag caccagcggt atggctacta gatgggccaa
    20461 tcataactgg tccgatgata tcaaagacag attgaaaacg aagtgatttc atcagtttcc
    20521 ccttataaaa attcttatct ctattatatc aaagaatgag gggcttggct ttaattgtgg
    20581 atgaaaacct ttctaatacc tcaaatagca taaaaatagt atcttttatg acaaaaaaca
    20641 ccttatttag ggaaataaaa aataattttg taatatttct acataaaagt gtcaagaaac
    20701 ggtaatattt aaagggtatg atagaactat agaaagaagg agaattttcg aatatgaaat
    20761 caataactaa aaagattaaa gcaactcttg caggagtagc tgccttgttt gcagtatttt
    20821 ctccatcatt tgtatctgct caagaatcat caacttacac tgttaaagaa ggtgatacac
    20881 tttcagaaat cgctgaaact cacaacacaa cagttgaaaa attggcagaa aacaaccaca
    20941 ttgataacat tcatttgatt tatgttgatc aagagttggt tatcgatggc cctgtagcgc
    21001 ctgttgcaac accagcgcca gctacttatg cggcaccagc cgctcaagat gaaactgttt
    21061 cagctccagt agtaagtgaa acagttgttt caactgtaag cggatctgaa gcagaagcca
    21121 aagaatggat cgctcaaaaa gaatcaggtg gtagctatac agctacaaat ggacgttata
    21181 tcggacgtta ccaattaaca gattcatacc tgaacggtga ctactcagct gaaaaccaag
    21241 aacgtgtagc agatgcctac gttgcaggac gttacggttc atggactgct gctaaaaact
    21301 tctggcttaa caatggctgg tattaagaac taacgaacaa ataatatgta aagagtcgag
    21361 gaaatccctc ggctttttta tctttccttc gcttggtaat agatctctac ttcttttttg
    21421 agatgagaca gcatagaagt ttcctcggtt agctccagaa gggagaaccc tttttggata
    21481 agtttagaat cgtctgtaca aatcccaata cggacatagc agatagccag cctatcgtag
    21541 cttttcttat tcttggcgtc ctctagtaaa gtgtagcaga tttgcttaca catgttttta
    21601 tcttgattgt atagatagag tgtggaaagg ttgagcagga ttgctatttg caagtcatat
    21661 aaatgttgat agtttttata gacttctaag cgttgcaaga ttttctcgga ttattgacaa
    21721 ataaacggac attctgatag acgattgccc tagcggctta gtgtaaactt tacaaatttg
    21781 gcttgtaatt tttttataaa attcacttca gttacttgac agttattata ttttcactta
    21841 ttatatagat aaaaggatga gatgggagtt taaaaatttg aaagcgctat ccatattgtt
    21901 tattggactg attcttgagt aatagttaga gtgtgcttaa tactactctg gttgttcaag
    21961 gacctgatac agaagcgcac cattctctcg gttaagagta agttcgttgt taaaaaatga
    22021 aatgagatag aaggaaggtg agtccaatgg actacgatac ttgttgataa attactatag
    22081 ctgtttttac ggaagagctc tcgataatag gagaaataaa tcatgagaaa attagttaaa
    22141 attggtgttg catctttaat ggtatgtagt atacttgctt ctacaagtgt tttggcagta
    22201 tgggttgatg gtggtcaatg gaactatgga gtaggatggt caggaaattt tggttattct
    22261 gattatttac attctactcg ctctcataca gcaactgtta aagatggaaa taaattctct
    22321 aaggatcgtg cagaagctga ggcatgggct cgggcttcaa tcttcaaatt cccaccaacg
    22381 ggaatggaat atttctatgg attttaatta aaattctccc tccccttttg gagagggagt
    22441 ttcttcacgg gaggtatctc tatgaaaaaa atcagtcatc tttgtatgtt actcctgctt
    22501 ctgtgtacca ctttttttgt ttttaatgta aactatacac gagaagtggt tcggattcaa
    22561 gaaatgggaa agactgtaga ttctttggat ttgtatttga aagatattaa cgaacctgca
    22621 gcgtctgttc ttcgattttt tgaggatgta tcaaaggagt ataaagtctc catcatcaaa
    22681 acagacagtg gtgatgaggt ggtcaagtct ggtgtttttg ataaagatac cttcccctac
    22741 caagagtttg ggatttcttc tcttgatttt accacagatg gtgaaggagt ctatagtaat
    22801 aaagaaattt ccaataaact tggtacgatt ccgacctttc taaaagccaa acctattcag
    22861 cttatgactt ttcaaaccta tatcaaggat acatctcgta gtttaaatgg tcgctatacg
    22921 ataacttcta cacaagagat ggacaaggat aggattgtac agaaatggag cgattttttc
    22981 aagatagacc aggctacctt gctagagccg acctacaaaa gtgcagtgga agtcataaat
    23041 cgagatttgc ttttatctgc cattgttttt gtcttggcta ttttgcttct tgtgttagtg
    23101 acagtgtatc aaccgatgat ggagatgaaa agagttgggg tacaaaaatt acttggtttt
    23161 caagataggg ctgttttagc tgatgttgta aaaggcaacc tttacctcct cctaggtggg
    23221 gctcttgtga tcaatctagg cgtgtttttc ttgcttgatt ataagccaaa agatttgttt
    23281 cctatgctgt ggttgtctca ttttttgctg ttgcagcttt atctctttat cagttggttg
    23341 acttacctct taatccaaaa aatgacaatc agctctctgc tgaaaggttt ttcatctttc
    23401 aaatttggtc tactctttaa ttatttgatg aaaattggaa ctaccatttt actgacagtc
    23461 ttgctagttg gggtaggaaa aagtttggag caagaaaaca aagagttgga ttaccagaaa
    23521 cagtggatca gccaaggaaa ttatctgacc ttagaaactt tccaactcaa tgataacttg
    23581 tggcaagagc agttggcagg ctcagggaag gcattggatt atttctatcg attttatcag
    23641 gatttggtag aaaaaacgca ggcgggctat gtgcagagta gcagtcttcc tgtaaaaaat
    23701 tttgtccaat cagaacagat tcagcaatat cagttaacag atacggtgga tgtttactat
    23761 gccaatcgca attttctaaa gagcaaggga ttcaagctac cagataccgg tattaaaaaa
    23821 gttattttga tgccagcaag tacgaaaggt gaagaagata aaaatcagct cttggggaag
    23881 ttaattgcct ttcattcgat gaagtatgaa gagcagcaaa aacgaacgat agaggagatg
    23941 gatgtcgaga ttgcctatta tgaaggagat tggtcatttt tcccatatag tgataagcga
    24001 aaggaaaatc tctccaatcc aattattagc ttggtcaatg attctgatat gatgtgggat
    24061 gagaaagcct ccctgtcaac aactggctta aataatccga ttaaaattga aaatacggtt
    24121 caacatcaaa aagagattac agagttagtt gagaaattgt cagatggaaa ttatttaaaa
    24181 ttttcatcta ttcaagccat tcaacaagag aaagtggatt cttatcgaga tgctgttcgg
    24241 aattttaacc tactctttgc tttgtttggt ctccttagca tgatgatttc ctacttctta
    24301 ctagtaataa ctttcttatt gaagcgcagg gatatcatta ccaagaagtt tatggggtgg
    24361 aaactggtcg atcgctaccg tcctctcctc gttctgctct tgctgggcta tagtttccct
    24421 cttctagtct tgattttctt tgcccatgcg ttcttgccac ttctgctgtt tgcaggcttt
    24481 acatgtttgg atatactatt tgtgctagtc ttggcttcta ggatggagaa aagaagtcta
    24541 gtagagttat tgaaaggggg catcttatga ttgagttgga aaatattacc aaaaccattg
    24601 ggggaaaagt gattttggat cacttgtctc tcaggattga tcagggggat ttggtagcta
    24661 ttgttggaaa aagtggtagt gggaagtcga ccttgttaaa tttattaggt ttgatagatg
    24721 gtgattatag tggacggtat gagatttttg gtcagacaaa tctagcggtc aattctgcta
    24781 agtcgcaaac aataatccgt gaacatatct cttatctgtt tcaaaatttt gccctgattg
    24841 atgatgaaac ggtcgagtac aatctcatgc tggcgctgaa atatgtgaaa ttgtctaaga
    24901 aagacaagct caaaaaggtg gaagagattt tagagagagt aggtttgtca tctactttgc
    24961 atcaaaaggt ttccgagttg tctggtggcg aacaacaacg aattgcagtt gctagagcca
    25021 tcttaaaacc cagccagctg attttagccg atgaaccaac aggttcgcta gatcctgaaa
    25081 atagagattt ggtcttgaag tttctcttag agatgaatcg cgaggggaaa acagtcatta
    25141 ttgtgaccca cgatgcttat gtagcccaac aatgtcatcg gatcattgaa ttgggcgagg
    25201 ggaaatgagt ttgttcagct ctttttgact gactgaatac tcatgttttt cagagaggaa
    25261 tagcataaat acgcctagaa atgacatttt tatgtagtat ttctaggttt ttttgtttca
    25321 aattgaaaat ttttccaatt taggcttgac aaaggatgaa gataggtgta ttatttatac
    25381 aaccaaaaag aataaacata aaggagactt tgttatgaat aagatgaaga aggtgttgat
    25441 gacgatgttt ggtttagtga tgctccccct actatttgct tgtagcaaca atcaatcggc
    25501 tggaattgaa gccatcaagt ccaaaggaaa attggttgta gccctcaatc cagattttgc
    25561 tccatttgaa taccaaaaag tggttgatgg gaaaaatcag attgtgggtt cagatatcga
    25621 attagccaag gctatcgcaa cagaactagg tgtcgaattg gaactatctc ccatgagttt
    25681 tgataatgta ctggctagtg ttcaatcagg aaaagccgac cttgccatat caggtgtttc
    25741 taagacagat gaacggagca aggtgtttga cttttccatt ccctactata ctgcaaaaaa
    25801 taaactcatt gtcaaaaaat ctgacttgac tacttatcag tctgtaaacg acttggcgca
    25861 gaaaaaggtt ggagcgcaga aaggttcgat tcaagagacg atggcgaaag atttgctaca
    25921 aaattcttcc ctcgtatctc tgcctaaaaa tgggaattta atcacagatt taaaatcagg
    25981 acaagtggat gccgttatct ttgaagaacc tgtttccaag ggatttgtgg aaaataatcc
    26041 tgatttagca atcgcagacc tcaattttga aaaagagcaa gatgattcct acgcggtagc
    26101 catgaaaaaa gatagcaagg aattgaaaga ggcagtcgat aaaaccattc aaaagttgaa
    26161 ggagtctggg gaattagaca aactcattga ggatgccttt aaagcatcca ttgaaaaata
    26221 gaaagaagga aaagaacatg agtaaagaaa aagtaatttt ggcctattct ggcggtttgg
    26281 acacatcagt tgctattacc tggttaaaga aagactatga tgttgtttca gtttgtatgg
    26341 atgtgggtga agggaaagac ttagacttca tccatgataa ggctctcaag gttggggcag
    26401 tcgaatctta tgtcattgat gtcaaggacg aatttgctac agattatgtg ctagtggctc
    26461 ttcagtcaca tgcctattat gaacaaaagt accccttggt atctgccttg agccgccctc
    26521 ttatttctaa aaaattagtt gaaatagcgc atcagacagg agcgactaca attgctcatg
    26581 gctgtaccgg taaggggaat gaccaagtcg aataccagat tgcagtcgct aagaaagcga
    26641 atgaagctaa aaagtgatgg agtgatgggt tcagaataag aggttggtcg attggtagcc
    26701 tctttcttgt cgttgaaaaa gtgagatata ttgacttttg aaaaaaatgt cataattgag
    26761 ttgggataaa cgtaaaagtc atactttctc gttaaatcgt tcggcgattc atggtgacat
    26821 ggacacatag tagtaaacac actatgtggc ttggcagagc taaaaacttc tggcttaaca
    26881 atggctggta ttaagaacta acgaacaaat aatatgtaaa gagtcgagga aatccctcga
    26941 ctttttttat aatttctttg gttgataatg ggtctctact tcttttttga gatgagacag
    27001 catagaagtt tcctcggtca gctctaggag tgagaaccct ttttggataa gtttagaatc
    27061 gtctgtacaa atcccaatac ggacatagca gatagccagc ctatcgtagc ttttcttatt
    27121 cttggcgtcc tctagtaaag tgtagcagat ttgcttacac atgtttttat cttgattgta
    27181 tagatagagt gtggaaaggt tgagcaggat tgctattcgc aagtcatata aatgttgata
    27241 gtttttatag acttctaagc gttgcaagat tttctcggat tattgacaaa taaacggaca
    27301 ttctgataga cgattgccct agcggcttag tgtaaacttt acaaatttgg cttgtaattt
    27361 ttttataaaa ttcacttcag atacttgaca gttattatat tttcgcttat gcttattata
    27421 tagataaaag gacgggatag gagtttaaaa atttgaaagc gctatccata ataataacgc
    27481 ataattttct ccttttcgtg aaaaaagtta acgtaatttt aaaatgagct taataagagg
    27541 tactatgtag gtagaaaata aagataggag aaaaagtatg aataaaaaaa tattttgtat
    27601 tctggtatgt attatatcat tgattagtct agctataatc tttccatggg gctggtcgat
    27661 ataatgtaag ggagcttgag ttgttagtgg aggataaaat gttaagagta atagtagtta
    27721 ttcaatcttt agtaataata ctgcttgctg ttgctttatt attatctcgg aaaaactttg
    27781 attcgttaaa tgttgttctt ataatgatga tcgtatcaca attgttgtta ttagtatatt
    27841 tgataaaatc agggaatcag tgattagctg ttatttgaat taagtaaact gttaagcttc
    27901 aagcagtaac tggttttaaa tatttaaaat aagataaagg aaggaagtct aatttaggta
    27961 actaaacaaa gcctgcgatc acttgttagg aaactatcct aaccatgctt aataaaaaag
    28021 gagaaaataa atggaactcg tattaccaaa taattatgtt gctcttgagc aagaagagat
    28081 gatgtatctt gatgggggtg gtgttggtcg taactggtgg aatagtagag gtagttttgc
    28141 aacagttttg gatgtaggtt tggccatcta tagtggtggt gcaacaattt attctgctta
    28201 tgcgataaaa aaagctatct cagctaatag aggggctatt acgagaacat tacgtagttt
    28261 aataattaaa catgtaggta gtgcagctgg ccatttagtc aatactgcac taaacgttgc
    28321 actaactgtt actggatttt cactaggtgg agcaatcgca tatggggctg attgggctga
    28381 cggtagctta gatggttata tttttgctta aaatgaaaca tttttttgca ggaattggtg
    28441 aaattcattt tttgttattt ttattatatc taagcatgtc tgctagtcca attattggac
    28501 tagtgattgg atatactaaa ataaatctaa taaattctat tattatagct cttggtatga
    28561 tattggcatt aattttggta ttatcaagag tgtatagaaa atatttttat agagacgatg
    28621 atgactaaag tttttatcaa taatttgggc tccttgtcaa ctgtagtggg ttgaagaaaa
    28681 gctaacgtct ggggaagggg ttaaagcttt gctttatcaa atattgactt acagagttgc
    28741 tctattgtat tgatgtattc ttagtaaata atatggtgtt ttgaatgaaa gatgatcaga
    28801 aatatttatt agcgggactt tattcgcttc tagttgcaat attttatttt ccattgattg
    28861 agtccaaggg gatttttgta agtatattga tggcggtttt acttttatat ttaatatact
    28921 tcattggaac agtcattcat attgtgataa ttaagtttat aagaaaaaaa tcttttaagt
    28981 atttggttct atatccattt acttatgatg ggagctggag atttcaacct ataaacttac
    29041 tctactttcc agaaatggtg agagatgtca ttccgattaa tttagttcaa gaatattgcc
    29101 aaggacaacc ttacgggctg ttaaaaaaga tgctgaaaag aattcgattg tcacgagaga
    29161 tagctttact cctggctacc attatcgtct atttttttac gcatagaatt ctacctcttt
    29221 cagtatttac gttcatgttt tcttacatat tgatatttgc acaatcttat ttgggtggta
    29281 atactgcttg gattggaaat agaagattaa taatagatga tgaatttgaa aaaatcttgc
    29341 tttcaaaaag ttatataaaa gaaatatcat ctgcacgata ctcggaatac ttgacatgtg
    29401 aatacaaaaa ccttacacca atcatattgt tagctatttt tgaaaattta cttgactcct
    29461 acttgcttca gaatcagagt gaggttgact tagatatttt ttataaagtt ttacctttgc
    29521 tttataaaga aaaatatact atgggattca attactttgt aagtttaaat tatttactat
    29581 ataaggttgg atttttggga atcatttacg ataatgaagc attaggagat ttgtcaaaac
    29641 aatatttaaa cagaaatatt tcggaattac aagatggttc tttcgagggc ggtatacaag
    29701 atgctgttgc ctctaaacaa atagtagtta taaatgaatt tatagcttgt ttaaattcca
    29761 gatgcatgcc atcccaatat gatagatttt tttataaaga tagaccttat attttttcca
    29821 gaaagagtcc tattaagagg tgaaaatttg ttacatttgg attaacaagt gtcctaggga
    29881 ttagaaataa ctctagtata gctagatatt tttgagtaac tagaaatatc attaggctac
    29941 ccatatgatt gccagaaaag atggctgatg aatcttattt atactgttgc agtaggcgtt
    30001 gtctaggata aataagctat cttgatgggg gagattggaa taattttagt agaaacatta
    30061 aaggattatg ggcaagtagc acaggattag gtgatgcaat gtgctaagtt ggcttggtgt
    30121 tagcagtagt attatttaac aatggaaagt agactaaatg aaaaataaac gttatttttt
    30181 tgacacaatt ttaatgattt tactacttat aagcacgata ttttgtgtca gcccagtatt
    30241 tataaaattg gacatcttag gaactccctc tcatgccatc ttaacctttg tattggcgat
    30301 accgttattc tatattttgt ctcaatgctt acatactttg ctattactag tttcctcaat
    30361 cttttgtaaa ttaagaccaa tttattttta ttttatattt gtgatcatta taggagctag
    30421 gaaatactat cgaattctct ttcaccaact aatgggattt agtccaggaa tagcagtgtt
    30481 ttataaggag agtcaaacaa ctaagaatct gtttaaattt tactacttct tgtactttac
    30541 aacactaatt tcatactatt ttttctttac ttttgtgtat gacaaaccgt tgcttttgcc
    30601 tcttattcca ttttctatta tcatagcatt agtacaaaaa ctttatagaa ttgagaatca
    30661 gcaattattt ctgttaaaat caaaggtact aacaatactg gaatctaaga agaattgtga
    30721 gtttaatctt caggattatc atgaaatttg gaaattgcaa tcaaaatctg agttgccatg
    30781 cgtggcttta tcttatatca gtttgatcaa gccatatctt tcagagagcg tgcgtgaaca
    30841 aattgattta ttagaagtta agcgatttaa aaaaataaat catccaatat cactttatgg
    30901 tatgttggat gttataaaat taaatctata tttacggcat tataatgaaa aaataaatat
    30961 gaatcaatgt taaagaaaat tttagaggta agaccagact ttgttttaat cgagcagaat
    31021 attgatgata gtttaaatag ctcgcaacca ttatctttat ctttagctat ttcagaaatc
    31081 caacttttgc ttgaagtgta tatagggatc aaacatgttt caattaggag ataaaactag
    31141 aataacattt gctattatag gggcaagttg catattagtc agtatgtatc ttatacctct
    31201 cattaacacg gataataaat tttgggaaat acttttattt ataataggtg tattgctaat
    31261 tggaattgcg ttactaagtc aaaaaaaata aattttgaaa tagtattagt gagttcgcaa
    31321 tcatttattg ctagtggttt agaactgtta agtttcaagc aataattggt tttaaacctt
    31381 aggtaaccta taaaaacaaa taaggtagag aaaggatatc ttatttaggt aactaagtac
    31441 tataaacaca gtcgacaatc acttgttagg aaaccatcct aactatgctt aataaaaaag
    31501 gagaaaataa atggaactcg tattaccaaa taattatgtt gctcttgagc aagaagagat
    31561 gatgtatttt gatgggggat tttctattcc gagatggcct gttgcaacag ccattaatat
    31621 agcttttaat gatgtcttag gtggaggagc aatcagtcta gttagaaatt atattcgtaa
    31681 ttatggtttg cggcgagtta caagcgcaat tgctggagca gctgcaagat atgttggggt
    31741 acgagttgca aatagagtag caggatttgc actgtctgct attaatggat ttgcagcttg
    31801 gatgtcaatt ggcaatgcta ttacaacaat ctgggccaat aatgatgtaa ataggagaga
    31861 cccaaattta aacgccttgt ggtaactaga tatgggtatt aaaatggaaa aaatttttgt
    31921 tattattttt tttgtatgtc tatttatatc atccataact tttttagcct atgattttgt
    31981 tagcgaagaa ataaaaaagt tgattatttg gatgaatgtc gtttttttga ttttaatcat
    32041 agcaatgata atttatccaa aattaagaaa atgataagga cactgtaaaa ttatgatacg
    32101 taaactaatc atttttttat taatgctccc tctttttgtc ttgtggctag agttgcatgt
    32161 cctagtgaat aacttactat tgaatctaga atctcccctt gattttgtga ttagtatgag
    32221 tcttgctttc tgtagtttga ttttatcaaa aatagtttta gacatactat acgcattgaa
    32281 agatttgtac aagaaagaag ctcttattac gatttttcct tttattttta taggcaggaa
    32341 gaaagtaaat gtgaggttct cgccctattt ttcattccat cgtaaaagtt tgtcgcctga
    32401 tgatttaaga tctaggatta tatggagttt tattcttgaa attgctatta tcctagtatt
    32461 tattttaaaa attccttttg caatcatcat gcttactaca atatttttct ggactataat
    32521 ggatatcaat catctcgttt ttaataagac ggaatttctt tttaatcaaa acaaatggca
    32581 aaaagaagat tcgtttgaaa gtgatttgac gaaaacgtta aaggataaga tacaaaaatc
    32641 agagctaagt tattctgact taatgtctct tcagctgtat gatgcgatga accaatccac
    32701 ctttttaacg gatagtgaac tttttgagga tattttgaaa aaaatcgaag attctcataa
    32761 cacccttctg tgtacaggtc ttgtcgagtt actgctgtat gaaatttcta ttagtaacaa
    32821 taacaactgg caagaaaagg ttgataaaat tagaatacag ctcatcagaa tcaatcaatt
    32881 agattttttc tattatacaa gttggttaag gcaaaatttt gatttctgta tgaatagaga
    32941 gtatcataaa atgaaatctc ggaaattatt actgagtaat aaaaagatag tttaagttcg
    33001 tcctatttgt aaaacaaatg aaacaatttc aactaaggag gagaaaacaa atggaacttg
    33061 tattaccaaa taattatgtt gtgattgatg aagaagaaat gatgtatctt gatggggaag
    33121 cttatttaag caagcgtgct tgtcaaggaa tttgcgcagc tttagctatg agttcaggaa
    33181 cttttatagc attagctgga gctgcagttt taaccaaaaa actaataaac tatattaagg
    33241 ttggaggtct tggaggctgg cttattggtg cagcagcagg tgtattggct acagcagcag
    33301 ggaaaatagc ttactatatt ggatatggtg ttcttaatag aggttgtgat attaacggga
    33361 acccttatcc ttgggatgga ttcatatctg cgacagtaaa atgagtaatg tagataagat
    33421 tcgaaaaata cacattatcg tatgttggat gtatatattt ttatcattca gggcgattat
    33481 aaatgacacg gagtattttt tgcttatttt tttagctttt atctactcaa tagtatcact
    33541 acctctatat tctgtgaaaa ataaaatagt atctatctgt ctagccataa attcgattct
    33601 gttaatgagt ttccccattt taatcaataa gtttttccca gaaagttttt tgacttatac
    33661 cgtattaata agtgttttta ttacagagtt gataattttt catttaattg ggaaagattt
    33721 tgatattaaa ttgactaacg aatataagaa aattagtcag tttagaagca aggtgtctca
    33781 atctccttgg ataaaatatt tagagatttc tagttttata ttaactatat ttccatctat
    33841 tctttatggt acagttgata atcatgtact gactcttatc tttttgataa aaatttgtgc
    33901 agataccacg ataaaatttt tattcatcag attatttgac acaagtactt taatgaagag
    33961 gagaatattt tttcttttcg cattggatgt tatagcttac ttatttttag gatatctttt
    34021 agtgattcaa aaagcaggct atttgttttc ggttttactt cttttttcta atttttcagt
    34081 tccatttatc aaagaaaagg aattcgaatt atttaaaaat agcaagtaat agaaacatag
    34141 gttaaatctt agaacggctt aaaatcagat atgataaagg gaaatagtct tatctaggta
    34201 actaagtgct acaaacacaa tcgaggatca cttgttagga ttacatttta atcatgctta
    34261 ataagaatgg agaattccta tggggattgt attactctga agtttcgaat accttagttc
    34321 tcgtgatttt gagctattct aggtttagaa tccttcagaa tgtaaaattt taagcagtca
    34381 aagacttaga atagcccgaa aacatttatt ttatagcaat tctaggctta gaattgctca
    34441 tatatatgta tttgagctgc tcgatagtta ggatagctct attctgagaa atctgagcta
    34501 tcaatgcttc agaatagtat tcgccaatgg tttttattga agaggtgatt gttttatgat
    34561 agtctaaaat aaaactgatt taatagagta aatggagaat cgttacatga aacatttttt
    34621 tgcaggaatt ggtgagataa aacttgttgg ctacttattg tatatatgtg taggactagc
    34681 tcctcttttt catatatatg tcataggttc ggaactgagt tttgtgaaaa tagtgttatc
    34741 tattttggga gttatatttg taagtatgtt aactattgct cgaatttatc ggacttttct
    34801 ataaagaata gtttggactt gaactgtatc taaaaacaga ggttggtcga ttatcagcct
    34861 ctttcttgtc gttgaaaaga gtgagatata ttgacttttg aaaaaagatg tcataattga
    34921 gttgggataa atctaaaaat aatatagtag attgaatctg gaatagtccg ttatgactgt
    34981 taaaatattt ctagaaatta atttgacttt cctaatcgat ttgttcatat cttgtttcaa
    35041 tctactatac tttctcgtta aaccgttcgg caattcatgg tgacatggac acatagtagt
    35101 aagcacacta tgtggcttgg cagatctaaa aactgttccc ttgcgataag cctaataagc
    35161 acaacatagg gagttagaga agccgactct aatcaaccac tttgggcagt agtgagaact
    35221 gccccgtgct ttttattttg agaaaatatg gagtttgtcg ttgaaattac ttgattgtat
    35281 tttggattat caagaaagat tcaatggaaa aacatgtcaa gtatcaacga attataagta
    35341 tttagagact ttcaaagtga atttttgctt gactgattta catcatttat ttgacttaca
    35401 caaaatcaca cgagattatg ctagtcaaac aaaacctgct attcaagctg gtgtttttat
    35461 tttagaagat tttagaaata tcctatgtac aatgatgtaa tcgaaaggat atctttatgt
    35521 gagtttatcg gcgatatctt ctatatctaa gctagcaagt tgttgcatcg tagctaagga
    35581 tttatctaaa aatactatga aattggacgt catatttttt gaggataaaa ataaaagatc
    35641 cgcagtttta ggtttacgaa gagacaaaag cggagtattt aaaccagtta ctctacattt
    35701 tacaagcgct aagaaatatg ctaaagttcg taaaacagat gtgaaagaaa tgaaatggct
    35761 ataaagattg tccgcaggct taagcttgcg ttttttgttg tttaacgaaa ttaaaaaaca
    35821 agctctctca tcggaaatgt ttttatagga atgaaggaag atgatgctat gtttaaaaag
    35881 agaatcgaaa agggcaaaag tagtgtcttt atctttttgg agtagaagct tatgatatag
    35941 aaatttgtaa taaaaatgta atataaaaca tttgacaaat atttacgggg ggagtatact
    36001 taatataagt atagtctaaa aatgactatc agaaaagagg taaatttaga tgaataagaa
    36061 aaaaatgatt ttaacaagtc tagccagcgt cgctatctta ggggctggtt ttgttgcgtc
    36121 tcagcctact gttgtaagag cagaagaagc ccccgtagct agtcagtcta aagctgaaaa
    36181 agactatgat gcagcgaaga gagacgctga gaatgcgaaa aaagctttag aagaagcaaa
    36241 acgtgcgcag aaaaaatatg aggatgatca gaagaaaact gaggagaaag cgaaaaaaga
    36301 gaaagaagct tctaaagagg aacaagctgc aaatctgaaa tatcaacaag agttggttaa
    36361 atatgctagt gaaaaagatt cagtaaaaaa agctaaaatt ctgaaagaag tggaggaagc
    36421 tgagaaagag cataagaaaa aacgagcaga atttgagaaa gttagatcag aggtaattcc
    36481 tagcgcggaa gagttaaaaa agactagaca aaaagcagaa gaggctaaag caaaagaagc
    36541 agaacttatt aaaaaagtag aagaagctga gaaaaaagtt actgaagcca aacaaaaatt
    36601 ggatgctgaa cgtgctaaag aagttgctct tcaagccaaa atcgctgagt tggaaaatga
    36661 agtttataga ctagaaacag aactcaaagg gattgatgaa tctgactcag aagattatgt
    36721 taaagaaggt ctccgtgctc ctcttcaatc tgaattggat gccaaacgaa ctaaactatc
    36781 aacacttgaa gagttgagtg ataagattga tgagttagac gctgaaattg caaaacttga
    36841 aaaaaatgta gaatatttca aaaaaaccga tgctgagcaa actgaacaat accttgctgc
    36901 agctgaaaaa gacttagctg ataaaaaagc tgaattggag aaaactgaag ctgaccttaa
    36961 gaaagcagtt aatgagccag aaaaaccagc tgaagaaact ccagctccag caccaaaacc
    37021 agagcaacca gctgaacaac caaaaccagc gccggctcct caaccagctc cagcaccaaa
    37081 accagaaaaa acagatgatc aacaagctga agaagactat gctcgtagat cagaagaaga
    37141 atataaccgc ttgccccaac agcaaccgcc aaaagcagaa aaaccagctc cagcaccaaa
    37201 accagagcaa ccagttcctg caccaaaaac aggctggaaa caagaaaacg gtatgtggta
    37261 cttctacaat actgatggtt caatggcgac agga
//
LOCUS       DAVBOG010000019        35462 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.019, whole genome shotgun sequence.
ACCESSION   DAVBOG010000019 DAVBOG010000000
VERSION     DAVBOG010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 35462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35462
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.019"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..139)
                     /locus_tag="VQ865_000991"
                     /pseudo
     CDS             complement(1..139)
                     /locus_tag="VQ865_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
     gene            125..610
                     /locus_tag="VQ865_000992"
     CDS             125..610
                     /locus_tag="VQ865_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001855144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HET3135340.1"
                     /translation="MAPTDKEDLIRTLELAPHVEGGYFRQTKKASDTINLAGKGRALY
                     TSIYFLLEETNPSHFHRLTADEIWYFHAESPLTVHMITADGHYEAVTLGLDISKGQQL
                     HYCVPKGTIWGSTVDKDDALVSCLVAPGFEFEDFELFERVDLLATYPEHKEMIERLTR
                     Y"
     gene            694..1401
                     /locus_tag="VQ865_000993"
     CDS             694..1401
                     /locus_tag="VQ865_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000166478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135341.1"
                     /translation="MTKQVLLVDDEEHILKLLDYHLSKEGFSTQLVTNGRKALALAET
                     EPFDFILLDIMLPQLDGIEVCKRLRAKGVKTPIMMVSAKSDEFDKVLALELGADDYLT
                     KPFSPRELLARVKAVLRRTKGKQEGDDSDNIADNSWLFGTLKVYPERHEVYKANKLLS
                     LTPKEFELLLYLMKHPNMTLTRERLLERIWGYDFGQETRLVDVHIGKLREKIEDNPKA
                     PQFIRTIRGYGYKFKEL"
     gene            1402..2733
                     /locus_tag="VQ865_000994"
     CDS             1402..2733
                     /locus_tag="VQ865_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HET3135342.1"
                     /translation="MKRYLQFWLVNLSVSLILIAGMALTWISKGIGLFLLALSLGLGG
                     YWLFCLWKWEVAFETLHQPLLTSSEYFLEKGQEDLKSLAQYVSGLKTKVSQQDQQYKD
                     LAETMEVLLSHLTMGTFLVSAQGQMLLSSRSLPHYFPDVDGDISSLDDLKRMDIRNLV
                     HQAFDQKTRLKQEVSGFHEGDLILEVTAVPVFSPTQSVEAVLVLLYDLTTIRTYEKLN
                     LAFVSNASHELRTPVTSIKGFAETIKGMSAEEEALKDDFLDIIYKESLRLEHIVEHLL
                     TLSKAQQMPIQWTTLSLAEFVQDLTQSLQPQLKKKDLQLKVQVPDDVTLVSDSQLLSQ
                     ILLNLLSNAIRYTEQGGKIEVKTQKVNEGIKISVSDTGIGISQLEQDRIFERFYRVNK
                     GRSRQTGGTGLGLAIVKELSQLLGGQVTVTSQLGRGSCFTIFLPNQSFAQD"
     gene            2900..3775
                     /locus_tag="VQ865_000995"
     CDS             2900..3775
                     /locus_tag="VQ865_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000669496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-binding protein"
                     /protein_id="HET3135343.1"
                     /translation="MKFKKILTLAAIGLSGFGLVACGNQSSTSKQSASGTIEVISREN
                     GSGTRGAFTEITGILKKDGDKKIDNTAKTAVIQNSTEGVLSAVQGNANAIGYISLGSL
                     TKSVKALEIDGVKASRDTVLDGEYPLQRPFNIVWSSNLSKLGQDFISFIHSKQGQQVV
                     TDNKFIEAKTETTEYTSQHLSGKLSVVGSTSVSSLMEKLAEAYKKENPEVTIDITSNG
                     SSAGITAVKEKTADIGMVSRELTPEEGKSLTHDAIALDGIAVVVNNDNKASQVSMAEL
                     ADVFSGKLTTWDKIK"
     gene            3893..4756
                     /gene="pstC"
                     /locus_tag="VQ865_000996"
     CDS             3893..4756
                     /gene="pstC"
                     /locus_tag="VQ865_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000595184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HET3135344.1"
                     /translation="MTKQAFKEAVFRAIFFMSATVAVVAILLICFFIFSNGLPFMANY
                     GFARFLLGSDWSPTNIPASYGILPMIVGSLLITLGAIVIGVPTGILTSVFMVYYCPKP
                     VYGFLKSAINLMAAIPSIVYGFFGLQLLVPWIRTFLGNGMSVLTASLLLGIMILPTII
                     SLSESAIRTVPKTYYSGSLALGASHERSIFSVILPAARSGILSAVILGIGRAVGETMA
                     VILVAGNQPIIPSGLFSGTRTLTTNIVLEMAYASGQHREALIATSAVLFFLILLINAY
                     FAYLKGKSSYE"
     gene            4749..5564
                     /gene="pstA"
                     /locus_tag="VQ865_000997"
     CDS             4749..5564
                     /gene="pstA"
                     /locus_tag="VQ865_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015057412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HET3135345.1"
                     /translation="MSKYLLKLLVYCFSALTFGSLFLIIGFILIKGLPHLSLSLFSWT
                     YTSENISLMPAIISTVILVFGALLLALPIGIFAGFYLVEYTKKDSLCVKIMRLASDTL
                     SGIPSIVFGLFGMLFFVVFLGFQYSLLSGILTSVIMVLPVIIRSTEEALLSVSDSMRQ
                     ASYGLGAGKLRTVFRIVLPVAMPGILAGVILAIGRIVGETAALMYTLGTSTNTPSSLM
                     SSGRSLALHMYMLSSEGLHVNEAYATGVILIITVLMINTLSSLLSRKLVKGAS"
     gene            5566..6318
                     /gene="pstB"
                     /locus_tag="VQ865_000998"
     CDS             5566..6318
                     /gene="pstB"
                     /locus_tag="VQ865_000998"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003101281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HET3135346.1"
                     /translation="MGTFSVRHLDLFYGDFQALKNISIQLPERQITALIGPSGCGKST
                     FLKTLNRMNDLVPSCHIEGQVLLDEQDIYSSKFNLNQLRKRVGMVFQQPNPFAMSIYD
                     NVAYGPRTHGIRDKKQLDALVEKSLKGAAIWEEVKDDLKKSAMSLSGGQQQRLCIARA
                     LAVEPDILLMDEPTSALDPISTLKIEDLIQQLKKDYTIIIVTHNMQQASRISDKTAFF
                     LTGEICEFGDTVDVFTNPKDQRTEDYISGRFG"
     gene            6333..6983
                     /gene="phoU"
                     /locus_tag="VQ865_000999"
     CDS             6333..6983
                     /gene="phoU"
                     /locus_tag="VQ865_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001245788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HET3135347.1"
                     /translation="MRNQFDLELHELEQSFLGLGQLVLETASKALLALASKDKEMAEL
                     IINKDHAINQGQSAIELTCARLLALQQPQVSDLRFVISIMSSCSDLERMGDHMAGIAK
                     AVLQLKENQLAPDEEQLHQMGKLSLSMLSDLLVAFPLHQASKAISIAQKDEQIDQYYY
                     ALSKEIIGLMKDQETSIPNGTQYLYIIGHLERFADYIANICERLVYLETGELVDLN"
     gene            7051..7476
                     /locus_tag="VQ865_001000"
     CDS             7051..7476
                     /locus_tag="VQ865_001000"
                     /inference="COORDINATES: protein motif:HMM:NF025080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3135348.1"
                     /translation="MTNLSSVDSEELFQFYRERGNAENFIKERKAGFFGDKTDSSTMI
                     KNEVRMMMGCLAYNLYLFLKQLAGDEVKALTIKRFRRLFLHIAGKYVSTARRHILKFS
                     SLYAYSKQFQALFDTICQINLILPVPYRARGQGKTCLTE"
     gene            complement(7650..8030)
                     /locus_tag="VQ865_001001"
     CDS             complement(7650..8030)
                     /locus_tag="VQ865_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3135349.1"
                     /translation="MREFGEKIKRLRLAKKISRSEFCGDESELSIRQLIRIENGESRP
                     TLTKLKYIAERLGVEDYKLMPSYIELDKEYLELKYFLMRTPTYEDETIAQKKESVLIR
                     FLKSIMIGYLRKKDLSSQIIHIWH"
     gene            8242..9258
                     /locus_tag="VQ865_001002"
     CDS             8242..9258
                     /locus_tag="VQ865_001002"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3135350.1"
                     /translation="MEKQTVAVLGPGSWGTALSQVLNDNGHEVRIWGNLPEQINEINT
                     YHTNKHYFKDVVLDENIIAYTDLAETLKDVDAILFVVPTKVTRLVAQQVAQTLDHKAI
                     IMHASKGLEPDSHKRLSTILEEEIPEQLRSDIVVVSGPSHAEETIVRDLTLITAASKD
                     LQTAQYVQELFSNHYFRLYTNTDVIGVETAGALKNIIAVGAGALHGLGFGDNAKAAII
                     ARGLAEITRLGVALGASPLTYSGLSGVGDLIVTGTSIHSRNWRAGDALGRGESLADIE
                     ANMGMVIEGISTTRAAYELAQELGVYMPITQAIYQVIYHGTNIKDAIYDIMNNEFKAE
                     NEWS"
     gene            9280..10179
                     /gene="galU"
                     /locus_tag="VQ865_001003"
     CDS             9280..10179
                     /gene="galU"
                     /locus_tag="VQ865_001003"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HET3135351.1"
                     /translation="MTSKVRKAVIPAAGLGTRFLPATKALAKEMLPIVDKPTIQFIVE
                     EALKSGIEDILVVTGKSKRSIEDHFDSNFELEYNLKEKGKTDLLKLVDETTGMRLHFI
                     RQTHPRGLGDAVLQAKAFVGNEPFVVMLGDDLMDITDEKAVPLTKQLMDDYERTHAST
                     IAVMPVPHDEVSAYGVIAPQGEGKDGLYSVETFVEKPAPEDAPSDLAIIGRYLLTPEI
                     FEILEKQAPGAGNEIQLTDAIDTLNKTQRVFAREFKGARYDVGDKFGFMKTSIDYALK
                     HPQVKDDLKNYLIQLGKELTEKE"
     gene            10597..11529
                     /locus_tag="VQ865_001004"
     CDS             10597..11529
                     /locus_tag="VQ865_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135352.1"
                     /translation="MENKFVEFIENNKKVIISSVAVGVVLVLGFGWYSYNQQQAEQQA
                     KIVQLEKDSKSDKEQVDKLFESFDASSDESISKLKELSETSLKTDAGKDYLNNKVKES
                     SKAIVDFHLQKGLAYDVKDSDDKFKDKATLENNVKEINKQIDFIKKVDETFKQKKLDE
                     TVKSLTDIADKFQKQIDVLKKEEEQKASDKAKEDKKKEESTSSQSSNSSSQASSSSFS
                     SYSGNSDYAPEQTYTADNSQSYSGSTGGDNSNYKAPAATDNGGNDGYILGHVTGADGS
                     QRDFYFNRSNGDVRDTSGNHVGNFGGGITDFRQR"
     gene            complement(11632..12309)
                     /locus_tag="VQ865_001005"
     CDS             complement(11632..12309)
                     /locus_tag="VQ865_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HET3135353.1"
                     /translation="MKEIFDRRYPVTSFFLLVTALVFLLMLVTAGGNFDRADTLFRFG
                     AMYGPAIRLFPEQVWRLLSAIFVHIGWEHFIVNMLSLYYLGRQVEEIFGSKQFFFLYL
                     LSGMMGNLFVFVFSPKSLAAGASTSLYGLFAAIIVLRYATRNPYIQQLGQSYLTLFVV
                     NIIGSVLIPGISLAGHIGGAVGGAFLAVIFPVRGEKRMYNTSQRLGAVVLFVGLAILL
                     FYKGMGL"
     gene            complement(12293..12832)
                     /locus_tag="VQ865_001006"
     CDS             complement(12293..12832)
                     /locus_tag="VQ865_001006"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HET3135354.1"
                     /translation="MKSELRKQVLHEMKAISQEQKQAIDQALTERLLHHPFYQEAKVI
                     ATYLSFSHEFQTRELIEQALKDGKKVLIPKTYPKGRMEFVVYDPQQLVKTAFALLEPQ
                     GDVEVVDASQIDLIHVPGLAFTTKGYRIGYGGGYYDRYLEHFSGRTLSTIYPCQIQDF
                     IPENHDIPVQEVLIDEGNL"
     gene            complement(12844..13974)
                     /locus_tag="VQ865_001007"
     CDS             complement(12844..13974)
                     /locus_tag="VQ865_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyldiaminopimelate deacetylase"
                     /protein_id="HET3135355.1"
                     /translation="MLDLIQTRRDLHQIPEIGLEEFKTQAYLLDVIEKLTTGKDFVQI
                     RTWRTGILVYLQGSQPERTIGWRTDIDGLPIVEQTGLPFASQHQGRMHACGHDFHMTI
                     ALGCLERALEEQPKNNLLFLFQPAEENEAGGMLMYEDGAFGDWLPNQFYGLHVRPDLK
                     VGQIATNTHTLFVGTCEVKIRFKGKGGHAAFPHEANDALVAASYFVTQVQSVVSRNVN
                     PIEGAVVTFGVFQAGTTNNVITETAFLHGTIRALTQDMSLLVQKRVKTVAEGVAAAFD
                     MEVEVELKQGGYLPVENNPALARELMDFFDEKDGIELIDIEPAMTGEDFGYLLSKVDG
                     VMFWLGIDSPYALHHPQMSPKEEVLAIGVAAVSSFLKKKAAE"
     gene            complement(14042..14740)
                     /gene="dapD"
                     /locus_tag="VQ865_001008"
     CDS             complement(14042..14740)
                     /gene="dapD"
                     /locus_tag="VQ865_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HET3135356.1"
                     /translation="MTATKMNAQEIIQFIANAEKKTSVKVTFEGQLATAVPSSVVKLG
                     NVLFGDWKDVAPLLEGLVENQDYVVEQDARNSAVPLLDKRAINARIEPGAIIRDQVEI
                     GDNAVIMMGSVINIGAEIGAGTMIDMGAILGGRAIVGKNSHVGAGAVLAGVIEPASAE
                     PVRVGDNVLIGANAVVIEGVQIGSGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDAQ
                     TQQKTALEDALRTL"
     gene            complement(14970..15881)
                     /locus_tag="VQ865_001009"
     CDS             complement(14970..15881)
                     /locus_tag="VQ865_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3135357.1"
                     /translation="MNQYQKKIVNGKIYSLLSGLIWGICGILGEYFFTHYQVSSGWIT
                     SMRLTLAGSIVLIWSAIQLKSQVLDIWRDKKNYLPFLAYAILGIFSVQYFFYLCVEYS
                     NATTATILQFISPVFILFYNRLVYQKRASKSAVFYVLVAMLGVCLMATKGDLSQLSMT
                     PLALITGLLSAMGVMFNVILPQPFAKRYGFVPTVGWGMILAGLFSNVLSPVYQLSFTL
                     DIWSILICLIIAFFGTAFAFFISMKAVSLVSPLVVAVISASEPLSSALLSVLFLGLVV
                     DWSLLLAIALIILPMIFLSIEEAKESR"
     gene            complement(15946..18411)
                     /locus_tag="VQ865_001010"
     CDS             complement(15946..18411)
                     /locus_tag="VQ865_001010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3135358.1"
                     /translation="MQNQLNELKRKMLEFFQQKQKNKKSARPGKKGSSTKKSKTLDKS
                     AIFPAILLSIKALFNLLFVLGFLGGMLGAGIALGYGVALFDKVRVPQTEELVNQVKDI
                     SSISEITYSDGTVIASIESDLLRTSISSEQISENLKKAIIATEDEHFKEHKGVVPKAV
                     IRATLGKFVGLGSSSGGSTLTQQLIKQQVVGDAPTLARKAAEIVDALALERAMNKDEI
                     LTTYLNVAPFGRNNKGQNIAGARQAAEGIFGVDASQLTVPQAAFLAGLPQSPITYSPY
                     ENTGELKSDEDLEIGLRRAKAVLYSMYRTGALSKDEYSQYKDYDLKQDFLPSGTVTGI
                     SRDYLYFTTLAEAQERMYDYLAQRDNVSAKELKNEATQKFYRDLAAKEIENGGYKITT
                     TIDQKIHSAMQSAVADYGYLLDDGTGRVEVGNVLMDNQTGAILGFVGGRNYQENQNNH
                     AFDTKRSPASTTKPLLAYGIAIDQGLMGSETILSNYPTNFANGNPIMYANSKGTGMMT
                     LGEALNYSWNIPAYWTYSLLRENGVDVKGYMEKMGYEIPEYGIESLPMGGGIEVTVAQ
                     HTNGYQTLANNGVYHQKHVISKIEAADGRVVYEYQDKPVQVYSKATATIMQGLLREVL
                     SSRVTTTFKSNLTSLNPTLANADWIGKTGTTNQDENMWLMLSTPRLTLGGWIGHDDNH
                     SLSRRAGYSNNSNYMAHLVNAIQQASPSIWGNERFALDPSVVKSEVLKSTGQKPGKVS
                     VEGKEVEVTGSTVTSYWANKSGAPATSYRFAIGGSDADYQNAWSSIVGSLPTPSSSSS
                     SSSSSSDSSNSSTTRPSSSRARR"
     gene            18553..19809
                     /locus_tag="VQ865_001011"
     CDS             18553..19809
                     /locus_tag="VQ865_001011"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HET3135359.1"
                     /translation="MHIFDELKERGLIFQTTDEEALRKALEEGQVSYYTGYDPTADSL
                     HLGHLVAILTSRRLQLAGHKPYALVGGATGLIGDPSFKDAERSLQTKDTVDGWVKSIQ
                     GQLSRFLDFENGENKAVMVNNYDWFGSISFIDFLRDIGKYFTVNYMMSKESVKKRIET
                     GISYTEFAYQIMQGYDFFVLNQDHNVTLQIGGSDQWGNMTAGTELLRRKADKTGHVIT
                     VPLITDATGKKFGKSEGNAVWLNPEKTSPYEMYQFWMNVMDADAVRFLKIFTFLSLDE
                     IEDIRKQFEAAPHERLAQKVLAREVVTLVHGEEAYKEALNITEQLFAGNIKNLSVKEL
                     KQGLRGVPNYQVQADENNNIVELLVSSGIVNSKRQAREDVQNGAIYVNGDRIQELDYV
                     LSDADKLENELTVIRRGKKKYFVLTY"
     gene            complement(19887..21950)
                     /locus_tag="VQ865_001012"
     CDS             complement(19887..21950)
                     /locus_tag="VQ865_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HET3135360.1"
                     /translation="MSFKVLHRGYQHIRLSSSFSLTLDIQDYLRSLARDEKGIESIQF
                     YMDQQHFTLRIKEGFSVLDNAEAFLKRIDKGKVSELMTLPIRREESAYSIVSGAAVKR
                     VLFRSFVPYPIRYIWTCYQALGYIREAYQTLARKELTMEVLDCSAILLSLFMNQSKTA
                     SNIMFMLDLGNHLDQWSLKKTATDLEQSLLAKESDVFLVQGDTVVSIKSSDVQIGDVL
                     ILSQGNEILFDGQVVSGLGMVNESSLTGESFPVEKRESDLVCANTVLETGELRIRVTD
                     NQMNSRILQLIELMKKSEENKKTKQRYFIKMADKVVKYNFLGSGLTYLLTGSFSKAIS
                     FLLVDFSCALKISTPVAYLTVIKEGLNREMVIKDGDVLEKYLEVDTFLFDKTGTITTS
                     YPIVEKVLPFGDYSEEDILRISACLEEHIYHPIANAIVKQAEIEGIEHEEMHGKLQYI
                     ASKGIKSHIDGQPVLIGNYVLMQDEQIHISSEQNALIEEYKSHYNLLFLAYQNELIGM
                     FCIHTPLRKEAKTALDKLKAQGKKLILATGDTLTRTEELVKDLPFDQVYTDLKPDGKF
                     ELVEKLQKAGHTILMVGDGLNDSAALTLSDIGVVMNESADISKQMSDILLLDNRLDFF
                     QELDSLSSSLQTLIKKNIQDTVVVNSSLIGFGLFNWLSPSNLSILHNLTTLRIVLRSL
                     SIKNR"
     gene            complement(21952..22230)
                     /locus_tag="VQ865_001013"
     CDS             complement(21952..22230)
                     /locus_tag="VQ865_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003075836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135361.1"
                     /translation="MLKEVLTVAKVAKKSSLFLGGVAFGTLGLKILASKEAKKGYSKA
                     LAKAYKLKDELDASVSVVKQHGDDVLQDAKYLYEQEKKEEQLDSLIGE"
     gene            22382..23230
                     /locus_tag="VQ865_001014"
     CDS             22382..23230
                     /locus_tag="VQ865_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HET3135362.1"
                     /translation="MNTNLKPKLQRFASATAFACPICQENLTLLETNFKCCNRHSFDL
                     AKFGYVNLAPQIKQSANYDKENFQNRQQILEAGFYQAILDAVSDLLASSKTTTTILDI
                     GCGEGFYSRKLQESHSEKTFYAFDISKDSVQIAAKSEPNWAVNWFVGDLARLPIKDAN
                     MDILLDIFSPANYGEFRRVLSKDGILIKVIPTENHLKEIRQRVQDQLTNKEYSNQDIK
                     EHFQEHFTILSSQTASLTKTITAEQLQALLSMTPLLFHVDQSKIDWSQLTEITIEAEI
                     LVGKAF"
     gene            23852..24424
                     /locus_tag="VQ865_001015"
     CDS             23852..24424
                     /locus_tag="VQ865_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135363.1"
                     /translation="MNKLMKFISVFLTSIVLIVSAIPSVSAVYASEQVSQIETNMELQ
                     PVTSLTEEQINTLANEIQSFHPDVSQQWIKEVINRQLQGDYTIPPTYSPFRAAWQGIT
                     VNQMGALLDTAIALALGGTTAGLANLIKVKGKHAAKSAIRSAISRYLGSWFVNDVALE
                     FAMNLLSPGTYLAQLWDKNDAIPNNGRINF"
     gene            complement(25468..27726)
                     /gene="glgP"
                     /locus_tag="VQ865_001016"
     CDS             complement(25468..27726)
                     /gene="glgP"
                     /locus_tag="VQ865_001016"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000950172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen/starch/alpha-glucan family
                     phosphorylase"
                     /protein_id="HET3135364.1"
                     /translation="MLSLQEFVQNRYNKTIAECSNEELYLALLNYSKLASSQKPVNTG
                     KKKVYYISAEFLIGKLLSNNLINLGLYDDVKKELAAAGKDLIEVEEVELEPSLGNGGL
                     GRLAACFIDSIATLGLNGDGVGLNYHFGLFQQVLKNNQQETIPNAWLTEQNWLVCSSR
                     SYQVPFADFTLTSTLYDIDVTGYETATKNRLRLFDLDSVDSSIIKDGINFDKTDIARN
                     LTLFLYPDDSDRQGELLRIFQQYFMVSNGAQLIIDEAIEKGSNLHDLADYAVVQINDT
                     HPSMVIPELIRLLTARGIELDEAISIVRSMTAYTNHTILAEALEKWPLEFLQEVVPHL
                     VPIIEELDRRVKAEYKDPAVQIIDESGRVHMAHMDIHYGYSVNGVAALHTEILKNSEL
                     KAFYDLYPEKFNNKTNGITFRRWLMHANPRLSHYLDEILGDGWHHEADELEKLLSYED
                     KAAVKEKLESIKAHNKRKLARHLKEHQGVEINSNSIFDIQIKRLHEYKRQQMNALYVI
                     HKYLDIKAGNIPARPITIFFGGKAAPAYTIAQDIIHLILCMSEVIANDPAVAPHLQVV
                     MVENYNVTAASFLIPACDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAE
                     LVGEENIYIFGEDSETVIDLYAKAAYKSSEFYAREAIKPLVDFIVSDAVLAAGNKERL
                     ERLYNELINKDWFMTLLDLEDYIKVKEQMLADYEDRDAWLDKVIVNISKAGFFSSDRT
                     IAQYNEDIWHLN"
     gene            complement(27752..29269)
                     /gene="malQ"
                     /locus_tag="VQ865_001017"
     CDS             complement(27752..29269)
                     /gene="malQ"
                     /locus_tag="VQ865_001017"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HET3135365.1"
                     /translation="MKKRQSGVLMHISSLPGAYGIGSFGQSAYDFVDFLVRTKQRYWQ
                     ILPLGATSYGDSPYQSFSAFAGNTHFIDLDILVEQGLLEASDLEGVDFGSDASEVDYA
                     KIYYARRPLLEKAVKRFFEVGYVKDFEKFAQDNQSWLELFAEYMAIKEHFDNLAWTEW
                     PDADARARKASALESYREQLADKLVYHRVTQYFFFQQWLKLKAYANDNHIEIVGDMPI
                     YVAEDSSDMWANPHLFKTDVNGKATCIAGCPPDEFSVTGQLWGNPIYDWEAMDKDGYK
                     WWIERLRESFKIYDIVRIDHFRGFESYWEIPAGSDTAAPGEWVKGPGYKLFAAVKEEL
                     GELNIIAEDLGFMTDEVIELRERTGFPGMKILQFAFNPEDESIDSPHLAPANSVMYTG
                     THDNNTVLGWYRNEIDDATREYMARYTNRKEYETVVHAMLRTVFSSVSFMAIATMQDL
                     LELDEAARMNFPSTLGGNWSWRMTEDQLTPAVEEGLLDLTTIYRRINENLVDLKK"
     gene            29819..31090
                     /locus_tag="VQ865_001018"
     CDS             29819..31090
                     /locus_tag="VQ865_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000095461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3135366.1"
                     /translation="MSSKFMKSTAVLGTVTLASLLLVACGSKTADKPADSGSSEVKEL
                     TVYVDEGYKSYIEEVAKAYEKEAGVKITLKTGDALGGLDKLSLDNQSGNVPDVMMAPY
                     DRVGSLGSDGQLSEVKLSDGAKTDDTTKSLVTAANGKVYGAPAVIESLVMYYNKDLVK
                     DAPKTFADLENLAKDSKYAFAGEDGKTTAFLADWTNFYYTYGLLAGNGAYVFGQNGKD
                     AKDIGLANDGSIAGINYAKSWYEKWPKGMQDTEGAGNLIQTQFQEGKTAAIIDGPWKA
                     QAFKDAKVNYGVATIPTLPNGKEYAAFGGGKAWVIPQAVKNLEASQKFVDFLVATEQQ
                     KVLYDKTNEIPANTEARSYAEGKNDELTTAVIKQFKNTQPLPNISQMSAVWDPAKNML
                     FDAVSGQKDAKTAANDAVTLIKETIKQKFGE"
     gene            31201..32493
                     /locus_tag="VQ865_001019"
     CDS             31201..32493
                     /locus_tag="VQ865_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000414940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3135367.1"
                     /translation="MEKQQPSKAALLSIIPGLGQIYNKQKAKGFIFLGVTIVFVLYFL
                     ALATPELSNLITLGDKPGRDNSLFMLIRGAFHLIFVIVYVLFYFSNIKDAHTIAKRIN
                     NGIPVPRTLKDMIKGIYENGFPYLLIIPSYVAMTFAIIFPVIVTLMIAFTNYDFQHLP
                     PNKLLDWVGLTNFTNIWSLSTFRSAFGSVLSWTIIWALAASTLQIVIGIFTAIIANQP
                     FIKGKRIFGVIFLLPWAVPAFITILTFSNMFNDSVGAINTQVLPILAKFLPFLDGALI
                     PWKTDPTWTKIALIMMQGWLGFPYIYVLTLGILQSIPNDLYEAAYIDGANAWQKFRNI
                     TFPMILAVAAPTLISQYTFNFNNFSIMYLFNGGGPGSVGGGAGSTDILISWIYRLTTG
                     TSPQYSMAAAVTLIISIIVISISMIAFKKLHAFDMEDV"
     gene            32495..33337
                     /locus_tag="VQ865_001020"
     CDS             32495..33337
                     /locus_tag="VQ865_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3135368.1"
                     /translation="MNNSIKLKRRLTQSLTYLYLIGLSIVIIYPLLITIMSAFKAGNV
                     SAFKLDTNIDLNFDNFKGLFTETLYGTWYLNTLIIALITMAVQTSIIVLAGYAYSRYN
                     FLARKQSLVFFLIIQMVPTMAALTAFFVMALMLNALNHNWFLIFLYVGGGIPMNAWLM
                     KGYFDTVPMSLDESAKLDGAGHFRRFWQIVLPLVRPMVAVQALWAFMGPFGDYILSSF
                     LLREKEYFTVAVGLQTFVNNAKNLKIAYFSAGAILIALPICILFFFLQKNFVSGLTSG
                     GDKG"
     gene            33590..34390
                     /locus_tag="VQ865_001021"
     CDS             33590..34390
                     /locus_tag="VQ865_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000938258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HET3135369.1"
                     /translation="MLPYPFSYFSSIWGFRKPLSKRFELNWFQLLFTSIFLISLSMVP
                     IAIQNSSQETYPLETFIDNVYEPLTNEVVQDLSEHATIVDGTLTYTGTASQTPSVVIG
                     PSQIKELPKDLQLHFDTNELVISKESKELTRISYRAIQTESFKSKDSLTQAISKDWYQ
                     QNRVYISLFLVLGASFLFGLNFFIVSLGASLLLYITKKSRLFSFRTFKECYHFILNCL
                     GLPTLITLILGLFGQNMTTLITVQNILFVLYLVTIFYKTHFRDPNYHK"
     gene            34400..35386
                     /locus_tag="VQ865_001022"
     CDS             34400..35386
                     /locus_tag="VQ865_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3135370.1"
                     /translation="MPVTIKDVAKAAGVSPSTVTRVIQNKSTISDETKKRVRKAMKEL
                     NYHPNLNARSLVSSYTQVIGLVLPDDSDAFYQNPFFPSVLRGISQVASENHYAIQIAT
                     GKDEKERLNAISQMVYGKRVDGLIFLYAQEEDPLVKLVAEEQFPFLILGKSLSPFIPL
                     VDNGNVQAGFDATEYFIKKGCKRIAFIGGSKKLFVTKDRLTGYEQALKHYKLTTDNNR
                     IYFADEFLEEKGYKFSKRLFKHDPQIDAIITTDSLLAEGVCNYIAKHQLDVPVLSFDS
                     VNPKLNLAAYVDINSLELGRVSLETILQIINDNKNNKQICYRQLIAHKIIEK"
BASE COUNT        10850 a         7484 c         6670 g        10458 t
ORIGIN      
        1 cgctaattct tcttttaggg cgattgattt gtacttccgt cgcatcaatc attaccgtgt
       61 cctcagaact gagaggagtt cttgaaatcg taaaaccact ttgaacaaga gttacttcaa
      121 cccattggct ccgacggata aagaagactt gataagaact ctagagttag ctccccatgt
      181 tgaaggtggc tattttagac aaacaaaaaa agcttcagac actataaacc ttgctggtaa
      241 gggaagggcg ctttatacca gtatttattt cttattagaa gaaacgaatc cttcacattt
      301 tcaccgattg acagcagatg aaatctggta ttttcatgca gaatccccac ttactgttca
      361 catgattaca gcagatggtc actacgaagc agtcacttta ggcctggaca tatccaaagg
      421 gcaacaactt cactactgtg ttcctaaggg cactatttgg ggatcaacag ttgataagga
      481 tgatgctctg gtttcttgtc ttgttgctcc tggttttgaa tttgaggatt ttgaattatt
      541 tgaaagggta gatctactgg cgacctatcc agagcacaag gagatgattg agcgtttgac
      601 cagatactag tctttataag caaatttaat ctgatttagc aatgttagga tttctgataa
      661 ttgtgttata atgttaccaa taggagataa tagatgacaa aacaagtctt attagtggat
      721 gatgaagaac acattctgaa attgcttgac taccatttaa gtaaggaagg cttttctact
      781 caattggtaa caaatggacg gaaggcctta gctttggcag aaacagaacc ctttgatttt
      841 atcttgcttg atatcatgtt accacaatta gatggcatag aagtttgtaa gcggctgaga
      901 gccaaaggcg tcaaaactcc aattatgatg gtttctgcga aaagtgatga atttgataag
      961 gttttggcct tggaattagg ggctgatgac tacctgacca agccttttag ccctagagaa
     1021 ttactggcgc gtgtcaaggc tgtcctcagg cgaactaaag gaaaacaaga aggagatgat
     1081 tcagataata tcgctgacaa ttcttggcta tttgggacct tgaaagtata ccctgagcgt
     1141 catgaagtct acaaggcgaa taagttactg agtttgaccc caaaagaatt tgaactcttg
     1201 ctctatctta tgaaacatcc caacatgaca ctgactagag agcgtctttt ggaacgtatc
     1261 tgggggtatg actttgggca ggaaacacgt ttggtggacg ttcatattgg taagttgagg
     1321 gaaaaaattg aagacaatcc taaagcccct caatttattc gaaccattcg gggttatggt
     1381 tataagttca aggagttata gatgaaacgc taccttcaat tttggctagt caatctaagt
     1441 gttagcctca ttctgattgc agggatggca ttaacttgga tcagtaaagg catcggtctc
     1501 tttcttctag ccctttcttt gggactaggt ggctactggc tcttttgcct ttggaaatgg
     1561 gaagttgctt ttgagacctt gcaccaacct ctcttgacca gtagtgaata ctttttagaa
     1621 aaagggcaag aagacttaaa gtctttggct cagtatgtgt ctggcctaaa aaccaaagtc
     1681 tcccaacagg atcagcaata caaggaccta gccgaaacaa tggaggttct tctgtcgcac
     1741 ctaaccatgg ggacgttttt agtttccgct caaggtcaga tgttattatc cagtcgctct
     1801 ctgcctcatt attttcccga tgtggacggc gacataagtt cacttgatga cctcaaacgg
     1861 atggatattc ggaatttagt tcaccaagcc tttgatcaaa aaacaaggtt aaaacaagaa
     1921 gtaagtgggt ttcatgaggg tgacttgatt ttagaagtga cagcagttcc cgtttttagc
     1981 cccacccaat ctgtggaagc tgtgctcgtc ttgctatatg atttaacaac gattagaact
     2041 tatgaaaagt taaatttagc ctttgtctca aatgcctccc atgaattgag gacaccagtt
     2101 acttcgatta agggctttgc tgaaaccatt aaggggatgt cagctgaaga agaagcgctc
     2161 aaggatgact ttctagacat tatttacaaa gaaagcttgc gtcttgagca tattgttgag
     2221 catcttctta ccttatctaa ggctcaacaa atgcctatac aatggacgac cctttctttg
     2281 gcagaatttg tacaggattt gactcaaagc ttgcaacctc agctcaagaa gaaggattta
     2341 cagctaaagg tgcaggtgcc agatgatgtc accctcgtat cagatagtca attactttcc
     2401 caaatcttac tcaatctttt atccaatgcc atccgttaca ctgaacaagg gggaaaaatt
     2461 gaggtcaaga cccaaaaggt gaacgaaggc attaagattt ctgtatcaga tacagggatt
     2521 ggtattagtc aattagagca ggatcgtatt tttgaacgtt tttaccgagt taataaaggt
     2581 cgaagcagac aaactggtgg cactggtctt ggccttgcca ttgtcaaaga actcagtcaa
     2641 ttattaggtg gccaagtcac ggtgacgagt cagcttggca gaggcagttg cttcacgatt
     2701 tttcttccta accaatcttt cgcacaggac taataatttt taaagctatt tttaggagca
     2761 gccatttttc aaaagtggct ttttttgatt ctttacacaa tctttacatg aatcagggat
     2821 aaacctttac aaagacttgt tagactataa atgtagtaag cctacacaag aaaaatacat
     2881 agagataaag gtgattatta tgaaattcaa aaaaatactt actcttgcag ccattggctt
     2941 atcaggattt gggcttgttg cctgtggcaa tcagtcatct acttccaaac agtcagcttc
     3001 aggaacgatt gaggtgattt cacgagaaaa tggctctggg acacggggtg ccttcacaga
     3061 aatcacaggg attctcaaaa aagacggtga taaaaaaatt gacaacactg ccaaaacagc
     3121 tgtgattcaa aatagtacag aaggtgttct ctcagcagtt caagggaatg ctaatgctat
     3181 cggctacatc tccttgggat ctttaacgaa atctgtcaag gctttagaga ttgatggtgt
     3241 caaggctagt cgagacacag ttttagatgg tgaataccct cttcaacgtc ccttcaacat
     3301 tgtttggtct tctaatcttt ccaagctagg tcaagatttt atcagcttta tccactccaa
     3361 acaaggtcaa caagtggtca cagataataa atttattgaa gctaaaactg aaaccacaga
     3421 atatacaagc caacacttat caggcaagtt gtctgttgta ggttccactt cagtatcttc
     3481 tttaatggaa aaattagcag aagcttataa aaaagaaaat ccagaagtta cgattgatat
     3541 tacctctaat gggtcttcag caggtattac cgctgttaag gagaaaaccg ctgatattgg
     3601 tatggtttct agggaattaa ctcctgaaga aggtaagagt ctcacccatg atgctattgc
     3661 tttagacggt attgctgttg tggtcaataa tgacaataag gcaagccaag tcagtatggc
     3721 tgaacttgca gacgttttta gtggcaaatt aaccacctgg gacaagatta aataaaatgt
     3781 ttgctccata aatctctaaa gagatgcaga cgtttcatcg tacaataaga taaagaaggc
     3841 aagtagggag gtgtcgtatc tcccttactt tcttcactag aaaggacaag atgtgacaaa
     3901 acaagccttc aaagaagcag tttttagggc aatttttttc atgagtgcaa cagtagctgt
     3961 tgtagctatt ttgctaatct gtttctttat ttttagtaat ggcttacctt tcatggctaa
     4021 ctacggcttt gcccgttttt tattaggcag tgattggtcg ccaacgaaca ttccggcaag
     4081 ctatggtatt ttaccaatga tcgttggttc cttattaatt accttaggag cgattgtgat
     4141 tggggtgcca acaggcatct tgacatcggt gtttatggtt tattattgtc caaagcccgt
     4201 ctatggcttc ttaaaatcag ctatcaactt gatggcagcc attccatcta ttgtttatgg
     4261 ttttttcggc ctacaattat tggtgccttg gattagaacc tttttaggaa atggcatgag
     4321 tgtcctaacc gcttcgttac tattaggaat aatgattttg ccaaccatta tcagtttgtc
     4381 agaatctgct atccgaacag ttcccaaaac gtattattct ggtagcttgg ctctaggagc
     4441 tagtcatgaa cggagtattt ttagtgtcat cttgccagct gcgagatctg gtattttatc
     4501 agcagttatt ttaggaatcg gtcgcgcagt aggtgaaacc atggcagtta ttttggtggc
     4561 aggcaaccag ccaattattc caagtggact cttttcagga accagaacct taacaaccaa
     4621 tattgttctg gaaatggctt acgcatcagg tcagcatagg gaagccctta ttgcaacctc
     4681 agcagttctc tttttcctta ttctcttgat taatgcctac tttgcctact tgaaaggaaa
     4741 atcatcttat gagtaaatac ctgctaaaac ttctcgttta ttgtttttca gctttaacct
     4801 ttggctctct ctttttaatc attggtttta tcctcatcaa aggcttacct catctaagtc
     4861 tatccctctt ttcttggact tatacttctg agaacatttc ccttatgcca gcgattattt
     4921 ccaccgttat tctggttttt ggtgctcttc ttttagcttt gcccataggg atttttgctg
     4981 gtttttatct tgtggaatat acaaaaaaag attccctttg tgttaaaatc atgcgattgg
     5041 cctcagatac cttgtctggg attccttcca ttgtttttgg tctgtttggc atgctcttct
     5101 ttgtagtctt cttaggtttt caatactctc tgttatcagg aatcttaacc tcagttatca
     5161 tggtgttgcc agtcattatt cgctcaacag aagaagccct tttatctgtt agtgatagca
     5221 tgcgtcaagc aagttatgga cttggggcag gtaagttacg gactgttttt agaattgttc
     5281 taccagttgc catgccaggt attttagctg gagtgatact agctattggc cgtatcgttg
     5341 gtgaaacagc tgccctcatg tatacattag gtacctctac caatacgcca agtagtctca
     5401 tgtcttcagg ccgttctcta gccctacata tgtatatgct gtcaagtgag gggctacatg
     5461 tcaatgaagc ctatgctacc ggcgtgattt taattattac tgttttaatg ataaatactc
     5521 tatcaagctt attatctcgg aaacttgtga aaggagcttc ctagtatggg aacattttca
     5581 gtcagacacc tagacttatt ttacggggat tttcaagcct taaaaaatat ttcgattcaa
     5641 ttaccagaaa gacagattac tgccttgata ggcccatctg gttgtggcaa atcaactttt
     5701 ctaaaaaccc ttaaccggat gaacgatttg gttccttctt gccatattga aggccaagtc
     5761 ctcttagatg agcaagatat ttatagtagc aaattcaacc ttaatcagct acgtaagcgt
     5821 gtagggatgg tttttcaaca gcctaatccc tttgccatgt ctatctatga taacgtggct
     5881 tatggcccaa ggacacatgg tattcgagac aaaaaacaat tagatgcctt agtggagaaa
     5941 tctttaaaag gggcagccat ttgggaagaa gtcaaagatg atcttaaaaa gagtgccatg
     6001 tccttatctg gcggtcagca gcaacgcctt tgcattgcgc gagctttagc agtagaacct
     6061 gatattctgt taatggatga gccgacttca gccttagacc ctatctccac tttaaaaatt
     6121 gaagacctca ttcagcaact aaaaaaagat tatacgatta tcattgttac ccataacatg
     6181 caacaagctt cacgtatttc agataaaact gcttttttct taacaggaga aatttgcgaa
     6241 tttggagata ccgttgacgt gtttaccaat ccaaaagatc agcgcacaga agactatatt
     6301 tcaggacggt tcggataagg aaggaaaaac ctatgagaaa tcaatttgac ttagaattgc
     6361 atgaattaga acaatccttt ttaggactag ggcaacttgt ccttgaaaca gcttcaaaag
     6421 ccttactggc cttagcctcc aaagacaagg agatggcaga gctaattatc aataaggatc
     6481 atgctatcaa ccaaggtcaa agcgctatcg aattgacctg tgcccgtttg ttggccttgc
     6541 agcagccaca agtgtctgac cttcgatttg tgattagcat catgtcttct tgttcagacc
     6601 ttgaacgtat gggagaccat atggcaggca ttgccaaagc tgttttgcaa ctaaaagaaa
     6661 atcaactagc ccctgacgaa gaacagttac accaaatggg taaattatcc ctcagcatgc
     6721 tatccgattt attggttgcc tttcctttgc accaagcctc aaaagctatt agtattgctc
     6781 aaaaagatga acagattgac caatattatt atgccttatc aaaggaaatc attggactta
     6841 tgaaagacca agaaacctca attcccaatg gaacacaata cctttatatc atagggcatc
     6901 tggaacgctt cgctgattac attgctaaca tttgtgaacg cctagtctac ctagaaacag
     6961 gagaactagt ggatttgaat taattcaact aatccttaaa agagaagagt acgattaagt
     7021 gctctttttt atggttgtaa aaaagttcat ttgaccaatt taagcagtgt agatagtgag
     7081 gagctgtttc aattctatcg tgaacgaggg aatgctgaaa actttatcaa agaaaggaaa
     7141 gcaggattct ttggggataa gacagatagt tcgaccatga ttaagaatga agtacgtatg
     7201 atgatgggct gtctggctta taatctctac ctctttttaa agcagctagc tggtgatgaa
     7261 gtaaaggcct tgactatcaa gcgttttcga cgtctcttcc ttcatattgc cggaaaatat
     7321 gtctctactg ctagacgaca tattctcaaa ttctcaagtc tatatgccta ttcaaaacag
     7381 tttcaagcct tatttgatac aatctgccag ataaatctga tactccctgt tccatataga
     7441 gctagagggc aggggaaaac atgcctaaca gaataagtca ccttatttta aaaatcgagc
     7501 atcaaaccaa gggaggagtc tgcccttttt taggaaaaaa tcaagacaaa tctcctcaat
     7561 tatgtctcta acatcagaaa ttaagcaaaa tcaccagaag gacagtattt caactagctt
     7621 ttctggtaat ttttgaactg tgtagttcgt tagtgccaga tatgaataat ttgggatgat
     7681 aaatctttct tcctcaggta gcctatcata atactcttca aaaatcttat caaaacactc
     7741 tctttctttt gggcgatagt ttcatcttcg tatgtaggag tcctcatcaa gaaatacttc
     7801 aattctaggt attccttatc caactctata taacttggca tcaacttgta atcctcaacc
     7861 cccaaacgtt cagcgatata ttttaacttt gttagtgttg gtctggattc tccattttca
     7921 attctaatta attgacggat acttaattca gactcatcac cacaaaattc tgaacgactg
     7981 atttttttag ccaaacgtaa tcttttaatt ttttcgccaa actctcgcaa cctacaagaa
     8041 cctcctgagt tgtttacctc tattataagc atatactgaa tcaaactatc tatcagattt
     8101 cttctcactt taactaaaga ctaagagttt atcccttcat ctcggtcttt gtgtattttt
     8161 ccaccatacc ccagtaatgc aagtgcaaaa tcctctagaa tatgatagaa taatggaaag
     8221 aactctatca aggaggaaat catggaaaaa caaaccgtcg ccgtcttggg gcctggttct
     8281 tggggaactg ccctttcaca agtcttaaat gacaatggac acgaggtacg tatttgggga
     8341 aatcttcccg agcaaatcaa tgaaattaat acctatcata ctaacaagca ctactttaaa
     8401 gatgtcgttc tagatgaaaa tatcattgcc tacaccgact tagcagaaac attgaaagat
     8461 gtggatgcga ttttgtttgt tgtcccaaca aaagtgacac gacttgttgc ccaacaagtt
     8521 gcacaaacct tggaccataa ggctatcatc atgcacgctt caaagggatt agaacctgat
     8581 agccataaac gattatcaac tatccttgaa gaagaaattc ctgaacagct ccgcagtgat
     8641 attgtcgttg tttcagggcc tagtcatgcg gaagaaacca ttgtgcgtga cctaacttta
     8701 atcactgctg cttctaaaga tttacaaaca gctcaatacg ttcaggagct atttagtaat
     8761 cactacttcc gactttatac caatacggat gttatcgggg ttgaaactgc tggtgctctt
     8821 aaaaatatta ttgctgtcgg tgctggagct ttacatggtc ttggatttgg tgataatgct
     8881 aaggcagcca tcatcgctcg aggtttagca gaaatcaccc gcctaggggt agcactcggg
     8941 gccagtccat tgacctatag cggcttatct ggtgtgggag atttgatcgt aacgggaact
     9001 tccatccact ctcgtaactg gagagctgga gatgctctcg gacgaggaga atccctagct
     9061 gatatagaag ctaatatggg catggtaatc gaaggaattt caacgactcg agcagcctat
     9121 gaactagccc aagaacttgg agtctatatg cccattacac aggctattta ccaagttatt
     9181 tatcacggaa ccaatatcaa agatgccatt tatgacatca tgaacaatga atttaaagca
     9241 gaaaatgagt ggtcttaacc ctctatagaa aggattttta tgacatcaaa agttagaaag
     9301 gcagtcatcc ctgctgctgg actaggaact cgatttttac cagcaaccaa ggcccttgcc
     9361 aaagaaatgt tgccaatcgt agacaaacca actatccagt ttatcgtgga agaggctctc
     9421 aaatcaggta ttgaagatat tctagttgtc actggtaaat caaaacgttc tattgaggac
     9481 cactttgatt caaacttcga attggaatat aacctcaaag aaaaagggaa aacagatctt
     9541 ttgaagctag ttgatgaaac aactggcatg cgtctgcatt ttatccgcca aactcatcca
     9601 cgcggtctcg gagatgctgt tttgcaagcc aaggctttcg tcggaaatga accttttgtc
     9661 gttatgcttg gtgatgactt gatggatatc acagacgaaa aggctgttcc acttaccaaa
     9721 caactcatgg atgactacga gcgtacccac gcgtctacta tcgctgtcat gccagtccct
     9781 catgacgaag tatctgctta cggggttatt gctccgcaag gcgaaggaaa agatggtctt
     9841 tacagtgttg aaacctttgt tgaaaaacca gctccagagg acgctcctag cgaccttgct
     9901 attatcggac gctacctcct cacgcctgaa atttttgaga ttctcgaaaa gcaagctcca
     9961 ggtgcaggaa atgaaattca gctgacagat gcaatcgaca ccctcaataa aacacaacgt
    10021 gtatttgctc gtgagttcaa aggggctcgt tacgatgtcg gagacaagtt tggcttcatg
    10081 aaaacatcca tcgactacgc cctcaaacac ccacaagtca aagatgattt gaagaattac
    10141 ctcatccaac ttggaaaaga attgactgag aaggaataac aaaatcattt atataaagat
    10201 tagccacaca taaattaagt aaattctcta cttgaatcta cctatttaat aaaaactaat
    10261 gaaaacgcta tacttgtatt tgttttttca ttaaaataag agtagaataa attagtatag
    10321 taaaacaaaa aagcaccgaa tcggtgcgca ctttttcaag ttgtgtacgg acaaagcctt
    10381 attttaactt tgctatgttg tttcgaatgg ttccaaaata ataaataatt ttaaatttga
    10441 cttaactgtt ggagtagtca tggttaaatt aaatcaaccg agccgaacat aagttgttta
    10501 attttgtgga agctattaat aaaaatataa taagggagaa agataggtgt aattttaatt
    10561 ttaaagtaat tgcggacact atcaaagtaa aagattatgg agaacaaatt tgtagaattt
    10621 atcgaaaaca ataaaaaagt aatcatttca tcagttgcag ttggtgttgt attggtatta
    10681 gggtttggat ggtattcata taaccaacaa caagcagaac aacaagcaaa aattgtacaa
    10741 ttagaaaaag atagcaaatc agacaaagaa caagttgata aactatttga atcatttgat
    10801 gcatcttcag atgaatctat ttctaaatta aaagaactat ctgaaacttc acttaaaacc
    10861 gatgcaggta aagactatct taataacaaa gtcaaagaat catctaaagc aattgtagat
    10921 tttcatttgc aaaaaggttt ggcttatgat gttaaagatt cagatgacaa atttaaagat
    10981 aaagcaacct tagaaaataa tgtaaaagaa atcaataaac aaattgattt tatcaagaaa
    11041 gttgatgaaa ctttcaaaca aaaaaaattg gatgaaactg taaaatctct tacagatatt
    11101 gcagacaaat tccaaaaaca aattgatgtt ctgaagaaag aagaagaaca aaaagcatct
    11161 gacaaagcta aagaagataa gaagaaagaa gaatcaactt catctcaatc ttcaaatagt
    11221 tcatctcaag catcaagcag ttcttttagt tcatattctg gtaattcaga ttatgctcca
    11281 gaacaaacat acacagctga taatagccaa tcttattcag gttcaactgg tggagacaat
    11341 agtaactata aagcaccagc tgctacagac aacggaggaa atgatggcta tattcttggg
    11401 cacgtaactg gtgcagatgg atcgcaaaga gatttttatt ttaaccgttc aaacggagat
    11461 gttcgtgata caagcggcaa tcacgtagga aactttggag ggggcattac agattttaga
    11521 caacgttaat aactatttta gggctgtgtt gtttcgaatg gttccaaaac acattaaaag
    11581 ctactcattt tttaagtagc ttttttctta ttcaagttta catattagtt gtcacaaccc
    11641 cattcccttg tagaaaagca aaatggcgag tcctacgaac aagactaccg ctcctaatct
    11701 ctggctggta ttatacatcc gtttttctcc tctaactgga aagataactg ctagaaatgc
    11761 gccaccaact gcaccaccga tatggcctgc taggctgatt cctggaatca gaacacttcc
    11821 aataatgtta accacaaaaa gtgtcagata ggattgccct agctgttgga tataaggatt
    11881 gcgagttgca tagcgaagaa caataatcgc ggcaaatagc ccataaagag aggtagaggc
    11941 gcctgctgct aaggatttag gactaaatac aaaaacaaag agattgccca tcattcctga
    12001 taagagatag agaaaaaaga actgcttaga gccgaaaatc tcctctacct gccttccaag
    12061 ataataaagt gaaagcatat taacaatgaa atgttcccac ccaatatgaa caaaaatggc
    12121 agacaagaga cgccaaacct gctcgggaaa gaggcgaata gctggcccat acatggctcc
    12181 aaatcgaaat aatgtatctg ccctgtcaaa gtttccgcct gcagtgacca acattagtaa
    12241 aaataccaag gccgtcacta agaggaagaa actcgtcaca gggtaacgtc tatcaaagat
    12301 ttccttcatc aattaatacc tcctgaacag gaatatcatg gttttcaggt ataaagtcct
    12361 gaatttgaca aggatatatc gtactcaaag tacgaccaga aaaatgttcc aaatagcggt
    12421 cataatagcc tccaccgtat cctatccgat atcctttcgt cgtaaaagcc agaccaggaa
    12481 catgaatcaa atcaatctga gatgcatcca ccacttccac atctccctgt ggctccagta
    12541 aggcaaaggc agtttttacc aactgttgcg gatcatagac cacaaactcc atgcgcccct
    12601 tgggataagt tttgggtatt aaaaccttct tgccgtcctt cagcgcctgc tcaatcagtt
    12661 cccgcgtttg aaactcatga gaaaaagaga ggtaggttgc gatgaccttg gcttcttggt
    12721 agaagggatg gtgtaaaagc cgctcggtta aagcttggtc tatagcctgt ttttgctctt
    12781 gagatatagc cttcatttca tgcaagactt gcttgcgtaa ttccgatttc atagacaagc
    12841 cctctattct gctgccttct ttttcaggaa actagacacc gcagccaccc caatagctaa
    12901 gacttcttcc ttaggactca tttgagggtg atgaagagcg tagggactat cgatacccag
    12961 ccaaaacatc acgccatcaa cctttgaaag gagataacca aagtcctcgc ctgtcatagc
    13021 aggttcgata tcaatcaact cgattccgtc tttttcgtca aagaagtcca tcagttcacg
    13081 cgccaaggct ggattgttct caacaggtag gtatccacct tgtttgagtt ccacttcgac
    13141 ttccatatca aaggcagctg caaccccttc tgcaactgtt tttaccctct tttgcaccaa
    13201 gagactcatg tcctgtgtca aggcacgaat agttccatgt aaaaaagctg tttctgtgat
    13261 gacattgttg gtggttccag cttgaaaaac gccgaaggtc accactgctc cctcgattgg
    13321 gttgacattg cggctaacaa ctgactgcac ttgggtcaca aagtaactag ccgctaccaa
    13381 ggcgtcattg gcttcatgag gaaaagctgc gtggccacct ttgcctttga aacggatctt
    13441 cacctcgcaa gttcctacaa agagtgtatg agtattagtc gcaatctggc cgactttcaa
    13501 atctggacga acatggagac catagaattg gtttggcaac caatctccaa aagcaccgtc
    13561 ctcatacatg agcataccac cagcttcatt ttcttcagca ggctgaaata gaaagagcag
    13621 attattcttg ggttgctcct caagggcgcg ctcaagacag cctaaggcaa tggtcatatg
    13681 aaaatcatga ccacaggcat gcatgcgacc ttggtgttga gaagcaaaag gtagacctgt
    13741 ttgttcgacg ataggcaggc catcaatatc tgtccgccaa ccaatggttc gctccggctg
    13801 acttccctgc aggtagacca aaatccctgt ccgccaagta cgaatttgaa caaaatcctt
    13861 gcccgtagtc aatttctcaa tcacatccag caaataagcc tgagtcttga actcctccaa
    13921 gccaatctct ggtatctggt gtaaatctcg tctagtctga atcaaatcta acatctatct
    13981 gtcctccgat atagcagaaa gaggctggaa aaagggttcc gcctcttttt tacttttaca
    14041 attacaaggt acgaagcgca tcctctagcg ctgttttttg ttgggtttgg gcatcaattt
    14101 ctttgatgat acgagctgga acacctgcta ctaccacgtt ttctgggaca tcttgggtaa
    14161 cgatagctcc tgcagcgaca actgaaccac taccgatttg gactccttcg ataaccactg
    14221 cattagcacc gataagaaca ttgtctccga cacggactgg ttcagcacta gctggctcaa
    14281 tcacacctgc caaaactgca cctgcaccaa cgtggctatt ttttccaacg atggcacggc
    14341 caccaaggat ggcacccatg tcaatcatgg ttccagcacc gatttcagca ccgatattga
    14401 taacagatcc catcatgata acagcattgt caccaatttc cacctggtca cggataatag
    14461 cacctggctc gatacgagcg ttgatagcac gcttatctag caaaggaact gcagaattac
    14521 gagcatcttg ctcgacaaca taatcttgat tttctaccaa accttcaaga agcggagcca
    14581 cgtccttcca gtctccgaat aggacatttc ctagtttgac aacagagcta ggcacagcag
    14641 ttgcgagttg cccctcaaag gttactttga cactggtttt cttttcagca ttggcgataa
    14701 attggataat ttcttgagcg ttcatttttg tagcagtcat aggtgcctcc tggttcgtta
    14761 taatgatacc tattctacca aaaaaggcct caaatttgaa acctttttgt ctgtttttag
    14821 gtatgatttt ttagggatgt gagataaaac gtgctgtcgg taaaagcaag cccctaccga
    14881 tacaacctaa aaacactctt cacaactatc tccccgtgtt ttattgacta ttctagtata
    14941 gcacactttt agaattaaga aaagactttt tatctacttt ctttcgcttc ttctatagac
    15001 aaaaatatca tgggtaaaat aatcaaggct atagctagaa ggagggacca atccactact
    15061 aatcctaaga acaaaacact caagagagca gaagagagag gttcactggc actgataacg
    15121 gcaaccacca aaggagaaac caaggacaca gccttcatgg aaatgaaaaa agcaaaagcc
    15181 gttccaaaga aagcgataat gaggcaaatc aagatactcc aaatatcaag agtaaaggaa
    15241 agctgataaa ccggcgagag gacattgcta aacaaacctg ccaaaatcat cccccaccca
    15301 accgtaggaa caaaaccata acgcttagca aaaggttggg gcaagataac attaaacata
    15361 acacccatgg cactcagcaa acctgttata agagctagcg gcgtcatgga taactgagag
    15421 agatctccct ttgtcgccat caagcaaaca cccagcatgg caaccaaaac atagaaaaca
    15481 gcgctttttg acgctcgttt ttgataaacc aagcgattgt aaaagaggat aaagacaggg
    15541 ctaataaact gtaaaatagt tgctgtcgta gcatttgagt attctacaca gagatagaaa
    15601 aaatactgga ctgaaaaaat ccccaaaata gcataggcta aaaagggcag gtaatttttc
    15661 ttgtctcgcc aaatatctag cacttgcgat tttaattgta ttgcagacca aatgagtaca
    15721 atactccctg ccagtgtcaa acgcatagag gtaatccagc ccgaagacac ctgataatga
    15781 gtaaagaagt actctcctaa aattccacag attccccata ttaagccgga taggagcgaa
    15841 taaatttttc cgttaacaat ctttttctga tactgattca tacccttatt gtaacacgaa
    15901 aggaaaaaag tggcaatcca ttgattggcc acttcattta gagaattatc gtctcgccct
    15961 tgaagaagaa ggtcgtgtag tacttgagtt actgctatcg ctagaactac tacttgaact
    16021 gctggagctg gatggagttg gtagactccc cacaatacta gaccaagcat tctgataatc
    16081 cgcatcactt ccgccaatag caaagcgata acttgtcgct ggcgctcctg acttattagc
    16141 ccaatagctg gtaacagtcg aacctgtgac ctctacctct tttccttcaa cagaaacctt
    16201 ccctggtttt tgacctgttg atttcaagac ttccgatttc actacactag gatctaaagc
    16261 aaagcgctcg ttcccccaaa tgcttgggga agcttgctga atcgcattta ctagatgagc
    16321 catgtaatta gagttattag aataacctgc tctacgtgac aatgaatgat tatcatcatg
    16381 cccaatccag ccacctaggg ttaatctagg tgtcgaaagc atgagccaca tattttcgtc
    16441 ttggttggtt gtaccagtct tcccaatcca atctgcatta gccagagtag gatttaaaga
    16501 agtcaggtta gacttgaagg ttgttgtcac acgagaggat agaacttctc gtagcaatcc
    16561 ctgcataatc gtcgcagtag cttttgaata gacttgaacc ggtttatcct gatactcata
    16621 caccactcta ccatctgctg cttcaatctt tgaaatcaca tgcttctgat gataaactcc
    16681 attattagct aaggtctgat agccattggt atgctgggca actgtgactt caataccacc
    16741 acccattggc aagctctcaa taccgtactc aggaatctcg taacccatct tttccatata
    16801 acccttgaca tcaacaccat tttcacggag cagactatag gtccagtaag cagggatatt
    16861 ccatgagtag ttcagagctt ctcccaaggt catcattcct gttcccttgc tattagcata
    16921 cataatcgga ttgccattag caaagtttgt tggatagtta gatagaatcg tttcacttcc
    16981 catcaagccc tggtcaatag caataccgta ggccagcaag ggcttggtag tagaagctgg
    17041 cgaacgtttg gtatcaaagg catgattatt ttgattttct tgataattac gaccacctac
    17101 aaagcctaga atagcacctg tttggttgtc catcaagaca ttccctactt ctacacgacc
    17161 tgttccatcg tctaaaagat agccataatc agcaaccgca ctttgcatgg cagaatgaat
    17221 tttctgatct atggtagtag taatcttata accaccattt tcaatttcct tggctgccaa
    17281 atctcgataa aacttctgag ttgcctcatt tttcaactcc ttagcggaga cattgtctct
    17341 ctgagctaga tagtcataca tacgttcttg agcttctgcc aaagttgtaa agtataaata
    17401 gtctcgtgaa attcctgtaa ccgtgcccga tggtaaaaag tcctgtttaa ggtcataatc
    17461 cttgtactga gaatactcgt ctttgcttaa tgcacctgta cgatacatac tgtaaagaac
    17521 tgccttagcc cgtcttaagc caatttctag gtcttcatca ctcttcaact ccccagtatt
    17581 ttcataagga gagtaagtaa tgggactctg tggaagtcct gctaaaaatg ctgcttgagg
    17641 aacagtcaac tgactggcat ctacaccgaa aattccctca gctgcttgcc gagcccctgc
    17701 aatattctgt cccttattat ttcggccaaa gggagccaca ttgagatagg tcgttaaaat
    17761 ctcatcttta ttcatggcgc gttccaaggc aagagcatcc acaatctctg ccgccttacg
    17821 agccaaggtc ggcgcatccc caaccacctg ctgtttaatt agttgctggg tcaaggttga
    17881 acccccacta gaggaaccca aacctacaaa tttccccaag gtcgcacgaa tcaccgcctt
    17941 gggtactaca cccttatgtt ctttaaagtg ttcatcttct gtcgcaatga tagccttctt
    18001 cagattttcc gaaatttgct cagatgagat agaagtgcgc aacaaatcac tctctatgga
    18061 agcaatcacc gtcccgtccg aataggtaat ctctgaaata gaagagatgt ccttgacctg
    18121 attcaccaat tcttctgtct gaggcacccg aaccttgtca aataaggcca ctccgtaccc
    18181 caaagcaatc ccagctccca acattcctcc tagaaaaccg agtacaaaga gtaagttaaa
    18241 taaggctttt atactcagta aaatagctgg gaaaatggct gacttatcta aggttttaga
    18301 ttttttggta cttgaacctt tcttgccagg tctagctgat tttttatttt tttgtttttg
    18361 ctggaaaaat tccagcattt ttcgttttaa ttcatttaat tgattttgca tggatttcct
    18421 cactttatct attataccac aaaagggaaa ttttcaataa aatagccact ttcttcccta
    18481 ttctgctagg ctattgccca agtttgtgat acaataggta gaaacaataa ttttaaaaag
    18541 gagaaaaaac acatgcacat ttttgatgag ctaaaagagc gtggtttgat atttcaaacg
    18601 actgatgaag aagctttgcg taaagcccta gaagaaggtc aagtttctta ttatactggc
    18661 tacgatccaa ctgctgacag ccttcaccta ggccaccttg tcgcaatctt gacaagtcgt
    18721 cgcttgcaac tagcaggtca caaaccttat gcgctcgttg gcggtgctac aggtctcatc
    18781 ggagatccgt ccttcaaaga tgctgaacgt agtctccaaa caaaagacac agtagatggc
    18841 tgggtcaagt ctatccaagg acaactttct cgttttcttg actttgaaaa tggcgaaaac
    18901 aaggctgtca tggtcaacaa ctacgactgg tttggcagca tcagcttcat tgacttcctc
    18961 cgtgatattg gaaaatactt cacggtcaac tacatgatga gtaaggaatc tgtaaaaaaa
    19021 cgaatcgaaa caggaatttc ttacactgag ttcgcttacc aaatcatgca agggtacgac
    19081 ttcttcgtcc ttaaccaaga ccataatgtc actcttcaaa tcggtggttc tgaccagtgg
    19141 ggaaatatga cagctggtac cgaattgctt cgtcgtaaag cggacaagac tggtcacgtt
    19201 atcactgttc cactaatcac agatgcaact ggtaagaaat ttggtaaatc agaaggaaat
    19261 gccgtctggc tcaatcccga aaagacttct ccatacgaaa tgtaccaatt ctggatgaac
    19321 gtgatggacg ctgacgctgt tcgcttcttg aaaatcttta ctttcttgtc acttgatgag
    19381 attgaagata ttcgtaaaca atttgaagca gcgccacacg aacgcttggc tcaaaaagtc
    19441 ttggctcgtg aagttgttac acttgttcac ggagaagaag cctacaaaga agcacttaac
    19501 atcactgagc aactctttgc aggaaacatc aaaaaccttt ctgtcaaaga gctcaaacaa
    19561 ggacttcgtg gtgtgccaaa ctaccaagta caggcagacg aaaacaacaa tatcgtggaa
    19621 ctgctcgtct catctggtat agttaactca aaacgccaag cccgtgaaga cgtccaaaac
    19681 ggagccatct acgtaaacgg cgaccgcatc caagagcttg actatgtctt gagtgacgct
    19741 gataagttag agaatgaact gactgttatc cgtcgtggga agaaaaaata ctttgtattg
    19801 acttactaaa ctattcaaca tttatctata aacaaaggag ttagcctcga gaaaggtaac
    19861 tcctttttgc tgttaataac tctcatctat ctatttttaa tagacaggct acgcaggaca
    19921 atgcgcaagg ttgttagatt atgtaagata gagagatttg aaggactgag ccaattaaat
    19981 aagccgaagc caatcaaact actatttacg acaacggtat cttgaatatt tttcttgatg
    20041 agtgtttgca aagatgatga taacgaatcc aactcttgga agaaatccaa acgattatct
    20101 aacaataaga tatcactcat ctgcttagaa atatctgcac tctcattcat caccacaccg
    20161 atatctgata gagttaaagc cgctgagtca ttcaatccat ctccaaccat caaaatagtg
    20221 tgacctgctt tctgcagttt ctctactaac tcaaatttcc catcaggttt caagtctgta
    20281 tagacctgat caaagggcaa atctttgact aattcctctg tcctagtcaa ggtgtctcct
    20341 gttgccagaa tcaatttttt cccctgtgcc ttaagtttat ccaaggctgt ttttgcttct
    20401 tttctcaaag gagtatgaat gcagaacatt ccaatcaatt cattttgata agccaagaat
    20461 aagagattgt agtgactctt gtactcttca attaaagcat tttgttctga actgatatga
    20521 atctgctcat cctgcatcaa gacataattc ccaataagaa ctggttggcc atctatatga
    20581 gatttgatcc ccttgcttgc gatatattgg agtttcccat gcatttcctc atgttcaatt
    20641 ccctctatct cagcttgctt gacgatggca ttagcaatag gatgataaat gtgttcctca
    20701 agacaggcac tgattctgag aatatcttcc tcactatagt ctccaaaagg taacaccttt
    20761 tcaactatag gataactagt tgtgattgtt cctgtcttat caaacaagaa agtatcaact
    20821 tccagatatt tctccagaac atctccatcc ttaatcacca tttcacggtt caacccttcc
    20881 ttgataactg tcaaataagc tacaggagta gagattttca aagcgcagga gaaatcgacc
    20941 aataggaaag aaatagcctt agaaaaagaa cctgtcaata ggtaagtcag cccagacccc
    21001 aagaaattat atttgacgac tttatccgcc atcttgatga aatagcgttg tttcgttttc
    21061 ttgttttctt cagatttctt catcaactca atcagctgta aaatacggct gttcatctga
    21121 ttatctgtta cacgaatgcg taactctcca gtttctaata ctgtatttgc acaaaccaaa
    21181 tcagactctc ttttttcaac tggaaaactc tctcctgtca aggaactttc gttgaccata
    21241 cctaaacctg aaactacttg tccatcaaac agaatttcat ttccttgaga taagatcaag
    21301 acatctccta tttgaacatc ggaactcttg atactaacaa ccgtatcgcc ctgtactagg
    21361 aatacatcgc tctcttttgc aagaagactc tgttctaaat ctgttgcagt ttttttcaag
    21421 gaccactgat ctaaatgatt ccccaaatca agcataaaca tgatattgct agctgtcttg
    21481 gattggttca taaacaagga caataaaata gccgaacagt ccaagacttc catcgttagt
    21541 tccttacgcg ctagtgtttg ataggcttct ctaatataac ccaaagcctg ataacaagtc
    21601 catatatagc gaataggata cggcacaaaa ctacgaaaaa gtacacgctt aaccgctgca
    21661 cctgaaacaa tagaataagc actctcttct ctacgaatgg gaagagtcat caactcagaa
    21721 actttccctt tatcaattct ttttaaaaag gcttctgcat tatctaatac agaaaagcct
    21781 tcttttatgc gtagagtaaa gtgctgttga tccatgtaaa actggataga ctcaatcccc
    21841 ttttcatctc tcgccaagga acgaagatag tcttgaatat ccaaggtaag tgaaaaagaa
    21901 gatgatagtc ggatatgttg gtatcctcta tgtagcactt taaaagacat attattcacc
    21961 tataaggcta tctaattgct cttctttttt ctcttgctcg tacaaatatt tggcatcttg
    22021 caagacatcg tctccatgtt gcttcacaac agaaacagat gcatctagct cgtctttcaa
    22081 cttgtaagcc ttagccaaag ctttagaata acctttttta gcttccttac ttgctaagat
    22141 tttcaaacca agggtaccaa atgcgacacc acccaaaaat aatgaagatt ttttcgcaac
    22201 ttttgcaacg gttaatactt cttttaacat acttatttcc tccttatcat tattatatag
    22261 caatttagat ataaaagcaa tttcattcta taaattggag aattagtttt atttctactg
    22321 aatctcccat ctacttattc ctaaagttgc tttcatttgc ctcttttgat acacttaaac
    22381 tatgaataca aatctcaagc ccaaacttca gcgttttgct tctgcgactg cctttgcctg
    22441 tcctatctgt caagaaaatc tgactctgtt agagactaat ttcaagtgct gcaaccgtca
    22501 ttcttttgac ttggcgaaat ttggctatgt caatctagca cctcaaatca agcaatctgc
    22561 taactatgac aaggaaaatt ttcaaaaccg tcaacaaatc ctagaagccg gcttttacca
    22621 agctatctta gatgctgtat ctgacttgct tgcaagctca aaaactacca caacaatttt
    22681 ggatatcggt tgtggtgaag gattctattc tcgcaaacta caagaaagtc actctgaaaa
    22741 aactttctat gcctttgaca tctccaaaga ttcagtccaa atcgctgcta aaagtgaacc
    22801 caactgggca gtcaattggt tcgttggcga cttggcacga cttcctataa aagacgctaa
    22861 catggatatt ctgcttgata tcttctcacc tgccaactat ggagaatttc gtcgcgtttt
    22921 atccaaagac ggtatcttga taaaggttat cccaactgaa aatcacctca aagaaatccg
    22981 tcaaagagta caggaccagc tgacaaacaa ggagtattct aaccaagata tcaaggagca
    23041 tttccaggaa cactttacca tcctatctag tcaaactgcc tctctgacta agactatcac
    23101 agcagaacaa ctccaagccc tactcagtat gactcctctc ctctttcacg ttgaccagag
    23161 caagattgac tggagccaac tgacagagat taccatcgaa gcagagattt tggttgggaa
    23221 agcattctaa actagacttc ccaaaggtat aaaacttacc gaaaatcttc aatattataa
    23281 aaacgcataa gaacaggtac acaaacctta atcttatgcg ttttgttata gtttccatac
    23341 acattaaggg gaaatagttg aaatcagttc tcttaataac cattgaatac catatactac
    23401 atttacccca aatatgatat aggccgtata aatcaagtat ttcgattttt cccgcctcaa
    23461 agaatagatc ttatacaaaa taaataaatt taaaataata aataatagag acaaaatctt
    23521 cctccaaaat caatattaaa agtagccagt caatcatagt tctaatcttt attttcgatt
    23581 cgaaattaca aacttatcaa tgaacaataa gtgatataag gccagtacca gaccccaaac
    23641 gctaccacga aaagagaatt cttgatgatt gagagtaaac aaatcatggt taccaatata
    23701 gaggcaggtc aaaataacaa ataaaatcca aaataaatcc gtccatttat attttgaaaa
    23761 atattttttt aacataatag catatttttt tgactataat aacagtatat gataaaatgt
    23821 aagcagatac aaataaaaag gagaaaagct catgaacaaa ttaatgaaat ttatttcggt
    23881 ttttttgacg tcaattgtgt taattgtatc agcgattcca agtgtttcag ctgtatacgc
    23941 ttctgaacaa gtatcacaaa ttgaaacaaa tatggaactt caacctgtca cttctctaac
    24001 agaagaacaa atcaatacac ttgcaaacga aatccaatct tttcatccag acgtctcaca
    24061 acaatggatc aaagaagtaa ttaaccgaca attacaaggc gattatacaa tcccacctac
    24121 atactctcca tttagagcag cttggcaagg tattacagtt aatcaaatgg gtgctctatt
    24181 agatactgca atagctttag cattaggagg aactactgca ggccttgcaa atctaattaa
    24241 agtaaaagga aaacatgcag caaaaagtgc tattcgttca gcaatttcta gatatctagg
    24301 tagttggttt gtaaatgatg ttgctttaga attcgctatg aatttattat caccggggac
    24361 ttatttagca caattatggg ataaaaatga tgccattcct aacaacggaa ggattaactt
    24421 ttaatcatga gatatacaat aaaattaatt gggtataacg tattttcgtt gtttatattc
    24481 tttatcttat caatgttgtt taaagttccc tttaggtggt ggatcagcat tgcaatgacg
    24541 acttcgtcgt acattgtata taattactta aagaaaaaga gagaaaagga atgatcttat
    24601 accagatcat tccttttctg ctttctgtaa atccctcgga gtgtgtttgg cgctttgata
    24661 cgaagtgtca aagctgtata aacgttacta tttccaaaaa agtaacagaa aattcctgct
    24721 ttgtaggact gctttgggtg agtaatagac atgtcgactc accctatctc ctgatggcga
    24781 aaagaattta gcaatggtgc aagttgttct gaactcgaga aaaaacatgc cgaaatcgaa
    24841 gaaaagcgtg cagaacttga agcgaagaag caagaaatgt tgaatcgctt ggataaatag
    24901 aatttagaaa acagaaaaac taaaaagaat gtagggttta tttccctaca ttcttaaaat
    24961 aacttagtac ataaatgaca atgctgccac tgccgtcaat attgcaaaaa ctattttcca
    25021 aattttttta ttttttccaa aaatcttatc aggtaacaag cttattacaa gaaaggtaat
    25081 aaacaacacc aatttaagtg tgtatatcat aaaaacacct tctttcctac aattatatta
    25141 taatacttta tgtaagcgaa tacaagagat gtgaggtaac caactacgaa aaaatataag
    25201 gctgaagaca gtaaaaacca gcatttaaag ccttcactgt atctaggatt tccctatttt
    25261 tagacaagat tgacccaaat ccacagcatt taaaaaagcg aatttcaatc gaaactcgct
    25321 tttttacaaa atgtattagt ataaatttgt atcttatact caatgaaaat caaagagcaa
    25381 actaggaagc tagccgcagg ttgctcaaag caccgctttg aggttgcaga taaagctgac
    25441 gtggtttgaa gagattttcg aagagtatta gttcaagtgc cagatgtctt cattatactg
    25501 agcgattgta cggtcagatg agaagaatcc tgctttagaa atgttaacga tgactttatc
    25561 caaccatgcg tcacggtctt cgtagtcagc aagcatttgc tctttgactt tgatgtagtc
    25621 ttccaagtca agaagagtca tgaaccagtc tttgttgatc aattcattgt aaagacgttc
    25681 caagcgctct ttgtttccag ctgcaagaac tgcatcacta acgatgaagt caaccaatgg
    25741 tttgatagct tcacgagcgt agaattcgct tgatttgtaa gctgcttttg cgtaaaggtc
    25801 gataacagtt tctgaatctt caccgaagat gtagatgttt tcttctccaa ccaactcagc
    25861 gatttccacg ttagcaccgt ccatagtacc aagtgtcaaa gctccgttca acatgaattt
    25921 catgttacca gtacctgaag cttctttaga agcaagtgaa atttgttctg agatatcaca
    25981 tgctgggata aggaaacttg ctgcagtaac gttgtagttt tcaaccataa ctacttgcaa
    26041 gtgtggagct actgctggat cgttagcaat aacttctgac atgcaaagga ttaaatggat
    26101 aatgtcttga gcgattgtgt aggctggagc tgctttacca ccaaagaaga ttgtgattgg
    26161 acgagcaggg atgttaccag ctttgatgtc aaggtatttg tggatcacgt acaaagcgtt
    26221 catttgttgg cgtttgtact cgtgaagacg tttgatttgg atatcaaaga tagaatttga
    26281 attgatttcc acaccttggt gttctttcaa gtgacgagcc aatttacgtt tgttgtgagc
    26341 cttgatgctt tccaattttt ctttgacagc tgctttgtct tcataagaca aaagtttttc
    26401 aagctcatct gcttcatggt gccaaccatc tccaagaatc tcatctaagt agtgagacaa
    26461 tcttgggtta gcatgcataa gccaacgacg gaaagtgata ccgtttgttt tgttgttgaa
    26521 cttttctggg taaaggtcgt agaaggcttt caactcagaa tttttcaaga tttcagtatg
    26581 gagtgctgca accccgttaa cactgtatcc gtagtggata tccatgtgag ccatgtgaac
    26641 acgtccgctc tcatcgatga tttgaacagc tggatctttg tactctgcct tcacacgacg
    26701 gtccaattct tcgatgattg gtaccaagtg aggaaccact tcttgcaaga attcaagagg
    26761 ccatttttca agcgcttcag caaggattgt gtggttagtg taggcagtca tgctacgaac
    26821 aattgagatt gcttcgtcaa gctcgatacc acgtgcagtt aaaagacgaa tcaattcagg
    26881 aatcaccatt gatgggtgag tatcgttgat ttggacaact gcgtagtcag caaggtcatg
    26941 caagttgctt cctttttcga ttgcttcgtc gatgatcaat tgcgcaccgt ttgaaaccat
    27001 gaagtattgt tggaagatac ggagcaattc accttgacgg tcactatcat ctgggtaaag
    27061 gaagagagtc aagttgcgag cgatatctgt cttgtcaaag ttgataccat ctttaataat
    27121 agaagaatca actgaatcca agtcaaacaa acgcaagcgg tttttagtcg ctgtttcata
    27181 accagtaaca tcaatatcgt aaagagttga tgtcaaagta aagtctgcaa atggtacttg
    27241 gtagctacgg cttgagcaaa ccaaccagtt ttgctctgtc aaccatgcat ttggaattgt
    27301 ttcttgttgg ttgtttttaa gaacttgttg gaaaagacca aagtggtagt taagaccaac
    27361 accgtcacca ttcaaaccaa gagtagcaat tgagtcgata aagcaggcag ccaaacgtcc
    27421 caaaccacca ttaccaagag atggttccaa ttcaacttct tcaacttcga tcaagtcttt
    27481 acctgcagct gcaagttctt ttttaacatc gtcgtaaaga ccaaggttaa tcaagttgtt
    27541 tgacaagagt ttaccaatca agaactcagc tgagatgtag taaacttttt tcttaccagt
    27601 gttgactggt ttttggctgc ttgcaagctt gctgtagtta agaagagcaa ggtaaagctc
    27661 ttcattgcta cattctgcaa tggttttatt gtaacgattt tgtacaaatt cttgtagtga
    27721 taacatgttt agttgtctcc tgattattgt cttatttctt taaatctacc aaattttcat
    27781 taattcggcg ataaattgtt gtcaagtcaa gcaaaccttc ctcgacagct ggtgtcaatt
    27841 gatcttcagt catacgccaa gaccagtttc caccaagggt agatgggaag ttcatacgag
    27901 ctgcctcatc caattctagt aaatcttgca tagtcgcaat tgccataaag ctaactgatg
    27961 aaaatactgt acgaagcata gcgtgtacca ctgtttcgta ttctttacgg ttcgtgtaac
    28021 gagccatgta ctcacgagtc gcatcatcaa tctcattacg gtaccaacca agaaccgtat
    28081 tgttatcgtg tgttcctgtg tacataactg agttagcagg tgccaagtgt gggctatcaa
    28141 tgctttcgtc ttctgggttg aaggcaaatt gaagaatctt cattcctggg aagccagtac
    28201 gttcacgcaa ttcgatcact tcatctgtca tgaagccaag gtcttctgcg atgatgttta
    28261 gctcaccaag ttcttcctta acggctgcaa aaagcttgta gcctggacct ttcacccact
    28321 caccaggtgc tgctgtatcg gaaccagcag ggatttccca ataagattcg aagccacgga
    28381 agtggtcgat acgaacgata tcgtagattt tgaagctttc acgcaagcgt tcaatccacc
    28441 atttgtagcc gtctttgtcc attgcttccc agtcatagat tgggttaccc caaagctgac
    28501 cagttacaga aaactcatct ggtggacatc ctgcgataca agtagcctta ccattgacat
    28561 ctgttttgaa gagatgtgga tttgcccaca tatcacttga atcttccgct acgtagattg
    28621 gcatgtcccc aacgatttcg atgtggttgt cgttagcgta agctttcaat ttcaaccatt
    28681 gttggaagaa gaagtattga gtcacacggt ggtaaaccaa cttgtctgcc aattgctcac
    28741 gatagctttc aagtgctgaa gctttacgag cacgagcatc tgcatctggc cattcagtcc
    28801 aagcaagatt gtcaaaatgc tctttgatag ccatatactc agcaaagagc tcaagccatg
    28861 attggttgtc ttgagcaaat ttctcaaaat ctttaacata tccgacttca aagaaacgct
    28921 tcaccgcttt ttctaaaaga ggacgacgtg catagtagat tttagcatag tcaacttcag
    28981 acgcatcgct accaaagtca actccttcaa ggtcacttgc ttccaacaaa ccttgctcca
    29041 ccaagatatc taaatcgata aaatgagtgt ttcctgcgaa ggctgagaaa gattggtaag
    29101 gagaatcccc gtaactagtt gctcctaatg gaaggatttg ccagtaacgt tgttttgtac
    29161 ggaccaagaa atcaacgaag tcgtaagcac tttgaccaaa tgatccgatt ccgtaagctc
    29221 ctggaagaga agagatgtgc atcaacacac cactttgacg ttttttcata atagcacctc
    29281 gtgtgttaaa ataatggaac gttgcgtatt tttcagacgc aaacgtttgc gttacttata
    29341 agtatactcc ttttcaagca taattgcaag cgtttttaaa aaactttttt gattattttt
    29401 aaggagacta actcatttta gcaaagataa cttaaaacta tctaatccta aggtttgact
    29461 ctcacgagac agtatacaaa gtacaaaacc tccttaggga gcttgaattt atatgcaaca
    29521 aagcacaaac gtctatagaa aatagatata gattagaaat agggaggtag cccctcctga
    29581 tttccctctt tagacagatt ccatatattt ttattaaaaa tactgtattc ttatctattt
    29641 catacttttc ttctattaaa atgcaaaatt atgctatcaa atcaagctta aaaatttttt
    29701 aaaattttta caaaaaatac ttgcaaccgt tttctattta tgctatacta agctcataaa
    29761 ggaaaacgtt tgcgtttcct tatcaataaa acttgctatt ctttgggagg aatacactat
    29821 gtcatctaaa tttatgaaga gcactgcggt gcttggaact gttacacttg ctagcttgct
    29881 cttggtagct tgcggaagca aaactgctga taagcctgct gattctggtt catctgaagt
    29941 caaagaactc actgtatatg tagacgaggg atataagagc tatattgaag aggttgctaa
    30001 agcttatgaa aaagaagctg gagtaaaaat cactcttaaa actggtgatg ctctaggagg
    30061 tcttgataaa ctttctcttg acaaccaatc tggtaatgtc cctgatgtta tgatggctcc
    30121 atacgaccgt gtaggtagcc ttggttctga cggacaactt tcagaagtga aattgagcga
    30181 tggtgctaaa acagacgaca caactaaatc tcttgtaaca gctgctaatg gtaaagttta
    30241 cggtgctcct gccgttatcg agtcacttgt tatgtactac aacaaagact tggtgaaaga
    30301 tgctccaaaa acatttgctg acttggaaaa ccttgctaaa gatagcaaat acgcattcgc
    30361 tggtgaagat ggtaaaacta ctgccttcct agctgactgg acaaacttct actatacata
    30421 tggacttctt gccggtaacg gtgcttacgt ctttggccaa aacggtaaag acgctaaaga
    30481 catcggtctt gcaaacgacg gttctatcgc aggtatcaac tacgctaaat cttggtacga
    30541 aaaatggcct aaaggtatgc aagatacaga aggtgctgga aacttaatcc aaactcaatt
    30601 ccaagaaggt aaaacagctg ctatcatcga cggaccttgg aaagctcaag cctttaaaga
    30661 tgctaaagta aactacggag ttgcaactat cccaactctt ccaaatggaa aagaatatgc
    30721 tgcattcggt ggtggtaaag cttgggtcat tcctcaagcc gttaagaacc ttgaagcttc
    30781 tcaaaaattt gtagacttcc ttgttgcaac tgaacaacaa aaagtattat atgataagac
    30841 taacgaaatc ccagctaata ctgaggctcg ttcatacgct gaaggtaaaa acgatgagtt
    30901 gacaacagct gttatcaaac agttcaagaa cactcaacca ctgccaaaca tctctcaaat
    30961 gtctgcagtt tgggatccag cgaaaaatat gctctttgat gctgtaagtg gtcaaaaaga
    31021 tgctaaaaca gctgctaacg atgctgtaac attgatcaaa gaaacaatca aacaaaaatt
    31081 tggtgaataa aaaatttgtt caaggggggt ggaaatcaaa tccccctttg aatttatcaa
    31141 tagagacaca aataatttag ctttcttata aaaaagtagt atcctatgaa aggagttaat
    31201 atggaaaagc aacaacctag taaagcagcc ctgctgtcta tcattcctgg gttaggacag
    31261 atttacaata aacaaaaagc caaaggtttt atcttccttg gtgtaaccat cgtatttgtc
    31321 ctttacttcc tagcacttgc aacccctgaa ttgagcaacc tcatcactct tggtgacaaa
    31381 ccaggtcgtg ataattccct ctttatgctg attcgtggtg ccttccatct aatctttgta
    31441 atcgtttatg tactctttta tttctcaaat atcaaagatg cacatacgat tgcaaaacgc
    31501 attaacaatg gaattccagt tccacgcaca ctcaaagaca tgatcaaagg gatttatgaa
    31561 aatggcttcc cttacctctt gatcattcca tcttatgttg ccatgacctt cgcgattatc
    31621 ttcccagtta tcgtaacctt gatgatcgcc tttaccaact acgacttcca acacttgcca
    31681 ccaaacaagt tgttggactg ggttggtttg accaacttta caaacatttg gagcttgagt
    31741 accttccgtt ctgcctttgg ttctgttctt tcttggacta tcatttgggc tttggcagct
    31801 tctactttac aaatcgtaat tggtatcttc acagctatca ttgccaacca accatttatc
    31861 aaaggaaaac gtatctttgg tgttattttc cttcttcctt gggctgtccc agccttcatc
    31921 actatcttga cattctcaaa catgtttaac gatagtgtcg gtgctatcaa cactcaagta
    31981 ttgccaatct tggctaaatt ccttcctttc cttgatggag ctcttattcc ttggaaaaca
    32041 gacccaactt ggactaagat tgccttgatt atgatgcaag gttggctcgg attcccatac
    32101 atctacgttt tgactttggg tatcttgcaa tctattccta acgaccttta cgaagcagct
    32161 tatattgacg gtgccaacgc ttggcaaaaa ttccgcaaca tcactttccc aatgattttg
    32221 gctgttgcgg cacctacttt gattagccaa tacaccttca actttaacaa cttctctatc
    32281 atgtacctct tcaatggtgg aggacctggt agtgtcggag gtggagctgg ttcaaccgat
    32341 atcttgatct catggatcta ccgtttgaca acaggtacat ctcctcaata ctcaatggcg
    32401 gcagctgtta ccttgattat ctctatcatt gtcatctcaa tctctatgat cgcattcaag
    32461 aaactacacg catttgatat ggaggacgtc taagatgaat aactcaatta aactcaaacg
    32521 tagactgact caaagcctta cttaccttta cctgattggt ctatcaattg taattatcta
    32581 tccactgttg attaccatta tgtcagcctt taaagcaggt aacgtctcag cctttaaact
    32641 agatactaat atcgacctca attttgataa ctttaaaggc ctcttcactg aaaccttgta
    32701 cggtacttgg tacctcaaca ctttgattat cgccttaatt accatggctg ttcaaacaag
    32761 tatcatcgta cttgctggtt atgcttacag ccgttacaac ttcttggctc gtaaacaaag
    32821 tttggtcttc ttcttgatca tccaaatggt gccaactatg gccgctttga cagccttctt
    32881 cgttatggcg cttatgttga acgcccttaa ccacaactgg ttcctcatct tcctctacgt
    32941 tggtggtggt atcccgatga atgcttggct catgaaaggc tacttcgata cagtgccaat
    33001 gtctttagac gaatctgcaa aactagacgg tgcaggacac ttccgccgct tctggcaaat
    33061 tgttctacca cttgttcgcc caatggttgc cgtacaagct ctctgggcct tcatgggacc
    33121 tttcggggac tacatcctct ctagtttctt gcttcgtgag aaagaatact ttactgttgc
    33181 cgtaggtctc caaaccttcg ttaacaatgc gaaaaacttg aagattgcct acttctcagc
    33241 aggtgctatc ctcatcgccc ttccaatctg tattctcttc ttcttcctac aaaagaactt
    33301 tgtttcagga cttacaagtg gtggcgacaa gggataattt atccccgcca ccctttttca
    33361 ttttatactc ttcgaaaatc tcttcaaacc acgtcagctt tatctccaac ctcaaagttg
    33421 tgctttgagc aacctgtggc tagtttgcac tttgattttc attgattatt agcaattgtc
    33481 actgtaaata atatccttgt agcaagcaat ttttctccta gacttgaaat aaagcgcatt
    33541 tctctatata ataatactca tatagaaaac accttttaga aagataccta tgcttccata
    33601 tccattttcc tatttttcaa gtatttgggg gtttcgtaag cccctgtcca aacgtttcga
    33661 gctcaactgg tttcaacttc tctttaccag tatcttcctt atcagcttgt ctatggtacc
    33721 cattgctatc caaaacagct cccaggagac ctatccgcta gaaactttta tcgataatgt
    33781 ctatgaacct ctgacaaatg aggttgtcca ggatctctct gaacatgcta caattgtcga
    33841 tggcacatta acttatactg gaacagctag tcaaacccct tctgttgtga ttggtccaag
    33901 tcaaatcaag gaattaccta aggacttgca actgcatttc gatacaaatg agctagtcat
    33961 cagcaaggaa agcaaggagc tgacccgcat ctcttaccga gccattcaga ctgagagttt
    34021 caaaagcaaa gacagcttga cccaagcaat ttctaaagac tggtaccaac aaaatcgtgt
    34081 ctatatcagc ctcttcctag ttctcggtgc gagcttcctc tttggtttga atttctttat
    34141 cgtctctcta ggagctagtc ttctccttta tatcactaag aaatcacgcc tcttttcatt
    34201 tagaaccttt aaagagtgct atcactttat cttgaactgt ttaggattgc cgactctgat
    34261 tacacttatt ttgggattat ttggccaaaa tatgacaacc ctgattactg tacaaaatat
    34321 tctttttgtt ctgtatctgg tcactatctt ttataaaaca catttccgtg atccaaatta
    34381 ccataaatag gagattttta tgcccgttac gattaaagac gtggccaagg ctgctggtgt
    34441 ttcgccttca accgtaaccc gtgttattca aaataaatca accattagcg acgaaacaaa
    34501 aaaacgcgtt cgcaaagcta tgaaggaact caactaccac ccaaacctca acgctcgtag
    34561 cttggtaagc agctatactc aggttatcgg attagttctt cctgatgact cagacgcctt
    34621 ctaccagaat cctttctttc catcggttct acgtggcatc tctcaagtcg catctgaaaa
    34681 ccactatgcc attcagatag caacagggaa agatgagaag gagcgtctca acgctatttc
    34741 acaaatggtc tacggcaagc gtgtagatgg gctaatcttt ctctatgccc aagaagaaga
    34801 ccctctcgta aaactcgtcg cagaagaaca gttccccttc cttatcttag gtaaatctct
    34861 atctcctttc atcccacttg tcgacaacgg caatgttcaa gctggttttg atgcgactga
    34921 atatttcatc aaaaaaggct gcaaacgcat tgcctttatc ggaggaagta aaaagctctt
    34981 cgtgaccaaa gaccgtttaa caggctatga acaggcgctt aaacattaca aacttaccac
    35041 tgacaacaat cgcatctact ttgccgacga gtttctggaa gaaaagggct ataaatttag
    35101 caagcgatta ttcaagcacg atccacaaat tgatgctatc atcacaaccg atagcctcct
    35161 agctgaaggt gtttgtaact atattgccaa acaccagctg gatgtccctg ttctcagctt
    35221 tgactcggtt aatcccaagc tcaacttggc agcctatgtc gatatcaata gtttagagct
    35281 tggtcgtgtt tcccttgaaa ctattctcca gattattaat gataataaaa acaataaaca
    35341 aatttgttac cgtcaattga tcgcccacaa aattatcgaa aaataagaga ctgggcaaag
    35401 agtcgttaaa agcaaaaacg catactatca ggtattgaaa aaacttgata ctatgcgttt
    35461 ta
//
LOCUS       DAVBOG010000020        34124 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.020, whole genome shotgun sequence.
ACCESSION   DAVBOG010000020 DAVBOG010000000
VERSION     DAVBOG010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34124)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34124)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34124
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.020"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(21..833)
                     /locus_tag="VQ865_001023"
     CDS             complement(21..833)
                     /locus_tag="VQ865_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000162344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3135371.1"
                     /translation="MTKKIIAVDLDGTLLNSDSQISDFTKKTIKKVAEKGHQVIITTG
                     RPYRMSKDFYRELGLDTPMINFNGSLTHLPDQVWDFEKCLTVDKKYLLDMVQRSEDIQ
                     ADFIAGEYRKKFYITNPNEEIANPKLFGVEAFQPEDQFQPELVTKDPNCILLQTRASD
                     KYALAKDMNAFYQHQLSINTWGGPLNILECTPKGVNKAFALDYLLKIMNRDKKDLIAF
                     GDEHNDTEMLAFAGKGYAMKNANPELLPYADEQISLTNDQDGVAKTLQDLFL"
     gene            1023..2441
                     /locus_tag="VQ865_001024"
     CDS             1023..2441
                     /locus_tag="VQ865_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HET3135372.1"
                     /translation="MDKLFKLKENGTDVRTEVLAGLTTFFAMSYILFVNPQILSQTGM
                     PAQGVFLATIIGAVAGTLMMAFYANLPYAQAPGMGLNAFFTFTVVFGLGYSWQEALAM
                     VFICGIISLIITLTNVRKMIIESIPNALRSAISAGIGVFLAYVGIKNAGLLKFTIDPG
                     NYTVVGEGADKAQATIAANSSAVPGLVSFNNPAVLVALAGLAITIFFVIKGIKGGIIL
                     SILTTTVLAIAVGLVDLSSIDFANNHVGAAFEDLKTIFGAALGSEGLGALVSDTARLP
                     ETLMAILAFSLTDIFDTIGTLIGTGEKVGIVATNGENHQSAKLDKALYSDLIGTTVGA
                     IAGTSNVTTYVESAAGIGAGGRTGLTALVVAICFAISSFFSPLLAIVPTAATAPILII
                     VGIMMLGSLKNIHWDDMSEAVPAFFTSIFMGFSYSITQGIAVGFLTYTLTKLVKGQVK
                     DVHVMIWILDALFILNYISMAL"
     gene            2494..3201
                     /locus_tag="VQ865_001025"
     CDS             2494..3201
                     /locus_tag="VQ865_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135373.1"
                     /translation="MKEKNMWKELLNRAGWILVFLLAVLLYQVPLVVTSILTLKEVAL
                     LQSGLIVTGISIVVLVLFIIGARKTQLASFNFSFFRTKDLARLGLSYLVIICSNILGS
                     ILLQLSNETTTANQSQINDMVQNSSLISSFFLLALLAPICEEILCRGIVPKKIFRGKE
                     NLGFVVGTIVFALLHQPSNLPSLLIYGGMSTVLSWTAYKTQRLEMSILLHMIVNGIAF
                     CLLALVVIMSRTLGISV"
     gene            3297..4277
                     /gene="folP"
                     /locus_tag="VQ865_001026"
     CDS             3297..4277
                     /gene="folP"
                     /locus_tag="VQ865_001026"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HET3135374.1"
                     /translation="MMKSLEGVTDMSSKANHAKTAICGIINVTPDSFSDGGQFFVLEQ
                     ALQQARKLIAEGASMLDIGGESTRPRPGSSYVEIEEEIQRVVPVIKAIRKESDVLISI
                     DTRKSQVAEAALAAGANLVNDITGLMGDEKMAHVVAKAGAKVVIMFNPVMARPQHPSS
                     LIFPHFGFGQTFTEKELADFETLPIEEMMEAFFERALARAAEAGIAPENILLDPGIGF
                     GLTKKENLLLLRDLDKLHQKGYPIFLGVSRKRFVINILEENGFEVNPETELGFRNRDT
                     ASAHVTSIAARQGVEVVRVHDVASHRMAVEIASAIRLADEAENLDLKQYK"
     gene            4279..5601
                     /locus_tag="VQ865_001027"
     CDS             4279..5601
                     /locus_tag="VQ865_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000658404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HET3135375.1"
                     /translation="MKEIENNQWIANYRTDQPHFGLERMVELLALRGNPHLKLKVLHI
                     GGTNGKGSTIAFLKKMLEKLGLRVGVFSSPYLIHYTDQISINGESISEARLEALMADY
                     QSLLEGEAVANLQGTTEFEIITALAYDYFASEQVDVAIMEVGMGGLLDSTNVCQPILT
                     GITTIGLDHVALLGDTLEAIAEQKAGIIKQGMPLVTGRIAPEALTVIDRIAEGKDAPR
                     LAYGTDYQVRHQESVVTGEVFDYTSAVRQGRFQTSLLGLYQIENAGMAIALLDTFCQE
                     DGRELASNDFLGQALEETSWPGRLEIVSRDPLMILDGAHNPHAIKALLVTLQERFADY
                     HKEILFTCIKTKALEDMLALLGAMPDTELTLTHFADSRATDESVLKEAAKSRNLSYQD
                     WHDFLDQNLTDKKEEKQTVRIVTGSLYFLSQVRAYLMERKNENGYTKD"
     gene            5582..6136
                     /gene="folE"
                     /locus_tag="VQ865_001028"
     CDS             5582..6136
                     /gene="folE"
                     /locus_tag="VQ865_001028"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HET3135376.1"
                     /translation="MDTQKIEAAVKMIIEAVGENANREGLQETPARVARMYQEIFSGL
                     GQTAEEHLSKSFEIIDDNMVVEKDIFFHTMCEHHFLPFYGRAHIAYIPDGRVAGLSKL
                     ARTVEVYSKKPQIQERLNIEVADALMDYLGAKGAFVVIEAEHMCMSMRGVRKPGTATL
                     TTVARGLFETDKDLRDQAYRLMGL"
     gene            6179..6991
                     /gene="folK"
                     /locus_tag="VQ865_001029"
     CDS             6179..6991
                     /gene="folK"
                     /locus_tag="VQ865_001029"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HET3135377.1"
                     /translation="MDQLQIKDLEMFAYHGLFPSEKELGQKFVVSAILSYDMTKAATD
                     LDLTASVHYGELCQQWTTWFQETSEDLIETVAYKLVERTFESYPLVQEMKLELKKPWA
                     PVHLSLDTCSVTIHRRKQRAFIALGSNMGDKQANLKQAIDKLRARGIHILKESSVLAT
                     EPWGGVEQDSFANQVVEVETWLPAQDLLETLLAIESELGRVREVHWGPRLIDLDLLFV
                     EDQILYTDDLILPHPYIAERLFVLESLQEIAPHFIHPILKQPIRNLYDALKK"
     gene            complement(7036..7353)
                     /locus_tag="VQ865_001030"
     CDS             complement(7036..7353)
                     /locus_tag="VQ865_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HET3135378.1"
                     /translation="MAFTNTHMRSASFGIVTSLPDDIIDSFWYIIDHFLKNVFELEEE
                     LEFQLLNNQGKITFHFSSQHLPTAIDFDFNHPFDPRYPPRVLVLDMDGRETILLPEEN
                     DLF"
     gene            7710..8156
                     /gene="rplM"
                     /locus_tag="VQ865_001031"
     CDS             7710..8156
                     /gene="rplM"
                     /locus_tag="VQ865_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003083327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HET3135379.1"
                     /translation="MNKTTFMAKPGQVERKWYVVDATDVPLGRLSAVVASVLRGKNKP
                     TFTPHTDTGDFVIVINAEKVKLTGKKATDKIYYTHSNHPGGLKQISAGELRSKNAVRL
                     IEKSVKGMLPHNTLGRAQGMKLKVFVGAEHTHAAQQPEVLDISGLI"
     gene            8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ865_001032"
     CDS             8175..8567
                     /gene="rpsI"
                     /locus_tag="VQ865_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HET3135380.1"
                     /translation="MSQAQYAGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     RLVINQPFAVTSTVGSYDVFVNVIGGGYAGQSGAIRHGIARALLQVDPDFRDSLKRAG
                     LLTRDSRKVERKKPGLKKARKASQFSKR"
     gene            complement(8829..9251)
                     /locus_tag="VQ865_001033"
     CDS             complement(8829..9251)
                     /locus_tag="VQ865_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3135381.1"
                     /translation="MRFIVETFPIFSISNDLLQLLTSWKKQQKYELAKFGIISNPEQF
                     IFTYIDTKGNINKPLHSDYLNNKMKTIRKRHPELTHATPHKLRHTGATLAKQAGMSLE
                     AISEALIHSDTGTTQIYVNTSNVVPMAVGEFALQSLKQ"
     gene            9398..9574
                     /locus_tag="VQ865_001034"
     CDS             9398..9574
                     /locus_tag="VQ865_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135382.1"
                     /translation="MSLDIDKEKMTIMGIAFENRSVFKSVWYALSTNMIEGWRPTVSD
                     VEKLRDEALALGMT"
     gene            9976..12189
                     /locus_tag="VQ865_001035"
     CDS             9976..12189
                     /locus_tag="VQ865_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000688702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HET3135383.1"
                     /translation="MKIFKGEFYRISVLTDKLVRLEYSRTGNFEDRTTQLIYNRDFGQ
                     VSLDYIETSNVLDIMTDYFHLHFNKGEFNAENLFIELKGNFAVYGSRWYFGESIETLK
                     GTARTLDKADGAISLEDGIISRNGIALLDDSQGFIWDEQSGYIERENQIDLYFFAYGH
                     DYRGAIRDFYHLTGSTPLLPRYALGNWWSRYWPYTSDEYLDLIDRFETEKIPLSIGVL
                     DMDWHITDIPARFGSGWTGYSWNRNLIPNPEQLLQQLHDRKLKLSLNVHPADGIRAYE
                     EAYPQIAKRLGLNVELEEPAIFDFFNPSFREAYFKDVHYELEKQGVDFWWIDWQQGTQ
                     GMLDPLWLLNHYHYQDSCKNAEGGLILSRYAGPGSHRYPVGFSGDTIISWNSLRFQPY
                     FTATASNIGYSWWSHDIGGHMLGDYDEELQTRWLQFGVFSPITRLHSSRSPFNSKEPW
                     FFSETTSKIMKKYLRLRHQMIPYLYTMNVKTHEEGAPLISPIYYFYPENDESYNVPNQ
                     YFFGTELMVAPIVEKMDLTFQSAKVDVWFPEGEWYDFFSEKKYTGGVKLSVYRDISTT
                     PVFAKSGAIIPLVGSEIGMGVDLPEVVDWYVFPGKQHSFEMLEDQNGQRYKTRLSIDW
                     EMGMVELALQGDSSIVPSNRKHRIHFKGTNVSIIELPNKNDTAKFEWKDNKRTSLNDE
                     VFRLLKTASLPYELKDRLLNQFINAKNSHDLMNILHHQDKELRGRLLEMIFTSQN"
     gene            complement(12411..12887)
                     /locus_tag="VQ865_001036"
     CDS             complement(12411..12887)
                     /locus_tag="VQ865_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HET3135384.1"
                     /translation="MTSLYDFSVLNQNNQATPLDSYRGKVLLIVNTATGCGLTPQYQG
                     LQELYERYQDQGFEILDFPCNQFMGQAPGSAEEINAFCSLHFQTTFPRFAKIKVNGKE
                     ADPLYVWLKDQKSGPLGKRVEWNFAKFLIGRDGQVFERFSSKTDPKQIEEAIQTLL"
     gene            13110..16313
                     /locus_tag="VQ865_001037"
     CDS             13110..16313
                     /locus_tag="VQ865_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001193686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored hyaluronate lyase"
                     /protein_id="HET3135385.1"
                     /translation="MQTKTKKLIVSLSSLVLSGFLLNHYMTVGAEETTTNTIQQSQKE
                     VQYQQRDTKNLVENGDFGQTEDGSSSWTGSKAQGWSAWVDQKNSSADASTRVIEAKDG
                     AITISSHEKLRAALHRMVPIEVKKKYKLRFKIKTDNKVGIAKVRIIEESGKDKRLWNS
                     ATTSGTKDWQTIEADYSPTLDVDKIKLELFYETGTGTVSFKDIELVEVAAQLSEDSQT
                     DKQLEEKIDLPIGKKHVFSLADYTYKVENPDVASVKNGILEPLKGGTTNVIVSKDGKE
                     VKKIPLKILASVKDTYTDRLDDWNGIIAGNQYYDSKNEQMAKLNQELEGKVADSLSSI
                     SSQADRTYLWEKFSNYKTSANLTATYRKLEEMAKQVTNPSSRYYQDETVVRTVRDSME
                     WMHKHVYNSEKSIVGNWWDYEIGTPRAINNTLSLMKEYFSDEEIKKYTDVIEKFVPDP
                     EHFRKTTDNPFKALGGNLVDMGRVKVIAGLLRKDDQEISSTIRSIEQVFKLVDQGEGF
                     YQDGSYIDHTNVAYTGAYGNVLIDGLSQLLPVIQKTKNPIDKDKMQTMYHWIDKSFAP
                     LLVNGELMDMSRGRSISRANSEGHVAAVEVLRGIHRIADMSEGETKQRLQSLVKTIVQ
                     SDSYYDVFKNLKTYKDISLMQSLLSDAGVASVPRPSYLSAFNKMDKTAMYNAEKGFGF
                     GLSLFSSRTLNYEHMNKENKRGWYTSDGMFYLYNGDLSHYSDGYWPTVNPYKMPGTTE
                     TDAKRADSDTGKVLPSAFVGTSKLDDANATATMDFTNWNQTLTAHKSWFMLKDKIAFL
                     GSNIQNTSTDTAATTIDQRKLESSNPYKVYVNDKEASLTEQEKDYPETQSVFLESSDS
                     KKNIGYFFFKKSSISMSKALQKGAWKDINEGQSDKEVENEFLTISQAHKQNGDSYGYM
                     LIPNVGRATFNQMIKKLESSLIENNETLQSVYDAKQGVWGIVKYDDSVSTISNQFQVL
                     KRGVYTIRKEGDEYKIAYYNPETQESAPDQEVFKKLEQAAQPQVQNSKEKEKSEEEKN
                     HSDQKNLPQTGEGQSILASLGFLLLGAFYLFRRGKNN"
     gene            16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ865_001038"
                     /pseudo
     CDS             16692..17077
                     /gene="tnpA"
                     /locus_tag="VQ865_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005816675.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(17456..18085)
                     /locus_tag="VQ865_001039"
     CDS             complement(17456..18085)
                     /locus_tag="VQ865_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000167291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HET3135386.1"
                     /translation="MTKSDTIIELKKQKIVAVIRGNTKEEGLQASIACIKGGIKAIEI
                     AYTNQYAGQIIKELVDLYQDDQSVCIGAGTVLDAVTARDAILAGANYVVSPSFHAETA
                     KMCNLYSTPYIPGCITLTEITTALEAGSEIIKLFPGSTLSPAYISAVKAPIPQVSVMV
                     TGGVGLNNIPQWFAAGADAVGIGGELNKLASQGNFDRISEIAQQYITLR"
     gene            complement(18095..19096)
                     /locus_tag="VQ865_001040"
     CDS             complement(18095..19096)
                     /locus_tag="VQ865_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HET3135387.1"
                     /translation="MTKILLFGEPLIRISPLDATSIGDHVASSTYFGGSEINIACNLQ
                     ALGISTKVFTALPANEIGDRFLTFLKQHQIDTSSICRLGDRIGLYYLENGFGCRQSEV
                     FYDRKHTSISQIRPNMLDMDSLFQGISHFHFSGITVAIGQEVRAILLLLLEEAKRRGI
                     VVSMDLNLRTKMISVLEAKYEFSKFARFTDYCFGIDPLMIDDQNLEMFPRDSASLEEV
                     ENRMRLLKEAYGFKAIFHTLRSSDEQDKNVYQAYALEELFEESVQLKTAVYQRIGSGD
                     AFISGALYQLLHHSSLKTTIDFAVASATLKCTLPGDHLSTSATSIENLLANAQDIIR"
     gene            complement(19127..19768)
                     /locus_tag="VQ865_001041"
     CDS             complement(19127..19768)
                     /locus_tag="VQ865_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpiB/LacA/LacB family sugar-phosphate isomerase"
                     /protein_id="HET3135388.1"
                     /translation="MKIALINENSQASKNHIIYDSLKEATDKKDYQLFNYGMRGEEGE
                     SQLTYVQNGLMAAILLNTKAVDFVVTGCGTGVGAMLALNSFPGVVCGLAVDPTDAYLY
                     SQINGGNALSIPYAKGFGWGAELTLKLMFERLFAEEMGGGYPRERVIPEQRNARILNE
                     VKQITHNDLMTILKTIDQDFLKDTISGKYFQEYFFENCQDDEVAAYLKEVLAK"
     gene            complement(19787..20602)
                     /locus_tag="VQ865_001042"
     CDS             complement(19787..20602)
                     /locus_tag="VQ865_001042"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000185867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HET3135389.1"
                     /translation="MTNTSFSIEQFSLKGKIALITGASYGIGFAIAKSYAEAGATIVF
                     NDINQDLVNKGIKAYREVGIEAHGYVCDVTDEDGIQAMVKQIEQEIGVIDILVNNAGI
                     IRRVPMCEMSAADFRKVIDIDLNAPFIVSKAVIPSMIKKGHGKIINICSMMSELGRET
                     VSAYAAAKGGLKMLTRNIASEYGGANIQCNGIGPGYIATPQTAPLRELQEDGSRHPFD
                     QFIIAKTPAARWGNPEDLMGPAVFLASDASNFVNGHILYVDGGILAYIGKQPE"
     gene            20873..21307
                     /locus_tag="VQ865_001043"
     CDS             20873..21307
                     /locus_tag="VQ865_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3135390.1"
                     /translation="MKIVLVGHGHFATGIYSSLQLIAGNQENVEAIDFVEGMSADELK
                     QKILLAISNEEEVLILSDLLGGSPFKVSSTIMGENPAKTMNVLSGLNLAMLMEAVFAR
                     MAHSFDEVVNKSVVAAQGGVVNGKELFSTDAEEEEEDFESGI"
     gene            21319..22509
                     /locus_tag="VQ865_001044"
     CDS             21319..22509
                     /locus_tag="VQ865_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003074342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HET3135391.1"
                     /translation="MIKKVTIEKIKSPERFLEVPLLTKEEVGQAIDKVIRQLELNLDY
                     FKEDFPTPATFDNVYPIMDNTEWTNGFWTGELWLAYEYSQQDAFKNIAHKNVLSFLDR
                     VNKRVELDHHDLGFLYTPSCMAEYKINGDGEAREAALKAADKLIERYQEKGGFIQAWG
                     DLGKKEHYRLIIDCLLNIQLLFFAYQETGDQKYYDIAESHFYASANNVIRDDASSFHT
                     FYFDPETGQPFKGVTRQGYSDDSCWARGQSWGVYGIPLTYRHLKDESCFDLFKGVTNY
                     FLNRLPKDHVSYWDLIFNDGSDQSRDSSATAIAVCGIHEMLKHLPEVDADKDIYKHAM
                     HAMLRSLIEYYANDQFTPGGTSLLHGVYSWHSGKGVDEGNIWGDYYYLEALIRFYKDW
                     NLYW"
     gene            22520..23011
                     /locus_tag="VQ865_001045"
     CDS             22520..23011
                     /locus_tag="VQ865_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000178618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HET3135392.1"
                     /translation="MTMPNIIMTRIDERLIHGQGQLWVKYLGCNTVIVANDEVSTDKM
                     QQTLMKTVVPDSVAMRFFPLQKVIDIIHKANPAQTIFIVVKDVKDALTLVEGGVPIKE
                     INIGNIHNAPGKEQVTRSIFLGEEDKAALKELSQTHQVTFNTKTTPTGNDGAVQVNIM
                     DYI"
     gene            23026..23805
                     /locus_tag="VQ865_001046"
     CDS             23026..23805
                     /locus_tag="VQ865_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000026606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HET3135393.1"
                     /translation="MSINVFQAILIGLWTAFCFSGMLLGIYTNRCIVLSFGVGIILGD
                     LPTALAMGAIGELAYMGFGVGAGGTVPPNPIGPGIFGTLMAITSAGKVSPEAALALST
                     PIAVAIQFLQTFAYTVRAGAPETAMKHLKNHNLKKFKFTLNATIWLFAFIGFTLGCLG
                     ALSMDTLLKLVDYIPPVLLTGLTVAGKMLPAIGFAMILSVMAKKELIPFVLLGYVCAA
                     YLNIPTIGIAIVGTIFALIEFYNKPKTADHVVEEEAHDDWI"
     gene            23792..24610
                     /locus_tag="VQ865_001047"
     CDS             23792..24610
                     /locus_tag="VQ865_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3135394.1"
                     /translation="MTGSNKLTKRDYLKTSLRAFFCQNGFNYSNYQGLGYANVMYPAL
                     KKHYGEDQEGFYQALEENCEFYNTNPHFLPFITSLHLVMLENGRPAKETRSIKMALMG
                     PLAGIGDSLSQFCLAPLFSTIAASFAQEGLVVGPILFFLAMNTILTAIKLSTGLYGYK
                     LGTTVIDKLSEQMATISRIANIIGVTVIAGLAATSVKIMVPITFAAGEVKADAKQSIV
                     SIQGMLDKVAPALLPALFTLLVYYLIKEKKWTTYKLVILTVIIGIIGSWLKIIA"
     gene            24610..24903
                     /locus_tag="VQ865_001048"
     CDS             24610..24903
                     /locus_tag="VQ865_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HET3135395.1"
                     /translation="MDTTLFYGIVIVLAVSPLLLSSFHSIRQQKLLRKQMEQRQEYLA
                     SLTSGDEVLLLSGIHGKIISIKDDLVSLQIAKGVVIYVEKESVMGKTKELLFK"
     gene            24925..26826
                     /locus_tag="VQ865_001049"
     CDS             24925..26826
                     /locus_tag="VQ865_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000657070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alginate lyase family protein"
                     /protein_id="HET3135396.1"
                     /translation="MKEERRQFFERVDGNQCRDYILSHCSKDYEKVKSSLERLMDNRF
                     MFDSPWDMEPCSKIHQIQPMVWDQVFEDDPEWSYMLNRQEYLLQFMIGYLVEGDKDYI
                     QKCKFFLFDWIEQVREFSPQSLMTRTLDTGIRSFTWLKLLLLLLKFDLLEEKELEKIL
                     VSLEKQIDFMKSYYRAKYTLSNWGILQTIPMLAIYHFFSDKMDLEEAYHFASEELKQQ
                     IETQILGDGSQFEQSILYHVEVYKALLDLCLLLPDLQDSYQELLEKMATYIQMMTGLD
                     GRTLAFGDSDSTETTEMLSLSAVVLNKEDLLNGLDVKVDLLSLLFLGREKVKRLQEFE
                     RRAWQPKSMIFEDSGHVCIKDEHRYLFFKNGPLGSAHSHSDENSFCLQYQGQPIFIDA
                     GRYSYREIYERYLLKSAWSHSTCIVDGKAPERITGSWEYEYYPHSLFCHHKEREGVHY
                     IEGAYWSAEPDLPYLHKRKILMLVEDVWLLVDDIRCQGQHEALIQFILDKDVTYQDGK
                     INQLRLWSEVDFDLEDTIISPKYNELERSSKLTKRQFFENQMLDYTIIAHESFEIIRH
                     SVYQTDDREVENALAFEVKNDETDKLILLLSEDIGVGEKLCLVDGTKMRGKCLVYDKI
                     NERMIRLQC"
     gene            26886..27887
                     /locus_tag="VQ865_001050"
     CDS             26886..27887
                     /locus_tag="VQ865_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000412458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3135397.1"
                     /translation="MEKKLTIKDIAEMAQTSKTTVSFYLNGKYEKMSQETREKIEKVI
                     HETNYKPSIVARSLNSKRTKLIGVLIGDITNSFSNQIVKGIEDIASQNGYQVMIGNSN
                     YSQESEDRYIESMLLLGVDGFIIQPTSNFRKYSRIIDEKKKKMVFFDSQLYEHRTSWV
                     KTNNYDAVYDMTQSCIEKGYEHFLLITADTSRLSTRIERASGFVDALTDANMRHASLT
                     IEDKHTNLEQIKEFLQKEIDPDEKTLVFIPNCWALPLVFTVIKELNYNLPQVGLIGFD
                     NTEWTCFSSPSVSTLVQPSFEEGQQATKILIDQIEGRNQEERQQVLDCSVNWKESTF"
     gene            complement(27997..28332)
                     /locus_tag="VQ865_001051"
     CDS             complement(27997..28332)
                     /locus_tag="VQ865_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135398.1"
                     /translation="MKSLARLLIIHVFISIFLFFALISGAVSHTVLLLLLLFLPALNK
                     GLEKIQSKRIPVLNAALFFLLISFPQLLSNPVQWKFSIFLVVTIISSLAYFYNFYQVV
                     KEVDQKQLI"
     gene            complement(28343..28585)
                     /locus_tag="VQ865_001052"
     CDS             complement(28343..28585)
                     /locus_tag="VQ865_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135399.1"
                     /translation="MKKEKKQLRYPGLKAGSIYGTVIFFIIPLIDTLTSENPNFISSL
                     LNTKHIFKTILGAFFFGVMIHIVDSLRIARAKKDQD"
     gene            complement(28596..29138)
                     /locus_tag="VQ865_001053"
     CDS             complement(28596..29138)
                     /locus_tag="VQ865_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000712356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3278 domain-containing protein"
                     /protein_id="HET3135400.1"
                     /translation="MKKETFTEKLIKRTYGISGPLDEYKRREADSIGNQVFIILFYLM
                     IFGNLIPLLLAYKYPQKVALIYPPLILVIALIAAGYVTYQMKKTGITVIEPDMLNEKE
                     SKQLHYLGLKAGLFFGLWMFFITPLLSILIDEGQDYFHSLLTIRNGVSSILGSIFFGA
                     SIQFLISRRIAKTKKNQDED"
     gene            complement(29154..29348)
                     /locus_tag="VQ865_001054"
     CDS             complement(29154..29348)
                     /locus_tag="VQ865_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001082472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135401.1"
                     /translation="MNRVKEFRKELGISQLELAKDIGVSRQTINMIENDKYNPTLELC
                     LNLARSLQTDLNSLFWEEDF"
     gene            29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ865_001055"
     CDS             29514..30464
                     /gene="rsmH"
                     /locus_tag="VQ865_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HET3135402.1"
                     /translation="MTKEFHHVTVLLHETIDMLDVKPDGIYVDATLGGAGHSEYLLSK
                     LSEKGHLYAFDQDQNAIDNAQKRLAPYIEKGMVTFIKDNFRHLQARLREAGVQEIDGI
                     CYDLGVSSPQLDQRERGFSYKKDAPLDMRMNQDASLTAYEVVNHYDYHDLVRIFFKYG
                     EDKFSKQIARKIEQAREVKPIETTTELAEIIKLVKPAKELKKKGHPAKQIFQAIRIEV
                     NDELGAADESIQQAMDMLALDGRISVITFHSLEDRLTKQLFKEASTVEVPKGLPFIPD
                     DLKPKMELVSRKPILPSAEELEANNRSHSAKLRVARKIHK"
     gene            30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ865_001056"
     CDS             30476..30793
                     /gene="ftsL"
                     /locus_tag="VQ865_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HET3135403.1"
                     /translation="MAEKMEKTGQILQMQLKRFSRVEKAFYFSIAVTTLIVAISIIFM
                     QTKLLQVQNDLTKINAQIEEKKTELDDAKQEVNELLRAERLKEIANSHDLQLNNENIR
                     IAE"
     gene            30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ865_001057"
     CDS             30797..33049
                     /gene="pbpX"
                     /locus_tag="VQ865_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2X"
                     /protein_id="HET3135404.1"
                     /translation="MKWTKRVIRYATKNRKSPAENRRRVGKSLSLLSVFVFAIFLVNF
                     AVIIGTGTRFGTDLAKEAKKVHQTTRTVPAKRGTIYDRNGVPIAEDATSYNVYAVIDE
                     NYKSATGKILYVEKTQFNKVAEVFHKYLDMEESYVREQLSQPNLKQVSFGAKGNGITY
                     ANMMSIKKELEAAEVKGIDFTTSPNRSYPNGQFASSFIGLAQLHENEDGSKSLLGTSG
                     MESSLNSILAGTDGIITYEKDRLGNIVPGTEQVSQRTMDGKDVYTTISSPLQSFMETQ
                     MDAFQEKVKGKYMTATLVSAKTGEILATTQRPTFDADTKEGITEDFVWRDILYQSNYE
                     PGSTMKVMMLAAAIDNNTFPGGEVFNSSELKIADATIRDWDVNEGLTGGRMMTFSQGF
                     AHSSNVGMTLLEQKMGDATWLDYLNRFKFGVPTRFGLTDEYAGQLPADNIVNIAQSSF
                     GQGISVTQTQMIRAFTAIANDGVMLEPKFISAIYDPNDQTARKSQKEIVGNPVSKDAA
                     SLTRTNMVLVGTDPVYGTMYNHSTGKPTVTVPGQNVALKSGTAQIADEKNGGYLVGVT
                     DYIFSAVSMSPAENPDFILYVTVQQPEHYSGIQLGEFANPILERASAMKDSLNLQTTA
                     KALEQVSQQSPYPMPSVKDISPGDLAEELRRNLVQPIVVGTGTKIKNSSAEEGKNLAP
                     NQQVLILSDKAEEVPDMYGWTKETAETFAKWLNIELEFQGSGSTVQKQDVRANTAIKD
                     IKKITLTLGD"
     gene            33051..34031
                     /locus_tag="VQ865_001058"
     CDS             33051..34031
                     /locus_tag="VQ865_001058"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HET3135405.1"
                     /translation="MFISISAGIVTFLLTLVGIPAFIQFYRKAQITGQQMHEDVKQHQ
                     AKAGTPTMGGLVFLITSVLVAFFFALFSSQFSNNVGMILFILVLYGLVGFLDDFLKVF
                     RKINEGLNPKQKLALQLLGGIIFYLFYERGGDILSVFGYPVHLGFFYIFFALFWLVGF
                     SNAVNLTDGVDGLASISVVISLSAYGVIAYVQGQMDILLVILAMIGGLLGFFIFNHKP
                     AKVFMGDVGSLALGGMLAAISMALHQEWTLLIIGIVYVFETTSVMMQVSYFKLTGGKR
                     IFRMTPVHHHFELGGLSGKGNPWSEWKVDFFFWGVGLLASLLTLAILYLM"
BASE COUNT        10306 a         6070 c         7607 g        10141 t
ORIGIN      
        1 tcattgagta tcagtatagg ttataagaat aagtcttgta gggttttggc aaccccatct
       61 tggtcgttgg taagggaaat ttgctcatct gcataaggga gtagctctgg attggcattt
      121 ttcatggcat aacccttccc agcaaaagcg agcatttcgg tatcattgtg ttcatctcca
      181 aaggcaatca aatctttttt gtcacgattc attatcttga gcaagtagtc caaagcaaag
      241 gccttgttga caccttttgg ggtacattca aggatattga gcggacctcc ccaggtattg
      301 atagaaagtt gatgctggta gaaggcgttc atgtcttttg ccaaggcata tttgtcactg
      361 gctctggtct gcaagaggat acagttaggg tccttggtca ccaattcagg ctggaattga
      421 tcttcaggct ggaaagcttc tacaccaaat agtttgggat tggcaatttc ttcattggga
      481 tttgtaatgt agaatttttt acgatattct ccagcgataa aatcggcttg aatgtcctct
      541 gaacgttgaa ccatatctag cagatatttt ttgtctacag tcaaacactt ttcaaaatcc
      601 caaacttggt ctggtaaatg agtaagggat ccgttgaagt taatcatagg agtgtctaag
      661 cccagttcac ggtaaaaatc ttttgacata cggtaagggc gacctgtcgt aataataacc
      721 tgatggcctt tttcagcaac ttttttgatg gtttttttgg taaagtcaga aatttgactg
      781 tctgagttga gcagggttcc atccaggtca actgcaataa tttttttcgt catatggacc
      841 tttctagtgt gttttcagat aagatgtctt ctattataac agaaagcagg cagaaaagca
      901 gattccaaac aaaaaatgaa attggattaa tttcttaaac aaatcaaaca aagacattga
      961 aaaagtgaat gataaatgat ataattctat tattgttcgt aaaaattaaa aggagattga
     1021 tgatggacaa attatttaaa ctaaaagaga acggtacaga cgttcgtaca gaggttctcg
     1081 ctggtttaac aactttcttt gcaatgagct atattctctt tgtaaaccca caaatacttt
     1141 cacaaacagg aatgcctgct cagggcgtct tcctagcgac gattattggt gcagtagcgg
     1201 gtaccctgat gatggctttt tatgctaact taccttatgc ccaagcgcca ggtatgggac
     1261 tcaatgcctt ctttaccttt acagttgtat tcgggcttgg ttattcttgg caagaagccc
     1321 tagctatggt cttcatctgt gggattattt cattgattat taccttgaca aatgttcgta
     1381 aaatgatcat tgaatcgatt cccaatgctc ttcgctcagc tatttcagct ggtatcggtg
     1441 tcttccttgc ctatgtaggg attaagaatg ctggactttt gaaattcacg attgatccag
     1501 gcaactatac tgttgtagga gaaggggctg acaaagctca agcaacgatt gcagcaaact
     1561 cttcagcagt tccaggattg gtcagcttta ataatccagc tgttttagtg gctcttgcag
     1621 gacttgccat tactatcttc tttgtcatca aagggattaa agggggaatt attctctcta
     1681 tcttgacaac aactgttctt gctattgcag ttggtttggt tgatttgtct agtatcgatt
     1741 ttgctaataa ccatgttggt gcagcttttg aagatttgaa gacaatcttt ggtgcagctc
     1801 ttggttcaga aggattggga gctttggttt cagatacagc tcgcttgcct gaaactctga
     1861 tggccattct tgccttctca ttgacagata tttttgacac aattggtacc ttgatcggta
     1921 caggtgaaaa agttggtatc gtagcgacaa atggtgaaaa tcaccaatca gccaaattgg
     1981 ataaggctct ttactctgat ttgattggaa cgacagtcgg tgccattgca ggtacttcaa
     2041 acgtaacgac ttatgttgag tctgctgctg gtatcggtgc tggtggacgt actggtttga
     2101 cagccttggt tgtagctatc tgttttgcga tttcaagctt ctttagccca cttctagcga
     2161 tcgtaccaac agcggctaca gctccaatct tgattatcgt tgggattatg atgcttggta
     2221 gcttgaaaaa tatccattgg gatgatatgt ctgaagcagt tcctgccttc ttcacatcta
     2281 tctttatggg attcagctac tctatcactc aagggattgc agttggtttc ttgacttaca
     2341 ctttgactaa gcttgttaaa ggtcaagtta aagatgttca tgtcatgatt tggattttgg
     2401 atgccttgtt tatccttaac tacatcagca tggccttata atagaatgac ccagggggat
     2461 ttcccccctt ttttaataca aaggagatag gtgatgaaag agaaaaatat gtggaaagaa
     2521 ttgttgaatc gtgcaggctg gattttggtc tttttacttg ccgtcctttt atatcaggtt
     2581 cccctagtgg ttacctctat tttgacttta aaagaagtag ccctgctaca gtcagggctg
     2641 atagttactg gtatttctat tgtggttctg gtgctattta ttattggagc tcgtaaaacg
     2701 caattggcaa gttttaattt ttcttttttt agaactaagg atttggcacg tttgggcttg
     2761 agttatttag tcattatctg ttcaaatata cttggttcta tcttgttgca actgtcaaat
     2821 gagacgacaa cagctaacca gtctcagatt aacgatatgg ttcagaatag ttctctgatt
     2881 tctagcttct tcttgctagc cttgcttgct ccaatttgtg aggaaatctt gtgccgtggg
     2941 attgttccta aaaagatttt ccgaggcaag gagaacttgg gatttgtagt cggtacgatt
     3001 gtgtttgctt tattgcatca accaagtaat ttaccttctt tattgattta tggaggtatg
     3061 tcgacagttc tatcttggac ggcctacaag acccaacgtt tggaaatgtc gatcttgctt
     3121 cacatgattg ttaatgggat tgctttctgt ttgttggctc ttgtggtgat tatgagtcgg
     3181 acattaggaa tttctgttta aaagttttta tgtaggaacc gacctctttc tactgggaaa
     3241 aagatgaatg caatcgtgtc catctttttc tttttatggt aaaatagaga aataatatga
     3301 tgaaaagcct tgagggagtg accgatatgt caagtaaagc taatcatgca aagacagcta
     3361 tttgcggaat tatcaatgta accccagatt ccttttcgga tggtggtcaa ttttttgttc
     3421 ttgagcaagc gctccagcag gctcgtaaat tgatagcaga aggagccagc atgctagata
     3481 tcggcggtga atcgactcgg cctcggccgg gaagtagcta tgttgagata gaagaggaaa
     3541 tccagcgtgt tgttccagtg attaaagcga ttcgcaagga aagtgatgtc ctcatctcta
     3601 ttgatactcg gaagagtcag gtggcagagg ctgctttggc tgctggtgcc aatctagtca
     3661 atgatatcac tggtcttatg ggtgatgaga aaatggccca tgtggttgct aaggctggtg
     3721 cgaaagtagt cattatgttt aacccagtta tggctcggcc tcagcatcct agttcgctta
     3781 tcttccctca ttttggtttt ggtcaaacct ttacagaaaa agagttagct gactttgaaa
     3841 cattgccaat cgaagaaatg atggaggctt tctttgaacg agcactagcg agagcggcag
     3901 aagctggtat tgcaccagaa aatatcctgt tggatccagg aattggcttt ggtctgacca
     3961 agaaagaaaa tctgcttctt ttacgggacc tggataaact acatcagaag ggctatccaa
     4021 tctttctcgg agtgtcgcgc aagcgatttg tcatcaatat cctagaggag aatggttttg
     4081 aagtcaatcc tgagacagag cttggtttcc gaaatcggga cacggcttcg gctcatgtaa
     4141 ctagtatcgc tgcgagacag ggtgtagaag tggtgcgcgt gcatgacgta gctagtcaca
     4201 ggatggcagt tgaaattgcc tctgccattc gtctggctga tgaagcggaa aatttagatt
     4261 taaaacaata taaataagat gaaagaaatt gaaaacaatc agtggattgc taactaccgg
     4321 acggatcaac cgcattttgg cttggaacga atggtggaac tgttagcttt gcgtggcaat
     4381 ccccatctca aactcaaggt cctccatatc ggagggacta acggcaaggg ctcgactatt
     4441 gcttttttga aaaagatgct agaaaagcta gggctgagag ttggcgtgtt tagctcgccc
     4501 tatctcattc attacacaga ccagattagc atcaatgggg aatcgatctc agaagcgagg
     4561 ctagaagctc tcatggcaga ttatcagtct ttgctggagg gagaagcggt cgccaattta
     4621 cagggcacaa ccgagtttga gattatcaca gccctggcct atgactactt tgcctcagag
     4681 caagtagatg tggccatcat ggaagttggc atgggtggac ttttggatag taccaatgtc
     4741 tgtcagccca ttttgacagg aattacaact attggcttgg atcatgtggc cctacttggt
     4801 gacaccttgg aggccatagc agagcagaag gcaggtatta tcaaacaagg gatgcccttg
     4861 gtaacagggc gtattgctcc agaagccttg actgtgattg accgcattgc ggaagggaaa
     4921 gatgcgccga gacttgccta cgggacagat tatcaggttc gtcatcaaga aagtgtggtg
     4981 acaggggaag tctttgacta tacaagtgct gtcagacaag gtcgcttcca gactagcctg
     5041 cttggtttgt accaaataga gaatgctggg atggccatag ctttacttga tactttttgt
     5101 caagaagatg gtcgagagct agcaagcaat gactttcttg gtcaagcctt ggaagaaaca
     5161 agttggccag ggcgtttgga aatcgtgtca agagatccct tgatgatttt ggatggagcc
     5221 cacaatcccc atgctatcaa ggccttgttg gtaaccttgc aagaacgttt tgcagattat
     5281 cataaggaaa tcctcttcac ttgtatcaaa accaaggcct tggaggatat gttggccttg
     5341 ttgggagcca tgccagatac cgagcttact ctaacacatt ttgcggatag tcgggcgacg
     5401 gatgaaagcg tgctgaaaga ggcagctaag tctagaaatc tcagctacca agattggcat
     5461 gattttctag atcagaattt gacagataaa aaagaagaga aacaaacagt taggattgtc
     5521 acaggttcct tgtatttctt gagccaagtg agggcctatc tgatggagag gaagaacgag
     5581 aatggataca caaaagattg aagcagctgt aaaaatgatt atcgaggctg taggagagaa
     5641 cgctaatcgc gagggcttgc aggaaacacc tgctcgtgta gcccgtatgt atcaagagat
     5701 tttttcaggt cttggtcaaa cagcagagga acatttgtca aaatcctttg aaattattga
     5761 cgataatatg gtggtagaaa aggatatctt tttccatacc atgtgtgaac accacttctt
     5821 gccattttat ggtagagcgc acattgccta cattccagat ggtcgtgtgg caggcttgtc
     5881 taagctagcc cgtacggttg aagtttattc gaaaaaacca caaattcaag aacgtttgaa
     5941 tatcgaagtg gccgatgcct tgatggacta tctaggtgct aaaggagcct ttgttgtcat
     6001 tgaggcggaa catatgtgta tgagtatgcg tggtgttaga aaaccaggca ctgcaacctt
     6061 gacgacagta gctcgtggtt tatttgaaac agataaggac ctccgcgacc aagcttatcg
     6121 tttaatgggg ctataaaaag aatccgcttc aagcggattt ttctagaaag gaatcattat
     6181 ggatcaactg cagattaagg atttggaaat gtttgcctat catggtcttt ttcctagtga
     6241 gaaagaattg gggcagaaat ttgtcgtttc agccatccta tcctatgata tgaccaaggc
     6301 agctacagac ttggatttaa cagcctctgt ccattacgga gaattgtgtc agcagtggac
     6361 gacttggttt caggaaacga gtgaggattt gattgaaacg gtagcctata aactggtgga
     6421 acgtaccttt gagtcttatc ctcttgtcca agaaatgaag ttggaactga aaaaaccttg
     6481 ggcaccggtg catttgtcac tagatacttg ctcggtaacc attcatcgcc gcaagcaacg
     6541 agcctttatc gccctaggaa gcaatatggg agataagcaa gcaaacttga agcaagccat
     6601 tgacaaactg cgagctcgtg gcatccatat tctcaaagag tccagtgtct tagcgacgga
     6661 gccttggggt ggagtggagc aggatagctt tgccaatcaa gtggttgagg tggaaacctg
     6721 gctaccagca caagacttgt tagaaacctt gttagccatt gagtcagagc tgggacgggt
     6781 gagagaagtg cattggggac ctcgtttgat tgatttggac ttgctctttg tggaggacca
     6841 gatcctttat acagacgacc tcatattgcc tcatccttac atagcggaac gcctttttgt
     6901 ccttgagtcc ttacaggaaa ttgcgcctca ttttatccat ccgatattaa aacaaccgat
     6961 ccgcaacttg tatgatgctt tgaaaaaata gaaaaactct agttttcagt tacttgcaac
     7021 tgaaggctag agtttttaaa ataggtcatt ttcttctggg aggaggatag tttctctacc
     7081 gtccatgtct aaaaccagta ctcttggggg ataacgaggg tcgaaaggat ggttaaagtc
     7141 aaaatcaatg gctgtaggga ggtgttgact tgaaaagtgg aaggtaatct ttccttggtt
     7201 attaagcaat tgaaactcga gttcttcttc caattcaaag acatttttta agaaatgatc
     7261 gatgatatac caaaaagagt caatgatgtc atcaggcaag ctggtaacaa tgccaaaact
     7321 agcagaccgc atgtgggtat tggtaaaagc catatctctg tcccctttct tttcccttat
     7381 catacagcaa ataggattaa aaatcaagaa aaggtgattt tttgaaaagg attttaacta
     7441 cagggaaaaa gaaggaaaaa aattcccaaa aatctaccga agttaatagg taaattccca
     7501 aattaacttg attatataac tttcagttac tttgagaagt taccgaaaaa tatttttcat
     7561 atctattgac ttttaggggt gaaatttggt atgatagtag gcggtattgt ttaccccatt
     7621 tgaaaggccc cggaaccttc caaatacttt tcgatgggaa ggaacaccca tcaccgtaaa
     7681 caaaaatcga actatatata ggagaaatca tgaacaaaac aacatttatg gctaaaccag
     7741 gccaagttga acgtaaatgg tacgtagttg acgcaactga tgtaccactt ggacgtcttt
     7801 ctgcagtagt tgctagcgta cttcgcggaa aaaacaaacc aacatttaca ccacacactg
     7861 atacaggtga cttcgtgatt gttatcaatg ctgaaaaagt taaattgact ggtaaaaaag
     7921 caactgataa aatctactac actcactcaa accacccagg tggattgaaa caaatctctg
     7981 caggtgaact tcgttctaaa aatgcagtac gtttgattga gaaatcagtt aaaggtatgc
     8041 ttccacacaa tacacttgga cgcgctcaag gtatgaagtt gaaagtattt gttggagctg
     8101 agcacactca cgctgcacaa caaccagaag ttcttgacat ttcaggactt atctaaggaa
     8161 aggaacaata aagtatgtca caagcacaat atgcaggtac tggacgtcgt aaaaacgctg
     8221 ttgcacgcgt tcgccttgtt ccaggaactg gtaaaatcac tgttaacaaa aaagatgttg
     8281 aagagtacat cccacacgct gaccttcgtc ttgtcatcaa ccaaccattc gcagttactt
     8341 caactgtagg ttcatacgac gttttcgtta acgttatagg tggtggatac gctggtcaat
     8401 caggagctat ccgtcacggt atcgctcgtg cccttcttca agtagaccca gacttccgcg
     8461 attcattgaa acgcgcagga cttcttacac gtgactcacg taaagttgaa cgtaagaaac
     8521 caggtcttaa gaaagctcgt aaagcatcac aatttagtaa acgttaattc gaaagaatta
     8581 ctatacttat acagagcacc tttcggggtg ttcttttttt atactttctt actaaattgg
     8641 tgcaattgac acagttgttg cgactttagt cgcttacaaa tgtggctgca acctgacaag
     8701 gtcagttgcc tcaaaacgtt aatcaataca attatatcaa cgtttcaaag cactcaagag
     8761 tttacctcat gggtgctttt tttatgtttt ttgaaaaagt tcacctcaaa gtttacctta
     8821 ttttcacctt attgttttag agactgtaag gcaaattcac cgacggccat agggactaca
     8881 ttagaagtat tgacataaat ctgtgttgta cctgtgtcgc tatgtattag agcttcagaa
     8941 atggcttcta agctcattcc tgcttgttta gcgagcgttg ctccggtatg acgtagtttg
     9001 tgtggcgtag cgtgtgtaag ctctgggtgt cgttttctga tagttttcat cttattattg
     9061 agatagtcag aatgtaaagg tttattgata ttgcctttgg tatctatgta agtaaagatg
     9121 aattgttctg gattactgat gataccaaac tttgccagtt catatttttg ttgttttttc
     9181 catgaagtca gaagttgaag taagtcatta gaaatagaga aaatgggaaa tgtttccaca
     9241 ataaaacgca tattatcaga tggttaatgc gttttatatt tgggtttgag gcttataaaa
     9301 taggataagc gtactgaaaa cttagatatg acaaacaaaa taaaattttt aaaagctaca
     9361 gagaaacatg gtataatgta tctaaaggag gtagcatatg tccttagata tagataaaga
     9421 aaagatgaca atcatgggaa tagcttttga aaaccgatcc gtttttaaga gtgtttggta
     9481 tgctttaagt acaaatatga ttgaaggatg gcgacctacg gttagtgatg ttgaaaaatt
     9541 acgagatgaa gctcttgctc tggggatgac ttaatgaagc gcaactgtta tgaatcttat
     9601 gactatgttg atccggataa tttatatacc gatccgggtt cttcagttct aagaaataag
     9661 caggaaggaa aaaagcacgc gagcttgaat atcgtatgat tgctagtaag agtttgaaat
     9721 tatttatcaa tcctatctta gttaatagtt taaaagtagt ttgtttcaca actgcataag
     9781 cttagaaaag ttgaaaagtg ataactcttt aataaactct tggtttgtta aaagatattt
     9841 tgtccactac atttttttca attgactatt atttgtcata gatataacag atagaacatt
     9901 gcattcagaa taatgaaaaa cgcatcaaaa atggtgcgtt ctgtttttat gctaccataa
     9961 aaggaggaaa acaaattgaa aatttttaag ggagagtttt atcgaatctc tgtattaaca
    10021 gacaagctag taaggttaga atactctcga actggaaatt ttgaggatag aacgacacaa
    10081 cttatctata atagagattt tggccaagtt tcgttagatt atatcgagac atcaaatgta
    10141 ctagatatta tgacggacta ttttcatctg cactttaata aaggagaatt taacgccgaa
    10201 aatttattta tagaattaaa aggaaatttt gccgtatatg gtagtcgctg gtattttggt
    10261 gaatctattg aaacgttaaa aggaacagct cggactctgg ataaggcaga tggagcaatc
    10321 tcgttagaag atggaattat tagccgaaat ggtatagcct tattggatga ttctcaagga
    10381 tttatttggg atgaacaatc tggttatatt gagagagaaa atcaaattga cctgtatttc
    10441 tttgcctatg ggcatgatta tagaggagca atcagagact tttaccattt gactggttca
    10501 acacccttgt tgccaagata tgctttaggc aattggtgga gtagatattg gccttatacg
    10561 tcggatgaat acttggattt aatagacaga tttgaaacag agaaaattcc attatctatc
    10621 ggtgtgttag atatggattg gcatataact gacattccag ctcgttttgg aagtggctgg
    10681 acaggatata gttggaatag aaacttaata ccaaatccag aacagttatt gcaacaactt
    10741 catgatagaa agttaaaact ctccttaaat gtccatcctg ctgatgggat acgggcttat
    10801 gaagaagctt atcctcaaat cgcaaaacgg ttggggttaa atgtagaact agaagaacct
    10861 gctatttttg atttttttaa tccctctttt agggaagcct actttaaaga tgttcattat
    10921 gagctagaaa agcagggagt agatttttgg tggattgact ggcaacaagg gacacaaggt
    10981 atgctagatc cactttggct tttaaaccat tatcactatc aggatagttg taaaaatgca
    11041 gaaggtggtt tgattttatc aagatatgca ggtcctggta gtcaccgcta ccctgttggt
    11101 ttttcagggg acactattat tagttggaat tccttaagat ttcaacccta ttttacagcg
    11161 acagcatcta atatcggtta tagttggtgg agtcatgata tcggtggaca tatgttgggg
    11221 gattatgacg aagagctaca aactagatgg ctacagtttg gtgtttttag tccgattact
    11281 cgattacata gttctagaag tccttttaat agtaaagaac cttggttctt ttcagaaaca
    11341 acatctaaga ttatgaagaa ataccttcgt ttgagacatc agatgattcc ctatctatat
    11401 accatgaatg taaagacaca tgaggaaggt gccccattaa tcagtccaat ctattatttc
    11461 tatccagaga atgatgagag ctataatgtt ccaaaccaat acttttttgg aacagaactg
    11521 atggtggctc ccattgtaga aaagatggat ttgacattcc aatctgcaaa agtagatgta
    11581 tggttccctg aaggtgaatg gtatgacttc ttttcagaga aaaaatacac aggtggtgtg
    11641 aagttaagtg tttataggga catctcgact acgcctgtgt ttgcaaaaag tggtgcaatc
    11701 attcccttgg ttggttctga gataggtatg ggtgttgatt tacctgaggt tgtagattgg
    11761 tatgtattcc cagggaaaca acattctttt gaaatgcttg aagatcaaaa tggtcaaaga
    11821 tataaaacaa gattatcaat cgattgggaa atgggaatgg tagagttagc attacaagga
    11881 gattctagta tcgttccaag caatagaaaa catagaattc attttaaagg aacgaatgtg
    11941 tctataattg aattgccaaa taagaatgat acagctaaat ttgaatggaa agataataaa
    12001 aggacatctt taaatgacga agtttttaga ctactaaaga cagcttctct tccatatgaa
    12061 ttaaaagata gattgttaaa tcaattcatc aatgccaaaa actctcatga cttaatgaat
    12121 atcttgcatc atcaggataa ggaattgaga gggcgtttgt tggaaatgat atttactagc
    12181 caaaactaat tgaaataatt agaaagtcat ttgtttagtg tatatgaaga ttctgtatgg
    12241 tattcgttat cactggtcac attgaaattg tgaaataagc acctacaaca tagactttac
    12301 aacacttcat gtttcatatc atggggtgtt tttctattta agtcaaagcc aatcaaaaaa
    12361 tctcactatt catcaggtta aaggaaacct aatcatagtg agattgtgaa ttatagtaga
    12421 gtttgtatcg cctcttcaat ttgttttggg tctgtttttg aagaaaagcg ttcaaagact
    12481 tgcccatctc gaccgatgag aaacttagcg aaattccatt cgactcgttt tcctagtggg
    12541 ccagatttct ggtcttttaa ccagacatag agagggtctg cttccttacc gttgacctta
    12601 atcttggcaa aacgtgggaa ggtggtttga aaatgtaggc tacagaaggc gttgatttcc
    12661 tctgcgctgc cgggtgcttg tcccataaac tgattgcaag ggaaatccaa tatttcgaag
    12721 ccctgatctt gatagcgttc atagagttct tgaagtccct ggtactgggg cgttaaacca
    12781 catccagtag cagtgttgac aatcaagaga actttgccac gatagctatc caagggagtt
    12841 gcttggttgt tttggttcaa aacggaaaaa tcataaagtg aagtcatgag ggcctctttt
    12901 ctttttctac attgtaacag tttttacttt tttcgtcgag tcggatggaa gatattgttg
    12961 aagaataagc cctcaatatg atagaaatcg tttacaaata actttaaaaa tggtatgatt
    13021 taactaaacc ggtttactta gttgctataa atctctaatt tgagatttag ttcctattga
    13081 ttttacaata tgtttattgg agtgtataca tgcaaacaaa aacaaagaag ctcattgtga
    13141 gtttgtcttc acttgtttta tcaggatttt tattaaacca ttatatgaca gttggagcgg
    13201 aagaaacgac tacgaatacc attcagcaaa gccagaagga agttcagtat cagcaaaggg
    13261 atacaaaaaa tttagttgaa aatggtgatt ttggtcagac ggaggacgga agcagttcgt
    13321 ggacaggaag caaagctcag gggtggtcag cttgggtaga ccagaagaat agttctgcag
    13381 atgcctcaac tcgagtcatt gaggctaagg atggggctat cactatctca agccatgaga
    13441 aattaagggc agcgcttcac cgtatggttc ctattgaagt taagaaaaag tataaactgc
    13501 gtttcaagat taaaacagat aataaagtcg ggattgccaa agttcgtatc attgaggaaa
    13561 gtggtaagga caagcgattg tggaattctg caacgacgtc aggaacaaag gactggcaga
    13621 ccattgaagc agactatagc ccgactttag atgttgataa aatcaagctg gagttattct
    13681 atgaaacagg aactgggact gtttccttta aggatattga gctggtagag gtagcagccc
    13741 agctttctga ggattctcaa acagataaac agcttgagga aaagattgat ttaccaattg
    13801 gaaaaaaaca tgttttttct cttgcggact atacttataa ggtagaaaat cctgacgttg
    13861 cttcagtcaa aaatggaatt ttagaacctc ttaagggagg gacaaccaat gtcattgtca
    13921 gtaaagatgg caaggaagtg aaaaagattc ctttgaagat tctagcctct gttaaggata
    13981 catacacaga ccgtttggat gactggaatg gcatcattgc tgggaatcaa tactatgatt
    14041 ctaaaaatga acagatggcc aaattaaacc aggaattgga aggaaaggta gctgatagcc
    14101 tatccagtat ttcaagtcag gcggaccgca cctatttgtg ggaaaaattt tcaaattata
    14161 aaacgtctgc aaatctgact gccacttatc ggaaattgga ggagatggcc aagcaagtga
    14221 ccaatccttc ttctcgttat tatcaagatg aaactgtcgt tcgaacagtc agggattcca
    14281 tggaatggat gcataaacat gtctacaata gtgaaaagag cattgttggg aactggtggg
    14341 attatgaaat cggtacacct cgtgccatca acaatacctt gtctctgatg aaagaatact
    14401 tctctgatga ggaaattaaa aaatatacag atgtgattga aaaatttgta ccagatcccg
    14461 aacatttccg aaagacgact gataacccat ttaaggctct aggtggaaac ttagttgata
    14521 tgggaagagt aaaagtaata gctggtttac tgcgtaagga tgatcaagaa atttcttcta
    14581 ccattcgctc gattgagcaa gtgttcaagt tggtagacca aggtgaaggt ttttatcaag
    14641 atggatccta tatcgaccac accaatgttg cctatacggg tgcttatggg aatgttttga
    14701 ttgatggcct gtctcaactg ttgccagtca ttcaaaagac caagaatcca atcgataaag
    14761 ataaaatgca aaccatgtac cactggattg ataaatcgtt tgctcctttg ctggtgaatg
    14821 gagagctgat ggatatgagt cgtggacgct cgatcagtcg tgcaaatagc gaggggcacg
    14881 tggccgcagt agaagtacta agagggattc accgaatagc ggatatgtct gaaggagaaa
    14941 ccaaacaacg tttgcagagt cttgtgaaga ccattgttca atcggatagt tattatgatg
    15001 tctttaagaa tttgaagact tataaggata tcagtttgat gcaatccttg ttaagtgatg
    15061 caggagtcgc aagtgttcca agaccaagtt acctatctgc ctttaacaag atggataaaa
    15121 cagccatgta caatgcagag aaagggtttg gatttggctt gtcactcttt tccagtcgta
    15181 ccttgaatta cgaacacatg aacaaggaaa ataaacgtgg ttggtatacg agtgatggga
    15241 tgttctatct ttacaatggc gatttgagtc actatagcga tggctactgg ccaacagtta
    15301 atccatataa gatgcctggt acaacagaga cggatgctaa gagagcggat agcgatacag
    15361 gtaaagtttt accgtctgct ttcgttggaa cgagcaaact agatgatgcc aatgcgacag
    15421 caaccatgga tttcaccaac tggaatcaaa cattgactgc tcataagagc tggtttatgc
    15481 tgaaggataa gatcgccttt ttaggaagca atatccaaaa cacttcaaca gatactgctg
    15541 caactacaat tgaccagaga aaactggaat caagtaatcc atataaagtc tatgtcaatg
    15601 ataaagaagc ctcccttaca gaacaagaaa aggattatcc tgaaacccaa agtgtctttt
    15661 tagaatcgtc cgattcgaaa aagaatattg gttacttttt ctttaagaag agttcaatca
    15721 gtatgagtaa ggctttgcaa aagggagcct ggaaggatat caatgaagga cagtcagaca
    15781 aggaagttga aaatgaattt cttacgatta gtcaggctca taagcaaaat ggagattctt
    15841 atggctatat gctcatccct aacgtgggtc gtgccacctt caatcaaatg ataaaaaagt
    15901 tagaaagtag cctcatcgaa aataacgaaa cccttcagtc tgtttatgat gccaaacaag
    15961 gagtttgggg cattgtgaaa tatgatgatt ctgtctctac tatttccaac caattccaag
    16021 ttttgaaacg tggagtctat accattcgaa aagaagggga tgaatataag attgcctact
    16081 ataatcctga aacccaggaa tcagctccag atcaggaagt ctttaaaaag ctagagcaag
    16141 cagctcagcc acaagtacag aattcaaaag aaaaggaaaa atctgaagag gaaaagaacc
    16201 attcggatca aaagaatctc cctcagacag gagaaggtca gtcaatcttg gcaagtctag
    16261 ggttcttgct acttggggca ttttatctat tccgtagagg aaagaacaac taatttgttc
    16321 atcatctaga tgaattacat gaaactgtgg aaaatagaaa aaatccgaag aaggccaaat
    16381 atcttcggat ttttctttta aaaaagataa gttgatactt atctttttta cttcattatg
    16441 tgactatagc gttttgaaac tagaatagga cgttataact actaaaagat ttctataaat
    16501 tcatttgatt ttcctaatca atttgttcgt atcctatttc actccactat attagtccgt
    16561 ctcgctccgt gaggtgcgag acaaaacaac cacccgctat gcgggtgcgc gtcgaaggtt
    16621 ataccaaaaa aactctaaac gcgatacaat aaaggtgttc aatccaattg taaagcgaaa
    16681 ggagaaaaaa tatggcacaa aaggctcata gtttatctca cacaaagtgg aggtgttcta
    16741 tcacattgtg ttcaccccta agtatagacg aaaagtcatc tataatcaat atagaagtag
    16801 tttaggcgaa atatttcatc gcttgtgtag ttataaaggt gttgaaatga tcgagggtca
    16861 cttaatgcca gaccatgtac acatgttagt cagtattccg tcgaggctaa gtgtttcaag
    16921 ttttatgggg tatttaaaag gcaaaagtgc actcatgatg tttgacaaac acgccaatct
    16981 caagtacaag tttgggaatc ggcatttctg ggcggaaggt tattatgtaa gtccagtagg
    17041 gcttaatgaa gccacactta agaaatatag tcaagattaa agaaattatc cagtggatga
    17101 tttcttcacg agtatgaaaa tttgagaact agtaaagtat gatatatagt aaaatgaaat
    17161 aagaacagga caaaatcgat caggacagtc aaatcgattt ttaacaatgt tttagaagta
    17221 gaggtgtact attccagttt caatctacta tagcactaga taaattgagt gtaaaagaat
    17281 atgaggatcc ctttagggat agtggtaagt aataccaaag tatcttaaag aggcaagtga
    17341 cgagtcaaga gcaataaggc ttgaacaacg tgaaagccag cgtctttagg cgctggctgg
    17401 taatttgagc ttatagctct gggataaacc acccgtttga cgggtggtta tgattttatc
    17461 tgagtgtaat atactgttgg gcaatctcgc tgatgcggtc aaagttgcct tgggaagcga
    17521 gtttattgag ttcgccacca attccaacgg catctgcacc agcagcgaac cattgaggga
    17581 tgttgtttag gccgactcct ccggttacca ttacggaaac ttgtgggatc ggtgccttga
    17641 ctgcagagat atatgctgga ctgagagtac tacctgggaa gagtttgatg atttcactac
    17701 cggcttcaag tgcagtcgtg atctctgtga gggtaataca gcctggaatg tacggtgtgc
    17761 tgtagagatt gcacattttc gcagtttcag catggaaaga tggagaaaca acgtaatttg
    17821 ctccggctag aatggcatct ctagcagtta cggcatcaag cacagtacct gcaccgatac
    17881 aaacactctg atcgtcctga tacaagtcta caagttcctt gatgatttgc cctgcatact
    17941 gattggtata ggcgatttca atagctttga taccgccctt gatacaagca atcgaggctt
    18001 gcagtccttc ttcctttgta tttcctcgaa tgacagcgac aattttctgt ttttttagtt
    18061 caataatcgt atctgatttg gtcatgtaat tctcctaacg aatgatatct tgtgcatttg
    18121 ccagtaaatt ttcaatacta gttgcggaag tggagagatg gtctcctgga agagtgcatt
    18181 tgagagttgc gctcgcaact gcaaagtcaa tggtagtttt tagggaggaa tgatggagta
    18241 gttggtaaag ggcaccagat ataaaggcat ccccgctacc aattcgttga tagactgcag
    18301 tttttagttg gacagactct tcaaatagtt cttctagagc ataggcttga tagacatttt
    18361 tgtcttgctc atcactagag cggagggtat ggaaaatggc cttgaaacca taggcttctt
    18421 ttaaaagtcg catgcgattt tccacctctt ctaggctagc actgtctctt ggaaacatct
    18481 ctagattttg gtcatcaatc atgagaggat caataccgaa gcaatagtca gtaaaacgtg
    18541 caaacttaga aaattcatac ttggcttcta ggactgaaat catctttgtt ctcagattga
    18601 gatccattga aacgacaatt cctcggcgct tggcttcttc caagagtagg agaaggatcg
    18661 cacggacctc ttgaccgata gctacggtga ttccactaaa atgaaaatgg ctaatcccct
    18721 gaaagagaga atccatatct agcatgtttg gccgaatctg gctgatactc gtatgcttac
    18781 gatcgtagaa aacttcactt tgacgacaac caaagccgtt ctccaaatag tagaggccga
    18841 ttcgatcgcc aagccgacag attgaactgg tatcgatttg gtgctgtttc aagaatgtga
    18901 gaaaacgatc tccaatctcg ttggcaggga gtgcggtaaa gactttcgtt gagataccca
    18961 gggcttgcaa attacaagcg atgttaattt ctgatccgcc aaaataagtc gaactggcaa
    19021 catgatcgcc gatactggtg gcatctaatg gtgagattcg aattaatggt tcgccaaaca
    19081 gtaatatttt cgtcatccat tagttccttt ctggtttaga atagctttac ttagctaata
    19141 cttctttcaa ataagcagcg acttcatcat cttggcagtt ttcaaagaag tattcttgga
    19201 agtatttgcc agagatggtg tctttgagga agtcttggtc gattgtttta aggatggtca
    19261 tcaaatcatt gtgggtgatt tgtttcacct cgtttaagat acgagcgttg cgttgttcag
    19321 ggattacacg ttctcttggg tagccaccgc ccatttcttc agcaaataag cgttcaaaca
    19381 tcaatttgag ggtcagttct gccccccagc caaatccttt ggcataaggg atagacaagg
    19441 cgttaccacc attgatttga gaataaaggt aagcgtcagt tgggtccact gctagaccac
    19501 agacaacacc agggaagctg tttaaagcaa gcatagcccc tacacccgta ccacagccgg
    19561 taacaacaaa gtcaactgcc tttgtattta aaaggatggc agccattagt ccgttctgca
    19621 cataagttaa ttgactttct ccttcttctc cacgcatacc atagttaaat aattggtagt
    19681 cttttttatc tgtcgcttct tttagactat cgtaaataat gtgattcttg ctagcttgac
    19741 tattttcatt gattaatgcg attttcataa gatcttcttt ctatttttac tcaggttgtt
    19801 ttccgatgta ggctaagata ccgccatcta catataggat gtggccattg acaaaattgc
    19861 tggcatcact agcgagaaag acagcagggc ccatcaaatc ttcaggattt ccccaacgtg
    19921 cagcaggtgt ttttgcaatg atgaactggt caaatgggtg gcgagaacca tcttcttgca
    19981 actcacgaag aggtgctgtt tgaggagtgg caatataacc cggtccaatt ccgttacatt
    20041 ggatattggc tccaccgtat tcagacgcaa tgttgcgggt caacattttc aagccccctt
    20101 tagcagcagc ataagcgcta actgtttcac gtcccagttc gctcatcatc gaacaaatat
    20161 tgataatctt tccatgccct ttctttatca tagaaggaat aactgccttt gaaacgataa
    20221 atggtgcgtt taagtcaata tcgatgacct tacggaaatc agcggcgctc atttcgcaca
    20281 ttggaactcg gcggataata ccagcgttat taacgaggat gtcaatgaca ccaatctctt
    20341 gttcgatttg cttgaccatg gcttggatac cgtcctcgtc tgtcacgtca cagacatatc
    20401 catgggcttc gatgccaact tcacgataag ctttaatccc tttattgacc agatcttgat
    20461 tgatatcgtt aaagacaata gtagcgccgg cttcagcgta ggatttggca atagcaaatc
    20521 caattccata agaagcgccg gtgatgaggg caatttttcc ttttaaagaa aactgctcaa
    20581 ttgagaatga tgtatttgtc atttgatact tcctttcaaa tttgttaaga cttctctata
    20641 accaaattat attctagtaa accggttttg tcaataaata aatattttta tttataaaaa
    20701 gatttatttt ccttaaaaat ggaatatttt gaaatttctg tctattaaaa tgattaaaaa
    20761 gataatgaaa gcgctaatat ttttttaaaa aaactattga caagataaaa ataaaggatt
    20821 acaatgggga atataaagta aaccggtaaa cctaaacaag aaaggagaaa agatgaaaat
    20881 tgtacttgta gggcatggac attttgctac agggatttat agttctttac aattgattgc
    20941 aggcaatcaa gaaaatgtgg aggcaattga ctttgtggaa ggaatgtcag cagatgaact
    21001 caagcaaaaa atcttacttg caatttcaaa tgaagaagaa gttttaatcc taagtgatct
    21061 cttgggagga tcgccattca aggtttcttc taccataatg ggagaaaatc cagccaaaac
    21121 aatgaatgtt ctctcgggtt tgaacttagc catgttaatg gaagcagtct ttgctagaat
    21181 ggctcatagc tttgatgagg ttgttaataa atcagtagtg gcggcccagg gcggagtcgt
    21241 aaatggtaaa gaattgtttt caacggatgc agaggaagag gaagaagatt tcgaatcggg
    21301 tatttaaagg gtaaaagaat gataaaaaag gttacgattg aaaaaataaa atcgcctgag
    21361 cgcttcttag aagtaccact tctgacgaaa gaagaagtcg gccaggcaat cgataaggtt
    21421 attcggcagt tagaactcaa ccttgactat ttcaaggaag atttcccgac gccagctacc
    21481 tttgataatg tctatccaat catggataac acggaatgga ccaatggttt ctggacagga
    21541 gaactgtggt tggcttatga atacagtcaa caggatgcat ttaaaaacat cgctcataaa
    21601 aatgttcttt ctttcctgga tcgtgtcaat aagagagtag aattggatca ccatgatctc
    21661 ggcttcttgt acacaccgtc ttgtatggct gaatataaga taaatggaga tggagaggct
    21721 agagaagcag ccttgaaagc tgcagataag ttgattgaac gctatcaaga aaaaggtggt
    21781 tttattcaag cttggggaga cttgggcaag aaagagcatt accgtttgat tatcgactgc
    21841 ttgctcaata tccaactctt attctttgct tatcaagaaa caggcgatca aaaatactac
    21901 gatattgcag aaagccattt ctatgcttca gctaataatg taatccgtga tgacgcttcg
    21961 tccttccaca ccttctattt tgatcctgag acaggtcaac cctttaaagg tgtaacgaga
    22021 caagggtata gtgatgattc atgctgggca cgtggtcaat catggggagt ctatggtatt
    22081 cctttgactt atcgtcactt aaaagacgag tcctgctttg acttgtttaa gggtgtgacc
    22141 aattatttct tgaatcgtct gccaaaagat catgtgtctt attgggattt gatttttaat
    22201 gatggtagtg atcaatcacg agattcttca gcaacagcta tcgccgtctg tgggattcat
    22261 gaaatgctaa aacatctccc agaggtggat gctgacaaag atatttataa acatgctatg
    22321 catgccatgc ttcgttcctt gatcgaatat tatgcaaatg atcaatttac ccctggtggg
    22381 acaagtctcc tccacggtgt gtactcatgg cattcaggta aaggagtgga tgaaggcaat
    22441 atctggggtg actactatta cctagaagcc cttatccgtt tctacaaaga ctggaaccta
    22501 tattggtagg aggagaaata tgacaatgcc aaatattatt atgacccgta tcgatgaacg
    22561 gttgattcat ggacaaggac aactttgggt aaaataccta ggttgtaata cggtcattgt
    22621 tgccaatgac gaagtaagca cggacaagat gcaacaaact ctgatgaaaa cagttgtgcc
    22681 agactcagtt gccatgcgtt tcttcccttt gcaaaaggtg attgatatca ttcacaaggc
    22741 taatcctgct caaacgatct ttatcgttgt aaaggatgta aaggacgctt taaccttggt
    22801 agaaggtggt gtccctatca aagaaatcaa tattgggaac attcacaatg cccctggtaa
    22861 agagcaagtg acacgctcca tcttcctggg tgaagaggac aaggcagccc tcaaggaatt
    22921 aagccaaact catcaagtaa catttaatac gaaaacaact ccaacaggaa atgatggagc
    22981 tgttcaagtc aacattatgg actatattta aaagaggaga tcgttatgtc gattaatgta
    23041 tttcaagcga ttttaattgg attatggaca gctttctgtt ttagtggaat gctgttagga
    23101 atttacacca atagatgtat tgttctgtca tttggtgtcg gaattattct aggtgatctg
    23161 cctactgctc ttgcaatggg agctattggt gaattggctt atatgggatt cggtgttggt
    23221 gctggaggta ctgttccacc aaacccaatc ggacctggta tctttggtac cttgatggct
    23281 atcactagtg ctggtaaagt cagtccagaa gcggctcttg ccctctctac tccgattgct
    23341 gtggcgattc aattcttaca aactttcgcc tacactgtac gtgctggtgc gcctgaaacg
    23401 gcgatgaagc acttgaaaaa ccataatttg aagaaattca agttcactct aaatgcaaca
    23461 atttggttgt ttgcctttat tggatttacc ttgggttgct tgggtgccct ttcaatggat
    23521 accttgttga aactcgtaga ctacattcca ccggtattac ttacaggttt gacagttgct
    23581 ggtaaaatgc tcccagctat cggttttgcg atgatcttgt cagtgatggc taagaaagag
    23641 ttgattccct ttgtcttgtt gggatatgtt tgtgcagctt atctaaacat cccaacaatt
    23701 ggtattgcaa ttgtaggtac tatctttgct ttgattgaat tttataacaa gccaaaaaca
    23761 gcggatcatg tggtagagga ggaagcacac gatgactgga tctaacaaat taacaaaacg
    23821 tgattatctt aaaacgtctt tgcgggcatt cttttgtcaa aatggattta actatagtaa
    23881 ctatcaaggg ttgggatatg ccaatgtaat gtatcctgct ttgaaaaaac actatggaga
    23941 ggatcaggaa ggtttctacc aagccttgga agaaaactgt gaattctata ataccaatcc
    24001 acacttcctg ccttttatta ccagcttgca ccttgtaatg ttggaaaatg gccgtccggc
    24061 aaaagaaaca cgtagcatca agatggcctt gatgggacca ttggcaggta ttggggattc
    24121 tctttctcaa ttctgtttag ctccattgtt ctcaaccatc gcagcttcgt ttgctcaaga
    24181 aggcttggtt gtcggtccaa tcttgttctt ccttgcgatg aatacgattt taacagcgat
    24241 taaattgtca actggtctgt atggatacaa actaggaaca actgtgattg ataaactaag
    24301 cgaacagatg gcaacgattt ctcgtattgc caatattatc ggtgtaaccg taattgctgg
    24361 tttggcagcg acatctgtta agattatggt gccgattacc tttgctgcag gggaagttaa
    24421 agcagacgct aaacaaagta tcgtaagtat tcagggaatg cttgataagg ttgctccagc
    24481 tcttctacca gccctattta cacttttagt ttactacttg atcaaagaaa agaaatggac
    24541 aacatataaa ctcgttattt taacagttat catcggaatt atcggaagct ggcttaagat
    24601 tatagcttaa tggatacaac attgttttat ggaatagtga ttgtcttggc agtgagtccc
    24661 cttttactgt caagctttca ttctattcgt cagcaaaagt tgcttcgcaa acagatggag
    24721 caacgacaag agtatttagc ttctttaaca tctggtgatg aagtgttgtt attgtctgga
    24781 attcatggaa aaatcatttc tatcaaagat gacttggtct ccttgcagat tgcaaaaggt
    24841 gtggtcatct atgtagaaaa ggaaagtgta atgggaaaga caaaagaact gctttttaag
    24901 tagttctttt tctggtaata gataatgaaa gaagaaagaa gacaattttt tgaaagagtc
    24961 gatggaaacc aatgtcgtga ttatatcttg tcccactgtt caaaagacta tgagaaagtc
    25021 aagagttccc ttgaacgctt gatggacaat cgttttatgt ttgatagtcc ttgggatatg
    25081 gagccttgtt caaaaatcca tcaaatccag ccgatggtat gggatcaagt atttgaagat
    25141 gatccagaat ggtcttatat gctcaatcga caagaatatc tcttgcagtt tatgataggg
    25201 tatctggtag aaggagataa ggactatatt caaaagtgca agttctttct atttgattgg
    25261 attgagcagg tgagagaatt ttctcctcaa tccttgatga ctagaacctt ggatacgggt
    25321 attcgttcct ttacttggtt gaaactactc ttgctcctct tgaaatttga cttgctagag
    25381 gagaaagaac tagagaaaat tttggtcagt ctagaaaagc agattgactt tatgaaaagc
    25441 tactatcgcg ccaagtacac ccttagtaac tgggggattt tacaaacaat tccgatgctt
    25501 gctatctatc atttcttttc agataagatg gacctagaag aagcttacca ttttgcttca
    25561 gaggagttga aacagcaaat tgagacacag attttaggag atggaagcca gtttgaacag
    25621 tcgattctct atcatgtaga ggtttataaa gccttgctgg atttgtgtct cttgcttcca
    25681 gacttgcaag atagttacca agagttgctg gaaaagatgg cgacctatat tcaaatgatg
    25741 acaggcttag atggacggac tttggctttt ggtgatagcg attctacaga aacgacagaa
    25801 atgttgagcc tgtctgctgt ggttttgaac aaggaagacc ttcttaacgg tctggatgtt
    25861 aaagtcgatt tgcttagcct cttgttcctg gggcgagaaa aggtcaagcg actgcaggaa
    25921 tttgaaagga gagcttggca gcctaagtcc atgatctttg aagactctgg acatgtctgc
    25981 attaaggatg aacatcgtta tctatttttc aaaaatggtc cgctaggaag tgcccatagc
    26041 catagtgacg agaatagttt ttgcttacag tatcaaggcc aacctatttt catagatgct
    26101 gggcgttatt cttatcggga gatatatgaa cgttatctct taaagagtgc ttggagtcat
    26161 tcgacctgca ttgtagatgg gaaagctccg gaaagaatca cgggatcctg ggaatatgaa
    26221 tactatcctc actccctgtt ttgtcaccat aaagaaaggg agggagtgca ttatattgag
    26281 ggggcttatt ggtcagcaga acctgatttg ccttatcttc acaagagaaa aatcctcatg
    26341 ttggtagagg atgtctggct cttggtagat gacatcaggt gtcaaggtca gcatgaggcg
    26401 ttgattcagt ttatccttga caaggatgtg acctatcaag atgggaaaat caatcagttg
    26461 agactatgga gtgaagttga ttttgatttg gaagatacca tcatttctcc taaatacaat
    26521 gagcttgaaa gaagtagcaa gctcaccaag cgccaattct ttgagaatca gatgctggat
    26581 tataccatca ttgcgcatga gagttttgaa atcatccgtc attctgtcta ccagacagat
    26641 gatcgtgaag tggaaaatgc tctggctttt gaagtgaaaa atgacgaaac agacaagctg
    26701 attctgttat taagcgagga tattggtgta ggtgaaaaat tgtgcctcgt tgacggaaca
    26761 aaaatgcgtg gaaaatgtct agtatatgat aaaataaatg agagaatgat tcgcttgcag
    26821 tgctagaaat aggcattttg aatagtgaat atgttataat aagtattagt aggaggtgtt
    26881 ttagattgga gaagaaactg accataaaag acattgcgga aatggctcag acctcgaaaa
    26941 caaccgtgtc attttaccta aacgggaaat atgaaaaaat gtcccaagag acacgtgaaa
    27001 agattgaaaa agttattcat gaaacaaatt acaaaccgag cattgttgcg cgtagcttaa
    27061 actccaaacg aacaaaatta atcggtgttt tgatcggtga tattaccaac agtttctcaa
    27121 accaaattgt taagggaatt gaggatatcg ccagccagaa tggctaccag gtaatgatag
    27181 gaaatagtaa ttacagccaa gagagtgagg accggtatat tgaaagcatg cttctcttgg
    27241 gagtagacgg ctttattatt cagccgacct ctaatttccg aaaatattct cgtatcatcg
    27301 atgagaaaaa gaagaaaatg gtcttttttg atagtcagct ctatgaacac cggactagct
    27361 gggttaaaac caataactat gatgccgttt atgacatgac ccagtcctgt atcgaaaaag
    27421 gttatgagca ttttctcttg attacagcgg atacgagtcg tttgagtact cggattgagc
    27481 gggcaagtgg ttttgtggat gctttaacag atgctaatat gcgtcacgcc agtctaacca
    27541 ttgaagataa gcatacgaat ttggaacaaa ttaaggaatt tttacaaaaa gaaatcgatc
    27601 ccgatgaaaa aactctggta tttatcccta actgttgggc cctacctcta gtctttaccg
    27661 ttatcaaaga gttgaattat aacttgccac aagttgggtt gattggtttt gacaatacgg
    27721 agtggacttg cttttcttct ccaagtgttt cgacgctggt tcagccctcc tttgaggaag
    27781 gacaacaggc tacaaagatt ttgattgacc agattgaagg ccgcaatcaa gaagaaaggc
    27841 aacaagtctt ggattgtagt gtgaattgga aagagtcgac tttctaaaat gaaggaaaat
    27901 gacttgcaat ctctgttaag aaataaaata atcccaccta gaacaagcta ggtgggatta
    27961 tttgcctatg aaatgagaaa ttatgggagc aagctcctaa atcaactgtt tttgatctac
    28021 ttctttaact acttgataaa agttatagaa gtaggccaaa cttgaaatga tggttacgac
    28081 taggaatatt gaaaatttcc attggacagg gttgcttaaa agttgtggaa aggatatgag
    28141 gagaaagaag agggctgcgt tgaggacagg tatccgtttt gattgtattt tctcaagtcc
    28201 tttattgagc gcaggaagaa agaggagtag gagtagtaaa actgtatgag aaacagctcc
    28261 tgaaataagg gcgaagaaaa ggaaaatact gataaaaaca tgaatgatca gtagtctagc
    28321 tagtgatttc ataaggcacc tcctaatcct ggtctttttt agctcttgca atacgaagtg
    28381 agtcgacaat atgtatcatc actccgaaaa agaaagctcc cagtatagtt ttaaaaatat
    28441 gttttgtatt tagaagagaa ctgataaaat ttggattttc acttgttagg gtatcaatga
    28501 gtggaattat aaaaaatatc actgttccat aaattgaacc tgctttcaga ccaggataac
    28561 gtaactgttt cttttctttt ttcatgagtt tcctcctaat cctcatcttg atttttctta
    28621 gtttttgcaa tgcgacggga gatgaggaac tgtatgctcg ctccgaagaa aatagaaccg
    28681 agaatgcttg atacaccatt tcttatagtg agaagagaat gaaaatagtc ctgaccttca
    28741 tctatgagta tactgagaag aggagttata aaaaacatcc atagaccaaa gaacaaacct
    28801 gctttaagac ctaggtagtg tagttgcttg ctttctttct cattcagcat atctggttca
    28861 atgactgtga tgcctgtttt tttcatttgg taggtgacat agccagcagc gatgagggca
    28921 atcactaaaa tcagaggagg atagattaga gccacttttt gagggtattt ataggccaga
    28981 aggagtggaa taagatttcc gaaaatcatc agataaaaga ggatgataaa gacttggttc
    29041 ccaatactat cggcctcacg ccgtttgtat tcgtcaaggg gaccagaaat accgtatgtg
    29101 cgtttgatca gtttttcagt gaaggtttct tttttcatga gtttgctcct tttttaaaaa
    29161 tcttcctccc aaaagagact gttgaggtca gtttggaggc tgcgggcgag attgagacag
    29221 agttccaagg ttggattgta cttgtcgttt tcaatcatat tgatagtctg tctcgagaca
    29281 ccgatatcct tggcgagttc gagctgggaa atacccaatt ccttgcgaaa ttctttcaca
    29341 cgattcatct gatctccttt ttgatttatg tcgtatatat ttgactttat tatagtcttt
    29401 taaacataaa gtgtcaagta tttttgacat attttttgaa gaaatagtag tctccttgtc
    29461 ctatttgtct gacaagtgca agctggtcgg atttgtggta aaatagataa gatatgacaa
    29521 aagaatttca tcatgtaacg gtcttactcc acgaaacgat tgatatgctt gacgtaaaac
    29581 ctgacggtat ctacgttgat gcgactttgg gcggagcagg acatagcgag tatttattaa
    29641 gtaaattaag tgaaaaaggc catctctatg cctttgacca ggatcagaat gccattgaca
    29701 atgcgcaaaa acgcttggca ccttacattg agaagggaat ggtgaccttt atcaaggata
    29761 acttccgtca tttacaggca cgtttgcgcg aagctggtgt tcaggaaatt gatggaattt
    29821 gttatgactt gggagtgtct agtcctcaat tggaccagcg tgagcgtggt ttttcttata
    29881 aaaaggatgc gccactggac atgcggatga atcaggatgc tagtctgaca gcctatgaag
    29941 tggttaatca ctatgactat catgatttgg ttcgtatttt cttcaaatac ggtgaggata
    30001 aattctctaa acagattgcg cgtaagattg agcaagcgcg tgaagtgaag ccgattgaga
    30061 caacgactga gttagcagag attatcaagt tggtcaaacc tgccaaggaa ctcaagaaga
    30121 agggtcatcc tgctaagcag attttccagg ctattcgaat tgaagtcaat gatgaactgg
    30181 gggcggcaga tgagtccatc cagcaggcta tggatatgtt ggctctggat ggtagaattt
    30241 cagtgattac ctttcattcc ttagaagacc gcttgaccaa gcaattgttc aaggaagctt
    30301 caacagttga agttccaaaa ggcttgcctt tcatcccaga tgatctcaag cccaagatgg
    30361 aattggtgtc ccgtaagcca atcttgccaa gtgcggaaga gttagaagcc aataaccgct
    30421 cgcactcagc caagttgcgc gtggccagaa aaattcacaa gtaagaggga aaaagatggc
    30481 agaaaaaatg gaaaaaacag gtcaaatact acagatgcaa cttaaacggt tttcgcgtgt
    30541 ggaaaaagct ttttactttt ccattgctgt aaccactctt attgtagcca ttagtattat
    30601 ttttatgcag accaagctct tgcaagtgca gaatgatttg acaaaaatca atgcgcagat
    30661 agaggaaaag aagaccgaat tggacgatgc caagcaagag gtcaatgaac tattacgtgc
    30721 agaacgtttg aaagaaattg ccaattcaca cgatttgcaa ttaaacaatg aaaatattag
    30781 aatagcggag taagatatga agtggacaaa aagagtaatc cgttatgcga ccaaaaatcg
    30841 gaaatcgccg gctgaaaaca gacgcagagt tggaaaaagt ctgagtttat tatctgtctt
    30901 tgtttttgcc atttttttag tcaattttgc ggtcattatt gggacaggca ctcgctttgg
    30961 aacagattta gcgaaggaag ctaagaaggt tcatcaaacc acccgtacag ttcctgccaa
    31021 acgtgggact atttatgacc gaaatggagt cccgattgct gaggatgcaa cctcctataa
    31081 tgtctatgcg gtcattgatg agaactataa gtcagcaacg ggtaagattc tttacgtaga
    31141 aaaaacacaa tttaacaagg ttgcagaggt ctttcataag tatctggaca tggaagaatc
    31201 ctatgtaaga gagcaactct cgcaacctaa tctcaagcaa gtttcctttg gagcaaaggg
    31261 aaatgggatt acctatgcca atatgatgtc tatcaaaaaa gaattggaag ctgcagaggt
    31321 caaggggatt gattttacaa ccagtcccaa tcgtagttac ccaaacggac aatttgcttc
    31381 tagttttatc ggtctagctc agctccatga aaatgaagat ggaagcaaga gcttgctggg
    31441 aacctctgga atggagagtt ccttgaacag tattcttgca gggacagacg gcattattac
    31501 ctatgaaaag gatcgtctgg gtaatattgt acccggaaca gaacaagttt cccaacgaac
    31561 gatggacggt aaggatgttt atacaaccat ttccagcccc ctccagtcct ttatggaaac
    31621 ccagatggat gcttttcaag agaaggtaaa aggaaagtac atgacagcga ctttggtcag
    31681 tgctaaaaca ggggaaattc tggcaacaac gcaacgaccg acctttgatg cagatacaaa
    31741 agaaggcatt acagaggact ttgtttggcg tgatatcctt taccaaagta actatgagcc
    31801 aggttccact atgaaagtga tgatgttggc tgctgctatt gataataata cctttccagg
    31861 aggagaagtc tttaatagta gtgagttaaa aattgcagat gccacgattc gagattggga
    31921 cgttaatgaa ggattgactg gtggcagaat gatgactttt tctcaaggtt ttgcacactc
    31981 aagtaacgtt gggatgactc tccttgagca aaagatggga gatgctacct ggcttgatta
    32041 tcttaatcgt tttaaatttg gagttccgac ccgtttcggt ttgacggatg agtatgctgg
    32101 tcagcttcct gcggataata ttgtcaacat tgcgcaaagc tcatttggac aagggatttc
    32161 agtgacccag acacaaatga ttcgtgcctt tacagctatt gctaatgacg gtgtcatgct
    32221 ggagcctaaa tttattagtg ccatttatga tccaaatgat caaactgctc ggaaatctca
    32281 aaaagaaatt gtgggaaatc ctgtttctaa agatgcagct agtctaactc ggactaacat
    32341 ggttttggta gggacggatc cggtttatgg aaccatgtat aaccacagca caggcaagcc
    32401 aactgtaact gttcctgggc aaaatgtagc cctcaagtct ggtacggctc agattgctga
    32461 cgagaaaaat ggtggttatc tagtcggggt aaccgactat attttctcgg ctgtatcgat
    32521 gagtccggct gaaaatcctg attttatctt gtatgtgacg gtccaacaac ctgaacatta
    32581 ttcaggtatt cagttgggag aatttgccaa tcctatcttg gagcgggctt cagctatgaa
    32641 agactctctc aatcttcaaa caacagctaa agctttggag caagtaagtc aacaaagtcc
    32701 ttatcctatg cctagtgtca aggatatttc acctggtgat ttagcagaag aattgcgtcg
    32761 caatcttgta caacccatcg ttgtgggaac aggaacgaag attaaaaaca gttctgctga
    32821 agaagggaag aatcttgccc cgaaccagca agtccttatc ttatctgata aagcagagga
    32881 agttccagat atgtatggtt ggacaaagga gactgctgag acctttgcta agtggctcaa
    32941 tatagaactt gaatttcaag gttcgggctc tactgtgcag aagcaagatg ttcgtgctaa
    33001 cacagctatc aaggacatta aaaaaattac attaacttta ggagactaat atgtttattt
    33061 ccatcagtgc tggaattgtg acatttttac taactttagt aggaattccg gcctttatcc
    33121 aattttatag aaaggcgcaa attacaggcc agcagatgca tgaagatgtc aaacagcatc
    33181 aggcaaaagc tgggactcct acaatgggag gtttggtttt cttgattact tctgttttgg
    33241 ttgctttctt tttcgcccta tttagtagcc aattcagcaa taatgtggga atgattttgt
    33301 tcatattagt cttgtatggc ttggtcggat ttttagatga ctttctcaag gtctttcgta
    33361 aaatcaatga ggggcttaat cctaagcaaa aattagctct tcagcttcta ggtggaatta
    33421 tcttctatct tttctatgag cgtgggggcg atatcctgtc tgtctttggt tatccagttc
    33481 atttgggatt tttctatatt ttcttcgctc ttttctggct agtcggtttt tcaaacgcag
    33541 taaacttgac agacggtgtt gacggtttag ctagtatttc cgttgtgatt agtttgtctg
    33601 cctatggagt tattgcctat gtgcaaggtc agatggatat tcttctagtg attcttgcca
    33661 tgattggtgg tttgctcggt ttcttcatct ttaaccataa gcctgccaag gtctttatgg
    33721 gtgatgtggg aagtttggcc ctaggtggga tgctggcagc tatctctatg gctctccacc
    33781 aagaatggac tctcttgatt atcggaattg tatatgtttt tgaaacaact tctgttatga
    33841 tgcaagtcag ttatttcaaa ctgacaggtg gtaaacgtat tttccgtatg acgcctgtac
    33901 atcaccattt tgagcttggg ggattgtctg gtaaaggaaa tccttggagc gagtggaagg
    33961 ttgacttctt cttttgggga gtgggacttc tagcaagtct cctgacccta gcaattttgt
    34021 atttaatgta agaatggcat cctgatgttt cagggtgttt ttgtatttaa atacacaatg
    34081 aaaatcaaag aacaaactag aaagctaact ttaggctgct caaa
//
LOCUS       DAVBOG010000021        34102 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.021, whole genome shotgun sequence.
ACCESSION   DAVBOG010000021 DAVBOG010000000
VERSION     DAVBOG010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 34102)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34102)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34102
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.021"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            85..366
                     /locus_tag="VQ865_001059"
     CDS             85..366
                     /locus_tag="VQ865_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000380698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HET3135406.1"
                     /translation="MDTPDENGYVADDYRITYLEAHIKAMRDAIYQDGIDLLGYTTWS
                     CIDPVSAGTGEMNKRYGFIYVDRDNVGNGTLKRSKKKSFYWYMSFIAMV"
     gene            498..1442
                     /gene="manA"
                     /locus_tag="VQ865_001060"
     CDS             498..1442
                     /gene="manA"
                     /locus_tag="VQ865_001060"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HET3135407.1"
                     /translation="MSEPLFLQSVMQEKIWGGTKLRDEFGYDIPSEKVGEYWAISAHL
                     NGVSKVANGRYEGTDLATLYAEHRELFGNRPEPVFPLLTKILDANDWLSVQVHPDDAY
                     GLEHEGELGKTECWYIIAADEGSEIIYGHNAKSKEELRQQIEDKNWDALLTKVPVKAG
                     DFFYVPSGTMHAIGAGILILETQQSSDTTYRVYDFDRKDDKGNLRELHLEKSIDVLNI
                     GEPANSRPVTIKADDLRSTLLVSNDFFAVYKWEITGKVNFEKTADYSLLSVLAGQGQL
                     TVDGKNYPIQKGRHFILPSDVEAWTLEGQDLELIVSHP"
     gene            complement(1433..2937)
                     /locus_tag="VQ865_001061"
                     /pseudo
     CDS             complement(1433..2937)
                     /locus_tag="VQ865_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844893.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-dependent transporter"
     gene            3042..3782
                     /locus_tag="VQ865_001062"
     CDS             3042..3782
                     /locus_tag="VQ865_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000274781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3135408.1"
                     /translation="MYHIKEAAQLSGVSVKTLHHYDKIGLLVPLKSENGYRTYSQEDL
                     ERLQVILYYKYLGFSLEKIAELLKEERTDLLPHLTRQLDYLTRERQHLDTLISTLQKT
                     IQEQKGERKMTIEEKFTGFSYQDNQKYHQEAVEKYGQEVMGQALERQKGHEDEATAAF
                     NQVFQTLAQNLQVGLPATATENQEQAAKLLQAIRTYGFDCSIEVFGHIGKGYVYNPEF
                     KENIDKFGSETAQYTSDAIAAYVQTNAE"
     gene            complement(3811..4266)
                     /locus_tag="VQ865_001063"
     CDS             complement(3811..4266)
                     /locus_tag="VQ865_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001081770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3135409.1"
                     /translation="MNRREAVEFVNMCMIKNGDKVLVQDRVSPDWSGITFPGGHVERG
                     ESFVDAVIREVKEETGLIISKPQLCGIKNWYDDKDYRYVVLFYKTEHFTGELQSSDEG
                     KVWWEDFENLSHLKLATDDMSDMLRVFLEEDLSEFFYYKNGDDWLYDLK"
     gene            complement(4286..5461)
                     /locus_tag="VQ865_001064"
     CDS             complement(4286..5461)
                     /locus_tag="VQ865_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HET3135410.1"
                     /translation="MKHFDTIVIGGGPAGMMATISSSFYGQKTLLIEKNRKLGKKLAG
                     TGGGRCNVTNNGSLDNLLAGIPGNGRFLYSVFSQFDNHDIINFFTENGVKLKVEDHGR
                     VFPASDKSRTIIEALEKKITELGGQVATQIEIVSVKKVDNQFVLKSADQTFTCEKLIV
                     TTGGKSYPSTGSTGFGHEIARHFKHTITDLEAAESPLLTDFPHKALQGISLDEVTLSY
                     GKHVITHDLLFTHFGLSGPAALRMSSFVKGGEVLSLDVLPQLSEKDLVTFLEENREKS
                     LKNALKTLLPERLAEFFVQGYPEKVKQLTEKEREQLVQSIKELKIPVTGKMSLAKSFV
                     TKGGVSLKEINPKTLESKLVPGLHFAGEVMDINAHTGGFNITSALCTGWVAGSLHYD"
     gene            complement(5520..6365)
                     /locus_tag="VQ865_001065"
     CDS             complement(5520..6365)
                     /locus_tag="VQ865_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3135411.1"
                     /translation="MTWKIIADSGCDYRQLPTPAINTTFVSVPLTIQVADQVFVDDAS
                     LDIDQMMETMYATAEASKSACPSPDDYLRAFEGAKNIFLVTITGTLSGSHNSAQLAKN
                     IYLEDHPDTKIHVIDSLSAGGEVDLLVEKLNDLIDQGLSFEEVVEAITAYQEKTKLLF
                     VLAKVDNLVKNGRLSKLIGTVVGLLNIRMVGKASETGTLELLQKARGSKKSVQAAYDE
                     LVKAGYAGGRIVMAQRNNEKCCQQLSERIRETFPQADIKILPTSGLCSFYAEEGGLLM
                     GYEID"
     gene            6490..7047
                     /locus_tag="VQ865_001066"
     CDS             6490..7047
                     /locus_tag="VQ865_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3135412.1"
                     /translation="MSERRISEKSLENLRKSNQESNLLTREAIETALLQLLEKKELTK
                     ISISELVKRAGVSRAAFYRNYDSKEEILESVFKRTVHNIMEQLHHYDLKTDLYLVWVH
                     LFREARKEARVIQLALDYHLEKIFVQAMQEFLEKYHGKSKGVSSYLHSFWSSAIVSVL
                     LKWIKDGMKVPAEKIADLGLPFFKK"
     gene            7066..7533
                     /locus_tag="VQ865_001067"
     CDS             7066..7533
                     /locus_tag="VQ865_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000138511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine/deoxycytidylate deaminase family
                     protein"
                     /protein_id="HET3135413.1"
                     /translation="MTEKRLAWDEYFAAQALLIANRSTCKRAKVGAILVKDNKVISTG
                     YNGSVSGTEHCIDHECLVIEGHCVRTLHAEVNAILQGAERGVPKGFTAYVTHFPCLNC
                     TKQLLQVGCKRVVYINQYRMDDYAQYLYQEKGTELTHLPLETVQTALKEADLM"
     gene            7622..8251
                     /gene="upp"
                     /locus_tag="VQ865_001068"
     CDS             7622..8251
                     /gene="upp"
                     /locus_tag="VQ865_001068"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HET3135414.1"
                     /translation="MGKIEVINHPLIQHKLSILRRIDTSTKAFRELVDEIAMLMGYEV
                     LRDLPLEDVEIETPITKTVQKQLAGKKLAIVPILRAGIGMVDGLLSLVPAAKVGHIGM
                     YRDEETLQPVEYLVKLPEDIDQRQIFVVDPMLATGGSAILAVDSLKKRGASNIKFVCL
                     VSAPEGVKALQEAHPDVEIFTAALDERLNEHGYIVPGLGDAGDRLFGTK"
     gene            8425..9015
                     /gene="clpP"
                     /locus_tag="VQ865_001069"
     CDS             8425..9015
                     /gene="clpP"
                     /locus_tag="VQ865_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease proteolytic subunit
                     ClpP"
                     /protein_id="HET3135415.1"
                     /translation="MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIA
                     QLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMNFIKADVQTIVMGMAASMGTVIA
                     SSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
                     SMEKVHADAERDNWMSAHETLEYGFIDEIMANNSLN"
     gene            9094..9342
                     /locus_tag="VQ865_001070"
     CDS             9094..9342
                     /locus_tag="VQ865_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HET3135416.1"
                     /translation="MFEKVNRSGLIIYLYYNRDAKKLQDYGDITYHSKKHRYLQLYVP
                     TQEVEQLVGRLSKEKFIKKVRVCHIQELETPFVGNLYR"
     gene            9443..10603
                     /locus_tag="VQ865_001071"
     CDS             9443..10603
                     /locus_tag="VQ865_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3135417.1"
                     /translation="MKKKFALSFVALASVALLAACGEVKSGAVNTAGNSVEEKTIKIG
                     FNFEESGSLAAYGTAEQKGAQLAVDEINAAGGIDGKQIEVVDKDNKSETAEAASVTTN
                     LVTQSKVSAVVGPATSGATAAAVANATKAGVPLISPSATQDGLTKGQDYLFIGTFQDS
                     FQGKIISNYVSEKLNAKKVVLYTDNASDYAKGIAKSFRESYKGEIVADETFVAGDTDF
                     QAALTKMKGKDFDAIVVPGYYNEAGKIVNQARGMGIDKPIVGGDGFNGEEFVQQATAE
                     KASNIYFISGFSTTVEVSAKAKAFLDAYRAKYNEEPSTFAALAYDSVHLVANAAKGAK
                     NSGEIKDNLAKTKDFEGVTGQTSFDADHNTVKTAYMMTMNNGKVEVAEVVKP"
     gene            10871..11740
                     /locus_tag="VQ865_001072"
     CDS             10871..11740
                     /locus_tag="VQ865_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3135418.1"
                     /translation="MLQQLVNGLILGSVYALLALGYTMVYGIIKLINFAHGDIYMMGA
                     FIGYFLINSFQMNFFVALIVAMLATAILGVVIEFLAYRPLRHSTRIAVLITAIGVSFL
                     LEYGMVYLVGANTRAFPQAIQTVRYDLGPISLTNVQLMILGISLILMILLQVIVQKTK
                     MGKAMRAVSVDSDAAQLMGINVNRTISFTFALGSALAGAAGVLIALYYNSLEPLMGVT
                     PGLKSFVAAVLGGIGIIPGAALGGFVIGLLETFATAFGMSDFRDAIVYGILLLILIVR
                     PAGILGKNVKEKV"
     gene            11744..12700
                     /locus_tag="VQ865_001073"
     CDS             11744..12700
                     /locus_tag="VQ865_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="HET3135419.1"
                     /translation="MKENLKVNILWLLLLLAGYSLISVLVSVGVLNLFYVQILQQIGI
                     NIILAVGLNLIVGFSGQFSLGHAGFMAIGAYAAAIIGSKSPTYGAFFGAMLVGALLSG
                     AVALLVGIPTLRLKGDYLAVATLGVSEIIRIFIINGGSLTNGAAGILGIPNFTTWQMV
                     YFFVVITTIATLNFLRSPIGRSTLSVREDEIAAESVGVNTTKIKIIAFVFGAITASIA
                     GSLQAGFIGSVVPKDYTFINSINVLIIVVFGGLGSITGAIVSAIVLGILNMLLQDVAS
                     VRMIIYALALVLVMIFRPGGLLGTWELSLSRFFKKSKKEEQN"
     gene            12700..13464
                     /locus_tag="VQ865_001074"
     CDS             12700..13464
                     /locus_tag="VQ865_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135420.1"
                     /translation="MALLEVKQLTKHFGGLTAVGDVTLELNEGELVGLIGPNGAGKTT
                     LFNLLTGVYEPSEGTVTLDGHLLNGKSPYKIASLGLGRTFQNIRLFKDLTVLDNVLIA
                     FGNHHKQHVFTSFLRLPAFYKSEKELKAKALELLKIFDLDGDAETLAKNLSYGQQRRL
                     EIVRALATEPKILFLDEPAAGMNPQETAELTELIRRIKDEFKITIMLIEHDMNLVMEV
                     TERIYVLEYGRLIAQGTPDEIKTNKRVIEAYLGGEA"
     gene            13464..14174
                     /locus_tag="VQ865_001075"
     CDS             13464..14174
                     /locus_tag="VQ865_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000062217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135421.1"
                     /translation="MSMLKVENLSVHYGMIQAVRDVSFEVNEGEVVSLIGANGAGKTT
                     ILRTLSGLVRPSSGKIEFLGQEIQKMPAQKIVAGGLSQVPEGRHVFPGLTVMENLEMG
                     AFLKKNREENQANLKKVFSRFPRLEERKNQDAATLSGGEQQMLAMGRALMSTPKLLLL
                     DEPSMGLAPIFIQEIFDIIQDIQKQETTVLLIEQNANKALAISDRGYVLETGKIVLSG
                     TGKELASSEEVRKAYLGG"
     gene            14482..15138
                     /locus_tag="VQ865_001076"
     CDS             14482..15138
                     /locus_tag="VQ865_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3135422.1"
                     /translation="MAVKDFMTRKVVYISPDTTVSHAADLMREQGLHRLPVIENDQLV
                     GLVTEGTIAQASPSKATSLSIYEMNYLLNKTKVKDVMIRDVVTVSGYASLEDATYLML
                     KNKISILPVVDNHQVYGVITDRDVFQAFLEIAGYGEEGIRVRFVTEDEVGVLGKIVSL
                     IVEENLNISHTVNIPRKDGKVIIEVQIDGSIDLPALKEKFEANGIQVEEIARTSAKVL
                     "
     gene            15246..16341
                     /gene="prfB"
                     /locus_tag="VQ865_001077"
     CDS             join(15246..15317,15319..16341)
                     /gene="prfB"
                     /locus_tag="VQ865_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511312.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HET3135423.1"
                     /translation="MDISVIRQKIDANREKLASFRGSLDLEGLEEEIAILENKMTEPD
                     FWNDNIAAQKTSQELNELKNTYNTFHKMEELQDEVEILLDFLAEDESVHDELVAQLAE
                     LDKIMTSYEMTLLLSEPYDHNNAILEIHPGSGGTEAQDWGDMLLRMYTRYGNAKGFKV
                     EVLDYQAGDEAGIKSVTLSFEGPNAYGLLKSEMGVHRLVRISPFDSAKRRHTSFTSVE
                     VMPELDDTIEVEIREDDIKMDTFRSGGAGGQNVNKVSTGVRLTHIPTGIVVQSTVDRT
                     QYGNRDRAMKMLQAKLYQMEQDKKAAEVDSLKGEKKEITWGSQIRSYVFTPYTMVKDH
                     RTSFEVAQVDKVMDGDLDGFIDAYLKWRIS"
     gene            16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ865_001078"
     CDS             16359..17051
                     /gene="ftsE"
                     /locus_tag="VQ865_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012130521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HET3135424.1"
                     /translation="MSIIEMRDVVKKYDNGTTALRGVSVSVQPGEFAYIVGPSGAGKS
                     TFIRSLYREVKIDKGSLSVAGFNLVKIKKKDVPLLRRSVGVVFQDYKLLPKKTVYENI
                     AYAMEVIGENRRNIKRRVMEVLDLVGLKHKVRSFPNELSGGEQQRIAIARAIVNNPKV
                     LIADEPTGNLDPDNSWEIMNLLERINLQGTTILMATHNSQIVNTLRHRVIAIENGRVV
                     RDESKGEYGYDD"
     gene            17044..17970
                     /locus_tag="VQ865_001079"
     CDS             17044..17970
                     /locus_tag="VQ865_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135425.1"
                     /translation="MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVI
                     FNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKS
                     VTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGV
                     SEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMR
                     LVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPD
                     LFSPLMIALLFVIGVFIGSLGSGISMRRFLKI"
     gene            18256..20436
                     /locus_tag="VQ865_001080"
     CDS             18256..20436
                     /locus_tag="VQ865_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000974069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3135426.1"
                     /translation="MMKDTFKNVLSFEFWQKFGKALMVVIAVMPAAGLMISIGKSIVM
                     INPTFTPLVITGGILEQIGWGVIGNLHILFALAIGGSWAKERAGGAFAAGLAFILINR
                     ITGTIFGVSGDMLKNPDAMVTTFFGGSIKVADYFISVLEAPALNMGVFVGIISGFVGA
                     TAYNKYYNFRKLPDALSFFNGKRFVPFVVILRSAIAAILLAAFWPVVQTGINNFGIWI
                     ANSQETAPILAPFLYGTLERLLLPFGLHHMLTIPMNYTALGGTYDILTGAAKGTQVFG
                     QDPLWLAWVTDLVNLKGTDTSQYQHLLDTVHPARFKVGQMIGSFGILMGVIVAIYRNV
                     DADKKHKYKGMMIATALATFLTGVTEPIEYMFMFIATPMYLVYSLVQGAAFAMADVVN
                     LRMHSFGSIEFLTRTPIAISAGIGMDIVNFVWVTVLFAVIMYFIANFMIQKFNYATPG
                     RNGNYETAEGSEETSSEVKVAAGSQAVNIINLLGGRVNIVDVDACMTRLRVTVKDADK
                     VGNAEQWKAEGAMGLVMKGQGVQAIYGPKADILKSDIQDILDSGEIIPETLPSQMTEA
                     QQNTVHFKNLTEEVYSVADGQVVGLEQVKDPVFAQKMMGDGFAVEPANGNIVSPVSGT
                     VSSIFPTKHAFGIVTEAGLEVLVHIGLDTVSLEGKPFTVHVAEGQKVAAGDLLVTADL
                     DAIRAAGRETSTVVVFTNGDAIKSVKLEKTGSLAAKTAVAKVEL"
     gene            20488..21303
                     /locus_tag="VQ865_001081"
     CDS             20488..21303
                     /locus_tag="VQ865_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HET3135427.1"
                     /translation="MKFLTLNTHSWMEKEAEEKFQILLEDILEKDYDLICFQEINQEM
                     TSSEVEVNDLYQALPAAEPIHQDHYVRLLVEKLLEQGKNYYWTWAYNHIGYDRYHEGV
                     AILSKTPIEAREILVSDVDDPTDYHTRRVALAETVVDGKELAVASVHLSWWDKGFQEE
                     WARFEAVLKKLNKPLLLAGDFNNPAGQEGYQAILASPLGLQDAFEVAQEKSGSYTVPP
                     EIDGWKGNTEPLRIDYVFTTKELAVENLHVVFDGNKSPQVSDHYGLNAILNWK"
     gene            21443..22786
                     /locus_tag="VQ865_001082"
     CDS             21443..22786
                     /locus_tag="VQ865_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3135428.1"
                     /translation="MSFTKFQFKNYIREALKELKFTTPTEVQDKLIPIVLAGRDLVGE
                     SKTGSGKTHTFLLPIFQQLDEASDSVQAVITAPSRELATQIYQVARQISAHSDVEVRV
                     VNYVGGTDKARQIEKLASNQPHIVIGTPGRIYDLVKSGDLAIHKAKTFVVDEADMTLD
                     MGFLETVDKIADSLPKDLQFMVFSATIPQKLQPFLKKYLSNPVMEKIKTKTVISDTID
                     NWLISTKGHDKNAQIYQLTQSMQPYLAMIFVNTKTRADELHSYLTAQGLKVAKIHGDI
                     APRERKRIMNQVQNLDFEYIVATDLAARGIDIEGVSHVINDAIPQDLSFFVHRVGRTG
                     RNGLPGTAITLYQPSDDSDIRELEKLGIKFSPKMVKDGEFQDTYDRDRRANREKKQDK
                     LDIEMIGLVKKKKKKVKPGYKKKIQWAVDEKRRKTKRAENRARGRAERKAKRQTF"
     gene            23163..24353
                     /locus_tag="VQ865_001083"
     CDS             23163..24353
                     /locus_tag="VQ865_001083"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HET3135429.1"
                     /translation="MSERKLFTSESVSEGHPDKIADQISDAILDAILAKDPEAHVAAE
                     TAVYTGSVHVFGEISTNAYVDINRVVRDTIAEIGYTNTEYGFSAETVGVHPSLVEQSP
                     DIAQGVNEALEVRGNADQDPLDLIGAGDQGLMFGFAVDETEELMPLPIALSHKLVRRL
                     AELRKSGEISYLRPDAKSQVTVEYDENDRPVRVDTVVISTQHDPEATNEQIHQDVIDK
                     VIKEVIPSSYLDDKAKFFINPTGRFVIGGPQGDSGLTGRKIIVDTYGGYSRHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLAKKAEVQLAYAIGVAQPVSVRIDTFGTGTVA
                     ESQLEKAARQIFDLRPAGIIQMLDLKRPIYRQTSAYGHMGRTDIDLPWERLDKVDALK
                     EAVK"
     gene            24906..25841
                     /locus_tag="VQ865_001084"
     CDS             24906..25841
                     /locus_tag="VQ865_001084"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HET3135430.1"
                     /translation="MVSTKTQIAGFEFDNCLMNAAGVACMTIEELEEVKNSAAGTFVT
                     KTATLDFRQGNPEPRYQDVPLGSINSMGLPNNGLDYYLDYLLDLQEKESNRTFFLSLV
                     GMSPEETHTILKKVQESDFRGLTELNLSCPNVPGKPQIAYDFETTDRILAEVFAYFTK
                     PLGIKLPPYFDIVHFDQAAAIFNKYPLKFVNCVNSIGNGLYIEDESVVIRPKNGFGGI
                     GGEYIKPTALANVHAFYQRLNPQIQIIGTGGVLTGRDAFEHILCGASMVQVGTTLHKE
                     GVSAFDRITNELKAIMVEKGYESLEDFRGKLRYID"
     gene            25875..26912
                     /locus_tag="VQ865_001085"
     CDS             25875..26912
                     /locus_tag="VQ865_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3135431.1"
                     /translation="MLAIEESQKLTLSNLPSLSLFTGTDQGQFEVMKSQMLKQIGYDS
                     ADLNFAYFDMKEVVYKDVELELVSLPFFADEKIVILDYFMDITTAKKRFLTDDELKSF
                     EEYLDNPSPTTKLIIFAEGKLDSKRRLVKLLKRDAKVFDAVEVKEQELRQYFQKWSQK
                     QGLQFTNHSFENLLIKSGFQFSEIQKNLLFLQSYKANSVIEEEDIVNAIPKTLQDNIF
                     DLTQFILTKKMDQARDLVRDLTLQGEDEIKLIAVMLGQFRTFTQVKILAESGQTESQI
                     ASSLGSYLGRNPNPYQIKFALRDSRGLSLSFLKQAISYLIETDYQIKTGLYEKGFLFE
                     KALLQIASQVN"
     gene            27085..27690
                     /locus_tag="VQ865_001086"
     CDS             27085..27690
                     /locus_tag="VQ865_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HET3135432.1"
                     /translation="MAIILPELPYAYDALEPYIDAETMHLHHDKHHQTYVNNANAALE
                     KHPEIGEDLEALLADVESIPADIRQALINNGGGHLNHALFWELMTPEKTAPSAELAAA
                     IDATFGSFEEFQAAFTAAATTRFGSGWAWLVVNKEGKLEVTSTANQDTPISEGKKPIL
                     GLDVWEHAYYVKYRNVRPDYIKAFFSVINWNKVDELYAAAK"
     gene            27846..28376
                     /locus_tag="VQ865_001087"
     CDS             27846..28376
                     /locus_tag="VQ865_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HET3135433.1"
                     /translation="MRKEIAPELYNYNKFPGPEFHLHGDKVETEGIAFSLVENIKDAF
                     DVTTFNQRFSEVLTKFDYIVGDWSNEQLRLRGFYKDDRTEEKLEKISRLQDYLLEYCS
                     YGCAYFVLENEAPKRASFDKKMRKTEEETPSRKGKKPTQTKRKSNADKKNRRRQKDQH
                     SQKEDKEQRHFVIRQK"
     gene            28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ865_001088"
     CDS             28397..29482
                     /gene="rlmN"
                     /locus_tag="VQ865_001088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000804770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HET3135434.1"
                     /translation="MKPSIHSLTHQTMQEWVLEQGEKKFRADQIWEWLYRKRVQSFEE
                     MTNLSKDLIAKLNDQFVVNPLKQGIVQESADGTVKYLFELPDGMLIETVLMCQHYGLS
                     VCVTTQVGCNIGCTFCASGLIKKQRDLNNGEIVAQIMLVQKYFDERGQDERISHIVVM
                     GIGEPFDNYNNVLNFFRTINDDKGMAIGARHITVSISGLAHKIRDFADEGVQVNLAVS
                     LHAPNNELRSSIMKINRAFPIEKLFAAIEYYIETTNRRVTFEYIMLNEVNDGVEQALE
                     LAELLKNIKKSSYVNLIPYNPVSEHDQYSRSPKERVLAFYDTLKKKGGNCVVRQEHGT
                     DIDAACGQLLFNTMKRDRQKAVAAVNP"
     gene            29482..29964
                     /locus_tag="VQ865_001089"
     CDS             29482..29964
                     /locus_tag="VQ865_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HET3135435.1"
                     /translation="MMKKTYNHILVWGVIFYSICIVYFCFTPQEQSTVGVGTPDIQHL
                     GRLVFLLTPFNSLWKLGEVSDIGQLCWIFLQNILNVFLFFPLIFQLLYLFPNLRKTKK
                     VLLFSFLVSLGIECTQLILDFFFDFNRVFEIDDLWTNTLGGYLAWLLYKRLHKNKIRN
                     "
     gene            29966..31507
                     /locus_tag="VQ865_001090"
     CDS             29966..31507
                     /locus_tag="VQ865_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002918612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3135436.1"
                     /translation="MSILEVKNLSHGFGDRAIFEDVSFRLLKGEHIGLVGANGEGKST
                     FMSIVTGKMLPDEGKVEWSKYVTAGYLDQHSVLAERQSVRDVLRTAFDELFKAEARIN
                     DLYMEMAEDGADVDALMEEVGELQDRLESRDFYTLDAKIDEVARALGVMDFGMDTDVT
                     SLSGGQRTKVLLAKLLLEKPDILLLDEPTNYLDAEHIDWLKRYLQNYENAFVLISHDI
                     PFLNDVINIVYHVENQQLTRYSGDYYQFQEVYAMKKSQLEAAYERQQKEIADLKDFVA
                     RNKARVATRNMAMSRQKKLDKMDIIELQSEKPKPSFDFKPARTPGRFIFQTKNLQIGY
                     DLPLTKPLNLTFERNQKVAIIGANGIGKTTLLKSLLGIISPIAGEVERGDYLELGYFE
                     QEVEGGNRQTPLEAVWNAFPALNQAEVRAALARCGLTTKHIESQIQVLSGGEQAKVRF
                     CLLMNRENNVLVLDEPTNHLDVDAKDELKRALKEYRGSILMVCHEPDFYEGWIDQIWD
                     FNNLT"
     gene            complement(31563..32366)
                     /locus_tag="VQ865_001091"
     CDS             complement(31563..32366)
                     /locus_tag="VQ865_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3135437.1"
                     /translation="MKKLATLLLLSTVALAGCSSVQRSLRGDDYVDSSLAAEESSKVA
                     AQSAKELNDALTNENANFPQLSKEVAEDEAEVILHTSQGDIRIKLFPKLAPLAVENFL
                     THAKEGYYNGITFHRVIDGFMVQTGDPKGDGTGGQSIWHDKDKTKDKGTGFKNEITPY
                     LYNIRGALAMANTGQPNTNGSQFFINQSSTDTSSKLPTSKYPQKIIEAYKEGGNPSLD
                     GKHPVFGQVIDGMDVVDKIAKAEKDEKDKPTTAITIDSIEVVKDYDFKS"
     gene            complement(32449..32670)
                     /locus_tag="VQ865_001092"
     CDS             complement(32449..32670)
                     /locus_tag="VQ865_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135438.1"
                     /translation="MSFYGLFYNGIAITPNTYLSAWFVNFIAALPLNFLIVEPIARFI
                     LSSFQKPFTGEEVEEVEDFQDDDEIPTII"
     gene            complement(33149..33358)
                     /locus_tag="VQ865_001093"
     CDS             complement(33149..33358)
                     /locus_tag="VQ865_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135439.1"
                     /translation="MLSVNTILEKFYKEHQVKPFISPERELDTWLLSPKPVPKRNMDL
                     LVDDSLAGDIILLWRIQFGTFTTET"
     gene            33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ865_001094"
     CDS             33528..33800
                     /gene="rpsP"
                     /locus_tag="VQ865_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002884675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HET3135440.1"
                     /translation="MAVKIRLTRMGSKKKPFYRINVADSRSPRDGRFIETVGTYNPLV
                     AENQVTLKEDRVLAWLANGAQPSDTVRNILSKEGVLKKFHDSKFSK"
     gene            33820..34059
                     /locus_tag="VQ865_001095"
     CDS             33820..34059
                     /locus_tag="VQ865_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HET3135441.1"
                     /translation="MDTIENLIIAIVKPLISQPDALTIKIEDTPEFLEYHLNLDQSDV
                     GRVIGRKGRTISAIRTIVYSVPTEYKKVRIVIDEK"
BASE COUNT        10380 a         6357 c         7396 g         9969 t
ORIGIN      
        1 tcttctttaa ttgatttcat attactattg tataatgatt tttgatttta gtttagtatt
       61 atcgtagaaa atggactcgg tgctatggat acaccggatg agaatggtta tgtagcagat
      121 gactatcgga ttacttactt agaggcccac atcaaggcca tgcgagatgc catttaccaa
      181 gatgggattg acttgcttgg ttatacgact tggagctgta tcgatccggt ttcagctggc
      241 acaggggaaa tgaataagcg ctatggcttt atctatgtag atcgagataa tgtaggaaat
      301 gggactctca aacgtagcaa gaagaagtcc ttctattggt acatgtcatt tatagcaatg
      361 gtgtaagcat cgagtagagc acatttgttt actattttta taaaatcttc tccctgcttt
      421 ataagatgta aaaaagagtt caaatggaac tctttttttg ctataatgag gggagaaaaa
      481 tcagacagga gattaagatg tcagaaccat tatttttaca atcagttatg caagaaaaaa
      541 tctggggtgg taccaagcta cgtgatgagt ttggctacga catcccaagt gaaaaagtcg
      601 gagagtactg ggctatctca gctcatctaa atggtgtttc taaagttgcc aatggtcgtt
      661 acgagggaac agatcttgct actttgtatg cggaacaccg tgaattattt ggcaatcgtc
      721 cggaacctgt atttccactt ttgaccaaga tcctcgatgc caacgactgg ctcagtgtcc
      781 aagttcaccc agacgatgct tatggactcg agcatgaagg cgaacttgga aaaacagaat
      841 gttggtacat cattgcagca gatgaaggtt cagagattat ctacggtcac aatgccaagt
      901 caaaagaaga actccgccag caaatcgagg ataagaactg ggatgcgctg ttgacaaaag
      961 tgccagttaa agcaggagat ttcttctatg taccaagcgg taccatgcac gctatcgggg
     1021 cgggtatctt gattcttgaa acccagcagt ctagcgatac cacttaccgt gtctatgact
     1081 ttgaccgtaa ggatgacaag ggcaatttac gtgaacttca ccttgaaaaa tctatcgatg
     1141 tcttgaacat tggtgaaccc gcaaatagcc gtccagtgac aatcaaagca gatgatctac
     1201 gttccactct ccttgtatcc aatgatttct tcgcagttta caaatgggaa attactggaa
     1261 aagttaactt tgaaaagaca gctgactaca gcttgttgag tgtcttggct ggtcaaggtc
     1321 aactaactgt tgacgggaaa aactatccaa tccaaaaagg gagacacttt atcctaccaa
     1381 gtgatgttga agcttggact ctggaagggc aagatttaga attaattgtt agtcatccat
     1441 aaaaaagaaa gggcctgagt tcattactca agtccttttg attacataaa ttgggcgatg
     1501 aagaccacga tgatgattgg aatgacggaa cgaagaaacg aagaaggaag agccagactt
     1561 ggaacagtcc ttgtttccat gctctttcat cgagatggag ttcctccatt gcaagagcct
     1621 ttttaaagat atagcctgta aaaagtgaaa ggaagagagc tccaaatggc atgaggagat
     1681 tggaaaccaa gaagtccata gcgtcaaaga aggtcttacc aaaaatgtga acatccgcca
     1741 tgacaccgta agatagggct gaaggaatgc caaagacaaa ggtcagaatt tctaaaataa
     1801 cactccattt agcacgcttg ctgttgtcct gattggtgat attgtctaca ttgatttcta
     1861 gcatcacgac agaagaagtg acagtcgcaa agaggaagag gacgtagaaa atggttccaa
     1921 aaggcatctt gtcaaagagt tgaggcaaga cgataaagag caggctgggt cccccttcag
     1981 actggatatt gaagggggat cgagcttgga aaatggctag acctgccatg atggatatcg
     2041 agatattcat ggctacgatg gagattcctg actggactag attggttttc ttgtccaagt
     2101 aagaagcata ggtcaacatg actgtaaccc ctagtgagag ggcaaagaaa gattgtccca
     2161 gagcatagag gagaccagcg ctagtcagtt ttgaaaagtc tggtttgagg aagtaaagaa
     2221 ccccttccat ggcatttggc aaactgagag agcgaccgat gataaaaaca aagacgataa
     2281 agagcagggg catcatgact ttcgaagctc tttcaatctc tttttgaacc ccacgtgata
     2341 caatgaagat attcaatagg ataaaggccg cttgagctcc tagggcaatg gctggatttg
     2401 aaatgattga agtaaataac tgagcataat cacccgttcc accaagttgg aacaatttcc
     2461 caaactcaat acctagatag actagaatcc atcctccgat aacactgtaa aaagataaga
     2521 ggataaagag ggcaaaggcg ccaatccaac cgataaagtt gtacttgtta ttcttgccca
     2581 gttttccaaa ggttttgata gcggaaacgc cagcactacg gccaagggca aactcagcca
     2641 gcaggagagg gaaaccgatt aaaatagtgg aaatgagaaa gattagtaaa aagcctccac
     2701 cgccattagc agcagtcatg tagggaaact tccaaacgga accaagcccg atggccagcc
     2761 agcagatgct agaataaaac caagtttcga cccccattgt gatttttctg acatagttaa
     2821 actctgatct cctttttcaa aataagaaaa agctacttga gttgtcaaat agccttctgt
     2881 ttgattgata gacttgacta tcctatcatg ttttctaagg tctgtcaaga aaatcatttt
     2941 caagttttca cacctttctc aaaaaagtta aaaaattttc tcaaaaacgc ttgactctga
     3001 cctaagggga ggggttatac tatcattgta aggaggaaat catgtaccat ataaaagaag
     3061 ctgcgcagct ttcaggtgtc tctgtcaaga ccctgcatca ctatgacaag ataggactct
     3121 tggtcccctt aaagtcggaa aacggctatc gaacctacag tcaagaggat ttggaacgcc
     3181 ttcaggtcat tctttactac aaatatctag gcttttcttt agagaaaata gcagagctgt
     3241 taaaggaaga aaggacagat ttattgcccc atttgactag gcagttggac tatctaactc
     3301 gcgaaaggca acatctggat accttgattt ccaccttgca aaaaactatt caagaacaaa
     3361 aaggagaaag aaaaatgacc attgaggaaa aattcacggg atttagctat caagacaatc
     3421 aaaaatacca ccaagaagcg gtagagaaat atggtcaaga agtcatggga caagcgctcg
     3481 aacgccaaaa aggtcacgaa gacgaggcta cggccgcctt taaccaagtc tttcaaactt
     3541 tggcacaaaa tcttcaagtt ggtttacctg caacagcaac cgaaaaccag gagcaagcag
     3601 ccaagctctt gcaagccatt cgcacttatg gatttgactg ctctattgag gtattcggtc
     3661 atatcggtaa aggttacgtc tacaacccag agtttaagga aaacattgac aagtttggtt
     3721 ctgaaacagc ccagtacacg tcagatgcca ttgcggctta cgttcagaca aatgcagaat
     3781 aaataggcta ggaatttcct agcctatttt ttacttcaaa tcataaagcc agtcgtcacc
     3841 gtttttgtag taaaagaatt cactgagatc ttcttctaga aacacacgaa gcatatcaga
     3901 catatcatcg gttgcaagtt ttagatgaga aagattttca aagtcctccc accaaacttt
     3961 cccttcgtct gaagactgga gttcaccagt aaagtgttct gtcttgtaaa aaaggacgac
     4021 ataacgataa tccttgtcgt cataccagtt tttgatacca cagagttggg gtttggaaat
     4081 gatcagacca gtttcttctt tcacttcacg aatgacagca tcgacaaagg attcgccacg
     4141 ttcaacatga ccaccaggaa aagtaatgcc agaccagtcg ggactaactc ggtcttggac
     4201 caggacctta tctccgtttt taatcataca catgttaaca aattcgactg cctctcttct
     4261 gttcattctt cacaaccttt aatctttaat cataatgcag acttcccgcc acccagccgg
     4321 tacagagggc agaagtgatg ttaaagccac ccgtgtgggc attgatatcc ataacttcgc
     4381 ctgcaaagtg gaggccaggt accagcttac tttcaagggt tttaggattg atttccttga
     4441 gactgactcc acccttggta acaaaggact ttgcaaggga catttttcca gttacaggaa
     4501 ttttaagttc tttaatggac tggacaagtt gttctcgttc cttttcagtc agttgtttga
     4561 ctttttcagg atatccttgt acaaaaaatt cggccaagcg ttctggtaac aaggttttta
     4621 aagcgttttt caaggatttt tcccgatttt cttctagaaa tgtaaccaag tccttctcag
     4681 aaagttgagg caaaacatcg agtgagagaa cctccccacc tttgacaaag ctagacatgc
     4741 gtagggcagc aggacctgac aaaccaaagt gggtaaagag taaatcatga gtgatgacat
     4801 gcttaccata acttagggtc acctcgtcca gagaaatccc ttgtaaggct ttatgtggaa
     4861 aatctgttaa taaaggactt tcagcagcct caagatcggt gatggtatgc ttaaaatggc
     4921 gagcaatctc gtgaccaaaa ccagtcgaac cagtcgaagg ataagactta ccacctgttg
     4981 tgacaatgag tttctcacaa gtgaaggttt gatccgctga cttaaggaca aactggttat
     5041 ctactttttt aacagaaacg atttctattt gagtagcaac ttgaccacct agttcggtga
     5101 ttttcttttc caaagcttcg ataatagtcc gagacttgtc actggctgga aagacgcgtc
     5161 cgtggtcttc gaccttaagt ttaacaccat tttctgtaaa aaagttgatg atgtcatgat
     5221 tatcgaactg ggagaaaaca ctgtaaagaa agcgtccgtt tccaggaatt ccagctagca
     5281 ggttgtctaa gctaccattg ttggtcacat tgcaacgtcc cccaccagtc ccagctaatt
     5341 tttttccaag tttccgattt ttttcgatga ggagggtttt ctgtccataa aagctactgg
     5401 aaatcgtagc catcatacca gcaggtcccc caccgatgac aatagtatca aaatgtttca
     5461 tagctctatt gtaccacaaa aaaacaagag atgatggtca cctcttgtca agaatgcaat
     5521 taatcaattt catagcccat cagcaaaccg ccctcttctg catagaaact gcagagacca
     5581 gaggttggta gaattttaat atccgcttgt gggaaggttt cacggattcg ctctgagagc
     5641 tgttgacaac atttttcgtt attgcgttgg gccatgacaa tacggccacc agcatatcca
     5701 gcttttacta actcatcata ggcagcttga actgatttct ttgatcccct tgctttttgt
     5761 agcaattcga gagttccagt ttcactagct tttccgacca tacgaatgtt gagaaggcca
     5821 acgaccgtac cgataagctt gctcaaacgg ccgttcttca ccaagttatc gactttggct
     5881 aggacaaaga gcaacttagt tttttcttga taggcagtga tagcttcaac cacttcttca
     5941 aaagacaagc cctggtcaat caagtcattc aatttttcta cgagtaggtc aacttcacca
     6001 ccagcagata aactatcaat cacatgaatc ttagtgtcag gatggtcttc cagataaata
     6061 ttctttgcta gttgagcact attgtgactg ccagaaaggg tacctgtgat ggttactagg
     6121 aaaatgtttt tggcaccttc aaatgctcgc aaatagtcat ctgggcttgg acaagctgat
     6181 tttgaagctt ctgcagttgc atacatggtt tccatcattt ggtcaatatc gagactggcg
     6241 tcatcaacaa agacctgatc agctacttga atggttaagg ggacacttac aaaggttgtg
     6301 ttaatagctg gtgttggcag ttgacgataa tcacaaccag agtcagcaat aatcttccaa
     6361 gtcatagaaa ttctccatct ttgtcagtta tacattgaca aaggttctgt ctttttttac
     6421 aattatatca tgaaaactct tgaaacaaaa gcatcatccg tctgttgtga caagtagaaa
     6481 gaaaatgtta tgtctgaacg tagaatctct gaaaagtctc ttgaaaatct cagaaaatca
     6541 aaccaagaat ccaatttatt aaccagagaa gccattgaaa cagccctctt gcaactcttg
     6601 gaaaaaaagg agctgaccaa gattagtatt tctgaattgg tcaaacgtgc aggtgtttcg
     6661 cgtgcggcct tttatcgcaa ttatgactcc aaagaggaaa ttttagagag cgtctttaaa
     6721 cgaactgtcc acaatattat ggaacagctg catcattacg atttaaagac agacctttat
     6781 ttggtttggg ttcacctttt ccgggaggcc agaaaggaag ctagagtaat tcaattggcc
     6841 ttggattacc atctggaaaa aatctttgtc caagccatgc aggaatttct agaaaaatac
     6901 catgggaaat caaaaggtgt cagctcttat cttcattcct tctggagctc agccatcgtc
     6961 tctgtccttc taaaatggat caaggatggc atgaaggtac cagctgaaaa gattgcagat
     7021 ttaggtttac cattttttaa aaaatagaga aaaaggagaa aagagatgac tgaaaaaaga
     7081 ctggcctggg atgagtattt tgcagcccaa gccctactaa ttgcgaatcg ttccacttgt
     7141 aaacgtgcta aagtgggcgc gattctggta aaagataata aggtaatttc cactggttac
     7201 aatggttcgg tgtcagggac tgagcattgt attgatcacg aatgtttggt cattgaaggc
     7261 cactgtgttc gcacccttca cgctgaggtc aatgctatcc ttcaaggtgc tgagcgtggt
     7321 gttcccaaag gctttacagc ctatgtaacc cattttcctt gtctcaactg tacaaaacaa
     7381 ttgcttcagg tcggctgcaa gcgcgtggtt tatatcaacc agtaccgaat ggacgactac
     7441 gcccaatacc tttatcaaga aaaagggaca gaattgaccc atttaccact tgagacagta
     7501 cagacagctc ttaaagaggc tgatctaatg taaaaattat caaaaataaa tggtttagaa
     7561 agatttttaa accgtttttt ggtataatga gaagaataaa ttgaaagaag gaattccaaa
     7621 aatgggaaaa attgaagtta ttaatcaccc actgattcaa cacaaattgt caatcttgcg
     7681 tcgtatagat acttctacaa aagcttttcg tgagctagta gatgagattg caatgttgat
     7741 ggggtatgaa gtacttcgtg atcttccact agaagatgtg gaaatcgaaa caccaattac
     7801 aaaaacagtt caaaaacaat tggcaggtaa gaaattggcc atcgtcccaa tcttgcgtgc
     7861 aggtatcggg atggttgatg gtctcttgag cttggttcca gctgctaaag ttggccacat
     7921 cggtatgtac cgtgatgaag aaacacttca accagttgaa tacttggtga aattgcctga
     7981 ggacattgac caacgtcaaa tttttgtagt agacccaatg ttggcaacag gtggctcagc
     8041 aatcttggct gttgattctc ttaaaaaacg tggcgcatca aatatcaaat ttgtctgcct
     8101 tgtatctgct ccagagggtg taaaagccct tcaagaagct catccagatg tagaaatctt
     8161 tacagcagcc ttggatgaac gtttgaacga acacggttat atcgttccag gtcttggaga
     8221 tgctggagac cgcttgttcg gtacaaaata agatcgaaaa gaagaatgac ttggaaaagt
     8281 atttccagtc acgaaaggag gttgggtttt tgtttctgtc taatgaaagc agagcaaaaa
     8341 tttgaccttt tttgaccaag atattataat agtcttatct tcagtcattt gaccaacaaa
     8401 attaaaactc aaaaggagaa atgaatgatt cctgtagtta ttgaacaaac aagccgtgga
     8461 gaacgttctt acgatattta ctcacgtctt ctcaaagacc gcatcattat gctgacaggt
     8521 ccggttgaag acaatatggc taactctgtt attgcccaat tgcttttctt ggatgcccaa
     8581 gatagtacaa aagatattta cctttatgtc aatacaccag gtggttctgt ttcagctggt
     8641 ttggcaatcg tagataccat gaactttatc aaggcagatg tccaaaccat tgttatggga
     8701 atggctgcat ctatggggac tgtcatcgca tcaagtggag caaaaggcaa acgtttcatg
     8761 cttccaaatg ctgaatacat gattcaccaa ccaatgggcg gtacaggtgg tggtacccaa
     8821 caaactgata tggctatcgc tgcagaacac ttgctcaaaa ctcgtaatac cttggaaaaa
     8881 atcttggctg aaaattcagg tcagtcaatg gaaaaagtcc atgcagatgc agaacgtgat
     8941 aactggatga gcgcccatga aacacttgaa tatggcttta ttgatgaaat tatggccaac
     9001 aattcattga actaatgatg atagaaggca aactcgactg ggtttgcttt ttttggtata
     9061 atagggagag atttcttaga aagaggattt atcatgtttg aaaaagtcaa tcgctctggc
     9121 ttgattatct atctttacta taatcgtgat gccaaaaaac tgcaggatta tggagatatt
     9181 acctatcatt ccaagaaaca tcgttactta caactctatg ttccaactca agaagtggag
     9241 caattggtcg gacgcttgag caaggaaaaa tttattaaaa aagttagggt ttgtcatatc
     9301 caagagttgg aaacaccctt tgtgggcaat ctttatcgat aggaaaacgt tatcatcgaa
     9361 aaagttcaag gaaaacattg acaattttct gataattcgg tatattctta acagactatt
     9421 taagaaataa ggagacaaaa agatgaagaa aaaatttgcc ctatcgtttg tggcgcttgc
     9481 aagtgtagca cttcttgcag cctgtggaga agtgaagtct ggagcagtca acactgctgg
     9541 taactcagta gaggaaaaga caattaaaat cgggtttaac tttgaagaat caggttcttt
     9601 agctgcatac ggaacagctg aacaaaaagg tgcccaattg gctgttgatg aaatcaatgc
     9661 cgcaggtggt atcgatggaa aacaaatcga agtagtcgat aaagataata agtctgaaac
     9721 agctgaggct gcttcagtta caactaacct tgtaacccaa tctaaagtat cagcagtcgt
     9781 aggacctgcg acatctggtg cgactgcagc tgcggtagcg aacgctacaa aagcaggtgt
     9841 tccattgatc tcaccaagtg cgactcaaga tggattgact aaaggtcaag attacctctt
     9901 tattggaact ttccaagata gcttccaagg aaaaattatc tcaaactatg tttctgaaaa
     9961 attaaatgct aagaaagttg ttctttacac tgacaatgcc agtgactatg ctaaagggat
    10021 tgcaaaatct ttccgcgagt catacaaggg tgaaatcgtt gcagatgaaa ctttcgtagc
    10081 aggtgacaca gacttccaag cagcccttac aaaaatgaaa gggaaagact ttgatgctat
    10141 cgttgttcct ggttactata atgaggctgg taagattgta aaccaagcgc gtggcatggg
    10201 aattgacaaa ccaatcgttg gtggtgatgg attcaacggt gaggagtttg tacaacaagc
    10261 aactgctgaa aaagcatcaa acatctactt tatctcaggc ttctcaacta ctgtagaagt
    10321 ttcagctaaa gctaaagcct tccttgacgc ttaccgtgct aagtacaatg aagagccttc
    10381 aacatttgca gccttggctt atgattcagt tcaccttgta gcaaacgcag caaaaggtgc
    10441 taaaaattca ggtgaaatca aggataacct tgctaaaaca aaagattttg aaggtgtaac
    10501 tggtcaaaca agcttcgatg cagaccacaa cacagtcaaa actgcttaca tgatgaccat
    10561 gaacaatggt aaagttgaag tagcagaagt tgtaaaacca taatagaaaa atgttgaaat
    10621 agggaatgag cctttgactc actccctgtt tcgatattta atactcttcg aaaatctctt
    10681 caaactgcgt caacgtcgcc ttggattata tatgtgactg acttcgtcag tcttatctac
    10741 aacctcaaag cagtgctttg agcaacctgc ggctagtttc ctagtttgct ctttgatttt
    10801 cattgagtat aagaacctat caaaaagtga gggaaacccc tcggaattat aaatagaaag
    10861 agtgaatctt atgctccaac aactcgtaaa tggtttgatt ctaggtagtg tttacgcgct
    10921 gttagcccta ggatatacca tggtttacgg aattatcaag ctcatcaact tcgcccatgg
    10981 tgatatttat atgatgggag cctttatcgg ttatttcttg atcaattctt tccaaatgaa
    11041 tttctttgta gcgcttattg tagctatgct agcgacagct attcttggtg tcgtgattga
    11101 gtttcttgct taccgacctt tgcgccactc tactcgtatt gctgttttga ttacggctat
    11161 tggggtttct ttcctattgg agtatggaat ggtctatctg gttggtgcca atacccgtgc
    11221 cttccctcaa gcgattcaaa cagttcgata tgatttggga ccaattagct taacaaatgt
    11281 gcagttaatg attttgggca tttccttgat tttgatgatt ttgttacaag tcattgtcca
    11341 aaagactaag atggggaaag ccatgcgtgc agtatcagta gatagcgacg cggcgcaatt
    11401 gatggggatc aatgtaaacc gtacgattag ctttaccttc gctttgggtt ctgctcttgc
    11461 gggtgcggct ggtgttctga ttgctcttta ttataactct cttgagcctt tgatgggggt
    11521 tactccaggt cttaaatctt tcgttgccgc agtacttggt ggtatcggaa ttattcctgg
    11581 tgcggctctt ggtggctttg tgattggtct attggaaacc tttgcgactg cctttgggat
    11641 gtcagatttc cgtgatgcca ttgtttatgg aatcttgttg ttgatcttga ttgtccgccc
    11701 agctggtatc cttggtaaga atgtgaaaga gaaggtgtaa acgatgaagg aaaatttaaa
    11761 agttaatatt ctatggttac tccttttgtt agctggctat agcttgatta gtgtactggt
    11821 ttcagtcgga gtacttaatc tattctatgt acagatttta caacaaattg gaattaatat
    11881 tattttggct gttggtctca acttaatcgt tggtttttca ggacaatttt cacttggtca
    11941 tgctggtttc atggcgattg gtgcctatgc agcagctatt attggttcta aatcaccaac
    12001 ctacggtgcc ttctttggag ctatgcttgt aggggctttg ctttcaggag cagttgcctt
    12061 acttgtcggc attccaacct tgcgcttgaa gggggactat cttgcggtag caactctagg
    12121 tgtttctgaa attatccgta tctttatcat caatggtgga agccttacaa atggtgcggc
    12181 aggtatttta gggattccta actttacaac ttggcaaatg gtttacttct ttgtcgtgat
    12241 tacaaccatt gcaaccttga acttcttgcg tagcccaatt ggtcgttcaa ccctctctgt
    12301 tcgtgaagat gaaatcgctg ctgagtcagt tggggttaat acgactaaaa ttaaaatcat
    12361 cgcttttgtc tttggtgcca ttactgcaag tattgctggg tcacttcagg caggatttat
    12421 cgggtctgtt gtaccgaaag attacacctt catcaactca atcaacgttt tgattattgt
    12481 tgtatttggt ggactcggtt ccattacagg tgcgattgtt tcggctattg ttctgggaat
    12541 tttaaatatg cttctccaag atgttgctag tgtgcgtatg attatttacg ctttggcctt
    12601 ggtattggta atgattttca gaccaggtgg actccttgga acgtgggaac tgagcctatc
    12661 acgtttcttt aaaaaatcta agaaggagga acaaaactaa tggcattact tgaagtaaaa
    12721 cagttaacca aacattttgg tggtctaaca gctgttggag atgtgactct tgaattgaac
    12781 gaaggggaac tggttggatt aatcggtcca aacggagctg ggaaaaccac ccttttcaac
    12841 cttttgaccg gtgtttatga accaagcgag ggaacagtaa ccctagatgg tcaccttttg
    12901 aatgggaaat caccttataa gattgcctct ttgggacttg gacgtacttt ccaaaatatc
    12961 cgtctcttta aagatttaac agttttagat aatgttttga ttgcttttgg aaaccatcac
    13021 aaacagcatg tttttactag tttcttacgc ttaccagctt tttacaagag tgaaaaagaa
    13081 ttaaaggcta aagctttgga attgttgaaa atctttgatt tagatggtga tgcagagact
    13141 cttgctaaaa atctttccta cggacaacaa cgtcgtttgg aaattgttcg tgcccttgct
    13201 acggaaccta aaattctctt cttagatgaa ccagcagcag gtatgaaccc acaggaaaca
    13261 gccgaattga ctgagttaat tcgtcgtatc aaagatgaat ttaagattac aatcatgttg
    13321 attgaacacg atatgaatct ggtcatggaa gtaacagaac gtatctacgt acttgaatat
    13381 ggccgtttaa ttgctcaagg aactccagac gaaattaaga ccaataaacg cgttatcgaa
    13441 gcttatctag gaggtgaagc ctaatgtcta tgttaaaagt tgaaaatctt tctgtgcatt
    13501 acggtatgat ccaagcagtc cgtgatgtaa gctttgaagt taatgaagga gaagttgttt
    13561 cccttatcgg tgccaacggt gcaggtaaga caactattct tcgcaccttg tcaggtttgg
    13621 ttcgaccaag ttcaggaaag attgaatttt taggtcaaga aatccaaaaa atgccagctc
    13681 agaaaatcgt ggcaggtggt ctttcacaag ttccagaagg acgccacgtc tttcctggct
    13741 tgactgttat ggaaaatctt gaaatgggag ctttcttaaa gaaaaatcgt gaagaaaatc
    13801 aagcaaactt gaagaaggtt ttctcacgct ttcctcgtct tgaagaacgt aagaaccaag
    13861 atgcagctac tctttcagga ggggaacaac aaatgcttgc catgggacgc gctcttatgt
    13921 caacaccaaa acttcttctt ttagatgaac catcaatggg acttgcccca atcttcatcc
    13981 aagagatttt tgatatcatt caagatattc agaagcaaga aacaaccgtc ctcttgattg
    14041 aacaaaatgc caataaagca ctcgcaatct ctgaccgagg atatgtattg gaaacaggaa
    14101 aaatcgtcct atcagggaca ggaaaagaac tcgcttcatc agaagaagtc agaaaagcat
    14161 atctaggtgg ctaaaacaat ccagtggatt gttttagtcg gcagatgaag attacgaagt
    14221 aatcatcaat atagtccggg ggaccttttt agtcggtaga ttgagattgc aaacaaatat
    14281 gcatctacat tgaaagctta atttctaata attgaaaaaa tcgaatgaaa aatttcttac
    14341 cttcattcac agagctctat ttcagagctc tttttgctag cttattcata cttttctgaa
    14401 tttcgaaaaa gaaatgtaag cgtttgatag atttacaaaa agattgtata atagggataa
    14461 gaatagaaaa ggagaagtct catggcagtt aaagatttta tgacccgcaa ggtagtttat
    14521 attagtccag atacaacagt atctcatgca gcagatttga tgagagagca aggtttgcac
    14581 cgtctgcctg ttatcgaaaa tgatcaatta gttggtttgg tgactgaggg aaccattgca
    14641 caagcaagtc catctaaagc aacaagtctt tctatctatg agatgaatta tcttctgaat
    14701 aagacaaaag taaaagatgt catgattcgc gatgttgtca ctgtctcagg ctatgctagt
    14761 ctagaagatg caacttatct gatgttgaaa aataagatta gtattctccc tgtcgtagat
    14821 aaccatcaag tatacggagt tattactgac cgtgacgttt tccaagcctt tcttgaaatt
    14881 gcaggttatg gcgaagaagg gattcgtgta cgctttgtta cagaagatga agttggtgtt
    14941 cttggaaaaa ttgtttcttt gattgtagaa gaaaatttga atatctccca tacagtcaat
    15001 attccgcgta aggatggtaa ggtgattatc gaagtgcaaa tcgatggatc aattgattta
    15061 ccagccttga aagaaaaatt tgaagcaaat ggtattcaag tggaagaaat cgctcgcact
    15121 tcagcaaaag tcttgtaaga agggaagccc aaaggcttct tttttcatga aaaggggatt
    15181 agagcaaaag atggaaagaa atgataaaat atgctataat gaaataatgt aaaaaaggag
    15241 tatttatgga catttcagta attcgtcaga aaattgacgc aaatcgtgaa aaattagctt
    15301 ctttcagggg gtctctttga cctcgaaggg ctagaggaag agattgccat cttggaaaac
    15361 aagatgacag aacctgattt ttggaacgat aatattgcgg cccaaaaaac gtcgcaagaa
    15421 ttgaatgaat taaaaaacac ttacaatacc ttccataaga tggaagagtt gcaggatgaa
    15481 gtcgaaattt tattggattt tttggctgaa gacgagtcag tgcatgatga actggtagcg
    15541 cagttagccg aacttgataa gataatgacc agctacgaga tgactctact attgtcagaa
    15601 ccttatgacc acaacaatgc catcttggaa atccatccag gttctggtgg tactgaggcg
    15661 caggactggg gtgatatgtt gcttcgtatg tatactcgtt atggtaatgc taaaggcttt
    15721 aaagtggaag tgttggatta ccaagcaggt gatgaggctg gtattaagtc ggtaacttta
    15781 tcatttgaag ggcctaatgc ctatggtctc ctcaagtcag aaatgggtgt tcatcgctta
    15841 gtgcgaatct caccatttga ctctgccaaa cgtcgccata cctctttcac atctgtagaa
    15901 gtgatgccag aattggatga tactattgaa gtggaaatcc gtgaagatga tatcaagatg
    15961 gataccttcc gttcaggtgg tgccggtgga caaaacgtca ataaggtttc aacaggtgta
    16021 cgtttaaccc acattccaac tggaattgtt gtccaatcaa cagtggatcg tacccagtat
    16081 ggaaatagag atcgtgccat gaagatgttg caggctaagc tctatcaaat ggagcaagat
    16141 aagaaggctg cggaggtaga ttctctcaaa ggtgagaaaa aggagatcac ttggggaagc
    16201 caaatccgtt cttatgtctt cacgccttat actatggtaa aagatcaccg aactagcttt
    16261 gaggttgctc aggtagataa ggttatggat ggggacctag atggttttat cgatgcttat
    16321 ctcaagtggc gaattagcta agatagaaag gaactcacat gtcaattatt gaaatgagag
    16381 atgtcgttaa aaaatacgac aacggaacga ctgctctacg cggtgtttcg gttagcgttc
    16441 aaccggggga atttgcttac atcgtaggac cttcaggagc agggaagtca acttttattc
    16501 gttctctgta tcgtgaagta aaaatcgata aaggaagtct atcagttgct ggttttaatc
    16561 tggttaagat caaaaagaaa gatgtcccgc ttctacgtcg tagtgttggg gttgtcttcc
    16621 aagattataa attgttacca aagaaaactg tctatgaaaa tattgcttac gctatggaag
    16681 taatcgggga aaatcgccgt aatatcaaaa gacgagtgat ggaagttttg gacttggttg
    16741 gattgaagca taaggttcgt tctttcccaa atgaactctc aggtggggag cagcagcgaa
    16801 ttgcgattgc gcgtgcaatt gtaaataatc ccaaagtatt gatagctgat gagccaacag
    16861 gaaatctgga tccggataat tcatgggaaa ttatgaatct cttggaacgg attaacctac
    16921 aagggacaac tattttgatg gcgactcata atagccagat tgtaaatacc ttgcgccacc
    16981 gtgtcattgc cattgaaaat ggccgtgtcg ttcgtgacga atcaaaagga gagtatggat
    17041 acgatgatta gtagattttt tcgccattta tttgaagcct taaaaagttt gaaacgaaat
    17101 ggttggatga cagtagctgc tgtcagttca gtcatgatta ctttgacctt ggtggcaata
    17161 tttgcatctg ttattttcaa tacagcgaaa ttagctacag atattgaaaa taatgtccgt
    17221 gtagtagttt atatccgaaa ggatgtggaa gataatagtc agacaattga aaaagaaggt
    17281 caaactgtta caaataatga ctaccacaag gtatatgatt ctttgaagaa catgtctacg
    17341 gttaaaagtg ttaccttttc aagtaaagaa gaacaatatg aaaaattaac cgagataatg
    17401 ggagataact ggaaaatctt tgaaggagat gccaatcctc tctatgatgc ctatattgta
    17461 gaggcaaaca ctccaaatga tgtaaaaact atagccgaag atgctaaaaa aattgaaggt
    17521 gtctctgagg ttcaagatgg cggtgccaat acagaaagac tcttcaagtt agcttcattt
    17581 atccgtgttt ggggactagg gattgctgct ttgttaattt ttatcgcagt tttcttgatt
    17641 tcaaatacca ttcgtattac cattatttcc cgcagtcgcg aaattcaaat catgcgcttg
    17701 gttggagcta aaaacagtta tatccgtgga ccgttcttgt tagaaggagc ctttatcggt
    17761 ttattgggag ctatcgcacc atctgttttg gtctttattg tttatcaaat tgtttaccaa
    17821 tctgtcaaca aatcgttggt agggcaaaat ctatccatga ttagtccaga tttatttagt
    17881 ccgttgatga ttgccctact atttgtgatt ggggttttca ttggttcatt gggatcagga
    17941 atatccatgc gccgattctt gaagatttag gtaaaatagc tgcttttatg aggagattgt
    18001 aaaatctcct tttttgctac aagagttttt gaaaagagat gcgtagaaga aaagagcttc
    18061 caaagaagtc ccccagagaa gacttcttga tggctaattt gaacttgaaa tttggcgcac
    18121 tagaaatttt ttagaaaaaa gtgtaatttt tttataaaag cctttacaaa aaaaattaaa
    18181 gtggtataat taaatcatag aaggtgcaaa cgttttcgta aaacgtttgc ctaaataaaa
    18241 ataaaggaga tttgaatgat gaaagataca ttcaaaaatg tcttgtcttt cgaattttgg
    18301 caaaaattcg gtaaggcttt gatggtagtt atcgcggtta tgccggctgc tggtttgatg
    18361 atttcaatcg gtaagtctat cgtgatgatt aacccaacct ttacaccact tgtcatcaca
    18421 ggtggaattc ttgagcaaat cggttggggg gttatcggta accttcacat tttgtttgcc
    18481 ctagccattg gaggaagctg ggctaaagaa cgtgctggtg gtgctttcgc cgctggtctt
    18541 gccttcatct tgattaaccg tatcactggt acaatttttg gtgtatcagg cgatatgttg
    18601 aaaaatccag atgctatggt aactactttc tttggtggtt caatcaaagt tgctgattac
    18661 tttatcagtg ttcttgaagc tccagccttg aacatggggg tattcgtagg gattatctca
    18721 ggttttgtag gggcaactgc ttacaacaaa tactacaact tccgtaaact tcctgatgca
    18781 ctttcattct tcaacgggaa acgtttcgta ccatttgtag ttattcttcg ttcagcaatc
    18841 gctgcaattc tacttgctgc tttctggcca gtagttcaaa caggtatcaa taacttcggt
    18901 atctggattg ccaactcaca agaaactgct ccaattcttg caccattctt gtatggtact
    18961 ttggaacgtt tgctcttgcc atttggtctt caccacatgt tgactatccc aatgaactac
    19021 acagctcttg gtggtactta tgacatttta actggtgcag ctaaaggtac tcaagtattc
    19081 ggtcaagacc cactatggct tgcatgggta acagaccttg taaaccttaa aggtactgat
    19141 actagtcaat atcaacactt gttagataca gtacatccag ctcgtttcaa agttggacaa
    19201 atgatcggtt cattcggtat cttgatgggt gtgattgttg ctatctaccg taatgttgat
    19261 gctgacaaga aacataaata caaaggtatg atgattgcaa cagctcttgc aacattcttg
    19321 acaggggtta ctgaaccaat cgaatacatg ttcatgttca tcgcaacacc tatgtatctt
    19381 gtttactcac ttgttcaagg tgctgccttc gctatggctg acgtcgtaaa cctacgtatg
    19441 cactcattcg gttcaatcga gttcttgact cgtacaccta ttgcaatcag tgctggtatt
    19501 ggtatggata tcgttaactt cgtttgggta actgttctct ttgctgtaat catgtacttt
    19561 atcgcaaact tcatgattca aaaattcaac tacgcaactc cagggcgcaa cggaaactac
    19621 gaaactgctg aaggttcaga agaaaccagc agcgaagtga aagttgcagc aggctctcaa
    19681 gctgtaaaca ttatcaacct tcttggtgga cgtgtaaaca tcgttgatgt tgatgcatgt
    19741 atgactcgtc ttcgtgtaac tgttaaagat gcagataaag taggaaatgc agagcaatgg
    19801 aaagcagaag gagctatggg tcttgtgatg aaaggacaag gggttcaagc tatctacggt
    19861 ccaaaagctg acattttgaa atctgatatc caagatatcc ttgattcagg tgaaatcatt
    19921 cctgaaactc ttccaagcca aatgactgaa gcacaacaaa acactgttca cttcaaaaat
    19981 cttactgagg aagtttactc agtagcagac ggtcaagttg ttggtttgga acaagtaaag
    20041 gatccagtat ttgctcaaaa aatgatgggt gatggatttg cagtagaacc tgcaaatgga
    20101 aacattgtat ctccagtttc aggtactgtg tcaagcatct tcccaacaaa acatgctttt
    20161 ggtattgtga cggaagcagg tcttgaagta ttggttcaca ttggtttgga cacagtaagt
    20221 cttgaaggta aaccatttac agttcatgtt gctgaaggac aaaaagttgc agcaggagat
    20281 ctccttgtca cagctgactt ggatgctatc cgtgcagcag gacgtgaaac ttcaacagta
    20341 gttgtcttca caaatggtga tgcaattaaa tcagttaaat tagaaaaaac aggttctctt
    20401 gcagctaaaa cagcagttgc taaagtagaa ttgtaatata cttgaggttg gaagctgtat
    20461 tccaacctct tattttggga gaaaagaatg aaatttttaa cactcaatac tcacagttgg
    20521 atggagaaag aagcagagga aaaattccag attttgcttg aagatattct tgaaaaggac
    20581 tatgatttga tttgtttcca agaaatcaat caggagatga cctcgtcaga ggtggaggtt
    20641 aatgaccttt atcaagcttt gccagcagct gagcctattc accaagacca ttatgttaga
    20701 ctcttggttg aaaagttgtt agagcaaggg aaaaattact actggacctg ggcttataac
    20761 catatcggct atgaccgcta ccacgaaggt gtggctatct tgtctaaaac acctattgaa
    20821 gccagagaaa ttttggtttc agatgtggat gatccaacag actatcatac tcgccgtgtt
    20881 gccctagctg aaactgtagt cgatggcaag gagctagcag ttgccagtgt tcatctctct
    20941 tggtgggata aaggttttca agaagaatgg gcacgatttg aggctgtctt gaaaaaattg
    21001 aacaagccac ttttactagc tggagatttt aacaacccag caggtcagga aggttaccaa
    21061 gctattttag ctagtccatt aggcttacaa gacgcatttg aagttgctca agagaaaagt
    21121 ggtagctata ctgttccgcc tgaaattgat ggctggaaag ggaacactga accccttcga
    21181 atcgattatg tctttactac caaagagtta gcggtggaaa atttacatgt cgtatttgat
    21241 ggtaacaaga gtccacaagt gagtgatcac tatggcttga atgctatatt aaactggaaa
    21301 taataactga aaagaggttg gaactataaa attccagcct tttcttacta gagaagctac
    21361 tggaaatagc ctaaataagt gagactactg taatggaata aaatatggta taattgataa
    21421 gatagataga atcgaggatg ttatgtcatt tacgaaattt caatttaaaa actatattag
    21481 agaagccttg aaggagttaa aatttacaac tccaacagag gtgcaagaca agttgattcc
    21541 tattgttttg gcaggtcgtg acctagtagg agaatcaaaa acaggttcag gtaagactca
    21601 tactttcttg ttaccgattt ttcagcaatt agatgaagct agcgatagtg tacaagcagt
    21661 gattactgca ccgagtcgtg agttggctac tcaaatttac caagtagcgc gtcagatttc
    21721 agctcactca gatgtcgaag ttcgtgtggt taattatgtg ggtggtacgg ataaggctcg
    21781 ccagattgag aaattggcaa gcaatcagcc tcatattgtt attggaacac caggccgtat
    21841 ctacgacttg gttaaatctg gtgatttagc tattcataaa gccaagacat ttgttgttga
    21901 tgaagcagat atgaccttgg atatgggatt cttggaaact gttgataaga ttgctgacag
    21961 tcttccaaaa gacttgcaat tcatggtctt ctcagcgact atcccacaaa aactgcaacc
    22021 attcttgaaa aaatacttat caaatcctgt tatggagaaa attaagacca aaacggttat
    22081 ttctgacacc attgataatt ggttgatttc gaccaaggga catgataaga atgctcaaat
    22141 ttaccagttg actcagtcga tgcagccgta tttggcaatg atttttgtta acactaaaac
    22201 gcgtgctgat gaattgcatt catatctgac tgctcaaggc ttgaaggttg caaaaatcca
    22261 tggcgatatt gcccctcgtg aacgcaagcg aatcatgaat caggtgcaaa atctggattt
    22321 tgagtatatt gtcgcaacag atttggcagc acgtgggatt gacattgaag gtgtcagcca
    22381 tgtcatcaat gatgccattc cgcaagactt atcttttttt gttcaccgtg ttggtcgtac
    22441 tggacgaaat ggcctaccag gtacagctat taccctttat cagccaagtg atgactcgga
    22501 tatccgtgag ttggagaaat tgggaatcaa gtttagtcct aagatggtca aagacgggga
    22561 atttcaagat acctatgacc gtgatcgtcg tgccaaccgt gagaaaaaac aagataaact
    22621 tgatatcgaa atgattggtt tggttaaaaa gaaaaagaaa aaagtcaaac cgggttataa
    22681 gaagaaaatt caatgggcgg ttgatgaaaa gcgccgtaaa accaagcgtg ctgaaaatcg
    22741 cgctcgcggt cgtgcagagc gtaaagctaa acgccaaaca ttttaataga aattgttgga
    22801 gtactgagct ccaacttttt tatttatgag aacgaactat ctaaaccgaa acactacatt
    22861 aaagactgca aattgcgatt aaaaatggta taatgataaa gttatatagt cccgataaga
    22921 tggtaggtat ttattacgaa gagttttcct atcagtagtt tgcaattcgc aaagaatgac
    22981 ggcttcgagg tcgctcgtct ttctacggtt gccgccatac tgcggtcacc ctatgcgcct
    23041 tactagcttc agaaataaaa aagtatcgtt tttatttctg aagctagtaa ctcttagata
    23101 atggaaattc ctatcagtac tttgtaactc tataacaata ttttttaagg ggggacattt
    23161 ttatgtcaga acgtaaatta ttcacgtctg aatctgtatc tgaggggcat ccggataaga
    23221 ttgcagacca aatttcagat gcgattttgg atgctatttt agcaaaggat ccagaggcgc
    23281 acgttgctgc tgaaacagct gtatatactg gttctgtcca cgtttttggt gaaatttcta
    23341 caaatgccta tgtggatatt aaccgtgtgg ttcgtgatac cattgcagag attggttata
    23401 ccaatacaga atatggattt tctgctgaga cggtgggagt acacccatct ttggtggaac
    23461 aatctcctga catcgctcaa ggtgttaacg aagccttgga ggttcgtgga aatgctgatc
    23521 aagatccact ggacttgatt ggagcaggtg accaagggct catgtttgga tttgcagtag
    23581 atgaaacaga agagctcatg ccattgccaa ttgcactcag tcataaattg gttcgtcgtc
    23641 tggcagaact tcgtaagtct ggagaaatta gctatctccg tccagatgca aaatcacaag
    23701 ttacagttga gtacgatgaa aatgaccgtc cggtacgtgt agatacagtc gttatttcta
    23761 ctcagcatga tccagaggcc actaatgaac aaatccatca agatgtgatt gacaaggtca
    23821 tcaaagaagt tattccatct tcttatcttg atgataaggc aaaattcttt atcaatccga
    23881 caggtcgttt tgtaatcggt ggtcctcaag gggactcagg tttgactggt cgtaagatta
    23941 ttgtagatac ttatggtggc tactctcgtc atggtggtgg tgccttctct ggtaaagatg
    24001 cgactaaggt ggatcgttca gcctcttatg cggctcgcta tattgccaag aatatcgttg
    24061 cagcaggcct tgctaagaag gcagaagtgc agttggccta tgctatcggt gttgcgcaac
    24121 ctgtttctgt tcgtatcgat actttcggta caggaacagt agctgaaagt caacttgaaa
    24181 aagcggctcg tcaaatcttt gaccttcgcc ctgcagggat tatccaaatg ctggacctca
    24241 agcgtccaat ttaccgtcaa acatcggctt acggtcacat gggacgtaca gatattgatc
    24301 ttccatggga acgtttggat aaggtagatg ctttgaaaga agcagtaaaa taagatttta
    24361 agaggggaac gtcctctctt ttttatagtt tttaactata ctgggatact gttctgaaaa
    24421 tccattttgc gaaagtagag atttacatgt ataatggatt gaaactagaa tagtacacct
    24481 caacttctaa aacattgtta gaaatcgatt tgactgtcct gatcgatttc tcctgttctt
    24541 gtttcatttt actatatttc tttaaaaatg ataaaggttg agatttctcc tcgtaataga
    24601 taatcatggg gatatttcaa gccaaagttt tattcgttat cacttgacta ttgcaaggtt
    24661 ttctagatca acagagtcat ggaatggact catggttgag atttctcctt gttgcttgga
    24721 cttcattcaa aagtctgtta cccaagcctt gttcaaactt ccaatacact agctgtttcc
    24781 atagcatgac ttctgtacta gactttcttt tccgaataaa tagatagaac cacagaatct
    24841 agtaaaccta gaattaaaat tatggtataa tattagcaat aaaagaaatc tggaggatta
    24901 gaatcatggt atcaacgaaa acacaaattg ctggttttga gtttgacaat tgcttgatga
    24961 atgcagcagg tgtggcttgt atgacgatag aggagttaga agaggtcaaa aactcagcgg
    25021 caggaacctt tgttactaag acagcgacct tggacttccg tcaggggaat cctgagccac
    25081 gctaccaaga tgttccactt ggttccatca actctatggg cttgccaaat aatggcttag
    25141 actattattt ggattatctt ttagatttgc aggaaaaaga gtcgaaccga actttcttct
    25201 tatctctggt cggcatgtct ccagaggaaa cccatactat tttgaaaaaa gtccaagaga
    25261 gtgattttcg tggtctgact gagctaaatc tttcctgtcc aaatgttcca ggtaaacctc
    25321 agattgccta tgattttgag acaacagacc ggattttggc agaagtgttt gcttacttca
    25381 ccaaacctct tggaattaaa ttgccacctt attttgatat tgttcacttt gatcaagcgg
    25441 cagctatttt caacaaatat ccgctcaagt ttgtcaactg cgttaactct atcggaaacg
    25501 gcctctatat agaagacgaa tctgtcgtta ttcggcctaa gaatggtttt ggtggaattg
    25561 gtggagaata catcaaaccg actgctctag ccaatgttca cgccttttat caacgtttaa
    25621 atcctcaaat ccaaattatc ggaacaggtg gcgttctgac tggtcgagat gcctttgaac
    25681 acatcctctg tggagcaagt atggtgcagg tgggaacgac ccttcacaaa gaaggcgtca
    25741 gtgcttttga ccgcattacc aatgaactga aagcaatcat ggtggaaaaa ggctacgaga
    25801 gcttagaaga tttccgtggg aaattgcgct atattgacta aattaaatca aaaaatctga
    25861 agaaaggaga gacgatgcta gccattgaag aaagtcagaa gttgacttta tcaaatttac
    25921 cgagcctgag cctatttaca gggacagatc agggtcagtt tgaagtgatg aagagtcaaa
    25981 tgttgaaaca gattgggtat gattctgctg acctcaactt tgcctacttt gatatgaaag
    26041 aagtagttta caaggatgtg gaactggagt tggtcagcct tcctttcttt gcggatgaga
    26101 aaatcgtgat attagattat tttatggata tcacgactgc taagaaacgc tttttgacag
    26161 atgatgagct taagtcattt gaggaatacc ttgacaatcc ttctccaaca accaagttga
    26221 taatctttgc agaaggaaag ctggatagca aaagacggtt agtcaaatta cttaagcgtg
    26281 atgccaaggt cttcgatgca gtagaagtaa aagaacaaga attgcgccag tatttccaaa
    26341 agtggagtca gaaacaaggt ctgcagttta ccaatcattc ttttgaaaat ctcctcatca
    26401 agtcggggtt tcaatttagc gaaatccaga aaaatcttct ctttttacag tcctataagg
    26461 cgaattctgt tattgaggaa gaggatattg ttaacgcaat tcccaagacc ttgcaggaca
    26521 atatttttga tttaactcag tttattctga ctaaaaagat ggatcaggcg cgcgatttgg
    26581 tgagagactt gaccttgcaa ggggaagatg aaatcaaact gattgcagtc atgctgggac
    26641 aatttcggac ttttactcag gtgaagattt tggcggagtc tggccaaaca gaatcgcaga
    26701 ttgcaagtag tttaggtagt tatctgggac gtaacccaaa tccttatcaa atcaagtttg
    26761 cattaagaga ttcgagagga ctttctttga gctttctgaa gcaagctatt tcctatttga
    26821 ttgagacaga ctatcagatt aagacaggtc tttatgaaaa aggtttcctt tttgaaaagg
    26881 cactcttaca gattgctagt caggtcaatt gacatttgtt gaaactacaa cccgcgtcag
    26941 gattatcttg tcgtgggttt cttgctgatt tgcttatttt attagaaagt atgtcagtga
    27001 tttccttatc tataagcaaa aaacttgaaa aaagtgaatg tttgcgttat cattttcata
    27061 tagaaagaaa aagaggtatt acagatggct attatcttac cagaacttcc atatgcatac
    27121 gacgctttgg aaccatacat cgatgcggaa acaatgcatt tgcaccatga caaacaccat
    27181 caaacttatg tcaacaatgc caatgcagct ttagaaaaac accctgaaat cggtgaagac
    27241 cttgaagcct tgcttgctga tgtagaatct atcccagctg atatccgtca agcacttatc
    27301 aacaatggtg gcggacactt gaaccacgct cttttctggg aattgatgac tcccgagaaa
    27361 acagctcctt cagcagaact ggcagcagca atcgatgcaa catttggttc atttgaagaa
    27421 ttccaagcag ccttcactgc agcagcaaca actcgttttg gttcaggttg ggcatggttg
    27481 gttgtcaaca aagaagggaa acttgaagtg acttcaacag caaaccaaga cacaccaatc
    27541 tcagaaggta aaaaaccaat cttgggcttg gacgtttggg aacatgctta ctacgtgaaa
    27601 taccgcaacg tgcgtcctga ctacatcaaa gctttctttt cagtaatcaa ctggaataaa
    27661 gtagatgaat tgtacgcagc tgctaaataa tgatagttgg agggaagaat tgttcttctc
    27721 tttttaggtt ataagattct ggtctgacaa aatcgtcaga cttttttcat ttttatgaga
    27781 aacgtgctaa ctgctagaaa ttatggtaga ataaagtatt aagtaatcgt ggaaaaagga
    27841 tatctatgcg aaaagaaatt gcacctgaat tatacaacta taacaagttt cctggtccgg
    27901 agttccattt acacggggat aaggtcgaaa cggaagggat agctttttcc ttggttgaaa
    27961 atatcaagga tgcctttgat gtgacgactt ttaatcagcg tttttcagaa gtcttaacca
    28021 agtttgatta tatcgtgggg gactggagca acgaacagct tcgcctacga ggtttttaca
    28081 aggatgaccg aacagaagaa aaacttgaaa aaatcagtcg tttacaagac taccttttag
    28141 agtattgtag ttatggttgt gcctattttg tcttagaaaa tgaagcccct aagcgagcat
    28201 catttgacaa gaaaatgcgt aagacggaag aagaaacacc ttctagaaaa ggaaagaaac
    28261 cgactcaaac taaacgaaag tcgaatgcag ataagaaaaa tagacgtcgt cagaaagacc
    28321 agcattctca gaaagaggac aaggaacaac gtcattttgt cattcgtcag aagtgagtag
    28381 agaataagga gaagaaatga aaccctcaat tcatagtttg acacatcaaa ccatgcagga
    28441 atgggtattg gagcagggag aaaagaaatt ccgtgcagat caaatctggg aatggctcta
    28501 ccgtaaacgt gtgcagtcat ttgaagaaat gaccaacctt tccaaggatt tgattgctaa
    28561 gctcaatgac cagtttgtgg tcaatccctt gaaacaaggt attgtgcaag agtctgctga
    28621 tggtacagtc aaatatctct ttgaattgcc tgacggtatg ttaattgaga ctgtactcat
    28681 gtgtcaacac tatggtttat ctgtctgtgt gaccactcag gtcggctgta atatcggttg
    28741 taccttctgt gcctctggtt tgattaagaa gcagcgtgac ctcaataacg gtgaaatcgt
    28801 agcgcaaatc atgctggttc agaaatactt tgatgagcgt ggtcaggatg aacgcatcag
    28861 ccatatcgtt gtcatgggaa tcggtgagcc ctttgataat tacaacaatg tcttgaattt
    28921 ctttcgtact atcaatgatg ataaaggaat ggctatcggt gctcgtcaca tcacggtttc
    28981 aatctcaggt ttggctcata aaattcgtga ctttgctgat gaaggggttc aggtcaatct
    29041 tgccgtgtct cttcacgcac ccaacaatga acttcgttca agtatcatga agattaaccg
    29101 tgcctttccg attgaaaaac tctttgctgc tattgaatac tacattgaga caacaaaccg
    29161 tcgtgtaacc tttgaatata tcatgcttaa tgaagtcaac gacggtgtgg aacaagcctt
    29221 ggaattggct gaattgctca agaacatcaa gaaatcgtct tatgtaaact tgattcctta
    29281 taacccagtt agtgagcatg accaatatag ccgtagtccc aaagagcgcg tgttggcttt
    29341 ctatgatacg cttaagaaaa aagggggcaa ctgtgtggtt cgtcaagagc atggtacaga
    29401 tattgacgca gcttgtggac aattgctctt taacacaatg aaacgtgacc gccagaaggc
    29461 agtcgcagcg gtaaatcctt aatgatgaag aagacttata atcatatttt ggtctgggga
    29521 gtcattttct atagcatttg cattgtctat ttttgcttta ctcctcaaga acaatctacc
    29581 gtgggagtgg gaactccaga tattcagcat cttggacgcc tggtttttct tttgactcct
    29641 ttcaattctc tctggaaact gggcgaagtg agtgacattg gacaattatg ttggattttt
    29701 ttacaaaata tcctcaatgt cttcttgttt tttcctctga ttttccaact cctttatcta
    29761 tttccaaatt tgcggaaaac aaaaaaggtc cttcttttta gttttcttgt gagtcttgga
    29821 atcgagtgta cgcaattaat cttggacttt ttctttgatt tcaatcgcgt ctttgagatt
    29881 gatgatttgt ggaccaacac tttgggtggc tatctggctt ggctccttta taaacgatta
    29941 cataaaaaca agataaggaa ttaaaatgag tattttagaa gttaaaaatc tgagtcacgg
    30001 ttttggtgac cgtgcaattt ttgaagatgt gtccttccgt ctcctcaagg gggaacatat
    30061 cggcctggtc ggtgccaatg gtgaaggaaa atcaaccttt atgagtatcg tgactggtaa
    30121 aatgctgcca gatgaaggaa aggttgagtg gtccaaatat gtgacggctg gttacttgga
    30181 tcagcactct gtccttgctg aaagacagtc ggtgcgtgat gttctccgta cggcttttga
    30241 tgagcttttc aaagctgaag ctcgtatcaa tgacctctat atggaaatgg ctgaagacgg
    30301 tgcggatgtt gatgctctca tggaagaagt aggagaactt caagaccgtc tggagagtcg
    30361 tgatttctat accttggatg ctaagattga cgaagtagcg cgtgctcttg gtgttatgga
    30421 ctttggcatg gatacggatg taacttcttt gtcaggtggg caaagaacca aggtgctttt
    30481 ggcaaaactt ctccttgaaa agcctgatat cttgctgttg gacgagccga ccaactactt
    30541 ggatgctgag catattgatt ggctcaagcg ctatctccaa aactatgaga atgcctttgt
    30601 tctcatttcg cacgatattc cattcctcaa tgacgttatc aatattgtct atcatgtgga
    30661 aaatcaacag ctgacgcgtt actctggtga ctactaccag ttccaagaag tttatgctat
    30721 gaagaaatct cagctagagg cagcctacga acgccagcag aaagagattg cagacctcaa
    30781 ggactttgtg gctcgtaata aagcccgtgt tgcaactcgt aatatggcta tgtctcgtca
    30841 aaagaaattg gataagatgg atattatcga actccaaagt gagaaaccaa aaccatcctt
    30901 tgatttcaaa ccagctcgta caccagggcg ctttatcttc caaaccaaga acttgcaaat
    30961 tggttacgac cttcctctta ctaagccttt aaatcttacc ttcgaacgca atcaaaaggt
    31021 tgcgattatt ggtgctaatg gtattggaaa aacaactctc ttgaagagtc tcttgggcat
    31081 tatctcgcca atcgctgggg aagtggagcg tggagattat ttagaacttg gttattttga
    31141 gcaggaagta gaaggcggta atcgccaaac tcctcttgaa gctgtctgga atgcctttcc
    31201 tgcccttaat caagcagaag tccgtgcagc ccttgcccgt tgtggtttga caaccaaaca
    31261 tattgaaagc cagattcaag tattatcagg gggagagcaa gccaaggttc gtttctgtct
    31321 cttgatgaat cgtgaaaaca acgttttagt gctggacgag ccgaccaacc atttggatgt
    31381 ggatgcaaag gatgagctca aacgcgctct caaagaatat aggggatcta tccttatggt
    31441 ctgccacgag ccagactttt atgaaggctg gatagaccaa atatgggatt ttaataattt
    31501 aacttaagaa tgagagtaaa agaaatacag taccgaatgt ggatactgta tttttttggt
    31561 ttttaagatt taaaatcgta gtcttttacc acttcgatgc tgtcgattgt gatagcagta
    31621 gttggcttgt ctttttcatc tttttcggcc ttagcaatct tatccacaac atccataccg
    31681 tcaatcactt gaccaaagac tgggtgtttg ccatctagac tagggtttcc accttctttg
    31741 taggcttcga taattttctg tggatacttg cttgtaggga gtttagaaga ggtatctgta
    31801 gagctttggt tgatgaagaa ctggctgcca ttggtgtttg gttgaccagt attagccata
    31861 gcaagagcac cacggatgtt atacaaataa ggagtaatct cgttcttgaa accagttcct
    31921 ttgtctttag tcttatcctt gtcatgccag atggactgac cacctgtacc gtcccctttt
    31981 ggatctccag tttggaccat aaagccatcg atgacacggt ggaaggtaat accgttatag
    32041 tagccttctt tggcgtgagt gaggaaattt tcaaccgcta gaggagcgag tttagggaag
    32101 agtttaatgc gaatatcacc ttggcttgtg tggagaatca cttcggcttc atcttcagca
    32161 acttccttag atagttgtgg gaaattggcg ttttcgtttg ttaaagcatc gtttaactcc
    32221 ttggcagatt gggcagctac tttggaactt tcttcagcag caagactgga atcaacataa
    32281 tcatcaccac gcagactgcg ttggacgctg ctacacccag ctagggctac agtagacagt
    32341 aaaagaaggg ttgctagttt tttcattctg atcctctcaa aaattcattt ataccattgt
    32401 accctaaaaa gaagtggatt tcaaatatta gtagtttaca gaactggctt agataatagt
    32461 tgggatttca tcatcatctt gaaaatcttc aacttcttca acttcttccc cagtaaatgg
    32521 tttctgaaaa gaacttagta taaaacgggc aattggttca acaattagga aatttagagg
    32581 aagagctgca ataaagttta cgaaccaggc gcttagatag gtattgggtg tgatagcaat
    32641 gccattgtaa aaaagtccat agaaggacat gaaagtgacc agctaattct tcttctgaaa
    32701 aatgctcatg aagggcttga tccaggtcgc aagatttcat tttagaaagt ccagtaactc
    32761 ccttcttctt caggatattc tttttcatgg tattatttag atggtcaagt gagtcaaaag
    32821 aagtttcgac aagagcatac cctttttcta tcagagtttt tagatgttta ggggcatcaa
    32881 taccataagt gtactcaaag tattttggaa accagatctt aagaaagctc gtaaagctag
    32941 ccagttctct aaacgctaag aactagctac aacacagcat ttacaacact tcatggttca
    33001 caccatgggg tgctttttaa tgattttaag caaaattcac acttaattga aagttattta
    33061 aattagatga aaatttattt tttgaaaaag cgggaaaaca ttgattctaa gcgaattttg
    33121 aatcatattc gaatgggagt ttttaaaatc atgtttcagt ggtaaaagta ccaaactgga
    33181 ttctccatag taaaatgata tctcctgcta gtgaatcatc tactaataag tccatatttc
    33241 gcttgggaac gggcttggga cttagaagcc aagtatccaa ctctcgttca ggcgatatga
    33301 agggtttgac ttggtgttct ttataaaatt tttctaaaat agtattcacg gatagcatct
    33361 ttcaaacatt tatttcctat tctaacaaat ttctaaatac tttaagaaat ttatagtctg
    33421 tcaagttttt ttcttgacac atgccagaaa tctgctataa tagaacatgt gctaaatagc
    33481 tcagctattt caccgaaata aaaaattaaa gaaatgagac tttaaaaatg gcagttaaaa
    33541 tccgtttgac tcgtatgggt tctaagaaaa aacctttcta ccgtatcaac gtagcagatt
    33601 cacgttcacc acgtgacgga cgtttcatcg aaacagttgg aacttacaac ccacttgttg
    33661 ctgaaaacca agtaactttg aaagaagacc gcgttcttgc atggttggct aatggagctc
    33721 aaccttcaga cacagtacgt aacatccttt caaaagaagg cgtattgaaa aaattccacg
    33781 attctaaatt ctcaaaataa gtttaaagta ggttgacaga tggatacgat tgaaaatctc
    33841 attattgcga ttgtgaaacc cttaatttca caaccagatg ccttaactat caagattgag
    33901 gatacaccag aatttttgga atatcatttg aatcttgatc aaagcgatgt gggtcgtgta
    33961 atcggtcgta agggtcgcac tatttctgcg ataagaacga ttgtctactc tgtcccaact
    34021 gaatacaaaa aagtaagaat cgttattgac gaaaaataag aagggcggga cggatgtctc
    34081 gcttttttgt gtggaataga ag
//
LOCUS       DAVBOG010000022        33063 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.022, whole genome shotgun sequence.
ACCESSION   DAVBOG010000022 DAVBOG010000000
VERSION     DAVBOG010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 33063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 33063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..33063
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.022"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(339..1319)
                     /locus_tag="VQ865_001096"
     CDS             complement(339..1319)
                     /locus_tag="VQ865_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylxylan esterase"
                     /protein_id="HET3135442.1"
                     /translation="MKNPALLEEIKTYRGRDEVPEDFDAFWDGEVKNVSTLPSYHLEE
                     RDFHIPQVKCYELTFEGSKEGKVYARIVLPKSEEKVPLIFHFHGYMGRGWDWADMLGF
                     TVAGYGVVSMDVRGQSGYSQDGLRSPLGNTVKGHIIRGAMEGRDHLFYKDVYLDIYQL
                     VEIVASLSQVDEKRLSSYGASQGGALALVAAALNPRIQKTVAIYPFLSDFRRVIEIGN
                     TSEAYDELFRYFKFHDPFHETEEEIMATLAYIDVKNLAHRIQGEVKMITGLDDDVCYP
                     ITQFAIYNRLTCDKTYRIMPEYAHEAMNVFVDDQVYNWLCGSEIPFKYLK"
     gene            complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ865_001097"
     CDS             complement(1635..3650)
                     /gene="recG"
                     /locus_tag="VQ865_001097"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HET3135443.1"
                     /translation="MNLHQPLHVLPGVGPKSAEKYAKLGIENLQDLLLYFPFRYEDFK
                     TKQVLELEDGEKAVLSGQVVTPASVQYYGFKRNRLRFSLKQGEVVFAVNFFNQPYLAD
                     KIELGATLAVFGKWDRAKASLTGMKVLAQVEDDLQPVYRLAQGISQASLVKVIKTAFD
                     QGLDLLIEENLPQSLLDKYKLMSRCQAVRAMHFPKYLAEYKQALRRIKFEELFYFQMQ
                     LQMLKSENRVQGSGLVLNWSQEKVTAVKVSLPFALTQAQEKSLQEILTDMKSDHHMNR
                     LLQGDVGSGKTVVAGLAMFAAVTAGYQAALMVPTEILAEQHFESLQNLFPNLKLALLT
                     GSLKAAEKREVLETIAKGEADLIIGTHALIQDGVEYARLGLIIIDEQHRFGVGQRRIL
                     REKGDNPDVLMMTATPIPRTLAITAFGDMDVSIIDQMPAGRKPIVTRWIKHEQLPQVL
                     TWLEGEIQKGSQVYVISPLIEESEALDLKNAIALSEELTTHFAGKAEVALLHGRMKSD
                     EKDQIMQDFKERKTDILVSTTVIEVGVNVPNATVMIIMDADRFGLSQLHQLRGRVGRG
                     DKQSYAVLVANPKTDSGKDRMRIMTETTNGFVLAEEDLKMRGSGEIFGTRQSGLPEFQ
                     VADIIEDFPILEEARKVASYISSIEAWQEDPEWRMIALHLEKKEHLD"
     gene            complement(3669..4772)
                     /locus_tag="VQ865_001098"
     CDS             complement(3669..4772)
                     /locus_tag="VQ865_001098"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000648075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HET3135444.1"
                     /translation="MKASPHRPTKALIHLGAIRQNIQQMGAHIPQGTLKLAVVKANAY
                     GHGAVAVAKAIQDDVDGFCVSNIDEAIELRQAGLSKPILILGVSEIEAVALAKEYDFT
                     LTVAGLEWIQALLDKEVDLTGLTVHLKIDSGMGRIGFREASEVEQAQDLLQQHGVCVE
                     GIFTHFATADEESDDYFNAQLERFKTILASMKEVPELVHASNSATTLWHVETIFNAVR
                     MGDAMYGLNPSGAVLDLPYDLIPALTLESALVHVKTVPAGACMGYGATYQADSEQVIA
                     TVPIGYADGWTRDMQNFSVLVDGQACPIVGRVSMDQITIRLPKLYPLGTKVTLIGSNG
                     DKEITATQVATYRVTINYEVVCLLSDRIPREYY"
     gene            complement(4762..5130)
                     /locus_tag="VQ865_001099"
     CDS             complement(4762..5130)
                     /locus_tag="VQ865_001099"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HET3135445.1"
                     /translation="MRMIVGHGIDIEELASIESAVTRHEGFAKRVLTAQEMERFTSLK
                     GRRQIEYLAGRWSAKEAFSKAMGTGISKLGFQDLEVLNNERGAPYFSQAPFSGKIWLS
                     ISHTDQFVTASVILEENHES"
     gene            complement(5169..6200)
                     /locus_tag="VQ865_001100"
     CDS             complement(5169..6200)
                     /locus_tag="VQ865_001100"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3135446.1"
                     /translation="MAFIEKGQEIDMEVIKAETQLSAEALRLKESRDRELADIISGED
                     DRILLVIGPCSSDNEEAVLEYARRLSALQKKVADKIFMVMRVYTAKPRTNGDGYKGLV
                     HQPDTSKAPSLINGLQAVRQLHYRVITETGLTTADEMLYPSNLILVDDLVSYHAVGAR
                     SVEDQEHRFVASGIDAPVGMKNPTSGNLGVMFNAIYAAQNKQTFLYHGQEVETSGNPL
                     AHVILRGAVNEYGNYMPNYYYENLLQAIERYETMGLENPFILIDTNHDNSGKQYMEQI
                     RIVRQTLQNRDWNEKIKKTVRGFMIESYLADGRQNQPEIFGCSITDPCLGWENTEALV
                     EEIYVTLTK"
     gene            complement(6202..7233)
                     /locus_tag="VQ865_001101"
     CDS             complement(6202..7233)
                     /locus_tag="VQ865_001101"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000232189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HET3135447.1"
                     /translation="MVFTAKSSKINIEEVRALSKLEGQALERKSQRDQELEAIIRGED
                     QRILLVIGPCSSDNEEAVLEYAKRLAVLQEEVADRIFMVMRVYTAKPRTNGDGYKGLI
                     HQPNATEAPSLINGIKAVRHLHYRVITETGMTTADEMLYPENLPLVDDLISYMAVGAR
                     SVEDQQHRFVASGAGFSTGFKNPTSGNLNVMFNGIYAAQNKQSFLFLGKEVETTGNPL
                     SHAILRGALNEYGKNIPNYYYDNLIDTIAQYEKMGLENPFIIIDTNHDNSGKQYIEQI
                     RIVRQTLINRAWNEKIKQFVRGFMIESYLEDGRQNEPEVFGKSITDPCLGWDNTEALV
                     REIYKTLGE"
     gene            complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ865_001102"
     CDS             complement(7314..9827)
                     /gene="secA"
                     /locus_tag="VQ865_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HET3135448.1"
                     /translation="MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAK
                     TVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLFPYKVQVMGGIVLHHGDVPEMRT
                     GEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLATKS
                     PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEAR
                     TPLIVSGANAVETSQLYHMADHYVKSLNKDDYIIDVQSKTIGLSDSGIDRAESYFKLE
                     NLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQFTGRTMEGRRYSDGL
                     HQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIP
                     IPTNRPVQRIDHSDLLYASIESKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKL
                     VAAGVPHEVLNAKNHYREAQIIMNAGQRGAVTIATNMAGRGTDIKLGEGVRELGGLCV
                     IGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFERLNMSE
                     EAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYTQRYDVITADRDL
                     APEIQSMIKRTLERVVDGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAI
                     KEELFQRALKVYDSQVSKLRDEEAVKEFQKVLILRVVDNKWTDHIDALDQLRNAVGLR
                     GYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAERHISTTATRN
                     IAAHQASMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ"
     gene            complement(9973..10263)
                     /locus_tag="VQ865_001103"
     CDS             complement(9973..10263)
                     /locus_tag="VQ865_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000940707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135449.1"
                     /translation="MAHLKSFITRYSKVYIGLVLLIWIAFFFLPWGSPILGGGKIDLF
                     SIQKVLLVFGILSILMALLSKKVSLFVFGLICCLSLWINLFILFAILPILGN"
     gene            complement(10291..10923)
                     /locus_tag="VQ865_001104"
     CDS             complement(10291..10923)
                     /locus_tag="VQ865_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001235275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3135450.1"
                     /translation="MRLEIINGQKIYGKRPILNQLNLVFQSGKIYGLKGDNGSGKTVL
                     LKILAGYIKLDKGKVLQDGKVYGIKNHYIQDAGILIEKVEFLSHLSLRENLELLRYFS
                     SKVTEKRIAYWIQYYDLQEFEDVEYRHLSLGTKQKMALIQAFISSPSILFLDEPMNAL
                     DEKSVRLTKQVILSYLKKENGLVILTSHISEDISDLCTDVLVVENGHIQM"
     gene            complement(10927..11568)
                     /locus_tag="VQ865_001105"
     CDS             complement(10927..11568)
                     /locus_tag="VQ865_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135451.1"
                     /translation="MFKNFNNIWLKRKIVLLLRIVLMMILINYLLSTAVQKQDAVIFF
                     KRELISIFSYNDYSEANLEIPKLLLNLSLFMVGWLSVILLESDLADHYHHLIRYQSSS
                     FFDYTRKRLVVISKFFTQDLFVWFLGLLPLGIHFKTVALFFLLAQLMMLYLLLSYLIA
                     LISAGAGFSFFLYFLAFVGQEWMMDHIVTVYLVLLSLLVMLILSRLEEKFKKG"
     gene            complement(11561..12352)
                     /locus_tag="VQ865_001106"
     CDS             complement(11561..12352)
                     /locus_tag="VQ865_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135452.1"
                     /translation="MKIPLLTLARHKFVYVLLTLLFLALVYRDVLMTYFFFDIHAPDL
                     AKFDGQAIKNDLLKSALDFRILQFNLGFYQSFIIPIIIVLLGFQYIELKNKVLRLSIG
                     REVSYQGLKRKLTLQVASIPCLIYLVTVLIIAIITYFFGTFSPLEWNSLFSDGSGLQR
                     LLDGEIKSYLFFTCVLLIGIFINAIYFLQIVDYVGNVTRSAITYLMFLWLGSMLLYSA
                     LPYYMVPMTSLMQASYGDVSLMKLFTPYILYVVPYMVLKKYEDNV"
     gene            complement(12537..12872)
                     /locus_tag="VQ865_001107"
     CDS             complement(12537..12872)
                     /locus_tag="VQ865_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135453.1"
                     /translation="MEYLFKMIILLPCFYFFSWIEKANRDSKIFPIFYYFYWIYITLY
                     ALFSLAWTVFSVLFFNIVLRNLTDIKLWGIWLLLLLIAFASDWLDYICFKKMLDLRRE
                     LGKSKGGRH"
     gene            complement(13012..13347)
                     /locus_tag="VQ865_001108"
     CDS             complement(13012..13347)
                     /locus_tag="VQ865_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000400494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135454.1"
                     /translation="MEHLFKFLLLAPYFYFDNWIEKANRNSKFFPIFYYFYWFYIPFY
                     SLFSLAWTVVSVLFFNTVLRNVTDIKLWGIWFLFILLAIGMNWLTYSCFKEMFRLRQE
                     LGKSKGGRH"
     gene            complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ865_001109"
     CDS             complement(13438..14748)
                     /gene="der"
                     /locus_tag="VQ865_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018377046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HET3135455.1"
                     /translation="MALPTIAIVGRPNVGKSTLFNRIAGERISIVEDVEGVTRDRIYA
                     TGEWLNRSFSMIDTGGIDDVDAPFMEQIKHQAEIAMEEADVIVFVVSGKEGITDADEY
                     VARKLYKTHKPVILAVNKVDNPEMRNDIYDFYALGLGEPLPISSVHGIGTGDVLDAIV
                     ENLPNEYEEENPDVIKFSLIGRPNVGKSSLINAILGEDRVIASPVAGTTRDAIDTHFT
                     DTDGQEFTMIDTAGMRKSGKVYENTEKYSVMRAMRAIDRSDVVLMVINAEEGIREYDK
                     RIAGFAHEAGKGMIIVVNKWDTLEKDNHTMKNWEEDIREQFQYLPYAPIIFVSALTKQ
                     RLHKLPEMIKQISESQNTRIPSAVLNDVIMDAIAINPTPTDKGKRLKIFYATQVATKP
                     PTFVIFVNEEELMHFSYLRFLENQIRKAFVFEGTPIHLIARKRK"
     gene            complement(14762..15476)
                     /locus_tag="VQ865_001110"
                     /pseudo
     CDS             complement(14762..15476)
                     /locus_tag="VQ865_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140867.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent oxidoreductase"
     gene            complement(15473..16369)
                     /gene="dnaI"
                     /locus_tag="VQ865_001111"
     CDS             complement(15473..16369)
                     /gene="dnaI"
                     /locus_tag="VQ865_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HET3135456.1"
                     /translation="MESVGDVLKRQPSRFYYQDLVQKIMKDPDVAAFIQQESLTPEEL
                     NRSISKFNQYITERDKFLRGDTDYIAKGYKPILVKNHGYADVSYEETPELIAAEKEAA
                     IKNRLKLINLPASLKKASLAQVDLDDLGRLPVFEKLLAFVEQYPAIRKGLYLYGDFGV
                     GKSFMVAALAHDLSEKRGVSSTLLHYPSFVIDVKNAISDGNVKTLVDEIKLSEVLILD
                     DIGAEQSTVWVRDEILQVILQYRMQENLPTFFTSNFNFEDLEKHFAKVKHGNDETWEA
                     RRVMERIRYLAEETRLEGVNRR"
     gene            complement(16370..17539)
                     /locus_tag="VQ865_001112"
     CDS             complement(16370..17539)
                     /locus_tag="VQ865_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation and membrane attachment
                     family protein"
                     /protein_id="HET3135457.1"
                     /translation="MKPIDRFSYLKNNRVSQDTSSLVQCYLPIIGQEALSLYLYTISF
                     WDNGRKEYLFSSILNHLNFGMDRLIKSLKILSAFNLLTLYQKGDVYQLALHAPLSSQD
                     FLEHPVYRRLLEKKIGDSAVEDLKVESADGEEIPVSLNQVFPELAELGSQEDLGLKKK
                     VANDFDLEHFRQLMARDGLRFADEQSDVLNLFAIAEEKKWTWFETYQLAKSTAVSQVI
                     STKRMREKIAQKPVSSDFSLKETTIIKEAKSKTALQFLAEIKQTRKGTITQTERELLQ
                     QMAGLGLLDEVINIILLLTFNKVDSANINEKYAMKVANDYAYQKIHSAEKAVLRIRER
                     GQKAKTQKQNQTAPVKTNVPKWSNPEYKNETSEETRLELERKKQELLARLEKGGD"
     gene            complement(17540..18013)
                     /gene="nrdR"
                     /locus_tag="VQ865_001113"
     CDS             complement(17540..18013)
                     /gene="nrdR"
                     /locus_tag="VQ865_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001203675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HET3135458.1"
                     /translation="MRCPKCGATKSSVIDSRQAEEGNTIRRRRECDECQHRFTTYERV
                     EERTLVVVKKDGTREQFSRDKIFNGIIRSAQKRPVSSDEINMVVNRIEQKLRGRNENE
                     IQSEDIGSLVMEELAELDEITYVRFASVYRSFKDVSELESLLQQITQSSKKKKER"
     gene            18153..18518
                     /locus_tag="VQ865_001114"
     CDS             18153..18518
                     /locus_tag="VQ865_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3135459.1"
                     /translation="MSWTFDNKKPIYLQIMEKIKLQIVSHTLEPNQQLPTVRELASEA
                     GVNPNTIQRALSDLEREGFVYSKRTTGRFVTKDKELIAQSRKQLSEEELEHFVSSMTH
                     FGYEKEELPGVVSDYIKGV"
     gene            18523..19218
                     /locus_tag="VQ865_001115"
     CDS             18523..19218
                     /locus_tag="VQ865_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135460.1"
                     /translation="MSLLVFENVSKSYGATPALENVSLDIPAGKIVGLLGPNGSGKTT
                     LIKLINGLLQPDQGRVLINDMDPSPATKAVVAYLPDTTYLNEQMKVKEALTYFKTFYK
                     DFNLERAHHLLADLGIDENSRLKKLSKGNKEKVQLILVMSRDARLYVLDEPIGGVDPA
                     ARAYILNTIINNYSPTSTVLISTHLISDIEPILDEIVFLKDGKVVRQGNVDDIRYESG
                     ESIDQLFRQEFKA"
     gene            19235..20002
                     /locus_tag="VQ865_001116"
     CDS             19235..20002
                     /locus_tag="VQ865_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000498762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135461.1"
                     /translation="MFWNLVRYEFKNVNKWYLALYAAVLVLSALIGIQTQGFKNLPYQ
                     ESQATMLLFLATVFGGLMLTLGISTIFLIIKRFKGSVYDRQGYLTLTLPVSEHHIITA
                     KLIGAFIWSLISTAVLALSAVIILALTAPEWIPLSYVITFVETHLPQIFLTGISFLLN
                     TISGILCIYLAISIGQLFNEYRTALAVAVYIGIQIVIGFIELFFNLSSNFYVNSLVGL
                     NDHFYMGAGIAIVEELIFIAIFYLGTYYILRNKVNLL"
     gene            complement(20355..20615)
                     /locus_tag="VQ865_001117"
     CDS             complement(20355..20615)
                     /locus_tag="VQ865_001117"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135462.1"
                     /translation="MTALGAAGDNLLLKIGSYIPFISTFFMPFRTINGYAEGAEAWIS
                     LAITVIFAVVATGFIGRMYASLVLQTDDLGIWKTFKRALSYK"
     gene            complement(20616..21554)
                     /locus_tag="VQ865_001118"
     CDS             complement(20616..21554)
                     /locus_tag="VQ865_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001854926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135463.1"
                     /translation="MRNMWVVIKETYLRHVESWSFFFMVISPFLFLGISVGIGHLQGS
                     SMAKNNKVAVVTTVPSVAEGLKNVNGVNFDYKDEASAKEAIKEEKLKGYLTIDQEDSV
                     LKAVYHGETSLENGIKFEVTGTLNELQNQLNRSTASLSQEQEKRLAQTIQFTEKIDEA
                     KENKKFIQTIAAGALGFFLYMILITYAGVTAQEVASEKGTKIMEVVFSSIRASHYFYA
                     RMMALFLVILTHIGIYVVGGLAAVLLFKDLPFLAQSGILDHLGDAISLNTLLFILISL
                     FMYVVLAAFLGSMVSRPEDSGKALSPLMILIMGGFF"
     gene            complement(21551..22444)
                     /locus_tag="VQ865_001119"
     CDS             complement(21551..22444)
                     /locus_tag="VQ865_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135464.1"
                     /translation="MLEVRSLEKSFGSKQVLFGIDFQARPGRILGLVGKNGAGKTTIF
                     HSILKFLEYQGEIGLDGQDIRQEIYARIGYLPEERSLMPKLTVLEQVRYLATLKGMDA
                     KEVKEKLPQWMKRLEVKGKLTDKIKSLSKGNQQKIQLIITLIHEPDLIILDEPFSGLD
                     PVNTELLKQVIFQEKERGATIIFSDHVMTNVEELCDDILMIRDGRVVLHGPVQDVRNQ
                     YGKTRLFVSSERSKEELENLPHVKQVSLTKQGSWKLILEDESAGRELFPILTQGQYIA
                     TFDQQAPTIDEIFKLESGVEV"
     gene            22567..22758
                     /locus_tag="VQ865_001120"
     CDS             22567..22758
                     /locus_tag="VQ865_001120"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135465.1"
                     /translation="MKIKEQTRKPAVDCSKYSFEVADKTDEVSSKHCFEVVDRTDEVS
                     NYIYGKAKLTWFEEIFEEY"
     gene            23151..23339
                     /locus_tag="VQ865_001121"
                     /pseudo
     CDS             23151..23339
                     /locus_tag="VQ865_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            23754..24371
                     /locus_tag="VQ865_001122"
     CDS             23754..24371
                     /locus_tag="VQ865_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HET3135466.1"
                     /translation="MSQDKQMKAVSPLLQRVINISSIVGGVGSLIFCIWAYQAGILQS
                     KETLSAFIQQAGIWGPPLFIFLQILQTVVPIIPGALTSVAGVFIYGHIIGTIYNYIGI
                     VIGCAIIFYLVRLYGAAFVQSVVSKRTYDKYIGWLDKGNRFDRFFIFMMIWPISPADF
                     LCMLAALTKMSFKRYMTIIILTKPFTLVVYTYGLTYIIDFFWQML"
     gene            complement(24414..25301)
                     /locus_tag="VQ865_001123"
     CDS             complement(24414..25301)
                     /locus_tag="VQ865_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HET3135467.1"
                     /translation="MTKLYGSLEAGGTKFVCAVGDENFNVVEKTQFPTTTPIETIDKT
                     IEFFSKFDNLAGLAVGSFGPIDIDKNSKTYGFITTTPKPNWANVDLLGALRRALNVPM
                     YFTTDVNSSAYGEVVARNNAGGRIENLVYYTIGTGIGAGVIQRGEFIGGVGHPEMGHY
                     YVARHPMDIEKEFKGVCPFHKGCLEGYAAGPSLEARTGVRGETIELNNPVWDVQAYYI
                     AQAAVNATVTFRPDVIVFGGGVMAQQHMLDRVREKFTSLLNGYLPVPDVRDYIVTPAV
                     AGNGSATLGNFVLAKEVSK"
     gene            complement(25450..27333)
                     /locus_tag="VQ865_001124"
     CDS             complement(25450..27333)
                     /locus_tag="VQ865_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3135468.1"
                     /translation="MNNQEIAKKVIDALGGRENVNSVAHCATRLRVMVKDEEKINKEV
                     IENLEKVQGAFFNSGQYQIIFGTGTVNKMYDEVVVLGLPTSSKDDMKAEVAKQGNWFQ
                     RAIRTFGDVFVPIIPVIVATGLFMGVRGLFNALEMPLPGDFATYTQILTDTAFIILPG
                     LVVWSTFRVFGGNPAVGIVLGMMLVSGSLPNAWAVAQGGEVTAMNFFGFIPVVGLQGS
                     VLPAFIIGVVGAKFEKAVRKVVPDVIDLLVTPFVTLLVMSILGLFVIGPVFHVVENYI
                     LIATKAILSMPFGLGGFLIGGVHQLIVVSGVHHIFNLLEVQLLAADHANPFNAIITAA
                     MTAQGAATVAVGVKTKNPKLKTLAFPAALSAFLGITEPAIFGVNLRFRKPFFLSLIAG
                     AIGGGLASILGLAGTGNGITIIPGTMLYVGNGQLPQYLLMVAVSFALGFALTYMFGYE
                     DEVDATAAAKQAEVAEEKEEVAPAALQNETLVTPIVGDVVALADVNDPVFSSGAMGQG
                     IAVKPSQGVVYAPADAEVSIAFPTGHAFGLKTRNGAEVLIHVGIDTVSMNGDGFEAKV
                     AQGDKVKVGDVLGTFDSNKIATAGLDDTTMVIVTNTADYASVAPVATGSVAKGDAVIE
                     VKI"
     gene            27709..29163
                     /locus_tag="VQ865_001125"
     CDS             27709..29163
                     /locus_tag="VQ865_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3135469.1"
                     /translation="MEWTTERRYRLYQDWTQEEIQHIKENMAQSPWHTHYHVEPKTGL
                     LNDPNGFSYFDGKWILFYQNFPFGAAHGLKSWAQLESDDLVHFKETGIKVLPDTPLDS
                     HGAYSGSAMQFGDNLFLFYTGNVRDENWIRHPYQIGALMDKEGKITKIDKILIDQPAD
                     STDHFRDPQIFNFKGQYYAVVGGQDLEKKGFVRLYKAVNNDYTNWQAVGDLDFANDRT
                     AYMMECPNLIFVEEQPVLLYCPQGLDKKVLDYDNIFPNMYKIGASFDPKNAKMVDVSQ
                     LQNMDYGFEAYATQAFNAPDGRALAVSWLGLPDVSYPSDCFDHQGTFSLVKELTIKDD
                     KLYQYPVAAIKDLRASEEAFSNRSQTKNTYELELNLEANSQSEIVLLADKEGKGLSIN
                     FDLVNGQVTVDRSQAGEQYAQEFGTTRSCPIENQATTATIFIDNSVFEIFINKGEKVF
                     SGRVFPHADQNGILIKSGNPTGTYYELDYGRKTN"
     gene            29144..30109
                     /locus_tag="VQ865_001126"
     CDS             29144..30109
                     /locus_tag="VQ865_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002929307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3135470.1"
                     /translation="MVAKLTDVAKLAGVSPTTVSRVINKKGYLSEKTIQKVNEAMREL
                     SYKPNNLARSLQGKSAKLIGLIFPNISNVFYAELIDKLEHQLFKNGYKTIICNSEHDS
                     EKEREYIEMLEANQVDGIISGSHNLGIEDYNRVTAPIISFDRNLSPDIPVVSSDNYAG
                     GVLAAQTLVKTGAQSIIMITGNDNSNSPTGLRHAGFASVLPKAPIINVSSDFSPVRKE
                     MEIKNILTREKPDAIFASDDLTAILIIKIAQELGISVPKELKVIGYDGTYFIENYYPQ
                     LATIKQPLEEIACLTIDLLLQKIEGKEVATTGYFLPVTLLPGKSI"
     gene            complement(30144..31418)
                     /locus_tag="VQ865_001127"
     CDS             complement(30144..31418)
                     /locus_tag="VQ865_001127"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000704367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HET3135471.1"
                     /translation="MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTV
                     ADQLSENVVGTFSLPYSLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFT
                     AQVHQRQMIGQVALYQVANPKLAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVE
                     QIKGEPDFLVVYIHVDTQEAMGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSL
                     VTASCRIAFRYLSRQKDQGREIAEKIALASQFAQADPYRAATHNKGIFNGIDAILIAT
                     GNDWRAIEAGAHAFASRDGRYQGLSCWTLDLEREELVGEMTLPMPVATKGGSIGLNPR
                     VALSHDLLGNPSARELAQIIVSIGLAQNFAALKALVSTGIQQGHMKLQAKSLALLAGA
                     SESEVAPLVERLISDKTFNLETAQRYLENLRS"
     gene            complement(31418..32590)
                     /locus_tag="VQ865_001128"
     CDS             complement(31418..32590)
                     /locus_tag="VQ865_001128"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004181031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HET3135472.1"
                     /translation="MTIGIDKIGFATSQYVLKLQDLAEARGIDPEKLSKGLLLKELSI
                     APLTEDIVTLAASASDSILTEQERQEVDMVIVATESGIDQSKAAAVFVHGLLGIQPFA
                     RSFEIKEACYGATAALHYAKLHVENSPESKVLVIASDIAKYGIETPGEPTQGAGSVAM
                     LITQNPRMMAFNNDNVAQTRDIMDFWRPNYSTTPYVNGVYSTQQYLDSLKTTWLEYQK
                     RYQLTLDDFAAVCFHLPYPKLALKGLKKIMDKSLPQEKKDLLQKHFDQSILYSQKVGN
                     IYTGSLFLGLLSLLENTDSLKAGDKIALYSYGSGAVAEFFSGELVEGYEAYLDKDRLN
                     KLNQRTVLSVADYEKVFFEEVNLDETNSAQFAGYENQDFALVEILDHQRRYSKVEK"
     gene            complement(32721..32969)
                     /locus_tag="VQ865_001129"
     CDS             complement(32721..32969)
                     /locus_tag="VQ865_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135473.1"
                     /translation="MVSSSGSEFQSGWQEHQLIAEKVSKTLDKTFDKDVREIPTSQFY
                     QKFVDEMGRTYSGNLILQELITVNGAYKATYIGELSSN"
BASE COUNT         9693 a         7423 c         6238 g         9709 t
ORIGIN      
        1 tttttgaaaa gtattaacac ctacagacaa gcctgacgat agcaagaact accctactcg
       61 ataggtatcg gcttttgctt tctgaaaaaa attattttaa gcaatttgac aaatctagca
      121 acaaaaaatt ttataaatac aatagattga aactagaata gtacaccttt gcttctaaaa
      181 cattgttaga aatcgatttg actgtcctga tcgatttgtc ctgtttttat ttcattttac
      241 tatatttcca tgataaaacg catagtatca agttttctta atcccctgat actatgcgta
      301 tttgtaattt ttaagatttt gtgcttagag tcgactcctt attttagata tttaaaagga
      361 atctcactcc cacagagcca gttgtagact tggtcatcga caaatacatt catggcttcg
      421 tgagcatact caggcatgat gcgataggtt ttatcgcagg tcagacgatt ataaatcgca
      481 aactgggtaa tgggatagca aacatcgtcg tccaagcccg taatcatctt aacctcacct
      541 tggatacgat gggcaagatt tttgacatcg atataggcaa gggtcgccat gatttcctcc
      601 tctgtttcat ggaaggggtc gtgaaacttg aaataacgga aaagttcgtc gtaagcctcg
      661 ctagtattac caatctcaat cacccgtctg aagtctgaca agaagggata aatggcaact
      721 gttttctgaa ttcgaggatt gagcgctgct gcaactagag ctagagcccc tccttgtgag
      781 gcaccatagc tagaaagacg cttctcatca acctgagaca gactagcaac aatttcgacc
      841 aactggtaaa tatccagata aacatcctta taaaagaggt ggtcccgacc ttccatagca
      901 ccacggataa tatgcccctt cacggtattt cctaaaggag aacgcaagcc gtcttgtgag
      961 taacctgact ggccccgcac atccatggaa acaacaccgt aaccagctac ggtgaagccc
     1021 agcatgtcgg cccagtccca gccacgtccc atataaccat gaaaatggaa gattagtgga
     1081 accttctcct cactctttgg aagaacaatg cgtgcataga cctttccttc cttgcttcct
     1141 tcaaatgtta actcatagca cttgacttga ggaatgtgga aatctctttc ctccaagtgg
     1201 taggatggaa gcgtggaaac atttttcact tccccatccc agaaagcatc aaagtcttcc
     1261 ggaacctcat cccttcctct ataggtctta atttcttcta gcaaagctgg atttttcata
     1321 gcatgctcct tttattttgt aatcgttacc acaactgtag catatctatg taatcaatgc
     1381 aagaaagaag gataaataga aagtgaattt agattcttta cttttaggat gataggctga
     1441 aagtagtttt agaaacgaaa aagagcattt cgctctctct tctgtttata ctagtttttt
     1501 gcttccttct tttggaaagt ggtttggtaa tttactttaa tcgttactgt catatgagag
     1561 tcctcgtttc tttttgatga ctttagtata agagccaaac ctaaaaacta gcttaagttt
     1621 tccttagaga aagcttaatc cagatgttct ttcttttcca gatgaagggc aatcatgcgc
     1681 cactctggat cttcttgcca agcttctata gaactaatgt agctagcaac ctttcttgct
     1741 tcttctaaaa tcggaaaatc ttcgataata tcagccactt ggaactctgg aagtcctgac
     1801 tgtctggttc caaaaatctc accagaacca cgcattttca aatcttcctc cgcaaggaca
     1861 aatccattgg tcgtttctgt catgatacgc atgcggtctt tcccagaatc cgtcttggga
     1921 ttagcaacga gaacagcgta ggactgcttg tccccccgac cgacacgacc tctaagctgg
     1981 tgaagttgac tgagaccgaa gcgatcggca tccatgataa tcatgacagt cgcattggga
     2041 acgttgaccc caacctcaat aaccgtcgtc gaaaccagaa tatccgtctt tctctccttg
     2101 aaatcctgca tgatctggtc tttttcgtca ctcttcatcc taccatgtag aagagccacc
     2161 tctgccttgc ctgcaaaatg agtcgtcaac tcctctgata aggcaatggc atttttcaaa
     2221 tctagagctt ctgattcttc aatcaaagga gagatgacat agacttggga acctttttga
     2281 atttccccct ctaaccaagt caagacctga ggtagttgct catgtttgat ccagcgcgtc
     2341 acaataggct tccgacctgc tggcatctgg tcgataatgg aaacatccat atctccaaag
     2401 gctgtgatgg caagcgtccg tggaatggga gtcgccgtca tcatgaggac atctggattg
     2461 tcaccttttt cccgtaaaat acgcctttgc cctacaccaa aacggtgctg ctcatcgata
     2521 ataatcaaac caagacgagc atactccacc ccatcttgta tcagagcgtg agttcctata
     2581 atcaaatcag cctcaccctt ggcaatggtc tccaagactt ctctcttttc tgcagctttc
     2641 aaggaacctg tcaagagagc cagtttcaaa ttgggaaaaa ggttctgtaa actctcaaag
     2701 tgttgctctg cgaggatttc tgttggtacc attagggcag cctgataacc tgctgtcact
     2761 gccgcaaaca tggccaagcc agcgactacc gtttttccac tccccacatc cccttgtagg
     2821 agacgattca tgtggtggtc ggacttcata tcagttaaaa tttcctgcaa actcttttcc
     2881 tgagcttggg tcagggcaaa aggaagactt actttaactg ctgtcacttt ttcctgagac
     2941 caattcagaa ccagaccact tccctgaact ctattttcag acttgagcat ctgcagctgc
     3001 atttggaaat aaaagagttc ctcaaacttt atacggcgaa gagcctgctt gtattctgcc
     3061 aaatactttg gaaaatgcat agcacggact gcctgacaac gggacatgag tttgtatttg
     3121 tctagtaaag actggggcag attttcttct atcaagaggt ccagtccctg atcaaaagcc
     3181 gtcttgatga ccttgaccag actggcctgg ctgattccct gagccagacg atagacaggc
     3241 tggaggtcat cttctacctg agccagaacc ttcatcccag tcagactagc cttagcgcgg
     3301 tcccattttc caaagacagc aagggttgct cccaactcta ttttatcagc cagatagggc
     3361 tggttaaaga aattcaccgc aaaaacgacc tctccctgct tgagactaaa acgcaggcga
     3421 ttgcgcttga aaccataata ctggacacta gcaggagtca ctacctgacc agaaagaact
     3481 gccttctcac cgtcttccag ctccagcacc tgcttggttt tgaagtcttc ataacggaaa
     3541 ggaaagtaga gcaagagatc ttgcaagttt tcaattccta gtttggcgta tttttctgct
     3601 gactttggtc ccacaccagg caagacatgc aagggttgat gtagattcat gctccactcc
     3661 tttcttttct aataatattc tctcggaata cggtcgctga ggaggcaaac cacctcatag
     3721 ttaatggtta cgcggtaggt cgctacctga gttgcagtga tttccttatc cccattggag
     3781 ccaatcaagg ttaccttggt tcctagcgga taaagcttag gcaatcgaat agtgatttgg
     3841 tccatcgaaa ccctgccgac aattgggcaa gcttggccat ctaccaagac agagaaattt
     3901 tgcatgtctc ttgtccatcc atctgcatac ccgattggca cggtcgcgat gacttgctcg
     3961 ctatccgctt gataagttgc tccatagccc atgcaagctc cagctggaac tgtcttgaca
     4021 tgaaccagag cagactccaa ggtcaaggcc ggtatcaaat cataaggcaa atccaagacc
     4081 gctccacttg gattgaggcc atacatggca tctcccatac gaaccgcatt gaaaatagtc
     4141 tctacatgcc aaagagtcgt tgcagaattg ctagcatgaa ccagctctgg aacttccttc
     4201 atactagcta aaatagtttt aaaccgttct aactgggcat taaaatagtc atctgattcc
     4261 tcatcagcag tagcaaagtg ggtaaagatt ccttcaacac aaacaccgtg ttgttggagc
     4321 aaatcttgag cctgctcaac ctcacttgcc tctctaaaac caatccgtcc catccctgaa
     4381 tcaatcttga ggtggactgt caatccagtt aggtccactt ccttatctaa gagtgcttga
     4441 atccactcca gtccagccac tgtcaaggtg aagtcatatt ctttagctag agcaacagct
     4501 tcgatttcag aaactcctaa aatgaggatt ggcttgctga gtccagcttg tctgagttca
     4561 atggcttcat cgatattgga aacgcaaaag ccatcaacat catcttgaat tgccttggca
     4621 acggcaacag ctccatgacc ataagcattg gccttaacca cagccaactt gagcgttcct
     4681 tgagggatat gagcccccat ttgctgaata ttttgtcgaa tagctcccag atgaatcaga
     4741 gccttggttg gtctatgtgg actagctttc atgattttcc tccaaaatga cactggctgt
     4801 cacaaactga tcggtgtggc tgatagacag ccaaatcttt cctgaaaatg gtgcctgact
     4861 aaaataaggc gccccacgtt cattgttcaa gacttccaaa tcctgaaaac cgagcttgct
     4921 aatgcccgtt cccatagcct tggaaaaggc ctccttagcc gaccagcgac cagctaaata
     4981 ttctatttgc ctgcgtcctt tgagactggt gaagcgctcc atttcctgag cggtcagtac
     5041 acgcttagca aatccttcat gtcgtgtaac tgcgctttct atcgaagcca attcttcaat
     5101 gtcaattccg tgtccaacta tcattctcat caaaaggagt tgagattccc caactccatc
     5161 cttttcactt attttgtcaa ggtaacataa atctcttcta ccaaggcctc tgtattttcc
     5221 caacctaggc aagggtcagt aatagagcaa ccaaagatct ctggttggtt ttgacgacca
     5281 tctgctaggt aagattcaat cataaatcct cgaaccgtct ttttaatttt ctcattccaa
     5341 tcacgattct gcaaggtctg gcgaacaatt cgaatctgct ccatatattg cttgcctgag
     5401 ttatcatggt tggtgtcaat gaggataaaa ggattttcaa gtcccatggt ttcatagcgt
     5461 tcaatggctt ggagtagatt ttcatagtag taattcggca tataattgcc atactcgttg
     5521 actgctccac ggaggataac atgggccaaa ggattacctg atgtctcaac ttcctgccca
     5581 tgataaagga aggtttgctt gttttgagca gcatagatgg cgttaaacat aacacccaaa
     5641 tttcctgagg ttggattttt catccctact ggtgcatcaa tcccagaagc cacaaagcgg
     5701 tgctcttggt cttccacaga acgagctcca acggcatggt agctgaccaa gtcatccacc
     5761 aagatcagat ttgacggata aagcatctca tctgccgttg tcaaaccagt ctctgtaatc
     5821 acgcggtagt gcaactggcg cacagcctgc aagccattaa tcaggcttgg agccttagaa
     5881 gtatctggct ggtgaactaa tcctttatag ccgtctccat tggtacgagg cttagcagta
     5941 tacacgcgca tgaccatgaa aatcttatcc gctaccttct tttgcaaggc agataaacgg
     6001 cgagcatatt ccaagaccgc ctcttcatta tcagaagagc aaggaccaat caccaagaga
     6061 atacggtcat cttcccctga aataatatct gccaattccc tgtcacggct ttccttgagt
     6121 ctcaaggctt ccgcagacaa ttgggtttca gccttgatga cttccatatc gatttcttga
     6181 cctttttcaa taaatgccat cttattctcc taacgttttg taaatttctc tgacaagagc
     6241 ttctgtgtta tcccaaccca ggcaagggtc tgtgatagac ttaccaaata cttctggctc
     6301 attttgtcga ccatcttcca gataagactc aatcataaaa ccacgaacga actgcttaat
     6361 tttttcattc caagcacggt taatcaaggt ctggcggaca attcggatct gttcaatata
     6421 ctgcttacca gaattgtcat gattggtatc aatgatgata aaaggatttt ccaagcccat
     6481 tttctcatac tgggcaatgg tatcaattaa attgtcataa tagtagttgg gaatattttt
     6541 tccatactca ttaagagcac cacgaagaat agcgtgtgaa agcgggttcc cagttgtttc
     6601 tacttctttt cctaagaaaa ggaaactttg tttgttttga gcagcataaa tcccattaaa
     6661 catgacattg agatttccag aggttggatt tttaaaacca gtagaaaatc ctgccccact
     6721 tgccacaaag cggtgttgct ggtcttcaac tgaacgggca ccaactgcca tgtaagaaat
     6781 caaatcatct acaagcggaa ggttttcagg ataaagcatt tcatcagcag ttgtcatccc
     6841 tgtttctgtg atgacacgat agtgaagatg gcgaacggct ttgattccat tgataagact
     6901 aggcgcttct gtcgcgttag gctggtgaat caagccctta tagccatctc cgttggtacg
     6961 gggtttggca gtataaacac gcataaccat aaagatacga tctgccactt cttcttgtag
     7021 gactgccaaa cgcttagcgt attcaaggac agcttcttcg ttgtcagatg agcatggccc
     7081 gattaccaag agaattcgct ggtcttctcc acgtataatg gcttctagct cttgatctcg
     7141 ctgtgatttc ctctccaaag cctgaccttc taattttgac aaggcacgaa cttcttctat
     7201 atttatttta gagctttttg ctgtaaatac cataactcat ctccttataa agcaaacgga
     7261 tacccagtaa aaatttactt ttcacaagat atccgcctct aaactatctc attttattgt
     7321 cttttaccgt gacagttttt aaatttctta ccagaaccac atgggcaaag ttcattgcgt
     7381 ccaatctggc tcaaatccaa atcttctggc atacttgctt ggtgagcagc gatattgcga
     7441 gtcgctgttg tactgatatg acgttctgcc tgtggtcttt cttgttcatg aatttgtgct
     7501 ttcatcatca agcgtgtcac atcaaactca atcgaaccaa tcatatcatt aaacatacgg
     7561 aaaccttctg cctgatactc aacaacaggg ttgttctgag catagccacg aagtccaacc
     7621 gcgttacgca attgatcaag ggcatcgata tgatctgtcc acttgttatc caccactcgt
     7681 agaatcaaaa ctttttggaa ttctttaact gcttcttcat cgcgtagttt tgaaacctga
     7741 ctatcgtaaa ccttcaaggc acgttggaaa agctcttcct tgatggcctt atcagacaag
     7801 cctgacaagt cttccatcgt aatagaatct tcaggaagca agttgtactt agcaaagttc
     7861 aaaattgcct ctagtttttc atcttgtttg gcacgcgcat gaccatcaac gacacgttca
     7921 agcgtgcgct taatcataga ctgaatttca ggtgccaagt cacggtctgc agtaatgaca
     7981 tcataacgtt gagtatagat aatctcacgt tgttcacgca tgacatcgtc gtattgaagg
     8041 acttgtttac gggtatcgta gttatttcct tcgacacgtt tctgagctgc ttcaacctga
     8101 cgcgtcaaca tgcgagactc aatcgcctct tcagacatgt tcaagcgttc aaagattccc
     8161 ttcaagcgtt cagaaccaaa acgtttcatc aaatcatctt caagagatag gtagaattgt
     8221 gactcacctg gatctccttg acgacctgaa cgtccacgaa gctggttatc gatacgacga
     8281 ctttcatgac gttctgtacc aataacacaa agtcctccaa gttcacgaac accttcacca
     8341 agcttgatgt cggtaccacg acccgccatg ttggttgcga tggtaacggc accacgttga
     8401 ccagcattca tgatgatttg ggcttctcta tagtggtttt tggcattcaa gacttcgtga
     8461 ggaacaccag ctgcaaccaa tttcttagaa atgtagtcac tagtttcaac cgctactgta
     8521 ccaaccaaga caggttgacc cttttggtaa cgagccttaa cgtcttcgac aaccgcttta
     8581 aacttagatt ctatacttgc ataaagaagg tctgagtggt caatacgttg aacaggacgg
     8641 tttgttggga ttggaataac acgaatgttg tagatttcac ggaattcttc ttcctcagtc
     8701 ttacctgtac ccgtcatacc agacaatttc ttgtacatac ggaaaaggtt ttggtacgtg
     8761 attgaggcag atgtcttggt ttcatcctgg attggcacac cttctttggc ttcaatagct
     8821 tggtgcaatc catcagaata acgacgacct tccatggtac gacctgtaaa ttggtcgaca
     8881 atcaagattt cttgctcttc gctcaccaca tagtcaatat cgagaagcat gatgtagttg
     8941 gcacgaaggg cgttatcgat aaagtgggtc aaagccacgt tttcgatgtc atagaggttt
     9001 tcaagtttga agtagctttc agccctgtca atccctgaat cagacaaacc aatagtctta
     9061 gactgcacat cgatgatgta gtcatctttg ttcaaagatt ttacatagtg gtctgccatg
     9121 tgatacaact gactggtttc aaccgcattg gcacctgata caatcaaagg tgtacgagcc
     9181 tcgtcaatca agatagagtc aacctcatcg accaaggcat agttaagcgg acgttgtacc
     9241 atgttttcag cgcgaacgac catattgtca cgaaggtagt caaatccgat ttctgagtta
     9301 gttgagtaag taatatcaca ctcataggct tcttttttct ccattggaga tttggtagcc
     9361 aagttaatcc ctactgacaa accaagccaa gagtacaatt cacccatctc agtcgcgtca
     9421 cgttctgaca ggtattcatt aaccgtaact acgtgaaccc ctttacctga aagggcattg
     9481 aggtataccg gcatggtcgc agtcaaggtt ttcccttccc ctgtacgcat ctctggcacg
     9541 tcaccatggt gaagaacaat cccccccatg acctgaacct tataagggaa gagacctagg
     9601 acacgtttgg caccttcacg gacaaccgca aatgcttcgt aaagcaatga atccagtgat
     9661 tctccatttt gataacgttc cttaaattca actgtttttg cttttagttg gtcgtcagtc
     9721 aaagcagcca tttggtcttc gtatttgaaa accttgtcag ccatcttttc cagacgacgg
     9781 atttctcctt tatcattttc gataattgtt tttaaaatat tagccatgtt tttccttact
     9841 ttaaattccg aatattttag aatgttcctt taattttagc acaattactg attattttca
     9901 aggaagaatc cccattttga aaaggaaaaa gaggttagtt tccaagctaa cctctctgac
     9961 ttttatgata ctttaattgc caagaatcgg caaaatagca aataggataa ataagttaat
    10021 ccaaagagaa agacagcaga tcaatccaaa aacaaagaga ctgactttct tggacagcaa
    10081 ggccatcaaa atggacagaa tgccaaaaac tagcaagact ttctgtatgc tgaagaggtc
    10141 aatcttcccc ccccccagaa tcggactgcc ccaaggaaga aagaagaaag caatccagat
    10201 caacagaact aaaccaatat agaccttaga atagcgtgta ataaatgatt ttagatgtgc
    10261 cataagccat ctcctaggat tgtatatcct ttacatttgt atatgtccat tttcgacaac
    10321 taatacatct gtacaaaggt ctgaaatatc ttccgatatg tgcgacgtca ggataaccag
    10381 accattttct tttttcaggt aagataaaat gacctgtttg gttaacctca cacttttctc
    10441 atccaaagca ttcataggtt catcgagaaa gagtatagaa ggagaggaaa taaaggcttg
    10501 aatcaaggcc attttttgct ttgttcccaa ggataaatgc cggtattcaa cgtcttcaaa
    10561 ttcctgtaaa tcatagtatt gaatccaata ggcaattctt ttttccgtaa ctttagatga
    10621 aaaatacctt aacagttcca aattttctct cagggataaa tgagataaaa actcgacttt
    10681 ttcaattaaa attcctgcat cctgaatata atgatttttt atcccgtaaa ctttaccatc
    10741 ttgaagaact tttcctttgt caagcttaat ataaccagca agtatcttta aaagaaccgt
    10801 cttgccagat ccattatcac ctttaagtcc ataaattttt cctgattgaa acaccaaatt
    10861 caactgattt aaaataggtc ttttcccata aattttctgt ccatttataa tttcaagtct
    10921 catcgtttat cctttcttaa atttctcttc caagcgacta agaatcaaca taactaataa
    10981 gcttaagagt actaaataca ctgttacaat atgatccatc atccattctt gtcccacaaa
    11041 tgccaaaaaa tagagaaaaa aagaaaaacc agcgcccgca ctaatcagtg ctatcagata
    11101 agacagtagt aagtacaaca tcattaactg agcaagtaaa aagaaaagtg cgactgtttt
    11161 gaaatgaatt cctagcggaa gtaaaccaag aaaccagaca aacaaatctt gagtaaaaaa
    11221 tttagaaatg acaaccaatc gtttccttgt ataatcgaaa aaggagcttg attgatagcg
    11281 aatcaagtga tggtaatggt ctgccaaatc actttcaagt aaaatgacag agagccatcc
    11341 taccatgaaa agcgaaaggt ttaacaagag tttggggatt tctaaattcg cttcagaata
    11401 gtcattatag gaaaaaattg aaatcaattc tctcttgaaa aagataacag catcctgctt
    11461 ttgaaccgct gttgacaata gatagtttat caaaatcatc atcagaacta tacgaagtag
    11521 taaaacgatc tttctcttta gccaaatatt gttaaaattc ttaaacatta tcttcatatt
    11581 ttttaagtac catataaggg acaacataaa ggatataagg agtaaagagt ttcatcaaac
    11641 ttacatcccc atagctagct tgcatcaaac tcgtcatagg aaccatatag taaggcaagg
    11701 cactatagag cagcatagaa ccaagccaaa gaaacatcaa ataggtgatt gccgaacgag
    11761 tcacattccc cacataatca actatttgta aaaaatagat tgcattgatg aaaataccga
    11821 ttagtaggac acaagtaaag aacaaatagc tttttatctc tccatctagg agtctttgta
    11881 aaccactccc atcagaaaat agagaattcc attcaagagg agaaaaagtc ccaaagaaat
    11941 aggttataat tgcaattatc agcacagtca ctaaatatat caaacaaggg atacttgcaa
    12001 cttgcaaagt caactttctt tttaaccctt gatagctcac ttctcttcca atactcaatc
    12061 gtaaaacttt atttttcagc tcaatatatt gaaaacctag caaaacaatg atgattggaa
    12121 taataaatga ttgataaaaa cctagattga actggagaat acgaaaatct aatgctgatt
    12181 ttaataagtc atttttaatt gcttgtccat cgaatttagc tagatcgggc gcatgaatat
    12241 caaaaaagaa ataagtcatc aaaacatcac gataaaccaa agcaagaaaa agcaaagtaa
    12301 gcaagacata aacaaattta tgccttgcca aagttaagag aggaatcttc ataagccacc
    12361 tcctacaaat agaaagtaat ataatactca atgaaaatca aagagcaaac taggaaacta
    12421 gccgcaagtt gctcaaagca ctgctttgag gttgtagata agactgacga agtcagttac
    12481 atatataatc caaggcgacg ttgacgtggt ttgaagagat tttcgaagag tataaatcaa
    12541 tgccttccgc ctttagactt ccctagttcc cgtctcaagt caagcatttt tttgaaacag
    12601 atatagtcta accagtcact agcaaaagcg ataagtagta ataatagcca aataccccat
    12661 aacttgatat ctgtcaaatt tctcaagacg atattgaaaa acagaactga aaaaactgtc
    12721 caagcaaggc taaaaagagc atagagggtg atgtaaatcc agtaaaaata gtaaaaaatt
    12781 gggaaaatct tactatctct gtttgccttt tcaatccagc tgaaaaagta aaaacagggc
    12841 aataagatta tcattttaaa caagtattcc atcacaaacc tcctctttta aattgttttc
    12901 tttagtttcg ttctattaaa tgttattacc aatataaacc ttggaatagc gtgtaataaa
    12961 tgattttaga ggtaccataa gccacctcct acaaatagaa accgatataa atcaatgcct
    13021 tccaccctta gacttcccta gttcctgtct caagcgaaac atttctttga aacaggaata
    13081 agttaaccaa ttcataccaa tagctagcag aataaaaaga aaccaaatgc cccataactt
    13141 gatatctgtc acatttctca agacggtatt gaaaaacaga actgaaacaa ctgtccaagc
    13201 aaggctaaaa agagaataga aggggatgta aaaccagtaa aaataataaa aaattggaaa
    13261 aaacttacta tttctgttgg ccttctcaat ccagttatca aaataaaagt acggtgctaa
    13321 aagtaagaat ttaaacaaat gttccatcac cgacatcacc ctccttcttt tgatagcgtt
    13381 ttctattatt ttattatatc aaaaaaatcc ggaactgtca ttccagattc tactttttta
    13441 tttgcgtttt cttgcgatga gatgaatcgg tgttccctca aaaacaaagg ccttgcggat
    13501 ttgattttcc aagaaacgca ggtaagaaaa gtgcatgagt tcttcttcat tgacaaagat
    13561 gacaaaggtt ggtggtttgg ttgccacttg ggtcgcatag aaaatcttga gacgttttcc
    13621 tttgtctgtc ggtgttgggt tgatggcaat ggcatccatg atgacatcgt tcaagacagc
    13681 tgatggaata cgtgtatttt gactttcgct gatttgctta atcatctcag gaagtttgtg
    13741 gagacgttgc ttagtcaaag ctgatacaaa aataatcggt gcataaggca ggtattggaa
    13801 ctgctcacgg atatcttctt cccagttttt catggtatgg ttgtcttttt caagcgtatc
    13861 ccacttgttg actacgataa tcattccttt accagcttca tgggcaaatc ctgcgatacg
    13921 cttgtcgtac tcacgaatgc cttcttccgc attgatgacc atcaagacca catctgaacg
    13981 gtcaatagca cgcatggcac gcataacaga gtatttctca gtattttcat aaaccttacc
    14041 agacttacgc ataccagccg tatcaatcat ggtaaactct tgaccatctg tatctgtaaa
    14101 gtgggtatca atagcgtcac gagttgttcc agcaacagga ctggcaatga cacggtcttc
    14161 tcccaagata gcattaatca agcttgattt tccaacgtta ggacgaccaa tcaagctaaa
    14221 cttaatgaca tctggatttt cttcttcata ttcatttgga aggttttcca caatcgcatc
    14281 tagtacatcc cctgtaccga taccatggac agatgagata ggcagtggtt cacccaaacc
    14341 gagagcatag aaatcataga tatcatttct catctcaggg ttatccacct tgttgactgc
    14401 gaggataact ggtttgtggg tcttataaag cttgcgggct acgtattcgt ctgcatcggt
    14461 aattccttcc ttaccggaca cgacaaagac gataacatct gcttcttcca tggcaatttc
    14521 tgcctggtgc ttgatttgtt ccatgaaagg agcatcgaca tcatcaattc ctcctgtatc
    14581 aatcatgcta aaagaacgat tgagccactc acccgttgca taaatacggt cacgtgtcac
    14641 tccttcgaca tcttctacaa tggagattcg ctcaccagcg atccgattaa atagggttga
    14701 tttcccaaca ttgggacgtc ctacaatggc aatagttggt agggccataa tttctcactt
    14761 tctacaataa tttcttctgt tcaagatttt ttctagttga gcttggttca gcttgaccaa
    14821 actgttctgc taggcgctga ctccagcttg tggtcgcacg cccccccagc atagtcagcc
    14881 tgcacacggt cataagcttg gattgtctca gttgactgtt cttggtattc ttcctcaaag
    14941 acaacattct ctagtggcag tctcggtttc acatcatgat gttgatttgg cacacccagt
    15001 gccatcccaa agacagaata ggtgtagtca ggtaggttaa agagctctgc cacttcttca
    15061 gacttgtatc gaaccaaacc gataatcaca ccaccatagc ccaagctttc agctgccaac
    15121 aaggcgtttt gtccagcaag agctgcatcg accgaactaa tcaagagacc ttccacacct
    15181 tggggttgga aggtgtcggt atgaagtcgg gctccctttt ctgctcggtt caaatctccg
    15241 acaaagagaa ggaaaacagc agactggcga atggcttctt gaggtaccaa ttcatacaag
    15301 gcatctttct tctcttgact tcgtaccaca atcacagagt aggattggaa attcttccaa
    15361 gatgatgcca tctgggctgc tgtcaaaatc tcatttaagt ctacttgggg aatttcttgc
    15421 tctttaaacc tgcgcactga agtatgagcc ttcatcaatt taatggtttc tgtcatcgac
    15481 ggtttactcc ttctaaacga gtctcctcag ccaaataacg gatgcgttcc atgacccgtc
    15541 tggcttccca ggtttcgtca tttccatgtt tcactttcgc aaaatgcttc tccaaatctt
    15601 caaagttgaa gttggatgtg aaaaaggtcg gtaaattttc ctgcatccga tattggagaa
    15661 tgacctgcag gatttcgtca cgtacccaaa cggttgattg ctcggcgcca atatcatcta
    15721 aaatcaggac ctcagacagc ttaatctcat ccaccaaggt cttaacattg ccatcactga
    15781 tagcattttt gacatcaatg acaaagctag gatagtggag gagagttgat gaaacaccac
    15841 gtttttctga taaatcatga gctaaggccg ccaccatgaa acttttaccc acaccaaagt
    15901 ctccatataa gtaaagacct tttcgaatag ctggatattg ctccacgaag gctagtagct
    15961 tttcaaaaac tggtaagcgc cccaaatcat ccaagtcaac ttgagccaaa ctagctttct
    16021 tgagactggc tggtagattg attaacttga gacggttctt aatagccgct tctttttcag
    16081 ccgcgattag ctcaggagtt tcttcatatg aaacatctgc atagccatga ttcttaacca
    16141 aaatcggctt gtagcctttg gcaatataat ccgtatcccc acggagaaac ttgtcacgct
    16201 cggtgatgta ctgattaaac ttggagatac tgcgatttaa ttcctctgga gtcaaggatt
    16261 cttgctggat aaaagccgca acatcagggt ccttcatgat tttctggacc aaatcttgat
    16321 aataaaaacg gctgggttga cgtttgagta cgtctccgac actttccatc taatctcctc
    16381 ctttttctaa tcgagctaat agttcttgct tcttacgttc tagttccaga cgagtttcct
    16441 cgctggtttc attcttatat tcaggattac tccatttagg aacattggtt tttactgggg
    16501 cagtctgatt ctgtttttgt gtttttgctt tctgtcctcg ctcacggatg cgcaagactg
    16561 ccttttctgc cgaatgaatc ttttgatagg catagtcatt ggctaccttc atggcatatt
    16621 tctcattgat atttgccgaa tcgaccttat taaaggtcaa taaaagaatg atattgatga
    16681 cttcgtccag caagcccaag ccagccatct gttgcaagag ttctctttct gtttgggtaa
    16741 tggttccctt gcgtgtttgc ttgatttctg ccaagaactg cagggcagtt ttacttttgg
    16801 cttctttgat aatggttgtt tccttaagac taaagtcaga ggaaactggt ttttgagcaa
    16861 ttttttcacg catgcgtttg gttgaaataa cctgagaaac agctgttgac ttggccaatt
    16921 gataggtttc aaaccaagtc catttcttct cctcggcaat agcaaagagg tttaagacat
    16981 cggactgctc atccgcaaaa cgaagtccat ctcgagccat cagctggcga aaatgttcca
    17041 agtcaaaatc attggccact ttcttcttga gaccaaggtc ttcttgactg cctagttctg
    17101 ccaattctgg aaagacttga ttgagtgaga caggtatttc ttcaccatca gcactttcaa
    17161 ctttcaaatc ctccacagca gagtcgccaa tctttttctc taagagtctg cgataaacag
    17221 gatgctccaa gaagtcttga ctagatagag gagcatggag ggctagctga taaacatccc
    17281 ccttttgata gagggtcaag agattaaaag cagataagat tttcaatgat tttatcagtc
    17341 tatccatccc aaagttgaga tgattgagga tacttgaaaa aagatattcc tttctaccat
    17401 tatcccaaaa actgattgta taaagataaa ggctcagtgc ctcctgaccg ataatcggga
    17461 ggtagcactg taccagagat gaggtatctt gcgacacccg attattcttt agataagaaa
    17521 aacggtcaat tggcttcatt tatctttcct ttttcttttt agaggactgg gtgatttgtt
    17581 ggagcaagct ctctaactca ctgacatcct taaaactacg atagacacta gcaaaacgta
    17641 cataggtaat ctcgtccaat tcagccaact cctccatgac gagtgaacca atgtcctcac
    17701 tttgaatttc attttcattt cgaccacgga gtttctgttc gatacgattg actaccatgt
    17761 tgatttcatc acttgacaca ggacgtttct gggctgagcg gataatccca ttaaagattt
    17821 tatctctgga gaattgttcc cgtgtaccat cttttttaac aaccactaag gttctttctt
    17881 ctactcgttc gtaggttgta aaacggtgtt ggcattcgtc gcactcacgt cttctacgaa
    17941 tggtgttccc ttcttctgct tggcgactat cgataacact tgacttggta gccccacatt
    18001 ttggacaacg catcctttcc ctccttatcg ttttcttttc attataccat tttttaagcg
    18061 attcccaaaa caattcttct ttttgcttga caagtttttt gttttgttgt attatttaat
    18121 taagacaaaa ggataagaga aaggagacta agatgtcctg gacatttgac aacaaaaaac
    18181 ccatctattt acagattatg gagaaaatca agcttcagat tgtttcccat acactggaac
    18241 ccaatcaaca acttccaacc gtgagggagc tagctagcga ggctggtgtc aatcccaata
    18301 ccatccaaag agccttatca gaccttgaac gagaaggatt tgtctacagc aagcgaacaa
    18361 ctggacgatt tgtgactaag gataaggagc taatcgccca gtcacgcaaa caattatcag
    18421 aagaagaatt ggaacacttc gtttcctcca tgacccattt tggctatgaa aaagaagaac
    18481 taccaggcgt agtcagtgat tatattaaag gagtttaagc ctatgtcatt actagtattt
    18541 gaaaatgtat ccaaatcata tggagcaaca ccagcccttg aaaatgtttc tcttgacatt
    18601 ccagctggaa aaattgtcgg ccttcttggg ccaaacggct caggaaaaac aaccctgatt
    18661 aaactaatta atggcctctt acaaccagat caaggacgtg tcctcatcaa cgacatggac
    18721 ccaagcccag caaccaaggc cgttgtagct tatttgcctg atacgaccta tctcaatgag
    18781 caaatgaagg tcaaagaagc cctaacctac ttcaagacct tctataaaga tttcaatctt
    18841 gaacgcgccc atcatctact tgcagacctg ggcattgatg aaaatagtcg tctcaagaaa
    18901 ctatcaaaag gaaacaaaga aaaggttcaa ctgattttgg ttatgagccg tgatgctcgt
    18961 ctctatgttt tggacgaacc cattggtggg gtggatccag cagcccgtgc ttatatcctc
    19021 aataccatta tcaacaacta ctcaccaact tctaccgttt tgatttctac ccacttgatt
    19081 tctgatatcg agccaatctt ggatgaaatt gtcttcctaa aagacggaaa agtcgtccgt
    19141 caaggaaatg tagatgatat tcgctacgag tcaggtgaat ccattgacca actcttccgt
    19201 caggaattta aggcctaagc aaaggagatt atttatgttt tggaatttag ttcgctacga
    19261 atttaaaaat gttaacaagt ggtatttagc cctctacgca gccgtgctag tcctttctgc
    19321 cctcatcgga atacagacac aaggctttaa aaatctacct taccaagaaa gtcaggctac
    19381 tatgctactt tttctagcta cagtctttgg tggcttgatg cttacacttg ggatttcaac
    19441 cattttcttg attattaaac gcttcaaagg tagtgtctac gaccgacaag gctatctgac
    19501 tttgaccttg ccagtttctg aacaccatat catcacagcc aaactaatcg gtgcctttat
    19561 ctggtcattg attagcaccg ctgtattggc tctaagtgct gttattattc tggctttaac
    19621 agctccagaa tggattcctc tttcttatgt gattacattt gtagaaacac atcttcctca
    19681 gatctttctt acaggtatat ccttcctact aaatactatt tcaggaatcc tctgcatcta
    19741 cctggctatt tccattggac agcttttcaa tgaataccgt acagcactcg ctgttgcagt
    19801 ctacattggt atccaaatcg tcattggatt tattgaactt ttcttcaatc ttagttctaa
    19861 tttctatgtc aattcactgg taggactcaa tgaccatttc tatatgggag caggtatagc
    19921 cattgttgaa gaactcatat tcatagctat cttttatctc ggaacctact acatcttgag
    19981 aaataaggtt aatttgcttt aaataatttt tacctagata tgtaacatac tcatagaaca
    20041 aaagagacca ggcaaaaagt ctttacaatt agaaaacgca tagtatcaag tgttaaaaat
    20101 ccttgatatt atgcgttttt tgtgagctga cttatttcct ttcactatat cgcaaaatga
    20161 aataagaacg gaacgatggg attttggaat tcaaatcaat ttataagaat gttttagaag
    20221 taatattatc ctattccaga ttcagttcac tatacaattg agttttcaag caacctgttt
    20281 acataatgtg tacataatta ggttcgtgat tccacccttt tcacctttaa aaacctcgct
    20341 ttcgcaaggc tcttctattt ataagataag gcacgtttaa aggttttcca aatccctaaa
    20401 tcatccgttt gaagaacgag actagcatac atgcgtccga taaatcctgt tgctaccacc
    20461 gcaaaaatca ctgtaatagc aagtgaaatc catgcttccg ctccctccgc atagccatta
    20521 atcgttcgaa acggcataaa gaaggtcgaa ataaagggaa tataagaacc aatcttcaag
    20581 aggagattgt caccagctgc acctagagct gtcactcaaa aaaaaccacc cataatcaaa
    20641 atcatcaaag gcgacaaggc tttccctgag tcttcaggac gagaaaccat agatcctagg
    20701 aaggctgcca agactacgta catgaaaaga ctgatcaaaa taaagagcaa ggtattcagt
    20761 gagatagcat ctcccaagtg atccaaaata ccagactgag ccaagaatgg caaatcttta
    20821 aagagcaaaa cggcagccag accacctaca acatagatcc caatatgcgt taaaatcact
    20881 agaaacagag ccatcatccg cgcatagaaa tagtgacttg cccttatgct agaaaagacg
    20941 acttccataa ttttggtgcc tttttcactg gcaacttcct gagctgttac acccgcatag
    21001 gtaatcagaa tcatataaag aaagaatcct aaggcacctg ctgcaattgt ttgaataaac
    21061 tttttatttt ccttggcttc atcaatcttt tctgtgaatt gaattgtctg cgctaagcgt
    21121 ttttcctgct cttgagacaa ggaagcagtt gaacgattaa gctgattttg cagttcattg
    21181 agtgtacctg taacctcaaa tttaattcca ttttcaagcg atgtttcgcc atgataaact
    21241 gcctttagaa cactatcttc ttgatcaatg gtcaaataac cttttaattt ttcttcttta
    21301 attgcttctt tggcacttgc ttcgtcttta tagtcgaagt taacaccatt tacattcttc
    21361 agtccttctg ctacagatgg cactgttgtc actactgcca ctttattatt tttagccata
    21421 gaagaacctt ggagatgccc aattcctaca gagattccta aaaagaggaa cggcgaaatc
    21481 accataaaga agaaactcca tgactcgaca tgtcgaagat aggtttcctt gattacaacc
    21541 cacatatttc tcatacttcc actcctgatt ctagtttaaa gatttcatcg atagttggcg
    21601 cttgttggtc aaatgttgcg atatattgac cttgagtcaa gattgggaag agttcccttc
    21661 cagcgctctc atcctccaaa atcaatttcc aactgccttg tttggtcaag ctcacctgtt
    21721 tgacatgagg aagattttcc aattcttcct tgcttcgttc acttgaaaca aagagacgcg
    21781 ttttcccgta ttgattgcgg acatcctgaa ctggtccgtg caagaccaca cggccatctc
    21841 gaatcatcag aatatcgtca caaagttcct caacattggt catgacatgg tcagaaaaga
    21901 taatggttgc tccgcgctct ttttcctgaa aaatgacttg tttgagcaat tctgtattaa
    21961 ctgggtccaa tccactaaaa ggctcatcca agataatcag gtctggttca tgaatcagag
    22021 taataatgag ctgaatcttc tgctgatttc cttttgacag actcttgatt ttatctgtca
    22081 gctttccttt tacttccaac ctcttcatcc attgagggag tttttctttg acttctttgg
    22141 catccatgcc ttttagagtc gccaagtagc gaacttgttc aagaactgtc aatttaggca
    22201 tgagactgcg ttcttcaggc agataaccaa tccgagcata gatctcctga cgaatatcct
    22261 gaccatccag accgatttct ccctgatatt ctaggaattt taaaatacta tggaaaatcg
    22321 ttgtttttcc ggcaccattt tttccgacta gtcccaaaat acgacctggt cgcgcttgaa
    22381 agtcaatacc aaacaaaact tgcttggatc caaaactttt ctctagactt cttacttcta
    22441 gcatctttca cctccgaaat ttcttgcact cattatactc ctttttgata gcctttacaa
    22501 tgttttttgt ccatttttag aagactattg ctgtgtaaaa tatggcctgg agcactttta
    22561 tactcaatga aaatcaaaga gcaaactagg aagccagccg tagactgctc aaagtacagc
    22621 tttgaggttg cagataaaac tgacgaagtc agctcaaaac actgttttga ggttgtggat
    22681 agaactgacg aagtcagtaa ctatatctac ggcaaggcga agctgacgtg gtttgaagag
    22741 attttcgaag agtattagtg ataaatccat tatacagcag caaacttaat ttataccttc
    22801 cgctcctcaa ctgtctattt ttaatcctga attgttattt gagtaactcc tttttcctcg
    22861 taaagttttc ttcctctaaa acttctggaa aaaggctaat agtttcagac aacattttta
    22921 taagaaacaa gttcatctgt catttcaaga aggagtaatc ctttatctac taatggacgg
    22981 aacagaattc aaccgcttgt cccatatgtt ttctaaggat tatatagtaa aatgaaataa
    23041 gaacaggaca aattgatcag gacagtcaaa ttgatttcta acaatgtttt agaagtagat
    23101 gtatactatt ctagtttcaa tctgctatat ctattatgca cacccctata ggatctaatg
    23161 aaaatcacaa caggctcatt catagatagt tacctcagga aactaagaaa acgactacaa
    23221 aggaagtcgc attcatcgaa aagtggatta acaactatcc taaaaaatgc ttgaactaca
    23281 agtcccccag agaagacttc tggatgacta acttgaactt gaaatttagc aataattaat
    23341 tcaccatcta actatattta gtaattattt cagaactgat taatattaaa attaactaac
    23401 aattcaaagg attcatacta gccataaatt acgtccatca gagagagact cttactactt
    23461 ttagatttta gtctttctag cttcagaata catctaaact ttagggaaaa tgactattcg
    23521 aaagcgcgaa tgcctcaaaa ttatctcaga taagctattc gaaacttaga atgcttttaa
    23581 atttatggaa ttgcgattat ttgaaaccta gaatgcatat aacctttagt tgacagacct
    23641 attctaagtc tcgaagggct atttactttc tattccttat caaaaaagac tcattccccc
    23701 tttctcctcc aaaatatggt atagtagaaa tatactatct atgaggagtt tacatgtcac
    23761 aggataaaca aatgaaagct gtttctcccc ttttgcagcg agttatcaat atctcatcga
    23821 ttgtcggtgg ggttgggagt ttgattttct gtatttgggc ttatcaggct gggattttac
    23881 aatccaagga aaccctctct gcctttatcc agcaggcagg catctggggt ccacctctct
    23941 ttatcttttt acagatttta cagactgtcg tccctatcat tccaggggcc ttgacctcgg
    24001 tggctggggt ctttatctac gggcacatca tcgggactat ctacaactat atcggcatcg
    24061 tgattggctg tgccattatc ttttatctag tgcgcctata cggagctgcc tttgtccagt
    24121 ctgtcgtcag caagcgcacc tacgacaagt acatcggctg gctagataag ggcaatcgtt
    24181 ttgaccgctt ctttattttt atgatgattt ggcccattag cccagctgac tttctctgta
    24241 tgctggctgc cctgaccaag atgagtttca agcgctacat gaccatcatc attctgacca
    24301 aaccctttac cctcgtggtt tatacctacg gtctgaccta tattattgac tttttctggc
    24361 aaatgctttg acacgtaaaa aatccgtttg gtttcccaag cggattttgt gctttatttt
    24421 gaaacttctt ttgcaagaac aaagttccca agtgtggcag aaccatttcc tgcgactgct
    24481 ggcgtcacga tatagtcacg cacatctggt actggtaggt aaccattaag aagagatgta
    24541 aatttctcac ggacacggtc cagcatatgt tgttgagcca tgacccctcc accaaagaca
    24601 atcacgtctg ggcggaaagt cactgtcgca ttaaccgcag cttgagcgat atagtaggct
    24661 tgaacatccc aaacagggtt gttgagttca atagtttccc cacgtacacc tgtacgagct
    24721 tccaaacttg gaccagctgc atagccttcc agacatccct tatggaaagg acaaacaccc
    24781 ttaaactctt tttcaatatc cattgggtgt ctagcaacat aataatgacc catttcaggg
    24841 tgacccacac caccgataaa ctcaccacgt tggatgacgc ctgcaccgat acctgtaccg
    24901 attgtgtagt aaaccaagtt ttcgatacga ccaccagcat tgttacgggc aaccacttca
    24961 ccgtaagcag agctgtttac gtctgttgtg aagtacattg gcacgtttag ggcgcgacga
    25021 agggcaccaa gcaagtccac atttgcccag tttggttttg gagtcgtcgt gataaagcca
    25081 taagtttttg agtttttgtc aatatcaatc ggcccaaatg aaccaactgc aagaccagca
    25141 aggttatcga attttgagaa gaactcaatg gttttatcga ttgtttcgat tggagttgtt
    25201 gttggaaatt gtgttttttc tacaacgtta aagttttcat caccaacagc acagacaaac
    25261 tttgtaccgc cagcttccaa gcttccatat aattttgtca tgataaacct cttgttttta
    25321 ttttctttat tatagcatac ttcgaaagtc taaatgtctc tattttttag attttcctct
    25381 gtaaatctta ctatctaata aaaacgaaca aacatgtcat ttgttcgttt tcacattaga
    25441 gaggattgat tagattttca cttcgatcac agcatccccc ttcgcaactg aacctgttgc
    25501 gactggagct actgaagcgt agtcagctgt atttgtaacg ataaccattg ttgtatcatc
    25561 aagtccagct gtagcgattt tatttgagtc aaatgttcca agaacatcgc caactttcac
    25621 cttatcacct tgagcaactt ttgcttcaaa accgtcaccg ttcatagata cagtgtcaat
    25681 accaacatga atcaaaactt cagcaccatt tcttgttttc aaaccaaaag cgtgccctgt
    25741 tggaaaggca attgaaactt cagcatcagc tggtgcatag accacgcctt ggcttggttt
    25801 cacagcgata ccttgtccca tagctccact tgagaagact gggtcattga catcagcaag
    25861 agcgacaaca tcaccgacga taggagttac aagtgtttca ttttgaagag ctgctggcgc
    25921 aacttcttct ttttcttcag ccacttcagc ttgttttgca gctgcagttg cgtctacttc
    25981 atcttcgtaa ccaaacatgt aagtaagagc aaaaccaagg gcaaatgata cagctaccat
    26041 aagaaggtat tgtggaagtt gtccgttacc aacataaagc attgtaccag ggatgatggt
    26101 gataccatta ccagtaccag caagtccaag gatagaagcc aatccaccac cgattgcacc
    26161 agcaatcaat gaaaggaaga atggtttacg gaagcgcaag ttcaccccga agatagcagg
    26221 ctctgtaata cctaggaagg cagaaagagc agccgggaaa gcaagtgttt tcagttttgg
    26281 attttttgtt ttaacaccaa ccgcaacagt agcagcacct tgagctgtca tagcagctgt
    26341 gatgatagcg ttgaatgggt tagcatggtc agcagcaagt aattgcactt caagcaagtt
    26401 gaagatgtgg tgcacacctg acacgacgat caattggtga accccaccaa tcaagaaacc
    26461 accaagacca aatggcatgc taagaatcgc ttttgtagca ataaggatgt agttttcaac
    26521 aacgtggaaa actggtccaa tgacaaagag tccaaggata gacatgacca aaagtgtcac
    26581 gaatggtgtt accaagaggt caatgacatc tggaacaacc ttgcggacag ctttttcaaa
    26641 tttagctccg acaaccccga tgatgaaggc tggaagaacg gaaccttgca aaccaacaac
    26701 agggatgaaa ccaaaaaagt tcatcgctgt tacttcacca ccttgagcaa ctgcccaagc
    26761 gtttggaagt gagccagaga caagcatcat accaagaacg ataccaacgg caggatttcc
    26821 accaaataca cggaaggttg accacacaac caaacctggc aagatgatga aggctgtatc
    26881 tgtcaagatt tgtgtgtaag ttgcaaagtc acctggaagt ggcatttcaa gagcgttgaa
    26941 aagaccacgc acacccatga agagacctgt cgctacgata actgggatga ttggaacgaa
    27001 aacatcacca aaagtacgga tagcacgttg gaaccagttc ccttgtttag caacttctgc
    27061 tttcatgtca tccttagatg atgttggtaa tccaagtaca acaacttcat cgtacatttt
    27121 gttaactgta cctgtaccaa agataatttg gtattgccct gagttaaaga aagcaccttg
    27181 aactttttcc aagttctcaa tcacttcttt attgattttc tcttcatctt tgaccatgac
    27241 acgtagacga gtcgcacagt gggcaacact attgacattt tcacgtccgc ccaaggcatc
    27301 gatgactttt tttgcaattt cctgattgtt catttgcaaa aatctcctta tataacattt
    27361 tgttcttgtt tgaaagcgat tttattcgcc cttacgacta ttattttatc atgttttaaa
    27421 aatatgtcaa gcgttttgca taaaaatatt ctatccactt agtgggcaag ctttagattg
    27481 attgtttttg actgtttcat caggaattcc ttgaaaaata agtttgaaac cttggttaaa
    27541 aagtatttta tttcattatc tttcacattt tcgtaaaaat ttgattgatt tcctgtattt
    27601 attttatgat aatcgtttga cagtttttcc tcttttttaa cataaaaggc ttgcattttt
    27661 tatcgaaaac agttactatt aaaagtgata agatttttgg aggaatgaat ggaatggaca
    27721 actgagcgtc gttacagact ttatcaagat tggacgcaag aagaaattca acatataaag
    27781 gaaaatatgg cacaatctcc atggcatact cattaccatg ttgagccaaa aacaggactt
    27841 ctcaacgacc caaatggctt ttcttacttt gatggcaagt ggatcctctt ttaccagaat
    27901 tttccttttg gtgcagccca cggtttgaaa tcttgggcac agctagaaag tgatgatttg
    27961 gttcacttta aagaaactgg aatcaaagtt ttaccagata ctccattaga tagccacggt
    28021 gcctactctg gttctgccat gcaatttggc gataacttat tcctatttta tacaggaaat
    28081 gttcgcgatg aaaactggat ccgtcaccca taccagatcg gtgctttgat ggacaaggag
    28141 ggtaagatta caaagattga caagatcttg attgaccagc cagcagactc tactgaccac
    28201 ttccgcgatc cacaaatttt taactttaaa ggtcaatact atgctgtcgt cggtggacag
    28261 gacttggaga aaaaaggctt cgtccgtctc tacaaggctg tcaataacga ctacacaaac
    28321 tggcaagcag ttggcgacct tgactttgct aacgaccgta ctgcctacat gatggaatgt
    28381 cctaatctga tctttgtaga ggaacagcct gtccttctct actgtccaca aggattggat
    28441 aagaaagttc tagactacga taatatcttt ccaaatatgt ataagattgg ggcttccttt
    28501 gaccctaaaa atgccaaaat ggtagatgtg tctcaacttc aaaacatgga ttacggtttc
    28561 gaagcctatg caactcaagc cttcaacgct cctgatgggc gtgctctagc agttagctgg
    28621 cttggtttgc cagatgtttc ttacccatct gactgttttg atcaccaagg aaccttctct
    28681 ttggtcaagg aactcactat caaagacgac aagctctacc agtatccagt cgctgctatt
    28741 aaggaccttc gtgcttctga agaagccttc tcaaaccgtt cccaaaccaa gaacacttac
    28801 gaacttgaac tcaacttgga agctaatagc cagagcgaga ttgtcttact tgctgataaa
    28861 gaaggtaagg gactttcaat caactttgac cttgtaaacg gtcaagtgac agtggatcgt
    28921 agccaggctg gagaacagta tgcccaagaa tttgggacaa ctcgttcttg ccctatcgag
    28981 aatcaggcta ctactgctac aatcttcatc gataactctg tctttgaaat tttcatcaat
    29041 aaaggagaaa aagtattttc tggtcgtgtc ttcccacatg cggaccaaaa tggtatcctg
    29101 atcaaatctg gaaacccaac tggaacttac tatgaattag attatggtcg caaaactaac
    29161 tgatgtcgcc aaacttgcag gcgtcagtcc tactaccgtt tctcgggtta tcaataaaaa
    29221 agggtatcta tctgagaaaa ccatccaaaa agtcaatgaa gccatgagag aattaagcta
    29281 taaacccaac aacctggctc gtagtctgca aggaaaatca gctaagttaa tcggcttgat
    29341 tttccccaat atttccaatg ttttctatgc agaattgatt gataaattgg aacaccaact
    29401 cttcaaaaat ggttacaaga ccatcatctg caacagtgaa catgattctg agaaggaacg
    29461 cgaatacatc gaaatgttgg aagccaatca ggtagacggc atcatttctg gtagtcacaa
    29521 cctaggaatc gaagactaca atcgtgtgac agcgccgatt atttcctttg accgaaacct
    29581 atcgccagac atccctgttg tctcctctga caactatgct ggtggggttc ttgctgccca
    29641 aaccttggtc aagacaggtg cccagtctat catcatgatt acagggaatg acaattccaa
    29701 ttcgccaacc ggactgcgcc acgctggttt tgcatccgta ctcccaaaag ctcctattat
    29761 caatgtttcc agtgactttt ctcccgtcag aaaagaaatg gaaatcaaga atatcttgac
    29821 ccgggaaaaa ccagatgcca tttttgcttc ggatgatttg acagctattc tgatcattaa
    29881 aatcgctcaa gaattgggca tttctgtccc aaaagagctc aaggttatcg gctatgatgg
    29941 gacctacttt atcgaaaatt actaccctca attggctact atcaagcaac ctttggaaga
    30001 gattgcttgt ctcactattg atcttctctt gcaaaagatt gaaggcaagg aagtcgccac
    30061 aactggttac ttcttaccag ttacactatt accaggaaaa agtatttaaa cacaagaaaa
    30121 ctcagaccga ttcgtctgag tttttatgat cttaaatttt cgagatagcg ctgggctgtc
    30181 tctaggttaa aggttttatc tgagatgagg cgctctacta ggggagcaac ttcagattca
    30241 ctagccccag ctaggagagc tagggatttg gcctgtagtt tcatgtggcc ttgctggatg
    30301 cccgtactta ccaaggcttt gagggctgca aaattttggg caagaccgat ggacacgata
    30361 atctgggcta attctctggc agaaggattt cctagtagat catgactgag agctacacgt
    30421 gggttgaggc cgatagagcc acccttagtc gctacaggca tgggcagggt catctcaccg
    30481 accaattctt ctctttcaag gtccagcgtc cagcaactaa gaccttgata gcgtccatct
    30541 cgactggcaa aggcatgggc cccagcttcg atggcacgcc agtcattacc agtggcaatc
    30601 aaaatcgcat caataccatt aaaaattcct ttattatgag tagcagctcg gtaaggatca
    30661 gcctgcgcaa actgactagc caacgcaatt ttctccgcaa tctctcgtcc ttgatccttt
    30721 tggcggctca agtagcgaaa ggcgatgcga cagcttgcag tcaccagaga atcggtcgcg
    30781 tagttggaca ggattcccat gagactctgt ccctgactga gttcttctaa gactggtttc
    30841 aaggcttcca gcatggtgtt gagcatattg gcacccatgg cttcctgggt atcgacatga
    30901 atataaacaa cgagaaagtc tggttcgcct tttatctgct cgacatgcag atcacgcgcc
    30961 ccacctccac gtttaacgat agaaggatag gcttgattgg caagctccaa gagctccgct
    31021 ttcttgctgg caatcttctc ttgcgctagt ttaggattag caacttgata aagggctacc
    31081 tgcccaatca tctgtcgctg atggacttgt gcagtaaaac cacctgcacg cttgatgatt
    31141 ttgctggcat agctggccgc cgcaaccaca gagggttctt ctgtcacata gggaacggtg
    31201 tattcctgac cgttgacaag tacctccgga accagtgaat aaggcagaga aaaagttccc
    31261 actacattct cactcagctg gtctgccaca gtcacgctca tctgttcatc cttctccaga
    31321 ctagcttgtc tctcaggact aaggagcgcc tgagctttta acagctcgag gcgctcttgg
    31381 tatgattttt tagaaaatcc attccaactt atcttcatta tttttcaacc ttgctataac
    31441 ggcgttggtg gtcgagaatt tcaaccaagg caaaatcttg attttcatag ccagcaaact
    31501 gggcagagtt tgtttcatcc aagtttactt cctcaaaaaa gaccttttca tagtctgcaa
    31561 cggataagac agttcgttgg ttgagcttgt tcaagcggtc tttatccaaa taagcttcat
    31621 atccttcaac caattcacca ctgaagaact cagccacagc tccacttccg taactataaa
    31681 gggcgatttt atccccagct ttcaagctat ctgtattttc caagagagac aaaagtccaa
    31741 ggaaaagtga acctgtgtag atattcccca ccttttgact gtagagaata gactggtcaa
    31801 aatgcttttg taagaggtct tttttctctt gaggcaggct cttatccatg atttttttca
    31861 agccttttag cgctaattta ggataaggca agtggaaaca aacagccgca aaatcatcca
    31921 aagtaagctg gtagcgtttt tgatattcaa gccaagtcgt tttcaaacta tccaagtatt
    31981 gttgggtaga atagacacca tttacataag gagttgtcga gtaatttggt cgccagaaat
    32041 ccatgatgtc acgggtctga gctacattgt cattattaaa ggccatcatg cgtggatttt
    32101 gtgtaatcaa catagccaca cttccggcac cctgagtggg ttctcccgga gtttcaatac
    32161 cgtatttggc aatatcactt gcaatgacca agaccttgga ctccggagaa ttttccacat
    32221 gcaatttggc ataatggagg gcagcagtcg ccccatagca ggcttcttta atctcgaaac
    32281 tacgagcaaa gggctggatg cccagcaagc catgcacaaa gacggccgca gccttactct
    32341 ggtcaattcc tgactcggtc gccacaatga ccatgtcaac ttcttgtctt tcttgctcag
    32401 ttaaaataga gtcactagca ctggccgcca aggtcacgat gtcctcagtt aggggcgcaa
    32461 tactcaattc cttgagtaag agtcctttac ttaatttttc agggtcaatt cccctcgctt
    32521 ctgctaagtc ttgtaatttc aagacatatt gactggtcgc aaaaccaatc ttatcaatac
    32581 cgattgtcat atttacctct gttttatcat tcatgtaaaa aatcgttcta tactatttta
    32641 tcacaaatgg cagtaaaaga gagaaaaaag acttgattca ccaaatcaag cctcttattg
    32701 gtcatcattt taaagaatga ttagttgcta gagagttcac cgatataagt agctttataa
    32761 gctccattca cagttatcag ctcctggagg atcaaatttc ctgagtaagt ccttcccatc
    32821 tcatctacaa atttttgata aaactgactg gtcggaattt ctctgacatc cttatcaaat
    32881 gtcttatcaa gtgttttact aaccttctca gcaatcaatt gatgctcttg ccatccactt
    32941 tgaaactctg agcccgaact agaaaccatg actgggataa acaacaaggt cagtagattt
    33001 acagacaata aggaaagtag tagacttcct gcaaaactag aatcctagtt catgattgat
    33061 aat
//
LOCUS       DAVBOG010000023        32119 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.023, whole genome shotgun sequence.
ACCESSION   DAVBOG010000023 DAVBOG010000000
VERSION     DAVBOG010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 32119)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32119)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32119
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.023"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(181..1359)
                     /locus_tag="VQ865_001130"
     CDS             complement(181..1359)
                     /locus_tag="VQ865_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family transcriptional regulator"
                     /protein_id="HET3135474.1"
                     /translation="MTLSKKQLQLRAKILETVYTLGPISRIEIATKTGITPATTSSIT
                     NDLIKENILLELGEDEHDTSVGRKKILLDIQAKRFYYIGCELSEKHFTFALGDNLGNI
                     LKEEKEIVTKQLIQEKGNQLINQTLKQFLNNCSDYEIEAIGIALPGRYLDDYKITTNN
                     PLWQHIDLEMIQSHFDKPLFFSNNVNCMAIGKRLFSRQQNDPNFAYFHFARGMHCSYI
                     YDGNIYGKGNLMIGEIGHTVVSSEGEECSCGRKGCLQTFAGESWLIKKSKILYHQSPY
                     SLLPSLVKNADDIDIQVILTAYQLGDTGIITLIHQALLYLSQTILNISMMIDSQKIYL
                     HSPLLTNQHIIQKLYSEMNYKPKLLYNRLPEVIIEPYNDFTAAHSAIALCLYHTILHS
                     "
     gene            1639..2901
                     /locus_tag="VQ865_001131"
     CDS             1639..2901
                     /locus_tag="VQ865_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3135475.1"
                     /translation="MEKLLQEKLLPVAARLGNNKALVSIRDGITLTIPLLLIGSLLMV
                     IASFPIPGWEKYLGDIGVADYLWKGVDSSFGLLGLVASFGIAYFMARQYKVDGIPAGI
                     VSLSSFITVTPFIRGEAGAGMPTAFMASKGLFVAMILGLINGYIYQWFINHNIQIKMP
                     DGVPPAVSKSFSAIIPGAVTIVGWLIVYATLDKLSLPNLHEIAQVALGGPLGLLGNNV
                     IGLLILIFLNSSFWSVGLHGGNVVNAVMKPLWLANLDANKVAYQTGETLPNIFTSVFM
                     DNFVFIGGGGATIGLVLALGYLAHKKKASKQLKTLAPITVIPGLFNINEPAMFGVPIV
                     LNILLLVPFILAPMFNLLVAWGAMASGLVPLTYTDSGWTMPPVISGLLATGSISGSLL
                     QIVLIVLDVLLYLPFVIAIEKRFKLLED"
     gene            2904..3800
                     /locus_tag="VQ865_001132"
     CDS             2904..3800
                     /locus_tag="VQ865_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HET3135476.1"
                     /translation="MKRLISANPSEILQMNAEELKQSILASEGRVVLSENVVTRETFV
                     GDITNSEIARAFGADMILLNCVDVFEPKIYALDSSGDDVIHRLHQLVACPIGVNLEPI
                     DPSAKMLEETQEIVAGRVASVETLNRIEELGFDFVCLTGNPGTGVSNREIIKAVQTAK
                     ENFSGLIIAGKMHGAGVNEPVAELSVAEQLLEAGADVILVPAVGTVPAFHDQELREVV
                     DLVHSKGGLVLSAIGTSQETSDTDTIKEIALRNKICGVDIQHIGDAGYGGLATVDNIY
                     ALSKAIRGVRHTVSRLARSVNR"
     gene            3815..4132
                     /locus_tag="VQ865_001133"
     CDS             3815..4132
                     /locus_tag="VQ865_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3135477.1"
                     /translation="MAKVTIMLACAAGMSTSLLVTKMQKAAEDKGLDAEIFAVPAPEA
                     EEIVATKEVNVLLLGPQVRYLLGDFQEKLKDRQIPVAVIPMTDYGMMNGSKVLDLAES
                     LLD"
     gene            4149..4465
                     /locus_tag="VQ865_001134"
                     /pseudo
     CDS             4149..4465
                     /locus_tag="VQ865_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344536.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
     gene            4475..5077
                     /locus_tag="VQ865_001135"
     CDS             4475..5077
                     /locus_tag="VQ865_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3135478.1"
                     /translation="MNTMLDKMQEKLSPIAMKVGNQKFLVALRDSFVGTMPVIMTGSI
                     ALLLNAFLVDLPQQFHLESITKTFQWLVDINNLVFKGSIPIVSLLFIYCLGVNIAKIY
                     KVDTVSAGLVSLASFVISIGSTVTKSFPLANVGDVKLDQILQGIDNLAFDGKNLMVTI
                     GNVIPGNHINARGRKGGISSSCWGSVVVTSSERLLETSLR"
     gene            4983..5609
                     /locus_tag="VQ865_001136"
                     /pseudo
     CDS             4983..5609
                     /locus_tag="VQ865_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782422.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
     gene            5624..6394
                     /locus_tag="VQ865_001137"
     CDS             5624..6394
                     /locus_tag="VQ865_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HET3135479.1"
                     /translation="MVEIIYFLIIIIASGLGSISGMGGGIIIKPLMDSFGYHSVSDIA
                     FYSSFSVFIMAIISTIKRFSQSKEIKWRLIFTVSFSSVLGGFLGHLIFQVLLSQLSVR
                     LVSIVQMILLFVMLLVSFVLTDFKKTYQFDKIGFYMICGLLLGLISSFLGIGGGPLNV
                     SLLMVFFSISIKEATMYSLAIIFFSQLSHLATIVVVTGLNQYHLAPVPVIFLASICGG
                     VLGTVVSKVLPENWVRYCFKGMLFFVMGMTLYNLFHIL"
     gene            complement(6672..6959)
                     /locus_tag="VQ865_001138"
     CDS             complement(6672..6959)
                     /locus_tag="VQ865_001138"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3135480.1"
                     /translation="MIVSLKTKSRKAKDMAESIQGWLAQFLVNLFKSITFDCGKEFSK
                     WKDISNHHDSESFFANLGCSRQRCLNEHSNRLLRCHDLPKQTDFNEVSQEF"
     gene            7163..7435
                     /locus_tag="VQ865_001139"
                     /pseudo
     CDS             7163..7435
                     /locus_tag="VQ865_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7545..7748)
                     /locus_tag="VQ865_001140"
     CDS             complement(7545..7748)
                     /locus_tag="VQ865_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HET3135481.1"
                     /translation="MSVEEKLNQAKGSIKEGVGKAIGDEKMEKEGAAEKVVSKVKEVA
                     EDAKDAVEGAVEGVKNMLSGDDK"
     gene            complement(7779..8387)
                     /locus_tag="VQ865_001141"
     CDS             complement(7779..8387)
                     /locus_tag="VQ865_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HET3135482.1"
                     /translation="MSNEKNTNTNVEKKDATVVAHEIKGELTYEDKVIQKIIGLSLEN
                     VSGLLGIDGGFFSNLKEKIVNSDDVTSGVNVEVGKTQVAVDLNVIVEYQKNVPALYSE
                     IREIVSSEVAKMTDLEIVEINVNVVDIKTKEQHEADSVSLQDRVSDVAESTGEFTSEQ
                     FEKAKSGLGSGFSTVQEKVSEGVEAVKGAANGVVSHENTRVN"
     gene            complement(8426..8596)
                     /locus_tag="VQ865_001142"
     CDS             complement(8426..8596)
                     /locus_tag="VQ865_001142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HET3135483.1"
                     /translation="MEWLKQYRYPIIAGLIGVFLACLIVSFGFFKTIFVLILGALGVA
                     AGLYIEKNYIDK"
     gene            complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ865_001143"
     CDS             complement(8608..9174)
                     /gene="amaP"
                     /locus_tag="VQ865_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000030212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HET3135484.1"
                     /translation="MSKAKKICFIIFCILILTIFLPVLIDYHQVSDLGIHLLSWRQNS
                     VVEFYLARYVFWGTVVLSTLVLLSILVVMFYPKRYLEIQLETKNDTLKLKNSAIEGFV
                     RSLVSDHRLIKNPTVHVNLRKNKCFVHVEGKILPSDNIADRCQIIQNEITNGLKQFFG
                     IERQVKLEVAVKNYQPKPQNKKTVSRVK"
     gene            complement(9258..9422)
                     /locus_tag="VQ865_001144"
     CDS             complement(9258..9422)
                     /locus_tag="VQ865_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3135485.1"
                     /translation="MGIIANVFAGLVGAYAGQSLLGSWGPSIAGMALLPSIIGAAIVI
                     TVVSFFTGRK"
     gene            9865..11346
                     /locus_tag="VQ865_001145"
     CDS             9865..11346
                     /locus_tag="VQ865_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3135486.1"
                     /translation="MRDLLSKKSHRQLELLELLFEHKRWFHRSELAELLNCTERAVKD
                     DLSHVKSAFPDLIFHSSTNGIRIINTDDSDIEMVYHHFFKHSTHFSILEFIFFNEGCQ
                     AESICKEFYISSSSLYRIISQINKVIKRQFQFEVSLTPVQIIGNERDIRYFFAQYFSE
                     KYYFLEWPFENFSSEPLSQLLELVYKETSFPMNLSTHRMLKLLLVTNLYRIKFGHFME
                     VDKDSFNDQSLDFLMQAEGIEGVAQSFESEYNISLDEEVVCQLFVSYFQKMFFIDESL
                     FMKCVKKDSYVEKSYHLLSDFIDQISVKYQIEMENKDNLIWHLHNTAHLYRQELFTEF
                     ILFDQKGNTIRNFQNIFPKFVSDIKKELSHYLETLEVCSSSMMVNHLSYTFITHTKHL
                     VINLLQNQPKLKVLVMSNFDQYHAKFVAETLSYYCSNNFELEVWTELELSKESLEDSP
                     YDIIISNFIIPPIENKRLIYSNNINTVSLIYLLNAMMFIRLDE"
     gene            11708..12703
                     /locus_tag="VQ865_001146"
     CDS             11708..12703
                     /locus_tag="VQ865_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000230211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3135487.1"
                     /translation="MVEQRKSITMKDVALEAGVSVGTVSRVINKEKGIKEVTLRKVQR
                     AIKTLDYIPDNYARGMKKNRTETIALIIPSIWHPFFSEFAYHVEKELLKYNYKLFICN
                     ADSDSQNEIEYIEMLKQNKVDGIIGITYSDIDKYILSDLPFVSIDRHFSENVCYVTSA
                     NYKGGQTAAEELVRRDNKHLAFIGSINMYENETILRSKGFREKAKELGVDVYNFEMKE
                     PLINPEDQIRIFLQSHKEIDGIFTINDMMALRVISVMKELGKIAPDDYQIIGFDGLKT
                     SVDQSYLVSTIVQDIGMMAKESVAMILKMIKREEILEKRIVIPTYFWGDKTTKKI"
     gene            12830..14140
                     /locus_tag="VQ865_001147"
     CDS             12830..14140
                     /locus_tag="VQ865_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3135488.1"
                     /translation="MRKGTMLSVVAGLSLAILAGCSGGTNSKQASSSNDIKVWVQFSD
                     ETNEGKAWQKVVDNFNQSGKSKYKVVTEYIPRSGSGGGYEDKVNAAITTNSLPDVITL
                     DGPNTAAYAKSKVITPLDDYLKDNNMDDVLDSIKQQGTYNGKFYAFGFSESNVGVYYN
                     KKMFKEAGIAESELPTLEKPWTWDEFNTIAKKLKDHYNKPAIDFRINSNDEMLPYAYM
                     PLIWSNNGSVVNEDGTKAEGYFNSKESVEAVQFIQNLVKEGYTTVSPVEKGFETGEYP
                     MLLSGSWTIADMNTNYKDIDFGILPYPVSSKTKKLVSPSGSWQLAVTTKSDKKEAASE
                     FVKFATNTESSEIISLGNSVLPIRKSTIENIKDKVSEPMRFLMEQNSKTAHARPVVVA
                     YPQVSRAFQQAMQDISYYEENPNVQKVLDTRTKEMQTAIDQSLK"
     gene            14236..15138
                     /locus_tag="VQ865_001148"
     CDS             14236..15138
                     /locus_tag="VQ865_001148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3135489.1"
                     /translation="MSKETVVDTKRREKIKDNILGYSFLAPALILLGIFLVIPVGMVI
                     YYAFTDYYLLTPDERKFVGLENFIRLTKDPIFLKSFLNTLKFVVWIIPVQLGAALGMA
                     LIVNKKRKGNMFFKVAFFAPVVMSLVVISILWLYLLNPNSGLLNAILNKVGIASQPFL
                     TSPKQAMYAIVFVSAWQGAGYQMLLFLGGMQNIPQDVYEAAELDGFSKWAQFRYITMP
                     LLKPTALFVLLTTLISAFKLIVQPMVMTQGGPLNSTITMVYYIYQQGFTDRLVGYSSS
                     IALVFTTLIGMINLVQRRVLKEDD"
     gene            15140..15985
                     /locus_tag="VQ865_001149"
     CDS             15140..15985
                     /locus_tag="VQ865_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3135490.1"
                     /translation="MKRFKPTTILEYILLTLLAGLFLFPMVWMVVSAMKPEADVYKNL
                     TSWQAFLPSLNPADWFKPYQEVFERFSIFTYLGNSIFYAGTFAIGSIIVNALAGFAFA
                     KVNFSGKKILFGFLLALLIIPVETVLIPQFTIINSLGLVNNRLAVIIPGLASVFNIYL
                     FRNFFIAIPEEILESAKMDGASIVRIFFRIMLPMSKPAVATVGVLSFISSWNDYIWPL
                     MVLTDSSKFSMQVAITTINTTQPVYINQVMAVLTISTIPLILVYVVAQKYIVQGLGGS
                     GTGIK"
     gene            15995..17314
                     /locus_tag="VQ865_001150"
     CDS             15995..17314
                     /locus_tag="VQ865_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 32 protein"
                     /protein_id="HET3135491.1"
                     /translation="MINKTFTVEKANRFIAENKHLVNTQYKPEEHFSAEIGWINDPNG
                     FVYFRGEYHLFYQFYPYDSVWGPMHWGHAKSKDLVTWEHLPVALAPDQDYDRNGCFSG
                     SAIVKDDRLWLMYTGHIEEKTGVRQVQNMAFSDDGIHFEKISQNPVATGSDLPDELIA
                     ADFRDPKLFEKDGRYYSVVAAKHKNNVGCIVLLGSDNLVEWQFESIFLKGVEHQGFMW
                     ECPDYFELDGKDCLIMSPMRYQREGDSYHNINSSLLFTGKVDWGEKCFIPESVQEIDH
                     GQDFYAPQTLLDDQNRRILIAWMQTWGRTLPTHDQEHKWACAMTLPRILRLEDGKLRQ
                     FPVKKGQYQIQIDKDCHYHLGNDTDYLEFGYDSNVQQVYIDRSHLIQKILGEEEQDTS
                     RRYVDIEAKELEVVLDKNSIEIFVNQGEASLTATYYLTVPAELSRID"
     gene            complement(17524..17596)
                     /locus_tag="VQ865_001151"
     tRNA            complement(17524..17596)
                     /locus_tag="VQ865_001151"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(17561..17563),aa:Lys,seq:ctt)
     gene            complement(17861..19132)
                     /locus_tag="VQ865_001152"
     CDS             complement(17861..19132)
                     /locus_tag="VQ865_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001113185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HET3135492.1"
                     /translation="MPDNLALRMRPKTIDQVIGQEHLVGPGKIIRRMVEANRLSSMIL
                     YGPPGIGKTSIASAIAGTTKYAFRTFNATVDSKKRLQEISEEAKFSGGLVLLLDEIHR
                     LDKTKQDFLLPLLESGLVIMIGATTENPFFSVTPAIRSRVQIFELEPLSNQDVKEALQ
                     IALSNPERGFDFPIELDEDALDFIATSTNGDLRSAFNSLDLAVLSTPENDEGIRHITL
                     DIMENSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVDASLHYTARLIEAGDLPSLAR
                     RLTVIAYEDIGLANPEAQIHTVTALDAAQRIGFPEARILIANVVIDLALSPKSNSAYV
                     AMDKALADLKTSGHLPIPRHLRDGHYSGSKELGNAQDYLYPHNYPGNWVKQDYLPEKI
                     RNHHYFQAEDTGKYERALAQRKEAIDHLRKI"
     gene            19402..19641
                     /locus_tag="VQ865_001153"
     CDS             19402..19641
                     /locus_tag="VQ865_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135493.1"
                     /translation="MKREVISNGNDGPSQEILIFTKQIRHWILSDQVISGKRKLFFRE
                     DTPKEILDLYENIKSKLDFAYQEVHSNNGLKKYEK"
     gene            19806..19985
                     /locus_tag="VQ865_001154"
     CDS             19806..19985
                     /locus_tag="VQ865_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135494.1"
                     /translation="MNLIFEEYQFVKIGDKKYRVRSVPMIHSTPPQSVLDRDTFTIDY
                     TDDELLDKEAVFTTH"
     gene            20122..20300
                     /locus_tag="VQ865_001155"
                     /pseudo
     CDS             20122..20300
                     /locus_tag="VQ865_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397531.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            20337..20789
                     /locus_tag="VQ865_001156"
     CDS             20337..20789
                     /locus_tag="VQ865_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HET3135495.1"
                     /translation="MLVTYPALFYYDDTDGTEATYFVHFPDFEYSATQGEGISEALAM
                     GSEWLGITVADLIESDGELPQPSDINSLSLIDNDPFKDDEDFVSTYDLDKSFISMVSV
                     DVSEYLGSQEPIKKTLTIPKWADKLGREMGLNFSQTLTDAIADKKVQA"
     gene            21080..21550
                     /locus_tag="VQ865_001157"
     CDS             21080..21550
                     /locus_tag="VQ865_001157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HET3135496.1"
                     /translation="MATYGFLDVLEEELDKNFPFDFEISWDKRNHAVEVSFLLEAQNA
                     AGVEMVDEDGEVSSDDILFEEAVLFYNPAKSTVNAEDYLTVIPYLPKKGFSREFLAYF
                     ALFLKDTAEVGLDTLMDFLEDPEAEEFVMEWNQEVFEEGKVGLEEGEFYPYPRY"
     gene            21569..22657
                     /locus_tag="VQ865_001158"
     CDS             21569..22657
                     /locus_tag="VQ865_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000719715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-2 protease family protein"
                     /protein_id="HET3135497.1"
                     /translation="MKKIGTYLVYVLAVVFIMLAFACGTIAFAELGYSAVLAFTFGYA
                     FALLSMYLIFILHELGHAFCGYLTGYRLVAFGLGHFILTKKSGRFHLSRTAILKNVGA
                     QYIGLKEDESDQRIILMLLGGLMVHLGLILLAIVFGFLTRSWYFAGTWIFLNLSFFLN
                     NILPVDITDGAKIWELLQHPENTKYAYLVLRHSAQTLLAPQEYDLKDFVQAVPEDARG
                     SFADGVLGMQGEVSILEGKEEVAKQQFQALLERTTTPMMQTVAQLSLLHIALLEGDFE
                     QAEQYASIRQVKSFLSLKLSNLQVIQAWYQLKVKKDVDRTRKALKIARQKMDSSRMLR
                     DEKRYYENLLAELEKEMLEGTEDGTRNF"
     gene            22638..23066
                     /locus_tag="VQ865_001159"
     CDS             22638..23066
                     /locus_tag="VQ865_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3135498.1"
                     /translation="MELEISDFQGCKIALFCGDKLLTILRDDKDDIPCPNMWELPGGG
                     REGDESPFECARREVYEELGIHLDEDCLLWSKIYPSVIFKGKKSVFMVGQLRQEQFDN
                     IIFGDEGQGYQLMNVEEFLSSSQVVPQLQERLKDYLKVSD"
     gene            23201..24154
                     /locus_tag="VQ865_001160"
     CDS             23201..24154
                     /locus_tag="VQ865_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000970787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HET3135499.1"
                     /translation="MMETWQELKVTVKREGEELVSNLLIELGAQGVAIEDSMDYVGNV
                     DRFGEIFPEVEQQEEIVVTAYYPDTVDVTVVEADLQARISELTDFMDLGELKIGTTAL
                     AEEDWADNWKKYYEPARITHDLTIVPSWTDYEATAGEKIIKLDPGMAFGTGTHPTTKM
                     SIFALEQVLRGGETVLDVGTGSGVLSIASSLLGAKEIFAYDLDDVAVRVAQENIELNP
                     GMENIHVAAGDLLKGVEIEADVIVANILADILIHLTEDAYRLVKDEGYLIMSGIIKDK
                     WDMVRELAESAGFFLETHMVQGEWNACVFKKTKDISGVIGG"
     gene            24156..24899
                     /locus_tag="VQ865_001161"
     CDS             24156..24899
                     /locus_tag="VQ865_001161"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HET3135500.1"
                     /translation="MQQYFVKGSAISPVTIENKETSKHMFQVMRLKEEDEVTLVFDDG
                     IKRLARVLDMENRQFELVQELNDNVELPVQVTIASGFPKGDKLEFIAQKVTELGASQI
                     WAFPADWSVAKWDGKKLGKKVEKLEKIALGAAEQSKRNIVPSIKLFEKKADFLTQLDQ
                     FDSIIVAYEESGKEGEAAALLQAVTGLETGAKLLFIFGPEGGLSPAEIESFEAKGAVL
                     VGLGPRILRAETAPLYALSALSVLVELEK"
     gene            24910..26706
                     /gene="pepF"
                     /locus_tag="VQ865_001162"
     CDS             24910..26706
                     /gene="pepF"
                     /locus_tag="VQ865_001162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3135501.1"
                     /translation="MEQKHRSEFPEKELWDLTALYQDREDFLRAIEKAREDINQFSRD
                     YKGNLHTFEDFEKAFAELEQIYIQMSHIGNYAFMPQTTDYSNDEFANIAQAGMEFETA
                     ASVALTFFDDALVAADEEVLDRLGKLPHLTAAIRQAKIKKAHYLGADVEKALTNLGEV
                     FYSPQDIYTKMRAGDFEMADFEAHGKTYKNSFVTYENFYQNHEDAEVREKSFRSFSEG
                     LRKHQNTAAAAYLAQVKSEKLLADMKGYDSVFDYLLAEQEVDRVMFDRQIDLIMKDFA
                     PVAQRYLKHVAKVNGLEKMTFADWKLDLDSALNPEVTIDDAYDLVMKSVEPLGQEYCQ
                     EVARYQEERWVDFAANSGKDSGGYAADPYRVHPYVLMSWTGRLSDVYTLIHEIGHSGQ
                     FIFSDNHQSYFNAHMSTYYVEAPSTFNELLLSDYLENQSNDPRQKRFALAHRLTDTYF
                     HNFITHLLEAAFQRKVYTLIEEGETFGASKLNSIMKEVLTDFWGDAIEIDDDAALTWM
                     RQAHYYMGLYSYTYSAGLVISTAGYLHLKNSETGAEDWLNLLKSGGSKTPLESAMIIG
                     ADISTDKPLRDTIQFLSDTVDQIIAYSAELGE"
     gene            complement(26766..27443)
                     /locus_tag="VQ865_001163"
     CDS             complement(26766..27443)
                     /locus_tag="VQ865_001163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000433071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HET3135502.1"
                     /translation="MKPDIFIITKLLSDPSRMHILDILMDGKAHTVNEIASFTKIKQH
                     TVSYHLKLLTEAQVTTLQTYGRFHYYSLKSAAIAEMLEFLSFYSPQRDVKSYKQHIHK
                     KELKVARTCYDHIAGELGISITNYLLQENLLSESEKDFQLTEAGKSYFQRKLHIDTDE
                     LKKKKRKFCPKCLDWSERKNHVGGALGNALLEFFSEKQLVIPAQTPRSLTITEKGKEF
                     LEKEWGI"
     gene            27690..28460
                     /locus_tag="VQ865_001164"
     CDS             27690..28460
                     /locus_tag="VQ865_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000966490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135503.1"
                     /translation="MLYLWGKERVKKLSVKNLKKQYGSYEAVKGISFELGDGECLGIL
                     GINGAGKTSTLKMIYSLTSISSGEIDILGQNIETNRRKSKSCLGIVGQEDMLDMTLNV
                     YDNLFAHGLCYGISSVELRKRIDSLLDFVQLSKHAQKMVNQLSGGMRRRLVLARALIN
                     RPDIIILDEPTVGLDIQSRNIIWDKLLELKELGVSIIITSHYMNEIEYLTDRVLMLHQ
                     GTIKEEGTVEDLLIKYDADNLETLFWGLTGTEKEDLHV"
     gene            28453..29217
                     /locus_tag="VQ865_001165"
     CDS             28453..29217
                     /locus_tag="VQ865_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135504.1"
                     /translation="MFKLSFHSIGHVVVRNYMSFRNLFKISIVPNLIDPLFYLLAMGF
                     GVGAYLTHVNGMLYRDFVITGLIAATAMSAATAETTVNAFIQYKIEKTYDAMLMTPIN
                     TNDIVVGQAIWAGIRAVIFGGIFWLISMLITAHFHVLMLLIPLILFIVGYLFGVLGLI
                     FTYLAPSREFLNYYNVLVIRPLYMFSDTFFPITSLPPILGDLTWFSPLYHATRMIRII
                     WGGEVTGLYLHLIWLIALALLITVLPMYMLHRRYYR"
     gene            29641..30432
                     /locus_tag="VQ865_001166"
     CDS             29641..30432
                     /locus_tag="VQ865_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2785 domain-containing protein"
                     /protein_id="HET3135505.1"
                     /translation="MYQDLLRKIAEEKPNYNQEEIQWLLDHLGDPSPEIRDDLVFTSF
                     ARGIQEELFTQEQFHFIAEVVLADGGLDKEIDKVGLSTLERSFRALVYANLLSVDANQ
                     QSVFYQGLQSEIRNVLLNQGLHYLSKEKDTTGFSSQYGWVHAFAHGADLLKEVVCHPD
                     FPKNRVHEVFDILGQLFKRMSIRFTDDEDWRLARVIYEPILQGKLAQEQVASWIKTVD
                     FPIEEREDFYKFSNFRTCLLEVYVQLDQRNSLQDELKEAIQSFQY"
     gene            30543..31211
                     /locus_tag="VQ865_001167"
     CDS             30543..31211
                     /locus_tag="VQ865_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin"
                     /protein_id="HET3135506.1"
                     /translation="MKKFVAELIGTFMLVFVGTGAVVFGNGLDGLGHLGIAFAFGLAI
                     VVAAYSIGTVSGAHLNPAVSIAMFVNKRLSSSELVNYILGQVVGAFIASGAVFFLLGN
                     SGMSTASLGENALANGVTVFGGFLFEVIATFLFVLVIMTVTSESKGNGAIAGLVIGLS
                     LMAMILVGLKITGLSVNPARSLAPAVLVGGAALQQVWIFILAPIAGGVLAALVAKNFL
                     GTEE"
     gene            complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ865_001168"
     CDS             complement(31465..31998)
                     /gene="queF"
                     /locus_tag="VQ865_001168"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HET3135507.1"
                     /translation="MKRQSALVVFSGGQDSTTCLFWAMQHYETVEAVTFAYGQRHHLE
                     IQITREIAKEQGIRHHILDMSLLGQITAQPDFATIHISYIPDKLCVESKSLKLYLFSY
                     RNHGDFHENCINTIGKDLVNLLDPRYLEVWGKFTPRGGISIDPYYNYGKQGTKYEGLA
                     EQRLFQHDLYPEKIDNR"
BASE COUNT         9733 a         5260 c         6723 g        10403 t
ORIGIN      
        1 gatcgattcg tcctgttatt atttcatttc actatacatt atgaaaaagg ggagatagga
       61 gtataatccc aaatataaag aaagcgaaca aaacagaatt ctgattttca gaaaacaggt
      121 ttattcgctt tttatgatat actccctctt tttagcctat ttattaaatg taatagaaaa
      181 ttaagaatgt agaattgtat gatacaaaca aagtgcaata gctgagtgtg cggctgtaaa
      241 atcattgtaa ggttcaataa tgacttcagg taggcgatta tagagcagtt tgggtttgta
      301 gttcatttca ctatatagtt tttggatgat gtgttgattt gttagtaaag gactatgtag
      361 gtagattttt tgagagtcaa tcatcatact gatatttaaa atggtttgac taagatagag
      421 taaggcttga tggataagtg tgattattcc agtgtcacct aattgataag cggttaaaat
      481 aacttggata tcaatatcat cggcattttt gactaaacta ggaagtagag aatagggaga
      541 ttgatgatat agaatttttg attttttgat taaccaagat tctccagcaa aagtttgtaa
      601 gcatcccttg cgcccgcagc tacattcttc tccctcagat gaaacaactg tatgccctat
      661 ttctccaatc attagatttc ctttcccata aatgtttccg tcgtagatat aagaacagtg
      721 catacctcta gcaaaatgaa aataagcaaa attagggtca ttctgttggc gactaaatag
      781 gcgtttacct atagccatac agttaacatt gttagagaaa aacaaaggct tatcaaagtg
      841 ggattgaatc atttctaagt cgatatgttg ccataaagga ttgtttgttg ttattttata
      901 atcatctaaa tagcgaccag gtagcgcgat tccaattgct tctatttcat aatcagagca
      961 gttatttaag aattgcttta gtgtctggtt aatgagttga tttccctttt cttggattaa
     1021 ctgtttagta acaatttctt tctcttcctt taagatattt cctagattat ctcctaaagc
     1081 aaaagtgaaa tgtttttcag atagttcaca accaatgtag taaaatcgtt tagcttgaat
     1141 gtctagcagg attttttttc tccctacgct tgtatcgtgt tcgtcttcac caagttctaa
     1201 gagaatattt tctttaatca gatcatttgt gatactgcta gttgttgcag gtgttattcc
     1261 tgttttagta gcgatttcaa ttcgtgaaat gggacctaat gtgtaaactg tttccagtat
     1321 tttagctctt agttgtaatt gtttcttaga taaggtcata ttagttttct tcctagttgt
     1381 cagattctta aaatcctatg attttttgct atggataaat gtagatgtta atctttttaa
     1441 gcttttcatt acttactggt ctctttttat tatatattga taataaaaaa taatcaaatg
     1501 tttacacaaa tccttgacaa ggctttctta tagttgtaaa atataaataa caaaagataa
     1561 tcaaataaca acttgacgtc aaaaaataaa gataattgat aacttttgat aataaaatat
     1621 atttaagagg aaaaggttat ggaaaaatta ttacaagaaa agttacttcc agtagcggct
     1681 agattgggta ataataaagc gttggtttct attcgagacg gtattactct aactatacct
     1741 ttattgttga taggttcatt actaatggtt attgcaagtt ttcctattcc aggatgggaa
     1801 aaatatctgg gtgatattgg tgttgctgac tatttatgga agggtgttga tagtagtttt
     1861 ggattacttg gtcttgtagc tagttttggt atcgcttact ttatggctag acaatacaaa
     1921 gttgatggta ttcctgctgg tattgtgtca ttatcatctt ttattacagt tacgcctttc
     1981 attagaggag aggctggagc aggaatgcct accgctttca tggcatcaaa aggtttattt
     2041 gttgctatga ttttaggatt gattaatggc tatatctacc aatggtttat aaatcataat
     2101 atacagataa aaatgccgga tggtgttcca ccagcagtat ctaaaagctt tagtgccatt
     2161 attcctggtg cagtgactat tgttggttgg ttgattgttt atgcaacttt agataaatta
     2221 agtttaccta atcttcatga aattgctcaa gtagctttgg gaggtccact tggactttta
     2281 ggaaataatg ttattggtct tcttatctta attttcctta atagtagttt ttggtctgta
     2341 ggattacacg gaggaaatgt tgttaatgca gttatgaaac cgttatggtt agctaatcta
     2401 gatgcaaata aagtagctta tcaaactgga gaaactcttc caaatatttt tactagcgta
     2461 tttatggata attttgtatt cataggtggc ggtggtgcaa ccataggttt agttcttgcg
     2521 ttaggatatt tagcacataa gaagaaagct agtaaacaac taaaaacttt ggcacctata
     2581 actgttatac ctggattatt taatataaat gaaccagcaa tgtttggcgt tcctattgtt
     2641 ttgaacattt tgttactagt tccatttatc ttagctccaa tgtttaactt actagtagcg
     2701 tggggagcaa tggcatcagg tttggttccg ctaacttata cagattcagg ttggactatg
     2761 ccacctgtta taagtggttt acttgctaca ggaagtattt ctggttcatt attacaaatt
     2821 gtattgattg ttttggatgt cttactttat ttaccatttg taatagctat tgaaaaacgg
     2881 tttaagttat tggaggattg agaatgaaac gtttaattag tgcaaatcca tctgagatat
     2941 tacagatgaa tgctgaagaa ttaaaacaaa gtattttagc aagtgaaggt agagttgttc
     3001 tatctgaaaa tgtagttact cgtgagacat ttgttgggga tataactaat tctgaaattg
     3061 ctagagcttt tggagctgat atgattttat tgaattgtgt tgatgttttt gagcctaaaa
     3121 tttatgcttt ggatagttca ggtgatgatg ttattcatcg cttacaccag cttgttgctt
     3181 gtccaattgg tgtaaatttg gaaccgattg acccatctgc aaagatgcta gaggaaacac
     3241 aggaaattgt tgcaggtcgt gttgctagtg ttgaaacatt gaatcgaata gaggagttag
     3301 gttttgactt tgtctgtttg actggaaatc ctggaacagg agttagcaat cgagaaatca
     3361 ttaaggctgt tcaaactgct aaggaaaact tttctggttt gattattgca ggtaagatgc
     3421 acggggcagg agtgaatgag cctgtggcag agctttctgt cgcagagcaa ttgttggaag
     3481 caggtgcgga tgtgatactt gttccagcag ttggaaccgt tccagccttt catgaccaag
     3541 agttgcgtga agtcgttgat ctcgttcata gtaagggtgg tcttgtattg agtgctattg
     3601 gtactagcca agaaacatct gatacagata ctattaagga aattgcactt agaaataaaa
     3661 tttgtggagt tgatattcaa catataggtg acgcaggata tgggggactg gcaacagtcg
     3721 ataatattta tgcattgagc aaggcaatta gaggagtgag acatacagta tctcgcttgg
     3781 ctaggtcagt aaataggtga taaaggagta agctatggct aaagtaacaa ttatgttagc
     3841 atgtgcagca ggtatgagta caagtctgct agtgacaaag atgcaaaagg cagcagaaga
     3901 taaggggttg gatgcagaaa tttttgcagt tccagctcct gaagcagaag aaattgtagc
     3961 aacaaaagaa gtaaatgtgt tgcttttagg cccccaagtt cgctatttac taggggactt
     4021 tcaagaaaaa ctaaaagata gacagattcc tgtggcggtt attccgatga cagattacgg
     4081 aatgatgaat ggttctaaag ttttagattt agctgaaagt ttattagact aagattgagg
     4141 agaatgttat ggatgaaagt aatttagaat ctgtaatggg gctaattatg tatggtggag
     4201 atgccaaaag taatgctatg gaggctattc aggcagcaaa aaaagggatt tctctaaagc
     4261 caatcgaaga ttagctgatg cgaatgctgc cttattacag gcgcataagg ctcaaacaga
     4321 aatgttgaca agagaggcac aggggggaaa aacatcaatt agcctcttga tggtacacgc
     4381 gcaagatcat ttaatgacga gtctgacttt tgttgacttg gcgaaagaag tggtagaagt
     4441 atacgaacga tttgaaaaaa attaggagtt tggtatgaat acaatgttgg ataaaatgca
     4501 agaaaaactt tctccaattg caatgaaagt tgggaatcag aagtttttag ttgctttacg
     4561 tgattcattt gtggggacta tgcctgttat tatgacaggt tccattgctt tgttattaaa
     4621 tgcttttcta gtggatttac cacaacaatt tcacctagaa agtattacga aaacctttca
     4681 gtggcttgtt gacatcaata atttggtatt caagggaagt ataccaattg tttccttgtt
     4741 gttcatctat tgcttgggag tgaatatcgc taagatttac aaggttgata cagtttctgc
     4801 tggtttggta tcacttgctt cgtttgtcat ttcgattgga agtacagtta caaagagttt
     4861 ccctttggca aatgtaggag atgtgaaatt agatcagatc ttacaaggaa ttgataatct
     4921 agcatttgat ggtaaaaatc tgatggtaac tattgggaat gtgattccag gaaaccatat
     4981 taatgccaga ggcagaaagg gagggatatc ctcatcctgc tggggctccg tggtggttac
     5041 aagttccgaa cgcttgctgg aaacatccct acggtgagaa tagtaatcta gtgggtttag
     5101 aagaccatcc agtagttcat gttgctttag aagatgcatt ggctttctgt aattggagcg
     5161 gaatgtcttt accgactgaa gcacagtggg aatatgctgc tagaggagga agacaatctg
     5221 aatatccttg gggagatact cttttagaag gtggatatta tcatgccaat acttggcaag
     5281 gaagatttcc ttatgaaaat actgtctcag atggatttat aggaacggct cctgtctatg
     5341 aatttttacc taatgatttt ggtctatatc aaatgattgg gaatgtttgg gaatggtgtc
     5401 gcaatccgag atatacctta ttagctagtt ttaatgaaga tgactatgag ttgccaaaat
     5461 atgggataca agatgaggag tatgctatca gaggaggttc ctttttatgt cattgttctt
     5521 attgtaatcg ataccgagta gctgctagaa atggatgtat ttctacttcc actagtagcc
     5581 atctaggttt tagatgtttg aaagaatagg atggacttaa aaagtggttg agattattta
     5641 ttttctaatc attataatag ctagtggatt gggttctata tcaggcatgg gtggtggaat
     5701 tataattaag ccacttatgg atagttttgg gtaccattcg gtcagtgata ttgcttttta
     5761 ttctagtttc tctgttttta taatggcgat tatttcaaca atcaaaagat tttcacaaag
     5821 taaagagata aaatggagat tgatttttac ggtatccttt tcttctgttt taggaggatt
     5881 tctaggtcat cttatttttc aagttttgtt atctcaatta tcagtacggc tagtatccat
     5941 tgttcaaatg attttactat ttgtgatgct acttgtatca tttgttttaa cagattttaa
     6001 aaaaacttat caatttgata agataggatt ctatatgatt tgtggtcttc tattgggctt
     6061 aatttctagt tttttaggga ttggtggtgg tccgctcaat gtatctttat tgatggtgtt
     6121 tttttctatt tcgataaaag aagcaacgat gtattctctt gcaattattt tcttttccca
     6181 gctgtctcat ttggctacaa ttgttgtggt tacaggttta aatcagtatc atttagcacc
     6241 tgttccagtt atttttcttg cttctatatg cggaggggta ttggggacgg ttgtatcaaa
     6301 agtcttacct gaaaattggg taagatactg ttttaaaggg atgttattct ttgtcatggg
     6361 aatgacttta tataatttat ttcatatttt gtaaggtcag tgtgaaaata tttaaataga
     6421 cttcctgtaa aaactggatt taacgccctc catttgtcaa attaagctag acagtcttac
     6481 caactcagaa aatatctgat gaggtatttg gtatccaaag gatttaggtg ggatgtgatt
     6541 tcttgaggct gggaaaaagt ctttaaaatt aaaaaatgca taatatcagg tgttggaaaa
     6601 actttgatac tatgcgtttt attgtgggaa tatttatttc attttctcct gaaattgagt
     6661 ttttgtccag cctaaaattc ttgactgact tcgttgaaat ctgtctgctt tggcaagtca
     6721 tgacacctta aaagtctatt tgaatgttcg ttgagacacc gctgtcttga acatcctaga
     6781 ttcgcaaaaa agctctcact atcgtgatga ttggaaatat ctttccattt tgaaaactct
     6841 tttccacagt caaacgtaat agatttaaag aggttcacta gaaattgtgc cagccaccct
     6901 tggatggatt ctgccatatc ctttgcctta cgactcttgg tcttcaaact gacaatcaat
     6961 tgactatacc tgttcgctca caaataggag agaactgttt acgaaaatct aatgaatatg
     7021 ccacaagaac attataccgc aacgtgtact atttttggtt cattttacta tagaaactat
     7081 tgaagaacct gtacgaaaat atatcatgaa aaagggtaga tagaaagcaa acagccttga
     7141 aatcaatgtt gactgcgatt atgaacctga atcagcccct caaaagggac tgtatatgaa
     7201 tgaacgttac cagtgtttaa aaactaaaga atatcaggca cttttatctt ccaagggtag
     7261 acaaattttc gctaaacgta agattgatat gaaatctgtc tttgggcaga taaaggtttg
     7321 tttgggttat aagagatgtc atctgagagg gaagcgtcaa gtgagaattg acatgggatt
     7381 cgtactcatg gccaacaacc tgctgaaata taataagaga aagaggcaaa attaaaaagc
     7441 tagagttccg caattgggaa tccctagctt tttgttttct gagaatcatc ttgactcaga
     7501 ctcttttgac taatgttact aaaaagataa agtaactttt aaccttattt atcgtcgcca
     7561 ctcaacatgt ttttaacacc ttctacagca ccttctacag cgtctttggc atcttcggcg
     7621 acttctttta ctttagaaac aactttttca gctgctcctt ctttttccat tttttcatca
     7681 ccgatggctt tcccaacacc ttctttaata gaacctttag cttgatttaa tttttcttct
     7741 actgacatga taatttctcc tgttatattt attttatctt agtttacacg agtgttttcg
     7801 tgagatacta caccatttgc tgcaccttta acagcttcta caccttcgct aactttttct
     7861 tgaacagttg agaaaccaga tccaagacca gatttagctt tttcgaattg ttctgaagtg
     7921 aattctcctg ttgattcagc aacgtcagat acgcgatctt gaaggcttac tgagtctgct
     7981 tcatgctgtt ctttagtttt gatgtcgaca acgtttacgt tgatttcaac aatttccaag
     8041 tcagtcattt tagcaacttc tgaagatacg atttctctga tttctgaata taaagctgga
     8101 acattttttt ggtactcaac aataacgttt aagtcaactg caacttgtgt tttaccaact
     8161 tctacgttaa caccacttgt tacgtcatcg ctgttaacga ttttttcttt aagatttgag
     8221 aagaaaccac catcgattcc caaaagacct gaaacgtttt ctagtgaaag accaatgatt
     8281 ttttggataa ctttatcttc gtaagtaagt tcccctttga tttcgtgagc tacaacagta
     8341 gcatctttct tttctacgtt agtgtttgtg tttttttcgt ttgacatatg aaactccttt
     8401 aattaaatta gtaattttta tttttttatt tatctatata gtttttttcg atatataatc
     8461 cagctgcaac tcccagtgct cctaaaatca atacaaatat tgttttgaag aagccaaagg
     8521 agacaatcaa acaagccaga aatacgccta tgagaccagc gataattgga tatcgatatt
     8581 gtttaagcca ttccattttt tacttcctta cttcacacga ctaacagtct ttttgttttg
     8641 aggttttggt tggtaatttt ttactgcaac ttcaagtttt acttgacgct caataccaaa
     8701 aaactgcttc aatccattag ttatttcatt ttgaattatt tggcatctgt cagcgatgtt
     8761 gtctgaagga agaattttac cttctacatg aacgaaacat ttattttttc gtaaatttac
     8821 atgaacagtt gggttcttga tcaatctatg atcactcacc aaacttctaa caaaaccttc
     8881 gattgccgaa ttctttaatt ttaatgtatc gtttttagtt tcaagttgga tttccaagta
     8941 acgtttagga taaaacatca caactaaaat ggataataaa actaaagttg atagaaccac
     9001 tgtcccccaa aagacatatc tagcaagata gaattcaact acggagttct gtctccagct
     9061 aagtagatga atacctagat cactaacttg atgataatct atcaaaacag gaaggaaaat
     9121 tgtcaagatt aaaatacaga aaataatgaa acatattttc tttgcttttg acatatacaa
     9181 tcctttcgat ttaacattta aactattttt cccgtcattg atttaaaaat agtttgctaa
     9241 ctttactggc gaaaagttta ctttctacct gtaaagaatg acactacagt aatcacaatc
     9301 gctgcaccta taatagatgg gagcaaagcc attccagcga ttgatggacc ccaactacct
     9361 aaaagagatt gtcctgcata tgccccgact aaaccagcga atacatttgc gatgattccc
     9421 atagaactac ttttttagtg attttacctg ccaagagacc aataagacct ccagcaataa
     9481 ttgatcacaa cactgcctac cctccttttt tattttaata tcaaaaaatc aatttctttg
     9541 attaatacta ttatataact ttaatataga aaagtcaatt atttcgattg ttattattat
     9601 ataattttaa aaaatcaaat tctttaattg ttgctattat ataattttta aaattaaaaa
     9661 tataatcttt agacttgaat ttgattctgt attcacgccc tcaatagacg gtaaaataag
     9721 aaaattgttt atatattgtc tccgtagtgt tattatacga aataaaagat tttaggaaaa
     9781 gtcgttatat catgctatac ctattctttg tggtataatt gcaagaggtt taatccgata
     9841 atttataaag agagaaagat attcatgaga gatttattat ctaaaaaaag tcataggcaa
     9901 ttagaattat tagaattatt atttgaacat aaacgttggt ttcatcgttc tgaactagca
     9961 gagttattaa attgtacaga acgtgcagtc aaagatgatc tatcccatgt taaatctgct
    10021 tttcctgact tgatttttca ttcttctact aatggtatac gcattattaa taccgatgat
    10081 agtgatattg aaatggttta ccatcatttc tttaaacatt caactcattt ttcgatttta
    10141 gaattcatct tctttaatga aggttgtcaa gctgagagta tttgtaaaga attttatatc
    10201 agttcatctt cgctctatcg tattattagc caaatcaata aagtgattaa aaggcaattt
    10261 caatttgaag tcagtctgac ccctgttcaa atcattggaa atgagagaga cattcgttac
    10321 ttttttgcac aatatttttc agaaaaatat tatttcctag aatggccatt tgaaaatttt
    10381 tcatcagagc cactatctca attgttagaa ttggtttata aggaaacaag ctttccaatg
    10441 aatttgtcaa cgcatagaat gctaaagttg ctcctagtta cgaacctata tagaataaag
    10501 tttggtcatt ttatggaagt agataaagat tcttttaacg accaaagttt ggatttttta
    10561 atgcaggcag aaggaataga aggtgttgct cagagttttg aatcagaata caatatctct
    10621 ttagatgaag aagttgtttg ccaattattt gtgtcttact ttcaaaaaat gtttttcata
    10681 gatgaaagtc tctttatgaa atgcgtaaaa aaggatagtt atgttgaaaa atcttaccat
    10741 ctattgagtg attttattga tcagatttca gtcaagtatc agattgaaat ggagaataag
    10801 gataatctga tttggcatct gcataatacc gcacatctgt atcgtcaaga gttgtttact
    10861 gagtttattt tatttgatca aaaagggaat acaatcagga actttcaaaa tatttttcca
    10921 aaatttgttt cagatataaa aaaagagctt tctcactatt tagagactct tgaggtttgt
    10981 tctagttcaa tgatggtaaa tcatctatct tataccttca tcactcatac caaacatttg
    11041 gtgattaatt tgctacaaaa tcagcctaaa ctaaaggttt tagttatgag taattttgat
    11101 cagtatcatg caaaattcgt tgcagagaca ctttcttatt actgtagcaa taattttgaa
    11161 ctggaagttt ggactgaatt agaattatca aaggaatctt tagaagattc accttatgat
    11221 atcattattt ctaattttat tattcctcct attgaaaata agagactcat ctattcaaat
    11281 aatataaaca cggtctcact catatacttg ttaaatgcca tgatgtttat tcgattagat
    11341 gagtaaccaa aaataacaaa aaaacgctat ttcgcgtttg aactgtacct caaaagttag
    11401 acagaaaaaa tctaattttt ggggtgtttt tgttaagaaa agaccttcaa tcatttaagc
    11461 aaaatgtaca tctagattta tagccctcta aaactcttgc tttttttgta gaagatacga
    11521 aaaaagccat aaaaccaagg cttttcctgt tttatgtaga tgtttacaca tgaaaattga
    11581 agtattttca aaagctaatt ggagtgattt tattcatgat gggataaatg atctggccaa
    11641 aaatgattga gaaatagttg cttaaaaagc atttgcatga tactatatat tgaaaggagg
    11701 tgataatatg gtagaacaaa gaaaatcaat taccatgaaa gatgttgctt tagaagcagg
    11761 agttagtgtt ggaactgttt cacgtgtaat taataaagaa aaaggcatta aagaagtaac
    11821 tttaaggaaa gttcaaaggg ctataaaaac attggactat atccctgata attatgctcg
    11881 aggtatgaaa aagaatagaa cagaaactat cgctttgatt attccgagca tatggcatcc
    11941 atttttttcg gagtttgcct atcatgttga gaaagagtta ttaaaatata attataaatt
    12001 atttatttgt aacgctgata gcgattcaca aaatgaaatc gaatatatcg aaatgttgaa
    12061 acaaaataaa gtggatggaa ttattggtat tacatattct gatattgaca aatatatttt
    12121 atctgattta ccgtttgtaa gtatagatag acatttttcg gaaaatgtat gctatgttac
    12181 ttcagcaaat tacaaaggag gacaaactgc agcagaggaa ctggttagaa gggataataa
    12241 gcaccttgct tttattggtt caattaatat gtatgagaat gagactatac tcagaagtaa
    12301 aggattcaga gaaaaagcta aggaattagg agtagatgtc tataattttg aaatgaaaga
    12361 acctttaata aatcctgaag atcagataag aatttttttg caatctcata aagaaattga
    12421 tggtatattt acaataaatg atatgatggc tctgagagtt attagtgtta tgaaagaact
    12481 ggggaaaata gcacctgatg attaccagat aattgggttt gatggtttaa aaacttctgt
    12541 cgatcaatct tatctagtgt ctacaatagt tcaagatatt ggtatgatgg caaaagaatc
    12601 tgttgcaatg atactgaaaa tgattaagcg agaagagatt ctagaaaaac gaatcgtaat
    12661 tcccacatat ttttggggag ataaaacaac aaaaaaaatt taaaaagcgc ttgacaatta
    12721 atgaaagcgc tgttataata taatcaacaa atgaaacgtt tcaaaaatag gctagaagct
    12781 tgtttaaaaa ataaataaaa aatgaaacgt ttcaaaaagg aggaaaatga tgcgtaaagg
    12841 tacaatgtta tctgttgttg cggggctatc gttagctata cttgcaggtt gtagtggagg
    12901 aactaactca aaacaagcga gttcttcaaa tgatattaaa gtctgggtac aattctctga
    12961 cgaaacaaat gaaggaaaag cttggcaaaa agttgttgat aactttaatc aatcaggaaa
    13021 aagtaagtac aaggttgtaa ctgagtatat tcctcgtagt ggtagtggtg gaggatatga
    13081 agacaaggtt aatgctgcta ttacgactaa tagtcttcca gatgttatta cccttgatgg
    13141 accaaatacg gcagcttatg caaaatctaa agtaattact ccgctagatg attatctaaa
    13201 agataataat atggatgatg ttttggacag tattaaacaa cagggaactt ataatgggaa
    13261 attctatgca tttggatttt ctgaatcgaa tgttggtgtt tattacaata aaaaaatgtt
    13321 caaagaggcc ggaattgcgg aatcagagct tccaacgcta gaaaagccat ggacatggga
    13381 cgaatttaat acgattgcta aaaaattgaa agatcattat aacaaaccag caattgattt
    13441 tcgtattaat tcaaacgatg aaatgttgcc atatgcttat atgccgttga tttggtcaaa
    13501 taatggttct gtcgtaaacg aagatggaac aaaggcagaa ggatacttca actccaaaga
    13561 gagtgtagaa gcagttcaat tcattcaaaa tcttgtaaaa gaaggctata caactgttag
    13621 tccagtcgaa aaaggttttg aaacaggaga gtatccaatg cttttgagtg gttcttggac
    13681 gattgctgac atgaatacaa actacaaaga tattgatttt ggtatccttc cttacccagt
    13741 atctagtaag acgaaaaaat tagtatcccc ttcaggtagt tggcaattag ctgtgacgac
    13801 aaaatctgat aaaaaagagg ccgcatctga atttgttaaa tttgctacaa atacagaatc
    13861 aagtgaaatt attagcttgg ggaattcggt ccttccaatt cgtaaatcta caattgaaaa
    13921 tatcaaagat aaagtatccg aaccaatgcg tttcttgatg gaacaaaatt caaaaacagc
    13981 tcatgctcgc ccagttgttg tagcatatcc tcaggtttct cgagcttttc aacaagcaat
    14041 gcaagatatt agctattatg aagaaaatcc aaatgtgcaa aaagtcttgg atactcgtac
    14101 aaaagaaatg caaactgcta ttgatcagtc actcaaataa tctgtaaaaa agaaggtgga
    14161 aggaaaatgt ttggaactac cttccccttt cttgttaata gcctagtttg atatatatga
    14221 ttaaaggaga tggatatgag taaagaaact gttgtggata caaaaagacg tgaaaaaata
    14281 aaggataaca tattaggtta tagtttttta gctccagctt taattttatt aggtatcttt
    14341 ttagtaattc cagttggaat ggtcatttat tacgctttta cagattatta tttgttgaca
    14401 ccagatgaaa gaaaatttgt tggacttgaa aattttattc gattaacaaa agatccgatt
    14461 ttcttaaaga gcttcttgaa tactttgaaa tttgttgttt ggattattcc agttcaattg
    14521 ggagcggcct taggaatggc tttgattgtc aataaaaagc gaaaaggaaa tatgtttttt
    14581 aaagtggctt tttttgctcc agttgtcatg tccttggtag ttatttctat tctttggctt
    14641 tatcttttaa atccaaatag tggcttattg aatgctattt taaataaggt aggtattgct
    14701 tctcaacctt tcttgactag tcctaaacaa gctatgtatg caattgtttt tgtttctgct
    14761 tggcagggtg caggttatca gatgctttta tttttaggag gaatgcagaa tattccacaa
    14821 gatgtctatg aagctgctga attagatgga ttctcaaaat gggctcagtt tcgttatatc
    14881 acgatgcccc tactaaaacc aacagccctg tttgtattgt taacaacttt aatttctgct
    14941 tttaagctga ttgtacaacc aatggttatg acgcaaggtg ggccattaaa ctcaacaatt
    15001 actatggtgt actatattta tcaacaaggt tttactgatc gtcttgtagg atattctagc
    15061 tcaatcgctt tagtatttac aacgttaatt ggtatgatta acttagtaca acgtcgcgtt
    15121 ctgaaggagg atgactaaga tgaaacgatt taaaccaaca acaatcttag aatatattct
    15181 gttaacttta ttggcaggac tcttcctttt tcctatggtt tggatggtag tttcagctat
    15241 gaagccagaa gcggatgttt ataaaaattt gactagttgg caagccttct taccaagttt
    15301 aaatcccgct gattggttta aaccttatca ggaagtattt gagcgcttta gtatttttac
    15361 atatctaggg aacagcattt tttatgctgg aacgtttgct attggttcta ttattgtcaa
    15421 tgcactggcc ggtttcgctt ttgcaaaagt caatttttca ggtaagaaaa ttttatttgg
    15481 tttcttactt gctttactta ttattccagt ggaaactgtg ttaattccac aatttaccat
    15541 tatcaattcc ttaggtttgg tcaataatcg tcttgcagtt attattccag gattggcgag
    15601 tgtatttaat atttacttat ttaggaattt ctttattgca attccagaag agattcttga
    15661 gtctgcaaag atggacggag caagtatcgt tagaattttc tttagaatta tgcttccaat
    15721 gtctaaacct gcagttgcta cagttggtgt tttatcattt atttcaagct ggaatgatta
    15781 tatctggcca ttgatggttt tgacagattc ttctaaattt tcaatgcagg ttgcaattac
    15841 aactattaat acaactcaac cagtttatat caatcaggta atggctgtat taactatttc
    15901 aacgattccg ttgattttgg tctatgtagt cgctcagaaa tatattgttc aaggtctggg
    15961 tggttccgga actggaataa aataggatat acttatgata aataaaacat ttacagtaga
    16021 aaaagccaat cgttttatag cagaaaataa acatctcgtt aatactcaat ataagcctga
    16081 agaacatttt tcagctgaga ttggttggat caatgatcca aatggatttg tctattttcg
    16141 tggagaatac catctctttt atcaattcta tccatatgat agtgtttggg ggcctatgca
    16201 ctggggacat gctaaaagta aggacttggt gacttgggag cacttgccag tggcacttgc
    16261 tcctgatcaa gattatgacc gaaatggttg tttctcaggc tctgccattg tcaaggatga
    16321 tcgcctctgg ctcatgtaca ctgggcatat cgaagaaaaa accggtgtcc gccaagtgca
    16381 aaatatggca ttttcagatg acgggattca ctttgaaaag atttcccaaa atccagttgc
    16441 aactggatca gacttgccag atgagttgat tgctgctgat ttccgtgatc caaaactctt
    16501 tgaaaaagat ggacgctatt actccgtagt agctgccaaa cacaagaata atgtgggctg
    16561 tatcgttcta ctagggtccg ataacctagt agaatggcag ttcgaatcca tctttttaaa
    16621 aggggtagaa caccaaggct ttatgtggga atgcccagat tacttcgagt tagatgggaa
    16681 agattgcctt attatgtcac ccatgcgtta tcagcgtgag ggagactcat atcataacat
    16741 caactcatcg cttttgttca cgggtaaggt agattgggga gaaaaatgtt ttatcccaga
    16801 atcagttcaa gaaattgatc atggccaaga cttctatgcg cctcaaacat tgttggacga
    16861 tcaaaatcgt cgtatcctga ttgcttggat gcagacatgg gggcgtaccc ttccaaccca
    16921 tgaccaagaa cacaagtggg catgtgccat gactttacct agaattctaa gattggaaga
    16981 tggcaaacta agacaattcc ctgttaaaaa aggccaatat caaatccaaa tagataaaga
    17041 ttgtcattac cacttaggaa atgatacaga ttatcttgaa tttggttatg acagtaatgt
    17101 gcagcaagtt tacattgatc gtagccatct tattcaaaaa attctaggtg aagaagaaca
    17161 ggacactagt cgacggtatg tagatattga agctaaagaa ttggaagttg ttctagataa
    17221 aaattccatc gagatttttg tcaatcaagg tgaagcaagc ttgactgcaa cttattactt
    17281 aacggtgcca gctgagctat cacgaattga ttaaaaatta agttatttct cctaaagaaa
    17341 aagttctctt tctaaaatag tggaaagagg actttttgtg ttttgggtat ataagcttag
    17401 tttatggtat ttgtaaaatt ggtgttggat tatgatttaa actagttttc taaagaattt
    17461 gaaaaaaatt ttatttaagc aaaaaaagcc ctatattata agacttttcc tgttgtattt
    17521 atatgccccc tacagggatc gaacctgtga cccacggatt aagagtccgc tgctctgcca
    17581 gctgagctaa ggaggcaaag aaaaaagctg tattggtgcc gaaacttcac ggtttgtatt
    17641 gaacccgcgc aattaagcag gtgggcaact cgctctaact gaagctgttt ccgtgtgaga
    17701 cggcctacat gctgttagaa gacttttgtt tccctaataa tacaaaaaat agtcggtcaa
    17761 cacttaagtg tgaagtcgta caccacagcg tttctatatt tatatgatac cactttttta
    17821 aaaaaaatca agaggaaagt gcaatttttt gaaaaggatt tcagattttt cgcaaatggt
    17881 cgatagcttc ctttctttga gccaaagccc gttcatattt accagtatct tctgcttgga
    17941 aatagtgatg attacgaatt ttttctggca gatagtcttg ctttacccaa tttccaggat
    18001 agttgtgtgg atagagatag tcttgggcat tccccagttc cttgcttcca ctgtagtgcc
    18061 catcacgtag gtgtcgcgga ataggcaagt gccctgatgt tttgaggtca gcaagtgcct
    18121 tatccatagc tacataggct gagttggatt ttggagaaag ggccaaatca atcacgacat
    18181 tggcaatgag aatgcgggct tcggggaaac caatcctttg tgcagcatcc agagcagtca
    18241 cggtatgaat ctgggcctca ggattggcta agccgatatc ttcataggcg ataacagtca
    18301 agcgacgagc gagactaggc agatccccag cctcaatcaa gcgggcagta tagtggagac
    18361 tggcatccac atctgagcca cgaatagact tttgcagggc agatagaaca tcatagtgac
    18421 cgtctccatc cttgtccata gtgatgtagc ttctctgaag actattttcc atgatgtcta
    18481 aggtgatgtg gcgaatgccc tcgtcattct caggggtaga tagaacagcc aagtccagtg
    18541 agttaaaggc agagcgaagg tctccgtttg tagaggttgc gatgaaatcc agcgcatcct
    18601 catctagttc tattggaaaa tcaaaaccac gttcagggtt acttagagct atctgcaggg
    18661 cctctttgac gtcttggtta gacagaggtt ccaactcgaa aatttgaaca cggctacgaa
    18721 tggcaggagt gacagagaag aaaggatttt cagtcgttgc tccaatcatg atgaccagtc
    18781 cactttccaa gagaggcaag aggaagtctt gcttggtctt atctagtcga tgaatttcgt
    18841 ctagcaatag gacgagacca ccagaaaatt tagcttcttc cgagatttct tgcagtcgct
    18901 ttttactatc aactgtcgca ttgaaagttc gaaaggcata cttggtcgtt ccagcgatgg
    18961 cagaggcaat actggttttg ccgattcccg gagggccata tagaatcatg gaggacaggc
    19021 ggttggcttc caccatgcgg cggatgattt ttccaggtcc gaccagatgc tcctgaccga
    19081 tgacctggtc gatggtttta gggcgcatgc gaagcgcgag attgtctggc atagcagtcc
    19141 tttctaacgt ggatttgagt agaatgactc atctactata tcttactatg tccattctag
    19201 cctattagtt gtgatatttc aatggttttg taataatcag ggagtgagat agaatctttt
    19261 ttactattta atttaatgag gagaggtatc agcatgagag atttgatttt ccttaaagct
    19321 caaaatagga tagttgagcc taaagaagtg gaagtgctga cttgagaaat aatattgctg
    19381 aatgtcattg tatgaactat aatgaaaaga gaggtgataa gcaatggaaa tgatggacca
    19441 agtcaggaaa ttttgatttt tacaaaacaa attcgtcatt ggattcttag tgatcaagtt
    19501 atttcaggga aaagaaaact tttcttccgg gaagatactc caaaagagat tttagatttg
    19561 tacgaaaaca ttaaatctaa acttgatttt gcttaccaag aagttcattc taataatggg
    19621 ttgaaaaaat atgaaaaata gaataattga tgtttttgaa gtagtaaatc gcctccttgt
    19681 aataactgtt gaaaatcctg atttcgaaga cttgagagtt aatcatactc aatgaaaatc
    19741 aaagagcaaa ctaggaaact agccgcaggc tgtacttgag tacggtaagg cgacgttgac
    19801 gtggtttgaa tttgattttc gaagagtatc agtttgtaaa aattggagat aaaaaatata
    19861 gagtacgcag tgttcctatg attcattcaa ctccgcctca atctgtctta gatcgagata
    19921 cttttacaat tgactataca gatgatgaat tgctcgataa agaagcagtt tttactactc
    19981 attagaaaaa taggtatgaa taaattggct tcccttagaa ccacatctag gggcttttat
    20041 gtataataga ataataagta tcactccttt acaatacgtg taacacgtgt tataatggtg
    20101 ttgtcaggag gtaaaagcgc tatgcctatg acacaaaaag agatggttaa actccttacg
    20161 gcccatggtt gataaagact agaggcggta aaggttccca tattaaaatc gagaagcaag
    20221 gggaaagacc tatcacaatc cctcatggtg agctgaataa gtacactgaa agagggataa
    20281 gaaagcaagc tgggttgtaa aattcagtcc ctgctttttg atatggaggt agtgaaatgt
    20341 tagttacgta tccagcttta ttttattatg acgacacaga cggaacagaa gcgacttatt
    20401 ttgtccattt cccagatttt gaatactcag ctacacaagg agaggggatt tctgaggctt
    20461 tggctatggg gtcggagtgg ctagggataa ctgttgcaga tttgatagag agtgatggag
    20521 agttacctca gccatcagat atcaatagct tgtctttaat tgataatgat ccttttaaag
    20581 atgatgaaga tttcgtgtca acctatgacc ttgataaatc ttttatttct atggtatctg
    20641 ttgatgtatc agaataccta ggaagtcagg aacccattaa aaagactttg accataccaa
    20701 aatgggcaga taagttggga cgagaaatgg gacttaactt ttctcagact ttgacagacg
    20761 ctattgcaga taagaaagtt caagcctaag attaagcgtg gtatcgtggt aatagtcaat
    20821 aaaaaagcac gtccacttgt gctagttact cgcctattga ttttatagat ttattagccc
    20881 tttcgagggc tttttatatt gatttttatg agaaatgaag aaatcagact tttaagaaaa
    20941 tcactgatac caagggttta aatgaggtaa tatggtataa ttaggacata aaataatttt
    21001 gtggtaagat ggtagtatct attttagcat atttccgagc aatcggggcg attaaagagt
    21061 cgcatagaaa gaggacaaaa tggcaacata cggattttta gatgttttag aggaagagtt
    21121 ggacaagaac tttccctttg actttgagat tagctgggac aaacgcaacc atgcggtaga
    21181 agtgagtttt ctattggaag cgcaaaatgc tgcaggtgtg gagatggtgg atgaagacgg
    21241 agaggtttca tcagatgaca ttctttttga ggaagcggtc cttttctaca atcctgccaa
    21301 gtcaaccgtc aatgcagaag actatttaac ggttatccct tatctaccta aaaaaggatt
    21361 ttctcgcgag tttttagctt attttgccct tttcctcaaa gatactgcgg aggttgggct
    21421 agataccctc atggactttt tggaagatcc agaagcagag gaatttgtta tggaatggaa
    21481 tcaagaagtc tttgaagaag gaaaagttgg cttggaagag ggagaatttt atccttatcc
    21541 aagatactag gagttggttg gaggtgttat gaagaaaatt gggacttatt tggtttatgt
    21601 gctagctgtt gtctttatta tgctagcttt tgcttgtgga acaatcgcat ttgcagagtt
    21661 ggggtattcc gcagttttag cctttacttt tggttatgcc ttcgctcttc taagcatgta
    21721 tttaatcttt attcttcatg agctgggtca tgctttttgt ggctacttga caggctatcg
    21781 gctggtggct tttggattag gacattttat tttgaccaaa aagtcaggca ggtttcatct
    21841 tagtagaaca gccattctga aaaatgttgg tgctcaatac attggtttaa aagaggatga
    21901 aagcgatcaa agaatcatcc tgatgctttt aggaggcttg atggttcatc tcggcttgat
    21961 attattggcg atagtgtttg gctttttgac aagaagctgg tattttgcag ggacttggat
    22021 ttttcttaat ttatctttct tcctaaataa cattttgcca gtcgacatca ccgatggagc
    22081 aaaaatttgg gaattactac aacaccctga aaataccaaa tacgcctacc tggtattgag
    22141 acattctgct caaactttgc tggctcctca agaatatgat ttgaaagact ttgttcaagc
    22201 agttcctgag gatgcacgag ggagttttgc ggatggtgta ttaggtatgc aaggtgaagt
    22261 ttccattttg gaagggaagg aagaagtagc taaacagcag tttcaagcat tacttgagag
    22321 gacaactact ccgatgatgc agacagttgc ccaactatcc ctgcttcata tcgccttgtt
    22381 ggaaggagat tttgagcaag cggagcaata tgctagtatt cgacaggtca aatcgtttct
    22441 gtctctcaaa ctgtccaatc ttcaagtgat acaagcctgg tatcaattaa aggtgaagaa
    22501 agatgtagat cgaactcgta aggctctcaa gattgctaga cagaaaatgg atagtagtcg
    22561 aatgttgagg gacgagaaac gctattatga aaacttgtta gcagagctgg aaaaggaaat
    22621 gttagaagga actgaagatg gaactagaaa tttctgattt ccaaggttgc aagattgccc
    22681 tcttttgtgg ggataagcta ctgacgattt tgcgtgatga caaggacgat atcccttgtc
    22741 ccaacatgtg ggagttgcca ggtggtggcc gtgaagggga cgaaagccct tttgaatgcg
    22801 ctcggcgtga agtttatgag gaactgggaa ttcatttaga tgaagactgt ctgctttgga
    22861 gcaagattta tcctagcgta atttttaaag gcaagaaatc ggtctttatg gttggtcagc
    22921 taagacaaga acaatttgac aatatcatct tcggagatga aggacagggc tatcagctga
    22981 tgaatgttga ggaatttctt agttccagtc aagttgtgcc tcagttgcaa gagagattaa
    23041 aagattattt aaaagtaagt gattagaaag gatggttcag ttaaatttct aaactgaacc
    23101 cgccctaaac actgtgccaa aaagataaac ttctcttaga cacaagcgtc ttcagagaat
    23161 ttcctatttt ggttttgtgt tttacgggct tggtatctta atgatggaaa catggcaaga
    23221 gttaaaagtt acagtgaagc gtgagggaga ggagttggtt tccaatctct tgattgagct
    23281 gggagcgcaa ggtgttgcga ttgaagacag tatggactat gtgggaaatg ttgaccgctt
    23341 cggcgagatt ttcccagagg tcgagcagca agaagaaatc gtagtgacag cctactaccc
    23401 tgacacggtg gatgtgacag tggttgaggc ggacttgcag gctcgcatat cagaattgac
    23461 ggattttatg gatttgggag agttaaaaat aggtacgact gccttggctg aggaagactg
    23521 ggcagataac tggaagaaat actatgagcc agctcgtatc actcatgatt tgaccatcgt
    23581 tccctcttgg acagactatg aggcgactgc gggagaaaaa attatcaagc tggatcctgg
    23641 catggctttt ggtacgggaa cccacccaac taccaagatg agcatttttg ccttggaaca
    23701 ggttcttcgt ggtggcgaaa cggtgctaga tgtgggaact ggttcagggg ttctctctat
    23761 tgccagctcg cttctggggg ctaaagaaat tttcgcctat gacctggatg atgtggcagt
    23821 tcgtgtggct caggaaaata ttgagctcaa ccctggaatg gaaaatatcc atgtagcggc
    23881 aggcgatttg cttaaaggcg tggagattga agcagatgtc atcgtggcaa acatcttggc
    23941 ggatatcctc attcatctga cagaggatgc ttatcgcttg gttaaggatg aaggttacct
    24001 gatcatgagt ggcattatca aggataagtg ggacatggtg cgcgagttgg ctgaatcagc
    24061 tggatttttc ctcgaaactc acatggttca aggggaatgg aatgcctgtg tctttaagaa
    24121 aaccaaggat atctctggtg tgattggagg ctagcatgca gcagtatttt gtaaaaggca
    24181 gtgctatctc tcctgtcact atcgagaaca aggaaaccag taagcatatg tttcaggtta
    24241 tgcgcttgaa agaagaggat gaggttacct tagtctttga tgatggcatc aagcgcttgg
    24301 cgcgcgtgct ggatatggaa aatcgtcagt ttgagttggt ccaagaatta aatgacaatg
    24361 tggaactacc agttcaagtg accatcgcat ctggatttcc caagggagac aagctggagt
    24421 tcatcgctca aaaagtaacc gaactgggtg ctagccaaat ctgggccttt cctgcagact
    24481 ggtcagttgc caagtgggat ggcaagaaat tgggtaaaaa agttgaaaaa ctagaaaaaa
    24541 ttgcccttgg agcagccgag caaagcaagc gtaatattgt accaagtatt aaacttttcg
    24601 agaaaaaagc agattttcta actcagctgg accagtttga ctctatcata gtagcctatg
    24661 aagaatcagg taaagaagga gaagccgctg cgcttctgca agcagtcact ggtcttgaaa
    24721 caggagccaa actgctcttt atctttggtc cagaaggcgg tctctcacct gcagaaatcg
    24781 aaagttttga agctaaggga gccgttttgg taggcctagg tcctcgtatt ttgcgagcag
    24841 aaacagcacc gctttacgcc ttatcagccc ttagtgtttt agtagaatta gagaaataag
    24901 aggaagaaaa tggaacaaaa acaccgttca gaatttccag agaaggaact ctgggactta
    24961 acagccctat accaagaccg tgaggatttc ttgcgtgcaa tcgagaaagc tcgcgaagac
    25021 atcaaccagt ttagccgtga ttacaagggc aatcttcaca cttttgagga tttcgagaag
    25081 gcctttgcgg aattggaaca gatctacatt cagatgagcc atattggcaa ctatgctttt
    25141 atgcctcaga cgacggacta tagcaatgac gaatttgcca atattgccca agctgggatg
    25201 gaatttgaaa cagctgccag cgtagccttg accttctttg acgatgcctt ggtggcagca
    25261 gacgaggaag tcttggaccg tttgggtaaa ttgccacatt taacagctgc cattcgtcag
    25321 gctaaaatca aaaaagccca ctacttaggg gcagatgtgg agaaggcctt gacaaatctc
    25381 ggtgaagttt tctatagtcc gcaggacatt tatactaaga tgcgagctgg ggattttgaa
    25441 atggctgact ttgaagccca tggcaagacc tataaaaaca gctttgtcac ctatgagaat
    25501 ttctaccaaa atcacgagga tgctgaggtt cgtgagaaat ccttccgttc cttctcagag
    25561 ggacttcgta agcaccaaaa tacggctgca gcagcctatc tggctcaggt caagtctgaa
    25621 aaactcttgg ctgatatgaa gggatatgac tctgtctttg actatcttct agctgaacaa
    25681 gaagtggacc gtgtcatgtt tgatcgccag attgacctca tcatgaagga ctttgcacca
    25741 gtcgctcaga gatacctcaa gcatgttgcc aaggtaaatg gtcttgaaaa gatgaccttt
    25801 gcagactgga aattggactt ggacagcgcc ctcaatcctg aagtgactat tgacgatgcc
    25861 tatgatttgg tcatgaagtc ggtagaacct ttggggcaag aatattgtca ggaagttgct
    25921 cgttaccaag aagagcgctg ggtggacttt gctgctaaca gtggcaagga ttccggtggt
    25981 tatgcagcgg acccatatcg cgtacaccct tatgtactca tgagctggac aggccgtttg
    26041 agcgatgtct ataccttgat tcatgaaatc gggcattctg gtcaattcat cttttcagac
    26101 aatcaccaaa gctatttcaa cgcccacatg tcgacctatt atgttgaagc accgtcgacc
    26161 ttcaatgaat tgctactcag tgattactta gagaaccagt ctaatgaccc acgtcaaaaa
    26221 cgcttcgctc tggctcatcg cttgacagac acctacttcc ataatttcat cacccacctc
    26281 ttggaagccg ccttccagcg taaggtgtat acattgattg aagaaggaga aaccttcgga
    26341 gcaagcaaac tcaacagcat tatgaaggaa gttttgacag atttttgggg cgatgccatt
    26401 gaaatcgacg acgatgcagc tttgacttgg atgcgccaag ctcactacta tatgggcttg
    26461 tatagttaca cttactctgc tggtcttgtc atctcgacag ctggttacct tcatcttaaa
    26521 aactcagaaa ctggagctga agactggctc aatctcctca aatcaggtgg tagcaagaca
    26581 ccacttgagt cagccatgat tatcggtgct gatatttcaa cagacaaacc actccgtgat
    26641 accatccaat tcttgtctga cacagttgac cagattatcg cctacagtgc tgagttgggg
    26701 gagtaagggg atagagaggt tgttatagaa tgggtatgga cagttatttg cttaaaagtc
    26761 catgtttaaa tcccccattc cttttcgagg aattctttgc ccttctctgt aatggtaagt
    26821 gaacgaggcg tttgtgcagg gatgaccaat tgtttttcac tgaaaaattc taaaagagca
    26881 ttgccgagag ctccgccgac atgattttta cgttcgctcc aatccaaaca tttagggcaa
    26941 aatttccgtt ttttcttttt caattcatcc gtatcaatgt gtaattttct ttggaaataa
    27001 gacttcccag cttcagtgag ttggaagtct ttttctgatt cgctgaggag attttcttgc
    27061 aagagataat tggtaatgga aatgccaagc tcaccagcaa tatggtcata gcaggtgcga
    27121 gcgaccttta attccttttt gtgaatgtgt tgtttataac ttttgacatc acgctgagga
    27181 gagtagaagc tgagaaattc cagcatttct gcaatggcag cactttttaa agaataataa
    27241 tgaaaacgtc cataggtttg tagagtggtt acctgcgctt cggtaagtaa tttgaggtga
    27301 tagctgacag tatgttgctt gattttggta aagctggcaa tttcgttaac cgtgtgagct
    27361 tttccatcca ttagaatatc taaaatgtgc atccgagaag ggtctgataa gagttttgtg
    27421 atgatgaaaa tatctggttt cataaaaatt ttctccaaat ttcatatatc gatgattttc
    27481 tatcttttat tatactataa ttaaagcaca agaaaaatag attttaaaaa tgttttacta
    27541 gagaatattt taaattttat tgtctgagtt taaatggagg taaaattaca aaagtaattg
    27601 cagcagtatc cacagttgaa ggacgttaat cttaagatta cattctcaac attttttcaa
    27661 aagtgagatg aattaacaaa gtatccaaca tgctctattt gtgggggaaa gaaagagtga
    27721 agaagttaag tgttaaaaat ctaaaaaagc aatatggttc ttatgaagct gtcaagggaa
    27781 ttagctttga attgggagac ggagagtgtt tgggtatctt gggaatcaac ggtgctggca
    27841 aaacatccac tttaaagatg atttactcac tgacctcaat ttcctcagga gagattgata
    27901 tcttggggca aaatattgaa accaatcgtc gtaagagtaa atcttgtctg ggtattgtag
    27961 ggcaggagga tatgctggac atgaccttga atgtttatga taatcttttt gctcacggtc
    28021 tatgttatgg tatctcatct gtcgaactta ggaagagaat cgattctctc ttggattttg
    28081 ttcaactgag caaacatgcg caaaagatgg tgaatcagct gtcgggtggg atgcgacgac
    28141 gtcttgtctt ggcaagagct ctcatcaatc ggcctgatat tatcatttta gatgaaccga
    28201 cagttggttt agacattcaa tcccgcaata ttatttggga taaacttttg gaattgaagg
    28261 aattaggtgt ttctatcatt attacttccc actatatgaa tgagattgaa tatttgacag
    28321 atagggtgct gatgctccac caagggacta tcaaagaaga aggaactgta gaagacttgc
    28381 tcatcaagta tgatgctgac aaccttgaga cgcttttttg ggggttgact gggacagaga
    28441 aggaggactt gcatgtttaa gttatcattt cactccatcg gacacgttgt ggtacgcaac
    28501 tacatgagtt ttagaaattt atttaaaatt tcaattgtcc ccaaccttat cgaccccctc
    28561 ttttatcttt tagcaatggg atttggagtt ggtgcttatt tgacgcatgt taacggtatg
    28621 ctctaccgtg attttgtcat tacaggttta attgctgcga ctgccatgtc tgcggccacc
    28681 gcagaaacaa cggtcaatgc ctttatccag tataagattg aaaagactta tgatgctatg
    28741 ttgatgacgc caatcaatac gaatgatatt gtggtaggtc aggctatctg ggcaggtatt
    28801 cgtgcagtga ttttcggtgg gattttttgg ctgatttcca tgcttatcac agcgcatttt
    28861 catgtcttga tgttattgat tcctctgatt ttatttatag tgggttattt gtttggtgtt
    28921 ttgggactaa tctttaccta cttggcgccg tctagggaat ttctgaatta ctacaatgtt
    28981 ttggtaatcc gtcctcttta tatgttttca gataccttct ttcccattac ttccttgccc
    29041 ccaatacttg gtgatttgac ttggttttct cccttgtatc acgctacccg catgattcgt
    29101 attatatggg gaggtgaggt gacaggtttg tatcttcatc ttatctggtt gatagccttg
    29161 gcgctcttga taacggtgct tcctatgtat atgttacatc gtagatatta tagatagtct
    29221 aattatttgt gatgttgtag tcatattcta atttatacta aacgttattc gaatttggac
    29281 aggtatggga actgtgccta tcaatattgt aatttatgga agttgaaata gtacggttca
    29341 gtttttaaat attgttagaa attgttttaa attccctaat caatttgtat agtttttatt
    29401 tcactttatt ataactagtt tttcgcaatt tttgagacag gaatgtgatt tttgtgataa
    29461 ggttctatca ttacaagttt atttgttgta atatggaata aatcatttat atatcttttc
    29521 agaaatatgc tgtttctctg aatataaatg tctttttctt tttaacttaa ttttacaaat
    29581 tggtaaggtc atttaagact gcctttttga acagttgcta gaaatgtaga ggtattgacc
    29641 atgtatcaag atttactaag aaaaatagca gaagaaaaac caaattataa ccaggaggaa
    29701 atccagtggt tgcttgatca tttgggagat ccttctccag aaattcgtga tgatcttgtt
    29761 tttacaagct ttgctagagg gattcaggaa gagctattta cacaggagca atttcatttc
    29821 attgctgagg tggtcttagc tgatggaggg ttagataaag agattgataa ggtaggcttg
    29881 tcaacacttg aacgttcttt tagggcactt gtttatgcaa atctcttgtc tgtagatgct
    29941 aaccagcaat cggtttttta tcagggatta caatcagaaa ttcgtaatgt ccttttaaat
    30001 caaggcttgc actatctttc aaaagaaaag gatacaacag gtttctcaag tcagtatggt
    30061 tgggttcacg cttttgcaca tggagccgat ttactgaaag aggtggtttg tcatccagac
    30121 tttcctaaaa acagagttca tgaagtattt gatatacttg gccaactatt taaaagaatg
    30181 tcgattcgct ttacagatga tgaggattgg cgtttagcaa gagtgatcta tgaacctatt
    30241 ttacaaggga agttagcgca agaacaagta gcttcttgga taaaaactgt tgattttccg
    30301 atagaagaaa gggaggattt ttacaaattt tccaacttca gaacctgtct gttggaagtc
    30361 tatgtccaac ttgaccagag aaatagttta caagatgagt tgaaagaagc tatccagtct
    30421 tttcaatact agagattagc taatagttct atgattttca aaaaatttcc aatcaatttt
    30481 cttgaaaccc tttcctactt ttgatagact agtatctagt ttttgaaaaa aggagaaaga
    30541 aaatgaaaaa atttgttgct gagttaatcg gtacgttcat gcttgtattc gtcgggacag
    30601 gagctgttgt ttttggaaat ggtcttgatg gccttggtca ccttggaatc gcctttgcct
    30661 ttggtttggc aatcgtggtg gcagcctact caatcggaac tgtttcaggt gctcacttga
    30721 atccggctgt ttcgattgct atgtttgtaa acaaacgttt gtcatcttca gaacttgtaa
    30781 actacatcct tggtcaggtt gttggagctt tcatcgcttc tggcgcagtc ttcttcctct
    30841 tgggtaattc aggtatgtca actgctagtc ttggtgaaaa tgccttggca aacggtgtca
    30901 ctgtctttgg tggtttcttg tttgaagtca tcgcaacttt cttgtttgtc ttagttatca
    30961 tgactgtgac ttcagaaagt aagggcaatg gcgcgattgc tggtttggta atcggtttgt
    31021 cattgatggc gatgattctt gtcggattga agattactgg actttcagta aacccagctc
    31081 gtagcttggc accagctgtc ttggtaggcg gcgcagccct tcaacaagtt tggattttca
    31141 tccttgcacc aatcgctggt ggagttcttg cagcccttgt tgcaaaaaat ttccttggaa
    31201 cagaagaata attgaaactc aaaaagcctt gctcctcatc ttgaggaaca gggctttttc
    31261 gtatgatact cttcgaaaat ctcttcaaac cacgtcagct tcaccttgtc ctaggtatgg
    31321 ttactgactt cgtcagttct atctgcaacc tcaaaacagt gttttaagct gacttcgtca
    31381 gttctatctg ccacctcaaa cactgctttg agtaacctgc ggctaacttc ctagtttgct
    31441 ctttgatttt cattgagtat gactttagcg gttgtcaatt ttctctggat aaaggtcgtg
    31501 ttggaagagg cgttgttctg ccaagccctc atacttagtt ccttgcttac cgtagttata
    31561 gtaggggtcg attgaaatgc caccgcgcgg agtgaatttt ccccagactt ctaaatagcg
    31621 agggtctagc aagttgacca agtctttccc gatggtgttg atacagtttt cgtggaaatc
    31681 tccgtgattt cggtagctaa atagatatag tttgagggat tttgactcga cacagagctt
    31741 gtcaggaatg taggaaatat gaatcgtcgc aaagtctggc tgagcagtga tttgtcccag
    31801 cagagacata tcgaggatat ggtgacgaat gccctgttcc ttagcgattt ctctagtaat
    31861 ttgaatttcg aggtgatgac gttggccgta ggcaaaggtg acagcttcga ctgtttcata
    31921 gtgttgcatg gcccagaaaa ggcaggttgt tgaatcttga ccaccactaa agacgaccaa
    31981 ggctgattga cgtttcatag tactccttcc aaaatgggaa atgttcagag cacgcaaaaa
    32041 gctcccatta gggagctaaa aaataccaaa tcgagttttt ttagcgatgg catatcccaa
    32101 acatcgtaat attctactt
//
LOCUS       DAVBOG010000024        31439 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.024, whole genome shotgun sequence.
ACCESSION   DAVBOG010000024 DAVBOG010000000
VERSION     DAVBOG010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 31439)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31439)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31439
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.024"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..108
                     /locus_tag="VQ865_001169"
     CDS             <1..108
                     /locus_tag="VQ865_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3135508.1"
                     /translation="TNIYLVENFDEIERYSGYLDGIERMLEISEKRMVA"
     gene            108..869
                     /locus_tag="VQ865_001170"
     CDS             108..869
                     /locus_tag="VQ865_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3135509.1"
                     /translation="MEIQDYTDSEFKHALARNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPHYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTVDVPKKTAQLLKNKGYEVQLALIATKPKLSYLSTLIRYEE
                     LYAINPNQARATPKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAADVLHELLFGEWSQVEKEMLRVGEKRLNELLEK"
     gene            897..2054
                     /locus_tag="VQ865_001171"
     CDS             897..2054
                     /locus_tag="VQ865_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001213952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135510.1"
                     /translation="MRGFNNKIKSVYQELTNSKEKFGSFHKTLIHLHTPVSYDYKLFS
                     NWTATKYRKITEDELYDIFFENKKIKVDKTIFFSNFDKVVFSSSKEYISFLMLAEAII
                     KNGIEIVVVTDHNTTKGIKKLQMAVSIIMKNYPIYDIHPHILHGVEISAADKLHIVCI
                     YDYEQESWVNQWLSENIISKKDGSYQHSLTIMKDFNNQKIVNYIAHFNSYDILKKGSH
                     LSGAYKRKIFSKENTRFLEFNINSKESSQQLDILYKEVGVLSLGQKVVAMLDFLLAYS
                     DYSKDFRPLIIDQPEDNLDNRYIYRHLVQQFRDVKAQRQIILATHNATIVTNSMTDQV
                     VIMESDGVNGWIESQGYVSEKYIKNHIINQLEGGKDSFKHKMSIYETALSE"
     gene            2873..3232
                     /locus_tag="VQ865_001172"
     CDS             2873..3232
                     /locus_tag="VQ865_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135511.1"
                     /translation="MSEQYRDIRKEVNLTADELKQIEKMMEVDNYRHFSPFVRDKILM
                     TDDKQLAAKEWFSLWQSQKFEQISRDVHLVLIIARENHQVTQEHVSILLTCVQELIVE
                     VNQAQPLSREFCEKYMG"
     gene            3308..3606
                     /locus_tag="VQ865_001173"
                     /pseudo
     CDS             3308..3606
                     /locus_tag="VQ865_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016480038.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
     gene            3593..5457
                     /locus_tag="VQ865_001174"
                     /pseudo
     CDS             3593..5457
                     /locus_tag="VQ865_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000261806.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
     gene            complement(5502..6354)
                     /locus_tag="VQ865_001175"
                     /pseudo
     CDS             complement(5502..6354)
                     /locus_tag="VQ865_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016182753.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Rgg/GadR/MutR family transcriptional regulator"
     gene            6436..6507
                     /locus_tag="VQ865_001176"
     CDS             6436..6507
                     /locus_tag="VQ865_001176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_128650800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHP2/SHP3 family peptide pheromone"
                     /protein_id="HET3135512.1"
                     /translation="MKKISKFFPILMLVMDIIIIVGG"
     gene            6611..7480
                     /locus_tag="VQ865_001177"
     CDS             6611..7480
                     /locus_tag="VQ865_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyisobutyrate dehydrogenase"
                     /protein_id="HET3135513.1"
                     /translation="MKHKKVLIIGYGIMTRGILKILKQSKKYNIYLYSRHLNSTINGI
                     IFIREDELPDAINQVDFIITCFSNHIETDNFINEFLLNIQSLRKTIVIDFTTSRIDCV
                     EKFKKTVEIKGGYYIEAPFTGGKLGSNSGQLSIFLHIDEGVNYNKKELMELLKLISKK
                     IYFFEKSTEPTKFKLIYNSWGAYLLYSIKLFNPLQYDFSPKSLEVANTIVCNDGWMSL
                     VCNSKLEQINDQDFDDIHFRVEYMVKDLEYANFSVFHDEVKEINYLLQQYRDCLVTDS
                     GKDYTVIGKYDNL"
     gene            7467..8189
                     /locus_tag="VQ865_001178"
     CDS             7467..8189
                     /locus_tag="VQ865_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3135514.1"
                     /translation="MITYRNDLLSKELDILISFFKKCEVGKISLVITGSLARGNPRIK
                     DGKLESDIDILVIVDSIQQLISIKKTLEGRFHFVHKISLIFCLKERINRSRYRGIINS
                     IRSVDNLLVDNLHIKNQIIEALDSPTNIVEQTRSMIQEFCYYSSKYLISKNNYLELKL
                     EKYWKEIATLNHIDKKIKHLDFERIFAVLKEHKIQILDSSEYFFQNVKTSENIYLEMR
                     DLVSLENQGLDFEHCILSLGER"
     gene            8186..8716
                     /locus_tag="VQ865_001179"
     CDS             8186..8716
                     /locus_tag="VQ865_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000586362.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135515.1"
                     /translation="MIINTLGPTATDCFYAINRIKLKVDVIVLYDSFDSIVNCFDKLK
                     GQYILLPVAFESSIKNYSWKDFNFEYHKRIEIVDSFHSFTKGMVLIENCNYKINRAII
                     QPATEILMLNYLKKKSMDLRIDFTHSKVMANKKFLEEGYRFSIVSQETIINNDDIIIC
                     ETFSPEMIWCLYRVKG"
     gene            8720..9814
                     /locus_tag="VQ865_001180"
     CDS             8720..9814
                     /locus_tag="VQ865_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135516.1"
                     /translation="MFSEIIKKYDIVTLKDSGFLRGDWFIGSALMAHDYESLKEGIYF
                     YPQETIWTRILDLEYINPYWEIYNQTYNFLLVNKQDSLAMNFLTSLLREIEVISSKTL
                     DFVVITSNEHLIRNLIDRDYYIITKEIPFFIENSKVGNYFKIFVKNGGQFIPIIDCTE
                     FKIQSKKYFEININKFYLKLLDYFLHGEIPEKFKFFGNTSNFNIESLFLEFIDSQENI
                     RVVSLLDCLIQLSSKNIEISGNYKGHTVKKILKKFALYSVITKLDITKVNHLLRNDYI
                     YFLMKEIDNITKKYPKLIQKYPRDILSDRYGITNEVYRYLIGENLHIKINHKLDEVRY
                     FTDIPFIDTSLSIEEFDKIVSKILKIKVGG"
     gene            9817..10488
                     /locus_tag="VQ865_001181"
     CDS             9817..10488
                     /locus_tag="VQ865_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000620361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135517.1"
                     /translation="MIRLPNKFKGNNITLEVKLNKAVDASVLYPDVKSLDQELYRQLQ
                     SVESFYLTFSDMYSEINENNEILYTEIIFKIPLCIGEDYFNFPVVSYVSNPYSLIRGF
                     YLGFHKELDCNYVFDDVELHFFREGICEFNFEFKNQNSIITAELPREYNYPLILFNNS
                     NLVNQYGKYTLLDIDKYKLESRKIFEFPEISIGNFLGSEAKSNRVIFSQDKFQINGIK
                     NMEVN"
     gene            10490..11518
                     /gene="galE"
                     /locus_tag="VQ865_001182"
     CDS             10490..11518
                     /gene="galE"
                     /locus_tag="VQ865_001182"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3135518.1"
                     /translation="MKSLLITGGAGYIGSHTVLDLLDNNYEVTIIDDLSNSKKKVIES
                     IKQISKKSRNLHFYKIDLKNEEKLENVFKRHNFDGVIHFAGYKAVGESVVEPLKYYEN
                     NLLSTINILKLMKKYKVFNFVFSSSATVYESTPIMPFYETNPLKASNPYGRTKQYIEV
                     LLNDLFISNSNWKIVCLRYFNPLGAHESGDLGEDPNGIPNNLVPYITQVAIGKLPYLN
                     IFGVDYSTPDGTCIRDYVHVNDLADGHRKALEYIFNTDEGLYEVINLGSGVGFSVFEI
                     LHSLESVIGSYIPYKITSRRAGDMDVSIADISKAEELLGWKPRYDIMKMCQDTWKWQQ
                     KHPNGYDD"
     gene            11542..12786
                     /locus_tag="VQ865_001183"
     CDS             11542..12786
                     /locus_tag="VQ865_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylate--amine ligase"
                     /protein_id="HET3135519.1"
                     /translation="MHIVLFRYSARVVKLKYLYNRNVVIIAPEVQRKKYEDYLAEGNN
                     LPKVIFLEDFILPNIILEIRRISQNTEVESITTLSEEDMDIVGFLNDHFVEKNTHSVS
                     NLLFKDKYFMRSFLVGVVNQPYFRLLESENDLRVFWNNCKSSAAILKPRNEAGSNGIK
                     KVYPNEKIDSVYFEKNYIIEEYIDIDNMITCDGYSIGSEIKRFYVHEYEELLFNTLSS
                     SGYYLVRTSSLYNDSEKIEYIEKALEECRKVLNVFSINSEITPFHFEWFLELSTGKIV
                     FCEVGKRFGGGDIPQLIEDSHGVDVIKEYWDILTNSQVLKKINFSKVISRPANISATF
                     ALYRKQGKVIEVPDEKELAWAKKVYIFIKPNTYYKVSENVVENSMFVQFNCKNSCEFE
                     KRLDELKHISQKFKYVITDSGE"
     gene            12836..13195
                     /locus_tag="VQ865_001184"
     CDS             12836..13195
                     /locus_tag="VQ865_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3135520.1"
                     /translation="MISRIGDIMFDFANNTFLAGLNPTSLSVVAIYQSLESMIGVLFN
                     LFGGVIADSFKRKKIIITTNILCGIACITLSFISQEKWLVYAIVITNVILAFMSAFSG
                     PSYKAFTKEIVKKDSIS"
     gene            13247..13999
                     /locus_tag="VQ865_001185"
     CDS             13247..13999
                     /locus_tag="VQ865_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3135521.1"
                     /translation="MIAIFLYKLLGIHGVLLLDGLSFLIAASLIFFITPVNEEVDTKE
                     NMTIRGIFDDLKIGFTYVYSHKQILTIIALSALVNFFLAAYNLLLPYSNQMFGSISSG
                     LYGTFLTAEAIGGFIGAILSGFINKSLSSKRLMLFLAYSGLMLMLTAPIYYMFRNVII
                     LAFTPALFSLFLSIFNIQFFSIVQRDVDNEFLGRVFGIIFTVAILFMPLGTVFFSVVL
                     NPNNTFNFFIIGVSITILSLIFSTLLKRYDRS"
     gene            14679..14900
                     /locus_tag="VQ865_001186"
     CDS             14679..14900
                     /locus_tag="VQ865_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135522.1"
                     /translation="MYRRLRDLREDHDLTQKQIAKILSFTDSAYAKIERGEHTLTADI
                     LVTLSNFYDVSTDYLLGLTDFPDKIRFRK"
     gene            15348..15650
                     /locus_tag="VQ865_001187"
                     /pseudo
     CDS             15348..15650
                     /locus_tag="VQ865_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            15806..17035
                     /locus_tag="VQ865_001188"
     CDS             15806..17035
                     /locus_tag="VQ865_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3135523.1"
                     /translation="MKISKRHLLNYSILIPYLLLSILGLIVVYSTTSAILIEEGKSAL
                     QLVRNQGIFWIVSLILIALIYKLRLDFLRNERLIILVILIEMLLLFLARFIGISVNGA
                     YGWISVAGVTIQPAEYLKIIIIWYLAHRFSKQQEEIATYDFQVLTQNQWLPRAFNDWR
                     FVLLVLIGSLGIFPDLGNATILVLVSLIMYTVSGIAYRWFSTILALVSATSVFVLTTI
                     SLIGVETFSKIPVFGYVAKRFSAFFNPFADRADAGHQLANSYFAMVNGGWFGLGLGNS
                     IEKRGYLPEAHTDFVFSIVIEEFGFVGASLILALLFFMILRIILVGIRAENPFNAMVA
                     LGVGGMMLVQVFVNIGGISGLIPSTGVTFPFLSQGGNSLLVLSVAVAFVLNIDASEKR
                     AKLYRELENQPMNLLLK"
     gene            17055..19751
                     /gene="ppc"
                     /locus_tag="VQ865_001189"
     CDS             17055..19751
                     /gene="ppc"
                     /locus_tag="VQ865_001189"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000058210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HET3135524.1"
                     /translation="MSLQKLENYSNKSVVQEEVLILTELLEDITKNMLAPETFEKIIQ
                     LKELSTQEDYQGLNRLVTSLSNDEMVYISRYFSILPLLINISEDVDLAYEINHQNNID
                     QDYLGKLSTTIKLVAEKENAVEILEHLNVVPVLTAHPTQVQRKSMLDLTNHIHSLLRK
                     YRDVKLGLINKDKWYNDLRRYIEIIMQTDMIREKKLKVTNEITNAMEYYNSSFLKAVP
                     HLTTEYKRLAQAHGLNLKQAKPITMGMWIGGDRDGNPFVTAKTLKQSALTQCEVIMNY
                     YDKKIYQLYREFSLSTSIVNVSKQVREMARQSKDNSIYREKELYRRALFDIQSKIQAT
                     KTYLIEDEEVGTRYETANDFYKDLIAIRDSLLENKGESLISGDFVELLQAVEIFGFYL
                     ASIDMRQDSSVYEACVAELLKSAGIHSRYSELSEEEKCDLLLKELEEDPRILSATHAE
                     KSELLAKELAIFKTARVLKDKLGDDVIRQTIISHATNLSDMLELAILLKEVGLVDTER
                     ARVQIVPLFETIEDLDHSEETMRKYLSLSLAKKWIDSRNNYQEIMLGYSDSNKDGGYL
                     SSCWTLYKAQQQLTAIGDEFGVKVTFFHGRGGTVGRGGGPTYEAITSQPLKSIKDRIR
                     LTEQGEVIGNKYGNKDAAYYNLEMLVSAAINRMITQKKSDTNTPNRYEAIMDQVVDRS
                     YDIYRDLVFGNEHFYDYFFESSPIKAISSFNIGSRPAARKTITEIGGLRAIPWVFSWS
                     QSRVMFPGWYGVGSSFKEFINKNPENIAILRDMYQNWPFFQSLLSNVDMVLSKSNMNI
                     AFEYAKLCEDEQVKAIYEIILNEWQVTKNVILAIEGHDELLADNPYLKASLDYRMPYF
                     NILNYIQLELIKRQRRGELSSDQERLIHITINGIATGLRNSG"
     misc_binding    19834..20051
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            20164..21168
                     /locus_tag="VQ865_001190"
     CDS             20164..21168
                     /locus_tag="VQ865_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3135525.1"
                     /translation="MKNKRLIGIIAALAVLVAGSLIYSSMNKSEAQNNKDEKKITKIG
                     VLQFVSHPSLDLIYKGIQDGLAEEGYKDDQVKIDFMNSEGDQSKVATMSKQLVANGND
                     LVVGIATPAAQGLASATKDLPVIMAAITDPIGANLVKDLKKPGGNITGVSDHNPAQQQ
                     VELIKALTPNVKTIGALYSSSEDNSKTQVEEFKAYAEKAGLTVETFAVPSTNEIASTV
                     TVMTSKVDAIWVPIDNTIASGFPTVVSSNQSSKKPIYPSATAMVEVGGLASVVIDQHD
                     LGVATGKMIVQVLKGAKPADTPVNVFSTGKSVINKKIAQELGITIPESVLKEAGQVIE
                     "
     gene            21237..22103
                     /locus_tag="VQ865_001191"
     CDS             21237..22103
                     /locus_tag="VQ865_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135526.1"
                     /translation="MIVSIISQGFVWAILGLGIFMTFRILNFPDMTTEGSFPLGGAVA
                     VTLITKGVNPFLATLVAVGAGCLAGMAAGLLYTKGKIPTLLSGILVMTSCHSIMLLIM
                     GRANLGLLGTKQIQDVLPFDSDLNQLLTGLIFVSIVIALMLFFLDTKLGQAYIATGDN
                     PDMARSFGIHTGRMELMGLVLSNGVIALAGALIAQQEGYADVSRGIGVIVVGLASLII
                     GEVIFKSLSLAERLVTIVVGSIAYQFLVWAVIALGFNTSYLRLYSALILAVCLMIPTF
                     KQTILKGAKLSK"
     gene            22100..22858
                     /locus_tag="VQ865_001192"
     CDS             22100..22858
                     /locus_tag="VQ865_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135527.1"
                     /translation="MTAIVELKNATKIVKNGFDEEKIILNDVSLEIFERDFITILGGN
                     GAGKSTLFNTIAGTLSLTSGTIRILGEDLTKFSPEKRAKYLSRVFQDPKMGTAPRMTV
                     AENLLIAKFRGEKRGLLPRRLTSYKDEFQVTIEKVGNGLEKHLNTPIEFLSGGQRQAL
                     SLLMATLKRPELLLLDEHTAALDPKTSVALMELTDEFVKKDQLTALMITHHMEDALKY
                     GNRLIVMKEGRIIQDLNQEEKAKMKISDYYQLFE"
     gene            22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ865_001193"
     CDS             22948..24708
                     /gene="dnaG"
                     /locus_tag="VQ865_001193"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HET3135528.1"
                     /translation="MVDKQVIEEIKNNANIVEVIGDVISLQKAGRNYLGLCPFHGEKT
                     PSFNVVEDKQFYHCFGCGRSGDVFKFIEEYQGVPFIEAVQILGQRVGIEVEKPLYSEQ
                     KSASPHQALYDMHEDAAKFYHAILMTTTMGEEARNYLYQRGLTDEVLKHFWIGLAPPE
                     RNYLYQRLSDQYREEDLLDSGLFYLSDANQFVDTFHNRIMFPLTNDQGKIIAFSGRIW
                     QKTDSQTSKYKNSRSTAIFNKSYELYHMDRAKKSSGKASEIYLMEGFMDVIAAYRVGI
                     ENAVASMGTALSREHVEHLKRLTKKLVLVYDGDKAGQAAILKALDEIGDMPVQIVSMP
                     DNLDPDEYLQKNGPEDLAYLLTKTRISPIEFYIHQYKPENSENLQAQIEFIEKIAPLI
                     VKEKSIAAQNSYIHILADSLASFDYAQIEQIVNESRQVQRQNRMERISRPTPITMPVT
                     KQLSAIMRAEAHLLYRMMESPLVLNDYRLREDFAFATPEFQVLYDLLGQYGNLPPEVL
                     AEQTEEVERAWYQVLAQDLPAEISPQELSEVEMTRNKALLNQDNMRIKKKVQEASHVG
                     DTDTALEELERLISQKRRME"
     gene            24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ865_001194"
     CDS             24711..25820
                     /gene="rpoD"
                     /locus_tag="VQ865_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HET3135529.1"
                     /translation="MATKQKEVTTFDVQVAEFIRNHKQKGTATDDEINASLVIPFTLD
                     ADGIEDLLQRIQDAGISITDNEGNPSARVLSNEEEPELSDEDLIGSTSAKVNDPVRMY
                     LKEIGVVPLLTNEEEKELALAVEAGDIEAKQRLAEANLRLVVSIAKRYVGRGMQFLDL
                     IQEGNMGLMKAVDKFDYSKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETINK
                     LVREQRNLLQELGQDPTPEQIAERMDMTPDKVREILKIAQEPVSLETPIGEEDDSHLG
                     DFIEDEVIENPVDYTTRIVLREQLDEILDTLTDREENVLRLRFGLDDGKMRTLEDVGK
                     VFNVTRERIRQIEAKALRKLRQPSRSKPLRDFIED"
     gene            25834..26163
                     /locus_tag="VQ865_001195"
     CDS             25834..26163
                     /locus_tag="VQ865_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3135530.1"
                     /translation="MAYTEEQIENIKTRILTALEEVIDPELGIDIVNLGLIYEIRFDG
                     DTGQTEIDMTLTTMGCPLADLLTDQIYDAMIEVPEVTDTEVKLVWYPAWTVEKMSRYA
                     RIALGIK"
     gene            26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ865_001196"
     CDS             26278..27321
                     /gene="cpoA"
                     /locus_tag="VQ865_001196"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosylglucosyldiacylglycerol synthase"
                     /protein_id="HET3135531.1"
                     /translation="MEKKKLRINMLSSSEKVAGQGVSGAYRELVRLLHRAAKDQLIVT
                     ENLPIEADVTHFHTIDFPYYLSTFQKKRSGRKIGYVHFLPATLEGSLKIPFFLKGIVK
                     RYVFSFYNRMEHLVVVNPMFIEDLVAAGIPREKVTYIPNFVNKEKWHPLPQEEVVRLR
                     TDLGLSDNQFIVVGAGQVQKRKGIDDFIRLAEELPQITFIWAGGFSFGGMTDGYEHYK
                     KIMENPPKNLIFPGIVSPERMRELYALADLFLLPSYNELFPMTILEAASCEAPIMLRD
                     LDLYKVILEGNYRATAGREEMKEAILEYQANPATLKDLKEKAKNISREYSEEHLLQIW
                     LDFYEKQAALGRK"
     gene            27337..28662
                     /locus_tag="VQ865_001197"
     CDS             27337..28662
                     /locus_tag="VQ865_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3135532.1"
                     /translation="MRIGLFTDTYFPQVSGVATSIRTLKTELEKQGHAVFIFTTTDKD
                     VNRYEDWQIIRIPSVPFFAFKDRRFAYRGFSKALEIAKQYQLDIIHTQTEFSLGLLGI
                     WIARELKIPVIHTYHTQYEDYVHYIAKGMLIRPSMVKYLVRGFLHDVDGVICPSEIVR
                     DLLSDYKVKVEKRVIPTGIELAKFERPEIKQENLKELRSKLGIQDGEKTLLSLSRISY
                     EKNIQAVLVAFADVLKEEDKVKLVVAGDGPYLNDLKEQAQNLEIQDSVIFTGMIAPSE
                     TALYYKAADFFISASTSETQGLTYLESLASGTPVIAHGNPYLNNLISDKMFGTLYYGE
                     HDLAGAISEALIATPDMNEHTLSEKLYEISAENFGKRVHEFYLDAIISNNFQKDLAKD
                     DTVSQRIFKTVLYLPQQVVAVPVKGSRRMLKASKTQLISMRDYWKDHEE"
     gene            28693..28869
                     /locus_tag="VQ865_001198"
     CDS             28693..28869
                     /locus_tag="VQ865_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3135533.1"
                     /translation="MRSGRDKKIAGVCAGVAHYLDMDPTIVQVIWGVLTCCYGAGIVA
                     YIILWIIAPVATDY"
     gene            28928..29062
                     /locus_tag="VQ865_001199"
     CDS             28928..29062
                     /locus_tag="VQ865_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HET3135534.1"
                     /translation="MAFGDNGNRKKTMFEKITLFIVIIMLVASLLGIFATAIGALSNL
                     "
     gene            29126..30436
                     /gene="obgE"
                     /locus_tag="VQ865_001200"
     CDS             29126..30436
                     /gene="obgE"
                     /locus_tag="VQ865_001200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002984148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HET3135535.1"
                     /translation="MSMFLDTAKIKVKAGNGGDGMVAFRREKYVPNGGPWGGDGGRGG
                     NVVFVVDEGLRTLMDFRYNRHFKADSGEKGMTKGMHGRGAEDLRVRVPQGTTVRDAET
                     GKVLTDLIEHGQEFIVAHGGRGGRGNIRFATPKNPAPEISENGEPGQERELQLELKIL
                     ADVGLVGFPSVGKSTLLSVITSAKPKIGAYHFTTIVPNLGMVRTQSGESFAVADLPGL
                     IEGASQGVGLGTQFLRHIERTRVILHIIDMSASEGRDPYEDYLAINKELESYNLRLME
                     RPQIIVANKMDMPESQENLEEFKKKLAENYDEFEELPAIFPISGLTKQGLATLLDATA
                     ELLDKTPEFLLYDESDMEEETYYGFDEEEKAFEISRDDDATWVLSGEKLMKLFNMTNF
                     DRDESVMKFARQLRGMGVDEALRARGAKDGDLVRIGKFEFEFVD"
     gene            30446..30604
                     /locus_tag="VQ865_001201"
     CDS             30446..30604
                     /locus_tag="VQ865_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135536.1"
                     /translation="MGDKPISFRDADGNFVSAADVWNEKKLEELFNRLNPNRALRLAR
                     TKKENPSQ"
BASE COUNT        10502 a         4775 c         6356 g         9806 t
ORIGIN      
        1 acaaatatct atttagtaga aaattttgat gaaatagaga gatatagcgg ctatttggat
       61 ggaattgaac gtatgttaga gatatctgaa aaacggatgg tagcctagtg gaaatccaag
      121 attatactga cagtgaattc aaacatgctc tagcacggaa tcttcgttca ctgacaagag
      181 gaaaaaagtc cagtaagcaa cctatagcga ttttgctcgg agggcaaagt ggtgccggta
      241 agactacaat tcatcgtatt aaacagaaag aatttcaagg aaatattgtt atcatagatg
      301 gagatagttt tcgttctcag catccacact atttagaact gcagcaagaa tatggcaaag
      361 atagtgtaga atacaccaaa gattttgcag gtaaaatggt agagtcttta gtaacagaat
      421 tgagtcattt gggatacaat cttttgatag agggaacttt acgaacagtt gatgttccaa
      481 agaaaacagc acaactcttg aaaaataagg gatatgaagt acaattagcc ttgattgcga
      541 caaagcctaa gctgtcctat ctgagcactc ttattcgata cgaagaactg tacgctatca
      601 atccaaatca agcacgcgca acaccaaaag aacatcatga tttcattgta aatcatctag
      661 ttgataatac acgacaattg gaagaactag ctatttttga aagaattcaa atttaccaac
      721 gagatagaag ttgtgtatat gattcaaaag aaaatacaac ttcagcagca gatgttcttc
      781 atgagttatt gtttggagag tggagtcagg tagaaaagga gatgttgagg gtaggggaaa
      841 agagacttaa tgaattactt gaaaaataaa caattgatat ttttaggaga gtagaaatga
      901 gagggtttaa taacaagata aagtctgttt atcaagaact aacaaattcc aaagagaaat
      961 tcggtagctt tcacaagact ttaattcatt tgcatacacc tgtttcttat gattacaagc
     1021 tattttctaa ttggactgca acgaaatata gaaaaattac tgaagatgaa ctatatgata
     1081 tattttttga aaataagaaa ataaaagttg ataagacaat tttttttagt aattttgata
     1141 aggttgtttt ttctagttca aaagaatata ttagttttct tatgttagca gaggcaatca
     1201 taaaaaatgg aatagaaata gttgtagtaa ctgatcataa tactaccaaa ggtattaaaa
     1261 agttacaaat ggcagtctca atcataatga aaaattatcc gatttatgat atacatcctc
     1321 atattttaca tggagtagaa attagtgcag cagataaatt gcatattgta tgtatatatg
     1381 attatgaaca agaatcatgg gttaatcaat ggttaagtga aaatattata agtaagaaag
     1441 atggaagtta tcaacattca ctgactataa tgaaggattt caataatcaa aaaatagtta
     1501 actatattgc tcatttcaat agttatgaca ttttgaaaaa aggttctcac ttatcaggtg
     1561 catataaacg aaaaattttt tctaaagaaa atacacgatt tttggagttt aatattaact
     1621 cgaaagaatc ttcgcaacaa cttgatattc tctataaaga agttggtgta ttaagtttgg
     1681 gacaaaaagt tgtagccatg cttgattttt tattagcata tagtgactat tctaaagact
     1741 tcagaccatt gattattgat cagcctgaag acaatctaga caatcgttat atttacaggc
     1801 atttagttca gcagtttaga gatgtgaaag ctcaacgtca aattatttta gcaacacata
     1861 atgctacaat tgtaacaaat tctatgacag atcaagttgt tattatggag tcagatggag
     1921 ttaacggatg gattgaatca cagggatatg ttagtgaaaa atatataaaa aatcatatca
     1981 tcaatcaatt agagggagga aaagattcct tcaagcataa aatgtctata tatgagacgg
     2041 ctttatcaga gtagagtcag aaaaagtagg ttagaaattt agcctacttt tttctttgtt
     2101 cgacaggcat agtgtacatc tgaggtccaa gtcctctgtg gatatttgct gcagatgaaa
     2161 ccaatagcga ctcctaagcc tgaatatcgt gatgtagggg ggataggaag gaattagcga
     2221 aatcaaggtt ctacaaacag aatcgtgact tgaagccata tatagcggat gaggaactct
     2281 aaaatccaaa taggtgtcgt aacctatata cgtaaattac gagagtaaac taggaaagat
     2341 gtacggctta ttccgtgagc gtttaggacg tagtacaacg aatcatggga gtcagctgaa
     2401 cacatagtat tgaagaaatt tctgtaatgg aaatggagcg aagaagtgaa caattaaatg
     2461 aatacctctc taattaaatt tgtcaattct aattcctggt atgaaaagac agtgacctaa
     2521 aaatgtaaac gatgggagct gatcataaat ataggacggt acatgcagtg gtgttagaga
     2581 ttagtcccta cttgatttgt gataacttcc ccaactttct tctgctatac ttttctcaac
     2641 ttttaaaaat ccaactaaga attttacctg ggagtttggg ggcgtagcca ccaagttatc
     2701 ttatggttag ctgtcaaaac tggaaggttt tggttagctg gcgatatgat tttttgggta
     2761 ttgtgaccac aatgcctgag ctcgcaaaga ccgaacaagg actttaagaa atttcccgta
     2821 tgacacacgg ggtcggggtt tacccgagaa aggatgaaag tgaggaaaag agatgtctga
     2881 acagtaccgt gacattcgaa aagaggtaaa tctaaccgca gatgagctaa aacagattga
     2941 aaaaatgatg gaggttgata attatcgtca cttttcacca ttcgtcaggg ataaaatttt
     3001 gatgactgat gacaaacagt tagctgccaa agaatggttt tccctttggc agtctcaaaa
     3061 gtttgaacag atcagtcgag atgtgcattt ggttttgatt atcgcaagag agaatcatca
     3121 agtgactcaa gagcacgtct caatcttatt gacttgtgtt caagaattaa ttgtagaagt
     3181 caatcaagct cagccactca gtcgtgaatt ctgtgaaaaa tatatgggat aggagactgc
     3241 tatggtttat cgttatcgta ctaatctaaa aaaatatttc taactgattc agaattgaat
     3301 taattaaatg atcgtattac taagagtcac tgtcaaaatt tctcagtcta cgccagaaaa
     3361 gttttgctta atcccaatat gtcatttgtc acgattaaca ctgatactta tgaacagtta
     3421 gtgtttgaat tgaggaggat tggaaataac atcaatcaaa ttgcgcgtgc gattaatcaa
     3481 agccatctga tttctcagga ccaattacaa gaattgagta aaggagtcgg agagttaatt
     3541 aaggaagtgg acaaagaatt tcaagtggag gtgaaaagac tgaaggagtt tcatggtagt
     3601 tactaaatac tttgcgacgc acggaaaaaa atatcgtagg cgtttgatta aatatatcct
     3661 caatccagat aaaacagata atctaaaatt agtatctgat tttggcatga gtaattactt
     3721 agattttcct agccatgcag aaatggtaga aatgtacaat gttaacttta ctaataacga
     3781 caagttgtac gagtccagaa atgaccgaca agaaaaacac caacaaacta ttcatgccca
     3841 tcatctcatc caatcatttt ctcctgaaga taatctgaca cctgaagaaa ttaaccgcat
     3901 tggttatgag accatgatgg aattgacagg aggtcgtttt aagtttatcg tagcaactca
     3961 cacagacaaa gatcatgttc ataatcacat cctaattaac gctattgacc gcaattcaga
     4021 taaaaagttg atatggaact atgccttgga acgaaacctc cgtatgattt cagaccgtat
     4081 ttctaaaatg gctggtgcaa aaattattga gaaacgttat tcctatcgag attataaaaa
     4141 atataaggaa tctagtcata aatttgaatt gaaacaacgt ctttattttt tgcttcagca
     4201 atctaaatcg tttgatgatt ttttagagaa agcaaagcag ttgcatgttc agattgattt
     4261 tagtcaaaag catagccgtt ttttgatgac agatagaacg atgataaaac caattcgagg
     4321 tcgccaactt agtaaacgag atttatatga tgaagacttt tttaaaacat attttgccaa
     4381 acaagagatt gaaagtcatt tagaattttt gttgaaccgt gtcaattctt tagaagagtt
     4441 aataacaaaa gcaaaagaat tgaatctaac cattgactta aaacaaaaaa atgtaacttt
     4501 tatcctggaa gaagataatc aaaagataag tttgggtcat aaaaaataag tgataagaaa
     4561 ttatatgatg tcaaattttt tcaagattat tttaaaaata aggaagtcgt tgcttcagaa
     4621 ggattagaga atttatagga acagtaccat gctttccaag aagaacgaga taaggataaa
     4681 gtatccactg aagagattga ggaagccttt gagatattta aggaaaagag agatgctgtt
     4741 cgtgaatttg aagtggaact tgcagagaac caaatagaga agctagttga tgagggaatt
     4801 tatatcaaag tgtcttttgg tattaagcag agtggtctta ttttcattcc caattatcaa
     4861 ttggatacta tggaagaaga caatcagaaa aaatataaag tctacattcg agaaacgtct
     4921 tcttactttg tctataataa agaaaacatg gataataatt gtttcatcaa gggtaggacc
     4981 ttaatcagac aattgagcaa cgatagccaa aaactcccct atagacgacc aactttaaaa
     5041 agtcttcaag agaagatttc taaaattaat cttatgattg aactatctaa cacgaacaaa
     5101 caataccaag aaatcaaaga tgagcttgta ttagaaattg cagagattga tatgcagcta
     5161 gaagaaaccc aagaaaaaat cgccacctta aacaagatgg cggaagtcct tatcaatttg
     5221 aagagtgaag atcatgagac tagaaaatta gctaagtatg attttgacca aatgaacatg
     5281 acggaatcaa taatgttaga tcgactcaat acggatattt taaaattaca acaggaactt
     5341 ggtaatgaaa ttaataaata tgaggagata gctagaagat tggatttgtt tgtgaaaatt
     5401 attaatacca ataaatttac agttctaaaa tttcacgaga atgccttact agaataatat
     5461 tatttacgac taattagtta aaagatagag aataatttca tttatttttt atttactagt
     5521 ttattaaaat ggtcagtata gtgtaatttt aacttgtatt ctcctaaaat atcgagaact
     5581 tgtatagctt gtttcattgt ttcaatacca ctacttaatt gacgtttaaa ttcatagtaa
     5641 ccggttgcat agagaaaaac tgtctgttca taaaagttta attcattctc taacaatccc
     5701 tttatctcat taattaaata agagcaatta gaaaattctt ctttatctat gctgagaatg
     5761 aaacaattta tagctagctg agtgacaatc cgcttatttg ttttatttag agatgagtaa
     5821 atataattat ttaacatttc tttagttaag taagaagtag gagttgtagt taattgttcg
     5881 tacacagtta cctaataaaa taatctcata ataaccccat ttttcaactt taaagagata
     5941 atctgctagt tgaagtaatt catcatctga tggaatgatt cttgaatcca ttgtgtgtaa
     6001 aatggatttt accattgttt tttcaaaaga atctaaagtg taatttgagg aatccgaaag
     6061 tagagattgt atattattga tgttttgtaa tgaatattgt ttacggatat actgtattaa
     6121 gttggcaaat gactcagttt ttgtatagtc ttcatcgtgt aaaataagaa actcatccaa
     6181 agtaatgtgt aatttgtcta aaatattgat cagtcggata catgatatct ctgactctcc
     6241 acgttcaaat cgggatattt gcgattttga aagatgctca tcagcaacag agcatagact
     6301 gatttgtttg cctttacgaa cttttctaag tgtgatgcca agttttgatt tcatagtttt
     6361 tcccattttc ccaacaaaaa gttaacttag ttttatttat tgtacaataa ataaaaattg
     6421 aaaggaagtc taaatatgaa gaaaatttca aaatttttcc caattttgat gctagtgatg
     6481 gacattatca ttattgttgg tggttaaatc acttaggtgt acacctaagt ctttagagta
     6541 tctaaagact atacttacta gctaaaacat atttaagtta aatcgtaaaa ttttagagag
     6601 tggtgagact ttgaaacata aaaaagtatt aattataggg tatggtataa tgactcgggg
     6661 tatattaaaa atcctgaaac agtcgaaaaa atataatata tacctatata gtaggcatct
     6721 aaattcaaca ataaatggaa taatatttat tagagaagat gaattacctg atgctataaa
     6781 tcaggttgat tttataatca cttgttttag taatcatatt gaaacggata atttcattaa
     6841 tgagttttta ttaaatatac aatcacttcg taaaaccata gtaattgatt ttacaacctc
     6901 caggattgat tgcgttgaaa aatttaaaaa aactgttgaa attaaagggg gatactatat
     6961 agaggctcct ttcacaggag gtaagttagg aagtaatagt ggtcaactat caattttttt
     7021 acatattgat gaaggtgtaa actataataa aaaggagtta atggaattat taaaattaat
     7081 ttcaaaaaaa atatactttt ttgaaaagag tacggaacca acaaaattca agttaattta
     7141 taactcgtgg ggagcgtatt tgctttactc tattaagcta ttcaaccctt tacagtatga
     7201 tttttcacca aagtctctag aggtagcgaa tacaatcgta tgtaatgatg gttggatgag
     7261 tttagtatgc aactccaaat tagaacagat caatgatcaa gattttgatg acatacactt
     7321 tagagtagaa tatatggtaa aagatttaga atatgctaat ttttcagtct ttcatgatga
     7381 agtgaaagaa ataaattatt tattacagca atatagggat tgcttagtaa ctgatagtgg
     7441 aaaagattat acggtaatag gaaagtatga taacttatag gaatgacttg ctgtctaaag
     7501 aattagatat actaatttca ttttttaaaa aatgcgaggt aggaaaaatt tcactcgtta
     7561 ttactggttc cttggcaaga ggtaatccaa gaatcaagga tgggaaatta gaatcggata
     7621 ttgatattct agttatagta gacagtattc agcaattaat tagtataaaa aagactttag
     7681 agggaaggtt tcactttgta cataaaattt ctttgatttt ttgtttgaag gaaagaataa
     7741 atcgaagtcg ttatcgtgga attattaata gtattagaag tgtagataat cttttagtag
     7801 ataatctgca tataaaaaat caaataatag aagctttaga ctcacctacc aatattgtgg
     7861 agcagactcg ctctatgatt caggaatttt gttattattc atcaaaatat ttaatttcaa
     7921 agaataatta tttggaatta aaactagaaa agtattggaa ggagattgca acattaaatc
     7981 atatcgataa aaagataaaa cacctagatt ttgaaagaat atttgctgtt ttaaaagaac
     8041 acaaaataca aattttggat tcaagtgaat attttttcca aaatgtaaaa acttctgaga
     8101 atatttattt agagatgagg gatttagtat ctttggaaaa tcaaggatta gactttgaac
     8161 attgtatttt gagcttgggg gaaagatgat aataaataca ttaggaccaa ctgcaacaga
     8221 ttgtttttat gcaataaatc gtataaaatt aaaagtagat gtgattgtac tgtatgatag
     8281 ttttgatagt atagttaatt gctttgataa attaaaaggg caatatatat tattacctgt
     8341 agctttcgag agtagtatta aaaattatag ttggaaagat ttcaactttg aatatcataa
     8401 gcggattgaa attgtggatt cttttcactc ttttactaag ggaatggttc taatcgagaa
     8461 ttgtaattat aaaattaata gggcgattat ccaacctgca actgagattt tgatgttaaa
     8521 ctatttaaag aaaaaaagta tggatctgag gatagatttt acccatagta aagttatggc
     8581 aaataaaaaa tttctggaag aaggttatcg tttttcaata gtaagccaag aaacgataat
     8641 taataatgat gatattatta tttgtgaaac tttctctcca gaaatgattt ggtgcttata
     8701 tagagtgaaa ggatagaaaa tgttttctga aattattaag aaatatgata ttgttacact
     8761 gaaagatagt ggttttttga gaggtgattg gttcataggt tcagcgttaa tggctcatga
     8821 ctatgaaagc cttaaggaag ggatatattt ctatccccag gaaacaattt ggacaagaat
     8881 cttggattta gaatatataa atccgtattg ggaaatatat aatcaaactt ataatttctt
     8941 attagttaat aaacaagatt cattagcaat gaatttttta actagtcttc taagagaaat
     9001 agaagttatt tcgtctaaaa cattagattt tgttgttatt acttcaaacg aacacctaat
     9061 taggaattta attgatagag actattatat tattacaaaa gagattccat tttttattga
     9121 aaactcaaaa gttggaaatt attttaaaat ttttgtgaaa aatggaggac agtttattcc
     9181 tataattgac tgtacggaat ttaagattca gtctaagaaa tattttgaga taaatattaa
     9241 taaattctac ctgaaacttt tggattactt tcttcatgga gagattccag aaaaatttaa
     9301 attttttgga aatacctcta atttcaatat agaaagcttg tttctagaat ttattgatag
     9361 ccaagaaaat attcgagtag tttccttgtt ggattgtctt attcaattat cctctaaaaa
     9421 tattgaaatt tcaggaaatt ataaagggca cacagtgaaa aaaatactaa aaaaattcgc
     9481 tttatactca gtaattacca aacttgatat aacgaaagta aatcatttat tgagaaatga
     9541 ttatatctac tttttaatga aggaaattga caatattact aaaaaatatc caaagttaat
     9601 tcaaaagtac cctagagata tcttgagtga taggtatgga ataacaaatg aagtatatag
     9661 atacttaatc ggagagaatt tacatataaa aattaatcat aaattagatg aggttagata
     9721 ttttacagat attccattta ttgatacttc actttctatt gaagagtttg acaaaatagt
     9781 ttctaaaata ttaaaaatta aagtgggagg gtaactatga taagattacc aaataaattt
     9841 aaaggtaata atataactct agaagttaaa ctaaataaag cagttgatgc tagtgtatta
     9901 tacccagatg ttaagtctct agatcaagaa ttgtatcgac aactacaatc agtagaatca
     9961 ttctatctta ccttttctga tatgtattca gaaattaatg aaaataatga aatcttatat
    10021 acagaaataa tctttaagat acctctttgt attggagaag attattttaa ttttccggtt
    10081 gtatcatatg tttcaaatcc ctattcgtta ataagaggat tttatctagg ttttcataag
    10141 gaattggact gtaactatgt atttgatgat gtagagcttc atttttttag ggaagggatt
    10201 tgtgaattta acttcgaatt taaaaatcaa aattcaatca ttacagcaga attaccaagg
    10261 gagtataact atcccttgat cttgtttaat aattccaatc tggttaatca atatggaaaa
    10321 tatactttgt tagacataga caaatataaa ttagagtcta gaaagatttt tgaatttcca
    10381 gaaatttcta tcggtaactt tcttggaagt gaagcaaaat caaatagggt aatttttagc
    10441 caagataaat ttcaaattaa tggcataaag aatatggagg taaattagca tgaaatcatt
    10501 attaataaca ggtggagcag gatacatagg atcacatacg gttttggact tgttagataa
    10561 taattatgaa gtaacaatca ttgatgattt gagtaactct aagaaaaaag ttattgagtc
    10621 tattaagcag atatccaaga agagtagaaa tcttcatttt tataaaattg atttaaaaaa
    10681 tgaagaaaaa ttggaaaatg tttttaagag acataatttt gatggagtaa ttcattttgc
    10741 agggtataaa gctgttggag aatccgtggt tgaaccattg aagtattatg aaaataattt
    10801 attatcaact ataaatattt taaaactaat gaaaaaatat aaggtattta attttgtgtt
    10861 tagttcatca gctactgtat acgaaagtac tcctatcatg ccattctatg agactaatcc
    10921 attaaaagct tcaaacccgt atgggagaac aaaacagtat atagaagtac ttttaaatga
    10981 tttgtttatt tcgaattcaa attggaaaat tgtttgtctg aggtatttta atccattggg
    11041 tgcacatgaa agtggtgatt taggagagga tccaaatgga attccgaata atcttgttcc
    11101 ttacattaca caagttgcaa ttggaaaatt accatattta aatatattcg gagttgatta
    11161 cagtactcct gatgggactt gtataaggga ctatgttcac gttaacgatt tagcagacgg
    11221 acacagaaaa gcattagagt atatttttaa tacagatgaa ggtttatatg aagtaatcaa
    11281 tttaggaagt ggtgttggtt ttagtgtatt tgaaatccta cacagcttag agagtgtcat
    11341 aggctcgtat attccatata agataacttc aaggagagca ggagatatgg acgtttcaat
    11401 tgcagatatt tcaaaagcag aagagctact gggatggaag ccaaggtatg atattatgaa
    11461 aatgtgccaa gatacgtgga aatggcaaca gaaacatcca aatggatatg atgactaata
    11521 attgaaagga ttgggattaa catgcatata gtattattta gatattctgc acgggttgtt
    11581 aaactaaaat atctgtataa cagaaatgta gtaattattg cacctgaggt tcaaagaaaa
    11641 aaatatgaag attatctagc tgaaggaaat aatctaccta aggtcatttt tttagaagat
    11701 tttattctac caaatatcat cttagaaatt agaaggataa gtcaaaatac agaagttgag
    11761 agtattacaa ccttgagtga ggaagacatg gatatagtag gttttttgaa tgatcatttt
    11821 gtagaaaaaa atactcactc tgtgtctaat ttattattta aagacaaata cttcatgcgt
    11881 tcatttttag ttggagtagt aaatcaaccg tattttaggc ttttagaatc agaaaatgat
    11941 ttacgtgttt tttggaataa ttgtaaatct tctgctgcaa ttttaaaacc tagaaatgaa
    12001 gcaggaagta atggaataaa aaaagtttac cctaacgaga aaattgattc agtgtatttt
    12061 gaaaaaaact atattataga ggaatacatt gatatcgata acatgataac atgtgatggt
    12121 tattcaattg gaagtgagat taagcgattt tatgttcacg aatatgagga actattgttc
    12181 aataccttaa gttctagtgg atattatctt gtaaggacta gttcgttata taatgatagt
    12241 gaaaaaattg aatacataga aaaagcattg gaagaatgtc gcaaagtttt gaatgttttt
    12301 tctatcaatt ctgaaataac cccttttcat tttgaatggt tccttgaatt atcaactggt
    12361 aaaatagtct tttgtgaagt tggaaaaaga tttggagggg gagatattcc ccagttaatt
    12421 gaggatagtc atggagttga tgtaattaaa gaatattggg atattttgac taattcacaa
    12481 gtattgaaaa aaataaattt ttctaaagtg atttctagac ctgctaatat ctcagcaacg
    12541 tttgctttat atagaaagca aggtaaggtt atcgaggtac ctgatgaaaa agaattggct
    12601 tgggcaaaaa aagtgtacat atttattaaa ccaaatactt actataaagt atctgaaaat
    12661 gtagtcgaaa attcaatgtt tgtccaattt aattgcaaaa atagttgtga atttgagaaa
    12721 aggttagatg aacttaagca catatcacaa aagtttaaat atgtgattac tgattcggga
    12781 gaataaaatg attagagaag aacatcacaa tattctatcc attgtagcta gtaggatgat
    12841 atctcgaatc ggagatatca tgtttgattt cgccaataat acctttcttg ctggtcttaa
    12901 tccaacatct ctatcagtgg ttgcaattta tcaatcatta gaaagtatga taggtgttct
    12961 atttaattta tttggtggag ttattgcaga tagtttcaag cggaaaaaaa ttattattac
    13021 tacaaatatc ttatgtggta ttgcttgcat aactctttca tttatatccc aagaaaaatg
    13081 gttggtttat gcgatagtca taacaaatgt cattttggct tttatgagtg ctttttcagg
    13141 gccatcatac aaagctttta cgaaagaaat tgtaaaaaag gacagtatat cataacttaa
    13201 ttcattgcta gaaacaacaa gtactgtgat taaagtaaca attcctatga ttgcaatttt
    13261 cttatataag ttacttggaa tacatggtgt gttattacta gatggattat cgtttttaat
    13321 tgctgcctca ctaattttct tcattactcc tgtaaatgag gaggtggata caaaagagaa
    13381 tatgacgata agaggaatct ttgatgattt aaaaatagga tttacgtatg tatatagtca
    13441 taaacaaatt ctcactataa ttgccctttc agcacttgtt aactttttcc tagcagccta
    13501 taatttgttg ctgccataca gtaatcaaat gtttggaagt atttcaagtg ggctatatgg
    13561 aaccttttta acagccgaag cgattggtgg ctttattggt gcgatattaa gtggatttat
    13621 caataaatcc ttgtcaagca aacgtttaat gctcttttta gcatattcag gtttgatgtt
    13681 aatgctaaca gcgccgatct attatatgtt ccgcaacgtc attattttag cctttactcc
    13741 agcattattt agtctatttc tttccatttt taatatccaa tttttctcta ttgttcaaag
    13801 agacgtagat aatgagtttc ttggcagagt atttggaatc atctttacgg tagctattct
    13861 ttttatgcca ctaggtactg tttttttctc agtagtttta aatcctaaca atacttttaa
    13921 tttttttatt attggtgtat ctattacgat attatcgcta atatttagca cgctattgaa
    13981 gaggtatgat agaagttgat agatgataaa aaatagctga tatagagaat ttagagcgcc
    14041 tttggaatat atttttggaa tttaatcaat cacagttgaa tgtgaagggc aatccttttt
    14101 agaagaatac aatcaagata ccattatgct atttctttag ttcagttaaa atattgagaa
    14161 gtattacttt tattgaaaaa gcatcacaaa ggactccaat taatttttaa tgatttttct
    14221 aatctaattt tgtggttatt gacaaataaa gtctagttaa ttgctttgaa atccatggag
    14281 tggtctatat acatctgtta atgcaacgga aaattttatt gataagtagg gggtggctat
    14341 tattcagctt ttaggttctg aaagtaagag attcacatta gaaatatcat gttgaccatt
    14401 tttcaatttg ctggttagta gtaatctgga catcattaat cccttcctta acaaaattat
    14461 gtgacttttg ttaccggatt actgctgatt ttttaatagc ttataacatc tttagacggt
    14521 taatagattt tgaccgtctt tcttaatatt gtcttaccta taatagatat gcttatgaga
    14581 tatgtttaat aaattaattt tagttcaaaa tgtccagttt ggacactttg aatgatttct
    14641 tagttttata tattatactt ttctcaggag aaagctagat gtacagacgt ttgagagatt
    14701 tgagggaaga tcacgatttg acccaaaaac aaatagctaa aatactttcg tttacagact
    14761 cagcttatgc taaaattgaa cggggtgagc atacgttaac agcagatata ttggtaactc
    14821 tctcaaactt ttacgatgtc agtacagact acctattggg attgacggat tttcctgata
    14881 aaattcgctt tagaaaataa tctcctcaat ttcatagagt gtgaaaatgc gaagattttt
    14941 tttatttgtt ctttgacaat tgaatagtcc aaaatggtac tttcctcatt tgtggagcag
    15001 atttgaatgg ttcgccatga taagagcgat attaaaacca tcaataaaat agagcgatac
    15061 tttatatgcc atgatacaaa tgatatacaa tgatacttct gaccgttcag gctgccaccg
    15121 taaaagagca gcaagtgaaa ttcttatgat gacttcatca gtcatgccat gttgaatgtg
    15181 tgagtttgtt agataaacgc aattaatcct caaaaggttc cccgaacctt ttgagttcta
    15241 cagacgcatc acgtggagtg tgtaagcttg ttgctaaaag cgtaaaaacc ttggaacgaa
    15301 aggaataata gacttcctgc gaaacaaaaa tataatacaa taaaactatg aatgatgaag
    15361 caagtaaaca attgagcgat agccgtttca agatccttgt aggtgttcag cgcacgactt
    15421 ttgaagagat gttagcggtg ttaaaaacag cttatcaacg taaacgcgca aaaggtggac
    15481 gaaaaagcaa attaagccta gacgatctcc ttatggtaac tattcaatac atgcgagaat
    15541 agcgcactta tgaacaaatt gcggctgatt ttggcattca cgaaagcaac ataattagtc
    15601 ggagtcaatg gattgaagca actcttattc aaaatggttt tacgatttca aattctgcct
    15661 taattctgta aaaacagtaa aattcgaagg attgtaaggt aagagttttt ttctttctga
    15721 aaaaatggta taatagcaat caaaactaga aaataaaacg gaatttggaa cagatttgtc
    15781 tgtatcctag tagagtggtg atactatgaa gattagtaag aggcacttat taaattattc
    15841 catcttgatt ccctacttgc ttttatctat tttgggcttg attgtggtct attcgaccac
    15901 cagtgctatt ttaattgaag aaggcaagag cgccttgcag ttggttcgaa accaaggaat
    15961 cttttggatt gttagtttga tactgattgc cttaatttat aaattgagac tagatttttt
    16021 gagaaatgag cgactaatca ttttagttat attaatagaa atgcttttat tgttcttggc
    16081 tcgttttatt ggtatttcag taaacggggc atacggttgg atttcggttg caggagtaac
    16141 tattcagcca gctgagtact taaaaatcat tattatttgg tatttagctc accgattctc
    16201 caaacagcaa gaagaaatag ctacttatga ttttcaagtt ttgactcaaa atcaatggct
    16261 tccccgtgct tttaatgatt ggcgattcgt tctcctagtt ctgattggaa gtttgggaat
    16321 tttccctgat ttaggaaatg cgactatttt agtcttggtt tccttgatta tgtatacagt
    16381 tagtggaatc gcttatcgct ggttttcaac cattctggcg ctcgtatctg ccacttctgt
    16441 ctttgtcttg accactatca gcctaatcgg tgttgagacc ttttcaaaaa ttccagtatt
    16501 tggctatgta gccaagcgct ttagtgcctt ttttaatcct tttgccgatc gtgctgatgc
    16561 aggtcaccag ttagctaatt cttattttgc catggtcaat ggcggttggt ttggtctagg
    16621 tcttggaaac tcgattgaaa aacgaggtta tttgccagaa gctcatacag actttgtctt
    16681 ttctatcgtg attgaagaat ttggctttgt tggtgccagt cttattttag ctctcttgtt
    16741 tttcatgatt ttgcggatta tcttggtcgg tatccgagcg gagaatcctt tcaatgccat
    16801 ggttgcactc ggtgtcggag ggatgatgtt ggttcaggta tttgtcaata tcggagggat
    16861 ttcgggcttg attccatcta caggagtgac tttccccttc ttatcccagg gtggaaatag
    16921 tcttctagtc ttatcagtgg cagtagcctt tgtcttaaat attgatgcca gtgaaaaacg
    16981 cgctaaattg taccgagaat tggaaaatca accaatgaac cttctgttga agtaggataa
    17041 agaaaggata gtttatgtct cttcaaaaat tagaaaatta tagtaataaa agtgttgtgc
    17101 aagaagaagt cttgattcta acagaattac tggaagatat tactaaaaat atgcttgccc
    17161 cagagacctt tgaaaaaata atacagttga aagaattatc aacgcaggaa gattatcaag
    17221 gtctaaaccg tctagtgact agcttatcaa atgatgaaat ggtctatatt tcacgctatt
    17281 tctctatctt gcctcttttg attaatattt cagaggatgt ggatttagct tatgaaatca
    17341 atcatcaaaa taatattgat caggactatt taggtaaatt atctacaacg attaaattgg
    17401 tagcagaaaa ggaaaatgcc gttgagatcc tagaacactt gaatgttgtc cctgttttga
    17461 cagcccatcc aacacaagtg caacgcaaaa gtatgttgga tttaacaaat catattcata
    17521 gtcttttgcg taaataccgt gatgttaagt tggggttgat caataaagat aaatggtaca
    17581 atgatttgcg tcgttacatc gaaattatca tgcagacaga catgattcgt gagaaaaaat
    17641 taaaagtgac taacgaaatc acgaatgcta tggaatatta taacagctcc tttttgaaag
    17701 ctgtacctca tttgacgacg gagtataagc gcttagcgca agcgcatggt ctgaatttaa
    17761 aacaggctaa accaatcacc atgggtatgt ggataggtgg tgaccgtgat ggaaatccat
    17821 ttgttacagc aaagaccttg aagcagtctg cactcactca gtgtgaagtc atcatgaact
    17881 actatgataa aaagatttac caactttatc gtgaattttc tctttcaact agcattgtca
    17941 acgtcagcaa gcaagtcaga gaaatggctc gtcaatccaa ggataactcg atttaccgcg
    18001 aaaaagagct ttaccgtcgt gccttgtttg atattcaatc aaaaattcag gcaactaaaa
    18061 cctatctgat tgaggatgaa gaagttggga ctcgttatga aaccgccaat gatttctaca
    18121 aggatttgat tgccattcga gattctctac tagaaaataa gggcgagtcc ttgatttcag
    18181 gtgattttgt ggaattattg caggcagtag agatatttgg tttttactta gcatcaattg
    18241 atatgcgaca agactctagc gtctatgaag cctgtgtggc agaactcttg aaatcagcag
    18301 gaattcattc tcgttatagc gagttgagcg aagaagaaaa gtgtgacctt ctcttgaaag
    18361 aattagaaga agatccccga attctttctg cgactcacgc agaaaaatca gaattattag
    18421 caaaagaatt agctattttt aagacggctc gtgttttgaa agataagttg ggagatgatg
    18481 tcatccgtca gaccatcatt tcacatgcaa ccaacctttc tgatatgcta gaattagcta
    18541 ttctgttaaa agaagtagga ctggtggata cggaaagggc gcgtgttcag attgttcccc
    18601 tttttgaaac aattgaagac ttggatcatt cagaggaaac aatgagaaaa tatctttctc
    18661 ttagccttgc caaaaaatgg attgactcac gaaataacta ccaagaaatc atgcttggct
    18721 actctgacag taataaagat ggcggttact tgtcatcatg ttggaccctc tacaaggctc
    18781 aacaacaatt gactgctatt ggagatgaat ttggcgttaa ggttaccttc ttccatggtc
    18841 gtggtggtac tgtcggtcgt ggtggtgggc caacctatga agccattaca tctcaaccgc
    18901 tcaagtctat caaggatcgt atccgtttga cggagcaggg tgaagtaatt gggaataaat
    18961 acggtaacaa agacgccgct tactataacc ttgaaatgct agtatcggca gctattaacc
    19021 gtatgattac tcagaagaag agcgatacca ataccccaaa tcgttatgaa gccattatgg
    19081 atcaagtagt ggaccgtagt tacgatatct accgtgattt ggtctttggt aatgagcatt
    19141 tctatgatta tttcttcgag tcaagtccaa tcaaggctat ttcaagtttt aatattggtt
    19201 ctcgtccagc cgctcgtaag actattactg aaatcggtgg tttgcgtgcc atcccttggg
    19261 tattctcatg gtcacagagt cgtgttatgt tccctggatg gtacggggtt ggttcaagct
    19321 tcaaggaatt tatcaataaa aatccagaga atattgctat cttacgagat atgtaccaaa
    19381 attggccttt cttccaatcg cttctttcaa atgttgatat ggttttgtca aaatcaaata
    19441 tgaatattgc ttttgaatat gctaaacttt gtgaagacga gcaagttaag gccatctatg
    19501 agattatttt aaatgaatgg caagttacta agaacgttat cttggctatt gaaggacatg
    19561 acgaactctt agctgacaat ccatatctaa aagctagtct ggattaccgt atgccttact
    19621 ttaatattct caactatatt cagttagagt tgattaaacg ccaacgtcgt ggagaattgt
    19681 ccagtgatca agaacgattg attcatatca ccatcaacgg aattgcgaca ggattgcgta
    19741 attcaggttg ataattttca agagtgaatg ctaaaagtga atatcaaaaa aattctaata
    19801 gactattgac aagtagttta aaaatgatat aatttaacca ttcagaaaag taatcataca
    19861 aactttttag agagtctgtg gtagctgaaa acagataagt ggcgatgatg aaaattgggc
    19921 tgaatgctat ttagaatttg aaattataaa aattcggtaa gcacacctta cagtgcatct
    19981 cgttattgcg agactgagcg atagggaaat tccctataat tgaggtggta ccgcgcatcg
    20041 acgtcctcac acaagttttt tgtgtgagga tttttttgat ggaggttagt atggaaagaa
    20101 aacgatggcg tcgcttgttt agataagtga aatatgttaa aggaaataaa aaggagaaac
    20161 agaatgaaaa ataaacgttt aattggaatt attgctgcat tagcagtctt agtagcagga
    20221 agcttgattt attcttcaat gaataaatca gaagctcaga ataataagga tgagaagaaa
    20281 ataactaaga ttggtgtgct tcaatttgtg agccatccat cccttgattt gatttataaa
    20341 gggatccaag atggacttgc agaagaagga tataaagatg atcaagttaa aattgatttt
    20401 atgaactcag aaggtgacca aagtaaggtt gcgacaatga gtaaacaatt ggttgcaaat
    20461 gggaatgacc ttgtggttgg tatcgcaaca ccagcagccc aagggttggc tagtgcaaca
    20521 aaagacctac cggttatcat ggccgctatt acagacccaa ttggtgctaa cttggttaaa
    20581 gatttgaaaa aaccaggtgg caacattaca ggggtatctg accacaatcc agctcaacaa
    20641 caagttgaac tcatcaaggc tctgacaccg aatgtgaaaa caatcggagc tctttactca
    20701 agtagcgaag acaattcaaa aacacaggtc gaagaattta aggcttatgc tgaaaaagca
    20761 ggtctgacag tggaaacatt tgcagttcct tcaacaaatg aaattgcctc aactgtcact
    20821 gttatgacta gcaaggtaga tgctatttgg gttccaattg ataacaccat tgcatcagga
    20881 tttccaacgg ttgtctctag caatcaaagt tctaagaaac caatttatcc cagtgcgaca
    20941 gctatggtag aagtaggtgg tttggcatca gttgtaattg accaacatga ccttggtgtg
    21001 gcaacaggta aaatgattgt gcaagtcttg aaaggtgcaa aaccagccga taccccagtc
    21061 aatgtctttt caactggtaa gtcagtcatc aataaaaaaa tagcacaaga actaggtatt
    21121 actatccctg agtctgttct caaagaagca ggacaagtca tcgaataaat aaggtaggga
    21181 ggaggagact cttcccattt tttaaaaaga tgaatataga aaggattaaa taaaatatga
    21241 ttgtttccat tatttctcaa ggatttgtct gggctattct aggtctggga atctttatga
    21301 catttaggat tttaaacttt ccagatatga cgacagaagg ttccttccct cttgggggag
    21361 ctgttgctgt cactttgata accaaaggcg tgaacccatt tttagcgaca cttgttgctg
    21421 taggagcagg ttgtttggct ggaatggcag caggccttct ttatacaaaa gggaagatcc
    21481 caaccttgct ctcagggatt ttggtgatga cttcttgtca ctcaatcatg ctcttgatta
    21541 tgggacgtgc gaatttaggc ctgcttggaa ccaagcaaat tcaggatgtt ttgccttttg
    21601 attcggattt gaatcaactc ttgacaggtc tcatctttgt gagtattgtt attgctctca
    21661 tgctcttttt cttggacact aaactcggac aagcctatat tgctacaggg gataatcctg
    21721 atatggctag aagtttcggg attcatactg gacgcatgga gctcatgggc ttggtcttat
    21781 caaatggtgt gattgccctt gcaggtgccc tcattgctca gcaagaaggt tatgccgatg
    21841 tgtctcgagg gatcggggtt atcgttgtgg ggcttgcaag tttgattatt ggagaagtta
    21901 ttttcaagag tttgagcttg gcagagcgtt tggttactat cgttgtaggt tctatcgctt
    21961 atcaattttt agtgtgggca gttatcgcac ttggctttaa tacaagttac cttcgtttat
    22021 acagtgcctt gattttagca gtctgcctca tgattccaac atttaagcaa acaatcttga
    22081 aaggagccaa gttaagcaaa tgacagcaat tgtagaatta aaaaatgcaa ccaaaatcgt
    22141 taaaaatggc tttgatgaag aaaagattat tttaaatgat gtttccttag aaatttttga
    22201 acgggacttt atcacgattt tgggcggaaa tggtgctgga aaatcaaccc tctttaacac
    22261 tatagcaggg accttatcac taactagtgg aactatccgt attttaggtg aagatctcac
    22321 taagttttca cccgagaagc gtgccaagta cctgtctcgt gtcttccaag atccaaagat
    22381 ggggacagct ccccgtatga cggtcgctga aaatctttta atcgccaagt ttcgtggtga
    22441 aaagcgtgga ttgttaccac gacgcttgac tagctataag gatgaatttc aggtaaccat
    22501 tgaaaaagta ggaaatggtc ttgagaaaca cttgaataca ccgattgagt tcttatcagg
    22561 tggacaaaga caggctttga gtctcttgat ggcaaccttg aagcgacctg aattactcct
    22621 gttagatgag catactgctg ccctggatcc aaagactagt gttgctttga tggaattgac
    22681 agatgaattt gttaagaaag atcagctaac agcccttatg attactcatc atatggaaga
    22741 tgctctcaaa tacggcaatc gcttgattgt catgaaagaa ggacggatta tccaagattt
    22801 aaaccaagaa gaaaaagcaa aaatgaaaat ctctgattat tatcaactct ttgaataaag
    22861 tagggaaaat gagtgaaata gtttactttt tttctgaaat aaagtatact atatatagta
    22921 tactatgata acatggaggt attgtgtatg gttgacaaac aagtcattga agaaatcaaa
    22981 aacaatgcca acattgtgga agtcatagga gatgtgattt ctttacaaaa ggcaggacgg
    23041 aactatctag ggctctgtcc ttttcatggc gaaaaaacac catctttcaa cgttgtagag
    23101 gataagcagt tttatcactg tttcggttgt ggtcgctcag gtgatgtctt taagttcatc
    23161 gaggagtacc aaggggttcc ctttatagag gcagtccaaa tcttaggtca gcgtgttgga
    23221 attgaggttg aaaaaccgct ttatagtgag cagaagtcag cctcacctca ccaagctctt
    23281 tatgatatgc acgaagatgc agccaaattt taccatgcta ttctcatgac aacgactatg
    23341 ggagaagagg ccagaaatta cctttatcag cggggtttga cagatgaagt gcttaaacat
    23401 ttttggattg gtttagcacc tccagaacga aactatctct atcaacgttt gtctgatcag
    23461 tatcgtgaag aggatttact ggattcaggc ctgttttatc tctcggatgc caatcaattt
    23521 gtagacacct ttcacaatcg cattatgttt cccctgacaa atgaccaagg aaagatcatt
    23581 gccttctcag gtcgtatctg gcaaaaaacg gattcacaaa cttctaagta taaaaacagc
    23641 cgatcgactg caatttttaa caaaagttac gaattatatc atatggatag ggcaaaaaaa
    23701 tcttctggaa aagctagtga gatttacctg atggaaggat tcatggatgt tattgcagcc
    23761 tatcgggttg gaatcgaaaa tgctgtggcg tcgatgggaa cggccttgag tcgagagcat
    23821 gttgagcatc tgaaaaggtt aaccaagaaa ttggttcttg tttacgatgg agataaggct
    23881 gggcaagccg cgatattgaa agcattggat gaaattggtg atatgcctgt gcaaatcgtc
    23941 agcatgcctg ataacttgga tcctgatgag tatctacaaa aaaatggtcc agaagacttg
    24001 gcctatctat taacgaaaac tcgtattagt ccgattgagt tctacattca tcagtacaaa
    24061 cctgaaaaca gtgaaaatct gcaggctcag attgagttta ttgaaaaaat agctcccttg
    24121 attgttaaag aaaagtccat cgctgctcaa aacagctata ttcatatttt agctgacagt
    24181 ctggcgtcct ttgattatgc ccagattgag cagattgtta atgagagtcg tcaggtgcaa
    24241 aggcagaatc gcatggaaag aatttccaga ccgacgccaa tcaccatgcc tgtcaccaag
    24301 cagttatcgg ctattatgag ggcagaagcc catctactct atcggatgat ggaatcccct
    24361 cttgttttga acgattaccg tttgcgagaa gactttgcat ttgctacacc tgaatttcag
    24421 gtcttatatg acttgcttgg ccagtatgga aatcttcctc cagaagtttt agcagagcag
    24481 acagaggaag ttgaaagagc ttggtaccaa gttttagctc aggatttgcc tgctgagata
    24541 tcgccgcagg aacttagtga agtagagatg actcgaaaca aggctctctt gaatcaggac
    24601 aatatgagaa tcaaaaagaa ggtgcaggaa gctagccatg taggagatac agatacagcc
    24661 ctagaagaat tggaacgttt aatttcccaa aagagaagaa tggagtaata atggcaacaa
    24721 aacaaaaaga agtaacaaca tttgacgtac aggtagcaga atttatccgt aatcataagc
    24781 aaaaagggac agcaacagat gatgaaatca atgcaagttt ggttattcct tttaccttgg
    24841 acgctgatgg gattgaagat ctcttgcaac ggattcagga tgcaggaatt tctatcacag
    24901 ataacgaagg aaatccaagt gcgcgtgttc ttagcaatga agaagaacca gaactcagcg
    24961 atgaggactt gattgggtca acttctgcta aggtcaatga ccctgtccgt atgtacttga
    25021 aagaaatagg ggtcgttcct ctcttgacca atgaagagga gaaagagttg gcactggctg
    25081 ttgaagctgg tgatatcgaa gccaaacaac gtcttgcgga agccaatctt cgtttggttg
    25141 tttccattgc caaacgctat gtcggtcgtg gtatgcagtt ccttgacttg attcaagaag
    25201 gaaatatggg cttgatgaag gcggttgaca agtttgacta ttctaaaggg ttcaagtttt
    25261 caacttatgc aacttggtgg attcgtcagg ctatcactcg tgctattgcg gaccaagctc
    25321 gtaccatccg tatcccagtt cacatggttg aaactatcaa taaattggtt cgtgaacagc
    25381 ggaatctcct tcaagaattg gggcaagatc cgacaccaga acagattgct gaacgaatgg
    25441 atatgacacc tgataaggtt cgtgaaatct tgaagattgc ccaagaacca gtatctcttg
    25501 aaactcctat cggtgaagag gacgatagcc acctcggaga ctttatcgaa gatgaagtga
    25561 ttgaaaatcc agtggattat acgactcgta tcgtcttgcg tgagcaattg gatgaaatct
    25621 tagatactct tacagaccgt gaagaaaatg ttctgcgtct acgttttgga ctagatgatg
    25681 gaaaaatgcg cacacttgaa gatgtgggga aagtctttaa cgtaactcgt gagcgtatcc
    25741 gtcagattga agcaaaggct ttgagaaaac tacgccaacc aagtcgtagc aaaccgcttc
    25801 gtgattttat tgaagactaa gagtgaggaa aatatggctt atacagaaga gcaaattgaa
    25861 aacatcaaaa cacggatttt aacagccttg gaagaagtca tcgaccctga gttgggaatc
    25921 gatattgtca atcttggttt gatctatgag attcgttttg acggtgacac agggcaaaca
    25981 gagattgaca tgactttgac aactatgggt tgtcccttag cagacctttt gacagaccag
    26041 atttatgatg ctatgataga ggttccagaa gtaacggata ctgaggttaa attagtctgg
    26101 tatccagcct ggacagttga aaaaatgagt cgctatgccc gcattgccct aggcattaag
    26161 taaacatata aaagcatgtg agagactgtt ggaaaagcga ggaaatttcc cctcttttcc
    26221 tctagtctct cctttctttt gctgatttta ttcaaagaaa atgatataat agtagttatg
    26281 gagaaaaaga aattacgcat caatatgttg agttcaagtg agaaagtagc aggacaggga
    26341 gtttcaggtg cttaccgtga attagttcgt cttcttcacc gtgctgccaa ggaccaattg
    26401 attgttacag aaaatcttcc aatcgaggca gatgtgactc actttcatac gattgatttt
    26461 ccctattatt tatcaacctt ccaaaagaaa cgctcaggga gaaagattgg ctatgtgcat
    26521 ttcttgccag ctacacttga gggaagtttg aaaattccat ttttcttaaa gggaattgtg
    26581 aaacgctatg tattttcttt ttacaaccgg atggagcact tggttgtggt caatcctatg
    26641 tttattgagg atttggtagc agctggtatt ccacgtgaaa aagtgaccta tattcctaac
    26701 tttgtcaaca aggaaaaatg gcatcctcta ccacaagaag aggtagttag actgcgcaca
    26761 gatcttggtc ttagtgacaa tcagtttatc gtagtaggtg ctgggcaagt tcagaaacgt
    26821 aaagggattg atgactttat ccgtctggct gaggaattgc ctcagattac ctttatctgg
    26881 gctggtggct tctcttttgg tggtatgaca gatggttatg aacactataa gaaaattatg
    26941 gaaaatcccc ctaaaaattt gatttttcca ggcattgtat cgccagagcg gatgcgcgaa
    27001 ttgtatgctc tagcggatct tttcttgttg cctagttaca atgagctctt tcctatgact
    27061 attttagaag ctgcgagttg tgaggctcct attatgttgc gtgatttaga tctctataag
    27121 gtgattttgg agggaaatta tcgggcgaca gcgggtagag aagagatgaa agaggctatt
    27181 ttggaatatc aagcaaatcc tgctacctta aaagatctca aagaaaaggc taagaatatt
    27241 tccagagagt attctgaaga gcatctgtta caaatctggt tggactttta tgagaaacaa
    27301 gccgctttag ggagaaagta aaaagtgagg taatctatgc gaattggttt atttacagat
    27361 acctattttc ctcaggtttc tggtgttgcg accagtattc gaaccttgaa aacagaactt
    27421 gaaaagcagg gacatgctgt ttttatcttt acgacgacag ataaggatgt caatcgctac
    27481 gaagattggc aaattatccg cattccaagt gttcctttct ttgcttttaa ggatcgtcgc
    27541 tttgcctacc gaggttttag caaggcactt gaaattgcta aacagtatca gctagatatt
    27601 atccatactc agacagaatt ttctcttggc ctgttgggga tttggattgc gcgtgaattg
    27661 aaaattccag tcatccatac ctatcacacc cagtatgaag actatgtcca ttatattgct
    27721 aaggggatgt tgatccggcc gagtatggtc aagtatctgg ttagaggttt cctgcatgat
    27781 gtggatgggg ttatttgccc tagtgagatt gtccgtgact tgctatctga ttataaggtc
    27841 aaggttgaaa aacgggtcat tcctactgga attgaattag ccaagtttga gcgtccggaa
    27901 atcaagcagg aaaatttgaa agaactgcgt agtaaactag ggattcaaga tggtgaaaag
    27961 acgttgctta gtctttcgag aatctcctat gaaaaaaata ttcaagcagt tttagtagcc
    28021 tttgctgatg ttctgaaaga ggaagacaag gttaaactgg tagtagctgg ggatggccct
    28081 tatctgaatg acctcaaaga gcaagcccag aacctagaga ttcaagactc agtcatcttt
    28141 acagggatga ttgctcctag tgagacggct ctttactata aagcggcgga tttcttcatt
    28201 tcggcatcga caagcgaaac gcaaggtttg acctacttgg aaagcttagc cagtggaaca
    28261 cctgtcattg ctcacggaaa tccttatttg aacaacctca tcagtgataa aatgtttgga
    28321 accttgtact atggagaaca tgatttggct ggtgctattt cggaagccct gattgcaaca
    28381 ccagacatga atgagcatac cttatcagag aaattgtatg agatttcagc tgagaacttt
    28441 gggaaacgag tgcatgagtt ttatctggat gccattattt caaataactt ccagaaagat
    28501 ttggctaaag atgatacggt cagtcagcgt atctttaaga cagttttgta tcttccgcaa
    28561 caggtggttg ctgtacctgt aaaaggatct agacgcatgt tgaaggcttc aaaaacacag
    28621 ttgatcagta tgagagacta ttggaaagac catgaagaat agaaagagga acagctatga
    28681 aaaaaacaat taatgagaag cggtcgtgat aaaaagattg cgggtgtttg tgctggggtg
    28741 gcccattatc tggatatgga tccgactatc gttcaagtca tttggggtgt tcttacttgc
    28801 tgttacggag ctggaattgt agcttacatt attttatgga ttatcgcacc agtagcaact
    28861 gactattgaa aactagctca attcatgcta agataataga aaatagaatg taacgaagga
    28921 gagaaaaatg gcatttggag ataatggaaa tcgtaaaaaa actatgtttg agaaaataac
    28981 cttgtttatc gtgattatca tgctagtagc aagtttattg ggaatttttg caactgcaat
    29041 tggtgccctc agtaatctat aaaatagatt caagaaaatt tagtgactgg gatttcccag
    29101 ccctttttta aagtgagaag aaataatgag tatgttttta gatacagcta agattaaggt
    29161 caaggctggt aatggtggcg atggtatggt tgcctttcgt cgtgaaaaat atgtccctaa
    29221 tggaggccct tggggtggtg atggtggtcg tggaggcaat gtggtcttcg ttgtagacga
    29281 aggactacgt accttgatgg attttcgcta caatcgtcat ttcaaggctg attctggtga
    29341 aaaagggatg accaaaggga tgcatggtcg tggtgctgag gaccttagag ttcgagtacc
    29401 acaaggtacg actgttcgtg atgcggagac tggcaaggtt ttaacagatt tgattgaaca
    29461 tgggcaagaa tttatcgttg cccacggtgg tcgtggtgga cgtggaaata ttcgtttcgc
    29521 gacaccaaaa aatcctgcac cggaaatctc tgaaaatgga gaaccaggtc aggaacgtga
    29581 gttacaattg gaactaaaaa tcttggcaga tgtcggttta gtaggattcc catctgtagg
    29641 gaagtcaaca cttttaagtg ttattacctc agctaagcct aaaattggtg cctaccactt
    29701 taccactatt gtaccaaatt taggtatggt tcgcacccaa tcaggtgaat cctttgcagt
    29761 agccgacttg ccaggtttga ttgaaggggc tagtcaaggt gttggtttgg gaactcagtt
    29821 cctccgtcac atcgagcgta cacgtgttat ccttcacatc attgatatgt cagctagcga
    29881 aggccgtgat ccatatgagg attacttagc tatcaataaa gagctggagt cttacaatct
    29941 tcgcctcatg gagcgtccac agattattgt agctaataag atggacatgc ctgagagtca
    30001 ggaaaatctt gaagaattta agaaaaaatt ggctgaaaat tatgatgaat ttgaagagtt
    30061 accagctatc ttcccaattt ctggattgac caagcaaggt ctggcaacac ttttagatgc
    30121 tacagctgaa ttgttagaca agacaccaga atttttgctc tacgacgagt ccgatatgga
    30181 agaagaaact tactatggat ttgacgaaga agaaaaagcc tttgaaatta gtcgtgatga
    30241 cgatgcgaca tgggtacttt ctggtgaaaa actcatgaaa ctctttaata tgaccaactt
    30301 tgatcgtgat gaatctgtca tgaaatttgc ccgtcagctt cgtggtatgg gggttgatga
    30361 agcccttcgt gcgcgtggag ctaaagatgg ggatttggtc cgcattggta aatttgagtt
    30421 tgaatttgta gactaggaga ctggtatggg agataaaccg atatctttcc gagatgcgga
    30481 tggtaatttt gtttccgccg cagacgtttg gaatgaaaag aaattggaag aactatttaa
    30541 tcgtctcaat ccaaatcgtg ccttgagatt ggcacgaact aaaaaggaaa atccatctca
    30601 gtaaagaagc taaaaaatcc cgtgcctcat cagacacggg attttgtggt acgacaggca
    30661 tgtatagcaa actgaatctg gaatagcaca gcatatcttc taaaatattg ttataaattg
    30721 atttgaattt caaaattaaa ttgtttgatt cttatttcaa tttgttatag tatatctgat
    30781 gtcaaagttc tcggcgagtc aaatagcgat tcccaagcct gactatcgtg aggtagcgga
    30841 ttaaaatggt ctggggatag accgttttaa gtctgacgct ggaaataaga attgtcagaa
    30901 gaagggatag cgaaatcgtg gctctacgaa caggaacgtg ataataaggc gtatatagcg
    30961 gataagaggg cctcaaactc taaagtccaa aaaggtagtc gtaacctata tgcgtaaatc
    31021 acgagagtaa ttgaattcgt actaagattt tctattttca ctgtaacctt ttaacgtcct
    31081 tatatcttgt atacacgagg aaagatgtac gacttatccc gtgaggtcta tcactataaa
    31141 gagaaaacga cagatagaag tgatcctgag tcacggttat ctttaaaata gattgtctga
    31201 taggacggta tgtataaaac gcttctgtga actgagagaa gggggagaag ttcttgctaa
    31261 aatttagttg aacagccgta ttccgatact tagataagag atctagtctt agctcctact
    31321 cggtttcagg ggataaaaaa ggggcaatag cgattcgaga aagattatac tcttcgaaaa
    31381 tctcttcaaa tcacgtcaat atcgccttgc cgtacgtgta ggatactgac tacgtcagt
//
LOCUS       DAVBOG010000025        30962 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.025, whole genome shotgun sequence.
ACCESSION   DAVBOG010000025 DAVBOG010000000
VERSION     DAVBOG010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30962
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.025"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            289..2790
                     /locus_tag="VQ865_001202"
     CDS             289..2790
                     /locus_tag="VQ865_001202"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HET3135537.1"
                     /translation="MSFYNHKEIEPKWQGYWAEHHTFKTGTDASKPKFYALDMFPYPS
                     GAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWDAFGLPAEQYAMDTGNDPAEFTA
                     ENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
                     ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLDELDWSESIKD
                     MQRNWIGKSTGANVTFKVKGTDKEFTVFTTRPDTLFGATFTVLAPEHELVDAITSTEQ
                     AEAVADYKHQASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEIPIWIADYVLASYGT
                     GAVMAVPAHDQRDWEFAKQFDLPIVEVLEGGNVEEAAYTEDGLHVNSDFLDGLNKEDA
                     IAKIVACLEEKGCGQEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLV
                     LPVTKDIRPSGTGESPLANLTDWLEVTREDGVKGRRETNTMPQWAGSSWYYLRYIDPH
                     NTEKLADEDLLKQWLPVDIYVGGAEHAVLHLLYARFWHKFLYDLGVVPTKEPFQKLFN
                     QGMILGTSYRDHRGALVATDKVEKRDGSFFHVETGEELEQAPAKMSKSLKNVVNPDDV
                     VEQYGADTLRVYEMFMGPLDASIAWSEEGLEGSRKFLDRVYRLITSKEIIAENNGALD
                     KVYNETVKAVTEQIESLKFNTAIAQLMVFVNAANKEDKLYVDYAKGFIQLIAPFAPHL
                     AEELWQTVAATGESISYVAWPTWDESKLVEDEIEIVVQIKGKVRAKLMVAKDLSREEL
                     QEIALADEKVKVEIDGKEIVKVISVPNKLVNIVVK"
     gene            2984..3679
                     /locus_tag="VQ865_001203"
     CDS             2984..3679
                     /locus_tag="VQ865_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001144916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135538.1"
                     /translation="MPVNEYGQMIGESMEGYTPGELPSIDFLEGRYARIEALSVEKHA
                     EDLLAVYGPDTPQEMWTYLFQEPVADMGELVSLLHQMMARKDRFYYAIIDKATGKALG
                     SFSLMRIDQNNRVIEVGAVTFSPELRGTRIGTEAQYLLARYVFEELNYRRYEWKCDAL
                     NLPSRRAAERLSFIYEGTFRQAVVYKGRTRDTDWLSMIDKDWPQVKDRLETWLRPENF
                     DKNGQQYKSLREL"
     gene            3691..4107
                     /locus_tag="VQ865_001204"
     CDS             3691..4107
                     /locus_tag="VQ865_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135539.1"
                     /translation="MITIKKQEIVKLEDVLHLYQAVGWTNYTHQPEMLEQALSHSLVI
                     YLALDGDAVVGLIRLVGDGFSSVLVQDLIVLPIYQRQGIGSALMKEALEDYKDAYQVQ
                     LVTEETERTLGFYRSMGFEILSTYNCIGMTWMNRKK"
     gene            complement(4922..5014)
                     /locus_tag="VQ865_001205"
     CDS             complement(4922..5014)
                     /locus_tag="VQ865_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HET3135540.1"
                     /translation="MMELVLKTIIGPIVVGVVLRIVDKWLNKDK"
     gene            5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ865_001206"
     CDS             5175..6146
                     /gene="ruvB"
                     /locus_tag="VQ865_001206"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000502070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HET3135541.1"
                     /translation="MGDEELVERTLRPQYLREYIGQDKVKDQLQIFIEAAKMRDEALD
                     HVLLFGPPGLGKTTMAFVIANELGVNLKQTSGPVIEKAGDLVAILNELEPGDVLFIDE
                     IHRLPMSVEEVLYSAMEDFYIDIMIGAGEGSRSVHLELPPFTLIGATTRAGMLSNPLR
                     ARFGITGHMEYYAHADLTEIVERTADIFEMEITHEAASELALRSRGTPRIANRLLKRV
                     RDFAQIMGNGVIDDIITDKALTMLDVDHEGLDYVDQKILRTMIEMYSGGPVGLGTLSV
                     NIAEERETVEDMYEPYLIQKGFIMRTRSGRVATAKAYEHLGYEYSEK"
     gene            6127..6699
                     /locus_tag="VQ865_001207"
     CDS             6127..6699
                     /locus_tag="VQ865_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase family protein"
                     /protein_id="HET3135542.1"
                     /translation="MNTVKNKQEILEAFRENPDMMAILTIIRDLGLKDSWLAAGSVRN
                     FIWNLLSDKSPFDHETDIDVIFFDPDFSYEETLLLEKKLREDFPQYQWELKNQVYMHQ
                     HSPHTASYTSSRDAMSKYPERCTTVGLRLNEESDFELYAPYGLEDILNFQVRPTPHFL
                     ENEDRMELYQTRLSKKNWQEKWKNLIFKNT"
     gene            6930..7688
                     /locus_tag="VQ865_001208"
     CDS             6930..7688
                     /locus_tag="VQ865_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000466694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HET3135543.1"
                     /translation="MFGFFKKDKAVEVEVPTQVPAHIGIIMDGNGRWAKKRMQPRVFG
                     HKAGMEALQTVTKAANKLGVKVITVYAFSTENWTRPDQEVKFIMNLPVEFYDNYVPEL
                     HANNVKIQMIGETDRLPKQTFEALTKAEELTKNNTGLILNFALNYGGRAEITQALKLI
                     SQDVLDAKINPGDITEELIGNYLFTQHLPKDLRDPDLIIRTSGELRLSNFLPWQGAYS
                     ELYFTDTLWPDFDEAALQEAILAYNRRHRRFGGV"
     gene            7697..8500
                     /locus_tag="VQ865_001209"
     CDS             7697..8500
                     /locus_tag="VQ865_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000189872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HET3135544.1"
                     /translation="MTQDLQKRTLFAGIALAIFLPILMIGGLLLQIAIGIIAMLAMHE
                     LLKMRGLETMTMEGLLTLFATFALTIPLENYLTFLPVDGNVVAYSVLISIMLGTTVFS
                     KSYTIEDAVFPLAMSFYVGFGFNALLDARVAGLDKALLALCIVWATDSGAYLVGMNYG
                     KRKLAPRVSPNKTLEGALGGILGAILVTIIFMIVDSTVALPYGIYKMSVFAIFFSIAG
                     QFGDLLESSIKRHFGVKDSGKFIPGHGGVLDRFDSMLLVFPIMHLFGLF"
     gene            8522..9781
                     /gene="rseP"
                     /locus_tag="VQ865_001210"
     CDS             8522..9781
                     /gene="rseP"
                     /locus_tag="VQ865_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000900658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HET3135545.1"
                     /translation="MLGILTFILVFGIIVVVHEFGHFYFAKKSGILVREFAIGMGPKI
                     FAHIGKDGTAYTIRILPLGGYVRMAGWGDDTTEIKTGTPVSLTLADDGKVKRINLSGK
                     KLDQTALPMQVTQFDFEDKLFIKGLVLEEEKTFAVDHDATVVEADGTEVRIAPLDVQY
                     QNATIWGKLITNFAGPMNNFILGVVVFWVLIFMQGGVRDVDTNQFHIMPQGALAKVGV
                     PETAQITKIGSHEVSNWESLIQAVETETKDKTAPTLDVTISEKGSDKQVTVTPEDSQG
                     RYLLGVQPGVKSDFLSMFVGGFTTAADSALRILSALKNLIFQPDLNKLGGPVAIFKAS
                     SDAAKNGIENILYFLAMISINIGIFNLIPIPALDGGKIVLNILEAIRRKPLKQEIETY
                     VTLAGVVIMVVLMIAVTWNDIMRLFFR"
     gene            9794..11647
                     /locus_tag="VQ865_001211"
     CDS             9794..11647
                     /locus_tag="VQ865_001211"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HET3135546.1"
                     /translation="MKQSKIPIPTLREMPSDAQVISHALMLRAGYVRQVSAGVYSYLP
                     LANRVIEKAKNIMRQEFEKIGAVEMLAPALLSAELWRESGRYETYGEDLYKLKNREKS
                     DFILGPTHEETFTAIVRDSVKSYKQLPLNLYQIQPKYRDEKRPRNGLLRTREFIMKDA
                     YSFHANYDSLDSVYDEYKAAYERIFTRSGLDFKAIIGDGGAMGGKDSQEFMAITSART
                     DLDRWVVLDKSVASFDEIPAEVQEEIKAELLKWIVSGEDTIAYSSESSYAANLEMATN
                     EYKPSNRVVAEEEVTRVATPDVKSIDEVAAFLNVPEEQTIKTLFYIADGELVAALLVG
                     NDQLNEVKLKNHLGADFFDVASEEEVANVVQAGFGSLGPVGLPENIKIIADRKVQDVR
                     NAVVGANEDGYHLTGVNPGRDFTSEYVDIREVREGEISPDGQGVLNFARGIEIGHIFK
                     LGTRYSASMGADVLDENGRAVPIIMGCYGIGVSRLLSAVMEQHARLFVNKTPKGEYRY
                     AWGINFPKELAPFDVHLITVNVKDEEAQALTEKLEASLMGAGYEVLTDDRNERVGVKF
                     SDSDLIGLPIRITVGKKAADGIVEVKIKATGDTIEVHADNVLETLEILSKK"
     gene            11746..13125
                     /gene="bglA"
                     /locus_tag="VQ865_001212"
     CDS             11746..13125
                     /gene="bglA"
                     /locus_tag="VQ865_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HET3135547.1"
                     /translation="MLRFPKDFVWGSSTSGPQTEGRVAGDGKGDNLWDYWFQVEPNRY
                     YNGIGSDKTSTFYENWERDIELLLETGHTAFRTSIQWSRIFPQGCGKVNPQGVDFYRK
                     VFEAIKAKGIRLLVNLYHFDLPFALQEDGDGWENKATVSAYEDYARFCFETYGDLVDQ
                     WITFNEPIVPVEFGYFYDAHYPHKVDAEAAVKVAYHTQLASSRAVKACHELLPDSKIG
                     IVLNLTPAYPRSQHPADVKAARIAALFQAQSFLDPSVLGTYPQELVEILHEHGLLPDA
                     TEEELELIRDNTVDFLGVNYYQPLRVMAPRFAKHPESPLLPEHFYEPYVMPGRKINSH
                     RGWEIYEQGIYDIAQNIKENYGNIEWMLTENGMGVEGEEKFRQDGMIQDDYRIDFVKG
                     HLRELHRAIEDGANCKGYLIWTFIDCWSWLNSYKNRYGLVELDLETQERRLKKSGHWF
                     KELSDNNGF"
     gene            13318..15126
                     /gene="glmS"
                     /locus_tag="VQ865_001213"
     CDS             13318..15126
                     /gene="glmS"
                     /locus_tag="VQ865_001213"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014621492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HET3135548.1"
                     /translation="MCGIVGVVGNTNATDILIQGLEKLEYRGYDSAGIFVLDGADNHL
                     VKAVGRIAELSAKTAGVEGTTGIGHTRWATHGKPTEDNAHPHRSETERFVLVHNGVIE
                     NYLEIKEEYLAGHHFKGQTDTEIAVHLIGKFAEEEGLSVLEAFKKALHIIRGSYAFAL
                     VDSQDPEVIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETNQYMEIHDQELVIVKADS
                     VEVQDYDGNRRERASYTAELDLSDIGKGTYPYYMLKEIDEQPTVMRKLIQAYTDEAGQ
                     VVVDPDIIKAVQDADRIYILAAGTSYHAGFASKKMLEELTDTPVELGISSEWGYGMPL
                     LSKKPLFIFISQSGETADSRQVLVKANEMGIPSLTVTNVPGSTLSREANYTMLLHAGP
                     EIAVASTKAYTAQIAALAFLAKAVGEANGNAKAQAFDLVHELSIVAQSIESTLSEKET
                     IEAKVRELLETTRNAFYIGRGQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTIALI
                     EEGTPVLALLSDPVLANHTRGNIQEVAARGAKVLTIAEENVAKDTDDIVLTTVHPYLS
                     PISMVVPTQLVAYFATLHRGLDVDKPRNLAKSVTVE"
     gene            complement(15264..15341)
                     /locus_tag="VQ865_001214"
                     /pseudo
     CDS             complement(15264..15341)
                     /locus_tag="VQ865_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002674100.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            15398..16447
                     /locus_tag="VQ865_001215"
     CDS             15398..16447
                     /locus_tag="VQ865_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000229779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HET3135549.1"
                     /translation="MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLD
                     VYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDAL
                     SNGRAEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTI
                     AGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYRE
                     IGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQ
                     YLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGT
                     QVAPKVRAYFAMKEA"
     gene            complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ865_001216"
     CDS             complement(16547..20317)
                     /gene="spuA"
                     /locus_tag="VQ865_001216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored pullulanase SpuA"
                     /protein_id="HET3135550.1"
                     /translation="MRKTPSHTEKKMVYSIRSLKNGTGSVLIGASLVLLAMATPTISS
                     DESTPTTNEPNNRNTTTLAQPLTDTAAGSGKNESDISSPRNANASLEKTEEKPATEPT
                     TSTSPVTTETKAEEPIEDNYFRIHVKKLPEENKDAQGLWTWDDVEKPSENWPNGALSF
                     KDAKKDDYGYYLDVKLKGEQAKKISFLINNTAGKNLTGDKSVEKLVPKMNEAWLDQDY
                     KVFSYEPQPAGTVRVNYYRTDGNYDKKSLWYWGDVKNPSSAQWPDGTDFTATGKYGRY
                     IDIPLNEAAREFGFLLLDESKQGDDVKIRKENYKFTDLKNHSQIFLKDDDESIYTNPY
                     YVHDIRMTGAQHVGTSSIESSFSTLVGAKKEDILKHSNITNHLGNKVTITDVAIDEAG
                     KKVTYSGDFSDTKHPYTVSYNSDQFTTKTSWRLKDETYSYDGKLGADLKEEGKQVDLT
                     LWSPSADKVSVVVYDKNDPDKVVGTVALEKGERGTWKQTLDSTNKLGITDFTGYYYQY
                     QIERQGKTVLALDPYAKSLAAWNSDDAKIDDAHKVAKAAFVDPAKLGPQDLTYGKIHN
                     FKTREDAVIYEAHVRDFTSDPAIAKDLTKPFGTFEAFIEKLDYLKDLGVTHIQLLPVL
                     SYYFVNELKNHERLSDYASSNSNYNWGYDPQNYFSLTGMYSSDPKNPEKRIAEFKNLI
                     NEIHKRGMGAILDVVYNHTAKVDIFEDLEPNYYHFMDADGTPRTSFGGGRLGTTHHMT
                     KRLLVDSIKYLVDTYKVDGFRFDMMGDHDAASIEEAYKAARALNPNLIMLGEGWRTYA
                     GDENMPTKAADQDWMKHTDTVAVFSDDIRNNLKSGYPNEGQPAFITGGKRDVNTIFKN
                     LIAQPTNFEADSPGDVIQYIAAHDNLTLFDIIAQSIKKDPSKAENYAEIHRRLRLGNL
                     MVLTAQGTPFIHSGQEYGRTKQFRDPAYKTPVAEDKVPNKSHLLRDKDGNPFDYPYFI
                     HDSYDSSDAVNKFDWTKATDGKAYPENVKSRDYMKGLIALRQSTDAFRLKSLQDIKDR
                     VHLITVPGQNGVEKEDVVIGYQITAPNGDIYAVFVNADEKAREFNLGTAFAHLRNAEV
                     LADENQAGSVGIANPKGLEWTEKGLKLNALTATVLRVSQNGTSHESTAEEKPDSTPSK
                     PEHQDPAPEARPDSTKPDAKVADAENKPSQATADSQAEQPAQEAQASSVKEAVQNESV
                     ENSSKKNIPVTPDKQAELPNTGIKNENKLLFAGISLLALLGLGFLLKNKKEN"
     gene            20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ865_001217"
     CDS             20734..21147
                     /gene="rpsL"
                     /locus_tag="VQ865_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HET3135551.1"
                     /translation="MPTINQLVRKPRKSKVEKSKSPALNVGYNSHKKVQTNVSSPQKR
                     GVATRVGTMTPKKPNSALRKFARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQGRSKYGTKRPKA"
     gene            21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ865_001218"
     CDS             21167..21637
                     /gene="rpsG"
                     /locus_tag="VQ865_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011285383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HET3135552.1"
                     /translation="MSRKNRAPKRDVLPDPLYNSQLVTRLINRVMLDGKRGTAASIVY
                     GAFEQIKEATGNDALEVFETAMENIMPVLEVRARRVGGSNYQVPVEVRPERRTTLGLR
                     WLVTIARLRGEHTMQDRLAKEILDAANNTGAAVKKREDTHRMAEANRAFAHFRW"
     gene            22062..24143
                     /gene="fusA"
                     /locus_tag="VQ865_001219"
     CDS             22062..24143
                     /gene="fusA"
                     /locus_tag="VQ865_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HET3135553.1"
                     /translation="MAREFSLEKTRNIGIMAHVDAGKTTTTERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWNNHRVNIIDTPGHVDFTIEVQRSLRVLDGA
                     VTVLDSQSGVEPQTETVWRQATEYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGSEDDFRGIIDLIKMKAEIYTNDLGTDILEEDIPAEYLDQAQEYREKLVEAV
                     AETDEELMMKYLEGEEITNEELKAGIRKATINVEFFPVLCGSAFKNKGVQLMLDAVID
                     YLPSPLDIPAIKGINPDTDAEETRPASDEEPFAALAFKIMTDPFVGRLTFFRVYSGVL
                     QSGSYVLNTSKGKRERIGRILQMHANSRQEIETVYSGDIAAAVGLKDTTTGDSLTDEK
                     AKIILESINVPEPVIQLMVEPKSKADQDKMGIALQKLAEEDPTFRVETNVETGETVIS
                     GMGELHLDVLVDRMRREFKVEANVGAPQVSYRETFRASTQARGFFKRQSGGKGQFGDV
                     WIEFTPNEEGKGFEFENAIVGGVVPREFIPAVEKGLVESMANGVLAGYPMVDVKAKLY
                     DGSYHDVDSSETAFKIAASLALKEAAKSAQPAILEPMMLVTITVPEENLGDVMGHVTA
                     RRGRVDGMEAHGNSQIVRAYVPLAEMFGYATVLRSASQGRGTFMMVFDHYEDVPKSVQ
                     EEIIKKNKGED"
     gene            24247..28638
                     /locus_tag="VQ865_001220"
     CDS             24247..28638
                     /locus_tag="VQ865_001220"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HET3135554.1"
                     /translation="MSNSFEILMNQLGIPVEMRQHPALTQADIERVVVHKISKVWEFH
                     FVFSNILPIEIFLELKKGLSEEFSKTGNKAVFEIKVLSQDFSNQLLQAYYREAFSEGP
                     CASQSFKSLYQNLQVRAEGNQLFIEGSEAIDKEHFKKNHLPNLAKQLEKFGFPTFNCQ
                     VEKNDVLTQEQEDAFHAENEQIVQAANEEALRAMEQLEQMAPPPAEEKPAFDFQTKKA
                     AAKPKLDKAEITPMIEVTTEENRLVFEGVVFDVEQKVTRTGRVLINFKMTDYTSSFSM
                     QKWVKNEEEAQKFDLIKKNSWLRVRGNVEMNNFTRDLTMNVQDVQEVVHYERKDLMPE
                     GERRVEFHAHTNMSTMDALPEVEEIVATAAKWGHKAVAITDHGNVQSFPHGYKAAKKA
                     GIQLIYGMEANIVEDRVPIVYNEVERDLSEATYVVFDVETTGLSAIYNDLIQVAASKM
                     YKGNVIAEFDEFINPGYPLSAFTTELTGITDDHVKNAKPLEQVLQEFQEFCKDTVLVA
                     HNATFDVGFMNANYERHGLPKISQPVIDTLEFARNLYPEYKRHGLGPLTKRFGVALEH
                     HHMANYDAEATGRLLFIFIKEVAEKHGVTDLARLNIDLISPDSYKKARIKHATIYVKN
                     QVGLKNIFKLVSLSNTKYFEGVPRIPRTVLDAHREGLILGSACSEGEVFDAVVSQGVD
                     AAVEVAKYYDFIEVMPPAIYAPLIAKEQVKDMEELQTIIKNLIEIGDRLGKPVLATGN
                     VHYIEPEEEIYREIIVRSLGQGAMINRTIGHGEHAQPAPLPKAHFRTTNEMLDEFAFL
                     GEELARKLVIENTNALAEIFEPVEVVKGDLYTPFIDKAEETVAELTYKKAFEIYGNPL
                     PDIVDLRIEKELTSILGNGFAVIYLASQMLVQRSNERGYLVGSRGSVGSSFVATMIGI
                     TEVNPLSPHYVCGQCQYSEFITDGSYGSGFDMPNKDCPNCGHKLSKNGQDIPFETFLG
                     FDGDKVPDIDLNFSGEDQPSAHLDVRDIFGEEYAFRAGTVGTVAAKTAYGFVKGYERD
                     YGKFYRDAEVERLAQGAAGVKRTTGQHPGGIVVIPNYMDVYDFTPVQYPADDVTAEWQ
                     TTHFNFHDIDENVLKLDVLGHDDPTMIRKLQDLSGIDPNEIPMDDEGVMALFSGTDVL
                     GVTPEQIGTPTGMLGIPEFGTNFVRGMVDETHPTTFAELLQLSGLSHGTDVWLGNAQD
                     LIKQGIADLSTVIGCRDDIMVYLMHAGLEPKMAFTIMERVRKGLWLKISEEERNDYIE
                     AMKANKVPEWYIESCGKIKYMFPKAHAAAYVMMALRVAYFKVHHPIYYYCAYFSIRAK
                     AFDIKTMGAGLEVIKRRMEEISEKRKNNEASNVEIDLYTTLEIVNEMWERGFKFGKLD
                     LYRSQATEFLIDGDTLIPPFVAMDGLGENVAKQLVRAREEGEFLSKTELRKRGGLSST
                     LVEKMDEMGILGNMPEDNQLSLFDELF"
     gene            28740..29003
                     /locus_tag="VQ865_001221"
     CDS             28740..29003
                     /locus_tag="VQ865_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HET3135555.1"
                     /translation="MSKMSISIRLDSEVKEQAQQVFSNLGMDMTTAINIFLRQAIQYQ
                     GLPFDVRLDENRKLLQALTDLDQNRNMSQSFESVSDLMEDLRA"
     gene            28996..29274
                     /locus_tag="VQ865_001222"
     CDS             28996..29274
                     /locus_tag="VQ865_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013904578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system YafQ family
                     toxin"
                     /protein_id="HET3135556.1"
                     /translation="MLKIRYHKQFKKDFKLAMKRGLKAELLEEVLNFLVQEKEHPARY
                     RDHSLTASKHFQGVRECHTQPDWLLVYKVDKSELILNLLRTGSHSDLF"
     gene            29295..29447
                     /locus_tag="VQ865_001223"
     CDS             29295..29447
                     /locus_tag="VQ865_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000776615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135557.1"
                     /translation="MKLRIFAEDKPAKKVFEYQLELADRTILLSTALLSGAIALAGIF
                     SALREK"
     gene            29469..30710
                     /locus_tag="VQ865_001224"
     CDS             29469..30710
                     /locus_tag="VQ865_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HET3135558.1"
                     /translation="MVLPNFKENLEKYAKLLVANGINVQPGHTLALSIDVEQRELAHL
                     IVKEAYALGAHEVIVQWTDDVINREKFLHAPMERLDNVPEYKIAEMNYLLENKASRLG
                     VRSSDPGALNGVDADKLSASAKAMGLAMKPMRIATQSNKVSWTVAAAAGLEWAKKVFP
                     NAASDEEAVDFLWDQIFKTCRVYEADPVKAWEEHAAILKSKADMLNKEQFSALHYTAP
                     GTDLTLGLPKNHVWESAGAVNAQGEEFLPNMPTEEVFTAPDFRRADGYVTSTKPLSYN
                     GNIIEGIKVTFKDGQIVDITAEKGDQVMKDLVFENAGARALGECALVPDPSPISQSGI
                     TFFNTLFDENASNHLAIGAAYATSVVDGAEMSEEELEAAGLNRSDVHVDFMIGSNQMD
                     IDGIREDGTRVPLFRNGNWAN"
     gene            30720..30950
                     /locus_tag="VQ865_001225"
     CDS             30720..30950
                     /locus_tag="VQ865_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000901571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HET3135559.1"
                     /translation="MLGSMFVGLLVGFLAGAMTNRGERMGCFGKMFLGWIGAFLGHLL
                     FGTWGPVLSGTAIIPAILGAMIVLAIFWRRGS"
BASE COUNT         8794 a         5924 c         7247 g         8997 t
ORIGIN      
        1 gttcttcata aatcaaaaag cgacataggt agtcggctat ttattgtgaa tacattaatt
       61 agcattccag ttttatcttc ggtctaaaat aagtattttg tgctatacga gataagcttc
      121 ttgacttact ccttgattta ctgcataaca atgggataaa aagtgggaga tagagcaatt
      181 catagtcatc aaaattaatg agatacagta tacagttttt cctttaaaca catttcaaat
      241 tccctcaaaa atggtataat agtaacatca caaaattgga gagagaccat gagtttttac
      301 aatcataaag aaattgagcc taagtggcag ggctactggg cagaacatca tacatttaag
      361 acaggaacag atgcatcaaa acctaagttt tatgcgcttg atatgttccc ttatccgtct
      421 ggagctggtc tgcacgtagg acacccagaa ggttatactg caaccgatat cctcagtcgt
      481 tacaaacgtg cgcaaggcta caatgtcctt cacccaatgg gttgggatgc ttttggtttg
      541 cctgcagagc aatacgctat ggatactggt aatgacccag cagaatttac agcggaaaac
      601 attgccaact tcaaacgtca aatcaatgcg cttggatttt cttatgactg ggatcgtgaa
      661 gtcaacacaa cagatccaaa ctactacaag tggactcaat ggattttcac caagctttac
      721 gaaaaaggct tggcctatga agctgaagtg ccagtaaact gggttgagga attgggaact
      781 gccattgcca atgaagaagt gcttcctgac ggaacttctg aacgtggagg ctatccagtt
      841 gtccgcaaac caatgcgcca atggatgctc aaaatcacgg cttacgcaga gcgcttgctc
      901 aatgacttag atgaactaga ttggtcagag tctatcaagg atatgcaacg caactggatt
      961 ggtaaatcaa ctggtgccaa tgtaactttc aaagtaaaag gaacagacaa ggaatttaca
     1021 gtctttacta ctcgtccgga cacacttttc ggtgcgactt tcactgtttt ggctcctgaa
     1081 catgaattag tagatgccat cacaagcaca gagcaagcag aagcagtagc agactacaaa
     1141 caccaagcca gccttaagtc agacttggct cgtaccgacc ttgccaaaga aaaaactggt
     1201 gtatggactg gtgcttatgc catcaatcct gtcaatggta aggaaattcc aatctggatt
     1261 gcggattacg ttcttgctag ctatggtaca ggtgcggtaa tggctgtgcc tgcccacgat
     1321 caacgtgact gggaatttgc caaacaattt gaccttccaa tcgtcgaagt acttgaaggt
     1381 ggaaatgttg aagaagctgc ctacacagaa gatggccttc acgttaattc agacttccta
     1441 gatggactca acaaagaaga cgctattgcc aagattgtgg cttgcttgga agaaaaaggc
     1501 tgtggacaag agaaggtaac ctaccgtctc cgcgactggc tctttagccg tcaacgttac
     1561 tggggtgagc caatcccaat cattcattgg gaagatggaa cttcaacagc tgtccctgaa
     1621 agtgaattgc cacttgtctt gcctgtaacc aaggatatcc gtccctcagg tactggtgaa
     1681 agtccactag ctaacttgac agactggctt gaagtgactc gtgaagatgg tgtcaaaggt
     1741 cgtcgtgaaa caaatactat gccacaatgg gcaggttcaa gctggtacta cctccgctat
     1801 attgacccac acaatactga gaaattggct gacgaggatc tgctcaaaca atggttgcca
     1861 gtagatatct acgtgggtgg tgcggaacat gctgtacttc acttgcttta cgctcgtttc
     1921 tggcataaat tcctctatga cctcggtgtt gttccaacta aggaaccatt ccaaaaactc
     1981 tttaaccaag ggatgatttt gggaacaagc tatcgtgacc accgtggggc tcttgtggcg
     2041 actgacaagg ttgaaaaacg tgatggttct ttcttccatg tggaaacagg ggaagagttg
     2101 gagcaagcgc cagccaagat gtctaaatcg ctcaagaacg ttgtcaaccc agacgatgtg
     2161 gtggaacaat acggtgccga tacccttcgt gtttatgaaa tgttcatggg cccacttgat
     2221 gcttcaatcg cttggtcaga agaaggtctg gaaggaagtc gtaaattcct tgaccgtgtt
     2281 tatcgtttga ttacaagtaa ggaaattatt gcggaaaaca atggtgctct tgacaaggtt
     2341 tataacgaaa ccgttaaagc tgtcacagag caaatcgaat cattgaaatt caacacagct
     2401 attgcccaac ttatggtctt tgtcaacgcc gctaacaagg aagacaagct ctatgtggac
     2461 tatgccaaag gatttatcca attgattgcg ccatttgcac ctcacttggc agaagaactt
     2521 tggcaaactg ttgcagcaac aggtgaatca atctcttacg tagcttggcc aacatgggat
     2581 gaaagtaaat tggttgaaga cgaaatcgaa atcgtcgtcc aaatcaaagg taaagtccgt
     2641 gccaaactca tggttgctaa agacctgtca cgtgaagaat tgcaagaaat tgctcttgct
     2701 gatgaaaaag tcaaggtaga aattgacggt aaggaaatcg tgaaagtgat tagtgtacca
     2761 aataaattgg ttaatattgt tgtaaaataa ccaatttatt tgctgatttc caacctcaaa
     2821 cagtttccca aactgtttga gccaactaaa ctcgttaata tcgttgtgaa ataaggtagg
     2881 aatccttcag agtagaatct ggaggatttt ttgaatcttc ttatgaaagt atggtatact
     2941 atgggcaact ataaagtttg aaaagtgaaa aaaggagaaa gctatgccag taaatgaata
     3001 tggtcaaatg attggggagt caatggaagg ttatacacca ggtgaactgc cttctattga
     3061 tttcttagaa gggcgttatg ctaggataga ggctctttca gtggaaaagc atgcggagga
     3121 tttgctagct gtttatgggc ctgatacgcc tcaggagatg tggacctacc tttttcagga
     3181 gccagtagca gatatggggg agctggttag ccttttacat cagatgatgg ctcgtaagga
     3241 ccgtttttac tatgcaatca tagacaaggc gactggtaag gctttgggat ctttttctct
     3301 catgcgcatt gaccagaata accgagtaat agaagtcgga gcagtcactt tttctccaga
     3361 gctaaggggt acacggatag gaactgaagc tcagtatctc ctagctcgct atgtttttga
     3421 ggagctaaac tatcgtcgct acgagtggaa atgcgatgcc ttaaatctgc catccagacg
     3481 agctgcggag cgtttgagct ttatttatga aggaaccttc cgtcaggcag tggtttataa
     3541 gggacgtacg agagatacgg attggttgtc tatgattgat aaggactggc ctcaagtcaa
     3601 agatcgtttg gaaacatggt tgcgtcctga aaattttgat aaaaatggac agcagtacaa
     3661 gagcttgaga gaactttaag aggtgttgag atgattacta ttaaaaagca agaaattgtc
     3721 aagctagagg atgttttaca tctctatcag gctgtcggtt ggacaaatta tacccatcaa
     3781 ccagagatgc tggagcaggc cttatctcat tcattagtaa tttatctggc acttgatggt
     3841 gatgctgtgg tgggcttgat tcgtttggtt ggagatggat tctcatcagt attggttcag
     3901 gatttaatcg ttttaccaat ctatcagcgt caaggaattg gtagtgcctt gatgaaagag
     3961 gctttagagg attacaaaga tgcctatcaa gtccagctgg tgacagaaga gacagaaaga
     4021 accttgggct tctatcgttc tatgggcttt gaaatcttat ccacctataa ttgtataggg
     4081 atgacttgga tgaatcgtaa aaaataacaa aacttgtttt ttcttaagca aaatttaagg
     4141 atggtctagt attatatagt cattaaataa agacctccta actttattta ataaaatcct
     4201 aaactttttt catcacaatc tcctaatgaa gccacccaat caggtggctt ttttgcgtgg
     4261 tgaggtgctg gtgatagaaa ttttttgcaa aatagtaaaa ttttagaaaa gttaagctag
     4321 ttttaagttt cgtcttgtat catgtagtta ttaaataaag acctcctaac tttatttaat
     4381 aaaatcctaa acttttcttt ttcataataa tctcccttaa ctccacccaa tcaggtggag
     4441 ttttttagct ctatttcagg cttttgggga ctattctaaa aataattttt cgatattttt
     4501 cggtattttt cggattttgg tcggggaatt ggcggggact tttttagcga atataactaa
     4561 gaaataggtc tgtggtcgct tcagctagtt caaactcaat ttgattgtaa gtgactgtta
     4621 attgaagaac tggaactact gtaataatga ttttgcttgt ctagtagtgg cgtattaaat
     4681 gaaaagtgac atgtaagatt gtctcttcgt ttacgaaatc aaaatttcta tgaaattgat
     4741 agaatcccta acgttctctt aatcttaacc gtcttgtcgt acagcggttg aagaaaatgt
     4801 aaacctttga caaaattcgt gaactatggg ataataaaaa ggaattgagt actagttcta
     4861 tatcataggc tagaaaagac cccaagctca cgaccaaata agcttgaggt cttttttgac
     4921 actatttgtc cttgtttagc catttatcga ctatacgaag aacgacaccg accacaattg
     4981 gtccgatgat agttttgagt actaattcca tcatgggcta tctcacctcc tttcgtaggc
     5041 ggtgtagaag tgtcgtagaa tattatacca cataagtgct aaacttagga gtcacccaat
     5101 caggtggctt ttttgtttgt ggcttggttt tttgatataa tagagccatg agtagaattt
     5161 tagataatga gataatgggg gatgaggagt tagtagaacg cacgctccgt cctcagtatt
     5221 tacgtgaata tatcggacag gataaggtca aggaccagct acaaatcttt attgaagctg
     5281 ccaaaatgcg ggatgaagcg ctggatcatg tgctcttatt tgggcctcca ggtctcggga
     5341 aaacgaccat ggcctttgtt attgccaacg aactgggagt caatcttaag cagacgtcgg
     5401 gtccagtcat tgaaaaagcc ggagatctgg tagctatttt gaatgagtta gagcctgggg
     5461 atgtactttt tattgatgag atccatcgtt tgccaatgtc agtggaagag gtgctttata
     5521 gtgctatgga ggacttctac atagatatta tgattggggc tggtgagggt agtcgtagtg
     5581 ttcatttgga gttaccacct tttaccttga ttggtgcgac gactcgggct ggtatgctct
     5641 ccaatccgct acgggcacgt tttgggatta caggccatat ggagtattat gcccatgctg
     5701 acttgacaga aattgtcgag cggacggcag atatttttga gatggaaatc actcatgagg
     5761 cagcatctga gttggcccta cgtagtcgtg ggacccctcg tattgccaat cgtctcctca
     5821 agcgcgtgcg cgattttgcc cagataatgg ggaatggggt aattgatgat attattaccg
     5881 ataaggcttt gactatgctg gatgttgacc atgaaggttt ggactatgtg gatcaaaaaa
     5941 tccttcgtac catgattgag atgtacagtg gaggacctgt tggtctagga actctttctg
     6001 tgaatatcgc cgaagagcgt gagacagttg aagatatgta tgagccttac ttgattcaaa
     6061 aaggttttat catgcggaca cggtctggac gggtggcgac tgctaaggca tatgagcact
     6121 taggttatga atacagtgaa aaataagcaa gaaatcttag aggcttttag agaaaatcca
     6181 gatatgatgg ccattctgac gatcatccga gaccttggtc tgaaagactc gtggttggca
     6241 gcaggttctg tcagaaattt catttggaat cttttgtcag acaaatcccc ttttgatcat
     6301 gaaacagata tagatgtgat tttctttgat ccagattttt cttatgagga aaccttatta
     6361 ctggagaaaa agctgcgaga ggattttcct cagtaccagt gggaattgaa aaatcaggtc
     6421 tatatgcatc agcacagtcc tcacactgct tcctatacca gttctcgtga tgctatgagt
     6481 aagtatccag aacggtgtac gacagttgga ctgcgcttga atgaagaatc agattttgaa
     6541 ctctatgcac cttatggttt ggaggatatt ttgaattttc aagttcgtcc aactcctcat
     6601 ttcttagaaa atgaagaccg aatggaactc tatcaaacac gtttatccaa gaaaaattgg
     6661 caggagaaat ggaaaaattt gatttttaaa aatacttaag gaaactttaa gctagggagt
     6721 gtacactaag ttcataagtt aagaagacct taacttaaac tcctaaaact ttttcataat
     6781 aatctcccta taaaaataaa gtcgcccaat caggcggctt atttttttga aaaatgggct
     6841 tggtgcctga gaataaatag cttagtgata gaagaaaatg gggaaatatg gtataataaa
     6901 acgatagatt tttgaatagg aataagatca tgtttggatt ttttaagaaa gataaggctg
     6961 tggaagtaga ggttccgaca caggttcctg ctcatatcgg catcatcatg gatggcaatg
     7021 gccgttgggc taaaaaacgt atgcaaccgc gagtttttgg acataaggcg ggcatggaag
     7081 cattgcaaac cgtgaccaag gcagccaaca aactgggcgt caaggttatt acggtctatg
     7141 ctttttctac ggaaaactgg acccgtccag atcaggaagt caagtttatc atgaacttgc
     7201 cagtagagtt ttatgataat tatgtcccgg aactacatgc gaataatgtt aagattcaaa
     7261 tgattgggga gacagaccgc ctgcctaagc aaacctttga agctttaacc aaggctgagg
     7321 aattgactaa gaacaacaca ggattgattc ttaattttgc tcttaactat ggtggacgtg
     7381 ctgagattac acaggcgctt aagttgattt cccaggatgt tttagatgcc aaaatcaacc
     7441 caggtgacat cacagaggaa ttgattggta actatctctt tactcagcat ttgcctaagg
     7501 acttacgaga cccagacttg attatccgta ctagtggaga attacgtttg agcaatttcc
     7561 ttccatggca gggagcctat agtgagcttt attttacgga caccttatgg cctgattttg
     7621 acgaagcggc cttgcaggaa gctattcttg cctataatcg tcgtcatcgc cgatttggag
     7681 gagtttagga ggaaatatga cccaggattt acagaaaaga accttgtttg cagggattgc
     7741 cctggctatt ttcctaccaa ttttaatgat tgggggcctc ttgcttcaga tagcaatcgg
     7801 aatcatagcc atgctagcca tgcatgaact tttgaagatg agaggtctag agaccatgac
     7861 gatggagggc ctcttgaccc tctttgcaac ctttgcattg accattccct tggagaatta
     7921 cctgactttt ttgccagttg atgggaatgt ggttgcctat agtgttttga tttcaatcat
     7981 gttaggaacg accgttttta gcaagtctta tacgattgag gatgcggttt tccctcttgc
     8041 tatgagcttc tacgtgggct ttggatttaa tgctttacta gatgctcgtg ttgcaggttt
     8101 ggacaaggct ctcttagcct tgtgtatcgt ctgggcgaca gacagtggtg cctatcttgt
     8161 tgggatgaac tatgggaaac gaaagttagc accaagggta tcgcctaata aaacccttga
     8221 gggtgccttg ggtggtattt taggagcaat tttagtaacc attatcttta tgatagttga
     8281 cagtacagtt gctcttccat atggaattta caagatgtca gtctttgcta ttttctttag
     8341 cattgctgga caatttggtg atttactaga aagttcgatc aaacgtcatt ttggtgttaa
     8401 ggattctggg aaatttatcc ctggacatgg tggtgttttg gatcgtttcg atagtatgtt
     8461 gcttgtattt ccaatcatgc acttatttgg actcttttaa tcaaaagacg gaggaaacgc
     8521 tatgctcgga attttaacct ttattctggt tttcgggatt attgtagtgg tgcacgagtt
     8581 cgggcacttc tactttgcca agaaatcagg gattttagta cgtgaatttg ccatcggtat
     8641 gggacctaaa atttttgctc acattggtaa ggatggaacg gcctatacca ttcgaatctt
     8701 gcctctgggt ggctatgtcc gcatggccgg ttggggtgat gatacaactg aaatcaagac
     8761 aggaacgcct gttagtttga cacttgctga tgatggtaag gttaaacgca tcaatctctc
     8821 aggtaaaaaa ttggatcaaa cagccctccc tatgcaggtg acccagtttg attttgaaga
     8881 caagctcttt atcaaaggat tggttctgga agaagaaaaa acatttgcag tggatcacga
     8941 tgcaacggtt gtggaagcag atggtactga ggttcggatt gcacctttag atgttcaata
     9001 tcaaaatgcg actatctggg gcaaactgat taccaatttt gcaggtccta tgaacaattt
     9061 tatcttaggt gtcgttgttt tttgggtttt aatctttatg cagggtggtg tcagagatgt
     9121 tgataccaat cagttccata tcatgcccca aggtgccttg gccaaggtag gagtaccaga
     9181 aacggcacaa attaccaaga ttggctcaca tgaggttagc aactgggaaa gcttgatcca
     9241 agctgtggaa acagaaacca aagataagac ggcaccgact ttggatgtga ctatttctga
     9301 aaaggggagt gacaaacaag tcactgttac acccgaagat agtcaaggtc gttaccttct
     9361 aggtgttcaa ccgggggtta agtcagattt tctatccatg tttgtaggtg gttttacaac
     9421 tgctgctgac tcagctctcc gaattctctc agctctgaaa aatctgattt tccaaccgga
     9481 tttgaacaag ttgggtggac ctgttgctat ctttaaggca agtagtgatg ctgctaaaaa
     9541 tggaattgaa aatatcttgt acttcttggc aatgatttcc atcaatattg ggatttttaa
     9601 tcttattccg attccagcct tggatggtgg taagattgtg ctcaatatcc tagaagccat
     9661 ccgccgcaaa ccattgaaac aagaaattga aacctatgtc accttggccg gagtggtcat
     9721 catggttgtc ttgatgattg ctgtgacttg gaatgacatt atgcgactct tttttagata
     9781 atcgaggaat attatgaaac aaagtaaaat acctatccca acgcttcgcg aaatgccaag
     9841 cgatgctcaa gttatcagcc atgctcttat gttgcgtgct ggttatgttc gccaagtttc
     9901 agcaggtgtt tattcttatc taccacttgc caaccgtgtg attgaaaaag ctaaaaacat
     9961 catgcgccaa gaattcgaaa agattggtgc tgttgagatg ttggctcctg cccttcttag
    10021 tgcagaattg tggcgtgaat caggtcgtta cgaaacctat ggtgaagacc tttacaaact
    10081 aaaaaaccgt gaaaaatcag actttatctt aggtccaact cacgaagaaa cctttacagc
    10141 tattgtccgt gattctgtta aatcttacaa gcaattgcca ctcaaccttt atcaaattca
    10201 gcccaagtat cgtgatgaaa aacgcccacg taatggactt cttcgtacac gtgagtttat
    10261 catgaaggat gcttatagtt tccacgctaa ctatgatagt ttggatagtg tttatgatga
    10321 gtacaaagca gcctatgagc gtattttcac tcgtagtggt ttagacttca aggctattat
    10381 tggtgacggt ggagccatgg gtggtaagga tagccaagaa tttatggcca ttacatctgc
    10441 tcgtacagac cttgaccgct gggttgtctt ggacaagtca gttgcctcat ttgacgaaat
    10501 tcctgcagaa gtgcaagaag aaatcaaggc agaattgctc aaatggatag tctctggtga
    10561 agataccatt gcttactcaa gtgagtctag ctatgcagct aacttagaaa tggcaacaaa
    10621 cgagtacaaa ccaagcaacc gtgttgtcgc tgaagaagaa gttactcgtg ttgcaacgcc
    10681 agatgttaaa tcaattgatg aagttgcagc tttcctcaat gttccagaag aacaaacgat
    10741 taaaaccctc ttctacattg cagatggtga gcttgttgca gcccttctag ttggaaatga
    10801 ccaactcaac gaagtcaagt tgaaaaacca cttaggagca gatttctttg acgttgctag
    10861 cgaagaagaa gtggcgaatg ttgttcaagc aggatttggt tcacttggac cagttggttt
    10921 gccagagaat attaaaatta ttgcagatcg taaggtgcaa gatgttcgca atgcagttgt
    10981 cggtgctaac gaagatggct accacttgac tggtgtgaac ccaggccgtg attttacttc
    11041 agaatatgtg gatatccgtg aagttcgtga gggtgaaatt tccccagatg gacaaggtgt
    11101 ccttaatttt gcgcgtggta ttgagatcgg tcatattttc aaactcggaa ctcgctattc
    11161 agcaagcatg ggagcagatg tcttggatga aaatggtcgt gctgtgccaa tcatcatggg
    11221 atgttacggt atcggtgtca gccgtcttct ttcagcagtg atggagcaac acgctcgcct
    11281 ctttgttaac aaaacgccaa aaggtgaata ccgttacgct tggggaatca atttccctaa
    11341 agaattggca ccatttgatg tgcatttgat tactgtcaat gtcaaggatg aagaagcgca
    11401 agccttgaca gaaaaacttg aagcaagctt gatgggagct ggttatgaag tcttgacaga
    11461 tgaccgtaac gaacgtgtcg gtgttaaatt tagcgatagt gacttgattg gtcttccaat
    11521 ccgtatcact gttggtaaaa aagcggccga tggcattgta gaagttaaga tcaaggcaac
    11581 tggtgacacc attgaggttc atgcagataa cgtgcttgaa acgcttgaaa tcctaagcaa
    11641 gaaataaaaa ctataatcag aagaaaaaca aggaaaaaat gtaactagtt tttaccttgt
    11701 tttttctgta taatgggaga aatgagtaga taaagaggta aatgtatgct aagatttcca
    11761 aaggattttg tctggggatc ctctacttct ggaccgcaga cagaaggacg tgtagctggt
    11821 gacggtaagg gagacaatct ctgggattac tggttccaag tggagccaaa tcgttactat
    11881 aatgggattg gttcagataa gacatcgact ttttatgaaa attgggagcg ggatattgag
    11941 cttttgttag agactggtca cacagccttt cggacttcta ttcagtggtc acggattttt
    12001 ccacaaggct gtggaaaagt caaccctcaa ggtgtggatt tttatcgtaa ggtctttgag
    12061 gctattaagg ctaaaggaat tcgtctgtta gtcaatctct atcattttga tttacctttt
    12121 gcccttcaag aggatggtga tggttgggaa aataaggcga cagtctcagc ctatgaagac
    12181 tatgctcgtt tttgttttga gacttatgga gatttagtgg atcaatggat tacctttaac
    12241 gagcccatcg ttcctgtaga atttggttat ttttatgatg cccattatcc acataaggtg
    12301 gatgcagagg cagctgttaa ggtagcctat catacacaat tggccagcag ccgggctgtt
    12361 aaggcttgcc atgaactttt gcctgattcc aagattggga ttgtcctcaa cttgacaccg
    12421 gcttatccac gtagccagca tcctgctgat gtcaaggcag ctcgtattgc ggcccttttt
    12481 caggcccaat ctttcttaga tccatctgtc ttggggactt atccacagga gttggtagaa
    12541 atcttgcatg aacacggtct tttacctgat gctacagagg aagagttgga actcattcgt
    12601 gataatacgg tggacttcct tggtgtgaac tactatcaac ctttgcgtgt tatggctcct
    12661 cgatttgcta agcatccaga gagtccactc ttaccagaac atttttacga gccttatgtg
    12721 atgcctggac gtaaaatcaa ttctcaccgt ggttgggaga tttatgagca agggatttat
    12781 gacatcgccc aaaatatcaa ggaaaattat ggcaatattg agtggatgtt gactgagaat
    12841 ggtatgggtg ttgaagggga agaaaaattc cgtcaagatg gaatgattca agatgattac
    12901 cgtattgact ttgtaaaagg tcatcttcgt gaacttcacc gtgccattga agatggtgcc
    12961 aactgtaagg gctacttgat ttggaccttt attgactgct ggtcatggct caacagctat
    13021 aaaaatcgct atggtttggt cgaattagac ttggaaacgc aagaacgtcg tctgaagaaa
    13081 tcaggccact ggttcaaaga attaagcgat aataatggat tttaaaaagg actctgactg
    13141 attatcccaa tcggtcagag tttttatgct tacaggagct taatttgaac tataccaatt
    13201 tttactcttg acaagtgaaa gaaacaagta tatactgttt ttgctgattc tataaaagat
    13261 gaattagact ataccaattt taaggagaaa gcacagcttg cctgtgtcgt atatactatg
    13321 tgtggaattg ttggtgttgt tggaaacaca aatgcaactg atattttgat tcaagggctt
    13381 gaaaagcttg aataccgtgg ctatgattct gcgggaattt ttgtcctaga tggtgctgat
    13441 aaccatttag tgaaggcggt tggtcgtatt gcagaattgt ctgccaagac agctggtgtt
    13501 gagggaacaa ctggtatcgg acatactcgt tgggctactc acggaaaacc aactgaggac
    13561 aatgctcacc cacaccgctc tgagacagaa cgctttgtct tggtgcataa tggggtgatt
    13621 gagaactatc ttgaaatcaa ggaagaatac cttgcaggtc accacttcaa ggggcagaca
    13681 gatactgaaa tagccgttca tttgattgga aaatttgcgg aagaagaagg gctctcagtt
    13741 cttgaagcct tcaaaaaagc ccttcacatc atccgtggtt cttatgcctt tgccttggtt
    13801 gactcacaag atcctgaagt catctacgta gctaaaaata aatcaccact tttgattggt
    13861 cttggagaag gctataacat ggtctgctca gacgccatgg ctatgattcg tgaaactaac
    13921 caatacatgg aaatccatga ccaagagttg gtaatcgtca aggctgatag tgtggaagtt
    13981 caagactatg atggaaatcg tcgtgagcgt gctagctaca ctgctgaact tgacttgtca
    14041 gatatcggta agggaactta cccttactac atgctcaagg aaattgacga gcaaccaact
    14101 gttatgcgga aactcatcca agcctacaca gatgaggctg gtcaagttgt cgtagaccca
    14161 gatatcatta aggctgttca agacgcagac cgcatctaca tccttgcagc tggaacatct
    14221 taccatgcag gatttgcttc taagaaaatg ttggaagaat tgacagatac accagttgaa
    14281 cttggaatct catctgagtg gggctacggt atgccacttc tcagcaagaa accactcttc
    14341 atctttatca gccaatctgg tgaaacagcg gatagtcgtc aagttttggt caaggctaat
    14401 gaaatgggaa ttccaagctt aacagtgaca aacgttccag gttcaaccct ctcacgtgaa
    14461 gccaactata ccatgctcct tcacgcaggt cctgaaattg ccgtggcatc aactaaagcc
    14521 tatacagcgc aaatcgcagc ccttgccttc cttgcaaaag cagtcggaga agcaaatggt
    14581 aatgctaaag cgcaagcctt tgacctggtt catgaattgt caatcgtagc tcagtctatc
    14641 gaatcaactc tttcagagaa agaaaccatt gaagccaagg ttcgtgaact tcttgaaaca
    14701 actcgtaacg ccttttacat cggacgtggt caagattact acgtagccat ggaagcaagt
    14761 ctcaaactca aagagatttc ttatatccag tgtgaaggct ttgctgcagg agaactcaag
    14821 cacggaacca ttgccttgat tgaagaagga acgcctgttt tggctctctt gtcagatcca
    14881 gttcttgcca atcatactcg tggaaatatc caagaggtcg cagcccgtgg tgccaaagtc
    14941 ctcactatcg cagaagagaa tgtagccaaa gataccgacg atatcgtcct tacgaccgta
    15001 catccatacc tctcaccaat ttcaatggtc gtaccaacgc aattagtcgc ttactttgca
    15061 accctccacc gtggcctcga tgtggacaaa ccacgtaacc ttgccaagtc agtaacggta
    15121 gaataagcta aaaaagtcta gttatctagg cctttttctt gtgagcaaat tggttgcttg
    15181 tactcaagat tcgtgttata ctcttcgaaa atctcttcaa accacgtcaa cgtcgccttg
    15241 ccgtaggtat ggttactgac ttcgtcagtt ctatccacaa cctcaaaaca ctgttttgag
    15301 cagcctgcag ctagcttcct agtttgctct ttgattttca ttgagtatta gaataatttt
    15361 tcaaattgaa gtacagagat agataaggag aatcacaatg gtagaattgg gaatttcaac
    15421 atttggggaa ataacggagc ttgaagggac tggacaaact tacagtcatg ctgaacgcat
    15481 tcgccagttg gtggcagaga ttgagctggc tgacaaggtt ggtttggatg tatatgggat
    15541 tggtgagcac catcgggcgg attttgcagt atcagcccca gagattgttc tggccgctgg
    15601 ggcagtcaat accaagaaaa tccgtttgac cagtgcagtc agcattctgt caagcatgga
    15661 cccgattcgt ttgttccaac agtatgccac tatcgatgct ttgtcaaatg gacgagcgga
    15721 gattatggct ggaaggggct ctttcacgga atctttccct ctgtttggtt atgacttgaa
    15781 agactacgac tctctttttg atgagaaatt agacttgctt cagttagtca atgaaaagac
    15841 caagttagac tggcaaggtc gattgactca aacgattgct ggtaaagaag tttatcctcg
    15901 tccagttcag gacaaattgc ccttgtggat agctacaggt ggtcatgtcg aatcaacagt
    15961 gaagattgct caggctggtc taccgattgt atatgctatt attggtggta atccacgtta
    16021 ttttaaaaag ttgattcagg cttatcgtga gattggaagc gaagcgggtc atgctgacaa
    16081 agacttgaaa gtgggagccc attcttgggg gtggattgcg gaagatggtg agcaggcggt
    16141 gaaagattat ttccatccga ctaagcaagt ggtggatgct atttccaaag accgtccgca
    16201 ctggcaggaa ttgcgttatg agcaatattt ggagcaggta gggccaaatg gcgccatgtt
    16261 tgttggcaat ccagatcagg tggccgaaaa attgattcgc atgatagagg atttaggatt
    16321 ggaccgcttc atgcttcatc taccgcttgg ttctatgcct catgaccagg ttctgagagc
    16381 tattgaactc ttcggaacac aagttgcacc caaagtacga gcttattttg ctatgaaaga
    16441 ggcttaataa aaaatcctaa tcaagtttat taggacaaca aatattgtac gaaaattaat
    16501 cccccgagct ataatgcttg ggggattttt ctataggagg gctagtttag ttctcttttt
    16561 tattttttag taagaaaccg agaccaagga gcgcaaggag gctgattcct gcaaatagga
    16621 gtttgttttc gtttttgatt cctgtatttg gaagttcagc ttgtttatct ggggttacag
    16681 gtatattttt cttgctagag ttttctaccg attcgttttg aaccgcttct tttacagatg
    16741 atgcttgtgc ttcttgtgct ggttgttcag cttgtgaatc agctgtagct tggctaggtt
    16801 tattttccgc atcagctact ttggcatctg gtttagtaga atcaggtcta gcttctggag
    16861 ctgggtcttg atgttcaggc ttggaagggg ttgagtctgg tttctcttct gcagttgact
    16921 catggctagt tccattttga gagactcgaa gaacagtagc tgtaagggca ttcaatttca
    16981 agcctttttc agtccattca agtcctttcg ggttggcaat tccgactgat cctgcttggt
    17041 tttcatctgc caaaacttcc gcatttctta gatgtgcaaa ggcagttccc aaattaaatt
    17101 cgcgagcttt ttcatccgca ttgacaaaga ctgcgtagat atcgccgttt ggagcagtga
    17161 tttggtagcc aatcactaca tcctcttttt ccacaccatt ttggcctggg acagtgatga
    17221 ggtggacacg gtctttgata tcttggagac tcttaagtcg gaaggcatct gtagattgac
    17281 gaagggcaat caaacctttc atatagtcac ggctcttgac attttcagga taagctttac
    17341 catctgtagc cttagtccag tcaaacttgt tgactgcgtc gctagaatcg taagaatcat
    17401 ggatgaagta aggatagtca aatgggttgc cgtccttatc acgcaacaag tgagatttgt
    17461 ttggaacctt atcctctgct actggagtct tgtaggctgg gtcacggaat tgtttagtac
    17521 gtccatattc ctgaccggag tggataaatg gagttccttg agctgtcaag accatgagat
    17581 ttccaagtcg taaacgacgg tggatttcag catagttctc agccttgctt gggtcttttt
    17641 tgatagactg ggcaatgatg tcaaagaggg tcaagttatc atgggctgcg atgtattgga
    17701 tgacatctcc agggctgtca gcttcaaagt tagttggctg agcaatgaga tttttaaaga
    17761 tagtgttaac atcacgcttg ccacctgtga taaaggcagg ttgaccttcg tttggataac
    17821 cagatttgag gttgttacgg atgtcatctg aaaagacagc gacagtatcg gtatgtttca
    17881 tccaatcttg gtcagcagct ttagtaggca tgttttcatc accggcatag gttctccaac
    17941 cttcgcctaa catgattaga tttggattga gggcgcgtgc agccttgtaa gcttcttcga
    18001 tagaagcggc gtcatggtct cccatcatat cgaaacggaa tccatccact ttgtaggtat
    18061 caactaggta tttgatagag tcaactagga ggcgtttggt catatggtgg gttgtcccca
    18121 agcgtccacc accaaagcta gttcgaggtg tgccatcggc atccataaag tggtagtagt
    18181 ttggctctag gtcttcaaag atatcgactt tggctgtgtg gttataaacg acatctagga
    18241 tagctcccat accacgtttg tggatttcgt tgatgaggtt tttaaattct gcgattcgtt
    18301 tttctggatt cttaggatcg cttgagtaca taccagtcaa ggagaagtag ttttgagggt
    18361 catatcccca gttgtagttg ctgttgcttg aagcatagtc agacaagcgt tcatggtttt
    18421 tcaattcatt gacaaagtag taagacaaga ctggaaggag ctggatatgg gttacaccca
    18481 agtctttgag atagtctagt ttttcaatga aggcttcaaa agtcccaaat ggtttggtca
    18541 agtcttttgc aatggcagga tctgaagtga agtcacgcac atgagcttcg tagataacgg
    18601 cgtcttcacg agtcttgaaa ttgtgaatct taccataagt caagtcttga ggtccgagtt
    18661 tagctggatc tacaaaggcg gctttagcca ctttatgggc atcgtcaatc ttggcatcgt
    18721 cgctattcca agcagcaaga gatttagcgt aaggatcgag tgcaagaaca gttttacctt
    18781 gacgctcgat ttggtattga taatagtagc cagtgaaatc tgtgattccg agtttgtttg
    18841 tgctgtctag agtttgtttc caagttcctc tttccccttt ttcgagagcg acagttccaa
    18901 ctactttgtc agggtcattc ttgtcgtaga caacaacaga aaccttatca gcacttggtg
    18961 accaaagggt caaatcaact tgttttcctt cttcttttag gtcagctccc agtttgccat
    19021 catagctgta tgtctcatct ttcaggcgcc agcttgtttt ggtagtgaat tggtcggaat
    19081 tgtagctaac agtataagga tgttttgtgt cagagaaatc tccgctgtag gtcactttct
    19141 taccagcttc atcgattgca acatcggtaa tagttacctt gtttcctagg tgattagtga
    19201 tgttggagtg tttgaggata tcttcttttt tagcaccgac aagtgttgaa aagctacttt
    19261 caatgctaga agtgcctacg tgttgggctc ctgtcatacg gatatcatgg acatagtatg
    19321 gatttgtgta aatcgattca tcatcgtctt ttaggaaaat ttggctatga tttttcaaat
    19381 ctgtgaactt ataattttct ttacggattt tcacgtcgtc tccttgtttg ctctcatcta
    19441 gtaataaaaa tccaaattct cttgcggctt cattaagagg aatgtcgata tagcggccat
    19501 atttgcctgt agccgtaaag tctgttccgt caggccattg agcgctactt ggatttttta
    19561 catctcccca gtaccagaga gatttcttgt catagttgcc atctgtgcgg tagtagttga
    19621 cgcgaacagt tcctgcaggc tgtggctcgt aagagaaaac cttgtaatct tggtctaacc
    19681 aagcttcgtt catttttgga actagttttt ctacagattt atcgccggtt agattttttc
    19741 cagctgtatt gttgatgagg aagctaattt tcttggcttg ttctcccttt aatttgacat
    19801 ctaggtaata gccgtagtca tctttcttgg catccttgaa ggacaaagct ccgtttggcc
    19861 agttttcaga tggtttttca acatcgtccc aagtccatag tccttgagca tccttgtttt
    19921 cttcaggaag ttttttgaca tggatacgga agtagttatc ttcgatgggc tcttctgcct
    19981 tagtttcagt tgttactgga ctagtagaag tagttggctc tgttgcaggt ttttcttctg
    20041 ttttctctag ggaagcgttt gcatttctag gtgaagaaat atcactttcg ttcttaccag
    20101 agccagctgc tgtatcagta agaggttggg caagggtggt tgtatttctg ttgttgggtt
    20161 cgttagtggt tggtgtactt tcgtcggatg agatagttgg tgtagccatg gcaagcaaga
    20221 caaggcttgc gccgataagg acagaaccag ttccattttt gagggaacgg atgctgtaga
    20281 ccattttttt ctcagtgtga gatggtgttt ttctcataat gattctccaa tcaataaatt
    20341 tctatatcag tatagcatgt agtaaaacaa tatgcaagcg ttttctttga tttgtgaaaa
    20401 aaattcctac ttttgagaag ttttctgtac tattttatat atcagtataa atgacggaga
    20461 taaaaatgtc acataagcca agccgtatta ttaggaagat gatgtgttcc cagctatttt
    20521 tattcagaaa ttgatctcta acattaccaa taaaaatgaa aaatatcttg acaagcaagg
    20581 gaaaattttg ttacaataat agacggtact ttttactttt ggtctctcaa gagtgtacag
    20641 ggacgtgctg acaaatgttg caaaagtaca cacagatgat atctgtcacc aagtgtatca
    20701 tcaccaaaaa taaaaaaaca caggagaatg tagatgccta caattaacca attggttcgc
    20761 aaaccgcgta aatcaaaagt agaaaaatct aaatcaccag ctttgaacgt tggttacaat
    20821 agtcataaaa aagttcaaac aaacgtttct tcaccacaaa aacgtggtgt tgcaactcgt
    20881 gttggaacaa tgacacctaa aaaacctaac tcagcccttc gtaaattcgc tcgtgtacgt
    20941 ttgagcaacc ttatcgaagt tactgcctac atcccaggta tcggacacaa cttgcaagag
    21001 cacagcgtgg tgcttcttcg cggtggacgt gtaaaagacc ttccaggggt acgttaccat
    21061 atcgtccgtg gtgcacttga tactgcaggt gttaacgatc gtaaacaagg ccgttctaaa
    21121 tacggtacta aacgtccaaa agcataagga aaggggataa agagaaatga gtcgtaaaaa
    21181 tagagctcca aaacgtgacg tattgccaga tccgctatac aattcacaac tagttactcg
    21241 tcttatcaac cgcgttatgc ttgatggtaa acgtggtact gctgcttcaa tcgtttacgg
    21301 tgcttttgag caaatcaaag aagctactgg caacgatgca cttgaagtat ttgaaacagc
    21361 tatggaaaac atcatgcctg tacttgaagt acgtgcacgt cgtgttggtg gttctaacta
    21421 ccaagtccca gttgaagttc gtccagaacg tcgtacaaca cttggacttc gttggttggt
    21481 aacaatcgct cgtcttcgtg gtgaacacac aatgcaagac cgtcttgcaa aagaaatctt
    21541 ggatgctgct aacaacactg gtgcagcagt taagaaacgt gaagatactc accgtatggc
    21601 tgaagctaac cgtgcattcg cacacttccg ttggtaagat aggatgcgaa agcgttaaga
    21661 aagtcccaga gaaaataggg aatcgaagca ggttgcggtt gcaaccaatg agattcatct
    21721 ttttctccag acttttagct tgagctcaac taaatcatga tgctaggcac ggtaaggatg
    21781 caaggtgaaa ataggaaact gacgcagtat tcaacgaata caaggagttt tatctttttc
    21841 acgcagcatc ccgttccagc tcacatcggc taactaactt tagcctgggt tcaaattagc
    21901 taaatcgatt agtattagct ataactcagc ttaccatctc gtaagttgaa accaacaata
    21961 gcatgaaaac attgagaacg ggtaggtcct gcctatccgt ttttattaaa atcgtgttat
    22021 aatagaatag aaatcaaaaa taaataggag aaacaaacct catggcacgc gaattttcac
    22081 ttgaaaaaac tcgtaatatc ggtatcatgg ctcacgtcga tgccggtaaa acaacaacta
    22141 ctgagcgtat tctttactac actggtaaaa tccacaaaat cggtgaaact cacgaaggtg
    22201 cgtcacaaat ggactggatg gagcaagagc aagaacgtgg tatcacgatc acatctgctg
    22261 cgacaacagc tcaatggaac aaccaccgcg taaacatcat cgacacacca ggacacgtgg
    22321 acttcacaat cgaagtacaa cgttctcttc gtgtattgga tggtgcggtt accgttcttg
    22381 actcacaatc aggtgttgaa cctcaaactg aaacagtttg gcgtcaagca actgagtacg
    22441 gagttccacg tatcgtattt gccaacaaaa tggacaaaat cggtgctgac ttcctttact
    22501 ctgtaagcac acttcacgat cgccttcaag caaatgcaca cccaatccaa ttgccaatcg
    22561 gttctgaaga tgacttccgt ggtatcattg acttgatcaa gatgaaagct gaaatctata
    22621 ctaacgacct tggtacggat atccttgaag aagacatccc agctgaatac cttgaccaag
    22681 ctcaagaata ccgtgaaaaa ttggttgaag cagttgctga aactgacgaa gaattgatga
    22741 tgaaatacct cgaaggtgaa gaaattacta acgaagaatt gaaagctggt atccgtaaag
    22801 cgactattaa cgttgaattc ttcccagtat tgtgtggttc agccttcaag aacaaaggtg
    22861 ttcaattgat gcttgatgcg gttattgact accttccaag cccacttgac atcccagcaa
    22921 tcaaaggtat taacccagat acagatgctg aagaaactcg tccagcatct gacgaagagc
    22981 catttgcagc tcttgccttc aagatcatga ctgacccatt cgtaggtcgt ttgacattct
    23041 tccgtgttta ctcaggtgtt cttcaatcag gttcatacgt attgaacact tctaaaggta
    23101 aacgtgaacg tatcggacgt attcttcaaa tgcacgctaa cagccgtcaa gaaattgaaa
    23161 ctgtttactc aggtgatatc gctgctgccg ttggtttgaa agatactaca actggtgact
    23221 cattgacaga tgaaaaagct aaaatcatcc ttgagtcaat caatgttcca gaaccagtta
    23281 tccaattgat ggttgagcca aaatctaaag ctgaccaaga caagatgggt atcgcccttc
    23341 aaaaattggc tgaagaagat ccaacattcc gcgttgaaac aaacgttgaa actggtgaaa
    23401 cagttatctc tggtatgggt gagcttcacc ttgacgtcct tgttgaccgt atgcgtcgtg
    23461 agttcaaagt tgaagcgaac gtgggtgctc ctcaagtatc ttaccgtgaa acattccgcg
    23521 cttctactca agcacgtgga ttcttcaaac gtcagtctgg tggtaaaggt caattcggtg
    23581 atgtatggat tgaatttact ccaaacgaag aaggtaaagg attcgaattt gaaaacgcaa
    23641 tcgtcggtgg tgtggttcct cgtgaattta tcccagcagt tgaaaaaggt ttggtagaat
    23701 ctatggctaa cggtgttctt gcaggttacc caatggttga cgttaaagct aaactttacg
    23761 atggttcata ccacgatgtc gactcatctg aaactgcctt caagattgcg gcttcacttg
    23821 ctcttaaaga agctgctaaa tcagcacaac cagcgatcct tgagccaatg atgcttgtaa
    23881 caatcactgt tccagaagaa aaccttggtg atgttatggg tcacgtaact gctcgtcgtg
    23941 gacgtgtaga tggtatggaa gcacatggta acagccaaat cgttcgtgct tacgttccac
    24001 tcgctgaaat gttcggttac gcaacagttc ttcgttctgc atctcaagga cgtggtacat
    24061 tcatgatggt atttgaccac tacgaagatg tacctaagtc agtacaagaa gaaatcatta
    24121 agaaaaacaa aggtgaagac taatcagtcc tcactctaga aggaagtcac ttagtggctt
    24181 ccttttgtct ttagaaaata cctctaaata tggtaaaata gtagaagaat aatgtgagga
    24241 aaatgaatgt caaatagttt tgaaattttg atgaatcaat tggggatacc tgttgaaatg
    24301 agacagcatc ctgctttaac acaggcagat attgagcgag tcgtggttca taaaattagt
    24361 aaggtatggg agtttcattt cgtattttct aatattttac cgattgaaat ctttttagaa
    24421 ttaaagaaag ggctgagtga ggaattttct aagacaggca ataaagctgt tttcgaaatc
    24481 aaggttctgt ctcaagattt ttcaaatcaa ctcttgcagg cttattatag agaagctttt
    24541 tctgagggtc catgtgctag tcaaagtttt aagtctcttt atcaaaattt gcaagttcgt
    24601 gctgagggga atcaactctt tattgaagga tctgaggcga ttgataagga acactttaag
    24661 aaaaatcacc ttcctaattt agcaaaacaa cttgaaaagt ttggttttcc aacttttaac
    24721 tgtcaggtcg agaagaatga tgtgctgacc caagagcagg aagatgcctt ccatgctgaa
    24781 aatgagcaga ttgttcaagc ggccaatgag gaagcgctcc gtgctatgga acaactagaa
    24841 cagatggcgc cacctccagc ggaagagaaa ccagcctttg attttcaaac gaaaaaagct
    24901 gcagctaaac ccaagctaga taaggcggag attactccta tgatcgaagt gacgacggag
    24961 gaaaatcgtc tggtctttga aggggttgtg tttgatgtgg agcaaaaagt gaccagaaca
    25021 gggcgtgttt tgatcaactt taaaatgacg gactacactt caagtttttc gatgcaaaag
    25081 tgggtaaaaa atgaggaaga ggctcagaaa tttgatctca tcaagaagaa ttcttggctc
    25141 cgagttcgtg ggaatgtgga gatgaataac ttcacacgcg atttgactat gaatgtgcag
    25201 gatgtgcagg aagttgttca ctatgagcgg aaggatttga tgccagaagg tgagcgtcgg
    25261 gttgagtttc acgctcatac taacatgtcg actatggatg ctctaccaga ggttgaagaa
    25321 atcgttgcta cagctgctaa gtggggacac aaagcagttg ctatcaccga ccacgggaat
    25381 gttcaatcct tcccacacgg ctataaggcg gctaagaaag cgggaatcca gctaatctat
    25441 gggatggaag ccaatatcgt ggaggaccgt gtccctatcg tctataacga agtggagagg
    25501 gacttgtcag aagcgaccta cgtggtcttt gacgtggaaa cgacgggtct atcagccatc
    25561 tataatgatt tgattcaggt tgcggcctct aagatgtaca aggggaatgt cattgctgaa
    25621 tttgatgaat ttatcaatcc tgggtatccc ttgtcagctt ttactactga gttgactgga
    25681 attacagatg atcacgtcaa aaatgccaaa ccactagaac aagttctgca agaattccaa
    25741 gaattctgca aggatacggt cctagttgcc cacaatgcga cctttgacgt tggctttatg
    25801 aatgccaact atgagcgtca tggtcttcct aaaattagcc agccagttat tgatacgctg
    25861 gagtttgcta gaaacctcta tcctgagtat aaacgtcatg gtttggggcc tttgactaag
    25921 cgttttggtg tggctttgga acatcaccac atggccaatt acgatgcgga agctactggt
    25981 cgtctgctct ttatttttat caaagaagta gcagaaaaac atggagtgac cgatctagct
    26041 agactcaaca ttgatttgat tagtccagat tcttataaaa aagctcggat caagcatgcg
    26101 actatttatg tcaagaatca ggtaggtcta aaaaatatct ttaagctagt ttctttgtcc
    26161 aatactaagt actttgaagg ggtgccacga attccgagaa cagttctaga tgcccatcgg
    26221 gaaggtttga ttttaggttc agcttgctct gaaggtgaag tttttgatgc ggttgtttcc
    26281 caaggtgtgg atgcggcggt tgaggtggcc aagtattatg actttatcga ggtcatgcca
    26341 ccagctatct atgctccctt gattgccaag gagcaggtca aggatatgga agaactccag
    26401 actattatca agaatttgat agagatcggc gaccgtcttg gcaagcccgt tttggctacg
    26461 ggaaatgtcc actatatcga accagaagaa gaaatttacc gtgaaattat cgtccgcagt
    26521 ttgggtcagg gggcgatgat taaccgaacc atcggtcatg gtgaacatgc ccaaccagca
    26581 ccacttccaa aggctcattt tagaacgact aatgagatgt tggatgaatt tgccttcttg
    26641 ggagaggaac tagcccggaa attggttatt gaaaacacca atgccttggc agaaatcttt
    26701 gaacccgttg aggtagttaa gggtgacttg tatacgcctt tcattgacaa ggctgaagaa
    26761 acagttgctg agttgaccta taagaaagct tttgagattt atggaaatcc gttgccagat
    26821 attgttgatt tgcgaattga aaaagaattg acttccattc tggggaatgg atttgctgtg
    26881 atttatctgg catcgcagat gctggttcaa cgttccaatg aacggggtta cctggtgggt
    26941 tctcgtgggt ctgtaggatc tagtttcgtt gcgactatga ttggtattac ggaggttaat
    27001 cctctctctc ctcactatgt ctgtggtcag tgtcaataca gcgagtttat caccgatggt
    27061 tcttatggtt caggttttga tatgcccaat aaggactgtc caaactgcgg tcacaaactc
    27121 agtaaaaacg gacaggatat tccgtttgag accttccttg gctttgatgg ggataaggtt
    27181 cctgatattg acttgaactt ctcgggagaa gatcagccta gcgcccactt ggatgtgcgt
    27241 gatatctttg gtgaagaata tgccttccgt gcgggaacgg ttggtacggt agctgccaag
    27301 actgcctatg gatttgtcaa gggttacgag cgagattatg gcaagtttta tcgtgatgca
    27361 gaagtagaac gcctcgctca aggagcggcg ggtgtcaagc ggacaacagg ccaacacccg
    27421 gggggaatcg ttgttattcc gaactacatg gatgtctacg attttacgcc tgtccagtat
    27481 ccagcagatg atgtcacggc tgaatggcag accactcact ttaacttcca cgatatcgat
    27541 gagaacgtcc tcaaactcga tgtactggga catgatgatc cgaccatgat tcgaaaactt
    27601 caggatttgt ctggtattga ccctaatgaa attcctatgg atgacgaagg cgtgatggca
    27661 ctcttttctg ggactgatgt gctaggggta acacctgaac aaattggaac gcctacgggt
    27721 atgttgggga ttccagagtt tggaacaaat ttcgtacgtg gaatggtaga cgaaacccat
    27781 ccgacaacct ttgcggaatt gcttcagctg tctggtctgt cccacggtac tgacgtttgg
    27841 ttggggaatg ctcaggatct gattaagcaa ggaatagcgg acctatcgac tgttatcggt
    27901 tgtcgggacg acatcatggt ttacctcatg catgcgggtc tggaacctaa gatggccttt
    27961 accattatgg aacgggtacg taagggtttg tggctaaaga tttcagaaga ggagagaaat
    28021 gactatatcg aagccatgaa ggccaataag gtgccagagt ggtatatcga atcctgtggg
    28081 aaaattaagt acatgttccc taaggcccat gcggcagcct acgttatgat ggccttgcgt
    28141 gtagcttact tcaaggttca ccatcctatt tattactact gtgcttactt ctccattcgt
    28201 gctaaggctt ttgatatcaa gaccatgggt gcgggcttgg aggtcatcaa gcgcagaatg
    28261 gaagaaatct ctgaaaaacg gaagaacaat gaagcctcta atgtggaaat cgatctctat
    28321 acaactcttg agattgtcaa tgagatgtgg gaacgaggtt tcaagtttgg caaattagat
    28381 ctctaccgta gtcaggcgac agagttcctc atcgacgggg atacccttat cccaccattt
    28441 gtagcaatgg atggtctggg agagaacgtt gccaagcaac tggtgcgggc gcgtgaagag
    28501 ggagaattcc tctctaaaac agaactacgc aagcgtggtg gactctcatc aaccttggtt
    28561 gaaaagatgg atgagatggg tattcttgga aatatgccag aggataacca gttgagtttg
    28621 tttgatgagt tgttttaaaa aattgcttaa taatctatta aaagaggcta acgtatatcc
    28681 aatagattta cattagcttt cttttttgtt aaaatagtct atggaaagag ggtgagagta
    28741 tgtcaaagat gagtataagc atccgtctgg atagtgaggt taaggagcag gcccaacagg
    28801 tgtttagtaa tctgggaatg gatatgacaa cagctattaa tattttcctt cgtcaggcaa
    28861 ttcaatatca gggattacct tttgatgtta gactagacga aaatcggaag ttgctccaag
    28921 cgttaacgga tttagaccaa aatcgtaata tgagccagtc ttttgaatca gtctcagatt
    28981 tgatggagga cttacgtgct taagattcgt tatcataaac agtttaaaaa agattttaag
    29041 ttggctatga agcgtggttt gaaggcagaa ttattagaag aagttttgaa ttttctggtt
    29101 caagaaaaag aacatcctgc cagatatcgt gatcattcat tgacggcatc caagcatttt
    29161 caaggagttc gtgaatgcca tacccagcca gattggcttt tggtttataa agtagacaag
    29221 tcggaattga ttttaaattt gctgaggaca ggcagtcaca gtgatttatt ttaatctatt
    29281 ttaagggggt tctcatgaaa ctaagaatat ttgcggaaga taagccggct aagaaggtat
    29341 ttgaatatca attagaactt gctgatcgta caattcttct atcgacagca ctcttgtcag
    29401 gtgctattgc tttagcagga atcttttctg ctttgagaga aaaataaaaa tagaaaagag
    29461 aaaacagaat ggttttacca aattttaaag aaaatctaga aaaatatgcg aaattgttgg
    29521 ttgcgaacgg aattaacgtg caacctggtc acactttggc tctttctatt gatgtggagc
    29581 aacgtgaatt ggcacatcta atcgtgaaag aagcttatgc cttgggtgcg catgaggtca
    29641 tcgttcagtg gacagatgat gtgattaacc gtgagaaatt cctccatgcc ccgatggagc
    29701 gtttggacaa tgtgccagaa tacaagattg ctgagatgaa ctatctcttg gagaacaagg
    29761 ctagccgtct tggagttcgt tcatctgatc caggtgcctt gaacggagtg gacgctgaca
    29821 agctttcagc ttctgctaaa gctatgggac ttgccatgaa gcctatgcgt atcgcaactc
    29881 aatctaacaa ggttagctgg actgtagcag ctgcagcagg acttgagtgg gctaagaaag
    29941 tcttcccaaa tgctgcgagc gacgaagaag cagttgattt cctttgggac caaattttca
    30001 aaacttgccg tgtctacgaa gcagatcctg ttaaggcttg ggaggaacat gcagccattc
    30061 tcaagagcaa ggccgatatg cttaataagg agcaattttc agcccttcac tacacagcgc
    30121 caggaacaga tttaacactt ggtttgccaa agaaccacgt ttgggaatca gctggtgctg
    30181 tcaatgcaca gggcgaagaa ttcttgccaa atatgccaac agaagaggtc ttcacagcgc
    30241 ctgacttccg tcgtgcagat ggttatgtca cttctacaaa accgcttagc tacaacggaa
    30301 atatcattga aggcattaag gtgaccttta aggatggaca aatcgtagat atcactgctg
    30361 agaagggtga tcaggttatg aaagaccttg tctttgaaaa tgcgggtgcg cgtgccttgg
    30421 gtgaatgtgc cttggtacca gatccaagtc caatttctca gtcaggcatt accttcttta
    30481 acaccctttt cgatgaaaat gcgtcaaacc acttggctat cggtgcagcc tatgcgacta
    30541 gcgttgttga tggagcggag atgagcgaag aggagcttga agctgcaggg cttaaccgtt
    30601 cagatgttca cgtagacttt atgattggtt ctaaccaaat ggatatcgat ggtattcgtg
    30661 aggatggaac gcgggtacct cttttccgta atgggaattg ggcaaattaa ggagataata
    30721 tgttaggaag tatgttcgtt ggtctcctag tgggattttt agcaggtgct atgaccaatc
    30781 gtggagagcg aatgggatgt tttggaaaaa tgtttctcgg ttggatcgga gcctttctag
    30841 gtcacttgct ctttggaact tgggggccag ttttatcagg aacagctatt atcccagcga
    30901 ttttaggagc catgattgtt ttagctattt tttggagacg aggaagttaa tttcctaaat
    30961 ct
//
LOCUS       DAVBOG010000026        30137 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.026, whole genome shotgun sequence.
ACCESSION   DAVBOG010000026 DAVBOG010000000
VERSION     DAVBOG010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 30137)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30137)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30137
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.026"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..126)
                     /locus_tag="VQ865_001226"
     CDS             complement(<1..126)
                     /locus_tag="VQ865_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HET3135560.1"
                     /translation="MNDEASKQLTDARFKRLVGVQRTTFEEMLAVLKTAYQLKHAK"
     gene            complement(134..574)
                     /locus_tag="VQ865_001227"
     CDS             complement(134..574)
                     /locus_tag="VQ865_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000335589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3135561.1"
                     /translation="MCLICQRIELIKKGENPYFVKELETGYLVIGDHQYFAGYSLFLA
                     KEHVTELHHLKKETRLRFLEEMSVVQEAVAKAFAAEKMNIELLGNGDAHLHWHLFPRR
                     TGDMNGHGLNGRGPVWWVPFEEMTAETRQAKPDEIRLPAKQNMV"
     gene            complement(576..1613)
                     /locus_tag="VQ865_001228"
     CDS             complement(576..1613)
                     /locus_tag="VQ865_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HET3135562.1"
                     /translation="MNQTVEYIKELTAIASPTGLTREISNYLVKTLEGFGYQPVRTAK
                     GGVNVTIKGQNDEQHRYVTAHVDTLGAIVRAVKPDGRLKLDRIGGFPWNMIEGENCTV
                     HVASTGQKVSGTILIHQTSCHVYKDAGTAERTQDNMEVRLDVKVSNEKETRALGIEVG
                     DFISFDPRTVVTDTGFIKSRHLDDKVSAAILLNLLRIYKKEKIELPVTTHFAFSVFEE
                     VGHGANSNIPAQVVEYLAVDMGAMGDDQQTDEYTVSICVKDASGPYHYDFRQHLVALA
                     KEQDIPFKLDIYPFYGSDASAAMSAGAEVKHALLGAGIESSHSYERTHIDSVVATERM
                     VDAYLRSNLVD"
     gene            complement(1711..3036)
                     /gene="brnQ"
                     /locus_tag="VQ865_001229"
     CDS             complement(1711..3036)
                     /gene="brnQ"
                     /locus_tag="VQ865_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006152071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HET3135563.1"
                     /translation="MAKKGTLTGLLLFGIFFGAGNLIFPPSLGALSGEHFLPAIAGFV
                     FSGVGIAVLTLIIGTLNPKGYIYEISTKIAPWFATLYLSVLYLSIGPFFATPRTATTA
                     YEVGISPLLSDANKGLGLIVFTVLYFAAAYLISLNPSKILDRIGRILTPVFAILIVIL
                     VVLGAIKYGGTSPQAASAAYQASAFGTGFLEGYNTLDALASVAFSVIAVQTLKQLGFS
                     SKKEYISTIWVIGIVVALAFSALYIGLGFLGNHFPVPAEAMKGGTPGVYILSQATQEI
                     FGSTAQLFLAAMVTVTCFTTTVGLIVSTAEFFNERFPQISYKVYATAFTLIGFAIANL
                     GLDAIIKYSIPVLVILYPITIAIVMIVIVNKFVALSKPGMQLTIAVVTVIAIASVLGS
                     SFKVEFLANLVSVLPFAKASLPWLVPAIVGILLSLVLPNKQESDVFEME"
     gene            complement(3207..3299)
                     /locus_tag="VQ865_001230"
     CDS             complement(3207..3299)
                     /locus_tag="VQ865_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3135564.1"
                     /translation="MRSARACQFLLEQGYNVINVQGGMLAFEEL"
     gene            complement(3342..3494)
                     /locus_tag="VQ865_001231"
     CDS             complement(3342..3494)
                     /locus_tag="VQ865_001231"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3135565.1"
                     /translation="MKEIAFDAFYQLYQNDQLSLVDVREVDEFAALHLECAHNLPLSQ
                     LADSYD"
     gene            complement(3654..4232)
                     /locus_tag="VQ865_001232"
     CDS             complement(3654..4232)
                     /locus_tag="VQ865_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase family protein"
                     /protein_id="HET3135566.1"
                     /translation="MSQIERIKQAIMADSQNASYTERGIEPLFAAPKTARINIIGQAP
                     GLKTQEAGLYWKDKSGDRLRDWLGVDEDTFYNSGYFAVLPMDFYFPGHGKSGDLPPRT
                     GFAEKWHPQLLQELPDIQLTLLIGQYAQAYYLQEKISGKVTERVKHYKDYLPAYFPLV
                     HPSPRNQIWMAKNPWFEAEVVPDLKKRIKTIL"
     gene            complement(4286..5686)
                     /gene="pepV"
                     /locus_tag="VQ865_001233"
     CDS             complement(4286..5686)
                     /gene="pepV"
                     /locus_tag="VQ865_001233"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HET3135567.1"
                     /translation="MTAIDFTAEVEKRKEDLLADLFSLLEINSERDDSKADAQHPFGP
                     GPVKALEKFLEIADRDGYPTKNVDNYAGHFEFGDGEEVLGIFAHMDVVPAGSGWDTDP
                     YTPTIKDGRLYARGASDDKGPTTACYYGLKIIKELGLPTSKKVRFIVGTDEESGWADM
                     DYYFEHVGLAKPDFGFSPDAEFPIINGEKGNITEYLHFAGENTGAARLHSFTGGLREN
                     MVPESATAVVSGDLADLQAKLDAFVAEHKLRGELQEEAGKYKVTIIGKSAHGAMPASG
                     VNGATYLALFLSQFGFAGPAKDYLDIAGKILLNDHEGENLKIAHVDEKMGALSMNAGV
                     FRFDETSADNTIALNIRYPKGTSPEQIKSILENLPVVSVSLSEHGHTPHYVPMEDPLV
                     QTLLNIYEKQTGLKGHEQVIGGGTFGRLLERGVAYGAMFPDSIDTMHQANEFIALDDL
                     FRAAAIYAEAIYELIK"
     gene            complement(5699..6304)
                     /locus_tag="VQ865_001234"
     CDS             complement(5699..6304)
                     /locus_tag="VQ865_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002924506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HET3135568.1"
                     /translation="MKFLELNKKRHATKHFTDKPVDPKDVRTAIEIATLAPSAHNSQP
                     WKFVVVREKNAELAKLAYGSNFEQVSSAPVTIALFTDTDLAKRARKIARVGGANNFSE
                     EQLQYFMKNLPAEFARYNEQQVSDYLALNAGLVAMNLVLALTDQGIGSNIILGFDKSK
                     VNEVLEIEDRFRPELLITVGYTDDKLEPSYRLPVDEIIEKR"
     gene            6475..7275
                     /locus_tag="VQ865_001235"
     CDS             6475..7275
                     /locus_tag="VQ865_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000714621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135569.1"
                     /translation="MKKFSLLLAILPFLVACGNQATPKETSAQKTIVLATAGDVPPFD
                     YEDKGNLTGFDIEVLKAVDEKLSDYEIQFQRTAWESIFPGLDSGHYQAAANNLSYTKE
                     RAEKYLYSLPISNNPLVLVSNKKNPLTSLDQIAGKTTQEDTGTSNAQFINNWNQKHTD
                     NPATINFSGEDIGKRILDLANGEFDFLVFDKVSVQKIIKDRGLDLSVVDLPSADSPSN
                     YIIFSSDQKEFKEQFDKALKELYQDGTLEKLSNTYLGGSYLPDQSQLQ"
     gene            complement(7457..8254)
                     /locus_tag="VQ865_001236"
     CDS             complement(7457..8254)
                     /locus_tag="VQ865_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001015777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase family protein"
                     /protein_id="HET3135570.1"
                     /translation="MNHKIAILSDVHGNATALEAVIADAKNQGASEYWLLGDIFLPGP
                     GANDLVALLKDLPITASVRGNWDDRVLEALDGQYGLEDPQEVQLLRMTQYLMERMDPA
                     TIVWLRSLPLLEKKEIDGLRFSISHNLPDKNYGGDLLDAETDVAVYGHVHKQLLRYGS
                     QGQQIINPGSIGMPYFNWEALKNHRAQYAVIEVEDGELLNIQFRKVAYDYEAELELAK
                     SKGLPFIEMYEELRRDDNYQGHNLELLASLIEKHGYVEDVKNFFDFL"
     gene            complement(8244..10088)
                     /gene="uvrC"
                     /locus_tag="VQ865_001237"
     CDS             complement(8244..10088)
                     /gene="uvrC"
                     /locus_tag="VQ865_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HET3135571.1"
                     /translation="MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSY
                     FRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEINLIKENKPKYNIMLKDDKSYPFI
                     KITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
                     YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERA
                     AEYRDLIQAIGTLRTKQRVMAKDLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNL
                     FPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKALVDSKILKPQRGEKK
                     QLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGT
                     SPVSAMVVFVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLI
                     VIDGGQGQVNIAKQVIQEELGLDIPIAGLQKNDKHQTHELLFGDPLEVVDLSRNSQEF
                     FLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSLTKIKEA
                     SVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP"
     gene            complement(10128..10829)
                     /locus_tag="VQ865_001238"
     CDS             complement(10128..10829)
                     /locus_tag="VQ865_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001267193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="matrixin family metalloprotease"
                     /protein_id="HET3135572.1"
                     /translation="MRWLFRLIGAFFSFVWRLFWRLVWIVVLLCVLAFGLLWYLNGDF
                     QGALKQAERSVKIGQQSIDQWEKTGQLPKLSQTDSHQHSEGRWAQASARIYLDPQMDS
                     RFQEAYLEAIQNWNQTGAFNFELVTESSKADITATEMNDGGTPVAGEAESQTNLLTGQ
                     FLSVTVRLNHYYLSNPYYGYSYERLVHTAEHELGHAIGLDHTDEKSVMQPAGSFYGIQ
                     EEDVANLRKIYETSE"
     gene            complement(10908..12140)
                     /gene="murN"
                     /locus_tag="VQ865_001239"
     CDS             complement(10908..12140)
                     /gene="murN"
                     /locus_tag="VQ865_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurN"
                     /protein_id="HET3135573.1"
                     /translation="MALTTLTKEEFQTYSDQVSSRSFMQSVQMGDLLEKRGARIVYLA
                     LKQEGEIQVAALVYSLPMLGGLHMELNSGPIYTQQDALPVFYAELKEYAKQNGVLELL
                     VKPYETYQTFDSQGNPIDAEKKSIIQGLTDLGYQFDGLTTGYPGGEPDWLYYKDLTEL
                     TEKSLLKSFSKKGKPLVKKAETFGIRLKKLKREELSIFKNITKETSERREYSDKSLEY
                     YEHFYDTFGEQAEFLIASLNFSDYMSKLQGEQSKLEENLDKLRLDLSKNPHSEKKQNQ
                     LREYSSQFETFEVRKAEARDLIEKYGEEDIVLAGSLFVYMPQETTYLFSGSYTEFNKF
                     YAPALLQKYVMLESIKRGIPKYNFLGIQGIFDGSDGVLRFKQNFNGYIVRKAGTFRYH
                     PSPLKYKAIQLLKKIVGR"
     gene            complement(12145..13365)
                     /gene="murM"
                     /locus_tag="VQ865_001240"
     CDS             complement(12145..13365)
                     /gene="murM"
                     /locus_tag="VQ865_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001819885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan bridge formation alanyltransferase
                     MurM"
                     /protein_id="HET3135574.1"
                     /translation="MYRYQIGIPTLEYDQFVKEHELANVLQSSAWEEVKSNWQHEKFG
                     VYREEKLLATASILIRTLPLGYKMFYIPRGPILDYGDKELLNFVIQSIKSYARSKRAV
                     FVTFDPSICLSQSLINQEKTEFPENLAIIDSLQQMGVRWSGKTEEMGDTIQPRIQAKI
                     YKENFEEDKLSKSTKQAIRTARNKGLEIQYGGLELLDSFSELMKKTEKRKEIHLRNEA
                     YYKKLLDNFKDKAYITLATLDVSKRSQELEEQLAKNRALEETFTESTRISKVEAQKKE
                     KERLLEELTFLQEYIDVGQARVPLAATLSLEFGTTSVNIYAGMDDDFKRYNAPILTWY
                     ETARYAFERGMVWQNLGGVENSLNGGLYHFKEKFNPTIEEYLGEFTMPTHPLYPLLRL
                     ALDFRKTLRKKHRK"
     gene            complement(13477..14256)
                     /locus_tag="VQ865_001241"
     CDS             complement(13477..14256)
                     /locus_tag="VQ865_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HET3135575.1"
                     /translation="MAVMKIEYYSQVLDMEWGVNVLYPDANRVEEPECEDIPVLYLLH
                     GMSGNHNSWLKRTNVERLLRGTNLIVVMPNTSNGWYTDTQYGFDYYTALAEELPQVLK
                     RFFPNMTSKREKTFIAGLSMGGYGCFKLALATNRFSHAASFSGALSFQNFSPESQNLG
                     SPAYWRGVFGEIKDWTTSPYSLESLAKKSDKKTKLWAWCGEQDFLYEANNLAVKNLKK
                     LGFDVTYSHSAGTHEWYYWEKQLEVFLTTLPIDFKLEERLT"
     gene            complement(14325..15986)
                     /locus_tag="VQ865_001242"
     CDS             complement(14325..15986)
                     /locus_tag="VQ865_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HET3135576.1"
                     /translation="MSNISLTTLGGVRENGKNMYIAEIGESIFVLNVGLKYPENEQLG
                     VDVVIPNMDYLFENSDRIAGVFLTHGHADAIGALPYLLAEAKVPVFGSELTIELAKLF
                     VKGNDAVKKFNDFHVIDENTEIDFGGTVVSFFPTTYSVPESLGIVLKTSEGSIVYTGD
                     FKFDQTASESYATDFARLAEIGRDGVLALLSDSANADSNIQVASESEVRDEITQTIAD
                     WEGRIIVAAVSSNLSRIQQIFDAADKTGRRIVLTGFDIENIVRTAIRLKKLSLANEIL
                     LIKPKDMSRFEDHELIILETGRMGEPINGLRKMSIGRHRYVEIKDGDLVYIATAPSIA
                     KEAFVARVENMIYQAGGVVKLITQSLHVSGHGNVRDLQLMINLLQPKYLFPVQGEYRE
                     LDAHAKAAMAVGMLPEHIFIPKKGTTMAYENGDFVPAGSVSAGDILIDGNAIGDVGNV
                     VLRDRKVLSEDGIFIVAITVNRREKKIVARARVHTRGFVYLKKSRDILHESSELINQT
                     VEEYLQGDDFDWADLKGKVRDNLTKYLFDQTKRRPAILPVVMEAK"
     gene            complement(16161..18383)
                     /gene="recJ"
                     /locus_tag="VQ865_001243"
     CDS             complement(16161..18383)
                     /gene="recJ"
                     /locus_tag="VQ865_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001832038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HET3135577.1"
                     /translation="MITPTYEWQFALQVEDADFTKIAKKAGLGPEVARLLFERGIQDQ
                     ESLKKFLEPSLEDLHDAYLLHDMDKAVERIRQAIEEGENILVYGDYDADGMTSASIVK
                     ESLEQLGAECRVYLPNRFTDGYGPNASVYKYFIEQEGISLIVTVDNGVAGHEAIALAQ
                     SMGVDVIVTDHHSMPETLPDAYAIVHPEHPDADYPFKYLAGCGVAFKLACALLEEVQV
                     ELLDLVAIGTIADMVSLTDENRILVQYGLEMLGHTQRIGLQEMLDMAGIAANEVTEET
                     VGFQIAPRLNALGRLDDPNPAIDLLTGFDDEEAHEIALMIHQKNEERKEIVQSIYEEA
                     KTMVDPEKKVQVLAKEGWNPGVLGIVAGRLLEELGQTVIVLNIEDGRAKGSARSVEAV
                     DIFEALDPHRDLFIAFGGHAGAAGMTLEVEQLSDLSQVLEDYVREKGADAGGKNKLNL
                     DEELDLEALSLETVKSFERLAPFGMDNQKPIFYIKNFQVESARTMGAGNAHLKLKISK
                     GEASFEVVAFGQGRWATEFSQTKNLELAVKLSVNQWNGQTALQLMMVDARVEGVQLFN
                     IRGKNAVLPEGVPVLDFPGELPNLAASEAIVVKNIPEDITQLKTIFQEQHFSAVYFKN
                     DIDKAYYLTGYGTRDQFAKLYKTIYQFPEFDIRYKLKDLAAYLNIQQILLVKMIQVFE
                     ELGFVTIKDGVMTVNKEAPKREIGESQIYQNLKQTVKDQEMMALGTVQEIYDFLMEKE
                     "
     gene            18660..19418
                     /locus_tag="VQ865_001244"
     CDS             18660..19418
                     /locus_tag="VQ865_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3135578.1"
                     /translation="MALVEFKNVEKYYGDYHALRNINLRFEKGQVVVLLGPSGSGKST
                     LIRTINGLEAVDKGSLLVNGHQVAGASQKDLVPLRKEVGMVFQHFNLYPHKTVLENVT
                     LAPIKVLGIDKKEAEKTAQKYLEFVNMWDKKDSYPAILSGGQKQRIAIARGLAMHPEL
                     LLFDEPTSALDPETIGDVLAVMQKLAHDGMNMIIVTHEMGFAREVADRIIFMADGEVL
                     LDTTDVDNFFDNPSKPRAQQFLSKIINHESDKVK"
     gene            19429..20223
                     /locus_tag="VQ865_001245"
     CDS             19429..20223
                     /locus_tag="VQ865_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000726191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HET3135579.1"
                     /translation="MKKKFFLSALLISLFGLAAAKPVQADTSIADIQKRGELVVGVKQ
                     DVPNFGYKDPKTGTYSGIETDLAKMVADELKVKIRYVPVTAQTRGPLLDNEQVDMDIA
                     TFTITDERKKLYNFTSPYYTDASGFLVNKSAKIKKIEDLNGKTIGVAQGSITQRLITE
                     LGKKKGLKFKFVELGSYPELITSLHAHRIDAFSVDHSILSGYTSKRTALLDDSFKPSD
                     YSIVTKKSNTELNDYLDNLVTKWSKDGSLQKLYDRYKLKPSSHTAD"
     gene            20236..20913
                     /locus_tag="VQ865_001246"
     CDS             20236..20913
                     /locus_tag="VQ865_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3135580.1"
                     /translation="MTDLSSWTAYFQDFGQFFNGFLFTLALAIGSFILAMVLGIFFGA
                     MSTSKRPILRILARIFVEFYQNTPLLVQFVIVFYGLPLISDHIIMIPIYWTAVLCVGL
                     YHGAYIAEVIRSGIQSIPSGQMEAALSQGFTYISAMRLIILPQAFRIILPPLTNQIVN
                     LIKNTSTVAIISGVDLMFVTKSWSALNGNYIPAFLGAALLYFALCFPVAQFGRKMEQA
                     NKKAYSL"
     gene            20923..21582
                     /locus_tag="VQ865_001247"
     CDS             20923..21582
                     /locus_tag="VQ865_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3135581.1"
                     /translation="MESILEILTPDNLVFIFKGFGLTLYISLIAIILSTIIGTVLAVM
                     RNGKNPILRIISSIYIEFVRNVPNLLWIFTIFLVFKMKSTPAGITAFTLFTSAALAEI
                     IRGGLNAVDKGQYEAGMSQGFTSAQILYYIILPQAIRKMLPAIISQFVTVIKDTSLLY
                     SVIALQELFGASQILMGRYFEPEQVFSLYILIALIYFSFNLAISSLSHMLAKRWQQAA
                     E"
     gene            21819..22943
                     /locus_tag="VQ865_001248"
     CDS             21819..22943
                     /locus_tag="VQ865_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HET3135582.1"
                     /translation="MEFSMKSVKGLLFIIASFILTLLTWMNTSPQFMIPGLALTSLSL
                     TFILATRLPLLESWFHGLEKVYTVHKFTAFLSIILLIFHNFSMGGLWGSRLAAQFGNL
                     AIYIFASIILVAYLGKYIQYEAWRWIHRLVYLAYILGLFHIYMIMGNRLLTFNLLSFL
                     VGSYALLGLLAGFYIIFLYQKISFPYLGKITHLKRLNHDTREIQIHLSRPFNYQSGQF
                     AFLKIFQEGFESAPHPFSISGGHGQTLYFTVKNSGDHTNNIYDNLQAGSKVTLDRAYG
                     HMIIEEGRENQVWIAGGIGITPFISYIREHPILDKQVHFYYNFRGDENAVYLDLLRNY
                     AQKNPNFELHLIDSTKDGYLNFEQKKCPNMQPSICVVLFL"
     gene            complement(23341..24222)
                     /locus_tag="VQ865_001249"
     CDS             complement(23341..24222)
                     /locus_tag="VQ865_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HET3135583.1"
                     /translation="MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAP
                     VLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTS
                     IMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAK
                     AMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQI
                     QAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAI
                     QASVEERIDVFGSEGKA"
     gene            complement(24363..25691)
                     /gene="vncS"
                     /locus_tag="VQ865_001250"
     CDS             complement(24363..25691)
                     /gene="vncS"
                     /locus_tag="VQ865_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase VncS"
                     /protein_id="HET3135584.1"
                     /translation="MKRTGLFTKIFIYTFSIFSVLVICLHLAIYFLFPSTYLSHRQET
                     IGQKATAIAQSLEGKDRQSIEQVLDLYSQTSDIKGTVKGEMTEDKLEVKDSLPLDTDR
                     QTTSLFIEEREVKTQDGGTMILQFLASMDLQKEAEQISLQFLPYTLLASFLISLLVAY
                     IYARTIVAPILEIKRVTRRMMDLDSQVRLRVDSKDEIGNLKEQINSLYQHLLTVIADL
                     HEKNEAILQLEKMKVEFLRGASHELKTPLASLKILIENMRENIGRYKNRDQYLGVALG
                     IVDELNHHVLQILSLSSVQELRDDRETIDLLQMTQNLVKDYALLAKERELQIDNSLTH
                     QQAYLNPSVMKLILSNLISNAIKHSVPGGLVRIGEREGELFIENSCSSEEQEKLAQSF
                     SDNASRKVKGSGMGLFVVKSLLEHEKLAYRFEMEENRLTFFIDFPKVVQD"
     gene            complement(25688..26344)
                     /gene="vncR"
                     /locus_tag="VQ865_001251"
     CDS             complement(25688..26344)
                     /gene="vncR"
                     /locus_tag="VQ865_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor VncR"
                     /protein_id="HET3135585.1"
                     /translation="MKILIVEDEEMIREGVSDYLTDCGYETIEAADGQEALEQFSSYE
                     VALVLLDIQMPKLNGLEVLAEIRKTSQVPVLMLTAFQDEEYKMSAFASLADGYLEKPF
                     SLSLLKVRVDAIFKRYYDTGRIFSYKDTKVDFESYSASLAGQEVPINAKELEILDYLV
                     KNEGRALTRSQIIDAVWKATDEVPFDRVIDVYIKELRKKLDLDCILTVRNVGYKLERK
                     "
     gene            complement(26393..26476)
                     /gene="pep27"
                     /locus_tag="VQ865_001252"
     CDS             complement(26393..26476)
                     /gene="pep27"
                     /locus_tag="VQ865_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_198523890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative autolysis signal peptide Pep27"
                     /protein_id="HET3135586.1"
                     /translation="MRKEFHNVLSSGQLLTDKRPARDYNRK"
     gene            complement(26657..28036)
                     /gene="vex3"
                     /locus_tag="VQ865_001253"
     CDS             complement(26657..28036)
                     /gene="vex3"
                     /locus_tag="VQ865_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit Vex3"
                     /protein_id="HET3135587.1"
                     /translation="MLHNAFAYVTRKFFKSIVIFLIILLMASLSLVGLSIKGATAKAS
                     QETFKNITNSFSMQINRRVNQGTPRGAGNIKGEDIKKITENKAIESYVKRINAIGDLT
                     GYDLIETPETKKNLTADRAKRFGSSLMITGVNDSSKEDKFVSGSYKLVEGEHLTNDDK
                     DKILLHKDLAAKHGWKVGDKVKLDSNIYDADNEKGAKETVEVTIKGLFDGHNKSAVTY
                     SQELYENTAITDIHTAAKLYGYTEDTAIYGDATFFVTADKNLDDVMKELNGISGINWK
                     SYTLVKSSSNYPALEQSISGMYKMANLLFWGSLSFSVLLLALLLSLWINARRKEVGIL
                     LSIGLKQASILGQFITESILIAIPALVSAYFLANYTARAIGNTVLANVTSGVAKQASK
                     AAQASNLGGGAEVDGFSKTLSSLDISIQTSDFIIIFVLALVLVVLVMALASSNLLRKQ
                     PKELLLDGE"
     gene            complement(28088..28735)
                     /gene="vex2"
                     /locus_tag="VQ865_001254"
     CDS             complement(28088..28735)
                     /gene="vex2"
                     /locus_tag="VQ865_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding subunit Vex2"
                     /protein_id="HET3135588.1"
                     /translation="MTLLQLQDVTYRYKNTAEAVLYQINYNFEPGKFYSIIGESGAGK
                     STLLSLLAGLDSPVEGSILFQGEDIRKKGYSYHRMHHISLVFQNYNLIDYLSPLENIQ
                     LVNKKASKNTLLELGLDESQIKRNVLQLSGGQQQRVAIARSLVSEAPVILADEPTGNL
                     DPKTAGDIVELLKSLAQKTGKCVIVVTHSKEVAQASDITLELKDKKLTETRNTSK"
     gene            complement(28748..30025)
                     /locus_tag="VQ865_001255"
     CDS             complement(28748..30025)
                     /locus_tag="VQ865_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135589.1"
                     /translation="MNPIQRSWAYVSRKRLRSFILFLILLVLLAGISACLTLMKSNKT
                     VESNLYKSLNTSFSIKKIENGQTFKLSDLASVSKIKGLENVSPELETVAKLKDKEAVT
                     GEQSVERDDLSAADNNLVSLTALEDSSKDVTFTSSAFNLKEGRHLQKGDSKKILIHEE
                     LAKKNGLSLHDKIGLDAGQSESGKGQTVEFEIIGIFSGKKQEKFTGLSSDFSENQVFT
                     DYESSQTLLGNSEAQVSAARFYVENPKEMDGLMKQVENLALENQGYQVEKENKAFEQI
                     KDSVATFQTFLTIFLYGMLIAGAGALILVLSLWLRERVYEVGILLALGKGKSSIFLQF
                     CLEVVLVSLGALLPAFVAGNGITTYLLQTLLASGDQVSLQDTLAKASSLSTSILSFAE
                     SYVFLVLLSCLSVALCFLFLFRKSPKEILSSIS"
BASE COUNT         8617 a         6925 c         5600 g         8995 t
ORIGIN      
        1 ttttgcgtgt ttaagttgat aagctgtttt taatacagct aacatctctt caaaagtggt
       61 acgctgaaca ccaacaagac gcttaaatcg tgcatcagtt agttgtttac ttgcttcatc
      121 attcatagaa ctactatacc atattttgtt tcgcaggaag tctgatctca tccggttttg
      181 cttgacgggt ttctgcggtc atttcttcaa aagggaccca ccagactggc ccacgtccat
      241 tgagaccgtg accattcatg tcacctgttc gtctaggaaa cagatgccaa tgaagatggg
      301 catcgccatt tcctagcagt tcgatattca ttttctcagc agcaaaggcc ttggcaactg
      361 cctcttggac cacactcatt tcttctagaa aacggagtct tgtctccttt ttcaaatggt
      421 gcaattccgt gacatgttcc ttggctagaa agagactata gcctgcaaaa tactgatggt
      481 ctccaatcac aagatagcct gtttccaact ctttgacaaa gtagggattt tctcccttct
      541 tgatgagctc aattctctgg caaataaggc acatatcaat ctactaaatt gcttctaaga
      601 taggcatcga ccattcgttc tgttgcgacc accgagtcaa tatgagtgcg ctcataagaa
      661 tgactagact cgatacccgc accaagaagg gcatgcttga cctctgcccc tgcagacata
      721 gccgctgaag catccgaacc ataaaatgga tagatgtcca gcttaaaagg aatatcttgc
      781 tctttagcca aggcaaccaa gtgttgacgg aagtcatagt gataaggacc tgaagcatcc
      841 ttgacacaga tagatactgt gtactcatct gtctgctggt catctcccat agctcccata
      901 tccacagcca gatattctac tacctgagca ggaatgttag aattagcacc atgtcctact
      961 tcttcaaaaa ctgaaaaagc aaaatgagtt gttactggca attcaatctt ctctttctta
     1021 taaatacgaa gcaggttgag caaaatcgct gcgctgacct tatcatccaa atgacgagac
     1081 ttgataaaac ctgtatcagt cacaacagtt cgtggatcga agctgataaa atcaccgacc
     1141 tcaatcccaa gagcacgagt ttctttttca ttgcttactt ttacatccaa acgcacttcc
     1201 atattgtcct gcgtgcgttc tgcagttcct gcatccttgt agacatggca agaagtttgg
     1261 tggatgagga tggttcctga taccttttga cctgtgctag ccacatgaac ggtacagttt
     1321 tcaccttcaa tcatgttcca aggaaaacca ccgatacggt ccaatttaag acgaccatct
     1381 ggtttgacag cacgaacaat agcacccagc gtgtccacat gggcagtcac atagcgatgt
     1441 tgctcatcat tttgaccttt gatggtcaca ttgacaccac ccttggctgt gcgaactggc
     1501 tggtaaccaa aaccttctag agtcttgact aaataattcg aaatttcacg agttaagccc
     1561 gttggcgatg cgatggctgt cagttctttg atatattcta ctgtttgatt catttcttca
     1621 cctctttcgc tacctattat aacacattta tcatcggata aaaaaagaaa atcactcctg
     1681 tagacttggc tacaaaagtg atttaagtga ttattccatt tcaaaaacat cgctttcttg
     1741 cttgtttggt agaaccaatg agagcaagat tccaacaatg gctggcacca accatgggag
     1801 agatgccttg gcaaaaggaa gaacgctaac aagatttgca agaaactcaa ccttaaacga
     1861 gcttcctagt acgcttgcaa tggcaataac tgtaaccaca gcaattgtca actgcatacc
     1921 tggttttgaa agggcaacaa atttgttgac aatgacaatc ataacgatag caatcgtgat
     1981 tgggtacaag ataaccagta ctggaattga gtacttgata atcgcatcaa gacccaaatt
     2041 ggcaatagca aatccaatca aggtaaaggc tgtcgcataa accttgtagc tgatttgtgg
     2101 gaagcgctca ttaaagaact cagctgttga cacaatcaaa ccaacagtcg ttgtgaagca
     2161 ggttacggta accatagctg caaggaagag ttgagctgtt gagccaaaga tttcttgagt
     2221 ggcttgtgac aagatgtaaa cacctggtgt tccacccttc atcgcttcag ctggtactgg
     2281 gaaatgattt ccaagaaaac ctaaaccaat gtaaagagcg ctgaaggcaa gggcaacaac
     2341 gataccaata acccaaatag ttgaaatgta ttctttctta cttgaaaatc caagttgttt
     2401 caaggtttga actgcgatta cgctaaaggc cactgaggca agggcgtcca aggtattgta
     2461 accttctagg aaacctgtac caaaggcaga agcttgataa gcagctgaag cagcttgagg
     2521 acttgttcca ccatatttga tagctcccag aacgaccaag ataacaatca aaattgcaaa
     2581 gactggcgtt aaaatacgtc caatgcggtc taagattttt gatggattaa gcgaaatcaa
     2641 ataggctgcc gcaaaataca gaaccgtaaa tacaatcaag ccaagtcctt tatttgcatc
     2701 cgacaaaagg gggctaatcc ctacttcgta agctgttgta gcagtacgtg gggtagcaaa
     2761 gaatggaccg attgacaagt aaagaactga gaggtaaaga gtcgcaaacc aaggcgctat
     2821 cttcgttgaa atctcgtaga tatatccttt aggatttagc gttccaataa taagggtcaa
     2881 gacggcgata ccaacgcctg aaaagacaaa acctgcgatg gcaggaagaa aatgttctcc
     2941 agatagagca cctagagaag gcggaaaaat caagttcccc gcaccaaaaa atattccaaa
     3001 caggagcaaa cctgttaggg tacctttttt agccataaaa atctccttca tatttataaa
     3061 atactgacct agtataccac gattaggagt ctgaaaaaag catcacgagg caaatattaa
     3121 atgttttcaa ttttcttaaa aataagaatt atctaaaaat aaaactctcc tacccagtcc
     3181 acaccaagta ggagaaatgc aaaattttaa agttcttcaa aggctaacat gccaccctgg
     3241 acattgataa cattataacc ttgttctaac aggaattggc aagcacgcgc cgatctcatt
     3301 ccagatttgc aaataatata atgcaagcga tctttgtcca attaatcata actatcagcc
     3361 aattgactaa gcggtaggtt gtgggcacat tctaaatgaa gagctgcaaa ctcatccact
     3421 tctctcacat ccactagaga aagctggtcg ttttggtaaa gctggtaaaa tgcgtcaaag
     3481 gctatttctt tcattctttt tcttctaata ctcttcgaaa atctcttcaa accacgtcag
     3541 cgtcgcctta ccgtgcgtat gttaccgact tcgtcagttt tatctgcaac ctcaaagctg
     3601 tactttgagc agcctacgac tagcttccta gtttgctctt tgattttcat tgactataaa
     3661 atggttttaa ttcttttttt caaatctggc actacttctg cctcaaacca aggatttttg
     3721 gccatccaga tttgatttcg tggtgatggg tgaactagcg gaaaataggc tggcagatag
     3781 tctttatagt gtttcaccct ctccgttacc ttcccactga ttttctcctg taaatagtag
     3841 gcttgggcat attgcccaat caagagggtt aactgaatat caggcaattc ctgtaagagc
     3901 tgcggatgcc atttttctgc aaaacctgta cgaggcggaa gatcacccga cttgccatgt
     3961 cctggaaagt agaaatccat aggcaaaaca gcaaaataac ctgaattgta aaaggtatct
     4021 tcatccacac ctagccagtc ccgcaagcgg tcaccacttt tatctttcca gtaaaggcct
     4081 gcttcttgag ttttaagtcc cggagcctga ccgatgatat tgatgcgagc agtttttggc
     4141 gctgcaaaga gaggctcaat gccacgctct gtatagctgg cattctgtga atccgccatg
     4201 atagcctgtt tgattctttc gatttgagac atctactttc cctccaaaaa gaagtccaag
     4261 cataagatct cagacttcta tcgttttatt tgatcaattc gtaaatagct tcggcataaa
     4321 ttgctgctgc tcggaaaaga tcatccaagg cgataaattc attggcttgg tgcatggtat
     4381 caatcgagtc tgggaacata gcaccgtagg caactccgcg ttctagcaag cgaccaaagg
     4441 ttccaccacc gatgacttgt tcatgacctt taaggccagt ttgtttttca tagatattca
     4501 acaaggtttg cacaagtgga tcttccattg gcacatagtg aggcgtgtga ccgtgttcag
     4561 acaggctaac agaaacaact ggcaagtttt caaggattga cttgatttgt tctggacttg
     4621 ttccttttgg atagcggatg ttgagggcaa tggtattatc agcacttgtt tcatcgaagc
     4681 ggaagacgcc ggcattcata gaaagagcac ccatcttttc atccacatga gcaatcttaa
     4741 gattttcacc ctcatgatcg ttcaagagaa ttttacctgc gatgtcaagg tagtctttgg
     4801 ctggaccagc aaagccaaac tggctgagga agagggcaag gtaagttgcg ccattgacac
     4861 ctgaagcagg catagcaccg tgggctgatt taccaatgat cgtcaccttg tatttgccag
     4921 cttcttcttg gagttctcct ctaagtttgt gttctgcaac aaaggcatct agtttagctt
     4981 gcaagtcagc caaatcacct gaaacgactg ctgttgctga ttctggtacc atattttcac
     5041 gtaaaccacc tgtaaagctg tgaagacggg cagcacctgt attttctcct gcaaagtgga
     5101 ggtattccgt gatatttcct ttttcaccat tgatgattgg aaattcagca tctggagaga
     5161 aaccgaaatc tggtttggca agtcctacgt gctcaaagta gtagtccatg tctgcccagc
     5221 ctgattcttc gtctgttcca acgatgaagc gaactttctt agaagttgga agacccaatt
     5281 ctttgatgat tttcaaacca tagtaacaag ctgttgtagg acccttatcg tccgaagccc
     5341 cgcgcgcata aaggcgacca tctttgatag ttggtgtgta aggatctgtg tcccaaccgc
     5401 taccagcagg caccacatcc atatgggcaa agattccgag aacttcttct ccatcaccaa
     5461 actcaaaatg tcctgcgtag ttatcgacat tcttagttgg gtagccatcg cggtctgcga
     5521 tttcaaggaa tttctccaag gcttttactg gaccaggtcc aaatggatgc tgggcatcag
     5581 ccttgctatc atcacgttct gagttgattt ccaaaaggct aaacaagtca gccaagaggt
     5641 cttctttgcg tttttctact tctgctgtaa aatcaattgc tgtcattttt tcttctttct
     5701 atcttttctc gatgatttca tctactggca agcggtagct tggttccaat ttgtcgtctg
     5761 tgtaacccac tgtgatcaag agttctgggc ggaaacggtc ttcgatttcc aaaacttcat
     5821 taacttttga tttgtcaaaa ccaaggataa tattggaacc aattccttgg tctgtaagag
     5881 cgagaaccaa gttcatagca accaaacctg cattgagtgc taggtagtcg ctgacttgtt
     5941 gttcattgta gcgtgcaaat tcagctggca aatttttcat gaagtattga agttgctctt
     6001 cagaaaagtt attagcacca ccaacacggg caatcttacg agcacgtttg gctaagtccg
     6061 tatctgtaaa caaggcaatg gttacaggcg ctgatgatac ctgttcaaaa ttggaaccat
     6121 aagctaactt tgccagttca gcatttttct cacgtaccac cacaaatttc caaggctggc
     6181 tgttgtgggc gcttggcgcc aaggttgcaa tttcgatagc cgtacgcaca tcttttggat
     6241 caacaggctt atcagtaaaa tgcttagtcg catgacgttt tttatttaat tcaagaaatt
     6301 tcataatcga tttccttttc taattctact gcttccattc taccataatt tgaaagagct
     6361 tgcagggatt tttcatgatt aagtttttct atcacagaca taaaagatat atattggttt
     6421 atcaggaaca tttctgataa actagcaagt actttacatt tgaatggaga cagtatgaaa
     6481 aaatttagcc tattactagc tatcctacca tttttggttg cctgtgggaa tcaagctaca
     6541 cccaaagaga ctagcgctca aaagacaatc gtccttgcta cagctggcga cgtgccaccg
     6601 tttgactacg aagacaaggg caatctgaca ggcttcgata tcgaagtttt aaaggcagta
     6661 gatgaaaaac tcagcgacta cgagattcaa ttccaaagaa ccgcctggga gagcatcttc
     6721 ccaggacttg attctggtca ctatcaggct gcggccaata acttgagtta cacaaaagag
     6781 cgtgctgaaa aataccttta ctcgcttcca atttccaaca atcccctcgt ccttgtcagc
     6841 aacaagaaaa atcctttgac ttctcttgac cagatcgctg gtaaaacaac acaagaggat
     6901 accggaactt ctaacgctca attcatcaat aactggaatc agaaacacac tgataatccc
     6961 gctacaatta atttttctgg tgaggatatt ggtaaacgaa tcctagacct tgctaacgga
     7021 gagtttgatt tcctagtttt tgacaaggta tccgttcaaa agattatcaa ggaccgtggt
     7081 ttagacctct cagtcgttga tttaccttct gcagatagcc ccagcaatta tatcattttc
     7141 tcaagcgacc aaaaagagtt taaagagcaa tttgataaag cgctcaaaga actctatcaa
     7201 gacggaaccc ttgaaaaact cagcaatacc tatctaggtg gttcttacct cccagatcaa
     7261 tctcagttac aataacactc ttcgaaaatc tcttcaaacc acgtcagctt tatctgcaac
     7321 ctcaaagctg tgctttgagc aacctacggc tagcttccta gtttgctctt tgattttcat
     7381 tgagtataag atatactaaa agcgattgga ccagccaatc gcttttttag tttgcattgg
     7441 ctattttagg aaactcttac aaaaaatcaa aaaaattctt cacatcctct acatacccat
     7501 gcttttctat taagctggct aataattcca gattgtgccc ctgatagtta tcgtcacgac
     7561 gcagttcttc atacatttcg ataaagggaa gccccttgga cttggccaat tctaactcag
     7621 cttcgtaatc ataagcaact ttacgaaatt ggatattgag taattcccca tcttcaactt
     7681 ctatcacggc atactgggca cggtgatttt ttaacgcctc ccaattaaaa tagggcatgc
     7741 caatcgaccc tggattgatg atttgttgcc cttgacttcc ataacgaagc aactgcttgt
     7801 gaacatgacc ataaactgcc acgtccgttt ccgcatctag caagtcacca ccatagtttt
     7861 tgtcaggtaa attatgagag atagaaaagc gcaatccgtc aatttctttc ttttccagca
     7921 aaggcaagct tcgtagccag acaatcgttg caggatccat tcgctccatc aaatactgtg
     7981 tcatacgcaa gagctgaact tcctgtgggt cttctaagcc atattgccca tctaaagcct
     8041 caaggacacg atcatcccaa ttgcctcgaa cacttgctgt gataggaagg tcctttagca
     8101 gggcgactaa gtcatttgcg cctggaccag gaagaaaaat atctcccaga agccaatatt
     8161 cactggcccc ttgattttta gcatctgcaa tcactgcttc tagcgccgtc gcattgccat
     8221 gaacatctga taaaattgcg attttatggt tcattgtggt ttccttccgt ttggtaatct
     8281 actctttctt ctgctacttg aggcaaggct tctccctgcg ggttcaactt tctttgcaca
     8341 gcctctgcaa cgactctagg taccccaact tcgacaatct catccacact ggcttccttg
     8401 attttggtca aagacttgaa atgcctcatg agattttgct tgcgtttagg tcccagacca
     8461 tcaatcccat ccaattgaga tgagaaagaa tttttggagc gcagttggcg gtggaaagtg
     8521 atagcaaagc ggtgcacctc atcttggatg cgttggagga ggaaaaattc ctgagaattg
     8581 cgagacaagt ccaccacctc aagcggatct ccaaagagca attcatgggt ttggtgctta
     8641 tcattctttt gcagcccagc aattggaata tccaagccca gttcctcttg gataacctgc
     8701 ttagcgatat tgacttgacc ttgcccccca tcaatcacaa tcaaatctgg aggagtcaaa
     8761 gcctcacgct gtactcgacc atagcgtctg cgaatgacct ctctcatgct ggcatagtcg
     8821 tctggtccaa caaccgtttt tatcttgtac ttacggtaat ccttcttact cggtttaccg
     8881 ttgacaaaga ccaccatagc cgaaacaggg ctagttccca tgatattaga gttatcgaag
     8941 gactcgatac gtactggggt cgggatttgg agcaaacgcc ctagattttc aatagctcct
     9001 tgagtctttt cgacagattt ttctagcaga ttgaacttct gctctagact aacacgagca
     9061 ttttttatgg ctagattgac cagttgtttt ttctctccac gttgaggctt aagaatcttg
     9121 gaatccacca aggccttgac agcctcttcg tcaatatcct gcggaatcag tacctcattg
     9181 ggaactagat gagatttttc ttgatagaat tgtcctacat aggtcaaaaa atcctcatct
     9241 ggatcattga agtaggggaa gagattgaca tcgcgctcga taagcttacc ctgacggaca
     9301 aagaaaacct gcacacacat ccagccctta tccacatagt agccaaagac atcgcgattt
     9361 tgcaaatctt tcgccatgac ccgttgcttg gttcgaagcg ttccaatagc ctgaatcagg
     9421 tcacggtatt ccgccgcacg ttcaaactcc atactttgtg ctgctactgc cattttactc
     9481 ttgagatcat cgatgatttt gtcatcctga cctttcagaa aatcagacac ctcctgagcc
     9541 atagacttga aataagcctc atccttctta cagatggtgt gggccataca ctggccgata
     9601 tggtaataaa aacagacctt agagggcggg ttggtacatt ttcgaaaagg gaaaatccta
     9661 tctagaagtc gcttgatttc attggctgcc cccacatctg gataagggcc aaaataaaga
     9721 ccaccgtcct ttttgacctg acgagtaatg ataagccgtg gatagcgctc attggtgatt
     9781 ttgatgaaag gataggactt gtcatccttg agcatgatat tgtacttggg cttgttttcc
     9841 ttgatcaggt tgatttctag gagaagtgcc tcaatattag actccgtaac aataaattca
     9901 aaatccacaa tttcagacac cagagcctct gtcttggtat catgacttcc acgaaaatag
     9961 gaccgtactc gattacgcag atttttagcc tttcctacat agataatggt gccattttta
    10021 tccttatgaa tgtagcaacc agggctggtc ggcaagagct ctagttttga tttaatcaag
    10081 ttgttcatag ttccattata gcaaaaaaag tagggaaaga tagtacccta ctcactagtc
    10141 tcatatattt ttcggaggtt tgcaacatcc tcttcctgga taccataaaa ggaacctgct
    10201 ggttgcatga cagacttctc atctgtatgg tccaagccaa tcgcatgacc taactcatgt
    10261 tctgccgtat ggacaaggcg ttcataggag tagccatagt atggattgga caaataataa
    10321 tgattcaacc gcaccgttac ggacaagaat tgccctgtta agagattagt ttgactttcc
    10381 gcctctcctg ccacaggagt gcctccgtcg ttcatctccg tagccgtaat atccgcctta
    10441 ctagactcag tcacgagttc aaagttaaaa gcaccagttt gattccagtt ctggattgct
    10501 tctaaataag cctcttgaaa gcgtgaatcc atctgcggat ccaggtaaat acgagcagag
    10561 gcctgtgccc accttccttc agaatgctgg tgactatctg tctggcttaa cttaggcagt
    10621 tgccctgttt tctcccattg gtcaatactt tgttgaccaa tttttactga ccgttctgct
    10681 tgctttagcg ctccttgaaa atccccgttc agataccaga gaagtccgaa agcaagcaca
    10741 cataagagca caactatcca aaccagacgc caaaacaaac gccacacaaa agaaaagaaa
    10801 gcccctatca aacgaaaaag ccagcgcatg tctctccacc tttctagcaa ataagaatta
    10861 ttttactaaa agaagctaaa agaaatctaa atactgactt tttcatctta acgtcctact
    10921 atttttttga gtaactggat agctttgtat tttaaaggcg atggatggta acggaaagta
    10981 cccgctttgc gtacaatata gccattaaaa ttctgtttaa aacgcaaaac accatcactt
    11041 ccatcaaaaa tcccttgaat gcctaggaag ttgtatttag gtattccacg ttttatgctt
    11101 tccaacataa catatttttg aagcagggca ggggcataga acttattaaa ctcagtgtag
    11161 gaaccactaa agagataagt cgtttcctga ggcatataaa caaataaact cccagctaaa
    11221 acaatatctt cttctccata tttttcaatc aagtctcgcg cttctgcttt tcgaacttca
    11281 aacgtttcaa attgactaga atattctctc agttgatttt gttttttctc agaatgagga
    11341 tttttactca aatcaagtcg caacttgtcc aagttttctt ctagtttact ttgttcacct
    11401 tgcaatttgc tcatatagtc cgaaaaattt aagcttgcta tgagaaactc cgcttgttct
    11461 ccaaaagtat cataaaaatg ctcataatat tctaaacttt tatcactata ttctctacgt
    11521 tcagaggttt cttttgttat attcttaaaa atcgatagtt cttcacgttt taactttttc
    11581 aaccgaatgc caaaggtttc agcctttttc accaagggtt tacccttttt gctaaaactt
    11641 ttaagcaaac tcttttcagt taattcagtt aaatctttat agtataacca atctggttct
    11701 ccacctgggt aacctgttgt taagccatca aattgataac ctaaatcagt caaaccttga
    11761 ataatacttt ttttctcagc atctattgga ttaccttggc tatcaaaagt ttgataagtt
    11821 tcataaggtt ttacaagcaa ctctaataca ccattttgct tggcatattc ttttaactct
    11881 gcataaaaaa ctggaagagc atcttgttgg gtataaatcg gccccgaatt gagttccata
    11941 tgcagaccac ccagcatggg caagctataa accagagctg caacttgaat ttctccttct
    12001 tgtttcaaag caagataaac aattcgagcc cctctttttt ctagcaaatc ccccatctgg
    12061 acagattgca taaaggaacg agaagaaacc tgatcagaat aagtctgaaa ctcttctttc
    12121 gtgagtgttg ttagtgccat atacttactt tctatgtttt tttcttaatg ttttacggaa
    12181 atcaagagca agtcttaaca gaggatagag aggatgagtg ggcattgtaa attcacccaa
    12241 gtattcttca atcgttggat taaatttttc cttaaaatga taaagtccac cattgagaga
    12301 gttttcaaca ccacctaaat tttgccaaac catacctcgc tcaaaggcat agcgagccgt
    12361 ttcataccat gttaaaattg gtgcattgta acgtttaaaa tcatcatcca taccagcata
    12421 tatattgaca gaggtagtac caaattccaa actcaaagta gccgctaaag gaactctcgc
    12481 ttgacctaca tctatatatt cctgcaagaa ggtcaattcc tctaacaaac gttctttttc
    12541 cttcttctgc gcttctactt ttgaaattcg agtcgactca gtaaaggtct cttccaaggc
    12601 tctatttttt gctaactgtt cttctaattc ttgcgaacgt ttagaaacat ccaaggtggc
    12661 caaggtgata taggccttgt ccttaaaatt atctaacaat tttttataat aggcttcatt
    12721 cctcaaatga atctcttttc gcttctcagt ttttttcatc aactccgaaa atgaatctaa
    12781 tagttccagt ccaccatatt gaatctcaag ccctttgttt cgtgctgttc gaatagcctg
    12841 ttttgttgac ttggaaagtt tatcttcttc aaaattttcc ttgtatattt tcgcctgaat
    12901 acgaggttga atggtgtctc ccatttcctc cgtttttcct gaccacctta ctcccatttg
    12961 ttgcaaacta tcaataatag ccagattttc aggaaattct gtcttttcct gattgattaa
    13021 actttgagat aggcaaatac ttgggtcaaa agtcacaaaa accgctctct tactgcgagc
    13081 ataggactta atagactgaa tgacaaaatt caagagttct ttatccccat aatccaatat
    13141 aggtcctctt gggatgtaaa acattttata gcctagcgga agagttctaa tcaaaatact
    13201 agctgtcgcc agtaattttt cttccctgta aacaccaaac ttctcatgtt gccaattaga
    13261 cttaacttcc tcccaagcac tactttgtaa tacattggct aattcatgtt ctttgacaaa
    13321 ctgatcatat tctaatgtgg gaatgccaat ttgataacgg tacatttcct actctctttc
    13381 ctccagtatt ttattactat tctactactt tcgtttgaaa agtctagtga aaacatattt
    13441 tattttagtt ctactccccc tatgctgaag ttcaaactaa gtcagtctct cttctaattt
    13501 gaaatcaatt ggtagggttg ttaaaaaaac ttccaattgt ttttcccagt agtaccactc
    13561 gtgagttcca gcgctatggc tataggtcac atcaaaacct agttttttga gatttttcac
    13621 tgcgagatta ttggcttcgt acaagaaatc ctgttcgcca caccacgccc aaagtttggt
    13681 ctttttatcc gattttttag ccagactttc aagagaatag ggactagttg tccagtcttt
    13741 aatctctcca aaaacacctc tccagtaggc tggacttccc agattttgac tttcaggaga
    13801 aaagttttga aaactgaggg cacctgaaaa gctagctgca tgagaaaaac gatttgtcgc
    13861 aagagccagt ttgaagcagc cgtagcctcc catagaaaga ccagcgataa aggtcttttc
    13921 acgcttgcta gtcatattag ggaagaagcg tttcagaacc tgtggcaatt cctctgctag
    13981 agccgtgtag tagtcaaaac catactgggt atcggtgtac caaccattgc tggtattggg
    14041 cataacaacg atgagattag ttcctcgaag caagcgttct acattggtcc gcttaagcca
    14101 actattatga tttccagaca tcccgtgcaa aaggtacaag acgggaatat cttcacactc
    14161 tggttcttcc actcgattgg catcagggta gaggacattc accccccact ccatatccaa
    14221 tacttgtgag taatactcga ttttcattac tgccatgatt ttctccttct atttttctat
    14281 aagaaaaagc cgaaactcga ctttctctct gtttatttca acgattattt tgcttccatg
    14341 actactggta aaatagctgg acgacgcttg gtttggtcaa agagatactt ggtcaaatta
    14401 tctcgaacct tccctttaag atctgcccag tcaaagtcat ctccttgaag atactcttct
    14461 accgtttggt taatcaattc tgaactttca tggagaatat cgcgactctt cttgagataa
    14521 acaaatccgc gcgtatgaac acgagcccta gccacaattt tcttctcacg acggttgact
    14581 gtaatagcca cgatgaaaat tccatcctct gacaagacct tacggtcacg aagaacaaca
    14641 tttccaacat caccaatggc attcccatca atcaagatat ctcctgctga aaccgatcca
    14701 gctggaacaa agtctccatt ctcgtaagcc atggtcgtcc cctttttagg aatgaagatg
    14761 tgttctggca acatcccaac tgccatggca gccttagcgt gagcatccaa ctcacgatac
    14821 tccccttgga cagggaagag gtacttaggt tgcaaaagat tgatcatcag ctgcaaatca
    14881 cgcacatttc cgtgccctga tacatgtaaa ctttgggtaa tcaatttgac aaccccacct
    14941 gcctgataaa tcatattttc cacacgcgca acaaaggctt ctttagcaat agacggagcc
    15001 gtagcaatat agaccaggtc cccatccttg atttctacat aacgatggcg accaatcgac
    15061 atcttacgaa gtccattgat aggttcaccc atacgacctg tctcaagaat aatcaactca
    15121 tggtcttcaa agcgagacat atctttaggc ttaatcaaga gaatttcgtt ggctaaagac
    15181 aacttcttaa gacgaatcgc tgtgcggacg atattttcaa tatcaaatcc tgtcaagacg
    15241 atacgtcgac ctgttttatc cgcagcgtca aaaatctgct gaatacgaga aagattactg
    15301 gaaacagctg caacgatgat acgaccttcc cagtcagcaa tagtttgggt aatttcatcc
    15361 ctaacttcac tttcactagc cacctgaata ttgctgtctg cattggccga atcactgagg
    15421 agagccagga cgccgtcacg accaatctct gccaaacgag caaaatcagt tgcataagat
    15481 tcactagccg tttggtcaaa tttgaaatca cctgtataaa cgatgcttcc ttccgatgtc
    15541 ttcaagacaa ttcccagact ctctggaacg gagtaagtcg tagggaagaa ggaaaccact
    15601 gtcccaccaa aatcaatctc cgtattctca tcaatgacat ggaaatcatt aaatttctta
    15661 acggcatcat ttcctttgac aaagagcttt gccaactcaa tggtcaactc agacccaaat
    15721 acaggaactt tagcctctgc caagagataa ggtagagcac caatggcatc cgcatgcccg
    15781 tgggtcaaga aaaccccagc aatacggtcg ctattttcaa aaaggtaatc catgtttgga
    15841 atcaccacat cgacccctaa ttgttcattt tcaggatatt ttaaccctac attcaaaaca
    15901 aaaatggact ctccaatttc agcaatgtac atattttttc cattctcacg cacaccacca
    15961 agtgttgtta aactgatatt actcattttt cctccaaaat cttagtttat cttgattata
    16021 gggcaactct accctcttat tctaaaagtt ctaatacttt cagccgaatc ttttcctacc
    16081 attataccat ttttttgatg attttcaaaa tgaaggtctg ttttcaaaaa agagttgatt
    16141 tcccaactct ttcctaactt ctactctttt tccatcaaaa aatcataaat ttcttgcacc
    16201 gtacccagcg ccatcatttc ttggtcttta acggtttgtt tgagattttg gtaaatttga
    16261 ctttctccta tctcccgctt tggcgcctct ttattgactg tcatcacacc atcttttatc
    16321 gtcacaaagc ctagttcttc aaatacttga atcatcttga ccagcaagat ttgttgaata
    16381 ttaagatatg cagccaaatc tttcagcttg tagcgaatat caaactctgg gaactggtaa
    16441 atagtcttgt acaatttggc aaactgatct ctagtcccat aacctgtcag ataataggcc
    16501 ttgtcaatat catttttgaa atagacagca gagaaatgct gttcctgaaa aatggtcttc
    16561 agctgagtaa tatcctctgg aatgtttttt acgacaatag cttcactagc cgcaagattt
    16621 ggcagttctc caggaaaatc caagactgga acaccttctg gcaagactgc attttttcca
    16681 cgaatgttaa aaagttgaac accttccact cgcgcatcca ccatcatcaa ctggagggca
    16741 gtttggccat tccattggtt gacagacaat ttaaccgcta actctagatt cttggtttga
    16801 gaaaactctg tcgcccatct gccttgacca aaggctacca cttcaaaact cgcctcaccc
    16861 ttggaaattt tcagctttag atgggcatta cctgccccca tagtacgagc actttcgacc
    16921 tgaaaattct tgatataaaa aataggtttc tgattatcca ttccaaaagg agctaaacgt
    16981 tcaaaacttt tgaccgtttc caagctaagt gcctccaaat ccaactcttc atctaggttt
    17041 aacttattct tgccaccagc atctgcacct ttttcacgaa cataatcttc caaaacctga
    17101 gataaatctg agagttgctc aacttccagc gtcatacccg ctgcacctgc atgacctcca
    17161 aaggcgatga agaggtctcg atggggatcc agagcttcaa aaatatcgac cgcttccaca
    17221 ctacgagcac tgcccttggc acgaccgtct tctatattaa gaacaatgac tgtctgtccc
    17281 aattcttcca ataaacgacc agccacgatt cctagaaccc caggattcca gccttccttg
    17341 gccaagacct gaaccttctt ctcaggatcc accatggtct tggcttcttc atagatagac
    17401 tgaacgattt ccttgcgctc ttcgtttttc tggtgaatca taagggcaat ctcatgcgct
    17461 tcctcatcat caaatccagt caacaaatca atggcaggat tgggatcatc caagcgaccc
    17521 aaggcattca aacgaggagc aatctggaaa ccaaccgttt cttctgttac ttcgttggca
    17581 gcaatcccag ccatgtccag catttcttgc agaccaatgc gctgggtatg acccaacatt
    17641 tccagaccat attgaactaa gatacgattt tcatccgtca gactcaccat atctgcaata
    17701 gttccaatag cgaccaaatc aagcaattcc acttgcactt cttctaacag ggcacaagcc
    17761 aacttgaaag caactccaca accagccaaa tatttaaaag gataatccgc atctggatgt
    17821 tcaggatgga caatagcata agcatctggc agggtttcag gcatggaatg atggtctgtc
    17881 acaatgacat ctactcccat agactgagcc aatgcaatag cctcatgacc agcaacccca
    17941 ttgtccaccg tcacaatcaa ggaaattcct tcttgctcga taaagtattt ataaacacta
    18001 gcattagggc catagccatc ggtaaaacga tttggcaggt aaactcggca ctccgcacca
    18061 agttgttcca aactttcctt cacaatagaa gccgaagtca tgccatccgc atcatagtct
    18121 ccataaacga gaatattttc cccttcttca atagcctgac gaatccgctc cactgccttg
    18181 tccatatcat ggagcagata agcatcatgt aagtcctcca aggaaggttc taaaaacttc
    18241 ttcagacttt cttggtcctg aatccctctc tcaaacaata accgagccac ctcaggaccc
    18301 agtccagcct tcttggctat ctttgtaaaa tccgcatctt ctacctgcag ggcaaactgc
    18361 cattcataag taggtgttat caaaaagaca tccactcttt ctaagaattc tattgcttca
    18421 ttataacatg atttagacgt tttctctatc cagattgctt ttttataaca ttttatagta
    18481 tattgaaact agaatagtac acctctactt ataaaatatt gttagaaatc gatttgactg
    18541 tcccgatcga tttgtccttt tcttatttca ctatagtgaa ttttttcaga tacggtttga
    18601 caagaacatt cttttattgt agaattgtgt tataaaatct aatataaagg agatctctca
    18661 tggctttagt agaatttaaa aacgtcgaaa aatattacgg agactaccac gcactccgca
    18721 acatcaatct ccgttttgaa aaaggacaag ttgttgtcct gcttggacct tctggctctg
    18781 ggaagtccac tcttatccgt acgatcaatg gtttagaggc tgttgacaaa ggaagtctcc
    18841 tagtcaatgg gcaccaagtt gctggtgcca gccagaaaga tttggtacct cttcgcaagg
    18901 aagtcggcat ggtttttcaa cattttaacc tttatccaca caaaacggtg ttagaaaacg
    18961 tgacacttgc gcccattaaa gttctaggaa ttgataaaaa agaagctgaa aaaaccgccc
    19021 aaaaatatct ggaatttgta aatatgtggg acaagaaaga ttcctatccc gccatactat
    19081 ctggtggaca aaaacagcgg atcgccatcg ctcgtggtct tgctatgcat ccggaactcc
    19141 tcctctttga tgaaccaaca tctgctcttg atcctgagac tatcggagat gttctagcag
    19201 ttatgcagaa actggcgcat gatgggatga acatgatcat cgttacccac gaaatgggct
    19261 ttgctcgaga ggttgcggac cgcattatct ttatggccga cggagaagtt ttattagata
    19321 cgacagatgt cgataacttt tttgacaatc caagcaaacc tcgtgcccaa caattcctca
    19381 gcaaaattat caaccacgaa agtgacaaag tcaaataagg aggcgcctat gaaaaaaaaa
    19441 ttctttttat cagcattatt gattagcctt ttcggccttg ctgctgccaa accagtccag
    19501 gctgatacta gtatcgcaga cattcaaaaa agaggcgaac tggttgtcgg tgtcaaacaa
    19561 gacgttccca attttggtta caaagatccc aagaccggta cttattctgg tatcgaaacc
    19621 gacttggcca agatggtagc tgatgaactc aaggtcaaga ttcgctatgt gccggttaca
    19681 gcacaaaccc gcggccccct tctagacaat gaacaggtcg atatggatat cgcgaccttt
    19741 accatcacgg acgaacgcaa aaaactctac aactttacca gtccctacta cacagacgct
    19801 tctggatttt tggtcaataa atctgccaaa atcaaaaaga ttgaggacct aaacggcaaa
    19861 accatcggag tcgcccaagg ttctatcacc caacgcctga ttactgaact gggtaaaaag
    19921 aaaggtctga agtttaaatt cgtcgaactt ggttcctacc cagaattgat tacttccctg
    19981 cacgctcatc gtatcgatgc cttttccgtt gaccactcta ttctatctgg ctacactagt
    20041 aaacggacag cactactaga tgatagtttc aagccatctg actacagtat tgttaccaag
    20101 aaatcaaata cagagctcaa cgactatctt gataacttgg ttactaaatg gagcaaggat
    20161 ggtagtttgc agaaacttta tgaccgttac aagctcaaac catctagtca taccgcagat
    20221 taaggaggat accctatgac agatttatca tcttggacag cctattttca ggattttgga
    20281 caatttttca atggtttcct ctttactctt gccctagcga ttggatcctt tatcctcgcc
    20341 atggtcttag gaatcttctt tggtgccatg tcaaccagta aacgtccaat tttacgcatt
    20401 ttagctcgca tcttcgtgga attttaccaa aacactcccc tcttggtgca gtttgttatt
    20461 gttttttatg gcctacctct tatcagtgac cacatcatca tgattccaat ttattggaca
    20521 gccgttctct gcgtgggact ctatcacggc gcttatatcg ctgaggttat tcgttcaggg
    20581 attcagtcta ttcctagtgg tcagatggag gccgccttgt cgcaaggttt tacctatatc
    20641 agtgccatgc gcttgattat cttgcctcag gccttccgca tcattctccc tccattgacc
    20701 aaccaaattg ttaacctcat caagaacaca tctactgtag ctatcatctc tggagtagac
    20761 ttgatgtttg tgactaagtc ttggtcggct ctcaacggaa actatatccc agccttttta
    20821 ggtgctgctc ttctctactt tgccctatgc ttccctgttg cccagtttgg tcgcaagatg
    20881 gagcaagcca ataaaaaagc ctattcactt taggaggtta ctatggaatc tattttagaa
    20941 attttaaccc cagataacct agtctttatc tttaaaggat ttggcttgac cctctatatt
    21001 tctctgattg ccatcatcct ctctactatc atcggtaccg tgcttgccgt catgcgaaat
    21061 ggaaaaaatc ctatcttacg cattatttcc agtatttata tcgagtttgt gcgcaacgtt
    21121 cccaaccttc tctggatttt tactatcttt ttggtgttca aaatgaaatc cacaccagca
    21181 ggtattacag cctttactct ctttacatca gcagccttgg ctgagattat tcgaggcggt
    21241 ctcaatgccg tagacaaggg acaatacgaa gcaggaatgt cacaaggctt cacctcagcc
    21301 caaatcctct actacatcat tctcccacaa gccatccgca aaatgctacc agccatcatt
    21361 tctcagtttg ttaccgtgat taaggatacc agtctcctct actctgttat cgccctacaa
    21421 gaactctttg gagccagcca aattctcatg ggccgttatt tcgaaccaga gcaggtcttc
    21481 agtctttaca tcctgattgc cctcatctac ttcagcttta acctagcgat ttctagcctg
    21541 tctcatatgc tagccaaacg ttggcaacaa gctgcagaat aatactcttc gaaaatctct
    21601 tcaaaccacg tcagcttcac cttgccgtac tcaagtacag cctgcggcta gcttcctagt
    21661 ttgctctttg attttcattg agtataaaca gccactctcc agttcaattg gagagttttt
    21721 tgatgagagt agatatttat agacctcaat ttgacaccat acattttcta tgataaaatg
    21781 taacaaattc atttacaaca aatcgaaatc taaatgaaat ggaattttct atgaaatcag
    21841 tcaaaggact actctttatc atagctagtt ttatcttgac tcttttgact tggatgaaca
    21901 cttctcccca attcatgatt ccaggactag ctttaacaag cctatctctg acttttatcc
    21961 tagccactcg tctcccacta ctagaaagct ggtttcacgg tttggagaag gtctacaccg
    22021 tccacaaatt cacagccttt ctctccatca tcctactaat ctttcataac tttagtatgg
    22081 gcggtttgtg gggctctcgc ttagctgctc agtttggcaa tcttgccatc tatatctttg
    22141 ccagcatcat ccttgtcgcc tatttaggca aatacatcca atacgaagct tggcgatgga
    22201 ttcaccgcct ggtttaccta gcctatattt taggactctt tcacatctac atgataatgg
    22261 gcaatcgtct ccttacattt aatcttctaa gttttcttgt tggtagctat gcccttttag
    22321 gcttactagc tggtttttat atcatttttc tatatcaaaa gatttccttc ccctatctag
    22381 gaaaaattac ccatctcaaa cgcttaaatc acgatactag agaaattcaa atccatctta
    22441 gcagaccttt caactatcaa tcaggacaat ttgcctttct aaagattttc caagaaggct
    22501 ttgaaagtgc tccgcatccc ttttctatct caggaggtca tggtcaaact ctttacttta
    22561 ctgttaaaaa ttcaggcgac cataccaata atatctatga taatcttcaa gccggcagca
    22621 aagtaaccct agacagagct tacggacaca tgatcataga agaaggacga gaaaatcagg
    22681 tttggattgc tggaggtatt gggatcaccc ccttcatctc ttacatccgt gaacatccta
    22741 ttttagataa acaggttcac ttctactata acttccgtgg agatgaaaat gcagtctacc
    22801 tagatttact ccgtaactat gctcagaaaa atcctaattt tgaactccat ctaatcgaca
    22861 gtacgaaaga cggctatctt aattttgaac aaaaaaagtg cccgaacatg caaccgtcta
    22921 tatgtgtggt cctatttcta tgatgaaggc acttgccaaa cagattaaga aacaaaatcc
    22981 aaaaacagag cttatttacg aaggattcaa gttcaaataa gtaatcatac tctcctggga
    23041 tttcccagga gagtttttta tagccaaatg aaataagacc tgaacgatgg aattttggca
    23101 ttcaaatcaa ttgataagaa tattttatag tggagtgaaa taggatacga acaaattgat
    23161 taggaaaatc aaatgaattt atagaaatct tttagcagtt atgttgtcct attctagttt
    23221 cgaaacgcta tagaagcagc attgtgctag tctagattca gtttactata ctaaaacgag
    23281 tagcttggaa tcaaaaaacc caccctcaca ggcaggtttt atctgtatta ttcagctaga
    23341 ttatgcttta ccttctgaac cgaatacgtc gatacgttct tcaaccgatg cttggatagc
    23401 ttttacaccg tcagccaaga atttacgtgg gtcgaagagt tttttcttgt cgtattctgc
    23461 ttcgtttgct tcgtagtcac gagcaaattt acgagttgcg ttagcgaatg cgatttggca
    23521 ttctgtgtta acgttaactt tggcaacacc aagtttgata gctgcttgga tttgctcatc
    23581 aggaatacct gatccaccgt gcaatacgat tgggaatcct ggaagagctt ctgtcaattt
    23641 ttgcaagtgg tcaaggtcaa gaccttccca gtttactggg taagggccgt ggatgttacc
    23701 gataccagct gccaagaagt cgataccagt ttcaaccatt gctttagcgt cttcgattgg
    23761 agccaattca cctttaccga tgattccgtc ttcttcacca ccgatagtac caacttcagc
    23821 ttctactgag atacctttag cgtgtgcttt ttcaacaact tctttagcca atttaaggtt
    23881 ttcttcaact ggaaggtgtg aaccgtcaaa catgattgaa gtataaccaa cttcgataca
    23941 ctcaagtgca tcttcgtagt gaccgtggtc aaggtggata gctactggta cagtgatacc
    24001 cattgattca acaaggttag cgatcaagtt gcgagcaact ttgtaaccac ccatgtattt
    24061 agcagcaccc attgaagttt ggatcaaaac tggagctttt ttagcttctg ctgcgcgcaa
    24121 gatagcttga gtccactcaa ggttgtttgt gttaaatcca ccaactgcat aaccgttgtc
    24181 acgggctgct tggacaaatt tttctgctga aacgattgcc attttatcag gcctcctgta
    24241 tatttttatg ggtcatccca tttacattgt tcattttatc actttttgcc aaaaaaatct
    24301 agtttttccc gcagtttcga ttgattttct tctaactcca tctatgtaaa ccctttctct
    24361 ccctagtctt ggacgacttt tggaaaatct ataaagaagg ttaaacgatt ctcctccatc
    24421 tcgaaacgat aagctaattt ttcatgttct aatagactct taaccacaaa gagccccata
    24481 ccagacccct tgaccttgcg actggcattg tcagaaaaag actgggctag tttttcttgt
    24541 tcctctgagc tacagctatt ttcgataaaa agttctcctt ctctttctcc aattcgaact
    24601 aagccacctg gaacagagtg cttaatggca ttgctgatga gattagaaag aatcaacttc
    24661 ataactgatg ggtttagata agcctgctga tgggtcaaac tattgtctat ctggagctct
    24721 ctttccttgg ctagcaaggc ataatctttg accagatttt gcgtcatctg gaggaggtca
    24781 attgtttccc tatcatctcg caattcctgc acagaagaga gggaaagtat ctgcagaaca
    24841 tggtgattga gttcatccac aatccccaag gcaactccca gatactggtc tctattctta
    24901 taacgaccga tattctctct catattttcg attaggattt tcaaactagc cagcggtgtt
    24961 ttcaattcat gagaagctcc tcgtaggaat tcgaccttca tcttctccag ctggagaatg
    25021 gcttcattct tttcatgcaa gtccgcaata acagtcaaga gatgctggta gaggctattg
    25081 atttgttcct tgagattgcc tatctcatcc ttagaatcca cgcgcaatcg cacttgggaa
    25141 tccaggtcca tcatccgacg ggtcacccgc ttgatttcca aaatcggtgc aacaatagtc
    25201 cgagcgtaga tgtaggccac caagagggaa atcagaaagg aggccagcaa ggtataggga
    25261 agaaactgga gactgatttg ctccgcttcc ttttgtaaat ccatggaagc tagaaactgg
    25321 agaatcatag taccaccgtc ttgcgttttc acctcgcgct cctcaataaa gagagaggtt
    25381 gtctggcggt ctgtgtccag aggaagactg tccttgactt ctaacttgtc ctcggtcatc
    25441 tcacctttga cggtcccctt gatatcacta gtctgggaat acaagtctaa cacttgctcg
    25501 atactctgcc tatctttccc ttctagggac tgggcaatgg ctgttgcctt ttgaccaatg
    25561 gtttcctgac gatgactcag ataagtcgaa ggaaaaagaa aataaatagc taaatgaagg
    25621 cagataacca gaacactaaa tatcgagaag gtatagataa atatctttgt aaataaacct
    25681 gttcgtttca ttttcgctcc aatttataac caacattgcg cacagtgagg atacaatcca
    25741 agtctagctt tttccgcaat tccttgatat aaacatcaat aacacggtca aagggaacct
    25801 catctgtcgc tttccagacg gcatcgataa tctgagaccg agtcaaggcc cggccttcat
    25861 ttttcactag atagtccaga atttccaact ctttggcatt gataggcact tcttgacctg
    25921 cgaggcttgc actgtagctt tcaaagtcca ccttggtatc cttgtaagaa aagattcgtc
    25981 ctgtatcgta gtagcgcttg aaaatcgcgt ccaccctcac ttttaagagg gagagggaga
    26041 aaggtttttc cagatagcca tctgccaaag aggcaaaggc actcatcttg tattcctcat
    26101 cctgaaaagc tgtcaacatc aagacaggaa cctgactggt tttacgaatc tcagctagga
    26161 cttctaagcc gttaagcttg ggcatctgga tatccagtaa aaccagggcc acctcatagc
    26221 tagaaaattg ctccagagct tcctgaccgt ccgctgcctc aatagtttca tagccacaat
    26281 ccgtcaaata atcactgacc ccctcacgga tcatctcttc atcttctaca attaaaattt
    26341 tcatacttta actgctctct attttttatt tttcttagaa taaataccta ctctattttc
    26401 tattatagtc tcttgctggc cttttgtctg taagcaactg accactagat aaaacgttgt
    26461 gaaattcctt tctcataaat tccataactt tagtatatta tatttaagca ctaaagtaca
    26521 aagaaagcaa ctgaaagcaa tgattttcac cactgctttc agatttattt tgaattgtta
    26581 aatagctatt cctatccact attcttgaat agaaacacaa gatgcaatct ttattccaga
    26641 ctcatttttt tcaaatttat tcaccatcca gcaagagctc ttttggttgt tttctaagga
    26701 gattgcttga agcaagcgcc ataacgagaa ccactagaac caaggcaagg acaaaaatga
    26761 tgataaagtc tgatgtctga atggaaatgt ctaggctcga caaggtcttg ctaaagccat
    26821 ctacttctgc accgccacca aggttagagg cttgagccgc cttactagcc tgtttggcaa
    26881 cacctgaagt cacattggca aggacagtgt ttccaattgc acgggcagtg taattagcta
    26941 ggaagtaagc agaaactaga gcagggatag caatcaagat agattcggtg atgaattgac
    27001 ccaagatact tgcctgcttg agaccaatag agaggaggat tcccacttcc ttgcgacggg
    27061 cattgatcca aagactgagc aagagggcaa ggagaaggac tgagaagctc aagctacccc
    27121 agaagaggag gttggccatc ttgtacatac cagagataga ttgctcaaga gctgggtagt
    27181 tagaggagct cttgacgagt gtgtagctct tccagttgat accactgatg ccattcaact
    27241 ctttcataac atcatccaag ttcttgtctg ctgttacaaa gaaggttgcg tccccataaa
    27301 tggctgtgtc ttctgtgtat ccataaagtt ttgcagcagt gtgaatgtct gtaatagctg
    27361 tgttttcgta aagttcttgt gagtaggtta ctgctgactt attatgacca tcaaagagtc
    27421 ccttgattgt cacttcaact gtttccttgg ctcctttttc attatctgca tcgtagatat
    27481 tagagtccag tttaaccttg tcccctactt tccagccgtg tttggctgcc aagtccttgt
    27541 gcaagaggat tttatccttg tcgtcgttgg ttaagtgctc tccttcgact agtttataag
    27601 aaccagagac aaacttatct tctttagagg agtcattgac acctgtaatc atcaagctac
    27661 ttccaaaacg tttggcacga tcagcagtga gattcttctt ggtttctggc gtttcaatca
    27721 ggtcatatcc agtcaaatct ccgatagcgt tgatacgttt gacataagac tcaatggcct
    27781 tgttttcggt gatttttttg atgtcttcac ccttgatatt cccagcacca cgaggcgttc
    27841 cttggttgac gcgacgattg atttgcatgg agaagctatt ggtgatattt ttaaaggtct
    27901 cctgagaagc cttggcagta gctcccttga ttgacaagcc gaccaaactc aagctcgcca
    27961 taaggagaat aatcaggaag atgacaatcg atttgaaaaa cttccttgta acataggcaa
    28021 atgcgttgtg taacatagat tccctttcta gattttgttt taatcattct atcaaaataa
    28081 gctcaaatta tttactagta ttgcgcgttt cagtcagttt cttatccttt aattcaagtg
    28141 taatatctga cgcttgtgcc acttctttac tgtgagttac gacaatcaca catttacctg
    28201 ttttctgggc aagtgatttg agtagttcga caatatctcc agcagtttta ggatccagat
    28261 ttcctgttgg ctcatcagct agaataactg gagcttctga gaccaaactg cgagcaatgg
    28321 caacacgttg ctgttgacca cctgataact ggagaacatt ccgcttaatc tggctttcat
    28381 ccaaaccaag ctcaagaagt gtattcttgc ttgccttttt gttgaccaat tggatatttt
    28441 ccagcggaga aagataatct atcaagttat aattttgaaa gaccagggaa atatggtgca
    28501 tgcgatggta agaatagccc ttcttacgaa tatcctctcc ttgaaaaagg atagaacctt
    28561 caacaggact atctagacca gcaagtaggg acaagagtgt ggattttcct gctcctgact
    28621 ccccaataat actgtaaaat tttccgggtt caaaattata attgatctga tataggactg
    28681 cttcagcagt attcttataa cggtaggtaa catcttgtaa ttgtaataaa gtcatgattt
    28741 ctccttctta actaatagat gataaaattt ctttcggtga ttttctaaat aagaatagga
    28801 aacaaagggc tacagataag caactaagca gaactagaaa aacataggat tctgcaaaag
    28861 ataagatgct agttgataaa ctgcttgctt tggctagtgt atcttgtaag cttacctgat
    28921 ctccacttgc tagtagagtt tggagtaggt aagttgtgat tccgtttcct gcaacaaatg
    28981 ctggaagcaa agctccaaga gataccaaaa ctacctctaa acagaattgt aggaagatcg
    29041 agctcttgcc ttttccaagt gcaagtaaaa tccccacttc atagacccgt tctctcaacc
    29101 agagagacaa aaccagaatt aaggctccag ctcctgctat caacatccca taaaggaaga
    29161 tggtcaggaa ggtttggaaa gttgcaactg agtctttgat ttgttcaaaa gccttgtttt
    29221 ccttttcgac ttggtagcct tgattttcca aggccaagtt ttctacctgc ttcatgagtc
    29281 cgtccatttc cttaggattt tctacataga agcgtgctgc actgacttga gcttcactat
    29341 tgcccaaaag ggtttggcta ctttcataat ctgtaaagac ttgattttca ctgaagtcag
    29401 aagacaagcc tgtgaatttc tcttgttttt taccagaaaa gatgccgata atctcaaact
    29461 ctactgtttg tccttttcca gattcagact gaccagcatc caagccaatc ttgtcatgaa
    29521 gtgaaagacc gttcttctta gccaattctt cgtggataag gattttcttg gaatcccctt
    29581 tttgaaggtg tcgcccttct tttagattga aagccgaact ggtaaaggtt acatccttgg
    29641 atgaatcctc aagagccgtt aagctaacca agttattgtc tgcagctgat aaatcatcac
    29701 gctccacgct ctgctcgcca gtcactgctt ccttgtcttt tagttttgcg accgtctcaa
    29761 gttcaggaga gacattttcc agccccttaa tcttgcttac agatgctagg tctgacaact
    29821 tgaatgtctg accattctct atcttcttaa tagaaaaaga tgtattgagt gatttataaa
    29881 gattgctttc tactgttttg ttggacttca tcagagtcaa acaggctgaa attccggcca
    29941 ataagaccaa taaaatcaga aataaaataa aacttctcag tcgctttctg ctgacataag
    30001 cccaagatct ttggattgga ttcatttgtc acctccatat ttgtaagact attataaaac
    30061 ccaaatatga aatgtttatg aaatacgaaa aaaaatatcg agtaggggat aatctctagc
    30121 ccctctcaca ccaccgt
//
LOCUS       DAVBOG010000027        26676 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.027, whole genome shotgun sequence.
ACCESSION   DAVBOG010000027 DAVBOG010000000
VERSION     DAVBOG010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26676
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.027"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..285)
                     /locus_tag="VQ865_001256"
                     /pseudo
     CDS             complement(1..285)
                     /locus_tag="VQ865_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            complement(347..796)
                     /locus_tag="VQ865_001257"
     CDS             complement(347..796)
                     /locus_tag="VQ865_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3135590.1"
                     /translation="MTLTTFLLQAVASFLAIITFLIVLNVQRSMLLPGGILGMTVWLI
                     YLLLKEPTNVIVATFIAAIIGSCVSQILSILYKTPAVVFILAILAPLVPGYLSYRTTA
                     FFVTGDYNKALASATLVVMLALVISIGMASGTVILRLYHYIKTHRVS"
     gene            complement(798..1556)
                     /locus_tag="VQ865_001258"
     CDS             complement(798..1556)
                     /locus_tag="VQ865_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HET3135591.1"
                     /translation="MEESKELNAVIDVIMLAGTILLKSGSEIHRVEDTMIRIAHSQGI
                     VDCNVLAMPAAIFFSIENTNISRMKRVTSSSYNIEKVCDVNQISRQLVGGQIDLETAF
                     KQLTALQAQPLPYTKLQVTLAATFSAPFFSVMFSGNIYDALGAGVATLFGFAFSLYVE
                     KFIRIPFVTAFAGAFVFGIIAQFWARYTGFPSTADLIIAGAVMPFVPGIALTNAVRDI
                     MTNHINSGMSKMFESLLITLALGAGTSVALVLVN"
     gene            complement(1671..3650)
                     /gene="pknB"
                     /locus_tag="VQ865_001259"
     CDS             complement(1671..3650)
                     /gene="pknB"
                     /locus_tag="VQ865_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HET3135592.1"
                     /translation="MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVL
                     RTNYQTDPIAVARFQREARAMADLDHPHIVRITDIGEEDGQQYLAMEYVAGLDLKRYI
                     KEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTAKVTDFGIAVA
                     FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAV
                     TIALQHFQKPLPSVIAENPSVPQALENVIIKATAKKLTNRYRSVSEMYVDLSSSLSYN
                     RRNESKLIFDETSKADTKTLPKVSQSTLTSIPKVQAQTEHKSIKNPSQAVTEETYQPQ
                     APKKHRFKMRYLILLASLVLVAASLIWILSRTPATIAIPDVAGQTVAEAKATLKKANF
                     EIGEEKTEASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSSD
                     VIAELKEKKVPDNLIKIEEEESNESEAGTVLKQSLPEGTTYDLSKATQIVLTVAKKAT
                     TIQLGNYIGRNSTEVISELKQKKVPENLIKIEEEESSESEPGTIMKQSPGAGTTYDVS
                     KPTQIVLTVAKKVTSVAMPSYIGSSLEFTKNNLIQIVGIKEANIEVVEVTTAPAGSAE
                     GMVVEQSPRAGEKVDLNKTRVKISIYKPKTTSATP"
     gene            complement(3647..4387)
                     /locus_tag="VQ865_001260"
     CDS             complement(3647..4387)
                     /locus_tag="VQ865_001260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HET3135593.1"
                     /translation="MEISLLTDVGQKRTNNQDYVNHYVNRAGRTMIILADGMGGHRAG
                     NIASEMAVTDLGVAWVDTQIDTVNEVREWFAHYLEIENQKIHQLGQDEAYRGMGTTLE
                     VLAIIDNQAIYAHIGDSRIGLIRGEEYHQLTSDHSLVNELLKAGQLTPEEAEAHPQKN
                     IITQSIGQKDEIQPDFGTVILESGDYLLLNSDGLTNMISGSEIRDIVTSDIPLADKTE
                     TLVRFANNAGGLDNITVALVSMNEEDAE"
     gene            complement(4402..5715)
                     /gene="rsmB"
                     /locus_tag="VQ865_001261"
     CDS             complement(4402..5715)
                     /gene="rsmB"
                     /locus_tag="VQ865_001261"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HET3135594.1"
                     /translation="MTKVETARSLALAVLEDVFVNQAYSNIALNKHLKGSQLSAADKG
                     LVTELVYGTVARKLTLEWYLSHFIEDRDQLDSWLYVLLLMSVYQLRYLDKIPDHAVVN
                     EAVELAKLRKKGSEKLVNAVLRRILREGWPDIANIKRKNKRDSIAYSLPVWLVTKLKE
                     EYGEERAKAIFESLLVRNKASIRVTDLSRKEEIQALLEANSSLLATTGLVKEQGHFAG
                     HNLFADGAITIQDESSQLVAPTLDLQGDERVLDACAAPGGKTAHIASYLTTGQVTALD
                     LYDHKLDLIQENAQRLGVEDRVQTQKLDARKVHEFFDQDSFDKILVDAPCSGIGLLRR
                     KPDIKYNKETADFASLQEIQLEILGSVCQILGKGGIITYSTCTIVSEENFQVVKAFLE
                     SHPEFEQVKLEHECKDIMKDGCILITPELYGSDGFFISQFRKISD"
     gene            complement(5708..6643)
                     /locus_tag="VQ865_001262"
     CDS             complement(5708..6643)
                     /locus_tag="VQ865_001262"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000163675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HET3135595.1"
                     /translation="MTKLIFMGTPDFSATVLKGLLTDDRYEILAVVTQPDRAVGRKKV
                     IQETPVKQAAKEAGLSIYQPEKLSGSPEMEELMKLGADGIVTAAFGQFLPSKLLDSMD
                     FAVNVHASLLPRHRGGAPIHYALIQGDEEAGVTIMEMVKEMDAGDMISRRSIPITDED
                     NVGTLFEKLALVGRDLLLDTLPAYIAGDIKPEPQDTSQVTFSPNIKPEEEKLDWNKTN
                     RQLFNQIRGMNPWPVAHTFLKGDRFKIYEALPVEGQGNPGEILSIGKKELIVATAEGA
                     LSLKQVQPAGKPKMDIASFLNGVGRTLTVGERFGD"
     gene            complement(6656..9052)
                     /locus_tag="VQ865_001263"
     CDS             complement(6656..9052)
                     /locus_tag="VQ865_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001162119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HET3135596.1"
                     /translation="MALAKIIVDVPLMQTDQPYSYRIPEEFEGMLEVGMRVHVPFGKG
                     NRLIQGIVLGLESQSDGEEMEQDLKDIAEVLDFSPVLTPEQLWLAEELRKSVFSYKIS
                     ILKTMLPGFLNSSYDKILYPLEGLSQEERVRLFGSEDSLAFSSLDLAKQAEMMRLTRK
                     GLLGLEYQAVDQKKVKTQSWYEVDHAQLEGVEISTRAKKKLELRDYLLSHPESASLAS
                     LLESYSREQVNFFVDQGAVTIVQKEVQRSAAYFEGIEASRPLELNPEQRQARDAVVSS
                     IGSSQPPFLLQGITGSGKTEVYLQIIQGALDKGKTAILLVPEISLTPQMTERFIARFG
                     DKVAILHSGLSNGEKYDEWRKVERGDAQVVVGARSAIFAPLKNLGVMIIDEEHEAAYK
                     QDSNPRYHAREVAILRAQYNQATLVLGSATPSLESRARAGKGVYQHLRLTQRANPLAT
                     IPEVQVIDFRDYIGQNETSNFTPPLLEAIQDRLVKKEQVVLMLNRRGYSSFVMCRECG
                     TVDTCPNCDISLTLHMDTKTMNCHYCGFSKDIPQVCPNCKSHSIRYYGTGTQKAYDEL
                     AELFPQARIFRMDVDTTRKKGSHQALLDQFGRGEADILLGTQMIAKGLDFPNVTLVGV
                     LNADTALNLPDFRSSERTFQLLTQVAGRAGRAEKAGQVLIQSYNSQHYAIRFAKDQDY
                     EGFYAYEMGIRRQLGYPPYYFTIGITLSHKKEEEVFKRAYEVMNILRSGLSETSPILG
                     PTPKPIARTHNLYHYQILIKYRLEDELGPTLNQVLALTQERENSELRLSIDHEPQQFL
                     "
     gene            complement(9118..9432)
                     /locus_tag="VQ865_001264"
     CDS             complement(9118..9432)
                     /locus_tag="VQ865_001264"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001817694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HET3135597.1"
                     /translation="MMLKPSIDTLLDKVPSKYSLVILEAKRAHELEAGAPATQGFKSE
                     KSTLRALEEIESGNVTIHPDPEGKREAVRRRIEEEKRRKEEEEKKIKEQIAKEKEDGE
                     KI"
     gene            complement(9457..10083)
                     /gene="gmk"
                     /locus_tag="VQ865_001265"
     CDS             complement(9457..10083)
                     /gene="gmk"
                     /locus_tag="VQ865_001265"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000775037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HET3135598.1"
                     /translation="MADRGLLIVFSGPSGVGKGTVRREIFESSENQFQYSVSMTTRAQ
                     RPGEVDGVDYFFRTREEFEELIRQGQMLEYAEYVGNYYGTPLTYVNETLDKGIDVFLE
                     IEVQGALQVKKKVPDAVFIFLTPPDLDELQDRLVGRGTDSAEVIAQRIEKAKEEIALM
                     REYDYAIVNDQVPLAAERVKCVIEAEHFCVDRVIGHYQEMLPKSPTTR"
     gene            complement(10213..11826)
                     /locus_tag="VQ865_001266"
     CDS             complement(10213..11826)
                     /locus_tag="VQ865_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007520539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HET3135599.1"
                     /translation="MEIMSLAIAVFAVIIGLVIGYVSISAKMKSSQEAAELMLLNAEQ
                     EATNLRGQAEREADLLVNEAKRESKSLKKEALLEAKEEARKYREEVDAEFKSERQELK
                     QIESRLTERATSLDRKDDNLTSKEQTLEQKEQSISDRAKNLDAREEQLEEVERQKEAE
                     LERIGALSQAEARDIILAQTEENLTREIASRIREAEQEVKERSDKMAKDILVQAMQRI
                     AGEYVAESTNSTVHLPDDTMKGRIIGREGRNIRTFESLTGVDVIIDDTPEVVTLSGFD
                     PIRREIARMTMEMLLKDGRIHPARIEELVEKNRQEIDNKIREYGEAAAYEIGAPNLHP
                     DLMKIMGRLQFRTSYGQNVLRHSIEVAKLAGIMASELGENAALARRAGFLHDIGKAID
                     HEVEGSHVEIGMELARKYKEPPVVVNTIASHHGDVEAESVIAVIVAAADALSAARPGA
                     RSESLESYIKRLHDLEEIANGFEGVQTSFALQAGREIRIMVNPGKIKDDKVTILAHKV
                     RKKIENNLDYPGNIKVTVIRELRAVDYAK"
     gene            complement(12169..14916)
                     /locus_tag="VQ865_001267"
     CDS             complement(12169..14916)
                     /locus_tag="VQ865_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIR2 family protein"
                     /protein_id="HET3135600.1"
                     /translation="MEENYNLSITQIKNSIKENSLVLFVGAGISANSNLPTWGELIQS
                     LKKELNIPEERTDSPLRIAQYYYDTFGKNQYTKKIEEIFFKKGLSKPNELHKLIEKIA
                     PKHIITTNYDSLLESQFESGLLKYNVVAEDKDIPYTSSERYLIKMHGDFSKKNIVLKE
                     DDYLDYHLNFPMISTLIQSLIMNHTLLFVGYSLSDSTFNSIFRMIQNTFKLDAKNAYF
                     YTPEEPSMIIREYYKKQGIFIISNEENLGQETSEKQNKLYCRTKDFLEVLSENRSQDV
                     NNADDLWNQLAFLDRLSFIDAKDFSRYSDLKKRALNWDDEYCWFGNDQLRFEIDGHEE
                     LRIMVSKKSLLNRFLDMEIGEPRDLKGNRFLSKAFKLYEEKQYSLAKAKFRELANIAF
                     RQKDYFNFLVCEFNFQQIQIIDRYEKTPSYAEPLYDGELSELTEQILNSVTGDEKKII
                     EFFRDSILNFNFLYRKLETINELFDEIREEHESYRRGGWSANNHLFNAEFTVKNLYNF
                     LKLNCLCVEHYKIYKSIINRYLEILLLSYDNSYVNPDSSIFDRTSSWLKNLDLDDVKL
                     ILPNIDFKVVNLYFRNYSFGKIKVTEEAKDYLLNRITYLQERLEITEDENLRELKNML
                     IFLPLVDDIDIEKVIEILNNQTLYYNWSEEFRRIIKIVLDNMDVIDKDSLKSKIIGIV
                     NKHLNEILEKNFSLYNSVYPLYSQLLEYCSTDQETAIIVLEKFNTDILRIKYKNDDIK
                     NIIEYSDLICHLFKYFEKDIKDDILDTLKVYEESENIIYHKVIDLMSYNVYDFPQIQN
                     KIYHYLIKRINDKRVEGVKTFPDPREKSVSDLYNLSRKGYFSDFEILKDIEEDIRGLY
                     PEVDWTWFHDRSDDVIHRLLEHRTPNNIKTYFSKNEEDNKLINEYILKAFDEDKLILK
                     K"
     gene            complement(15263..16360)
                     /locus_tag="VQ865_001268"
     CDS             complement(15263..16360)
                     /locus_tag="VQ865_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000156376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HET3135601.1"
                     /translation="MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAI
                     VDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLD
                     YQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYA
                     KAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQA
                     SKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRY
                     TKARVRRLLTYILVQARENVLPEAIHVLGFTEKGRQHLKSLKGQVNLVSRIGKEPWDA
                     MTQKVDQIYQLGKPSIAEQNFGRVPIRIETN"
     gene            complement(16370..17116)
                     /locus_tag="VQ865_001269"
     CDS             complement(16370..17116)
                     /locus_tag="VQ865_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3135602.1"
                     /translation="MIMATYETFAAVYDAVMDDSLYDKWTNFSLRHLPKTKERKKLLE
                     LACGTGIQSVRFSQAGFDVTGLDLSADMLKIAEKRATSAKQKIAFIEGNMLNLSKAGK
                     YDFVTCYSDSICYMQDEVEVGDVFKDVYNALNEEGVFIFDVHSTYQTDEVFPGYSYHE
                     NAEDFAMLWDTYEDEVPHSIVHELTFFIKEADGSFSRHDEVHEERTYEILTYEILLEQ
                     AGFKSFKLYADFEDKEPTETSTRWFFVAQK"
     gene            complement(17219..17572)
                     /gene="rsfS"
                     /locus_tag="VQ865_001270"
     CDS             complement(17219..17572)
                     /gene="rsfS"
                     /locus_tag="VQ865_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HET3135603.1"
                     /translation="MNEKELLELVVKAADEKRAEDILALDVQDLTSVTDYFVITSSMN
                     SRQLDAIAANIREKVAQAGFKGSHIEGDAAGGWVLLDLGAVVVHIFSEEMRAHYNLEK
                     LWHEANSVDISEALA"
     gene            complement(17585..18085)
                     /locus_tag="VQ865_001271"
     CDS             complement(17585..18085)
                     /locus_tag="VQ865_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000844697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HET3135604.1"
                     /translation="MKTAFIIIDVQNVLVETGFQTKSLLEKISYLQNQARSKNIEIIY
                     VQHIENSEAQTSEDWQLSALLNRKPAEKVFQKKYNSIFKETGLKEYLDKQGIEKLVLC
                     GMQTEYCVDTSVKVAFEYGYQLIVPEGAVTTFDGDDIPAETINEFYEDIWEECFADVL
                     DYKHIF"
     gene            complement(18086..18679)
                     /gene="yqeK"
                     /locus_tag="VQ865_001272"
     CDS             complement(18086..18679)
                     /gene="yqeK"
                     /locus_tag="VQ865_001272"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HET3135605.1"
                     /translation="MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRF
                     GVDVEKASLAGLLHDYAKKLSDQEFLDLIDRYQLDFDLKNWGNNVWHGMVGIYKIQED
                     LDLHDSEILRAIEVHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKA
                     VAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED"
     gene            complement(18679..19308)
                     /locus_tag="VQ865_001273"
     CDS             complement(18679..19308)
                     /locus_tag="VQ865_001273"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HET3135606.1"
                     /translation="MTIELLTPFTKVELEPEIKEKKRKQVGILGGNFNPVHNAHLIVA
                     DQVRQQLGLDQVLLMPEYQPPHVDKKETIPEHHRLKMLELAIEGIDGLVIETIELERK
                     GISYTYDTMKILTEQHPDTDYYFIIGADMVDYLPKWYRIDELVDMVQFVGVQRPRYKA
                     GTSYPVIWVDVPLMDISSSMVRDFIAQGRKPNFLLPQPVLDYIEKEGLY"
     gene            complement(19360..19671)
                     /gene="yhbY"
                     /locus_tag="VQ865_001274"
     CDS             complement(19360..19671)
                     /gene="yhbY"
                     /locus_tag="VQ865_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HET3135607.1"
                     /translation="MSLTSKQRAFLNSQAHTLKPIIQIGKNGLNDQIKTSVRQALDAR
                     ELIKVTLLQNTDENIHEVAEILEEEIGVDTVQKIGRILILFKQSSKKENRKISKKVKE
                     I"
     gene            complement(19885..20991)
                     /gene="yqeH"
                     /locus_tag="VQ865_001275"
     CDS             complement(19885..20991)
                     /gene="yqeH"
                     /locus_tag="VQ865_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000391231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HET3135608.1"
                     /translation="MEEILCIGCGATIQTTDKAGLGFTPQSALEKGLETGEVYCQRCF
                     RLRHYNEITDVQLTNDDFLKLLHEVGDSDALVVNVIDIFDFNGSVIPGLPRFVSGNDV
                     LLVGNKKDILPKSVKSGKISQWLMKRAHEEGLRPVDVVLTSAQNKHAIKEVIDKIEHY
                     RKGRDVYVVGVTNVGKSTLINAIIQEITGDQNVITTSRFPGTTLDKIEIPLDDGSYIY
                     DTPGIIHRHQMAHYLTAKNLKYVSPKKEIKPKTYQLNPEQTLFLGGLGRFDFIAGEKQ
                     GFTAFFDNELKLHRSKFEGASAFYDKHLGTLLTPPNSKEKEDFPRLVQHVFTIKDKTD
                     LVISGLGWIRVTGIAKVAVWAPEGVAVVTRKAII"
     gene            complement(20994..21584)
                     /locus_tag="VQ865_001276"
     CDS             complement(20994..21584)
                     /locus_tag="VQ865_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HET3135609.1"
                     /translation="MDCFILVTKENCEKKLRKGARMAIENYIPDFAVEAVYDLTVPSL
                     QAQGIKAVLVDLDNTLIAWNNPDGTPEMKQWLHDLRDAGIGIIVVSNNTKKRVQRAVE
                     KFGIDYVYWALKPFTFGIDRAMKEFHYDKKEVVMVGDQLMTDIRAAHRAGIRSILVKP
                     LVQHDSIKTQINRTRERRVMRKITEKYGPITYKKGI"
     gene            complement(21536..22444)
                     /locus_tag="VQ865_001277"
     CDS             complement(21536..22444)
                     /locus_tag="VQ865_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HET3135610.1"
                     /translation="MVLEKQLGNGCTWIDLDLGKLNKLEDLSEIYGLDKETIEYALDR
                     NERAHMDYHRESGTVTFIYNVLDVKKDKAYYETFPMTFIVEHRRLITISNTKNAYVIE
                     QMTRYLESHDTLSIYKFLFASLEIISNAYYPVIEQMDKSRDEVNDLLRQRTTKKNLFA
                     LSDLETGMVYLTAAAKQNRILLEHIQGHALYRSFDEIEREQFDDAMIEAHQLVSMTDL
                     ISQILQQLSASYNNILNNNLNDNLTTLTIISVLLAVLAVVTGFFGMNVPLPLTDEPHA
                     WLYISLASAGLWIVLSLLLRKIAKKS"
     gene            complement(22501..23061)
                     /locus_tag="VQ865_001278"
     CDS             complement(22501..23061)
                     /locus_tag="VQ865_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel"
                     /protein_id="HET3135611.1"
                     /translation="MQKFIQAYIEKLDVTTIIENILTKVISLLLLLIVFYIAKKMLHT
                     MVQRIVKPSLKMSRHDVGRQKTISRLLENVFNYTLYFFLLYCILSILGLPVSSLLAGA
                     GIAGVAIGMGAQGFLSDVINGFFILFERQLDVGDEVVLTNGPITVSGKVVSVGIRTTQ
                     LRSEEQALHFVPNRNITVVSNFSRTD"
     gene            23200..24408
                     /gene="sstT"
                     /locus_tag="VQ865_001279"
                     /pseudo
     CDS             23200..24408
                     /gene="sstT"
                     /locus_tag="VQ865_001279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000713440.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
     gene            24476..25429
                     /locus_tag="VQ865_001280"
     CDS             24476..25429
                     /locus_tag="VQ865_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000028179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3135612.1"
                     /translation="MSISQRTTKLILATCLACLLAYFLNLSSAVSAGIIALLSLSDTR
                     RSTLKLARNRLFSMLLALAIGVLAFHLSGFHIWSLGLYLAFYVPLAYKMGWEIGITPS
                     TVLVSHLLVQESTSPDLLVNEFLLFAIGTGFALLVNLYMPSREEEIQHYHTLVEEKLK
                     DILQRFKYYLSRGDGRNRAQLVAELDTLLKEALRLVYLDHSDHLFHQTDYHIHYFEMR
                     QRQSRILRNMAQQINTCHLAASESLILAQLFSKIAGQLSQTNPASDLLDEIERYLEVF
                     RNRSLPKTREEFETRATLLQLLREAKTFIQVKVDFYQKYRQ"
     gene            25572..25952
                     /locus_tag="VQ865_001281"
     CDS             25572..25952
                     /locus_tag="VQ865_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HET3135613.1"
                     /translation="MTYLEKWFDFNRRQKEIESLLEETIAQQSEQSLTLKEFYLLYYL
                     DLAEEKSLRQIDLPDKLHLSPSAVSRMVARLEAKNCGLLSRMCCHQDRRSSFICLTND
                     GQKTLASLQKTVEESLEAGLDFLI"
     gene            26051..26272
                     /locus_tag="VQ865_001282"
     CDS             26051..26272
                     /locus_tag="VQ865_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3135614.1"
                     /translation="MIEITYIDASKNERTVTFESYEDFERSQQACLIGVADYYPVQKL
                     TYKGHNLDYHGTYGDIFFYLMKQDLSQYN"
     gene            26289..26603
                     /gene="trxA"
                     /locus_tag="VQ865_001283"
     CDS             26289..26603
                     /gene="trxA"
                     /locus_tag="VQ865_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003004519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3135615.1"
                     /translation="MAKAITDATFEQETKDGLVLVDFWATWCGPCRMQGPILDKLSEE
                     LSEDVLKIVKMDVDENPNTARAFGIMSIPTLLFKKDGQVVKQVAGVHTAEQIKAIIAE
                     LS"
BASE COUNT         7448 a         6013 c         4984 g         8231 t
ORIGIN      
        1 tccaaagaaa caattctccc ttgacttgtg acaatcgctt gagccttcat agcgtggcat
       61 ttctttttac cagaataatt cgctaattct ttttttaggg cgattgattt ttacttccgt
      121 cgcatcaatc attaccgtgt cctcagaact gagaggagtt cttgaaatcg taaaaccact
      181 ttgaacaaga gttacttcaa cccattggct ccgacggagt aagttgcttt cgtggatacc
      241 aaaatcagcc gcaatttctt cataagttcg atattctcgc acatatagaa agcgttgtta
      301 atttatttat ctcatttttc agaaaattct tttatttctg taaaatctac gatactcgat
      361 gtgtttttat ataatgatac agtctgagaa tcactgttcc gctagccatt ccaatagaga
      421 ttaccaaagc caacatgaca accaaggtcg cacttgccag tgctttatta tagtcccctg
      481 tcacaaaaaa ggcagttgtt cggtaggaga gataacctgg aaccagcggt gccaaaatgg
      541 ccaagataaa gaccacagca ggtgtcttat aaagaatact taaaatctgg ctgacacaag
      601 aaccaataat ggctgcaatg aaggtagcta caatgacatt ggtcggttcc ttgagcaaga
      661 gatagattag ccagacagtc atgcccaaaa tccctccagg taagagcata gaccgttgca
      721 cattgagtac gattaaaaaa gtgataatgg caagaaaact tgctactgct tgtaataaaa
      781 aggttgttag tgtcatatta gttcaccaat accaaggcga cagaagttcc tgcccctaaa
      841 gcgagggtaa tgagcaggga ttcaaacatc ttactcatac cagagtttat gtggttggtc
      901 ataatatcac ggaccgcatt ggtcaaggca atacctggta caaacggcat gaccgcacca
      961 gctataatca aatctgccgt tgaaggaaaa cctgtgtagc gagcccaaaa ctgggcaatt
     1021 atcccaaaga caaaggctcc agcaaaggct gtcacaaagg gaattcggat aaatttttcc
     1081 acatagaggg aaaaggcaaa accaaataag gtcgccactc ctgccccaag tgcgtcgtag
     1141 atatttccgc taaacataac tgaaaagaaa ggagcactaa aggtcgcagc cagagttacc
     1201 tgcaacttag tatagggaag gggttgagct tgcaaggccg tcaattgctt aaaggctgtt
     1261 tctaaatcaa tctgcccccc aaccagctga cgagaaatct ggttcacatc gcagactttt
     1321 tcgatgttat aagaagagga ggtcacgcgc ttcatgcgcg aaatattggt attttcaata
     1381 gagaaaaaga tagcggcagg catggcaagg acattgcaat ccacaatccc ctgcgaatgc
     1441 gcgattcgaa tcatggtatc ttctacacga tggatttctg agccactttt aaggagaata
     1501 gtccccgcta gcataatcac atcaatgacg gcatttaatt cttttgattc ttccatgctt
     1561 tcctcctttt atcaactccc tctattctat cacaaatctg gactcaaaaa aaatctttgc
     1621 catgaaatca tgacaaagat tgattactca ttttgattat ccatctactt ttaaggagta
     1681 gctgaagttg ttttaggttt gtagattgaa atcttgactc tagtcttatt gaggtctacc
     1741 ttttcacctg ctctaggact ttgttcaaca accatgcctt ctgcactacc tgcaggcgct
     1801 gtcgtcactt ctacaacttc tatattagct tccttaatcc caacaatttg aatcaaattg
     1861 ttcttagtaa actccaagct ggaaccaatg taactcggca tggcaacact tgtaactttt
     1921 ttagctactg tcaagacaat ttgagtaggt ttactcacat cataagtcgt tccggcacct
     1981 ggactttgtt tcataatcgt tcctggttcg ctttcgctgg actcttcttc ctctatctta
     2041 atcaaattct caggaacctt cttctgcttg agttctgaga ttacttctgt agagttccgt
     2101 ccaatatagt tccctaattg aatcgtcgta gcttttttag ctactgtcaa aacaatttga
     2161 gttgccttgc tcaagtcata ggtcgtacct tctggtagac tttgcttcag gaccgttcca
     2221 gcctcactct cattcgactc ttcttcctca attttaatca aattatctgg aacttttttc
     2281 tcttttaatt ccgcgataac atcagaagat ttccggccga cataattact aatttggaag
     2341 gattgtttgc ctgatgagac aaccagattg attttcgttc cttcttttcg accagttcca
     2401 gcgccaggat ctgtacggat aatccgccct tcttccacct tttcactagc ctctgtcttc
     2461 tcctcaccaa tctcaaaatt ggcttttttg agcgttgcct tggcctctgc aactgtctga
     2521 cctgccacat ctggaatggc aatggttgca ggagttctgg atagtatcca aataagagaa
     2581 gctgccacca atacaaggct ggccaacaaa atcaggtaac gcatcttaaa tctatgtttt
     2641 ttcggtgctt gtggttggta agtttcctct gtcacagcct ggcttgggtt tttgattgat
     2701 ttgtgttctg tctgcgcttg aaccttagga atagatgtca aggtactctg agaaaccttc
     2761 ggcaaggtct tggtatctgc cttgctcgtt tcatcaaaga ttaacttact ttcatttcta
     2821 cgattgtagg acaagctact agacaagtcc acatacatct ctgaaaccga gcggtagcga
     2881 ttggtcaact ttttagcagt tgccttgata ataacatttt ctaaagcctg aggtacagat
     2941 ggattttctg caataacgga cggcaggggt ttctggaaat gctggagggc aatggtcacc
     3001 gcgctatccc cgtcataagg gatatggcct gtcaacatct catagaaaat aatccccatg
     3061 gcatagatat cactctgcac agtcgccttc gaaccacgcg cctgctctgg tgacaagtaa
     3121 tgaactgagc ccaacatcga gttagtctgg gtcagacttg tctctgcaaa ggctacagca
     3181 atcccaaagt ctgtgacctt ggccgtccca tctggtgtca aaaggatatt ttgaggtttc
     3241 aagtccctgt gaacaattcc tcgagtatgg gccaagcgca tagccaagag aatttgtccc
     3301 atgatacgga ctgcttcttc attagaaaga ggataatgtt ccttgatata gcgtttgagg
     3361 tctagtccag caacatactc cattgcaaga tactgttgac cgtcttcctc accaatatct
     3421 gttatccgaa cgatatgagg atggtctaga tctgccatag ctctcgcttc acgctgaaaa
     3481 cgagctacag ctatcgggtc cgtctggtag ttggtcctca gaaccttcac tgccacttct
     3541 tccccatcta agattaagtc tttggctagg tagacatccg ccatacctcc tcgaccaatc
     3601 tgtttgacaa tccgatagcg tccggcaaaa atcttgccga tttggatcat tctgcatcct
     3661 cctcgttcat agaaacaagg gcaaccgtaa tgttgtctaa acctcctgca ttgttagcaa
     3721 aacgaacaag tgtctccgtt ttatctgcta aaggaatatc actggttaca atatcacgaa
     3781 tctcactgcc tgaaatcatg ttggtcaagc cgtcactatt gagcaagaga tagtcacctg
     3841 actcaaggat aactgtccca aaatcaggct gaatttcatc tttttgccca atagactggg
     3901 tgataatatt tttttgcgga tgagcttctg cctcttctgg tgtcaattga ccagccttga
     3961 gcaattcatt aaccaaggaa tgatcgctcg tcaactgatg gtattcttct ccacgaatca
     4021 agccgatacg cgaatcacca atatgagcat agatagcctg attatcaata atagcaagga
     4081 cttccaaagt agttcccatg cctctgtaag cttcatcctg accaagctgg tgaatctttt
     4141 gattttcaat ttctaggtaa tgggcgaacc attcacgcac ttcattgact gtatcgatct
     4201 gggtatcaac ccaagctaca cccaggtctg tgaccgccat ttcactagcg atattccctg
     4261 cacgatgacc tcccatccca tcagctaaaa taatcatggt acgtccagct ctattgacat
     4321 agtggttgac atagtcttgg ttatttgttc gtttctgacc aacatctgtt aataatgaaa
     4381 tttccatgtg tcagttcctt cctaatccga tatcttgcga aattgactga tgaagaatcc
     4441 atcacttcca tacaattcag gtgtaatgag gatacagccg tctttcatga tatccttaca
     4501 ttcatgttct agttttacct gctcgaactc gggatgactc tctaaaaagg ccttaacgac
     4561 ttgaaaattc tcctctgaga cgatagtgca ggtgctataa gttattatac cacctttgcc
     4621 tagtatttga caaacactac ctaatatttc taactgaatt tcctgcaagg acgcgaaatc
     4681 tgccgtttct ttattgtatt tgatatctgg ttttcggcgc aaaagaccga ttcctgaaca
     4741 aggagcatcc accaaaatct tatcaaagga atcctggtca aaaaactcat gcacctttct
     4801 ggcatccaat ttttgagttt gaacccgatc ttcaactccc agacgttggg cattttcttg
     4861 aattaaatcc aacttgtggt cgtacaagtc cagagcagta acctgacctg tcgtaagata
     4921 agaggctata tgggctgttt tcccacctgg agccgcacag gcatcaagca ctcgctcatc
     4981 accttgtaaa tcaagcgtcg gagcaaccag ctgactggac tcatcttgga tggtaatggc
     5041 tccatccgca aacaaattat gccctgcaaa atgcccttgc tccttaacca gaccagtggt
     5101 tgctaaaagg gaactattcg cctccaacaa ggcttggatt tcctcttttc gacttaggtc
     5161 tgttacacga atactagctt tgtttcgcac taacaagctt tcaaagatgg cttttgctct
     5221 ctcctctccg tattcttcct tgagtttggt aactagccaa actgggagag aataggcaat
     5281 ggagtcacgc ttgttttttc gcttgatgtt agcaatatct ggccagcctt cacgcaagat
     5341 acggcgaagg acagcgttga ccaatttttc actgcctttt ttacggagtt tggccaattc
     5401 cactgcttca ttgaccacag catgatctgg aatcttgtcc aaatagcgga gttggtagac
     5461 actcatgaga agaaggacat agagccagct gtctaactgg tctctgtctt cgataaagtg
     5521 ggataggtac cattccagag tcagtttacg ggctaccgtt ccatagacta gctcggtcac
     5581 taagcccttg tctgctgcag agagctgact ccccttgagg tgtttattta aggcgatatt
     5641 tgaatatgct tggttcacaa aaacatcctc tagcactgct agagctaaac ttctagccgt
     5701 ttctacttta gtcaccaaat cgttctccta cagtcaatgt acgtccaact ccgttgagga
     5761 aggaagcaat gtccatctta ggcttaccag ctggctgcac ttgtttgagg gatagagccc
     5821 cttcagccgt tgcgacaatc aattctttct tgccgataga gagaatctca cctggatttc
     5881 cctgaccttc tactggtagg gcttcataaa tcttaaagcg gtcgccctta aggaaagtat
     5941 gggcaacagg ccaggggttc attccacgaa tttggttaaa gagttgacga ttggttttgt
     6001 tccagtccag tttttcttcc tctggcttta tatttggaga gaaggtaacc tgactcgtat
     6061 cctgcggttc aggtttgata tcaccagcaa tataggcagg cagagtgtcc aaaagcaaat
     6121 cacgaccaac tagcgccaat ttttcaaaca aggtgccaac attgtcctca tctgtgatcg
     6181 gaatgctgcg acgagaaatc atatctcctg catccatttc cttaaccatt tccatgatgg
     6241 tcacaccagc ttcctcatcc ccttgaatca aggcataatg gataggcgca ccaccacggt
     6301 gtctaggaag gagggaggca tgaacgttga cagcaaagtc catgctatca aggagtttgc
     6361 ttgggagaaa ctgcccaaaa gcagcagtca caattccatc tgctcctagc ttcataagtt
     6421 cttccatctc tggacttcca gataattttt caggttggta gatagatagt cctgcttcct
     6481 tggcagcctg cttgactggg gtttcttgga taactttttt acgaccaaca gcacggtctg
     6541 gctgggtcac aacggctaga atttcgtaac ggtcatctgt caaaagtcct tttaagactg
     6601 ttgctgaaaa gtcgggggtc cccataaaga ttagttttgt catatcttct ccttcttata
     6661 aaaattgctg cggctcatgg tcaatgctga gacggagctc actattttcc cgttcttgag
     6721 tcaaggccaa gacctggttg agggtcggcc ccagctcatc ttctaaacgg tatttaatta
     6781 aaatctggta atgatagagg ttgtgggtac gggcaatcgg ttttggcgtt ggccccagaa
     6841 tgggactggt ctctgacaag cctgaccgca aaatgttcat gacttcatag gcacgtttga
     6901 aaacctcttc ttctttcttg tgagaaaggg taataccaat cgtgaaatag taaggtggat
     6961 agccgagttg tcgtctgatt cccatttcat aggcataaaa gccttcgtaa tcttgatcct
     7021 tggcaaatcg aatagcatag tgctgcgaat tgtaggactg tatcaagact tgacctgctt
     7081 tttcagcccg acctgctcga cctgctacct gagtcaagag ctggaaggtt ctctcagaag
     7141 aacggaaatc aggcagattc aaggccgtat ccgcatttag aactccgact agggtaacat
     7201 tgggaaaatc caaacccttt gcaatcatct gagtaccaag taaaatatcc gcttcccctc
     7261 gcccaaactg gtcaagcaag gcttggtgac tgcctttctt tcgagtcgta tccacatcca
     7321 tcctaaaaat gcgagcttgg ggaaagagtt ctgctagctc atcataagcc ttctgagttc
     7381 ccgtcccata gtaacgaata ctgtggctct tacagttagg acagacctga ggaatatcct
     7441 tcgagaaacc acaataatgg cagttcatag tcttggtatc catatgcaag gtcagagaaa
     7501 tatcgcagtt gggacaagta tccaccgtcc cacactcccg acacatgaca aagctagaat
     7561 aaccacggcg attgagcatg agaaccacct gctctttttt aaccagacgg tcttggatag
     7621 cctctagcaa aggaggcgta aagtttgacg tctcattttg tccgatatag tctcgaaagt
     7681 caatcacttg aacctcaggg attgtagcca aaggattggc acgttgggtt agacgtaagt
     7741 gttgatagac gcctttgcca gcacgtgccc ggctctctaa gctcggcgtt gcagatccaa
     7801 gtaccagagt tgcttgatta tactgagccc gtaaaatagc tacctctctg gcatggtaac
     7861 ggggattgct gtcctgctta taagccgctt catgctcttc atcaataatc atgacaccca
     7921 gatttttcag aggagcaaag atagcagatc tggcaccaac aacaacttgg gcatcgccac
     7981 gctccacctt gcgccattca tcatactttt caccattgga taatcctgag tgaagaatgg
     8041 ctaccttgtc cccaaaacgt gctataaaac gctcggtcat ctgaggagtc aaggaaatct
     8101 caggtaccag caaaatagct gtcttgccct tatccagggc accttggata atctgcaagt
     8161 aaacctcggt cttcccactt cctgtaatcc cttgaagtag aaagggaggt tgagaactgc
     8221 caatagaact cacaaccgca tcacgcgcct gtctttgttc tggatttaac tccaaaggtc
     8281 tacttgcttc aattccttca aaataagcag ccgagcgttg aacttccttt tggactatgg
     8341 taacagcacc ttgatccaca aagaagttga cttgctctcg cgagtaggac tctaacaagc
     8401 tagccaagga agcgctctct ggatgagaca gcagataatc tctcagttcc aactttttct
     8461 tggcacgtgt agaaatctca acaccttcta attgggcatg gtcaacctca taccaagact
     8521 gggtcttgac cttcttttga tcgactgcct gatattccag accaagcagg ccttttctag
     8581 tcaaacgcat catttcagct tgcttggcaa ggtctagtga agaaaaggct agcgaatctt
     8641 ctgaaccaaa caggcgtact cgttcttcct gactcaagcc ttccagagga tagagaatct
     8701 tgtcatagct agaattcaga aatcctggaa gcatggtctt gaggatagag attttgtagg
     8761 agaagacaga tttgcgtaac tcctcagcca gccagagttg ttctggcgtg agaacaggag
     8821 aaaaatccag cacctctgca atatctttta aatcttgctc catctcttct ccatctgatt
     8881 gggactccaa accaagaaca atcccttgaa tcaggcgatt acccttacca aaaggtacat
     8941 gaacccgcat cccaacttcc agcattccct caaattcctc cggaatcctg taactatagg
     9001 gctggtccgt ctgcatcaaa ggcacatcta cgataatctt agctagggcc atcttctcac
     9061 ctcctccttg tcagtacatt cttgcaatag aaaaaataag attgagtccc cccaacctta
     9121 aattttttca ccatcttctt tttctttagc aatttgctct ttgattttct tttcttcttc
     9181 ttctttgcgg cgtttctctt cttcgatacg gcgacgcact gcttcacgtt ttccttctgg
     9241 atctgggtga attgtaacgt ttcctgattc gatttcttct aaagcgcgaa gagttgattt
     9301 ttcagacttg aaaccttgag ttgctggggc acctgcttcc aattcgtggg cacgttttgc
     9361 ttccaagatt acgagtgaat attttgaagg aaccttgtcg agcaaggtat caatagaggg
     9421 ttttaacatc atttgcttgt acctattttc taaattttat cgggtagttg gagattttgg
     9481 taacatctcc tgatagtgac caatgacacg atccacacag aagtgttctg cttcaatcac
     9541 acatttgaca cgttcagcag ctaggggcac ctgatcgttg acaatcgcat aatcatactc
     9601 acgcatgagg gcaatttctt ccttggcctt ttcgattcgt tgggcaatca cttctgcact
     9661 atctgttcca cgacctacca agcgatcttg caattcatcc aaatctggtg gtgtcaggaa
     9721 gataaagaca gcatctggaa cctttttctt gacctgaaga gcaccctgaa cttcaatttc
     9781 aaggaaaaca tcgattccct tgtccaaggt ttcattgaca taggtcagag gagttccata
     9841 gtagttgccg acatattctg cgtattccaa catctgtcct tgacgaatca gctcttcaaa
     9901 ttcttcacga gtacggaaga aatagtcaac accgtccact tctccaggac gttgtgcgcg
     9961 tgtcgtcatc gatacagaat attgaaattg gttttcagaa ctctcaaaaa tctctcttct
    10021 aaccgttcct tttccaaccc ctgaaggacc agaaaaaacg attagtaagc ctcggtctgc
    10081 cattgtgtct ccttttagtc aatctgtgaa ataacatttc tctagaataa tggcaaaaag
    10141 ccagattatc ctttacagtc tttctatcta gtgtaacaaa aaagcagtaa tttttcaact
    10201 gctctttctt atttatttag cataatctac tgcacgaagc tcgcgaatca cggttacctt
    10261 gatatttcct ggataatcga gattgttttc aattttctta cgaactttgt gagccaagat
    10321 tgtgactttg tcgtccttga tttttcctgg attgaccatg atacgaattt cacgtcctgc
    10381 ttgaagggca aagctagttt gcactccttc aaagccgtta gcaatttctt ccaaatcatg
    10441 gagacgcttg atgtagcttt caagagactc actacgagca cctggacggg ctgcgctcaa
    10501 ggcatctgct gcagcgacga taactgctat cacgctctca gcttcaacat ctccgtggtg
    10561 actagcaatc gtattcacca caactggggg ttccttgtac ttacgggcca attccatacc
    10621 gatttcaacg tggctacctt caacctcatg gtcaatggct ttcccgatat cgtgaaggaa
    10681 tccagcacga cgggcaagag ccgcattttc accaagttcg ctcgccatga taccagccaa
    10741 cttagcaacc tcaatcgaat ggcgcaaaac attttgtcca tatgaagtac ggaactgcaa
    10801 acgtcccata atcttcatca agtctggatg aaggtttggc gcaccaattt cataggcagc
    10861 agcctcaccg tattcacgaa tcttattgtc aatctcttga cggtttttct caaccaactc
    10921 ttcgatacga gctggatgta tacgaccatc tttgagcaac atttccatag tcatacgggc
    10981 aatctcacga cgaatcggat caaatcctga caaggtcacc acttctggtg tatcgtcgat
    11041 aatcacatcg acccctgtca aactttcaaa ggtacgaatg ttacgacctt cacgaccaat
    11101 aatgcgtccc ttcatagtat cgtctggcag atgaactgtt gagtttgttg actccgctac
    11161 atattcacca gcgatacgtt gcatagcttg aaccaagata tccttggcca ttttgtcaga
    11221 acgttccttg acctcttgct cagcttcgcg aatgcgactg gcaatctccc tggtcaagtt
    11281 ttcctctgtc tgagccaaga taatatctcg tgcttctgcc tgagacagag caccaatacg
    11341 ctctagttct gcttcttttt gtctttcgac ttcctctaat tgctcttcac gcgcatcaag
    11401 gtttttcgct ctatcagaaa tactttgttc tttttgttca agtgtttgtt ctttactcgt
    11461 caaattgtcg tccttacggt caaggctagt agctctctct gtcaaacgac tttcgatttg
    11521 tttgagttct tgacgttctg atttgaattc agcgtccact tcttcacggt attttctggc
    11581 ttcttctttg gcctccaata gtgcttcttt tttaagagac ttgctttcac gtttagcttc
    11641 attaacaagt aaatccgctt cacgctcagc ttgtccacgt aaattagttg cttcttgttc
    11701 agcatttaaa agcatcaact ccgcagcttc ctgagatgat ttcatcttag ctgagatgct
    11761 gacatatcca atgactaaac caatgatgac ggcaaaaaca gcaatcgcaa gcgacatgat
    11821 ctccatgttt ttacctcatt ttattgttat tccgaatgac atacattctt ttacattcta
    11881 ccataaaaaa gtgattttca caaacctaaa atagaatatg ttttggggaa attagtctga
    11941 attttaggat tacacttcct tggtttttta aggagataag tcagtgccgc tatcaaaaag
    12001 ttccaccgaa tttctaccgc tatggatttt ctattgttgt gccaaatagt gttccactag
    12061 attcaaacat tttgctttca agtctttgaa aattcacttt aggaaatcac agcttatctt
    12121 caagatcaaa tttgtcataa attaactttt ttatttagtt gtatcaattt atttcttaag
    12181 tattaattta tcctcatcga aagcttttaa aatatactca ttaatcaatt tattatcttc
    12241 ttcatttttt gaaaaataag ttttaatatt attgggagtt ctatgttcta gtagacgatg
    12301 gataacatca tcacttctat catggaacca ggtccaatct acttcaggat aaagtcctcg
    12361 aatatcttct tcaatatctt ttaaaatctc aaaatcagaa aaatatcctt ttctacttaa
    12421 gttgtataaa tctgatacag acttttctct tgggtctggg aaagttttaa ccccctcaac
    12481 tcttttatca ttaattcttt taatcaaata atggtagatt ttattttgta tctgaggaaa
    12541 atcatagaca ttataactca tcaaatcaat tactttatgg taaataatat tttctgattc
    12601 ttcataaact tttagagtat ctaaaatgtc atctttaata tccttttcaa aatacttaaa
    12661 taagtgacat atcaagtcag aatattctat gatatttttt atatcatcat ttttatattt
    12721 tattcttaaa atatctgtat taaatttttc gagtactatt attgcagttt cctgatcagt
    12781 tgagcagtat tctagtaact gtgaatagag cggatacact gaattatata aagaaaaatt
    12841 tttctccaaa atttcattta aatgtttatt tacaatccca attatcttag atttcaatga
    12901 atctttatca ataacatcca tattatcgag gacaatttta ataattctcc taaattcctc
    12961 gctccaatta taatacagtg tttgattatt taaaatttct attacttttt ctatgtcaat
    13021 atcatcaaca aggggaagaa aaattagcat atttttaagc tctcgaagat tttcatcttc
    13081 agtaatttca agtctttctt gaagataagt aattcgattc aacaagtagt ctttcgcttc
    13141 ctcagtaact tttattttac caaatgaata gtttctaaaa tataaattta caaccttaaa
    13201 atctatattc ggaagaatta atttaacatc atccaaatca agatttttaa gccaagaaga
    13261 tgttctatcg aaaatacttg agtcagggtt tacatatgaa ttatcataac tgagtaataa
    13321 tatttctaaa tatctattaa tgattgattt ataaatctta taatgttcaa cacataaaca
    13381 atttaatttt aaaaagttat aaagattttt tactgtaaac tccgcattaa atagatgatt
    13441 attagcagac catcctcctc ttctatagct ttcatgctct tcacgaattt catcaaataa
    13501 ttcattaata gtttctaatt ttctatataa aaaattgaag ttaaggattg aatctctaaa
    13561 aaattctata atctttttct catctcctgt aaccgagtta agaatttgtt ctgttaattc
    13621 gcttaattct ccatcataaa gtggctctgc ataactaggt gttttttcgt atctatcaat
    13681 tatttgaatt tgctgaaaat taaattcaca aactaagaaa ttaaaatagt ctttctgacg
    13741 aaatgctata ttagctagtt ctctaaattt tgcttttgct aaagaatatt gtttttcttc
    13801 atacaactta aaagccttac ttaagaatcg attccccttt aaatccctag gctcaccaat
    13861 ctccatatct agaaagcgat ttaataaaga ttttttagat accataattc gtaattcttc
    13921 atgaccatca atttcaaatc ttaattgatc atttccaaac cagcaatact catcatccca
    13981 gtttaaagcc cttttcttta aatcagaata tctagaaaaa tctttcgcat caataaaact
    14041 aagtctatct aaaaaagcca gttgattcca taaatcatca gcattattta catcttgact
    14101 tcggttttct gatagaacct ctaaaaaatc ttttgtcctg caatacaatt tgttctgttt
    14161 ttctgatgtc tcctgaccta gattctcttc attagagata atgaaaattc cttgcttctt
    14221 ataatactct cgaatgatca tagacggttc ctcgggagta taaaaataag catttttagc
    14281 atccaattta aatgtatttt gaatcattct aaaaattgaa ttaaaagtcg aatcacttag
    14341 agaatacccc acaaacaata gagtatgatt cattatcaat gactggatta aagtagaaat
    14401 cattgggaag ttcaaatgat agtctaaata atcatcttct ttcaaaacaa tatttttctt
    14461 actgaagtca ccatgcattt taatcaagta tctttccgaa ctcgtataag ggatgtcttt
    14521 atcctcagcg actacattgt actttaacaa gccactttca aattgactct ccagaagtga
    14581 atcatagttt gtcgtaataa tatgttttgg tgcaattttt tctattaatt tatgtaactc
    14641 atttggttta ctcaatccct tcttaaagaa aatttcttct atcttctttg tgtactgatt
    14701 tttcccaaaa gtatcataat aatactgagc aattctcagt ggactatctg ttctttcttc
    14761 tggtatgttc aattcttttt ttaatgattg aatcaattct ccccaagttg gtagattaga
    14821 attagctgat attcctgcac caacaaacaa aactaaggaa ttttctttaa tagaattctt
    14881 tatttgagtt atagataaat tataattttc ttccatattt taactatcct acattagctt
    14941 gtactacata aatacaaatt atccttataa atcttctttt ttattacata atcttaaaca
    15001 aaagtttatc atggtttata aatataaaaa tttatttgtc ttttatattc aatttatgat
    15061 tattaatata accagttctc ttcattatac cacaaaataa caagcataaa gcggattcaa
    15121 agataaagat taaggttcat atactaattt tctttattga ctttttgtct tctgtattag
    15181 ggagtttatc attttccaaa aactttatct tcaatttgtt atctaaaatt tctacaataa
    15241 aaaagcctac ctttcagtag acttagtttg tttctattct aatcggcact ctgccaaaat
    15301 tttgctctgc tatacttggc tttcctagtt ggtaaatctg gtcaaccttt tgagtcatag
    15361 catcccaagg ttctttgcca attcggctga ctagattgac ctgtcctttc agagacttga
    15421 gatgttgcct gcctttttca gtaaatccaa ggacatgaat ggcttctggc aagacatttt
    15481 ctctagcctg taccaaaata taggtcaata ggcgtctgac acgcgccttg gtgtaacgtt
    15541 tggtagtcac taactcgacc aattcttcca cagactgggc tgttttaata gcttctttaa
    15601 tgcgcacagc catttcttga ttgacctgat agatggtggt taggtcggga tttgacaaga
    15661 tttgatagcg gagcaaggga aaatagtctt cccagatcac cttactggcc tgctcaaata
    15721 gggcaacaga aggcataaaa cgttctaaga aatcttggtc cttctgatgt tgacggaggg
    15781 ctgtcgccga ggcaaagtcc acatctttat tcacagaatg gtaacctgcc ccctgacgct
    15841 gaatcggatg cagcttgata tttcgtcctg caaccgcctt tgcataggcc agagcaagaa
    15901 catgattggg ggtattacct gaaaaatcaa gaccagcaaa ttccttccac atagcttggg
    15961 ttttctgggg ataggaaagg gaatcaggca gatttttcac aaatttctcc atctcagcac
    16021 ctttctctgt gtataagtca gcgattttct ggtaatccag aacttcctct gtcccaaaaa
    16081 ctagactatc aatgcccaag cgatccaaga tatccacagc tccttgacca aagaaatcag
    16141 ctgcctgaac actgactaaa aagggcaatt ccactaccaa gtctgcgcca ttttccagcg
    16201 ccatctgggc ccttgtccac ttatccacaa tagcaggctc tccacgctgc atgaaattcc
    16261 ctgacatggc aacaattttc agtccctctg cctgatccag caggtattta tggccattat
    16321 gaaaaggatt gaactccgcg ataatacctg ttatggtcat gctaatctcc tacttctgcg
    16381 ccacaaaaaa ccaacgggtg ctagtttctg ttggctcctt atcctcaaag tctgcataga
    16441 gtttgaagga cttgaatcca gcctgttcca gcaagatctc ataggtcaag atctcatagg
    16501 tcctctcctc atgtacttca tcgtggcgac taaaggaacc atcagcctcc ttgataaaga
    16561 aagtcagctc atggacgatg gagtgaggaa cttcgtcctc atatgtatcc caaagcatgg
    16621 caaaatcttc cgcattttca tggtaggaat agccagggaa tacttcatct gtctggtagg
    16681 tcgagtgcac gtcaaagatg aaaactccct cttcattcag cgcattgtac acgtccttaa
    16741 agacgtcccc tacttccacc tcatcctgca tatagcagat agagtccgaa taacacgtga
    16801 caaaatcgta tttccctgcc ttggacaaat tcagcatatt accttctata aaagcaatct
    16861 tttgcttggc tgaagttgct ctcttctccg caatcttcaa catatccgca ctcaagtcaa
    16921 gtccagtcac atcaaaacca gcctgagaga agcgcactga ttgaattcct gtcccacaag
    16981 ccaattccaa gagtttcttt ctctccttgg tcttaggcaa atgacgcaga gaaaaattcg
    17041 tccatttgtc gtataaacta tcgtccatga ccgcatcata gaccgccgca aaggtttcat
    17101 aagtcgccat aatcatgata ctaagagctc catggtaaac accactagcc ctttaccttt
    17161 ctatcaattt ttctaaaata agcaaagaaa cccagttgac tacaactgag ttcatcttct
    17221 aagcaagagc ttctgaaata tctactgaat tcgcctcatg ccatagcttc tctagattat
    17281 aatgggcacg catttcttct gaaaagatat gcacgacaac agcaccgagg tccagtaaga
    17341 cccagcctcc agctgcatcg ccttcgatat ggctaccttt aaagcctgct tgagctactt
    17401 tttcacggat attagctgcg atagcgtcca actgacggct attcattgag ctagtgatga
    17461 caaagtagtc cgtcacacta gtcaaatctt gtacatcaag tgcgaggata tcctccgcac
    17521 gtttctcatc agccgctttc acgactagtt ctagtaattc tttttcgttc atttaatcct
    17581 ctttttagaa aatatgtttg taatctagaa catctgcaaa gcactcctcc caaatgtcct
    17641 cataaaattc attaatcgtt tctgctggaa tgtcatcccc atcaaaggtt gtgacagcac
    17701 cttctggaac aataagctga tagccatatt caaaggcaac cttgacagag gtatccacac
    17761 aatattctgt ctgcatacca cataaaacta atttttcaat cccctgttta tccaagtatt
    17821 cttttaagcc agtttctttg aaaatactgt tatacttctt ctgaaagacc ttttcagcag
    17881 gttttcgatt taaaagcgca gataactgcc aatcttctga tgtttgagct tcagaattct
    17941 caatatgttg aacatagata atttcaatat tcttgcttct agcctggttt tgtaaataag
    18001 aaattttttc caatagactt tttgtctgga acccagtttc tactaaaaca ttctgaacat
    18061 caatgattat aaaagccgtc ttcatttagt cctctttcaa atagtgcaca aaggcgttat
    18121 aggtttcaag ggtttgggga tagatgggga atccctgatg agctagatac tccacggtac
    18181 gagctgtttc gtaggccacc gccttattga gcgatagact tgcaatctca cgcgccacat
    18241 ctactccagg aaaggctcga ttgtgctcga tatagtctgc gacgtagatg accttatcta
    18301 ggtctgtcat ttgaccagca ccgactgtat ggacttcaat ggctcgcagg atttctgaat
    18361 catgcaaatc caaatcttcc tgaattttgt aaattccgac cataccatgc cagacattat
    18421 taccccagtt tttgaggtcg aaatctagct gataacggtc aatcaagtct agaaattcct
    18481 gatctgacaa ctttttagca tagtcatgaa gaagacctgc tagacttgct ttctcaacat
    18541 ctacaccaaa gcgctgagct aactccatag cggcacgctc cacacctaga caatgggtta
    18601 gacgtttctc aggtagaagc tctgccattt tttccaacaa ggcctcacgg gagcagttga
    18661 tatagtcttg ataggacatc agtagagccc ctccttctcg atgtagtcta gcactggctg
    18721 aggtaggaga aagttgggtt tccgaccttg ggcaatgaag tcccgcacca tgctggacga
    18781 gatatccatg agcggtacgt ccacccagat aactggatag gaagtccctg ccttgtagcg
    18841 tggacgctga acccccacaa actgaaccat gtcaaccagt tcatcaattc ggtaccactt
    18901 aggcagatag tcaaccatgt cggcaccgat gataaagtaa taatccgtat ctggatgttg
    18961 ctctgtcaag attttcatgg tgtcgtaggt gtaggaaata cccttgcgct ccaactcaat
    19021 ggtttcaatg actaggccgt caatcccctc aattgccaac tcaagcatct tgagacgatg
    19081 gtgttcaggg atggtttcct ttttatcaac gtgaggaggt tggtattcag gcatgagaag
    19141 aacttgatcc agtcccaact gttgccgtac ttgatccgca acaatgagat gggcattgtg
    19201 aacagggtta aaattccccc ctaaaatccc aacttgtttg cgttttttct ccttgatttc
    19261 tggctccaac tctaccttgg taaagggagt caatagttcg attgtcatag gctagtcccc
    19321 tttatttctc tataaaaaca gttatttgga gtttcggtct tagatttctt tgactttctt
    19381 agaaatcttg cgattttctt tcttgctaga ttgtttaaac aaaatcaaga tgcgtcctat
    19441 tttttggact gtatccacac cgatttcttc ttccaaaatt tcagctactt cgtggatatt
    19501 ttcatctgtg ttttgtaaga gagtaacctt gattaattca cgcgcatcaa gagcttgacg
    19561 gacgctggtt ttgatttggt cgttgagtcc atttttcccg atttggatga taggtttgag
    19621 ggtgtgtgcc tggctgttga ggaaggcacg ttgttttgat gttaatgaca taattttctt
    19681 ccttgttttt ggatagttat tttaggtggt gagggacggt cggaactaat tttccaaaga
    19741 tttcatcttt gaaaaatgga tttcctgacc tcacaattga gccttggtct caattgtgcc
    19801 ccttgccaat ctacagattg gcaatcacac cacggcaata actatcgcta tatgagctca
    19861 ctttgttcgc tcagcgattt tgttttaaat aattgctttt cgtgtgacga cggcgacgcc
    19921 ttctggtgcc cagacggcga cttttgctat gcctgttaca cgaatccagc ctaggcctga
    19981 gatgactagg tctgtcttat ctttaatggt aaagacatgc tggactagcc ttgggaaatc
    20041 ttctttttcc ttgctatttg gtggtgtcag aagagttccc aggtgcttat cgtagaaagc
    20101 actagctcct tcaaacttgc tacgatggag tttgagttca ttatcaaaga aagcagtaaa
    20161 tccttgcttt tctcctgcta taaagtcaaa gcgtcccaaa ccacctaaaa atagggtttg
    20221 ctcaggatta agctgatagg tcttaggctt gatttccttt ttaggactga catacttgag
    20281 gtttttggcc gtcaagtagt gagccatctg gtggcggtgg ataattcccg gcgtatcgta
    20341 aatataagat ccgtcgtcaa gcggaatctc tattttgtcc aaggttgtac ctgggaagcg
    20401 tgaagtagtg atgacattct gatcacccgt gatttcttgg ataatagcat tgattagagt
    20461 tgattttcca acgttggtca caccgaccac atagacatcg cggcccttac ggtagtgttc
    20521 aatcttgtca atgacttcct taatggcatg tttattttgt gctgaagtta ggaccacatc
    20581 gactggacga agaccttctt catgggcacg tttcatgagc cactggctaa tcttaccaga
    20641 cttaactgac ttaggaagga tatctttttt atttcctacc aagaggacat cattgcccga
    20701 gacgaaacgt ggtaaacctg ggatgacaga tccattaaaa tcaaagatat caatgacatt
    20761 gaccactaag gcatcactgt ctcccacctc gtgcaagagc ttgaggaaat catcgttcgt
    20821 caactggaca tctgtgattt cattgtagtg gcggagacgg aaacagcgtt ggcaatagac
    20881 ttcgccagtc tccaaacctt tttcaagtgc cgactggggg gtaaaaccaa gaccagcttt
    20941 atctgtcgtc tgaatggttg ctccacaacc aatacagaga atttcttcca tagttaaatt
    21001 ccttttttat atgtaatcgg tccgtacttt tcagtgattt ttctcataac acgacgctca
    21061 cgagttcggt taatctgcgt tttgattgag tcatgttgga ccaagggttt gactaaaatt
    21121 gaccgaatcc ctgcacggtg ggctgctcgt atatctgtca tgagctggtc gccaaccatg
    21181 accacttcct ttttgtcata gtggaattcc ttcatagcac ggtcaatacc aaatgtgaag
    21241 ggcttcaagg cccagtaaac gtaatcaatc ccaaatttct caactgctcg ttgaacgcgt
    21301 tttttggtgt tatttgacac tacgataatg ccaatacccg cgtcccgaag gtcatgtagc
    21361 cattgcttca tctctggcgt tccatcaggg ttgttccaag caatgagggt attatccaaa
    21421 tcgaccaaaa cagccttgat tccctgcgcc tgcaggcttg ggactgtcag atcatagact
    21481 gcttccacag caaaatctgg tatataattt tcaatcgcca ttctggctcc ttttcttaac
    21541 tttttttcgc aattttcctt agtaacaagg ataaaacaat ccacaaacct gcactagcca
    21601 aactgatata gagccaagca tggggctcat ctgttaaagg taagggaaca ttcattccga
    21661 aaaagcctgt cacgactgcc aaaacagcta gcaagactga aatgatagtc aaggttgtca
    21721 aattgtcatt cagattattg tttagaatat tgttgtaaga ggctgaaagc tgctgtaaaa
    21781 tctgagagat taggtctgtc atggatacca gctgatgagc ctcaatcatg gcatcatcaa
    21841 actgttctct ctcaatctca tcaaaactac gatacaaggc atgaccttga atatgctcta
    21901 acaaaatccg attttgtttg gcagctgccg tcagataaac cataccagtc tccaaatcag
    21961 acagggcaaa gaggtttttc ttggtagttc gctggcgcaa gaggtcattg acctcatccc
    22021 tactcttgtc catctgctca atgacaggat agtaggcatt gctgataatt tccagactgg
    22081 caaagagaaa cttataaatc gaaagcgtgt catggctctc cagataacga gtcatctgtt
    22141 caatgacata ggcgttcttg gtattactaa tggtaatcag gcgacgatgc tcgacaataa
    22201 aggtcatggg aaaagtctca tagtaggcct tgtccttttt tacgtctagg acattataga
    22261 taaaggtaac cgtcccactt tcacggtggt aatccatgtg ggcgcgctcg tttctatcca
    22321 gtgcgtattc aatggtttcc ttgtccaaac cgtaaatttc agaaaggtct tctagtttat
    22381 tcaactttcc taggtctagg tctatccagg tacaaccatt gcccaactgc ttttctaaaa
    22441 ccatcttttc tccttattaa actccctcta ttgtaccaca aattacttaa aataacaggt
    22501 ctagtctgtg cgtgagaaat tgctaacaac tgtgatattt cggttaggga caaagtgaag
    22561 ggcttgctcc tcgctacgaa gctgtgtcgt acgaattccc acactgacaa ccttacccga
    22621 tacagtaatc ggtccatttg tcagaacgac ctcatctccc acatccagtt gacgttcaaa
    22681 gaggatgaaa aagccattga tgacatcaga cagaaagcct tgggctccca taccaatcgc
    22741 taccccagca ataccagctc cagccagcaa actagaaact ggcaaaccta aaatcgacaa
    22801 aatgcagtag agtaaaaaga aatatagcgt ataattaaac acattttcta gtaaacgtga
    22861 gatggttttt tggcgtccga catcatgacg agacattttt agagaaggtt tgacaattct
    22921 ctgcaccatg gtatgaagca tttttttagc aatataaaat acaatcaaaa gcagtaaaag
    22981 agaaatgacc ttggttagaa tattctcgat aatggttgtc acatctagct tttcaatata
    23041 agcctgaata aatttttgca tataaaactc ctttatttca ttataccata ttttcatcag
    23101 tctcattctc cataaatatt caaaaaatag acagaaaatt cttgattttg tctatcattt
    23161 atactataat cataatcact acacaaaaag gagattatta tgaaaagaat cattcatgct
    23221 tggaataagg caagccttgt caagcgtatc ttgattggta tgctttgtgg ggaatcctag
    23281 gactgaccct tcctaatctc tcagggattg ggctactcgg ggatttattc gttggaggtc
    23341 taaaagctgt tgctcctatc ctagtctttg ccctcgttgc caatgccctt tccaacatca
    23401 aaagggacaa gatagcaata tgaaaactgt tgttttcttg tatatcctat gatagggact
    23461 ttcgccgctg ctcttgtagc tgtactagca agtttcatcg tccctattga aattacccta
    23521 aatagtgcca atactgaaat tgcaccacca gatgggattg ggcaggtcct cagcaacctc
    23581 ttgctcaaac tggttgacaa cccagtcaac gccctgctta ctgctaacta tattagaatc
    23641 ttatcttggg cagtcatttt tggaatcgct atgagagaag ccagtaaaaa tagtaaagaa
    23701 ttgctaaaaa ctatcgctga cgtgacttct aaaattgtcg aatggatcat caatctggct
    23761 ccatttggaa tccttggtct tgtttttaaa accatttctg acaagggagt cggaagcctt
    23821 gccaactacg gtattttatt ggttctatta gtaacgacta tgctttttgt tgcccctgtg
    23881 gtcaaccctt tgattgcctt cttctttatg agacgcaatc cttaccctct agtttggaac
    23941 tgcctccgtg tcagcggtgt gacagccttt ttcactcgta gttctgcgac taacattcct
    24001 gtcaacatga aactctgcca tgaccttgga ctcaacccag atacctattc tgtttctatc
    24061 ccactcggtt ctactatcaa tatggctgga gtagcgatta ccattaacgt tttgaccctt
    24121 gttacagtta acactcttgg aattcctgtt gactttgcca cagcctttgt cctcagtgtg
    24181 gtagcagcta tctcagcctg tgatgcttca ggtattgccg gaggttccct ccttcttatc
    24241 ccagttgctt gtagcctttt cggtatttct aacgatattg ccatacaaat tgttggggtt
    24301 ggttttgtga ttggtgtcat ccaagactca tgtgaaacag cccttaactc ttctacagat
    24361 gtcctcttta ccgccgttgc cgaatacgca gcaacccgta aaaaataact catcaaggca
    24421 agcctgctca tgtcttgtct tttacgcttt tattctaact tattaggaaa ttcttatgtc
    24481 tattagccaa cgtacgacca agctcatctt agctacctgt cttgcctgcc tgcttgctta
    24541 ttttctcaat ctttcgtcag cagtttcggc tggaattatc gctctcttga gcctatctga
    24601 tacgcgtaga agtactttaa aactggctcg caatcgtctt ttttctatgc ttctagctct
    24661 ggctatcggc gttctagctt ttcacttgag cggatttcat atctggagtc tcggcctcta
    24721 tctggccttc tacgttcctt tagcctacaa gatgggctgg gaaattggca tcacaccaag
    24781 cacggttttg gttagccatc tcttggttca agagtcaacc tctccagacc tcctagtcaa
    24841 cgaattcctt ctctttgcta ttggtacagg atttgccttg cttgttaatc tctatatgcc
    24901 ttcacgagaa gaggaaatcc agcactacca cacgctggtg gaagaaaagt taaaagatat
    24961 cctccagcgc ttcaaatact atttatccag aggagacgga cgcaaccgag cacagctggt
    25021 agcagaatta gacacgcttt tgaaagaagc cctcagactg gtctatttgg atcactctga
    25081 ccacctcttt caccagaccg actaccatat ccactacttt gagatgagac aacgacaaag
    25141 tcgtatcctg agaaacatgg cccaacagat taacacttgt caccttgccg ccagtgaaag
    25201 cctgatctta gcgcaactct tttcaaaaat tgcaggtcaa ctgagccaga ccaatcctgc
    25261 ttctgatttg ctagatgaaa ttgaacgtta tctggaagtc ttccggaacc gcagtctgcc
    25321 caagacaaga gaagagtttg aaacccgcgc cactcttctt caactcctac gtgaagccaa
    25381 aaccttcatc caagtaaaag ttgattttta ccaaaaatat agacagtaaa aaagaaaacc
    25441 actaaaaaac agagcttgcc agtattcttg aaaagtagta taattattgc atgcgcaatc
    25501 atcttgtgac gcagagactg cccgttaatg gactttcttc tatttatgac tctaaaaaga
    25561 aaggagacac tatgacctat ttggaaaaat ggtttgactt caatcggcgt cagaaagaaa
    25621 ttgaaagtct cttggaagag accattgccc aacagagcga gcaaagtctg accttgaaag
    25681 agttctacct gctctactat ctggacttgg ctgaagaaaa atctctacgc cagattgacc
    25741 tgccagataa gcttcatctg agcccgagcg cagtttctag gatggtggct cgcttggaag
    25801 ctaaaaattg cggtctactc agtcgcatgt gttgccatca agatagacgc tctagtttta
    25861 tctgcctgac aaatgatggg caaaagacac tggcctcgct acaaaagact gtcgaagaaa
    25921 gcttggaagc aggtttggat ttcttgattt aagatgattt taaaaaaagt tgcgtgcgca
    25981 atcatttttc ttgacattct cttttataag gagtaaaata aagttagcat taaacaaagg
    26041 agttttaaat atgattgaaa ttacctatat agatgccagc aagaacgaaa gaactgtgac
    26101 tttcgagtct tatgaagact ttgaacgttc gcaacaagct tgccttatcg gcgtcgcaga
    26161 ctactaccct gtccaaaaat taacttacaa gggtcataat ttggactacc atgggactta
    26221 tggagatatc ttcttctatc tcatgaaaca agatttaagc caatataact aaaaaaagga
    26281 gaaatacaat ggcaaaagca attacagatg caacattcga acaagaaaca aaagacggtt
    26341 tggtcttagt agacttctgg gcaacttggt gtggtccatg tcgtatgcaa ggtccaatct
    26401 tggacaaatt gtctgaagaa ctttcagaag atgtcttgaa aatcgttaaa atggacgttg
    26461 atgaaaatcc aaacacagct cgtgcttttg gaatcatgtc tattccaact cttctcttca
    26521 aaaaagacgg ccaagttgtc aaacaagttg caggtgttca cacagcagaa caaatcaagg
    26581 ccatcattgc tgaattgagc taatcaaacg agagaccaag tactttcttt ggtctctttt
    26641 ttcttgctct ttgccatttt tcaaaaaata tgctag
//
LOCUS       DAVBOG010000028        26014 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.028, whole genome shotgun sequence.
ACCESSION   DAVBOG010000028 DAVBOG010000000
VERSION     DAVBOG010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 26014)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26014)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26014
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.028"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(15..311)
                     /locus_tag="VQ865_001284"
     CDS             complement(15..311)
                     /locus_tag="VQ865_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000239014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135616.1"
                     /translation="MVKINKICSIQGSSVENEDIVGSQNQYFWIIGGATDLYNSKEEI
                     GYSVSEVVHILSESLSVNCKESKTLKQIFETALLEVKDEIGLNSYELTEYSKMK"
     gene            complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ865_001285"
     CDS             complement(295..2454)
                     /gene="pfbA"
                     /locus_tag="VQ865_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multi-ligand-binding adhesin PfbA"
                     /protein_id="HET3135617.1"
                     /translation="MLKIVKKLEVLMKYFVPNEVFSIRKLKVGTCSVLLAISILGSQG
                     ILSDEVVTSSSPMATKESSNAITNDLDNSPTVNQNRSAEMIASNSTTNGLDNSLSVNS
                     ISSNGTIRSNSQLDNRTVESTVTSTNENKSYKEDVISDRIIKKEFEDTALSVKDYGAV
                     GDGIHDDRQAIQDAIDAAAQGLGGGNVYFPEGTYLVKEIVFLKSHTHLELNEKATILN
                     GINIKNHPSIVFMTGLFTDDGAQVEWGPTEDISYSGGTIDMNGALNEEGTKAKNLPLI
                     NSSGAFAIGNSNNVTIKNVTFKDSYQGHTIQIAGSKNVLVDNSRFLGQALPKTMKDGQ
                     IISKESIQIEPLTRKGFPYALNDDGKKSENVTIQNSYFGKSDKSGELVTAIGTHYQTL
                     STQNPSNIKILNNHFDNMMYAGVRFTGFTDVLIKGNRFDKKVKGESVHYRENGAALVN
                     AYSYKNTKDLLDLNKQVVIAENIFNIADPKTKAIRVAKDSAEYLGKVSDITVTKNVIN
                     NNSKETEQPNIELLRVSDNLVVSENSIFGGKEGIVIEDSKGKITVLNNQFYNLSGKYI
                     SVIKSNANGKEPVIRDSDGNFNIVTENGLYKIVTNNLSDKNEKEKNKEEKQSNSNNVI
                     DSNQKNGEFNSSKDNRQMNDKIDNKQDNKTEEVNYKIVGDGRETENHINKSKEIVDVK
                     QKLPKTGSNKIMELFLTVTGIGLLLTLKGLKYYGKDK"
     gene            complement(3584..4810)
                     /locus_tag="VQ865_001286"
     CDS             complement(3584..4810)
                     /locus_tag="VQ865_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001134527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegT/DnrJ/EryC1/StrS aminotransferase family
                     protein"
                     /protein_id="HET3135618.1"
                     /translation="MPNYNIPFSPPDITEAEIAEVADTLRSGWITTGPKTKELERRLS
                     LYTQTPKTVCLNSATAALELILRVFEVGPGDEVIVPAITYTASCSVITHVGATPVMVD
                     IQADTFEMDYDLLEQAITEKTKVIIPVELAGIVCDYDRLFQVVEKKRDFFTASSKWQK
                     AFNRIVIVSDSAHALGSTYKGQPSGSIADFTSFSFHAVKNFTTAEGGSATWKANPVID
                     DEEMYKEFQILSLHGQTKDALAKMQLGSWEYDIVTPAYKCNMTDIMASLGLVQLDRYP
                     SLLQRRKDIVDRYDSGFAGSRIHPLAHKTETVESSRHLYITRVEGASLEERNLIIQEL
                     AKAGIASNVQYKPLPLLTAYKNLGFDMTNYPKAYAFFENEITLPLHTKLSDEEVDYII
                     ETFKTVSEKVLTLSKK"
     gene            complement(4853..5545)
                     /locus_tag="VQ865_001287"
     CDS             complement(4853..5545)
                     /locus_tag="VQ865_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000922225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HET3135619.1"
                     /translation="MLKWEDLPVEMKSSEVESYYQLVSKRKGSLIFKRCLDWVLALVL
                     LVLTSPIFLILSIWIKLDSKGPVIYKQERVTQYNRRFKIWKFRTMVTDADKKGNLVTS
                     ANDSRITKVGNFIRRVRLDELPQLVNVLKGEMSFVGTRPEVPRYTEQYSTEMMATLLL
                     QAGITSPASINYKDEDTIISQMTEKGLSVDQAYVEHVLPEKMRYNLAYLREFSFFGDI
                     KIMFQTVFKVLK"
     gene            complement(5731..7482)
                     /locus_tag="VQ865_001288"
     CDS             complement(5731..7482)
                     /locus_tag="VQ865_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135620.1"
                     /translation="MQNKQEQWAVLKRLMSYLKPYRLLTFLALSFLLATTVIKSVIPL
                     VASHFIDQYLSNLNQLAVTVLLVYYGLYILQTVVQYVGNLLFARVSYSIVRDIRRDAF
                     ANMEKLGMSYFDKTPAGSIVSRLTNDTETISDMFSGILSSFISAVFIFLTTLYTMLVL
                     DFRLTALVLLFLPLIFLLVNLYRKKSVKIIEKTRSLLSDINSKLAENIEGIRIIQAFN
                     QEKRLQAEFDEINQEHLVYANRSVALDALFLRPAMSLLKLLGYAVLMAYFGYRGLSIG
                     ITAGTMYAFIQYINRLFDPLIEVTQNFSTLQTSMVSAGRVFALVDERTYEPLQENGQA
                     KVQEGNIRFEHVCFSYDGKHPILDDISFSVNKGETIAFVGHTGSGKSSIINVLMRFYE
                     FQSGRVLLDDVDIRDFSQEELRKNIGLVLQEPFLYHGTIKSNIAMYQEISDEQVQAAA
                     AFVDADSFIQELPQGYDSPVSERGSSFSTGQRQLLAFARTVASQPKILILDEATANID
                     SETESLVQASLAKMRQGRTTIAIAHRLSTIQDANCIYVLDKGRIIESGTHEELLALGG
                     TYHKMYSLQAGAMAYTL"
     gene            complement(7472..9217)
                     /locus_tag="VQ865_001289"
     CDS             complement(7472..9217)
                     /locus_tag="VQ865_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3135621.1"
                     /translation="MSIIQKLWWFFKLEKHRYLVGIVALVLVSVLNLIPPMVMGRVID
                     AITSGQLTQQDLLLSLFYLLLAAFGMYYLRYVWRMYILGTSYCLGQIMRSRLFKHFTK
                     MSPAFYQTYRTGDLMAHATNDINALTRLAGGGVMSAVDASITALVTLLTMLFSISWQM
                     TLVAILPLPFMAYATSRLGRKTHKAFGESQAAFSELNNKVQESVSGIKVTKSFGYQAD
                     ELKSFQAVNELTFQKNLQTMKYDSLFDPMVLLFVGSSYVLTLLVGSLMVQEGQITVGN
                     LVTFISYLDMLVWPLMAIGFLFNTTQRGKVSYQRIENLLSQESPVQDPEFPLDGIENG
                     RLEYAIDSFAFENEETLTDIHFSLAKGQTLGLVGQTGSGKTSLIKLLLREYDVDKGAI
                     YLNGHDIRDYRLTELRSLMGYVPQDQFLFATSILDNIRFGNPNLPLSEVEEATKLARV
                     YQDIVDMPQGFDTLIGEKGVSLSGGQKQRLAMSRAMILNPDILILDDSLSAVDAKTEY
                     AIIDNLKETRKDKTTIITAHRLSAVVHADFILVLQNGQIIERGRHEDLLAMDGWYAQT
                     YQSQQLEMKGEEDAE"
     gene            complement(9423..9719)
                     /locus_tag="VQ865_001290"
     CDS             complement(9423..9719)
                     /locus_tag="VQ865_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HET3135622.1"
                     /translation="MSASDVALKLRSQGIFQMKQVKRAVQEQNGQLIVVQMGDENPKY
                     PVVTDGVIQVDVLESIGRSEEWLLDNLSKQGHDNVANIFIAEYDKGAVTVVTYE"
     gene            complement(9872..10328)
                     /locus_tag="VQ865_001291"
                     /pseudo
     CDS             complement(9872..10328)
                     /locus_tag="VQ865_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730499.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3290 family protein"
     gene            10461..11288
                     /gene="xth"
                     /locus_tag="VQ865_001292"
     CDS             10461..11288
                     /gene="xth"
                     /locus_tag="VQ865_001292"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HET3135623.1"
                     /translation="MKLISWNIDSLNAALTSDSARAKLSQEVLQTLVAKNADIIAIQE
                     TKLSAKGPTKKHVEILEELFPGYENTWRSSQEPARKGYAGTMFLYKKELTPTISFPEI
                     GAPSTMDLEGRIITLEFDAFFVTQVYTPNAGDGLKRLEERQVWDAKYAEYLAELDKEK
                     PVLATGDYNVAHNEIDLANPASNRRSPGFTDEERAGFTNLLATGFTDTFRHVHGDVPE
                     RYTWWAQRSKTSKINNTGWRIDYWLTSNRIADKVTKSDMIDSGARQDHTPIVLEIDL"
     gene            11300..11443
                     /locus_tag="VQ865_001293"
     CDS             11300..11443
                     /locus_tag="VQ865_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3135624.1"
                     /translation="MDYNAVIPELLVSNIEQSRSFYCGLLGFRIEYQRPEENFLFLLK
                     SVN"
     gene            11443..11682
                     /locus_tag="VQ865_001294"
     CDS             11443..11682
                     /locus_tag="VQ865_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HET3135625.1"
                     /translation="MLEEGTKDQLAELTYPFGRGVNLSFGIKDVSKLYQRVMKANYPI
                     YRPLTKRKFRVSDPYIYPHEFAVLDPDGYFLRFSE"
     regulatory      12065..12160
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            12560..13141
                     /locus_tag="VQ865_001295"
     CDS             12560..13141
                     /locus_tag="VQ865_001295"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000770427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HET3135626.1"
                     /translation="MKLLEERILKDGHILGDNILKVDSFLTHQVDFSLMREIGRVFAE
                     KFAATGITKVVTIEASGIAPAVFTAEALNVPMIFAKKAKNITMNEGILTAQVYSFTKQ
                     VTSTVSIAGKFLSPEDKVLIIDDFLANGQAAKGLIQIIEQAGATVQAIGIVIEKSFQD
                     GRDLLEKAGYPVLSLARLDRFENGQVVFKEADL"
     gene            13141..14403
                     /locus_tag="VQ865_001296"
     CDS             13141..14403
                     /locus_tag="VQ865_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001194492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HET3135627.1"
                     /translation="MQTQEKHSQAAVLGLQHLLAMYSGSILVPIMIATALGYSAEQLT
                     YLISTDIFMCGVATFLQLQLNKYFGIGLPVVLGVAFQSVAPLIMIGQSHGSGAMFGAL
                     IASGIYVVLVSGIFSKVANLFPSIVTGSVITTIGLTLIPVAIGNMGNNVPEPTGQSLL
                     LAAITVLIILLINIFTKGFIKSISILIGLVVGTAIAATMGLVDFSPVAVAPLVHVPTP
                     LYFGMPTFEISSIVMMCIIATVSMVESTGVYLALSDITKDPIDSTRLRNGYRAEGLAV
                     LLGGIFNTFPYTGFSQNVGLVKLSGIKKRLPIYYAAGFLVLLGLLPKFGALAQIIPSS
                     VLGGAMLVMFGFVSIQGMQILARVDFANNEHNFLIAAVSIAAGVGLNNSNLFVSMPTA
                     FQMFFSNGIVVASLLAIVLNAVLNHKKK"
     gene            complement(14490..15356)
                     /locus_tag="VQ865_001297"
     CDS             complement(14490..15356)
                     /locus_tag="VQ865_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II restriction endonuclease"
                     /protein_id="HET3135628.1"
                     /translation="MKQTRNFDEWLSTMTDTVADWTYYTDFPKVYKNVSSIKVALNIM
                     NSLIGSKNIQEDFLDLYQNYPEILKVVPLLIAKRLRDTIIVKDPIKDFYFDFSKRNYS
                     IEEYTMFLEKSGIFDLLQNHLVSNLVDYVTGVEVGMDTNGRKNRTGDAMENIVQSYLE
                     AEGYILGENLFKEIEQNEIEEIFSVDLSAITNDGNTVKRFDFVIKNEQVLYLIEVNFY
                     SGSGSKLNETARSYKMIAEEIKAIPNVEFMWITDGQGWYKAKNNLRETFDILPFLYNI
                     NDLEHNILKNLK"
     gene            complement(15343..16113)
                     /locus_tag="VQ865_001298"
     CDS             complement(15343..16113)
                     /locus_tag="VQ865_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3135629.1"
                     /translation="MTKPYYNKNKMILVHSDTFKFLSKMKPESMDMIFADPPYFLSNG
                     GISNSGGQVVSVDKGDWDKISSFEEKHEFNRKWIRLAKEVLKPNGTVWISGSLHNIYS
                     VGMALEQEGFKILNNITWQKTNPAPNLSCRYFTHSTETILWARKNDKKARHYYNYDLM
                     KELNDGKQMKDVWTGSLTKKVEKWAGKHPTQKPEYLLERIILASTKEGDYILDPFVGS
                     GTTGVVAKRLGRRFIGIDAEKEYLKIARKRLEAENETN"
     gene            complement(16139..16993)
                     /locus_tag="VQ865_001299"
     CDS             complement(16139..16993)
                     /locus_tag="VQ865_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HET3135630.1"
                     /translation="MKIKEIKKVTLQPFTKWTGGKRQLLPVIRELMPKTYNRYFEPFV
                     GGGALFFDLAPKDAVINDFNAELINCYQQIKDNPQELIEILKVHQEYNSKEYYLDLRS
                     ADRDERIDMMSEVQRAARILYMLRVNFNGLYRVNSKNQFNVPYGRYKNPKIVDEELIS
                     AISVYINNNQLEIKVGDFEKAIVDVRTGDFVYFDPPYIPLSETSAFTSYTHEGFSFAD
                     QVRLRDAFKRLSDTGAYVMLSNSSSALVEELYKDFNIHYVEATRTNGAKSSSRGKISE
                     IIVTNYEK"
     gene            complement(17150..17554)
                     /locus_tag="VQ865_001300"
     CDS             complement(17150..17554)
                     /locus_tag="VQ865_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PaaI family thioesterase"
                     /protein_id="HET3135631.1"
                     /translation="MKDFHFDAISAFENYEIEKMRDGHVVVTTKVVNSSLNYYGNAHG
                     GYLFTLCDQISGLVVISLGLDGVTLQSSINYLKAGKLDDVLTIKGECVHQGRTTCVMD
                     VDITNQEGRNVCKATFTMFVTGQRSEERQVRI"
     gene            complement(17624..19105)
                     /locus_tag="VQ865_001301"
     CDS             complement(17624..19105)
                     /locus_tag="VQ865_001301"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HET3135632.1"
                     /translation="MTLVDKFVTHVISESSFEEMDRIYLTNRVLARVGEGVLEVETNL
                     DKLIDLKDQLVEEAVRLETIEDSQTAREILGTELMDLVTPCPSQVNRDFWEAYAYSPE
                     QAIEDFYQLSRKNDYIKLKAIAKNIAYRVPSDYGELEITINLSKPEKDPKEIAVAKLV
                     QASNYPQCQLCLENEGYHGRVNHPARSNHRIIRFEMVGQEWGFQYSPYAYFNEHCIFL
                     DGQHRPMAISRQSFERLLAIVEQFPGYFAGSNADLPIVGGSILTHDHYQGGRHVFPME
                     LAPLQKTFRFAGFEQVKAGIIKWPMSVLRLTSDSKEDLINLADKIFQEWRQYSDSSVQ
                     ILAETDGTPHHTITPIARKRDGQFELDLVLRDNQTSAEHPDGIYHPHKDVQHIKKENI
                     GLIEVMGLAILPPRLKEEVEQVASYLVGEAVTVADYHQEWADQLKSQHPDLTDKEKAL
                     AIVKDSVGAIFVRVLEDAGVYKQTEQGQTAFMRFVEQVGILLD"
     gene            complement(19124..20302)
                     /locus_tag="VQ865_001302"
     CDS             complement(19124..20302)
                     /locus_tag="VQ865_001302"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HET3135633.1"
                     /translation="MTQHLTAETLRKDFLAVFGQEADQTFFSPGRINLIGEHTDYNGG
                     HVFPAAISLGTYGAARKRDDQVLRFYSANFEDKGIIEVPLADLKFEKEHNWTNYPKGV
                     LHFLQEAGHVIDKGFDFYVYGNIPNGAGLSSSASLELLTGVVAEHLFDLKLERLDLVK
                     IGKQTENNFIGVNSGIMDQFAIGMGADQRAIYLDTNTLEYDLVPLDLKDNVVVIMNTN
                     KRRELADSKYNERRAECEKAVEELQVALDIQTLGELDEWAFDQYSYLIKDENRLKRAR
                     HAVLENQRTLKAQAALQAGDLETFGRLMNASHVSLEHDYEVTGLELDTLVHTAWAQEG
                     VLGARMTGAGFGGCAIALVQKDTVEVFKEAVGKHYEEVVGYAPSFYIAEVAGGTRVLD
                     "
     gene            20466..21473
                     /gene="galR"
                     /locus_tag="VQ865_001303"
     CDS             20466..21473
                     /gene="galR"
                     /locus_tag="VQ865_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000212522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator GalR"
                     /protein_id="HET3135634.1"
                     /translation="MATLKDIAQLASVSIATVSRVLNRDQSLSVTEETRHRILTVAEE
                     LGYTKHLKTGESHKPKQKIAIIQWVSEQGELDDLYYYQIRLGIEKRAQELDYDILRYF
                     NDHPFTLSEEVIGILCIGKFSRAQISAFEEYQKPLVFLDSDTLSLGHTCIITDFYTAM
                     KQVVDYFLSQGMDRIGILTGLEETTDQEEIIQDKRLENFRNYSQAKGIYHDELVFQGN
                     FTAQSGYDLMKEAIQSLGDQLPPAFFAASDSLAIGALRALQEAGISLPDRVSLISFND
                     TSLTKQVYPPLSSITVYTEEMGRAGMDILNKEVLHGRKIPSLTMLGTRLTLRESTLNQ
                     E"
     gene            complement(21519..22556)
                     /locus_tag="VQ865_001304"
     CDS             complement(21519..22556)
                     /locus_tag="VQ865_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HET3135635.1"
                     /translation="MKSAVYTKAGQVGLASIERPQIIEADDVIIRVVRACVCGSDLWR
                     YRNPETKAGHKNSGHEAIGIVEEAGEAITTVKPGDFVIVPFTHGCGECDACLAGFDGS
                     CDNHIGNNLGGDFQAEYIRFHYANWALVKIPGQPSDYTEGMLKSLLTLADVMPTGYHA
                     ARVANVQKGDKVVVIGDGAVGQCAVIAAKMRGASQIILMSRHEDRQKMAMESGATAVV
                     AERGQEGITKVREILGGGADAALECVGTEAAIEQALGVLHNGGRMGFVGVPHYNNRAL
                     GSTFMQNISVAGGAASATTYDKQFLLKAVLDGDINPGRVFTSSYKLEDIDQAYKDMDE
                     RKTIKSMIVIE"
     gene            complement(22557..22910)
                     /locus_tag="VQ865_001305"
     CDS             complement(22557..22910)
                     /locus_tag="VQ865_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HET3135636.1"
                     /translation="MNIKSASDLLGISADTIRYYERVGLVPPITRTATGIRDFQDQDI
                     EALEFIKCFRSAGVSVDSLVDYMSLYQKGDETREERLGILEEEKQKLEERLSQLQTAL
                     NRLNLKIKLYKEGKF"
     gene            complement(23154..24044)
                     /locus_tag="VQ865_001306"
     CDS             complement(23154..24044)
                     /locus_tag="VQ865_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HET3135637.1"
                     /translation="MKAKYAVWVAFFLNLTYAIVEFIAGGVFGSSAVLADSVHDLGDV
                     IAIGISAFLETISNREEDNQYTLGYKRFSLLGALVTAVILVTGSVLVILENVTKILHP
                     QPVNDEGILWLGIIAITINLLASLVVGKGKTKNESILSLHFLEDTLGWVAVILMAIVL
                     RFTDWYILDPLLSLVISFFILSKALSRFWSTLKIFLDAVPEGLDIKQVKSGLERLDNV
                     ASLNQLNLWTMDALEKNAIVHVCLKEMEHMETCKESIRIFLKDCGFQNITIEIDADLE
                     THQTHKRKVCDLERSYEHQH"
     gene            24177..24713
                     /locus_tag="VQ865_001307"
     CDS             24177..24713
                     /locus_tag="VQ865_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HET3135638.1"
                     /translation="MTNIDRRISKTKKAIYQAFIQLLNAKGYEATTVQDIIDLADVGR
                     STFYCHYESKELLLDQLCRYLFHHLFEREQAISTEDYLAHLFLHFHKNQDHITSLLFS
                     KNDYFLRQLHKELEHHVYSVLADNLKEAHPNMPTSYLQHLVVSNFIETLTWWLKKGQD
                     FTDQEVVQFYLDLLIPKN"
     gene            complement(24879..25685)
                     /locus_tag="VQ865_001308"
     CDS             complement(24879..25685)
                     /locus_tag="VQ865_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HET3135639.1"
                     /translation="MHTYLQKKIENIKTTLGEMSGGYRRMVAAMADLGFSGTMKAIWD
                     DLFAHRSFAQWIYLLVLGSFPLWLELVYEHRIVDWIGMICSLTGIICVIFVSEGRASN
                     YLFGLINSVIYLILALQKGFYGEVLTTLYFTVMQPIGLLVWIYQAQFKKEKQEFVARK
                     LDGKGWTKYLSISVLWWLAFGFIYQSIGANRPYRDSITDATNGVGQILMTAVYREQWI
                     FWAATNVFSIYLWWGESLQIQGKYLIYLINSLVGWYQWSKAAKQNTDLPN"
BASE COUNT         7803 a         5738 c         4612 g         7861 t
ORIGIN      
        1 gatttgtcct attattattt cattttacta tactctgtta attcatatga gtttaaaccg
       61 atttcatctt taacctcgag taaagcagtt tcaaatattt gtttaagagt ttttgattct
      121 ttacaattaa ccgacaaact ttctgataaa atatgtacaa cttctgagac tgaataacct
      181 atctcctctt tagaattata taaatctgta gctccaccaa taatccaaaa atactgattt
      241 tgtgaaccta caatatcctc attttctacg gaacttcctt gtatcgaaca aattttattt
      301 atctttacca taatacttca acccttttag tgtcaaaagt aaaccaattc ctgtcactgt
      361 taagaatagt tccataatct tgttcgaacc agtctttggt aatttttgtt ttacatctac
      421 tatttcttta gatttattaa tatgattttc agtttctctg ccatctccaa ctattttata
      481 gtttacttct tctgtcttat tatcttgttt attgtcgatc ttgtcattca tttgtctatt
      541 atctttactt gagttaaact ctccgttctt ctggttacta tcaattacat tatttgaatt
      601 agattgtttt tcctctttgt ttttttcttt ttcgttttta tcacttaaat tatttgttac
      661 aattttgtaa agcccattct ccgttacaat attgaaatta ccatcgctat cacgtataac
      721 aggttctttc ccatttgcat tagatttgat gactgatata tacttaccgg ataaattata
      781 aaattggtta tttaaaacgg ttattttacc ctttgaatcc tcaataacaa ttccttcttt
      841 accaccgaat atactattct ctgagactac taaattatca ctaactcgta ataattcaat
      901 atttggttgt tctgtttcct tagaattatt attaattaca ttttttgtta cagtaatatc
      961 tgatactttt cctaaatatt ctgcactatc ttttgcaact cgtatcgctt ttgttttagg
     1021 atcggcaata ttaaatatat tttcggcgat aaccacctgt ttatttaaat ctaataggtc
     1081 tttagtgttt ttatagctat aagcatttac taaagctgct ccgttttctc gataatgtac
     1141 actctctcct ttaactttct tatcaaagcg atttcctttg attaatacat cagtgaatcc
     1201 tgtaaaacgt acacctgcat acatcatgtt atcaaaatga ttatttaaaa ttttaatatt
     1261 agaggggttc tgtgtcgaca atgtttgata gtgtgtacca attgctgtta ctaattcccc
     1321 agatttatca cttttgccaa aataggaatt ttgaatagtc acattttcag attttttccc
     1381 atcatcattc aaggcataag gaaaaccttt tctagttaat ggttcaatct gaatgctctc
     1441 cttacttatg atttgcccat ccttcatcgt tttgggtaag gcttgcccaa gaaaacgaga
     1501 attatcaact aatacatttt tcgaacctgc aatttgaata gtatgccctt gataactatc
     1561 cttgaatgtt acatttttta tagttacgtt atttgaattc ccaatagcaa atgcacctga
     1621 agaatttata agtggtagat tttttgcttt agttccttct tcattcaaag caccgttcat
     1681 atcaatcgta ccaccagaat aactaatatc ttctgttggg ccccattcta cttgcgcacc
     1741 atcatccgta aataaacctg tcataaaaac aatggaaggg tgattcttaa tatttatacc
     1801 atttagaatt gtagctttct cattcaattc taagtgtgta tgacttttta aaaaaacaat
     1861 ttcttttact aaataagttc cttcaggaaa atatacattt cctccaccta gcccttgagc
     1921 tgcagcatct attgcatctt gaattgcttg tcgatcatca tgaatcccat cacctaccgc
     1981 accataatct tttacactta aagcagtatc ttcaaattct tttttgataa ttctgtcact
     2041 tataacatct tccttataac tcttattttc attagtagat gttactgtag attcaactgt
     2101 tctgttgtct aattgtgaat tggaacgaat agtaccatta gagctgatac tattaacact
     2161 taacgaatta tctaaaccat tagtggttga attagaggca atcatttcag cagaacgatt
     2221 ctgattaaca gttggtgaat tatctaaatc attagtaatt gcattagaag actcttttgt
     2281 agccatcggt gaagaactag taacaacttc atccgataaa ataccttggc ttcccaaaat
     2341 tgaaattgcc aatagtaccg agcaagtccc cacctttaat ttacgaatac tgaatacctc
     2401 attaggaaca aaatatttca tcagaacctc caattttttt actattttta acaattgatt
     2461 attacttttc ttaaaataga tagaatgaca ccgctgtcat tatctttatc atatattttc
     2521 caaattgaat tgtcaaggaa taacacaaga aaatattaaa atttatactc ttcggaaatc
     2581 tcttcaaact aggtcagtgc cgccttgccc taagtctagg ttactgactt ggtcagttct
     2641 atagtaaatt gaaactaaaa tagtacacct ctacttctaa aacattgtta gaaatcgatt
     2701 tgactgtccc gatcaatttg tcctattctt atttcatttt actatatcta caacctcaaa
     2761 gcagggtttt gagctatcta tggccaactt cctagtttgc tctttagcct tccattcaaa
     2821 agtgatgcta tctttcttag cttgaatata aaatatccca tttactatat ttaaatttat
     2881 tgatatgttg taaattataa ttgaaagaac aaataccttg tcatacaagc attcgccagg
     2941 gatatttaca tgaatatcgc tcatatggcg gattgaaact aaaacactac aatatatttc
     3001 ttaaatagac cttctataaa agctagattt aacctcgata aaaatagatg cagtgcttct
     3061 aaaatactgg aatagggcat ataggtaata gtagacaagt gttttataga ttgtctcgcg
     3121 ggagatctaa tgatgtatag caagcatcac taaacatata gaatatttgt gttattataa
     3181 tatcaatatg ctataaattc tatcatgcaa aagaatgact agaacatgaa agacaggcac
     3241 aaaactttga acaatattct gaaaacaaaa aaagacgcga gtttccacaa tctcactcat
     3301 ggaaactcac gtctttcaaa aaatagggtg aattaaaaac tagaacaaga cactagattt
     3361 tctaaatgat gtctagtaag gattctaaat gctacaccaa attgctcaca tcttatttca
     3421 aaccacggga ctcccacaag aaaggaaaat cctataaaaa ttctctctct gaggagagag
     3481 aggcctcaac tacaggtgta aactattatc aattgaaaac aacagttttt acactcaatt
     3541 agacttttta gggacaggat cactttcgct tgactgtagt ttgtcatttt tttgataaag
     3601 ttagcacttt ttcagaaact gttttgaaag tctcaatgat atagtctact tcttcatcgc
     3661 ttaatttagt atgaagaggg agggtaattt cattctcaaa gaaggcatag gccttaggat
     3721 agttcgtcat atcaaatcca agattcttat aggctgtcaa gagaggaagc ggtttgtatt
     3781 gaacattact tgcaattcct gctttagcca attcttggat gatgaggttg cgttcttcta
     3841 ggcttgctcc ttctacacgg gtgatgtaga ggtggcgtga agattcgaca gtttcagtct
     3901 tgtgtgccaa aggatggatg cgagaacctg caaaaccact atcatagcgg tccacaatat
     3961 ccttacggcg ttgcaacaaa cttggatagc ggtccaattg taccaaacca agtgaagcca
     4021 tgatatcggt catgttgcac ttataggctg gtgtaacgat atcgtattcc catgacccca
     4081 gttgcatctt ggcaagagca tccttagttt gcccgtgaag ggaaaggatt tggaattcct
     4141 tgtacatctc ttcgtcatca atcactggat tggctttcca agtcgcactt ccaccttctg
     4201 ccgttgtaaa gttcttaacg gcatggaatg agaaggaagt aaagtcagcg atagaaccag
     4261 aaggttgtcc tttataagta gatcccaaag cgtgggcact atcagagaca atgacaatac
     4321 ggttaaaggc cttttgccac ttgcttgaag cggtaaagaa gtcacgtttt ttctccacga
     4381 cttggaacaa acggtcataa tcgcaaacaa tccctgcgag ctctactggg ataatcacct
     4441 tagttttctc agtgatagct tgctcaagca ggtcatagtc catctcaaac gtatctgctt
     4501 ggatatccac catgacaggg gttgctccca cgtgcgtaat gacactacat gaagccgtat
     4561 aggttatggc tggaacgatg acttcatcac caggtcccac ttcaaaaacg cgtaaaatca
     4621 actccagagc ggctgtcgca gagttgagac aaacagtctt aggtgtctgt gtgtaaagag
     4681 acaagcggcg ctccagttct tttgttttag gacctgttgt gatccaacca gaacgcaggg
     4741 tatccgctac ttcagcaatt tctgcttctg tgatatcagg cggtgaaaat ggaatattgt
     4801 aatttggcat tgatttgctc cttttatctg tactcattct cttatgacta ctttatttta
     4861 gtaccttaaa cacggtttga aacatgattt tgatgtcccc aaagaaacta aactctcgga
     4921 gataggcgag gttatagcgc atcttttcag gaagaacatg ctccacatag gcctgatcaa
     4981 ctgacagacc tttctctgtc atttgactga tgatggtgtc ctcatccttg tagttgatgc
     5041 tggctggaga ggtaattcct gcttgcaaga gcaaggttgc catcatttca gtgctatact
     5101 gctctgtata acgtggcact tcaggtcgtg taccgacaaa ggacatctca cctttaagga
     5161 cattgaccaa ctgaggcagt tcgtccaaac ggacacgtcg gatgaaattt ccaaccttgg
     5221 taatacggct atcgttagca gaagtcacca gatttccttt tttatccgca tccgtcacca
     5281 tggtacggaa cttccaaatc ttgaaccgac ggttgtactg ggtcacacgc tcttgcttgt
     5341 aaatcactgg ccccttgcta tccaacttga tccaaatgct caagatgaga aagatgggag
     5401 aggtcagaac cagtaagacc aaggccaaaa cccagtccaa gcaacgcttg aaaatcagcg
     5461 aacccttcct tttagagaca agctggtagt aagactcaac ctcgcttgat ttcatttcca
     5521 caggcaagtc ttcccatttc agcatgctgt tctcctttgt ttttattata ctatttgtca
     5581 acactttttg tcaacacttt tcattatacc acaaaatgga aaaggcggtg aaaaaaatct
     5641 gtaatttgaa ggatttcctt ctagtactca atgaaaatca aagtacagct ttgagattgc
     5701 agataaagct gacatggttt aaagagattt tcaaagagta taggccatgg cccctgcctg
     5761 caaactatac atcttgtgat aggttcctcc cagagccaag agttcctcat gggttccact
     5821 ctcgataatg cgtcccttat ccaagacata gatgcagttg gcgtcttgaa tagtagaaag
     5881 gcggtgagct atagcaatag ttgttcggcc ctgtctcatc ttcgccagag aagcttgaac
     5941 caagctttct gtttcagagt caatattggc tgtcgcttca tccaaaatca ggattttagg
     6001 ctggctggcg actgttctag caaaggcaag aagctggcgt tgcccagtag agaagctcga
     6061 accacgctcg gaaacagggg agtcgtaccc ctgaggaagt tcttgaataa aggaatctgc
     6121 atccacaaag gctgccgcag cctgaacctg ctcatcactg atttcttggt acatggcgat
     6181 attggactta atagttccat gatagaggaa gggttcctgc aagaccaaac cgatgttttt
     6241 tctcagctct tcttgactga aatccctgat atccacatca tccaagagaa ctctccctga
     6301 ctggaattca taaaagcgca tgaggacatt gataatagac gatttccctg aacctgtatg
     6361 acctacaaag gcaatggttt cacccttatt aacagagaaa gaaatgtcat ccagaatcgg
     6421 atgtttaccg tcatatgaga aacacacatg ttcaaagcgg atattgcctt cttggacttt
     6481 ggcttgccca ttttcttgaa gaggttcata ggtcctctcg tctaccaggg caaagacacg
     6541 acctgcagaa accatagacg tttgcagtgt tgaaaagttt tgcgtcacct caatcaaagg
     6601 gtcaaagagg cggttgatgt actggataaa agcatacatg gtcccggccg ttatcccgat
     6661 agaaagacca cgatagccaa aataggccat caagacagca taacctagaa gtttcaacaa
     6721 actcatggca ggtctcaaaa agagggcatc caaggctaca gaacggttgg catagaccaa
     6781 gtgctcttgg ttgatttcat caaattctgc ctgcaggcgc ttctcttgat taaaggcctg
     6841 gattattctg attccctcga tgttttcagc cagcttgcta ttgatatctg acaagagact
     6901 tctggttttc tcaatgattt tcactgattt tttccgatag agattgacca aaaggaaaat
     6961 caaggggaga aagagcaaga ctaatgctgt caaacgaaaa tccaatacca acatggtata
     7021 aagggttgtc agaaagatga aaactgctga gataaagcta gataaaatcc cagaaaacat
     7081 atcactaatc gtctcggtat cgttggtcaa acgagaaacg atagaacctg ctggcgtctt
     7141 gtcaaagtaa gacatgccca gtttctccat attggcaaag gcatcccgac gaatatccct
     7201 aacaatactg taagacacgc gcgcaaagag aagattgccg acatactgaa ctacagtttg
     7261 taggatgtag agaccatagt agaccagcaa aacggtaacg gctagttggt taagattgct
     7321 gagatactgg tcgataaagt gggaagccac gaggggtatg acacttttaa tgaccgtcgt
     7381 cgctaggaga aaactgagtg ccaaaaaggt caggagtcta taaggcttga gataagacat
     7441 caagcgcttc aatacagccc attgttcttg tttattctgc atcttcttct cctttcattt
     7501 ctaactgctg agactggtag gtttgggcat accagccatc catcgctagc aagtcttcgt
     7561 gcctgcctcg ttcgataatt tgaccatttt gtagaactaa aataaaatct gcatggacaa
     7621 cagcactgag gcgatgggca gttataatgg ttgtcttgtc ctttcgcgtc tccttgaggt
     7681 tgtcgataat cgcatactct gtcttggcat ctacggcgga taaggaatca tccaaaatca
     7741 agatatcagg gtttaaaatc atagcccgac tcatagccaa ccgttgcttt tgaccaccag
     7801 aaagactgac tcctttttca ccaatcagcg tatcaaatcc ttgaggcatg tctacaatat
     7861 cttggtaaac tcgggctagc ttagtagctt cctcaacctc tgaaaggggc aagttaggat
     7921 tgccaaagcg gatattgtct aggattgaag tcgcaaagag aaactggtcc tgaggaacat
     7981 agcccatgag actgcgaagt tctgtcaaac gatagtcccg aatatcgtga ccgtttagat
     8041 aaatggcacc cttatccaca tcgtattcac gcaagaggag cttgattaag gacgttttcc
     8101 cagagcctgt ctgcccaacc aagcccagtg tttgcccttt tgccaaacta aagtgaatat
     8161 ccgtcagtgt ttcctcattt tcaaaagcaa agctgtcaat ggcatactcc aaacgcccat
     8221 tttcaatacc atccagagga aactcagggt cttgtacagg agattcctga gacaaaagat
     8281 tttcaatccg ctggtaagaa accttccctc gctgagtagt attaaagagg aagccgatgg
     8341 ccataagagg ccagaccagc atatccaaat agctgataaa ggtgactaga ttaccaactg
     8401 taatctgccc ttcctgaacc atcaaggagc caaccaaaag cgttaaaaca taggacgaac
     8461 caacaaacaa gagaaccata gggtcaaaga gactatcata tttcatggtt tgcaggttct
     8521 tttggaaggt taattcattg actgcctgaa aagacttcaa ctcgtctgcc tgataaccga
     8581 aagacttggt cactttgata cctgatacgg actcctgtac cttgttattg agttcagaaa
     8641 aagcagcttg ggattcgcca aaggccttat gagtctttct ccctaggcga ctagtcgcat
     8701 aggccatgaa aggtaggggg agaatggcaa caagagtcat ctgccatgag atgctaaaga
     8761 gcatggtcaa caaagtcacc agagccgtga tagaggcatc caccgcagac atgacaccgc
     8821 cacctgctaa acgagtcaag gcattgatat cattggttgc gtgtgccatc agatcacccg
     8881 tccgataggt ttgataaaag gctggcgaca tttttgtgaa atgcttaaac aagcgagacc
     8941 gcatgatctg tcccaagcaa taagaggtcc caaggatata catacgccac acatagcgca
     9001 aatagtacat accaaaggct gcaagtagca agtaaaatag gctaagaagg aggtcctgct
     9061 gggttaattg ccccgatgtg atggcatcaa tgactcgccc cataaccata ggaggaatga
     9121 gattgagaac ggaaaccaag accagggcca caatcccgac tagataacgg tgtttttcta
     9181 acttgaaaaa ccaccagagt ttttgaataa tggacataaa atccctttct gattgcaaat
     9241 ggaaacctga ggccaatact caatgaaaat caaagagcaa actaggaaac tagccgcagg
     9301 ctgctcaaag cactgctttg aggttgtaga tagaactgac gaagtcagta acctacatac
     9361 ggcaaggcga cgttgacgcg gtttgaagag attttcgaag agtacaagac cccaggtttt
     9421 tcttattcat aagttacgac tgtaacagca cccttgtcat attcagcaat aaagatattg
     9481 gctacattgt catgcccttg tttgctgagg ttatcaagca accactcttc gctacgacca
     9541 atcgattcca agacgtctac ttgaatcaca ccgtcagtca caactggata cttaggattt
     9601 tcatctccca tttgcacaac gatgagttgc ccattttgct cttgcacagc tcgtttgact
     9661 tgcttcatct ggaaaatccc ttggctacga agtttgaggg ctacatccga tgcagacaaa
     9721 ccaactgaac gacaggctta tgggtcaata ttcccatttt tgataaggag agttggctta
     9781 ccatcaatca aacgtttcac aaagtgaaca ttgttgttga gctatttgag agtcaagatc
     9841 agtttgatta aaatttcgat ataattaagt gtcatttgtt cacatccacc agttcaattg
     9901 cgtctgtctt atacaattcg actttctcta acaggtactt gtctggctca cttccgttta
     9961 gggcacgata atagcgatct cccaccttga taagtgcgcc atctgtgttt gtggaagtat
    10021 taacatggac ttctgacttg tctactccca aatctttgga aacaacctcg atgaaatgaa
    10081 gtgaagtttg aaatttattg ttagaaactt gattgttttg ataagtcgtg atgctgacca
    10141 aaagcatagc taaataaggc cagagctgaa atcatgacca actcacgaaa tttggttcct
    10201 tttttatcat ggtatgcctt gaaagcaaaa aaaactgtca cagctaatag aacaatccca
    10261 aagccaacca tgataccatt ttgctgaccg atttggctga gtacatagtc ataagagtag
    10321 aatttcatgt attttcactc cctttcataa aatcattctt aattataaac gaaagagagt
    10381 aatttttcaa accatacgtt ggggaaatag ctcttttttt ggtataataa aatctataat
    10441 ctgaatgaaa aggtaacttt atgaaactta tctcatggaa tattgattcc ctaaacgctg
    10501 ccctaactag tgactcagct cgtgccaaat tgtcccaaga agtcctacaa accttggtcg
    10561 ctaaaaatgc tgatattatt gctatccaag aaaccaagct ttctgccaaa ggacctacaa
    10621 agaaacacgt ggaaatttta gaagaactct tcccaggcta cgaaaacacg tggcgttctt
    10681 cccaagagcc tgcccgtaaa ggctatgctg gaaccatgtt tctttataag aaagaactta
    10741 cacctactat cagcttccca gaaatcggtg ccccttctac catggacttg gaaggtcgta
    10801 tcatcactct agaatttgat gcatttttcg taacccaagt ttacactcca aacgctggtg
    10861 acggtctcaa acgcttggaa gaacgccaag tctgggatgc caaatatgct gagtatttgg
    10921 ctgaactaga caaagaaaaa ccagtccttg cgaccggtga ctacaacgta gcccacaatg
    10981 aaatcgacct tgcaaatcct gctagcaacc gccgttcacc tggatttact gacgaggaac
    11041 gtgctggatt taccaacctt ttggcaactg gatttacaga caccttccgc catgttcatg
    11101 gcgatgttcc tgaacgctac acttggtggg cacaacgcag caaaacttct aaaatcaaca
    11161 atacaggctg gagaatcgac tactggctca caagtaaccg tatcgctgac aaggtcacta
    11221 aatctgatat gattgactca ggtgctcgcc aagaccatac accgattgtc ttggaaattg
    11281 atttgtaagg attttctata tggactacaa tgcggtcatt cccgagttgc ttgtatcgaa
    11341 tatcgaacag tcccggtcct tctactgtgg tttactgggt tttaggattg aataccaacg
    11401 tccagaagaa aactttctct ttctcttgaa gagtgtcaac taatgttaga ggagggaaca
    11461 aaggatcaac tagctgaact gacctatcca tttggtcgtg gagtcaatct ctcctttggc
    11521 ataaaggatg tttcaaaact ctatcaaaga gtgatgaagg caaactatcc tatttatcgt
    11581 cccttgacca aaagaaagtt tcgtgtcagt gatccctata tctatcctca tgaatttgca
    11641 gttttggatc cagatggcta ttttttaaga tttagcgagt agaataataa aaattgggaa
    11701 aagtctttaa agttagaaaa aggcatattg tcaggtgttt aaaaacttga tagtatgcct
    11761 tttatgatgg aaaaatcttc taatactctt cgaaaatctc ttcaagccac atcaacgtca
    11821 ccttaccata ggtatatgat actgactctg tcaattctat ccacaacctc aaaacagtgt
    11881 tttgaggttg tggatagctt cctagtttgc tctttgattt tcatttagta taaatgttag
    11941 cttacaacgg agtttttgtt caccccctct tctgtttgtt cgttttttaa atcaaaacac
    12001 taacaaaata gttgatttat aaagttattt agtgtaaaat aaaaacattg gctcaagcct
    12061 atttaaaatt gaatatcgtt ttacttgttt atgtcgtgaa ttggcacgac gtttctacaa
    12121 ggtgccggaa cacctaacaa taagtaagtc agcagtgaga tatggccgtt tttgccatgc
    12181 ctatttgggg gacttactta gagattaagt aggtcttttt tgaatatttt taatatttcc
    12241 cttaattagt gcggacggga ggtgaaatta tcctgtgaat aatttcagga atccagggaa
    12301 tttcatccct aatttttgag cccctagctc tttcatttct aggcttaggc taaaatagtt
    12361 ccccgaacta ttttactctc aaaaatcccg tcatagacaa taacaagatt attgtctatg
    12421 ataccactac aacgggaaat atttgataag actcgcttcg ctcgtaatag ttttatcaaa
    12481 tatatagtat tagcaaaagg gatcactata gaaatattta aacaacaagt aaattaactt
    12541 ttagacttta ggaggtctta tgaaattatt agaagagcgc atcctcaagg atgggcatat
    12601 cttgggtgat aacatcctca aggtagattc ctttttaacc caccaagttg actttagctt
    12661 gatgcgagag attggtaggg tttttgcgga aaaatttgct gctactggca ttaccaaggt
    12721 cgtaaccatt gaagcgtcgg gtattgcccc agccgttttt acagctgaag ccttaaacgt
    12781 tcccatgatt ttcgccaaaa aagctaagaa catcaccatg aacgaaggca tcttaactgc
    12841 tcaagtctac tcctttacca aacaggtgac cagcaccgtt tctatcgctg gaaaattcct
    12901 ctcaccagag gacaaggttt tgattatcga cgatttcctt gctaatggcc aagctgctaa
    12961 aggcttgatt caaatcatcg aacaggccgg tgccacagtc caagctatcg gtatcgtgat
    13021 tgagaaatcc ttccaagatg gccgtgattt gcttgaaaaa gcaggctacc ctgtcctatc
    13081 acttgctcgt ttggatcgtt ttgaaaatgg tcaggtcgta tttaaggagg cagatctcta
    13141 atgcaaactc aagaaaaaca ctcgcaagca gccgttcttg gcttgcagca cttactagcc
    13201 atgtactcag gatctatcct ggttcccatc atgattgcga cagcccttgg ctattcagct
    13261 gagcagttga cctacctgat ttctacagat atcttcatgt gtggggtggc aaccttcctc
    13321 caactccaac tcaacaaata ctttgggatt ggactcccag tcgttcttgg agttgcattc
    13381 cagtcggtcg ctcccttgat tatgattggg caaagccatg gtagtggcgc tatgtttggt
    13441 gcccttatcg catctgggat ttacgtggtt cttgtttcag gcatcttctc aaaagtagcc
    13501 aatctcttcc catctatcgt aacaggatct gttattacca cgattggttt aaccttgatc
    13561 cctgtcgcta ttggaaatat gggaaataac gttccagagc caactggtca aagtctcttg
    13621 cttgcagcta ttactgttct gattatcctc ttgatcaaca tctttaccaa aggatttatc
    13681 aagtctatct ctattttgat tggtctggtt gttggaactg ccattgctgc tactatgggc
    13741 ttggtggact tctctcctgt tgcggtagct ccacttgtcc atgtcccaac tccactctac
    13801 tttgggatgc caacctttga aatctcatct attgtcatga tgtgtattat cgcaacggtg
    13861 tctatggttg agtcaactgg tgtttatcta gccttgtctg atatcacaaa agatccaatc
    13921 gacagcacgc gccttcgcaa cggttaccgc gcagaaggtt tggccgtact tctcggagga
    13981 atctttaaca ccttccctta caccggattt tcacaaaacg ttggtttggt taaattgtca
    14041 ggcatcaaaa aacgcctgcc aatctactac gcagctggtt tcctggttct ccttggactg
    14101 cttcctaagt ttggtgccct tgcccaaatc attccaagct ccgtcctcgg cggtgccatg
    14161 ctggtgatgt ttggttttgt atctattcaa gggatgcaaa tcctcgcccg agttgacttt
    14221 gctaacaatg aacacaactt ccttatcgca gctgtttcaa tcgctgcagg tgtcggtctc
    14281 aacaacagta atctctttgt cagcatgccg acagccttcc aaatgttctt ctcaaacgga
    14341 atcgtcgtag ccagcctact cgccattgtc ctcaatgccg tattaaatca taaaaagaaa
    14401 taagaaaaag aggtgcgagc ctcttttttg tttatcacaa attgattata aatacaatca
    14461 atcccaattc ccatctaatt gaattggacc tatttcaaat tctttaaaat attatgttcc
    14521 aaatcgttaa tattatataa gaatggtaaa atatcaaatg tttctcgtaa attattctta
    14581 gccttatacc aaccttgtcc atcagtaatc cacataaact caacattagg aatagcttta
    14641 atttcttcag caatcatttt gtaagatcta gccgtctcat ttaattttga accacttcct
    14701 gaataaaaat taacctcaat cagataaagc acttgttcat tttttatgac aaaatcaaaa
    14761 cgtttcacag tattcccatc attcgtaata gcagataaat cgacagaaaa aatttcctct
    14821 atttcatttt gttcaatctc tttaaataaa ttctctccta aaatataccc ttcagcttca
    14881 agatagcttt gaacaatatt ttccatcgca tctccagtcc gatttttgcg cccattagta
    14941 tccataccaa cctcaacacc tgtaacgtag tcaactaaat ttgatactaa atgattttgc
    15001 aataaatcaa atatacctga tttttccaaa aacatagtat attcttcaat actatagttt
    15061 cgtttactaa aatcaaaata gaaatctttt atcggatcct taacaataat cgtatctctc
    15121 aaacgtttag caataagtag aggcacaact ttcaaaattt ctggataatt ttgatataag
    15181 tctaaaaaat cctcttgtat atttttacta ccaataagac tattcataat atttagagca
    15241 acttttatac tagatacatt tttataaacc ttaggaaaat ctgtataata agtccagtca
    15301 gctactgtgt cggtcatcgt tgacaaccac tcatcaaaat ttctagtttg tttcattttc
    15361 tgcctccaac ctcttccttg caatttttaa atattctttt tcagcatcga tacctataaa
    15421 tcttctacct aaccgcttcg caacaacacc cgtagtgcca ctaccaacaa atgggtctag
    15481 aatatagtca ccctctttag tagaggctaa aataatgcgt tctaacaaat actctggttt
    15541 ttgagttgga tgtttcccag cccatttttc aactttcttt gttaaagaac cggtccagac
    15601 atctttcatt tgttttccat cattcaattc tttcattaaa tcataattgt agtaatgacg
    15661 agctttttta tcattttttc tggcccataa aatggtttca gtagaatggg taaaataacg
    15721 acaagataaa ttgggggcag ggtttgtttt ctgccaagta atattattca gaattttaaa
    15781 accttcttgt tctaatgcca ttccaactga gtatatgttg tgcaaactac ctgaaatcca
    15841 taccgtccca ttaggcttca gaacttcttt tgctaggcga atccatttac gattaaactc
    15901 atgtttttct tcgaatgaag aaattttatc ccaatctcct ttatcaacag aaacaacttg
    15961 tcccccagaa ttagatattc caccattact taaaaaataa ggtggatcag caaaaatcat
    16021 atccatactt tctggtttca tttttgataa gaacttgaac gtatctgaat gaacaagaat
    16081 catcttattt ttattgtagt atggttttgt cataagaaca cctccatact tatattcgtt
    16141 atttttcata atttgtgact ataatttcag aaatttttcc tcgacttgaa gattttgctc
    16201 cattagttcg ggtagcttca acataatgta tattaaaatc cttatacaac tcctctacta
    16261 aagcactaga agaatttgat aacataacat aagctcctgt atcactcaat ctcttaaagg
    16321 catctcttaa tcttacttga tctgcaaaag agaatccctc atgagtataa gacgtaaatg
    16381 cactcgtctc agacaatgga atatatggag ggtcaaaata cacaaaatct cctgttcgaa
    16441 catctacaat tgccttttca aaatctccca ctttaatttc tagttgattg ttatttatat
    16501 aaactgaaat agcagatatc aattcctcat caacaatttt aggattctta taacgtccat
    16561 atggaacatt aaattgattc ttagaattca cacgatatag accattaaag ttcactctca
    16621 acatatatag aatacgtgca gctctttgta cttcggacat catatctatt ctttcatcac
    16681 gatctgcaga acgtaaatct aaataatatt cttttgaatt atattcctga tgaactttca
    16741 aaatttcaat caattcttga ggattgtcct taatttgttg atagcaattt attagttcag
    16801 cgttaaaatc attaataact gcatctttag gagccaaatc aaaaaataaa gctccacctc
    16861 caacaaaagg ttcgaaatac ctgttatagg ttttaggcat taattctcta ataacaggca
    16921 ataattgtct tttaccacct gtccatttcg tgaacggttg taaagtaact ttctttattt
    16981 cttttatctt catgctttta attataccat agaaattaaa acacaactct tgtattttct
    17041 accacattac taaattttct attttagaat taaatcatat caatatcaaa aaatgagtaa
    17101 ggcaaatctt ataaattcca aaattcacct cactctatta aattactctt tatatcctta
    17161 cctgtctttc ttctgaccgc tggcctgtga caaacatggt aaaggttgct ttacagacat
    17221 ttctgccctc ttgattggtg atatccacat ccatcacaca ggttgtacga ccttgatgga
    17281 cacattctcc tttaatggtc aatacatcgt cgagttttcc tgccttaagg tagttgatag
    17341 aggattggag tgtcacccca tcaagtccca gcgagataac caccaaacca ctgatttggt
    17401 cacatagcgt gaatagatag ccaccatggg cattgccata gtagttgagc gacgagttca
    17461 ctactttggt cgtcaccaca acgtgaccat ctctcatttt ttcaatttcg taattttcaa
    17521 aggcagatat agcgtcaaaa tgaaagtctt tcatcgtttc ctcctgatat ttcaaacgac
    17581 actatgatac tactttttat aggactgtgc aaggagaaag ctcctagtct agtaaaattc
    17641 cgacctgttc cacaaagcgc ataaaggctg tctgaccttg ttctgtctgc ttgtagactc
    17701 ctgcatcctc aagtacacgc acaaagatag cacccacaga gtccttgacg attgcaaggg
    17761 ctttttcttt atccgttagg tctggatgtt gggatttgag ttggtctgcc cactcctgat
    17821 gataatcggc aactgtaaca gcttctccta caagatagct agcgacttgc tccacttctt
    17881 ctttcagacg tggtggcaag attgccaagc ccatgacctc aatcaagccg atattttcct
    17941 tcttgatatg ttggacatcc ttgtggggat gatagatgcc atcaggatgc tctgctgaag
    18001 tctgattgtc tcgcaagacc aagtccaact caaactgtcc atcacgctta cgcgctattg
    18061 gtgtgatggt gtgatgcggt gtcccgtctg tctctgctaa aatctgcaca ctagaatctg
    18121 aatactgacg ccattcctgg aaaatcttat cagctaagtt aatcaaatcc tctttggaat
    18181 ccgaagtcaa gcgtaggaca gacattggcc acttgataat tccagccttg acctgctcaa
    18241 aaccagcaaa tcggaaggtc ttttgcaagg gagccaattc cataggaaat acgtgacggc
    18301 ctccctgata atgatcatga gttagaatag agccccccac aatcggcagg tcggcattag
    18361 atccagcaaa atatcctgga aactgctcta cgatagccaa cagacgttca aaactctgac
    18421 gactaatggc catgggacga tgctggccat ctaaaaagat acaatgctca ttaaagtaag
    18481 catagggcga atactggaac ccccattcct gaccaaccat ttcaaaacgg ataatccggt
    18541 ggttgctgcg agctgggtgg ttgacccgac catggtaacc ctcattctct aaacaaagtt
    18601 gacactgagg ataattacta gcttgcacca acttggctac cgcaatctct ttcggatcct
    18661 tttcaggctt agagagattg atggtaattt caagttctcc ataatcagat ggaacacgat
    18721 aagcgatatt tttagcaatg gccttgagtt tgatgtagtc atttttccga ctgagttgat
    18781 aaaaatcctc tatcgcttgc tcaggagagt aggcataggc ttcccagaag tcacgattga
    18841 cctgactcgg acaaggagtc accaagtcca tcagttcagt accaaggatt tcacgcgcag
    18901 tctgactatc ctcaatcgtc tctaatcgaa cggcttcctc aactagctgg tccttgaggt
    18961 caatcaattt atccagattg gtctcaactt ccaaaacacc ttctcccact cgtgccaaaa
    19021 cacgattggt caggtagatt cgatccattt cctcaaatga actttcagaa atgacatgtg
    19081 ttacaaattt atctactaag gtcactatag agcctccttt tgactagtca aggacgcgag
    19141 tgccacctgc aacttcagcg atatagaagc ttggagcgta tccaactact tcctcgtagt
    19201 gtttgcctac agcttcctta aagacctcaa cagtatcttt ttgaaccaag gcaatggcac
    19261 agccaccaaa accagcccct gtcatacgag caccgagaac tccttcttgt gcccaagctg
    19321 tgtgaacaag ggtatctaat tccaaaccag ttacttcata atcatgctcc agagaaacgt
    19381 gtgacgcatt catcaaacga ccaaatgttt ccaaatcacc tgcttgaagg gctgcttgag
    19441 ctttaagggt gcgttggttt tcaagcacag catggcgagc acgtttcaaa cgattttcat
    19501 ctttaatcag atagctatat tggtcaaagg cccactcgtc caattcaccc aaggtctgaa
    19561 tatccaaggc aacttgcaac tcttccactg ctttttcaca ctcagcacga cgttcattgt
    19621 atttagagtc cgccaattca cggcgtttgt tggtgttcat gataacaacg acattgtcct
    19681 tcaaatcaag tggcaccaaa tcatactcta aggtgttggt atcaaggtaa atagcacgtt
    19741 gatcagcccc cataccaata gcaaactggt ccatgatacc agagttgact ccgataaagt
    19801 tgttttctgt ttgttttccg attttaacca aatcgagacg ctctaatttt aaatcaaaga
    19861 gatgctctgc cacgactcct gtcaagagct ccaaggatgc tgaagaagac aaaccagcac
    19921 catttggtat attcccataa acataaaaat caaaaccttt gtcaatcacg tgcccagctt
    19981 cttgcaagaa atgaaggaca ccttttggat aattggtcca gttgtgctct ttttcaaact
    20041 tgaggtcagc gagaggcact tcgataatgc ccttgtcctc aaagttagct gagtagaaac
    20101 gcaaaacttg gtcgtcacgc ttacgagctg caccgtaagt tcccaaggaa atagcagcag
    20161 gaaaaacgtg cccaccgttg tagtctgtgt gttcaccaat caaattgata cgacctggtg
    20221 aaaagaaagt ttggtctgct tcttgaccaa aaacagcaag aaagtctttg cgaagagttt
    20281 cagcagtaag atgttgtgtc atatgatttc tcctttgact gtccgttaag ccaccttaac
    20341 gtgtaatcgt tttcttctat tgtatccaag ggatttccca aggtcaatcc tttttactaa
    20401 aattttacta aaatatcagt aaaaagcaga aaaatatgat atactaacct aatcaaggag
    20461 gatttatggc taccttaaaa gacattgcac agctagcctc tgtctctatc gcgaccgtat
    20521 cccgtgtcct caaccgcgac cagagcctat ctgttacaga agaaaccaga caccgtattt
    20581 taaccgttgc tgaagagctg ggctacacca agcacctcaa gacaggcgag tcccataaac
    20641 ccaagcaaaa gattgccatt atccaatggg tcagcgaaca aggggagctg gacgacctct
    20701 actactacca gattcgccta ggaatagaaa aaagagccca agagttggac tatgatatct
    20761 tgcgctattt taatgaccat ccttttacct taagcgagga agtgattggg attctctgca
    20821 ttggaaaatt tagccgagct cagatttctg cctttgaaga ataccaaaaa cccctggtct
    20881 ttctagacag tgatacactt tccctgggac atacctgtat tatcacggat ttttacactg
    20941 ctatgaaaca ggttgtcgat tatttcctca gccaaggaat ggaccgtatc gggattctaa
    21001 caggccttga agaaacgact gaccaagaag aaatcattca ggataagcgg ctggaaaatt
    21061 tcagaaacta cagtcaagca aaaggaatct atcatgatga actggtcttt caaggaaact
    21121 ttactgccca gtctggctat gacttgatga aggaagccat tcagagcttg ggagaccaac
    21181 tcccaccagc atttttcgca gccagcgata gtttagccat cggtgccctt cgtgcgctcc
    21241 aagaagctgg aatcagccta ccagaccgtg tcagcctcat ttcctttaac gacaccagcc
    21301 tgaccaagca ggtttatcct cccctctcca gcatcacagt ttatactgaa gaaatggggc
    21361 gagcaggtat ggatattctt aacaaggaag tcctccacgg tcgcaaaatt cctagcctga
    21421 ccatgctggg aaccagactg acattaagag aaagtaccct aaatcaagaa taggataaca
    21481 taaaaaacga atagagttct aaaactccta ttcgtttttt attcgattac aatcatagac
    21541 ttaattgtct tacgttcatc catatcttta taggcttggt cgatatcttc cagtttataa
    21601 cttgaagtaa agacgcgacc tggattgata tcaccatcaa ggacggcttt tagtaaaaat
    21661 tgcttatcgt atgttgtagc agaagctgcc ccacctgcta cagagatatt ttgcataaat
    21721 gtcgaaccaa gagcacgatt attatagtgt gggactccta caaagcccat acgccctcca
    21781 ttatgaagaa cacctagcgc ctgttctata gcagcctccg taccaacaca ttcaagtgct
    21841 gcatctgctc ctccaccgag gatttcacgc accttggtaa ttccttcttg accacgttct
    21901 gcaacaacag ctgtcgcacc tgactccata gccatctttt gacggtcttc atgacggctc
    21961 ataaggataa tttgtgatgc tccacgcatc ttagccgcga tgacagcaca ttgaccaaca
    22021 gccccatcac cgataacaac aaccttgtcc cctttttgaa catttgcaac acgcgccgca
    22081 tgatagcctg tcggcatgac atctgcaaga gtcaaaaggg acttgagcat cccttctgta
    22141 tagtcagaag gttgaccagg gattttaacc agcgcccagt ttgcatagtg gaagcgaata
    22201 tattctgcct gaaaatcacc ccccaaatta ttgccaatat gattgtcgca agaaccgtca
    22261 aatccagcaa gacaggcatc acactcacca catccatgtg taaaagggac aatcacaaaa
    22321 tcacctggtt tcaccgtcgt aatggcttcc ccagcttctt caacaatccc aatcgcttcg
    22381 tgtccactat ttttgtgtcc agctttcgtt tctggattac ggtacctcca taaatctgaa
    22441 ccacaaacgc acgcacgaac cacacgaata atcacatcat ccgcttctat tatttgcgga
    22501 cgttcaatgc tagcaagtcc aacctgacct gcctttgtat atactgctga tttcatttaa
    22561 aattttcctt ccttataaag tttaattttg agatttaaac gatttaaagc tgtctgtagc
    22621 tgagacaagc gctcctctaa tttttgcttt tcctcttcta aaataccaag cctctcctct
    22681 ctcgtttcat ctcccttttg gtagagcgac atatagtcaa ctaaactatc tacagagaca
    22741 cccgccgaac gaaaacactt aataaattcc agcgcttcga tatcctgatc ttgaaaatca
    22801 cgaatcccag tagcagtacg agtaatcggt ggcacaagac caacccgttc ataataccga
    22861 atcgtatccg ctgaaattcc caacaaatca ctggcagatt taatattcac acgctaacct
    22921 cctctcattt cattcactga attcacgcta ttctaactca cttatcttat tatataactt
    22981 tgagttgact ccaagtcaag cattttgtat ctaatcgaaa aatttttatc attaacaatc
    23041 atatatctgg agtttataca atgctcttct cttaccaatt tttgaaatat ttaaataata
    23101 aagaaattac tctattccaa ataagatagt acccaagtat ttttcacttt tttctaatgt
    23161 tgatgctcat aactccgttc caagtcacac acctttcgct tatgggtttg gtgagtttct
    23221 aggtcagcat caatttcaat ggtaatattt tgaaaaccac aatcttttag gaaaattcga
    23281 atagactctt tacaagtttc catatgttcc atttctttta gacaaacatg gacaatggca
    23341 tttttttcca aagcatccat agtccagaga ttaagctgat taaggctggc cacattgtcc
    23401 aatcgttcca ggccactctt tacttgcttg atatcaagac cttctggcac agcatccaag
    23461 aaaatcttga gtgtagacca aaaacgtgaa agggcttttg aaagaataaa gaaagaaatg
    23521 acaagggaca aaagaggatc taggatatac cagtccgtaa atcgaagaac aatcgccatc
    23581 aggataacag ctacccaccc tagcgtatct tccagaaaat gcagactcag aatagactca
    23641 ttctttgtct ttcccttacc aaccaccaga ctcgctaaca gattgatagt aatcgcaata
    23701 attcctaacc agagaatccc ctcatcattg actggttgcg gatgcaaaat cttcgtgaca
    23761 ttttccaaaa tgactagaac agagcctgtt acgagaatca cagctgttac caaggctcct
    23821 agcaggctaa accgcttata gcccaaggtg tactgattgt cttcttcacg attggagatt
    23881 gtttctagaa aagctgatat tccaattgca atcacatctc ccaagtcatg cacagagtca
    23941 gcaagaacag cgctagaacc aaatactcca cctgcaataa actcaacaat ggcataagtc
    24001 aaatttaaga aaaaagccac ccaaacagca tattttgcct tcatatttct cattcctttg
    24061 ttataatagg tttatgaaca ccttgttcat tatcattatc cactaaaact caaagaaagg
    24121 atagaagcaa aacgtcagct ttattcagtt ctgaacaatt tgccttaagt gtccatatga
    24181 ctaacattga ccgccgtatc agcaaaacca aaaaagccat ctatcaagct tttatacaac
    24241 ttttgaatgc taagggctac gaggccacta ctgttcagga tatcattgat ctcgcagatg
    24301 tgggaagatc caccttttac tgtcactatg aaagtaagga gcttcttctg gaccagctct
    24361 gccgctacct cttccatcat ctttttgaaa gagagcaagc catttcaacc gaggactacc
    24421 tcgcccacct ctttctccat tttcataaaa accaagacca tatcaccagt ctgctatttt
    24481 ccaaaaatga ctacttcctc cgtcaactcc ataaagagct agaacaccat gtctattccg
    24541 tgctagctga taatttaaaa gaagcccacc ctaatatgcc tacttcttac ctccaacact
    24601 tggtcgtgtc caactttatc gagacattga cctggtggct caaaaaaggt caagatttca
    24661 cagaccagga agttgtccaa ttttatctag accttctcat tcctaaaaat tgaatataga
    24721 gtaaagctca gttgtcttat ttctaggtta ctgagttttt tatcttttca acaacaaaag
    24781 aggacccgcc gatcctcttt ttcatactat aaatccttga ttatcaacta tatctgtttt
    24841 aatcgaaatc tcaaaacagc actttcaaac atcttttcct agttaggtaa atcagtattc
    24901 tgcttagctg ccttgctcca ttgataccaa ccaactagac tgttaatgag ataaattaga
    24961 tatttccctt gaatttgcag gctttctccc caccagagat agattgaaaa aacattggta
    25021 gccgcccaga atatccactg ttcacggtaa acagctgtca tgaggatttg ccctacccca
    25081 ttggttgcat ctgtgattga atcacgatag ggacgattgg caccaataga ctgataaatg
    25141 aagccaaagg ccaaccacca aagcacacta atggaaagat actttgtcca gcccttgccg
    25201 tccagtttac gcgcgacaaa ctcctgcttt tccttcttaa actgtgcctg ataaatccaa
    25261 actagaagtc caattggctg catgactgtg aagtaaagtg tcgtcagcac ctcaccataa
    25321 aagcctttct gtagggccaa aataaggtaa ataacagagt taatcaagcc aaaaagataa
    25381 ttacttgctc gaccttccga tacaaagatt acacagataa tccctgtcaa gctacaaatc
    25441 atcccaatcc agtcaacaat acgatgttcg taaaccaact ccagccagag aggaaaactt
    25501 cctaaaacca gcaaataaat ccactgggca aaactacgat gggcaaagag gtcatcccag
    25561 atagccttca tagttcctga aaatcctaaa tcagccatag ccgcaaccat acgacggtaa
    25621 ccacctgaca tttcacctag ggttgttttg atattttcaa ttttcttttg caaataagta
    25681 tgcatcattt ctccttttgt ttttaaagag ccgtgtctgg atagactttc ggacgcaacg
    25741 ctctattaga taatgaactg cctatacaca agatttctaa ccttagtcga catgagctga
    25801 aacctcttat ttgttaagta gttcacaaaa tattatacac ctattttatg aatagtcaac
    25861 tgtctttaca gtaaaatttt agaaaatcat gaaaattttc tctttctttc cattttaagt
    25921 gacattcagt cattctcaca tcaaaaaagc ccagacgaaa ctgtctgagc attcttttat
    25981 ctagtcgttt aaggaagttg agttcagtat gttt
//
LOCUS       DAVBOG010000029        25830 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.029, whole genome shotgun sequence.
ACCESSION   DAVBOG010000029 DAVBOG010000000
VERSION     DAVBOG010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25830
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.029"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            59..772
                     /locus_tag="VQ865_001309"
     CDS             59..772
                     /locus_tag="VQ865_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HET3135640.1"
                     /translation="MFYKFLLFDLDHTLLDFDAAEDVALTQLLKEEGVADIQAYKDYY
                     VPMNKALWKDLELKKISKQELVNTRFSRLFSHFGQEKDGSFLAQRYQFYLAQQGQTLS
                     GAHDLLDSLIERDYNLYAATNGITAIQTGRLAQSGLVPYFNQVFISEQLQTQKPDALF
                     YEKIGQQIAGFSKEKTLMIGDSLTADIQGGNNAGIDTIWYNPHHLENHTQAQPTYEVY
                     SYQDLLDCLDKNILEKITF"
     gene            786..1433
                     /locus_tag="VQ865_001310"
     CDS             786..1433
                     /locus_tag="VQ865_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001813281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135641.1"
                     /translation="MTTKKANITIEEYIEMSEVDFNEAVNYEFTSDTCQLANSIYQSL
                     FKFFDKKNFSGDLIFTWKSPSLVKEGDYIGRRDSQVDNLRVIGNIFPNYLTNRKYSLN
                     MNRNGCMGDFPHDFFDIYLDHVAKYAYEQKVNNIKEYYPLKRAILHQENALYFRFFSN
                     FDDFLEKNYLKTIWQVSKETPFSEMDFNMFKNISEKIIFERGSKMLNDLKSNYKK"
     gene            1571..2224
                     /locus_tag="VQ865_001311"
     CDS             1571..2224
                     /locus_tag="VQ865_001311"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001841111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HET3135642.1"
                     /translation="MEHSSWHALIKAQLPEGYFGKINQFMEQVYSQGIIYPPKEKVFQ
                     ALLTTLLEEVKVVILGQDPYHGPGQAQGLSFSVPDSIPAPPSLQNILKELSDDIGVKK
                     SHDLTSWAEQGVLLLNACLTVPAGQANGHAGQIWEPFTDAVIQVVNHLDRPVVFVLWG
                     AYARKKKALVTNPHHLIIESAHPSPLSVYRGFWGSKPFSKANAFLKETGQEPIDWLR"
     gene            2234..2698
                     /locus_tag="VQ865_001312"
     CDS             2234..2698
                     /locus_tag="VQ865_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003012002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase"
                     /protein_id="HET3135643.1"
                     /translation="MPQLATICYIDNGKELLMLHRNKKPNDVHEGKWIGVGGKLERGE
                     TPQECAAREILEETGLKAKPVLKGVITFPEFTPDLDWYTYVFKVTEFEGDLIDCNEGT
                     LEWVPYDEVLSKPTWEGDHTFVEWLLEDKPFFSAKFVYDGDKLLDTQVDFYE"
     gene            2711..3979
                     /locus_tag="VQ865_001313"
     CDS             2711..3979
                     /locus_tag="VQ865_001313"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HET3135644.1"
                     /translation="MLLIKNGRVMDPKSGLDQVCDVLVQDGKIIKIAPEITEEGAETI
                     DATGLVVAPGLVDIHVHFREPGQTHKEDIHTGALAAAAGGFTTVVMMANTSPTISDVE
                     TLQAVLQSAAKEKINVKTVATITKNFNGKNLTDFKALLEAGAAGFSDDGIPLESSKIV
                     KEAMEEAKKLNTFISLHEEDPGLNGVLGFNENIAREHFHICGATGVAEYAMMARDVMI
                     AYATKAHVHIQHLSKEESVKVVEFAQGLGAEVTAEVAPQHFSKTEALFLTQGSNAKMN
                     PPLRLESDRRAVIEGLKSGVITVIATDHAPHHVDEKNVEDITKAPSGMTGLETSLSLS
                     LTYLVEAGELSLMELLEKMTYNPAKLYNFEAGYLAENGPADITIFDAKADRLVDSHFA
                     SKAANSPFIGETLKGQVKYTICKGQIVYQA"
     gene            3993..4253
                     /locus_tag="VQ865_001314"
     CDS             3993..4253
                     /locus_tag="VQ865_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135645.1"
                     /translation="MNYFRKRRERQAKSNSGIYCPAANRSKIQYETKEKADHAVQYDN
                     GGLVRSYYCRTCACWHTTSKSNKPPLSLKNYGLKLFGLDKSE"
     gene            4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ865_001315"
     CDS             4264..5625
                     /gene="pdrM"
                     /locus_tag="VQ865_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-coupled multidrug efflux MATE transporter
                     PdrM"
                     /protein_id="HET3135646.1"
                     /translation="MYKTKCLREKLVLFLKIFFPILIYQFANYSASFVDTAMTGQYNT
                     MDLAGVSMATSIWNPFFTFLTGIVSALVPIIGHHLGRGKKEEVASDFYQFIYLALGLS
                     VVLLGMVLFLAPTILNHIGLEAAVAAVAVRYLWFLSIGIIPLLLFSVIRSLLDSLGLT
                     KLSMYLMLLLLPLNSGFNYLLIYGAFGVPELGGAGAGLGTSLAYWVLLGISVLVLFKQ
                     EKLKALHLEKRIPLNMDKIKEGVRLGLPIGGTVFAEVAIFSVVGLIMAKFSSLIIASH
                     QSAMNFSSLMYAFPMSISSAMAIVVSYEVGAKRFDDAKTYIGLGRWTALIFAAFTLTF
                     LYIFRGNVASLYGNDPKFIDLTVRFLTYSLFFQLADTFAAPLQGILRGYKDTVIPFYL
                     GLLGYWGVAIPVATLFDSLTDFGAYSYWIGLIISLIVSGALYRWRLTVIMKRFESLAK
                     SKR"
     gene            5779..6747
                     /locus_tag="VQ865_001316"
     CDS             5779..6747
                     /locus_tag="VQ865_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine pyrophosphate-dependent dehydrogenase
                     E1 component subunit alpha"
                     /protein_id="HET3135647.1"
                     /translation="MSTLDKNLLLEMFRKMEEIRRMDLKIAQLVKKGKVPGMTHFSVG
                     EEAANVGAMLALNPDDLITSNHRGHGQAIAKGIDLNGMMAEILGKYTGTCKGKGGSMH
                     IADLDAGNLGANGIVGGGMGIAVGAALSQQMQNTGKIVVCFFGDGATNEGVFHEAVNM
                     ASIWNLPVIFYCINNGYGISADIKKMTNIEHIHQRSAAYGIPGMFIEDGNNVIDVYEG
                     FQKAVDHVRSGNGPVLIESVTYRWLGHSSSDPGKYRTREEVELWKQKDPIENLRNYLI
                     ENNIASAEELEEIQAQVKEAVEASVKFAEESPFPPLESAFEDIYAD"
     gene            6763..7755
                     /locus_tag="VQ865_001317"
     CDS             6763..7755
                     /locus_tag="VQ865_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000448722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HET3135648.1"
                     /translation="METKTMSFRDTIILAMSEEMRRDENVFLMGEDVGVFGGDFGTSV
                     GMLEEFGPERVRDCPISEAAISGAAAGAAMTGLRPIVDMTFMDFSVIAMDNIVNQAAK
                     TRYMFGGKGQVPMTVRCAAGNGVGSAAQHSQSLESWFTHIPGLKVVAPGTPADMKGLL
                     KSSIRDKNPVIILEYKSEFNQKGEVPVDPDYTIPLGVGEIKRQGTDVTVVTYGKMLRR
                     VVQAAEELAEEGISVEIVDPRTLVPLDKDIIINSVKKTGKVVLVNDAHKTSGYIGEIS
                     AIISESEAFDYLDAPIRRCAGEDVPMPYAQNLENAMIPTVESIKDAIRKTYNKE"
     gene            7973..9016
                     /locus_tag="VQ865_001318"
     CDS             7973..9016
                     /locus_tag="VQ865_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide acetyltransferase"
                     /protein_id="HET3135649.1"
                     /translation="MADDKLRATPAARKLADDLGINLYDVSGSGANGRVHKEDVETYK
                     DTNVVRISPLAKRIALEHNIAWQEIQGTGHRGKIMKKDVLALLPENIENDSIKSPAQI
                     EKVEEVPDNVTPYGEIERIPMTPMRKVIAQRMVESYLTAPTFTLNYEVDMTEMLALRK
                     KVLEPIMEATGKKTTVTDLLSLAVVKTLMKHPYINASLTEDGKTIITHNYVNLAMAVG
                     MDNGLMTPVVYNAEKMSLSELVVAFKDVIGRTLDGKLAPSELQNSTFTISNLGMFGVQ
                     SFGPIINQPNSAILGVSSTIEKPVVVNGEIVIRPIMSLGLTIDHRVVDGMAGAKFMKD
                     LKELIETPISMLI"
     gene            9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ865_001319"
     CDS             9080..10765
                     /gene="lpdA"
                     /locus_tag="VQ865_001319"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HET3135650.1"
                     /translation="MPKAGVDMTEGQIVQWNKKVGEFVKEGEILLEIMTDKVSMELEA
                     EEDGYLIAILKGDGETVPVTEVIGYLGEERENIPTAGAASPEASSVPVASTSNDDDKS
                     DDAFDIVVIGGGPAGYVAAIKAAQFGGKVALVEKSELGGTCLNRGCIPTKTYLHNAEI
                     IENIGHAANRGIVIENPNFTVDMEKLLETKSKVVNTLVGGVAGLLRSYGVTVHKGIGT
                     ITKDKNVLVNGSELLETKKIILAGGSKVSKINVPGMESPLVMTSDDILEMNEVPESLV
                     IIGGGVVGIELGQAFMTFGSKVTVIEMMDCIVPAMDAEVSKNLRLILERKGMTILTGT
                     KLQEIIEENGQLRIKVEGKDDIIASKALLSIGRMPDLEGIGEVEFELDRGCIKVNEYM
                     ETSVPGIYAPGDINGTKMLAHAAFRMGEVSAENALKGNHAIAKLNLTPAAIYTLPEVA
                     AVGLTEEQAREKYDVAIGKFNFAANGRAIASDAAQGFVKVIVDKKYGEILGVHIIGPA
                     AAELINEASSIIEMEITVEEMLKTIHGHPTYSEVMYEAFADVLGMAIHSPKKK"
     gene            10829..11818
                     /locus_tag="VQ865_001320"
     CDS             10829..11818
                     /locus_tag="VQ865_001320"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HET3135651.1"
                     /translation="MKYIINHSNDTAFNIALEEYAFKHLLDEDQIFLLWINKPSIIVG
                     RHQNTIEEINRDYVRENGIEVVRRISGGGAVYHDLNNLNYTIISKEDENKAFDFKSFS
                     TPVINTLAQLGVKAEFTGRNDLEIDGKKFCGNAQAYINGRIMHHGCLLFDVDLSVLAN
                     ALKVSKDKFESKGVKSVRARVTNIINELPKKITVEKFRDLLLEYMKKEYPEMTEYVFS
                     EEELAEINRIKDTKFGTWDWNYGKSPEFNVRRGTKFTSGKVEVFANVTESKIQDIKIY
                     GDFFGIEDVAAVEDVLRGVKYEREDVLKALKTIDITRYFAGISREEIAEAVVG"
     gene            complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ865_001321"
     CDS             complement(11891..12961)
                     /gene="xerS"
                     /locus_tag="VQ865_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000817875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HET3135652.1"
                     /translation="MKREILLERIDKLKQLMPWYVLEYYQSKLAVPYSFTTLYEYLKE
                     YDRFFSWVLESGISNADKISDIPLSVLENMSKKDMESFILYLRERPLLNANTTKQGVS
                     QTTINRTLSALSSLYKYLTEEVENDQGEPYFYRNVMKKVSTKKKKETLAARAENIKQK
                     LFLGDETAGFLTYIDQEHPQQLSNRALSSFNKNKERDLAIIALLLASGVRLSEAVNLD
                     LRDLNLKMMVIDVTRKGGKRDSVNVAAFAKPYLENYLAIRNQRYKTEKTDTALFLTLY
                     RGVPNRIDASSVEKMVAKYSEDFKVRVTPHKLRHTLATRLYDATKSQVLVSHQLGHAS
                     TQVTDLYTHIVNDEQKNALDSL"
     gene            complement(13455..15005)
                     /locus_tag="VQ865_001322"
     CDS             complement(13455..15005)
                     /locus_tag="VQ865_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chloride channel protein"
                     /protein_id="HET3135653.1"
                     /translation="MEEQSEIVRSKKEFAFASSTILSQVGRGIIVGLIVGIIVGSFRF
                     LIEKGFHLIQGVYQDQGYLVRNLFVLVLFYILICWLSAKLTRSEKDIKGSGIPQVEAE
                     LKGLMSLNWWGILWKKYVLGILAIASGLMLGREGPSIQLGAVGGKGIAKWLKSSPVEE
                     RSLIASGAAAGLAAAFNAPIAALLFVVEEVYHHFSRFFWVSTLAASIVANFVSLLMFG
                     LTPVLDMPDNIPPMTLDQYWIYLVMGIFLGFSGFLYEKAVLNVGRVYDLIGQKIHLDR
                     AYYPILAFILIIPVGIFLPQIIGGGNQLVLSLTEQNFSFQVLLAYFLIRFIWSMISYG
                     SGLPGGIFLPILALGSLLGALVGVICVNLGLVSQEQFPIFVILGMSGYFGAISKAPLT
                     AMILVTEMVGDIRNLMPLGLVTLVSYIIMDLLKGTPVYEAMLEKMLPEEVSSEGEVTL
                     IEIPVSDKIAGKQVHELNLPHNVLITTQVHNGKSQTVNGSTRMYLGDMIHLVIPKSEI
                     GKVKDLLL"
     gene            complement(15021..15800)
                     /locus_tag="VQ865_001323"
     CDS             complement(15021..15800)
                     /locus_tag="VQ865_001323"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HET3135654.1"
                     /translation="MATIKEIKELLVTVKELESPIFLELEKDNRSGVQKEISKRKRAI
                     QAELDENLRLESMLSYEKELYKQGLTLIAGIDEVGRGPLAGPVVAAAVILPKNCKIKG
                     LNDSKKIPKKKHLEIFQAVQDQALSIGIGIIDNQVIDQVNIYEATKLAMQEAISQLSP
                     QPEHLLIDAMKLDLPISQTSIIKGDANSLSIAAASIVAKVTRDELMKEYDQQFSGYDF
                     ATNAGYGTAKHLEGLTKLGVTPIHRTSFEPVKSLVLGKKES"
     gene            complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ865_001324"
     CDS             complement(15787..16638)
                     /gene="ylqF"
                     /locus_tag="VQ865_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000201313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HET3135655.1"
                     /translation="MATIQWFPGHMSKARRQVQENLKFVDFVTILVDARLPLSSQNPM
                     LTKIVGDKPKLLILNKADLADPAMTKEWRQYFESQGIQTLAINSKEQVTVKVVTDAAK
                     KLMADKIARQKERGIQIETLRTMIIGIPNAGKSTLMNRLAGKKIAVVGNKPGVTKGQQ
                     WLKTNKDLEILDTPGILWPKFEDETVALKLALTGAIKDQLLPMDEVTIFGINYFKEHY
                     PEKLAERFKQMKIEEEAPVIIMDMTRALGFRDDYDRFYSLFVKEVRDGKLGNYTLDTL
                     EDLDGND"
     gene            complement(16720..18228)
                     /locus_tag="VQ865_001325"
     CDS             complement(16720..18228)
                     /locus_tag="VQ865_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000291919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HET3135656.1"
                     /translation="MYYVTKTNSKGQPLYQVVEKYKDPLTGKWKSVTVSYTKNTSRAR
                     KQAEREVLDKIDRLTTSFESQFSPELITTFGELKENWFQTWCVSVKPQTIQRELLVMK
                     RLGKIIGDDFLLDRITPLLMKKSLNKYLEIYDASPSTMTHIKSTCNKIFNHGVLYNVI
                     KFSPMTAVKLDISLEKRRKAKERHDSKFLEIHELHAFFDVLSQCRNANYYDLAIVLLL
                     TGIRISEAAFLPSDIDFEKGILHIDKALQYHCLKVEQFHFDTTKTLNSIREVALPEAA
                     SEAIKRTIQRNKEFDAYMEKHPCPAFTHSESVFRTEYGSPITSSTFRQILKRIEGKLL
                     TNCLSDYGFKWVKHVTPHSFRHMHISYLQSNEMHIAVKDIMTRVGHANFETTMGYTHN
                     INRSQENTVKALNQFVENHNFHFEELKSYTCKYSRIIEKFIETSDNSNKVEFSVDEFK
                     DLLHLSPRYSPKNIISNLLLKIKKDIVKYHPQFDIKIVKSSENQIRGFSIAW"
     gene            complement(18313..18546)
                     /locus_tag="VQ865_001326"
     CDS             complement(18313..18546)
                     /locus_tag="VQ865_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000693750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HET3135657.1"
                     /translation="MNIKYISVENSIAEWADKKGILKRWDGLNQYTLNRWIKEMRENR
                     TFSMYVINPTHKLVFINLEGFESFLRWKQKRTK"
     gene            complement(18816..19040)
                     /locus_tag="VQ865_001327"
     CDS             complement(18816..19040)
                     /locus_tag="VQ865_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135658.1"
                     /translation="MLKRIRDLREDDDLTQEYIAKIVLNCTRSSYSKMEAGSRLISIN
                     DLIKLADFYKVSLDYLVGRVDNKEDHYSKK"
     gene            complement(19144..20973)
                     /locus_tag="VQ865_001328"
     CDS             complement(19144..20973)
                     /locus_tag="VQ865_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HET3135659.1"
                     /translation="MVITKHFAIHGKNYRSKLIKYILNPSKTKNLTLVSDFGMRNYLD
                     FPSYEELVKMYNDNFLSNDTLYEFRHDRREVNQRKIHSHHIIQSFSPDDHLTPEQINQ
                     IGYETVKELTGGRFRFIVATHMDKDHIHNHIILNSIDQNSDKKFLWDYKSERNLRMVS
                     DRLSKIAGAKIIENRYSHRQYEVYRKTNYKYEIKQRVYFLIENSKNFEDFKKKAKALH
                     LKIDFRHKHVTFFMTDSNMKQVVRDSKLSRKQPYNETYFKKKFVQREIINILEFLLPK
                     MKNMNELIQRAEFFGLKIIPKEKHVQFEFDEIKISEQELVKANRYSVSYFQNYFNNKN
                     ETVVLDNKNLVELYNEEKLIKEKELPTEEVVWKSYQDFKRNRDAVHEFEVELNLNQIE
                     EVVDDGIYIKVQFGIRQEGLIFVPNIQINMEEEKVKVFLRETSSYYVYHKDSTEKNRF
                     MKGKTLIRQFNLQYEPQYMYRRIPLSKIKEKIEQLDFLVSAENSQNAFEDITKDFIAQ
                     ISYLENMIDHVQNKIDDLSNLEEVLLNDATNSSSNLENSIQGKSSVDTIEKDLYIYKG
                     KIETLKEQHREAINLFEMFNKTIKKYKKKQNTKSIKENEIHLE"
     gene            complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ865_001329"
     CDS             complement(20960..21325)
                     /gene="mobC"
                     /locus_tag="VQ865_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000401240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HET3135660.1"
                     /translation="MEHRYRTNLKKVFLSDLELVKLNENISKSNCLSFSEYARRTLLD
                     PGMNFITIDTNSYQDLIFELKRIGNNINQIARSINYSNLITEVELNELRKGIEELIVE
                     VEKDFLIQSEKLRKFYGHH"
     gene            complement(21330..21686)
                     /locus_tag="VQ865_001330"
     CDS             complement(21330..21686)
                     /locus_tag="VQ865_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012775541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135661.1"
                     /translation="MKRDIRSIRKQFRLTETEEKQILDLMREKGEDNFSDFLRKSLLL
                     SDGQKQMEKWFNLWKKQKLEQISRDVHEVFIIAKTNHQVTHEHVSILLTCIQELIKEV
                     EKTGPLSEDFRNKYMR"
     gene            complement(21982..22272)
                     /locus_tag="VQ865_001331"
     CDS             complement(21982..22272)
                     /locus_tag="VQ865_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135662.1"
                     /translation="MNRKELYDDKLQLDYFSDSYLQFESDFYKYSALDIPLTFITDDI
                     LRTMAMSQKHYFKLNKSKSLDGRDHYFVFSIKMNKDSSGIRQYEYQRHCFNL"
     gene            complement(22262..22627)
                     /locus_tag="VQ865_001332"
     CDS             complement(22262..22627)
                     /locus_tag="VQ865_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135663.1"
                     /translation="MMNRSYLPFESARVYQDRGMAKWMGFFLSEHSSSLWAEKNKEDI
                     SISLSLEEKVLFVRQLYTNVFPATFVFKFSNQRKVVSGIVKEIGKEFISIKSDTGFLR
                     LKWEDILDIQIEGEELHES"
     gene            complement(22624..24039)
                     /locus_tag="VQ865_001333"
     CDS             complement(22624..24039)
                     /locus_tag="VQ865_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006149971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HET3135664.1"
                     /translation="MSWFDYSLEPQSDIAFIDMKSFYASVECVDRGLHPLKTSLCVMS
                     RADNSAGLILASSPMFKKVFGKSNVGRSYDLPFDVKTRKFSYYNARKQGLPTTIDYVR
                     YIEEWAKSTVIVPPRMDTYIAVNMEIQKIFQEFAAPDDIYPYSIDEGFIDLTSSLNYF
                     VPDKRISRKDKLDIISAAIQKKIWRKTGIYSTVGMSNANPLLAKLALDNEAKKTPTMR
                     ANWSYEDVEKKVWTIPKMTDFWGIGNRTEKRLHNLGIFSIKELAQANPDLIKKELGIM
                     GLELWFHANGIDESNVHKPYKPKSKGIGNSQVLPKDYIKQRDIEIILREMAEQVAVRL
                     RRSGKKATVVSIHLGYSKVEQKRSINTQMKIEPTNQTALLTNYVLKLFHTKYTSGAIR
                     NVAVNYSGLVDESFGLISLFDDIEKIEKEERLQSAIDAIRTEFGFTSLLKGNALDQAS
                     RTIARSKLIGGHSAGGLDGLK"
     gene            complement(24042..24725)
                     /locus_tag="VQ865_001334"
     CDS             complement(24042..24725)
                     /locus_tag="VQ865_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135665.1"
                     /translation="MFSPTKLKEKRESQGLSQSQLASSLGISRASYFNWESGKTKPNQ
                     NNLSKLSEIFNVDPRYFESEFEIVETYLKLTKKNQKATLHYATELLNKQNAKVVEIPE
                     RFAYKVYEKLSAGTGTAYFDDGNYDTVYFNRQFDYDFASWVSGVSMEPTYKNGSVALI
                     KQTGFDYDGAIYAIDWDSQTFIKKVYREENGLRLVSLNRNYPDKFAPYDENPRIIGKI
                     VGNFMPLED"
     gene            complement(24953..25723)
                     /locus_tag="VQ865_001335"
     CDS             complement(24953..25723)
                     /locus_tag="VQ865_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HET3135666.1"
                     /translation="MEIQDYTDSEFKHALTRNLRSLTRGKKSSKQPIAILLGGQSGAG
                     KTTIHRIKQKEFQGNIVIIDGDSFRSQHPRYLELQQEYGKDSVEYTKDFAGKMVESLV
                     TELSHLGYNLLIEGTLRTIDVPKKTAQLLKSKGYEVQLALIATKPELSYLSTLIRYEE
                     LYSINPNQARATSKEHHDFIVNHLVDNTRQLEELAIFERIQIYQRDRSCVYDSKENTT
                     SAATVLHDLLFGEWNQVEKEMLKSGEERLKDLTNRNGL"
     gene            complement(25723..>25830)
                     /locus_tag="VQ865_001336"
     CDS             complement(25723..>25830)
                     /locus_tag="VQ865_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3135667.1"
                     /translation="TNIYLVETFDEIERYSGYLDGIERMLEISEKRMVA"
BASE COUNT         7820 a         4828 c         4813 g         8369 t
ORIGIN      
        1 tatgaggtgc tttatgatat aatgttctta atgaattttc agaaaggaaa acctcaaatt
       61 gttctacaaa tttctactct tcgacctcga ccacactctt cttgattttg atgctgctga
      121 ggatgtggct ttgacccaac ttctaaaaga agaaggagtt gcggatattc aggcttataa
      181 agattattac gttcctatga acaaggctct ctggaaagac ttggagctga agaaaatcag
      241 taaacaagag ctggttaaca cgcgcttttc tcgtttattt tctcattttg gacaggaaaa
      301 agacggtagt tttcttgccc agcgttacca attttatctc gctcagcagg gacaaacact
      361 atcgggcgct catgatctct tggacagcct cattgagcgt gattataact tgtatgctgc
      421 gacaaatggc attactgcca ttcagacagg acgtttggct caatctggtc tagtacctta
      481 tttcaatcaa gtctttatct cagaacagtt gcaaactcaa aagccggatg ctctctttta
      541 tgaaaagatt ggccagcaaa ttgctggatt tagtaaagaa aagacgctga tgattggaga
      601 ttctctaacc gccgacattc aaggtggcaa taatgcgggg attgacacta tctggtataa
      661 tcctcatcac ctcgaaaatc acacacaagc ccagccgact tacgaagtct attcttacca
      721 agacttgctg gattgtttag ataaaaatat tcttgaaaag atcacatttt aaaggagatt
      781 agctaatgac tacaaaaaaa gctaatatta ctattgaaga gtacattgaa atgtctgaag
      841 ttgattttaa tgaagctgtt aattatgaat ttacatctga cacttgtcaa ttagcaaata
      901 gtatttatca atctcttttt aagttttttg ataagaaaaa tttctctggc gatttaattt
      961 ttacttggaa atctccatca ttagtcaaag aaggggatta tattgggaga agggattcac
     1021 aagtagataa tcttagagta ataggaaata tatttccgaa ttatcttact aatcgaaaat
     1081 atagcctcaa tatgaatcgt aatggctgta tgggagattt tcctcatgac ttttttgata
     1141 tatacctaga tcatgtagca aaatatgcct acgaacaaaa agttaataat attaaagagt
     1201 attatccttt aaaaagagcg attttacacc aagagaatgc attgtatttt cgattttttt
     1261 ctaattttga cgacttttta gaaaaaaatt atttaaagac tatatggcaa gtttctaaag
     1321 aaactccttt ttctgaaatg gattttaata tgtttaaaaa tatttcagaa aagataatct
     1381 tcgaaagagg tagtaaaatg cttaatgatt taaaaagtaa ttataaaaaa tagccagtct
     1441 ttataaactg tattcacgta ttcaaatcgt atatatagtc gatttattaa atctttagat
     1501 aaactgtaaa aagtggtttc catagccact ttttgctata atagaggcag taaaaatgaa
     1561 ggagtcggct atggaacact cgtcttggca tgctttgatt aaggcgcaat tacctgaggg
     1621 ttatttcggg aaaatcaatc agtttatgga gcaggtctat tctcagggga ttatttatcc
     1681 acccaaggaa aaggtttttc aggctctctt gacaacactg cttgaagaag ttaaggtggt
     1741 aattctaggg caagacccct atcacggacc aggtcaagcg cagggcttga gtttttctgt
     1801 acctgactct atcccagctc caccatcctt gcaaaatatc ttgaaagaat tgtcagatga
     1861 tatcggagtt aagaaatctc atgatttgac atcttgggct gagcaaggag tcttgcttct
     1921 taatgcttgt ttgactgttc ctgctggaca ggccaatggt catgctggtc aaatctggga
     1981 gccttttact gatgctgtga ttcaggtggt caatcatcta gatagaccag tcgtttttgt
     2041 actctgggga gcttatgcac gtaagaagaa ggcattagtt accaatcctc atcacttgat
     2101 tatcgaatca gcccatccaa gtcctttgtc ggtttataga ggattttggg gttccaagcc
     2161 cttttccaag gccaatgcat tcttaaaaga gacaggacaa gagccaatcg attggcttag
     2221 ataaggagaa aatatgcctc agttagcgac gatttgctac attgataatg ggaaagaact
     2281 gctcatgctc catcgtaata agaaacccaa tgatgtccat gaagggaaat ggattggtgt
     2341 gggtggtaag ctagagagag gagagacgcc ccaggaatgc gcggcgcgtg aaatccttga
     2401 agaaacaggg ctcaaagcca agccagttct aaaaggtgtc atcacttttc ctgaatttac
     2461 accagattta gactggtaca cctatgtttt taaggtgacg gagtttgagg gcgacttgat
     2521 tgactgcaat gaggggacgc tagaatgggt tccctatgat gaggttttga gcaagccgac
     2581 ttgggaaggt gaccacacct ttgttgagtg gcttttagag gataaaccct tcttttcagc
     2641 caagtttgtt tatgatgggg ataaattgtt ggatacccaa gttgatttct atgaataaag
     2701 gagaaagcag atgctactaa tcaaaaatgg tcgtgtaatg gatcccaagt ctggtttgga
     2761 tcaagtttgt gatgtcttag ttcaagatgg gaaaattatc aaaattgcgc ctgagatcac
     2821 ggaagaagga gcagaaacga ttgatgctac tggtcttgtg gttgctcctg gtttggtcga
     2881 tattcatgtg catttccgtg aacctggtca aacacataaa gaagacattc atactggtgc
     2941 cctggcagcc gctgcaggtg gttttactac tgtcgtcatg atggctaata ccagtccaac
     3001 catttcagac gtggagactt tgcaagcagt tctccagtca gctgccaaag agaagattaa
     3061 tgtcaagaca gttgcgacca ttactaaaaa ctttaatggt aaaaacttga ctgactttaa
     3121 ggcgctctta gaagctggtg cggctggttt ctctgatgac ggtattccgc ttgagagcag
     3181 taagattgtc aaggaagcca tggaggaagc caaaaaactc aataccttta tcagccttca
     3241 tgaggaagat ccaggtttga acggtgttct tggctttaat gaaaatattg ctagagaaca
     3301 tttccatatc tgcggtgcta ctggggtggc tgagtacgct atgatggcgc gtgatgtcat
     3361 gattgcctat gcaactaaag cccatgttca catccagcat ttgtctaagg aagaaagtgt
     3421 taaagtagtg gagtttgctc aggggttagg tgcagaagtc acagcagaag tagcgccaca
     3481 gcatttctct aagacagaag cacttttttt aacacaaggt agcaatgcta agatgaatcc
     3541 accgcttcgt ttggaatcag accgtcgtgc cgttatcgaa ggtctcaaat caggtgtcat
     3601 cacagttatt gcgactgacc acgcccctca tcatgtagat gaaaaaaatg ttgaggatat
     3661 taccaaagcg ccatctggta tgactggctt agaaacatcc ctgtctctca gcttgaccta
     3721 tttagtagaa gctggtgagt tgagcttgat ggaattactt gaaaaaatga catacaaccc
     3781 agccaagctt tacaactttg aagcaggtta cttggctgag aatggtccag cagatatcac
     3841 tatttttgat gccaaggctg accgccttgt ggactcccat tttgcttcca aagcagctaa
     3901 ttcaccattc atcggtgaaa ccttaaaagg gcaggttaaa tataccatct gtaagggaca
     3961 aatcgtctat caagcttgat aggagttaga atatgaatta ttttcgaaaa cgtagggaga
     4021 gacaagcgaa atctaatagt ggaatttact gtcccgcagc taatcgttcc aaaattcaat
     4081 atgaaactaa agaaaaagct gaccatgcgg ttcaatatga taacggaggt ttagttagaa
     4141 gctattattg tcgtacatgt gcgtgttggc atactacttc aaaatctaat aaacctccgc
     4201 taagtttgaa aaactatggt ctgaaactct ttggtttaga taaatcagaa tagaaagaga
     4261 agtatgtata agacaaagtg tttacgagag aagttagtat tatttttaaa aattttcttc
     4321 ccaatcctga tttaccaatt tgccaattat tctgcctctt ttgttgatac tgcaatgaca
     4381 ggtcaataca acactatgga cttggctggt gtatctatgg caaccagtat ctggaatcct
     4441 ttctttacat ttctaacagg gattgtgtca gccttggtgc ctatcattgg tcaccatctt
     4501 ggtcgaggaa aaaaggaaga agttgcgtct gatttttacc aatttattta tttggccttg
     4561 ggcctatctg tggtattgct ggggatggta ctttttttgg caccaacaat cttgaatcat
     4621 attgggttag aagcagcagt agcggcagta gcggttcgct atctttggtt tttatctatc
     4681 gggattatcc ccttgttgct ctttagcgtc attcgttcct tgctggattc gctgggcttg
     4741 accaaactgt ccatgtacct catgcttttg ttactccctc tcaatagcgg atttaactat
     4801 ctcttgattt acggtgcctt tggtgttcca gaactgggag gggctggtgc tggtttagga
     4861 acatccttgg cctactgggt cttgcttggg atttctgttc tggttttatt taaacaggag
     4921 aagctcaaag ccttacacct tgagaaacga attccactta atatggataa aattaaggaa
     4981 ggagttcgtt taggtctgcc tattggggga actgtcttcg cggaagtggc tatcttttca
     5041 gtggttggct tgattatggc taagttttcg tccttgatta tagctagtca ccagtcagct
     5101 atgaactttt caagtcttat gtacgccttt cctatgagta tctcatcggc tatggctatt
     5161 gtcgtttcct atgaagtggg agccaagcga tttgatgatg cgaaaaccta tattggtcta
     5221 ggaagatgga ctgccctcat ttttgcggcc ttcaccttaa ccttccttta catttttagg
     5281 ggaaatgtgg ccagtcttta tggtaacgac ccaaaattta tcgatttgac agtgcgtttt
     5341 ttaacttata gtcttttctt ccagttagca gatacctttg cggcgccgct tcagggaatt
     5401 ttgcgggggt ataaggatac agttattcct ttttaccttg gtttgcttgg ttattggggc
     5461 gtagcaatcc ctgtggctac gctatttgat tctctaacag attttggagc ttattcttac
     5521 tggatcggct tgattattag tttgattgtg agtggggcgc tctaccgttg gcgtttaact
     5581 gtgattatga agagatttga atctttagca aaatccaaac gctaaaaagt ttgtgaaaaa
     5641 atattcttga taagaaaatc ccttgttttc acggggtttt cttttttatt ttgtgaaatt
     5701 tcttttagaa aaactttgac agtatttgcc aaaaacggta aaatagtaag gtaagaagaa
     5761 agttagaaag gcaagaagat gtcaacttta gataaaaatc ttttgctaga aatgttccgt
     5821 aagatggaag aaatccgtcg catggactta aaaattgcac aattagtaaa gaaagggaaa
     5881 gtgccaggaa tgacgcactt ttctgttggt gaagaggcag ctaacgtggg ggctatgtta
     5941 gctctcaatc cagatgatct gattacctca aaccaccgtg gacacgggca agctattgct
     6001 aaagggattg acctcaacgg aatgatggct gaaatccttg gtaaatacac tggaacctgt
     6061 aaagggaaag gtggatctat gcatatcgct gaccttgatg ctgggaacct tggtgccaat
     6121 ggtattgtag gtggtggtat ggggatcgct gtcggtgcag ccctcagtca gcaaatgcaa
     6181 aataccggta aaatcgttgt ctgcttcttt ggagatggtg cgaccaatga aggtgttttc
     6241 cacgaagcag tgaacatggc ttctatctgg aacctgccag tcattttcta ttgcattaac
     6301 aacggttacg gtatctctgc ggatatcaag aaaatgacca atatagaaca tatccatcaa
     6361 cgtagcgccg cttatggaat tcctggaatg ttcatcgaag atggtaacaa tgtcatcgat
     6421 gtctatgaag gatttcagaa agctgtggac catgttcgca gtggcaatgg tccagtcttg
     6481 attgaaagtg taacttatcg ctggctcggt cactcatcat ctgaccctgg taaatatcgt
     6541 acgcgtgaag aagtggaatt gtggaaacaa aaagatccaa tcgaaaacct ccgcaattac
     6601 cttattgaaa ataacattgc aagtgccgaa gaattggaag aaatccaagc gcaagtaaag
     6661 gaagcagtag aagcttctgt taaatttgca gaggaaagcc cattcccacc gcttgaatca
     6721 gcctttgaag atatttacgc agactaagga gaaagagata aaatggaaac aaaaacaatg
     6781 tccttccgtg acaccattat ccttgctatg tctgaggaaa tgcgtcgcga tgaaaatgtg
     6841 ttcttgatgg gagaagacgt cggtgtcttc ggaggagact tcggtacttc tgttggaatg
     6901 cttgaagaat ttggtccaga acgcgtccgt gactgtccga tttctgaagc tgccatctct
     6961 ggagcagcag caggagcagc catgacagga cttcgtccaa tcgtcgatat gaccttcatg
     7021 gacttctctg ttattgccat ggacaatatc gtcaaccaag ctgctaaaac acgttacatg
     7081 tttggtggta aaggtcaggt tccaatgact gttcgttgtg cagctggtaa cggagttggc
     7141 tctgccgccc agcactcaca atctctagag tcttggttta ctcacattcc aggacttaag
     7201 gttgtggcac ctggaacacc tgcggacatg aaaggcctgc ttaagtcttc tatccgtgat
     7261 aaaaacccag ttattatact tgagtacaag tcagaattta accaaaaagg ggaagtgcca
     7321 gttgatccag actacacaat tccacttggg gttggtgaaa tcaaacgcca aggaacggat
     7381 gtaacagttg ttacttatgg aaaaatgctt cgccgtgtgg ttcaagctgc tgaagaatta
     7441 gcagaagaag gaatttcagt tgaaattgtt gacccacgta cccttgttcc gcttgataag
     7501 gatatcatca taaactcagt gaagaagact ggtaaggttg ttctggtcaa cgatgcccac
     7561 aaaacaagtg gctatatcgg tgaaatttca gctattattt cagaatcaga agcatttgac
     7621 tatctagatg caccaattcg ccgttgtgca ggagaagatg tgccgatgcc ttatgcacaa
     7681 aacctagaaa atgcaatgat tccaacagtt gaaagtatca aagatgcaat ccgaaaaact
     7741 tataacaaag aatagagtta cataagataa gttatgtaaa taaaataaag ctgacgagaa
     7801 actttgtatc ttttaggtgc agagctcttc gtcattaata tcttagatta gagcacgggc
     7861 taaaagctcg gaaaaaagat aaatctcctt ggcttcatcg aagccatcgt cgatttccta
     7921 tttttcagtc gcttttgacg ccctttgtat cataaataga attggagagg tcatggctga
     7981 tgacaagcta agagcgactc ctgcagctag aaagttagcg gatgatttag ggataaacct
     8041 ctacgacgtt tctggctcag gtgcaaacgg tcgtgtccac aaagaagacg tggaaactta
     8101 taaagacaca aacgtggttc gcatttcgcc acttgcaaaa cgaattgccc tcgaacataa
     8161 cattgcttgg caggaaatcc aaggaaccgg tcatcgtggt aaaatcatga agaaggatgt
     8221 tttggccctg cttcctgaaa atatcgaaaa cgatagcatc aaatctcctg ctcagattga
     8281 aaaagtggaa gaagtccctg ataacgtaac accatatggt gaaatcgagc gtattccaat
     8341 gacaccaatg cgtaaggtta ttgcccaacg catggttgaa tcttacttga ctgcgccaac
     8401 cttcaccctc aactatgaag ttgatatgac tgaaatgttg gctcttcgta agaaggttct
     8461 tgagccaatc atggaagcaa ctgggaagaa gactactgta acagaccttc tttcgcttgc
     8521 agttgttaag actcttatga aacacccata catcaacgct tcattgacag aagatggcaa
     8581 gactattatc actcacaact atgtcaatct tgccatggca gttgggatgg ataatggatt
     8641 gatgacacct gttgtttaca atgctgagaa aatgagtctt tcagaactgg ttgtagcctt
     8701 taaggatgtt attggccgta ccttggatgg taaattggct ccaagtgagt tacaaaattc
     8761 aacattcaca atcagtaatt tgggaatgtt tggtgttcag tcctttggtc cgattattaa
     8821 ccaacccaac tcagctatcc ttggtgtcag ttcgacaatc gagaagccag ttgtcgtcaa
     8881 tggtgaaatt gtgattcgcc caatcatgag tttaggatta accattgacc accgtgtcgt
     8941 agatggtatg gctggtgcta agtttatgaa ggacttgaaa gagttgattg aaacgccaat
     9001 ctcaatgtta atttaagagc aagagtattc atttttaaga tatagataaa ggaaggaaga
     9061 catggcctta gaagtaatta tgccaaaagc cggcgtggat atgacagaag gacaaatcgt
     9121 ccaatggaat aaaaaagtcg gagaatttgt aaaagaagga gaaatccttt tggaaatcat
     9181 gactgataaa gtcagcatgg aattggaagc cgaagaagat gggtacttga ttgccattct
     9241 caaaggagat ggtgaaactg tccctgtaac ggaagttatc ggttaccttg gtgaagaaag
     9301 ggaaaacatc ccaacagctg gagcagcatc gccagaagct agctctgtac ctgtagcaag
     9361 tacctcaaac gatgatgata agagcgatga tgcttttgat atcgttgtga ttggtggagg
     9421 tcctgctggt tatgttgcag ccattaaagc tgcccaattc ggcggtaagg ttgcccttgt
     9481 tgagaaatct gaacttggtg gaacctgctt aaaccgtgga tgtattccaa ccaagaccta
     9541 ccttcataac gctgaaatta ttgaaaatat cggtcatgct gcaaatcgtg gtatcgtgat
     9601 tgaaaatcct aacttcactg ttgatatgga aaaactttta gaaactaaat ctaaagttgt
     9661 taatactctt gttggtggtg ttgcaggact tcttcgtagc tacggagtta ctgttcataa
     9721 aggaattggt acaatcacta aagacaagaa cgtcttggta aatggctctg aattgcttga
     9781 aaccaagaaa atcattcttg ctggtggttc aaaagtcagc aagatcaacg tccctggtat
     9841 ggaatctcca cttgtcatga ctagtgatga cattcttgaa atgaacgaag tgccagaaag
     9901 ccttgttatc atcggtggtg gagttgtcgg tatcgaactc ggtcaggcct tcatgacatt
     9961 tggttcaaaa gtgactgtta tcgaaatgat ggactgtata gttccagcta tggatgcgga
    10021 agtttctaag aaccttcgct tgatccttga gcgtaaagga atgaccatct tgactggtac
    10081 taaactgcaa gaaatcattg aggaaaatgg tcaacttcgt atcaaggttg aaggaaaaga
    10141 cgatatcatc gcaagcaaag ctcttctttc aattggtcgt atgccagacc ttgaaggtat
    10201 tggagaggtt gagtttgaat tggatcgtgg ttgtatcaag gtcaatgaat acatggaaac
    10261 ttcagttcca ggcatttatg caccaggtga catcaacggt actaagatgt tggctcacgc
    10321 agctttccgc atgggtgaag tttccgctga aaatgccctt aaaggaaatc atgcaattgc
    10381 caaattgaat ttgactcctg cagccatcta cactctccct gaagtagcag cagtaggttt
    10441 gacagaagaa caagcccgtg agaaatacga tgttgccatc ggtaagttta actttgctgc
    10501 taacggtcgt gctattgcat ctgacgctgc tcaaggtttc gtaaaagtta tcgttgataa
    10561 gaaatacgga gaaatccttg gtgtacacat tattggtcct gcagccgcag aattaataaa
    10621 cgaagcatca agcatcatcg aaatggaaat cactgttgag gaaatgctga agaccatcca
    10681 cgggcaccca acttactctg aagtgatgta cgaagcgttt gcagatgttc taggaatggc
    10741 catccattca cctaagaaaa aataaaacga agatagatta gactggaagg ttatttccag
    10801 tttctatcat ataaagtaaa gggatatcat gaaatacatt atcaatcatt caaatgacac
    10861 tgcttttaat attgccttgg aagaatacgc ctttaaacac cttttggatg aggatcaaat
    10921 cttcctactt tggattaaca agccatctat cattgttggt cgtcaccaga acactatcga
    10981 agaaatcaac cgtgattatg ttcgtgaaaa tggtattgag gtagttcgcc gtattagtgg
    11041 tggtggagct gtttaccacg atttaaataa cctcaactac acgatcatct ccaaagaaga
    11101 tgaaaataag gcatttgact tcaagagctt ctcaactccg gttatcaata ccctggctca
    11161 acttggggtt aaagctgagt tcacaggtcg taatgacctt gagattgatg gtaagaagtt
    11221 ctgtggcaat gcccaagcct atatcaacgg ccgtatcatg caccacggtt gcttgctctt
    11281 tgacgttgat ttgtcagtcc tcgcaaatgc ccttaaggtt tcaaaagata aatttgaatc
    11341 aaaaggtgtg aaatccgtcc gtgcccgtgt aaccaatatt atcaatgaat taccaaaaaa
    11401 aatcacagtc gaaaaattcc gtgatttact cttggaatac atgaaaaaag agtacccaga
    11461 gatgactgaa tacgtctttt cagaagaaga attggccgaa atcaatcgca tcaaggatac
    11521 taagtttgga acttgggact ggaactatgg taaatcacct gaatttaacg tccgtcgtgg
    11581 aaccaaattc actagtggta aggttgaagt ctttgctaac gttactgaat caaaaatcca
    11641 agacatcaag atttatggtg acttctttgg tattgaagac gttgctgcag tagaagatgt
    11701 ccttcgtggg gtgaaatacg aacgcgaaga tgttcttaag gcgctaaaaa ccattgatat
    11761 cacacgctac ttcgctggta ttagccgtga agaaatcgct gaagcggtag ttggataaat
    11821 caaaaagaag ttggccaact aaccaacttc tttttttgat atttatttac ataatttaaa
    11881 atacgtaaaa ttataaacta tctagagcat tcttttgttc atcattaaca atatgggtat
    11941 agaggtcagt gacttgtgtg ctggcatgtc ctagttggtg actgactaaa acttgtgatt
    12001 tagtcgcatc atagagccta gttgctagcg tatggcgcag tttatggggt gttacacgca
    12061 ctttaaaatc ctctgagtat ttagcaacca ttttctcaac gctagaagca tcgatacgat
    12121 taggaacacc tctgtagaga gttaaaaaaa gggctgtatc tgttttttcc gttttatagc
    12181 gttgattccg aatggccaga taattctcta aataaggttt agcaaaagca gcgacattga
    12241 ctgagtcacg tttgccacct tttcgagtaa catcaataac catcattttt agattgagat
    12301 ctcttagatc tagattaaca gcttcagata agcgaacacc agatgccaag agaagggcaa
    12361 taatggctaa atctcgttct ttatttttgt tgaatgatga gagagctcga tttgaaagct
    12421 gttgtgggtg ctcttgatcg atataagtta gaaaacctgc tgtttcatca cctagaaaga
    12481 gtttttgctt gatattttca gctctggcag caagggtttc tttctttttc ttggttgaaa
    12541 cttttttcat tacattacga tagaaataag gttccccctg atcattttca acctcctcgg
    12601 ttagatactt gtaaagacta gaaagtgctg ataaggttcg attgatagtt gtctgtgaaa
    12661 caccttgttt tgttgtatta gcattcagca agggacgttc acgtagataa aggataaagg
    12721 attccatgtc tttcttagac atattttcca aaactgataa aggaatatcg gatattttat
    12781 cagcgtttga aataccagac tccaaaaccc agctgaaaaa tcggtcatat tccttaaggt
    12841 attcgtacag ggttgtaaaa ctgtagggca cagccagttt agattggtag tattccagaa
    12901 cataccaggg catgagttgt tttagtttgt cgattcgttc cagtaaaatc tcacgtttca
    12961 tgtattttct ccataattaa gtatactagt agtatagcat agacttgtat atttttcaag
    13021 aaaattatag tttttcagaa agatgttata ggagtttttc aaagtgataa aaagacttag
    13081 acctacaaac aaaacagaat aaggaaaata ataaaaatct cacccactaa acttctgtta
    13141 atactacata gctagaaatt gatttgattg tcctgattgt tttatcctat ttctatttca
    13201 tttcactata taattgctat tgttttcttt ttcatgattt taatcttact gtacagattt
    13261 gatacagtaa actcctttct agctttatgc tttatcattt ctaacttaat tatagtctta
    13321 tttttaataa agttcaatta tttatatgta aaattcctca tcagtaaaaa ataaccgatc
    13381 tcatttctga gaatcggttt tctaaataaa tcaaaccgat catttacata acataaatta
    13441 tgtaaatgat catactacaa caacaaatct ttgacttttc caatttcact ttttggaata
    13501 accaggtgaa tcatatcacc cagatacatt ctggttgagc cgttaactgt ttggctcttg
    13561 ccattatgga cttgagttgt gatgaggacg ttgtgtggta agttgagttc atgaacttgt
    13621 ttcccagcaa ttttatcaga aactggtatt tcgataagtg taacttctcc ttcgctagat
    13681 acttcttctg gaagcatttt ttccagcatg gcttcataga ctggcgtacc tttgagcaaa
    13741 tccatgataa tataagaaac aagagtgaca agaccaagtg gcataaggtt gcgaatatct
    13801 cctaccatct cagttacgag gatcatagcg gttaagggag cttttgatat ggctccaaaa
    13861 tagccactca ttcctagaat gacaaatata gggaattgct cttgactgac aagtccaaga
    13921 ttgacacaga taacaccaac taaggcacca agcaaagaac caagagctaa aatggggagg
    13981 aaaattcctc ctggcagtcc acttccatag ctaatcatac tccaaataaa gcggattaaa
    14041 aagtaagcta ataaaacttg gaaactaaaa ttttgttcag ttaaagaaag gacaagctga
    14101 tttccgccac caatgatttg aggtaagaag attccgactg gtatgataag gataaaagcc
    14161 aagatgggat aataagccct atccaaatgg attttttgac caatcaagtc ataaactctt
    14221 ccaacgttta atacagcttt ctcatagaga aaacctgaaa atccaaggaa aattcccatg
    14281 acgagatata tccaatactg gtctagggtc atgggaggaa tgttatctgg catatccaat
    14341 actggtgtca aaccgaacat gagtagagac acaaagtttg ctacgatgct ggctgctaga
    14401 gttgagaccc agaaaaagcg cgaaaaatgg tgatagactt cttctacaac aaagagaagt
    14461 gctgcaatag gagcattaaa ggctgcggct aaacctgctg cagctccact ggcaatcaag
    14521 gaacgttcct ctactggact ggatttgagc cacttggcaa ttcctttacc accaactgct
    14581 ccaagttgaa tgctgggtcc ctctcgaccc agcatgagtc cactggcaat agcaagaata
    14641 cctagcacat attttttcca aagaatgccc caccagttga gggacatgag gcctttcagt
    14701 tcggcttcga cttgaggaat tcctgagcct ttaatatctt tttctgaccg tgttagtttg
    14761 gcactgagcc aacagatgag tatataaaac aaaaccagta caaaaagatt gcgcactaag
    14821 tacccttgat cttgataaac tccttgtatc aggtggaagc ccttttcaat taagaaacga
    14881 aaggatccga cgataattcc aacgatgagg ccgacaatga ttcctcgacc aacttgggat
    14941 agtatagtgc tggatgcaaa ggcgaattct ttcttagaac ggactatttc cgactgttcc
    15001 tccatggtat ttcctttcaa ttaactttct tttttaccta aaaccagtga tttaacgggt
    15061 tcaaagctgg ttcggtgaat tggggtaact cctagttttg tgaggccttc cagatgttta
    15121 gctgtgccat atcctgcatt agtagcgaaa tcatagccag agaactgctg atcgtattct
    15181 ttcatcaatt catcacgtgt taccttggct actatagatg ctgctgcgat agagagggag
    15241 ttggcatctc ctttgataat ggaggtttgt gaaatgggca agtccagttt catggcatca
    15301 atcaaaaggt gctctggttg agggctgagc tgggagattg cttcttgcat ggctagtttg
    15361 gttgcttcat agatgttgac ttggtcgatg acctgattat ctatgatacc aattccaatc
    15421 gacaaggctt ggtcttgaac ggcttggaaa atctccagat gtttcttttt aggaattttc
    15481 ttgctgtcgt tgagaccttt aatcttacaa tttttaggta aaataacggc cgcagcgact
    15541 acaggaccag caagaggacc acgaccaacc tcatcaatac ctgcaattaa ggtcaatcct
    15601 tgcttataaa gttctttttc ataagaaagc atggattcca agcgcaaatt ttcatctaat
    15661 tcagcttgaa tggctctttt acgcttgctg atttcctttt gaactcctga gcgattatcc
    15721 ttttcaagct ctaaaaaaat agggctttct aactccttga ctgtcacaag gagttctttg
    15781 atttctttaa tcgttgccat cgaggtcttc caatgtatct aaggtatagt taccgagttt
    15841 gccatcacgg acttccttca cgaagagact gtaaaaacgg tcatagtcat cacggaaacc
    15901 gagggcgcgg gtcatatcca taataatcac aggcgcttct tcttcaattt tcatttgttt
    15961 gaagcgttca gccagctttt ctggataatg ttctttgaaa taattgatac caaaaatggt
    16021 aacctcatcc ataggaagca actgatcctt gatagctcca gtcaatgcca acttaagtgc
    16081 aacagtttca tcctcaaact taggccagag aatccccggt gtatccaaga tttccagatc
    16141 tttattggtt ttaagccatt gttgaccttt tgtgacccct ggcttgtttc caacaacagc
    16201 aatcttttta ccagccaaac ggttcatcag agttgattta ccagcgtttg gaatcccaat
    16261 aatcatggta cgcaaggttt caatctgaat cccacgttct ttctggcgag caatcttatc
    16321 agccatgagc ttcttggccg catctgttac aacttttaca gtcacttgct ctttggagtt
    16381 gatagctagc gtctggattc cttgtgattc aaaatactga cgccattcct tggtcattgc
    16441 tggatcagcc aagtcggcct tgtttaaaat caagagtttt ggtttatcac caacaatctt
    16501 ggtcaacata ggattttgac tagatagagg caagcgtgca tctactaaaa tcgtcacaaa
    16561 atcaacaaat tttaaatttt cctgcacctg tcgacgcgct ttagacatgt gaccaggaaa
    16621 ccattgaata gtagccattg agtttttttc ctttcatagc aagggtttag agcccctatt
    16681 ttattttact attgtctaaa caccaagcga acaccaaaac taccatgcaa tggaaaaacc
    16741 tctgatttga ttctcacttg atttcacaat ctttatatca aactgtgggt ggtatttgac
    16801 aatatctttt ttgattttta atagtaaatt cgaaataata tttttaggtg agtaacgtgg
    16861 actaagatgt aacaagtctt tgaactcatc gacactaaat tctactttat tgctattatc
    16921 actagtttca atgaattttt caattattct ggaatattta caggtataac ttttcaattc
    16981 ttcaaaatgg aaattgtgat tttctacaaa ttgatttaag gcttttacag tattttcttg
    17041 tgaacgattt atattatgtg tatagcccat tgttgtctca aagttagcgt gtcctactct
    17101 agtcataata tctttcactg ctatgtgcat ctcattactt tgaaggtaac taatatgcat
    17161 atgcctaaac gaatggggag taacatgttt tacccactta aaaccatagt cacttaaaca
    17221 atttgtcaat aattttcctt ctattcgttt caaaatttga cgaaaagtgc ttgatgttat
    17281 tggagagccg tattctgttc taaatacact ttcagaatgt gtaaaagcag gacagggatg
    17341 tttctccata taagcatcaa actctttatt tctctgtatt gtccttttaa tagcttcgct
    17401 tgcagcttca ggcaaagcta cttctctaat tgaattgagt gttttagttg tatcaaagtg
    17461 aaattgttca acttttaaac aatgatattg aagtgcctta tcaatatgca agattccttt
    17521 ttcaaaatca atatctgatg gtaaaaatgc tgcttcacta attcgaatac ctgtaagcaa
    17581 caatactata gcaagatcat aatagtttgc atttctgcat tggcttaata catcaaaaaa
    17641 tgcgtgtaat tcatggattt ctagaaattt agaatcatgt ctttcttttg ctttacgcct
    17701 tttctctagt gaaatatcta gttttaccgc agtcatagga gagaacttaa tgacattata
    17761 taacacacca tgattaaaaa tcttattaca agtacttttt atatgagtca ttgttgaagg
    17821 tgatgcatca tatatttcta aatatttatt gagacttttt ttcatcagaa gtggagtaat
    17881 cctgtctaat aaaaaatcat ctcctataat tttcccaaga cgcttcatca ccagtagttc
    17941 tctctgaatt gtttgtggtt taacagagac acaccaagtc tgaaaccaat tttcttttaa
    18001 ctctccaaat gttgtaatca gttcagggct aaactgactt tcaaatgaag tagttagtct
    18061 atctatctta tcaagaacct ctctttcagc ttgtttcctc gccctactag tattcttagt
    18121 ataacttaca gttactgatt tccactttcc tgttagtgga tctttgtact tttcaaccac
    18181 ttgatataag ggttgccctt ttgaatttgt tttagttaca taatacataa tttaattcct
    18241 cttaactctt aaaaagaaat aaatcattgt tgtatagaat aaataactac cctatattat
    18301 accatgactt ccttattttg tccgcttttg cttccatctt aagaaacttt caaatccttc
    18361 tagattaatg aaaacaagtt tatgggttgg gttaattaca tacatggaaa atgttctgtt
    18421 ttctcgcatt tctttaatcc atctgttcaa tgtatattga tttaaaccat cccatctttt
    18481 tagaattcct ttcttatcgg cccattctgc aatggaattt tcgacagata tatattttat
    18541 attcatgtca tcatccttcc taaaaaatat tttcacctcc atggcatgac tgatgaagtc
    18601 atcataagaa tttcacttgc tgctctttta cggtggcagc ctgaacggtc agaagtatca
    18661 ttgtatatca tttgtatcat ggcatataaa gtatcgctct attttattga tggttttaat
    18721 atcgctctta tcatggcgag ccattcaaaa ctgctccaca aatgaggaaa gtaccatttt
    18781 ggactattca attgtcaatg tgctttctta acctactact ttttggagta atggtcttct
    18841 ttattatcca ctcgacctac aaggtagtct agactcacct tataaaaatc tgcaagtttg
    18901 ataaggtcat ttatagagat tagcctgcta ccagcttcca ttttagaata agatgatctt
    18961 gtacaattca aaacgatttt cgcaatatat tcttgtgtca aatcatcatc ttcacgtaaa
    19021 tctctaatcc ttttcaacat ttgttgtctc ctaaaacaag tataatatag ttattttctt
    19081 atttttaaat atgtgacaaa ttggcacatg aaactattct atatatactt tttaggaaac
    19141 tgtttactct aaatgtatct cattttcctt aatagatttc gtattttgtt ttttcttata
    19201 tttctttatt gttttattaa acatttcaaa taaatttatt gcttctctat gttgttcctt
    19261 cagtgtttca atctttcctt tatatatgta taaatccttc tctattgtat ctactgaact
    19321 tttaccttga atactatttt ctaaattgct agaactattt gtcgcatcat tcaacaatac
    19381 ttcttctaaa ttactcaaat catcaatttt attttgaacg tggtcaatca tattctctag
    19441 atatgatatt tgggcaatga aatccttggt tatatcttca aaagcattct gactattttc
    19501 tgcagataca agaaaatcta attgttctat tttttcttta attttgctaa gaggaattct
    19561 tctatacata tactgcggtt catactgaag attaaattgc ctaatcaaag ttttaccttt
    19621 cataaagcga tttttttctg ttgaatcttt atgatataca tagtaagaac tagtttctct
    19681 gagaaatact ttaacttttt cttcttccat attgatttga atatttggta caaaaataag
    19741 tccttcttgt cggataccaa actgtacctt aatgtaaatt ccatcgtcta ctacttcttc
    19801 tatttgatta agattcaact ctacttcaaa ctcatgaact gcatccctat ttctcttgaa
    19861 atcttgatag gatttccata ccacctcttc tgtcggcaac tctttttctt taattagctt
    19921 ttcttcattg taaagttcaa ctaaattttt attatctaag acaacagttt catttttgtt
    19981 attaaaatag ttttgaaaat aactaacact ataccgatta gcttttacca attcctgctc
    20041 tgaaatctta atctcatcaa attcaaattg aacatgtttt tctttcggaa ttatttttaa
    20101 tccaaaaaat tctgctcgtt gaatcaattc attcatattc ttcattttcg gaagtaaaaa
    20161 ttctaagata tttatgattt ccctttgaac aaactttttc ttaaaataag tttcattata
    20221 aggttgtttt ctactcaatt tactatcacg tacgacttgt ttcatatttg aatcagtcat
    20281 aaaaaaagta acatgcttgt gtctaaaatc aattttcaaa tgtaaagctt ttgctttttt
    20341 cttgaaatct tcaaaatttt tcgagttctc gattagaaaa tatactcgtt gttttatttc
    20401 atatttgtaa tttgttttgc gataaacttc atactgacga tgcgaataac gattttctat
    20461 aatttttgcc cctgcaattt ttgaaagacg atcagaaacc attcgtagat tacgttctga
    20521 cttataatcc catagaaact ttttatcaga attctgatca attgaattta ggatgatgtg
    20581 attgtggata tgatctttat ccatatgagt tgctacgata aaacgaaatc tacctcctgt
    20641 caactcttta actgtctcat aaccaatctg attgatttgt tcgggagtga ggtggtcatc
    20701 tggagaaaag gactgaatga tgtgatgaga atgaattttt cgttgattta cttctcgcct
    20761 atcatgacga aattcataaa gagtatcatt acttaaaaaa ttatcattgt acatcttcac
    20821 tagttcttca taactaggaa aatctaaata atttctcatt ccaaaatctg aaactagtgt
    20881 taggtttttt gttttacttg gattcaaaat atatttgatt agtttactac gataattttt
    20941 tccatgaatc gcaaagtgtt tagtgatgac cataaaattt cctcaatttt tcagattgaa
    21001 taagaaaatc tttctccact tctactatta actcttctat accttttctc aactcattta
    21061 attcaacttc cgttattaaa ttagaataat ttatgctcct agctatttga ttaatattat
    21121 ttcctattcg ttttaattca aaaatcaaat cttgataact atttgtatca atggtgataa
    21181 aattcatacc aggatctagt agagttcgtc tagcatattc tgagaacgat aagcagttac
    21241 tttttgagat attttcattc aatttgacta attctaggtc agataaaaag acctttttta
    21301 aatttgttct atatcggtgc tccactctac tacctcatgt atttgttacg aaaatcttca
    21361 ctaagaggac ctgttttttc tacctcttta attaattcct gaatacaagt taacaaaata
    21421 gaaacatgtt cgtgagtaac ctgatgattt gttttagcaa ttatgaatac ttcatgaaca
    21481 tcacggctaa tttgttccaa cttttgtttt ttccaaaggt tgaaccattt ttccatctgt
    21541 ttttgtccat cagataatag taagctttta cggagaaaat cagaaaaatt atcctctcct
    21601 ttctctctca ttaaatctag tatttgtttt tcttccgttt ctgttaagcg aaattgtttc
    21661 cgaatactac gtatatctct tttcatatga tttatcctct ctcatagata cttgtactga
    21721 caatgtaagc ttacagacac tgtcagtacg ttttacaaaa tagattcaac atttttgtaa
    21781 ggctttgcga gctcagatat tgtgtccaca atatcccaaa aatcatatcg cctgccattt
    21841 caaacctcac ggttcaaaaa acaaacgata tgacaatgtg gtggctccgc ccccaaaccc
    21901 ccaagataaa tctaaattaa aaaaagtata acaaatactt tttgataaaa ttatcacaga
    21961 aaaaagagcc ctgtcggact cttacaaatt aaaacaatgt ctctgatatt catactgtct
    22021 aataccacta ctgtctttgt tcatcttgat agaaaaaaca aagtaatgat cacgaccgtc
    22081 taaagattta cttttgttaa gtttaaaata atgtttttga gacatagcca ttgtgcgtaa
    22141 aatatcatct gtgataaatg ttaatggtat atctaaagct gaatacttgt aaaaatctga
    22201 ctcaaactgt aaataagaat ctgaaaaata atctagctgt aatttatcat catataattc
    22261 tttacgattc atgtaattcc tccccttcta tctgtatatc gagtatatct tcccatttta
    22321 atcgaagaaa accagtgtct gattttatag atataaactc ttttccaatc tctttaacaa
    22381 tacctgatac tacttttctt tgattagaaa acttaaaaac aaaagttgca gggaatacat
    22441 tcgtataaag ttgacgaaca aatagaactt tctcttccaa tgatagggaa atggagatat
    22501 cttctttatt tttttctgcc caaagagaac tggaatgttc tgataaaaag aagcccatcc
    22561 acttagccat gccacgatcc tgatatactc gggcagactc aaaaggtaaa taagaacgat
    22621 tcatcatttt agtccatcta atcctccagc tgaatgacca ccaatgagtt tgcttctagc
    22681 aattgttcta gaagcttgat ctagggcatt acctttcaat agtgaagtga atccaaattc
    22741 tgttcgaata gcatcgattg cggactggag cctttcttct ttttctattt tctcaatatc
    22801 atcaaataat gaaatcaatc caaaggattc atccactaaa ccagaatagt taaccgcaac
    22861 attcctgata gctcctgaag tatatttagt gtgaaataac tttaaaacgt agtttgtcag
    22921 tagtgctgtt tgattagttg gttcaatttt catttgagta ttgatagaac gcttttgttc
    22981 cactttagag tagcctagat gtatagaaac tactgttgct tttttaccag atcttctcaa
    23041 tctaactgca acttgttctg ccatctcacg aagtatgatc tcaatatctc tttgtttaat
    23101 ataatctttt ggtaaaactt gagagttccc tatccctttt gactttggct tataaggttt
    23161 atgaacgttg ctttcgtcaa tcccattggc atgaaaccat aactctagtc ccataatccc
    23221 aagctctttt ttaatcaagt caggattagc ctgagccaat tctttaatcg aaaagatacc
    23281 taaattatgt aatcttttct ccgtgcgatt tccaattccc cagaaatctg tcattttagg
    23341 aatagtccat actttctttt cgacatcctc ataggaccaa ttggctctca ttgtcggagt
    23401 ctttttagct tcattatcaa gtgccaactt agctaataag ggattggcat tagacatacc
    23461 taccgttgaa tagattcctg tttttctcca aatctttttt tgaatggccg ccgaaataat
    23521 atctaactta tcttttcgac taatcctttt atcaggcaca aaataattta atgaactggt
    23581 taaatcaata aatccttcat caattgaata gggataaata tcgtctggag ccgcaaattc
    23641 ttgaaaaatt ttttgaatct ccatattgac tgcaatataa gtatccattc tcggaggaac
    23701 aatcacagtt gattttgccc attcctctat ataacgaaca taatctatcg ttgtcggtaa
    23761 accttgcttt ctagcattat aataagagaa tttgcgagtc tttacatcaa aaggtaaatc
    23821 ataggaacgt ccaacgttcg actttccaaa gaccttttta aacataggag aggaagcaag
    23881 aattaaacca gcagaattat ctgcacgact cataacacaa agcgaagtct taagtgggtg
    23941 taatcctcta tctacacatt ctacacttgc gtaaaaagat ttcatatcaa taaaggcaat
    24001 gtcactttga ggttcgagac tataatcaaa ccaactcata cttagtcctc taaaggcata
    24061 aagttcccaa ctattttccc tataatgcga ggattctcat cataaggcgc aaacttatct
    24121 ggatagttcc gattgagtga aactaatcta agcccatttt cttcacgata aactttcttg
    24181 ataaaggttt gactgtccca atctatcgca tagatagccc cgtcatagtc aaatcctgtt
    24241 tgcttaataa gggctacaga accattttta taagttggtt ccatagaaac accagatacc
    24301 cacgatgcaa agtcataatc aaattgacga ttaaaataaa ctgtatcgta attaccatca
    24361 tcaaagtaag ctgttcccgt accagctgat aatttttcat aaaccttata agcaaaacgc
    24421 tcaggaattt ctacaacctt cgcattctgt ttgttcaaca attctgtagc ataatgaagt
    24481 gttgcttttt gattcttttt agttagcttg agataggttt ctactatttc aaactctgat
    24541 tcaaaatatc gagggtctac attaaaaatc tcactcaatt tgcttagatt attttgattc
    24601 ggttttgttt tacctgattc ccaattaaag tatgaagctc tactaattcc taaactagaa
    24661 gcaagttgag attgagataa gccttgactc tctctttttt cttttaattt agtaggtgaa
    24721 aacatctctt ctcctttgta agtttattaa ctaacaaaag agtaccatag cttcttgaaa
    24781 aaatcaagag tttaataaca ccctggattt aaaataatca taaactacaa gaaatcatca
    24841 ctgaagaatg ctaaaacttt tgaaaaaatt tgaagaagaa aatagagaat ataaaaaagg
    24901 atcgttattt tttaattgac gatccaatag actttatttt aaaaatctaa ctctacaaac
    24961 catttcgatt agttaaatct ttcaatcttt cttctccaga tttaagcatc tctttctcca
    25021 cttgattcca ttctccaaat agtaaatcat gaagaacggt tgctgctgaa gttgtatttt
    25081 cttttgaatc atatacacaa cttctatctc gttgataaat ttgaattctt tcaaaaatag
    25141 ctagttcttc caattgccgt gtattatcaa ctagatgatt tacaatgaaa tcatgatgtt
    25201 cttttgaagt tgcgcgtgct tgatttggat tgatagagta cagttcttcg tatcggataa
    25261 gagtactcag ataggacaat tcgggcttgg ttgcgattaa agctaattgt acttcatatc
    25321 ccttactttt caagagttgt gctgttttct ttggaacatc aatcgttcgt aaagttccct
    25381 ctatcaaaag attgtatccc aaatgactca attctgttac taaagactct accattttac
    25441 ctgcaaaatc tttggtgtat tctacactat ctttgccata ttcttgctgc agttctaaat
    25501 agcgtggatg ctgagaacga aaactatcac catctatgat aacaatattt ccttgaaatt
    25561 ctttctgttt aatccgatga attgtagttt taccggcacc actttgccct ccaagcaaaa
    25621 tcgctatagg ttgcttactg gacttttttc ctcttgtcag tgaacgaaga ttccgtgtta
    25681 gagcatgttt gaattcacta tcagtataat cttggatttc cattaggcta ccatccgttt
    25741 ttcagatatc tctaacatac gttcaattcc atccaaatag ccgctatacc tctctatttc
    25801 atcaaaagtt tctactaaat agatattcgt
//
LOCUS       DAVBOG010000030        25643 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.030, whole genome shotgun sequence.
ACCESSION   DAVBOG010000030 DAVBOG010000000
VERSION     DAVBOG010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 25643)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25643)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25643
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.030"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..163)
                     /locus_tag="VQ865_001337"
     CDS             complement(<1..163)
                     /locus_tag="VQ865_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3135668.1"
                     /translation="MTIHLSSLGQVYLVCGKTDMRQGIDSLAYLVKTHFELDPFSGQV
                     FLFCGGRKDR"
     gene            complement(144..329)
                     /locus_tag="VQ865_001338"
     CDS             complement(144..329)
                     /locus_tag="VQ865_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001136123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135669.1"
                     /translation="MPQPIVPVEIPQSRPFDSKKRNDILLKIRIGKLEVSFFQSLNLE
                     MVEQLLDKVLLYDNSSI"
     gene            complement(633..2195)
                     /gene="guaA"
                     /locus_tag="VQ865_001339"
     CDS             complement(633..2195)
                     /gene="guaA"
                     /locus_tag="VQ865_001339"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000065723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HET3135670.1"
                     /translation="MSNISTDLQDVEKIIVLDYGSQYNQLISRRIRDIGVFSELKSHK
                     ISAAEVREVNPVGIILSGGPNSVYEDGSFDIDPEIFELGIPILGICYGMQLLTHKLGG
                     KVVPAGDAGNREYGQSTLTHTPSALFESTPDEQTVLMSHGDAVTEIPADFVRTGTSAD
                     CPYAAIENPDKHIYGIQFHPEVRHSVYGNDILRNFALNICKAKGDWSMDNFIDMQIKK
                     IRETVGDKRVLLGLSGGVDSSVVGVLLQKAIGDQLICIFVDHGLLRKGEADQVMDMLG
                     GKFGLNIVKADAAKRFLDKLAGVSDPEQKRKIIGNEFVYVFDDEASKLKDVKFLAQGT
                     LYTDVIESGTDTAQTIKSHHNVGGLPEDMQFELIEPLNTLYKDEVRALGTELGMPDHI
                     VWRQPFPGPGLAIRVMGEITEEKLETVRESDAILREEIAKAGLDRDIWQYFTVNTGVR
                     SVGVMGDGRTYDYTIAIRAITSIDGMTADFAKIPWEVLQKISVRIVNEVDHVNRIVYD
                     ITSKPPATVEWE"
     gene            2337..3035
                     /locus_tag="VQ865_001340"
     CDS             2337..3035
                     /locus_tag="VQ865_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000936186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3135671.1"
                     /translation="MLPAYMKIHDQIKKDIDEHRWAIGERLPSERDLAEQFAVSRMTL
                     RQAVSLLVEEGVLERHVGSGTFVSSTRVQEKMRGTTSFTEIVKSQGKVPSSQLISYKK
                     TIPNEQEVAKLGIFPTDNIIRMERVRYADQVPLVYEVASIPEKFIKDFKKEEITSHFF
                     QTLQKHGYRIGKSQQTIYARLAKEKIAHYLEVEKGHAILGLTQVSYLEDGTAFEYVKS
                     QYVGERFEFYLENN"
     gene            complement(3078..3974)
                     /locus_tag="VQ865_001341"
     CDS             complement(3078..3974)
                     /locus_tag="VQ865_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter"
                     /protein_id="HET3135672.1"
                     /translation="MSNSLKGTLLTVVAGIAWGLSGTSGQYLMAHGISALVLTNLRLL
                     IAGGILMLLAYATAKDKILVFLKDRKSLLSLLIFALIGLFLNQFAYLSAIQETNAGTA
                     TVLQYVCPVGILIYSCIKDRVAPTLGEIVSIIFAIGGTFLIATHGQLDQLSMTPAGLF
                     WGLFSAFTYALYIILPIALIKKWGSSLVIGVGMVIAGLVALPFTGVLQADIPTSLDFL
                     LAFAGIILIGTVFAYTAFLKGASLIGPVKSSLLASIEPISAIFFAFLIMNEQFYPIDF
                     LGMAMILFAVTLISLKDLFLEK"
     gene            complement(3983..4918)
                     /locus_tag="VQ865_001342"
     CDS             complement(3983..4918)
                     /locus_tag="VQ865_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HET3135673.1"
                     /translation="MKWTKIIKKIEEQIEAGIYPGASFAYFKDNQWTEFYLGQSDPEH
                     GLQTEAGLVYDLASVSKVVGVGTVCTFLWEIGQLDIDRLVIDFLPESDYPDITIRQLL
                     THATDLDPFIPNRDLLTAPELKEAMFHLNRRSQPAFLYSDVHFLLLGFILERIFNQDL
                     DVILKDQVWKPWGMTETKFGSVELAVPTVRGVEAGIVHDPKARLLGRHAGSAGLFSTI
                     KDLQIFLEHYLADDFARDLSQNFSPLDDKERSLAWNLEGDWLDHTGYTGTFIMWNRQK
                     QEATIFLSNRTYEKDERAQWILDRNQVMNLIRKEE"
     gene            complement(4915..5640)
                     /locus_tag="VQ865_001343"
     CDS             complement(4915..5640)
                     /locus_tag="VQ865_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001102210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CppA family protein"
                     /protein_id="HET3135674.1"
                     /translation="MNVNQIVRIIPTLKANNRKLNETFYIETLGMKALLEESAFLSLG
                     DQTGLEKLVLEEAPSMRTRKVEGRKKLARLIVKVENPLEIEGILSKTDSIHRLYKGQN
                     GYAFEIFSPEDDLILIHAEDDRASLVEVGEKPEFQTDLVSISLSKFEISMELHLPTDI
                     ESFLESSEIGASLDFIPAQGQDLTVDNTVTWDLSMLKFLVNELDIASLRQKFESTEYF
                     IPKSEKFFLCKDRNNVELWFEEV"
     gene            complement(5724..6359)
                     /locus_tag="VQ865_001344"
     CDS             complement(5724..6359)
                     /locus_tag="VQ865_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-alkyl-2-acetylglycerophosphocholine esterase"
                     /protein_id="HET3135675.1"
                     /translation="MAVQLLENWLLKEQEKIQTKYRHLNHISVVEPNILFIGDSIVEY
                     YPLQELFGTSKTIVNRGIRGYQTGLLLENLDAHLYGGAVDKIFLLIGTNDIGKDVPVN
                     EALNNLEAIIQSVARDYPLTEIKLLSILPVNEGEEYQQAVYIRSNEKIQNWNQAYQEL
                     ASAYMQVEFVPVFDCLTDQAGQLKKEYTTDGLHLSIAGYQALSKALKDYLY"
     gene            complement(6361..7188)
                     /locus_tag="VQ865_001345"
     CDS             complement(6361..7188)
                     /locus_tag="VQ865_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3135676.1"
                     /translation="MMIKVIATDMDGTLLDARGQLDLPRLEKILDQLDQRGIRFVIAT
                     GNEIHRMRQLLSPLVDRVVLVVANGARIFENNELIQAQTWDDAIVNKALTHFKGRACQ
                     DQFVVTGMKGDFVKEGTIFTDLESFMTPEMIEKFYQRMQFVDELTSDLFGGVLKMSMV
                     VGEERLSSVLEEINALFDGRVRAVSSGYGCIDILQAGIHKAWGLEELLKRWDLKSQEI
                     MAFGDSENDVEMLEMAGIAYAMENADEKAKAVATALAPANSQGGVYQVLENWLEKGE"
     gene            complement(7210..7545)
                     /locus_tag="VQ865_001346"
     CDS             complement(7210..7545)
                     /locus_tag="VQ865_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-gamma-glutamate biosynthesis protein"
                     /protein_id="HET3135677.1"
                     /translation="MGNFISNQRIESMGDEENAKWTERGVLMDVTIKKKDGKTTIGTA
                     KAHPTWVNRTPKGTFSPEGYPLYHYQTYILEDFIEDGSHRDQLDEATKERIDTAYKEM
                     NEHVGLKWY"
     gene            complement(7546..8077)
                     /locus_tag="VQ865_001347"
                     /pseudo
     CDS             complement(7546..8077)
                     /locus_tag="VQ865_001347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864593.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="CapA family protein"
     gene            8708..9319
                     /locus_tag="VQ865_001348"
     CDS             8708..9319
                     /locus_tag="VQ865_001348"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015058782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HET3135678.1"
                     /translation="MSAIERITKAAHLIDMNDIIREGNPTLRAIAEEVTFPLSDQEII
                     LGEKMMQFLKHSQDPVMAEKMGLRGGVGLAAPQLDISKRIIAVLVPNIVEEGETPQEA
                     YDLEAIMYNPKIVSHSVQDAALGEGEGCLSVDRNVPGYVVRHARVTVDYFDKDGEKHR
                     IKLKGYNSIVVQHEIDHINGIMFYDRINEKDPFAVKDGLLILE"
     gene            9364..10092
                     /gene="rlmB"
                     /locus_tag="VQ865_001349"
     CDS             9364..10092
                     /gene="rlmB"
                     /locus_tag="VQ865_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HET3135679.1"
                     /translation="MKTNDIVYGVHAVTEALLANTGNKLYLQEDLRGKNVEKVKELAT
                     EKKVSISWTSKKSLSEITEGAVHQGFVLRVSEFAYSELDYILAKTRQEENPLLLILDG
                     LTDPHNLGSILRTADATNVSGVIIPKHRAVGVTPVVAKTATGAIEHVPIARVTNLSQT
                     LDKLKDEGFWTFGTDMNGTPCHKWNTKGKIALIIGNEGKGISSNIKKQVDEMITIPMN
                     GHVQSLNASVAAAILMYEVFLNRL"
     gene            complement(10131..11042)
                     /gene="trxB"
                     /locus_tag="VQ865_001350"
     CDS             complement(10131..11042)
                     /gene="trxB"
                     /locus_tag="VQ865_001350"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HET3135680.1"
                     /translation="MYDTIIIGAGPAGMTAALYAARSNLKVALIEGGLPGGQMNNTSD
                     IENYPGYANISGPELAEKMFEPLENLGVEHIYGYVENVEDHGDFKKVMTDDQTYETRT
                     VIVATGSKHRPLGVPGEEELNSRGVSYCAVCDGAFFRDQDLLVVGGGDSAVEEALFLT
                     RFAKTVTIVHRRDQLRAQKVLQDRAFANEKISFIWDSVVKEIKGENRVESVVFENVKT
                     GQVTEQAFGGVFIYVGLDPLSDFVKELNIQDQAGWIVTDSHMKTAVDGIFAVGDVRLK
                     DLRQVTTAVGDGAIAGQEAYKFITEHS"
     gene            complement(11108..11332)
                     /locus_tag="VQ865_001351"
     CDS             complement(11108..11332)
                     /locus_tag="VQ865_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000924294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4059 family protein"
                     /protein_id="HET3135681.1"
                     /translation="MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQ
                     AHLYDMIMIGVLVVPVLSFAVMSLILVFKA"
     gene            complement(11410..12153)
                     /locus_tag="VQ865_001352"
     CDS             complement(11410..12153)
                     /locus_tag="VQ865_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3135682.1"
                     /translation="MIKISNLSKSFSGQTVLDHLNLDIQKGEVVALIGSSGAGKSTFL
                     RSLNYLETPDSGSIQIDGFSVDFSKITQEEILALRRKLSMVFQQFNLFERRTALDNVK
                     EGLVVVKKLSDQEATKIAKEELAKVGLSDRENHYPRHLSGGQKQRVALARALAMKPDV
                     LLLDEPTSALDPELVGEVEKSIADAAKSGQTMILVSHDMSFVAQVADKILFLDKGKII
                     ESGTPDEIIHTPKEERTKEFFASYKRTYI"
     gene            complement(12153..12953)
                     /locus_tag="VQ865_001353"
     CDS             complement(12153..12953)
                     /locus_tag="VQ865_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001103446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3135683.1"
                     /translation="MNVTTILASDWYQNLMQLIPDGKLFSLRSVFDGIPRIVQQLPTT
                     IMLTIGGALFGLVLALLFAIVKINRVKILYPLQAFFVSFLKGTPILVQLMLTYYGIPL
                     ALKALNQQWGTGLNINAIPAAAFAIVAFAFNEAAYASETIRAAILSVNPGEIEAARSL
                     GMTRAQVYRRVIIPNAAVVATPTLINSLIGLTKGTSLAFSAGVVEVFAQAQILGGADY
                     RYFERFISVALVYWVVNIGIESLGRFIERKMAISAPDTVQTDVKGDLR"
     gene            complement(13111..13467)
                     /locus_tag="VQ865_001354"
     CDS             complement(13111..13467)
                     /locus_tag="VQ865_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HET3135684.1"
                     /translation="MLEFIEYPKCSTCKKAKQELNQLGVDYKAVHIVEETPSQEVILN
                     WLETSGFELKQFFNTSGIKYRELGLKDKVGSLSNQEAAELLASDGMLLKRPILVENGT
                     VKQIGYRKSYEELGLK"
     gene            complement(13480..13992)
                     /locus_tag="VQ865_001355"
     CDS             complement(13480..13992)
                     /locus_tag="VQ865_001355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001170346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HET3135685.1"
                     /translation="MQKKYVKILYSSPIGILSLVADDHYLYGIWVQEQKHFERGLGDE
                     TIEEVVSHPILDPVIACLDDYFKGKPQDLSNLLLAPIGTNFEKRVWDYLQGIPYGQTV
                     TYGQIAQDLQVASAQAIGGAVGRNPWSILVPCHRVLGAGKRLTGYAAGVEKKAWLLEH
                     EGVDFKDINK"
     gene            complement(13992..14486)
                     /locus_tag="VQ865_001356"
     CDS             complement(13992..14486)
                     /locus_tag="VQ865_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135686.1"
                     /translation="MEIRLAFPNEVDAIMQVIEDAKKCLADAGSNQWQNGYPNADVII
                     DDIISGQAYVALEEGELLAYAAVTKSPEEAYEAIYEGNWQAGESEYLVFHRIAVAADV
                     QGKGVAQTFLEGLIEGFDYLDFRSDTHAENKVMQHIFEKLGFKQVGKVPVDGERLAYQ
                     KLKK"
     gene            14621..15067
                     /locus_tag="VQ865_001357"
     CDS             14621..15067
                     /locus_tag="VQ865_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HET3135687.1"
                     /translation="MKTTFSYPKWAEIPNINLYLDQVLLYVNQVCAPISPNKDKGLTA
                     SMVNNYVKNGYLTKPDKKKYQRQQIARLIAITTLKSVFSIQEIAQTLNTLQTQASSDQ
                     LYDAFVDYMNQGIDPANPIIQTSCQTVKLYHQTLDLIDHTQEEVIQ"
     gene            15064..15711
                     /locus_tag="VQ865_001358"
     CDS             15064..15711
                     /locus_tag="VQ865_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HET3135688.1"
                     /translation="MNTSLKLSKQLSFGEEIANSVTHAVGAVIMLILLPISSIYSYEA
                     HGFLSSIGVSIFVISLFLMFLSSTIYHSMAYGSTHKYVLRIIDHSMIYVAIAGSYTPV
                     VLTLMNNWFGYLIIVIQWGTTIFGILYKIFAKKVNEKFSLALYLIMGWLVLAIIPAII
                     SQTTPVFWSLMVTGGLCYTVGAGFYAKKKPYFHMIWHLFILAASALQYIAIVYYM"
     gene            complement(15732..16313)
                     /gene="pdxT"
                     /locus_tag="VQ865_001359"
     CDS             complement(15732..16313)
                     /gene="pdxT"
                     /locus_tag="VQ865_001359"
                     /EC_number="3.5.1.2"
                     /EC_number="4.3.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000689933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase glutaminase
                     subunit PdxT"
                     /protein_id="HET3135689.1"
                     /translation="MKIGILALQGAFAEHAKVLDQLGVESVELRNLDDFQQDQSDLSG
                     LILPGGESTTMGKLLRDQNMLLPIREAILSGLPVFGTCAGLILLAKEITSQKESHLGT
                     MDMVVERNAYGRQLGSFYTEAECKGVGKIPMTFIRGPIISSVGEGVEILATVNNQIVA
                     AQEKNMLVSSFHPELTDDVRLHQYFINMCKEKS"
     gene            complement(16314..17189)
                     /gene="pdxS"
                     /locus_tag="VQ865_001360"
     CDS             complement(16314..17189)
                     /gene="pdxS"
                     /locus_tag="VQ865_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012054698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal 5'-phosphate synthase lyase subunit
                     PdxS"
                     /protein_id="HET3135690.1"
                     /translation="MTENRYELNKNLAQMLKGGVIMDVQNPEQARIAEAAGAAAVMAL
                     ERIPADIRAAGGVSRMSDPKMIKEIQEAVSIPVMAKVRIGHFVEAQILEAIEIDYIDE
                     SEVLSPADDRFHVDKKEFQVPFVCGAKDLGEALRRIAEGASMIRTKGEPGTGDIVQAV
                     RHMRMMNQEIRRIQNLREDELYVAAKDLQVPVELVQYVHEHGKLPVVNFAAGGVATPA
                     DAALMMQLGAEGVFVGSGIFKSGDPVKRASAIVKAVTNFRNPQILAQISEDLGEAMVG
                     INENEIQILMAERGK"
     gene            complement(17341..18720)
                     /locus_tag="VQ865_001361"
     CDS             complement(17341..18720)
                     /locus_tag="VQ865_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HET3135691.1"
                     /translation="MSKIVVVGANHAGTACINTMLDNFGNENEIVVFDQNSNISFLGC
                     GMALWIGEQIDGAEGLFYSDKEKLEAKGAKVYMNSPVLSIDYDNKVVTAEVEGKEHKE
                     SYEKLIFATGSTPILPPIEGVEIVKGNREFKATLENVQFVKLYQNAEEVINKLSDKSQ
                     HLDRIAVVGGGYIGVELAEAFERLGKEVVLVDIVDTVLNGYYDKDFTQMMAKNLEDHN
                     IRLALGQTVKAIEGDGKVERLITDKESFDVDMVILAVGFRPNTALADGKIELFRNGAF
                     LVDKKQETSIPGVYAVGDCATVYDNARKDTSYIALASNAVRTGIVGAYNACGHELEGI
                     GVQGSNGISIYGLHMVSTGLTLEKAKAAGYNATETGFNDLQKPEFMKHDNHEVAIKIV
                     FDKDSREILGAQMVSHDIAISMGIHMFSLAIQEHVTIDKLALTDLFFLPHFNKPYNYI
                     TMAALTAEK"
     gene            19014..19937
                     /locus_tag="VQ865_001362"
     CDS             19014..19937
                     /locus_tag="VQ865_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000175414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HET3135692.1"
                     /translation="MTLRSHSERLMGTTITISLVDEQADIFLQKSFDLLKELEYRFNA
                     NSQESELMEINYQAGIAPVTVHPDLFELISLGLEHSLALSSHLNISIGPLIQTWRIGF
                     SDAKVAQPQEIESVLPLINPHGIELDSSTSTVFLKQKGMKIDLGCLAKGYSADKVAQF
                     LRKEGVTSALINLGGNILTIGKNQARGDNPWQIGIQDPANPRGNHLMTIPVVNKSVVT
                     SGIYERHLTVDGQDYHHIFDSQTGYPVETELASLTIISDKSVDGEIWTTRLFGERPAS
                     ILWQVESLEGIEVILIDKEGHLSCSSGIPTL"
     gene            19997..20602
                     /locus_tag="VQ865_001363"
     CDS             19997..20602
                     /locus_tag="VQ865_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3135693.1"
                     /translation="MLKLIAIVGTNSKRSTNRQLLQYMQKHFSDKAEIELVEIKAIPV
                     FNKPADKQVPAEILEIAAKIEEADGVIIGTPEYDHSIPAVLMSALAWLSYGIYPLLNK
                     PIMITGASYGTLGSSRAQLQLRQILNAPEIKANVLPDEFLLSHSLQAFNPSGDLVDLD
                     VIKKLDAIFDDFRIFVKITEKLRNAQELLRKDAEDFDWENL"
     gene            20621..21865
                     /locus_tag="VQ865_001364"
     CDS             20621..21865
                     /locus_tag="VQ865_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000673688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HET3135694.1"
                     /translation="MKFVGLVGSNYDQSYNRKLLEFIRRYFKLKFELEVLEIDEVPMF
                     NQDEKWDESFQLRYLYNKITRADGVIIATPEHNHTISASLKSVLEWLSYEVHPFENKP
                     VMIVGASYYDQGTSRAQVHLRKILDAPGVNAYTLPGNEFLLGKAKEAFDNNGNITNEG
                     TVKFLETCLDNFVKYVGVVSKLKKPKPIESEDLDCGKPIATTITEVDPDDPEWVEKVA
                     AITGAVSGDTYVKLDHGILTVNQIDMFLKAMPFELTYADDNNQFLYYNNAHQDPDTMF
                     AKRVPPQSGSRMSTVHGSLPPARMKNVEWVIGTLRNGNQEYVRTIVPGSPAGVINTHN
                     YQAMYYPDGSYAGINEIVFNFQPWLDWYLKETGQRLVGGSGPFAPAAGGHGDADATSG
                     ASDSGDAGGHGGDADATAGASY"
     gene            complement(22088..22345)
                     /locus_tag="VQ865_001365"
     CDS             complement(22088..22345)
                     /locus_tag="VQ865_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002983550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HET3135695.1"
                     /translation="MDPKKIARINELAKKKKTEGLTSEEKVEQAKLREEYIEGYRRAV
                     RHHIEGIKIVDEEGNDVTPEKLRQVQREKGLHGRSLDDPNS"
     gene            complement(22387..24423)
                     /locus_tag="VQ865_001366"
     CDS             complement(22387..24423)
                     /locus_tag="VQ865_001366"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HET3135696.1"
                     /translation="MTKNLLVELGLEELPAYVVTPSEKQLGEKMAAFLKENRLSFEAI
                     QTFSTPRRLAVRVTGLSDKQSDLTEDFKGPAKKIALDSDGNFTKAAQGFVRGKGLTVE
                     DIEFREIKGEEYVYVTKEEVGQAVEAIVPGVVDVLKSLTFPVSMHWAGNSFEYIRPVH
                     TLTVLLDEQEFDLDFLDIKGSRVSRGHRFLGKETKIQSALSYEEDLRKQFVIADPCER
                     EQMIVDQIKEIEAKHGVRIEIDADLLNEVLNLVEYPTAFMGSFDAKYLEVPEEVLVTS
                     MKEHQRYFVVRDQDGKLLPNFISVRNGNAERLKNVIKGNEKVLVARLEDGEFFWREDQ
                     KLVISDLVEKLNNVTFHEKIGSLREHMIRTGQITVLLAEKAGLSVDETVDLARAAAIY
                     KFDLLTGMVGEFDELQGIMGEKYTLLAGETPAVAAAIREHYMPTSAEGELPESKVGAV
                     LAIADKLDTILSFFSVGLIPSGSNDPYALRRATQGVVRILDAFGWHIAMDELIDSLYA
                     LKFDSLTYENKAEVMDFIKARVDKMMGSTPKDIKEAVLAGSNFVVADMLEAASALVEV
                     SKEEYFKPSVESLSRAFNLAEKAEGVATVDSALFENDQEKALAEAVETLVLSGPASQQ
                     LKQLFALSPVIDAFFENTMVMAEDQAVRQNRLAILSQLTKKAAKFACFNQINTK"
     gene            complement(24683..25600)
                     /gene="glyQ"
                     /locus_tag="VQ865_001367"
     CDS             complement(24683..25600)
                     /gene="glyQ"
                     /locus_tag="VQ865_001367"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018163989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HET3135697.1"
                     /translation="MSKKLTFQEIILTLQQFWNDQGCMLMQAYDNEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPSNIQELYLESLEK
                     LGINPLEHDIRFVEDNWENPSTGSAGLGWEVWLDGMEITQFTYFQQVGGLATGPVTAE
                     VTYGLERLASYIQEVDSVYDIEWADGVKYGEIFIQPEYEHSKYSFEISDQEILLENFD
                     KFEKEAGRALEEGLVHPAYDYVLKCSHTFNLLDARGAVSVTERAGYIARIRNLARVVA
                     KTFVAERKRLGYPLLDEETRVKLLAEDAE"
BASE COUNT         7597 a         5769 c         4668 g         7609 t
ORIGIN      
        1 agcggtcttt acgtccacca caaaagagaa aaacttgacc ggagaaagga tctaattcaa
       61 agtgggtttt aaccagataa gccagtgaat caatgccttg cctcatatcc gttttcccac
      121 atacgagata gacctgccct aggctagata gatgaattgt catagagcaa caccttatcc
      181 aaaagctgtt ctaccatttc gagattgaga gattgaaaaa aacttacttc aagcttgcca
      241 atacgaattt taagcagaat atcatttctc tttttagaat caaaaggacg agattgtgga
      301 atctctacag gaacaatagg ttgtggcatt aaaatatcct ccaatagttt tactttacta
      361 atagtataca ggaggagctc catgaatgat agataccttg ttatgacgcg cttaccatat
      421 tagaaagttg gctctctaat taaattaatt ctcattatat atatcaaaag accgcagttt
      481 gaaaactacg gtctaatttt ttgtccaaat gtaaaccact tggaactatt attcaattta
      541 ttctttttag caaatgttcc cgttttaatc ccagttacag tttttaatcc tttgtaaccg
      601 ttgattttac aaagctttta atttttttgc gattactccc actcaactgt tgcaggtggt
      661 ttacttgtaa tatcgtagac gatacggtta acatgatcca cttcatttac gatacgtact
      721 gagatttttt gaagtacttc ccatggaatt ttggcaaaat cagcagtcat accatcgata
      781 gaagtgatag cacggattgc aatcgtgtag tcatacgtac gaccgtcacc cataacaccg
      841 actgaacgaa cgcctgtgtt aacagtgaag tattgccaaa tatcgcggtc aagtccagct
      901 ttagcgattt cttcacgaag aatagcgtct gattcacgaa cggtttcaag tttctcttca
      961 gtgatttcac ccatgacacg gatagcaagt cctggtcctg ggaatggttg gcgccatacg
     1021 atatggtctg gcataccaag ctctgtacca agagcacgaa cttcatcctt gtaaagagta
     1081 ttgagtggtt caatcaattc aaactgcata tcttctggaa gaccacccac gttgtggtgt
     1141 gacttgatag tttgagctgt atccgtacca gactcgataa catctgtata taaagtacct
     1201 tgagcaagga atttcacatc tttgagcttg cttgcttcgt catcgaatac atagacaaac
     1261 tcgttaccga tgattttacg tttttgttca ggatcagaaa cgccagcaag tttgtcaagg
     1321 aaacgtttag cagcgtctgc tttgacgata ttcaaaccaa acttaccacc gagcatgtcc
     1381 ataacttgat cagcttcgcc tttacgaaga agaccgtggt ccacgaagat acagatcaat
     1441 tgatcgccaa tcgctttttg gagaagaacc ccaacgacag atgagtcaac accacctgat
     1501 agaccaagaa ggacacgttt atcaccgacg gtttcacgaa tttttttgat ctgcatgtca
     1561 atgaaattat ccattgacca gtcaccttta gccttacaaa tgttaagggc aaagttacga
     1621 aggatatcat ttccgtatac agaatgacga acttctgggt ggaattggat accgtaaatg
     1681 tgtttatctg ggttttcgat ggctgcgtat gggcagtcag ctgatgtacc tgtacgaaca
     1741 aagtcagcag gaatctcagt aaccgcatca ccatggctca tcaaaacagt ctgttcatca
     1801 ggtgttgatt caaaaagcgc tgatggtgtg tgagttaggg ttgattgacc gtattcacga
     1861 tttccagcat cacctgcagg aacaactttt cctccaagtt tatgggtcaa taactgcata
     1921 ccataacaga ttcccaaaat tggaattccg agttcgaaga tttctgggtc aatatcaaat
     1981 gaaccatctt catatacaga atttggacca cctgatagaa taattcctac aggattgact
     2041 tcacgaactt cagcagctga aattttatgg ctttttagtt ctgaaaaaac accaatatca
     2101 cggatacggc gtgaaatcag ctggttgtac tggctaccat agtccaatac gatgattttt
     2161 tctacatctt gcaaatcagt tgaaatgttg ctcatctttt tcctttctca aaagaaatat
     2221 cttttctcaa tattctatca caaataaggg cgaattacca actaaacaag gcgaagtttg
     2281 actttttcta gtttattggg gtacaataga gaaaagatag aaatgaagtg aaaaatatgc
     2341 tacctgctta tatgaaaatc catgatcaga taaaaaagga tattgacgag caccgttggg
     2401 ctattggtga gaggcttccc agtgaaagag atttagctga gcagtttgcg gtcagtcgca
     2461 tgaccctccg ccaagccgta tctctattag tcgaagaagg cgtcttagag cgccatgtag
     2521 gaagcggcac ctttgtttcc agtactcgag tacaagaaaa gatgcgaggg acaaccagtt
     2581 ttactgaaat tgtcaaatcc caaggtaaag ttccctctag ccagctcatt tcctacaaaa
     2641 aaaccattcc caatgagcaa gaagttgcca agctaggaat ttttccaacg gacaatatta
     2701 tccgaatgga gcgggtccgc tatgccgacc aagttcccct agtttatgaa gttgcttcta
     2761 ttcctgaaaa attcattaag gactttaaaa aagaagaaat caccagtcat ttcttccaaa
     2821 ccttgcaaaa acatggctat cgtatcggca aatctcaaca gaccatctat gctcgccttg
     2881 ctaaagaaaa gattgcccac tatttggaag ttgaaaaagg acatgctatt cttggattga
     2941 cccaggtttc ctacctagaa gatggtactg cttttgaata cgtaaaaagt caatatgtag
     3001 gcgaacgctt tgaattttat cttgaaaata attagattac cacgcaaaaa ctctctgtca
     3061 cggacaaaga gtctttttta tttttctaag aataaatctt tcaaagaaat caaagttaca
     3121 gcaaacaata tcattgccat accaagaaaa tcaatgggat aaaattgttc attcattatt
     3181 aagaaggcaa agaaaatcgc cgatattggc tcaattgaag ccaacaagct tgacttgacc
     3241 ggtcctatca gactggctcc tttaaggaaa gctgtatagg caaagacagt cccgataagg
     3301 ataatgcctg caaacgcaag gagaaaatca agactagtcg ggatatcggc ctgtagaacc
     3361 cctgtaaaag gaagagcgac caaacctgct atgaccattc ccacaccaat gaccaagctg
     3421 ctcccccact ttttaatcaa ggctatgggt aaaatgatat acagagcata agtaaaggca
     3481 gaaaagagac cccagaacag accagcaggt gtcatggata actggtccaa ctgcccatgt
     3541 gttgcgatca ggaaggttcc tccgatggcg aatatgatgg aaactatctc tcccagtgtc
     3601 ggtgccaccc tatccttgat acagctataa attaaaattc cgacaggaca aacatactga
     3661 agcaccgtcg ctgttcccgc attggtctcc tgaatagcag acagataggc gaattggttg
     3721 agaaaaagac caatcagagc aaaaataaga agagacagca aactctttct atcctttaaa
     3781 aagaccagta ttttatcctt tgcagtagca taagccaaga gcatgagaat tccaccagcg
     3841 attaaaagac gcaagttggt caagaccaga gccgaaattc cgtgtgccat taggtattgg
     3901 ccactcgttc ctgacaaccc ccaagcaata ccagccacaa ctgttagtaa agtccctttt
     3961 aaactatttg acatgtctct ccttactctt ctttgcgaat caagttcatc acttgattgc
     4021 ggtctaatat ccattgagct ctctcgtcct tttcataggt acgattcgat aggaaaatag
     4081 tggcttcttg cttctgacga ttccacatga taaaggtacc tgtatagccc gtatggtcta
     4141 gccaatctcc ttccaaattc catgctaaag aacgttcctt gtcatccaaa ggagaaaaat
     4201 tttgacttaa gtctcttgca aaatcatctg ctaaatagtg ttctaaaaag atttgtaaat
     4261 cctttatagt cgaaaataaa ccagcactcc cagcatgtct acccaggaga cgagccttgg
     4321 gatcatgcac tatgcctgcc tctacacctc taactgttgg aacagcaagc tcaactgacc
     4381 caaacttggt ttccgtcatt ccccaaggtt tccagacttg atcctttaaa atcacatcca
     4441 aatcttgatt aaaaattctt tccaaaataa agcccaacag caaaaaatgg acatccgaat
     4501 aaagaaaggc tggctgactt cgtctgttga gatgaaacat cgcttccttt aattcagggg
     4561 ctgttaaaag atcacgatta ggaataaaag gatcaaggtc tgttgcatga gtcaagagct
     4621 ggcgaatagt gatgtctgga taatcactct caggtaaaaa atctattacc agtctatcaa
     4681 tatctaattg acctatttcc cacaagaagg tacaaactgt gccaacccca acaaccttgc
     4741 tgacactagc taggtcataa actagtcctg cctcagtctg caagccatgc tctgggtcac
     4801 tctggcctaa atagaactct gtccattgat tgtccttaaa atacgcaaaa gaggctccgg
     4861 gataaattcc tgcctcgatt tgttcttcta tttttttaat aatcttggtc cacttcatac
     4921 ttcttcaaac cacaattcaa cattatttct atctttacaa aggaagaatt tttcagactt
     4981 aggaataaaa tattcagtag actcaaactt ctggcgaaga cttgctatgt ctaattcatt
     5041 gaccaagaac ttgagcatag ataagtccca ggtaaccgta ttgtccacag tcaaatcctg
     5101 cccctgagct ggaataaaat caagggatgc cccaatttca gatgattcca agaaactttc
     5161 gatatcagtt gggagatgta attccataga aatctcaaat ttacttaaag aaattgatac
     5221 caaatctgtt tgaaattcag gcttttctcc tacttctact agacttgctc tgtcatcttc
     5281 cgcatgaatc aaaatcaaat catcttctgg tgagaaaatt tcaaaagcgt agccattttg
     5341 acctttatat aatcgatgaa tcgaatctgt tttagataag attccttcaa tttctaaggg
     5401 attttccacc ttgacaatca atctagctag tttttttctt ccctctacct tacgagtacg
     5461 catactggga gcttcttcta aaaccagctt ttcaagaccc gtttggtcac ctagtgacag
     5521 aaaggccgat tcttctaaca aggccttcat tccaagggtt tcaatataaa atgtttcatt
     5581 taattttcta ttattagctt ttaaagtagg aataatccgt acaatctgat ttacattcat
     5641 aaattcctcc gtcacttttt attttaaagg attttagaat tttttacaag atattatgct
     5701 caaatttaac attatttagc tatttagtaa agatagtctt tcaaggcttt tgacaaagcc
     5761 tgataaccag caatactgag gtgcagtcca tcagttgtat attctttttt gagttggcct
     5821 gcttggtctg tcaaacaatc aaatactggc acaaattcca cctgcatata ggcagatgca
     5881 agctcttgat aggcttgatt ccagttctga attttttcat tcgagcggat atagactgcc
     5941 tgctggtact cctctccctc attgacaggc aaaatggaaa gcaatttaat ctctgtcaat
     6001 ggataatcgc gagcaacgga ttgaatgata gcttcgagat tattgagagc ctcattcaca
     6061 ggaacatcct ttccgatatc atttgtccca atcagaagaa aaattttatc tactgctcca
     6121 ccatatagat gagcatcaag gttctctagt aacagtcctg tctgatagcc acgaattcct
     6181 cgattgacaa tcgtctttga agtcccaaat agctcctgta gaggataata ctcgacaatg
     6241 gaatccccaa taaaaagaat gtttggttct acaacagaaa tgtgatttag gtgacgatac
     6301 ttagtttgaa ttttttcttg ttcctttagg agccaatttt ctaataactg tactgccact
     6361 tcattctcct ttttctaacc agttttccaa gacttgataa actcctcctt ggctgttggc
     6421 tggtgctaga gcagtcgcca cagctttggc tttctcatca gcattttcca tcgcataggc
     6481 aattccagcc atttcaagca tttcaacatc attttcacta tcaccaaaag ccatgatttc
     6541 ttgggatttc aagtcccagc gcttgagtaa ttcctccaag ccccatgctt tatgaatccc
     6601 agcttggagg atatcaatgc aaccatagcc actggataca gctcggacac ggccatcaaa
     6661 gagagcattg atttcttcca aaaccgaact caaacgttcc tcaccaacaa ccatgctcat
     6721 cttgagcaca ccaccaaaga ggtcagatgt taattcatcc acaaattgca tccgttggta
     6781 gaatttttca atcatttctg gagtcataaa actttcaaga tctgtaaaaa tcgtaccttc
     6841 cttgacaaaa tcacccttca tccccgttac aacaaactgg tcctgacacg ctcgaccctt
     6901 gaaatgagtc aaagccttgt tgacaatggc gtcatcccat gtctgagcct gaatcaattc
     6961 attgttttca aaaatacgag cgccattagc aacaaccaga accactcgat ccaccaaggg
     7021 actcagtagt tgtctcatgc ggtgaatttc attgcccgtc gcaatgacaa aacgaatgcc
     7081 cctttgatcc aactgatcta aaatcttttc caatcgtggg agatcaagct gacctctagc
     7141 atccagcaag gtcccatcca tatctgtcgc aattacctta atcatcattt actttcctct
     7201 ggattcaagc taataccact tcaatcccac atgttcattc atttctttat aggctgtatc
     7261 aattcgttcc ttagtcgctt catctaactg gtcacgatga ctgccatcct ctataaaatc
     7321 ttccaaaata taagtttggt aatgatacaa gggatatcct tctggtgaaa aggttccctt
     7381 tggtgttcga ttgacccaag taggatgagc tttagctgtt ccgatagttg tttttccatc
     7441 cttcttcttg atggtgacat ccatgagaac accacgttca gtccacttag cattctcttc
     7501 atctcccata gattcaatcc gttgattgga aatgaagttc cccatttaat agacaatgag
     7561 cttcttatct ccatcttttt ccaccgtttc agatggttca acaacgtgag gatgccctcc
     7621 aaagataata tccgctcccc aatcgatcat cttgtgataa agagcttttt gttcttcagt
     7681 tggttccaat cgatactcaa cacccatctg aagcatgata atggtgatat ctgcttcctt
     7741 ctctgcccgt tcaatttcaa ccttcatctt atcttcgttt aaatctgaaa gataacgatt
     7801 atagtcttcc tgagaaatat actgctcaat tccattgaaa ccataggaat aggctaacaa
     7861 tgcaaccttg ataccattca cttccttaat gaccagcgga gcctgaacac gtggttcgtg
     7921 cgtataaact ccgattggag tgattccagc tttctcaata atatcggccg ttgaaataac
     7981 tccctcaagt tgaaataact ccctcaagtt gcgaatccaa aatatgatta tgagctaaat
     8041 ccagcacatg ataacctgcc tccttaatag catccataac ttcagcagga gcattaaaga
     8101 gaagataacc cgctaaataa tgatccttat taatggttcc ttcaaaatca ccaatagcta
     8161 aatctgcttg cttgagccaa ggagtcacat actcaaaatt ttcatgaaag tcataggtac
     8221 cgtcttcttt tttagctgaa aagaaaagtc catcgtggta gagcaaatcc ccgtgggcca
     8281 taattctggc agttttttcc tcttcctact cctgagactt ttgcttagtc ccctcttgag
     8341 aaatagtatc tcgtttttga ctagtcaagg gattccttgg aagctttcaa acaacaagac
     8401 caagcccttc ataaaacgaa aagctaaacc accctgattt cgattttatc ttctttgtat
     8461 cttcattctc cctactttct tatgcaagcc ttttcttttt attatatcac agataagtat
     8521 ttctttcaca attgaattga acttcccatc tattttctat aaatcctaaa tgccataatg
     8581 ctttcaattc ttgtcatttt gtgatatcat gtagaggaaa tgaactaatc cacagtggct
     8641 tatttcaagt ataccacttg ggctttggca gtagctaact gcactaaata taatataagg
     8701 agagaaaatg tctgcaatag aacgtattac aaaagctgct cacttaattg atatgaacga
     8761 tattatccgt gaagggaatc ctactctacg cgcgattgct gaggaagtca ctttccccct
     8821 atctgaccag gaaatcatcc taggcgaaaa gatgatgcaa ttccttaaac attcccaaga
     8881 ccctgtcatg gctgaaaaaa tgggactccg cggtggtgtt ggactggctg ctccccagtt
     8941 agatatctca aaacgcatta tcgctgtttt ggtacctaat attgttgaag aaggcgaaac
     9001 tccacaggaa gcctacgatt tggaagccat tatgtacaat ccaaaaatcg tctctcactc
     9061 tgttcaagat gctgctcttg gcgaaggaga aggttgcctg tctgttgacc gtaacgtgcc
     9121 tggctatgtt gttcgccatg cccgcgttac tgttgactac tttgacaaag atggagaaaa
     9181 acaccgtatc aaactcaaag gctacaactc cattgttgtt cagcatgaaa ttgaccacat
     9241 taacggtatc atgttttacg atcgcatcaa tgaaaaagac ccatttgcag ttaaagatgg
     9301 tttactgatt cttgaataaa gaaaatcccg ttgcaagacg gggttttgtg ttataataga
     9361 ggcatgaaaa caaatgatat tgtctatggc gtccacgccg ttaccgaagc cctccttgca
     9421 aatacaggaa acaaactcta cctccaagaa gatctccgag gtaagaatgt tgagaaagtc
     9481 aaggaactag ctacagaaaa gaaggtgtcc atttcttgga catcaaaaaa atctctctct
     9541 gagattactg aaggtgctgt tcatcaaggt tttgttctac gagtgtctga atttgcctat
     9601 agcgagctag attacatcct tgcaaaaaca cgccaagaag aaaatccact tctattgatt
     9661 ctagatggtc taaccgatcc ccataatctg ggttctatct tgcgaacagc cgatgcgacc
     9721 aatgtttcag gtgtcatcat tcccaagcac cgtgctgtcg gagtaactcc tgtcgttgcc
     9781 aaaacagcca caggtgctat tgaacacgtt ccaattgccc gagtgacaaa cctcagtcaa
     9841 accttagata aactcaagga tgaaggcttc tggacctttg gaacggatat gaacggtact
     9901 ccttgccaca agtggaatac aaaagggaaa atcgccctca tcatcggaaa tgaaggaaaa
     9961 ggcatctcta gcaacatcaa aaaacaggtc gatgaaatga ttaccattcc gatgaatgga
    10021 catgttcaaa gcctcaatgc cagtgttgct gcggccattc tcatgtacga agtttttcta
    10081 aatagactat aaaaaagttt ccagtcatct gattggaaac ttttttataa ttaactatgt
    10141 tctgtgataa acttgtaggc ttcttgacca gcgatagctc catctccaac tgctgttgtt
    10201 acttggcgaa ggtctttcaa gcgaacatct ccaactgcaa agataccgtc gactgcagtc
    10261 ttcatgtggc tatctgtcac aatccagcct gcctgatctt ggatattcaa ttctttaaca
    10321 aaatcgctaa gagggtccaa accaacatag ataaagacac caccgaaggc ttgctctgtc
    10381 acttgacctg ttttcacatt ttcaaaaacg acagattcta ctctgttttc acccttgatt
    10441 tccttcacta cagaatccca gataaagctg attttttcat tcgcaaaggc gcgatcttgt
    10501 aaaacctttt gggcacgaag ttggtcacga cggtgaacaa tggtaacagt cttagcaaaa
    10561 cgagtcaaga agagggcttc ttcaacagct gaatctccac caccaactac caataaatct
    10621 tggtcacgga agaaagcacc atcacacaca gcacagtaag aaacaccacg actgttcagt
    10681 tcttcttctc caggcactcc caaaggacgg tgtttagaac cagttgctac gataactgta
    10741 cgtgtttcat atgtttggtc atcagtcatc actttcttaa aatcaccatg gtcttcgaca
    10801 ttttcaacat aaccataaat gtgctcaaca ccaagatttt caagtggttc aaacatcttt
    10861 tcagccaatt caggtccact aatattagcg tatcctgggt aattttcgat atcagatgta
    10921 ttattcatct gaccacctgg cagaccacct tcaatcaaag ctacttttag attgcttcga
    10981 gcagcataca aggccgcagt catccctgca ggtccagcac cgataataat agtatcgtac
    11041 atatagattc cttctttctt gttgtaacta tctttattct aactctttct tgtcaatcac
    11101 gcaaggatta tgccttgaaa acaagaatta aactcataac cgcaaaggat aatactggga
    11161 caaccaagac tccaatcata atcatatcat agagatgggc ttggcgagcc ctggctgtct
    11221 tatcaactcc cgacatggct ctcagaccaa tccaaatccc taaaaaaatc agaacaagga
    11281 tggtggtcaa gatcaaactc tcgaaatata aagaaaatag ttgcagtagc atgatttctc
    11341 tcatttctat cttttttaaa gagtaaactc agctagtcca actaactgag ttttccttta
    11401 tctattatat caaatataag tccgtttgta actagcgaag aattcttttg tccgctcttc
    11461 tttaggggtg tggataatct catccggagt tccagactcg atgattttcc ccttatctaa
    11521 gaagagaatt ttatccgcaa cttgggctac aaaggacatg tcatgactga ccaaaatcat
    11581 ggtctgacct gacttagcag catctgcaat agacttttct acttcaccga ccaattctgg
    11641 gtcaagggct gaagttggtt cgtctaagag caaaacatct ggtttcatag caagcgcacg
    11701 cgctagggca acccgttgct tctgtccacc tgataaatgg cgaggataat ggttttcacg
    11761 gtccgaaagc ccaaccttag ccaactcttc cttggcaatc ttagtcgctt cttggtcaga
    11821 taatttcttg acaacaacca agccttcttt cacattatca agtgctgttc gacgttcaaa
    11881 taaattaaac tgttggaaaa ccatagacaa cttacggcgt agggcaagga tttcttcttg
    11941 agtgatttta gaaaaatcaa ctgaaaaacc atcaatctga atagagccac tgtcaggtgt
    12001 ttcaagataa ttgagactgc gaagaaaggt tgattttcca gctcctgaag aaccaatcaa
    12061 ggctacaact tccccttttt gaatatccaa gttcagatga tccaagacag tctgtcctga
    12121 aaaggatttg cttaaattcg aaatcttaat cattaacgaa ggtctccttt cacatctgtt
    12181 tgcactgtat caggtgcaga aatagccatt tttctctcga tgaaacgacc gaggctttca
    12241 attccgatat tgactaccca ataaacaagg gcaacagaga tgaagcgttc aaaatagcga
    12301 taatcagctc cacctagaat ctgagcttgg gcaaagactt ccacaacacc cgcactaaaa
    12361 gctagagatg ttcccttggt caaaccgatg agggaattaa tcaaggttgg agtagctacc
    12421 accgctgcat taggaataat cactcgtcga taaacttgcg ctcgggtcat acccagactg
    12481 cgcgccgcct caatctcacc aggattaact gagagaatgg ctgcacgaat ggtttcacta
    12541 gcataagctg cctcattaaa ggcaaaagcg acaatcgcaa aagctgcagc tggaatcgca
    12601 ttgatattga gaccagttcc ccattgctga ttgagggctt tcaaagccaa aggaattccg
    12661 tagtaggtca acatgagttg caccaaaatc ggtgtccctt ttaagaaact aacaaagaag
    12721 gcctgcaagg gatataaaat cttgacacga ttgatcttca caatggcaaa aagaagcgcc
    12781 aaaaccaagc caaaaagggc accaccaatt gtcaacataa ttgttgttgg aagttgttgg
    12841 acaattctag ggattccatc aaagaccgaa cgtaggctaa acagcttgcc atccggaatc
    12901 aattgcatca agttttggta ccaatctgat gctaaaatcg ttgtaacatt cataaaaaca
    12961 tcctcttctg ataatgattc attctaccat gcttctgccg tcaatgaaat tatttgctac
    13021 ggtcagatac agactttgtc tacctactag tttatcatac tttgaaacag ggaagttata
    13081 tattttatct atcaaagaga tagataaaaa ctatttcagt cccagttctt cataagattt
    13141 tcgataaccg atttgcttaa cagttccatt ttctactaaa atgggccgtt ttaacaacat
    13201 accgtcactt gctagcaact cagccgcttc ttggtttgac aaacttccta ccttatcttt
    13261 tagccctaat tcacggtatt tgataccact ggtgttgaaa aattgcttca attcaaatcc
    13321 tgaggtttct agccaattca aaatgacttc ttggctaggt gtttcttcca cgatatggac
    13381 ggctttatag tccacaccta attgatttaa ttcttgtttt gcttttttac aagttgaaca
    13441 tttggggtat tcgataaatt ctaacatgtg cttctccttc tatttgttta tatctttaaa
    13501 atctacgcct tcatgctcca agagccaagc tttcttttcc actcctgcag catagcctgt
    13561 cagacgcttg cctgctccca acacacgatg acaaggtact aggatagacc aaggattgcg
    13621 tcccactgct ccaccaattg cttgagcaga agccacttgc aggtcttgag caatttgtcc
    13681 ataggtcact gtctgaccat aaggaatgcc ctgtaaatag tcccaaactc tcttttcaaa
    13741 attcgttccg attggcgcca agagcaagtt ggataaatcc tgaggcttgc ctttaaagta
    13801 atcatctaag caagcaataa ctgggtctaa aataggatga ctaacaactt cttctatcgt
    13861 ttcatctcct agtcccctct caaaatgctt ctgctcctga acccaaattc catacaaata
    13921 atggtcatca gctacaagtg atagaatacc aattggtgag gagtagagga tttttacata
    13981 cttcttttgc attatttctt taatttttga taggccaagc gttcgccatc tactggcacc
    14041 ttaccaactt gtttaaaacc aagtttttca aaaatatgtt gcataacctt gttttcagca
    14101 tgcgtatctg agcgaaaatc aagataatca aaaccttcaa tcaagccctc taagaaggtt
    14161 tgagcaactc cttttccctg cacatctgct gccacagcaa tacggtgaaa gactagatac
    14221 tctgactctc cagcttgcca gtttccctca taaatagctt cataggcctc ctctggactc
    14281 ttggtcacag cagcataggc tagcagttct ccctcttcca aggctacgta ggcttgccct
    14341 gagatgatat catcgataat aacatctgca tttggatagc cattttgcca ctggttacta
    14401 ccagcatctg ctaaacattt tttggcatcc tctatcacct gcatgatggc atctacttca
    14461 tttggaaaag ctaaacgaat ttccatcttt tttcctcatt tctgactagt ttctcccatc
    14521 atagcataat ttaagtcttt ctacaagcag ttaaaacttg actttgtatt tttgttattt
    14581 tataatctag ttatcaaaac tatataaaaa ggagttgaaa atgaaaacta ccttttccta
    14641 cccaaaatgg gcagaaattc caaacattaa cctctatctg gaccaggttt tgctctatgt
    14701 caatcaggtc tgcgccccta tctctcctaa taaagacaaa ggcctaacag catctatggt
    14761 caacaattat gtgaaaaatg gttacctgac aaagcctgac aaaaaaaaat accaacgcca
    14821 acagattgcc cgtttgattg ctatcacaac cctcaagtct gtattttcta ttcaagaaat
    14881 agcccagaca cttaatactc tacaaactca agcaagttca gaccaactct acgatgcttt
    14941 tgtggactac atgaaccaag gaattgaccc agctaaccct attatccaaa ccagctgcca
    15001 aaccgttaaa ctctatcatc aaactctaga cttaatcgat catactcaag aggaggtaat
    15061 ccaatgaaca ctagtcttaa actcagcaaa caactcagtt ttggagagga gattgctaat
    15121 agcgtgaccc atgctgtggg tgcagtcatc atgcttatct tgctgcctat ttcatccatc
    15181 tatagttatg aagcacacgg atttttatcc tctatcggcg tttccatttt cgtcatcagt
    15241 ctctttctca tgttcctatc atccaccatt tatcactcta tggcctatgg ttcgacccac
    15301 aaatatgttt tgcgaatcat tgaccattct atgatttacg ttgccattgc cggctcatac
    15361 acgcccgttg tcttgacctt gatgaataac tggtttggct atctgattat tgtcatccaa
    15421 tggggaacga ccatctttgg tattctctat aaaatctttg ctaaaaaggt caatgagaaa
    15481 tttagccttg ctctttacct gattatgggc tggttggttc tggctatcat tcctgccatt
    15541 atcagtcaaa cgacacccgt tttctggagt ctcatggtaa ctggcgggct ctgttataca
    15601 gttggagctg gattttatgc caagaaaaaa ccttatttcc acatgatttg gcatctcttt
    15661 atcctagctg cgtccgcact tcaatacatc gctattgttt attacatgta aaaaagttga
    15721 gaaattcaat ctcaactttt ttctttacac atattgataa agtactggtg caagcgcaca
    15781 tcatcagtca attctggatg aaaagaactt accaacatat ttttttcttg ggctgcaaca
    15841 atttgattgt tcactgttgc taaaatttct acaccctcac caacactact gataatcgga
    15901 ccacggataa aggtcattgg aatcttgcca actcccttac attctgcttc cgtgtagaaa
    15961 cttcctaatt ggcgcccata agcattacgc tcgaccacca tatccatagt tcctagatga
    16021 ctctctttct gagaagtgat ttccttagcc agcaaaatta agcccgcaca ggtcccaaac
    16081 actggtaagc cagatagaat ggcttctcgg atgggaagta gcatgttctg gtcacgtaag
    16141 agcttgccca tggttgtaga ctcaccacca ggcaaaatca aacccgacaa gtcactctga
    16201 tcttgctgaa aatcatctag atttctgagt tctacactct cgacacctaa ttgatctagc
    16261 acttttgcat gttctgcaaa ggccccttgc aaggccaata ttccgatttt catctatttt
    16321 cctcgttcag ccatgagaat ttggatttca ttttcattaa taccaaccat ggcttctcct
    16381 aaatcttcag agatttgagc taggatttga ggattacgga agttagtcac agccttaaca
    16441 atggcactcg ctcgtttaac aggatctcct gacttgaaaa tacctgaacc gacaaagacc
    16501 ccctctgccc ctaattgcat cattaacgca gcatctgctg gcgttgcaac acctccagca
    16561 gcgaaattta caactggcaa ttttccatgt tcatgaacat attggaccaa ttctacaggg
    16621 acttgcaaat ccttggcagc aacataaagc tcgtcctcac gtaagttttg aatgcggcga
    16681 atttcctgat tcatcatacg catatgacga acagcttgga ctatatcccc tgtccctggt
    16741 tctcctttgg tacgaatcat ggaagcacct tcagcgatac gacgcaaggc ttcacccaaa
    16801 tccttagcac cacagacaaa aggaacttgg aattctttct tgtccacatg gaaacggtca
    16861 tcagctggag atagaacttc actctcgtcg atataatcaa tttcaatagc ctctaaaatc
    16921 tgagcttcaa caaaatgccc gattctgacc ttagccatta ctggaatact aaccgcttct
    16981 tggatttcct taatcatctt tgggtcgctc atgcgggaaa ctcctccagc tgcacgaata
    17041 tcagccggaa ttcgttccaa ggccatcaca gctgccgcac cagcagcttc tgcgatacga
    17101 gcctgttcag gattctgcac atccataata acaccaccct tgagcatctg tgccaagttt
    17161 ttatttagtt cataacgatt ttcagtcatt tgttttatcc tcatcatttg tattggtagc
    17221 taccttttca ttttaagtca gaacagaatg aagcacaaga taaaaaaact ataattgtat
    17281 ggggacagat tagctaaaaa ctatctgacc ttaacttaag gccagatagc tcattcattt
    17341 ttatttttca gccgtaaggg cagccattgt gatgtagttg tatggtttgt tgaagtgtgg
    17401 caagaagaag aggtctgtca atgccaattt atcaattgtc acatgctctt ggatagcaag
    17461 tgagaacatg tggattccca tgctaattgc aatatcatgt gaaaccattt gggcaccaag
    17521 aatttcacgg ctatctttgt caaagacaat cttaattgct acttcatggt tgtcatgttt
    17581 catgaattct ggtttttgaa gatcgttaaa gcctgtttca gttgcgttgt aaccagcagc
    17641 tttcgctttt tcaagagtca aaccagttga aaccatgtga agaccgtaga ttgagatacc
    17701 atttgaacct tgaacaccga ttccttccaa ttcatgtcca caagcattgt aggcaccaac
    17761 gataccagtg cgaacagcat ttgaagcaag agcgatatag cttgtatctt tacgagcatt
    17821 gtcataaaca gtcgcacagt caccaacagc gtaaacgcct gggatagatg tttcttgttt
    17881 cttgtctaca aggaaggcac cgttgcggaa gagttcgatc ttaccatctg caagggctgt
    17941 gtttggacgg aaaccaactg caaggataac catatccacg tcaaagcttt ctttgtcagt
    18001 aatcaagcgt tcaactttac cgtcaccttc gattgcttta acagtttgac ctagagccaa
    18061 gcggatgttg tgatcttcca agttcttcgc catcatttgt gtgaagtctt tgtcatagta
    18121 accgttcaag acagtatcaa cgatatcaac aaggacaact tcttttccaa gacgttcaaa
    18181 ggcttcagca agttcaacac cgatgtaacc accaccaaca acggcgatac ggtcgaggtg
    18241 ttggctcttg tcagaaagtt tattgataac ttcttcagca ttttggtaca atttcacgaa
    18301 ttgtacgttt tcaagagttg ctttaaattc gcggtttcct ttaacaattt caacaccttc
    18361 gattggtggc aagattggtg tagaacctgt agcgaaaatc aatttttcgt atgattcttt
    18421 gtgctctttt ccttcaactt ccgctgtaac tactttgtta tcatagtcga ttgaaagaac
    18481 aggtgagttc atgtaaactt tagcaccttt agcttccaat ttttctttat cagaatagaa
    18541 caagccttca gcaccgtcaa tttgttcacc aatccaaaga gccattccac atcctaggaa
    18601 agagatgtta gagttttggt caaatacaac aatttcgttc tcatttccaa aattatccaa
    18661 catggtattg atacatgctg taccagcgtg gttagcaccg actacaacga ttttactcat
    18721 aaaaatttcc tgccttcatt ctaaatttac cttactagta taccatttac cgttagcgtt
    18781 tacaaggggg gtactattat ttcagcattt tttatcaaaa ataattcccc atttatcctg
    18841 ttttcaagcc tcatgaattt tatgagcata tttcttgact ttttccaaat tttgtttgtg
    18901 aaaattctaa ctttatggta ttataataac atgaaaatga aatgtaaggg cttcaattta
    18961 gatgattatt tgatattaca acttattttc tataagagaa aggagttggt agcttgactc
    19021 ttcgttcaca ttctgaacgg ctaatgggga ctactatcac tatttcatta gtggatgagc
    19081 aagccgatat ctttctccaa aaatcctttg acttgctcaa agaacttgaa taccgcttca
    19141 acgccaatag tcaagaatct gagttgatgg aaatcaatta tcaagcagga atagcccccg
    19201 tcacggttca tccagacctg tttgagctga tttcacttgg gttagagcat agcctagcgc
    19261 tctctagcca cctcaatatc agcattggtc ccttaattca aacctggcgt atcggttttt
    19321 cagatgccaa ggtcgcccag cctcaagaaa ttgaatcggt gctgcctcta atcaatcctc
    19381 atggtatcga gttagattct tctacttcta ctgtgttttt aaaacagaaa ggaatgaaga
    19441 tcgatctagg ttgtttagcc aaaggataca gtgcggataa ggttgcccaa tttcttagga
    19501 aagagggggt gacttctgcc ttgatcaatc tgggagggaa tatcctgacc attggaaaaa
    19561 atcaggcaag aggggataac ccatggcaaa tcgggattca agacccagcc aatcctaggg
    19621 gaaatcattt aatgaccatc cctgttgtca ataaatctgt cgtgacttca ggcatttatg
    19681 aacgtcacct gaccgtcgat ggacaagatt accatcacat ttttgacagt caaacaggat
    19741 atcctgttga aacggaacta gcgagtctaa caatcatctc tgataaatca gtcgatggcg
    19801 aaatctggac gactcgactc tttggagaaa gacctgcttc tatcctctgg caagtcgaaa
    19861 gtttggaggg catcgaagtc atcctcatcg ataaagaagg ccacctaagc tgttcttcag
    19921 gaattcctac tctatagaga caactgtttc aatggaattt taaaattgta ttatgtaaaa
    19981 agagaaagga aatctcatgt taaaacttat tgctattgtt ggaacaaatt caaaacgttc
    20041 tacaaaccgt caattgcttc aatacatgca aaaacacttt tctgacaaag ctgaaattga
    20101 gcttgttgaa atcaaggcca ttcctgtctt caacaaacca gctgacaagc aagtacctgc
    20161 tgaaatattg gaaattgctg ctaaaatcga agaggcagat ggcgttatta tcggtactcc
    20221 tgagtatgat cactctattc cagctgtttt gatgagcgct cttgcttggt tgtcttatgg
    20281 tatttaccca cttttgaaca aaccaatcat gattacaggt gcttcttacg gtacgcttgg
    20341 ttcatctcgt gcccaattgc aacttcgtca aatcttgaat gctcctgaaa tcaaggcaaa
    20401 tgttcttcca gatgaattct tgctctcaca ctctcttcaa gcatttaacc caagtggcga
    20461 cttggttgac cttgatgtta tcaagaaatt ggatgccatc tttgatgact tccgtatctt
    20521 tgtaaaaatc acagaaaaat tacgtaatgc acaagaatta cttcgcaaag atgctgaaga
    20581 ctttgactgg gaaaatttgt aagataggag accaaaaaga atgaaatttg ttggacttgt
    20641 tggatcaaac tacgatcaat catataaccg taagctcttg gaatttatcc gtcgctactt
    20701 caaactcaaa tttgaattag aagttcttga aattgacgaa gttccaatgt ttaaccaaga
    20761 tgaaaaatgg gatgaaagtt tccaattacg ttatttatat aacaaaatta ctcgtgcaga
    20821 tggtgttatc attgctactc ctgagcataa ccacactatc tcagcttcac tcaaatctgt
    20881 acttgaatgg ctttcatacg aagttcatcc atttgaaaac aagcctgtta tgattgtggg
    20941 tgcatcatac tatgaccaag gaacatcacg tgctcaagtt caccttcgta aaatccttga
    21001 tgctccaggt gttaatgcct acacgcttcc aggtaacgaa ttccttcttg gtaaagctaa
    21061 ggaagctttt gataacaacg gaaatatcac caacgaaggc actgttaaat tccttgaaac
    21121 ttgcttagat aactttgtta aatacgtagg agtcgtttcg aaattgaaaa aaccaaaacc
    21181 aatcgaatca gaagacttgg attgtggaaa accaatcgct acaaccatca cagaagttga
    21241 ccctgacgat ccagaatggg tagaaaaagt tgcagcaatc actggtgctg tttctggtga
    21301 tacctatgtc aaattggacc acggtatcct aacagttaac caaattgata tgttcttgaa
    21361 agctatgcca tttgaattga catacgctga cgacaacaac caattcctct actacaacaa
    21421 cgctcaccaa gatccagaca ctatgttcgc taaacgtgta ccacctcaat caggtagccg
    21481 tatgtcgact gttcatggtt ctcttccacc agcacgtatg aagaacgtag agtgggttat
    21541 cggaacactt cgcaacggaa accaagaata cgtccgtacg atcgttccag gttctcctgc
    21601 aggtgttatc aacactcaca actaccaagc aatgtactat cctgatggat catacgctgg
    21661 tatcaatgaa atcgtcttta acttccaacc atggcttgac tggtacctaa aagagactgg
    21721 tcaacgtttg gtgggtggta gcggaccatt tgctcctgct gccggaggtc atggagacgc
    21781 cgatgctact tctggcgctt ctgattcagg ggatgctgga ggccacggtg gtgacgcaga
    21841 cgctacagcc ggtgcaagtt actaatgata gtttttagga accattatgg ttcctttttt
    21901 agcgaaaaaa gactagcaaa cacaaactgc tagtctcttt gttatcgttt catctatctt
    21961 tgttaaaaga aagagtactt atactcaatg aaaatcaaag agcaaactag gaagctagcc
    22021 gcaggctgta cttaagtacg gcaaggtgaa gctgacgtgg tttgaatttg attttcgaag
    22081 agtattatta tgaatttggg tcatcaagac tacggccatg taatcctttt tcacgttgta
    22141 cttggcgtag tttttctggt gtaacatcgt ttccttcttc gtccacaatt ttgattcctt
    22201 caatgtggtg acgaacagcg cggcgataac cttcgatgta ctcctcacgt agtttggctt
    22261 gttccacttt ttcttctgat gttaagcctt ctgttttttt ctttttagca agctcattga
    22321 tacgagcaat ttttttcgga tccatttctt ctcctttgta ataagataaa gtccgtttat
    22381 caaattttat ttagtgttaa tttggttaaa acaagcaaac ttagctgctt tcttggttag
    22441 ttgtgacaag attgccaaac gattttgacg gacagcctga tcttcagcca ttaccatagt
    22501 attttcaaag aaagcatcaa tgactgggct aagcgcaaag agttgtttca attgctgact
    22561 tgcaggtcct gataaaacga gtgtttctac tgcttctgcc aaagcttttt cttggtcatt
    22621 ctcaaatagt gctgaatcaa ctgtagcaac cccttctgcc ttctcagcca ggttaaaggc
    22681 acgagaaagt gattcaacag atggtttaaa atattcttcc ttgcttactt ctacgagagc
    22741 acttgctgct tccaacatat ctgccacaac aaagtttgaa cctgcaagaa ctgcttcctt
    22801 gatatctttt ggagtagagc ccatcatctt atcaacacga gccttgataa agtccataac
    22861 ctctgcttta ttttcataag tcaaactgtc aaatttcaat gcataaaggc tatcaatcag
    22921 ctcatccata gcaatgtgcc aaccaaaggc atccaagata cgaaccacac cttgagttgc
    22981 acgacgaagg gcataagggt cattagaacc tgatggaatc aatcctactg agaagaaact
    23041 caaaatcgta tccaatttgt ctgcaatggc tagaactgcg ccgaccttgc tctctggaag
    23101 ttctccttca gctgatgtag gcatgtagtg ttcacgaata gcagctgcca ccgctggagt
    23161 ttcaccagca agaagggtgt atttttcacc cataattcct tggagttcgt caaattcacc
    23221 aaccatacct gtcaataagt caaacttgta aatggctgct gcacgagcaa ggtcaactgt
    23281 ttcatccact gacaaaccag ctttttctgc caaaagtaca gtgatttgac ccgtacgaat
    23341 catgtgttca cgaagggaac caatcttctc atggaaggtg acattgttta atttttcaac
    23401 aagatctgaa atcaccaatt tttggtcttc acgccagaag aattctccgt cttccaagcg
    23461 ggctaccaag actttttcat ttcctttaat gacatttttc aaacgctctg cgtttccgtt
    23521 acgaacagaa atgaagtttg gcaagagttt tccatcttga tcacgaacaa caaagtaacg
    23581 ctggtgttcc ttcatagaag tcaccaagac ttcttctgga acttcaaggt atttagcatc
    23641 aaaacttccc atgaaggcag ttgggtattc aaccaaattc aagacttcat tcagcaaatc
    23701 cgcatcaatt tcgatacgta caccatgttt tgcctcaatt tccttgattt ggtcaacaat
    23761 catttgctca cgttcacatg gatctgcgat tacaaactgc ttacgaaggt cttcttcata
    23821 gctcaatgct gactgaattt tggtttcttt ccccaagaaa cgatggccac ggctcacacg
    23881 acttcccttg atatcaagga aatccaagtc aaactcttgc tcatccaaga gaacagttaa
    23941 agtgtggaca ggacgaatgt attcaaagct atttccagcc cagtgcatgc tgacagggaa
    24001 agtcaatgac ttcaagacat ctacaacacc aggaacaatg gcttcaactg cttgaccaac
    24061 ttcttcctta gtgacataga catattcttc acccttgatt tcacggaatt cgatatcttc
    24121 aacagtcaag ccttttccac ggacaaatcc ttgagctgct ttggtaaagt ttccatcact
    24181 atccaaggca attttctttg ctggtccctt gaaatcttct gtcaaatcag actgtttgtc
    24241 tgataaacca gtcacacgaa cagccaaacg acgtggtgtt gagaaggttt gaatggcttc
    24301 aaaagacagg cggttttcct tgaggaaggc tgccattttt tcgcctagtt gtttttcact
    24361 tggtgtgaca acataggctg gtaattcttc aagaccgagt tctactaata agttttttgt
    24421 catgtttttt cctttacatt ttcttcaatc ttttttgata tgcaccttag gtactgggga
    24481 cgtcgctaac taactctgtg agtctgtatg gaaatccaat gctaaattta tcaagatttc
    24541 caacaatctc atcaaagtgg atttagctga ctgatttttg aacctaaggt ttcaaaaatc
    24601 cccacataac agtacggcgg tgcatatccc tctagcaagt cttcgacttg cctctaacga
    24661 ttttagagta cagtattact cactattctg cgtcttctgc taaaagttta actcgtgttt
    24721 cttcatccaa aagtgggtaa cctaggcgtt tgcgttctgc aacaaaggtt ttggctacaa
    24781 cacgggccaa gttacggata cgagcgatat agcctgcacg ctctgttaca gatacggcac
    24841 cacgcgcgtc aagcagatta aaggtatgtg aacatttgag aacatagtca taggcagggt
    24901 gtaccaagcc ttcttctaat gcacgaccag cttctttttc aaacttatca aagttttcaa
    24961 gcaaaatttc ttggtccgaa atttcaaatg aatattttga gtgctcatac tcaggctgga
    25021 taaagatttc tccgtatttt acaccatcag cccactcgat atcatagaca gagtctactt
    25081 cttgaatgta agaagccaag cgctccaaac cataggtaac ttccgcagtc acagggccag
    25141 ttgccaatcc accgacttgt tggaaataag tgaactgagt gatttccatt ccgtcaagcc
    25201 aaacttccca accaagacca gctgaaccag ttgatgggtt ttcccagttg tcctcaacaa
    25261 aacgaatatc gtgctccaaa ggattgattc ccaatttttc caaagactca aggtaaagtt
    25321 cttggatatt tgatggagaa ggcttcatga ccacctggaa ttggtggtgt tggtagagac
    25381 ggttagggtt ttccccataa cgaccgtcag caggacgacg tgatggctct acataagctg
    25441 cattccatgg ctcaggtccg atagcacgaa ggaaagtgta aggactcatt gtccccgcac
    25501 ctttttcatt gtcataagcc tgcataagca tacaaccttg gtcattccaa aattgttgca
    25561 aagtcaaaat aatttcttga aatgttaatt tcttagacat tgtttactcc ttaataaaaa
    25621 atgatttctt gcgacacgag tct
//
LOCUS       DAVBOG010000031        24519 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.031, whole genome shotgun sequence.
ACCESSION   DAVBOG010000031 DAVBOG010000000
VERSION     DAVBOG010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 24519)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24519)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24519
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.031"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(98..2356)
                     /locus_tag="VQ865_001368"
     CDS             complement(98..2356)
                     /locus_tag="VQ865_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3135698.1"
                     /translation="MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSL
                     FKGMTDLNNRDFDPFGDFFNDLNNFRPSSNTPPIPPTQSGGGYGGNGGYGSQNRGSAQ
                     TPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
                     GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEI
                     RKREDIILFIDEIHEIVGAGSASDGNMDAGNILKPALARGELQLVGATTLNEYRIIEK
                     DAALERRMQPVKVDEPTVDETITILKGIQKKYEDYHHVQYTDAAIEAAATLSNRYIQD
                     RFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRD
                     QIAKYKEMQKKKITDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKS
                     HVIGQDDAVDKIAKAIRRNRVGLGTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSA
                     DSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTEKVRHNPYSLILLDEVEKAHP
                     DVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKTEASVGFGAAREGRTNSV
                     LGELGNFFSPEFMNRFDGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIRLDVTDKV
                     KEKLVDLGYDPKMGARPLRRTIQDYIEDTITDYYLENPSEKDLKAVMTSKGNIQIKSA
                     KKAEVKSSEKEK"
     gene            complement(2585..2815)
                     /locus_tag="VQ865_001369"
     CDS             complement(2585..2815)
                     /locus_tag="VQ865_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HET3135699.1"
                     /translation="MESHLVRIINRLEAMANDGGNLKRNFEREGVVVAEVAYSHDEEN
                     GPIFTLRDVEDRETYTFDSIDLIAMEIYELLY"
     gene            3005..3688
                     /locus_tag="VQ865_001370"
     CDS             3005..3688
                     /locus_tag="VQ865_001370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001011621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3135700.1"
                     /translation="MNFSFLPKYLPYFNYGAVVTILISICVIFLGTILGVVLAFGQRS
                     KFKPLVWLANLYVWIFRGTPMMVQIMIAFALMHINAPTIQIGILGVDFSRLIPGILII
                     SMNSGAYVSETVRAGINAVPKGQLEAAYSLGIRPKNAMRYVILPQAIKNILPALGNEF
                     ITIIKDSSLLSAIGVMELWNGATTVSTTTYLPLTPLLFAAFYYLIMTSILTVALKAFE
                     KHMGQGDKK"
     gene            3688..4422
                     /locus_tag="VQ865_001371"
     CDS             3688..4422
                     /locus_tag="VQ865_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000140960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3135701.1"
                     /translation="MTETLIKIENLHKSFGKNEVLKGINLEIKRGEVVVIIGPSGSGK
                     STLLRSMNLLEEATKGKVIFEGVDITDKKNDLFAMREKMGMVFQQFNLFPNMTVIENI
                     TLSPIKTKGESREVAEKRAQELLEKVGLPDKADAYPQSLSGGQQQRIAIARGLAMEPD
                     VLLFDEPTSALDPEMVGEVLAVMQDLAKSGMTMVIVTHEMGFAREVADRVIFMADGVV
                     VEDGTPEQIFEQTQEQRTKDFLSKVL"
     gene            4576..5433
                     /locus_tag="VQ865_001372"
     CDS             4576..5433
                     /locus_tag="VQ865_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HET3135702.1"
                     /translation="MTQIIDGKALAAKLQGQLAEKTAKLKEETALVPGLVVILVGDNP
                     ASQVYVRNKERSALAAGSRSEVVRVPETITQEELLDLIAKYNQDPAWHGILVQLPLPK
                     HIDEEAVLLAIDPEKDVDGFHPLNMGRLWSGHPVMIPSTPAGIMEMFHEYGIDLEGKN
                     AVVIGRSNIVGKPMAQLLLAKNATVTLAHSRTHNLAKVAAKADILVVAIGRAKFVTAD
                     FVKPGAVVIDVGMNRDENGKLCGDVDYEAVAPLASHITPVPGGVGPMTITMLMEQTYQ
                     AALRTLDRK"
     gene            5575..6447
                     /locus_tag="VQ865_001373"
     CDS             5575..6447
                     /locus_tag="VQ865_001373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000864675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HET3135703.1"
                     /translation="MKVINQTLLEKVIIERSRSSHKGDYGRLLLLGGTYPYGGAIIMA
                     ALAAVKSGAGLVTVGTDRENIPALHSHLPEPMAFSLQDQQLLKEQLEKAEVILLGPGL
                     RDDASGENLVKQVFVNLSQNQILIVDGGALTILARTSLSFPSSQLILTPHQKEWEKLS
                     GITIEKQKEDATASVLTSFPQGTILVEKGPATRIWEVGQSDYYQLQVGGPYQATGGMG
                     DTLAGMIAGFVGQFRQASLYERVAVATHLHSAIAQELSQENYVVLPTEISRYLPKIMK
                     IICQQDRVSKDKLV"
     gene            6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ865_001374"
     CDS             6729..7412
                     /gene="rpiA"
                     /locus_tag="VQ865_001374"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000429260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HET3135704.1"
                     /translation="MENLKKMAGIKAAEFVSDGMVVGLGTGSTAYYFVEEIGRRIKEE
                     GLQITAVTTSSVTTKQAEGLNIPLKSIDQVDFVDVTVDGADEVDSQFNGIKGGGGALL
                     MEKVVATPSKEYIWVVDESKLVEKLGAFKLPVEVVQYGAEQVFRHFERAGYKPSFREK
                     DGQRFVTDMQNFIIDLALDVIENPIAFGQELDHVVGVVEHGLFNQMVDKVIVAGRDGV
                     QISTSKKGK"
     gene            7426..8637
                     /locus_tag="VQ865_001375"
     CDS             7426..8637
                     /locus_tag="VQ865_001375"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HET3135705.1"
                     /translation="MSKFNRIHLVVLDSVGIGAAPDANNFVNAGVPDGASDTLGHISK
                     TVGLNVPNMAKIGLGNIPRETPLKTVAAESNPTGYATKLEEVSLGKDTMTGHWEIMGL
                     NITEPFDTFWNGFPEEILTKIEEFSGRKVIREANKPYSGTAVIDDFGPRQMETGELII
                     YTSADPVLQIAAHEDIIPLDELYRICEYARSITLERPALLGRIIARPYVGEPGNFTRT
                     ANRRDLAVSPFSPTVLDKLNEAGIDTYAVGKINDIFNGAGINHDMGHNKSNSHGIDTL
                     LKTMGLAEFEKGFSFTNLVDFDALYGHRRNAHGYRDCLHEFDERLPEIIAAMRENDLL
                     LITADHGNDPTYAGTDHTREYIPLLAYSPAFKGNGLIPVGHFADISATVADNFGVETA
                     MIGESFLDKLV"
     gene            8639..9181
                     /locus_tag="VQ865_001376"
                     /pseudo
     CDS             8639..9181
                     /locus_tag="VQ865_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398095.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1697 domain-containing protein"
     gene            9197..10006
                     /locus_tag="VQ865_001377"
     CDS             9197..10006
                     /locus_tag="VQ865_001377"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3135706.1"
                     /translation="MTFLNKIHETATFLKEKGIAAPEFGLILGSGLGELAEEIENPVV
                     VDYAEIPNWGRSTVVGHAGKLVYGELAGRKVLALQGRFHFYEGNPLEVVTFPVRVMKV
                     LGCEGVIVTNAAGGIGFGPGTLMAISDHINMTGQNPLMGENLDDFGPRFPDMSRAYTP
                     EYRATAHEVAKKLNIKLDEGVYIGVTGPTYETPAEIRSYKTLGADAVGMSTVPEVIVA
                     AHSGLKVLGISCITNFAAGFQEELNHEEVVEVTERVKGDFKGLLKAILAEL"
     gene            10482..11213
                     /locus_tag="VQ865_001378"
     CDS             10482..11213
                     /locus_tag="VQ865_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011681781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135707.1"
                     /translation="MLDSKEELKESENDAPKLETPLREEPRLAPQTLPEASEVLENKR
                     EESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGCYLAQIAEVEAYQKYPDF
                     YNHVLRKVTTFSAPKVITSRTVWNAKNGFWDVGLESRKLAVSGKIKHYVVDNDNVVTP
                     LIHNDRDIVTFTGNSRFKHRSRGYFESPMNDIPNFNIGKQATLDKHGYRDPKLDKVRF
                     FKKQALPRSSSQPSAEPMENIALGK"
     gene            11259..11462
                     /locus_tag="VQ865_001379"
     CDS             11259..11462
                     /locus_tag="VQ865_001379"
                     /inference="COORDINATES: protein motif:HMM:NF012956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="discoidin domain-containing protein"
                     /protein_id="HET3135708.1"
                     /translation="MDGKVDGNYGHNSVTHTNFQSKPWWQVDLAKEETIRQINIYNRT
                     DTAQDRLANFDVILLDSSGKEIE"
     gene            11487..11999
                     /locus_tag="VQ865_001380"
     CDS             11487..11999
                     /locus_tag="VQ865_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001275913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin"
                     /protein_id="HET3135709.1"
                     /translation="MSAQITINHKKARYVRIELEGYNALSLAEVEVFRFIATNGETAI
                     QVSKSVQPISQTPVKDKTLTIQHSGAYIARYSITWEEVTVDKDGNQVVRSHSWEGNGR
                     NQTAGFVLNLPIKENMRNLRVKIEKKTGLLWNRWQTIYENRPILAQPHRKITHWGTTL
                     NSKVSDDDVL"
     gene            12657..13367
                     /gene="deoD"
                     /locus_tag="VQ865_001381"
     CDS             12657..13367
                     /gene="deoD"
                     /locus_tag="VQ865_001381"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HET3135710.1"
                     /translation="MSIHIAAQQGEIADKILLPGDPLRAKFIAENFLGDAVCFNEVRN
                     MFGYTGTYKGHRVSVMGTGMGMPSISIYARELIVDYGVKKLIRVGTAGSLNEEVHVRE
                     LVLAQAAATNSNIVRNDWPQYDFPQIASFDLLDKAYHIAKELGMTTHVGNVLSSDVFY
                     SNYFEKNIELGKWGVKAVEMEAAALYYLAAQYHVDALAIMTISDSLVNPDEDTTAEER
                     QNTFTDMMKVGLETLIAE"
     gene            complement(13390..13914)
                     /locus_tag="VQ865_001382"
     CDS             complement(13390..13914)
                     /locus_tag="VQ865_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000684222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topology modulation protein"
                     /protein_id="HET3135711.1"
                     /translation="MKITIIGYSGSGKSTLAEKLSNYYSIPKLHMDTLQFQPGWQDSD
                     CEWMLTEIKNFLTKHKAWVIDGNYSWCYYQERMQEADQIIFLNFLPLTCLFRAFKRYL
                     KYRGKVRESMAADCPERFDWEFIRWILWDGRSKTQKENYQKLCQEYSHKVTILRNQRE
                     LDQFLDKKRKSYNS"
     gene            complement(13967..14203)
                     /locus_tag="VQ865_001383"
     CDS             complement(13967..14203)
                     /locus_tag="VQ865_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001274003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HET3135712.1"
                     /translation="MANIKSAIKRAELNVKQNEKNSAQKSAMRTAIKAFEANPSEELF
                     RAASSAIDKAETKGLIHKNKASRDKARLSAKLAK"
     gene            complement(14271..15191)
                     /locus_tag="VQ865_001384"
     CDS             complement(14271..15191)
                     /locus_tag="VQ865_001384"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HET3135713.1"
                     /translation="MTNEFLHFEKISRQTWQSLHRKTTPPLTEEELESIKSFNDQISL
                     QDVTDIYLPLAHLIQIYKRTKEDLAFSKGIFLQRESKSQPFIIGVSGSVAVGKSTTSR
                     LLQILLSRTFTDATVELVTTDGFLYPNQTLIEQGILNRKGFPESYDMEALLNFLDRIK
                     NGQDVDIPVYSHEVYDIVPEEKQSVKAADFVIVEGINVFQNPQNDRLYITDFFDFSIY
                     VDAGVDDIESWYLDRFLKMLSLAQNDPDSYYYRFTQMPIGEVEAFAHQVWTSINLTNL
                     QNYIEPTRNRAEVILHKSKNHEIDEIYLKK"
     gene            15389..15793
                     /locus_tag="VQ865_001385"
     CDS             15389..15793
                     /locus_tag="VQ865_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135714.1"
                     /translation="MKILIRYILELCFILSFALPFIKGANADNGICFVETYYGFTFLM
                     EHAIVTAVFIYSFLIAFLLKKRWAKWIAAGSYCFLVLWIATEGYFFRMSLEDLIRLWT
                     SLEILTQTYQLGFYLNILLGILLIIKYFKVKQ"
     gene            16009..16590
                     /locus_tag="VQ865_001386"
     CDS             16009..16590
                     /locus_tag="VQ865_001386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000289981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3135715.1"
                     /translation="MYYAENPDAAHDIHELRVELLGQKMTFLTDAGVFSKKIVDFGSQ
                     LLLKCLEVNQGETVLDVGCGYGPLGLSLAKAYGVQATMVDINTRALDLARRNAEKNNA
                     KATIFQSNIYEQVEGHFDHVISNPPIRAGKQVVHEIIEKSKDFLETGGDLTIVIQKKQ
                     GAPSAKSKMEDVFGNCEILKKDKGYYILRSVKE"
     gene            16587..17864
                     /locus_tag="VQ865_001387"
     CDS             16587..17864
                     /locus_tag="VQ865_001387"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001202959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HET3135716.1"
                     /translation="MRAVDLIQKKRDGQELTSSEIEWLVEGYVSGTVPDYQMSAFAMA
                     VYFKGMTTREISDLTMNMVKTGQEFDLSAIDGVKVDKHSTGGVGDKVTLILAPLVASF
                     GVPVAKMSGRGLGHTGGTIDKLESIKGYQVERSQEDFIRQVQDIGVSVIGQSDQLVKA
                     DKLLYALRDVTATVDTIPLIASSVMSKKIAAGADAILLDVTVGEGAFMKTVDEARELA
                     QTMVDLGKVVGRKTVAVITDMSQPLGRAIGNRLEILEALEILQGQGRQDITHFICELA
                     QIMLGLANVNKTVEEVHQHLENGQALAKFEEMVQAQGGDLEDLYRPVNVAHVVEIPAQ
                     ETGVISALPAMDFGLYAMRLGAGRAVKSDALDYETGIVFEKKIGDSVQKGEIVAKVYT
                     NEKIPPQLVTDFQKCVKISDEVKKIREIVEIIS"
     gene            17882..18544
                     /gene="deoC"
                     /locus_tag="VQ865_001388"
     CDS             17882..18544
                     /gene="deoC"
                     /locus_tag="VQ865_001388"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HET3135717.1"
                     /translation="MKLNKYIDHTLLKQDAKKKQIDSLLSEAREYDFASVCVNPTWVE
                     HAKKGLEGTDVKVCTVVGFPLGATTSAVKAFETKEAIQNGADEIDMVINVGALKSGNL
                     ALVESDIRAVVEASGDKLVKVIIEACLLTDQEKVVVCQLAQKAGADFVKTSTGFSTGG
                     ATIADVTLMRETVGSDMGVKAAGGARSYADALAFVEAGATRIGTSAGVAILKGELADG
                     DY"
     gene            18531..18920
                     /locus_tag="VQ865_001389"
     CDS             18531..18920
                     /locus_tag="VQ865_001389"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3135718.1"
                     /translation="MATTELIELAIETSKHAYVPYSHFPIGAVLVAKDGSVYTGVNIE
                     NASYPLTNCGERTAIFKAISEGQREFSELIVYGQTEKPISPCGACRQVMVEFFEQDLK
                     VTLVAKDKSTVEMTVGELLPYSFTDLN"
     gene            19011..20063
                     /locus_tag="VQ865_001390"
     CDS             19011..20063
                     /locus_tag="VQ865_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family protein"
                     /protein_id="HET3135719.1"
                     /translation="MNKKQWLGLGLVAVAAVGLAACGNRSSRNAASSSDVKTKAAIVT
                     DTGGVDDKSFNQSAWEGLQAWGKEHNLSKDNGFTYFQSTSEADYANNLQQAAGSYNLI
                     FGVGFALHNAVEEAAKEHTDLNYVLIDDVIKDQKNVASVTFADNESGYLAGVAAAKTT
                     KTKQVGFVGGIESEVISRFEAGFKAGVASVDPSIKVQVDYAGSFGDAAKGKTIAAAQY
                     AAGADIVYQVAGGTGAGVFAEAKSLNESRPENEKVWVIGVDRDQEAEGKYTSKDGKES
                     NFVLVSTLKQVGTTVKDISNKAEKGEFPGGQVIVYSLKDKGVDLAVTNLSEEGKKAVE
                     DAKAKILDGSVKVPEK"
     gene            20207..21742
                     /locus_tag="VQ865_001391"
     CDS             20207..21742
                     /locus_tag="VQ865_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000929819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135720.1"
                     /translation="MAHENVIEMRDITKVFGGFVANDKINLHLRKGEIHALLGENGAG
                     KSTLMNMLAGLLEPTSGEIAVNGQVVNLDSPSKAASLGIGMVHQHFMLVEAFTVAENI
                     ILGSELTKNGVLDIAGASKEIKALSERYGLAVDPSAKVADISVGAQQRVEILKTLYRG
                     ADILIFDEPTAVLTPSEIDELMAIMKNLVKEGKSIILITHKLDEIRAVSDRVTVIRRG
                     KSIETVEIAGATNADLAEMMVGRSVSFKTEKQASKPKEVVLSIKDLVVNENRGVPAVK
                     NLSLDVRAGEIVGIAGIDGNGQSELIQAITGLRKVESGSIELKGDSIVGLHPRQITEL
                     SVGHVPEDRHRDGLILEMMISENIALQTYYKEPHSKNGILNYSNITSYAKKLMEEFDV
                     RAASELVPAAALSGGNQQKAIIAREIDRDPDLLIVSQPTRGLDVGAIEYIHKRLIEER
                     DNGKAVLVVSFELDEILNVSDRIAVIHDGKIQGIVSPETTNKQELGVLMAGGNLGKEK
                     SDV"
     gene            21735..22793
                     /locus_tag="VQ865_001392"
     CDS             21735..22793
                     /locus_tag="VQ865_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135721.1"
                     /translation="MSKKLQQISVPLISVFLGILLGAIVMWIFGYDAIWGYEELFYTA
                     FGSLRGIGEIFRAMGPLVLIGLGFAVASRAGFFNVGLPGQALAGWILSGWFALSHPDM
                     PRPLMILATIVIALIAGGIVGAIPGILRAYLGTSEVIVTIMMNYIVLYVGNAFIHAFP
                     KDFMQSTDSTIRVGANATYQTPWLAELTGNSRMNIGIFFAIIAVAVIWFMLKKTTLGF
                     EIRAVGLNPHASEYAGISAKRTIILSMIISGALAGLGGAVEGLGTFQNVYVQGSSLAI
                     GFNGMAVSLLAANSPIGILFAAFLFGVLQVGAPGMNAAQVPSELVSIVTASIIFFVSV
                     HYLIERFVKPKKQVKGGK"
     gene            22796..23752
                     /locus_tag="VQ865_001393"
     CDS             22796..23752
                     /locus_tag="VQ865_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135722.1"
                     /translation="MSIITLLPLLVSSMLIYSAPLIFTSIGGVFSERGGVVNVGLEGI
                     MVMGAFSGVVFNLEFAEQFGAATPWLSLLVAGLVGSVFSIIHAAATVHFRADHVVSGT
                     VLNLMAPALAVFLVKVLYNKGQTDNLSQTFGRFDFPVLANIPVIGDIFFKSTSLLGYL
                     AIAFSFLAWFILFKTQFGLRLRSVGEHPQAADTLGINVYKMRYLGIIISGFLGGIGGA
                     IYAQSISVNFSVTTIVGPGFIALAAMIFGKWNPIGAMLSSLFFGLSQSLAVIGSQLPF
                     LQGVPAVYLQIAPYVLTILVLAAFFGKAVAPKADGINYIKSK"
     gene            23837..24519
                     /locus_tag="VQ865_001394"
                     /pseudo
     CDS             23837..24519
                     /locus_tag="VQ865_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         7182 a         4406 c         5573 g         7358 t
ORIGIN      
        1 atcataatgg acaaagggca agctgtcaag aaattacagt tattttagta aaaaaagaag
       61 cagaaaaatt tcattttcta ctccttttct ataggattta tttttctttt tcagaacttt
      121 taacttcagc ttttttggca gatttaatct gaatgtttcc cttgctagtc ataactgctt
      181 tgagatcttt ttcgcttgga ttttcaaggt agtagtcagt gattgtgtcc tcaatatagt
      241 cttgaatagt ccgacgaagt gggcgtgctc ccatttttgg atcataacct aggtcaacca
      301 acttttcctt gaccttgtca gttacatcca aacgaatgtt gttgctagag aggcgcttgt
      361 taacatctgc tagcatgagc tcgacaatct gaaggaggtt atccttgctg agagccttaa
      421 attcgataat gccatcaaaa cggttcataa actctgggct aaagaagtta ccgagttcac
      481 cgaggacaga attggtacgt ccttctctag cagcaccaaa tccaacgcta gcttcggtct
      541 ttcctgtacc tgcatttgag gtcatgataa tgatggcatc cttgaagcta acggtgcgtc
      601 cttgcccgtc tgtcaaacga ccatcgtcca agacttgaag aaacatgtgc ataacatctg
      661 ggtgagcttt ttccacttca tcgagaagga tgagagaata tggattgtgg cgaacttttt
      721 cagttaattg accagcctca tcatagccaa cataacctgg aggagcgccg accaacttag
      781 ccacactatg tttttccatg tattcactca tatcaaagcg aatcatacta tcagcagaac
      841 caaaaagttc gatagccagt tgtttggaaa gttctgtctt accgacacca gttggcccaa
      901 cgaagaggaa gcttccgatt gggcggttag gggtaccaag tccgacacga ttacggcgaa
      961 tagccttggc aatcttatcg actgcatcat cttggccaat aacatgagac ttgagatctt
     1021 cggctagatg gatgagttga gattgttctt tctctttcaa atcaccaaca gggatattgg
     1081 ttttctgctc gataatgtgc tcaatagttt tctcgctgat gataggagta tcctggtctg
     1141 tgatcttttt cttttgcatt tccttatact tggcaatctg gtcgcggaag taggccgcct
     1201 tctcaaaatc ttcttctcgt gtagcttgag acttgagatt ttcagcctca atcaagcgct
     1261 gatcaattac tttaggatcc acaaaattca aggtcaagtt catcttagaa ccagcttcat
     1321 ctaggaggtc aatggccttg tcaggcaaga agcgatcttg gatgtagcga ttggaaagag
     1381 ttgcagctgc ttcaatcgca gcatcggtat attgaacgtg gtggtaatct tcgtatttct
     1441 tttgaatccc tttgagaata gtgattgttt catccaccgt tggttcatcg actttaacag
     1501 gctgcatacg acgctcgagg gcagcatcct tttcaatgat acggtattca ttgagggtag
     1561 tagcaccgac tagttgcagt tctccacgag caagggctgg cttgaggata tttcctgcgt
     1621 ccatattacc atcactcgca gaaccagcac caacaatttc atggatttca tcgataaaga
     1681 ggatgatgtc ttcacgtttg cgaatttctt ccatgagttt ttgcatgcgt tcttcaaatt
     1741 gtcctcgaat ccccgttcct tgaactaagc taaccacatc cagacggatg acttgtttac
     1801 cttggagttt atgtggcaca tcgccatcga caattttctg agctagacct tcgacaacgg
     1861 ccgtttttcc gacaccaggt tcaccgataa ggacaggatt attcttcgtt ctacgattga
     1921 gaatctcgat gacacggata atctcatcgt cgcgcccaat aacggggtca atgtctccac
     1981 gacgggcaat ttcagttaca ttaataccaa attcttccag caggcctttt tcttggctag
     2041 gtggcggagt ttgagcagat ccacgatttt gggaaccata accgccgttt ccaccgtaac
     2101 ctccacctga ttgggttggg ggaataggag gagtattgct agaaggtctg aaattgttta
     2161 gatcattgaa gaaatcacca aagggatcga agtcacgatt gttcagatcc gtcatacctt
     2221 tgaagaggct attgttagga tctgttttga taatcttata gcagttttga cagaggtcaa
     2281 tttgtttttg ttttccattg agattggtgt aaagatgaat tgttgagtcg ttaattttac
     2341 agttttgaca aagcatacat ctacctcatt tctttcttta gcctgacttg tttaaaggtc
     2401 aaaaatagtc aaattctata ctctcattat aacaggattg gggtgtaaag caagtaaaaa
     2461 gattgaagct ttgagaagtt gttacaatga aaatttttgt gaatttggac tataaaaaaa
     2521 tcctatttgt gagacaaaaa ggattttact tagacatgca gggacaatcc cagcttgttt
     2581 tagattagta gagaagttcg taaatttcca ttgcgattaa gtcaatgcta tcaaacgtat
     2641 acgtttcgcg atcttctacg tcacgaaggg taaagattgg gccgttttct tcgtcgtggc
     2701 tgtacgcaac ttctgcaaca acaactcctt cgcgttcaaa attacgtttt aaatttccgc
     2761 catcgtttgc cattgcttca aggcggttga tgattctaac caaatgtgat tccattttga
     2821 ttctccttca tttcttatcg ttactatttt accataaagg aggccaactt gactagaaaa
     2881 aactaagatt tctcgctaat tctgctagtt taaagatttt taaataaatt ggataaaaaa
     2941 tttaaatttt aattcaaaac atgttataat catacagtat tctattttag aaagcagtgt
     3001 gactatgaat ttttcttttt tacctaagta tttaccttat tttaactatg gggctgttgt
     3061 gacgattctt atttctatct gtgttatctt tttgggaact attttgggtg ttgtcttggc
     3121 ttttgggcaa cgttcaaagt ttaaaccgct tgtttggttg gccaacttgt acgtttggat
     3181 tttccgtggg acaccgatga tggttcaaat tatgattgcc tttgctctta tgcatatcaa
     3241 tgctccgact attcagattg gaattttagg tgttgatttt tcgcgtctga ttccagggat
     3301 tttgattatc tctatgaata gtggtgctta tgtttcggag actgttcgtg ccggaatcaa
     3361 tgcggttcca aaaggtcagc tagaggcggc ttattcgcta gggattcgtc ctaaaaatgc
     3421 gatgcgttat gtgattttgc cacaagcaat caaaaatatc ttgccagcat tggggaacga
     3481 atttatcacc attatcaagg acagctccct cttatcagct attggggtca tggagttgtg
     3541 gaatggggct acaacagttt ctacaacaac ctatctacct ttaacaccgc ttttatttgc
     3601 agcattttat tacttgatta tgacctctat tctgacagta gccttgaaag cttttgaaaa
     3661 acatatggga caaggagata agaaataatg acagaaacct tgataaaaat tgaaaattta
     3721 cataaatctt ttggaaagaa tgaagtattg aagggaatca acctcgagat taaaagagga
     3781 gaagttgtcg ttatcatcgg tccttcaggg agtgggaaat ctaccttgct tcgctctatg
     3841 aatttgttgg aggaagcaac caaggggaag gttatctttg agggagtcga tattacggac
     3901 aagaagaatg acttgtttgc catgcgtgag aagatgggca tggttttcca acaatttaac
     3961 ctctttccta atatgactgt gattgaaaat attaccttgt cacctatcaa gaccaaaggt
     4021 gaaagcaggg aagttgctga gaagagagcc caagagcttt tggaaaaagt tggtttgcca
     4081 gataaggcag acgcttatcc acagagtctg tcgggtgggc agcaacaacg gattgccatc
     4141 gcgcgtgggt tggctatgga accagatgtt ttgctctttg acgaaccaac ttcagccttg
     4201 gatcctgaaa tggtaggtga ggtattggct gttatgcaag accttgccaa gtcagggatg
     4261 actatggtta tcgtaacaca tgagatggga tttgcccgtg aggtggcaga tcgtgttatc
     4321 tttatggcag acggtgtggt tgttgaagat gggacacctg agcagatttt tgaacaaacc
     4381 caagaacaac ggactaaaga tttcttgagt aaggttttat aatctatttt aaaatttcaa
     4441 gacaagatta gtgaaaagtt caaccagagc tttttcttat agtttgaaac tataggataa
     4501 cctaggaaag aagtgttaga gggcactagc agtttttggt ataatggaag atatttgaaa
     4561 gaaaagagaa gtgatatgac acagattatt gatgggaaag ctttagcggc caaattgcag
     4621 gggcagttgg ctgaaaagac tgcaaaatta aaggaagaaa cagctctagt gcctggtttg
     4681 gtagtgattt tggttgggga taatccagcc agccaagtct acgttcgcaa caaggagagg
     4741 tcagctcttg cggctggttc ccgtagcgaa gtagtgcgag ttccagagac cattactcaa
     4801 gaggaattgt tagacctgat tgctaaatat aatcaggatc cagcttggca tgggattttg
     4861 gtccagttgc cattaccaaa acatatcgat gaagaggcgg ttttattagc cattgaccca
     4921 gaaaaggatg tggatggttt ccatccccta aacatgggac gtctttggtc tggacatcca
     4981 gtcatgattc cctcgacacc tgcaggaatt atggaaatgt ttcatgaata tgggattgac
     5041 ttggaaggta aaaatgcggt cgtaatcggt cgttcaaata tcgttggaaa acctatggct
     5101 cagcttcttt tggctaaaaa tgcgacagta accttggccc actcacgaac tcataatctt
     5161 gccaaggtgg ctgctaaagc agatattctt gtagtcgcaa tcggccgcgc caagtttgtg
     5221 actgctgact ttgtcaaacc aggtgcggtt gtcattgacg ttgggatgaa ccgagatgaa
     5281 aatgggaagc tctgtggaga tgttgattat gaggcagttg caccacttgc tagccatatc
     5341 acgccagtcc ctggaggtgt cggtcctatg accattacca tgctgatgga gcaaacttat
     5401 caagcagcac ttcggacatt ggatagaaaa taagagaaac attcgattaa tagagtgtat
     5461 tttctatagc tatatctaaa atggcagaaa tgaatattaa attttagata taagattaca
     5521 aaaggaggtc tgcgtctcct ttttgttgta taataaaagt gagagggaaa aaggatgaaa
     5581 gtgattaatc aaaccttact agaaaaagtt attattgaac gttctcgttc aagtcataaa
     5641 ggagattatg gtcgtctgct gctgcttggt ggtacttatc cttatggagg tgccatcatc
     5701 atggctgctt tagcagctgt aaaaagcggt gcaggattgg tgaccgttgg aacggacagg
     5761 gaaaatatcc cggctctgca cagccattta cctgagccta tggccttttc tcttcaagac
     5821 cagcaattgt taaaagagca attggagaag gcagaagtta tcttgctggg gcctggttta
     5881 cgagacgatg cttctggaga aaatctagta aaacaggtct ttgttaattt aagccaaaat
     5941 cagattttga ttgtagacgg aggtgccttg accattcttg ctaggacaag tttgtcattt
     6001 ccctcaagcc agcttatcct aactcctcac caaaaagaat gggaaaaatt atctggaatt
     6061 acgattgaaa agcaaaagga agatgcaacg gctagtgttc tgacttcctt ccctcaagga
     6121 acaattttgg tggagaaagg cccagctact cgtatttggg aagttggcca atctgattat
     6181 taccagttac aggttggtgg tccttatcag gcgactgggg gaatgggaga tactctggct
     6241 gggatgatcg caggatttgt aggccaattc cgacaggcca gtctctacga gcgtgtggca
     6301 gtagcgaccc atcttcattc agccatagcc caagaactat ctcaagaaaa ttatgtggtc
     6361 ttaccgacgg aaatcagcag gtatcttccc aaaataatga aaattatttg tcaacaagat
     6421 agggtaagca aagataaact tgtttaaaat agacagataa atctacttcc ttctcttaat
     6481 ttatgattct tgaaatgcgc ctgctttaag gctaaactag acgtatcaaa gttaagagtt
     6541 tgtttttgta actggaatga gatgaacaaa tcaaatacat aaaagataaa ctcattttta
     6601 ttcgtttggt aaaaataaaa tgcatatttt taaagaaaga ttgatgaaaa atgtagattt
     6661 gatgttttta cttgaataaa aagcggtttc atagtaaaat aagaactgag aatgatggag
     6721 gtaaatcggt ggaaaatctg aagaaaatgg caggtatcaa ggctgctgag ttcgtgagcg
     6781 atggaatggt cgttggactt ggaacaggct cgactgccta ttattttgtc gaagaaatcg
     6841 gtcgtcgtat caaggaagaa ggattgcaga ttacagctgt aacaacttct agtgtgacca
     6901 ctaaacaggc agaaggcctt aatatcccgc tcaagtctat tgaccaagta gactttgtcg
     6961 atgtgacggt tgatggcgcg gatgaagtgg atagtcagtt taatggaatc aaaggcggtg
     7021 gtggtgccct tctcatggaa aaggtggtcg caacaccatc aaaagaatac atttgggtgg
     7081 tggatgaaag caagctggtc gaaaaactag gtgcttttaa attgccagta gaagtggttc
     7141 agtatggtgc agagcaggtc tttcgtcatt ttgaacgagc tggctacaaa ccaagtttcc
     7201 gtgaaaaaga cggccaacgt tttgtgacgg atatgcagaa ttttatcatt gacctcgcct
     7261 tggatgtcat tgaaaatcca attgcttttg gacaagaatt ggaccatgtc gttggtgttg
     7321 tggagcatgg tttattcaac caaatggtgg ataaggtaat cgttgctgga cgagatggag
     7381 ttcagatttc aacttcaaaa aaaggaaaat agaagggggc ataagatgtc taaatttaat
     7441 cgtattcatt tggtggtact ggattctgta ggaatcggtg cagcaccaga tgctaataac
     7501 tttgtcaatg caggggttcc agatggagct tctgacacac tgggacacat ttcaaaaaca
     7561 gttggtttga atgtcccaaa catggctaaa ataggtcttg gaaatattcc tcgtgaaact
     7621 cctcttaaga ctgtagcagc tgaaagcaat ccaactggat atgcaacaaa attagaggaa
     7681 gtatctcttg gtaaggatac tatgactgga cactgggaaa ttatgggact caacattact
     7741 gagcctttcg atactttctg gaacggattc ccagaagaaa tcctgacaaa aatcgaagaa
     7801 ttctcaggac gcaaggttat tcgtgaagcc aacaaacctt attcaggaac ggctgttatc
     7861 gatgattttg gaccacgtca gatggaaact ggagagttga ttatctatac ttcagctgac
     7921 cctgttttgc agattgctgc ccacgaagac attattcctt tggatgaatt gtaccgtatc
     7981 tgtgaatacg ctcgttcgat tacccttgag cgtcctgccc ttcttggtcg catcattgct
     8041 cgcccttatg taggtgaacc aggtaacttc actcgtacgg caaaccgtcg tgacttggct
     8101 gtatctccat tttccccaac tgttttggat aaattgaatg aggctggtat cgatacttat
     8161 gctgtgggta aaatcaacga tatctttaac ggtgctggta tcaaccatga catgggtcac
     8221 aacaagtcaa atagtcatgg aattgataca ctattgaaga ctatgggact tgctgagttt
     8281 gaaaaaggat tctcattcac aaacctagtt gactttgatg ccctttacgg ccatcgtcgt
     8341 aatgctcacg gttaccgtga ttgcttgcat gagtttgatg aacgcttacc tgaaattatc
     8401 gcagctatga gagagaatga ccttctcttg attactgcgg accatggaaa tgacccaacg
     8461 tatgcaggaa cggatcacac tcgggaatat attccattgt tggcctatag ccctgccttt
     8521 aaaggaaatg gtctcattcc agtaggacat tttgcagata tttcagcgac tgttgccgat
     8581 aactttggtg tggaaactgc tatgattggg gaaagtttct tagataaatt ggtataagat
     8641 gacgcgctat gctttgctgg tgagaggtat caatgttggt ggtaagaata aggtcgtcat
     8701 ggcggaactt cgtcaagaat tgacaaactt gggactggaa aaggttgaga gctacatcaa
     8761 cagtggcaat attttcttta cttcgataga ttccaaagcc caattggttg aaaagctaga
     8821 gactttcttt gcagtccatt atccatttat tcagagcttt tctttactga gtctagagga
     8881 ctttgaggcg gaacttgaaa atctaccagc ttggtggagc agagacttgg cacgaaaaga
     8941 ttttctcttt tacactgagg gtttggatgt ggaccaagtc atcgcgacag ttgaaagttt
     9001 agagctgaaa gatgaagtgc tttattttgg aaaacttggg attttctagg ggaaattttc
     9061 tgaagaatcc tattctaaga ctgcctatca taagtacttg ctgaaggtgc ctttctaccg
     9121 ccacattact attcgtaatg ctaaaacctt tgacaaaatt ggtcaaatgc taaaaaaata
     9181 ataaaggaga cacacaatga catttttaaa caaaatccat gaaactgcta ctttcctgaa
     9241 agaaaaggga attgcagccc ctgagttcgg tctaatcctt ggatcaggac ttggagaatt
     9301 ggcagaagaa atcgaaaatc cagttgtagt agactatgct gagattccaa actggggccg
     9361 ttcaacagta gtcggtcatg ctggtaaatt ggtatatggt gaactggcag gtcgcaaggt
     9421 cttggctctt caaggtcgtt tccatttcta tgaagggaat cctctggaag tggtgacttt
     9481 cccagttcgt gtgatgaaag ttcttggatg tgaaggtgtt attgtaacca atgcagctgg
     9541 cggtatcgga tttggtcctg gtaccttgat ggctatctca gaccatatca acatgacggg
     9601 gcaaaatcca ttgatgggtg aaaacttgga tgactttggc ccacgtttcc cagatatgtc
     9661 tagggcctac acaccagaat accgtgccac tgcccatgaa gtggctaaaa aacttaatat
     9721 caagcttgat gaaggtgtct atatcggagt tactggtccg acttatgaaa caccagcaga
     9781 aattcgttcc tataagacac tgggagcaga tgcagttggt atgtctacgg ttcctgaagt
     9841 tatcgtggca gcccactctg gcttgaaagt tctgggaatt tcatgtatca ctaactttgc
     9901 ggctggtttc caagaagaac tcaatcacga agaagttgta gaagtgactg aacgtgttaa
     9961 aggtgatttc aaaggcttgc ttaaagcgat tcttgctgaa ttgtaagaaa aaagatttaa
    10021 aagggggagt gcctctgtct tttcaggatt gactgcctat ccgtattaaa gaagaaacag
    10081 aggaatacta tgagcttctt cctgctctta taactgaaag aagcggaaga ataggtatgt
    10141 ctgatctgat agccagcatt gtgaaagaca agattctagg atactagcat tagcttccta
    10201 gccaagcaga ctagtatgat aaggagagat gagaatgaat tgactttctg aatttctcag
    10261 tcttatcata tatagcacaa tgagatttcg cttgagtctg cttgtaaata aacgaaaaga
    10321 aagataagaa ataatgaaaa ttggtcaacg aattatgcgc tttggcataa aaaattaagt
    10381 atcggagttg tatctgttgt agtcggcttt gatttctagc tccagctgga atttcagcca
    10441 atgaagtaaa gcaagatgta acatctgaag tggtaatagg tgtgctagat tctaaggagg
    10501 aattgaaaga gtcagaaaat gatgctccaa aactagaaac tcctcttaga gaggagccaa
    10561 gactagctcc tcaaacgctt ccggaagcaa gtgaagttct tgaaaacaaa agggaagagt
    10621 caaaagtaga gataacagag ccagctcaag cggatgatat ccgcaaggtt gttggggaat
    10681 tagccaagga tataagtatt actaagttgt atatgacagg tcattctctt ggatgctacc
    10741 tagctcagat tgcagaggtt gaagcttacc aaaaatatcc tgatttttat aaccatgtat
    10801 tgaggaaagt gacaactttc agtgctccta aagtgattac ttccagaact gtttggaatg
    10861 ctaagaatgg tttctgggat gttggtttgg aaagtcgtaa attagctgtt agtggaaaaa
    10921 ttaagcatta tgtggttgat aatgacaatg ttgtgactcc cttgattcat aatgatcgtg
    10981 atattgttac atttacaggt aattcacgct ttaaacaccg ttctcgtggc tattttgaaa
    11041 gtccaatgaa tgatattcct aactttaata ttggtaaaca agctaccttg gataaacatg
    11101 gttatcgtga tccgaaattg gataaagtgc gattctttaa gaaacaggct ctgcctcgat
    11161 cttctagtca accaagcgct gaaccaatgg aaaatattgc cttaggaaaa taggttactc
    11221 aaagttcgac agctttcgga ggagatgcta gaagagctgt ggatggcaaa gtcgatggta
    11281 actatggtca caattctgtc actcatacaa actttcaatc taagccttgg tggcaagtag
    11341 atttggctaa agaagaaacc attcgccaaa tcaatattta caaccgaaca gacactgccc
    11401 aggatagatt ggcaaacttt gatgtcattc ttttagacag ttctggtaaa gaaattgagt
    11461 gaaaacgtat aacatctcct aaagatgtgt cagcacaaat tacgattaac cataaaaaag
    11521 cgcgctatgt tcggattgag ctagaaggct ataatgccct cagtcttgca gaagttgaag
    11581 ttttccgctt tatagctacg aatggtgaaa cggcgataca agtttctaag tcagttcaac
    11641 caatcagtca gactcctgtg aaggataaaa cattgacaat tcaacacagt ggagcttaca
    11701 ttgcccgcta ctccataact tgggaagaag ttacagtaga taaagatgga aaccaagttg
    11761 ttcgtagtca ttcttgggaa ggaaacggtc gcaaccagac tgcaggtttt gtcctcaacc
    11821 tcccaatcaa agaaaatatg agaaatctgc gagttaagat tgagaaaaag acgggcctac
    11881 tatggaatag atggcaaaca atctatgaaa acagaccaat tttagctcaa ccccaccgta
    11941 aaattaccca ttggggtacg acattgaatt ccaaggtgag tgacgatgat gtcttgtaat
    12001 ctgatggtac aatgatagtt agtttgtcta gtttataaga aagtactacc tgagcttgaa
    12061 taggactcag gtagctctct gtgaaagaac aaaattaata ctcaatgaaa atcaaagagc
    12121 aaactaggaa actagccgca ggttgctcaa agcactgctt tgaggttgta gataagactg
    12181 acgaagtcag tcacatatat aatccaaggc gacgttgacg tggtttgaag agattttcga
    12241 agagtataaa cagaaaggta gagcgcgtgt tctaatttga acacgagtag aaaacttttc
    12301 taaaaataaa aacgaaagga tgggtaaact gtattcgctg aactgaatac gggcgactct
    12361 cctctaaatc aaaattaaga aagaaaggaa ttgaccccac cctaaaagca gtgggaaaaa
    12421 gatagttggt ctagcgagca tcgctcactg cgcccaactc ctattttccc ttcgcttttt
    12481 gatgggtttg gtatctttct caatataaaa tataaaataa agaaaggtag agcgtgtgtt
    12541 ttgatttgaa cacgagcgga aaactcggaa aatagataat ctgactgaaa aatcaggatt
    12601 tctcgtcagg ttcctaattt tcagtcgttt tcttctcgct ctttgtatca taaattatgt
    12661 ctatccatat tgctgctcag cagggtgaaa ttgctgataa aattcttctt cctggggatc
    12721 ctcttcgtgc taagtttatt gcggagaatt tccttggtga tgctgtttgt tttaacgaag
    12781 tgcgtaacat gtttggttac actggtactt acaagggtca ccgtgtatct gtcatgggaa
    12841 ctgggatggg aatgccatct atttcgattt atgcgcgtga gttaatcgta gactacggtg
    12901 tgaagaaatt gattcgtgtg ggaactgcag gttctttgaa tgaagaggtt catgttcgtg
    12961 aattagtttt ggcgcaggcg gctgcaacca actcaaacat cgttcgtaat gactggccac
    13021 agtacgattt tccacaaatt gctagctttg atttgcttga taaagcctac catatcgcca
    13081 aagaacttgg tatgactact cacgttggga acgttttgtc atctgatgtc ttttactcaa
    13141 attactttga aaagaatatc gagcttggta aatggggagt caaggctgtg gaaatggaag
    13201 cagcagctct ttactatctt gctgcccaat accatgttga tgcgctagct atcatgacca
    13261 tctctgatag cttggtcaat ccagacgaag acacaactgc agaagaacgt caaaatacct
    13321 tcactgatat gatgaaggtt ggtttggaaa ccttgattgc agaataatta tagccaaaaa
    13381 ggaagccctt tatgaattgt aggacttcct tttcttatcc agaaattgat ctagctctct
    13441 ctgatttcga agaatagtga ctttatgtga atattcttgg caaagttttt ggtaattttc
    13501 tttttgagtt ttgctacgcc catcccaaag aatccatctg ataaactccc agtcaaagcg
    13561 ttcagggcaa tctgccgcca tactttctct gacttttcca cggtatttaa gataacgctt
    13621 aaaggctcta aagagacagg tcaatggcaa aaaattgaga aagatgattt ggtcagcttc
    13681 ttgcattcgt tcttggtagt agcaccaaga ataattacca tcgatgaccc aagctttatg
    13741 cttggtgaga aagtttttta tctcggttaa catccattcg cagtcactgt cttgccaacc
    13801 aggttgaaat tggagtgtgt ccatgtgcag ttttggaatg gagtagtagt tagataactt
    13861 ttctgctaga gttgacttac cagaaccaga atatccgata attgtgattt tcattttcta
    13921 ccttttccta tttggagaca aaaaaacagc ctctatggac tgtttcttat ttagcaagtt
    13981 tagctgaaag acgagcttta tcgcggcttg ctttgttttt gtgaatcaaa cctttagttt
    14041 ctgctttatc gatagctgag ctagcagcac ggaaaagttc ttcagatggg tttgcttcga
    14101 aagcttttat agcagtacgc atagctgatt tttgagctga gttcttttcg ttttgtttaa
    14161 cgttcaattc agcgcgtttg atagctgatt taatgtttgc caatgttctt acctccatat
    14221 ttactaacta taccattata tatgaaaact tacgttttga caagggaaaa ttattttttt
    14281 aagtaaattt catcgatttc atggttcttg cttttatgaa gaatcacttc tgcacgattt
    14341 ctggttggtt caatataatt ttgtagattt gtgagattga tactggtcca gacctgatgg
    14401 gcaaaggctt ccacttcccc aatcggcatc tgagtaaaac gataatagta gctatcaggg
    14461 tcgttttggg ctaggctcag cattttcaag aaacggtcca gataccaact ttcaatatca
    14521 tccactccag catctacata gatggaaaag tcaaagaagt cagtgatata gagacgatcg
    14581 ttttgtggat tttgaaagac attgattccc tcaacaatta caaaatcagc agctttgaca
    14641 ctttgtttct cttcgggtac gatgtcgtaa acttcatgag aatagacagg aatatctaca
    14701 tcttgtccat ttttgatgcg gtccaagaag ttgagaagag cttccatatc atagctttca
    14761 ggaaatcctt tacgatttaa aatcccctgc tcaatcaagg tttgattggg atagagaaaa
    14821 ccatcagttg taaccaactc aaccgtagca tctgtaaacg tacgggacag taggatttga
    14881 agtaggcgac tggttgtgga ttttccaacg gcaacactcc cagaaacccc aataataaaa
    14941 ggttgagatt tactttcacg ttggaggaaa attccttttg aaaaggctaa atcttcctta
    15001 gttcgcttgt aaatctgaat cagatgagcc aaggggagat agatatctgt aacgtcttgg
    15061 agactgattt ggtcattaaa actcttgata gattccaatt cttcttctgt caaaggaggt
    15121 gttgtctttc gatgtaaaga ttgccaagtc tggcggctga ttttttcaaa atgtaaaaat
    15181 tcgttggtca tttgttttcc cctagatatt ttgtctatca taccataaaa atctaaaaaa
    15241 ataaagcggt ttcttgaatg tggtaagtca atggtatata gtataagtga tcaatttatt
    15301 gatgaaatag gagatagatt ctactgattt ataagtttat aagcttataa agggggcttt
    15361 ttagttcaca acttatagga ggtgtactat gaaaatctta atacgttaca tattggaact
    15421 ctgttttatt ttaagttttg ctttaccttt tataaaagga gccaatgcag ataatggtat
    15481 atgctttgtg gaaacctatt acggttttac ttttttgatg gaacatgcta ttgtaacagc
    15541 tgtctttatc tattcgtttt taattgcttt cttactaaaa aaacgatggg cgaaatggat
    15601 tgctgctggt agttattgct ttttagtcct atggattgcg acagagggtt atttcttccg
    15661 catgtcacta gaagatttga tacgactttg gacaagtttg gaaatcctga cacaaacgta
    15721 tcagttgggc ttttatctaa acattttgtt aggaattttg ttgataataa agtattttaa
    15781 ggttaagcaa tagaaataat aatctgcctg attatagatg ataaactttt tgtttttatc
    15841 tggactgtga tatttatagt tctaaatggt ttattattta taagtgttga aagagattga
    15901 agaaaaaggc ttcgtgactt gctttcttcg gtctttttcg ttttattatc aatttgtaaa
    15961 cgatttacaa tttgagtcaa attatggtaa aatagtgtca tgagtaaaat gtattatgca
    16021 gaaaatcctg acgctgctca cgacattcat gagttgagag tagagttgtt gggacaaaaa
    16081 atgacctttt taacggatgc gggtgttttt agcaagaaaa tagttgactt tggaagtcaa
    16141 ctattgctca agtgtcttga ggtcaaccaa ggagaaactg tccttgatgt aggctgtggt
    16201 tacggacctt tgggtttgtc cttagctaag gcttatggag ttcaggctac tatggttgat
    16261 atcaacactc gtgccttgga tttagctcgg agaaatgctg aaaaaaataa tgcaaaagcg
    16321 acgattttcc agtccaacat ctatgaacaa gttgaaggac attttgatca tgtcatttcc
    16381 aatcctccta tccgtgcggg caagcaagtc gttcatgaaa tcattgagaa aagtaaagat
    16441 ttcttggaaa ctggtgggga tttgacaatc gtcatccaga aaaaacaagg ggctccaagt
    16501 gctaagtcca agatggagga tgtgtttggt aattgtgaaa tccttaaaaa agacaaggga
    16561 tactatatcc ttagaagtgt gaaagaatga gagcagttga tttaatacaa aaaaaacgag
    16621 acggtcaaga actgacttca agtgaaattg aatggctggt agaaggctat gtgtcaggaa
    16681 ctgttcctga ttatcagatg tctgcctttg ctatggctgt ttattttaaa ggaatgacga
    16741 ctcgtgaaat ttctgattta acgatgaata tggttaagac tgggcaagag tttgacctgt
    16801 cagccattga tggtgtgaaa gttgacaagc attctactgg tggtgtcggc gataaggtaa
    16861 ccttgatttt agctcctctt gttgctagct tcggtgtgcc tgtagcaaaa atgagtggtc
    16921 gtggtcttgg ccatacaggc ggaacaattg ataaattgga gtccattaag ggctatcaag
    16981 tagaacgtag tcaagaggat tttattcgtc aggttcagga tattggagta tctgtcattg
    17041 ggcaatcaga ccagctggtc aaagcagata agcttctcta tgcccttcgt gatgtgaccg
    17101 caactgtcga cacgattcct ttgattgcga gttcggtgat gagcaagaaa attgcggcag
    17161 gggcggatgc tattttgcta gacgtgactg tcggtgaggg tgccttcatg aagacggttg
    17221 atgaggcgcg tgagttggct caaactatgg tagatcttgg taaggttgtt ggacggaaga
    17281 cagtagcagt gattacggat atgagccagc ctttgggacg agcgattgga aatcgtctgg
    17341 aaatccttga agcattggag attttgcaag gtcaaggacg tcaggatatt acccacttta
    17401 tttgtgaatt ggctcaaatt atgcttggtt tggcaaatgt taacaaaact gttgaagaag
    17461 ttcaccaaca tcttgagaat ggtcaagcac tggctaagtt tgaggaaatg gtgcaagccc
    17521 aaggtggaga cttggaagac ctctatcgtc ctgtaaatgt agctcatgtg gtggaaatcc
    17581 ctgctcagga aacgggtgtc atttcagctc ttccagctat ggactttggt ctttatgcca
    17641 tgaggctggg tgctggtcgt gcagttaagt ctgatgcctt ggactatgaa acaggaattg
    17701 tttttgaaaa gaagattgga gactccgttc aaaagggtga aattgttgca aaagtataca
    17761 caaatgaaaa aattccacct caactagtta cagatttcca aaaatgtgtt aaaataagtg
    17821 atgaagtgaa aaaaatccgt gaaattgtag aaatcatctc ctaaatggag ggaaaaccga
    17881 aatgaaatta aataaatata tagatcatac gcttttaaaa caagatgcaa agaaaaaaca
    17941 aattgatagt ttgttgtctg aggctagaga gtatgacttt gccagtgttt gcgttaatcc
    18001 gacctgggtt gaacatgcta aaaaaggact tgaaggcaca gatgttaagg tttgcacagt
    18061 agtaggtttc cctttgggag caacaacttc agccgtgaaa gcatttgaga caaaagaagc
    18121 tatccaaaat ggtgcagatg agattgatat ggtgatcaat gttggagctc tcaaatcagg
    18181 taatttagcc ttggttgagt cagatattcg cgcagtagtg gaagcaagtg gtgataagtt
    18241 agtgaaagtc attattgaag cttgccttct gacagaccaa gaaaaagttg ttgtttgcca
    18301 attggcccaa aaagctgggg ctgactttgt caaaacatct actggctttt caactggtgg
    18361 tgctacgata gcagatgtta cattaatgcg tgaaacagtt ggatctgata tgggtgtcaa
    18421 ggccgccggt ggagctcgtt cttatgcaga tgctcttgcc tttgtcgaag caggtgcgac
    18481 ccgtatcgga acgtcagctg gggtagctat tttaaaagga gaattggcag atggcgacta
    18541 ctgagttgat tgaactggca attgaaacca gcaaacatgc ctatgtcccc tattctcact
    18601 ttcctatcgg agcagtttta gtagctaaag acggaagtgt ttacacggga gtgaatattg
    18661 aaaatgctag ctatcctttg accaattgcg gtgagagaac agctattttt aaggctatat
    18721 ctgaaggcca aagagaattt tcagaattga ttgtctatgg tcaaactgaa aaaccgattt
    18781 caccatgtgg tgcttgtcgc caagtaatgg tcgaattttt tgaacaagat ttaaaagtga
    18841 ccttagtcgc aaaagataaa tcgacggtcg agatgacggt cggggagtta cttccatatt
    18901 cttttacaga cttaaattag tctgagtcgc tctttgagtg gcaagggtct ttgtgaccaa
    18961 tcaatccata cttgcaacat cgttgcacat cttatttagg aggttcagta atgaacaaga
    19021 aacaatggct aggtcttggc ctagttgcag tggcagcagt tggacttgct gcatgtggta
    19081 accgctcttc tcgtaacgca gcttcatctt ctgatgtgaa gacaaaagca gcaatcgtca
    19141 ctgatactgg tggtgttgat gacaaatcat tcaaccaatc agcttgggaa ggtttgcagg
    19201 cttggggtaa agaacacaat ctttcaaaag ataacggttt cacttacttc caatcaacaa
    19261 gtgaagctga ctacgctaac aacttgcaac aagcggctgg aagttacaac ctaatctttg
    19321 gtgttggttt tgcccttcac aatgcagttg aagaagcagc taaagaacac actgacttga
    19381 actatgtctt gattgatgat gtgattaaag accaaaagaa tgttgcgagc gtaactttcg
    19441 ctgataatga gtcaggttac cttgcaggtg tggctgcagc aaaaacaact aagacaaaac
    19501 aagttggttt tgtaggtggt atcgaatctg aagttatctc tcgttttgaa gcaggattca
    19561 aggctggtgt tgcgtcagta gacccatcta tcaaagtcca agttgactac gctggttcat
    19621 ttggtgatgc ggctaaaggt aaaacaattg cagccgcaca atacgcagcc ggtgcagata
    19681 ttgtttacca agtagctggt ggtacaggtg caggtgtctt tgcagaggca aaatctctca
    19741 acgaaagccg tcctgaaaat gaaaaagttt gggttatcgg tgttgaccgt gaccaagaag
    19801 cagaaggtaa atacacttct aaagatggca aagaatcaaa ctttgttctt gtatctactt
    19861 tgaaacaagt tggtacaact gtaaaagata tttctaacaa ggcagaaaaa ggagaattcc
    19921 ctggcggtca agtgatcgtt tactcattga aggataaagg ggttgacttg gcagtaacaa
    19981 acctttcaga agaaggtaaa aaagctgtcg aagatgcaaa agctaaaatc cttgatggaa
    20041 gcgtaaaagt tcctgaaaaa taatggatgg aagtcatttc ttaggaagcg gccaagggcc
    20101 gcttttttaa gagttgagac aaagtcattt tgtctcagta aagcttgcta ctagacaaac
    20161 tagcaagttt tattgaaata aaataagact ctgaaaggaa gagcacatgg cacacgaaaa
    20221 tgtcattgag atgcgtgata ttaccaaggt gtttggtgga tttgttgcca acgacaaaat
    20281 caacttgcac ctacgaaaag gtgaaattca tgcactttta ggagaaaatg gggctggtaa
    20341 gtccacgcta atgaacatgt tagcagggct tcttgaacca actagtggtg aaatcgcggt
    20401 caacggtcaa gttgtcaatc tcgactcccc atctaaagca gctagcttgg gaatcgggat
    20461 ggttcaccag cactttatgt tggttgaagc cttcacagtg gctgaaaaca tcattttagg
    20521 tagtgaattg actaaaaatg gtgtgctaga tatcgctgga gctagcaaag aaatcaaggc
    20581 tctttctgaa cgttatggct tagctgttga cccttctgcc aaggtagcag atatctcagt
    20641 tggagcccaa caacgtgtag aaattttaaa aacactttat cggggggctg atatccttat
    20701 ctttgacgaa ccaacggctg ttttgactcc atcagaaatt gatgagttga tggctattat
    20761 gaaaaatctt gtcaaagaag gaaaatcaat tatcttgatt acccacaaat tggatgaaat
    20821 tcgcgcagtt tctgaccgtg ttacagttat ccgtcgtggg aaatcaattg aaaccgttga
    20881 aattgcaggg gctaccaatg ctgatttggc ggaaatgatg gtagggcgtt ctgtttcctt
    20941 taaaacagag aagcaagcct ctaaaccaaa agaagtggtt ttgtctatca aagatttggt
    21001 ggtcaatgaa aaccgtggtg ttccagctgt taaaaatctg tccttggatg ttcgtgctgg
    21061 agagattgtt ggtattgcgg ggattgatgg aaatggtcag tctgaactga ttcaagccat
    21121 tacaggtctt cgtaaggttg aatctggtag cattgagcta aaaggagatt caattgtagg
    21181 cttgcaccca cgtcagatta cagaactaag tgttgggcac gttccagaag accgtcaccg
    21241 tgatggcttg attttggaaa tgatgatatc tgaaaatatt gcccttcaaa cctactataa
    21301 agaaccacat agtaaaaatg gaattttgaa ttattcaaat attacttctt atgctaaaaa
    21361 gctgatggaa gagtttgatg ttcgcgctgc cagtgaatta gttcctgcag ctgcactctc
    21421 aggaggaaat caacaaaaag caattattgc tcgtgaaatt gatcgagatc ctgatctcct
    21481 tatcgttagc cagccaactc gtgggttgga tgtcggtgcc attgagtata tccacaaacg
    21541 cttgattgaa gagcgtgata atggcaaggc tgtccttgtt gtcagctttg aattggatga
    21601 gattttaaac gtctcagacc gtattgccgt tatccacgat ggtaagattc aaggtattgt
    21661 atcaccagaa acaaccaata aacaagaact tggtgtcttg atggctggtg gaaacttggg
    21721 aaaggagaag agtgatgtct aaaaaattac aacaaatttc ggttcccttg atttctgtat
    21781 ttctaggaat tttactcgga gccattgtca tgtggatctt cggttatgat gctatttggg
    21841 gctacgaaga attgttctat acagcctttg gcagtctgcg tgggattgga gaaatcttcc
    21901 gtgctatggg tcctctggtc ttgattggtc ttggttttgc ggttgccagt cgagctggtt
    21961 tctttaacgt cggacttcct ggtcaggctt tggcaggttg gattctcagt ggttggtttg
    22021 cgctgtcgca tccagatatg ccccgtccct tgatgattct agcaaccatc gtgattgcct
    22081 tgattgctgg tgggattgtc ggagcgattc caggtattct tagggcctat ctagggacgt
    22141 cagaggttat tgtaaccatc atgatgaact acattgtctt gtatgtaggg aatgccttta
    22201 tccatgcttt ccctaaagac ttcatgcaaa gtacagattc gaccattcgt gttggggcta
    22261 atgcaactta tcagacacct tggttggctg agttgactgg taactcacgg atgaatattg
    22321 gtattttctt tgccatcatt gccgttgcag ttatttggtt catgctcaag aaaacaactc
    22381 ttggttttga aatccgtgca gttggtctta atccacatgc ttcagaatat gctggtattt
    22441 ctgccaagcg gactattatc ctatctatga ttatttcagg tgccttggca ggtcttggtg
    22501 gagctgttga aggtttggga accttccaga acgtctatgt tcaaggttcg tcattagcta
    22561 tcggatttaa cggaatggcg gttagtttgc ttgcggccaa ctcaccaatt ggtatactct
    22621 ttgcagcctt cctatttggc gttctccaag ttggggctcc tggtatgaat gcggcgcagg
    22681 taccatctga gcttgtcagc attgtaacag cgtctattat cttctttgtc agtgttcatt
    22741 accttatcga acgctttgtc aaaccgaaaa aacaagttaa aggaggtaag taaagatgtc
    22801 tattataacc ttgctccccc tcttggtgtc ttctatgctg atttactcag cacctctcat
    22861 ctttacaagt atcggtggtg ttttctctga acgtggtggt gtggtaaacg ttggccttga
    22921 aggaattatg gttatgggtg ccttttctgg agttgtcttt aaccttgaat ttgcagaaca
    22981 atttggagca gcaactccat ggctatcctt gcttgtagca ggattggttg gtagtgtttt
    23041 ctctatcatc cacgcagcag cgacggttca tttccgtgca gaccatgttg tcagcggtac
    23101 ggtattgaac ttgatggcgc ctgccttggc tgttttctta gttaaagttc tttataacaa
    23161 aggacaaacc gacaacctaa gtcaaacttt tggacgcttt gatttcccag tcttggcaaa
    23221 tatcccagtg attggtgata tcttcttcaa gtcaactagt ctacttggtt atctggcgat
    23281 tgccttctca ttccttgctt ggtttattct ctttaagact caatttggtc ttcgtctccg
    23341 ctctgtcggt gaacatcctc aagcagcgga taccttggga atcaacgtct acaagatgag
    23401 atatttaggg attattattt caggttttct aggtggaatt ggcggagcga tttatgcgca
    23461 atcaatctca gttaacttct cagtgacaac tattgttgga cctggattta tcgcccttgc
    23521 tgcgatgatc tttgggaaat ggaatccaat cggtgctatg ctttctagtc tcttctttgg
    23581 actttcacaa agtttggctg ttatcggttc tcaattgccg ttcctacaag gagtgccagc
    23641 ggtttatctt caaattgcac cttatgtttt gacaattctt gtcttagcag ccttctttgg
    23701 aaaagcagtc gcaccaaaag cagatggtat caactacatc aaatcaaaat aagcatacaa
    23761 aaaaacgtca gtccaatgac tgaactgccc cccaaaagtt agacagaaaa aatctaactt
    23821 ttggggtgtt tttattatga aactaactta tgatgataaa gttcagatct atgaacttag
    23881 aaaacaagga tatagcttag agaagctttc aaataaattt gggataaaca attctaatct
    23941 taggtacatg attaaattga ttgatcgtta cggaatagag ttcgtcaaaa aaggaaaaaa
    24001 tcgttactat tctcctgatt taaaacaaga aatgattcat aaagtctgac atgaaggcta
    24061 gactaaagat agagtttctc ttgaatacgg tctcccaagt cgtacgatac ttcttaactg
    24121 gctagcacaa tacaggaaaa acgggtatac tattgttgag aaaccaagag ggagagtacc
    24181 taaaatggga cgtaagccaa gaacgagacc tgaagagagg acagaattag aacgtcttca
    24241 agcagaaaat gagtacctga gagcggagaa tgccatccta aaaaagttaa gagaactccg
    24301 attgaaggag gaaaaagaga aagaagaaag atagaaattg ttcaagaatt aatgactgag
    24361 ttttcgttag atcttcttct aaaagccatt aaactagctc gttggaccta ctactatcac
    24421 ttgaaacagt tagacaaacc agataaggac caagagctta aagctgaaat tcaattcatt
    24481 tttatcgaac acaagggaaa ttatacttat cgccgggtt
//
LOCUS       DAVBOG010000032        22288 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.032, whole genome shotgun sequence.
ACCESSION   DAVBOG010000032 DAVBOG010000000
VERSION     DAVBOG010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22288
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.032"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(287..574)
                     /locus_tag="VQ865_001395"
     CDS             complement(287..574)
                     /locus_tag="VQ865_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000777751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135723.1"
                     /translation="MKLSNLLLFAGAAAGSYLVTKNRQTITDEVLNTTDRVQAIKDDV
                     DIIQNSLQIINQQKELIKEYQEDLTYKFKVLEKDIQTRLAVIKEMQGTEDK"
     gene            complement(584..994)
                     /locus_tag="VQ865_001396"
     CDS             complement(584..994)
                     /locus_tag="VQ865_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006150090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HET3135724.1"
                     /translation="MSDCIFCKIIAGEIPASKVYEDEQVLAFLDISQVTLGHTLVVPK
                     EHYRNLLEMDATSASQLFAQVPKVAQKVMKVTKAAGMNIISNCEEVAGQTVFHTHVHL
                     VPRYSADDDLKIDFIAHEPDFDKLAQVAETIKNA"
     gene            1062..1793
                     /locus_tag="VQ865_001397"
     CDS             1062..1793
                     /locus_tag="VQ865_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000889926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135725.1"
                     /translation="MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTI
                     NEIIGLLAPYSGSININGLTLQGDATSYRKQIGYIPETPSLYEELTLREHIETVAMAY
                     GIEQKVAFERVEPLLKMFRLEQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
                     LGLDPLAISDLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQ
                     LREAFDMPEASLNDIYLALTKEEDL"
     gene            1790..2839
                     /locus_tag="VQ865_001398"
     CDS             1790..2839
                     /locus_tag="VQ865_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135726.1"
                     /translation="MKDLFLKRKQAFRKECLGYLRYVLNDHFVLFLLVLLGFLAYQYS
                     QLLQHFPENHWPILLFVGITSVLLLLWGGIATYMEAPDKLFLLVGEEEIKLHLKRQTG
                     ISLVFWLFVQTLFLLLFAPLFLAMGYGLPVFLLYVLLLGVGKYFHFRQKASKFFTETG
                     LDWDYLISQESKRKQVLLRFFALFTQVKGISNSVKRRAYLDFILKAVQKVPGKIWQNL
                     YLRSYLRNGDLFALSLRLLLLSVLAQVFIEQAWIATAVVVLFNYLLLFQLLALYHAFD
                     YQYLTQLFPMDKGQKEKGLQEVVRGLTSFVLLVEVVVGLITFQEKLALLALLGAGLVL
                     LVLYLPYQVKRQMQD"
     gene            complement(3007..3336)
                     /locus_tag="VQ865_001399"
     CDS             complement(3007..3336)
                     /locus_tag="VQ865_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase BlpT"
                     /protein_id="HET3135727.1"
                     /translation="MTDTDPIKRAQTLITDLNKAYQACKQATADDVRFQEQLNSILGF
                     LAKAETVDNRFLIELEKFYQTSSLLMGLSALDPDAPTRAAWRAYDRFHFDQVKTKLIL
                     NENQRAN"
     gene            3613..3951
                     /locus_tag="VQ865_001400"
     CDS             3613..3951
                     /locus_tag="VQ865_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000682119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135728.1"
                     /translation="MKHMIIQTQKTVYKVNVDDVYYIQTHPTKAHTVKIVTEEASFNM
                     VQNLSNLENQYGETLMRCHRNCLVNLDKVKSIDFQERILFLGEEGQYAVKYARRRYRE
                     IRQKWLKEGE"
     gene            3956..4693
                     /locus_tag="VQ865_001401"
     CDS             3956..4693
                     /locus_tag="VQ865_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001219153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135729.1"
                     /translation="MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLL
                     AEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRDPYALIVFVTTHSEFMPLSFRYQ
                     VSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
                     LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKL
                     LFFPNGGSCLIARYKVREVSEAINNLH"
     gene            4707..6047
                     /locus_tag="VQ865_001402"
     CDS             4707..6047
                     /locus_tag="VQ865_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3135730.1"
                     /translation="MNVAWILLYTLVTHGLKIVIFFKVDGISLTFERIFKAFLFKILL
                     AVVFGMLGYMVGNVYLSYFMEPLYGIGLSFLLLRELPKKLLLFYGLFPMILVNLFYRG
                     VSYFVLPFLGQGQVYDDYSFIWLCIIIFNFFISLAFLKWLDYDFTSLRKGILDKDFQK
                     SLTQINWIMGAYYLVIQNLSYFEYEQGIQSTTVRHLILVFYLLFFMGIIKKLDTYLKD
                     KLHERLNQEQDLRYREMERYSRHIEELYKEVRSFRHDYTNLLTSLRLGIEEEDMEQIK
                     EIYDSVLKDSSEKLQDNKYDLGRLVNVRDRALKSLLAGKFIKARDKNIVFNVEVPEEI
                     QVEGVSLLDFLTVVSILCDNAIEASVEACQPHVSIAFFKNGAQETFIIENSIKEEGID
                     ISEIFSFGASSKGEERGVGLYTVMKIVESHPNTSLNTTCQDHVFRQVLTVIHIE"
     gene            complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ865_001403"
     CDS             complement(6091..6246)
                     /gene="blpC"
                     /locus_tag="VQ865_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system pheromone BlpC"
                     /protein_id="HET3135731.1"
                     /translation="MDKKQNLTSFQELTTTELNQIIGGGWWEDFLYRFNIIEQKNTKG
                     FYQPIQL"
     gene            complement(6303..7664)
                     /locus_tag="VQ865_001404"
     CDS             complement(6303..7664)
                     /locus_tag="VQ865_001404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin secretion accessory protein"
                     /protein_id="HET3135732.1"
                     /translation="MNPNLFRSVEFYQRRYHNYATVFIIPLSLLFTFILIFSLVATKE
                     ITVTSQGEIAPTSVIASIQSTSDNPILANHLVANQVVEKGDLLIKYSETMEESQKTAL
                     ATQLQRLEKQKEGLGILKQSLEKATDLFSSEDEFGYHNTFMNFTKQSHDIELGISKTN
                     TEVSNQANLTNSSSSAIEQEITKVQQQIGEYQELRDAIINNRARLPTGNPHQSILNRY
                     LIASQGQTQGTAEEPFLSQINQSIASLESSIASIKIQQAGIGSVATYDNSLATKIEVL
                     RTQFLQTASQQQLTVENQLTELKVQLDQATQRLENNTLTAPSKGIVHLNSEFEGKNRI
                     PTGTEIAQIFPVITDTREVLITYYVSSDYLPLLDKGQTVRLKLEKIGNHGTTIIGQLQ
                     SIDQTPTRTEQGNLFKLTALAKLSNEDSKLIQYGLQGRVTSVTTKKTYFDYFKDKILT
                     HSD"
     gene            complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ865_001405"
     CDS             complement(7675..9828)
                     /gene="blpA"
                     /locus_tag="VQ865_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_125458604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide cleavage/export ABC transporter BlpA"
                     /protein_id="HET3135733.1"
                     /translation="MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKT
                     NKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDVPYPFIVHVNKEGKLQHYYVVYQ
                     TKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLAPKPSYQPHKDKKNGLLSFLPL
                     IFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYIL
                     QQVMSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSII
                     DALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNH
                     DVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQT
                     SLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQS
                     AKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIK
                     QGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINYQDIKNIDKKVLRRHINYLPQQ
                     AYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGG
                     QKQRIALARALLTKAPVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAE
                     RTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK"
     gene            10110..10364
                     /gene="blpM"
                     /locus_tag="VQ865_001406"
     CDS             10110..10364
                     /gene="blpM"
                     /locus_tag="VQ865_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpM"
                     /protein_id="HET3135734.1"
                     /translation="MNTKMMEQFHEMDIAMLSSIEGGKNNWQTNVFEGGSAAFGGWGL
                     GTAICAASGVGAPFMGACGYIGAKFGVALWAGVTGATGGF"
     gene            10380..10583
                     /gene="blpN"
                     /locus_tag="VQ865_001407"
     CDS             10380..10583
                     /gene="blpN"
                     /locus_tag="VQ865_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001099492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-peptide bacteriocin subunit BlpN"
                     /protein_id="HET3135735.1"
                     /translation="MNTYCNINETMLSEVYGGNSGGAAVVAALGCAAGGVKYGKILGP
                     WGAAIGGIGGAVVCGYLAYTATS"
     gene            10827..10976
                     /gene="blpO"
                     /locus_tag="VQ865_001408"
     CDS             10827..10976
                     /gene="blpO"
                     /locus_tag="VQ865_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-like peptide BlpO"
                     /protein_id="HET3135736.1"
                     /translation="MNTKMMSQFSVMDNEMLACVEGGDIDWGRKISCAAGVAYGAIDG
                     CATTV"
     gene            11080..11199
                     /locus_tag="VQ865_001409"
     CDS             11080..11199
                     /locus_tag="VQ865_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000346296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin"
                     /protein_id="HET3135737.1"
                     /translation="MDFKSFIIGLVVGIFGPYMDDLIRKIFSKSSKKDTDSTL"
     gene            11667..12038
                     /locus_tag="VQ865_001410"
     CDS             11667..12038
                     /locus_tag="VQ865_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135738.1"
                     /translation="MIKKNHILCEIVPGSVAFACFYLSISISSVFQFLLVVINLASIL
                     VTVYLTREMRIKEFEDDDLVSPRTNQLMFIGLTGFMSIICLYRGITAGESYQQIIAYI
                     GAILCLTIMLLLIWGLKYYKK"
     gene            12667..13050
                     /locus_tag="VQ865_001411"
     CDS             12667..13050
                     /locus_tag="VQ865_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="immunity protein"
                     /protein_id="HET3135739.1"
                     /translation="MKYRLFFVIFLSSVLDILLGTFLQISIVSIGWLVLYSGLFEAGV
                     FLLANKGVAVKIKEVDIRNRFKFIFGKTLWFQILLLIFLIIKLYLGLDARLILFYGHI
                     FIVFNALMYLLSSSQVSLKKNKLSS"
     gene            13102..13791
                     /locus_tag="VQ865_001412"
     CDS             13102..13791
                     /locus_tag="VQ865_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000760553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135740.1"
                     /translation="MKKYQLLFKISAVFSYLFFVFGLSQMTLIIQNYWQFSSQIGNFV
                     WIQNFLSLLFSGVMIWILVKTGHGYLFHIPRKKWLWYSILTVLVVVLQISFNVQTAKH
                     VQSTAEGWAVLIGYSGTNFAELGIYITLFFLTPLMEELIYRGLLQHAFFKHSRFGLDL
                     LLPSILFALPHFSSLPSLLDIFIFATSGIIFASLTRYTKSIYPSYAVHVINNIFATLP
                     FLLTFLHRVLG"
     gene            13833..14066
                     /locus_tag="VQ865_001413"
     CDS             13833..14066
                     /locus_tag="VQ865_001413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135741.1"
                     /translation="MYKHLFFLDSKTLDRLTPYILVLASDTIAFNVFVLTFVSAVVFN
                     FLNSMLALMAIFIGAGYVVGFWLLILNENQRAN"
     gene            14217..14828
                     /locus_tag="VQ865_001414"
     CDS             14217..14828
                     /locus_tag="VQ865_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000394041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135742.1"
                     /translation="MEFFDKFHALCFGFLVLIIVITVPYTINHGVFFQNESALILVSL
                     LVTSLSVAYARKFEMISFGMLSKKQLLLFIAIFLLSVLETLVYIHFFAVSSGSGVQHL
                     AEVSRGISLSLILTTSVFGPIQEELIFRGLLQGAVFDNSWLGLVLTSSLFSFMHGPSN
                     VPSFIFYLLGGLLLGFAYKKSQNLWVSTLVHMFYNSWPLLYYL"
     gene            14989..15783
                     /locus_tag="VQ865_001415"
     CDS             14989..15783
                     /locus_tag="VQ865_001415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000363010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HET3135743.1"
                     /translation="MDLGDNELTLTPIPGKSGKAYMGSYPDGKRIFVKMNTSPILPGL
                     AREQIAPQLLWSRRLADGRDMCAQEWLTGKILTPYDMNRKQIVNILTRLHRSRPLMTQ
                     LSRLGYAMETPVDLLQSWQETAPDALRKNHFISEVMADLRQTIPGFREDHATIVHGDV
                     RHSNWIETDSGLIYLVDWDSVRLTDRMFDVAHMLCHYISEHQWKEWLTYYGYKYNQTV
                     LSKLYWYGQLSYLSQISKYYMNQDLENVNREIHGLRHFRDKYGKRR"
     gene            15780..16415
                     /gene="trmB"
                     /locus_tag="VQ865_001416"
     CDS             15780..16415
                     /gene="trmB"
                     /locus_tag="VQ865_001416"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001266107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HET3135744.1"
                     /translation="MRVRNRKGATELLEANPQYVVLNPLEAKAKWRDLFGNDNPIHVE
                     VGSGKGAFVSGMAKQNPDINYIGIDIQKSVLSYALDKVLEVGVPNIKLLWVDGSDLTD
                     YFEDGEIDRLYLNFSDPWPKKRHEKRRLTYKTFLDTFKRILPENGEIHFKTDNRGLFE
                     YSLVSFSQYGMKLNGVWLDLHASDFEGNVMTEYEQKFSNKGQVIYRVEAEF"
     gene            16541..17020
                     /gene="rimP"
                     /locus_tag="VQ865_001417"
     CDS             16541..17020
                     /gene="rimP"
                     /locus_tag="VQ865_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HET3135745.1"
                     /translation="MDAIATIVELVREVVEPVIEAPFELVDIEYGKIGSDMILSIFVD
                     KPEGITLNDTADLTEMISPVLDTIKPDPFPEQYFLEITSPGLERPLKTKDAVAGAVGK
                     YIHVGLYQAIDKQKVFEGTLLAFEEDELTMEYMDKTRKKTVQIPYSLVSKARLAVKL"
     gene            17064..18200
                     /gene="nusA"
                     /locus_tag="VQ865_001418"
     CDS             17064..18200
                     /gene="nusA"
                     /locus_tag="VQ865_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HET3135746.1"
                     /translation="MSKEMLEAFRILEEDKGIKKEDIIDAVVESLRSAYRRRYGQSDS
                     VAIDFNEKTGDFTVYTVREVVDEVFDSRLEISLKDALAINSAYELGDKIKFEEAPAEF
                     GRVAAQSAKQTIMEKMRKQTRAITYNTYKEHEQEIMSGTVERFDNRFIYVNLGSIEAQ
                     LSKQDQIPGEVFASHDRIEVYVYKVEDNPRGVNVFVSRSHPEMIKRLMEQEIPEVYDG
                     TVEIMSVAREAGDRTKVAVRSHNPNVDAIGTIVGRGGANIKKITSKFHPARYDAKNDR
                     MVPIEENIDVIEWVADPAEFIYNAIAPAEVDQVIFDENDSKRALVVVPDNKLSLAIGR
                     RGQNVRLAAHLTGYRIDIKSASEFEAMEDAASVELEVENDTVEE"
     gene            18222..18515
                     /locus_tag="VQ865_001419"
     CDS             18222..18515
                     /locus_tag="VQ865_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000857559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HET3135747.1"
                     /translation="MKTRKIPLRKSVVSNEVIDKRDLLRIVKNKEGQVFIDPTGKANG
                     RGAYIKLDNAEALEAKKKKVFNRSFSMEVEESFYDELIAYVDHKVKRRELGLE"
     gene            18508..18807
                     /locus_tag="VQ865_001420"
     CDS             18508..18807
                     /locus_tag="VQ865_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HET3135748.1"
                     /translation="MNKQKISNLLGLAQRAGRIISGEELVVKAIQDGKAKLVFLAHDA
                     GPNLTKKIQDKSHYYQVEIVTVFSTLELSIAVGKSRKVLAVTDAGFTKKMRSLME"
     gene            18824..21616
                     /gene="infB"
                     /locus_tag="VQ865_001421"
     CDS             18824..21616
                     /gene="infB"
                     /locus_tag="VQ865_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001863140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HET3135749.1"
                     /translation="MSKKRLYEIAKELGKESKEVVARAKELGLDVKSHSSSVEEAVAA
                     KIAASFKPAAAPKVEAKPAAPKVSAEKKAEKSEPAKPAVAKEEAKPAEPVAPKTEKVA
                     AKPQSRNFKAEREARAKEQAERRKQNKGNNRDQQQNGNRQKNDGRNGGKQGQSNRDNR
                     RFNDQAKKQQGQQKRRNERRQQEDKRSNQVAPRIDFKARAAALKAEQNAEYARSSEER
                     FKQYQAAKEALAQANKRKEPEEIFEEAAKLAEQAQQVQAVVEVVPEKKEPAVDTRRKK
                     QARPDKNRDDYDHEEDGPRKQQKNRSSQNQVRNQKNSNWNNNKKNKKGNNKNNRNQTP
                     KPVTERKFHELPTEFEYTDGMTVAEIAKRIKREPAEIVKKLFMMGVMATQNQSLDGET
                     IELLMVDYGIEAKQKVEVDNADIERFFVEDGYLNEDELVERPPVVTIMGHVDHGKTTL
                     LDTLRNSRVATGEAGGITQHIGAYQIVENGKKITFLDTPGHAAFTSMRARGASVTDIT
                     ILVVAADDGVMPQTIEAINHSKAANVPIIVAINKIDKPGANPERVIGELAEHGVMSTA
                     WGGDSEFVEISAKFNQNIEELLETVLLVAEIQELKADPTVRAIGTVIEARLDKGKGAV
                     ATLLVQQGTLNVQDPIVVGNTFGRVRAMTNDLGRRVKVAGPSTPVSITGLNEAPMAGD
                     HFAVYEDEKSARAAGEERAKRALMKQRQATQRVSLENLFDTLKAGELKSVNVIIKADV
                     QGSVEALSASLQKIDVEGVKVTIVHSAVGAINESDVTLAEASNAFIVGFNVRPTPQAR
                     QQAEADDVEIRLHSIIYKVIEEMEEAMKGMLDPEFEEKVIGEAVIRETFKVSKVGTIG
                     GFMVINGKVARDSKVRVIRDGVVIYDGELASLKHYKDDVKEVTNGREGGLMIDCYNDI
                     KMDDVIEAYVMEEIKR"
     gene            21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ865_001422"
     CDS             21867..22217
                     /gene="rbfA"
                     /locus_tag="VQ865_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001273594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HET3135750.1"
                     /translation="MANHFRTDRVGMEIKREVNEILQKKVRDPRVQGVTITDVQMLGD
                     LSVAKVYYTILSNLASDNQKAQIGLEKATGTIKRELGRNLKLYKIPDLTFVKDESIEY
                     GNKIDEMLRNLDKN"
BASE COUNT         6578 a         3871 c         4884 g         6955 t
ORIGIN      
        1 tgttttgagc tgacttcgtc agttctatcc acaaccttaa aacggtgttt tgagcagtct
       61 gtgcctagct ttctagtttg ctttttgatt tttattgagt atgagttacc taaattatga
      121 tgcatagttg atgggatata tataatagat tgaaatagaa tatgaacaaa ttgataagag
      181 gattttaaag taatctctaa caatgcttta gaaactatag tgtgctattc taaattcaat
      241 tcactataac ttgtttacgt tttaaaaaag agccgggggg ctctttttac ttatcttcag
      301 ttccctgcat ttcttttatc acagctagtc tagtctggat atccttttcc aagaccttaa
      361 acttgtaagt caagtcttct tggtattcct tgataagttc tttttgctgg ttaatgattt
      421 gcaggctgtt ttggataata tccacatcgt ccttgatagc ttgaacgcgg tcagtggtat
      481 tcaagacttc atctgtgatg gtttggcgat tttttgtaac cagataactt ccggctgcag
      541 ctcctgcaaa tagcagtagg ttggataatt tcatagcaac tccttaagcg tttttgatgg
      601 tttcagcgac ttgagcaagt ttgtcaaagt ctggttcgtg ggcgataaaa tcaatcttga
      661 ggtcatcgtc agcactgtag cgaggcacaa ggtgaacgtg agtatgaaaa actgtttgac
      721 cagcgacttc ttcacagttg gaaatgatat tcataccagc agccttagtg actttcatga
      781 ctttttgagc tacttttggt acttgggcaa agagttggct ggcgctcgta gcatccatct
      841 ccaaaagatt gcgatagtgt tcttttggca cgaccaaggt gtgtcctagt gttacttgag
      901 agatatcaag aaaggcaagg acctgctcat cttcatatac ttttgaagca ggaatttccc
      961 ctgcgatgat tttacaaaaa atgcaatctg acataaaatc tacctctact gtactgaatt
     1021 ttgatataat atagctacat tataccagat ttggagaaaa tatgttagaa attaaaaacc
     1081 tgacaggtgg ctatgttcat gttcctgttt tgaaagatgt gtcctttact gttgaaagtg
     1141 ggcagttggt cggtttgatt ggtctcaatg gtgctgggaa atcaacgacg atcaatgaga
     1201 ttatcggtct gttggcacct tatagtggct ccatcaatat caatggcctg actctgcaag
     1261 gagatgcgac tagctaccgc aagcagattg gctacattcc tgagacgcct agtctgtatg
     1321 aggaattgac cctcagagag catatcgaaa cggttgctat ggcttacggt attgagcaaa
     1381 aagtggcttt cgaacgagta gagcccttgt taaaaatgtt ccgtttggaa cagaaattag
     1441 actggttccc tgttcatttt tcaaaaggga tgaagcagaa ggtcatgatt atctgtgctt
     1501 ttgtggtgga tccaagtctt ttcatcgtgg atgagccttt ccttggtctt gatccgctgg
     1561 ctatttctga tttgattcag cttttggaag tggagaagca aaagggcaag tctattctca
     1621 tgagtaccca cgtgctggat tcggcggaga agatgtgtga tgcctttgtc attcttcaca
     1681 agggagaggt gcgtgccaaa ggcaatctcc tgcaactacg tgaagccttt gatatgcctg
     1741 aggctagttt gaatgatatt tacttggctc tgaccaaaga ggaggatcta tgaaagactt
     1801 gtttttaaag agaaagcagg cctttcgtaa ggagtgtctt ggttatctgc gctatgtgct
     1861 caatgaccac tttgtcttgt tcctgcttgt cctgttgggc tttctagcct accagtacag
     1921 tcaactctta caacattttc ctgaaaatca ttggcctatc cttttgtttg taggaattac
     1981 gtctgtttta cttttacttt ggggaggaat tgccacctat atggaggctc cagacaagct
     2041 ctttctctta gttggagaag aggaaatcaa gctccatctc aagcgtcaaa ctggcatttc
     2101 cctagtcttt tggctctttg tacagaccct tttcttgctg ttatttgcgc ccttgttttt
     2161 agcaatgggt tatggcttgc cagtttttct gctctatgtg cttttattgg gggtaggaaa
     2221 atatttccac tttcgtcaaa aggccagcaa atttttcact gaaactggac tggactggga
     2281 ctatcttatt tctcaagaaa gcaagcgtaa gcaagtcttg cttcgtttct ttgccctctt
     2341 tacgcaggtc aagggaattt caaacagtgt caagcgtcgt gcctatctgg actttatctt
     2401 aaaggctgtt cagaaggtgc ctgggaagat ttggcaaaat ctctatctgc gttcttatct
     2461 gcgaaatggc gacctctttg ctctcagtct tcgtcttctc ttactttccg tactggcgca
     2521 ggtttttatc gagcaagctt ggattgcgac agcagtggta gttctcttta actacctctt
     2581 gctcttccag ttgctggccc tctatcatgc ctttgactac cagtatttga cccaactctt
     2641 tccgatggac aaggggcaaa aggaaaaagg cttacaggag gtagttcgag gattgaccag
     2701 ttttgtttta cttgtggaag tagttgttgg gttgattacc ttccaagaaa aactagccct
     2761 tctagcctta ctaggagctg gtttggtttt actagtcttg tatttgcctt atcaggtaaa
     2821 acgtcagatg caggactaac attgctgata cgacactaaa aaagaagttg agttcagtct
     2881 gtctcaactt cttttttgtt actacaggat aatggttggt ccgtagagac ttatactctt
     2941 cgaaaatctc ttcaaaccac gtcagcgtcg tcttaccgta ctcaagtaca gcttgcggct
     3001 agcttcctag tttgctcttt gattctcatt gagtattaac ttggtcttga cttggtcaaa
     3061 gtggaagcgg tcataggccc gccaagcggc gcgagttgga gcatctggat caagagcgct
     3121 gagtcccatg agaagactgg aagtctggta aaatttttcc aattcaatca agaatcgatt
     3181 atccactgtt tcagccttgg ctagaaaacc aagaatagag tttaattgct cctgaaagcg
     3241 gacgtcgtca gcggttgcct gtttgcatgc ttgataggct ttgtttaagt cagtaatcaa
     3301 agtctgagct cttttgatag ggtctgtatc tgtcatgaga attcctcctc taatctgggt
     3361 gccagtcttg attctagcaa ctgtgttttg atactgtcag tctatcactt ttatctcctt
     3421 tttcgccttt aaatctttaa ttgtcattga aatgtcttga attgcgctga gtgaatttta
     3481 tgataaaata gtggtaagct catcatgata ttgtagaaaa ataattcttt taggagcttt
     3541 caaagactgt ttaggattgg gtgtgcttgt gttagatttt ttctgttatt cttttcttag
     3601 gaggagaatc caatgaaaca tatgattatt cagacacaga aaacagtcta taaagtaaac
     3661 gtcgacgatg tctactatat ccaaacacat ccaactaaag cccatactgt aaagattgtt
     3721 acagaagagg ctagttttaa tatggttcaa aatttaagta atcttgagaa ccaatatggg
     3781 gaaaccttga tgagatgtca tcgaaattgt ttggtcaatc ttgataaagt aaaatcgatt
     3841 gattttcaag aaagaatcct ttttcttgga gaagaaggtc aatacgctgt caagtatgcc
     3901 agacgtcgct atagagaaat tcgtcaaaaa tggttgaaag aaggagagta agaagatgag
     3961 aatatttgtt ttagaagatg atttttccca acagactaga attgaaacga cgattgagaa
     4021 actcttgaag gaacatcata tcactctgag ttcttttgaa gtttttggta agccagatca
     4081 attgctggca gaggtgcatg agaagggggc ccatcagcta ttctttttgg atattgagat
     4141 tcgaaatgag gagatgaagg gtctggaagt ggctagaaag attcgggatc gggatccgta
     4201 tgccctgatt gtctttgtga cgactcactc ggagtttatg cccctgtcct ttcgctacca
     4261 agtgtctgct ctggattata ttgataaggc cctttcggca gaggagtttg aatctcgtat
     4321 cgagacagcc ctcctctatg ccaatggtca agacagtaaa agtctagcgg aagattgctt
     4381 ttactttaaa tcaaaatttg ctcaattcca gtatcctttt aaagaggttt actatctcga
     4441 aacgtccaca agaccccatc gtgttattct ctataccaag acagacaggc tggaatttac
     4501 agcgagtcta gaggaggttc tcaagcagga gcctcgtctc ttgcagtgcc atcgctcttt
     4561 tctcatcaat cctgccaatg tggtgcattt agataagaaa gaaaaactgc ttttctttcc
     4621 caatggtgga agttgtctaa tcgcgcgtta taaggtcagg gaagtgtctg aggctattaa
     4681 taacttacac tgagctagga gagtttatga atgttgcttg gatattgttg tatacacttg
     4741 ttactcacgg attaaaaatt gtcatattct ttaaggtaga tggaattagt ctcacttttg
     4801 agaggatttt taaggccttt ctttttaaga tactgttggc cgttgttttt ggaatgcttg
     4861 gctatatggt aggaaatgtt tacctatctt attttatgga acccttgtac ggcataggct
     4921 tatctttctt attgttaaga gaacttccta aaaaactcct tctcttttat ggtctctttc
     4981 caatgatatt agtgaatctc ttttatagag gtgtttccta ttttgtgctt ccatttttgg
     5041 gacaagggca agtatatgat gactactcat ttatttggtt atgtataata attttcaatt
     5101 tcttcatttc tctagctttt ttgaaatggt tggactatga tttcactagc ttgagaaagg
     5161 ggattctcga taaagatttt caaaagtccc tgactcagat taactggata atgggggctt
     5221 actatttggt gatacaaaat ctgtcttact ttgaatatga acaggggatt caatcaacga
     5281 ctgttcgcca tctcatccta gtcttttacc tgctcttttt tatggggatt atcaagaaat
     5341 tggataccta tttgaaggac aaactccatg agagactgaa ccaagagcag gacttgcgct
     5401 acagagagat ggagcggtat agtcggcata tagaggagct ttataaggaa gtacggagtt
     5461 ttcgccatga ctacaccaac ctcttgacta gcttacgtct gggcattgaa gaggaggata
     5521 tggagcagat aaaagagatc tacgactcgg tcttaaagga ttctagtgaa aaattgcagg
     5581 acaataaata tgaccttggc cgattggtga atgttcggga tcgtgccctc aaaagtctcc
     5641 tagctggaaa atttataaaa gctagagata agaacattgt ctttaatgtc gaagttccag
     5701 aggagattca ggtagagggg gtgagtctac ttgattttct aaccgttgtg tctatccttt
     5761 gtgacaacgc tattgaagct agtgtagaag cctgtcaacc tcatgtttca attgcctttt
     5821 ttaaaaatgg agcacaggag acctttatca ttgaaaattc catcaaagaa gagggaatcg
     5881 atatttctga aatcttctcc tttggagcaa gttctaaagg ggaggagaga ggagttggtc
     5941 tctataccgt tatgaaaatt gtggaaagtc atcccaatac cagtctcaat accacctgcc
     6001 aagatcacgt ttttcgtcag gtacttactg taatacatat agaatgaaga aaaaataaga
     6061 ccgagagtgc gttctcttgg tcttgttttt ttatagttgt attggctgat aaaatccttt
     6121 tgtatttttt tgttcaatta tattaaatct atataagaaa tcttcccacc atcctccacc
     6181 tataatttgg ttgagttcgg tagttgttag ttcttgaaat gaagttaggt tttgtttctt
     6241 atccatgtta tgattctcct ttttgataag ataataaata gttatagagt gttatctgaa
     6301 aattaatcag aatgggttaa aattttatct ttgaaataat caaaatatgt tttctttgta
     6361 gttacactag tgacgcgacc ttgtaagcca tattggatga gtttactatc ctcgttagat
     6421 agttttgcaa gagcggttaa tttaaagaga ttgccttgct ctgttctggt aggagtttga
     6481 tcaatactct gaagttggcc gatgatggtg gtgccgtgat ttccaatctt ctccagtttt
     6541 aatcttacag tttgtccttt atctagtaag gggagatagt cagatgatac gtagtaagtg
     6601 attagtactt ctcttgtatc tgtgatgaca gggaatattt gagcaatttc tgtaccagtt
     6661 ggaattctat ttttaccttc aaattcgctg ttcagatgaa cgataccttt acttggagcg
     6721 gttaaggtat tattttctaa gcgctgtgtc gcttgatcta gttgtacttt taattctgtt
     6781 aattgattct ccacggttag ttgttgctgt gaggctgttt gtaaaaactg agtgcggagt
     6841 acttcaattt tggttgctaa actattatca taagttgcta cacttccgat accagcttgc
     6901 tgaattttga tgcttgcgat agatgattca agacttgcaa tactttgatt aatttgagat
     6961 aaaaatggct cctctgccgt tccttgtgtt tgtccttgag aggctataag ataacgattt
     7021 aaaattgact ggtgcggatt gccagttggt aagcgtgctc tgttatttat gatagcatct
     7081 ctcaactctt gatattctcc aatttgttgt tgaacttttg taatttcttg ttcgatggct
     7141 gatgaactgc tattggtaag attagcttga tttgaaactt cagtgttagt ctttgagata
     7201 cccagttcaa tatcatggga ttgtttagta aaattcataa aggtattatg gtagccaaac
     7261 tcatcctcgc tagaaaaaag atcagtcgct ttttctaagc tttgtttcaa gattccaagt
     7321 ccttcttttt gcttctcaag tctttgtaat tgagttgcta aggcagtttt ctgactttct
     7381 tccattgttt cagagtattt gatgagtaag tcacctttct caactacttg atttgccact
     7441 aaatgattag caaggatagg attatcactg gtcgactgaa tagatgcaat gacacttgta
     7501 ggggcgattt ctccttggga agtaacagta atttcttttg tggcaacaag ggagaaaatc
     7561 aagatgaaag taaatagtaa tgaaagaggt ataatgaaca ctgtcgcata gttatggtaa
     7621 cgtctctgat aaaactcgac acttctaaaa agattaggat tcatgacatt ctccttattt
     7681 attgaataga tgatggtaga agccttgcgc ctgcattaac tcttggtgac taccaacttc
     7741 aatgattttc ccctggtcaa gaacaatgac acggttagtt cgttcggcta tactgagacg
     7801 atgggctaca aagagaatgg ttttatcagt tagggatata agattatcta taaccttttt
     7861 ctcagtcaag acatcaagac cgctagtagc ttcatctagt attaaaacag gagctttagt
     7921 taaaagagca cgagcgagag cgattcgttg cttttgtcct cctgatagac cagctccatc
     7981 agagagctga gtttgatagc ccataggcat tctttcaatg tcttgacgga tttcagctaa
     8041 ttcacaagct cttagaatat cttcttggct aatcatatga ttaccgccca aggttaaatt
     8101 ttccaagata gagccattaa agatataggc ttgttggggt aggtaattaa tatgacggcg
     8161 caagactttt ttatcaatgt ttttaatatc ctgataattg atggaaatat gccctttgta
     8221 gggttcaaag aaattgacaa tcattttggc taaagttgtt ttaccagaac cactaactcc
     8281 aactaggcta accttatctc cttgtttaat cgtgagatta atatctgtta aggtatctcg
     8341 tccaaaacca tacttataag aaaggtcatc aaattcaata tcgcccatca aaaaatgtga
     8401 atgaacaggg ttttcttgaa cttgaaattc agattcgact agatagactt cgttcaaacg
     8461 gttattagcg accttcgcag attggagttt ggtttggagg ttgataatat tttccatagg
     8521 agttgtaaag taagaaaaaa gtgtgttaaa ggtaatcagc tgaccgatag aaattttact
     8581 cgacatgact aattgagcgc caaaccatag gataaggata ttcagaacta attttgttcc
     8641 ctgctttaaa ctcgtttgta aaatagaata tttactgagc ttaaaggatt tttccaaata
     8701 atctacaaat tcgctgtcta tattttgata gcgattttct tcactcgtga gcgactttat
     8761 agtttcaatc ccgttgatat cttcgataat ggcagagcta accatagaat tactttgcat
     8821 gacatcatgg ttcatttttt cgaaaggttt cataaaagaa aagatgatga acatgtatat
     8881 aggaatggaa agaagagaaa ggaggaagag attagggttt tgtgccagta agacgccccc
     8941 tacaagaatc agaatagaaa catccagaaa aagagaaaga atggtagaag ccaaggcatc
     9001 tataatagag ttagcatctg tgaaccgtga aatgatttct cctgtacgac gtgtcgcaaa
     9061 gaaagacatg ggaagttcaa aaatatggcg aatataggat aaaatcacat caatgcttaa
     9121 tctctggctc agaacggtta ggagataatc tctggaaaag ctcatgactt gttggaggat
     9181 ataggtgata accagaccaa ctgagatgat tcctaaagtt gatttcatct gatttgggat
     9241 gtattcatcc aagattcctt ggagataata agaaccaccg atattgataa tagtgaccaa
     9301 taagcttgag agaacaatgt aagcaatgag agatttttgt ttgaaaatca gaggaaggaa
     9361 gcttagtaga ccattctttt tatctttatg gggttgatag ctgggtttgg gagctagaaa
     9421 aatagctact ccagtccatt cagagaaaaa gcgttctttt gacattttag tgatttttac
     9481 agaagggtca ggatcaccaa taatcagata gtctttcttt gtttgataga caacatagta
     9541 atgttggagt tttccttctt tgttaacgtg aacgataaat ggatagggga catcactcat
     9601 gtcaaagaga gttttatctg cttgaacagg ccttgtttca aagcccattt catcagcggc
     9661 ttttacaatg ccaagagcag tcgtcccttc tttattggtc tttgcaagtt ctctcaagtg
     9721 agctagagaa aaatctgaac catagaattt agcaatcgag gctaaggcag caacaccgca
     9781 gtctctagca tctatttgag gaacaaatgt acgtttataa gaagtcattg gcaattcctt
     9841 tcatatagtg gatagctcta ttatgacata aaaacaattt cgtgctttat aaaatcttga
     9901 atagtcattg aaatttcctg aatggtaaaa aagtgattag aaattatctt ttaaaaaaaa
     9961 tttagaggta gttttaaata aaaaagctaa tttaagacgt ttcgatgaca attcaagatt
    10021 tggatgaaaa actttaacaa atagtgctat actaaacttg tcaaagttgc aacaagacaa
    10081 aaattaaaaa taaaaaagga gtatttgtta tgaatacaaa aatgatggaa caatttcatg
    10141 aaatggatat agctatgtta tctagtattg aaggaggcaa gaataattgg caaactaatg
    10201 ttttcgaagg tggtagtgct gcttttggtg gctgggggtt agggacagct atttgtgctg
    10261 cgagtggtgt tggagcgcca tttatgggag catgtggata cataggagct aaatttggtg
    10321 tggctctttg ggcaggagta acaggggcaa cgggtggatt ttaacaaaag gagacttgta
    10381 tgaatactta ttgtaatata aatgaaacaa tgctgagtga ggtttacgga ggtaattccg
    10441 gaggagcagc tgtagttgct gctttaggtt gtgcagcggg tggagtgaaa tatgggaaaa
    10501 ttctaggacc atggggcgct gcaataggag gaattggagg agcagtggtt tgtggatatt
    10561 tagcctatac cgctacatca taaaaatgaa agctaaattt tatgaaggct atattcttta
    10621 ttattctctt cgcttttcaa acctatctta tttatctatc cataagtatc tctgataaaa
    10681 aacaaaagac tattgaatta acatcattga attgttttgt catattattt ctaatctatg
    10741 ataaattaat ttttctcttt attgcctatg tttttttgat aatttttata ttaaacttgt
    10801 tccgtaactg aaaagtgaca tactatatga atacaaaaat gatgtcacaa ttttctgtta
    10861 tggataatga aatgcttgct tgcgttgaag gtggagatat tgattgggga agaaaaatta
    10921 gttgtgcagc aggggttgca tatggcgcaa ttgatgggtg tgcaacaacg gtttgacatt
    10981 tctattggga ccatttgcta taggaatagg tgtaactggt gctgcaggtg gagctatact
    11041 tggaggtgta gcctatgcag caacatgttg gtggtaatta tggattttaa aagttttatt
    11101 attggtttag tagttggtat atttggtcct tatatggatg acttaattag aaaaatattt
    11161 tcaaaatctt ccaaaaagga tacggatagt actctctaaa aaataaattt ctcccctgta
    11221 tttgctagct taatttacag gggagtttct ttaatattgt ttcgcctgtc aaaatgatat
    11281 gtgatagcag gatgaaaagt ctacaaacaa gttggtatca atacaatata aagaggaaag
    11341 tatgtttttc atgcttgctt ttttaatttt tacaattcaa gaggttttga tgaccattta
    11401 tgatttgagt gatccaaggt caaaataagt gctatactag cagtgtaaat gttcttgctc
    11461 aactaagata aatcgcacat ttaggaggaa atcttatgaa gaaaaaaata ctgattattt
    11521 tcgttctgta tctgatcatg tccatctttc tttatccgct tagggagagt atttggtata
    11581 atctatttta taccatagcc tatatgattg cggttatgat ctatttttct ttaattaaaa
    11641 agaaagaaaa gaaatgaaag attttcttga ttaaaaagaa tcatattctt tgtgagattg
    11701 ttcctgggtc agttgccttt gcttgtttct acttatctat ttctatttcg tcagttttcc
    11761 aatttctttt agtggttatt aacttagctt ctattttggt cactgtttac ctcactaggg
    11821 aaatgcggat aaaagagttt gaagatgatg atttggttag tcctagaacc aatcaactta
    11881 tgttcatcgg cttgacaggc tttatgtcta ttatttgttt gtatagaggg atcacagcag
    11941 gagaatccta ccaacaaata atcgcttata ttggcgctat tctctgcttg accatcatgc
    12001 ttctgctcat ttggggattg aagtattata aaaagtagag gctaatgcag tttttgcaat
    12061 ttaagatgtc ttgatgacaa ttcaagattt ggatgaaaaa ctttgacaaa tagtgctata
    12121 ctgaaattgt caaagttgca acgggtgctg ctacattatg ttaaaaatcg ctcttgattg
    12181 ataagttgga tttgttagga aaggagtaaa taattatgga taagaaaaag atagtttcga
    12241 ctataatatg tatagtattt cttgtagtgt cagtagataa tttttttaga gacttaaccc
    12301 cgttactgtt cattttaaat attattggcc tgtcttgctt ttcagtgcta acatacatta
    12361 acataaaaga gatactctta aatataagta aatgatgatt tggttagtcc tagaaccaat
    12421 caacttatgt ttatcggctt ggcagatttt atgtttgtca tttgtttgta tagaggtatt
    12481 tcagaaacag aattctatca acaactaatc gcttatatag gtgtattctc tgcttgttta
    12541 tcacgcttct gctcatgtgg ggcttgaagt attataaaaa gtagctttct atccttttct
    12601 gacaggatat ttgagtagaa ggctctatta aattgttagt gaaataaatg aatggaggta
    12661 tttaatatga aatacagatt attttttgtt attttcttga gtagtgtgtt ggatattctt
    12721 ttagggacat ttttacaaat ctctatcgta tctattgggt ggcttgttct ttacagtggt
    12781 ttgtttgaag caggagtttt ccttcttgct aataaagggg tggcggtaaa aatcaaggaa
    12841 gtagatattc gaaatcgctt taaatttatt tttggaaaaa ccttatggtt tcaaattctt
    12901 ttgctcatct ttttgataat caaactttat cttggtttgg atgcgaggtt gattttattc
    12961 tatggacata ttttcattgt ctttaatgcc ttaatgtatc tattatctag tagtcaggtt
    13021 agccttaaaa aaaacaaact gtcttcttaa tcttacagca gtagagcctg acaaggtgag
    13081 gtcatagtag ggaggatttc tatgaaaaag tatcaacttc tattcaaaat aagtgcagtt
    13141 ttctcttact tatttttcgt atttggtctt tctcagatga cgcttattat tcaaaattat
    13201 tggcaatttt cttcccagat tggcaatttc gtctggattc aaaatttctt gagtttgcta
    13261 tttagcggag tcatgatttg gattctggtt aagacaggtc atggttatct ctttcacatt
    13321 ccaagaaaaa aatggctttg gtattcgatt ttgacagtat tagtggtagt gctccagatc
    13381 tcttttaacg ttcagacagc taaacatgtt cagtcaactg ctgaaggttg ggctgtattg
    13441 atcggttata gtgggaccaa ctttgctgag ctaggtatct atataacttt gttctttctg
    13501 actccactta tggaagagct aatctataga ggattactgc aacacgcctt ttttaagcat
    13561 tcgagatttg gccttgattt gcttcttccg tcaattttat ttgctcttcc tcatttttca
    13621 agcctgccta gtttgttaga tatcttcatc tttgcaacat ctggcatcat ctttgctagt
    13681 ttgacccgct ataccaagag catttatcct tcctatgcgg tgcatgtgat caataatatt
    13741 ttcgcaacat taccattttt gctgactttt ttacataggg tcttggggta aaaaaacaaa
    13801 aggcttgctt ttcagccata gaggagatta tcatgtataa acacttattt ttcctagatt
    13861 ccaaaacttt agatcggttg acaccctata ttctagtctt ggcttctgac accattgctt
    13921 ttaatgtttt tgtgctaacc tttgtatctg cggtggtttt taatttccta aattccatgc
    13981 tagctttaat ggctatattc ataggggctg gctatgtggt cggattttgg ttactaatac
    14041 tcaatgaaaa tcaaagagca aactaggaaa ctagccgcag gctgtacttg agtacggcaa
    14101 ggcgacgttg acgtggtttg aatttgattt tcgaagagta taaaatggtt tgttttggaa
    14161 aggctagaac taaagaatga cgcgtaggaa gtctgtttgg tgaggaggat agttttatgg
    14221 agttttttga taaatttcat gccttgtgtt ttggattttt agtactaata attgtcatta
    14281 cagttcctta tacgattaac catggggttt tttttcaaaa tgaatctgca ttgattcttg
    14341 taagtcttct tgtaacctcg ctgagtgttg cttatgctag aaagtttgaa atgatttctt
    14401 ttgggatgtt aagcaagaaa caacttttgc ttttcattgc aatctttctt ctaagtgtac
    14461 ttgagacgct ggtttatatt catttcttcg ctgtttcttc tggctcaggg gtccaacact
    14521 tggcggaagt cagcagagga atttccctgt ctttgatttt gactacctca gtttttggcc
    14581 ccatccagga ggaactcatt ttcagaggac ttcttcaagg tgcggttttt gacaattctt
    14641 ggttagggct tgtgctaact tcctctctct tttctttcat gcatggacct tctaatgtcc
    14701 cttcgtttat tttttatcta cttgggggtt tgttgctggg ctttgcttat aaaaagagtc
    14761 aaaacctatg ggtttctact ctagtccaca tgttttacaa cagttggcca ctcctatatt
    14821 atttataaaa attatgaaaa ggtaagcaga agatggtgct tacctttttc aagctataat
    14881 gatacccaag ccaatccaga ggcttttctt tgagaatcgg gttagagtgg ttgacgaata
    14941 ggccaaaaac tagtagaata gtaaggaaac tttatacgga ggaaagaaat ggatttgggt
    15001 gataatgagc taacactgac tcccatacct gggaaaagtg gcaaggctta tatgggtagc
    15061 tatcctgacg ggaagcgcat ctttgtaaaa atgaacacct ctccaatcct acctggtcta
    15121 gctagagaac aaattgctcc acaattatta tggagtcgtc gtttggcaga tgggcgtgat
    15181 atgtgtgctc aagaatggtt gacaggcaag atattgaccc cctatgatat gaatcgtaag
    15241 caaatcgtca atattttaac ccgtcttcat cgctcacgtc cgttgatgac acaattgagt
    15301 cgtttgggct atgccatgga aacacctgta gatttactac agtcttggca ggaaacggct
    15361 ccagatgctt tgcgtaaaaa tcattttatc agtgaagtga tggctgattt acgtcagact
    15421 attccaggat ttagagagga ccatgcgacc attgtccatg gagatgtacg acatagtaat
    15481 tggattgaga cagatagtgg cttgatttat ttagtagatt gggattcggt tcgcttgacc
    15541 gatcgcatgt ttgatgtggc ccatatgctc tgccattata tttcagaaca tcagtggaag
    15601 gaatggttga cctactacgg ttacaagtac aatcaaacgg tattaagtaa attgtattgg
    15661 tatggtcaat tgtcttattt gagtcagatt tccaagtatt atatgaacca agatttagaa
    15721 aatgtcaatc gggagattca tggtttgcgt catttccgag acaagtatgg aaagagaaga
    15781 tgagagttag aaatcgtaaa ggggcaacag aattactaga ggcaaatccc cagtatgtgg
    15841 tcctcaatcc cttggaagcc aaggcaaaat ggcgggactt gtttggcaat gataatccca
    15901 ttcatgtgga agttggaagt ggaaagggtg cctttgtttc aggtatggcc aagcaaaacc
    15961 ctgacatcaa ctatatcggg attgatattc aaaagtctgt tttgagctac gctttggaca
    16021 aggtgcttga agttggagtg cctaacatca agctcttgtg ggtagatggt tctgacttaa
    16081 ctgactactt tgaagacggt gagattgatc gcttgtatct gaacttttca gatccatggc
    16141 cgaaaaaacg ccatgaaaag cgtcgtttga cctacaagac cttcttggat accttcaaac
    16201 gtatcttgcc tgaaaatgga gaaattcatt tcaagacgga taaccgtggc ttgtttgagt
    16261 acagtttagt gagcttttct caatatggca tgaaactcaa tggtgtctgg ttagatttgc
    16321 atgccagtga ttttgaaggc aatgtcatga cagaatacga gcaaaaattc tcaaacaagg
    16381 ggcaagttat ctaccgagtt gaggcagaat tttaagagat agcctaaaat taggctgtac
    16441 aagtgctttt gctttacata agttggcaaa cgtgctatac tgatagtaag aatatgaaaa
    16501 gtgaggcggg gaaatatctt cgcctcttgc ttatgaggag gtggacgcaa tcgcaacaat
    16561 cgtagaatta gtcagagaag ttgtagaacc tgtcatagaa gctccttttg aactcgtgga
    16621 tatcgagtat ggaaagattg gcagtgacat gattctcagt atttttgtag ataaacccga
    16681 aggaattacc ttgaacgaca cggcagactt gacagaaatg atcagtcctg tcctagacac
    16741 catcaagcca gatcccttcc cagaacaata tttcctagaa attaccagtc caggtttgga
    16801 acgtcctttg aaaaccaagg atgccgtcgc tggagcggtt ggaaaataca tccatgtcgg
    16861 gctctaccaa gccatcgata agcaaaaggt ctttgaagga accttgttgg ccttcgaaga
    16921 ggacgagttg actatggaat atatggacaa gacgcgtaag aaaaccgtcc aaattccata
    16981 cagtttagta tcaaaagcac gtttagcagt taaattatag aaaaagaaag gatagctttt
    17041 gaggattcaa aagtgaagaa aacatgagta aagaaatgct agaggccttc cgcattttgg
    17101 aagaagacaa gggaatcaaa aaagaagata tcatcgacgc agtagtagag tcgcttcgtt
    17161 ccgcttatcg cagacgctat ggtcagtcag acagcgtagc tattgacttc aacgaaaaaa
    17221 caggtgactt tacagtttat actgtccgtg aagttgttga tgaagtattt gatagccgtt
    17281 tggaaatcag cttgaaagat gctcttgcca ttaattcagc ttatgaactt ggagacaaaa
    17341 tcaagtttga agaagcacca gctgagtttg gtcgtgtagc agcccaatct gccaaacaaa
    17401 ccatcatgga aaaaatgcgc aagcaaacac gtgccatcac ttacaatact tacaaagaac
    17461 atgagcaaga aatcatgtct ggtacagtag aacgctttga caaccgcttt atctatgtca
    17521 accttggtag catcgaagcc caattgtcaa aacaagacca aattcctgga gaagtttttg
    17581 cttctcatga tcgtatcgaa gtttatgttt acaaggttga agacaaccct cgtggtgtga
    17641 acgtctttgt tagccgtagc catccagaaa tgatcaaacg tttgatggag caagaaattc
    17701 cagaagttta tgatggaact gttgaaatca tgagcgtggc tcgtgaagca ggtgaccgta
    17761 cgaaggttgc tgttcgtagc cacaatccaa acgtggatgc tatcggtaca atcgttggac
    17821 gtggtggtgc taatatcaag aagattacta gcaaattcca cccagctcgt tacgatgcta
    17881 aaaatgaccg catggtacca atcgaagaaa atatcgatgt tatcgagtgg gtagcagatc
    17941 cagctgaatt tatctacaat gccatcgctc ctgctgaggt tgaccaagtt atctttgatg
    18001 aaaacgacag caaacgtgcc ttggtggttg ttccagataa caagctttct cttgccattg
    18061 gtcgtcgtgg acaaaacgtg cgcttggcgg ctcacttgac tggttaccgt atcgatatca
    18121 agtctgctag cgaatttgaa gccatggaag acgctgcttc agtagagttg gaagtagaaa
    18181 acgatactgt agaagaataa aagctgctag aggagggaaa gatgaaaaca agaaaaatcc
    18241 ctttgcgcaa gtctgttgtg tctaacgaag tgattgataa gcgtgatttg ctccgcattg
    18301 tcaagaacaa ggaaggacaa gtctttattg atcctacggg caaggccaat ggccgcggcg
    18361 cttatatcaa actagacaat gcagaagccc tagaggcgaa aaagaagaag gtctttaacc
    18421 gcagttttag catggaagtg gaagaaagct tttatgacga gttgatcgct tatgtggatc
    18481 acaaagtgaa aagaagagag ttgggacttg aataagcaaa agataagtaa tctcttgggg
    18541 cttgctcagc gagcagggcg catcatatcg ggtgaagaat tggtggtcaa ggccattcaa
    18601 gacggcaagg ccaagttggt ctttctagct catgatgctg gacccaatct gaccaagaag
    18661 attcaagata aaagtcatta ttatcaagta gaaattgtaa ccgtgttttc aacactggaa
    18721 ttaagcatag cagtcgggaa atcgagaaag gttttggctg taacagatgc tggatttaca
    18781 aagaaaatga ggtctcttat ggaatagaag aggaggacat gatttgtcta agaaaagatt
    18841 gtacgaaatc gcaaaagaac ttggaaaaga aagtaaagaa gttgtagcgc gtgcaaaaga
    18901 gttgggcttg gatgtgaaaa gccactcatc aagtgtggaa gaagctgtcg ctgcaaaaat
    18961 tgctgccagc tttaagcctg cagctgctcc gaaagtagaa gcaaaacctg cagcaccaaa
    19021 agtaagtgca gaaaagaaag ccgaaaaatc tgagccagct aaaccagctg tagctaagga
    19081 agaggcaaaa ccggctgagc cagttgctcc gaaaacagaa aaagtagcag cgaaaccgca
    19141 aagccgtaat ttcaaggctg agcgtgaagc ccgtgctaaa gagcaggcag aacgacgcaa
    19201 gcaaaataag ggcaataacc gtgaccaaca acaaaacgga aaccgtcaga aaaacgacgg
    19261 ccgtaatggt ggaaaacaag gtcaaagcaa ccgcgacaat cgtcgcttta atgaccaagc
    19321 taagaagcag caaggtcagc aaaaacgtag aaatgagcgc cgtcagcaag aggacaaacg
    19381 ttcaaatcaa gtggctccac gtattgactt taaagcccgt gcagcagccc taaaagcaga
    19441 gcaaaatgca gagtacgctc gttcaagtga ggaacgcttc aagcagtatc aggctgctaa
    19501 agaagccttg gctcaagcta acaaacgcaa ggaaccagag gaaatctttg aagaagcggc
    19561 taagttagct gaacaagcac agcaagttca agcagtggtt gaagtcgtcc ctgagaaaaa
    19621 agaacctgca gtggatacac gtcgtaaaaa acaagctcga ccagacaaaa atcgtgacga
    19681 ttatgatcat gaagaagatg gtcctagaaa acaacaaaag aatcgaagta gtcaaaatca
    19741 agtgagaaat caaaagaata gtaactggaa taacaacaaa aagaacaaaa aaggcaataa
    19801 caagaacaac cgtaatcaga ctccaaaacc tgttacggag cgtaaattcc atgaattgcc
    19861 aacagaattt gaatatacag atggtatgac cgttgcggaa atcgcaaaac gtatcaaacg
    19921 tgaaccagct gaaatcgtta agaaactttt catgatgggt gtcatggcca cacaaaacca
    19981 atccttggat ggggaaacaa ttgaactcct catggtggat tacggtatcg aagccaaaca
    20041 aaaggttgaa gtggataatg ctgacatcga acgtttcttt gtcgaagatg gttatctcaa
    20101 tgaagatgaa ttggttgagc gtccaccagt tgttactatc atgggacacg ttgaccacgg
    20161 taaaacaacc cttttggata ctcttcgtaa ctcacgtgtt gcgacaggtg aagcaggtgg
    20221 tattactcag catatcggtg cctaccaaat cgtggaaaat ggtaagaaga ttaccttcct
    20281 tgatacacca ggacacgcgg cctttacatc aatgcgtgcg cgtggtgctt ctgttaccga
    20341 tattacgatc ttggtcgtag cggcagatga cggggttatg cctcagacta ttgaagccat
    20401 caaccactca aaagcagcta acgttccaat catcgtagcc attaacaaga ttgataaacc
    20461 aggtgctaac ccagaacgcg ttatcggtga attggcagag catggtgtga tgtcaaccgc
    20521 ttggggtgga gattctgaat ttgttgaaat ctcagctaaa ttcaaccaaa atatcgaaga
    20581 attgttggaa acagtccttc ttgtagctga aatccaagaa ctcaaggcag acccaacagt
    20641 gcgtgcaatc ggtacggtta tcgaagcgcg cttggataaa ggaaaaggtg cggtcgcaac
    20701 ccttcttgta caacaaggta ccttgaatgt tcaagaccca atcgttgtcg gaaatacctt
    20761 cggtcgtgtc cgtgctatga ccaacgacct tggtcgtcgt gttaaagttg ctggaccatc
    20821 aacaccagtc tctatcacag gtttgaacga agcaccgatg gcgggtgacc actttgccgt
    20881 ttacgaggat gaaaaatctg cgcgtgcagc aggtgaagag cgtgccaaac gtgccctcat
    20941 gaaacaacgt caagctaccc aacgtgttag ccttgaaaac ctctttgata cccttaaagc
    21001 tggggaactc aaatctgtta atgttatcat caaggctgat gtacaaggtt ctgttgaagc
    21061 cctttctgcc tcacttcaaa agattgacgt ggaaggtgtc aaagtgacta tcgtccactc
    21121 agcggtcggt gctatcaacg aatcagacgt gacccttgcc gaagcttcaa atgcctttat
    21181 cgttggtttc aacgtacgcc ctacaccaca agctcgtcaa caagcagaag ctgacgatgt
    21241 ggaaatccgt cttcacagca ttatctacaa ggttatcgaa gagatggaag aagctatgaa
    21301 agggatgctt gatccagaat ttgaagaaaa agttattggt gaagcggtta tccgtgaaac
    21361 cttcaaggtg tctaaagtgg gaactatcgg tggatttatg gttatcaacg gtaaggttgc
    21421 ccgtgactct aaagtccgtg ttatccgtga tggtgtcgtt atctatgatg gtgaactcgc
    21481 aagcttgaaa cactataaag acgacgttaa ggaagttaca aacggccgtg aaggtggatt
    21541 gatgatcgac tgctacaatg atattaagat ggatgatgtg attgaggcgt atgtcatgga
    21601 agaaatcaag agataagatt ttttgctcct ttcttaggtg gtgagggacg caagcaaacc
    21661 gatggtttca ttgcttattt ttgagcctag ggtctcaaaa atcccctgtg atgggactga
    21721 taaatcagtt ccatcacttt caccacggcg aaagaagcag atgacttcaa attgaacttc
    21781 gtttcaattt aaactgaaaa tcaagaagtt taaaatagct aggtctgctg gcctagcttt
    21841 tggttcaaag tagagaaagg aatatcatgg caaatcattt ccgtacagat cgtgtgggca
    21901 tggaaatcaa gcgtgaagtc aatgagattt tgcaaaagaa agtccgtgat ccacgtgtcc
    21961 aaggtgtgac catcacagat gttcagatgc tgggtgactt gtctgttgcc aaggtttatt
    22021 acaccatttt gagtaacctt gcttcggata accaaaaagc ccaaatcggg cttgaaaaag
    22081 caactggtac catcaaacgt gaacttggtc gcaatttgaa attgtacaaa atcccagatt
    22141 tgaccttcgt caaagacgag tccatcgagt atggaaacaa gattgacgag atgctacgca
    22201 atctggataa gaactaaaga agaggggttg cccctctttt ttggtggagg aaaataggtt
    22261 gaatttgaaa tggaaaaata ttctttta
//
LOCUS       DAVBOG010000033        22095 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.033, whole genome shotgun sequence.
ACCESSION   DAVBOG010000033 DAVBOG010000000
VERSION     DAVBOG010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 22095)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22095)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22095
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.033"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..245)
                     /locus_tag="VQ865_001423"
                     /pseudo
     CDS             complement(1..245)
                     /locus_tag="VQ865_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ865_001424"
     CDS             complement(629..1825)
                     /gene="tuf"
                     /locus_tag="VQ865_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014335040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3135751.1"
                     /translation="MAKEKYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLARRLPSSV
                     NQPKDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQM
                     DGAILVVASTDGPMPQTREHILLSRQVGVKHLIVFMNKVDLVDDEELLELVEMEIRDL
                     LSEYDFPGDDLPVIQGSALKALEGDSKYEDIVMELMNTVDEYIPEPERDTDKPLLLPV
                     EDVFSITGRGTVASGRIDRGIVKVNDEIEIVGIKEETQKAVVTGVEMFRKQLDEGLAG
                     DNVGVLLRGVQRDEIERGQVIAKPGSINPHTKFKGEVYILTKEEGGRHTPFFNNYRPQ
                     FYFRTTDVTGSIELPAGTEMVMPGDNVTIDVELIHPIAVEQGTTFSIREGGRTVGSGM
                     VTEIEA"
     gene            complement(2701..3570)
                     /locus_tag="VQ865_001425"
     CDS             complement(2701..3570)
                     /locus_tag="VQ865_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000348128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3135752.1"
                     /translation="MDFTWALKYATEFLGTAILIILGNGAVANVELKGTKGHQSGWIV
                     IAVGYGMGVMIPALMFGNVSGNHINPAFTLGLAVSGLFPWAQVVPYIIAQVLGAIFGQ
                     ALVVATYRPFYLKTEKPNNILGTFSTISSIDHGTKESRYAATVNGLINEFVGSFVLFF
                     AALGLTKNFFGAEVLQFMKQKAIEAGQTVDFSDLAIKAQVAPHTASGLSVAHLALGFL
                     VMALVTSLGGPTGPALNPARDLGPRLLHAFLPKSVLGEHKGDSKWWYSWVPVVAPIAA
                     AIAAVAVFKFLYL"
     gene            complement(3793..4473)
                     /locus_tag="VQ865_001426"
     CDS             complement(3793..4473)
                     /locus_tag="VQ865_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HET3135753.1"
                     /translation="MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKT
                     ENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRL
                     STPDKPTPEKPEIPSPQEPGTPGEPTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDK
                     PTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGF
                     FKKKEDEK"
     gene            complement(4431..5537)
                     /locus_tag="VQ865_001427"
     CDS             complement(4431..5537)
                     /locus_tag="VQ865_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001021424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HET3135754.1"
                     /translation="MNIILIAKLLRENRNTKANALNNGWVRSGSEEFKKFSHFVGVDK
                     GIVRTNVLTGKKLSDKIRKEVGSGDSKLGKGGYFSTGDVLLGKDVVSYTVQVFSENNE
                     RVGVNTQSHRVQYNLPILADFSVIQDTVEPSRTVVEKIIPKLNIPEEEKGKITEEIKK
                     KKKTSELAELILENVKVRYVDEQGRLLSLKNDTGIGEKESDGTYITNKKQLIGTSYNV
                     TDKKLSSMTTTDGKYYTFKEADTNSASLTGNIVSEGRTVTLVYRESEAPTTATVTANY
                     YKEGSQEKLAESVIKADLAIGSEYTTESKTIEGKTTTEDKEDRVITRKTTYTLVATPA
                     NAYQKTVQQLTITTVRMLRKQWFPKQQPLLRRRL"
     gene            complement(5497..5670)
                     /locus_tag="VQ865_001428"
     CDS             complement(5497..5670)
                     /locus_tag="VQ865_001428"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135755.1"
                     /translation="MKITYHVKDNQLEVETDKYTYTAARNGSKEVGIQESDIAATLSA
                     DEYNSNRQTFERE"
     gene            complement(5648..5902)
                     /locus_tag="VQ865_001429"
     CDS             complement(5648..5902)
                     /locus_tag="VQ865_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135756.1"
                     /translation="MLNVDQDFMSISKPNKSGSDWKKTFTVRTTNRLANDLNNVLKQV
                     DKDTPNTPTWLNSAASKAKDDDRVYKLLKTLIPGENYLSC"
     gene            complement(6260..6793)
                     /locus_tag="VQ865_001430"
     CDS             complement(6260..6793)
                     /locus_tag="VQ865_001430"
                     /inference="COORDINATES: protein motif:HMM:NF024751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3135757.1"
                     /translation="MTSFKEQEPEKVAEFLDILDNLKDLPIVYIDETGIDRYLYRPYA
                     RAPRGEKVYEKISGRRFERTSIVAGQVDGEFIAPMIYKKSMTSDFFVEWFKTQLLPAL
                     KTPHVIVMGNASFHPKNILDELCIQDKHFFLPLPPYSPDLNPIEQAWAILKKKVTDLL
                     REVPTIFECLECFFKTR"
     gene            complement(6780..6995)
                     /locus_tag="VQ865_001431"
     CDS             complement(6780..6995)
                     /locus_tag="VQ865_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3135758.1"
                     /translation="MGKERCEQGHIERKKRVVKNRKIPLEELKAFVEAHPDAFLREIA
                     AHFDCALPSVWAALKYIKVTLKKDDEL"
     gene            complement(6962..7105)
                     /locus_tag="VQ865_001432"
     CDS             complement(6962..7105)
                     /locus_tag="VQ865_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007285173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tnpB"
                     /protein_id="HET3135759.1"
                     /translation="MAYSTDFKQRALDSIKEGHSHVEAAKFFGVGVRTLFTWEKKDVN
                     KDT"
     gene            7339..9057
                     /locus_tag="VQ865_001433"
     CDS             7339..9057
                     /locus_tag="VQ865_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HET3135760.1"
                     /translation="MSYQENYQKWVDFVELPDYLRQDLENMDEKTKEDAFYTNLEFGT
                     AGMRGLVGAGTNRINIYVVRQATEGLARLIESKGGNEKERGVAIAYDSRHFSPEFAFE
                     SAAVLAKHGIKSYVFESLRPTPELSFAVRHLNCFAGIMVTASHNPAPFNGYKVYGEDG
                     GQMPPHDADALTTYIRAIENPFAVEVADVETEKASGLIEVIGEAVDVEYLKEVKDVNI
                     NPALIEEFGKDMKIVYTPLHGTGEMLARRALAQAGFDSVQVVEAQATADPDFSTVTSP
                     NPESQAAFALAEELGRQVGADVLVATDPDADRVGVEVLQKDGSYLNLSGNQIGAIMAK
                     YILEAHKNAGTLPENAALCKSIVSTDLVTKIAESYGATMFNVLTGFKFIAEKIQEFEE
                     KHNHTYMMGFEESFGYLIKPFVRDKDAIQAVLVVAELAAYYRSRGLTLADGIEEIYKE
                     YGYYAEKTISVTLSGVDGAEQIKAIMAKFRNNAPTEWNATAITVVEDFKAQTATVADG
                     TVTNLTTPPSDVLKYTLADGSWIAVRPSGTEPKIKFYIAVVGETNEESQAKIANIEAE
                     INAFVK"
     gene            9168..9515
                     /locus_tag="VQ865_001434"
     CDS             9168..9515
                     /locus_tag="VQ865_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HET3135761.1"
                     /translation="MEQFLDNIKDLEVTTVVRAQEALDKKETATFFIGRKTCPYCRKF
                     SGTLSGVVAETKAHIYFINSEEPSQLNDLQAFRSRYGIPTVPGFVHITDGQINVRCDS
                     SMSAQEIKDFAGL"
     gene            complement(9793..10629)
                     /locus_tag="VQ865_001435"
     CDS             complement(9793..10629)
                     /locus_tag="VQ865_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135762.1"
                     /translation="MKKWMLVLVSLMTALFLVACGKNSSETSGDNWSKYQSNKSITIG
                     FDSTFVPMGFAQKDGSYAGFDIDLATAVFEKYGITVNWQPIDWDLKEAELTKGTIDLI
                     WNGYSATDERREKVAFSNSYMKNEQVLVTKKSSGITTAKDMTGKTLGAQAGSSGYADF
                     EANPEILKNIVANKEANQYQTFNEALIDLKNDRIDGLLIDRVYANYYLEAEGVLNDYN
                     VFTVGLETEAFAVGARKEDTNLVKKINEAFSSLYKDGKFQEISQKWFGEDVATKEVKE
                     GQ"
     gene            complement(10642..11271)
                     /locus_tag="VQ865_001436"
     CDS             complement(10642..11271)
                     /locus_tag="VQ865_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000891751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HET3135763.1"
                     /translation="MLELRNINKVFGDKQILSDFSLSIPEKQILAIVGPSGGGKTTLL
                     RMLAGLETIDSGQIFYNGQPLELDELQKRNLLGFVFQDFQLFPHLSVLENLTLSPVKT
                     MGMKQEEAEKKASGLLEQLGLGGHAEAYPFSLSGGQKQRVALARAMMIDPEIIGYDEP
                     TSALDPELRLEVEKLILQNRELGMTQIVVTHDLQFAENIADVLLKVEPK"
     gene            complement(11281..11922)
                     /locus_tag="VQ865_001437"
     CDS             complement(11281..11922)
                     /locus_tag="VQ865_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HET3135764.1"
                     /translation="MSYLFEILPSLLNGASTTVQVFALVLLFSIPLGVLIAFALQVHW
                     KPLHYLINIYIWVMRGTPLLLQLIFIYYVLPSIGIRLDRLPAAIIAFVLNYAAYFAEI
                     FRGGIDTIPRGQYEAAKVLKFSPFDRVRYIILPQVTKIVLPSVFNEVMSLVKDTSLVY
                     ALGISDLILASRTAANRDASLVPMFLAGAIYLILIGIVTIISKKVEKKYSYYR"
     gene            complement(12068..13297)
                     /locus_tag="VQ865_001438"
     CDS             complement(12068..13297)
                     /locus_tag="VQ865_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HET3135765.1"
                     /translation="MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEG
                     IGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLAL
                     KADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRS
                     IYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQK
                     ATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQ
                     FSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLT
                     KWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTY
                     LKLVPDDVQMQELFERL"
     gene            complement(13287..14453)
                     /locus_tag="VQ865_001439"
     CDS             complement(13287..14453)
                     /locus_tag="VQ865_001439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000435446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HET3135766.1"
                     /translation="MEQKEKHFSLSWFFKWFLDNKAITVFLVTLLLGLNLFILSKISF
                     LFSPVLDFLAVVMLPVILSGLLYYLLNPIVDWMEKHKVNRVIAITIVFVIIALFIIWG
                     LAVAIPNLQRQVLTFARNVPVYLEDIDRIVNGLVAQHLPDDFRPQLEQVLTNFSSQAT
                     VLASKVSSQAVNWVSAFISGASQVIVALIIVPFMLFYLLRDGKGLRNYLTQFIPRKLK
                     EPVGQVLSDVNQQLSNYVRGQVTVAIIVAVMFIIFFKIIGLRYAVTLGVTAGILNLVP
                     YLGSFLAMLPALVLGLIAGPVMLLKVVIVFIVEQTIEGRFVSPLILGSQLNIHPINVL
                     FVLLTSGSMFGIWGVLLGIPVYASAKVVISAIFEWYKVVSGLYELEGEEVKSEQ"
     gene            14597..15610
                     /locus_tag="VQ865_001440"
     CDS             14597..15610
                     /locus_tag="VQ865_001440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HET3135767.1"
                     /translation="MKETVYFGTYTRRTSQGIYKADFDTETGQLSNLELFAAEPSPTY
                     LAFDQHQHLYTVGSQDDKGGIAAYQTDGTVLNHVVEEGAPHCYVAVDEKRDLVYAANY
                     HKGQVLVYKRQEDGSLLLSDMDQHSGQGPHENQASPHVHYTDLTPDHYLVTCDLGTDQ
                     VITYDLDQEGKLSKLYTYHSKPGAGSRHIIFHNHYKIAYLICELNSTIEVLIYDGVGE
                     FVRMQVISTLPEAYEGFNGTAAIHLSKDGKYLYASNRGHDSIAVYTILADGSLELLEI
                     VPTHGQTPRDFDLTPNQKFLIVVHQDSDNATVFKRNCDNGRLAELSNDFHVPEAVCIR
                     FAP"
     gene            complement(15655..16074)
                     /locus_tag="VQ865_001441"
     CDS             complement(15655..16074)
                     /locus_tag="VQ865_001441"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HET3135768.1"
                     /translation="MAQLTVQIVTPDGLVYDHHASYVSVRTLDGEMGILPRHENMIAV
                     LAVDEVKVKRIDDKDHVNWIAVNGGVIEIANDMITIVADSAERARDIDISRAERAKLR
                     AERAIEEAQDKHLIDQERRAKIALQRAINRINVGNRL"
     gene            complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ865_001442"
     CDS             complement(16085..17491)
                     /gene="atpD"
                     /locus_tag="VQ865_001442"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HET3135769.1"
                     /translation="MSSGKIAQVIGPVVDVLFAAGEKLPEINNALVVYKNDERKTKIV
                     LEVALELGDGMVRTIAMESTDGLTRGMEVLDTGRPISVPVGKETLGRVFNVLGDTIDL
                     EAPFTEDAERQPIHKKAPTFDELSTSSEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYWEMKESGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSVTSIQAIYVPADDYTDPAPATAFAHLDSTTNLERKLVQ
                     LGIYPAVDPLASSSRALAPEIVGEEHYAVAAEVKRVLQRYHELQDIIAILGMDELSDE
                     EKTLVARARRIQFFLSQNFNVAEQFTGQPGSYVPVAETVRGFKEILDGKYDHLPEDAF
                     RGVGSIEDVIAKAEKMGF"
     gene            complement(17577..18455)
                     /locus_tag="VQ865_001443"
     CDS             complement(17577..18455)
                     /locus_tag="VQ865_001443"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002895995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HET3135770.1"
                     /translation="MAVSLNDIKTKIASTKNTSQITNAMQMVSAAKLGRSEEAARNFQ
                     VYAQKVRKLLTDILHGNGAGASTNPMLISRSVKKTGYIVITSDRGLVGGYNSSILKAV
                     MELKEEYHPDGKGFEMICIGGMGADFFKARGIQPLYELRGLADQPSFDQVRKIISKTV
                     EMYQNELFDELYVCYNHHVNTLTSQMRVEQMLPIVDLDPNEADEEYSLTFELETSREE
                     ILEQLLPQFAESMIYGAIIDAKTAENAAGMTAMQTATDNAKKVINDLTIQYNRARQAA
                     ITQEITEIVAGASALE"
     gene            complement(18471..19976)
                     /locus_tag="VQ865_001444"
     CDS             complement(18471..19976)
                     /locus_tag="VQ865_001444"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011889023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HET3135771.1"
                     /translation="MAINAQEISALIKQQIENFKPNFDVTETGVVTYIGDGIARAHGL
                     ENVMSGELLNFENGSYGMAQNLESTDVGIIILGDFTDIREGDTIRRTGKIMEVPVGES
                     LIGRVVDPLGRPVDGLGEIHTDKTRPVEAPAPGVMQRKSVSEPLQTGLKAIDALVPIG
                     RGQRELIIGDRQTGKTTIAIDTILNQKDQDMICIYVAIGQKESTVRTQVETLRQYGAL
                     DYTIVVTASASQPSPLLFLAPYTGVAMAEEFMYQGKHVLIVYDDLSKQAVAYRELSLL
                     LRRPPGREAFPGDVFYLHSRLLERSAKVSDELGGGSITALPFIETQAGDISAYIATNV
                     ISITDGQIFLGDGLFNAGIRPAIDAGSSVSRVGGSAQIKAMKKVAGTLRIDLASYREL
                     EAFTKFGSDLDAATQAKLNRGRRTVEVLKQPVHKPLPVEKQVTILYALTHGFLDTVPV
                     DDIVRFEEEFHTFFDAQHPEILETIRDTKDLPEEAVLDAAITEFLNQSSFQ"
     gene            complement(19991..20527)
                     /locus_tag="VQ865_001445"
     CDS             complement(19991..20527)
                     /locus_tag="VQ865_001445"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HET3135772.1"
                     /translation="MDKKTVKVIEKYSMPFVQLVLEKGEEDRIFSDLTQIKQVVEKTG
                     LPSFLKQVAVDESDKEKTIAFFQDSVSPLLQNFIQVLAYNHRANLFYDVLVDCLNRLE
                     KETNRFEVTITSAHPLTDEQKTRLLPLIEKKMSLKVRSVKEQIDESLIGGFVIFANHK
                     TIDVSIKQQLKVVKENLK"
     gene            complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ865_001446"
     CDS             complement(20527..21021)
                     /gene="atpF"
                     /locus_tag="VQ865_001446"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HET3135773.1"
                     /translation="MHVTVGELIGNFILITGSFILLLVLIKKFAWSNITGIFEERAEK
                     IASDIDRAEEARQKAEVLAQKREDELAGSRKEAKTIIENAKETAEQSKANILADAKLE
                     AGHLKEKANQEIAQNKVEALQSVKGEVADLTISLAGKIISQNLDSHAHKALIDQYIDQ
                     LGEA"
     gene            complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ865_001447"
     CDS             complement(21035..21751)
                     /gene="atpB"
                     /locus_tag="VQ865_001447"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000392848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HET3135774.1"
                     /translation="MEESINPIISIGPVIFNLTMLAMTLLIVGVIFVFIYWASRNMTL
                     KPKGKQNVLEYVYDFVIGFTEPNIGSRYMKDYSLFFLCLFLFMVIANNLGLMTKLQTI
                     DGTNWWSSPTANLQYDLTLSFLVILLTHIESVRRRGFKKSIKSFMSPVFVIPMNILEE
                     FTNFLSLALRIFGNIFAGEVMTSLLLLLSHQAIYWYPVAFGANLAWTAFSVFISCIQA
                     YVFTLLTSVYLGNKINIEEE"
     gene            complement(21786..21986)
                     /locus_tag="VQ865_001448"
     CDS             complement(21786..21986)
                     /locus_tag="VQ865_001448"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015545704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HET3135775.1"
                     /translation="MNLTFLGLCIACMGVSVGEGLLMNGLFKSVARQPDMLSEFRSLM
                     FLGVAFIEGTFFVTLVFSFIIK"
BASE COUNT         6571 a         4740 c         4031 g         6753 t
ORIGIN      
        1 gtcatatatg catggttacg accaccacgt gtttcttgaa ggagagagtc gagtccgaac
       61 tcctcatatt tttttacgtt tcgccaaatc gttgtttgat tacagtctaa aagctctata
      121 atctcttaat aagatttgcc catcagacga aatagaacga tttgaaggcg tttatgatat
      181 ttagctgtac gagagtcttt taaaagtgtt ttgatggttt tgatttcttc tttagttgat
      241 ttcatattac tattgtataa tgctttttga tttgagtcta gtattatact cttcgaaaat
      301 ctcttcaaac cgcgtcagct tcgccttgtc gtatagatgt tactgacttc gtcagttcta
      361 tctacaacct aaaaacagtg ttttgaacag tctgcagcta actttctata acaaaatgaa
      421 ataagaacaa gacaaatcaa tcaagacaat caaatcgatt tctaacaatg ttttagaagt
      481 agatgtgtac tattctagtt tcaatatatt atagtttgct ctttgatttt cattgagtat
      541 tagttcaata tctaaaaaaa gaaccttgcc aagcaagatt cttttagtgt ctaacttaaa
      601 taattgttct tctgggaact aaatcgaatt aagcttcgat ttctgtaacc atacctgaac
      661 caacagtacg tccaccctca cggatagaga atgtagtacc ttgttctacg gcgattgggt
      721 gaatcaactc aacgtcgatt gtcacgttat caccaggcat taccatttca gtacctgctg
      781 gaagttcgat tgaacctgta acgtcagtag tacggaagta gaattgtgga cggtagttgt
      841 tgaagaatgg agtgtgacgt ccaccttctt ctttagtaag gatgtagact tcacctttga
      901 atttagtgtg tgggttgatt gaacctggtt tagcgataac ttgtccacgt tcgatttcat
      961 cacgttgaac accacgaaga aggacaccta cgttatctcc agcaagacct tcgtcaagtt
     1021 gtttacggaa catttcaaca ccagtaacaa ctgctttttg agtttcttct ttgataccaa
     1081 cgatttcgat ttcgtcgttg actttaacga taccacggtc gatacgtcct gaagcaactg
     1141 taccacgtcc agtaattgag aatacgtcct cgactggaag aagcaatggt ttgtcagtgt
     1201 cacgttctgg ttctgggata tactcatcaa ctgtgttcat caattccata acgatgtctt
     1261 cgtatttaga gtcaccttca agagctttaa gtgctgaacc ttggataact ggaagatcgt
     1321 cacctgggaa gtcgtattct gacaataggt cacggatttc catttcaacc aattcaagca
     1381 attcttcgtc gtcaaccaag tcaactttgt tcatgaagac gataaggtgt ttaacaccaa
     1441 cctgacgtga aagaaggatg tgctcacgag tttgtggcat tggtccgtca gttgaagcta
     1501 ctacaaggat agctccgtcc atttgagcag caccagtgat catattttta acgtagtccg
     1561 cgtgtcctgg agcgtcgatg tgagcgtagt gacgtttttc agtttcgtac tcaacgtgcg
     1621 cagtgttgat agtgataccg cgttcgcgtt cttctggagc agcatcgata gacgcatagt
     1681 ctttaggttg gttaactgat gaaggcaagc gacgtgccaa aacagttgtg atagctgcag
     1741 ttagggtagt tttaccgtgg tcaacgtgtc cgatagtacc aatgttaacg tgtggtttac
     1801 tacgatcgta tttttctttt gccatttgag taaaagcctc caataaaata tattttatag
     1861 atagacagta ggcaatacag tctaactttc cttactattt tatcaaattt cagctaaatt
     1921 gcaagtgttt tacaacgttt ttgtgaatta ttcttggtaa aaatttaact aactaataga
     1981 aagtactaaa tagacttatc cttcaaggag ttttcagcat tatccatcca ctcacttgct
     2041 gaaaatgtaa acagtctctg gtttatatag taaaatgaaa caagaatagg gcaaatcgat
     2101 caggacaatc aaatcgattt ctaaaaatgt tttagaagta gaggtgtact attctagttt
     2161 caatctacta tacaacctca aaactgtgtt ttgaacaacc tgcggctagc ttcttagttt
     2221 gccctttgat tttcattgag tataaaattg cagataaaac gataacaatc ataggactca
     2281 gcagagtcaa tgtaggtcga agaatagccc ccctaatcgc ttattttata gcaaaatgaa
     2341 atagaaactg aacattttgt tgaggaaggt aaatcaattc ctcacaatgt ttgagaaaga
     2401 agggaggact attccaactt caacccacta ttaatatata atagaatgaa aactgcacaa
     2461 tttgattgga gaattcaaac caatttctaa caatgtttta gaaacaaggg tctattattt
     2521 caactgcaac ctactatagc ccattgaagc tggaatagcc cactgagact tctaaaccac
     2581 tgctggagag gagtttgttt agagtttctt tcatttccct aaaaaatcaa aaagagagaa
     2641 ccagtctgat cctctcttac ttatagatgg tgctcactca aatgttaaag gagctatttc
     2701 ttagagataa aggaatttga atacagctac tgccgcaatt gctgctgcga taggtgctac
     2761 tactggtacc caagaatacc accattttga atcgccttta tgctcaccaa gaactgattt
     2821 tggaaggaaa gcatgaagga gacgtggtcc caagtcacgg gctgggttca aggcgggtcc
     2881 tgtaggtcct ccaagtgatg ttaccaaagc cataacgagg aatccaagtg ccaagtgagc
     2941 cacagaaagt cctgaagcag tgtgtggagc cacctgtgct ttaatagcca agtcagaaaa
     3001 atcaactgtt tgtcctgctt ctattgcctt ttgtttcatg aattgaagca cttcagcacc
     3061 aaagaagttt ttagtcaaac caagagctgc aaagaacaaa acaaatgaac caacaaactc
     3121 attaatcaaa ccattgacag ttgctgcata gcgactttct tttgtaccat ggtcaatact
     3181 tgaaatagtt gagaaagttc ccaagatgtt atttggtttt tcagttttca agtagaatgg
     3241 acggtatgtt gccacaacta aggcttggcc aaagatagcc cccaagactt gcgcgataat
     3301 gtaaggtacc acttgtgccc aagggaaaag accgctaact gcaagcccta gagtgaaagc
     3361 agggttgatg tgattcccag atacgttacc aaacatcaag gctgggatca taacccccat
     3421 accataacca acagcgatga cgatccagcc actttggtga cctttcgtac ctttaagttc
     3481 aacgttggca actgcaccat tcccaagaat gatcaaaatg gcagttccca aaaattcagt
     3541 ggcatacttc agtgcccatg tgaaatccat ttgctagatt ctccttaaaa ttttttagat
     3601 attccttatt ttatcaattt ttaccctatt tagcaactga tttctggaaa tatttttaaa
     3661 aaaataggat tcatagtttc ctagttcaac gtacttgtaa gcgtttttat tcttcacgaa
     3721 agacctcatt ctcaaaacca ggaaaaagcc cacatctgtg atcttttcct tgttcctaga
     3781 ttctaaaatc tattattttt catcttcttt tttcttgaag aatcctaatc ctagaccagc
     3841 taacaaggtc atgataccag cactagccaa ggtagcatta gcttctgtac ctgtgtttgg
     3901 caattcctct ctcttacctg tctcataagt cggaacttct gggtctggat tcactggagt
     3961 ttcagttttt ggagtacctg gttctggagt tggtttatct ggtgttggag tctcttgatt
     4021 tggtagttct gggtttggtg tcggaacact tggatgctct ggatttggtt gtgggattgg
     4081 tttttctgga gtcggttcac ctggagtacc tggttcctga ggacttggaa tttctggttt
     4141 ttctggagtt ggtttatctg gtgttgataa acggtcatac cttaccgtta tttctttatc
     4201 actagagtct gacgtaactt cttgtgattc aactgttgga atatctggat ctttgtactt
     4261 gtcaatctta ccagatataa cctcgtccca gtttcctgtt gtccattcac cgtaggttac
     4321 aactcccgtg accttgttct cagtttttgt acggcttaag gttacaggtt gaacaacatc
     4381 ttcttttaca ttttggttcg taactttatc aacgtaatga atgatacgcg ttatagtctt
     4441 cgtctcagta gaggttgctg ttttgggaac cactgtttcc tcaacattct cacggtagta
     4501 atagtcaact gttgcaccgt cttctggtac gcatttgcag gagttgctac caaggtgtat
     4561 gttgttttcc ttgtgataac tcggtcttct ttgtcctcag ttgttgtttt cccttcaata
     4621 gtttttgatt ctgtggtata ctcagaacct atcgctaaat cagcttttat aacagactct
     4681 gccaacttct cttggctacc ttctttatag taattggctg ttactgtagc agtggttggc
     4741 gcttcgcttt ctctataaac taaggtcact gttctacctt cgcttacaat attcccagtt
     4801 aaacttgcag aatttgtatc tgcttcttta aaagtataat attttccgtc agtagtagtc
     4861 atgctactga gttttttatc tgtgacattg tagctggtac caatcagttg ttttttattg
     4921 gtaatgtagg ttccgtcact ttctttttct ccaattccag tatcattttt caatgatagc
     4981 aaacgccctt gttcatcaac atagcgaact ttcacatttt ctaagattag ttctgccaat
     5041 tctgaggttt ttttcttttt cttgatttct tcggttattt tccctttctc ttcttcggga
     5101 atatttagtt ttggaatgat tttttcaaca acggttcgtg atggttccac agtatcttgg
     5161 atgactgaaa agtcagctag aattgggaga ttatactgaa cacggtgact ttgagtgttt
     5221 actcctactc tttcattatt ctctgaaaat acttgtacgg tataagaaac aacatctttt
     5281 cctaatagaa catccccagt agagaaatag ccgccttttc ctagtttgct atctccagag
     5341 cccacttctt tcctaatctt atcagatagt tttttaccag tcagtacatt cgttcgcaca
     5401 atccctttgt ctacccctac aaagtgggag aactttttga actcttcaga accagatcta
     5461 acccaaccat tattaagggc atttgctttt gtatttctat tctctctcaa aagtttggcg
     5521 attagaatta tattcatcgg cacttagagt tgctgctata tctgactctt gaataccaac
     5581 ttccttacta ccatttctag cggcagtata tgtgtattta tctgtttcta cttctagctg
     5641 attatcctta acatgatagg taattttcac ctggtataag agtcttcagt agtttatata
     5701 ctctgtcatc atctttagct ttagaagcag ctgagtttag ccaagttggg gtattaggag
     5761 tatctttatc aacctgtttc aagacattat tcaagtcatt tgctagccta ttggttgtcc
     5821 tcactgtgaa agttttcttc cagtctgaac cacttttatt aggcttagat atgctcatga
     5881 aatcctggtc aacattcaac acaatatcgc cttgtttttt agcatcttcc gttgcttctg
     5941 cttcaaattg atcatggagt ttttgttgct ctggtgtata gtttttttat ttacacgatt
     6001 taatgtacta ttttttattt tagtattaag aactccatta atacgatttt taaattctgc
     6061 ttcaaaaaat cccttaattt gttggtgcgc aagttcaaca ttcaaacctt tcttatacaa
     6121 gtcttcattc tgatacaagt cttcattctg aacgatttcg gctacacggt gaatggtttg
     6181 attgtatacc gtcttctctt aaccagcagt atccttagtt ttaatgacta ctcgataggt
     6241 tcctttagaa ccgttatagt catctagttt taaaaaagca ttccaaacat tcaaaaatag
     6301 ttggaacttc ccttaataaa tccgtcactt tctttttcaa gatagcccaa gcttgctcaa
     6361 taggattcaa atccggtgaa taaggtggta gaggtaagaa aaagtgttta tcttggatgc
     6421 agagttcatc caaaatgttc ttgggatgaa aactagcatt gcccatgaca ataacatgag
     6481 gtgtcttcaa agcaggtagg agttgcgttt tgaaccactc cacaaagaaa tcgcttgtca
     6541 tgcttttctt gtaaatcatg ggagctataa actctccgtc tacttgtcct gcaacaattg
     6601 aagttcgctc aaaacgacgt ccgctaatct tttcatagac tttctcccct ctaggagccc
     6661 gtgcataagg acgatagagg tagcggtcga ttcctgtttc atcaatatat acgattggta
     6721 aatcttttag gttatccaaa atatcaagaa actcagcgac tttctctggc tcttgttcct
     6781 taaagctcgt catctttttt taaagtgacc ttaatatact ttaaagctgc ccatacggag
     6841 ggcagagcac aatcaaaatg tgccgcaatt tcccgtaaaa aagcatctgg atgagcctct
     6901 acaaaggctt tcaattcctc taaaggaatc tttcggtttt tgacgactcg ctttttcctc
     6961 tctatgtgtc cttgttcaca tctttctttt cccacgtgaa gagagttctg acgccaacac
     7021 caaaaaactt ggctgcctcg acatggctgt gcccctcttt gatggaatct aatgctcgct
     7081 gtttaaaatc agtactatat gccatagctt tattataata tgcttgttta aaactaagca
     7141 actatatcaa tgttttgtta ttagaagact tacttttttt actgaaatcg aatttttcct
     7201 aacctcaaca tcatataacc ccaaaattca atctgacctg gtttgaagag atgttcgaag
     7261 cagataaggt tttactaaaa ctaaaaaaaa tgatataatc aaactgatta aatgttttaa
     7321 aaataaagga gaatttgaat gtcttaccaa gaaaattacc agaaatgggt tgattttgtg
     7381 gagcttcctg actaccttcg tcaagatttg gaaaatatgg acgaaaaaac taaggaagat
     7441 gccttctata caaatcttga atttggtact gcaggtatgc gtggcttggt tggtgctggt
     7501 acaaaccgta tcaacatcta cgttgttcgc caagctactg aaggattggc tcgtttgatt
     7561 gagtcaaaag gtggaaacga gaaagaacgc ggtgtagcaa ttgcctacga tagccgtcac
     7621 ttctcacctg agtttgcctt tgaatctgcg gcagttcttg ctaaacacgg catcaaatct
     7681 tacgtatttg aaagccttcg tccaactcca gaactatcat ttgcagttcg tcatctcaac
     7741 tgtttcgcag gtatcatggt cacagccagc cacaaccctg ctccatttaa cggttacaag
     7801 gtttacggtg aagacggtgg acaaatgcct ccacacgatg cggacgcttt gactacttat
     7861 atccgtgcaa tcgaaaaccc atttgcagtt gaagttgctg atgtggaaac tgaaaaagct
     7921 tctggcttga ttgaagttat cggcgaagct gttgacgtag aataccttaa agaggttaag
     7981 gacgtaaaca tcaacccagc cttgattgaa gaatttggta aagacatgaa gattgtctac
     8041 acaccacttc atggtactgg tgaaatgttg gctcgtcgtg ctcttgccca agcaggattt
     8101 gactctgttc aagttgttga agcgcaagca actgctgacc cagacttctc aactgtaaca
     8161 tctccaaacc cagaaagcca agcagccttt gcccttgctg aagaacttgg tcgtcaagtt
     8221 ggtgcagatg ttcttgtcgc aactgaccca gacgctgacc gtgttggtgt tgaagttctt
     8281 caaaaagatg gtagctacct caacctttca ggtaaccaaa tcggtgctat catggctaaa
     8341 tacatcttgg aagctcacaa aaacgctgga actcttcctg aaaatgccgc tctctgcaaa
     8401 tctatcgttt caactgactt ggtaacgaag attgctgaaa gctacggcgc aactatgttc
     8461 aacgtcttga caggtttcaa atttatcgct gaaaaaatcc aagaattcga agaaaaacac
     8521 aaccacactt acatgatggg atttgaagaa agcttcggtt acttgattaa accatttgta
     8581 cgtgataaag atgccatcca agccgttctt gtcgttgctg aacttgctgc ctactaccgt
     8641 tctcgtggtt tgacacttgc tgacggtatc gaagaaatct ataaagaata tggctactac
     8701 gcagaaaaaa caatctctgt tactctttca ggtgtcgatg gtgctgaaca aatcaaagcg
     8761 attatggcta aattccgcaa caatgctcca acagaatgga acgcaacagc tatcactgtc
     8821 gtagaagact tcaaggcaca aactgctact gttgctgacg gtactgttac aaacttgaca
     8881 actcctccaa gtgatgtgtt gaaatacaca cttgctgacg gttcatggat tgccgttcgc
     8941 ccttcaggta cagaaccaaa aatcaagttc tacattgcag ttgtagggga aaccaacgaa
     9001 gaatcacaag ctaagattgc taacatcgaa gcagaaatca atgcatttgt aaaataaaga
     9061 cctataaaag atgagaccaa ccaacctcat cttttttcgt atcaaatcta agcaatttta
     9121 gaaactttat ggcatactag acttatcaat gaaagcgagg taatctcatg gaacaatttt
     9181 tagataacat caaagacctt gaagtcacta cagttgtgcg tgcgcaagaa gctcttgata
     9241 aaaaagaaac tgcaaccttc tttatcggtc gcaaaacttg cccttactgc cgtaaatttt
     9301 caggtacatt gtcaggtgtc gtagctgaaa ccaaagctca catttacttc atcaatagtg
     9361 aagaaccaag ccaactcaat gatttgcaag cattccgctc acgctatgga atcccaactg
     9421 taccaggttt tgttcatatt acagatggac aaatcaacgt ccgttgcgac tcttcaatgt
     9481 cagcacaaga aatcaaagat ttcgcaggat tgtaaaaaat cagctaacaa gtcttaaaat
     9541 cacaaaaacg cataatgtaa ggtgcaaaaa ccttgatatt atgcgtttta ttgttcctaa
     9601 aacagttaca tcagcatttc attacagaac attttaattt tggaagtcaa atcaattttt
     9661 aacaatgttt tagaaatcac agtgggctat tccatattca attatccaga ttcaatcgct
     9721 attatcgttt tcctagatta caaaaaaact acgttttgct aatcaaaacg cagtttcagc
     9781 cactatttta tcttactgtc cttcttttac ttctttggtt gctacatctt ctccaaacca
     9841 tttttgactg atttcttgga acttgccgtc cttgtaaaga ctagaaaaag cttcatttat
     9901 cttcttaacc aagtttgtat cttccttacg ggctccaacc gcaaaagctt ctgtttctag
     9961 tccaactgta aagacattat aatcgtttaa aacaccttct gcttctaaat aataatttgc
    10021 atagacacgg tcaatcaata gaccatcaat tcgatcgttt ttcaaatcaa tcaaggcttc
    10081 attaaaggtt tggtattgat tcgcttcctt attagcgaca atattcttca aaatttctgg
    10141 atttgcttca aagtccgcat aaccagatga accagcttga gctcctaatg tctttccagt
    10201 catatccttt gcagtcgtga taccagatga tttcttcgta accaatacct gctcattctt
    10261 catatatgag ttactgaaag ccaccttttc acggcgttcg tctgtagcgg aatagccatt
    10321 ccaaatcaga tcaatcgttc cttttgtcaa ttcagcttct ttcaaatccc aatcaatcgg
    10381 ttgccaattt accgtgattc cgtatttttc aaaaacagct gtagctaaat caatatcaaa
    10441 tcctgcataa gaaccatctt tctgagcaaa tcccattgga acaaaagtac tatcaaatcc
    10501 aatagtaata gacttgttag actggtactt tgaccaatta tctccactag tttcgctaga
    10561 atttttccca caagctacta agaacaaagc agtcatcaga ctgactaata caagcatcca
    10621 ttttttcatc catttttcct cctatttagg ttctactttc aataatacat ctgcgatatt
    10681 ttcagcaaac tgcaaatcat gggtaaccac aatctgggtc atcccaagtt ccctattttg
    10741 caagattagc ttctccactt ccaaacgtaa ttctggatcc agggcagaag ttggttcatc
    10801 gtagccaatg atttctgggt caatcatcat agcacgcgcc aaagccaccc gctgcttttg
    10861 cccaccagat agtgagaaag gataggcctc tgcgtgtcct cctagtccta actgttccaa
    10921 gagtccactc gccttcttct cagcctcttc ctgcttcatt cccatggtct tcacaggcga
    10981 taaagtcaaa ttttccagaa ctgatagatg aggaaatagt tgaaaatctt ggaagacaaa
    11041 tcccagtagg ttgcgcttct gcaattcatc tagctctaaa ggttgtccat tataaaagat
    11101 ttgccctgaa tcaatggttt caagacctgc aagcatacgt aaaagagttg tcttacctcc
    11161 accagaaggt ccaacgatag ccaggatttg cttttcagga atacttagac tgaaatcaga
    11221 caggatttgt ttgtctccaa agactttatt gatatttcgt aattctaaca tagctgcccc
    11281 ctatctataa taactgtact ttttctcaac ttttttggaa ataattgtca caatcccaat
    11341 taaaatcaag taaatggctc ctgccaagaa cataggaacc agactagcat cgcggttagc
    11401 agctgttcga ctagccaaga taaggtctga aattccgaga gcatagacca aagaagtatc
    11461 cttgaccaaa ctcataactt cattaaagac actaggaaga acgatcttgg tcacttgggg
    11521 caagataata tagcgcactc tgtcaaaagg gctaaacttc aagaccttgg cagcctcata
    11581 ctgtcctctt ggaatagtgt caattccccc acggaaaatt tctgcaaagt aagctgcata
    11641 gttgagaaca aaggcaataa tagctgcagg aaggcgatct aaacgaatcc caatacttgg
    11701 gagcacataa tagataaaaa tcagttgcaa gagtaagggg gttcctcgca taacccagat
    11761 gtaaatgtta atcagataat ggaggggctt ccaatggact tgcaaggcaa aggcaatcaa
    11821 aacgcccaag ggaatcgaaa atagcaagac cagtgcaaag acctgtacag tcgtgctcgc
    11881 accattcagt aaactcggta atatctcaaa taaataagac atactgcacc tcctaaaagt
    11941 aattgttcct attatagcat gaataaacaa gattaccaag tatttttgta aaaagattct
    12001 accatataca aataaaaacc gtagctatca aaagagataa actacagttc tatatgttta
    12061 aacattctta caatctctca aacagttctt gcatttgcac atcatctgga accagtttta
    12121 agtaagtgtg agcatggact tttgcttctt caaaatgtcc caattcacgc aagagataga
    12181 tatagtgttc cagaaattct ggattgtcct tcaaatctcc tgtcaactct tgataatgct
    12241 cataagcagt atccaaatcg tccatttctt gataagaacg agcaatcatc cacttggtca
    12301 aaagattttc tggctcctca ctctgcaagt ctagaatatc ctcataacgc tcctgctcca
    12361 gataaatagt ggctaaacga agcaagattt cttctgtatc ctcagcgtct tcttttgcag
    12421 taaggagata attttctgca ccactagcat catgcaattc ataagaaaat tgtgaagcag
    12481 ctagcaagag gcgagtttca aagggatttt tctctaatcc ttgcttagcg atacgcaggg
    12541 cttcttgaac ttgatgttcc ttatgtaaag cctgactgta cccatactca tagccttcaa
    12601 agtcaggaga aatggtatca agctgcttaa agtagagggt ggctttttga tattcttctt
    12661 gatcaaaata aagactggcc aactcaaaag ctgttaagtc atcgtattct aactccaggg
    12721 ctttttctaa aaactcagta gccgtttcaa atttccctaa ctgagcatag gcaaagccaa
    12781 ttcgttgata ggtggaaatg cccgtttgct cataaatcga gcgattatct aactgggcat
    12841 aggcttgaat agccgcttgg taattttcca actcactatc caactctgcc aaacccaata
    12901 tcaagagaga atcctctgag taggtcaagg cctccaataa tttctcacgt gccacatctg
    12961 tcaaaccttc cagctggtaa aggtctgcct tcagagccaa agacgagaca taccagtcac
    13021 tgtcagcttg gatttcctca agataggtaa aggcttcttc tatttgacca tcctcgctag
    13081 caattgcagc tagattaaga tgaacctctg gaaaatcctc tacaattttc aggtaaattt
    13141 ccttggcctg aggatagaaa ccaatccctt caagataagt tgccaactca tacagaagat
    13201 cacttgaatc attttctaaa gctttggcga aataatgctc agccttagtt aaatcttgct
    13261 cctccaaagc ctgtaacatc tgttgactat tgttcactct tgacttcctc accctctaat
    13321 tcatatagac cactgactac cttataccat tcgaaaatgg ctgaaatgac aaccttagca
    13381 gaggcataaa ccggaatacc aagtaaaact ccccagatac caaacataga tcctgaagtt
    13441 aacaaaacaa agagaacatt aataggatgg atgtttaatt gacttcccaa aatcaatgga
    13501 gagacaaaac ggccttcaat agtttgttct acaataaaga caatcactac tttcaaaagc
    13561 atgactggac cagcaatcaa acccaatact agggcaggaa gcatggctag aaagctacca
    13621 agataaggga ccagatttaa aataccagca gtaaccccca gcgtaaccgc atagcgtaga
    13681 ccaataatct tgaagaagat gataaacatt actgctacaa taatagccac tgtcacttgc
    13741 cctcgaacat agttggacaa ctgttgattc acatctgata gaacttgtcc aacaggttcc
    13801 ttcaattttc ttggaatgaa ttgggtcaaa tagttacgca agcctttccc atcacgcaag
    13861 agataaaaga gcatgaaagg aacgataatc aaggcaacaa tcacttgaga agctccgcta
    13921 ataaaggcac tcacccagtt gactgcctga gatgaaacct tacttgccaa aactgtagcc
    13981 tggctagaaa aattggtcaa aacttgctct aattgaggtc tgaaatcatc tggcaggtgc
    14041 tgggctacca atccattaac aatcctatct atatcttcta agtaaacagg aacgtttctt
    14101 gcaaaggtca aaacctgacg ttgcagattt ggaatggcga ctgccaagcc ccaaatgata
    14161 aagagagcga tgataacaaa gacaatagtg atagctataa cacgattaac cttatgcttc
    14221 tccatccaat caacaatagg attcaacaaa taatataaca aaccagacaa aatgactggc
    14281 aacatcacaa ctgctaaaaa gtctaaaaca ggtgaaaata gaaaactaat cttacttaaa
    14341 ataaaaagat tcagtcccaa taataaggtt actaaaaata ccgtaattgc cttgttatct
    14401 aaaaaccact tgaaaaacca agataggcta aaatgtttct ctttttgctc cataaatact
    14461 tcctttctat tgtcctctca ttataccatt tttgaaacaa aataactctt ttttaaagtg
    14521 cttacatcta attggatatc tttaatttac ttgtttttgt gatataatag tcttatcttt
    14581 acacagaggt atagtaatga aagaaactgt ttattttgga acttatacac gtcgtacttc
    14641 tcaagggatt tacaaggcag actttgatac agaaactggt cagctttcaa atctagaact
    14701 ttttgcagct gagccaagtc caacctacct tgcctttgac cagcaccaac atttatacac
    14761 tgttggtagc caagacgata aggggggaat tgcagcctat caaactgacg ggactgtgtt
    14821 aaatcatgtt gttgaagaag gagctcccca ctgttatgtt gctgtcgatg aaaagcgtga
    14881 tttggtttac gcagccaact atcacaaggg acaagtcctt gtttataaac gccaggaaga
    14941 tggtagtctt ctacttagtg atatggatca acacagtggc caaggtccac atgaaaatca
    15001 agcttccccc catgttcact atacagattt aacacctgac cactatctag tgacctgcga
    15061 cttgggaact gaccaagtca tcacctatga cctcgatcaa gaaggaaaat tatctaagct
    15121 ctatacctat cacagcaagc caggagcagg ctcacgccat atcattttcc ataaccacta
    15181 taaaatcgct tatctcattt gtgaactcaa tagtactatc gaagttttaa tctacgatgg
    15241 cgttggcgaa tttgtacgta tgcaggttat ttcaacttta ccagaagctt acgaaggctt
    15301 taatggaacc gctgctattc atctctctaa agacggtaaa tacctctacg cttctaaccg
    15361 tggccatgat tctatcgcag tatataccat ccttgcggac ggtagcttag agttattaga
    15421 aatcgttcca acgcatggtc agactccacg tgattttgat ttgacaccca accaaaaatt
    15481 tctcattgtt gtccatcaag actctgacaa tgcaactgtc tttaaacgta attgtgacaa
    15541 tggtcgtcta gcagaactct ccaacgactt ccatgttccc gaagcagtct gcatccgttt
    15601 tgctccttaa aacaccataa aaaatgaact tggtattttc aagttcattt tttcttatag
    15661 tctatttccg acattaatac ggttaatggc acgttgcaaa gcaatcttag cacgacgttc
    15721 ttggtcaatc aaatgtttgt cttgtgcttc ttcaattgca cgttctgcac gaagtttggc
    15781 acgttctgca cgactgatat cgatatcacg agcacgttct gcagagtcag cgacgattgt
    15841 gatcatatca ttggcaattt caataacgcc accgtttact gcaatccagt tcacgtgatc
    15901 tttatcatcg atacgtttta cctttacttc atcaactgct aaaaccgcaa tcatattttc
    15961 atgtcgtggc aagatcccca tctcaccatc cagagttcga accgatacat agctggcatg
    16021 gtgatcatag acgagaccat ctggtgtcac gatctggaca gttaactgag ccataggtca
    16081 cctcttaaaa tcccattttt tcagcttttg caatcacatc ttcgatagaa cctacaccac
    16141 ggaaggcatc ttctggcaag tggtcgtatt taccatcaag gatttcctta aagccacgta
    16201 cagtttcagc aactggaaca taagaacctg gctgaccagt aaattgttcc gcaacgttga
    16261 agttttgtga caagaagaac tggatacgac gggcgcgagc aaccaaggtc ttttcttcat
    16321 cagaaagctc atccatacca aggatagcaa tgatatcttg caattcatgg taacgttgaa
    16381 ggacacgttt tacttcagca gcaactgcat agtgctcttc tccaacgatt tcaggtgcca
    16441 aggcacgtga gcttgaagca agtgggtcaa cggctgggta gatacccaat tgtaccaact
    16501 tacgttccaa gtttgttgtt gaatccaagt gagcgaaggc tgttgctggc gctgggtcag
    16561 tatagtcatc cgctggcaca tagatagcct ggatagaggt tacagaaccc ttcttggttg
    16621 atgtgatacg ttcttgcaat tgacccattt ccgtagcaag tgttggttgg taaccaacgg
    16681 ctgatggcat acgacccaaa agggcagata cttctgaacc agcctgagtg aaacggaaga
    16741 tattatcgat aaagagaagc acgtcttggc cttccacatc acggaagtat tcagcgattg
    16801 tcaaaccagt aagggcaaca cgcatacgtg ctcctggtgg ctcattcatc tgaccaaaga
    16861 ccatggctgt tttctcgata acgcctgatt ctttcatttc ccagtaaagg tcattcccct
    16921 cacgagtacg ttccccaaca ccagtaaata ctgaaatacc accgtgctct tgggcaatgt
    16981 tgtgaatcaa ttcttggatt aagacggttt taccaactcc ggcaccaccg aaaagtccaa
    17041 ctttaccacc tttaaggtaa ggggcaagaa ggtcaataac cttgatccct gtttcaagga
    17101 tttcagaaga ggtagacaac tcatcaaaag ttggagcttt tttatgaatt ggctgacgct
    17161 ctgcgtcttc tgtaaaagga gcttccaaat caatggtatc tcccaaaacg ttgaagacac
    17221 gtcccaaagt ttctttacct actggtacag agattggacg acccgtgtcc aatacttcca
    17281 ttccacgagt caacccatct gttgattcca tggcgatagt acgaaccata ccatctccta
    17341 actccaaggc tacttcaagg acgatttttg tttttctttc gtcatttttg tagacgacaa
    17401 gtgcattgtt aatctcagga agtttttccc ctgctgcaaa caaaacgtct acaacgggac
    17461 cgataacctg agcaatttta cctgaactca tctccttctc ctattctata taagatactg
    17521 tcggttccta gctcaactag gtcctaagtt cattttcata cgagctggac tagagcctat
    17581 tctaaggcac tagcacctgc tacgatttct gtaatttctt gtgtaatcgc cgcctgtctg
    17641 gcacggttat actgaattgt caaatcattg atgactttct tagcattatc tgtcgctgtt
    17701 tgcatggctg tcatacccgc agcattctca gctgtcttgg catcgataat ggcaccgtaa
    17761 atcatacttt ctgcaaactg aggcaacaac tgctccagaa tttcttctcg gctggtttcc
    17821 aattcaaaag tcaagctgta ctcttcatcc gcttcatttg gatccaagtc aacaatcgga
    17881 agcatttgtt ccacacgcat ttgactggtt agcgtattga catggtggtt gtagcaaaca
    17941 taaagctcat caaagagttc attttggtac atttcaacag tttttgaaat aatcttacga
    18001 acttgatcaa agctaggttg gtctgccaag ccacgtaatt cataaagtgg ttgaataccg
    18061 cgagccttaa agaaatcagc tcccatccca ccgatacaga tcatttcaaa acctttaccg
    18121 tctgggtggt attcttcttt caactccata acagctttca aaatagagga attataacct
    18181 ccaaccaaac cgcggtctga agtgataacg atatagcctg tcttcttcac agaacggcta
    18241 atcaacatcg gattagttga agcaccagct ccattaccat gaaggatatc tgtcaaaagt
    18301 ttacgcactt tctgagcgta aacttggaag ttgcgagcag cttcttcaga acgacctagc
    18361 ttagcagccg ataccatttg catggcatta gtgatttgac tcgtattttt tgttgaggcg
    18421 atttttgttt taatatcatt tagagatact gccatctgac acctctattc ttattggaag
    18481 ctagattgat tgagaaactc tgtaatcgca gcatccaaga ctgcttcttc tggcaagtct
    18541 tttgtatcac gaatggtttc caaaatctct ggatgttgag catcaaagaa ggtatggaac
    18601 tcttcctcga aacgaacaat atcatctact ggaacagtat ccaagaaacc atgtgtcaaa
    18661 gcataaagaa tggttacttg tttctcaaca ggtaatggtt tgtgaacagg ttgtttcaag
    18721 acctcaacgg tacgacgtcc acggttcaac ttagcctgtg ttgctgcgtc caagtcagaa
    18781 ccaaacttag taaaggcttc caactcacgg tatgaagcaa ggtcgatacg aagtgtacca
    18841 gcaaccttct tcatggcttt gatttgtgca gaaccaccta cacgagatac agatgaaccc
    18901 gcatcgatgg ctggacgaat acctgcattg aagaggccat cgccaaggaa gatttgtcca
    18961 tcagtgatag aaatcacgtt ggttgcgata taggctgaga tatctcctgc ttgtgtctcg
    19021 ataaatggta gggctgtaat tgatccacca ccaagttcat cagaaacttt agctgagcgc
    19081 tcaagcaaac ggctgtggag atagaaaaca tcccctggga aggcttcacg acctggagga
    19141 cgacgaagca agagcgatag ttcacgataa gctaccgctt gttttgatag atcatcgtat
    19201 acaatcaaaa catgcttacc ttgatacata aattcttccg ccatagcaac cccagtataa
    19261 ggagctagga agagcaatgg agatggttgt gaagcagagg ctgtcacaac gattgtgtag
    19321 tccaaggcac cgtactgacg aagtgtttct acttgcgtac gaactgttga ttctttttgt
    19381 ccaatcgcga cgtagataca gatcatatct tgatcttttt ggttcaagat tgtatcaatc
    19441 gcaatggttg ttttccctgt ctgacggtca ccgataatca actcacgttg accacgacca
    19501 atcggtacaa gggcgtcaat agctttcaaa ccagtttgca atggttctga aacagactta
    19561 cgttgcataa caccaggagc tggtgcttct actggacgag ttttatcagt gtggatttct
    19621 ccaagaccgt caactggacg accaagcgga tccacaacac gaccaatcag actttcacct
    19681 acagggactt ccatgatttt ccctgtacgg cggattgtat cgccttcacg gatatctgta
    19741 aagtcaccta ggatgataat accaacgtct gttgactcca agttttgagc cataccataa
    19801 gagccgtttt caaaattcaa caactctcca ctcatgacat tttcaaggcc atgagcacgc
    19861 gcgataccgt ccccgatata ggttacaaca cctgtttcag tcacatcaaa attgggtttg
    19921 aaattttcaa tttgttgctt aattaaagcg ctgatttctt gtgcgttaat tgccaaaaga
    19981 acaccacttt ctatttcaaa ttttctttaa caactttaag ttgttgttta atactcacat
    20041 caattgtctt gtgattggca aaaatgacaa aaccaccaat gagactttca tcgatttgtt
    20101 cttttacact ccttactttc agagacattt ttttctcaat caaagggagc aaacgagtct
    20161 tctgttcatc agttagagga tgagcagacg taatcgtcac ttcaaatcga tttgtttctt
    20221 tttcaagtcg gttcaagcaa tctacaagca catcataaaa aagatttgct ctgtgattgt
    20281 aggccagaac ctggataaag ttttgtaata aaggcgacac agaatcttgg aaaaaagcaa
    20341 ttgttttttc cttatccgac tcgtctactg ccacttgttt taaaaaagaa ggcagacctg
    20401 ttttttcaac aacttgcttg atttgagtca agtctgaaaa gatacggtct tcttctcctt
    20461 tttcaagtac caattggaca aaaggcatgc tgtatttttc aattaccttt actgttttct
    20521 tgtccattaa gcttctccta gctgatcgat atactgatca atgagtgctt tatgggcatg
    20581 actgtcaagg ttttgtgaga tgattttacc agctaagctg atggtcaaat ctgcgacctc
    20641 acccttaaca ctctgtaaag cttctacttt attttgagca atttcttgat tggctttttc
    20701 ttttaagtgt cctgcttcta gtttagcatc tgctaagata ttagccttac tttgctcagc
    20761 tgtttccttt gcattttcaa tgattgtctt agcttcttta cggctaccag ccaattcatc
    20821 ttcgcgtttt tgagccaata cttctgcttt ttgacgggct tcttcagctc tgtcaatatc
    20881 tgaagcaatt ttttcagctc tttcttcgaa aatgcctgta atattagacc atgcaaattt
    20941 tttaatcaag actagcaaaa gaataaaaga gccagtgatt aaaataaaat taccaattaa
    21001 ttcacctact gttacgtgca tcagttactc ctttctattc ctcttcaata ttaatcttat
    21061 tccctaaata cacagatgtc aaaagagtaa aaacataagc ttggatgcag gaaataaaga
    21121 cagaaaatgc agtccaagcc aaattagctc caaaggctac tggataccaa taaatagctt
    21181 ggtgggaaag aagaagtaac aaactcgtca tgacctctcc tgcaaagata ttcccaaaaa
    21241 tccgcaaagc caaagataag aagtttgtaa attcttccaa gatattcatc ggtatgacaa
    21301 aaacaggact cataaaagat tttatacttt ttttaaatcc acgacgacga acgctttcta
    21361 tatgtgtcaa caaaatgaca agaaaagata aggttaagtc atactgtaaa ttagcggttg
    21421 gcgaactcca ccagttagtc ccatcgatcg tttgaagctt tgtcattaag ccaaggttat
    21481 tggcaatcac catgaaaagg aataaacaaa ggaaaaagag tgagtaatct ttcatgtagc
    21541 gcgaaccaat gttaggttct gtaaatccaa taacaaagtc atagacatac tcaagtacat
    21601 tttgctttcc tttgggtttc aaggtcatat tgcggcttgc ccaataaata aagacaaaaa
    21661 taactcccac aatcaacaaa gtcatggcta acatagtcag attgaagata acaggaccaa
    21721 tagagatgat tggattaata ctttcttcca tctaaaatcc tcccttttct tctcgttcca
    21781 tgtatttatt tgataataaa tgagaagaca agagttacaa agaaagttcc ttcaataaag
    21841 gcaacaccta aaaacatcaa actacgaaac tcagaaagca tatctggttg gcgtgctact
    21901 gatttaaaca gtccattcat caataaacct tcaccgacag atacgcccat acaggcaata
    21961 cataagccta aaaatgttaa attcataaca aattctcctt taaaataaaa tttacttact
    22021 tagtgtagtc ctaaaattta aatttgtcaa cttttaaccg ctattggaag cgtttaataa
    22081 aaattatttc cattt
//
LOCUS       DAVBOG010000034        21565 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.034, whole genome shotgun sequence.
ACCESSION   DAVBOG010000034 DAVBOG010000000
VERSION     DAVBOG010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21565)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21565)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21565
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.034"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..1024
                     /locus_tag="VQ865_001449"
                     /pseudo
     CDS             1..1024
                     /locus_tag="VQ865_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ865_001450"
     CDS             complement(1417..3144)
                     /gene="ezrA"
                     /locus_tag="VQ865_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000064817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HET3135776.1"
                     /translation="MSNGQLIYLMVAIAVILVLAYVVAIFLRKRNEGRLEALEERKEE
                     LYNLPVNDEVEAVKNMHLIGQSQVAFREWNQKWVDLSLNSFADIENNLFEAEGYNHSF
                     RFLKASHQIDQIESQITLIEEDIAAIRNALADLEKQESKNSGRVLHALDLFEELQHRV
                     AENSEQYGQALDEIEKQLENIQSEFSQFVTLNSSGDPVEAAVILDNTENHILALSHIV
                     DRVPALVTTLSTELPDQLQDLEAGYRKLIDANYHFVETDIEARFHLLYEAFKKNQENI
                     RQLELDNAEYENGQAQEEINALYDIFTREIAAQKVVENLLATLPTYLQHMKENNTLLG
                     EDIARLNKTYLLPETAASHVRRIQTELESFEAAIVEVTSNQEEPTQAYSVLEENLEDL
                     QTQLKDIEDEQISVSERLTQIEKDDINARQKANVYVNRLHTIKRYMEKRNLPGIPQTF
                     LKLFFTASNNTEDLMVELEQKMINIESVTRVLEIATNDMEALETETYNIVQYATLTEQ
                     LLQYSNRYRSFDERIQEAFNEALDIFEKEFDYHASFDKISQALEVAEPGVTNRFVTSY
                     EKTRETIRF"
     gene            complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ865_001451"
     CDS             complement(3226..5172)
                     /gene="gyrB"
                     /locus_tag="VQ865_001451"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002283665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HET3135777.1"
                     /translation="MTEEIKNLQAQDYDASQIQVLEGLEAVRMRPGMYIGSTSKEGLH
                     HLVWEIVDNSIDEALAGFASHIQVFIEPDDSITVVDDGRGIPVDIQEKTGRPAVETVF
                     TVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVHVHKNGKIHYQEYRRGHVVAD
                     LEIVGDTDKTGTTVHFTPDPKIFTETTIFDFDKLNKRIQELAFLNRGLQISITDKRQG
                     LEQTKHYHYEGGIASYVEYINENKDVIFDTPIYTDGEMDDITVEVAMQYTTGYHENVM
                     SFANNIHTHEGGTHEQGFRTALTRVINDYARKNKLLKDNEDNLTGEDVREGLTAVISV
                     KHPNPQFEGQTKTKLGNSEVVKITNRLFSEAFSDFLMENPQIAKRIVEKGILAAKARV
                     AAKRAREVTRKKSGLEISNLPGKLADCSSNNPAETELFIVEGDSAGGSAKSGRNREFQ
                     AILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGAEFDVSKARYQKLVLMTDAD
                     VDGAHIRTLLLTLIYRYMKPILEAGYVYIAQPPIYGVKVGSEIKEYIQPGADQEIKLQ
                     EALARYSEGRTKPTIQRYKGLGEMDDHQLWETTMDPEHRLMARVSVDDAAEADKIFDM
                     LMGDRVEPRREFIEENAVYSTLDV"
     gene            complement(5187..5750)
                     /locus_tag="VQ865_001452"
     CDS             complement(5187..5750)
                     /locus_tag="VQ865_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3135778.1"
                     /translation="MKYHDYIWDLGGTLLDNYETSTAAFVETLALYGITQDHDSVYQA
                     LKVSTPFAIETFAPNLENFLEKYKENEARELEHPILFEGVSDLLEVISNQGGRHFLVS
                     HRNDQVLEILEKTSIAAYFTEVVTSSSGFKRKPNPESMLYLREKYQISSGLVIGDRPI
                     DIEAGQAAGLDTHLFTSIVNLRQVLDI"
     gene            complement(5835..6389)
                     /locus_tag="VQ865_001453"
     CDS             complement(5835..6389)
                     /locus_tag="VQ865_001453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HET3135779.1"
                     /translation="MVKVAVMLAQGFEEIEALTVVDVLRRANITCDMVGFEEQVTGSH
                     AIQVRADHVFDGDLSDYDMIVLPGGMPGSAHLRDNQTLIQELQSFEQEGKKLAAICAA
                     PIALNQAEILKNKRYTCYDGVQEQILDGHYVKETVVVDGQLTTSRGPSTALAFAYELV
                     EQLGGDAESLRTGMLYQDVFGKNQ"
     gene            complement(6400..7623)
                     /locus_tag="VQ865_001454"
     CDS             complement(6400..7623)
                     /locus_tag="VQ865_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HET3135780.1"
                     /translation="MKRSLDSRVDYSLLLPVFFLLVIGVVAIYIAVSHDYPNNILPIL
                     GQQVAWIALGLVIGFVVMLFNTEFLWKVTPFLYILGLGLMILPIVFYNPSLVASTGAK
                     NWVSINGITLFQPSEFMKISYILMLARVIVQFTKKHKEWRRTVPLDFLLIFWMILFTI
                     PVLVLLALQSDLGTALVFVAIFSGIVLLSGVSWKIIIPVFVTAVTGVAGFLAIFISKD
                     GRAFLHQIGMPTYQINRILAWLNPFEFAQTTTYQQAQGQIAIGSGGLFGQGFNASNLL
                     IPVRESDMIFTVIAEDFGFIGSVLVIALYLMLIYRMLKITLKSNNQFYTYISTGLIMM
                     LLFHIFENIGAVTGLLPLTGIPLPFISQGGSAIISNLIGVGLLLSMSYQTNLAEEKSG
                     KVPFKRKKVVLKQIK"
     gene            complement(7660..10110)
                     /locus_tag="VQ865_001455"
     CDS             complement(7660..10110)
                     /locus_tag="VQ865_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DnaQ family
                     exonuclease/ATP-dependent helicase"
                     /protein_id="HET3135781.1"
                     /translation="MKTIGNRYVVVDLEATSTGSKAKIIQVGIVVIEDGEIVDHYTTD
                     VNPHEPLDAHIKELTGLTDQRLAQAPDFSQVARKIFDLVEDGIFVAHNVQFDANLLAE
                     NLFFEGYELRNPRVDTVELAQVFFPELEKYSLPILCRELGIPLKHAHTALSDAQATAE
                     LLLFLREKMTQLPKGLLERLLEMADALLYESYLVIEETYRNQSILSSPDLVQVQGLYF
                     KKMAASLEPRKLSQDFSKNISLLNLEVREEQESFAKEVGLLLKDEPVSLIQAPTGIGK
                     TYGYLLPALSQSKERQIVLSVPTKILQNQIMEEEGKRLKEVFHTDIHSLKGPQNYLKL
                     DAFYHSLQENDENRLFRRFKMQVLVWLTETETGDLDEIGQLYRYQHFLADLRHDGNLS
                     SQNLFVTEDFWKRSQERAETCKLLVTNHAYLVTRLEDNPEFVSDRLLIIDEVQKILLA
                     LENLLQETYDIQSIIDLIDKALVGEENRVQQRILESIRFECLYLIEQFQSGKSRKNIL
                     DSLDNLHQYFSELEVEGFDELVRYFTAEGDYWLEVTETSQKKIQISSTKSGRTLLSSL
                     LPESCQVLGVSATLEISQRVSLADLLGYPEVKFVKIESRGKQEQEVVMVKDFPLVTET
                     SLEVYAREVAALLVEIQAFQQPILVLFTAKDMLLAVSDLLTVSHLAQYKNGDVHQLKK
                     RFEKGEQQILLGAASFWEGVDFSSHPFVIQVVPRLPFQNPQEPLTKKINQELNQEGKN
                     AFYDYQLPMAIIRLKQALGRSMRREYQRSLTLILDRRIVGKRYGKQIVASLAEEATVK
                     TISRSEVDEAIDRFFNEL"
     gene            complement(10310..11239)
                     /locus_tag="VQ865_001456"
     CDS             complement(10310..11239)
                     /locus_tag="VQ865_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006154193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3135782.1"
                     /translation="MEKIVITATAESIEQVEQLLEAGVDRIYVGEKDFGLRLPTTFSY
                     DQLREIAKLVHDAGKELIVAVNALMHQDMMDRIKPFLDFLEEIKTDYITIGDAGVFYV
                     VNRDGYSFKTIYDASTMVTSSRQINFWGQKAGASEAVLAREIPSAELFKMPEILEIPA
                     EVLVYGASVIHHSKRPLLQNYYNFTHIDDEKTHKRDLFLAEPSDPESHYSIFEDNHGT
                     HIFANNDLDLMIKLTELVEHGFTRWKLEGLYTPGQNFVEIAKLFIQARNLIQEGNFSH
                     DQAFLLDEEVRKLHPKNRFLDTGFYDYDPDMVK"
     gene            11379..11666
                     /locus_tag="VQ865_001457"
     CDS             11379..11666
                     /locus_tag="VQ865_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3270 domain-containing protein"
                     /protein_id="HET3135783.1"
                     /translation="MPVRKLQSYEVDYQEELNQQLPHYQAYTPEAQSDANLKEILFFI
                     NIAVFCICIAIFSFIFLALKLSTALAFAAAIGFSLLVLKVQRSIIKRKRRR"
     gene            complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ865_001458"
     CDS             complement(11700..13034)
                     /gene="ciaH"
                     /locus_tag="VQ865_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000491790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CiaH"
                     /protein_id="HET3135784.1"
                     /translation="MFSKLKKTWYADDFSYFIRNFGVFTLIFSTMTLIILQVMHSSLY
                     TSVDDKLHGLSENPQAVIQLAINRATEEIKDLENARADASKVEIKPNVSSNTEVILFD
                     KDFTQLLSGNRFLGLDKIKLEKKELGHIYQIQVFNSYGQEEIYRVILMETNISSVSTN
                     IKYAAVLINTSQLEQASQKHEQLIVVVMASFWILSLLASLYLARVSVRPLLESMQKQQ
                     SFVENASHELRTPLAVLQNRLETLFRKPEATIMDVSESIASSLEEVRNMRFLTTSLLN
                     LARRDDGIKPELAEVPTSFFNTTFTNYEMIASENNRVFRFENRIHRTIVTDQLLLKQL
                     MTILFDNAVKYTEEDGEIDFLISATDRNLYLLVSDNGIGISTEDKKKIFDRFYRVDKA
                     RTRQKGGFGLGLSLAKQIVDALKGTVTVKDNKPKGTIFEVKIAIQTPSKKKK"
     gene            complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ865_001459"
     CDS             complement(13024..13698)
                     /gene="ciaR"
                     /locus_tag="VQ865_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CiaR"
                     /protein_id="HET3135785.1"
                     /translation="MIKILLVEDDLGLSNSVFDFLDDFADVMQVFDGEEGLYEAESGV
                     YDLILLDLMLPEKNGFQVLKELREKGITTPVLIMTAKESLDDKGHGFELGADDYLTKP
                     FYLEELKMRIQALLKRSGKFNENTLTYGNIVVNLSTNTVKVEDTPVELLGKEFDLLVY
                     FLQNQNVILPKTQIFDRLWGFDSDTTISVVEVYVSKVRKKLKGTTFAENLQTLRSVGY
                     LLKDVQ"
     gene            complement(13807..16353)
                     /locus_tag="VQ865_001460"
     CDS             complement(13807..16353)
                     /locus_tag="VQ865_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001149089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M1 family metallopeptidase"
                     /protein_id="HET3135786.1"
                     /translation="MQAVEHFIKQFVPEHYDLFLDLSRETKTFSGKVTITGQAQSDRI
                     SLHQKDLEITSVEVAGQARPFTVDHDNEALHIELAEAGQVELVLAFSGKITDNMTGIY
                     PSYYTVDGVKKEVLSTQFESHFAREAFPCVDEPEAKATFDLSLRFDQAEGELALSNMP
                     EIDVENRKETGIWKFETTPRMSSYLLAFVAGDLQGVTAKTKNGTLVGVYSTKAHPLSN
                     LDFSLDIAVRSIEFYEDYYGVKYPIPQSLHIALPDFSAGAMENWGLVTYREVYLVVDE
                     NSTFASRQQVALVVAHELAHQWFGNLVTMKWWDDLWLNESFANMMEYVCVDTIEPSWN
                     IFEDFQTGGVPLALERDATDGVQSVHVEVKHPDEINTLFDGAIVYAKGSRLMHMLRRW
                     LGDADFAKGLHAYFEKHQYSNTIGSDLWDALGQASGRDVAAFMDSWLEQPGYPVLTVK
                     VENDVLKISQKQFFIGENEDKNRLWVVPLNSNWKGLPDTLETESIEIPGYAALLAENE
                     GALRLNTENTAHYITDYQGDLLEAVLAELETLDNTSKLQIVQERRLLAEAGHISYADL
                     LPVLDKLAKEESYLVVSAVSQVISALERFIDEGTDAETAFKGLVAKLARHNYDRLGFE
                     AKDGESDEDELVRQLAVSMMIRSNDAEASQVASQIFATHKENLAGLPAAIRSQVLINE
                     MKHHETKDLLALYLDTYTHATDAVFKRQLAAALAYSTDADNIQNLITSWKDKFVVKPQ
                     DLSAWYYQFLAHQATQKTAWSWARENWAWIKAALGGDMSFDSFVILPAHVFKTQQRLA
                     EYKEFFEPQLSDLALSRNIGMGIKEIAARVDLISREKAAVEAVVLQYGNA"
     gene            complement(16476..16916)
                     /locus_tag="VQ865_001461"
     CDS             complement(16476..16916)
                     /locus_tag="VQ865_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HET3135787.1"
                     /translation="MTPQEMWNKYKQINPLIGDEIDAWAFGVEPDLLADLVFKGEKTA
                     TASAYDLYVLEDEPLPQVGTFDVILDSQNQAVCIVEITKVSVELFNQVSAQHAFKEGE
                     GDKSLAYWRQVHEDFFTDCLGEVGLTFTPESKVVLEEFRKVYPL"
     gene            complement(16891..17760)
                     /locus_tag="VQ865_001462"
     CDS             complement(16891..17760)
                     /locus_tag="VQ865_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PEP-utilizing enzyme, TIM barrel domain protein"
                     /protein_id="HET3135788.1"
                     /translation="MRNQLALSGEKILEKIYPQLFHHVGMIRGEYLLRELNQNIILAS
                     CQQFVKDYLETICSLYSDEEVWYRFTELTNTEANCLVGTKEFFDEGHPLFGYRGTRRL
                     LACLDEFQAEAHVVTEVYQTNPNLSVIFPFVNDADQLKQAITVLRQYGFTGKVGTMIE
                     LPSAYFDLSSILETGISKIVVGMNDLTSFVFATMRNSQWHDMESPIMLDMLRDMQDKA
                     RKNKINFAVAGYLNTSFIQKMNQLGIKCIIHYSSIPEIFDLEIDHPDHLKHIKEESKK
                     LQRSTHDTARNVE"
     gene            complement(17738..18238)
                     /locus_tag="VQ865_001463"
     CDS             complement(17738..18238)
                     /locus_tag="VQ865_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3135789.1"
                     /translation="MEIKKHFGVYAVCLENGKLLCIEKTRGPYQHRYDLPGGSQQLGE
                     GLTETLTREVMEETGFTVRSYSNPRIYDVFVREELKNFMVHHVMALYDVEMNESAPQV
                     TISEAVSDGANDSLGYIWMDIQEITEENASPLVFKVKSELLGFPELDKTSYMNWKVND
                     EKSTCP"
     gene            complement(18249..18947)
                     /locus_tag="VQ865_001464"
     CDS             complement(18249..18947)
                     /locus_tag="VQ865_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006151199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HET3135790.1"
                     /translation="MTKRVLITGVSSGIGLAQARLFLEKGYQVYGVDQGEKPLLEGDF
                     HFLQRDLTLDLEPIFDWCPQVDVLCNTAGVLDDYKPLLEQTAQDIQEIFEINYIIPVE
                     LTRYYLTQMLENKKGIIINMCSIASSLAGGGGHAYTSSKHALAGFTKQLALDYAEAGI
                     QVFGIAPGAVKTAMTAADFEPGGLADWVASETPIKRWIEPEEIAELSLFLASGKASAM
                     QGQILTIDGGWSLK"
     gene            complement(18940..19176)
                     /locus_tag="VQ865_001465"
     CDS             complement(18940..19176)
                     /locus_tag="VQ865_001465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006596738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HET3135791.1"
                     /translation="MTFEEILPGLKAKKKYVRTGWGGAENYVQLFDTIEQNGLALEVT
                     PYFLINVSGEGEGFSMWSPTACDVLATDWVEVHD"
     gene            complement(19276..20202)
                     /locus_tag="VQ865_001466"
     CDS             complement(19276..20202)
                     /locus_tag="VQ865_001466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HET3135792.1"
                     /translation="MRYITLGQDDKELSEIVLGMMRIKDKSVKEVEELVETALSVGIN
                     AFDLADIYGRGRCEELLGLVLKNRPDLREKMWIQSKCGIRIEEFTYFDFSKDYIIKSV
                     DGILQRLKIDHLDSLLLHRPDALMESDQVAEAFDLLYKQGKVRDFGVSNQNPMMMELL
                     KKDVKQPLAVNQLQLSAAFTPGFESAFHVNMEDSQAAMRDGSIFEYCQLHDVVIQAWS
                     VLQFGYFKGNFVGNEKFQALNQVLDRLAIKYGVTSSTIAISWILRYPAKMQAVVGTTN
                     PKHLREVSQAANFSLTRKEWYEIYLAAGNNLP"
     gene            complement(20277..21092)
                     /locus_tag="VQ865_001467"
     CDS             complement(20277..21092)
                     /locus_tag="VQ865_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135793.1"
                     /translation="MKKMKYYEETSALLHEFSEENQKYFEELWESFNLAGFLYDEDYL
                     REQIYLMMLDFSEAERDGMSAEDYLGKNPKKIMKEILKGAPRSSIKESLLTPILVLAV
                     LRYYQLLSDFSKGPLLTVNLLTFLGQLLIFLIGFGLVATILRRSLVQDSPKMKIGTYI
                     VVGTIVLLVVLGYVGMASFIQEGAFYIPAPWDSLSVFTISLVICIWNWKEAVFRPFVS
                     MIIAHLVVGSLLRYYEWMGISNVFLTKVIPLAVLFIGIFVLFRGFKKIKWSEV"
     gene            complement(21096..21416)
                     /locus_tag="VQ865_001468"
     CDS             complement(21096..21416)
                     /locus_tag="VQ865_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000665424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HET3135794.1"
                     /translation="MKETQLLKGVLEGCVLDMIGQKERYGYELVQTLREAGFDTIVPG
                     TIYPLLQKLEKNQWIRGDMRPSPDGPDRKYFSLMKEGEERVSVFWQQWDDLSQKVEGI
                     KNGG"
BASE COUNT         6504 a         4720 c         3807 g         6534 t
ORIGIN      
        1 tcgtcaagaa gaatcaccaa atccctcgta tcatcaacca aaaaattgcg caaaagttaa
       61 ttgaaaagaa ttctatgacc gatattgccc atcagctggc catttcaact tcaactgtca
      121 ttcgaaagct caatgatttt cactttaaac atgatttttc ttgtcttcct gagattatgt
      181 cttgggatga gtatgctttt acaaagggaa agatgagctt cattgcgcaa gattttgaaa
      241 agctcgatat catcactgtt cttgaaggta gaacacaagc tgtcatccga gatcactttc
      301 ttaaatatga tagagccgtc cgatgtcgcg tcaaaatcat tactatggat atgtttagcc
      361 cttactatga cttggctaaa cagcttcgct ttcaaatttc taggctcagg ctgaaacagt
      421 ctcccaggct gtttcactcc cgaatgctaa aatcgttctt gatcgctttc atattgtaca
      481 acatcttagc cgtgctatga gtcgtgtgca tgtccaaatc atgaatcagt ttcatcgaaa
      541 atcccatgaa tacaaggcta tcaagcgcta ctggaaactc attcaacagg atagccgtaa
      601 actgagtgat aagcgatttt atcgtcctac ttttcgtatg cacttaacca ataaagagat
      661 tttaaacaag cttttgagtt attcggaaga cttgaaacac cactatcaac tctatcagct
      721 cttgcttttt catttccaga ataaggaacc agagaaattt ttcggactta ttgaggacaa
      781 tcttaagcag gctcatccta tttttcagac tgtctttaaa accttcctca aagataaaga
      841 aaagattatc aacgcccttc aactacacta ttctaatgcc aaactggaag cgaccaataa
      901 tctcatcaaa cttatcaagc gcaatgcctt tggttttcga aactttgaaa acttcaaaaa
      961 acggattttt atcgctttga atatcaaaaa agaaaggacg aaatttgtcc tttctcaagc
     1021 ttagctgact tcaacccact acagttgaca aagagcccag attaggaact atccgtgagt
     1081 tctctagtct ggagattttt caatagactt cgttattgaa cggttaccaa gttactcaaa
     1141 gtacagattt gaagctgcag ataagactga cgaaatcact ttaatactaa atgaaaatca
     1201 aaaagcaaac taagagcctc aggctgtact tgagtacggt aaggcgacgc tgacgtgatt
     1261 tgaagagatt ttcgaagagt ataaaacact gttttgaggt ggtggataaa tcggctgggc
     1321 aaaaactcaa tctcaggaga aaatgaagta aatctcccca caactataga aaaagatttg
     1381 attctgctcc tcacacaata aaatcttttt cttttattaa aaacgaatcg tttcacgtgt
     1441 tttctcatat gaggtaacaa agcgattggt tacaccaggc tctgccactt ccaatgcttg
     1501 agaaatcttg tcaaatgaag cgtgataatc aaattctttt tcaaaaatat ctaaagcttc
     1561 gttaaatgct tcttgaatgc gttcatcaaa tgagcgatag cggttagaat attgcaagag
     1621 ttgctctgtc aaagttgcat attgtacaat attataagtt tccgtttcta aagcttccat
     1681 atcattcgtt gcaatttcaa gaactcgggt aacagattca atgttaatca ttttttgttc
     1741 taactcaacc attaaatcct cggtattatt gcttgccgta aagaataact tcaagaaagt
     1801 ttgtggaata cctggcagat tgcgtttttc catgtatcgc ttgatagtat ggagacgatt
     1861 gacataaaca ttggcctttt gacgtgcatt aatatcatct ttctcaattt gtgtcaggcg
     1921 ctcactaact gaaatttgct catcttcaat atcttttagt tgagtttgta aatcctcaag
     1981 attttcttca agaactgaat aagcttgggt tggttcttct tgatttgaag ttacctcaac
     2041 aatagctgcc tcaaaactct ctaattctgt ctgaatacga cgaacatggc ttgcagctgt
     2101 ctcaggaagt aaataggtct tgttcaaacg tgcaatatct tctcccaata aagtattatt
     2161 ctctttcata tgttgaaggt aagttggaag agttgcaagt agattttcca ctactttctg
     2221 agcagcaatt tctcgagtaa aaatatcata caaggcattg atttcctctt gtgcctgtcc
     2281 attctcatat tcggcattat ccaattccaa ctgacgaata ttctcttggt ttttcttgaa
     2341 tgcttcataa agcaagtgga aacgcgcttc aatatccgtt tcaacaaaat gataattagc
     2401 atcaattagt ttacgataac cggcttccaa atcctgtaat tgatctggca attctgtaga
     2461 aagcgtagta accaaggctg gaacacgatc cacaatatga cttaaggcca aaatgtgatt
     2521 ttctgtatta tccaaaatca ctgcggcttc cacagggtca cccgatgaat tcaaggttac
     2581 aaattgtgaa aattcagatt ggatattttc taattgtttt tcaatttcat ccaaggcttg
     2641 accatactgt tctgaatttt cagcaactct atgctgaagt tcctcaaata aatccaaagc
     2701 atgaagaaca cgaccactat ttttagattc ttgcttctct aagtctgcca aagcattgcg
     2761 aattgccgca atatcttctt caatcaaagt aatttgactc tcaatttggt caatttgatg
     2821 actggccttg agaaaacgaa atgaatggtt atagccctct gcttcaaaga gattattttc
     2881 aatatcggca aaagagttga gagataaatc gacccatttt tgattccatt cacggaaagc
     2941 cacttgactt tgtccaatca agtgcatatt ttttacagct tctacttcat catttactgg
     3001 aagattgtat agttcttctt ttctttcttc tagtgcctct aatctcccct cgtttcgctt
     3061 acgtagaaag attgccacta cataagccag aactaaaatg actgcaattg caaccattaa
     3121 ataaattagt tgtccattag acatatcaaa ctcctttttt acttgaaaca atcgtaacga
     3181 ttatatcata ttttttagac caagggaact acttctccct attttttaga catcaagtgt
     3241 actatagaca gcattttctt cgataaactc acgacgaggc tctactcgat cccccatcaa
     3301 catatcaaag attttatctg cttctgcagc atcatctaca gaaactctag ccatcaagcg
     3361 atgttcggga tccatggttg tttcccacag ctgatgatcg tccatttcac ctagcccctt
     3421 ataacgctga atagtcggtt tggtacgacc ttcactataa cgggctaaag cttcttggag
     3481 tttgatttct tgatctgcac ccggctggat atattcttta atctcgcttc caaccttgac
     3541 accatagatt ggtggttggg caatataaac ataaccagct tctaggattg gtttcatata
     3601 acgataaatc aaggttaaaa gaagggtacg aatatgggct ccatcgacat cggcatcggt
     3661 catcaaaacg agtttttggt aacgggcttt cgaaacatca aattctgcgc caaatcctgt
     3721 tcccatggct gtgaaaagac tacgaatttc ttcgttagct agaatcttat ccatacttgc
     3781 tttttcaacg ttcaaaatct taccgcgaat tggaaggata gcctgaaact cacggttacg
     3841 accagatttg gctgatccac cagctgagtc tccttcgacg atgaagagtt ctgtttcagc
     3901 agggttatta gaagaacagt ctgctagttt ccctggaagg ttggaaattt ccaaaccaga
     3961 ttttttacgt gtgacttcac gcgcacgctt ggcagccaca cgagccttgg cagccaaaat
     4021 tcctttttct acgatacgtt tggcaatctg tggattttcc atgaggaaat cggagaaggc
     4081 ttcactgaag aggcgattgg taatcttgac cacttcgcta tttcccaatt tggtcttggt
     4141 ttgtccttca aactgtggat ttgggtgttt aactgagata actgcagtta atccttcgcg
     4201 aacatcttcc cctgttaaat tatcttcatt gtctttcagt aacttattct tacgagcata
     4261 atcattgata acacgagtca gtgccgtacg gaaaccttgt tcatgcgttc caccttcatg
     4321 ggtatgaata ttattggcga aactcatgac attttcatgg taacctgttg tgtactgcat
     4381 ggctacctca actgtgatat catccatctc accgtctgta tagattggtg tatcaaagat
     4441 tacatccttg ttctcgttga tatattcaac gtaactagca atcccacctt cataatgata
     4501 atgcttggtt tgttccaaac cttggcgctt atctgtaatt gaaatttgaa gaccgcgatt
     4561 tagaaaggcc aactcttgaa tccgtttatt taatttatca aaatcaaaga ttgttgtttc
     4621 agtgaagatt tttgggtccg gtgtgaagtg aacagttgtt cctgttttat ccgtatctcc
     4681 aactatttca agatctgcga caacatgacc acgacggtat tcttggtaat gaatcttacc
     4741 atttttgtga acatgaacgt ctaattgagt ggaaagggca ttaactactg acgaccccac
     4801 cccgtgaaga ccacctgaaa ccttgtatcc accaccgccg aactttcctc cagcgtgaag
     4861 gactgtaaag acggtctcaa cagcaggacg gcctgttttt tcctgaatat cgactgggat
     4921 accacgccca tcatccacaa cagtaatcga atcatctggc tcaataaaaa cttgaatatg
     4981 gctggcaaat cctgccaagg cctcgtcaat tgagttatca acaatttccc agactagatg
     5041 gtgaagacct tcttttgagg ttgatccaat gtacatccct ggacgcatac gaacagcctc
     5101 taagccctct aaaacttgaa tttgactggc atcataatcc tgtgcctgca gatttttgat
     5161 ttcttctgtc atcttattcc tttttcttat atgtctaata cttgtcttaa attcacgata
     5221 ctggtaaaca agtgggtatc aagtcctgca gcttgacctg cttcgatatc aatcggccga
     5281 tcaccaatga caagaccaga gctaatctga tacttttctc ttaaataaag catggattcg
     5341 ggatttggct ttctcttaaa gcctgagcta gaagtcacca cttctgtaaa ataagctgct
     5401 atagaggttt tttctaaaat ttccaaaacc tgatcatttc gatgagagac caaaaaatga
     5461 cggccacctt gatttgaaat gacttccaat aggtcagaaa ctccttcaaa taaaatcggg
     5521 tgttcaagct ctctggcttc attttccttg tacttttcta aaaaattctc taaattggga
     5581 gcgaatgtct caatcgcaaa aggagtagaa acctttaaag cttgatagac actgtcatgg
     5641 tcttgtgtga taccatacag tgccaatgtt tcaacaaatg cagctgttga agtttcataa
     5701 ttatccagta aagttccacc taaatcccag atgtaatcgt gatatttcat atccttcatt
     5761 atagcatttt tttatgaaaa aagcgatgat ttccctgagt tttccacata aaaaacgaga
     5821 gaataactcc cgttttactg atttttacca aagacatctt gatagagcat tcctgttcgt
     5881 aaactctctg cgtcccctcc tagttgctcc accaactcgt aggcaaaggc aagggctgtt
     5941 gaaggacccc gactggttgt caactgacca tctaccacta ctgtttcctt gacgtagtga
     6001 ccatcaagga tttgctcttg aacgccgtca taacaagtgt atcgcttatt tttcaatatc
     6061 tctgcttgat tgagggcaat tggtgccgca caaatggctg ctagtttctt cccttcttgc
     6121 tcgaagcttt gcaattcttg aatcaaggtc tgattatcac gtaaatgtgc agaaccaggc
     6181 atacctccag gaagaacaat catatcatag tctgataaat ctccatcaaa gacatgatct
     6241 gctcttactt ggattgcatg cgaacccgtt acttgctctt caaaaccaac catatcacat
     6301 gtgatattgg ctcgacgcaa gacatctaca actgtcaagg cttcaatttc ttcaaagccc
     6361 tgagctaaca taactgctac ttttaccatg attttctcct tatttaattt gttttaatac
     6421 aacctttttc cgtttgaatg ggacttttcc gctcttttct tcagctagat tagtctggta
     6481 actcatcgat aaaagcaaac caacaccaat cagattactg ataatagctg atcccccttg
     6541 cgaaataaaa ggcaagggaa tccccgtcaa aggaagtagt ccagtcacag caccgatatt
     6601 ctcaaagatg tggaagagca acatcataat caaacctgtg gaaatataag tgtagaactg
     6661 gttatttgat ttaagagtaa tcttcaacat acggtaaatc aacatgagat agagggcaat
     6721 aaccaggaca gagccaataa agccaaaatc ttctgcaata accgtaaaaa tcatatctga
     6781 ctctcgaact gggataagca gattcgaagc attaaatccc tgaccaaata agccaccact
     6841 cccaatggca atctgtcctt gagcctgctg gtaagtcgtt gtttgggcaa actcaaaggg
     6901 attgagccaa gccaaaatcc gattaatttg gtaggtcggc attccaatct ggtgaagaaa
     6961 agctcgtccg tccttgctaa taaagatagc taagaaacca gcaactcctg ttacagcagt
     7021 cacaaatact gggataataa ttttccaaga aacccctgat aataaaacga ttcctgagaa
     7081 aatggctaca aaaaccaaag ccgtccccaa gtcactttga agtgctaaaa gaactaggac
     7141 tggaatggta aagagaatca tccagaaaat taacaaaaag tccagcggaa ccgtgcgtct
     7201 ccattcctta tgtttctttg taaattggac aatgacacga gccaacatga ggatatagga
     7261 tatcttcata aattctgacg gttggaatag ggtaattcca tttattgata cccagttttt
     7321 ggcacccgtt gatgcaacta agcttggatt ataaaataca atcggcaaga tcataagtcc
     7381 caagcctaaa atatatagaa agggggtcac cttccaaaga aattctgtat taaagagcat
     7441 gaccacaaaa ccaatcacaa gccccaaggc aatccaggcg acctgctgcc ctaaaatggg
     7501 cagaatatta ttgggataat catgactaac ggctatatag atagccacca caccgatgac
     7561 cagtagaaaa aatactggca agagcaaact gtaatcgact cttgagtcga gagaacgttt
     7621 catatatact aaccttatac tttcatacaa tactatttat caaagttcat taaaaaatct
     7681 atcaatagcc tcgtcaactt cggatcgaga gatggtttta acagtcgctt cttctgctag
     7741 agatgctact atttgtttgc cgtatcgttt tccgacgatt ctcctatcca aaataagagt
     7801 taaggaacgt tggtattcac gtctcatact tcttcccaaa gcctgtttta aacgaataat
     7861 ggccattggc aattgataat cataaaaggc atttttccct tcttgattca gttcttgatt
     7921 aatctttttc gtcaagggtt cttgaggatt ttggaaagga agcctcggta caacttgaat
     7981 cacaaaagga tggcttgaaa aatcaactcc ctcccagaaa cttgctgcac caagcaagat
     8041 ttgttgttca cctttttcaa agcgtttctt tagctgatga acatccccat ttttatactg
     8101 ggccaagtgg ctaactgtaa gtaaatccga tactgctaga agcatgtctt tagcggtaaa
     8161 gagaaccaaa atcggttgct ggaaagcttg aatttccact agtaaagcag ctacctctct
     8221 ggcatagact tctaaggagg tttctgttac cagagggaaa tctttgacca taaccacttc
     8281 ttgttcctgt tttccccgag attcaatctt gacaaatttg acttcaggat agcctaaaag
     8341 gtctgccaaa gaaaccctct gactaatctc aagagtagct gatactccca agacttggca
     8401 actctcagga agtaaagagg acagaagagt acggcctgat tttgtagaag aaatctgaat
     8461 tttcttttga ctcgtttcag ttacttcaag ccagtaatca ccttcagctg taaaatagcg
     8521 aaccagctca tcaaagcctt ctacttctaa ttctgaaaaa tactgatgga gattgtccag
     8581 agaatctaag atatttttcc tagatttacc agactgaaat tgttctatca agtagagaca
     8641 ctcaaagcga atactttcta gtatccgttg ttgaaccctg ttttcttctc ctactaaagc
     8701 cttatcaatt aaatcgataa tagattgtat atcgtaggtc tcttgaagca gattttctag
     8761 agctaacaaa atcttttgga cttcatcaat aatcagtaaa cggtcactga caaattcagg
     8821 attatcttca agtctggtta cgagataggc atgattagtc actaaaagct tgcaagtctc
     8881 tgccctttct tgactacgtt tccaaaaatc ttccgtcaca aataagttct gggatgataa
     8941 attcccatca tgacgaaggt ctgctagaaa atgttggtaa cggtagagtt gcccgatttc
     9001 atccaaatct cctgtctctg tctcagtaag ccagaccaag acttgcattt taaagcgtct
     9061 aaataagcga ttttcatcat tttcctgcaa ggaatgataa aaggcatcca acttcagata
     9121 attttgtggt ccctttaagc tatgaatatc tgtatggaac acttccttga ggcgtttacc
     9181 ttcttcttcc atgatttgat tttgaagaat ctttgtcgga acactaagaa caatttgtcg
     9241 ctctttggat tgagataaag cgggtaagag atagccatag gttttcccaa tccctgtcgg
     9301 cgcttgaatc agagagacag gttcatcttt caatagcaag ccaacctctt tagcaaaact
     9361 ttcttgttcc tccctcactt caaggttcaa cagagaaata tttttagaaa agtcttgaga
     9421 tagttttcgt ggctccagag aagctgccat tttcttaaaa tacagacctt gaacttggac
     9481 caagtctgga gaactcagga tagattggtt gcgataagtt tcctcaataa ccaggtagga
     9541 ctcatatagg agagcgtcag ccatttccag caagcgttcc aagagacctt taggaagctg
     9601 ggtcatcttt tcccgtaaaa aaagaagtaa ttctgctgta gcttgggcat ctgaaagggc
     9661 tgtgtgtgcg tgtttaagag gaattcctaa ttctcgacac aaaatcggca agctatattt
     9721 ttccagttca gggaaaaaga cctgggccaa ttcgaccgta tcaacacgag ggtttcttag
     9781 ctcatagcct tcaaaaaata aattttccgc caagagatta gcatcaaact gaacattatg
     9841 ggctacaaaa atcccatcct ccaccaagtc aaatattttt ctggcaactt gcgaaaaatc
     9901 aggtgcttgc gccagacgtt ggtctgtcaa tcctgtcagt tctttgatat gagcatccaa
     9961 gggttcatgt ggattgacat ccgtcgtata gtgatcgacg atttctccat cctcaatcac
    10021 gacaattccc acttggataa ttttagcctt actacctgtg ctagttgcct ctaaatccac
    10081 cacaacatag cgattaccaa tcgttttcat tataaaaaat tataccaaaa aaagggccat
    10141 ttggcaccta caaacatagg ataattttca aactcaagaa cactactttt cttaaaaatc
    10201 ccatcgaata gagcattcta gcctgctgat ttttgtaaaa tagtgaagaa atacgaaaaa
    10261 ttgagagaag aaatgtttgc atcttccttc tctcaacgaa tcatgtattt tatttaacca
    10321 tgtcaggatc gtagtcataa aatcctgtat caaggaaacg gtttttaggg tgaagtttac
    10381 gaacttcttc atccagcaag aaggcttgat catggctaaa gttgccctct tgaatcaagt
    10441 tacgcgcttg gataaagagt tttgcaatct caacaaagtt ctgaccagga gtgtagagcc
    10501 cttctagttt ccagcgagta aagccatgct ccaccaattc tgttaatttg atcatcaaat
    10561 caaggtcatt gttggcaaag atatgggtcc catgattatc ttcaaaaatg gaatagtggc
    10621 tctctggatc acttggctca gccaagaaga ggtcacgttt atgcgtcttt tcatcatcga
    10681 tatgtgtaaa gttatagtag ttttgcaaga gtggacgttt agaatgatgg atgacgctag
    10741 caccgtaaac caaaacttca gcaggaattt ccaaaatctc tggcattttg aaaagttcag
    10801 ctgatggaat ttcacgcgcc aaaacagcct cagatgcgcc agccttttgt ccccagaagt
    10861 taatctgacg actgctagtt accatggttg aagcatcgta gatggtctta aatgaataac
    10921 catcgcggtt aactacgtaa aagacgcctg catccccaat cgtaatatag tctgtcttga
    10981 tttcttccaa gaagtctaag aaaggcttga tacggtccat catatcttgg tgcatgagag
    11041 cattgaccgc aacgatcaat tccttaccag catcatgaac caacttagcg atttcacgta
    11101 attggtcata actaaaggtc gttggcagac gaaggccaaa atctttctca ccgacataga
    11161 tacggtctac gccagcttcg agtagttgtt caacttgttc aatactttca gcagttgctg
    11221 taatgacaat cttttccata agaaaaatta taccacattt ctccaaaatc atccatgctt
    11281 tgaaaatgaa aagggacttt attctttttg taacctttct gtaataattc tctgccgaaa
    11341 aaatgataaa ataggtatgt actgttaagg agagaattat gcccgtaaga aaattacaat
    11401 cctatgaggt agactatcaa gaagaattaa accagcagct tcctcattac caagcttata
    11461 cacctgaagc gcaatctgat gccaatctca aggaaatcct attttttatt aatatcgctg
    11521 ttttttgtat ctgtattgct atctttagtt ttatcttttt agcattaaaa ttatcaactg
    11581 ctcttgcctt tgccgcagca atcggattca gcttacttgt tttaaaagtt caacggtcta
    11641 ttatcaaacg aaaacgtaga agataaatcc aaaatatcgc cccagttgga gcgatatttt
    11701 tattttttct ttttagatgg tgtctgaatg gcaatcttca cttcaaagat tgttcccttg
    11761 ggtttattat ctttgacagt aacagttcct tttagagcat ctacaatttg cttggctagg
    11821 gataatccta aaccaaaacc acctttttgc cgggttctag ccttgtctac tcgataaaaa
    11881 cggtcaaaaa ttttcttttt atcttctgtc gaaataccga ttccattatc agaaacaagt
    11941 aaataaagat tgcgatcggt cgccgagata agaaaatcaa tttcaccatc ctcctcagta
    12001 tacttgacgg cattatcgaa aagaatggtc atcagttgtt tcagaagaag ctgatctgtg
    12061 acaattgttc gatggatacg attttcaaaa cggaagacac gattattttc cgaagcaatc
    12121 atctcatagt ttgtgaaagt tgtattaaaa aagctagttg gaacttctgc aagctctggc
    12181 ttaatcccat catctctccg agctaagttc agcaagcttg tcgttaaaaa acgcatattt
    12241 cggacttctt ccaaactcga tgcaatgctt tcactcacat ccataatggt agcttctggc
    12301 ttacgaaaaa gggtctctaa gcgattttgc aaaactgcga gtggagttcg taactcatga
    12361 ctggcatttt ccacaaaaga ctgttgcttc tgcatactct caagcagggg cctaacactg
    12421 accctagcta gatagagact ggcaagtaaa gacaaaatcc agaaactagc catcacgacc
    12481 acaatcaatt gctcatgctt ttgactagcc tgctccaact gactggtatt aatcaagaca
    12541 gcagcatact tgatattggt tgaaaccgaa ctaatattgg tctccatcaa aatcacacga
    12601 tagatttctt cctgcccata gctattaaaa acctgaatct ggtagatatg tcctagttct
    12661 ttcttttcta acttaatctt atccaagccc aaaaatcgat ttccagaaag aagttgagta
    12721 aagtccttat caaagagaat gacttccgta ttggaactga cattaggttt tatttctact
    12781 ttactagcgt ccgccctagc attttctaaa tctttaatct cttctgttgc cctatttata
    12841 gccagctgaa taactgcttg aggattttca ctcagtccat gaagcttatc gtccaccgaa
    12901 gtataaagac tcgaatgcat gacttgtaaa ataatcagag tcattgtaga aaaaatcagg
    12961 gtgaagacac cgaagttgcg gataaaataa ctaaagtcat ccgcatacca tgttttttta
    13021 agtttactga acatctttta aaagataccc aacactacgc aaggtttgca aattctctgc
    13081 aaaagtggtt ccctttaatt tcttacggac ttttgaaaca tagacttcga caaccgaaat
    13141 cgttgtatca ctatcaaatc cccatagacg gtcaaaaatc tgcgtcttag gcaaaatcac
    13201 attttgattt tgaaggaaat aaactagtaa atcgaactct ttccccagca attcgacagg
    13261 agtatcttca actttaacgg tattggttga taaattaacc acgatattcc cataagtcaa
    13321 ggtgttttca ttaaacttcc ctgaacgttt gagaagggcc tgaatccgca ttttaagttc
    13381 ttctaggtag aaaggtttgg tcagataatc atccgctccc agttcaaatc catgtccctt
    13441 gtcatccaaa ctttccttgg cagtcataat cagaactggt gtcgtaattc ccttttcacg
    13501 caattctttt aagacttgga aaccattttt ttctggcaac atcaaatcca gcaaaatcaa
    13561 gtcatagaca ccactctcag cttcgtagag accttcttct ccatcaaata cctgcataac
    13621 atccgcaaaa tcgtctaaaa agtcaaatac tgaatttgac agacctaggt catcctcaac
    13681 caataagatt tttatcatga gaaactcctc cttattaaaa ctattatacc aaatttgcct
    13741 taaaaaaaac tcaactctct gcattttaca tgagatagct gagttttctt tttattttag
    13801 gcttatttat gcatttccgt attgaagaac aactgcttcg actgcagctt tttcacggct
    13861 aatcaagtca acacgtgctg caatttcctt gattcccata ccgatgttac ggctaagagc
    13921 aaggtcagaa agttgcggct caaagaactc cttgtattcc gccaagcgtt gctgagtctt
    13981 aaatacatga gcaggaagga taacaaagct atcaaagctc atatctcctc caagggctgc
    14041 cttaatccaa gcccagtttt cacgcgccca agaccaagct gttttctgag ttgcttgatg
    14101 agctaggaat tggtaatacc aagcagacaa gtcctgtggt ttgaccacaa atttgtcctt
    14161 ccaagaagta atcaagtttt ggatattatc cgcatctgta ctgtatgcaa gagctgctgc
    14221 caactggcgt ttaaagacag catctgttgc gtgagtataa gtatcaagat aaagtgctaa
    14281 caagtcttta gtctcatgat gtttcatctc attaatcaga acttgtgaac gaatagctgc
    14341 tgggagtcct gcaagattct ccttgtgtgt tgcgaagatt tggctagcga cttgactagc
    14401 ttctgcatca tttgagcgaa tcatcatcga aacagccagc tgacgaacca attcatcctc
    14461 atctgattct ccgtctttag cttcaaaacc aagacggtca tagttatgac gagccaattt
    14521 agcaaccagt cctttgaagg ctgtttcagc atccgttcct tcatcaataa agcgctcaag
    14581 agctgaaatc acttgagaaa cagctgaaac caccagataa gactcttcct tagcaagttt
    14641 atcaagaact ggaagcaagt ctgcataaga aatgtgccct gcctcagcca acaaacgacg
    14701 ttcttgaaca atttgcagtt tgcttgtgtt atcaagtgtc tctagctcag caagaacagc
    14761 ttctaacaag tctccttgat agtcggtaat atagtgggca gtattttcag tgttgagacg
    14821 aagagctcct tcattttcag caagaagagc tgcgtagcca gggatttcga tactttcagt
    14881 ttcgagtgta tcaggcaagc ctttccagtt gctattgagg ggcaccaccc agagacggtt
    14941 cttgtcttcg ttctcaccga tgaagaattg tttttgtgaa atcttcaaga catcattttc
    15001 aactttgaca gtaagaactg ggtaaccagg ctgttccaac caagaatcca tgaaggctgc
    15061 gacatcacgt cctgacgctt gaccaagggc atcccaaagg tcactaccaa tggtgttgct
    15121 gtattggtgt ttttcaaagt aggcgtgcaa acctttagca aaatcagcat ctcctagcca
    15181 acggcgaagc atgtgcatga gacggcttcc tttggcatag acgatagcgc cgtcaaagag
    15241 tgtattgatt tcatctggat gtttaacttc gacgtggaca gactgaacgc catcagtagc
    15301 gtcacgttca agagcaagag gtactccacc tgtttggaaa tcttcaaaga tattccagct
    15361 tggttcgatg gtatccacac agacgtattc catcatatta gcgaaacttt cattgagcca
    15421 aaggtcatcc caccatttca tagtcacgag gttcccaaac cattggtgag ccaattcatg
    15481 agccacaaca agggcaactt gttgacggct agcaaatgta gagttttcat cgacaaccaa
    15541 gtaaacttca cggtaggtca caagacccca gttttccata gcaccagctg agaagtcagg
    15601 aagggcgatg tggagagatt gaggaattgg gtacttaact ccatagtaat cttcgtaaaa
    15661 ctcgatagag cgaacagcga tatccagtga gaaatcaaga tttgaaagtg gatgtgcttt
    15721 ggttgagtag acacctacca gggtaccatt tttagtttta gcggtcaccc cttgcaaatc
    15781 accagcaaca aaggccaaca agtaagaaga catgcgaggt gttgtctcaa acttccagat
    15841 acctgtttcc ttacggtttt caacatcgat ttctggcatg tttgacaagg ccaattcacc
    15901 ttctgcttgg tcaaagcgaa gagagaggtc aaaagttgct ttggcttcag gctcatccac
    15961 acatgggaaa gcttcgcgcg caaaatggct ctcgaactga gtagacaaga cctccttctt
    16021 gactccatca actgtataat aagaagggta aatccctgtc atgttgtctg taattttacc
    16081 agaaaaggca agaaccaatt caacttgacc agcctcagcc aattcgatat gaagggcttc
    16141 attgtcatgg tcaactgtaa atggacgagc ttgacctgca acttctacag aggtgatttc
    16201 caagtctttt tggtggaggg agatgcggtc actctgtgct tgaccagtga tggtcacttt
    16261 cccagaaaaa gtcttggtct cacgactcaa atctaaaaat aaatcataat gttcaggaac
    16321 aaattgctta ataaaatgtt caactgcttg catagttttc tcctattcta agtttaagag
    16381 ctgctgctct tcttcaaaca aacttattat atcatatttt gcttgagaaa aaaggattgg
    16441 acagcgattt ccaaaacttt cttccttcta atagtctaca gtgggtagac cttgcgaaat
    16501 tcttctaaaa caaccttgct ttcaggtgta aaagtcagcc ctacttcacc caaacagtct
    16561 gtgaaaaagt cctcatgaac ctggcgccaa taggcaagtg atttgtctcc ctcaccttcc
    16621 ttaaaggcat gttgcgcaga aacttgattg aagagttcaa cagaaacctt tgtaatttcg
    16681 acaatgcaga cagcctgatt ttgactatct aaaatgacat cgaaggtccc tacttgggga
    16741 agtggttcgt cttctagtac atagaggtca taggctgatg ctgttgctgt cttttctcct
    16801 ttaaacacca aatccgctaa aaggtctggt tcaactccaa aagcccaagc atcgatttca
    16861 tctccgatca aaggattgat ttgcttgtat ttattccaca tttcttgcgg tgtcatgggt
    16921 actcctttgt aattttttac tttcttcttt tatgtgttta agatgatctg gatggtcaat
    16981 ctctaaatca aaaatctctg gaatagaact gtagtggata atgcacttga tacccaactg
    17041 attcattttt tgtatgaaag aagtattcag atagcctgct acagcaaaat taatcttgtt
    17101 ctttcttgct ttatcctgca tatctcttag catatctaac attattggac tttccatatc
    17161 atgccattga ctgtttctca tagtcgcaaa aacaaaggaa gtcaaatcat tcattccaac
    17221 tacaatcttt gaaatgcccg tttccagtat actagataag tcaaaatacg ctgacggtaa
    17281 ttcaatcatc gttccgactt tcccagtaaa gccatactga cgcaatactg taatagcttg
    17341 ttttaattgg tcggcatcat tgacaaaagg aaagataaca gatagattgg ggttggtttg
    17401 ataaacttct gtaacgacat gtgcttcagc ctgaaattca tccaaacacg ccagtaaacg
    17461 cctagttcct ctatagccaa acaagggatg cccttcgtca aaaaactctt tagtccccac
    17521 taaacaattg gcttctgtat tcgttaattc agtaaaacga taccaaactt cttcatctga
    17581 gtacagggag cagatagtct ctagataatc ttttacaaat tgctgacaac ttgctaatat
    17641 gatgttttga ttaagctctc tcaacaaata ttccccacga atcatgccga cgtggtgaaa
    17701 tagttgagga taaatttttt caagaatttt ttcgccacta agggcaagtt gatttctcat
    17761 cattcacctt ccaattcatg taagaagtct tgtccagttc tggaaatcct aataattcag
    17821 acttaacctt aaagactaat ggcgatgcat tttcttctgt aatctcttga atatccatcc
    17881 aaatatatcc aagtgaatca ttcgcaccat cagacacagc ttccgaaatc gtaacttgag
    17941 gtgcactctc attcatttca acatcataca aggccatgac atggtgaacc ataaaatttt
    18001 ttaactcttc tctgacgaaa acatcgtaga ttcgaggatt agagtagctt ctaacagtaa
    18061 atcccgtctc ttccataact tctctagtca gcgtttccgt cagtccttca ccaagttgct
    18121 gactgcctcc aggtagatca taccgatgtt gataagggcc tctcgttttt tcaatgcaga
    18181 gtaacttccc attttctaag caaacagcgt agactccaaa gtgttttttg atttccatcc
    18241 aactcctcct acttcaaaga ccagccacca tctattgtca agatttgtcc ttgcatggcg
    18301 ctcgcttttc cacttgctaa aaaaagacta agctctgcta tttcctctgg ctcaatccag
    18361 cgcttgattg gggtttcact agccacccag tcagccaaac cacctggttc aaaatccgca
    18421 gcggtcatag ctgtcttgac tgctcctgga gcgataccaa agacctgaat cccagcttca
    18481 gcatagtcta gagccaactg cttggtgaag ccagccaagg catgcttgga tgaagtatag
    18541 gcgtgaccac ctccacctgc taggctagaa gcaatggaac acatattgat gatgattccc
    18601 tttttatttt ccagcatttg tgtcaaataa taccgagtca actctactgg aataatgtag
    18661 ttgatttcaa aaatctcttg aatgtcctgc gccgtttgtt ccaacagtgg tttgtaatca
    18721 tccaaaactc cggcagtatt acacaaaaca tccacctgag ggcaccagtc aaaaataggt
    18781 tccaagtcca aggtcaaatc tctctgtaaa aagtgaaaat caccctctaa gagtggcttt
    18841 tcaccttggt caactccata aacttgatag cccttctcta aaaagaggcg agcttgagcc
    18901 aatccgatcc ctgaactcac tcctgtaatg agtacacgtt tagtcatgca cttctaccca
    18961 atccgttgcc aaaacatcac aagctgtcgg gctccacatg gaaaaacctt ctccttctcc
    19021 agacacgttg attaagaaat aaggtgtcac ttcaagtgca agcccatttt gctcgatggt
    19081 atcaaagagt tggacatagt tttcagcacc tccccaacca gttcgtacat attttttctt
    19141 agcctttaag ccaggtagaa tttcttcaaa tgtcatgttt ttctccttta atgtcaataa
    19201 ttctcccctt cattataaca aaaaaaccgc tttaaaacgg ctttttgact gtgatttatt
    19261 tacatcttct tctacttacg gcaaattatt ccctgcagca agataaattt cataccattc
    19321 ttttcttgtt aagctaaagt ttgccgcttg gctaacttct ctcaagtgct taggatttgt
    19381 ggtacctaca actgcctgca tttttgctgg ataacgcaat atccaagaaa tggcaatagt
    19441 tgaagaggtt actccatatt taatagctaa acgatcaagt acttgattta aagcttgaaa
    19501 tttctcattt ccaacaaaat tccctttaaa atacccgaat tgtaagacag accatgcttg
    19561 aatgaccaca tcgtgtaatt ggcaatattc aaaaatgctg ccatctcgca tagctgcttg
    19621 actatcttcc atattaacat gaaaagctga ttcaaatcct ggagtaaaag ccgcactcaa
    19681 ttgtagctga ttaacagcta acggctgctt gacatctttt ttaagcaact ccatcatcat
    19741 aggattttga ttagaaactc caaaatctcg aactttacct tgtttataaa ggagatcaaa
    19801 ggcttctgct acttggtcag attccatcaa agcatctggt cgatgaagga gcaagctatc
    19861 tagatgatca atcttcaatc tttgcaaaat accgtctact gattttataa tatagtcctt
    19921 agaaaaatca aaataggtaa attcttcaat gcgaatgcca catttggact gaatccacat
    19981 cttttctctt aaatctggac gattttttag gacaagacct aacagttctt cacaacgacc
    20041 acgaccataa atatcagcca agtcgaaggc attgattcca acagaaagtg ctgtttctac
    20101 aagctcttca acttctttta cagacttatc ttttattctc atcattccga gaacaatttc
    20161 tgataattct ttgtcatctt gaccaagagt tatgtatctc atcaaatttt tctcctttaa
    20221 tttctaacat tcttcccttc attataacaa aaaaccgctt tgcaacggct ttttgactat
    20281 acttcactcc attttatctt cttaaaccca cggaacaaga caaagattcc aataaagagg
    20341 acagctaaag gaataacttt tgtaaggaaa acatttgaaa ttcccatcca ctcataataa
    20401 cggagcagag aacccaccac aagatgggca ataatcatac tgacaaatgg acgaaagacc
    20461 gcttctttcc aattccaaat acagataact agcgaaatcg taaagacaga caaactatcc
    20521 cagggagccg gaatataaaa ggctccttct tgtatgaagc ttgccattcc tacatatcct
    20581 aaaacaacta aaagaactat agtcccaaca acaatgtaag tgccaatttt cattttagga
    20641 gaatcttgga ctaaacttct tcgtaaaatt gtggccacaa gtccaaatcc aatcagaaaa
    20701 ataagaagtt gccctaaaaa tgtgagcaaa ttgactgtta agagaggacc tttagaaaaa
    20761 tcacttagta gttgataata acgtaatacc gccaggacaa gaattggcgt caaaagggac
    20821 tctttgatag aactgcgagg tgctcccttg agaatctctt tcattatttt tttaggattc
    20881 ttacctagat aatcctctgc actcatgcca tctcgttctg cttctgagaa atctagcatc
    20941 atcaaataga tctgctctct gagatagtct tcatcataga gaaatccagc aagattaaaa
    21001 ctttcccaca actcctcaaa atacttttga ttctcctcag aaaactcatg tagcaaagcg
    21061 cttgtttctt cgtaatactt cattttcttc atggtttaac ccccattctt aatcccttct
    21121 actttttgac tcaaatcgtc ccattgttgc caaaagactg agacacgctc ttctccttct
    21181 ttcattaatg aaaaatactt ccgatctgga ccatctggcg acgggcgcat gtcgcctctt
    21241 atccattgat ttttttctaa cttttgcaac aaaggataaa tagttcctgg aacgatagta
    21301 tcaaatccag cctctcgcaa agtctgaacc aactcataac cataccgctc tttttgacca
    21361 atcatatcca agacacaacc ttcaagaaca ccttttaata gctgagtttc tttcatcact
    21421 tctcccttct aatctatttt gtaataccta ctagtaactt cacctatagt atatcacttc
    21481 tacactagtt tgtaaagcat aatagttaat actcttcgaa aatctcttca aaccacgtca
    21541 gcgtcgccct accgtatgta tggtt
//
LOCUS       DAVBOG010000035        21353 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.035, whole genome shotgun sequence.
ACCESSION   DAVBOG010000035 DAVBOG010000000
VERSION     DAVBOG010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 21353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21353
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.035"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1343)
                     /locus_tag="VQ865_001469"
     CDS             complement(<1..1343)
                     /locus_tag="VQ865_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RICH domain-containing protein"
                     /protein_id="HET3135795.1"
                     /translation="MFASKSERKVHYSIRKFSIGVASVVVASLVMGSVVHATENEGST
                     QAATFSNMANKSQTEQGEINIERDKAKTAVSEYKEKKVSEIYTKLERDRHKDTVDLVN
                     KLQEIKNEYLNKIVQSTSKTEIQGLITTSRSKLDEAVSKYKKAPSSSSSSGSSTKPEA
                     SDTAKPNKPTELEKKVAEAEKKVEEAKKKAKDQKEEDYRNYPTITYKTLELEIAESDV
                     EVKKAELELVKEEAKEPRNEEKVKQAKAKVESEETEATRLEKIKTDRKKAEEEAKRKA
                     AEEDKVKEKPAEQPKPAPAPQPEKPAPKPENPAPKPENPAPKPEKPAEQQAEEDYARR
                     SEEEYNRLTQQQPPKTEKPAQPSTPKTGWKQENGMWYFYNTDGSMATGWLQNNGSWYY
                     LNSNGAMATGWLQNNGSWYYLNANGSMATGWLQNNGSWYYLNANGSMATGWLQYNG"
     gene            complement(1422..1949)
                     /locus_tag="VQ865_001470"
     CDS             complement(1422..1949)
                     /locus_tag="VQ865_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenylcysteine carboxyl methyltransferase
                     family protein"
                     /protein_id="HET3135796.1"
                     /translation="MVLAIILVTFFIRLIFLKRSIENEKRILSNGGKEFGVENTKRLT
                     MAHIVFYLSCLVEAVVHKTIFDGMGMVGLVLLIFSMLMLMLVIHLLGDIWTVKLMLVN
                     NHKYVDHILFRTVKHPNYFLNILPELIGLTLLSHAYVTFVLVFPVYAVILYRRIAEEE
                     KLLHEVIIPNGSIKR"
     gene            complement(2032..3363)
                     /gene="hk06"
                     /locus_tag="VQ865_001471"
     CDS             complement(2032..3363)
                     /gene="hk06"
                     /locus_tag="VQ865_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000594665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HK06"
                     /protein_id="HET3135797.1"
                     /translation="MIKNPKLLTKSFLRSFAILGGVGLVIHIAIYLTFPFYYIQLEGE
                     KFNESARVFTEYLKTKTSDEIPSLLQSYSKSLTISAHLKRDIVDKRLPLVHDLDIKDG
                     KLSNYIVMLDMSVSTADGKQVTVQFVHGVDIYKEAKNILLLYLPYTFLVTIAFSFVFS
                     YFYTKRLLNPLFYISEVTSKMQDLDDNIRFDESRKDEVGEVGKQINGMYEHLLKVIHE
                     LESRNEQIVKLQNQKVSFVRGASHELKTPLASLRIILENMQHNIGDYKDHPKYIAKSI
                     NKIDQMSHLLEEVLESSKFQEWTECRETLTVKPVLVDILSRYQELAHSIGVTIENQLT
                     DATRVVMSLRALDKVLTNLISNAIKYSDKNGRVIISEQDGYLSIKNTCAPLSDQELEH
                     LFDIFYHSQIVTDKDESSGLGLYIVNNILESYQMDYSFLPYEHGMEFKISL"
     gene            complement(3360..4013)
                     /gene="rr06"
                     /locus_tag="VQ865_001472"
     CDS             complement(3360..4013)
                     /gene="rr06"
                     /locus_tag="VQ865_001472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RR06"
                     /protein_id="HET3135798.1"
                     /translation="MNILVADDEEMIREGIAAFLTEEGYHVIMAKDGQEVLEKFQDLP
                     IHLMVLDLMMPRKSGFEVLKEINQKHDIPVIVLSALGDETTQSQVFDLYADDHVTKPF
                     SLVLLVKRIKALIRRYYVIEDIWRYQDVTVDFTSYKAHYKNEEIDLKPKELLVLKCLI
                     QHKNQVLSREQILEEISKDVADLPCDRVVDVYIRTLRKKLALDCIVTVKNVGYKISL"
     gene            complement(4655..7087)
                     /locus_tag="VQ865_001473"
     CDS             complement(4655..7087)
                     /locus_tag="VQ865_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3135799.1"
                     /translation="MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAG
                     ATLNDYPYELDRLEEVALELTETDYSQDETFTELPFSRRLQILFDEAEYVASVVHAKV
                     LGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA
                     LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQACSGKLEPVIGRDKEISRM
                     IQILSRKTKNNPVLVGDAGVGKTALALGLAQRIASGDVPAEMAKMRVLELDLMNVVAG
                     TRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDSTLDAANILKPALARG
                     TLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQ
                     ITDEAVETAVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKVKYVKADDSDLSPADKAL
                     MDGKWKQAAQLIAKEEEVPVYKDLVTESDILTTLSRLSGIPVQKLTQTDAKKYLNLEA
                     ELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAKALAEVL
                     FDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVE
                     KAHPDIFNVLLQVLDDGVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDI
                     RFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSSDHMQEVVKIMVKPLVASLAE
                     KGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKI
                     GVKAGQLKFDIA"
     gene            complement(7089..7547)
                     /locus_tag="VQ865_001474"
     CDS             complement(7089..7547)
                     /locus_tag="VQ865_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HET3135800.1"
                     /translation="MRFKNTSDHIEAYIKAILDQSGIVELQRSQLADTFQVVPSQINY
                     VIKTRFTESRGYLVESKRGGGGYIRIGRIEFSSHHEMLRELLYSIGERVSQEIYEDIL
                     QLLVEQELMTKQEMNLLESVALDRVLGEEAPVVRANMLRQIIQEVDRKGK"
     gene            complement(7666..8394)
                     /locus_tag="VQ865_001475"
     CDS             complement(7666..8394)
                     /locus_tag="VQ865_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135801.1"
                     /translation="MTEIRLEHVSYAYGQERILEDINLQVTSGEVVSILGPSGVGKTT
                     LFNLIAGILEVQSGRIVLDGEENPKGRVSYMLQKDLLLEHKTVLGNIILPLLIQKVDK
                     AEAISRADKILATFQLTAVRDKYPHELSGGMRQRVALLRTYLFGHKLFLLDEAFSALD
                     EMTKMELHAWYLEIHKQLQLTTLIITHSIEEALNLSDRIYILKNRPGQIVSEIKLDWS
                     EDEDKEVQKIAYKRQILAELGLDK"
     gene            complement(8394..9401)
                     /locus_tag="VQ865_001476"
     CDS             complement(8394..9401)
                     /locus_tag="VQ865_001476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3135802.1"
                     /translation="MKKTWKVFLTLVTALVAVVLVACGQGTASKDNKEAELKKVDFIL
                     DWTPNTNHTGLYVAKEKGYFKEAGVDVDLKLPPEESSSDLVINGKAPFAVYFQDYMAK
                     KLEKGAGITAVAAIVEHNTSGIISRKSDNVSSPKDLVGKKYGTWNDPTELAMLKTLVE
                     SQGGDFEKVEKVPNNDSNSITPIANGVFDTAWIYYGWDGILAKSQGVDANFMYLKDYV
                     KEFDYYSPVIIANNDYLKDNKEEARKVIQAIKKGYQYAMEHPEEAADILIKNAPELKE
                     KRDFVIESQKYLSKEYASDKEKWGQFDAARWNAFYKWDKENGILKEDLTDKGFTNEFV
                     K"
     gene            complement(9439..10197)
                     /locus_tag="VQ865_001477"
     CDS             complement(9439..10197)
                     /locus_tag="VQ865_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009013602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3135803.1"
                     /translation="MRNLKSILRRHISLLGFLGVLSIWQLAGFLKLLPKFILPTPLEI
                     LQPFVRDREFLWHHSWATLRVALLGLILGVLIACLMAVLMDSLTWLNDLIYPMMVVIQ
                     TIPTIAIAPILVLWLGYGILPKIVLIILTTTFPIIVSILDGFRHCDKDMLTLFSLMRA
                     NPWQILWHFKIPVSLPYFYAGLRVSVSYAFITTVVSEWLGGFEGLGVYMIQSKKLFQY
                     DTMFAIIILVSIISLLGMKLVDISEKYVIKWKRT"
     gene            complement(10160..10450)
                     /locus_tag="VQ865_001478"
     CDS             complement(10160..10450)
                     /locus_tag="VQ865_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000647657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-binding protein"
                     /protein_id="HET3135804.1"
                     /translation="MKASIALQVLPLAQGIDRIAVIDQVIAYLQTQEVTMVVTPFETV
                     LEGEFDELMRILKEALEVAVQEADNVFANVKINVGEILSIDEKLEKYTETTH"
     regulatory      complement(10521..10623)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(10706..12052)
                     /gene="cbpD"
                     /locus_tag="VQ865_001479"
     CDS             complement(10706..12052)
                     /gene="cbpD"
                     /locus_tag="VQ865_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000698569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline binding-anchored murein hydrolase CbpD"
                     /protein_id="HET3135805.1"
                     /translation="MKILPFIARGTSYYLKMSVKKLVPFLVVGLMLAAGDSVYAYSRG
                     NGSIARGDDYPAYYKNGSQEIDQWRMYSRQCTSFVAFRLSNVNGFEIPAAYGNANEWG
                     HRARREGYRVDNTPTIGSITWSTAGTYGHVAWVSNVMGDQIEIEEYNYGYTESYNKRV
                     IKANTMTGFIHFKDLDSGSVGNSQSSASTGGTHYFKTKSAIKTEPLVSATVIDYYYPG
                     EKVHYDQILEKDGYKWLSYTAYNGSYRYVQLEAVNKNPLGNSVLSSTGGTHYFKIKSA
                     IKTEPLVSATVIDYYYPGEKVHYDQILEKDGYKWLSYTAYNGSRRYIQLEGVTSSQNY
                     QNQSGNISSYGSNNSSTVGWKKINGSWYHFKSNGSKSTGWLKDGSSWYYLKLSGEMQT
                     GWLKENGSWYYLGSSGAMKTGWYQVSGKWYYSYSSGALAINTTVDGYRVNSDGERV"
     gene            complement(12141..12407)
                     /locus_tag="VQ865_001480"
     CDS             complement(12141..12407)
                     /locus_tag="VQ865_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135806.1"
                     /translation="MSDAFTDVAKMKKIKEEIKAHEGQVVEMTLENGRKRQKNRLGKL
                     IEVYPSLFIVEFGDVEGDKQVNVYVESFTYSDILTEKNLIHYLD"
     gene            complement(12409..13761)
                     /gene="dnaB"
                     /locus_tag="VQ865_001481"
     CDS             complement(12409..13761)
                     /gene="dnaB"
                     /locus_tag="VQ865_001481"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HET3135807.1"
                     /translation="MAEVEELRVQPQDILAEQSVLGAIFIDESKLVFVREYIESRDFF
                     KYAHRLIFQAMVDLSDRGDAIDATTVRTILDNQGDLQNIGGLSYLVEIVNSVPTSANA
                     EYYAKIVAEKAMLRRLIAKLTESVNQAYEASQPADEIIAQAEKGLIDVSENANRSGFK
                     NIRDVLNLNFGNLEARSQQTTDITGIATGYRDLDHMTTGLHEEELIILAARPAVGKTA
                     FALNIAQNIGTKLDKTVAIFSLEMGAESLVDRMLAAEGLVESHSIRTGQLTDEEWQKY
                     TIAQGNLANASIYIDDTPGIRITEIRSRSRKLAQETGNLGLILIDYLQLITGTGRENR
                     QQEVSEISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYERGGEEEEGIPNNKVEVIIEKNRSGARGTVELIFQKEYNKFSSISKREA
                     "
     gene            complement(13805..14257)
                     /gene="rplI"
                     /locus_tag="VQ865_001482"
     CDS             complement(13805..14257)
                     /gene="rplI"
                     /locus_tag="VQ865_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HET3135808.1"
                     /translation="MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATAQAV
                     GELRGKQKSEEKAHAEMIAEGKAIKAQLEAEETVVEFVEKVGPDGRTFGSITNKKIAE
                     ELQKQFGIKIDKRHIQVQAPIRAVGLIDVPVKIYQDITSVINLRVKEG"
     gene            complement(14254..16227)
                     /locus_tag="VQ865_001483"
     CDS             complement(14254..16227)
                     /locus_tag="VQ865_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HET3135809.1"
                     /translation="MKKFYVSPIFPILVGLIAFGVLSTFIIFVNNNLLTVLILFLFVG
                     GYVFLFKKLRVHYTRSDVEQIQYVNHQAEESLTALLEQMPVGVMKLNLSSGEVEWFNP
                     YAELILTKEDGDFDLEAVQTIIKASVGNPSTYAKLGEKRYAVHMDASSGVLYFVDVSR
                     EQAITDELVTSRPVIGIVSVDNYDDLEDATSESDISQINSFVANFISEFSEKYMMFSR
                     RVSMDRFYLFTDYTVLEGLMNDKFSVIDAFREESKQRQLPLTLSMGFSYGDGNHDEIG
                     KVALLNLNLAEVRGGDQVVVKENDETKNPVYFGGGSAASIKRTRTRTRAMMTAISDKI
                     RSVDQVFVVGHKNLDMDALGSAVGMQLFASNVIENSYALYDEEQMSPDIERAVSFIEK
                     EGVTKLLSVKDAMGMVTNRSLLILVDHSKTALTLSKEFYDLFTQTIVIDHHRRDQDFP
                     DNAVITYIESGASSASELVTELIQFQNSKKNRLSRMQASVLMAGMMLDTKNFTSRVTS
                     RTFDVASYLRTRGSDSIAIQEIAATDFEEYREVNELILQGCKLGSDVLIAEAKDTKCY
                     DTVVISKAADAMLAMSGIEASFVLAKNTQGFISISARSRSKLNVQRIMEELGGGGHFN
                     LAAAQIKDVTLSEAGEKLTEIVLNEIKEKEKEE"
     gene            complement(16363..16911)
                     /gene="raiA"
                     /locus_tag="VQ865_001484"
     CDS             complement(16363..16911)
                     /gene="raiA"
                     /locus_tag="VQ865_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000599099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HET3135810.1"
                     /translation="MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINL
                     KVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKN
                     KVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVED
                     QTTNVIYRREDGEIGLLEVKES"
     gene            complement(16991..17653)
                     /locus_tag="VQ865_001485"
     CDS             complement(16991..17653)
                     /locus_tag="VQ865_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HET3135811.1"
                     /translation="MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEEN
                     CPNCMKTELSTKCQDCQLWCKEGVGVSHRAIFTYNQAMKDFFSRYKFDGDFLLRKVFA
                     SFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
                     KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSL
                     VR"
     gene            complement(17650..18948)
                     /locus_tag="VQ865_001486"
     CDS             complement(17650..18948)
                     /locus_tag="VQ865_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3135812.1"
                     /translation="MKVNLDYLGRLFTENELTEEERQLAEKLPAMRKEKGKLFCQRCN
                     STILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQEDFPKQDVLKWRGQLTPFQEKV
                     SEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
                     LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPML
                     YHAVKNSVKENGLRIFLTATSTNELDKKVRLGELKRLNLPRRFHGNPLIIPKPIWLSD
                     FNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLAEILQEQFPNEKIGFVS
                     SVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGG
                     RVGRSMDRPTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL"
     gene            19004..19639
                     /locus_tag="VQ865_001487"
     CDS             19004..19639
                     /locus_tag="VQ865_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HET3135813.1"
                     /translation="MEFRTIKEDGQVQEEIKKSRFICHAKRVYSEEEARDFITAIKKE
                     HYKATHNCSAFIIGERSEIKRTSDDGEPSGTAGVPMLGVLENHNLTNVCVVVTRYFGG
                     IKLGAGGLIRAYAGSVALAVKEIGIIEIKEQAGIAIQMSYAQYQEYSNFLKEHDLMEL
                     DTNFTDQVDTMIYVDKEEKETIKAALVEFFNGKVTLTDQGLREVEVPVNLV"
     gene            19924..20844
                     /gene="cysK"
                     /locus_tag="VQ865_001488"
     CDS             19924..20844
                     /gene="cysK"
                     /locus_tag="VQ865_001488"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HET3135814.1"
                     /translation="MSIYNNITELIGQTPIVKLNNIVPEGAADVYIKLEAFNPGSSVK
                     DRIALSMIEKAEQDGILKLGSTIVEATSGNTGIGLSWVGAAKGYKVVIVMPETMSVER
                     RKIIQAYGAELVLTPGSEGMKGAIAKAQEIAAERDGFLPLQFDNPANPEVHERTTGAE
                     ILAAFGKDGLDAFVAGVGTGGTISGVSHALKSENSNIQVFAVEADESAILSGEKPGPH
                     KIQGISAGFIPDTLDTKAYDGIVRVTSDDALALGREIGGKEGFLVGISSAAAIYGAIE
                     VAKKLGTGKKVLALAPDNGERYLSTALYEL"
     gene            complement(21041..21310)
                     /locus_tag="VQ865_001489"
     CDS             complement(21041..21310)
                     /locus_tag="VQ865_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3135815.1"
                     /translation="MGLPITRKEISNRHIKTSQYYLEPLYNLLRERLLTQPLLHADET
                     SYRVLESDSQLTYYWTFLSGKAEKQGITLYHHVLIDLFISYFNPL"
BASE COUNT         6274 a         4824 c         3539 g         6716 t
ORIGIN      
        1 ccattgtatt ggagccatcc tgtcgccatt gaaccattag cgtttaggta gtaccatgaa
       61 ccattgtttt ggagccatcc tgttgccatt gaaccattag cgtttagata gtaccatgaa
      121 ccattgtttt ggagccatcc tgtcgccata gcgccattgc tgttgaggta gtaccatgag
      181 ccattgtttt ggagccatcc tgtcgccatt gaaccatcag tattgtagaa gtaccacata
      241 ccgttttctt gtttccagcc tgtttttgga gtagatggtt gtgctggttt ttcagttttt
      301 ggcggttgct gttgagtcaa gcgattatat tcttcttctg atctacgagc atagtcttct
      361 tcagcttgtt gttcagctgg tttttctggt tttggagctg gattctctgg ttttggagct
      421 ggattctctg gttttggagc tggtttttct ggttgaggag ccggcgctgg ttttggttgt
      481 tcagctggtt tttctttaac tttatcttct tctgctgctt ttcgtttagc ttcttcttct
      541 gcttttttac gatctgtctt gattttttct aaccttgtag cctcagtttc ttcactctca
      601 actttcgctt ttgcttgctt aactttttcc tcgtttcgag gttccttagc ttcctctttt
      661 actagttcaa gctccgcttt tttaacttcc acatcggact cagcaatttc aagttcaagc
      721 gttttgtaag taatggttgg gtagttacgg taatcttctt ctttttgatc cttggctttc
      781 ttcttagctt cttcaacctt cttctcagct tctgctacct ttttttctag ttctgtcggc
      841 ttgtttggct tcgctgtatc tgaagcttcc ggtttagtgg aagagcctga acttgacgaa
      901 gaagatgggg cctttttata tttagacaca gcttcatcta gttttgatcg acttgttgta
      961 ataagtccct gtatttcggt ttttgaggtt gattgaacta ttttattcaa atactcgttc
     1021 ttaatctctt gcaacttgtt aactagatct acagtatctt tatgtctatc tctctctaat
     1081 tttgtataga tctcactcac ttttttttct ttatattcac tgaccgctgt ctttgcctta
     1141 tctcgttcta tattgatttc tccttgttct gtctgacttt tatttgccat attagaaaaa
     1201 gtggctgctt gggtacttcc ctcgttctct gtcgcatgaa ccacactccc cataacaaga
     1261 ctggcaacta ctacactagc tactccaata ctaaatttac gaattgaata atgtactttt
     1321 ctttcgcttt ttgatgcaaa catgtttatt tccttctata ttttttcttt aaccttacta
     1381 tatcacttca atatgaactg tatataaatc gaattttgta tttatctctt tatgcttcca
     1441 tttgggatta taacttcatg taatagcttt tcctcttcag ctattcgtcg atacaaaata
     1501 actgcataaa ctggaaaaac taaaacaaaa gtcacataag catgactcaa caaggtcaag
     1561 ccaatcaact caggaagaat atttaaaaag taattaggat gttttactgt cctaaacaag
     1621 atatgatcta catatttgtg attattgaca agcataagct tcactgtcca aatatctccc
     1681 aacaagtgaa tcaccaacat caacatcagc atagaaaaaa taagcaagac caaaccaacc
     1741 atacccatgc catcaaaaat tgtcttgtgc accactgcct caaccaagca agagagataa
     1801 aaaacaatat gagccatagt taatcgtttt gtattctcaa ctccaaattc tttcccgcca
     1861 ttgctaagga ttcgtttctc attctctatc gaacgcttta aaaaaatcaa tcgaataaag
     1921 aatgttacta aaataatcgc taataccata ttagtatcct ttcttttatc tatgcaaaga
     1981 ataacacact tatgttaacc ctatatgaac tttaataaaa aactaatctg tctacaagct
     2041 aatcttaaat tccataccgt gttcataagg gagaaaacta tagtccattt gatagctttc
     2101 taaaatatta ttcacaatgt aaagacccaa accggaactt tcatccttat ctgtcacgat
     2161 ttgagaatga tagaatatat caaataaatg ttctagttct tggtcactta gaggcgcaca
     2221 tgtatttttg atagagagat agccatcttg ctcggatatg attacgcgcc catttttatc
     2281 tgaatattta attgcattac taatcaagtt tgtcaaaacc ttatccaatg ccctaagact
     2341 catgacgacc ctggtagcat ctgtcaattg attttcaatt gtaacaccta ttgaatgagc
     2401 taattcttga taacgtgata aaatatctac taaaactggc ttaacagtca aggtctcacg
     2461 acactctgtc cactcttgga atttagaaga ctccagtact tcttctaata agtggctcat
     2521 ctggtcaatc ttatttatac tctttgcaat atattttgga tgatctttgt aatctccaat
     2581 attatgctgc atattctcta ggataattct aagactggct aaaggggttt tcaactcatg
     2641 tgatgctcca cggacaaagg aaaccttttg attttgcaat tttacaattt gctcattacg
     2701 actttccaac tcatgaataa ccttcaacaa gtgctcatac ataccattaa tctgttttcc
     2761 aacttcacca acttcatctt tcctactttc atcaaaacga atattgtcat ccaaatcttg
     2821 cattttacta gtcacttctg aaatgtaaaa aagaggattg agcaagcgtt tagtataaaa
     2881 ataagaaaaa acaaaggaaa aagcaattgt aaccaaaaat gtatatggga gatacaaaag
     2941 caaaatattc tttgcttctt tgtagatatc caccccgtga acaaattgca ctgttacctg
     3001 tttaccatct gctgtactaa cagacatatc taacatcacg atataatttg atagctttcc
     3061 atctttaata tccaagtcat gcacaagagg gagccgctta tctacaatat ctcttttaag
     3121 gtgagcagat atggtcaagg actttgaata agactggagt aagcttggaa tttcatcaga
     3181 tgtcttagtc tttaaatact ccgtaaacac tcttgcgctc tcattaaact tttccccctc
     3241 cagttgaata taataaaaag gaaaggtcaa ataaatagct atatgaatga ctagaccaac
     3301 accacctaga attgcaaaac ttcttaaaaa agacttggtt aataatttag gattttttat
     3361 cataagctaa tcttataccc aacatttttc acagtcacga tacaatctaa agctaatttt
     3421 ttgcgaagag tacgaatata gacatcaacg accctatcac aaggtaaatc agctacatct
     3481 tttgaaattt cttccaatat ctgctctcta cttaaaactt gatttttatg ctgaatcaaa
     3541 cactttagta ccagtaattc ctttggtttg agatcaattt cttcattttt ataatgtgct
     3601 ttgtaagagg taaaatccac tgttacatcc tgatatcgcc aaatatcctc tatgacgtag
     3661 taacgtctga taagcgcctt aatacgcttg acaagcagta ccaaagaaaa aggttttgtc
     3721 acatgatcat cagcatagag atcaaatacc tgtgactgag tagtttcatc tcccagagca
     3781 ctcaagacga tgacaggaat atcgtgcttt tgattgattt cttttaacac ttcaaaacca
     3841 ctcttcctag gcatcattaa atccagtacc atgagatgga tagggagatc ttgaaatttt
     3901 tccaagacct cttgtccatc cttagccata atgacatgat aaccctcttc tgtcagaaat
     3961 gctgcaattc cttctctaat catttcctcg tcatctgcaa ctaaaatgtt catctctctc
     4021 cctttctact accagaactc catacatcta tttcctgtat gctatttgaa aatttcctac
     4081 cagcctatca tctatgataa tggaatggat ttcatttatc cgctactttt tgtcaacaac
     4141 aacgtcaata caagaaaatc attcatcttg cagcttatac tcttcgaaaa tctcttcaaa
     4201 ccacgtcagc tctatctaca atctaaaaac agtgttttga gcaacctgtg gctagctgcc
     4261 tagtttgttc tttgattttc attgaatatt agtttgattt ttcaaatacc agctagaacg
     4321 gatttgacat gcaaaaaaga aacaggtctc ttttgaaaga ataaaaattt cagataagac
     4381 tgctcttttt ctactacaca cgctctaaga caaatacgac ggagggtaat aaacatatga
     4441 attttgtgtt gaatggtgaa aaccacggat cgtttagaag ctataggttt tagtttcata
     4501 ctcttcgaaa atctcttcaa accacgtcag ctctatctgc aacctcaaac cagtgttttg
     4561 agcaacctgc ggctagctgc ctagtttgct ctttgatttt cattgagttt cactccactg
     4621 tgacttatgg tcagatgctg atacttttat tcttttatgc aatatcaaat tttaactggc
     4681 ctgctttgac accaatctta agtgtgctgc ctgccactaa atctccctta agaagaagtt
     4741 ctgccaactt gtcctccact tctgtttgca gggttctgcg aagtgggcga gctcccatct
     4801 ctgggtcata tccttgattt gctaacaatt tcagagctga agcttgtaat ttcaagtcaa
     4861 tgcctttttc agccaaactt gccactaaag gcttgaccat aatcttcacc acttcctgca
     4921 tatggtcact agataggcta tggaagacca ccttctcatc aatacggttg atgaattccg
     4981 gtctataagc ttttttcagt tcttcaaaca tgcgtttttc catattttcc tggtcaaaac
     5041 gaatatcctt agccccaaaa ccaacagtct tatcatcacg aagggcagtc gcacctaggt
     5101 tcgatgtcat aatgataatg gtatttgaaa aatcgacctt gcgtcccttg ctatctgtca
     5161 aaacaccgtc atccagaact tgcaagagaa cattaaagat atctgggtgg gccttctcta
     5221 cctcatcaaa gaggagaacg gaatagggtt tattgcgaac cttctctgtc aactctccac
     5281 cttcttcgta acccacatag cctggaggag ctccatttag acggctggct gcgaatttct
     5341 ccatatactc actcatatca aagcggataa gggctgattc gtcatcaaag agaacttctg
     5401 ccaaagcctt ggccaactcg gtcttaccga cacctgtggg tcctaggaac ataaaggaac
     5461 cgatcggacg cttgtgactg cgaattcctg actgattacg gcgaatcgca cgactaatgc
     5521 ttgaaacagc ttgatcttga ccgatgacac gtttatggag ttctgcttca agatttagat
     5581 acttcttagc atccgtttga gtcagttttt gaactgggat tcctgacaag cgactcaagg
     5641 tggtcaaaat atcagactct gtcaccaagt ctttgtagac aggtacttcc tcttcttttg
     5701 cgattagctg ggctgcctgt ttccacttgc catccatcag ggccttatca gctggactca
     5761 aatctgaatc gtctgctttt acatacttta ccttattttg cactgttgct gctgcttcgt
     5821 ccaagaggtc gatagcagag tctggcaagt gacgactggt taaataacga tgagccatct
     5881 taaccgctgt ttcaaccgct tcatctgtga tttgtacacg gtgatgtttc tcataagtcg
     5941 ccttcaaacc ttgtaaaata gtcatactat ctgccacact tggttcttca atcgtcactt
     6001 tagcgaaacg acgagaaaga gccgcatctt tttcgatatg tttttgatat tcttcctgag
     6061 tggtggcacc aaccgttctc aaagttccac gcgccaaggc tggtttcaag atattggccg
     6121 catccagagt cgaatcaatc ccgctaccag aacccatgat ggtgtggagt tcatcgataa
     6181 agaggatgac ttggccatct tcttcaatat ccttgatgat attattcatg cgttcttcaa
     6241 agtcaccacg gaagcgtgtc cctgcaacga cattcatcaa atcaagttct aacacgcgca
     6301 tcttagccat ttccgcaggc acgtcaccac tagcaatacg ctgagcaaga ccaagcgcca
     6361 gagctgtttt cccgacacca gcatccccaa ccaagacagg gttgttctta gtcttccggc
     6421 tcaagatttg aatcatacgt gagatttcct tgtcccgacc gatgactggt tctaacttgc
     6481 cagaacacgc ttgctctgtc aaatcatgcg tatagtcctc gagaccacca ctaggagtct
     6541 gcggcatgcc catcatattg gccatagaat tttgcttgtc agctactgta cgatggcgtt
     6601 ggcgtaaagc cttgagatct tcacgagtcc agcctgcccg ttcttctaaa tttcgacgaa
     6661 gagcagcaat cttgacctga tctttcttgt cttcataaga aaaaccagcc ctctccaaga
     6721 tacgagtcgc caaggcattg ccatcatgca aaatcgcata gaggacgtgc tctgtcccta
     6781 gcaccttagc atggaccact gacgctacat actctgcttc gtcaaaaaga atctgcaaac
     6841 gacgggagaa cggcaattcc gtaaaagttt catcctggct atagtccgtt tcagtcagtt
     6901 ccaaagccac ctcttctaaa cggtccagct catacggata atcatttaaa gttgcccctg
     6961 ctacactata actgtgatta gacatggcaa tcaacaagtg ccaagactct agataacgag
     7021 ctccaaaatg tccagcaacc atgtaggcac tttcgataca ttcattcaat gcttttgaat
     7081 agttcatctt acttcccttt tctatctacc tcttgtatga tctgacgtag catgtttgct
     7141 cgaacaactg gagcttcttc tcctaaaacg cgatccaaag ctactgattc tagcaaattc
     7201 atctcctgct tggtcatcaa ttcctgctca accaaaagct ggagaatatc ctcataaatt
     7261 tcttgactga ctcgctcacc aatcgagtaa agcagctccc ggagcatttc atgatgacta
     7321 gaaaactcaa ttcgtcctat acgaatgtag cctccaccac cacgcttact ttcaaccaag
     7381 tagcctctac tttccgtaaa gcgtgtcttg atcacgtagt taatctgact aggaacaacc
     7441 tgaaaggtat ctgccaactg actccgttgc aactccacga taccagattg atctaaaatc
     7501 gccttgatgt aggcctcaat atgatccgat gtatttttaa atctcataac aaacccacct
     7561 ctctctttaa accttgacct tgtttgacta ttataccgaa attttctcat ttttaaaaga
     7621 aaaagggcgc tggtaaagga taatcttcac caactcccta tttttctact tatctaagcc
     7681 taattctgcc aagatttgac gtttgtaggc aatcttttgg acttccttgt cctcatcttc
     7741 agaccaatct agtttaattt ctgaaacaat ctgcccaggg cgatttttca agatatagat
     7801 gcggtcgctg agattgaggg cctcctcaat actatgcgtg atgatcaggg ttgttagctg
     7861 caactgcttg tgaatctcaa gataccaagc gtggagttcc atctttgtca tctcatccaa
     7921 ggcgctaaag gcctcatcta agagaaagag cttgtgccca aaaaggtagg tccggagtaa
     7981 ggctacacgc tggcgcatcc caccgctaag ttcatgagga tacttgtctc ttacagctgt
     8041 cagctggaag gtcgcaagaa ttttatccgc tcgggaaata gcttctgcct tatccacctt
     8101 ttgaatcaag aggggcagaa tgatatttcc aagcaccgtc ttgtgctcca agagcagatc
     8161 cttttgcaac atataactca cgcgcccctt gggattttct tcaccatcaa ggacaattct
     8221 ccctgactga acttctaaaa tcccagcgat tagattaaag agggtggtct ttccaacacc
     8281 acttgggcct aggatggaaa ccacttcgcc tgaagtcacc tgtaggttga tatcctctaa
     8341 aatcctctcc tgaccatagg cataactgac gtgctctagt ctaatttctg tcattatttc
     8401 acaaattcgt tggtgaagcc tttgtctgtc aagtcttctt taaggatacc attttcttta
     8461 tcccatttat agaaagcatt ccagcgagct gcgtcaaatt gaccccattt ttccttgtcg
     8521 cttgcgtatt cttttgacaa gtatttttga gattcgatga caaagtcacg tttttccttg
     8581 agttcaggtg cattcttgat gagaatatct gcagcttctt ctggatgttc catggcatat
     8641 tggtagcctt ttttgatggc ttggatgact ttgcgagctt cttctttgtt atctttcaga
     8701 tagtcgttgt ttgcgatgat aactggtgaa tagtagtcaa actccttgac atagtctttc
     8761 aagtacatga agttagcatc tacaccttga gatttagcaa ggataccatc ccaaccgtag
     8821 taaatccaag cagtatcaaa gacgccattg gcaatcggtg tgattgagtt tgagtcgtta
     8881 tttggtactt tttcaacctt ctcaaagtct ccaccttgag attctaccaa ggttttcaac
     8941 atagcaagtt cagttgggtc attccatgtc ccatatttct taccaaccaa gtcttttgga
     9001 ctgcttacat tatcagattt acgagagatg attcctgatg tattgtgttc aacaatagct
     9061 gcaacggcag tgattcctgc tcctttttcc aatttcttag ccatgtagtc ttggaaatac
     9121 actgcaaatg gtgcctttcc gttgataacc aagtcagaag aactttcttc tggtggcaat
     9181 ttcaaatcaa catccactcc agcttctttg aaataacctt tttccttggc aacataaagc
     9241 cctgtgtggt tggtatttgg tgtccagtct aggataaagt caaccttctt aagttctgcc
     9301 tctttgttgt ctttagaagc agttccttga ccacaggcca caagcacaac agctacaaga
     9361 gctgttacaa gcgttaaaaa cactttccat gttttcttca ttttgatttc ctcttttctt
     9421 tttcaaaaac gctctatttt aagtacgttt ccatttaatc acatattttt cactgatatc
     9481 gaccagcttc atacccaaaa gactgataat cgacaccaga ataataatgg caaacatggt
     9541 atcatactga aacagttttt tagactgaat catataaaca ccaagacctt caaaacctcc
     9601 caaccactca gataccacag ttgtgataaa ggcgtaggag acactgaccc tcagacctgc
     9661 ataaaagtaa ggcaggctaa ccgggatttt aaaatgccac aggatttgcc aagggtttgc
     9721 tcgcatcaga ctaaacaaag tcagcatatc cttgtcacaa tgcctaaaac cgtccaaaat
     9781 actaacgatg atgggaaagg ttgttgttaa gataatcaag acaatcttgg gcaaaatccc
     9841 ataacccagc cacaagacca ggataggagc tatggcaatg gtcggaatgg tctgaatgac
     9901 caccatcata gggtaaatca ggtcattgag ccaagtcaaa ctatccatga gcacagccat
     9961 aagacaggca atcaaaactc ccaaaatcag ccccagtaaa gccactctca aggtcgccca
    10021 gctatggtgc cagagaaatt ctctgtcacg aacaaagggc tggagaattt caagaggtgt
    10081 cggcaggata aacttgggga gaagtttaag aaaacctgct aactgccaga ttgacaatac
    10141 tccgagaaag cccaatagac taatgtgtcg tctcagtata cttttcaagt ttctcatcaa
    10201 tacttaaaat ctctcctaca tttattttga cattggcaaa gacattgtct gcctcctgca
    10261 ctgccacttc cagcgcttct tttagaatgc gcataagctc atcaaactcc ccttccaaga
    10321 ccgtttcaaa tggtgtcact accatcgtca cttcttgagt ttgcagataa gcaatgacct
    10381 gatcaataac agctatccga tcaatcccct gtgctagggg taaaacttgc aaggcaatgc
    10441 ttgctttcat aagaacctcc tcttctcgtt ttccttttaa aaaaaagaaa aacctttacc
    10501 atacatggaa aaggtgcaaa attagactaa gtatcgttcc ctccgctggc attacccaga
    10561 tcaggtgcgg tcgaagttta acacttcctc tcagactgta cacagactcc catatattat
    10621 atgtatatat gatagcgcaa aataagaaaa atgtcaagga aactgcttac agaaaagagc
    10681 aggaaatttc tcctactcca attttctata ctcgttctcc atcactgttt actctgtagc
    10741 catccaccgt cgtattaata gctaaggcgc ctgaagagta agaataatac cacttaccag
    10801 agacctggta ccagcctgtt ttcattgccc ctgaactacc cagataatac cacgagccat
    10861 tctcctttaa ccatcctgtc tgcatttcac cagataattt caaataatac cagctagaac
    10921 cgtctttcag ccatcctgtt gatttagaac catttgattt gaaatgatac caactaccat
    10981 ttattttctt ccaaccgaca gttgaactat tattggatcc atagctagag atatttcctg
    11041 attgattctg ataattttgt gaagaagtca ctccctctag ctgtatatag cgacgacttc
    11101 cgttataagc cgtataactc aaccacttat agccgtcttt ttcaagtatc tgatcataat
    11161 gaaccttctc tccaggataa tagtaatcaa tcacagttgc actaactagg ggttcagttt
    11221 taatagcaga cttgatctta aaataatgag ttcctcctgt tgaagaaaga acagaattac
    11281 ctagaggatt tttattcaca gcctccaatt gaacataacg atagcttcca ttataggcag
    11341 tataactcaa ccacttatag ccgtcttttt caagtatctg atcataatga accttctccc
    11401 caggataata gtaatcaatc acagttgcac taactagggg ttcagtttta atagcagact
    11461 tggtcttaaa ataatgagtt ccgcctgttg aagctgagga ttgactattc ccaacactgc
    11521 cactatccaa atctttaaaa tgaataaatc ctgtcatcgt gtttgctttt ataactcgtt
    11581 tattatagga ttctgtataa ccatagttat attcctcaat ctcaatctga tctcccatta
    11641 catttgacac ccaggcaaca tgaccataag ttcctgcagt agaccaagta atggaaccaa
    11701 tcgtcggtgt attatctaca cgataacctt cccgacgagc acgatgtccc cattcattcg
    11761 catttccata agctgccgga atttcaaaac cattgacatt actcaaacga aaggctacaa
    11821 aagaagtaca ctgacgagaa tacatgcgcc actgatcaat ctcctggctc ccatttttat
    11881 aataagcagg ataatcatcc ccacgcgcaa tcgatccatt tcctctggaa taggcataga
    11941 cactatcacc agctgctagc atcaatccta ctactaaaaa aggaacaagc tttttaactg
    12001 acatcttcaa gtaataactt gttcctcttg ctataaacgg taaaattttc attcttcctc
    12061 cttaaaaaat aatataaagc gatgattgcc ttcacctaaa ttattcggag aaaaaagaaa
    12121 aagtgagaaa atttctcact ttagtcaaga taatgaatca aattcttttc tgtaagaata
    12181 tctgagtaag taaaggattc aacgtaaaca ttaacttgtt tatctccttc cacatcccca
    12241 aactccacaa taaataggga tggataaact tcaattagct tacccaatct atttttttgg
    12301 cgcttacgac cattctccaa agtcatttct acgacttgtc cctcatgtgc cttgatttct
    12361 tctttgattt ttttcatctt ggctacatct gtaaatgcat ctgacatctt atgcctccct
    12421 ctttgagata cttgaaaatt tattgtattc tttttggaaa atcaattcca ctgttccacg
    12481 agctccacta cggtttttct cgataataac ttccacctta ttatttggga taccctcctc
    12541 ttcttcacca ccacgttcat agtagtcatc gcgatagaga aaagctacga tatcagcgtc
    12601 ctgctcaata gacccagatt cacgaatatc agacaagacc ggtctcttgt cctgacgttg
    12661 ttctacacca cgagaaagct gactcagagc gattactgga accttcaatt ccttggctag
    12721 tattttcaac tgacgagaaa tttcagaaac ttcttgttga cgattttctc gaccagttcc
    12781 cgtgataagt tgcaaatagt ctatcaaaat caaaccaaga tttccagttt cttgagccaa
    12841 tttacgagaa cgagaacgaa tctctgtaat ccgaatacct ggcgtatcat cgatatagat
    12901 actggcgtta gctagattac cctgagcaat agtatatttt tgccactcct catctgtcaa
    12961 ttgccctgta cggatagaat gtgactccac caagccttct gcagctaaca tacggtctac
    13021 caagctttcc gcacccattt cgagtgaaaa aatagcaacc gttttgtcca acttagtccc
    13081 aatattctga gcgatattca aggcaaatgc tgtcttacca actgctggac gagctgctaa
    13141 gataatcaac tcctcctcat gaagtcctgt tgtcatatga tccaaatcac gataacctgt
    13201 cgcaatacct gtaatatcgg tcgtttgttg cgagcgagct tccagatttc caaagttgag
    13261 attcaacaca tctcgaatgt tcttaaaccc gcttcgattt gcattttcac tgacatcaat
    13321 caaccctttt tctgcctgag caataatttc atcagctggt tgtgacgctt cgtaagcttg
    13381 gttgacagac tctgtcaact tggcaattaa acgacgtagc attgcttttt ctgcaacaat
    13441 cttagcataa tactccgcat tagcagaagt tggcacagaa ttaacaatct caaccaagta
    13501 agacaagcca ccaatattct gtaaatcacc ttgattatca aggatagtac gaaccgttgt
    13561 tgcatctatg gcatcaccac gatcggataa atcgaccatg gcttggaaaa tcaaacgatg
    13621 ggcatactta aaaaagtccc gagactcaat gtattctcgc acaaaaacaa gtttactctc
    13681 atcaataaag atagccccta aaacggattg ctcagctaag atatcttgag gttgtactcg
    13741 taactcttct acttctgcca tcagacttcc cttcctttta caatcttgtc aagaaggtgt
    13801 aaacttatcc ttctttcaca cgaagattga ttacacttgt gatatcttga tagattttca
    13861 ctggcacatc aatcaaacca accgctcgaa tcggagcttg tacttgaata tgacgtttat
    13921 caatcttaat tccaaattgc ttttgcaatt cttctgcaat cttcttattg gtaatagaac
    13981 caaaggtacg accatctgga ccaacttttt caacaaattc tacaacagtt tcttctgctt
    14041 caagttgtgc tttaattgct tttccttctg caatcatctc agcgtgagct ttttcttccg
    14101 atttttgttt accacgaagt tcacctacag cttgagcagt cgcttctttg gctagattct
    14161 ttttgataag aaagttttgc gcataccctg ttggtacttc cttaatttcg ccttttttac
    14221 cttttccttt aacatctgct aaaaagatta ctttcattct tctttctcct tttcctttat
    14281 ttcatttaat acaatttctg tcagtttttc acctgcttct gacaaggtta catctttaat
    14341 ttgagctgct gccaaattaa agtggcctcc accgcctaac tcttccataa tccgttgtac
    14401 attcagttta ctacgacttc gagctgagat agagataaat ccttgtgtat tcttcgcaag
    14461 aacaaaactc gcttcaatac ctgacatggc taacatggca tctgctgcct tactaataac
    14521 aactgtatca tagcatttcg tgtccttagc ctctgctatt agtacatctg aacctaattt
    14581 acacccctgt aaaataagtt cattaacctc acgatattct tcaaaatctg tcgcagcaat
    14641 ttcctggata gcaatactat cacttccgcg cgttctgaga tagctagcaa catcaaatgt
    14701 ccgactagtt actcgcgagg tgaaattttt agtatccaac atcataccag ccatcaaaac
    14761 acttgcttgc atacgactca aacgattttt cttagaattc tggaactgaa tcaattccgt
    14821 taccaactca ctggcactac ttgcaccact ttcgatataa gtaatgactg cattatctgg
    14881 aaaatcctga tcccttctat ggtggtcaat aacaatggtt tgggtaaata aatcataaaa
    14941 ttcttttgat aatgttaagg ctgtctttga atggtctaca agaatcaaca aagaacgatt
    15001 ggtcaccatc cccattgcat ccttaacaga caacaacttc gtaactcctt ctttttctat
    15061 gaatgaaaca gctcgttcaa tatctggaga catttgttct tcatcataaa gagcatagct
    15121 attttcaatc acattgctgg cgaacaactg catacctaca gcagagccca aagcatccat
    15181 gtctaaattt ttgtgaccga ctacaaaaac ctgatctaca ctccgaatct tatctgaaat
    15241 agctgtcatc atagcgcgcg tacgagtccg tgtacgcttg attgaagcag cagacccacc
    15301 accaaaataa actggatttt tcgtttcgtc gttttcctta acaaccacct ggtcgccacc
    15361 acgtacttca gccaagttca aattgagcaa agcaactttc cctatctcat catgatttcc
    15421 atcgccataa gaaaatccca tacttaaagt caagggcaac tgtctctgtt tcgactcttc
    15481 tctgaaagca tcaataacag aaaatttatc attcatcaag ccctcaagca ccgtgtagtc
    15541 agtaaataga taaaatcgat ccatacttac ccgacgagaa aacatcatgt atttttctga
    15601 aaactctgat ataaaattag ctacaaaact attgatttga ctaatatctg actcagaagt
    15661 tgcatcctcc aaatcatcat aattatccac agagacaatc ccaatcactg gtcgacttgt
    15721 taccaattca tctgttatgg cttgttccct ggatacatct acaaaataca aaacaccgga
    15781 agaagcatcc atatgaacag cataacgctt ctcaccaagc ttggcataag tagacggatt
    15841 tcctactgaa gccttgataa tcgtttgaac agcttctaaa tcaaaatcac catcttcctt
    15901 ggtcaaaatc aattcagcat agggattaaa ccactcaacc tctccagaag ataaattcaa
    15961 tttcataaca cctacaggca tctgttccaa tagagctgtc aaactttctt ccgcttggtg
    16021 gtttacatac tgtatctgtt ctacatcact ccttgtataa tgcactctca gtttcttaaa
    16081 taaaaaaaca tagcctccta caaaaagaaa caaaattaaa accgtcaaca gattattatt
    16141 aacaaaaata atgaaagtgg ataagactcc aaacgcaatc aatcctacta gaataggaaa
    16201 aattggactt acataaaatt ttttcattca aaacctcttg gcacccatta taccataata
    16261 cccctcaaaa agcgactttt taaaagtgta atcagtaatt ctatcaatta taagaaaaag
    16321 gtagtttaca attcagtaaa cctaccttta cacatattga aattaagatt ctttaacctc
    16381 taacaaacca atttcgccat cctcacgacg ataaatcaca ttggttgtct gatcttcaac
    16441 atccacatag ataaagaaat catgccccaa taaatccatt tgtagaattg cttcttccaa
    16501 atccattggt tttaaatcaa tttgttttga acgaacaact ttagactgga caatatttga
    16561 atcttccacc aaagcatctg taaataattg accagttgct accttatttt tatttttacg
    16621 ctcgattttt gttttatttt tacgaatctg acgttcaatt ttatcagtta caaggtcaat
    16681 tgaaccatac atatcttgag atacatcttc tgcgcggaga gtaatagatc caagcggaat
    16741 cgttacttcc actttagccg ttttttcacg ataaactttt aagttaattc gggcatccaa
    16801 ctcttgttct ggttggaagt acttttcgat cttttcgagt ttagaaacta cataatcacg
    16861 aattgcttct gttacttcta ggttttcacc acggatacta tatttaatca tatgagtacc
    16921 ttctttctaa acatttttgt ttttatgatt ttattataac gctttcattc tatttttgca
    16981 aattttttcc tcatcttaca agggaaaatg tttttacatc cttagcaccg gcttcttcca
    17041 acagtttctt aacacgattt atagttgctc ctgtagtata gatatcatct ataagtagga
    17101 tttttttagg aatagtgact ccacttttaa taaagaaagg aagttctgtc cccaagcgct
    17161 ctgaacgatt tttagaagaa ctggctctct cttctctttt ctctaataaa tctagatact
    17221 caaagcctgc tgcctctacc aagccctcaa cctgattaaa tcctctatta gcatatctat
    17281 caggacttag gggaattaca acaaattgat actctttgta ctttttcaac tcctcactta
    17341 aaaatgaagc gaaaactttt cttaacagga agtctccatc aaacttatac cgactgaaaa
    17401 aatccttcat agcttgattg taagtaaaaa tcgctctatg actgactcca actccttctt
    17461 tacaccaaag ttgacaatct tgacactttg ttgacaactc tgttttcata caatttggac
    17521 agttctcttc cccaattctt tcaaaagtag aatcacagtc tgaacaaaga caagagtcat
    17581 cattcctcag aagtaagaga ctactaaaag ttaaaacagt cttcatagtc tgcccacata
    17641 acaagcactt catagaccag cctccttatt catcatctga atttccttaa tcgccttctt
    17701 gattgaagca tttaacccat catggaagaa aagcaaatct cctgtcggtc tatccatgct
    17761 tcgtccaact cgtccaccaa tctgaatcaa actagacttg gtaaacaaac gatgattggc
    17821 ctctactacg aaaacatcca cacaagggaa ggtaactcca cgctccaaga ttgtcgtact
    17881 gataagtatt gtcagttctc catctcgaaa agcttgtact tgctctaatc gatcctctgt
    17941 tacagaagat acaaagccaa ttttctcatt tggaaattgc tcctgtaaga tttctgctaa
    18001 ctgctcccct ttcttaattt ctgaagcaaa aatgagtaac ggataagctg tctttctctg
    18061 cttctcaata taggacttta actttggtga caaacgattc ttgtctaagt agcgattaaa
    18121 atccgataac caaattggtt ttggaataat caacggattt ccatgaaacc gtctcggtaa
    18181 attcagtctt tttagttctc ctaaacggac ctttttatct aactcattgg tcgaagtcgc
    18241 tgttaaaaag attctcaatc cattctcctt tacactattc ttgacagcgt ggtaaagcat
    18301 gggattatca acataaggaa aagcatctac ttcatccact atcagcaaat caaaagcttg
    18361 ataaaacttc aataactgat gggttgttgc aacaactagt ggtgttcgaa aataaggttc
    18421 cgattctcca tgtagcaaag ctattccgca agaaaaatcc tgttgcaggc gcttgtacag
    18481 ctccaaacaa acatctatgc gaggactagc caaacacact gcaccacccg cattgatcac
    18541 tttagccact acttgataaa tcatttctgt ctttccagct cctgttaccg catgaactaa
    18601 ggttggcttt tgcttgtcta ctgcttgaag cagtccctct gacaccttct cttgaaaagg
    18661 agttaattgg ccgcgccatt tgagaacatc ttgcttcgga aaatcctcct gcggaaaata
    18721 gtataaagtt tgatcacttc tgactcgctt catcagcaag cactctcgac aatagtaagc
    18781 accgatgggc aaataccatt cttctagaat agtactatta caacgttgac agaaaagttt
    18841 ccccttctcc tttctcattg ctggaagttt ctccgccaac tgacgttctt cttctgttaa
    18901 ttcattctca gtaaataaac gaccgagata atctaaattt actttcatac ttctttattc
    18961 gtaaaaacta gcactttaga tgatttttta gtacaattaa atcatggaat ttaggacaat
    19021 taaagaggac ggccaagtcc aagaagaaat caaaaaatct cgctttatct gccatgccaa
    19081 gcgtgtttat agcgaagaag aggctcgtga cttcattact gccatcaaaa aagaacacta
    19141 caaagcgaca cataactgct ctgcctttat tattggagaa cgtagtgaaa ttaaacgtac
    19201 aagtgatgat ggtgagccta gtggtactgc tggtgttccc atgcttgggg tactagaaaa
    19261 tcacaatctc accaatgtct gtgtggtcgt gacacgctac tttggtggta ttaaactagg
    19321 cgctggagga ctaattcgtg cttacgccgg cagtgtcgcc ttagctgtca aagaaattgg
    19381 tattattgaa ataaaagaac aggctggcat tgctattcaa atgtcttatg ctcagtacca
    19441 agagtacagt aacttcctta aagaacatga tctcatggag ctggatacaa actttacaga
    19501 tcaagtcgat acgatgattt atgttgataa agaagaaaaa gaaactatta aagctgcact
    19561 tgtggagttt tttaatggaa aagtcacttt aactgaccaa ggtttacgag aggttgaagt
    19621 tcctgtaaac ttagtgtaaa caatgaataa tacagcgttt cgttgacatt ctcacaacta
    19681 ctttagcgag caaaataaaa agatgcgtac caaaatatac tagaaaatga agcaattcaa
    19741 acgaaacctg atatcgtttt ccttcacacc tatttactag aattaactga acgcaatcac
    19801 ttgaaaatta atgactttga tctatgatat atagaaatcc tatcgcttcg ataggatttc
    19861 tatattttac aaatggtatg gatagcgtta tactaaagat atcttataca aagaggtatt
    19921 catatgtcta tttataacaa cattactgaa ttaatcggtc aaacaccgat tgttaaactt
    19981 aacaacatcg tgccagaagg tgctgcagac gtctatataa agcttgaagc atttaatcct
    20041 ggttcatctg taaaagaccg tattgccctt agcatgattg aaaaagctga acaagatggt
    20101 attctgaaac ttggttctac tattgttgaa gcaacaagtg gaaacaccgg tattggactt
    20161 tcatgggtag gtgctgctaa agggtataaa gtcgtcatcg ttatgcctga aactatgagt
    20221 gtagaacgac gtaaaattat ccaagcttat ggtgctgaac tcgtcctaac tcctggtagc
    20281 gagggaatga aaggtgctat tgctaaggct caagaaatcg ctgctgaacg tgatggtttc
    20341 cttcctcttc aatttgacaa tccagctaat ccagaagtac acgaaagaac aacaggagct
    20401 gagatactag ctgctttcgg taaagatgga ttagatgcct ttgttgctgg agtaggtact
    20461 ggtggaacga tttctggtgt ttctcatgca ctcaaatcag aaaattctaa cattcaagtt
    20521 tttgcagtag aagcagatga atctgctatt ctatctggtg aaaaacctgg tcctcacaaa
    20581 attcaaggta tctcagctgg atttattcct gatacacttg atactaaagc ctatgatggt
    20641 atcgttcgtg taacatcaga tgacgctctt gcactcggac gtgaaattgg tggaaaagaa
    20701 ggcttccttg tagggatttc ctcagctgca gctatctacg gagccatcga ggttgccaaa
    20761 aaattaggta caggtaaaaa agtccttgcc ctagcaccag ataacggtga acgttatctc
    20821 tctacagcac tttatgaatt gtaaccgtcc aataacgaag tctattgaaa aatctccaga
    20881 ctagagaact cacggatagt tcctaatctg gagatttctt atttgcactt ttcttgtaca
    20941 actttagtcc atggtaaata ggcctctaaa acctctttgt ttacgagagt ttccacgttt
    21001 ggaagacatt ctagaagata ggatagatat ttctcactat ttataatgga ttgaaataag
    21061 atatgaacaa atcgattagg acatgatggt aaagcgtaat cccttgtttc tcagctttcc
    21121 cagacaaaaa agtccaatag taagtcagct gactatcact ctctagcacc ctataagaag
    21181 tttcatccgc atgaagtaag ggctgagtca atagtctctc tcgcaagagg ttataaaggg
    21241 gctccaaata gtattgactc gtcttgatat gccgattaga gatttcctta cgtgtgattg
    21301 gtaaacccat cctagcccaa tcttcttctt ggcgataatt gggtaccttc aga
//
LOCUS       DAVBOG010000036        20931 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.036, whole genome shotgun sequence.
ACCESSION   DAVBOG010000036 DAVBOG010000000
VERSION     DAVBOG010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20931)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20931)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20931
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.036"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..177
                     /locus_tag="VQ865_001490"
     CDS             <1..177
                     /locus_tag="VQ865_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000869756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135816.1"
                     /translation="FKRVGIVDGKAVEVTLREPYSRDLLKVVKSIKQRQKLIAYRYKE
                     GKLLFVKKEASDVL"
     gene            167..655
                     /locus_tag="VQ865_001491"
     CDS             167..655
                     /locus_tag="VQ865_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135817.1"
                     /translation="MSSEQQERMAVQYAERSLLFTVKSLLKILEWSRRQALAQDSAYK
                     IGVQKLEELLQSPYAIDTINLKKDFLDKPIDIEKFKAFLEKEEIPLAIAWQGDSLHFY
                     AKDRSILDNHLDHLLEKMVNDPEKLADFTMDKSLDDAIDEAKSQITFRQEGAVKQKEM
                     VR"
     gene            655..2532
                     /locus_tag="VQ865_001492"
                     /pseudo
     CDS             655..2532
                     /locus_tag="VQ865_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002883241.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
     gene            2553..2795
                     /locus_tag="VQ865_001493"
     CDS             2553..2795
                     /locus_tag="VQ865_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135818.1"
                     /translation="MITHFKGFVYGVDASAMFAQAMSLLQKGLIAVGAFLVVVGIVNL
                     ATNIKDGGPGVRNAILEIVGGVMVGAAGAFVTQISI"
     gene            2812..3666
                     /locus_tag="VQ865_001494"
     CDS             2812..3666
                     /locus_tag="VQ865_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbL"
                     /protein_id="HET3135819.1"
                     /translation="MNLSLVSPFVYLASEKISAENLFEGFNVDLQSTVDLIKSLSSYN
                     PTVWTYMSSITKSVMQPLGVAILSVVLILEFSKMAKKIANSGGAMTFEALAPMLISYI
                     MVAVVITNTTVIVEAIIGIASHAIEQVASIVAHGGAKYDTLSGLKGSGFIGRMIVGFF
                     ALLIWLVRIVSAAMVNLLVSIRFIQLYLMIPFAPLTIPTFLSDEWKSIGIGYLKNIMV
                     YAVQGVLIFLIVSLVPLFESAGKIAVSNGAGVLQSLAIMFGSLVQAILLIIALVGSQR
                     TARSILGM"
     gene            3720..4079
                     /locus_tag="VQ865_001495"
     CDS             3720..4079
                     /locus_tag="VQ865_001495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PrgI family protein"
                     /protein_id="HET3135820.1"
                     /translation="MNTRVFKDISKYQHRAWLGFTTRQIIFVLPAFIVTIIVLGLNLF
                     FWQFGDWFVYGFVFAFTIPLMLFGVYKPNDLYFEHYLKYRLHFELTVPLRTITGKKGP
                     EHEKKIKYIKETKNFND"
     gene            4030..6387
                     /locus_tag="VQ865_001496"
     CDS             4030..6387
                     /locus_tag="VQ865_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3135821.1"
                     /translation="MKRKSNTLKKQKTSMTNKKEEVKGKKEEVLPSTANTLSYQALYQ
                     NGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNFQLTIFNKR
                     LNLEKFRQSVLYEEKEDGYDTYRKELNRMMNQNLDSGENNFSAVKLISFGRKDSNPKQ
                     AYRSLSQIGEYFKSGFSEIDARFESLAGEDRVNLLADMLRGEHHLPFSYRDLTRSGQT
                     TRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGMELGDQFIRDLMQGDLELIVSLHA
                     QSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
                     TETGDKLFQTVFLIGIFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLP
                     FGCDFLEGVSRSLLTSNVAVNSPWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPS
                     GLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSVIGRAFGGEMIDIAP
                     DSQTYLNVLDLSDENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQS
                     FKEPSLEEWVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKK
                     LGDELKQIALMVVFDQIWNRVVRNQKLGKKTWIYFDEMQLLLLDKYASDFFFKLWSRV
                     RKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGLSKELEK
                     YLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN"
     gene            6399..9212
                     /locus_tag="VQ865_001497"
     CDS             6399..9212
                     /locus_tag="VQ865_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CHAP domain-containing protein"
                     /protein_id="HET3135822.1"
                     /translation="MKDKRKIIRARKAFRRSLKDEKKFLKKGKKEVRKQKKDSAVLDE
                     KAWKKEIKEKLEEMREASKERVKQANEDYNHILQNSPPSLLNRKELRDRRLPHARKRL
                     KIAKKQFREAKVEAKEERKEGRKERKTNQKFLYGQESKAKSNFFFQGKSLEELKAKKE
                     VKDAKENLKSTKQAYKSKKVSRKAKTFLYVLGREGGELASENEDLEGYRTLQETIRKG
                     KRYSRLSYNLGKASVKTGQATGRFTKKRLTNTKERYHHFKDGKGWKLAKDNPSSFKNR
                     YRKLKKQGLTSVRNIYQKLKAAFSFFTFAAGNPATWIVGGIVFLLLLMMSFFLGFSSA
                     SLIQQDEFELTKAYTHLTWEDAEHTRTNDKGITYYTKVDDVMGYMNFKFHDYELHKPV
                     HLFSSETYKDYLSTLWHDLNDGEDLKSMQDLYETPKYKLSKDDQEEMKELKEEGVYAS
                     MQELDNPFEGKSNEDSLTMTYRYGYYDLDGKPTLQEYILLEAKAHQAIVAPMDGVVSL
                     DGDNVILTNGKGENESRLTLYSIHNGRAIEGTRVLTGDVIGETPDDTGLKVSYQKYKN
                     KKEKLVYVNPQFYFPKVIQLQTTILPAIGQFGGDEFERAKHIYEFLKSQGASPQAIAA
                     ILGNWSVESSINPKRAEGDYLSPPVGATASSWDDETWLAIGGPAIYSGAYPNILHRGL
                     GLGQWTDTADGSTRHTALLNYAHSKNKKWYDLDLQLDFMLHGDSPYYQSWLKDFFKNT
                     GSAANLAQLFLTYWEGNSGDKLLERQTRATEWYYQIEKGFSQTNGGQAKSDPQSLEGV
                     RGDLYDHSVPGGGDGMAYAYGQCTWGVAARMNQLGLKLKGSNGEKISIINTMGNGQDW
                     VATASSLGGETGSTPRAGAIVSFVGGTHGTPAIYGHVAFVEKVYDDGSFLVSETNYGG
                     NPNYTFRKISQADSAISFAYTTK"
     gene            complement(9243..9431)
                     /locus_tag="VQ865_001498"
     CDS             complement(9243..9431)
                     /locus_tag="VQ865_001498"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135823.1"
                     /translation="MVYRVCKPPSQSVYSGVCHRLALTSKIAIGFRSGVRHRLALMSK
                     ITIRLTMSRLLIYTIYST"
     gene            9450..10016
                     /locus_tag="VQ865_001499"
     CDS             9450..10016
                     /locus_tag="VQ865_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135824.1"
                     /translation="MANSRDYRNPNYTEKIKLQRFFTQLQIAASFFKEHFVGKIMYYE
                     TEIESVELHFSPTNFMHLCGVDYQKGAGSFFDDCLNRHVIIDELKIKKDGTTMQKLQV
                     LGSIEELLGKHVHLTGSGRYLYLEFDYALRTRKQILALTLKETSRKIVPQSLLDLKRK
                     TVFPKGQKVISIYSKHLQTSELFYYLKD"
     gene            10168..10578
                     /locus_tag="VQ865_001500"
     CDS             10168..10578
                     /locus_tag="VQ865_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014713375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope biogenesis protein OmpA"
                     /protein_id="HET3135825.1"
                     /translation="MEGIYQRDSDQDGLTDAQELALGTNPLSADSDGDGRSDLVEVEE
                     GTNPLEKDLQDIDQTSITEPSSVFMEMKQKISDMMESHYKEFIQALISIETGIENEQD
                     LEDLYTYYMRTDSISLLSSDLETSPQKVEMEIEL"
     gene            10626..16856
                     /locus_tag="VQ865_001501"
     CDS             10626..16856
                     /locus_tag="VQ865_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3135826.1"
                     /translation="MEVMKLLAMFRGTIPKDREKMDLFLRYQAQHFDEKWQDLVESFL
                     VEEGKIEEIPHVYSFHQDIISFLEASSENNDQDLESYTRNFGQAGLSKLSQLSNFEKN
                     LVLEVATYNLSTRFYIQSEKEKLTPLSELVCHQKQDVNLVNVYRVANNLSDRISRDIE
                     EFLLMVDSKELKKEVLEIHFEEKEGDVLAYLGSELMATLDTVTDLVHHEENYQQLPLT
                     QKLKIITHFDEVKAIREKSKQVAESLSPSSDIEQETEETNSFSNIDKIVEEALREYPI
                     GSQVSYKGQVFQLVSIENAQLNDLVRLELFKDSNQLFEENPILYLNSLEEIEQVLSHV
                     ELEKEDSEIEIDSSSESQEIDLFSYLEEENENEKEKEKDKETETLIVGIEETDVPVQD
                     FVFPDDLEDFYPKTNREKIETNIAAIELVKRLEKEGRQANPEEQELLAKYVGWGGLAN
                     EFFDELNPKYETERLTLKSLVSKSEYSTMKQSSLTAYYTDPMIIRQIWQKLLDDGFEG
                     GRILDPSMGTGNFFAAMPRSIRDKSELYGVELDSVTGAIAKQLHPNTHIEVRGFEEVP
                     YQNNSFDLVLTNVPFGNFRIADKNYDKPYMIHDYFVKHSLDLVRDGGQVSIISSIGTM
                     DKRTDNVLQEIKSNTHFLGGVRLPDTAFKKIAGTRVTTDLLFFQKDQAKNLNEEELVF
                     SGSIPFEEDKRVWINPYFDGKYNTQVLGQYEVRNFNGGTLNVKGVSETLVTEIMKAFE
                     NVEAPKQIDNSLKAPVFIQEEVDNSIPSRICEDLALYSFGYEGNQIYYRDTHGIRKSS
                     KVDEISYYVDEKGEFKAWDSSLSEHKIDRFVQLHLTDEEALDVYKSEEASKRGKYKEL
                     FKKTVFYESPLSDKDISRIKGMVDLRETYQALIEIQRHPDYSRSDFQILLSKLNRDYD
                     RFVSQFGYLNASVNRNLFDSDDKYSLLASLEDEYIDSKDQKVKYKKSLAFEKALVRPE
                     RVITRVSTALDALNSSLSDGRGVDLDYMVSIYPEHSQAAILDELGDQILMDPESYLRG
                     ERKYLSKNQFLSGDILNKIEVVQLLVEENNQEYDWNHALDLLESVRPPRIHLADIEFK
                     IGSRWIPQSVYGKFAFECFTNREFELSSPDVEQVIEVNPVDGQVHLRTSFAYRYPSAK
                     DSSLGVSGSRYDTGRKIFENLLNSNQPTITMTVTEGEKKKTITDLEKTSVLRAKEQHL
                     QELFQEFVSRYPEVQQVIEESYNRLYNRTVSREYDGSHLVIDGLAQNISLRPHQENAI
                     QRIVEEKRALLAHEVGSGKTLTMLGAGFKLKELGMVHKPLYVVPSSLSAQFGQEIMKF
                     FPTKKVFVTTKKDFVKARRKQFVSRIITGDYDAIVIGDSQFEKIPVSKERQMNYIEDK
                     LNELREIKTHSENKYTVKEAEQSISGLEKQLEELQRFNRDSFIDFENLGIDFLFVDEA
                     HHFKNIRPITGLGNVAGITNTTSKKNVDMEMKVRQIQEEHDFKNIVFATGTPVSNSIS
                     ELYTMMNYIQPDILKRYQVDYFDSWVGAFGEIQNSMELAPTGDKYQPKKRFKKFVNLP
                     ELMKIYKETADIQTQDMLDLPVPEAHIIPIESELTENQKLYLEELVMRSDAVKCGTVD
                     PSQDNMLKITGEARKLAIDMRLLDSSYSLADNHKLLQVVDNVERIYREGMGNKATQMI
                     FSDIGTPKKKDNGFDVYSEIKALLVDRGIPSKEIAFVHDANSDEKKNSLSRKVNAGEV
                     RILLASTEKGGTGLNVQSKMKAVHHLDVPWRPSDIQQRNGRIIRQGNENKEVDIYHYI
                     TKGSFDNYLWATQENKLRYIKQIMTSKEPIRAAEDIDEQTMTASDFKALATGNPYLKY
                     KMELENDLTLLENQRRAFQRSKDHYRHTISYCEENMPILEKRLSKYEGDIQQSEISKD
                     QAFSMTVGKQAFDQRAEAGESLHRLIRHNQADSKEFRTLASYRGFDIKMLSLPINQPL
                     PETFSVKIVGENQYSVSLDLYSPLGTIQRLQHTIDHIKEDQVKTQNLLDELKDKWTTA
                     KVEIEKNFPKEEDYQTKKAEYDVLAPLIETETDLDIIDQALRQFHEKGKEKQEQLSFE
                     LD"
     gene            16931..17215
                     /locus_tag="VQ865_001502"
     CDS             16931..17215
                     /locus_tag="VQ865_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004263534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135827.1"
                     /translation="MMEDTYYQLEEALVQGFQTPEEYQAYKELKEHYEEVTGDYSFSK
                     RELTSQLEISLQNHRGVDFEEHEKEEYLDLVQKLEEFDSSLATHYRQLID"
     gene            17229..17525
                     /locus_tag="VQ865_001503"
     CDS             17229..17525
                     /locus_tag="VQ865_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135828.1"
                     /translation="MNDLLLIPVIFLAVGGILILLWRLFLIASRLFLIGFVSFLIFVE
                     VYGIYLFFTEPTLYFDDIRQHGLTSFTAVYLFINLMLVLGFSWRFINSMNKEKM"
     gene            complement(17539..17736)
                     /locus_tag="VQ865_001504"
     CDS             complement(17539..17736)
                     /locus_tag="VQ865_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135829.1"
                     /translation="MNKLKEENLRRALSHIERHKQAINTTNNSEDNDFHKLLLQFSYE
                     VYERIKANKKPYPNLDSDKVF"
     gene            17896..18537
                     /locus_tag="VQ865_001505"
     CDS             17896..18537
                     /locus_tag="VQ865_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000933080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HET3135830.1"
                     /translation="MLNKVKTKALISVGAVAATSFILMMGYTAGQHSTAKQSRKEIEL
                     AAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQPYMTESAYSQELTS
                     QNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSDLKNANQSKTNQTE
                     TRTVKLSYSKLPGKLLVNQVQVWKSGLDDLDKVTPKTLEESSSIPSLPNTTTK"
     gene            18547..19632
                     /locus_tag="VQ865_001506"
     CDS             18547..19632
                     /locus_tag="VQ865_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HET3135831.1"
                     /translation="MEIEECKQISILDVANRLGISFKQVSSRVYEHPEHDSFRIFSTT
                     NTFKWFSRDIQGDVIDFVRLVKGISFKDALAFLSEEPFQKEAVQEKRERPFYYPLKRV
                     EDSNCSLARYYLTKCRGISEEIVQKMIQQGLMAQASWKTNETVELVIVFKSFDHRHKL
                     QAASLQGIYKNPALSRERLKTILKGSHGHIGISFDIGKPNRLVFCESFVDLMSYYELH
                     QQSLTDVRLVSMEGLKRSVVAYQTLRLIAEENQKLEFLDTVIPSKLLPLMNTIRDTTT
                     YFDNHPDLLTLAVDCDDAGKDFSDKLFQAGLPVLLDLPDNESGKEKIDWNDILREKKS
                     DLQLILESAKETLRNQPVRQTSQCLEL"
     gene            19683..19916
                     /locus_tag="VQ865_001507"
     CDS             19683..19916
                     /locus_tag="VQ865_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000152421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135832.1"
                     /translation="MTIIERLEEKVTRQESKVARETEKLAAYKEQLETAMFATFKRRQ
                     SISHMSFEEALDHAFGKERQFDDSEFRKDEMSE"
     gene            19913..20296
                     /locus_tag="VQ865_001508"
     CDS             19913..20296
                     /locus_tag="VQ865_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein"
                     /protein_id="HET3135833.1"
                     /translation="MTKDWNFNQPLESKSENQEDPDKIAALFRNHQGGNDVNYEAAFQ
                     KRKQAPVTESNSSSKPKVTEVRTGKETDITTSYQQHLKRLIADNNSDIESSQKKIEEL
                     HTLIDTKNKDNKKLQSIYDAISELH"
     gene            20334..20606
                     /locus_tag="VQ865_001509"
     CDS             20334..20606
                     /locus_tag="VQ865_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135834.1"
                     /translation="MFTKIFKKNQDNSDIFKKLIHRLSDMSVQDLEKIDRLLDIIFTP
                     EQESEQLKTETTYREETLDDTLKKAKNQLHKEQLEKNLERFRKNSQ"
     gene            20676..>20931
                     /locus_tag="VQ865_001510"
     CDS             20676..>20931
                     /locus_tag="VQ865_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003042293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135835.1"
                     /translation="MIGKNIKSLRKTHDLTQHDFARIVGISRNSLSRYENGTSSVSTE
                     LIDIICQKFNVSYVDIVGEDKMLNPVEDYELTLKIEIVKER"
BASE COUNT         7182 a         3317 c         4299 g         6133 t
ORIGIN      
        1 tttaaacgtg ttggtatcgt tgatgggaag gcagtagaag tcactcttcg agaaccttat
       61 tcgagagatc tactgaaggt tgtcaagtcg attaagcaac gtcagaaatt gatagcttat
      121 cgttataaag aaggaaagct gctatttgtg aagaaggagg catcagatgt cctctgaaca
      181 acaggaacga atggcagttc aatatgcaga gcgtagtctt ttatttactg taaaaagtct
      241 tttaaagatt ctagaatggt ctagacgtca ggctttagca caggattccg cctataagat
      301 aggagtgcag aaattagaag aattgctaca atctccctat gcgattgata cgattaatct
      361 gaaaaaagat tttttagaca aaccaattga tatagagaaa tttaaagctt ttttagaaaa
      421 agaagagatt cctttagcca tcgcttggca aggggattct ctacatttct acgcgaaaga
      481 ccgttcgatt ttagacaatc atttagacca tcttttagaa aaaatggtta atgatccgga
      541 gaaattagct gattttacca tggataagtc attagatgat gctattgatg aagctaaatc
      601 ccaaattacc tttagacaag aaggagccgt caaacagaaa gagatggtga gatgatgtac
      661 agtggaaaaa aattcctact attctcactg ttaggtatct tactaggcta tctttttcat
      721 cgtttgacgc ttttgtatga ttcctatact ggaaatacct tagataaatg gactcatctt
      781 ctgatggaag gtcaagatga agttcttcag tcgccatgga atgtttcttt tactggaaaa
      841 tcaagtgctt tttttctact aggttttgtg atgatgttac tggtttatct ctatctagag
      901 actggtaaaa aacaataccg agaaggggta gaatacggga gcgcccgttt tggaactcta
      961 aaagaaaaga agctctttta cggtaaggaa ttttctcatg atacgatctt agcacaagat
     1021 gttcgtttga cattattaga taaaaaacca ccccaatatg atagaaataa gaatattgcg
     1081 gtgattggag gttcaggaag tgggaagaca tttcgctttg tgaaacccaa tctgattcag
     1141 atgaatagtt ctaatattgt agtggatcct aaagatcact tggccgagaa aacaggcaaa
     1201 ctctttttag aacatggcta ccaagtaaag gtgttagatt tagtcaatat gaagaactca
     1261 gatggcttta atccttttcg ctatatagaa acagaaaacg atttgaatcg catgctgact
     1321 gtttatttta ataacaccaa aggctctggc tcccgaagtg atccattttg ggatgaagct
     1381 tctatgactt tggttcgagc tttagcctct tacttagtcg atttctataa tccacctaaa
     1441 acaagagaac agctcataga agaaagtcgt ttaagtcaaa aggaatatca aaacttgttg
     1501 aaacgtcaaa aaaaagaagt ggaagagcga aaaaaacgag gtcgttatcc aagttttgct
     1561 gaaatctcaa aactcattaa acacttatct aagggtgaaa accaggaaaa aagtgtctta
     1621 gaaattctat ttgaaaatta tgctaaaaag taagggactg aaaattttac catgcgaaat
     1681 tgggcagatt ttcaaaatta taaggataag actctggatt ctgttatagc tgtaaccact
     1741 gctaaatttg ccctcttcaa tattcaaagt gtcatggact tgaccaaaag agataccctt
     1801 gatatgaaga catggggcaa ggaaaaatca atggtttact tagttatccc agataacgat
     1861 agtacctttc gctttctttc agccctcttt ttttcaaccg tatttcaaac cctaacaaga
     1921 caagcagata ttgattttaa gggtcaattg cctcttcatg tgagagttta cttagatgag
     1981 ttcgcaaata tcggagaaat tccagatttt gctgaacaaa cctcaacagt ccgttctcga
     2041 aatatgagtc tcgttcctat tcttcaaaat attgcccaac ttcaagggct ctataaagaa
     2101 aaagaagctt ggaaaaccat tttggggaac tgtgatagct tagtctactt aggtggtaat
     2161 gatgaagata cctttaaatt tatgagtggc ttactcggta aacaaaccat tgatgttcga
     2221 aatactagtc gttcctttgg ccaaacaggt tcaggatccc tttctcatca aaagattgct
     2281 cgtgacttaa tgacacccga tgaggtcgga aatatgaaac ggcatgaatg cttggttcga
     2341 attgccaata tgcctgtctt taaaagcaaa aaatacaatt ccactaagca tccaaactgg
     2401 aagtacctag ctaatcaaga aagcgatgaa cggtggtgga actatcaaat caatcctttg
     2461 aatcaaagac aagaaaatta tcttgacgac cttagaattc gtgatttaac ttttgaatct
     2521 agtttaaaat aaaaatagaa aagaggaaat agatgattac gcattttaaa ggttttgttt
     2581 atggagtaga cgcaagtgct atgtttgcac aagctatgtc tttgttacag aagggattga
     2641 ttgcagttgg tgcctttctc gttgttgtgg ggattgtcaa ccttgcaacc aacattaaag
     2701 atggtggacc aggtgttcgg aatgccattc ttgaaattgt cggtggtgtt atggtagggg
     2761 ctgctggagc ctttgtaacc cagatttcaa tttaggagga taaacaatga catgaatctt
     2821 agtttagtct caccctttgt ttaccttgca tctgaaaaaa tatcagctga aaatttattt
     2881 gaaggattta atgtggattt acaatctacg gtagatctga ttaaatccct atctagctac
     2941 aatccaacag tttggactta tatgtctagt attactaaaa gtgtcatgca gcctcttgga
     3001 gttgcgattt tatcagttgt tctcatctta gaattttcga agatggcaaa gaagattgct
     3061 aactctggtg gagcgatgac ctttgaagca ttagcgccga tgttgattag ttatattatg
     3121 gtcgcagtgg tcattaccaa tactaccgtt atagtagaag ctatcatcgg gattgcgagt
     3181 cacgccatcg aacaagtggc ctcgattgtg gctcacggtg gggcgaagta tgatacactc
     3241 tctggattaa aaggttcagg atttattggc cggatgattg tgggcttttt cgctctcctt
     3301 atctggcttg ttcggatagt aagtgcagcc atggttaatc ttttggtatc tattcgattt
     3361 attcaactct accttatgat cccatttgcc cctcttacga ttccaacatt tttaagtgat
     3421 gaatggaagt ctattggtat tggctattta aaaaatatta tggtctatgc ggtacaaggg
     3481 gttctcattt ttctgattgt ttctcttgtt cctttgtttg aatctgctgg gaaaatagct
     3541 gtttcaaatg gtgcaggagt cttgcaatca cttgcgatta tgtttggtag tttagtacaa
     3601 gctatcttac tgattattgc cctcgttggt tctcaacgta cggctcgctc aatcttaggt
     3661 atgtaattag ataaaggcta ggaagtgatt gcttcttagc ctttttagaa aggaaagtca
     3721 tgaatacacg tgtctttaaa gacatctcaa aataccaaca cagggcttgg ttaggtttca
     3781 ccacaagaca aatcatcttt gttttaccag cctttattgt cacaattatt gttttgggct
     3841 tgaatctctt tttctggcaa tttggagatt ggtttgttta cggttttgtg tttgctttta
     3901 ccatccccct aatgcttttt ggagtctata aacccaatga tttatatttt gaacattatt
     3961 tgaaataccg tcttcatttt gaattaacgg ttcccctacg cacaattaca ggaaagaaag
     4021 gacctgaaca tgaaaagaaa atcaaataca ttaaagaaac aaaaaacttc aatgactaat
     4081 aaaaaggaag aagttaaagg gaaaaaagag gaagtgttac cctcaacggc taatactctt
     4141 tcctatcaag ccctgtatca aaatggtctg atgcaggtaa aagaagatta tttctcacaa
     4201 agctatttac ttggtgatgt caattaccag accgttggtt tagaagataa gggcgcaatc
     4261 attgagaagt attctgattt gattaactca ctagatgacc aaaccaactt ccaattgact
     4321 atctttaata aaagattgaa tttagaaaag tttagacaaa gtgttttgta tgaggaaaaa
     4381 gaagatggat atgataccta tcgtaaagaa ttgaatcgga tgatgaatca gaatttagat
     4441 agtggtgaaa ataacttttc ggctgtaaaa ctgattagct ttggaagaaa ggattctaat
     4501 cccaaacaag cctatcgttc cttgtctcaa ataggagaat atttcaagag tggtttctca
     4561 gaaattgatg ctcgatttga atccttggct ggagaagatc gtgtgaactt gttggccgac
     4621 atgcttagag gagaacacca tcttcctttt tcttaccgtg atttaacgag atctggtcag
     4681 acaactcgtc acttcatagc ccctaatctc ttggatttta aaaacaagaa ttacctacaa
     4741 atcaatgacc gcttattaca gattgtctat gtcagagact acggcatgga attaggggat
     4801 cagtttattc gagaccttat gcaaggagat ttggaattga ttgtaagcct tcatgctcaa
     4861 agttcgacca aggcagatgc catgaagaaa ctacgaacaa agaagacctt gatggaatcc
     4921 caaaagattg gggaacaaca aaaactagct cgtacaggta tctatttgga aaaagtaggt
     4981 catgtattag aaagtaatat cgatgaagct gaagaacttt taaaaaccat gaccgagaca
     5041 ggtgataaac tgtttcaaac ggtcttcttg attgggatct ttggtcagga tgaagaagaa
     5101 ctcaaacaag ctctagatac gattcaacaa gtggccggct caaatgacct aatgattgat
     5161 aaacttccat atatgcaaga agcagccttt aatagtttgc tgccatttgg ttgtgatttt
     5221 ttagagggag tatcacggag tttattaaca tctaatgtag cagtgaactc accttggact
     5281 tcagtagact tacaagaccg cagtgggaaa tattacggta tcaatcaaat ctcaagcaat
     5341 attattacta ttgatcgaag cttattaaat acaccgtctg gtctgatttt agggacatct
     5401 ggagctggga aagggatggc aactaagcat gagattatca cgaccaaaat caaggaatct
     5461 ggtgaaaata ctgaaattat catcgtggat ccagaagcag aatacagtgt cattggacga
     5521 gcttttgggg gagaaatgat tgatattgcg ccagattccc aaacctatct caatgtactt
     5581 gacttgtctg atgaaaatat ggatgaggat cctgttaagg taaaatcaga atttctttta
     5641 tcctttatcg gcaagttatt ggataggaaa atggatggaa gagaaaaatc gattatcgac
     5701 cgagtcacca gactcaccta tcagtcattt aaagagcctt ctttggaaga atgggtcttt
     5761 gtcttgagtc aacaaccaga agaagaagcg cagaatttgg cacttgatat ggaactgtat
     5821 gtcgaaggtt ctcttgatat tttttctcat aagaccaata ttcagacagg atctaacttc
     5881 ttaatctata acgttaaaaa gttaggagat gagctgaaac aaatcgctct tatggtagtg
     5941 tttgatcaga tatggaatcg tgttgttcgg aaccaaaaat tagggaagaa gacctggatt
     6001 tattttgatg aaatgcagct tctcttatta gataaatatg ccagtgattt cttctttaaa
     6061 ttgtggagtc gtgtcagaaa atatggagct agtccgactg ggataactca aaacgtcgaa
     6121 accttattgt tagatccaaa tggtagacgg attattgcaa atagtgaatt tatgattctc
     6181 ctcaagcaag caaaaaatga ccgagaagaa ctggttcaac tcttaggctt gtcaaaagaa
     6241 ctcgaaaaat accttgtcaa tccagaaaaa ggggcaggac tgataaaagc tggttcagtt
     6301 gtcgtaccct ttaaaaataa gattcctcaa ggtactcaat tgtttgatat catgagtacg
     6361 gatcctgata aaatggcttc taattaaggg gaagtagaat gaaggataaa agaaaaatca
     6421 tacgtgcccg aaaggcattt agaagaagcc taaaagatga gaaaaaattc ttgaaaaaag
     6481 gaaagaagga ggtaaggaaa cagaaaaaag attccgctgt actggatgaa aaagcatgga
     6541 aaaaagagat aaaagaaaag ctagaggaga tgagagaggc ttcaaaggag agagtaaaac
     6601 aagcaaatga agactacaat catattcttc aaaatagtcc tccatctctt ttgaatcgca
     6661 aagaattaag agacagacgg ttgcctcatg ctaggaaacg attgaaaata gccaagaagc
     6721 aatttagaga agccaaggta gaagcaaaag aagaaagaaa agagggtcgt aaagaaagaa
     6781 aaaccaatca aaaatttctc tacggtcagg aatcgaaagc aaaatcaaat tttttctttc
     6841 aagggaagag tttagaagaa ttaaaagcta agaaagaagt caaggacgcc aaagaaaatt
     6901 taaaatctac taaacaagcc tataaatcca aaaaggttag taggaaagcc aaaactttcc
     6961 tttatgtcct tggacgtgaa ggtggagagt tagcttcaga aaatgaagat ttagaaggct
     7021 atcgcacact tcaagagacc attagaaaag ggaaacgcta cagtcggctt tcttataatc
     7081 ttggaaaagc tagtgtcaaa acaggacaag caacaggtcg ttttaccaag aaaagactga
     7141 ccaacacaaa agagcgatac catcatttta aggatggaaa aggatggaaa ctagcgaaag
     7201 ataatccaag ttcctttaaa aatcggtatc gaaaattaaa gaaacaaggc cttacaagtg
     7261 tacgaaatat ctatcaaaaa ctaaaagcag ccttttcctt ctttacattt gcggctggga
     7321 atcctgcaac ctggatagtt ggaggaatag tctttcttct tttacttatg atgagcttct
     7381 ttttaggatt ttcatctgct agtttaattc aacaagatga atttgaatta acaaaagctt
     7441 atacccacct aacttgggaa gacgcagaac atacccgaac caatgacaaa ggaattacct
     7501 attacacaaa agttgatgat gtgatggggt atatgaactt taaattccat gactatgagt
     7561 tacacaaacc agttcactta tttagttcag aaacttacaa ggattatcta tctactttgt
     7621 ggcatgattt aaacgatggg gaagatttga aatccatgca agacctttat gaaactccta
     7681 agtataaact atcgaaagac gatcaagagg aaatgaagga actaaaagaa gaaggtgtgt
     7741 atgcttccat gcaggaattg gacaatccat ttgaagggaa aagtaacgaa gatagtttaa
     7801 ccatgactta tcgttatgga tactatgatt tagacggaaa acctactctt caggagtaca
     7861 ttctactaga agctaaagct caccaagcaa ttgtcgcacc aatggatgga gttgtatctc
     7921 tagatggcga caatgttatt ctcactaacg gaaaaggaga aaacgagagt cgcttaacct
     7981 tatattccat tcataatggc cgtgcgattg aggggacaag agtcctaacg ggtgatgtta
     8041 ttggtgagac accagatgat acaggtttga aagtttccta tcaaaagtat aagaacaaga
     8101 aagaaaaatt ggtgtatgtt aatccgcaat tttattttcc aaaagtcatt caacttcaga
     8161 caactatctt acctgccatt ggtcagtttg gtggggatga gtttgaacga gcgaaacata
     8221 tttatgagtt tttgaaatct caaggggcaa gtccccaagc cattgcagct attttaggaa
     8281 attggtcggt agagtcttct atcaatccta aacgagctga gggagattat ttatctcctc
     8341 cagttggcgc taccgcttcc tcatgggatg atgaaacctg gttagcgatt ggaggtccag
     8401 ccatttatag tggtgcttat cctaatatcc ttcatagagg tttggggtta ggtcaatgga
     8461 cggatactgc agatggttca acacgtcata cagctttatt gaattatgca catagcaaaa
     8521 ataagaagtg gtatgattta gacctccaac ttgattttat gcttcatggg gatagtcctt
     8581 actatcaaag ttggttaaaa gatttcttta aaaatacggg cagtgcagcc aatctcgccc
     8641 aactcttcct cacctattgg gagggaaatt ctggtgacaa actactggaa agacaaacca
     8701 gagcaacgga atggtattac caaattgaaa aaggcttcag ccaaacaaat ggaggacagg
     8761 caaaaagtga cccacaatcc cttgaagggg ttcgtgggga cttgtatgat cattctgttc
     8821 ctggtggtgg agatggtatg gcctatgcct atggacaatg tacatggggc gttgcggctc
     8881 gtatgaacca attaggctta aaattaaaag gaagtaatgg agagaagatt tcaattatta
     8941 ataccatggg aaatggtcag gactgggttg cgacagcttc aagtcttggt ggggaaactg
     9001 gctctacacc aagagcaggt gccattgttt cttttgtggg aggtacacat ggtacaccag
     9061 ccatctacgg tcatgtggct tttgtcgaga aagtatatga tgacggttct ttccttgtgt
     9121 ctgaaaccaa ctatggtggc aaccctaact atacctttag aaaaatctct caagcagata
     9181 gtgcaataag ttttgcctat actacgaaat agaagagttt acacttgaaa ttttaaccat
     9241 tttcaggtag aataaatagt gtagatgagt agtcggctca tggtcaatct gatagtaatc
     9301 ttggacataa gggccaagcg gtggcggaca ccagaacgaa atccgatagc aatcttggac
     9361 gtaagggcca agcggtggca gacaccagaa taaaccgact gactaggtgg cttacagact
     9421 ctgtaaacca ccttttttgt gaggaaaata tggcaaattc tagagattat cgtaatccaa
     9481 attacaccga aaaaataaaa cttcagcgtt tttttactca gttacaaatt gcggcttctt
     9541 tttttaaaga acacttcgtt ggcaaaatca tgtattatga aacagaaata gaaagtgttg
     9601 aacttcattt ttcacctact aatttcatgc acctatgtgg tgttgattac caaaaaggtg
     9661 caggtagttt ctttgacgat tgtttaaata gacatgtcat aattgatgag ttgaaaataa
     9721 aaaaagatgg aaccacgatg caaaagttac aagttttagg atccattgag gagttattgg
     9781 gaaagcatgt tcatctaact ggttcaggac gttatttgta tttggagttt gattatgctc
     9841 tacgtacaag aaaacagata ctagcattaa cattgaaaga gacatcaagg aaaattgttc
     9901 ctcaatcttt attagatttg aagagaaaga cagtatttcc aaaaggtcaa aaagtaattt
     9961 caatttactc aaaacattta caaacgtcgg aactttttta ttatttaaaa gattagttta
    10021 catatctttt gtggcataaa atatattttt atcattttca ggagaacgca gttttggctc
    10081 gttctctttt tttgttgtga tacttctttc aaggaatatt tggtaggatt ggagtgaaaa
    10141 aagattaact aggaaagaag gaagtatatg gaaggcattt atcaacgtga ttcggatcaa
    10201 gatggattaa ctgatgctca agaattggcg ctaggaacca atcctcttag cgcagattct
    10261 gatggtgatg gacgttcaga tttagtggaa gtagaagaag gaaccaatcc cttagaaaag
    10321 gatttacaag acatagacca aacaagtata actgaaccgt cttcagtatt tatggaaatg
    10381 aaacaaaaga tttcagatat gatggagagt cactacaagg aatttataca ggctcttatt
    10441 agtattgaaa cagggattga aaacgaacaa gacctagaag acttatatac ttactacatg
    10501 agaacagatt ctatttctct tttgtctagt gatttagaaa ccagtcctca aaaggttgaa
    10561 atggagatag agttgtaggg gaatcatgtg attctcctat tttcgtatag atgaaaggag
    10621 cgagtatgga agtaatgaaa ttattggcta tgtttcgtgg aacaattcca aaagataggg
    10681 agaaaatgga cctatttctt cgctatcagg cgcaacattt tgatgagaaa tggcaggact
    10741 tggtagagag ttttttggtt gaagagggca agatagaaga gatacctcat gtgtattcgt
    10801 ttcatcaaga tattatttct ttcctagagg ctagttctga aaataatgac caagatttag
    10861 aaagttacac aagaaatttt ggacaagcag gtctaagtaa attatctcaa ttaagtaatt
    10921 ttgagaaaaa cttggtgcta gaagtcgcaa cctataacct ttccactcga ttttatatcc
    10981 aatctgaaaa agagaaacta acaccattaa gtgagcttgt atgtcatcag aaacaggatg
    11041 tcaatttagt caatgtctat cgggttgcga ataatctatc tgaccgcatt agtagagata
    11101 tagaggagtt tcttctaatg gttgactcaa aagagcttaa aaaagaagtt cttgagattc
    11161 attttgaaga aaaagaggga gatgttctag cttatttggg ttcagaattg atggctactt
    11221 tagatactgt tacggatctt gtccatcatg aagaaaacta ccaacaactt ccactgacac
    11281 aaaagctgaa gattattact cattttgatg aagtaaaggc tataagagaa aagtctaagc
    11341 aagtagcgga atccttatct ccttcaagtg atattgaaca ggaaacggaa gaaacgaact
    11401 ccttttctaa tatcgataaa attgtagaag aagctttgag ggaatatcca atcggttcac
    11461 aagtaagtta taaaggacaa gtatttcagt tggtttcgat tgaaaatgca cagttaaatg
    11521 acttagttcg cctagagcta ttcaaagatt ccaaccagtt atttgaagag aatcctatct
    11581 tatacttgaa cagtttggaa gagattgaac aagtattgtc tcatgtagaa cttgaaaaag
    11641 aagattcaga gattgagatt gattcatcaa gtgaaagtca ggaaatagat ttgttttcct
    11701 acctggaaga agaaaatgaa aatgaaaagg aaaaggaaaa ggataaagaa acagaaacgc
    11761 ttattgtagg catagaagag acggatgtcc ctgttcaaga ttttgttttt ccagatgatt
    11821 tagaggactt ttatcctaag acaaatcgag aaaaaattga aacgaatatc gccgcaattg
    11881 aacttgttaa aagattagaa aaagagggac gacaagcgaa tccagaagaa caagagctac
    11941 tagccaagta tgtcggctgg ggtggtcttg ccaatgaatt tttcgatgaa ctcaatccaa
    12001 agtatgaaac agaacgttta actcttaaga gtttagtaag taaatcagag tactccacta
    12061 tgaaacaaag ttctctcaca gcctattata cagacccaat gattattcgc cagatttggc
    12121 aaaaattact ggatgatggt tttgagggag gaaggatatt agatccttct atggggactg
    12181 ggaacttctt tgcggcgatg cctagaagta tacgagataa atcagaactc tatggagttg
    12241 aattagacag tgtgacaggc gcaatcgcaa aacaactcca ccccaatacc catattgaag
    12301 tgcgaggatt tgaagaagtt ccctatcaaa ataatagttt tgatttagtc ttaacgaatg
    12361 ttccttttgg aaattttcgc attgccgata aaaactatga taaaccttac atgattcatg
    12421 attactttgt caaacactca cttgatttag taagagacgg aggacaagtg tcgattatct
    12481 catctatagg gacaatggat aagcggacag ataatgtctt acaagagatt aaatctaaca
    12541 ctcatttttt agggggagtt cgtttgccgg atacggcttt taaaaagatt gcaggtactc
    12601 gagtgaccac agatcttctc ttctttcaaa aggatcaagc aaagaatctt aatgaggagg
    12661 aacttgtctt tagtggctct attccctttg aagaggataa gcgtgtctgg atcaatcctt
    12721 attttgatgg gaaatacaat acacaagttt tgggtcaata tgaggtgcgt aattttaatg
    12781 gaggaactct caatgttaag ggggtatcag aaacattagt tactgaaata atgaaagcat
    12841 tcgagaatgt ggaagcacct aaacaaattg acaattcttt gaaagcacct gtttttatcc
    12901 aagaagaagt agataattct atcccaagtc gtatatgtga ggacttagcg ctctattctt
    12961 ttggatatga gggaaatcaa atttattacc gagatacgca tggcattcgg aaaagttcaa
    13021 aagtagacga aattagttat tatgtagacg agaagggaga atttaaagcc tgggacagtt
    13081 ctttgtctga acataaaata gatcgattcg tgcaacttca tttgacagat gaggaagcac
    13141 tagatgtata caagtcagaa gaagcgagta aaagagggaa atataaggaa ctgttcaaaa
    13201 aaactgtctt ttatgaaagt cccttatcgg ataaggatat tagtcgcatt aagggtatgg
    13261 ttgatttgag agagacctat caagccttaa ttgaaattca acgtcatcca gattatagtc
    13321 ggtctgattt tcagatatta cttagtaaac tcaatcgtga ttatgaccgt tttgtaagtc
    13381 aatttggata cttgaatgcc tcagttaatc ggaacttatt tgatagtgac gataagtatt
    13441 ctttactagc aagtttagaa gatgaataca ttgattctaa agatcagaaa gtaaaatata
    13501 aaaaatcttt agcctttgag aaagcattgg ttaggccgga gagagtgatt acaagagtat
    13561 caacggcttt agatgcctta aactctagtt tatcggatgg tagaggggtt gatttagact
    13621 atatggtatc aatttaccct gaacatagtc aagctgctat tttagatgag ttaggtgacc
    13681 agattttaat ggatccagaa agctatttaa gaggtgaaag aaaatatctt tctaagaacc
    13741 agtttttatc aggagatatt ctcaacaaga tagaagtagt tcaactatta gtagaggaaa
    13801 acaaccaaga atatgattgg aaccatgctt tagatttgtt agaatctgtt cgccctccaa
    13861 ggattcatct ggcagatatt gagtttaaaa tagggtcacg ttggattcct caatccgttt
    13921 acggtaaatt tgcctttgaa tgttttacca atcgtgaatt tgaattgtct tcacctgatg
    13981 ttgaacaagt tattgaagtg aatcctgtcg atgggcaggt tcatttaagg acatcatttg
    14041 cttatcgcta tccaagtgcc aaagatagta gtcttggagt tagtgggtca cgttatgata
    14101 caggaagaaa gatttttgag aatttactta attcgaacca accgacgatt actatgactg
    14161 ttacggaagg agaaaagaaa aagaccatca cagatttgga aaaaacctct gttctaagag
    14221 caaaagagca gcatttacaa gagctctttc aagaatttgt ctcacggtat ccagaagtcc
    14281 aacaagttat tgaggaaagc tataatcgtc tttataatcg aacggtaagt cgagagtatg
    14341 acggtagcca tctagtcatt gatggattgg cacaaaacat cagtcttcgt cctcatcaag
    14401 agaatgccat tcaaagaatc gtagaagaaa aaagagcctt gttagctcat gaggtaggtt
    14461 caggaaagac cttgaccatg cttggtgctg ggtttaaatt aaaggagttg gggatggttc
    14521 ataagccctt gtatgtagta ccttctagtt tgtctgctca atttggccaa gaaatcatga
    14581 aatttttccc tactaaaaaa gtctttgtga ctactaagaa agatttcgtt aaggcaagaa
    14641 gaaaacaatt tgtgtcacgt attattacag gagattacga tgccattgtc attggggatt
    14701 ctcaatttga aaaaatccct gtcagtaagg aaagacagat gaattatatc gaggataaac
    14761 tcaatgaatt acgagagatt aaaacacatt ctgaaaataa gtatactgtt aaagaagcag
    14821 agcaatcaat aagtggtcta gagaaacaat tggaagaact ccaacgcttt aatcgtgata
    14881 gttttattga ttttgagaac ttaggaattg attttctctt tgtggatgaa gcacatcact
    14941 ttaaaaatat tcgtccaatt acgggacttg ggaatgtagc agggattacc aatacaacct
    15001 ctaagaagaa cgtggatatg gaaatgaagg ttcgacagat tcaggaagag catgatttta
    15061 aaaacattgt ctttgcgaca ggaacacctg tttccaattc tattagtgag ttatatacta
    15121 tgatgaacta tattcaacca gatatcttaa aacgctatca agttgattat tttgactctt
    15181 gggtaggtgc ttttggagaa attcaaaact ctatggaatt agctcctaca ggggataagt
    15241 atcagcctaa gaaacgattt aaaaagtttg tcaatctacc tgagttgatg aaaatctata
    15301 aagaaacagc cgacattcaa acacaagata tgttggattt acctgtacca gaagcccata
    15361 ttatccctat tgagagtgag ttaactgaaa accagaaact ctatttagaa gaattggtta
    15421 tgaggtcaga tgcggtcaaa tgtggaacag ttgatccgag ccaggataac atgttaaaga
    15481 ttacgggtga ggcacggaaa ctagctattg atatgcgttt attggactct agctatagtc
    15541 tagcagacaa tcataaactg cttcaggtag ttgataatgt tgaaagaatt tatcgtgagg
    15601 gaatgggaaa taaggctact cagatgattt tttcagatat tggaacacct aagaaaaaag
    15661 ataatggctt tgatgtttat tctgaaataa aggctttatt ggttgataga ggaatcccta
    15721 gtaaggaaat tgcctttgta catgatgcca atagtgatga aaagaagaat agtttgtctc
    15781 gaaaggtcaa tgcaggagaa gtgcggattc ttcttgcatc aactgaaaaa ggaggaacag
    15841 gtttaaatgt tcagagcaag atgaaagcag ttcatcacct ggatgttccg tggagaccaa
    15901 gtgacattca gcaacgcaat ggacggatta tccgacaggg aaatgaaaac aaggaagtgg
    15961 atatttacca ctatattacc aaaggttcgt ttgataatta tctatgggca actcaggaga
    16021 acaaactccg ttatattaag cagattatga cttctaagga gccgattcgt gctgcagaag
    16081 acattgatga gcagaccatg acagcttctg attttaaggc actagcaaca ggtaatcctt
    16141 atctcaaata taagatggaa ctagagaatg atctaactct attagaaaat caaagacgcg
    16201 cctttcaacg cagcaaggat cactatcgtc atacaatctc ttactgtgaa gaaaatatgc
    16261 ccattcttga gaaacgatta agcaagtatg aaggcgatat tcaacagtct gaaatatcga
    16321 aagaccaggc attttctatg acggtaggta agcaagcttt tgatcaacga gctgaagcag
    16381 gtgaatctct acaccgtctt atccgtcata atcaagctga cagcaaagaa tttcgtaccc
    16441 tagcaagcta tcgaggattt gacattaaaa tgcttagtct tccaataaat caacctcttc
    16501 ctgaaacctt ctctgttaag attgtaggag aaaatcagta ttctgtcagt ttagatttgt
    16561 attctccttt ggggacaatt caaaggcttc agcatacaat tgatcacatt aaagaggacc
    16621 aagtgaaaac tcagaactta ttggatgaat taaaggataa atggactact gctaaagttg
    16681 aaattgagaa aaattttcca aaggaagagg attatcaaac taaaaaggcc gaatacgatg
    16741 tactcgcgcc attgattgaa acagaaacgg atttagatat tatagatcag gccttaagac
    16801 aattccacga aaaaggaaaa gaaaagcaag aacaactttc ttttgaatta gattaaaaaa
    16861 tatatataaa tagcggacaa gaaaagaaaa gcgcggtaga ataaagatag aaagaaacga
    16921 ggtaacgatt atgatggaag atacctatta tcaattagaa gaggccttgg tacagggatt
    16981 tcaaacgcct gaagaatacc aagcctacaa ggagctaaag gaacattatg aggaagtgac
    17041 aggcgattac agtttttcta aacgagaact cactagtcaa ttggaaatct ctcttcagaa
    17101 tcatcgaggt gtggactttg aagaacatga aaaagaggag tatttggact tagttcaaaa
    17161 attagaagag tttgattcct ctcttgccac ccattatcgt caattgattg actagaaagg
    17221 agaaagtcat gaatgattta ctccttatcc cagtaatttt tttagcagta ggagggattc
    17281 tcattctttt atggagactc tttcttattg ccagtagact tttcctgatt ggttttgtca
    17341 gttttcttat tttcgtagaa gtctatggaa tttatctgtt ctttactgaa cctactttat
    17401 attttgatga tatcagacaa catggtttaa ctagttttac ggctgtgtac cttttcatca
    17461 atctgatgtt ggttctagga ttcagttggc gcttcattaa ctccatgaat aaggaaaaaa
    17521 tgtgaacttt ttagatagtt aaaagacttt atctgaatct aaattcggat aaggtttttt
    17581 atttgccttg attctttcat atacttcata gctaaattgg agtaataatt tatgaaaatc
    17641 attatcctca ctattattag ttgtatttat ggcttgttta tgtcgttcaa tatgagaaag
    17701 agctcttctc aaattttctt cttttaattt gttcatattt atattataaa ctgaagacag
    17761 ctggttttga catttttctc tgaactgtac gattttgcgc cagaaatgta ggaattacct
    17821 ttcgttgtga tgtgataaaa cttacaagtt ctttttgtta ttcttgacct agtttttata
    17881 gaaagaaggt ctaagatgtt aaataaagtc aaaactaaag ccttaattag tgttggagca
    17941 gtggctgcaa ctagctttat tctcatgatg ggatatactg ctggtcaaca ctcaactgct
    18001 aaacaaagtc gcaaagaaat cgaattggct gcagctaaac ttgtagagga taaacaagca
    18061 gaagataaag ccagcatttt gtcatcggat actgtaaaag aatttttgac tcagtactat
    18121 acgaaagaaa agctcggaga aaataataca cgtattcaac cttatatgac tgaatcggca
    18181 tattctcaag aattgaccag tcaaaacgat gccatgaacc aagtgtataa ggactatatt
    18241 ttggattatc attttgaaaa agctgatatc tttgttaatc agactacgaa tcaagctatt
    18301 gccatggtct cttataatgt aacctatgta tctgatttaa agaatgccaa ccaatcaaag
    18361 actaatcaga cagaaacaag aacagttaag ttatcctatt ctaaactacc aggtaagtta
    18421 ttggtcaatc aagtgcaggt ttggaaatct gggttagatg atttagataa ggtaactcct
    18481 aaaactttag aagaatcatc atcaatacca tcactgccaa atactacgac aaaatgatga
    18541 tattgcatgg aaatagaaga atgtaagcaa atttcaattc ttgatgtagc caatcgttta
    18601 ggtatctcct ttaaacaagt ttctagccgt gtctatgaac atcctgaaca cgattcattt
    18661 cggatttttt caactaccaa tacttttaaa tggttttcaa gagatattca aggtgatgtt
    18721 attgattttg ttcgacttgt taagggaatc tcttttaaag atgctctagc ttttctttct
    18781 gaagaacctt ttcaaaaaga agctgttcaa gaaaaaagag agagaccatt ttattatcct
    18841 ttaaagagag tagaagattc taactgtagt ctggcaagat attacttaac aaaatgtaga
    18901 ggaatctcag aagaaatcgt acaaaagatg attcaacaag gtttgatggc acaagccagt
    18961 tggaaaacaa atgaaactgt tgaacttgtt attgttttta aaagctttga tcatcgtcac
    19021 aagctgcagg cagcaagctt acaagggatt tataagaatc ccgctctttc tagagagagg
    19081 ttaaaaacga ttctaaaagg aagccatgga catattggaa tatcctttga cattggtaaa
    19141 ccaaatagac tggtcttttg tgaatcgttc gtcgacttga tgagctatta cgaacttcat
    19201 caacaaagtc taactgatgt tcgtttggta tctatggagg gattaaaaag gtctgttgtc
    19261 gcttatcaaa ctttacgact gatagctgaa gaaaatcaga agttggaatt tttagataca
    19321 gtaatacctt caaagttatt gcctttgatg aatacaattc gagatacaac tacttatttt
    19381 gataatcatc ccgatttatt aacacttgcg gtagattgtg atgatgcagg aaaagatttt
    19441 tccgataagt tatttcaagc tggattgcct gttttactgg atttacctga taacgaatct
    19501 gggaaagaaa aaatagattg gaatgatatc cttagagaaa agaaatcaga tttacaattg
    19561 atacttgagt ctgcaaaaga gacattgagg aatcaaccag taagacaaac ctctcaatgt
    19621 ttagaattgt gataacaaaa tcaagatgtt ttagctaata ttagaatgaa ggaggatagt
    19681 atatgaccat tattgaacgc ttagaagaaa aggtcactag gcaagaaagt aaggtagcaa
    19741 gagagacaga aaaactagct gcttacaaag agcaactgga gacagcgatg tttgcgacgt
    19801 tcaaaaggcg tcaaagcatt agtcacatga gttttgaaga agctcttgac catgcctttg
    19861 gtaaagaaag acaattcgat gattctgaat ttagaaagga tgaaatgagt gaatgacaaa
    19921 agattggaat tttaatcaac cattagaaag taaatcagaa aatcaagaag atccagataa
    19981 aattgcggct ttatttagaa atcatcaagg aggtaatgat gtaaattatg aagcagcttt
    20041 tcaaaagcgt aaacaagcac ctgtgacgga atcaaattct agttctaaac ccaaagttac
    20101 agaggttaga acaggaaaag agacagatat cactacaagt tatcagcaac atcttaaaag
    20161 actgattgcg gataacaata gcgatattga aagtagtcaa aagaaaattg aagagctaca
    20221 tacgttgatt gacacaaaga ataaagacaa taagaaattg cagtccattt atgatgcgat
    20281 ttcggaatta cactaagcag tctaaagagg ctgctttttt tgagaggtta tagatgttta
    20341 caaaaatttt taagaaaaat caagacaata gtgatatatt taagaagttg attcatagac
    20401 tatctgatat gtctgtccaa gatcttgaaa aaattgacag attgttagat atcattttca
    20461 ctccagaaca agaatcagaa caactaaaaa cagaaacaac ttatagggaa gaaactttgg
    20521 acgacacatt aaaaaaagct aaaaatcaac ttcataagga acaattggag aagaatttag
    20581 agagatttag gaaaaatagt caataacgca ccaaaaatgg tgcatttgct ttttctaaat
    20641 gttataatgg tggtatcaaa taaaaggagt ttgccatgat tggaaagaac ataaaatcct
    20701 tacgtaaaac acatgactta acacaacacg actttgcacg gattgtaggt atttcacgaa
    20761 atagtctgag tcgttatgaa aatggaacga gttcagtctc taccgaatta atagacatca
    20821 tttgtcagaa gtttaatgta tcttatgtcg atattgtagg agaagataaa atgctcaatc
    20881 ctgttgaaga ttatgaattg actttgaaaa ttgaaattgt gaaagaaaga g
//
LOCUS       DAVBOG010000037        20659 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.037, whole genome shotgun sequence.
ACCESSION   DAVBOG010000037 DAVBOG010000000
VERSION     DAVBOG010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20659)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20659)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20659
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.037"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            163..2145
                     /locus_tag="VQ865_001511"
     CDS             163..2145
                     /locus_tag="VQ865_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3135836.1"
                     /translation="MKSSKLFALAGVTLLAATTLAACSGSGSSTKGEKTFSYIYETDP
                     DNLNYLTTAKAATANITSNVVDGLLENDRYGNFVPSMAEDWSVSKDGLTYTYTIRKDA
                     KWYTSEGEEYAAVKAQDFVTGLKYAADKKSDALYLVQESIKGLDAYVKGEIKDFSQVG
                     IKALDEQTVQYTLNKPESFWNSKTTMGVLAPVNEEFLNSKGDDFAKATDPSSLLYNGP
                     YLLKSIVTKSSVEFAKNPNYWDKDNVHVDKVKLSFWDGQDTSKPAENFKDGSLTAARL
                     YPTSASFAELEKSMKDNIVYTQQDSITYLVGTNIDRQSYKYTSKTSDEQKASTKKALL
                     NKDFRQAIAFGFDRTAYASQLNGQTGASKILRNLFVPPTFVQADGKNFGDMVKEKLVT
                     YGDEWKDVNLADSQDGLYNPEKAKAEFAKAKSALQAEGVQFPIHLDMPVDQTATTKVQ
                     RVQSMKQSLEATLGADNVIIDIQQLQKDEVNNITYFAENAAGEDWDLSDNVGWGPDFA
                     DPSTYLDIIKPSVGESTKTYLGFDSGEDNVAAKKVGLYDYEKLVTEAGDEATDVAKRY
                     DKYAAAQAWLTDSALIIPTTSRTGRPILSKMVPFTIPFALSGNKGTSEPVLYKYLELQ
                     DKAVTVDEYQKAQEKWMKEKEESNKKAQEDLAKHVK"
     gene            2446..7749
                     /locus_tag="VQ865_001512"
     CDS             2446..7749
                     /locus_tag="VQ865_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001032503.1"
                     /note="The YSIRK form of extended signal peptide directs
                     nascent proteins to the cross-wall site, while signal
                     peptides lacking YSIRK direct proteins instead to the cell
                     pole. A large fraction of YSIRK proteins are surface
                     proteins anchored by sortase-mediated processing of a
                     C-terminal LPXTG motif; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-type signal peptide-containing protein"
                     /protein_id="HET3135837.1"
                     /translation="MNKGLFEKRCKYSIRKFSLGVASVMIGAAFFGTSPVLADSVQSG
                     STANLPADLATALATAKENDGRDFEAPKVGEDQGSPEVTDGPKTEEELLALEKEKPAE
                     EKPKEDKPAAAKPETPKTVTPEWKTVEKKEQKGTVTIREEKGVRYNQLSSTAQNDNAG
                     KPALFEKKGLTVDANGNATVDLTFKDDSEKGKSRFGVFLKFKDTNNNVFVGYDKDGWF
                     WEYKSPTTSTWYRGSRVAAPETGSTNRLSITLKSDGQLNASNNDVNLFDTVTLPAAVN
                     DHLKNEKKILLKAGSYDDERTVVSVKTDNQEGVKTEDTPAEKETGPEVDDSKVTYDTI
                     QSKVLKAVIDQAFPRVKEYTLNGHTLPGQVQQFNQVFINNHRITPEVTYKKINETTAE
                     YLMKLRDDAHLINAEMTVRLQVVDNQLHFDVTKIVNHNQVTPGQKIDDERKLLSSISF
                     LGNALVSVSSDQTGAKFDGATMSNNTHVSGDDHIDVTNPMKDLAKGYMYGFVSTDKLA
                     AGVWSNSQNSYGGGSNDWTRLTAYKETVGNANYVGIHSSEWQWEKAYKGIVFPEYTKE
                     LPSAKVVITEDANADKNVDWQDGAIAYRSIMNNPQGWEKVKDITAYRIAMNFGSQAQN
                     PFLMTLDGIKKINLHTDGLGQGVLLKGYGSEGHDSGHLNYADIGKRIGGVEDFKTLIE
                     KAKKYGAHLGIHVNASETYPESKYFNEKILRKNPDGSYSYGWNWLDQGINIDAAYDLA
                     HGRLARWEDLKKKLGDGLDFIYVDVWGNGQSGDNGAWATHVLAKEINKQGWRFAIEWG
                     HGGEYDSTFHHWAADLTYGGYTNKGINSAITRFIRNHQKDAWVGDYRSYGGAANYPLL
                     GGYSMKDFEGWQGRSDYNGYVTNLFAHDVMTKYFQHFTVSKWENGTPVTMTDNGSTYK
                     WTPEMRVELVDADNNKVVVTRKSNDVNSPQYRERTVTLNGRVIQDGSAYLTPWNWDAN
                     GKKLSTEKEKMYYFNTQAGTTTWTLPSDWAKSKVYLYKLTDQGKTEEQELTVKDGKIT
                     LDLLANQPYVLYRSKQTNPEMSWSEGMHIYDQGFNSGTLKHWTISGDASKAEIVKSQG
                     ANDMLRIQGNKEKVSLTQKLTGLKPNTKYAVYVGVDNRSNAKAIITVNTGEKEVTTYT
                     NKSLALNYVKAYAHNTRRDNATVDDTSYFQNMYAFFTTGSDVSNVTLTLSREAGDEAT
                     YFDEIRTFENNSSMYGDKHDTGQGTFKQDFENVAQGIFPFVVGGVEGVEDNRTHLSEK
                     HDPYTQRGWNGKKVDDVIEGNWSLKTNGLVSRRNLVYQTIPQNFRFEAGKTYRVTFEY
                     EAGSDNTYAFVVGKGEFQSGRRGTQASNLEMHELPNTWTDSKKAKKATFLVTGAETGD
                     TWVGIYSTGNASNTRGDSGGNANFRGYNDFMMDNLQIEEITLTGNMLTENALKNYLPT
                     VAMTNYTKESMDALKEAVFNLSQADDDISVEEARAEIAKIETLKNALVQKKTALVADD
                     FASLTAPAQAQEGLANAFDGNLSSLWHTSWNGGDVGKPATMVLKEPTEITGLRYVPRG
                     SGSNGNLRDVKLVVTDESGKEHTFTATDWPDNNKPKDIDFGKTIKAKKIVLTGTKTYG
                     DGGDKYQSAAELIFTRPQVAETPLDLSGYEAALTKAQKLTDKDNQEEVASVQASMKYA
                     TDNHLLTERMVEYFADYLNQLKDSATKPDAPTVEKPEFKLSSLASEQGKTPDYKQEIA
                     RPETPEQILPATGESQSDTALFLAGVSLALSALFVVKTKKD"
     gene            complement(7916..10075)
                     /locus_tag="VQ865_001513"
     CDS             complement(7916..10075)
                     /locus_tag="VQ865_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HET3135838.1"
                     /translation="MNKPTILRLIKYLSISFLSLVIAAIVLGGGVFFYYVSKAPSLSE
                     SKLVATTSSKIYDNKNQLIADLGSERRVNAQANDIPTDLVKAIVSIEDHRFFDHRGID
                     TIRILGAFLRNLQSNSLQGGSTLTQQLIKLTYFSTSTSDQTISRKAQEAWLAIQLEQK
                     ATKQEILTYYINKVYMSNGNYGMQTAAQNYYGKDLNNLSLPQLALLAGMPQAPNQYDP
                     YSHPEAAQDRRNLVLSEMKNQGYISAEQYEKAVNTPITDGLQSLKSASNYPAYMDNYL
                     KEVINQVEEETGYNLLTTGMDVYTNVDQEAQKHLWDIYNTDEYVAYPDDELQVASTIV
                     DVSNGKVIAQLGARHQSSNVSFGINQAVETNRDWGSTMKPITDYAPALEYGVYDSTAT
                     IVHDEPYNYPGTNTPVYNWDRGYFGNITLQYALQQSRNVPAVETLNKVGLNRAKTFLN
                     GLGIDYPSIHYSNAISSNTTESDKKYGASSEKMAAAYAAFANGGTYYKPMYIHKVVFS
                     DGSEKEFSNVGTRAMKETTAYMMTDMMKTVLSYGTGRNAYLAWLPQAGKTGTSNYTDE
                     EIENHIKTSQFVAPDELFAGYTRKYSMAVWTGYSNRLTPLVGNGLTVAAKVYRSMMTY
                     LSEGSNPEDWNIPEGLYRNGEFVFKNGARSTWSSPAPQQPPSTESSSSSSDSSTSQSS
                     STTPSTNNSTTTNPNNNTQQSNTTPDQQNQNPQSAQP"
     gene            complement(10072..10668)
                     /gene="recU"
                     /locus_tag="VQ865_001514"
     CDS             complement(10072..10668)
                     /gene="recU"
                     /locus_tag="VQ865_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HET3135839.1"
                     /translation="MVNYPHKVSSQKRQTSLSQPKNFANRGMSFEKMINATNDYYLSQ
                     GLAVIHKKPTPIQIVQVDYPQRSRAKIVEAYFRQASTTDYSGVYNGYYIDFEVKETKQ
                     KRAIPMKNFHPHQIQHMEQVLAQQGICFVLLHFSSQQETYLLPAFDLIRFYHQDKRQK
                     SMPLEYIREYGYEIKAGAFPQIPYLNVIKEHLLGGKTR"
     gene            10734..11261
                     /locus_tag="VQ865_001515"
     CDS             10734..11261
                     /locus_tag="VQ865_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000179549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HET3135840.1"
                     /translation="MATALVLGYSAFDLGLFSDKDPRLKLIKKAIRKDLEAMAADGVS
                     WLVFTGSLGFEYWVLEVAQEMKTEYGFQLATIFAFETHGENWNEGNQMKLSRFKQVDF
                     VKYAYPRYEHKGQLRDYQQFLLENTTSSYLFYDEENETKLAYFYQKMKNQEDYFIKRL
                     TFDELNELAENFSEN"
     gene            11331..11660
                     /gene="gpsB"
                     /locus_tag="VQ865_001516"
     CDS             11331..11660
                     /gene="gpsB"
                     /locus_tag="VQ865_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000146522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HET3135841.1"
                     /translation="MASIIFSAKDIFEQEFGREVRGYNKVEVDEFLDDVIKDYETYAA
                     LVKSLRQEIADLKEELTRKPKPSPVQAEPLEAAITSSMTNFDILKRLNRLEKEVFGKQ
                     ILDNSDF"
     gene            11681..12061
                     /gene="rnpB"
                     /locus_tag="VQ865_001517"
     ncRNA           11681..12061
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="VQ865_001517"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            12146..13303
                     /locus_tag="VQ865_001518"
     CDS             12146..13303
                     /locus_tag="VQ865_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000711388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HET3135842.1"
                     /translation="MKKEFNLIATVAAGLEAVVGREVRELGYDCQVENGRVRFQGDVR
                     AIIETNLWLRAADRIKIIVGTFPAKTFEELFQGVFALDWENYLPLGARFPISKAKCVK
                     SKLHNEPSVQAISKKAVVKKLQKHYARPEGVPLMENGPEFKIEVSILKDVATVMIDTT
                     GSSLFKRGYRTEKGGAPIKENMAAAILQLSNWYPDKPLIDPTCGSGTFCIEAVMIARK
                     MAPGLRRSFAFEEWNWISDRLIQEVRTEAAKKVERELELDIMGCDIDARMVEIAKANA
                     QAAGVAGDITFKQMRVQDLRSDKINGVIISNPPYGERLSDDAGVTKLYAEMGQVFAPL
                     KTWSKFILTSDEAFESKYGSQADKKRKLYNGTLKVDLYQYFGQRVKRQEVK"
     gene            13316..14710
                     /gene="mapZ"
                     /locus_tag="VQ865_001519"
     CDS             13316..14710
                     /gene="mapZ"
                     /locus_tag="VQ865_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000039255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mid-cell-anchored protein MapZ"
                     /protein_id="HET3135843.1"
                     /translation="MSKKRRNRHKKEGQEPQFDFDEAKELTVGQAIRKNEEVEAGVLP
                     EDSILDKYVKQHRDEIEADKFATRQYKKEEFVETQSLDDLIQEMREAVEKSEASSEEV
                     PSSEDILLPLPLDDEEQGLDPLLLDDENPTEMTEEVEEEQNLSRLDQEDSEKKSKKGF
                     ILTVLALVSVIICVSAYYVYRQVARSTKEIETSQSTTANQSDVDDFNTLYDAFYTDSN
                     KTALKNSQFDKLSQLKTLLDKLEGSREHTLAKSKYDSLATQIKAIQDVNAQFEKPAIV
                     DGVLDTNAKAKSDAKFTDIKTGNTELDKVLDKAISLGKSQQTSTSSSSSSQTSSSSSS
                     QASSNTTSEPKPSSSNETRSSRSEVNMGLSSAGVAVQRSASRVAYNQSAIDDSNNSAW
                     DFADGVLEQILATSRSRGYITGDQYILERVNIVNGNGYYNLYKPDGTYLFTLNCKTGY
                     FVGNGAGHADDLDY"
     gene            14786..16210
                     /gene="gndA"
                     /locus_tag="VQ865_001520"
     CDS             14786..16210
                     /gene="gndA"
                     /locus_tag="VQ865_001520"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004185725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HET3135844.1"
                     /translation="MTKANFGVVGMAVMGRNLALNIESRGYTVAIYNRSKEKTEDVIA
                     CHPEKNFVPSYDVESFVNSIEKPRRIMLMVQAGPGTDATIQALLPHLDKGDILIDGGN
                     TFYKDTIRRNEELANSGINFIGTGVSGGEKGALEGPSIMPGGQKEAYELVADVLEEIS
                     AKAPEDGKPCVTYIGPDGAGHYVKMVHNGIEYGDMQLIAESYDLMQHLLGLSAEDMAE
                     IFTEWNKGELDSYLIEITADILSRKDDEGQDGPIVDYILDAAGNKGTGKWTSQSSLDL
                     GVPLSLITESVFARYISTYKEERVHASKVLPKPAAFNFEGDKAELIEKIRQALYFSKI
                     ISYAQGFAQLRVASKENNWNLPFADIASIWRDGCIIRSRFLQKITDAYNRDADLANLL
                     LDEYFLDVTAKYQQAVRDIVALAVQAGVPVPTFSAAITYFDSYRSADLPANLIQAQRD
                     YFGAHTYQRKDKEGTFHYSWYDEK"
     gene            16222..16911
                     /locus_tag="VQ865_001521"
     CDS             16222..16911
                     /locus_tag="VQ865_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000518023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3135845.1"
                     /translation="MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQ
                     TDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMILDHWEDLQEELEVVQRFAVSYIY
                     KPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
                     REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIK
                     TVRGVGYTMQE"
     gene            17009..18028
                     /gene="cbpC"
                     /locus_tag="VQ865_001522"
     CDS             17009..18028
                     /gene="cbpC"
                     /locus_tag="VQ865_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000771060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline-binding protein CbpC"
                     /protein_id="HET3135846.1"
                     /translation="MKLLKKMMQVLLAVFFFGLLATNTVFANTTGGRFVDKDNRKYYV
                     KDDHKAIYWHKIDGKTYYFGDIGEMVVGWQYLEIPGTGYRDNLFDNQPVNEIGLQEKW
                     YYFGQDGALLEQTDKQVLEAKTSENTGKVYGEQYPLSAEKRTYYFDNNYAVKTGWIYE
                     DGNWYYLNKLGNFGDDSYNPLPISEVAKGWTQDFHVTIDIDRSKPAPWYYLDPETGIM
                     RTGWQYLGNNWYYLRSSGAMATGWYQEGTTWYYLDQPNGDMKTGWQNLGNKWYYLRSS
                     GAMATGWYQDGSTWYYLNAGNGDMKTGWFQVNGNWYYAYSSGALAVNTTVDGYSVNYN
                     GEWVR"
     gene            complement(18146..19378)
                     /locus_tag="VQ865_001523"
     CDS             complement(18146..19378)
                     /locus_tag="VQ865_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000765682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3135847.1"
                     /translation="MKLFWTNNIYRQLLLNSCFSSFGDSIFYLAIINYVAQYNFAPLA
                     ILLISISEMVPLLSQLFLGILGDFQENRVKHALCIAKIKILLYAILTVFLVLSPFSLV
                     SVIMIVIINLISDTLSYLSAYMMNALYISVIKDDLHDAMGFRQSLMRVVRIVANLAGA
                     FLINVISIQTISLINTLTFVIAFLGLYVIRHTLYEVEKRIEMSHTALSFKKYFQHLKQ
                     SLAVLLKLKDTVILLFLTTSMIAILDVSPRLIALRFIQQTLAQLSIGQLLALLSIIMS
                     CGAILGNMTSSNLFKNIRFTHLLVFCEISLLALITSILCQAYIVIFMTSFISSTIIGI
                     LSPRLQAAVFAYIPSDKMGTVGSALSTVDILAPSLLSLLALSIASGVSVQLALIFLYL
                     ILIALIFCQWLVKFNTHN"
     gene            complement(19538..20008)
                     /locus_tag="VQ865_001524"
     CDS             complement(19538..20008)
                     /locus_tag="VQ865_001524"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135848.1"
                     /translation="MTILLKLSSTIVYGEIYHYFLQRDTAKESILDYSFAHGYCGIAY
                     ALFAYSKVLEPSMFYNDLHTFHTELKKLLEKVTSNTENLGNLQLSWCKGISGIILYLC
                     MYDCDGNKDIISKYQEFVFNHHLKMMTGYCHGITSLLQTTVYNQNKLLMKKSNR"
     gene            complement(20175..20585)
                     /locus_tag="VQ865_001525"
     CDS             complement(20175..20585)
                     /locus_tag="VQ865_001525"
                     /inference="COORDINATES: protein motif:HMM:NF017000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135849.1"
                     /translation="MQLLELSHTQGQLTDEQLFWLQCLLNLSQTNNLVKIKKIEEHKY
                     DYKTECNSVLRFLLDKTVNSEGRITSSTEFGNFVSNLSFQHGIAGLLFPLNKLYHPEL
                     DSKILSIIKKAVTIRTSHTYEYQYSLLFGGAGYL"
BASE COUNT         6424 a         3740 c         4633 g         5862 t
ORIGIN      
        1 agtctggaga tttttcaata gacttcgtta ttgggcggtt acgatattca tattttttgc
       61 aaagatgttg tttgaaaaat aattttcaaa aattctgaaa attctgttga catctttctg
      121 aaaagagtct ataatggaga gaaagtttta aaggagaaaa tgatgaaaag ttcaaaacta
      181 tttgcccttg cgggcgtgac attattggcg gcgactactt tagctgcatg ctctggatca
      241 ggttcaagta ctaaaggtga gaagacattc tcatacattt atgagacaga ccctgataac
      301 ctcaactatt tgacaactgc taaggctgcg acagcaaata ttaccagtaa cgtggttgat
      361 ggtttgctag aaaatgatcg ctacgggaac tttgtgccgt ctatggctga ggattggtct
      421 gtatccaagg atggattgac ttacacttat actatccgta aggatgcaaa atggtatact
      481 tctgaaggtg aagaatacgc ggcagtcaaa gctcaagact ttgtaacagg actaaaatat
      541 gctgctgata aaaaatcaga tgctctttac cttgttcaag aatcaatcaa agggttggat
      601 gcctatgtaa aaggggaaat caaagatttc tcacaagtag gaattaaggc tctggatgaa
      661 cagacagttc agtacacttt gaacaaacca gaaagcttct ggaattctaa gacaaccatg
      721 ggtgtgcttg cgccagttaa tgaagagttt ttgaattcaa aaggagatga ttttgccaaa
      781 gctacggatc caagtagtct cttgtataac ggtccttatt tgttgaaatc cattgtgacc
      841 aaatcctctg ttgaatttgc gaaaaatccg aactactggg ataaggacaa tgtgcatgtt
      901 gacaaagtta aattgtcatt ctgggatggt caagatacca gcaaacctgc agaaaacttt
      961 aaagatggta gccttacagc agctcgtctc tatccaacaa gtgcaagttt cgcagagctt
     1021 gagaagagta tgaaggacaa tattgtctat actcaacaag actctattac gtatctagtt
     1081 ggtacaaata ttgaccgtca gtcctataaa tacacatcta agaccagcga cgaacaaaag
     1141 gcatcgacta aaaaggctct cttaaacaag gatttccgtc aggctattgc ctttggattt
     1201 gaccgtacag cctatgcctc tcagttgaat ggacaaactg gagcaagtaa aatcttgcgt
     1261 aatctctttg tgccaccaac atttgttcaa gcagatggta aaaactttgg cgatatggtc
     1321 aaagagaaat tggtcactta tggggatgaa tggaaggatg ttaatcttgc agattctcag
     1381 gatggtcttt acaatccaga aaaagccaag gctgaatttg ctaaagctaa atcagcctta
     1441 caagcagaag gagtccaatt cccaattcat ttggatatgc cagttgacca gacagcaact
     1501 acaaaagttc agcgcgtcca atctatgaaa caatccttgg aagcaacttt aggagctgat
     1561 aatgtcatta ttgatatcca acaactacaa aaagacgaag taaacaatat tacatatttt
     1621 gctgaaaatg ctgctggcga agattgggat ttatcagata atgtcggttg gggtccagac
     1681 tttgccgatc catcaaccta ccttgatatc atcaaaccat ctgtaggaga aagtactaaa
     1741 acatatttag ggtttgactc aggggaagat aatgtagctg ctaaaaaagt aggtctatat
     1801 gactacgaaa aattggttac tgaggctggt gatgaggcta cagatgttgc taaacgctat
     1861 gataaatacg ctgcagccca agcttggttg acagatagtg ctttgattat tccaactaca
     1921 tctcgtacag ggcgtccaat cttgtctaag atggtaccat ttacaatacc atttgcattg
     1981 tcaggaaata aaggtacaag tgaaccagtc ttgtataaat acttggaact tcaagacaag
     2041 gcagtcactg tagatgaata ccaaaaagct caggaaaaat ggatgaaaga aaaagaagag
     2101 tctaataaaa aggctcaaga agatctcgca aaacatgtga aataactgtt gcaaaatata
     2161 agaaaggatt tagtatttct cttgaatgct gaatcctttt ttacatttgt aaagaaagct
     2221 tctaaatgta ctgaccccca aaagttggag cctctttttg tcagaataga gaaaattttt
     2281 gttaatttta cttgtttcct attgctttct cagttattat ttgttatatt aaaagtataa
     2341 ttatttttta tttatcaggg ttaagcattg cactttcaga ggaaggagta ttttttaaaa
     2401 aggaaatgta aacgcttgct aaaaaatgaa aggatttaga agtttatgaa taaaggatta
     2461 tttgaaaaac gttgtaaata tagtattcgg aaattttcat taggtgttgc ttctgttatg
     2521 attggagctg cattctttgg gacaagtccg gttcttgcag atagcgtgca gtctggttcc
     2581 acggcgaact taccagctga tttagctact gctcttgcaa cagcaaaaga gaatgatgga
     2641 cgtgattttg aagcgcctaa ggtgggagaa gaccaaggtt ctccagaagt tacagatgga
     2701 cctaagacag aagaagaact attagcactt gaaaaagaaa aaccggctga agaaaaacca
     2761 aaagaggata aacctgcagc tgctaaacct gaaacaccta agacggtaac ccctgaatgg
     2821 aaaacggtag agaaaaaaga acaaaaggga acagtcacta tccgagaaga aaaaggtgtc
     2881 cgctacaacc aactatcctc aactgctcaa aatgataacg caggtaaacc agccctgttt
     2941 gaaaagaagg gcttgaccgt tgatgccaat ggaaatgcaa ctgttgattt aaccttcaaa
     3001 gatgattctg aaaagggcaa atcacgcttt ggtgtcttct tgaaatttaa agataccaat
     3061 aataatgttt ttgtcggtta tgacaaggat ggctggttct gggagtataa atctccaaca
     3121 actagcactt ggtatagagg tagtcgtgtt gctgctcctg aaacaggatc aacaaaccgt
     3181 ctctctatca ctctcaagtc agacggtcag ctaaatgcca gcaataacga tgtcaatctc
     3241 tttgacacag tgactctacc agctgcggtc aatgaccatc ttaaaaatga gaagaagatc
     3301 cttctcaagg cgggctctta tgacgatgag cgaacagttg ttagcgttaa aacggataac
     3361 caagaggggg taaaaacaga ggatacccct gctgaaaaag aaacaggtcc tgaagttgat
     3421 gatagcaagg tgacttatga cacgattcag tctaaggtcc tcaaagcagt gattgaccaa
     3481 gccttccctc gtgtcaagga atacaccttg aatggacata ctttgccagg acaggtgcaa
     3541 cagttcaacc aagtctttat caataaccac cgaatcaccc ctgaagtcac ttataagaaa
     3601 atcaatgaga caacagcaga gtacttgatg aagcttcgcg atgatgctca cttaatcaat
     3661 gcggaaatga cagtacgctt gcaagttgtg gacaatcaat tgcactttga tgtgaccaag
     3721 attgtcaacc acaatcaagt cactccaggt caaaagattg atgacgaaag aaaactactt
     3781 tcttctatta gtttcctcgg caatgcttta gtctctgttt ctagtgatca aactggtgct
     3841 aagtttgatg gggcaaccat gtcaaacaat acgcatgtca gcggagatga tcatatcgat
     3901 gtaaccaatc caatgaagga tttggctaag ggttacatgt atggatttgt ttctacagat
     3961 aagcttgctg ctggtgtttg gagtaactct caaaacagct atggtggtgg ttcgaatgac
     4021 tggactcgtt tgacagctta taaagaaaca gtcggaaatg ccaactatgt aggaatccac
     4081 agctctgaat ggcaatggga aaaagcttat aagggcattg ttttcccaga atacacgaag
     4141 gaacttccaa gtgctaaggt tgttatcact gaagatgcca atgcagacaa gaacgttgat
     4201 tggcaagatg gtgccattgc ttatcgtagc attatgaaca atcctcaagg ttgggaaaaa
     4261 gttaaggata tcacagctta ccgtatcgcg atgaactttg gttctcaagc acaaaaccca
     4321 ttccttatga ccttggatgg tatcaagaaa atcaatctcc atacagatgg tcttgggcaa
     4381 ggtgttctcc ttaaaggata tggtagcgaa ggccatgact ctggtcactt gaactatgct
     4441 gatattggta agcgtatcgg tggtgtcgaa gacttcaaga ccctaattga gaaggctaag
     4501 aaatatggag ctcatctagg tatccacgtt aacgcttcag aaacttatcc tgagtctaaa
     4561 tacttcaatg aaaaaattct ccgtaagaat ccagatggaa gctatagcta tggttggaac
     4621 tggctagatc aaggtatcaa cattgatgct gcctatgacc tagctcatgg tcgtttggca
     4681 cgttgggaag atttgaagaa aaaacttggt gacggtctcg actttatcta tgtggacgtt
     4741 tggggtaatg gtcaatcagg tgataacggt gcctgggcta cccacgttct tgctaaagaa
     4801 attaacaaac aaggctggcg ctttgcgatc gagtggggcc atggtggtga gtacgactct
     4861 accttccatc actgggcagc tgacttgacc tacggtggct acaccaataa aggtatcaac
     4921 agtgccatca cccgctttat ccgtaaccac caaaaagatg cttgggtagg ggactacaga
     4981 agttatggtg gtgcagccaa ctatccactg ctaggtggct acagcatgaa agactttgaa
     5041 ggctggcaag gaagaagtga ctacaatggc tatgtgacta acctctttgc tcatgacgtc
     5101 atgactaagt acttccaaca cttcactgta agtaaatggg aaaatggtac accggtgact
     5161 atgaccgata acggtagcac ctataaatgg actccagaaa tgcgagtgga gttggtagat
     5221 gctgacaata ataaagtagt tgtaactcgt aagtcaaatg atgtcaatag cccacaatat
     5281 cgcgaacgta cagtaacgct caacggacgt gtcatccaag atggttcagc ttacttgact
     5341 ccttggaact gggatgcaaa tggtaagaaa ctttctactg agaaggaaaa gatgtactac
     5401 ttcaatacgc aggccggtac aacaacttgg acccttccaa gcgattgggc aaagagcaag
     5461 gtttaccttt acaagctaac tgaccaaggt aagacagaag agcaagaact aactgtaaaa
     5521 gatggtaaaa ttaccctaga tcttctagca aatcaaccat acgttctcta tcgttcgaaa
     5581 caaaccaatc ctgaaatgtc atggagtgaa ggcatgcaca tctatgacca aggatttaat
     5641 agcggtacct tgaaacattg gaccatttca ggcgatgctt ctaaggcaga aattgtcaag
     5701 tctcaagggg caaacgatat gcttcgtatt caaggaaaca aagaaaaagt tagtctcact
     5761 cagaaattaa ctggcttgaa accaaatacc aagtatgccg tttatgtcgg tgtcgataac
     5821 cgtagtaatg ccaaggcgat catcactgta aacactggtg aaaaagaagt gactacttat
     5881 accaataagt ctctcgctct caactatgtt aaggcctacg cccacaatac acgtcgtgac
     5941 aatgctacag ttgacgatac aagttacttc caaaacatgt acgccttctt tacaactgga
     6001 tcggacgtct caaatgttac tctgacattg agtcgtgaag ctggtgatga agcaacttac
     6061 tttgatgaaa ttcgtacctt tgaaaacaat tcaagcatgt acggagacaa gcatgataca
     6121 ggtcaaggaa ccttcaagca agactttgaa aatgttgctc agggtatctt cccatttgta
     6181 gtgggtggtg tcgaaggtgt cgaagacaac cgcactcact tgtctgaaaa acacgatcca
     6241 tatacacaac gtggttggaa cggtaagaaa gttgatgatg ttatcgaagg aaattggtca
     6301 ctcaagacaa atggactagt gagccgtcgt aacttggttt accaaactat tccgcaaaac
     6361 ttccgttttg aagcaggtaa gacctaccgt gtaacctttg aatacgaagc aggttcagac
     6421 aatacctatg cttttgtagt cggtaaggga gaattccagt caggtcgtcg tggtactcaa
     6481 gcaagcaact tggaaatgca tgaattgcca aatacttgga cagattctaa gaaagccaag
     6541 aaggcaacct tcctcgtgac aggtgcagaa acaggggata cttgggtagg tatctactca
     6601 actggaaatg caagtaatac tcgtggtgat tctggtggaa atgccaactt ccgtggttat
     6661 aacgacttca tgatggataa tcttcaaatc gaagaaatta ccctaacagg taatatgttg
     6721 acagaaaatg ctctgaagaa ctacttgcca acggttgcca tgactaacta caccaaagag
     6781 tctatggatg ctttgaaaga ggcggtcttt aaccttagtc aggccgatga tgatatcagt
     6841 gtggaagaag cgcgtgcaga gattgccaag attgaaacct tgaagaatgc tttggttcag
     6901 aagaaaacgg ctttggtagc agatgacttt gcaagtctta cagctcctgc tcaggctcaa
     6961 gaaggtcttg caaatgcctt tgatggaaac ttatctagtc tatggcatac atcttggaat
     7021 ggtggagatg taggcaagcc tgcaaccatg gtcttgaaag aaccaactga aatcactgga
     7081 cttcgttatg ttccacgtgg atcaggttca aatggtaact tgcgtgatgt gaaacttgtt
     7141 gtgacagatg agtctggcaa ggagcatacc tttactgcaa ctgattggcc agataacaat
     7201 aagccaaaag acattgattt tggtaagaca attaaggcta agaaaattgt ccttacaggt
     7261 actaagactt acggagatgg tggcgataaa taccaatctg cagcggaact catctttact
     7321 cgtccacagg tagcagaaac acctcttgac ttgtcaggct atgaagcagc tttgactaag
     7381 gctcagaaat taacagacaa agacaatcaa gaggaagtag ctagcgttca ggcaagcatg
     7441 aaatatgcga cggataacca tctcttgacg gaaagaatgg tggaatactt tgcagattat
     7501 ctcaaccaat taaaagattc tgctacgaaa ccagatgctc caactgtaga gaaacctgag
     7561 tttaaactta gctctttagc ttccgagcaa ggtaagacgc cagattataa gcaagaaata
     7621 gctagaccag aaacacctga acaaatcttg ccagcaacag gtgagagtca atctgacaca
     7681 gccctcttcc tagcaggtgt tagcctagcc ctatctgctc tctttgtagt aaaaacgaag
     7741 aaagactagt atttagtaaa acctcttaac aagattacgg aagcagtctc tatcttttcc
     7801 aatgaggttt atagtacaga aaaagcctga gaagatgtct tctcaggctt ttgttaagca
     7861 cataaataca atagtgctat gaaaaaatca cccagaaaaa tctgggtgat aaatgttatg
     7921 gttgtgctga ttgaggattc tgattttgtt gatcaggggt tgtatttgat tgttgcgtat
     7981 tattgttagg attggtagtc gtactattat ttgtgcttgg agtggttgag ctagactgtg
     8041 aagttgaact atctgatgat gagcttgaac tttcagttga tgggggttgt tgtggagcag
     8101 gtgagctcca cgtagaacga gcaccatttt taaatacgaa ttctccattt ctgtagagcc
     8161 cctctggtat attccaatcc tctggattgc ttccttcaga caggtaggtc atcatagagc
     8221 ggtaaacttt ggcagcgacc gtaaggccat tgcctacaag tggtgtcaga cggttagaat
     8281 agcctgtcca tacagccatt gaatatttac gcgtatagcc agcaaatagt tcatcaggtg
     8341 ctacaaattg agaggtcttg atgtggtttt caatttcctc gtctgtatag ttagaggttc
     8401 ctgttttacc agcctgaggg agccaagcaa gataggcatt tcgtccagtt ccataactca
     8461 agactgtttt catcatgtcg gtcatcatat aggctgtcgt ttccttcatg gcacgagttc
     8521 cgacattaga gaactctttt tcactcccat cactaaagac gactttatgg atatacattg
     8581 gtttatagta agttccacca tttgcaaagg cagcgtaagc agcagccatc ttttcactac
     8641 ttgctccata ttttttgtct gattcggttg tgttacttga aatggcattt gagtagtgaa
     8701 tacttgggta gtcgattccg agaccattta ggaaagtctt ggcgcggttg agtccgacct
     8761 tgtttagagt ttccacggct gggacgtttc gcgattgttg cagggcgtat tgcaaggtga
     8821 tgttgccaaa gtagccccta tcccagttat aaacaggagt atttgtccca gggtagttat
     8881 agggctcatc gtgaacgata gtagcagttg aatcgtagac accgtactcc aaggcaggag
     8941 catagtctgt gatcggtttc atagttgatc cccagtcgcg gtttgtttct actgcttggt
     9001 taattccgaa ggaaacatta cttgactgat ggcgtgctcc tagctgggca atgactttac
     9061 cgttagaaac atcaacaatg gtagaagcga cttgcaattc atcgtctgga taggcaacgt
     9121 attcgtctgt attgtaaata tcccacagat gtttttgagc ttcttggtct acatttgtgt
     9181 agacatccat cccagttgtg agcaggttat agcctgtttc ttcttcaact tgattgatga
     9241 cttccttgag gtaattatcc atgtaagcag ggtaattact tgctgatttg agactttgta
     9301 gtccatcagt aattggtgta ttgactgctt tctcatactg ttcagcagag atgtagcctt
     9361 gatttttcat ttcagataag accaagtttc ggcggtcttg ggctgcttct ggatgtgaat
     9421 aggggtcata ttggtttggt gcctgaggca ttccagccag caaggctaac tgaggtaaac
     9481 ttaaattatt gaggtcttta ccatagtagt tttgagctgc tgtctgcatt ccatagttcc
     9541 cattagacat gtagacctta tttatatagt aggtcaagat ttcttgcttg gttgcttttt
     9601 gttctaactg aatcgctaac caagcttcct gagccttacg agaaatagtc tggtcggaag
     9661 tcgaagttga aaagtaagtc aacttaatca actgttgagt gagagttgat ccaccttgga
     9721 gggaattgct ttgcagattg cgcaagaaag ctcccaggat acggatggta tcaatccccc
     9781 tgtggtcgaa gaagcgatgg tcttcgatag aaacgattgc cttaaccaaa tctgtgggaa
     9841 tatcattagc ttgggcattg acgcggcgtt cagaacccaa gtcagcaatg agttgatttt
     9901 tattgtcgta gattttacta gaagttgttg caactagttt actctcggat aggctaggag
     9961 ccttgctaac gtagtagaaa aaaactcctc cgcctaagac aatggctgcg ataaccaagc
    10021 ttaagaagct aatgctcaga tacttgatta ggcgcagaat cgttggtttg ttcatcttgt
    10081 tttaccacct aataaatgtt ctttgataac attgagataa ggaatttgag ggaaggcacc
    10141 agccttgatt tcatatccat attctcgaat atattcaagt ggcattgatt tttgtctctt
    10201 atcttgatga tagaagcgaa tcaaatcgaa tgccggcaat aagtaggttt cttgctgaga
    10261 agaaaagtga agaaggacaa agcagattcc ttgttgggca aggacttgtt ccatatgctg
    10321 aatctgatgt ggatgaaaat ttttcatcgg aatcgcacgt ttttgttttg tttccttgac
    10381 ttcaaagtcg atgtaatatc cattataaac gccagaatag tccgtcgttg aagcttgtcg
    10441 aaaataggct tcaacaatct tggcacgact tcgttgtgga tagtccactt gtacgatttg
    10501 aataggagtt ggtttcttat gtataacagc caagccctga gacaaatagt agtcgttggt
    10561 agcattgatc atcttttcaa aagacattcc tcgatttgcg aaatttttgg gttgagaaag
    10621 agatgtttgt cttttttgtg atgaaacttt atgtggatag ttgaccataa ttctccttat
    10681 tggtacaata acatcacttt attataccat aatttgcaca gaaagggtta aaaatggcta
    10741 cagctttggt tttaggctat tctgcttttg atttgggttt attttctgat aaggatcctc
    10801 gtcttaaatt gattaaaaaa gcgatacgta aagatttaga ggctatggca gcagatgggg
    10861 tgtcttggct tgtgtttaca gggagtttgg gttttgaata ttgggtttta gaggttgctc
    10921 aggagatgaa aaccgaatac ggtttccagt tggccaccat ttttgctttt gaaacccatg
    10981 gggaaaattg gaatgaaggc aatcagatga aactgagtcg ctttaagcag gtagactttg
    11041 tcaaatatgc ttatcctcgc tatgaacaca aggggcagtt aagagattac cagcagtttt
    11101 tgctggaaaa cacgactagt tcctatcttt tttatgatga agaaaatgaa acaaaactag
    11161 cttattttta ccaaaagatg aaaaatcaag aggactattt tataaagaga ttaacatttg
    11221 atgaattaaa tgaacttgct gaaaattttt ccgaaaattg aagctttgac cttgattttt
    11281 gtttgccttt ttttatataa taatactagc aagcgagaat ggagagagac atggcaagta
    11341 ttattttttc agcgaaagat atttttgaac aagagtttgg acgtgaagtc cgtggctata
    11401 ataaagtaga agttgacgag tttttagacg atgtcatcaa ggactatgaa acctatgctg
    11461 ccttggtcaa gtcacttcgt caggaaattg cggatttgaa ggaagaatta actcgtaaac
    11521 cgaaaccttc accagttcaa gcagaacccc ttgaagcggc aattacaagt tctatgacga
    11581 attttgatat tttgaaacgc ctgaatagat tggaaaaaga agtttttggt aaacaaattt
    11641 tagataactc agatttttaa gtagttattt gagatgtgca atttttggat aatcgcgtga
    11701 ggagaattgc ttctcatgag gaaagtccat gctagcacag gctgtgatgc ctgtagtgtt
    11761 tgtgctaggc gaaaccataa gcctagggac gagaaatcgt tacggcagtt gaaatggcta
    11821 agtccttgga taggccagag taggcttgaa agtgccacag tgacggagtc tttctggaaa
    11881 cagagagagt ggaacgcggt aaacccctca agctagcaac ccaaattttg gtcggggcat
    11941 ggagtacgcg gaaacgaacg tagtattctg actgctatca gctagagctg ttagtggtag
    12001 acagatgatt atcgaaggaa gtggtcctag tcacttctgg aacaaaacat ggcttataga
    12061 aaattgcata taggttgggg ctgagaaatt ttctcaacct cattttttaa agtggacata
    12121 tagaaaggtc ttgcaagact gtaacatgaa aaaagaattt aatttaattg caactgtggc
    12181 agcagggctt gaggctgtcg ttggtcgtga agtgcgagag ttgggctacg attgtcaggt
    12241 tgaaaatgga cgtgttcgtt ttcaaggaga cgtgagagct attatcgaaa ccaacctttg
    12301 gcttcgggca gcagatcgta tcaaaattat cgtaggaacg ttcccagcta agacttttga
    12361 agagctattt cagggagttt tcgctttaga ttgggaaaat tatttaccac ttggagctcg
    12421 gttcccgatt tcaaaagcta aatgtgttaa gtccaaactt cacaatgagc ccagtgttca
    12481 ggctatttct aagaaagctg ttgtcaagaa attgcagaaa cactatgctc gcccagaagg
    12541 ggttcctctg atggagaatg gcccagagtt taagattgag gtctctattc tcaaagatgt
    12601 ggcaactgtc atgattgata cgaccgggtc tagcctcttt aaacgtggtt atcgtaccga
    12661 aaaaggtggc gctcctatca aggaaaatat ggcagcagcc attttacaac tttctaactg
    12721 gtatccagac aagcctttga ttgatccgac ctgtggttcg gggactttct gtattgaggc
    12781 agttatgatt gctagaaaga tggcgccagg tcttcgtcgc tcttttgcat ttgaggaatg
    12841 gaactggatc agcgatcgct tgattcaaga agtgcgcaca gaagcggcta aaaaagtaga
    12901 acgtgagctt gagttggata tcatgggctg tgatattgat gctcgcatgg tggaaattgc
    12961 taaggccaat gctcaggcag ctggtgttgc aggagacatt acttttaagc agatgcgcgt
    13021 gcaggattta cgttccgata aaatcaatgg agtaatcatt tccaatccgc cttatggtga
    13081 acgtttgtca gatgatgcag gggtgaccaa gctctatgct gagatggggc aagtatttgc
    13141 accgctgaaa acttggagca aatttatcct gactagtgat gaagcttttg aaagcaagta
    13201 tggtagccaa gcagataaga agcgtaagtt atacaacgga accttgaaag tggatctata
    13261 tcaatatttt ggtcagcgtg tcaaacggca agaggtaaaa tagaaaggga tactcatgag
    13321 taaaaaaaga cgaaatcgtc ataaaaaaga aggtcaagaa ccgcaatttg attttgatga
    13381 agcaaaagag ctaacagttg gtcaagctat tcgtaaaaat gaagaagtgg aagcaggagt
    13441 cttgcctgag gattccattt tggacaagta tgttaagcaa cacagagatg aaattgaggc
    13501 ggataagttt gcgactcgtc aatacaaaaa agaggagttc gttgaaactc agagtctgga
    13561 tgatttaatt caagagatgc gtgaggctgt agagaagtca gaagcttctt cggaggaagt
    13621 tccatcttct gaagacatct tactaccctt gcctctggac gatgaggagc aaggcttgga
    13681 tcctctattg ctagatgatg aaaatccaac agaaatgact gaagaagtgg aagaggagca
    13741 aaacctttct cgtctggatc aagaggactc agaaaagaaa agtaaaaaag gctttatttt
    13801 gaccgttttg gcgcttgtat cagtaattat ttgtgtcagt gcttattatg tctaccgtca
    13861 agtggctcgt tcgaccaagg aaattgaaac ttctcaatca actacagcca atcaatcaga
    13921 tgtggatgat tttaatacac tttatgacgc cttttacaca gatagcaata aaacggcttt
    13981 gaaaaatagc cagtttgata aactgagtca actcaaaacc ttgcttgata aactggaagg
    14041 tagtcgtgaa catacgcttg ccaaatctaa atatgatagt ctagcaacgc aaatcaaggc
    14101 tattcaagat gtcaatgcac aatttgaaaa accagctatt gtggatggtg tgttggatac
    14161 caatgccaaa gccaaatcgg atgctaaatt tacggatatt aaaactggaa atacggagct
    14221 tgataaagtg ctagataagg ctatcagtct tggtaagagc cagcaaacaa gtacttctag
    14281 ctcaagttca agtcaaacta gcagctcaag ctctagtcaa gcaagttcaa atacgactag
    14341 tgagccaaaa ccaagtagtt caaatgagac tagaagtagt cgcagtgaag tcaatatggg
    14401 tctctcgagt gcaggggttg ctgttcaaag aagtgccagt cgtgttgcct ataatcagtc
    14461 tgctattgat gatagtaata actctgcctg ggattttgcg gatggtgtct tggaacaaat
    14521 tctagcgact tcacgttcac gtggctatat cactggagac caatatatcc ttgaacgtgt
    14581 caatatcgtt aacggcaatg gttattacaa cctctataag ccagatggaa cctatctctt
    14641 tacccttaac tgtaagacag gctactttgt cggaaatggc gctggtcatg cggatgactt
    14701 ggactactaa gcagtcgtta caaaattctt tcttttcaaa agtaaaaatg ataaaataaa
    14761 acaaatgaaa caagaggagt gtcaaatgac aaaagctaac tttggtgtcg taggtatggc
    14821 cgtaatgggt cgtaaccttg cccttaatat tgaatcacgt ggttacacag ttgctatcta
    14881 caaccgtagt aaagaaaaaa cggaagatgt gattgcttgc catcctgaaa agaactttgt
    14941 accaagctat gacgttgaaa gttttgtaaa ctcaatcgaa aaacctcgtc gtatcatgct
    15001 gatggttcaa gctggacctg gtacagatgc tactatccaa gcccttcttc cacaccttga
    15061 caagggtgat atcttgattg acggtggaaa tactttctac aaagatacca tccgtcgtaa
    15121 tgaagaattg gcaaactcag gtatcaactt tatcggtact ggagtttctg gtggtgaaaa
    15181 aggtgccctt gaaggtcctt ctatcatgcc tggtggacaa aaagaggcct acgaattggt
    15241 tgcggatgtt cttgaagaaa tctcagctaa agcaccagaa gatggcaagc catgtgtgac
    15301 ttacatcggt cctgatggag ctggtcacta tgtgaaaatg gttcacaatg gtattgagta
    15361 cggtgatatg caattgatcg cagaaagcta tgacttgatg caacacttgc taggcctttc
    15421 tgcagaggat atggctgaaa tctttactga gtggaacaag ggtgaattag acagctactt
    15481 gatcgaaatc acagctgata tcttgagccg taaagacgat gaaggccaag atggaccaat
    15541 cgtagactac atccttgatg ctgcaggtaa caagggaact ggtaaatgga cgagccaatc
    15601 atctcttgac cttggtgtac cattgtcact gattactgag tcagtgtttg cacgctacat
    15661 ttcaacttac aaggaagaac gtgtacatgc tagcaaggtg cttccaaaac cagctgcctt
    15721 caactttgaa ggagacaagg ctgaattgat tgaaaaaatc cgtcaagccc tttacttctc
    15781 aaaaatcatt tcatacgcac aaggatttgc tcaattgcgt gtagcctcta aagaaaacaa
    15841 ctggaacttg ccatttgcag atatcgcatc tatctggcgt gatggctgta tcatccgttc
    15901 tcgtttcttg caaaagatta cagatgctta caaccgcgat gcagatcttg ccaaccttct
    15961 tttggacgag tacttcttgg atgttactgc taagtatcaa caagcagtgc gtgatatcgt
    16021 agctcttgcg gttcaagctg gtgtgccagt gccaactttc tcagcagcta ttacttactt
    16081 tgatagctac cgttcagctg accttccagc taacttgatc caagcacaac gtgactactt
    16141 tggtgctcac acttaccaac gtaaagacaa agaaggaacc ttccactact cttggtatga
    16201 cgaaaaataa gtaggtcagc catggggaaa cggattttat tacttgagaa agaacgaaat
    16261 ctagctcatt ttttaagttt ggaactccag aaagagcagt atcgggttga tctggtagag
    16321 gaggggcaaa aagccctctc catggctctt cagacagact atgatttgat gttattgaac
    16381 gttaatctgg gagatatgat ggctcaggat tttgcagaaa aattgagtcg aactaaacct
    16441 gcctcagtca tcatgatttt agatcattgg gaagacttgc aagaagagct ggaagttgtt
    16501 cagcgttttg cagtttcata catttataag ccagtcctta tcgaaaatct ggtagcgcgt
    16561 atttcggcga tcttccgagg tcgggacttc attgatcaac actgcagtct gatgaaagtt
    16621 ccaaggacct accgcaatct taggatagat gttgaacatc acacggttta tcgtggtgaa
    16681 gagatgattg ctctgacccg ccgtgagtat gaccttttgg cgacacttat gggaagcaag
    16741 aaagtattga ctcgtgagca attgttggaa agtgtttgga agtatgaaag tgcgaccgag
    16801 acaaatatcg tagatgtcta tatccgctat ctacggagca agcttgatgt taaaggccaa
    16861 aaaagctaca ttaaaaccgt gcgtggtgtt ggatatacca tgcaagaata gataagcagt
    16921 tgcagttgtg taactgcttt tttgaggagt ttttatatat tgacatgcag tcgggtcttt
    16981 gctacaatcg ttttaggagg atatatagat gaaacttttg aaaaaaatga tgcaagttct
    17041 actagcagtc tttttctttg gtttgctagc tacaaatacg gtatttgcga ataccacagg
    17101 tggccgattt gttgataagg ataatagaaa atattatgta aaagatgatc ataaagcaat
    17161 ctattggcat aaaatagacg gtaaaactta ctattttggt gatattggag agatggttgt
    17221 cggttggcaa tacttagaaa ttcctggaac aggttatcgt gataatttat tcgataacca
    17281 accagttaat gaaattggcc ttcaggagaa gtggtactat tttggacaag atggtgcttt
    17341 gctagaacaa acagataaac aagtactaga ggcaaaaacg tctgaaaata caggaaaagt
    17401 atacggtgaa caatatcctc tatctgctga aaagagaact tattattttg ataataatta
    17461 tgctgtaaag acaggctgga tttatgaaga cggcaattgg tattatttaa ataagctagg
    17521 aaattttggc gatgattctt acaatccact accaattagt gaagttgcta agggttggac
    17581 tcaagatttt catgttacta ttgacattga tagaagcaaa cctgctccat ggtactacct
    17641 agacccagaa actggcatta tgcgaacagg atggcaatat ctaggtaata actggtacta
    17701 cctccgttca tcaggagcaa tggccactgg ctggtatcag gaaggtacca cttggtatta
    17761 tttagaccag ccaaatggcg atatgaaaac aggttggcaa aaccttggga acaaatggta
    17821 ctatctccgt tcatcaggag ctatggcaac tggttggtat caagatggtt caacttggta
    17881 ctacctaaat gcaggtaatg gagacatgaa gacaggttgg ttccaggtca atggcaactg
    17941 gtactatgct tatagctcag gtgctttggc agtgaatacg accgtagatg gctattctgt
    18001 caactataat ggcgaatggg ttcggtaatg acagggcgct tataattata ttagaacact
    18061 cgcttaatca aagaagtgac tttgttgtac ttgacctgac gattggggag attaaaagca
    18121 tgtgaaatct acacatgctt tttcgttagt tatgagtgtt gaacttgact aaccattgac
    18181 aaaagataag agcaattaaa ataagataca aaaatatcaa tgctaactgc accgaaacgc
    18241 ccgatgctat ggatagggct aatagggaga gcagggacgg ggcgagaatg tccactgtgc
    18301 tcagagcaga gcccaccgtc cccatcttgt cactggggat ataggcaaag acagctgctt
    18361 gtaggcgagg gctgagaatg ccgataatcg tagaactgat gaaactggtc atgaaaatta
    18421 cgatataggc ttgacaaagg atactagtta ttagagccaa tagggaaatc tcacagaaaa
    18481 ccaagaggtg cgtgaaacgg atatttttaa atagattact gctggtcata ttgccaagga
    18541 tagctccaca agacatgatg atggagagca gggcgaggag ttgcccaatg ctcagttgtg
    18601 ctagtgtctg ttggatgaag cggagggcaa tcagccgagg ggacacatcc aagatggcaa
    18661 tcatactggt cgtcagaaac agtagtatga cggtatcttt taacttcagt agcacagcca
    18721 gcgactgttt aagatgttga aaatatttct taaaactcag tgctgtatgt gacatttcaa
    18781 tccttttttc aacctcatac aaggtatgtc gaataacata caggcccaaa aaggcaatga
    18841 caaaagtcag agtgttgata agggaaatag tttgaatact tataacattg ataaggaatg
    18901 cgccagccag attggcgaca atgcggacaa ccctcatcag agactgcctg aaccccatgg
    18961 catcatgcag gtcgtcctta attacactga tgtagagggc gttcatcatg taggcagaca
    19021 ggtagctcaa ggtgtcagag atgaggttga tgatgacaat cataatgact gaaactaatg
    19081 aaaagggcga caagacgaga aatactgtca aaatagcgta gagcaggatt ttgattttgg
    19141 caatacagag tgcgtgtttg actctatttt cttgaaaatc tcctagaatc ccgagaaaga
    19201 gttgcgatag taggggaacc atctctgaaa tggaaatcag taaaatcgct agcggagcga
    19261 aattgtactg agccacataa ttgataatgg cgaggtagaa aatactgtcg ccgaatgatg
    19321 aaaaacagct gtttagcagc aactgtctat atatgttgtt tgtccaaaat aatttcatac
    19381 atttctcctt atgtctgcac atcgaatggg aatttattat ttaatagaca ccaatatacc
    19441 cccatgcttc ctattccgaa gtcaaacaaa tctgctttac cactatctcc ttgaaacatc
    19501 agtaaaccgt gatcatctcg ttcagaacat gctaaaatta cctgttggat tttttcatca
    19561 gtaatttgtt ttgattgtag acagtggttt gtagtaagct agttattccg tggcaatatc
    19621 ctgtcatcat ttttagatga tggttaaaaa caaattcttg atatttacta ataatatctt
    19681 tgtttccgtc acaatcgtac atacaaagat ataagattat tccggaaatt cctttgcacc
    19741 aagaaagttg taaatttcct aaattttcag tattagaagt aactttttct aataattttt
    19801 ttaattcagt atggaatgta tggagatcat tatagaacat agaaggttct aagactttag
    19861 aataggcaaa taaagcatat gcaattccac aatatccatg agcaaagcta tagtctaaaa
    19921 tgctttcttt ggctgtatct ctttgtagga aataatgata aatttcccca tatactattg
    19981 tggatgaaag ttttaagagt attgtcattg gtaacttgat agtattttat taatgataat
    20041 aggacaccag attttcccaa tgcaaagtct atttcctcta gagtatcata attctctatt
    20101 aatttcttag cggtgacgtt tgctaattgt agatagtatt gatttttact gatagaaaat
    20161 aaatgtagga gtaactatag atagcctgca ccaccaaata gcagtgagta ttgatattca
    20221 tatgtgtgtg acgttctaat tgtcactgcc ttcttgatga tagagagtat tttagaatcc
    20281 agttctgggt ggtacaattt atttagagga aacagtagtc cagctattcc gtgttggaat
    20341 gataaattac ttacgaaatt tccaaattct gttgaagaag tgatccttcc ttcagaattt
    20401 acagttttat ctagtaaaaa tcgtagaaca ctattacatt ctgttttgta atcatattta
    20461 tgttcctcta tttttttaat tttgactaaa ttatttgttt gacttaaatt tagtagacat
    20521 tgtaaccaaa atagttgctc atctgtgagc tgaccttgag tatgtgatag ttctagtaat
    20581 tgaataggat cctttagtta gattcaatca atctataaca caacaacata ataatacttt
    20641 taggataact tgtcaaata
//
LOCUS       DAVBOG010000038        20107 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.038, whole genome shotgun sequence.
ACCESSION   DAVBOG010000038 DAVBOG010000000
VERSION     DAVBOG010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 20107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20107
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.038"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            638..952
                     /locus_tag="VQ865_001526"
     CDS             638..952
                     /locus_tag="VQ865_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3135850.1"
                     /translation="MELKFVIPNMEKTFGNLEFAGEDKVVQRRINGRLTVLSRSYNLY
                     SDVQRADDIVVVLPAEAGEKHFGFEERVKLVNPRITAEGYKIGTRGFTNYLLHADDMI
                     KE"
     gene            968..1354
                     /locus_tag="VQ865_001527"
     CDS             968..1354
                     /locus_tag="VQ865_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HET3135851.1"
                     /translation="MMRLANGIVLDKDTTFGELKFSALRREVRIQNEDGSVSDEIKER
                     TYDLKSKGQGRMIQVSIPASVPLKEFDYNARVELINPIADTVATATYQGADVDWYIKA
                     DDIVLTKDSSSFKAQPQAKKEPTQDK"
     gene            1383..2768
                     /locus_tag="VQ865_001528"
     CDS             1383..2768
                     /locus_tag="VQ865_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HET3135852.1"
                     /translation="MKQRGKRIRPSGKDLVFHFTIASLLPVFLLVVGLFHVKTIQQIN
                     WQDFNLSQADKIDIPYLIISFSVAILICLLVAFVFKRVRYDTVKQLYHRQKLAKMILE
                     NKWYESEQVKTEGFFKDSAGRTKEKITYFPKMYYRLKNGLIQIRVEITLGKYQDQLLH
                     LEKKLESDLYCELTDKELKDSYVEYTLLYDTIASRISIDEVEAKDGKLRLMKNVWWEY
                     DKLPHMLIAGGTGGGKTYFILTLIEALLHTDSKLYILDPKNADLADLGSVMANVYYRK
                     EDLLSCIETFYEEMMKRSEEMKQMKNYKTGKNYAYLGLPAHFLIFDEYVAFMEMLGTK
                     ENTAVMNKLKQIVMLGRQAGFFLILACQRPDAKYLGDGIRDQFNFRVALGRMSEMGYG
                     MMFGSDVQKDFFLKRIKGRGYVDVGTSVISEFYTPLVPKGYDFLEEIKKLSNSRQSTQ
                     ATCEAEVAGVD"
     gene            2771..2923
                     /locus_tag="VQ865_001529"
     CDS             2771..2923
                     /locus_tag="VQ865_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000879507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3135853.1"
                     /translation="MLAGVAIATPALNPPYLTGGYKSTGNSQKNIRKSFGYKGFTKFQ
                     RMSNGL"
     gene            2946..4151
                     /locus_tag="VQ865_001530"
     CDS             2946..4151
                     /locus_tag="VQ865_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000398284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HET3135854.1"
                     /translation="MEGFLLNEQTWLQHLKEKRLAYGLSQNRLAVATGITRQYLSDIE
                     TGKVKPSEDLQQSLWEALERFNPDAPLEMLFDYVRIRFPTTDVQQVVENILQLKLSYF
                     LHEDYGFYSYSEHYALGDIFVLCSHELDKGVLVELKGRGCRQFESYLLAQQRSWYEFF
                     MDVLVAGGVMKRLDLAINDKTGILNIPVLTEKCQQEECISVFRSFKSYRSGELVRKEE
                     KECMGNTLYIGSLQSEVYFCIYEKDYEQYKKNDIPIEDAEVKNRFEIRLKNERAYYAV
                     RDLLVYDNPEHTAFKIINRYIRFVDKDDSKPRSDWKLNEEWAWFIGNNRERLKLTTKP
                     EPYSFQRTLNWLSHQVAPTLKVAIKLDEINQTQVVKDILDHAKLTDRHKQILKQQSVK
                     EQDVITTKK"
     gene            4194..4415
                     /locus_tag="VQ865_001531"
     CDS             4194..4415
                     /locus_tag="VQ865_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135855.1"
                     /translation="MNFGQNLYNWFLSNAQSLVLLAIVVIGLYLGFKREFSKLIGFLI
                     IAIIAVGLVFNAAGVKDILLELFNRIIGA"
     gene            4532..5029
                     /locus_tag="VQ865_001532"
     CDS             4532..5029
                     /locus_tag="VQ865_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000342537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HET3135856.1"
                     /translation="MDDMQVYIANLGKYNEGELVGAWFTFPIDFEEVKEKIGLNDEYE
                     EYAIHDYELPFTVDEYTSIGELNRLWEMVSELPEELQSELSALLTHFSSIEELSEHQE
                     DIIIHSDCDDMYDVARYYIEETGALGEVPASLQNYIDYQAYGRDLDLSGTFISTNHGI
                     FEIVY"
     gene            5004..5510
                     /locus_tag="VQ865_001533"
     CDS             5004..5510
                     /locus_tag="VQ865_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016897981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3135857.1"
                     /translation="MGFLKSSIKSVGTLLLADFLFYGVAQSATPIFYERIDYMKKIRS
                     YTSIWSVEKVLYSINDFRLPFPITFTQMTWFVVSLFAVMILGNLPPLSMIEGAFLKYF
                     GIPVAFTWFMSTKTFDGKKPYGFLKSVIAYALRPKLTYAEKKVTLGRNQPQEAITAVR
                     SEFYGISN"
     gene            5494..7941
                     /locus_tag="VQ865_001534"
     CDS             5494..7941
                     /locus_tag="VQ865_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HET3135858.1"
                     /translation="MAYPIKYIENNLVWNKDGECYAYYELVPYNYSFLSPEQKIQVHD
                     SFRQLIAQNRDGKIHALQISTESSIRSAQERSKNEVTGKLKAVAYDKIDQQTDALISM
                     IGENQVNYRFFIGFKLLLNDQEFSMKSLTVEAKNALSDFVYDVNHKLMGDFVSMSNDE
                     ILRFQKMEKLLENKISRRFKIRRLDKDDFGYLIEHLYGQTGTAYEEYEYHLSKKKLDN
                     ETLIKYYDLIKPTRCLVEEKQRYLKIQQEDETVYVAYFTINSIVGELDFPSSEIFYYQ
                     QQQFTFPIDTSMNVEIVANRKALSTVRNKKKELKDLDNHAWQSDNETSSNVAEALESV
                     NELETNLDQSKESMYKLSYVVRVSANDLDELKRRCNEVKDFYDDLSVKLVRPFGDMLG
                     LHEEFLPASKRYMNDYIQYVTSDFLDGLGFGATQMLGENEGIYVGYSLDTGRNVYLKP
                     ALASQGVKGSVTNALASAFVGSLGGGKSFANNLIVYYAVLYGAQAVIVDPKAERGRWK
                     ETLPEISHEINIVTLTSDEKNKGLLDPYVIMKNPKDSESLAIDILTFLTGISSRDGER
                     FPILRKAIRAVTNSEVRGLMKVIEELRVENTPLSTSIADHIESFTDYDFAHLLFSNGY
                     VEQSISLEKQLNIIQVADLVLPDKETSFEEYTTMELLSVAMLIVISTFALDFIHTDRS
                     IFKIVDLDEAWSFLQVAQGKTLSMKLVRAGRAMNAGVYFVTQNTDDLLDEKLKNNLGL
                     KFAFRSTDLNEIKKTLAFFGVDPEDENNQKRLRDLENGQCLISDLYGRVGVIQFHPVF
                     EELLHAFDTRPPVRKEV"
     gene            7944..10121
                     /locus_tag="VQ865_001535"
     CDS             7944..10121
                     /locus_tag="VQ865_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3135859.1"
                     /translation="MKPSIVNRIKSNWTLKRLGKVAMTVAFTLVIAIFLLAMLGTVVQ
                     AAGLVDDTVNVANEYSRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNF
                     IWTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLL
                     LLILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDI
                     SNASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRV
                     ESLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFV
                     FLLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLII
                     TTAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRV
                     MRKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGK
                     EKSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRD
                     LTSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQY
                     HDEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTT
                     ADRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            10118..11119
                     /locus_tag="VQ865_001536"
     CDS             10118..11119
                     /locus_tag="VQ865_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3135860.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            11116..12051
                     /locus_tag="VQ865_001537"
     CDS             11116..12051
                     /locus_tag="VQ865_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3135861.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            12296..12412
                     /locus_tag="VQ865_001538"
     CDS             12296..12412
                     /locus_tag="VQ865_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3135862.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ865_001539"
     CDS             12428..14347
                     /gene="tet(M)"
                     /locus_tag="VQ865_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3135863.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            14466..14633
                     /locus_tag="VQ865_001540"
     CDS             14466..14633
                     /locus_tag="VQ865_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3135864.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(14693..15046)
                     /locus_tag="VQ865_001541"
     CDS             complement(14693..15046)
                     /locus_tag="VQ865_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3135865.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            15551..15973
                     /locus_tag="VQ865_001542"
     CDS             15551..15973
                     /locus_tag="VQ865_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3135866.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            15970..16200
                     /locus_tag="VQ865_001543"
     CDS             15970..16200
                     /locus_tag="VQ865_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3135867.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            16661..16864
                     /locus_tag="VQ865_001544"
     CDS             16661..16864
                     /locus_tag="VQ865_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3135868.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            16946..18163
                     /locus_tag="VQ865_001545"
     CDS             16946..18163
                     /locus_tag="VQ865_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3135869.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
     gene            complement(18325..18927)
                     /locus_tag="VQ865_001546"
     CDS             complement(18325..18927)
                     /locus_tag="VQ865_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135870.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKFLCIGELTILQIIYGASLIS
                     FLWMYGQRKQVAKVNMETRIKWIGIGFVSLLIISLYFSLIHAQESTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALAHHPGTILAWCLYV
                     SLGMFLGMVRYKSDLWGSMGLHLVWNLLVYSLLLFNKNKV"
     gene            complement(18930..19163)
                     /locus_tag="VQ865_001547"
     CDS             complement(18930..19163)
                     /locus_tag="VQ865_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3135871.1"
                     /translation="MAERFWENLSIILAERNISWIELTRKMFAGEFHYPSELNRLYQK
                     IRHYKMEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            complement(19176..19556)
                     /locus_tag="VQ865_001548"
     CDS             complement(19176..19556)
                     /locus_tag="VQ865_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135872.1"
                     /translation="MIDLYLSKNNHRNQLLLEFFQNYGIEVSCHSISEMTRDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELTIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSN"
     gene            complement(19549..19998)
                     /locus_tag="VQ865_001549"
     CDS             complement(19549..19998)
                     /locus_tag="VQ865_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135873.1"
                     /translation="MKALNKESILYCDELETELHDAEMMQLDEQIFLMPNYPCEFEVT
                     FLDYYHKKHNYPLFYESYLQNIMEFLESQDIKNGADAFIDDNHNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKSINFSNLLDSLIVSEYQMEPNLWEVSHD"
     gene            complement(19982..>20107)
                     /locus_tag="VQ865_001550"
     CDS             complement(19982..>20107)
                     /locus_tag="VQ865_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3135874.1"
                     /translation="ARKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESAK"
BASE COUNT         6584 a         3637 c         4063 g         5823 t
ORIGIN      
        1 agtctggtaa cgataaactc cgtgtctgtt agaaaattct cacacacgtc ttgtgccagt
       61 tgcccttcac agggaaatac tctcagtccc tacttacaca ggcacgctaa tcaagacgga
      121 gtggattcaa ttttcaaaga acaggtagct ttattataga gaagagtagt tgaaattttt
      181 atcacatttt ttatttttct gtagagctaa attcatacta aacaaagatt ttgaaataaa
      241 agactaacat tgttacataa cgttagcatt tcatttccct aaaataagct aattttgtct
      301 aaaaaatagc ataaaaatct agttatccgc ataaaaactg gacttatcac actttatcaa
      361 ggtcaaaacc actcaattta ctactaattt actacttatg aatgagcttt gatacgacga
      421 tttatccttg aaaagtgaag atataaagat acttccaata aaatttgaat atttaatagg
      481 tagacacttc aaaaaatgag gtgtctattt ttttacccga ttttgaaagg aagtgaactt
      541 atgaaaacaa aaaatcaaga atcaaaaggt cgttccccac tctttaagac catcaaacat
      601 tcattcagcc aataaaaaag aaaggatagg taaaaatatg gaacttaaat ttgtgattcc
      661 caacatggaa aaaacattcg gcaatttaga atttgctggc gaggataaag tcgttcagcg
      721 aagaatcaac ggacggctaa ctgtcttatc aagaagctat aatctctatt ctgatgttca
      781 aagagcagat gatattgtgg tggtgcttcc tgctgaagct ggcgaaaaac atttcggctt
      841 tgaggaacgt gtgaagttag tcaatccacg tattaccgca gagggctaca aaatcggcac
      901 tcgtggtttt acaaattacc ttttacatgc tgacgacatg ataaaagaat aaagaaagag
      961 aggaaaaatg atgagattag caaatggcat tgtattagat aaagacacga cttttggaga
     1021 attgaaattc tctgctctac gtcgtgaagt gagaatccaa aatgaagacg ggtcggtttc
     1081 agatgaaatc aaggaacgta cctatgactt aaaatccaaa ggacaaggac gcatgattca
     1141 agtaagtatt cctgccagcg tgcctttgaa agagtttgat tataacgcac gggtggaact
     1201 tatcaatccc attgcggaca ccgttgctac tgccacctat caaggagcag atgttgactg
     1261 gtatatcaag gcagacgata ttgtgctgac aaaggattct agttcattca aagctcaacc
     1321 acaagcaaag aaagaaccga cacaagacaa atagtcgcta ggtagaaagg agactttttc
     1381 gcatgaaaca gcgtggtaaa aggattcgcc catctggtaa agatttagtc tttcatttta
     1441 cgatagcgtc actcctgcct gttttcctgc tggttgtcgg actgtttcat gtgaagacaa
     1501 tccagcagat caactggcag gattttaacc tatcacaagc agataagatt gacattccct
     1561 atttaattat cagtttcagt gtcgcaattc ttatctgctt gctggtagcg tttgtattca
     1621 aacgggttcg ctatgatacg gttaaacaac tttaccaccg tcaaaaactg gcaaagatga
     1681 tacttgaaaa caagtggtat gaatctgaac aggtcaaaac agagggtttc tttaaagata
     1741 gtgctggtcg tacaaaggaa aagataacct acttccctaa aatgtattat cgacttaaaa
     1801 atggcttgat acagatacgg gtggaaatca cgctgggaaa atatcaagac caactcttac
     1861 acttggaaaa gaaattagag agtgacttgt actgtgagct gacggataaa gagttaaagg
     1921 attcctatgt ggaatatact ttgctctatg acaccatagc cagtcgtatt tctattgatg
     1981 aagtagaagc taaagatggt aaacttcgct taatgaaaaa cgtatggtgg gaatatgata
     2041 agctccctca tatgttgatt gctggtggta caggtggcgg taaaacttac tttatactga
     2101 cactgattga agccttgctt catacagatt caaaactgta tattcttgac ccgaaaaatg
     2161 ctgaccttgc ggacttaggt tctgtgatgg caaatgtcta ctatagaaaa gaagacttgc
     2221 tttcttgcat tgaaacattc tatgaagaaa tgatgaaacg tagtgaggaa atgaagcaga
     2281 tgaagaacta taagactggc aaaaattatg cttacttagg tctcccggca cacttcttaa
     2341 tctttgatga atacgtcgct ttcatggaaa tgctgggaac aaaagaaaac accgcagtta
     2401 tgaataagct gaaacagatt gtcatgttag gtcgtcaagc tggcttcttt ctaatactgg
     2461 cttgtcaacg tccagacgca aaatatttag gcgacggaat ccgtgatcag tttaatttca
     2521 gagtggcttt aggtcgtatg tctgaaatgg gctatggcat gatgtttggc agtgacgtac
     2581 aaaaggattt cttcttaaag cgaatcaaag gtcgtggcta tgttgatgta ggaacaagtg
     2641 tcatatcaga gttttatact ccccttgtac caaaaggata tgatttcttg gaggaaatta
     2701 aaaagttatc caacagcaga cagtccacgc aggcgacgtg cgaagcggaa gtcgcaggtg
     2761 tggactgatc ttgctggctg gtgtggcaat agccacgcca gcacttaacc ccccgtatct
     2821 aacagggggg tacaaatcga caggaaacag tcaaaaaaac attagaaaat cctttggtta
     2881 caagggattt acaaaatttc agcgtatgtc aaatgggctt taaaagttga catacgcctt
     2941 tttgattgga gggattttta ctgaatgaac aaacttggtt acagcattta aaagaaaaac
     3001 gcttggctta tggactatct caaaaccgtt tagctgttgc gactggtatt acaaggcagt
     3061 atctaagcga tattgaaaca ggaaaagtca agccatcaga ggatttacag cagtcccttt
     3121 gggaagctct ggaacgcttc aatcccgacg ctccccttga aatgctgttt gattatgtaa
     3181 ggattcgctt tccgacaaca gacgtacagc aggtggtcga aaacatctta caactgaaac
     3241 tgtcctattt tcttcatgag gactatggtt tctattctta ttcagagcat tatgctttag
     3301 gcgacatatt cgtcctttgc tcccatgaac tggacaaagg agttctggtg gaattgaaag
     3361 gtcgtgggtg cagacaattt gaaagctatc ttctggcaca acaaagaagc tggtatgagt
     3421 tctttatgga cgttttggtg gctggcggtg tgatgaaacg ccttgacctt gccattaacg
     3481 ataagacagg gattttgaat atccctgtac tcactgaaaa gtgccaacag gaagaatgta
     3541 tctccgtctt ccgcagtttt aaaagctatc gcagtggcga actggtacgc aaagaggaaa
     3601 aggaatgtat gggaaacacc ctctatatcg gttcattaca aagtgaagtt tatttctgta
     3661 tctatgaaaa ggactacgag cagtacaaga aaaatgatat tcccattgaa gacgcagaag
     3721 taaaaaaccg ttttgagatt cgattgaaaa atgagcgtgc ctattatgca gtccgtgatt
     3781 tactcgtcta tgacaatcca gagcataccg cctttaaaat tatcaatcgg tatatccgtt
     3841 ttgtagataa agacgattcc aaacctcgtt ctgattggaa actgaatgaa gaatgggctt
     3901 ggtttattgg gaacaatcgt gaacgattaa aactaaccac aaaaccagag ccttactcct
     3961 tccaaaggac gctgaactgg ctatctcatc aagttgcccc gaccttaaag gttgcgatta
     4021 aacttgatga aatcaaccag acgcaggttg taaaagacat tctcgaccat gcgaaactga
     4081 cagaccgaca caagcagatt ttgaagcaac agtcagtaaa agaacaggac gtgataacaa
     4141 caaaaaaata actcaaatac aaattcattg aatatagaga ggagaacatt tttatgaatt
     4201 ttggacaaaa cctttataac tggtttctat caaacgctca atcactggtg cttttagcaa
     4261 tcgttgtgat tggcttgtat cttggcttca agcgtgagtt tagcaaactg attggctttt
     4321 taattattgc gattattgcg gttggcttag tcttcaacgc tgctggagta aaagacattt
     4381 tactagagct attcaatcgc attattggtg cttaaataaa accgttcttt tgtggaatat
     4441 aagtggtttt cttatgttcc gcaaaggaat ggtacaccaa acgaagtgcg gtagggattt
     4501 ttgaatctct acaaagaaag gacgtgaata tatggacgat atgcaagtct atattgcgaa
     4561 tttaggcaaa tacaatgagg gcgaattggt cggtgcgtgg tttacctttc ccattgactt
     4621 tgaggaagtc aaagagaaaa tcggcttgaa tgatgaatat gaggaatacg ccattcatga
     4681 ctacgagtta ccctttacgg ttgacgaata cacttccatt ggcgaactca atcgactatg
     4741 ggaaatggta tcggaattac ccgaagaatt acaatcggag ctatctgctc tgctcactca
     4801 tttttcaagc attgaagaac taagcgaaca tcaagaggat attatcattc attccgattg
     4861 tgatgatatg tatgacgtgg cacgctacta cattgaagaa acgggtgctt taggcgaagt
     4921 accagctagt cttcaaaact atattgatta tcaagcctat ggtcgggatt tagacctttc
     4981 aggaacgttt atctcaacca atcatgggat ttttgaaatc gtctattaaa tctgtcggta
     5041 cattactact ggcagatttt ctattttacg gggtggctca atcagctacc cctatttttt
     5101 atgaaaggat tgattacatg aagaaaatac gaagctatac cagtatctgg tctgtggaaa
     5161 aggtactgta ttctatcaat gattttagac ttccgtttcc cataaccttt acgcaaatga
     5221 catggtttgt cgtgtcactc tttgcagtga tgatacttgg caacttgccc cctctttcca
     5281 tgatagaggg agcatttctc aaatactttg ggattcctgt ggctttcaca tggtttatgt
     5341 ctacaaaaac ttttgatggt aaaaagcctt atggattttt gaagtctgtc attgcttatg
     5401 cactgcgacc aaagctgacc tatgcagaaa aaaaagtaac gcttggcaga aaccagccac
     5461 aagaagccat tacagcagtt aggagtgaat tttatggcat atccaattaa atacattgaa
     5521 aacaatctcg tctggaataa agacggggaa tgttatgctt actatgagct tgttccttac
     5581 aattactcat ttctaagtcc agaacagaaa atacaagtgc atgattcttt cagacagctt
     5641 atcgcacaaa atcgtgatgg caaaattcat gctttacaaa tcagtacaga atccagcata
     5701 cgttctgcac aagagcgttc caaaaatgaa gtcactggca agctcaaagc ggttgcctat
     5761 gacaaaatcg accaacagac agacgcttta atatccatga ttggcgaaaa tcaagtgaac
     5821 taccgtttct ttatcggctt taagttgctt ctcaacgatc aggagttttc tatgaaaagt
     5881 cttaccgttg aagcaaaaaa tgctttgtct gattttgtct atgatgtgaa ccataagctg
     5941 atgggcgatt ttgttagtat gagtaatgat gaaatcctgc gttttcagaa gatggaaaag
     6001 ctcttagaaa ataaaatctc tcgtcgtttc aaaatccgca ggttagataa ggacgacttc
     6061 ggctatctga ttgaacacct ttacggacag acaggcactg cctatgaaga gtatgagtac
     6121 catctatcaa agaaaaagct ggataatgaa acgctgatta aatactatga cttgattaag
     6181 cctactcgct gtttggtgga agaaaaacag cgatatttga aaatccagca ggaagatgaa
     6241 accgtctatg tagcttactt taccattaac agcattgtcg gagaactgga cttcccgtcc
     6301 tctgaaatct tctactacca gcaacagcaa tttacattcc cgattgatac gtcaatgaat
     6361 gtggaaattg tagcgaatcg taaagcccta tctactgtcc gcaataaaaa gaaagaactg
     6421 aaagacttgg ataaccacgc ttggcaaagt gataatgaaa ccagctccaa tgtggcggaa
     6481 gctctggaaa gtgtgaatga gctggaaacc aatttagacc aaagcaagga atctatgtac
     6541 aagctgtctt atgtggtaag ggtatcagca aatgatcttg acgaactcaa acgtcgttgt
     6601 aatgaagtga aagattttta tgacgattta agcgtaaaac tggtacgacc atttggggat
     6661 atgctcggct tacatgaaga atttttacct gccagcaagc gttatatgaa tgattatatt
     6721 caatacgtga cctctgattt cctcgatggt ttaggttttg gtgctactca aatgctgggg
     6781 gaaaatgagg ggatttatgt tggctacagc ttagatactg gacgcaatgt ctatctgaaa
     6841 cctgctcttg ccagtcaagg ggttaagggt tcagtaacca atgcgttagc gtcggctttt
     6901 gttggttcgc tgggtggtgg taaatccttt gcgaataacc ttatcgtcta ttatgcggtg
     6961 ctttatgggg cacaagcagt gattgtagac ccaaaagcag aacgtggcag atggaaagaa
     7021 accttgccag agatttccca tgaaatcaat atcgtcactc tgacttctga tgagaaaaac
     7081 aaaggcttac ttgaccctta tgtgattatg aaaaatccca aagattctga atcactggct
     7141 attgatattc tgacattcct tacggggatt tcctctcgtg atggggaacg cttcccaatc
     7201 cttagaaaag ccattcgtgc agtaaccaat agtgaagtac gagggttgat gaaagtgatt
     7261 gaggaattac gggttgagaa tacgccacta agtaccagta tagccgacca tatcgaaagt
     7321 tttacagact atgactttgc acatttatta ttcagtaatg gttatgtgga gcagtctatc
     7381 agcttagaaa aacaactgaa cattatacag gttgcggact tggtacttcc cgacaaggaa
     7441 acttcctttg aggaatatac cactatggag cttttatccg ttgctatgct gattgtcatt
     7501 agtacctttg ctttagactt tatccataca gaccgaagca ttttcaagat tgtagattta
     7561 gacgaagcat ggagcttttt acaggtagca caaggaaaaa cactatctat gaagctggtt
     7621 cgggctggtc gtgctatgaa cgctggggta tatttcgtga cccaaaatac agacgacctc
     7681 ttagatgaaa aactgaaaaa taacctcggc ttaaaatttg catttcgttc cactgacctt
     7741 aacgagatta aaaagacctt agcctttttt ggtgtagacc cagaggacga aaacaatcag
     7801 aagcgattgc gtgatttgga aaacgggcaa tgccttatca gtgatttata tggtcgtgtc
     7861 ggtgtgatac agttccaccc tgtatttgaa gaactgctcc atgcctttga taccagacca
     7921 cctgtgcgaa aagaggtgta aatgtgaaac catcaatagt aaacagaata aaatcaaact
     7981 ggacgctgaa acgtctaggt aaagtggcaa tgacagtggc tttcacactt gtgattgcca
     8041 tttttctttt agccatgctg ggaacggtgg ttcaagctgc gggcttggta gatgatacgg
     8101 tcaatgtggc aaatgaatac agccgatacc cacttgaaaa ctatcaactg gatttttatg
     8161 tggataatag ctggggctgg cttccgtgga actggtcgga cgggattgga aaacaggtca
     8221 tgtatggact atatgccatt accaatttta tttggacaat cagtttgtat gtttccaatg
     8281 cgacaggtta cttagtacag gaagcctatt ccttagactt catttccgct acagcagatt
     8341 ccattggtaa gaatatgcag accttagctg gtgtgagtgc aaacggattt tcaacagagg
     8401 gtttctatgt tggattcctc ttactcttga ttttggttct tggggtttat gttgcctata
     8461 cgggactgat aaagagagaa accacaaagg caattcatgc cattatgaat tttgtgctgg
     8521 tgtttatcct atcggcttcc tttattgcct acgctcccga ctacattaaa aaaatcaatg
     8581 acttttcatc agacatcagt aatgccagtt tatcacttgg cacgaagatt gtcatgcccc
     8641 attccgatag tcaaggcaag gacagcgtgg acttaatcag agatagcctg ttttccatac
     8701 aggttcagca accgtggcta ctgcttcaat acaacagttc agacattgaa agtatcggta
     8761 ttgaccgtgt ggaaagcctg ctctccacca gcccagattc caacaatggc gaagacagag
     8821 aaaaaattgt tgcggaagaa attgaagaca gaagcaatac caatctaacc attacaaaga
     8881 ccattaaccg tttaggtaca gtcttcttcc tatttgtctt caatattggg atttccatat
     8941 ttgtattcct attaacagga atcatgattt tctcgcaggt actttttatc atctatgcta
     9001 tgtttctgcc tgtgagcttt attttaagca tgattccatc atttgatggt atgtcaaaac
     9061 gagccataac aaagctcttt aataccattt tgacacgagc tggaatcaca ttgattatta
     9121 cgacagcatt tagtatttca accatgctct ataccttatc ggctggttat ccgttctttt
     9181 tgattgcttt tctacagatt gtgacctttg caggaatcta cttcaagctg ggcgatttaa
     9241 tgagtatgtt ttctctacag agtaacgatt ctcaaagtgt gggaagtcgt gtgatgagaa
     9301 aacctcgtat gcttatgcac gctcacatgc accgtctaca gcggaaactt ggacgttcca
     9361 tgactactct aggggctggg tctgccattg ttacaggtaa aaaaggacag tcgggttcgg
     9421 ggagttctgc aaggacacaa gcagatcact cccgaccaga cggaaaggaa aaatcaacac
     9481 ttggaaaacg tatcggtcaa accatcggta cagtagctga taccaaagac agaatggtag
     9541 acactgctag tggtttgaaa gaacaggtta aagatttgcc gaccaatgca agatatgcag
     9601 tatatcaagg aaaatccaaa gtaaaagaga atgtccgtga tttaaccagt agtatttctc
     9661 aaaccaaagc ggacagagcc agtggacgca aggaacagca ggaacaaagg cgaaaaacca
     9721 ttgcgaagcg tcgctctgaa atggaacagg tcaaacagaa aaaacagcct gcttcttctg
     9781 ttcatgaaag accgactaca agacaagaac aatatcatga tgaacagacc tcaaaacagt
     9841 ctaatattca gacttcatat aaggaatctc aacaagccaa acaagagcgt ccagcagtta
     9901 agtccgattt ttcaagtcca aaagtggaac gccaaggcaa taccgttcaa gaaaaaaccg
     9961 ttcaaaagcc agcaacttca accactacag cagatagaac ttcacaacgt ccaatcacaa
    10021 aagaacgtcc gtctactgtt caaagagtac cactacaaaa tacaagaagt agaccaccaa
    10081 tcaaaaccgc caccattaag aaagtcggta agaaaccatg aagttgaaaa ctttagtgat
    10141 tggtggttct ggattattct tgatggtctt ctcactgctt ctgtttgttg ccattttatt
    10201 ttcagatgaa caggacagcg gaatttccaa tattcattat ggaggtgtga atgtttccgc
    10261 agaagtgctg gctcataagc ctatggtaga aaaatatgcc aaagaatatg gcgttgaaga
    10321 atatgtcaac atacttcttg cgattataca ggtggaatcg ggcggtactg cggaagatgt
    10381 tatgcagtcc tcggaatccc tcggtcttcc acctaattca ttgagtacag aagaatccat
    10441 taagcaaggt gtgaagtatt tcagtgaatt attagccagt agcgaaaggc tcagtgtaga
    10501 tttagaatcg gttatccagt cctacaatta tggtggtggt ttcttagggt atgtggctaa
    10561 tcgtggaaat aaatatacct ttgaactggc tcaaagtttc tcaaaagagt attcaggtgg
    10621 cgaaaaagtg tcttacccca atcccatagc catacctatc aatgggggct ggcgatacaa
    10681 ctatggcaat atgttttatg tgcaactggt aacgcagtat cttgtcacaa cagagtttga
    10741 tgatgatacg gtacaagcca tcatggacga agcactgaaa tatgagggct ggcgatacgt
    10801 ttacggtgga gcttccccga ctacttcttt tgattgtagc ggactgacac aatggacgta
    10861 tggaaaagct ggaattaact taccacgaac cgcacaacag caatatgatg tgacccagca
    10921 tatcccacta tcggaagcac aagctggcga tttggttttc tttcattcta cctataacgc
    10981 tggctcttat attactcatg ttgggatata ccttggcaat aaccgtatgt ttcatgcagg
    11041 cgacccaatc ggttatgccg acttaacaag cccctactgg caacagcatt tagtgggagc
    11101 aggacgaatc aaacaatgag aaaggaagat ttaatgatga aatttagaaa aaatcagaat
    11161 aaagaaaaac agataccaaa ggaaaagaaa cctcgtgtct actataaggt caatcctcat
    11221 aaaaaggttg tgattgcctt gtgggtactt ttagggctta gtttcagctt tgcgatattc
    11281 aagcacttta cagctataga tactcatact attcacgaaa caactatcat agaaaaggaa
    11341 tacgttgata ctcatcatgt agaaaatttt gtagagaact ttgcgaaagt ctactattca
    11401 tgggagcaat ccgataagtc cattgataat cgaatggaaa gtctaaaagg ctatctgaca
    11461 gatgaacttc aagctctcaa tgttgataca gtacgcaaag atattcctgt atcgtcttct
    11521 gtaagaggat ttcagatatg gacggtagag ccaactggcg acaatgagtt taatgtaacc
    11581 tacagtgtag accagctcat tacagaggga gaaaatacaa agaccgtcca ctctgcttat
    11641 atagtgagtg tctatgtaga tggttctgga aatatggtac tggttaagaa tccgaccatt
    11701 accaacatac ctaagaaatc aagttataaa ccaaaagcca ttgaaagtga ggggacggtt
    11761 gattccatta caaccaatga aatcaatgag tttttaacga cgttcttcaa gctctatcct
    11821 acagcgacag ccagtgaact ttcctactat gtgaatgacg ggatattaaa accaatcgga
    11881 aaagagtaca tctttcaaga actggtaaat cctattcaca atcgtaagga taatcaagtc
    11941 acggtatcgc tgacagtgga gtatatcgac cagcagacca aagcaacgca ggtatctcaa
    12001 tttgatttgg tacttgaaaa gaacgggagt aattggaaga ttatagaata acaaatattg
    12061 gtacattatt acagctattt tgtaatcacg tactctcttt gataaaaaat tggagattcc
    12121 tttacaaata tgctcttatg tgctattatt taagtatcta tttaaaagga gttaataaat
    12181 atgcggcaag gtattcttaa ataaactgtc aatttgatag tggaaacaaa taattggatg
    12241 tcctttttta ggagggctta gttttttgta cccagtttaa gaataccttt atcatgtgat
    12301 tctaaagtat ccggagaata tctgtatgct ttgtatgcct atggttatgc ataaaaatcc
    12361 cagtgataag agtatttatc actgggattt ttatgccctt ttgggctttt gaatggagga
    12421 aaatcacatg aaaattatta atattggagt tttagctcat gttgatgcgg gaaaaactac
    12481 cttaacagaa agcttattat ataacagtgg agcgattaca gaattaggaa gcgtggacag
    12541 aggtacaacg aaaacggata atacgctttt agaacgtcag agaggaatta caattcagac
    12601 ggcgataacc tcttttcagt ggaaaaatac taagataaac atcatagaca cgccaggaca
    12661 tatggatttt ttagcagaag tatatcgttc attatcagta ttagatgggg caattctact
    12721 gatttctgca aaagatggcg tacaagcaca aactcgtata ttgtttcatg cacttaggaa
    12781 aataggtatt cccacaatct tttttatcaa taagattgac caaaatggaa ttgatttatc
    12841 aacggtttat caggatatta aagagaaact ttctgcggaa attgtaatca aacagaaggt
    12901 agaactgcat cctaatatgc gtgtaatgaa ctttaccgaa tctgaacaat gggatatggt
    12961 aatagaagga aatgattacc ttttggagaa atatacgtct gggaaattat tggaagcatt
    13021 agaactcgaa caagaggaaa gcataagatt tcataattgt tccctgttcc ctgtttatca
    13081 cggaagtgca aaaaacaata tagggattga taaccttata gaagtgatta cgaataaatt
    13141 ttattcatca acacatcgag gtcagtctga actttgcgga aaagttttca aaattgagta
    13201 ttcggaaaaa agacagcgtc ttgcatatat acgtctttat agtggcgtac tgcatttgcg
    13261 agattcggtt agaatatcgg aaaaggaaaa aataaaaatt acagaaatgt atacttcaat
    13321 aaatggtgaa ttatgtaaaa tcgataaggc ttattccggg gaaattgtta ttttgcagaa
    13381 tgagtttttg aagttaaata gtgttcttgg agatacaaag ctattgccac agagagagag
    13441 aattgaaaat cccctccctc tgctgcaaac gactgttgaa ccgagcaaac ctcaacaaag
    13501 ggaaatgtta cttgatgcac ttttagaaat ctccgacagt gacccgcttc tgcgatatta
    13561 tgtggattct gcgacacatg aaatcatact ttctttctta gggaaagtac aaatggaagt
    13621 gacttgtgct ctgctgcaag aaaagtatca tgtggagata gaaataaaag agcctacagt
    13681 catttatatg gaaagaccgt taaaaaaagc agagtatacc attcacatcg aagttccacc
    13741 gaatcctttc tgggcttcca ttggtctatc tgtagcaccg cttccattag ggagcggagt
    13801 acagtatgag agctcggttt ctcttggata cttaaatcaa tcgtttcaaa atgcagttat
    13861 ggaggggata cgctatggct gtgaacaagg attgtatggt tggaatgtga cggactgtaa
    13921 aatctgtttt aagtatggct tatactatag ccctgttagt accccagcag attttcggat
    13981 gcttgctcct attgtattgg aacaagtctt aaaaaaagct ggaacagaat tgttagagcc
    14041 atatcttagt tttaaaattt atgcgccaca ggaatatctt tcacgagcat acaacgatgc
    14101 tcctaaatat tgtgcgaaca tcgtagacac tcaattgaaa aataatgagg tcattcttag
    14161 tggagaaatc cctgctcggt gtattcaaga atatcgtagt gatttaactt cctttacaaa
    14221 tggacgtagt gtttgtttaa cagagttaaa agggtaccat gttactaccg gtgaacctgt
    14281 ttgccagccc cgtcgtccaa atagtcggat agataaagta cgatatatgt tcaataaaat
    14341 aacttagtgt attttatgtt gttatataaa tatggtttct tgttaaataa gatgaaatat
    14401 tttttaataa agatttgaat taaagtgtaa aggaggagat agttattata aactacaagt
    14461 ggatattgtg tcctgtatgt ggaaataaaa cacgattaaa gataagggaa gatactgaat
    14521 taaaaaaatt ccccctctat tgtccgaaat gcagacaaga aaatttaatt gaaataaagc
    14581 agttcaaagt aactgtgatt acagagccag acgcaaagac gcagagccga taaaatgaga
    14641 ttaatacaat ctcattttat cggctctttc cgttatgtat ggattctttt aattagtctt
    14701 cgatgtttct tgcttcgttg ataccgctgg ctaaagattc cattaaggat agttctttgt
    14761 ctgtaaagct atccatgtat ttctctatct gtaatcgtcg ggtgcttttt accaagttat
    14821 tagcaggtaa gaaaaattca tcaacggaaa catgaagtaa cgatacaagg tcataaagaa
    14881 cttgtatgct ggggtgttgc cctttatttt caatattagt taagtaccgt gggtcaattt
    14941 caatcaatgc tcccacttgt tcacgagtta aacctcgttt caatcgagct tctttaatgg
    15001 ctaaaccaaa ggctctaaaa tcatatttat cttctttttt acgcatagta gaccacctct
    15061 atacatttta ttgttcctac tgaattaaaa acaggtatag aaaaacgtgt tatatggttt
    15121 ataggtttat atttaataaa aagcactact aaacgccaat aaaaaaaacc gttatatggt
    15181 agtgctattt acgctgttaa aatattgtat attacttcca aatggcggtt tgttggaggt
    15241 caacgtcgcc atgaagtaca tcatatacaa taaatttcct tacattgggt tcttgtcaaa
    15301 aaaagtcgtc tatctgcaat agataagtac gtccaccaat gtggttttat aaatcatata
    15361 gatagaataa cagaagcatg taaacagaga aataaatctg tttatatgct tttttggcta
    15421 ttcagaactt ttttacaaag tttatttatc agtaatgcaa caaatccccc tttcacattg
    15481 ggactaagag tgaaaggaga taaacgagca aggctcactt cctttcctag acagaaaggg
    15541 ggtgagaaac atgaaaccat cttcttttca gaccacaata gaaaatcagt ttgactatat
    15601 ctgtaaacgt gctatggaag acgagcgaaa gaattatatg ctttatcttt caaggattgc
    15661 aaagcgtgag gtgtcctttt cggatgttgg cgattatctt gttagccagt ttgcgacaac
    15721 agataactat tcaactgact ttcagatttt tacactcaat gggttatcag taggcgttga
    15781 aaatgatttg ttgagtgaag cattacgtga gttgccagac aagaaacgtg aaattctact
    15841 gctgttttac tttatggaca tgagcgattc agaaattgca gacctgttga aattgaaccg
    15901 ttctactgtc tatcggcata gaaccagtgg actagcctta attaaaaagt ttatggagga
    15961 atttgaagaa tgaaaacaca atatcctatg attccctttc ctctcattgt aaaggcaaca
    16021 gatggcgata ccgaagcgat taaccagatt ctacatcatt acagagggta cataacgaag
    16081 cgttccctac gacttatgaa agatgaatat ggcaatcaaa gtatggtcgt tgatgaagtc
    16141 ttacgtggaa gaatggaaac cagactgatt acaaagattt tgtcatttga aattaagtaa
    16201 tatcctctct cctttcgtgg aagcgtgcta aaccattcca cgcttcccga acagggaggt
    16261 ttgttattcc accaaagcat attgagcttt caatgtgttt tgataggcta acgagccatt
    16321 gttctttgaa aactgaataa aagtaatcga atacgtttcg ataagaaaag agccaacgga
    16381 actaaccgcc atgacctatc ttataaagat agcgagcgat tcatgttagt gatccgagaa
    16441 gcaatcttta gcaggattgc ctgcaacgac attcttatcg tgataatgat actcccatac
    16501 agtcaatagt ccgagcgtga taaaaccgtc gcaggcaatg agtatggcta catgagaacc
    16561 atgcaggggt ggaactcccg tgagctttgc taaagctgtt cgattgctgg taaaacaact
    16621 tttatgaaat ccaaataagt gatttggaaa ggaggatttt atgaagcaga ctgacattcc
    16681 tatttgggaa cgttataccc taaccattga agaagcgtca aaatattttc gtattggcga
    16741 aaacaagcta cgacgcttgg cagaggaaaa taaaaatgca aattggctga ttatgaatgg
    16801 caatcgtatt cagattaaac gaaaacaatt tgaaaaaatt atagatacat tggacgcaat
    16861 ctagcgtcgc caaagggtct tgtatatgat aaaatagtat taagtcgtat caaggctctt
    16921 tccataaagg aaaggagcaa atgccatgtc agaaaaaaga cgtgacaata aaggtcgaat
    16981 cttaaagact ggagagagcc aacgaaaaga cggaagatac ttatacaaat atatagattc
    17041 atttggagaa ccgcaatttg tttactcgtg gaaacttgtg gctacagacc gagtaccagc
    17101 aggaaagcgt gattgtatct cacttagaga gaaaatcgca gagttacaga aagacattca
    17161 tgatggtatt gatgttgtag gaaagaaaat gacactctgc cagctttacg caaaacagaa
    17221 cgctcaaaga ccaaaggtta gaaaaaacac tgaaactgga cgcaaatatc ttatggatat
    17281 tttgaagaaa gacaagttag gtgtaagaag tattgacagt attaagccat cagacgctaa
    17341 agaatgggct attagaatga gtgaaaatgg ttatgcttat caaaccatca ataactacaa
    17401 acgttcttta aaggcttcat tctatattgc tatacaagat gattgtgttc ggaagaatcc
    17461 atttgacttt caactgaaag cagttcttga tgatgatact gtccctaaga ccgtactaac
    17521 agaagaacag gaagaaaaac tgttagcctt tgcaaaagct gataaaacct acagcaaaaa
    17581 ttatgatgaa attttgatac tcttaaaaac aggtcttcgt atttcagagt ttggtggttt
    17641 gacacttcca gatttagatt ttgagaatcg tcttgtcaat atagaccatc agctattgag
    17701 agatactgaa attgggtact acattgaaac accaaagacc aaaagtggcg aacgtcaagt
    17761 tcctatggtt gaagaagcct atcaagcatt taagcgagtg ttagcgaatc gaaagaatga
    17821 taagcgtgtt gagattgatg gatatagtga tttcctcttt cttaatagaa agaactatcc
    17881 aaaagtggca agtgattaca acggcatgat gaaaggtctt gttaagaaat acaataagta
    17941 taacgaggat aaattgccac acatcactcc acatagtttg cgacatacat tctgtaccaa
    18001 ctatgcaaat gcaggaatga atccaaaggc attacagtac attatgggac atgctaatat
    18061 agccatgacg ctgaactatt acgcacatgc aacattcgat tctgcaatgg cagaaatgaa
    18121 acgcttgaat aaagagaagc aacaggagcg tcttgttgct tagtagtaca aatgaattta
    18181 ctacttattt accacttctg acagctaaga catgaggaaa tatgcaaaga aacgtgaagt
    18241 atcttcctac agtaaaaata ctcgaaagca catagaataa ggctttacga gcatttaaga
    18301 aaatataaaa agataattag aaatttatac tttgttttta ttaaaaagca gcaaactata
    18361 aactagtagg ttccacacta aatgtagccc catactgccc cacaagtccg atttatagcg
    18421 taccatccct aaaaacattc ccaatgaaac atataaacac caagctagaa tggttcctgg
    18481 atgatgagct aaggcaaata aaacacttgt caaagcaact cgaatatcta attttctaac
    18541 caagttccat aaaatttctc tatacaaaaa ttcttcaacc atactcgcat tgattaagaa
    18601 caataaaaat gaaaaccaag gaacttgatg ttgaagccca attaagtttg cttgatttgt
    18661 gctttcttga gcatgaatca gactaaaata tagactgata atcagtaggc taacgaatcc
    18721 aataccaatc cactttatcc tagtttccat attgaccttg gccacttgtt ttcgttgacc
    18781 atacatccat aaaaaagaaa tgagcgacgc tccatagata atctgtagta tagttaactc
    18841 accgatacaa agaaatttca gtaagtataa ggataccaat aggacattta cttgttggaa
    18901 tatataaact ggaattattc ttttcatagt tacctccgaa ataaatcttc ataatctaaa
    18961 tctaatacct gcacaatcct ctctacccat ggactttgag gcattcgttg ttccatcttg
    19021 tagtgacgaa tcttttgata caaacgattc aattcacttg gatagtgaaa ctctcccgca
    19081 aacatttttc tggttaactc aatccagctg atatttcttt cagccaaaat aatggacaag
    19141 ttctcccaaa atcgttcagc catattgctt ctcctttagt tagataaata atgtgtttgt
    19201 gccatgtaaa tcaattgttt cgtatctctt ggtaataaag ccctagcttc ctccaaattt
    19261 agatttggat aaactcgctt atttgaaacc gcaagaggaa gtctgatggt tagttcagga
    19321 ttttttaata tcatttcaat gaaatccgtt agtcttaaat tgtcacggtt cttaaatcgt
    19381 aataaattag gagataaaaa ctcaaaacaa tctgaagaat agctcatcat ctcaattaat
    19441 ttatcccttg tcatttcaga aatcgaatga caggatacct caatgccata gttttggaag
    19501 aattctaaaa gaagttgatt tctatggtta tttttactta gatagagatc aatcatgtga
    19561 gacctcccaa agattcggtt ccatttgata ttctgagacg attaaggaat ctaataaatt
    19621 ggagaagtta attgatttct tgtcttcatc ataagctttt acagttactt gggttgtaag
    19681 tattccctct tttccctcgg ctcgatagcc ttgcccatat aaaacaaaaa caagattatg
    19741 attatcatct ataaaggcat cagctccgtt ctttatatcc tgactttcaa ggaattccat
    19801 aatgttttga agataggatt cgtaaaatag ggggtaattg tgttttttat ggtaataatc
    19861 taaaaatgtc acctcaaact cacatggata attgggcatc aaaaatattt gttcatccaa
    19921 ctgcatcatt tctgcatcat gtaattctgt ttctaattca tcacaatata gtattgactc
    19981 tttatttagc gctttcatct ttttcctcta tttcttttaa tttttttgcg attgcggcaa
    20041 tcacaggaac agttacacta ttaccagctt gtttatagag ctgactatta ctagagactt
    20101 ttctagc
//
LOCUS       DAVBOG010000039        18492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.039, whole genome shotgun sequence.
ACCESSION   DAVBOG010000039 DAVBOG010000000
VERSION     DAVBOG010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.039"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..347)
                     /locus_tag="VQ865_001551"
                     /pseudo
     CDS             complement(1..347)
                     /locus_tag="VQ865_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(423..857)
                     /locus_tag="VQ865_001552"
     CDS             complement(423..857)
                     /locus_tag="VQ865_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3135875.1"
                     /translation="MLLVLVSLVHSFGSVSIIAHTIHQKFNLKVPNYRQEEDWARMGL
                     PITRKEISNWHIKASQYYLESLYNLLREKLLEQPLLHADETSYRVLESDSHLTYYWTF
                     LSGKAENQAITLYHHDQRRSGLVVQEFLGDYSGYVHCDMLRQ"
     gene            complement(933..1783)
                     /gene="rfbD"
                     /locus_tag="VQ865_001553"
                     /pseudo
     CDS             complement(933..1783)
                     /gene="rfbD"
                     /locus_tag="VQ865_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647909.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
     gene            complement(1849..2898)
                     /gene="rfbB"
                     /locus_tag="VQ865_001554"
     CDS             complement(1849..2898)
                     /gene="rfbB"
                     /locus_tag="VQ865_001554"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000141505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HET3135876.1"
                     /translation="MTEYKNIIVTGGAGFIGSNFVHYVYENFPDVHVTVLDKLTYAGN
                     RANIEEILGNRVELVVGDIADAELVDKLVAQADAIVHYAAESHNDNSLNDPSPFIHTN
                     FIGIYTLLEAARKYDIRFHHVSTDEVYGDLPLREDLPGHGEGPGEKFTAETKYNPSSP
                     YSSTKAASDLIVKAWVRSFGVKATISNCSNNYGPYQHIEKFIPRQITNILSGIKPKLY
                     GEGKNVRDWIHTNDHSSGVWTILTKGQIGETYLIGADGEKNNKEVLELILKEMGQATD
                     AYDHVTDRAGHDLRYAIDASKLRDELGWKPEFTNFEAGLKATIKWYTDNQEWWKAEKE
                     AVEANYAKTQEIITV"
     gene            complement(2908..3504)
                     /locus_tag="VQ865_001555"
     CDS             complement(2908..3504)
                     /locus_tag="VQ865_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase family
                     protein"
                     /protein_id="HET3135877.1"
                     /translation="MTDNFFGKTLAARKVEAIPGMLEFDIPVHGDNRGWFKENFQKEK
                     VLPLGFPESFFAEGKLQNNVSFSRKNVLRGLHAEPWDKYISVADGGKVLGSWVDLREG
                     ETFGNTYQTVIDASKGIFVPRGVANGFQVLSDTVSYSYLVNDYWALELKPKYAFVNYA
                     DPSLGIEWENLEEADVSEADKHHPLLKDVKPLKKEDLE"
     gene            complement(3505..4362)
                     /gene="rfbA"
                     /locus_tag="VQ865_001556"
     CDS             complement(3505..4362)
                     /gene="rfbA"
                     /locus_tag="VQ865_001556"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000676139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HET3135878.1"
                     /translation="MKGIILAGGSGTRLYPLTRAASKQLMPVYDKPMIYYPLSTLMLA
                     GIRDILIISTPQDLHRFQELLQDGSEFGIKLSYAEQPSTDGLAIGEEFISDDSVALIL
                     GDNIYHGPGLSTMLQKAAKKEKGATVFGYQVKDPERFGVVEFDTDMNAISIEEKPEYP
                     RSNYAVTGLYFYDNDVVEIAKSIKPSPRGELEITDVNKVYLDRGDLSVELMGRGFAWL
                     NTGTHESLLEASQYIETVQRMQNVQVANLEEIAYRMGYISREDVLALAQPLKKNEYGQ
                     YLLRLIGEA"
     gene            4576..5882
                     /locus_tag="VQ865_001557"
                     /pseudo
     CDS             4576..5882
                     /locus_tag="VQ865_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(6170..6352)
                     /locus_tag="VQ865_001558"
     CDS             complement(6170..6352)
                     /locus_tag="VQ865_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135879.1"
                     /translation="MAVIFKNVLIEEKTEEEKQHILSILNGEYDLSDDVSCRLRRLNE
                     ESKRLEVFVKETNSLV"
     gene            complement(6568..7800)
                     /locus_tag="VQ865_001559"
     CDS             complement(6568..7800)
                     /locus_tag="VQ865_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002992300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide sugar dehydrogenase"
                     /protein_id="HET3135880.1"
                     /translation="MKIAVAGTGYVGLSIAILLAQHHQVVAVDIIPEKVELINKKKSP
                     IQDDYIEKYLAEKELNLVATLNAEEAYENADFIVIAAPTNYDPKKNFFDTSSVEAVIE
                     AVMKYNPDAIIIIKSTVPVGYTKSVRRKFLTDNIMFSPEFLRESKALYDNLYPSRIII
                     GTDKDDKDLVKSAEIFVKMLQEGAVKENIETLYMDFTEAEAVKLFANTYLALRVSYFN
                     ELDTYSEMKGLDTQAIIDGVCLDPRIGSHYNNPSFGYGGYCLPKDTKQLLANYSDVPQ
                     EMITAIVQSNRTRKDYIADRILDLAGSYVGNDFYKPDKEKEIVVGIYRLTMKSNSDNF
                     RQSSIQGIMKRLKAKGVTIIIYEPTLESGTTFYGSQVVNDFEIFKKSSQVIVANRFDE
                     TLEDVRGKVYTRDIFKRD"
     gene            complement(7829..8899)
                     /gene="gla"
                     /locus_tag="VQ865_001560"
     CDS             complement(7829..8899)
                     /gene="gla"
                     /locus_tag="VQ865_001560"
                     /EC_number="5.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001214397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate 4-epimerase Gla"
                     /protein_id="HET3135881.1"
                     /translation="MRGKTILITGVAGFIGSNLVRKLLELEGTMTIIGLDNLNDYYDI
                     ALKDYRLLQLNKLIQDYPEKNWIFIKGDIADKMLINKIFKSYHPQIVVNLAAQAGVRY
                     SITNPDVYIESNIVGFHNVLEACRHSYEIYDGGVEHLVYASSSSVYGGNKKIPFATED
                     KVDNPISLYAATKKTNELQAYAYSKIYNIPSTGLRFFTVYGPAGRPDMAYFGFTDKLR
                     SGSDIEIYNHGNCKRDFTYIDDIVEGIVRVMQSAPKKLVGSDNLPLAPYKVYNIGNSK
                     PENLLDFVDVLQQELIKAGVLPENYDFDSHKKLVPMQPGDVPVTYADTSDLERDFGFK
                     PKTSLREGLRKFAEWYKDYYNV"
     gene            complement(8967..10136)
                     /locus_tag="VQ865_001561"
     CDS             complement(8967..10136)
                     /locus_tag="VQ865_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HET3135882.1"
                     /translation="MRLSKKYWFALTSKFLLILLTLLSSIIINRGLGVEKKGDYAYVM
                     NLVEIFYILGGVGLGQAYSTFKRNHSNEYQNKFVFLTFIQGLLFGIIGLIIVLADVPI
                     DYGGVIIVLSSLSIMRTNLTMIAVIENSIKRNKIVLGVSVVYSVMLVLLLLFHLVSIE
                     MVFLVYAINEFLRIILFLYYYNMFPVFEHISIKEFFTIYKFGFLSMILTLLITFNYSI
                     DIIMLKQMSSSYNVGIYSVAVTFSNMFLMVPDSFKEILFGDSAKRTFEKNKAINAIKV
                     SFLFMILLIIGFLSFGEFAITLLYGSSYIKAFPITLVIFLGSLSMIFFKILQPIYISQ
                     GKQSVAIKILSVSALINISLNWYLIPNYQITGAAIASAISYTVCGLFFIIDYLRN"
     gene            complement(10322..11626)
                     /locus_tag="VQ865_001562"
     CDS             complement(10322..11626)
                     /locus_tag="VQ865_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000672721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide repeat unit polymerase"
                     /protein_id="HET3135883.1"
                     /translation="MKFSLQSNDIKNKIILLVGVVFSGTLILCSENNDVTIPLFSMIF
                     LSFMAMIIVKFNIFHPYVWYSSFFTIYSISYPLLYRMEYINYGYTKDLIFMQWLALAT
                     LLLTLPSKAIVLSERKINLNNNNYLLFLNNMNTFITTVAIIYLLGSGFRNKGEIYSGA
                     NIVIMLVFSLVYFMILIHTYQLFIQLSTKKWRLLNCNTNTAIVICLFSIVTGERDYMF
                     TLFILDVIILFYFHKIKRFYLVMLVPLAALLIPLSAVFKYTLLSGQVSSINTNNIWFD
                     LLDGEFVSASRNLQILILHNMGNYFEGRSFFNDIVRIFYNTGYSNQTWFMDTFFPNVH
                     STKYGFTLVGEGYVNGGYFGIVMIFMLTGFLMRFLYINAQRNIYGMLIYLYMIPIFIY
                     STRADFANILSPLLKYAILGTLVIVFINRMVLISPLDEMGGE"
     gene            complement(11743..12897)
                     /locus_tag="VQ865_001563"
     CDS             complement(11743..12897)
                     /locus_tag="VQ865_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000862350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3135884.1"
                     /translation="MKVFIATEFRCTIYKNEIYLKPKAYFIYERYAKAFGEIVLCSRY
                     EKVESYPEGYHKANFINKFIPIEGLHQVLFGQNKNKIIEGMIDSDLIVVRIPSIIGSK
                     TADYALKIGKPYLTEIMGDAWDSYWYHSLKGKLLAPYIYAKTKSIVKNANYCIYVTEK
                     YLQDRYPNIKSNIVASNVNITSVENRSLKSRLYKLKKFNPQKISIMTTASVNVRAKGH
                     RFVLEAMKRLEIQGILLDYYLAGDGDQSFLKKKAEELGVANRIHFLGELTTSQIYEYL
                     DKVDLYIQPSLQEGLPRAVIEAMSRACPCIGSNKAGIPELLGPHCLFTPSSSQAIAGS
                     IIDFISMDKEKMVIKQFEFSKKFLSSVLNKRRSDYFAQIRRELNNSDGLD"
     gene            complement(12894..13445)
                     /locus_tag="VQ865_001564"
     CDS             complement(12894..13445)
                     /locus_tag="VQ865_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HET3135885.1"
                     /translation="MNRIIKNIVGLLRANICLILLKVCRNKDLTFHYFLKFGKNVTVE
                     QESNAKLILGKKIRVNAGGVLKVRKGAKLKISDDVFLSNNCMIACRKYIDIKSGVKCG
                     PGVLIYDHDYDVSVPGGLKAKKFKTAPVMIGENVWIGANSIVLKGVSIGENSVVAAGS
                     VVTKDIPADTIFIQKRLSREMKL"
     gene            complement(13438..14574)
                     /locus_tag="VQ865_001565"
     CDS             complement(13438..14574)
                     /locus_tag="VQ865_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001053205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HET3135886.1"
                     /translation="MNLQKKKIMLITNHDDDIYCFRKEVIESLVEYGYEVLVSCPYGD
                     KIELMKSIQFEYEDITIDRRGINPLKDIRLFLSYIRLLRKYRPDVVLTYTVKPNVYAS
                     LAATILGIKYINNVTGLGSVLTMGSCVRSLVLLLFRISFRKSNCVFFQNEYNMKMLKT
                     LGLILGDSKLIPGSGVNIEKYPVQQYPNGGNGIQGETIVFNFIGRILKEKGIDTYLAA
                     AQIIKSRYPKTEFNIIGFIEPTESNYELKICDLEKKGIVYYLGQQKDVIPHITRSHAI
                     IHPSVYGEGMSNVLLENASSGRVLITTDNPGCKEIVKDRETGYIFQGGNVEELVSILE
                     VFLGLENEKRKEMGLQGRMYIEQYFSRQIIIDAYLDKIKGALDE"
     gene            complement(14715..15380)
                     /gene="cpsD"
                     /locus_tag="VQ865_001566"
     CDS             complement(14715..15380)
                     /gene="cpsD"
                     /locus_tag="VQ865_001566"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase
                     CpsD"
                     /protein_id="HET3135887.1"
                     /translation="MPTLEIAQKKLEFIKKAEEYYNTLCTNIQLSGDKLKVISVTSVN
                     PGEGKTTTSVNIAMSFARAGYKTLLFDGDIRNSVMSGFFKSREKITGLTEFLSGTADL
                     SHGLCDTNIENLFVVQSGSVSPNPTALLQSKNFNDMIETLRKYFDYIIVDTPPIGIVI
                     DAAIITQKCDASILITATGEANKRDVQKAKQQLEQTGKLFLGVVLNKLDISVDKYGVY
                     GRK"
     gene            complement(15390..16082)
                     /gene="cpsC"
                     /locus_tag="VQ865_001567"
     CDS             complement(15390..16082)
                     /gene="cpsC"
                     /locus_tag="VQ865_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000664160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular polysaccharide biosynthesis protein
                     CpsC"
                     /protein_id="HET3135888.1"
                     /translation="MKEQNTLEIDVLQLFRALWKRKLVILLVAIITSSVAFAYSTFVI
                     KPEFTSTTRIYVVNRNQGEKPGLTNQDLQAGAYLVKDYREIVLSQDVLEEVISDLKLD
                     LMPKGLANKIKVTVPVDTRIVSVSVSDRVPEEASRIANSLREVAAQKIISITRVSDVT
                     TLEEARPAISPSSPNIKRNTLIGFLAGVIGTSVIVLLLELLDTRVKRPEDIENALQMT
                     LLGVVPNLGKLK"
     gene            complement(16091..16822)
                     /locus_tag="VQ865_001568"
     CDS             complement(16091..16822)
                     /locus_tag="VQ865_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-protein phosphatase CpsB"
                     /protein_id="HET3135889.1"
                     /translation="MIDIHSHIVFDVDDGPKSREESKALLAESYRQGVRTIVSTSHRR
                     KGMFETPEEKIAENFLQVREIAKEVADDLVIAYGAEIYYTLDALEKLEKKEIPTLNDS
                     RYALIEFSMHTSYRQIHTGLSNILMLGITPVIAHIERYDALENNEKRVRELIDMGCYT
                     QINSYHVSKPKFFGEKYKFMKKRARYFLERDLVHVVASDMHNLDSRPPYMQQAYDIIA
                     KKYGAKKAKELFVDNPRKIIMDQLI"
     gene            complement(16824..18269)
                     /locus_tag="VQ865_001569"
     CDS             complement(16824..18269)
                     /locus_tag="VQ865_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HET3135890.1"
                     /translation="MSRRFKKSRSQKVKRSVNIVLLTIYLLLICFLLFLIFKYNILAF
                     RYLNLVVTALVLLVALVGLLLIIYKKAEKFTIFLLLFSILVSSVSLFAVQQFVGLTNR
                     LNATSNYSEYSISVAVLADSKIENVTQLTSVTAPTGTDNENIQKLLADIKSSQNTDLT
                     VNQSSSYLAAYKSLIAGETKAIVLNSVFENIIESEYPDYASKIKKIYTKGFTKKVEAP
                     KTSKNQSFNIYVSGIDTYGPISSVSRSDVNILMTVNRDTKKILLTTTPRDAYVPIADS
                     GNNQKDKLTHAGIYGVDSSIHTLENLYGVDINYYVRLNFTSFLKMIDLLGGVDVHNDQ
                     EFSALHGKFHFPVGNVHLDSEQALGFVRERYSLTDGDRDRGRNQQKVIVAIIQKLTST
                     EVLKNYSSILQGLQDSLQTNIPIETMIDLVNTQLESGGNYKVNSQDLKGTGRMDLPSY
                     AMPDSNLYVMEIDDSSLTVVKAAIQDVMEGR"
BASE COUNT         5957 a         3777 c         2701 g         6057 t
ORIGIN      
        1 ttcaaaatag tcttaaaggt ttcttcatac ttgaggctgt attcaattgc ccttcctagt
       61 tttgaacctg ctaaaactga ctgacgccgg caccaagcaa agaagtcttc cattaggggc
      121 tggagatgtt cttgacgttt ctgtagtcgt tcatcagctg gcaaagcctc ccagtctctt
      181 tccaaggaaa ataactgatc acaataagct aaacctttag ctcctaagga tgatttatcc
      241 gtttgcttgg ggggcgcttc aaaaaacttc cttctcacat gtgcccaaca tccaacaagt
      301 tcagcttctt ccagttgacg ataagcttct agcggttcgc agtttaccaa gcttagcgtc
      361 gccttgctcc taaaccttgg actgctatcg cataggcaga actagaggac taaagtccta
      421 agttactgcc gcaacatatc acaatgcaca tagccagaat aatctcctag gaattcttgt
      481 actactaaac cactccgacg ctgatcatgg tggtacagcg tgattgcttg attctcagct
      541 ttcccagaca aaaaagtcca atagtaggtc agatggctat cactctctag aacccgataa
      601 gaggtttcat ccgcatgaag aagaggttgt tctaacaact tttctcgtaa aaggttataa
      661 agggactcta aatagtattg acttgccttg atatgccaat tagagatttc cttacgtgtg
      721 attggtaaac ccatcctagc ccaatcttct tcttggcgat aattgggtac cttcagatta
      781 aacttctgat ggatggtgtg agcgataata gaaactgagc caaagctatg caccaaagag
      841 accagcacca acaacaagat aattgtacat cttaagctcc tttggagttc attatctgcc
      901 tcttttatta gactagaaaa tcattctact acttatctca cttcttgttt gtaaaattct
      961 tgcaatgcat cttgccaagt tggaataaca aatccagtag ctttggcttt ggccaggctc
     1021 atcgttgagt ttagcggacg ttgagctttg gctggaaatt gactggatct actggcttga
     1081 cttcgacatc tgtatctttc aaaatttcaa ctgcaaaatc ataccatgtt gtgtcttctg
     1141 tcgcatcatt tgacaaatga taataaccaa attccttacg attttcagct aggtagatca
     1201 tgaattcagc caaggtacga gtccaagtcg gacgaccgta ctggtcattt acaactgtta
     1261 aagtcttatg agttttcgca agattttgca tggtaaaaac gaagtttttg ccataatttc
     1321 caaataccca ggcagtacgg ataatataga aattagacac atgcttctca actaactctt
     1381 cccccatacg cttagtgcgt ccatattctg tctgtggatc tggtcggtca tcaacttccc
     1441 actcttgtcc aactggtttc ttaccgtcaa agacctagtc cgtagaaata taaactagag
     1501 ttgcaccatg cttttcagat gcttttgcga cattttttgt ccccatcaca ttgatggcga
     1561 agtccaactc ttttccttca tcctctgctg catcaacagc ggtgtaggct gcacaatggt
     1621 agactaaagt cggtttcacc tcttcaaaaa ctttctcaac catttcttca ttggtaatgt
     1681 ccatctcagc cacatctact gccacgtatt cttcattacg ttcatccaat aaatagcgaa
     1741 gttccgttcc taattggcca tttgcccctg taattaaaat catctctaga cctttctaat
     1801 atgtaactct tcccaatata gcaataaaaa gcagcgattt cctgcttttt atactgtaat
     1861 aatctcctga gtcttagcat aattggcttc aacagcttct ttttctgctt tccaccattc
     1921 ttggttatct gtataccact tgattgttgc cttgagccca gcttcaaagt tggtaaattc
     1981 aggtttccac cccaactcat cacggagctt gctggcatca atcgcatagc gaaggtcatg
     2041 tcctgcacgg tcagtcacat gatcataggc atccgtagct tgtcccattt ccttaaggat
     2101 aagttccaaa acttccttat tgttcttctc accatcagcc ccaatcaagt aggtttcacc
     2161 gatttgccct tttgtcaaga ttgtccaaac tcctgaagaa tggtcattgg tatgaatcca
     2221 gtcacgaacg ttcttacctt caccgtaaag ttttggctta attccactta ggatgttagt
     2281 aatctgacgt gggatgaatt tttcgatatg ttgataagga ccgtagttat ttgaacagtt
     2341 ggaaatcgtt gccttgactc caaaagaacg cacccaggct ttgacaatca agtctgatgc
     2401 ggccttggtt gatgagtacg gagagcttgg gttgtatttt gtttcagcag taaatttctc
     2461 acctggtcct tcaccatgac ctggcaaatc ttctcgtaaa gggagatccc cataaacttc
     2521 atctgtcgat acatggtgga agcgaatatc atacttacga gcagcttcta aaagagtata
     2581 gattccaatg aagttagtat gaataaatgg cgatggatca ttgagcgaat tatcattgtg
     2641 gctttccgct gcataatgaa cgatagcatc tgcttgagca accaacttgt ctaccaactc
     2701 cgcatcagca atgtcaccaa caactaactc aacacgattg cctaaaattt cctcaatatt
     2761 cgcgcggttt ccagcataag tcaacttatc taggactgtc acgtgaacat ctggaaagtt
     2821 ctcgtaaaca taatggacaa agttagaacc gataaagcca gctccacctg tcacgataat
     2881 atttttgtat tcagtcatat tctttcctta ttccaaatct tcttttttca aaggcttcac
     2941 gtccttaagt aggggatgat gtttgtctgc ttcagatacg tctgcttctt ccagattttc
     3001 ccattcaata ccaaggcttg gatcagcgta gttcacaaag gcatacttgg gtttgagttc
     3061 aagagcccag taatcattga ccagatagct atatgacact gtatctgata aaacttggaa
     3121 gccattagct acgcctcgag gaacaaagat tcccttgctt gcatcaatta ctgtctgata
     3181 ggtattccca aaggtttcac cctcgcgtag atcaacccaa gaacccagaa ctttccctcc
     3241 atctgctaca gagatgtact tatcccaagg ctctgcgtgg aggcctcgaa ggacattttt
     3301 acgtgagaag gatacattgt tttgcaattt tccttctgca aagaaagact ctggaaatcc
     3361 aagtggaagc actttttcct tttggaaatt ttctttaaac cagccacgat tatctccatg
     3421 aacggggata tcaaactcca acatgcctgg aatagcttca accttgcgtg ccgcaagcgt
     3481 cttaccgaaa aaattatctg tcatctatgc ttctccaatc aaacggagca gatactgtcc
     3541 gtattcattt ttcttaagtg gttgggctaa ggccaataca tcttctcgac tgatatagcc
     3601 catacggtaa gcaatttctt ctaagtttgc tacctgaaca ttttgcatcc gttgcactgt
     3661 ttcgatgtac tgtgaagcct ctagtaaact ttcatgagtt ccagtattca gccaagcaaa
     3721 gccacgtccc ataagctcaa cagacaaatc accacgatct aggtaaacct tgtttacatc
     3781 tgtaatttcc agttcaccac gagggcttgg tttaatactc ttggcaattt cgacaacatc
     3841 gttatcatag aaatacagtc ctgtcactgc atagttggag cgaggatact ccggtttttc
     3901 ttctatggaa atagcattca tgtctgtatc aaactcaacc acaccaaaac gctctggatc
     3961 cttcacttgg tagccaaaaa cagtcgcacc tttctctttc ttggctgctt tttgaagcat
     4021 tgtgctcaga ccaggaccat ggtagatatt gtcgcctaaa atcaaggcaa cgctatcgtc
     4081 agaaataaac tcttccccaa ttgccaaacc atctgtactt ggttgctctg cataagaaag
     4141 tttgatccca aactcagatc cgtcttgaag aagctcttga aatcgatgta aatcctgtgg
     4201 agtggaaata atcaaaatat ccctaatccc agccaacatc aatgttgaaa gtgggtagta
     4261 aatcatcggt ttatcataaa ccggcataag ttgttttgac gcagcgcgag tcaaaggata
     4321 taaacgtgtc cccgaaccac ctgctagaat aatacctttc atagtagggt acctttcttt
     4381 gttattttag agtcaattac tattaattgt gtactgctct aaaaagaaaa caatcatccc
     4441 atgttttata tggctctata atatttgtag tgggtaaatc ccttatagat attatggagc
     4501 ctattttgtt gtagaaaaaa agtcccatat gacctataat gaaaagcgac caaacaactc
     4561 attagaaaga ttcatatgga acaattacat tttatcacaa aactgctcga tattaaagac
     4621 ccaaacatca agattctaga tatcatcaat atggataccc acaaagaaat tatcgctaag
     4681 ctggattatg aggctccatc ttgccctgat tgtggaagtc taatgaagaa atatgacttt
     4741 caaaaaccgt ctaagatccc ttatcttgaa acgactggta tgcctactag aattctcctt
     4801 agaaagcgtc gattcaagtg ctatcactgt tcaaaaatga tggtcgctga aacttctatc
     4861 gtcaagaaga atcaccaaat ccctcgtatc atcaaccaaa agattgctca aaagttaatt
     4921 gaaaagattt ctatgactga tattgcccat cagctttcca tctcaacttc aactgttatt
     4981 cgtaagctca atgattttca ctttaaacat gatttttctt gtcttcctga gattatgtct
     5041 tgggatgagt atgcttttac aaagggaaag atgagcttca ttgcgcaaga ttttaacaat
     5101 ctcaatatca tcactgttct tgagggtaga acacaagcta tcattcgaaa tcactttctt
     5161 cgctacgata gagttgtccg atgtcgcgtc aaaatcatta ctatggatat gtttagccct
     5221 tactatgact tggctaaaca gtttcgcttt caaatttcta ggctcaggct gaaacagtct
     5281 cccagactgt ttcactcccg aatgctaaaa tcgtgttgga tcgctttcac attgtacaac
     5341 atcttagccg tgctatgagt cgtgtgcgtg ttcaaatcat aaatcagttt catcgaaaat
     5401 cccatgaata caaggctatc aagcgctact ggaaactcat tcaataggat agtcgtaaac
     5461 tgagtgataa acatttttat cgtcctactt ttcgtatgca ttgaaccaat aaagagattt
     5521 taaacaagct tttgagttat tcggaagact tgaaacacca ctatcaactc tatcagctct
     5581 tgctttttca tttccagaat aaggaaccag agaaattttt cggacttatt gaggacaatc
     5641 ttaagcaggt tcatcctatt tttcagaccg tctttaaaac cttcctcaaa gataaagaaa
     5701 agattgtcaa cgcccttcaa ctacactatt ctaacgccaa actggaagcg accaataatc
     5761 tcatcaaact tatcaagcgc aatgcctttg gttttcgaaa ctttgaaaac ttcaaaaaac
     5821 ggattttcat cgctctgaac atcaaaaaag aaaggacgaa atttgtcctt tctcgagctt
     5881 agctgacttc aacccactac agttgacaaa gagcctaaaa attcacttac ttcatattac
     5941 atttagcatg aaatgaaata agcgaattct actttgtttg catacaatta aaaatcaatt
     6001 cctaaggatg ttttaaataa ctgtgtaaaa ggcataattt caccatttct tagtttttca
     6061 atgctaaatt acatagtaac tggagagcta ttagaaatct ctaacttcct catagttaaa
     6121 aaatgacaat gagatactta ttgatttcaa ttcattaaca gaatacgaac tagacaagtg
     6181 agttcgtctc cttaacaaac acttccaagc gtttactttc ctcattcagt cgtcgtaatc
     6241 tacaacttac atcatcagat aagtcatact caccatttag aatagataga atatgttgtt
     6301 tttcttcttc agtcttctct tcaataagca catttttaaa aattactgcc attatcagca
     6361 cctcacttcg aaggaatata tgcaactata tcctattaag tcaatctcta ctgacaaaag
     6421 aagtatattt acttcactaa gtgcgagcga gaatatagaa atatctttat tgttttagat
     6481 gagttgtcgc tatcctccag ctagttttta actattctat cattcaaatg atatagatta
     6541 ttagggacta gaaatataca aattgattta atctctctta aaaatatccc tagtataaac
     6601 tttacccctc acatcttcta aagtctcatc aaaacgattt gcaacaatca cttgactaga
     6661 tttcttaaat atttcaaaat cattaactac ttgactacca tagaaagtag taccactttc
     6721 aagagttggt tcgtaaataa taatagtaac accttttgct ttcaaacgct tcataatacc
     6781 ttgaatagaa gattgtctaa aattatctga attacttttc attgttaaac gataaattcc
     6841 tacaacaatc tctttttctt tatctggttt atagaaatca ttgcctacat aagatccagc
     6901 aagatctaaa atacgatctg caatataatc ttttcttgtc cgattacttt gtactatagc
     6961 tgttatcatt tcttgtggaa cgtcagaata atttgcaaga agttgcttgg tatctttagg
     7021 aagacagtaa cccccataac caaaagaagg attattgtag tgagaaccta ttctcggatc
     7081 taaacaaact ccatcaataa tcgcttgagt atctagtcct ttcatctcag aataagtatc
     7141 taactcgtta aaataggaaa cccggagggc aagataggta ttagcaaaaa gttttactgc
     7201 ttcagcttct gtaaaatcca tatacaatgt ttcaatattt tctttcactg caccttcctg
     7261 aagcattttt acaaaaattt cagcagactt taccaaatct ttatcatctt tatctgtacc
     7321 tataataatt cgactcggat ataggttatc atataacgct tttgactccc gtaaaaactc
     7381 aggactaaac ataatattgt ctgtaagaaa tttcctccgt actgactttg tatatccaac
     7441 aggaacagta cttttaatta ttataattgc atcaggatta tatttcataa ctgcttcaat
     7501 gacagcctcg actgaagatg tatcgaaaaa attttttttc ggatcataat tagttggagc
     7561 cgcaataact ataaaatccg cattctcata tgcttcctct gcattcaatg tagctacgag
     7621 attcaattct ttttccgcga gatatttttc tatataatcg tcttggatag gggacttctt
     7681 tttattgatt aactcaactt tctcaggaat gatatctacg gcaacaactt gatgatgttg
     7741 agccagtaag attgcaatag ataatccaac atatcctgta cctgctactg ctattttcat
     7801 aattttttcc tttctcaaaa cactctcgtt atacattata gtagtcttta taccactctg
     7861 caaactttct caaaccttct cgtaaagaag tttttggttt aaaaccaaaa tctctctcta
     7921 aatcacttgt atctgcataa gtaacaggaa catcgcctgg ttgcatagga actaattttt
     7981 tatgactatc aaaatcataa ttttccggca aaactcctgc cttgattagc tcctgttgaa
     8041 gaacatccac aaaatctaac aaattttcgg gtttactatt cccaatattg tacactttat
     8101 atggggctaa cggtaaatta tcagatccca ctagtttctt cggagctgat tgcatgaccc
     8161 ttactatccc ctcaacgata tcatctatat aagtaaaatc tcgtttacaa ttaccatgat
     8221 tataaatctc aatatcggaa ccacttcgca atttatctgt aaatccaaaa taggccatat
     8281 ctgggcgccc agcaggacca taaactgtaa aaaagcgtaa gcctgtcgaa ggaatattgt
     8341 aaatctttga ataagcatac gcttgaagtt catttgtttt tttagtcgca gcatatagtg
     8401 aaataggatt gtctacctta tcttctgttg caaacgggat ttttttattt ccaccatata
     8461 ccgatgagga cgatgcataa actaagtgtt ccacaccacc atcatatatc tcatacgaat
     8521 gacgacaagc ttccaacaca ttatgaaagc caacgatatt actttctata tatacatctg
     8581 gatttgtaat ggagtagcgt actcctgcct gggcagctag attaacaaca atctgaggat
     8641 gataactctt aaaaatctta ttaataagca ttttatctgc aatatcaccc ttgataaata
     8701 tccagttttt ttctggataa tcctgaatta gcttattaag ttgaagcaat cgataatctt
     8761 taagtgcaat atcatagtaa tcattcaaat tgtccaaacc aatgattgtc atcgttcctt
     8821 ctaattccaa taatttccta accagatttg atccaataaa accagctact cctgtaatta
     8881 gaattgtttt tcctctcata tcataatacc tcttgttatt tttatatttt catccactaa
     8941 tacacattct ttaacaacta ttataatcaa tttctaagat aatctataat aaaaaacaaa
     9001 ccacatacag tataagagat tgctgatgct atcgcagctc ctgtaatttg gtagttagga
     9061 attaagtacc agtttaaact tatatttatc aaagccgaca cagataaaat ttttatagct
     9121 acactctgtt taccctgaga tatataaatt ggttgtaaaa ttttaaagaa aatcatcgat
     9181 aagcttccta aaaaaatgac taatgttata ggaaatgcct ttatataact ggaaccataa
     9241 aggagcgtaa tcgcaaattc tccaaaagaa agaaatccaa taattaataa aatcataaat
     9301 agaaatgata cttttattgc atttattgct ttatttttct caaaagttct tttagccgaa
     9361 tcaccaaata aaatctcttt aaatgagtct ggaaccatca aaaacatatt agaaaacgta
     9421 actgcgacac tgtatatacc tacattataa ctactagaca tttgcttcaa cattatgata
     9481 tcaatactat aattaaatgt aattaataga gtaagaatca tagaaagaaa tccaaactta
     9541 tatatagtga aaaattcttt aatactaata tgttcaaaaa ctgggaacat attgtaatag
     9601 tataaaaata aaatgatacg taaaaattca ttaatagcat ataccaaaaa taccatctct
     9661 atagaaacta aatgaaatag taacaacaat actagcataa cggaatatac tacgcttact
     9721 cctaatacaa tcttattcct ctttatacta ttttctatta ctgcaatcat agtaagattt
     9781 gttctcataa tagatagact ggacaaaact attattaccc caccataatc tatcggaaca
     9841 tcagctaaaa ctattattaa acctattatt ccaaacaata atccttgaat aaaagttaaa
     9901 aaaacaaatt tattctgata ctcattagaa tgattccttt taaaggtcga gtaagcctga
     9961 cctaaaccaa ctccacctaa aatataaaaa atttctacta agttcattac ataggcataa
    10021 tctccttttt tttcaacacc taatccccta ttaattataa ttgaggataa aagtgttaat
    10081 aagattaaca aaaatttact cgttaaagca aaccaatatt tcttagatag tctcacttat
    10141 tttctccgta tgttaaattt tataacagta aatttaaaat tatagtatat tgaaatagaa
    10201 tatgaacaaa acgattaggg aatttaaagt aatttataaa aattctttag aagctgcatt
    10261 gtactactcc aacttcaaac cactatagta tcaaaaagta taccccacct ttttaaataa
    10321 actactcacc acccatttca tccaatggtg atatcaacac cattctattg ataaaaacaa
    10381 taaccaatgt tcccaatata gcatatttaa gtaatggaga taatatgtta gcaaaatcag
    10441 cacgagtaga ataaataaaa ataggtatca tatacagata tatcagcatc ccgtatatat
    10501 ttctttgagc gtttatataa agaaatctca tcaaaaagcc tgttagcata aaaatcatta
    10561 caattccaaa gtatcctcca ttcacatatc cctctcccac aagagtaaaa ccatatttgg
    10621 ttgaatgtac gtttggaaaa aaggtgtcca taaaccaagt ttgattagaa taccccgtat
    10681 tataaaaaat tcttactatg tcattaaaaa aagaacgacc ttcgaaataa ttgcccatat
    10741 tatgtaatat cagaatctgt aaattacgac tagctgatac aaactcacca tctagcaaat
    10801 caaaccaaat attatttgta tttatagatg aaacttgccc acttaataaa gtatatttaa
    10861 aaactgcaga taacggaatc agtagtgccg caagcggaac taacattaca agataaaaac
    10921 gttttatttt gtgaaagtaa aataatataa tcacatcaag gatgaataaa gtaaacatat
    10981 aatctctttc ccctgtaacg atagagaaga gacagataac tatcgctgtg ttagtattac
    11041 aatttagtag tctccatttt ttagtactca actgtataaa tagctgatat gtatgaatga
    11101 gaatcataaa ataaaccaaa gaaaatacta acattatcac aatattggca cctgaatata
    11161 tttccccttt atttctaaaa ccacttccta atagatatat aattgctact gttgtgataa
    11221 acgtattcat attattgaga aataataaat agttattgtt atttaggttt attttccttt
    11281 cgcttaacac aatggcttta gaaggtagag ttaacaacaa agttgccaaa gccagccatt
    11341 gcatgaaaat caaatctttt gtataaccat agtttatata ctccattcta tagagtagcg
    11401 ggtaagaaat agaataaata gtaaagaagc tactatacca cacataggga tgaaaaatat
    11461 taaatttcac aattatcatt gccataaaac ttaaaaaaat cattgaaaat aatggaattg
    11521 taacatcatt attttcactg cataaaatta aagtccctga aaaaactaca cctactagaa
    11581 gtattatttt attttttata tcatttgatt gtagactaaa cttcatttac ttttttcctt
    11641 taactaataa tttaaacgta atgcgtattc aaaaatttga ttggctatgt agtcagtttt
    11701 tatagcatat ttaatatatc gaaacggatt ttccatcgca ttttaatcta aaccatcaga
    11761 attatttaat tctcttctaa tttgagcaaa atagtcactt ctgcgtttat ttaatacact
    11821 cgaaagaaat ttttttgaga attcaaactg ttttatcacc atcttttcct tatccatact
    11881 aataaaatct ataatagatc ccgcaatcgc ttgtgaagag gatggagtaa atagacaatg
    11941 tggccccagc aactctggaa ttcctgcttt attagaccct atacaagggc aagcacggct
    12001 catagcttca attaccgcac gaggtaaccc ttcttgtaaa cttggttgta tatataaatc
    12061 aactttatcc aaatactcat aaatttgtga tgtagtcaat tcccctaaaa aatggattct
    12121 attcgctact cccaattcct ctgctttctt ttttaagaaa ctttgatcac catcacctgc
    12181 taaataataa tccaacaaaa taccttgtat ttctaatctc ttcattgctt ccaatacaaa
    12241 tctatggccc ttggctcgta cattcacaga tgctgttgtc attattgaaa ttttttgagg
    12301 attaaatttt ttcaacttat aaagacggct cttcaaagat ctattctcta cagaggtaat
    12361 attaacattt gaagcaacga tattagattt aatattagga tatctatctt gtaaatattt
    12421 ttctgtcacg tatatgcaat aattagcgtt ttttacaatt gatttagttt tggcgtatat
    12481 atatggagct aataattttc cctttaaact atgataccag taagaatccc aagcatcccc
    12541 cattatttct gtcagatacg gcttacctat cttcaatgcg tagtctgcag tttttgatcc
    12601 aattatagac ggaatacgaa caactattaa gtcgctatca atcattcctt caataatctt
    12661 atttttattt tgaccaaata gaacctgatg tagaccttct atagggataa atttattaat
    12721 aaagttcgct ttatgatatc cttcagggta tgattccacc ttctcataac gactacatag
    12781 tacaatctct ccaaatgctt tagcatagcg ctcataaata aaataagctt tcggttttaa
    12841 atatatttca tttttataga ttgtacatct aaattcagtc gctataaata ctttcataat
    12901 ttcatctccc ttgataaacg tttctgaata aatatagtat cagctggaat atcctttgtt
    12961 acaacacttc ctgctgcaac cacactattc tcaccaatac tcactccctt caagacaatg
    13021 ctgttagctc caatccaaac attttctcca atcataactg gggccgtctt aaattttttt
    13081 gctttcaatc cacctggaac actaacatca tagtcatgat catatataag tactccagga
    13141 ccacatttta ctccagattt aatatctatg tatttacgac aagctatcat acaattatta
    13201 ctcaaaaata catcatcaga aatcttgagt tttgctcctt ttctaacttt caatactccc
    13261 ccggcgttta ctctaatctt ttttcctaag attaatttag cattagattc ctgttcgaca
    13321 gttacattct ttccaaattt taaaaaataa tgaaaagtaa gatccttgtt tcgacacact
    13381 tttaataata tcaagcaaat atttgcacga agtaaaccaa caatattttt tataatccta
    13441 ttcatctaaa gctcctttta ttttatctaa ataagcatct ataataattt gacgagaaaa
    13501 atattgctct atatacattc tcccttgaag tcccatctct tttcgttttt cattttctag
    13561 acctaaaaaa acttccaata tagagactag ttcctcaaca tttccccctt gaaatatata
    13621 gcctgtctct ctatctttaa caatttcttt gcaacctgga ttatctgtcg taattaaaac
    13681 acgtcctgaa ctagcgtttt ctagtaatac attgctcatt ccttcaccat acacactggg
    13741 atggataatt gcatgggaac gggtaatatg aggtatcaca tctttttgtt gtcccaaata
    13801 ataaacgatt cctttttttt ctaagtcaca aattttaagt tcataattac tctctgtcgg
    13861 ttctataaag ccaataatat taaactctgt tttgggatat cgactcttaa taatttgggc
    13921 agcagccaga taagtatcta tacctttttc ttttaatatc ctaccaataa aattaaaaac
    13981 gattgtttct ccttgaattc catttccacc atttggatac tgttgcacag gatacttttc
    14041 aatgttcact cctgacccag gtatcagctt agagtcaccc aaaatcaagc caagagtttt
    14101 taacattttc atattatatt cattttgaaa aaaaacacaa tttgatttcc taaaagaaat
    14161 tctaaacagt aataacacca ggcttcttac acaagaaccc attgttaaga cactacctaa
    14221 acctgttacg ttatttatat attttattcc taaaattgtt gcagctaggc tagcatatac
    14281 atttggtttc acggtatatg tcaagactac atccggtcta tattttctca ataatcttat
    14341 ataactaaga aatagacgaa tatcttttaa agggtttatt cctcttctat caatagtaat
    14401 atcttcatac tcaaattgaa tagacttcat caactctatc ttatctccat aaggacatga
    14461 cactagcact tcatacccat actcaactag tgactctata acttcttttc gaaaacaata
    14521 gatatcatcg tcatgattag ttattaacat aatttttttc ttttgtaaat tcatcaaaat
    14581 aatcttccta aaatataatt aaccgctact ccattatcct ttacaactat cattttaaaa
    14641 atagtaattt tctataagta attgtttcca aattgtgaca ctttaaaatt ctatacacat
    14701 atagaactta caaactattt acgaccgtaa actccatact tatcaaccga gatatccaat
    14761 ttatttaaaa caactcccag gaacagtttc cctgtttgtt ctaattgttg tttcgctttt
    14821 tggacatcac gtttattcgc ctcacctgtt gctgttatca agatggacgc atcacacttt
    14881 tgagtgataa ttgccgcatc aataacaatt ccaataggtg gtgtatcaac aatgatataa
    14941 tcaaaatatt tacgcaatgt ttcaatcata tcattaaaat ttttactttg taacaaggct
    15001 gtagggtttg gtgatacaga tcccgattga actacaaata aattttcaat atttgtatca
    15061 cataaaccgt gagataaatc agctgtccca gataaaaatt ctgttagccc tgtaattttt
    15121 tcacgagatt taaaaaatcc tgacataact gaatttcgaa tatcgccatc gaacaaaaga
    15181 gttttatagc ctgcacgcgc aaatgacatt gctatattta cggaagtagt tgtttttcct
    15241 tcccccggat taacagaagt aacggaaatt acttttagtt tatctccgct caactgtata
    15301 tttgtacaca aggtattgta atattcttct gccttcttaa tgaactccag ttttttttgt
    15361 gctatttcta atgtcggcat ctctctctcc tatttcaact tacccaagtt tggtacaact
    15421 cccaaaagtg tcatctgcag tgcattttcg atatcttccg gacgtttcac acgagtgtcc
    15481 aaaagttcaa gaagaagaac tataacacta gttccaatca cccctgccaa aaaaccaatt
    15541 agtgtattgc gtttaatatt tggcgaagac ggtgatatcg ccggtcttgc ctcctccagt
    15601 gttgtcacat cagaaacacg agtaatactg ataatttttt gagcagctac ttctcttaaa
    15661 gagttagcga tacggcttgc ctcttcagga actcgatcac taactgaaac agagacaata
    15721 cgggtatcaa ctggtactgt tactttaatt ttattagcca aaccttttgg catcaaatct
    15781 agtttcaaat cagaaataac ttcctccaaa acatcctgcg ataggacaat ttcacgatag
    15841 tctttaacca agtatgctcc tgcctgcaag tcttgattgg ttaaaccagg cttctctccc
    15901 tgattacggt taactacata aatccgagtc gtactagtaa actcaggttt gataacaaaa
    15961 gtactgtagg caaaagcaac tgaagaagtt ataattgcca ctaataaaat gaccaacttt
    16021 cttttccata aagctctgaa tagttgcaat acatcgattt ccaaagtgtt ttgttccttc
    16081 atattttctc ctaaattaat tgatccatta taatttttct gggattatct acaaaaagtt
    16141 ctttcgcttt tttcgctcca tatttcttag caatgatatc atatgcctgt tgcatatatg
    16201 gaggtctact gtctaaattg tgcatgtcac ttgcaactac atgaactaaa tcacgttcca
    16261 aaaaataccg agctctcttt ttcatgaatt tatatttttc accaaagaac ttaggttttg
    16321 aaacatgata actatttatc tgagtatagc accccatatc aatcagttca cgaacacgtt
    16381 tttcgttatt ctctaaagca tcataacgtt caatatgagc aattactggc gtgattccca
    16441 acatcaaaat attgctcaat cccgtatgaa tctgacgata ggaagtatgc atgctaaact
    16501 caatcaaggc ataacgacta tcattaaggg taggaatttc ttttttttct agcttttcta
    16561 gagcatccag agtatagtat atctctgcgc cataagcaat gactaaatca tctgctactt
    16621 cttttgcaat ttcccgaacc tgaagaaagt tttctgctat cttctcttcc ggagtttcaa
    16681 acatgccctt gcgacggtga gaggtagaga caatggttct caccccctgc ctgtaggatt
    16741 ctgccaagag agccttgctt tcctctcttg acttgggacc atcatctaca tcaaagacga
    16801 tgtgcgaatg gatgtctatc attttatcta ccctccatca catcctgtat agctgcttta
    16861 actacagtta aactactatc atctatttcc atcacataga ggttactgtc tggcattgca
    16921 taagaaggaa gatccatccg acctgtccct tttaaatctt gagaatttac tttataattc
    16981 cctccacttt ccaactgagt attcactaaa tctatcatag tctcaatcgg tatatttgtt
    17041 tgaagagaat cctgcaatcc ttgaagaata ctactatagt ttttcaaaac ctctgtagaa
    17101 gttaacttct gaataattgc tacaatgacc ttttgttggt tgcgaccacg gtcacggtct
    17161 ccatcggtta gtgagtagcg ttcacgtaca aaacctaaag cttgctcaga gtctagatgg
    17221 acattcccta ctgggaaatg gaacttccca tgtagagctg aaaactcttg atcattatga
    17281 acatctaccc ctcccaataa gtcaatcatt ttcaagaaag aagtgaagtt caatcgcaca
    17341 tagtaattga tatccactcc atagagattt tctaaggtgt gaatggacga atcaactcca
    17401 taaatgcccg catgggttaa tttatctttt tgattatttc cactatctgc gattggtaca
    17461 taggcatcac gtggcgttgt ggtcaagagg attttcttgg tatctcgatt gacagtcatt
    17521 aggatattga catctgatcg cgacaccgaa ctaataggac cataggtgtc aattccacta
    17581 acatagatat tgaaagactg attcttagac gtcttaggag cctctacttt tttagtgaat
    17641 cccttggtat aaatcttttt tatcttcgat gcgtagtctg gatactctga ctcgatgata
    17701 ttttcaaaga cactatttag gacaatggcc ttagtctccc ctgcaatcaa actcttgtaa
    17761 gctgccaagt aagacgaact ctggttgacc gtcaaatcgg tattctgact tgacttgata
    17821 tcagctagta gtttttgaat attttcatta tcagtcccag tcggtgctgt cacactcgtc
    17881 agttgcgtaa cattttcgat cttactatct gctaaaacag cgacactgat tgaatattct
    17941 gagtaattag aagtcgcatt taaacgattg gtcagtccaa caaactgctg tactgcaaag
    18001 agcgacactg agctgacaag gatagagaac agcaacagaa aaatagtaaa cttttcagct
    18061 tttttataga taatcaagag tagccctacc aaggcaacta gtaggactaa cgcagttacc
    18121 actaggttaa gatatctaaa agcaaggata ttgtacttaa agattaagaa caataaaaaa
    18181 caaattaaca ataaataaat agtcagcaaa acgatattaa cacttcgctt cactttctgt
    18241 gaacgtgatt ttttaaaacg tctactcatg attaacacct ataccttgaa catcatacaa
    18301 ttatatcact tttttacggt aatgtctaca cctttatttt cactatctgc atctttaagt
    18361 atcttagtag acttcccgcg aaccaaaaat atagtaaaat gaaataagaa taggacaaat
    18421 caatcaggac agtcaaatcg atttctaaca atgttttaga atcagatgtg tactattcta
    18481 gtttcaatat aa
//
LOCUS       DAVBOG010000040        18308 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.040, whole genome shotgun sequence.
ACCESSION   DAVBOG010000040 DAVBOG010000000
VERSION     DAVBOG010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18308
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.040"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            166..480
                     /locus_tag="VQ865_001570"
                     /pseudo
     CDS             166..480
                     /locus_tag="VQ865_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996568.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
     gene            657..1316
                     /locus_tag="VQ865_001571"
     CDS             657..1316
                     /locus_tag="VQ865_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000793810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1868 domain-containing protein"
                     /protein_id="HET3135891.1"
                     /translation="MKNLTKIKFKENGEFNHFSGNTVVANLYTKQDLMEVVDIIQSRY
                     RELPFIDKFTLTPRNSIHMTVIELLCHENRETEFWSSNLPLDTPLQEIHDYFAKQLEI
                     FPLLDEEIHMRITEMGKQNILVEPADEASAKRLEEIRTYVSEKAGVCFPNHDRYQFHI
                     SIGYLRIPLTEEEEEEFTKVRAELTEILLEKIPTITVNRIDYTVFEDMRQFVPYHEKF
                     K"
     gene            1341..2408
                     /locus_tag="VQ865_001572"
     CDS             1341..2408
                     /locus_tag="VQ865_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HET3135892.1"
                     /translation="MKKMKVWSTVLATGVALTTLAACSGGSNSTTASSSEEKADKSQE
                     LVIYSNSVSNGRGDWLTAKAKEAGFNIKMVDIAGAQLADRVIAEKNNAVADMVFGIGA
                     VDSNKIRDQKLLVQYKPKWLDKIDQSLSDKDNYYNPVIVQPLVLIGAPDVKEMPKDWT
                     ELGSKYKGKYSIYGLQGGTGRAILASILVRYLDEKGDLGVSEKGWEVAKEYFANAYTL
                     QKGESSVVKALDKESPIQYGMIWGSGALIGQKEQNVEFKVMTPEIGVPFVTEQTMVLS
                     TSKKQALAKEFIDWFGQSEIQVEYSKKFGSIPANKDALKELPEDTKKFVDQVKPQNID
                     WEAVGKHLDEWVEKAELEYVQ"
     gene            2511..3521
                     /locus_tag="VQ865_001573"
     CDS             2511..3521
                     /locus_tag="VQ865_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135893.1"
                     /translation="MIKFDNIQIKYGDFVAIDNLNLDIHEGEFFTFLGPSGCGKSTTL
                     RALVGFLDPSSGSIEVNGTDVTHLEPEKRGIGIVFQSYALFPTMTVFDNIAFGLKVKK
                     VAPDVIKAKVSAVAAKIKISDQQLQRNVSELSGGQQQRVALARALVLEPKILCLDEPL
                     SNLDAKLRVDLRKELKRLQKELGITTLYVTHDQEEALTLSDRIAVFNNGYIEQVGTPV
                     EIYHNSQTEFVCDFIGDINVLTDETVHEVLLKNTSVFLEDKKGYIRLEKVRFNRETEQ
                     DFILKGTIIDVEFSGVTIHYTIKVSESQILNVTSIDSQAAIRSVGESVELFITPSDVL
                     QF"
     gene            3533..5224
                     /locus_tag="VQ865_001574"
     CDS             3533..5224
                     /locus_tag="VQ865_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HET3135894.1"
                     /translation="MRHKLNLKDWLIRLGLIWFLVTFIIYPNFDLVVNVFVKGGEFSL
                     DAVHRVLKSQRALQSIMNSFKLAFSLIITVNVVGILCVLFTEYFDIKGAKILKLGYMT
                     SLIYGGVVLATGYKFVYGPYGLITKFLQNVIPSLDSNWFIGYGAVLFIMTFSGTANHT
                     LFLTNTIRSVDYHTIEAARNMGAKPFTVFRKVVLPTLIPTLFALTIMVFLSGLSAVAA
                     PMIVGGKEFQTINPMIITFAGMGNSRDLAALLAIILGIATTILLTIMNKIEKGGNYIS
                     ISKTKAPLKKQKIASKPWNIIAHIVAYGLFTVFMLPLIFIVLYSFTDPVAIQTGNLTL
                     SNFTLENYRLFFSNSAAFSPFLVSFIYSIIAATTATILAVVFARVVRKHKSRFDFLFE
                     YGALLPWLLPSTLLAVSLLFTFNQPQFLVLNQILVGSLVILLIAYIVVKIPFSYRMVR
                     AILFSVDDEMEDAARSMGASPFYTMMKVIIPFILPVVLSVIALNFNSLLTDFDLSVFL
                     YHPLAQPLGITIRSAGDETATSNAQALVFVYTIVLMIISGTVLYFTQRPGRKVRK"
     gene            5227..5937
                     /locus_tag="VQ865_001575"
     CDS             5227..5937
                     /locus_tag="VQ865_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HET3135895.1"
                     /translation="MTATSLGLSNIEIVVRIVLSVVIGSIIGLERGSKSQPAGIRTYS
                     IVCLAACLIMMTNEYVSYKFGTGDPTRLGAQVISGVGFLGAGTILITDKKKITGLTTA
                     AGIWASAGIGLAIGVGFYEGALLVAISVWGVISMFQPLKKYLQNRSKMIELYIVVKST
                     EAYNRVLVYCAENGIRMTDSRTAFGDVNSDRIEYFDVPDKKIASFITLELSGRFEHLR
                     LMEEIANIVGVIYVEEIS"
     gene            6033..6224
                     /locus_tag="VQ865_001576"
     CDS             6033..6224
                     /locus_tag="VQ865_001576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135896.1"
                     /translation="MKDYKINFDLGKIEYFDNNCLIQVYKFISFYDICEMVFAFHLPP
                     DELITNVIFKEKINSMLKC"
     gene            6509..7510
                     /locus_tag="VQ865_001577"
     CDS             6509..7510
                     /locus_tag="VQ865_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000789954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HET3135897.1"
                     /translation="MKNINGKKVTIYDIARLSGFSPKTVSRVINGGVNVKEETYQAIQ
                     KVIEELSYIPNAYAKNLTKKEAINILISVKKIDSFPLIWFHTLLDKVLRTCKEFGVNA
                     IVEYFGEEDTISNSIISSTGSLVDGVIVFYESVDDIRIQYLKKNHMPFLVFGESQTSG
                     VVYVSNNNFQATYDMMKAVTEEKFKNMWLLMGGESHVNKDRERGVRSFLNDKNYFMDL
                     KVIYGLSTIDSVYSYAMQHLTTQNYPDIIFVSGDEKVQGLIRACYEKGILIPDDISII
                     GFDNIPISQYYTPALSTIAPNYVKLAKEMIEGVLAIIKGESVTSVEVSPKFVRRQSF"
     gene            8118..8192
                     /locus_tag="VQ865_001578"
                     /pseudo
     CDS             8118..8192
                     /locus_tag="VQ865_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829418.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            8651..10012
                     /gene="trpE"
                     /locus_tag="VQ865_001579"
     CDS             8651..10012
                     /gene="trpE"
                     /locus_tag="VQ865_001579"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HET3135898.1"
                     /translation="MERIIHGDVLSPILAYMRLKGQHKVILESIPRDKETARFSILAY
                     NPVFEIKFENGVLYQNGQVIDRDPLDFLYEVIHKSQHHSELPFGGGAIGFVGYDMISL
                     YEEIGQIPEDTIGTPDMHFFVYESYMVFDHKKEKIHVIEDALYSERSQEALEKSLNQV
                     LEELRIPAPNEFEDLDLSPLDFKPHIAPHKFEGMVETARDLIRNGDMFQCVLSQRFSA
                     EVTGNPFDFYRNLRVTNPSNYLYFYDFGDYQIIGASPESLVSVKNGIVTTNPIAGTRP
                     RGATDEEDKALATDLLSDEKETAEHRMLVDLGRNDIGRISETTSVQVTKYMEVELFRY
                     VMHLTSVVKGRLLPELTAMDALKATLPAGTVSGAPKIRAMRRIYELETEKRGVYAGAI
                     GYLSATGDMDLAIAIRTMILKNQRAYVQAGAGIVYDSIAQNEYQETINKAKSMTRIGE
                     LRP"
     gene            10009..10575
                     /locus_tag="VQ865_001580"
     CDS             10009..10575
                     /locus_tag="VQ865_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate/anthranilate synthase
                     component II"
                     /protein_id="HET3135899.1"
                     /translation="MILLIDNYDSFTYNLAQYIGNFAEVQVLRNDDSKLYEEAEKADG
                     LVFSPGPGWPVDAGKMEDMIRDFAGKKPILGICLGHQAIAEVFGGKLGLAPKVMHGKQ
                     SNINFEAPSVLYQGIEDDRAVMRYHSILIEEMPEDFEVTARSTDDQAIMGIQHKNLPI
                     YGFQYHPESIGTPDGLSSIRNFIEKVVK"
     gene            10586..11590
                     /gene="trpD"
                     /locus_tag="VQ865_001581"
     CDS             10586..11590
                     /gene="trpD"
                     /locus_tag="VQ865_001581"
                     /EC_number="2.4.2.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007517337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate phosphoribosyltransferase"
                     /protein_id="HET3135900.1"
                     /translation="MKEIIEKLAKFENLSGVEMTDVIERIVTGRVTEAQIASLLLALK
                     MKGETPEERTAIARVMRGHAQHIPTEIHDAMDNCGTGGDKSFSFNISTTAAFVLAGGG
                     IHMAKHGNRSISSKSGSADVLEALGINLDLKPAELGKVFDKTGIVFLFAKNMHPAMKY
                     IMPARLELGIPTIMNLTGPLIHPMALETQLLGISRPELLESTAQVLKNMGRKRAIVVA
                     GPEGLDEAGLNGTTKIALLENGEISLSSFTPEDLGMEGYAMEDIRGGNAQENAEILLS
                     VLKNEASPFLETTVLNAGLGFYANGKIDSIKEGVALARQVIARGKALEKLRLLQEYQK
                     "
     gene            11587..12354
                     /gene="trpC"
                     /locus_tag="VQ865_001582"
     CDS             11587..12354
                     /gene="trpC"
                     /locus_tag="VQ865_001582"
                     /EC_number="4.1.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011227478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="indole-3-glycerol phosphate synthase TrpC"
                     /protein_id="HET3135901.1"
                     /translation="MSQEFLARILEQKAREVEQMKLEQIQPLRQTYRLAEFLKNHQDR
                     LQVIAEVKKASPSLGDINLDVDIVQQAQTYEENGAVMISVLTDEVFFKGHLDYLREIS
                     SQVEIPTLNKDFIIDEKQIIRARNAGATVILLIVAALSEERLKELYDYATELGLEVLV
                     ETHNLAELEVAHRLGAEIIGVNNRNLTTFEVDLQTSVDLAPYFEEGRYYISESAIFTG
                     QDAERLAPYFNGILVGTALMQAENVAQRIKELQIDKG"
     gene            12341..12940
                     /locus_tag="VQ865_001583"
     CDS             12341..12940
                     /locus_tag="VQ865_001583"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HET3135902.1"
                     /translation="MTKVKICGLSTKEAVETAVSAGADYIGFVFAPSKRQVTLEEAAV
                     LAKLIPADVKKVGVFVSPSRVELLEAIDKVGLDLVQVHGQVADDLFENLPCASIQAVQ
                     VDGNGHVPNSQADYLLFDAPVAGSGQPFDWGQLDTTGLAQPFFIAGGLNEDNVVKAIQ
                     HFTPYAVDVSSGVETDGQKDHEKIRRFIERVKHGISGTK"
     gene            12918..14141
                     /gene="trpB"
                     /locus_tag="VQ865_001584"
     CDS             12918..14141
                     /gene="trpB"
                     /locus_tag="VQ865_001584"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HET3135903.1"
                     /translation="MAYQEPNKDGFYGKFGGRFVPETLMTAVLELEKAYRESQADPSF
                     QEELNQLLRQYVGRETPLYYAKNLTQHIGGAKIYLKREDLNHTGAHKINNALGQVWLA
                     KRMGKKKIIAETGAGQHGVATATAAALFNMECTIYMGEEDVKRQALNVFRMELLGAKV
                     EAVTDGSRVLKDAVNAALRSWVANIDDTHYILGSALGPHPFPEIVRDFQSVIGREAKQ
                     QYRDMTGQDLPDALVACVGGGSNAIGLFHPFVEDESVAMYGTEAAGLGVDTEHHAATL
                     TKGRPGVLHGSLMDVLQDAHGQILEAFSISAGLDYPGIGPEHSHYHDIKRASYVPVTD
                     EEALEGFQLLSRVEGIIPALESSHAIAFAVKLAKELGPEKSMIVCLSGRGDKDVVQVK
                     DRLEADAAKKGEAHA"
     gene            14134..14910
                     /locus_tag="VQ865_001585"
     CDS             14134..14910
                     /locus_tag="VQ865_001585"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HET3135904.1"
                     /translation="MPKTLTEKLNAIKAAGKGIFVPYIMAGDHEKGLDGLAETIHFLE
                     DLGVSAIEVGIPFSDPVADGPVIEEAGLRSLAHGTSTQALVETLKTIETEIPLVIMTY
                     FNPLFQYGVENFVKDLADTAVKGLIIPDLPHEHANFVEPFLADTDIALIPLVSLTTGI
                     ERQKELIEGAEGFVYAVAINGVTGKSGNYRADLDKHLAQLHQVADIPVLTGFGVSSQA
                     DLERFNAVSDGVIVGSKIVKALHQGEPIQDFIRQAVAYQK"
     gene            complement(14882..14983)
                     /locus_tag="VQ865_001586"
                     /pseudo
     CDS             complement(14882..14983)
                     /locus_tag="VQ865_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234126.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
     gene            15212..15352
                     /locus_tag="VQ865_001587"
     CDS             15212..15352
                     /locus_tag="VQ865_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000934013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135905.1"
                     /translation="MLNQDLFDSLEAQKIVDTLMKGQKDYVDERLEKRETMIVSNGYA
                     WT"
     gene            15389..15943
                     /locus_tag="VQ865_001588"
     CDS             15389..15943
                     /locus_tag="VQ865_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000464460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135906.1"
                     /translation="MFEYKLQLAGQTWGYLEFETNTEKYGKVLLIIKGKKRLTNQFPL
                     VQKNKSGYLFEYAQMNTLYLNQHSSYKNDEDSHSFPIQMELVSDEMIQEIEQATKNSN
                     IEKFMILTYEADSENNIISVDVVMPDARTGQLHLIQDLSEYIQSSSYHFEEAKYQDIP
                     NFSELSETEDFEIIPRIEKQEGQK"
     gene            15958..17109
                     /locus_tag="VQ865_001589"
     CDS             15958..17109
                     /locus_tag="VQ865_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000481741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HET3135907.1"
                     /translation="MFNGRVLKELRLLNGLSRAELAQRINLTEQAIWQFESNETKPKL
                     STKMHLANQFHVDLTYFEQEEESIRFDSSVIAFRNADLATRKTIDIQTMYLHKVDSLI
                     DYFESFVIIPNIIIHDLSNVVSESYHKGESIEELALYAREKLGISKDNHDLLYKLERS
                     GIYIVERLINGQADAYSAWSKLGRPYIVLGTNKSSVRRNFDLAHELGHILLHKYKDMN
                     EDGDRLEQEANYFASCFLLPKEEFLVKFEERVGKRVSNPDSYILLKSDLNVSIQALEY
                     RAFKLGLLTPKQHSYFYRQIAQKGYKMIEPLDDQIFVKKPSKVKSILDVVLSNHLVSL
                     ATIMSKQSIRLQFISEIFSVEMKFFDQYQEDRRTDRFDNIIPLYKRNNL"
     gene            complement(17161..17820)
                     /locus_tag="VQ865_001590"
     CDS             complement(17161..17820)
                     /locus_tag="VQ865_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HET3135908.1"
                     /translation="MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLR
                     PLDLIPILSQVFNRFRCRYCKVRYPVWYALFELGLGLLFLLYSWELLSLGQVVLITAG
                     LTLSIYDFRHQEYPLLVWMTFHLILIASSGWNLVMVSFLALGILAHFIDIRMGAGDFL
                     FLASCALVFSITELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLL
                     V"
     gene            17890..>18308
                     /locus_tag="VQ865_001591"
     CDS             17890..>18308
                     /locus_tag="VQ865_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000155432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135909.1"
                     /translation="MTIRFEEKVSIENAQFVCQWSNSLGKSFQEQWMGSRIPFLLTLQ
                     ALEEVFSIFDEQEFVGLIQKIRLEDSNLHIGRFFINPQKQGQGLGSQALRKFVSLAFE
                     NEDIDSISLNVFEANQRAQNLYQKEGFEIVQMVEAPVR"
BASE COUNT         5903 a         2959 c         3937 g         5509 t
ORIGIN      
        1 tactatatta tcgcttacca atatttgctt ttatatttgc taaactttca gaaaaaaagt
       61 tggagtatat gatgctaggt gactgcgtca tgttaataaa cgaaatggaa ataactgatc
      121 atagagtaga taacttattt gaaaaaggga aaaatgagat aaaagatcca tgtagtagat
      181 ttagcaatag gacatataaa agctttagaa aaagtatctg aaaaaacaga tgtttatatc
      241 tataacctag gctcgggaga aggcactagt gtattacaac ttgtaaatac atttgaaagt
      301 gttaataaga tccctattcc ttataaaata gttccaagac gttcaggaga cgttgcaatt
      361 tgttatgcaa atgcagacaa agcatataag gaattaaatt ggaggacaac aaaatcgatt
      421 gaagacatgt gtagagatac atggaattgg caatcaaaaa atcccaatga ctataattga
      481 tgatactgtc tatatgagtg ctgtattttg gaaaaattac ttaacctttt aatgaaatgc
      541 atatttaatg aaagataaat aaaaaaagtt tgacagcgct tgacaaagga aacggtttca
      601 ttgtataatg taaacatggt gacaccgatg tcaaatataa aaaagaaggt ctttatatga
      661 aaaacttaac aaaaattaag ttcaaagaga atggggaatt taatcatttc tctgggaata
      721 cagttgtagc aaatctttat actaaacaag atttgatgga agttgttgat attattcaat
      781 cacgttatag agaattacca tttatcgata agtttacttt aactccaagg aattctattc
      841 acatgactgt aattgaattg ttgtgccatg aaaatcgtga aacggagttt tggagcagta
      901 atcttcctct agatacacct ttacaggaaa tacatgatta ctttgctaaa caacttgaaa
      961 tttttccatt gttggatgaa gaaattcata tgcgtataac tgaaatggga aaacaaaaca
     1021 tactagttga acctgcagat gaagcttctg caaagagatt agaagaaatt cgtacttatg
     1081 tctcagaaaa agcaggtgtt tgtttcccta atcatgatag atatcaattc catatttcaa
     1141 ttgggtatct tcggattcct ctaaccgaag aggaggaaga agagtttact aaagtcagag
     1201 cagaattaac tgaaatttta ttagagaaga ttccaactat tactgtaaac cgtattgact
     1261 atactgtatt tgaagatatg agacaatttg ttccatatca cgaaaaattt aaataaaata
     1321 ataaaaaagg agaacttatc atgaaaaaaa tgaaagtttg gtctactgta cttgcaacgg
     1381 gagttgctct tactacactt gctgcttgct ctggaggttc aaattctacg actgcttctt
     1441 catctgaaga aaaagctgat aaaagtcaag aattagtaat ctattcgaac tcagtctcaa
     1501 atggtcgtgg tgattggtta actgctaaag caaaagaagc tggttttaat ataaaaatgg
     1561 ttgatatcgc tggcgctcaa ttagcagacc gtgttattgc tgagaagaat aatgcagttg
     1621 cagatatggt atttggaatt ggtgctgttg actcaaataa aattagagat caaaaattac
     1681 tagtacagta caagcctaaa tggttagata aaattgatca atctttatca gataaagata
     1741 attattataa tcctgtgatt gttcaaccat tagttttaat tggggcgcct gatgtaaaag
     1801 aaatgcctaa agattggact gaattaggta gtaagtataa aggtaaatat tcaatttatg
     1861 gtcttcaagg tggtacagga cgggcaattc tagcaagtat cttagttcgt taccttgatg
     1921 aaaaaggaga tttaggcgta tcagaaaaag gatgggaagt tgcaaaagaa tactttgcaa
     1981 atgcctatac tcttcaaaaa ggtgaaagct cagttgttaa agcgttagat aaagaaagcc
     2041 caattcaata cggtatgatc tggggttctg gagcgttaat cggacaaaaa gaacaaaatg
     2101 ttgaattcaa agttatgact cctgagattg gtgtaccatt tgtaactgaa caaactatgg
     2161 ttttaagcac tagtaaaaaa caagcgttag ctaaagaatt tattgattgg tttggtcaat
     2221 cagaaattca agtagaatat agtaaaaaat ttggctctat ccctgccaat aaagatgccc
     2281 taaaagagtt acctgaagat acgaaaaaat ttgttgatca agtgaaacca caaaatattg
     2341 actgggaagc tgttggaaag catttggatg aatgggtaga aaaagctgaa ttagaatacg
     2401 tacaataaga aataagagtt attttttatg tccaagtctc tctattattt ctaaatttat
     2461 ggaagaaata aagagaggct tttggtttag taatagaggg agttagtgag atgattaaat
     2521 ttgataatat tcaaattaaa tatggtgatt ttgttgcaat tgataatctg aatttagata
     2581 tacatgaagg ggaattcttt acatttcttg ggccttcagg atgtggtaaa tcaactactt
     2641 tgagagcatt ggtaggtttt ttagatccat catcaggaag tattgaagtt aatggaacag
     2701 atgtcactca tttggaacct gaaaagcgtg gaattggtat tgtatttcaa tcttatgcgc
     2761 tatttccaac tatgactgtt tttgataata ttgcatttgg tttaaaagtt aagaaggtag
     2821 ctccagatgt tattaaagct aaagtatcag cagtggcagc aaaaattaag atctctgatc
     2881 aacagttaca gcgtaatgta tcagaattat ctgggggtca acaacaaagg gtagcattgg
     2941 ctcgtgctct ggttcttgaa cctaaaattc tttgtctaga tgaaccattg tcaaaccttg
     3001 acgcaaaatt acgtgtagat ttgagaaaag agttgaaaag acttcaaaaa gagttaggta
     3061 ttactacttt atatgttact catgatcaag aggaagcctt gactttatct gatagaattg
     3121 cagtctttaa caatggatac atcgaacagg tcggtacacc agtagagatt tatcataatt
     3181 ctcaaactga atttgtatgt gattttattg gagatattaa tgttttgacc gatgaaacag
     3241 tccacgaagt attactgaaa aatacaagcg ttttcttaga agataaaaaa ggatacattc
     3301 gattagagaa agttcgattc aatcgtgaaa ctgaacaaga tttcattcta aaagggacaa
     3361 ttattgatgt tgagttttct ggagttacaa ttcactatac aataaaagtt tctgaaagtc
     3421 agattcttaa tgtaacaagt attgatagtc aggctgctat tagatctgtc ggagaaagtg
     3481 tggaattatt tatcacacca tcagacgttc tgcaatttta aggaggtgca gtatgcgtca
     3541 taaattaaat ttaaaagatt ggcttattcg tttagggtta atctggttct tagtaacatt
     3601 tattatttat ccaaactttg atctagtagt gaatgtattt gtaaaaggag gagaattttc
     3661 ccttgatgct gtacatcgtg ttctaaaatc tcagagggca cttcagagta ttatgaacag
     3721 ttttaagtta gcattttcac tcattattac agttaatgtc gtaggtattc tttgtgttct
     3781 atttacagag tactttgata ttaaaggtgc taaaatttta aaattaggtt atatgacctc
     3841 tttaatttat ggaggagtgg ttttagcgac tggatataaa tttgtctatg gtccttatgg
     3901 attgattaca aaatttttac aaaatgttat cccttcttta gactctaact ggtttattgg
     3961 gtatggtgca gtcttattca ttatgacatt ttcaggaact gctaatcata cattgttttt
     4021 aacaaataca attcgaagcg ttgactatca cactattgag gctgctcgaa atatgggagc
     4081 aaaaccattt actgttttcc gaaaagtagt gttaccaacc ttaattccaa ctctatttgc
     4141 acttactatt atggtttttc ttagtggttt atctgcagta gcagcaccca tgattgttgg
     4201 tggtaaagaa tttcaaacta taaatccaat gattattaca tttgcaggga tggggaattc
     4261 tcgtgattta gctgccttac ttgcaattat tttaggtatt gcaactacaa ttttgcttac
     4321 tatcatgaat aagatagaaa aaggtggaaa ttatatttct atctctaaga ctaaagcgcc
     4381 tcttaaaaaa caaaaaattg cgtctaagcc ttggaatatc attgctcaca ttgtagcata
     4441 tggattgttc acagttttca tgcttccact aatttttata gtattatact catttacaga
     4501 tccagttgca attcaaacag gtaacttaac attatcaaac tttactttag aaaattatcg
     4561 cttattcttt agtaatagtg cggcattctc tccattcttg gtcagcttta tttattctat
     4621 tattgctgcg acaacagcaa caattctcgc agttgtattt gctcgtgttg tcagaaaaca
     4681 taaatctcgt tttgatttct tatttgaata tggtgctcta cttccttggt tactaccaag
     4741 tacactttta gcagtaagtt tattatttac ttttaatcag ccacaatttc ttgtcttgaa
     4801 tcagattttg gtaggtagtt tggtaattct acttattgca tatatagttg taaaaatccc
     4861 attttcttat agaatggtac gtgctatttt atttagtgtt gatgatgaga tggaagatgc
     4921 agcaagaagt atgggtgctt caccttttta tactatgatg aaggttatca ttccatttat
     4981 tttaccggtt gttctctctg ttattgcttt aaactttaac tctttattaa ctgacttcga
     5041 cttatctgta ttcctttacc atcccctagc tcaaccatta ggtattacga ttcgatctgc
     5101 aggtgatgaa acagcaacat ctaatgcaca agctctggta tttgtttata caattgttct
     5161 gatgattatt tctggaacgg tattatactt cacacaaaga ccggggcgta aagtaaggaa
     5221 ataatcatga cagccactag tcttgggtta tcaaatattg aaatagttgt caggattgtt
     5281 ttatcagtag tcattggtag tataattggt ttagagagag ggagcaaatc ccagcctgca
     5341 ggcatccgaa cttatagtat tgtttgtcta gctgcatgtt tgattatgat gacgaatgaa
     5401 tacgtatctt ataaatttgg gacaggagat cctacacgat taggagctca agttatatca
     5461 ggtgtgggtt ttctaggcgc tggaacgatt cttattacag ataaaaagaa aattacaggt
     5521 ctgacaactg cagcaggcat ttgggcttcg gcaggaattg gattagctat tggagtaggt
     5581 ttttatgagg gagctctttt agtagctatt tctgtttggg gtgtgatatc catgttccaa
     5641 ccactaaaaa aatatctgca aaatcgttct aaaatgattg aattgtatat agtggttaaa
     5701 tctacagaag cctataatcg tgtattggtt tattgtgcag aaaatggtat cagaatgacc
     5761 gattcaagaa cagcgtttgg agatgttaat tctgacagaa ttgaatactt tgatgttcca
     5821 gataaaaaaa tagcgtcatt tattactctg gaattatcag gtagatttga acatcttcga
     5881 ctgatggaag aaattgctaa tattgtaggt gttatttatg tcgaagaaat tagctgaaat
     5941 ttagtaaaca aagggacaga tgtttttgtc cttttgtttt ttagatgttt taatcatcta
     6001 atttttgagt agatttttgc tcagaggttt ttatgaaaga ttataaaatc aattttgatt
     6061 taggtaaaat agaatatttt gataataatt gtttgataca agtatacaaa tttatttctt
     6121 tttatgatat ttgtgaaatg gtgtttgcct ttcatttacc tcctgatgag ttgataacaa
     6181 atgttatctt taaagaaaaa attaactcta tgttaaaatg ttaaattgac aggctattat
     6241 atgtttttat aaatcctaca cattttactg aaaaagttaa tctacaattt tatggtagtt
     6301 ttttctcata tgaatttatt tgtcgtgaag ttggaaacat tcttaaaaat aaaggtgtga
     6361 aatgcaattt aaactttttt gaagggaaag aatatttgta aaattaattt tgtgaatttg
     6421 tggatcttaa ataatttact aaattctctt gttaaaaaaa attaaatatt gtatagtaat
     6481 attagaatgt tcgtaatgga ggactgaaat gaaaaatata aatgggaaaa aggtaactat
     6541 ttatgatatt gcacgtttat caggtttttc tccaaaaaca gtttcacgag ttattaatgg
     6601 tggagtaaat gttaaagaag aaacttatca agcgattcaa aaagttatag aggaattgtc
     6661 gtatattcca aatgcgtatg caaaaaattt aactaaaaaa gaagctataa atatattgat
     6721 ttctgtaaaa aaaatcgact cttttccttt aatttggttt catacgctgt tagataaagt
     6781 gttacggacg tgtaaagaat ttggtgttaa tgctatagtt gagtactttg gagaggagga
     6841 tacaattagt aattcaatta tatcaagcac aggtagccta gtagatggtg ttattgtttt
     6901 ttatgaaagt gtagatgata tcagaattca gtatttaaag aagaaccata tgccttttct
     6961 tgttttcggt gaatctcaaa cgtctggagt agtctatgta tctaataata attttcaagc
     7021 tacttatgat atgatgaaag ctgtaactga agaaaaattt aaaaatatgt ggttgcttat
     7081 gggaggagaa tcccatgtta ataaggatcg tgaaagaggt gtgcgttctt ttctgaatga
     7141 taaaaattac tttatggatt taaaagtcat ttatggctta tctacaattg attcagttta
     7201 ttcttatgca atgcagcact tgactaccca aaattatccg gacattattt ttgtttcagg
     7261 agatgaaaag gttcaaggct tgattcgtgc gtgctatgag aaaggaattc ttattccaga
     7321 tgatatttct atcattggat ttgataatat tcctatttct cagtattata ctccagcttt
     7381 gtctacaatt gctcccaatt atgttaaatt ggctaaagaa atgatagaag gtgttttagc
     7441 aattattaaa ggggaaagtg tcacatctgt tgaagtttct cctaaatttg ttaggagaca
     7501 gagtttctag tattgtttaa ttcttgaaaa tcctagtgga aaagatggag tgttctaaaa
     7561 taagttctgt ttagcctcca ttcagtttct attgagttgg atccaatttc taacgagtgg
     7621 gacatgttca tgttcgatct aaggaagaca tggtcacatt cgaatgatat tttcaaaaaa
     7681 atcgtaaaaa agtcttgaca aagaaaaaac aaagtattaa aataagttca acaaatcaga
     7741 aaagtaacta tttttgatct tcagggagcc tgtggtgatt gtgaataggt ggttggaagt
     7801 agtgaaagtg ggctgatttt gaaaatgaat ttgaaacaat gaaaattcgg tgcgcacacc
     7861 ttacagtgca gcttgttgtt aaacaaggca gagatgtaaa gggatagtcc ctttataatt
     7921 gaggtggcac cgcgttacca acgccctcac acggaagtat attctgtgtg tgggcttttt
     7981 tctatccgtc gtttgcttta tcttttatta gggccttaac tcgctttgat gaacttgagt
     8041 tctatctaca gctccttgcc tcctactaaa agtaaacaaa aaggctggac taatacgaaa
     8101 aaagctagta atactcaatg aaaatcaaag agcaaactag gaaactagcc gcaggttgct
     8161 caaaacactg ttttgaggtt gcagatagaa ctgacgaagt cagtaaccat acctacgata
     8221 aggcgacgtt gacgcggttt gaagagattt tcgaagagta taaaggtgta ccgagatgaa
     8281 catctcttca tcaatgtctc tggtcgtgga ggcaaggacc tagctgcgat tgcagattac
     8341 tagaagctaa aaaataatag atggaaaaat tacagtcttt tctctcacag agagcttgtg
     8401 gttgctgaaa acaagcagag aaagctgtaa agttgggttc atctgaaacg agagaagaaa
     8461 acatcattct caagggagtg ccctttatcg cacagcctgt tacaggaggt atctgagaca
     8521 ggaatgagag ataggagaaa tcctataatt gaggtggcac cgcgaatttc gtcctcacgc
     8581 aagttatttt gcgtggggat ttttcataca gtcgccacga actagaatta gaactgaaag
     8641 ggaaattaca atggaacgaa tcattcatgg agatgtctta tcaccaatct tggcttatat
     8701 gcgcttaaag gggcaacata aggttatttt agagagtatt ccgagagaca aggaaacggc
     8761 tcgtttttct atcctagcct ataatccagt ttttgagatt aagtttgaaa atggagttct
     8821 ctatcaaaat ggtcaagtga ttgatcggga tcccttggat ttcctttatg aagtgattca
     8881 taagagtcag caccattcag agctcccttt tggtggtgga gccattggtt ttgtgggtta
     8941 cgatatgatt tcgctttatg aagaaattgg tcaaatccct gaggatacaa ttgggacgcc
     9001 agacatgcat ttctttgtct atgagagcta tatggtcttt gaccacaaga aggagaagat
     9061 acatgtcata gaggatgcac tttatagtga gcgcagtcaa gaggccttgg aaaaatcctt
     9121 gaaccaagtg cttgaggaat tacgcattcc tgctccaaat gaatttgaag acttggattt
     9181 atcaccactt gacttcaaac cgcatatcgc tccacataag tttgagggaa tggtagaaac
     9241 agctcgtgac ttgattcgta acggtgatat gttccaatgc gtactcagcc agcgcttctc
     9301 agcagaggtt actggaaatc catttgactt ctacagaaat ctccgcgtga ctaatccttc
     9361 taattacctt tatttctatg attttgggga ttatcaaatc atcggagcca gtccagaaag
     9421 tttggtttct gtcaaaaatg gcatcgtgac aaccaatccg attgcaggga cgcgaccaag
     9481 aggggctacg gatgaagaag acaaggcctt ggcgactgac ctcctctctg atgagaagga
     9541 aacagcagag catcgaatgt tagtagacct gggtcgtaat gatattggtc gcatctctga
     9601 aacgaccagt gtccaagtca ctaagtatat ggaagtggag ctcttccgtt atgttatgca
     9661 tctgaccagc gtggtcaagg ggcgtttgct tccagaactc actgccatgg atgccttgaa
     9721 agctacactt cctgctggaa ccgtttctgg agcaccaaag attcgtgcta tgagacgtat
     9781 ctatgaactg gaaacagaaa aacggggcgt atacgcagga gcaatcggct acttgtctgc
     9841 gacgggtgat atggatttgg ccattgccat ccgaaccatg attctcaaaa atcaaagagc
     9901 ctatgtgcag gctggggcag ggattgtcta cgactctatc gcccaaaacg aataccaaga
     9961 aaccattaac aaagcaaaat ctatgactag aattggagaa ctaagaccat gattttattg
    10021 attgacaact atgattcttt tacctataac ttggcccaat acattgggaa ttttgcagaa
    10081 gttcaggttc tgagaaatga tgattccaag ctgtatgaag aagctgaaaa agcagatggt
    10141 ctggtctttt ctcctggtcc tggttggcca gttgatgctg gaaagatgga agacatgatt
    10201 cgtgactttg caggcaagaa gccgattcta gggatttgtt taggccacca agccattgca
    10261 gaagtctttg gtggtaagct aggtttggct ccaaaagtca tgcatgggaa acagagcaat
    10321 atcaactttg aagcgccatc tgttttgtat caaggtattg aggatgaccg tgcggtcatg
    10381 cgttatcaca gtattttgat tgaggaaatg ccagaagact ttgaagtgac agctcgttcg
    10441 actgatgacc aagccatcat ggggattcaa cataaaaacc taccgattta tggcttccag
    10501 taccatccag agagcattgg aacgccagac ggcttgtctt ctattcggaa ttttatcgag
    10561 aaggttgtaa agtgaggaaa ctaggatgaa agagattatt gaaaaactag caaaatttga
    10621 aaatttatca ggtgtggaaa tgacggatgt cattgagcgt atcgtaactg ggcgtgtaac
    10681 tgaagcgcag attgcttctc tcctcttagc tcttaagatg aagggggaaa cacctgaaga
    10741 acgcacagcc attgcccgag tcatgagagg acatgcccag catattccaa ctgagattca
    10801 tgatgctatg gacaactgtg gtacaggtgg ggacaagtct ttcagtttta atatttccac
    10861 aactgcagcc tttgtcttgg ctggtggcgg tattcacatg gccaagcatg gtaaccgctc
    10921 gatttcttct aaatctggtt ccgcagatgt cctcgaagcc ttgggaatca atcttgacct
    10981 caaaccagct gaactaggta aggtctttga taaaactggc atcgtctttc tcttcgctaa
    11041 aaatatgcac ccagctatga aatacatcat gccagctcgt ttggaattgg gaattccaac
    11101 gattatgaac ttgactggtc cactgattca tccaatggct ttagaaacac agcttcttgg
    11161 aattagtcgt ccagaactcc tagaaagtac agctcaggtt ttgaaaaata tgggtcgcaa
    11221 acgtgccatc gtggttgctg gaccagaagg gttggatgaa gctggcttga acggaacaac
    11281 caagattgca cttcttgaaa atggcgaaat cagcttgtca agctttactc cagaggattt
    11341 gggaatggaa ggctatgcta tggaagatat tcgtggtggg aatgctcagg aaaatgcaga
    11401 aattttgctt agcgttctga aaaacgaagc aagtccattc ttggaaacga cagtcttgaa
    11461 tgctggtctt ggtttctatg ctaatggtaa gattgatagc atcaaggaag gagttgcctt
    11521 ggcccgtcaa gtgattgcta gaggcaaggc ccttgaaaaa ctcagactgt tacaggagta
    11581 ccaaaaatga gtcaggaatt tttagcacga atcttggagc agaaggcgcg tgaggtggag
    11641 cagatgaagc tggagcaaat ccagcctctg cgccagacct atcgcttggc agaatttttg
    11701 aagaatcatc aggaccgctt gcaggtaatc gctgaggtca agaaagctag ccctagtttg
    11761 ggagatatca atctcgatgt ggatattgtg caacaggccc agacttatga agaaaacgga
    11821 gcagtgatga tttcggtgtt gacagatgag gttttcttta aagggcattt ggattatcta
    11881 cgggaaattt ccagtcaggt agagattccg acgctcaaca aagactttat catagatgaa
    11941 aagcaaatca tccgcgctcg caatgcaggt gcgacagtta tcttgcttat tgtggcagcc
    12001 ttgtccgaag aacgcctcaa ggaactgtat gactacgcga cagagcttgg tctggaagtc
    12061 ttagtggaga ctcacaatct agctgaacta gaggtagccc acagacttgg tgctgagatt
    12121 atcggggtca acaaccgcaa cttgactacc tttgaggtcg acttgcagac cagtgtagat
    12181 ttagcccctt actttgagga aggtcgctat tacatttctg aatctgccat tttcacaggg
    12241 caggatgcgg aacgactagc cccatacttt aacggaattt tggtagggac agctcttatg
    12301 caggcagaaa atgtggccca gagaatcaag gagttgcaga ttgacaaagg ttaaaatttg
    12361 tggactatcg accaaagaag cggtggaaac agccgtttca gcaggagccg actatatcgg
    12421 ttttgtcttt gcacctagta aaagacaggt gactttagaa gaggcagctg tgttggcaaa
    12481 gcttattcct gcagatgtga aaaaggttgg agtatttgtt tcaccaagtc gggtagaact
    12541 gctggaagcg attgacaaag ttggcttgga cttggttcaa gttcacggtc aggtggcaga
    12601 tgatttattt gagaatttgc cttgtgccag tattcaggct gtgcaggtag atggaaatgg
    12661 gcatgtcccc aattctcagg cagattatct actctttgat gcccctgtgg caggaagtgg
    12721 ccagcccttt gattggggtc aactggatac gactggacta gcacagccct tctttatcgc
    12781 aggtggcctt aatgaagata atgtagtaaa agcaattcaa cattttactc cctatgcagt
    12841 agatgtatcg agcggagtgg agacagatgg acaaaaagat catgaaaaga ttagaagatt
    12901 tatagagagg gtaaagcatg gcatatcagg aaccaaataa agatggattt tacggaaaat
    12961 tcggcggacg ttttgtccca gaaacattga tgacagcagt tttggagttg gagaaggcct
    13021 accgtgaaag tcaggcagac ccaagtttcc aagaggaatt aaaccagctt ttgcgccagt
    13081 acgtaggacg tgaaactcct ctttattacg caaaaaactt gacccagcat atcggcggag
    13141 ccaagattta tctcaaacgg gaagacctta accatacagg agcccacaag attaacaatg
    13201 ccttaggaca agtttggctt gccaaacgca tgggtaaaaa gaaaattatc gcagaaacgg
    13261 gtgctggtca gcacggtgtg gcaactgcaa ctgctgcggc cctctttaac atggaatgta
    13321 ccatctacat gggtgaggaa gatgtcaaac gccaagccct caatgtcttc cgtatggagc
    13381 ttttgggagc taaggtcgag gccgtgacag atggttcgcg cgtgctcaag gatgcggtca
    13441 atgcagccct tcgttcatgg gtagctaata tcgatgatac ccactatatc cttggttctg
    13501 ccttggggcc tcatccattt ccagaaatcg ttcgtgactt ccaaagtgtc atcggtcgag
    13561 aggctaaaca acagtaccgc gatatgacag gtcaagatct gccagatgcc ctagtagcct
    13621 gtgttggtgg tgggtcgaat gctatcgggc tcttccatcc ctttgtagaa gatgagtcag
    13681 tagctatgta tggaactgaa gcagcagggc ttggtgtgga tacagagcac cacgctgcta
    13741 ccttgaccaa gggtcgtccg ggtgttcttc acggttctct catggatgtg ctccaagatg
    13801 cccatggtca aattcttgaa gccttctcta tctcagcagg tttggactat cctggtattg
    13861 gtccagaaca ttctcactac cacgatatca aacgtgccag ctatgtccct gtgacagatg
    13921 aagaagcctt ggaaggattc caactcttgt ctcgtgtgga agggattatc ccagccttgg
    13981 aatctagcca tgctatcgct tttgcggtga aattggccaa agaacttgga ccagaaaagt
    14041 ctatgattgt ctgcctatca ggtcgtgggg acaaggatgt ggttcaagtc aaagaccgct
    14101 tggaagcaga tgcagcaaag aagggagaag ctcatgccta agacactaac agaaaaattg
    14161 aatgctatta aagcagctgg aaaaggaatt tttgttccct atatcatggc tggtgaccac
    14221 gagaaaggtt tggacggtct tgctgaaaca attcactttt tagaagattt gggtgtctct
    14281 gcaattgaag tgggtattcc cttttcagac cctgttgcag atggacctgt tatcgaagaa
    14341 gctggcttgc gcagtttagc ccacgggacc tctacccagg ctttagttga aaccttgaaa
    14401 accattgaaa cagagattcc actggtcatc atgacctact tcaaccccct ctttcagtac
    14461 ggtgtggaga actttgtcaa agatctggct gatacagctg tgaagggctt gattatccca
    14521 gacttgcctc atgaacatgc caactttgta gaaccatttt tggcagatac agatatcgcc
    14581 ttgattcctt tagtaagctt gaccacagga attgagcgcc agaaagagtt gattgaaggc
    14641 gcggagggat tcgtctatgc cgttgccatc aatggggtga cagggaaatc aggcaattac
    14701 cgtgcagatt tggacaagca cttggcgcaa cttcatcaag tggccgacat cccagtcttg
    14761 acaggttttg gtgtatctag tcaagccgat ctggaacgct tcaatgcggt gtcagatggt
    14821 gttatcgtcg gttcgaaaat agtaaaagct ctccaccaag gagagccgat tcaggatttt
    14881 atcagacaag cagtagctta ccaaaaataa tcaaacaagt agcaagtaag aggaaaggca
    14941 cgaaaggaag tctttccttt ttcttttgca ggcgaaaggc tagttttata gtgaattgaa
    15001 tctggaatat tacactacgg ttcctaaaat attttaagaa agtgatttga atttcccaat
    15061 aaatttgttc agtttttaat tgattttact atagaagata taattttcta aattactctg
    15121 acacagaact ttaagaaaaa gctaattatt gtagtaattt ctttaagaaa atgatataat
    15181 tcattaaaaa gtatttggag gaggaagaat tatgttgaat caggatctct ttgattcgct
    15241 tgaggcacaa aaaattgtag atactttgat gaaagggcaa aaagattatg tagatgaacg
    15301 tctagaaaaa agagagacaa tgatagtgtc gaatggttat gcatggacgt gacctaatca
    15361 tattgatact gcatttgcat cagcagattt gtttgagtat aaattacaat tagcaggaca
    15421 gacttgggga tatttagaat ttgaaacaaa tacagaaaaa tatgggaaag tattgttaat
    15481 tataaagggt aagaagcgac ttacgaacca atttcctttg gtacaaaaaa ataagagtgg
    15541 ctacttattt gaatatgctc agatgaatac actttatctt aatcaacatt cttcctacaa
    15601 aaatgatgaa gatagtcatt cctttccaat tcagatggag ttagtttctg atgaaatgat
    15661 tcaagaaatt gaacaagcta ctaaaaattc gaatatcgaa aaatttatga ttttaactta
    15721 tgaggcggac tcagaaaaca atattatatc tgtagatgtt gttatgcctg atgcacgaac
    15781 tggtcagtta cacttgattc aagatttgtc tgagtatatt caatcaagtt cgtaccattt
    15841 cgaagaagct aaatatcaag atattcctaa tttttcagaa ttatcggaaa cagaagattt
    15901 tgaaattatt ccaagaatag aaaaacaaga aggtcaaaag tagtaaggag tatgtaaatg
    15961 tttaatggtc gggtattgaa agaattacgg ctgttaaatg gtttaagtag agcagaatta
    16021 gctcagagaa ttaatttaac ggaacaagcc atttggcagt ttgagtccaa cgaaacgaaa
    16081 cctaaattat caaccaaaat gcatttggcc aaccaatttc atgttgattt aacttatttt
    16141 gaacaggaag aagagagcat tcgatttgat tcttctgtaa ttgcctttag aaatgcagac
    16201 ctagcaacac ggaaaacaat agatattcaa actatgtatt tacataaggt agatagtttg
    16261 attgattatt ttgaaagttt tgtaattata cctaatatta taattcatga cctaagtaat
    16321 gtagtgagtg aatcttatca taagggagaa tccattgagg aattggctct ttatgccagg
    16381 gaaaaattag gtatttcaaa agataatcat gatttgcttt ataaattaga acgttcaggc
    16441 atctatatcg tggaacgatt aattaatggc caagctgatg cttatagcgc atggtcaaaa
    16501 ttgggaagac cttatattgt gttgggaacg aataaatcat ctgtacgtcg aaattttgac
    16561 ttagctcatg agctaggaca tattctttta cataaatata aagatatgaa tgaagatggc
    16621 gatcgtttgg agcaagaagc aaattatttt gcatcatgtt ttttattgcc aaaagaagag
    16681 tttttagtca aatttgaaga gagggttggc aagcgtgtca gcaatcctga tagttatatt
    16741 ttattgaagt cggatttgaa tgtttcgata caggctttag agtatcgagc ttttaagtta
    16801 ggattattga ctccaaagca acattcttac ttttatcgtc aaattgcgca aaaaggttac
    16861 aaaatgattg aacctttgga tgatcaaatt tttgttaaaa aaccaagcaa agtaaagagt
    16921 attctggacg tcgttttgag taatcatcta gtcagtctag cgactataat gtctaaacaa
    16981 agtattcgtt tacagtttat aagcgaaata ttttcagtcg aaatgaaatt ttttgatcag
    17041 tatcaagaag atagaagaac agatcgattt gataacatca tccctttgta caaaagaaat
    17101 aatttataat ttaactgtga aataatttca tgaaggacat atggcagaaa ttggacttta
    17161 tcaaacaagc agtagcttac caaaaataat caaacaagta gcaagtaaga ggaaaggcac
    17221 gaaaggaagt ctttcctttt tcttttgcag gagaaaggct aggatacccg tcgcagaagc
    17281 aaactgaatc aagatcagta actccgttat gctaaagacg agagcacaag aagctaaaaa
    17341 gaggaaatcc cctgcgccca tgcggatatc gataaaatga gccaaaattc caagagcaag
    17401 gaaggagacc atgaccagat tccagccaga ggaagctatt aggattaggt ggaaagtcat
    17461 ccagaccagt aagggatatt cctgatggcg aaagtcatag atgctcaagg tcaaaccagc
    17521 ggtgattagg acgacttgcc ccaaggaaag caattcccaa gagtaaagca gaaagaggag
    17581 tcctaagcct agttcaaaga gggcatacca gacaggatag cggaccttgc agtagcgaca
    17641 gcgaaagcga ttgaagacct gtgagagaat cggaatcaaa tctaagggac gcaagggagt
    17701 ctgacaggaa tcgcagtgac tggctgaact gataatggat tgctctggaa aacggtcaat
    17761 gaccaaacca agaaaggaag cgagaatgct cccgacgaga aaaaaataaa aatcaatcat
    17821 acttatctat tcgtaaaaaa tgggagaaat agtataatgg agaaacatag ataagatggt
    17881 gaggaaaaga tgacaattcg ttttgaagaa aaggtgagta tagaaaacgc tcaatttgta
    17941 tgccaatggt ccaactccct aggcaaatcc tttcaagaac aatggatggg atcaaggatt
    18001 ccttttctac tgacccttca agccttggaa gaagtctttt caatctttga tgaacaagag
    18061 tttgtgggac ttatccagaa aatcaggcta gaagacagca atcttcatat cgggagattt
    18121 tttatcaacc cccagaaaca ggggcaaggc ttaggtagcc aggctttaag gaaatttgtt
    18181 agtttggcct ttgaaaatga agatatagat agtatttctc taaatgtctt cgaggcaaat
    18241 caaagagctc agaatcttta ccaaaaagaa ggatttgaaa tcgttcaaat ggttgaagca
    18301 cctgtacg
//
LOCUS       DAVBOG010000041        18177 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.041, whole genome shotgun sequence.
ACCESSION   DAVBOG010000041 DAVBOG010000000
VERSION     DAVBOG010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18177
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.041"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ865_001592"
     CDS             complement(62..859)
                     /gene="proC"
                     /locus_tag="VQ865_001592"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HET3135910.1"
                     /translation="MKIGFIGLGNMGASLAKSVLQARPSDEILLANRSQVKVDAFIAN
                     FGGQTSNNEEIFEEADVIFLGVKPAQFSELLSQYQTILEKRESLLLISMAAGLTLEKL
                     ASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDSELFCQLLAKAGLLVELGES
                     LINAATGLAGCGPAFVYLFIEALADAGVQTGLPRETALKMAAQTVVGAGQLVLESQQH
                     PGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQELGK"
     gene            complement(863..2125)
                     /locus_tag="VQ865_001593"
     CDS             complement(863..2125)
                     /locus_tag="VQ865_001593"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HET3135911.1"
                     /translation="MVSRQEQFEQVQAVKKSINTASEEVKNQALLAMADHLVAATEEI
                     LAANALDMAAAKGKISDVMLDRLYLDADRIEAMARGIREVVALPDPIGEVLETSQLEN
                     GLVITKKRVAMGVIGIIYESRPNVTSDAAALTLKSGNAVVLRSGKDAYQTTHAIVTAL
                     KKGLETTTIHPNVIQLVEDTSRESSYAMMKAKGYLDLLIPRGGAGLINAVVENAIVPV
                     IETGTGIVHVYVDKDADEDKALSIINNAKTSRPSVCNAMEVLLVHENKAASILPRLDQ
                     MLVAERKEAGLEPIQFRLDSKASQFVSGQAAETQDFDTEFLDYVLAVKVVSSLEEAVS
                     HIESHSTHHSDAIVTENAEAAAYFTDQVDSAAVYVNASTRFTDGGQFGLGCEMGISTQ
                     KLHARGPMGLKELTSYKYVVTGDGQIRE"
     gene            complement(2135..3265)
                     /locus_tag="VQ865_001594"
     CDS             complement(2135..3265)
                     /locus_tag="VQ865_001594"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004240022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HET3135912.1"
                     /translation="MNNRSETMKYKRIVFKVGTSSLTNEDGSLSRSKVKDITQQLAML
                     HEAGHELILVSSGAIAAGFGALGFKKRPTKIADKQASAAVGQGLLLEEYTTNLLLRQI
                     VSAQILLTQDDFVDKRRYKNAHQALSVLLNRGAIPIINENDSVVIDELKVGDNDTLSA
                     QVAAMVQADLLVFLTDVDGLYTGNPNSDPRAKRLERIETINREIIDMAGGAGSSNGTG
                     GMLTKIKAATIATESGVPVYICSSLKSDSMIEAAEETEDGSYFVAQEKGLRTQKQWLA
                     FYAQSQGSIWVDKGAAEALSQHGKSLLLSGIVEAEGAFSYGDIVTVFDKESGKSLGKG
                     RVQFGASALEDMLRSQKAKGVLIYRDDWISITPEIQLLFTEF"
     gene            complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ865_001595"
                     /gene_synonym="pce"
     CDS             complement(3345..5228)
                     /gene="cbpE"
                     /locus_tag="VQ865_001595"
                     /gene_synonym="pce"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphorylcholine esterase CbpE"
                     /protein_id="HET3135913.1"
                     /translation="MKKKLTSLALVGAFLGLSWYGNVQAQESSGNKIHFINVQEGGSD
                     AIILESNGHFAMVDTGEDYDFPDGSDSRYPWREGIETSYKHVLTDRVFRRLKELGVQK
                     LDFILVTHTHSDHIGNVDELLSTYPVDRVYLKKYSDNRITNSERLWDNLYGYDKVLQT
                     ASEKGVSVIQNITQGDAHFQFGDMDIQLYNYENETDSSGELKKIWDDNSNSLISVVKV
                     NGKKIYLGGDLDNVHGAEDKYGPLIGKVDLMKFNHHHDTNKSNTKDFIKNLSPSLIVQ
                     TSDSLPWKNGVDSEYVNWLKERGIERINAASKDYDATVFDIRQDGLVNISTSYKPIPS
                     FQAGWHKSSYGNWWYQAPDSTGEYAVGWNEIKGEWYYFNQTGILLQNQWKKWNNRWFY
                     LTDSGVAAKNWKKIAGIWYYFNKENQMEIGWIQDKEQWYYLDVDGSMKTGWLQYKGQW
                     YYFAPSGEMKTGWVKDKEAWYYMDSTGIMKTGEIEVAGHHYYLEESGAMKQGWLKKAN
                     DWYFYKTGGSRAIGWIKDKDKWYFLKENGQLLVNGKTPEGYTVDSSGAWLVDVPIEKS
                     ATIKTTSHSEIKESKEVVKKDLENKETSQHESVTNSSTSQDLTSSTSQSSETSVNKSE
                     SEQ"
     gene            complement(5231..6118)
                     /locus_tag="VQ865_001596"
     CDS             complement(5231..6118)
                     /locus_tag="VQ865_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3135914.1"
                     /translation="MEIKIETGGLRLDKALSDLTELSRSLANEQIKSGQVLVNGQVKK
                     AKYTVQEGDVVTYHVPEPEVLEYVAEDLPLEIVYQDEDVAVVNKPQGMVVHPSAGHTS
                     GTLVNALMYHIKDLSGINGVLRPGIVHRIDKDTSGLLMIAKNDDAHLALAQELKDKKS
                     LRKYWAIVHGNLPNDRGVIEAPIGRSEKDRKKQAVIAKGKPAVTRFHVLERFGDYSLV
                     ELQLETGRTHQIRVHMAYIDHPVAGDEVYGPRKTLKGHGQFLHAKTLGFTHPRTGKTL
                     EFKADIPEIFKETLERLRK"
     gene            complement(6108..6569)
                     /locus_tag="VQ865_001597"
     CDS             complement(6108..6569)
                     /locus_tag="VQ865_001597"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HET3135915.1"
                     /translation="MKKRAIVAVIVLLLIGLDQLVKSYIVQQIPLGEVRSWIPNFVSL
                     TYLQNRGAAFSILQDQQLLFAVITLVVVIGAIWYLHKHMEDSFWMVLGLTLIIAGGLG
                     NFIDRASQGFVVDMFHLDFINFAIFNVADSYLTVGVIILLIAMLKEEINGN"
     gene            complement(6566..7474)
                     /locus_tag="VQ865_001598"
     CDS             complement(6566..7474)
                     /locus_tag="VQ865_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HET3135916.1"
                     /translation="MNIQQLRYVVAIANSGTFREAAEKMYVSQPSLSISVRDLEKELG
                     FKIFRRTSSGTFLTRRGMEFYEKAQELVKGFDIFQNQYANPEEEKDEFSVASQHYDFL
                     PPTITAFSERYPDYKNFRIFESTTVQILDEVAQGHSEIGIIYLNNQNKKGIMQRVEKL
                     GLEVIELIPFHTHIYLCEGHPLAQKEELVMEDLADLPTVRFTQEKDEYLYYSENFVDT
                     SASSQMFNVTDRATLNGILERTDAYATGSGFLDSDSVNGITVIRLKDNLDNRMVYVKR
                     EEVELSQAGTLFVEVMQEYFDQKRKS"
     gene            7467..7664
                     /locus_tag="VQ865_001599"
     CDS             7467..7664
                     /locus_tag="VQ865_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3135917.1"
                     /translation="MFIFYPQLLYLFIIPYFRSFPKRKKEHPILLNYLHYLPFSRQSY
                     FQNQFKKISGYTPLQYRKEKR"
     gene            complement(7716..8387)
                     /locus_tag="VQ865_001600"
     CDS             complement(7716..8387)
                     /locus_tag="VQ865_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3135918.1"
                     /translation="MKKRAIQILLALSLIFYKSTWFWRVFNHLAKPYLPASREFFQIL
                     LLMESGVLFLAVIYLLVFAGKKIFHFKWQLRYFIYLLLGYIISYMSDFLFSYFISLSS
                     NQISLNETVEMMGRQEFPYFLLIVCFIAPIAEELIYRGVLMTTFFKNSPWYGDVLLSA
                     IIFGYIHINFALTPLAFFIYASGGLILALLYRMTKNLYYPILVHILINITAFWDVWLL
                     LFSGS"
     gene            complement(8441..8662)
                     /locus_tag="VQ865_001601"
     CDS             complement(8441..8662)
                     /locus_tag="VQ865_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SP_0924 family bacteriocin-like peptide"
                     /protein_id="HET3135919.1"
                     /translation="MILMTKNINLTNEELELIQGGADPYGKNPNGRYDWEIEPVLTLP
                     VHGFCPRGTYDLGYIGGGNHLCKGSAARF"
     gene            8934..9743
                     /locus_tag="VQ865_001602"
     CDS             8934..9743
                     /locus_tag="VQ865_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000593565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3135920.1"
                     /translation="MIKLLALDMDGTLLNEAKEIPQAHIAAIHQAIEKGVKLVLCTGR
                     PLFGVLPYYKKLGLDLQNEYVIVNNGCSTHQTSDWGLVDWQELSPADIEYLYDLAEKS
                     DVQLTLFDESHYFVLGGKPNQVIENDAKLVFSDLTEISLEEATSGKLRMFQGMFLGTK
                     EQTDDFEQRFAEELCQRFSGVRSQPVIYEAMPLGTTKATALSRLAEILKIDSSEIMAM
                     GDANNDIEMLQFAGLGIAMGNASDYVKSLADAVTSSNEEDGVARAIEKYIL"
     gene            complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ865_001603"
     CDS             complement(9924..10799)
                     /gene="aguB"
                     /locus_tag="VQ865_001603"
                     /EC_number="3.5.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001246759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-carbamoylputrescine amidase"
                     /protein_id="HET3135921.1"
                     /translation="MRNVRVATIQMQCAKDVATNIQTAERLVRQAAEQGAQIILLPEL
                     FEHPYFCQERQYDYYQYAQSVAENTAIQHFKVIAKELQVVLPISFYEKDGNVLYNSIA
                     VIDADGEVLGVYRKTHIPDDHYYQEKFYFTPGNTGFKVWNTRYAKIGIGICWDQWFPE
                     TARCLALNGAELLFYPTAIGSEPILDTDSCGHWQRTMQGHAAANIVPVIAANRYGLEE
                     VTPSEENGGQSSSLDFYGSSFMTDETGAILERAERQEEAVLLATYDLDKGASERLNWG
                     LFRDRRPEMYRQITD"
     gene            complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ865_001604"
     CDS             complement(10809..11894)
                     /gene="aguA"
                     /locus_tag="VQ865_001604"
                     /EC_number="3.5.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatine deiminase"
                     /protein_id="HET3135922.1"
                     /translation="MMDSPKKLGYHMPAEYEPHHGTLMIWPTRPGSWPFQGKAAKRAF
                     TQIIETIAEGERVYLLVEQAYLSEAQSYLGDKVVYLDIPTNDAWARDTGPTILVNDKG
                     KKLAVDWAFNAWGGTYDGLYQDYEEDDQVASRFAEALGRPVYDAKPFVLEGGAIHSDG
                     QGTILVTESCLLSPGRNPNLTKEEIENTLLESLGAEKVIWLPYGIYQDETNEHVDNVA
                     AFVGPAELVLAWTDDENDPQYAMSKADLELLEQETDAKGCHFTIHKLPIPAVRQVVTE
                     EDLPGYIYEEGEEKRYAGERLAASYVNFYIANKAVLVPQFEDVNDQVALDILSKCFPD
                     RKVVGIPARDILLGGGNIHCITQQIPE"
     gene            complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ865_001605"
     CDS             complement(11891..13018)
                     /gene="nspC"
                     /locus_tag="VQ865_001605"
                     /EC_number="4.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxynorspermidine decarboxylase"
                     /protein_id="HET3135923.1"
                     /translation="MKLEQVPTPAYVIDLAKLEANCRILQYVQEEAGCKVLLAQKAYS
                     LYKTYPLISQYLSGTTASGLYEAKLAREEFPGEVHVFAPAFKDADLEELLEIMDHIVF
                     NSERQLRKHGPRCREAGVSVGLRLNPQCSTQGDHALYDPCAPGSRFGVTIDKIPSDLL
                     DLVDGLHFHTLCEQGVDDLQTTLKAVEEQFGPYLHEVKWLNMGGGHHITREGYDVDLL
                     ISEIKRIRKTYNLEIYIEPGEAIALNAGYLATEVLDIVENGMEILVLDASATCHMPDV
                     LEMPYRPSLRNGFEAQEKAHTYRLSSNTCLTGDVIGDYSFENPVQIGDRLYFQDMAIY
                     SFVKNNTFNGIGLPSLYLMDEQGDCSLLKAFGYQDFKGRLS"
     gene            complement(13018..14277)
                     /locus_tag="VQ865_001606"
     CDS             complement(13018..14277)
                     /locus_tag="VQ865_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="saccharopine dehydrogenase family protein"
                     /protein_id="HET3135924.1"
                     /translation="MSRLLVIGCGGVAQVAISKICQDSETFTEIMIASRTKSKCDDLK
                     AKLEGKTSTKIETAALDADKVEEVIALIESYKPEAVLNVALPYQDLTIMDACLATGVH
                     YIDTANYEAEDTEDPEWRAIYEKRCKELGFTAYFDYSWQWAYQEKFKEAGLTALLGSG
                     FDPGVTSVFSAYALKHYFDEIHYIDILDCNGGDHGYPFATNFNPEINLREVSAPGSYW
                     EDGKWVEVEAMSIKREYDFPQVGQKDMYLLHHEEIESLAKNIPGVKRIRFFMTFGQSY
                     LTHMKCLENVGLLRTDTINFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGV
                     KDGVEKTIYIYNVCDHQECYAEVGSQAISYTTGVPAMIGTKLVMNGTWKQAGVYNLEE
                     LDPDPFMEALNEYGLPWVVVENPQMVD"
     gene            complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ865_001607"
     CDS             complement(14274..15134)
                     /gene="speE"
                     /locus_tag="VQ865_001607"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HET3135925.1"
                     /translation="MDLWFSEVHTPDVKLSLRTAKQLYAGKSEWQDIEVLDTPAFGKI
                     LILNGHVLFSDADDFVYNEMTVHVPMAVHPNPKKVLVIGGGDGGVAQVLTLYPELEQI
                     DIVEPDEMLVEVCREYFPDFAAGLDDPRVTIYYQNGLRFLRNCEDDYDIIINDATDPF
                     GHTEGLFTKEFYGNSYRALKEDGIMIYQHGSPFFDEDESACRSMHRKVNQSFPISRVY
                     QAHIPTSPAGYWLFGFASKKYHPVKDFDKEGWKKRQLFTEYYTANLHVGSFMLPKYVE
                     DILEEEEGKK"
     gene            15390..16105
                     /locus_tag="VQ865_001608"
                     /pseudo
     CDS             15390..16105
                     /locus_tag="VQ865_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809094.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(16071..17546)
                     /locus_tag="VQ865_001609"
     CDS             complement(16071..17546)
                     /locus_tag="VQ865_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000661022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HET3135926.1"
                     /translation="MKEVDQNQAPIYEALVKLRKKRIVPFDVPGHKRGRGNPELVELL
                     GEKCVGIDVNSMKPLDNLGHPISIIRDAEELAADAFGASHAFLMIGGTTSSVQTMILA
                     TCKAGDKIILPRNVHKSAINALVLCGAIPIYIEMSVDPKIGIALGLENDRVAQAIKDH
                     PDAKAILINNPTYYGICSDLKGLTEMAHEAGMMVLVDEAHGAHLHFTGKLPISAMDAG
                     ADMAAVSMHKSGGSLTQSSLLLIGEQMNPEYVRQIINLTQSTSASYLLMASLDISRRN
                     LALRGKESFEEVIELSEYARHEINAIGGYYAYSKELIDGVSVCDFDVTKLSVYTQGIG
                     LTGIEVYDLLRDEYDIQIEFGDIGNILAYISIGDRIQDIERLVGALADIKRLYSRDGK
                     DLIAGEYIQPELVLSPQEAFYSERKSLTLDESVGQVCGEFVMCYPPGIPILAPGERIT
                     REIVDYIQFAKERGCSLQGTEDPEVNHINVIKRKTNYKKSQ"
BASE COUNT         5331 a         4168 c         3325 g         5353 t
ORIGIN      
        1 agtttgaatt tgattttcga agagtatcaa ccaccataaa agaggcagat aaaactacct
       61 cttatttacc tagttcttgt gttcgtttat aggcttgatg aactgcatcc atgaccgttc
      121 ctcgaaaagc atgcgcttct aggcttgcta cgccagcaat agtcgaaccg cctggactac
      181 aaacttgatc tttcaaaact ccaggatgtt gctggctttc taggaccaat tgcccagctc
      241 ctaccacagt ttgggctgcc attttcaagg ctgtttctcg tggtaatccc gtctgaacac
      301 ctgcatctgc caaggcctca ataaagagat agacaaaggc tggtccacaa cctgcaagac
      361 ctgtcgctgc attgattaag ctttctccta attcaaccaa gagaccagcc ttggctaaaa
      421 gctgacaaaa gagctcactg tcctcagccc tgcaattagg agacaaggca taactaatca
      481 ctccttgccc gatagaagca ggggtattag gcatcatacg aataattcgg tgttggcttg
      541 ggataagact tgctagtttt tctaaggtca atccagctgc catcgaaatc aaaagaagac
      601 tttctctttt ttcaaggatg gtctggtatt gagaaagcag ttcagaaaac tgagcaggct
      661 taacacctag aaaaatcaca tctgcttctt cgaatatttc ttcattgtta gaagtctgac
      721 caccgaagtt agcgatgaaa gcatccacct tgacttgact acgattggca aggagaatct
      781 catctgacgg tctagcctgc aagacagact tggctaaact agcacccata ttccccaaac
      841 cgataaatcc aatcttcatc ccttactccc ttatctgtcc atcaccagtg accacatact
      901 tgtagctagt caattccttc aagcccatgg gaccacgcgc gtgcaatttc tgagtagaaa
      961 tccccatttc acaaccaaga ccaaattgtc ctccatctgt gaaacgagtt gaggcattaa
     1021 catacaccgc tgcagagtcc acttgatctg taaagtatgc tgcagcttca gcattttccg
     1081 tcacaatagc atccgaatga tgagtgctgt gggattcaat gtgcgaaacc gcttcttcta
     1141 aactgctcac aaccttaaca gcaaggacat agtctaaaaa ctcggtgtca aagtcttggg
     1201 tctcagctgc ttgacctgaa acaaactggc ttgctttgct atccaagcgg aattgaattg
     1261 gttccagtcc agcttcctta cgctctgcaa ccagcatttg atccaagcga ggaaggatgc
     1321 ttgctgcctt gttttcatga accagcagaa cctccatggc attacaaaca gaaggacgac
     1381 tggttttagc attgttgatg atagacagcg ccttgtcttc gtctgcatcc ttatccacat
     1441 agacatggac aatcccagtc cctgtctcga taacaggtac aatcgcattc tcaaccactg
     1501 cattgatcaa gccagctcct ccacgaggaa tgagaaggtc tagatagccc ttggccttca
     1561 tcatagcata actactttca cggctagtat cctccaccag ttgaatcaca tttggatgaa
     1621 tagtagtcgt ctccaagccc ttcttcaagg ctgtgacaat ggcatgggtt gtttgatagg
     1681 catccttacc actacgaaga acaaccgcat ttccactctt aagagtcaaa gcagccgcat
     1741 cagacgtcac atttggacgg ctttcataga taataccgat gacacccata gctacacgtt
     1801 tttttgtgat aaccaaacca ttttcaagct gacttgtttc taaaacttca ccgattggat
     1861 ctggtaaggc aaccacttca cgaattcctc ttgccatcgc ttctatacga tctgcatcca
     1921 aataaagacg atccaacatc acatctgaga ttttcccctt agccgctgcc atatcgaggg
     1981 cattagccgc taaaatttcc tcagtagcag ccactaagtg atcagccatg gctagcaagg
     2041 cttggttttt cacttcttca ctagctgtgt taatcgattt tttaacagcc tgtacctgtt
     2101 caaattgttc ttgtctactc accatagttt acctctaaaa ttctgtaaaa agtagttgga
     2161 tttcaggagt aatggaaatc cagtcgtcac ggtaaatcaa gacacccttg gctttttgag
     2221 aacgcaacat atcctccaaa gcagatgctc caaattgcac gcgtcctttt ccaagtgatt
     2281 ttccactttc cttgtcaaat actgtcacga tatcaccgta agaaaaggct ccttctgctt
     2341 caacgatacc agataagaga agactctttc catgttgaga gagagcttcc gcagcccctt
     2401 tatcaaccca aatagaacct tgactctgag catagaaggc aagccattgt ttctgggtac
     2461 gaagcccctt ctcttgagca acaaagtaag aaccatcctc ggtctcctct gccgcctcaa
     2521 tcatggaatc tgatttcaag gatgagcaaa tataaacagg aactcctgat tccgtcgcga
     2581 tagttgcagc cttgattttg gttaacatac ccccagttcc gtttgacgaa cctgctccac
     2641 cagccatatc aataatctca cgattgatgg tctcgattct ctccaagcgt ttggctcttg
     2701 gatctgaatt aggatttcca gtatagagac cgtccacatc tgtcaagaaa actaaaaggt
     2761 ctgcttggac catcgccgct acttgagcac ttagagtgtc attgtcccca accttgagct
     2821 catcaataac gacactatca ttctcattga tgataggaat tgccccacgg ttgagcaaaa
     2881 ccgacaaagc ctgatgggca tttttataac gacgcttatc cacaaagtca tcttgggtca
     2941 gcaagatttg tgcagaaacg atttgacgca agagaagatt ggtcgtatat tcttccaaca
     3001 aaagtccctg ccctaccgct gctgaagcct gtttatcagc aattttagtc ggacgctttt
     3061 taaatcctaa ggctccaaaa ccagccgcaa tggcacctga agacaccaaa atcaactcat
     3121 gaccagcctc gtgcagcata gccaactgct gggtaatatc ctttacctta ctacgtgata
     3181 aacttccatc ctcatttgtc agagaagaag tacccacctt aaagacaatc cgtttgtatt
     3241 tcatagtctc actccgatta ttcatattta tccattataa catgaataac aggaaataga
     3301 aaagagttga taggaaaaag aaggccctaa aaccttcttt tctactactg ttctgattcc
     3361 gatttgttta cactcgtttc agagctttgt gaagttgagg atgtcaaatc ttgactagtt
     3421 gaagaatttg taacactttc atgttgactc gtttctttat tttcaagatc ctttttcact
     3481 acttctttgg attcttttat ttctgaatga cttgtagttt taattgtagc agatttctcg
     3541 atcggaacat ccactaacca ggcaccactt gaatccacag tatagccttc tggtgtctta
     3601 ccattcacaa gtaattgacc attttctttc aagaagtacc atttatcctt gtctttaatc
     3661 caacctatag ctcgtgaacc acctgtcttg tagaaatacc aatcatttgc ctttttaagc
     3721 cagccttgct tcatagctcc tgattcttct agatagtaat gatgtccagc aacttctatc
     3781 tcacctgtct tcatgatacc agtagaatcc atatagtacc aggcttcttt atcttttacc
     3841 cagcccgttt tcatttcccc tgatggagca aagtaatacc attgcccctt atattgaagc
     3901 caacctgtct tcatagagcc atcaacatcc aaataatacc actgctcttt atcttgaatc
     3961 caaccaattt ccatctggtt ttctttgtta aaataatacc agattccagc gattttcttc
     4021 caatttttag cagcaacacc agagtctgtc aaatagaacc aacgattgtt ccattttttc
     4081 cattgattct gtaataagat acccgtttgg ttaaagtaat accattcacc cttaatttca
     4141 ttccaaccga cagcatattc tcctgtagaa tcaggcgctt gataccacca gtttccatat
     4201 gaactcttat gccaaccagc ttgaaaactt ggaataggct tgtaggaagt tgaaatgttt
     4261 actaaaccgt cttgtcgaat atcaaaaact gttgcatcat agtctttgct ggctgcgttg
     4321 attctctcaa ttcctcgttc tttgagccaa ttaacatact cactatcaac accatttttc
     4381 caaggtagac tatccgaagt ttgaacaatc aaactcggac tcaaattttt aatgaaatcc
     4441 ttggtatttg atttgttggt atcatggtga tgattaaact tcatcaaatc aacttttcca
     4501 atgagaggac catacttgtc ttctgctcca tgaacattat ctaagtcgcc cccaaggtaa
     4561 attttcttgc cattgacttt taccacacta atcaaggaat tggaattatc atcccaaatt
     4621 ttctttaatt cacctgatga atcggtttca ttttcatagt tatagagttg aatatccatg
     4681 tccccaaact gaaaatgagc atctccctgt gtgatgtttt gaataactga aacacctttt
     4741 tctgaagcag tctgtaaaac cttatcataa ccgtacagat tatcccatag acgttcagaa
     4801 ttagtaatac gattatcact atatttttta agatagactc ggtcaactgg ataggtagac
     4861 agtaattcat caacatttcc aatatggtca ctgtgggtat gggtcaccaa aataaaatca
     4921 agtttttgga cacccaattc cttcaaacga cgaaagacac ggtctgttag aacatgctta
     4981 taagacgttt caattccttc tctccatgga tagcgagaat cacttccatc tgggaaatca
     5041 taatcttctc ctgtatccac catggcaaaa tgtccattgc tttcaagaat aatcgcatca
     5101 ctgccacctt cttgaacatt gataaagtgg attttatttc ctgaactttc ttgagcctga
     5161 acattcccat accatgacaa acctaaaaaa gcgcctacaa gtgctaaact agttaatttc
     5221 tttttcattc ttactttctc aatctctcca gggtttcctt aaaaatttct gggatatctg
     5281 ctttaaattc caaggtctta cctgttctcg gatgagtaaa acctaaagtc ttggcatgaa
     5341 gaaattgtcc atgtcctttc aaagtcttgc gaggaccata gacctcatca ccagcgactg
     5401 gatggtcgat ataagccatg tggacacgga tttgatgagt gcgccctgtc tccagttgca
     5461 actctactaa gctataatcg ccaaagcgtt ccaagacatg aaaacgcgtc actgcaggct
     5521 tccctttagc aattacagcc tgtttcttac ggtctttttc actccggcca atcggcgctt
     5581 caattacacc acgatcatta ggcagatttc catgaacaat cgcccaatat ttgcggagag
     5641 actttttatc cttgagttct tgggcaagtg ctagatgcgc atcatcgttt ttagcaatca
     5701 tgagaagacc tgacgtatcc ttatcaatac ggtgaacaat tcccggacgc agaaccccat
     5761 tgataccaga caagtcctta atatgataca tgagggcatt gactagagtt ccactagtat
     5821 gaccagcact cggatgcaca accattccct gaggtttgtt aacgacagcc acatcctcat
     5881 cttggtagac tatttctagc ggaagatcct cagccacata ctctaatacc tctggttctg
     5941 gcacatggta agtgacgaca tcaccctctt ggactgtgta tttagctttc ttgacttgac
     6001 cattgaccaa gacctggcct gatttaattt gttcattcgc aagactgcgt gataattctg
     6061 tcaaatctga caaagcctta tccaaacgca gaccaccagt ttcaatttta atttccattt
     6121 atttcctctt ttagcattgc aatcaataaa ataatcactc caaccgtcag atagctatct
     6181 gccacattga aaattgcaaa gttgataaag tcaaggtgga acatatccac aacaaagccc
     6241 tgactggccc tgtcaataaa gtttccaaga ccacccgcga ttatcaaagt caaacccaag
     6301 accatccaga atgagtcctc catgtgttta tgtaaatacc aaatggcacc tatcacgaca
     6361 accagagtaa tgacagcgaa taacagctgc tgatcttgta agatagaaaa ggctgcacct
     6421 cgattttgca ggtaggtcaa gctaacgaaa ttgggaatcc aggagcgcac ttcacccagt
     6481 ggaatctgct ggacgatata ggatttgacc aactgatcca gcccaattaa aagcagtaca
     6541 atgactgcca ctattgctct ttttttcatg atttcctctt ttgatcaaaa tattcttgca
     6601 tgacttctac gaagagagtc ccagcttgac taagctccac ttcttcacgt ttaacataga
     6661 ccatgcggtt atctaggtta tccttgagac gaataactgt aatgccatta acactgtcac
     6721 tatctaaaaa tccagaacct gtcgcatagg cgtccgtccg ctccaaaata ccattcaagg
     6781 tggcacggtc tgtcacatta aacatctgtg agctagcgct ggtatcgaca aagttctctg
     6841 aataataaag gtactcgtct ttctcttgag tgaaacgaac cgttggtaaa tccgctaaat
     6901 cctccatgac taattcctct ttctgggcta aaggatgacc ctcacagaga taaatatggg
     6961 tatggaaagg aatcaattcg atgacctcca gacctaactt ttcaacccgt tgcataatcc
     7021 cctttttatt ttgattgttg aggtagataa tcccaatctc actatgccct tgcgccactt
     7081 catctaatat ttgaacagta gttgattcaa aaatacggaa gttcttatag tcaggatagc
     7141 gctctgaaaa ggccgtaata gttggtggta agaagtcata gtgctggcta gcaacggaaa
     7201 attcatcttt ttcttcttca ggattggcat actgattttg aaaaatatca aatcctttaa
     7261 ccaattcttg cgctttttca taaaattcca tcccacgacg ggtcaagaaa gtccctgagc
     7321 tggtccgacg gaaaatctta aagcccaact ctttttccaa atcacgaaca gaaatagaca
     7381 gactcggctg actaacatac atcttttcag cagcttcacg aaaagtacca ctattggcaa
     7441 tagccacaac atagcgtaat tgttgaatgt tcatcttcta cccccaactt ctttatcttt
     7501 tcattatacc atattttaga agttttccaa aaaggaaaaa agaacatcct attcttctta
     7561 actatcttca ctatctgcct ttctcacgcc aatcttattt tcaaaatcaa ttcaaaaaaa
     7621 taagtggcta cacaccactt cagtatcgga aagaaaaacg ttgactattt gtgaaaaaag
     7681 aaaatgccgg aaaattccga cattttttta gtaagctaac ttcctgaaaa taggagtaac
     7741 cacacatccc agaaggcagt gatattgatg agaatatgaa ctagtattgg atagtagaga
     7801 tttttagtca tgcgatacaa tagagctaaa ataagacctc cactagcata aatgaaaaaa
     7861 gcaagaggag ttaaagcaaa attgatatga atataaccga aaataatagc agaaagcaaa
     7921 acatctccgt accaaggtga gtttttgaaa aaggttgtca taagcacacc tcgataaatc
     7981 aattcctcag caataggggc gatgaagcaa acgatgagca agaaataagg gaactcctgt
     8041 ctccccatca tttctaccgt ttcattcaaa gaaatctgat ttgaagacag ggatatgaaa
     8101 tacgaaaaga ggaagtcaga catatatgaa atgatgtagc ccagtaaaag gtagatgaag
     8161 tacctcagct gccacttgaa atgaaaaatt ttctttcctg caaaaaccag tagatagatg
     8221 accgctaaga aaagaactcc gctctccatc aaaagcagaa tctgaaaaaa ttcacgactt
     8281 gctggtagat agggctttgc gaggtgattg aaaactctcc aaaaccaagt tgatttgtaa
     8341 aaaattaagg acaatgctag taaaatttga atagcccgtt ttttcatatt aaattctctg
     8401 ctttctccac ttgtttcttc atattactaa taaattttac ttaaaatctc gcagcacttc
     8461 ctttgcaaag atgattgcct cctccaatat atcctaaatc ataggtgcct ctgggacaaa
     8521 atccatgaac cggcagagtt aatactggtt ctatttccca atcgtaccta ccattaggat
     8581 ttttaccata tggatctgct ccaccttgta tcagctctaa ttcttcattt gttagattta
     8641 tattttttgt cattaaaatc atgatatatt tcctccatta ttcttcagat tagttgagta
     8701 atctgatact catacctact tacaaaaaaa ctattatatt aagttggttt tttaatttgt
     8761 ctagttgcaa cattgacaaa catagtatag catatctttg ccaaatatcc tcttcaaatc
     8821 atgaattgtc atcaaaacat cttaaactat aaaatcaatt agtctcaagc tttctatcaa
     8881 tttcttctcc aaaatatgct ataataatag caaaagataa agaaggaaga cctatgatta
     8941 aactactagc cttggatatg gatggaaccc tcctcaatga agccaaggaa atcccacagg
     9001 ctcacatcgc tgctattcac caagccattg aaaaaggtgt caaactggtt ctctgtacgg
     9061 gtcgccccct tttcggtgtc ctcccctact acaaaaaact gggactcgac ctccagaatg
     9121 agtatgtgat tgttaacaac ggttgttcaa ctcaccagac tagcgactgg ggcttggttg
     9181 actggcaaga acttagtcca gctgacatcg aatacctcta tgaccttgct gaaaagagtg
     9241 atgttcagtt gacacttttt gacgagtcac attattttgt tctcggtggc aaacccaatc
     9301 aagttattga aaatgatgct aaactagtat tttcagacct gactgaaatt tctcttgaag
     9361 aagcgactag tggaaagtta cggatgttcc aaggtatgtt tttaggaaca aaagaacaaa
     9421 cagacgattt tgagcagcgt tttgctgaag agctttgcca acgattcagt ggagttcgtt
     9481 cgcagcctgt catttatgaa gcaatgccgc ttggaacgac aaaggctact gctctttcac
     9541 gactagctga gattttgaag attgattcct cagagattat ggccatgggc gatgctaata
     9601 acgatatcga aatgctccag tttgcagggc ttgggattgc aatgggaaat gccagcgatt
     9661 atgtcaaatc tcttgcggat gccgttacct caagcaacga agaagacggc gttgcgcgtg
     9721 ctattgagaa atatattcta taaaaaagaa aagcaaatag acagaagtta ctgctatttg
     9781 cttttttgct aatattttaa aatacggact aatcaataga caagaatagc gaatcataaa
     9841 aatcgattta ctagatgcca tagtatctta tagttgctaa taagaagtta gtctagcaga
     9901 atgaatctct catttctccc acactaatct gtaatttgtc tatacatttc tggtcttcta
     9961 tctcgaaaca agccccagtt taggcgttca cttgctccct tgtctaggtc ataagtagct
    10021 aacagaacag cttcttcttg tctttcagct cgttctagaa tagctcctgt ttcatccgtc
    10081 ataaaggagg aaccgtagaa gtcaagactg gaactctgtc cgccattttc ctcactagga
    10141 gtaacctcct ctaaaccata acgattggct gcgatgactg gaacaatatt cgctgctgcg
    10201 tgcccttgca tagtacgttg ccagtgacca caactatctg tatccaaaat cggctctgaa
    10261 ccgatggctg ttggataaaa gagcaattct gccccattca gagcaagaca gcgggctgtt
    10321 tcggggaacc attgatccca acagataccg ataccaatct tagcatagcg agtattccag
    10381 accttgaaac cagtgttacc aggcgtgaaa tagaattttt cttgataata atggtcatct
    10441 ggtatgtggg tctttcgata aacgcccaac acttccccat ctgcatcaat gacggcaata
    10501 gagttataca agacattacc atctttttca tagaaactga ttggtaaaac aacttgtagt
    10561 tccttagcaa tcaccttaaa atgctgaatg gcagtatttt ccgctacaga ttgggcatac
    10621 tggtagtagt catactgacg ttcctgacag aaatagggat gttcaaacaa ctcgggcaag
    10681 agaataattt gggctccttg ctcagcagcc tgacgtacta aacgctctgc ggtttggata
    10741 tttgttgcca catccttagc gcattgcatc tgaatggttg caactcttac atttctcatc
    10801 tttttctcct attctggaat ttgttgggtg atacagtgga tattgccacc acctaagaga
    10861 atatctctgg ctggtattcc gacaacttta cggtctggga aacacttgct gaggatatct
    10921 aaggccactt ggtcgtttac atcctcaaac tgtggaacca agacagcctt gttggcgata
    10981 taaaagttta cgtaggaagc tgctagtcgt tcacctgcgt atcgcttttc ttctccttct
    11041 tcatagatgt agcctggcaa atcttcttct gtcacaactt gtcgaactgc agggataggc
    11101 aatttatgaa tggtgaagtg acaacctttt gcatctgttt cctgttctaa gagttcgaga
    11161 tctgcttttg acatggcata ctggggatca ttttcgtcat ctgtccaagc caaaacaagc
    11221 tcagcaggac caacaaaggc agcaacatta tcgacgtgtt cattggtttc atcctgataa
    11281 ataccataag gaagccaaat aactttttca gcaccaagac tttctaataa tgtgttttca
    11341 atctcctctt tagtcaggtt aggattgcga ccaggactaa gcaagcaact ttcagttacg
    11401 agaatagttc cttgaccatc gctatggatt gcgcctcctt ccagtacaaa aggtttagca
    11461 tcatagacag gccttcccaa ggcctcagca aaacgactgg ctacttggtc atcctcttca
    11521 taatcttgat aaagaccatc ataggtgcct ccccaagcat tgaaggccca atccacggct
    11581 aatttcttac ctttatcatt gacgagaatg gttgggccag tatcacgcgc ccaggcatca
    11641 ttggtgggaa tgtctaaata aacaaccttg tctccaagat aggattgggc ttcagataga
    11701 taggcctgct ccaccaaaag atagactctt tccccttctg ctatggtctc gatgatctga
    11761 gtaaatgctc ttttagcagc ctttccttga aaaggccatg atcctggtcg agtcggccat
    11821 atcatgaggg taccatgatg gggttcgtac tctgctggca tgtgatagcc taattttttt
    11881 ggactgtcca tcatgataat ctccctttaa agtcttgata gccaaaagct ttgagtaagc
    11941 tacagtctcc ctgttcgtcc atgagataga gacttggcaa tccaatacca ttaaaggtat
    12001 tatttttgac aaaagaataa atggccatgt cttgaaaata aagtctgtct ccgatttgga
    12061 ctggattttc aaaactataa tcaccaatca catcgcccgt cagacaggta ttagaagaaa
    12121 gtctgtaggt atgggctttt tcctgtgcct caaagccatt tctcaaagat ggacgatagg
    12181 gcatctcaag tacatcaggc atatggcagg tcgcagaggc gtctaaaacc aagatttcca
    12241 taccgttttc tacaatatct aatacctcag ttgctaaata acccgcatta agcgcaatgg
    12301 cttcaccagg ctcgatatag atttcaagat tgtaagtttt tcggatacgc ttgatttctg
    12361 aaatcagcaa atccacatcg taaccttctc ttgtaatatg atgaccacca cccatattga
    12421 gccattttac ctcatgtaag tagggaccaa actgttcttc tactgctttc aaagttgttt
    12481 gtaaatcatc tactccctgc tcgcaaaggg tatgaaaatg aagtccgtca accaaatcta
    12541 gcaaatcact cggaatcttg tctatagtaa ctccaaagcg agaacctggt gcacaagggt
    12601 catagagcgc gtgatctcct tgagttgaac actgagggtt gaggcgcaaa ccaacactga
    12661 caccagcctc tcgacaacgc ggaccgtgtt tacgcaactg tctctctgag ttaaagacga
    12721 tatggtccat tatctctagc aattcctcca agtctgcatc cttgaaagca ggcgcaaata
    12781 catggacttc accaggaaat tcttcccttg ccaatttggc ctcatagagt ccactagctg
    12841 tcgtacctga tagatactgg ctaatcaagg gataagtttt gtagagggaa tatgccttct
    12901 gggcaagcaa gaccttgcaa ccggcctctt cttgtacata ttgtagaatg cggcaattag
    12961 cttctaactt ggccaagtca ataacatagg ctggtgttgg tacttgttct aacttcatta
    13021 gtccaccatt tgtggatttt caaccacaac ccatggcaaa ccatactcat tcaaagcttc
    13081 catgaatgga tctggatcta actcctcaag gttatacact ccagcttgtt tccaagttcc
    13141 gttcatgact aattttgtcc caatcatggc tggaacgcct gtcgtgtatg aaattgcttg
    13201 tgacccgact tctgcatagc actcttgatg gtcgcaaaca ttgtagatgt agatagtctt
    13261 ttcaacgcca tctttgacac ctgtaaagat acatccaata ttggtttttc cgactgtacg
    13321 tggcccaaga ctggcaggat ctggaagcaa ggctttcaaa aattgaattg gaacaatttc
    13381 ttggccgtta aagttaatgg tatccgtacg aaggagtcca acattttcaa gacatttcat
    13441 gtgcgtcaag taagattgac caaaagtcat aaagaaacga atgcgtttga cacctggaat
    13501 gttcttggcc aatgattcga tttcttcatg gtgaaggaga tacatatctt tttgtccaac
    13561 ttgagggaaa tcatactcac gcttgataga catagcttcg acttcgaccc atttcccatc
    13621 ttcccagtaa gaacctggag cagaaacctc acggagatta atttctggat taaagttggt
    13681 tgcaaatgga taaccgtggt caccgccatt acagtctaaa atgtcgatat aatggatttc
    13741 atcaaaatag tgtttgaggg cataagctga aaagacacta gttacacctg ggtcaaaacc
    13801 agaaccaaga agagcagtca agcctgcttc tttgaatttc tcttgataag cccactgcca
    13861 tgagtagtca aagtaggctg taaaaccaag ttccttacaa cgtttttcgt agatagcacg
    13921 ccactcaggg tcttctgtgt cttctgcttc gtagttggct gtatcgatat agtgaacacc
    13981 tgttgccaaa caagcatcca taatggttaa atcttgataa ggcagagcta cattcaaaac
    14041 ggcttctggt ttgtagcttt caatcagggc aatcacttct tcaaccttgt cagcatcaag
    14101 tgctgcagtt tcaattttag tacttgtttt gccttctagc ttcgctttca agtcatcgca
    14161 ttttgacttg gtacggctag caatcataat ctctgtaaat gtttcgctat cttgacaaat
    14221 ctttgaaata gcaacttggg caacgccccc acaaccaata actagtaaac gactcatttt
    14281 tttccttcct cttcttctaa aatgtcctca acatacttgg gcaacataaa ggatcccacg
    14341 tgtaagtttg cagtgtagta ttctgtgaaa agctggcgtt ttttccaacc ttccttgtca
    14401 aaatctttga cagggtggta ttttttcgat gcaaatccaa acaaccaata gccagctggg
    14461 ctagttggaa tatgggcctg ataaacccga ctgattggaa aggattgatt gaccttgcgg
    14521 tgcatgcttc ggcaggccga ctcatcctcg tcaaagaagg gactcccatg ctggtaaatc
    14581 atgatgccgt cttccttcag agctcgataa ctattgccgt agaattcctt ggtaaagagt
    14641 ccttccgtat ggccaaatgg atctgtcgca tcgttgatga taatatcgta atcatcttcg
    14701 cagtttcgca aaaagcgtag cccattttgg tagtaaatgg taacacgagg atcatctagc
    14761 cctgcagcaa agtctgggaa atactcacga cagacctcga ccaacatctc atccggttcc
    14821 acgatatcga tttgttccag ttcaggatag agtgttaata cttgggcaac accgccgtca
    14881 ccacccccaa taaccaatac tttctttgga tttgggtgga cagccatggg aacgtgaacg
    14941 gtcatttcat tgtagacgaa atcatccgca tctgagaaca agacatggcc atttaaaatc
    15001 agtattttcc caaaagctgg cgtatccaag acttcgatat cctgccattc actttttcca
    15061 gcgtaaagtt gcttggctgt tctcagagac aatttgacat ctggagtatg aacttcagaa
    15121 aaccataaat ccatctattt ctccttatat tatatttagc gcagttagct actgccaaag
    15181 cccaagtggt atacttggaa taagccactg tggattagtt tattccctcc aatcgcttga
    15241 cgatttccga aaggctctaa ccacagtttt ttgtttcaat tggtaatgag tttgataacg
    15301 catagacgtt ttatctcgtc taaggtaaca agacaaaaaa ttcgtggata accaagtaga
    15361 cttgaaatac tacatctgga ggtactccca tgctttatgt gggcattgat gtcgctaaaa
    15421 ataaacacga tgttacagcc ttgaatgttc caggaaaaac tgttcttaaa ccactcactt
    15481 tttcaaataa taaagctggt tttgaactct tagatctgtc tcttcgacaa ctcaaccaag
    15541 actgtctcat cgctcttgaa aataccggac attatgcctt taatctactg aacttcctgc
    15601 atgaacaagg atataaagtt tacacctgca atcctttgct catcaaggaa tttgccaaat
    15661 cattatcact tcgcaagact aaaacggata agaaagacgc tcatggcatc gctcttaaac
    15721 ttctttctga ccccaatcgt gaacaatttc aacacgataa tcggcaagta gaactaaaaa
    15781 tactggctag acatattcat cgtctcaaga aaaacagtct gattggaaag tacaatacac
    15841 tcgttgtctt gatatcatct ttcctgagtt ggataaaatc gttggaaagc attcagaata
    15901 tacctaccaa ctcttgacac gctaccctaa tcctcagaaa aggattgagg caggatttga
    15961 taagctgata gaaattaagc gattgaccgc ttctaattca agggcttttt gccgtgctct
    16021 aaaatcatcg ccaaatcatc aaattgaaat aagaaatagt ttagataaaa ctattgactt
    16081 ttcttatagt ttgtctttct cttaataacg ttgatatgat tgacctctgg atcttccgtc
    16141 ccttggaggg agcaaccacg ttccttggcg aattggatat agtctacaat ttctcgtgta
    16201 atgcgttcac caggagccaa gataggaatc cctggaggat agcacatgac aaattctcca
    16261 cagacctgtc caacagactc atctaaggtc aaactttttc tctctgaata gaaggcttct
    16321 tgtggagaca gcaccaactc gggctgaata tattctccag ctattaagtc cttcccatct
    16381 cgtgaataga gtctcttaat atcagccaga gcaccaacca agcgctcgat gtcttggatg
    16441 cggtcgccga tggaaatata ggccaagata ttgccgatat caccaaactc gatctgaatg
    16501 tcgtattcgt ctcgcaagag gtcataaacc tcgatacctg ttaagcctat tccctgagtg
    16561 taaactgaca acttggttac atcaaaatca cagaccgaca caccatctat taactctttt
    16621 gagtaagcat agtaaccgcc aatggcattg atttcatgac gagcgtactc ggatagctca
    16681 atgacttcct caaacgactc tttaccacga agggccaagt tgcgacgtga aatatccaaa
    16741 ctagccatca ataagtaaga ggcagatgta gactgggtca ggtttataat ctgacgaacg
    16801 tactcgggat tcatctgctc cccgattaaa agaagcgaac tttgtgtcaa actcccacca
    16861 gacttatgca tggaaactgc tgccatatca gctcctgcat ccatagcaga aattggaagt
    16921 ttaccagtga aatgcaaatg cgctccatgg gcttcatcta ctaaaaccat catgccagct
    16981 tcatgagcca tttctgtcaa cccctttagg tctgaacaga tgccgtagta agtaggattg
    17041 ttgattagga tagccttagc atctggatgg tcctttatgg cctgtgctac tcggtcattt
    17101 tcaagaccta aagcgatacc aatcttagga tctacactca tctcgatata gatgggaatg
    17161 gcaccacata gaaccaacgc attgatagca gatttatgga catttcgtgg cagaataatc
    17221 ttatctcctg ccttgcaggt tgccagaatc atagtctgca ccgatgaagt tgttccacca
    17281 atcattagaa aggcatggct agctccaaaa gcatctgcag ccagctcctc tgcatcacga
    17341 ataatcgaaa taggatggcc taaattatcc aagggtttca tcgaattgac atcaatgcct
    17401 acacattttt ctcctaagag ttcgacaagt tctggatttc cccgtccacg cttgtgacct
    17461 ggaacatcaa agggaacaat ccttttcttg cgtaacttca ccaaggcctc ataaattggg
    17521 gcttggtttt gatctacctc tttcaaaaca tactcctttc aatattttta ggaccttatg
    17581 aaaactaagg aactaaaggt tgactcatga aaaaagagca ggttttcacc tgctctgcaa
    17641 tcttctgacg tgtttatttt ggtttctgtt gagtatgtct gttcccgatg tttcctaact
    17701 ctctagtagc aaatattacg tactttattg atcgtttcac aagatgacgt gtgctttcac
    17761 cacactaaaa atttatgaat taggacaagt gtcctaacat caacttataa aagtaggctt
    17821 ttaaccctat caataatgtg gcttttcaac cacgcttcgg cattcaaccc tgcctgtccg
    17881 taggcatttt ttactcgggt ttatatttgc tagaaaacat catctcattt tctaagcttt
    17941 attactatat catgttttta agaacttgta aagtattttt tgataaaaaa caaaaatata
    18001 atagattgaa actagaatag tacacttctg cttctaaaac attattagaa atagatttta
    18061 ctgtcctgat cgatttgttc tgttcttgtt tcattttact atatgttcgt aaatgaaagt
    18121 tctataatga agttagccac ccagccctcc taaaaattag atggttcaac tagctga
//
LOCUS       DAVBOG010000042        18138 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.042, whole genome shotgun sequence.
ACCESSION   DAVBOG010000042 DAVBOG010000000
VERSION     DAVBOG010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18138
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.042"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ865_001610"
     CDS             complement(<1..839)
                     /gene="lytB"
                     /locus_tag="VQ865_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3135927.1"
                     /translation="MNLGEFWYNKINKNRGRRLMKKVRFIFLALLFFLASPEGAMASD
                     GTWQGKQYLKEDGSQAANEWVFDTHYQSWFYIKADANYTENEWLKQGDDYFYLKSGGY
                     MAKSEWVEDKGAFYYLDQDGKMKRNAWVGTSYVGATGAKVIEDWVYDSQYDAWFYIKA
                     DGQHAEKEWLQIKGKDYYFKSGGYLLTSQWINQAYVNASGAKVQQGWLFDKQYQSWFY
                     IKENGNYADKEWIFENGHYYYLKSGGYMAANEWIWDKESWFYLKFDGKIAEKEWVYDS
                     HSQA"
     gene            complement(881..1867)
                     /locus_tag="VQ865_001611"
     CDS             complement(881..1867)
                     /locus_tag="VQ865_001611"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HET3135928.1"
                     /translation="MVLFSAQEQLYYKEKIMTTNRLQVSLPGLDLKNPIIPASGCFGF
                     GQEYAKYYDLNLLGSIMIKATTLEPRFGNPTPRVAETPAGMLNAIGLQNPGLEVVLAE
                     KLPWLEREYPNLPIIANVAGFSKQEYAAVSHGISKATNVKAIELNISCPNVDHCNHGL
                     LIGQDPDLAYDVVKAAVEASEVPVYVKLTPSVTDIVTVAKAAEDAGASGLTMINTLVG
                     MRFDLKTRKPILANGTGGMSGPAVFPVALKLIRQVAQTTDLPIIGMGGVDSAEAALEM
                     YLAGASAIGVGTANFTNPYACPDIIENLPKVMDKYGISSLEELRQEVKESLR"
     gene            complement(1830..2630)
                     /locus_tag="VQ865_001612"
     CDS             complement(1830..2630)
                     /locus_tag="VQ865_001612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004254684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HET3135929.1"
                     /translation="MNPTCKKRLGVIRLETMKVVAQEEIAPAIFELVLEGEMVEAMRA
                     GQFLHLRVPDDAHLLRRPISISSIDKANKQCHLIYRIEGAGTAIFSTLSQGDTLDVMG
                     PQGNGFDLSDLDEQNQVLLVGGGIGVPPLLEVAKELHERGVKVVTVLGFANKDAVILK
                     TELAQYGQVFVTTDDGSYGIKGNVSVVINDLDSQFDAVYSCGAPGMMKYINQTFDDHP
                     RAYLSLESRMACGMGACYACVLKVPESETVSQRVCEDGPVFRTGTVVL"
     gene            complement(2880..3260)
                     /locus_tag="VQ865_001613"
     CDS             complement(2880..3260)
                     /locus_tag="VQ865_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HET3135930.1"
                     /translation="MASKMLHTCLRVENLEKSIAFYQDAFGFKELRRRDFPDHAFTIV
                     YLGLEGDDYELELTYNYDHGPYVVGDGFAHIALSTPDLEALHQEHSAKGYEVTEPNGL
                     PGTTPNYYFVKDPDGYKVEVIREK"
     gene            complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ865_001614"
     CDS             complement(3318..3677)
                     /gene="rplT"
                     /locus_tag="VQ865_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019786714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HET3135931.1"
                     /translation="MARVKGGVVSRKRRKRILKLAKGYYGAKHILFRTAKEQVMNSYY
                     YAYRDRRQKKRDFRKLWITRINAAARMNGLSYSQLMHGLKLAEIEVNRKMLADLAVND
                     AVAFTALADAAKAKLGK"
     gene            complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ865_001615"
     CDS             complement(3729..3929)
                     /gene="rpmI"
                     /locus_tag="VQ865_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HET3135932.1"
                     /translation="MPKQKTHRASAKRFKRTGSGGLKRFRAYTSHRFHGKTKKQRRHL
                     RKASMVHSGDYKRIKAMLTRLK"
     gene            complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ865_001616"
     CDS             complement(3962..4492)
                     /gene="infC"
                     /locus_tag="VQ865_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HET3135933.1"
                     /translation="MKTIAKQDLFINDEIRVREVRLIGLEGEQLGIKPLSEAQALADN
                     ANVDLVLIQPQAKPPVAKIMDYGKFKFEYQKKQKEQRKKQSVVTVKEVRLSPTIDKGD
                     FDTKLRNARKFLEKGNKVKVSIRFKGRMITHKEIGAKVLAEFAEATQDIAIIEQRAKM
                     DGRQMFMQLAPATDKK"
     misc_feature    complement(4508..4639)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            complement(4805..5989)
                     /locus_tag="VQ865_001617"
     CDS             complement(4805..5989)
                     /locus_tag="VQ865_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000655955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135934.1"
                     /translation="MKDVSLFLLKKVFKSRLNWIILLLFASVLGVTFYLNSQTANSHS
                     LESRLESRIAANERAINENEEKLSQMSDTSSEEYQFAKNNLDVQKNLLTRKTEILTLL
                     KEGRWKEAYYLQWQDEEKNYEFVSNDPTASSGLKMGVDRERKIYQALYPLNIKAHTLE
                     FPTHGIDQIVWILEVIIPSLFVVAIIFMLTQLFAERYQNHLDTAHLYPVSKVTFAISS
                     LGVGVGYVTVLFIGICGFSFLVGSLISGFGQLDYPYPIYSLVNQEVTIGKIQDVLFPG
                     LLLAFLAFIVIVEVVYLIAYFFKQKMPVLFLSLIGIVGLLFGIQTIQPLQRIAHLIPF
                     TYLRSVEILSGRLSKQIDNVDLNWSMGMVLLPCLIILLLVGILFIESWGSSRKKEVFN
                     RS"
     gene            complement(5993..6580)
                     /locus_tag="VQ865_001618"
     CDS             complement(5993..6580)
                     /locus_tag="VQ865_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000939891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3135935.1"
                     /translation="MLQLTHVTLKTRQVILQDVDFTFKKGRVYGLLAINGSGKTTLFR
                     AISNLIPISSGNIAAPPSLFYYESIEWLDGNLSGMDYLRLIKNIWKSGLNLRDEIAYW
                     EMSDYISLPIRKYSLGMKQRLVIAMYFLSQAKCWLMDEITNGLDEYYRQKFFDRLAQI
                     DRQEQLVLLSSHYKEELVDVCDRVVTIHQGQIEEV"
     gene            complement(6613..6801)
                     /locus_tag="VQ865_001619"
     CDS             complement(6613..6801)
                     /locus_tag="VQ865_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001810030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135936.1"
                     /translation="MTVTKSYKYDWNTVWEYSTNYHDHQYAWIPSWSRYDSYSEYKVG
                     GGWNYGRYEVINYYSGGY"
     gene            complement(6980..9220)
                     /locus_tag="VQ865_001620"
     CDS             complement(6980..9220)
                     /locus_tag="VQ865_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HET3135937.1"
                     /translation="MLQWIKNFSIPLIYLSFLLLWLYYAIFSVSYFALLGFVFLLVCL
                     FIQFPWKSAGKVLVICGVFGFWFLFQTWQQSQVSQNLVDSVERVRILPDTIKVNGDSL
                     SFRGKSDGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFDYQGY
                     LKTQGIYQTLNIKRIQSFQKVGSWDIGENLSSLRRKAVVWIKMHFPDPMRNYMTGLLL
                     GHLDTDFEEMNELYSSLGIIHLFALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPF
                     SLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIVMPNFFLTAGGVLSC
                     AYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDL
                     VFLPLLSILFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLI
                     SLALVYDLRKNIKGLTVLSLLITGLFFLTKYPLENEITMLDVGQGESIFLRDVTGKTI
                     LIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDKENVGDL
                     SEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKVRSMTVGENLPIFGSQLEVLSPRK
                     MGDGGHDDTLVLYGKFLDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSS
                     SPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGINSKVYRTDQQGAIRFKGVDSW
                     KIESVR"
     gene            complement(9204..9854)
                     /locus_tag="VQ865_001621"
     CDS             complement(9204..9854)
                     /locus_tag="VQ865_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000387331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HET3135938.1"
                     /translation="MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTSVKETNLQ
                     AEVAAVSKDSSTGKEVNKEEKEEPVEQDLITVDVKGAVKSPGIYDLPVGSRVNDAVQK
                     AGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
                     SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD"
     gene            complement(9922..10491)
                     /locus_tag="VQ865_001622"
     CDS             complement(9922..10491)
                     /locus_tag="VQ865_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135939.1"
                     /translation="MESIFVKFAQYPSIETERLLLRPVTLDDAEAMFDYASDKGNTRY
                     TFPTNQSLEETKNNIAQFYLANPLGRWGIELKDNGKFIGTIDLHKIDPVLKKAAIGYI
                     INKKYWNQGLTTEANRAVIELAFEKIGMNKLTALHDKANPASGKVMEKSGMRFSHAEP
                     YACMDQHEKGRIVTRVHYVLTKEDYFANK"
     gene            10668..11779
                     /gene="ald"
                     /locus_tag="VQ865_001623"
                     /pseudo
     CDS             10668..11779
                     /gene="ald"
                     /locus_tag="VQ865_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253293.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alanine dehydrogenase"
     gene            complement(12146..12406)
                     /locus_tag="VQ865_001624"
                     /pseudo
     CDS             complement(12146..12406)
                     /locus_tag="VQ865_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003069408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TfoX/Sxy family protein"
     gene            complement(12409..12909)
                     /locus_tag="VQ865_001625"
     CDS             complement(12409..12909)
                     /locus_tag="VQ865_001625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000566985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135940.1"
                     /translation="MIDQLSKYYSCRILTEKDIPSILSLYESNPLYFQHCPPEPNFAT
                     VKEDMLCLPEGKAKADKFFVGFWNGSDLVAVMDFVYAYPDEETVFIGLFMVDQAYQRK
                     GIGSHIVTEALAYFAKNFRKARLAYVKGNPQSQHFWEKQGFKSIGCEVKQELYTVVIA
                     EQSLED"
     gene            complement(13089..14057)
                     /locus_tag="VQ865_001626"
     CDS             complement(13089..14057)
                     /locus_tag="VQ865_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HET3135941.1"
                     /translation="MKEHSIDIQLSHPDDLFHLFGSNERHLRLMEEELDVVIHARTEI
                     VQVLGEESACEEARQVIQALMALVNRGMTVGTPDVVTAISMVKNDEIDKFVALYEEEI
                     IKDNTGKPIRVKTLGQKLYVDSVKQHDVTFGIGPAGTGKTFLAVTLAVTALKRGQVKR
                     IILTRPAVEAGESLGFLPGDLKEKVDPYLRPVYDALYQILGKDQTTRLMEREIIEIAP
                     LAYMRGRTLDDAFVILDEAQNTTIMQMKMFLTRLGFHSKMIVNGDISQIDLPRNVKSG
                     LIDAQDKLKNIHQIDFVHFSAKDVVRHPVVAQIIRAYEYSTEVAHD"
     gene            complement(14143..14358)
                     /locus_tag="VQ865_001627"
     CDS             complement(14143..14358)
                     /locus_tag="VQ865_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HET3135942.1"
                     /translation="MRKSFYTWLMTERNPKSNNPKAILADLAFEEAAFPKHTDDFDEV
                     SRFLEEHASFSFNLGDFDSIWQEYLEH"
     gene            complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ865_001628"
     CDS             complement(14367..15221)
                     /gene="cvfB"
                     /locus_tag="VQ865_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001095444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding virulence regulatory protein CvfB"
                     /protein_id="HET3135943.1"
                     /translation="MNTNLASFIVGLIIDENDRFYFVQKDGQTYALAKEEGQHTVGDT
                     VKGFAYTDMKQKLRLTSLEVTATQDQFGWGRVTEVRKDLGVFVDTGLPDKEIVVSLDI
                     LPELKELWPKKGDQLYIRLEVDKKDRIWGLLAYQEDFQRLARPAYNNMQNQNWPAIVY
                     RLKLSGTFVYLPENNMLGFIHPSERYAEPRLGQVLDARVIGFREVDRTLNLSLKPRSF
                     EMLENDAQMILTYLESNGGFMTLNDKSSPDDIKATFGISKGQFKKALGGLMKAGKIKQ
                     DQFGTELI"
     gene            complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ865_001629"
     CDS             complement(15281..15838)
                     /gene="frr"
                     /locus_tag="VQ865_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006148672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HET3135944.1"
                     /translation="MANAIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRIHVEY
                     YGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVV
                     PALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDI
                     QKVTDDAVKHIDDMTANKEKELLEV"
     gene            complement(15847..16584)
                     /locus_tag="VQ865_001630"
     CDS             complement(15847..16584)
                     /locus_tag="VQ865_001630"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000013002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HET3135945.1"
                     /translation="MANPKYKRILIKLSGEALAGERGVGIDIQTVQTIAKEIQEVHSL
                     GIEIALVIGGGNLWRGEPAAEAGMDRVQADYTGMLGTVMNALVMADSLQQVGVDTRVQ
                     TAIAMQQVAEPYVRGRALRHLEKGRIVIFGAGIGSPYFSTDTTAALRAAEIEADAILM
                     AKNGVDGVYNADPKKDKTAVKFEELTHRDVINKGLRIMDSTASTLSMDNDIDLVVFNM
                     NQSGNIKRVVFGENIGTTVSNNIEEKE"
     gene            complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ865_001631"
     CDS             complement(16668..18002)
                     /gene="trmFO"
                     /locus_tag="VQ865_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000083696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate--tRNA-(uracil(54)-
                     C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO"
                     /protein_id="HET3135946.1"
                     /translation="MSQSYINVIGAGLAGSEAAYQIAERGIPVKLYEMRGVKSTPQHK
                     TDNFAELVCSNSLRGDALTNAVGLLKEEMRRLGSVILESAEATRVPAGGALAVDRDGF
                     SQMVTEKVVNHPLIEVVRDEITELPTDVITVVATGPLTSDALAEKIHALNNGDGFYFY
                     DAAAPIIDVNTIDMSKVYLKSRYDKGEAAYLNAPMTKQEFMDFHEALVNAEEAPLNSF
                     EKEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPDDYTGPRDGEFKTPYAVVQLRQ
                     DNAAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLEQT
                     YRSKKQPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKEESEVIFPETTAIGSLAH
                     YITHADSKHFQPMNVNFGIIKELEGERIRDKKARYEKIAERALADLEEFLTV"
BASE COUNT         5188 a         4136 c         3375 g         5439 t
ORIGIN      
        1 gcttgactat gagaatcgta gacccattct ttttcagcta ttttcccatc aaatttgaga
       61 taaaaccaag attccttatc ccaaatccat tcattggctg ccatgtagcc accagatttt
      121 agataataat agtgaccatt ctcgaaaatc cattctttat cagcatagtt tccattttct
      181 tttatgtaaa accaagattg gtattgtttg tcaaaaagcc aaccttgctg tactttggca
      241 ccactagcat tcacataagc ttgattaatc cactgacttg ttagtagata accaccggat
      301 ttgaaataat agtccttccc tttaatttgg agccattctt tctctgcgtg ctgtccatct
      361 gctttgatat aaaaccaagc atcgtattga gaatcataga cccagtcttc tattactttg
      421 gcacctgttg caccaacata ggaagttcct acccaagcat ttcttttcat ctttccatct
      481 tggtcaagat aataaaaggc tcccttgtct tctacccatt ctgatttggc catatagcca
      541 ccagatttga ggtaaaaata gtcgtcacct tgctttagcc attcattttc agtatagtta
      601 gcatctgctt ttatatagaa ccaagattga taatgagtat caaaaaccca ctcattcgct
      661 gcttgactgc catcttcttt cagatactgt tttccttgcc aagtaccatc actagccatt
      721 gcaccctctg gactagctaa gaaaaatagc agagctaaaa aaataaatct tactttcttc
      781 attaaccttc ttcctctgtt cttatttatt ttattgtacc aaaattctcc taaattcata
      841 ttacaaacta ataaaaaatc aagaacagat tgattgcagt ttacctcaga gactctttta
      901 cttcctgacg gagttcttcc agactgctaa taccgtattt atccatgact tttggtaaat
      961 tttcgatgat gtcagggcag gcataaggat tggtaaagtt agctgttcca actccgatag
     1021 cagatgcccc agccagatac atttctaggg cagcttcagc cgaatccact ccccccattc
     1081 caatgatagg caggtctgtt gtttgggcta cttggcggat gagtttgagg gctactggaa
     1141 agactgctgg acctgacatt ccacctgttc cattggccaa gattggtttt ctggttttga
     1201 ggtcaaagcg cattccaacc agagtattga tcatggtcaa gccacttgct cccgcatctt
     1261 ctgcagcttt tgcgacagta acgatatcgg tcacactcgg ggttaatttg acataaactg
     1321 gcacttctga ggcttccaca gctgctttca ccacatcata agccaaatct ggatcttgac
     1381 caatcaaaag tccatgatta cagtggtcaa cattgggaca agaaatattg agctcgatag
     1441 cttttacatt agttgccttg gaaatcccat gagaaacagc tgcatactct tgttttgaaa
     1501 aaccagctac attggcaata ataggaagat ttggatattc tctttccagc caaggtagct
     1561 tttcagccaa aacaacctct aaaccaggat tttgcaagcc aattgcattg agcataccag
     1621 caggcgtctc tgctactctt ggagttgggt tcccaaaacg tggttcaagg gttgtcgcct
     1681 tgatcataat agaacctaaa aggtttaaat catagtactt ggcatactct tgtccaaagc
     1741 caaaacaacc tgatgctgga ataatcggat ttttcaaatc caaaccaggt agagacactt
     1801 gtaatcgatt tgtagtcata attttctcct tataatacaa ctgttcctgt gcggaaaaca
     1861 ggaccatctt cacagacgcg ttggctgacc gtctcgcttt ctggtacttt tagaacacag
     1921 gcatagcaag ctcccatccc acaagccata cgagattcca gagataaata ggctcttggg
     1981 tgatcatcaa aggtttgatt gatatacttc atcattcctg gagccccaca cgagtaaaca
     2041 gcatcaaact gactatctaa atcattgata acaacggaaa catttccctt gatgccataa
     2101 gaaccatcat ctgtcgttac aaagacctga ccatactgag ccaattccgt tttcaaaata
     2161 acagcatcct tattagcaaa accgaggact gtcactactt tcactccacg ttcatgcaat
     2221 tccttggcca cctcaagcaa gggtggaaca ccaatcccac caccaacaag gagaacctga
     2281 ttctgctcat caaggtcaga caagtcaaaa ccatttccct gaggccccat cacatcaaga
     2341 gtgtctccct gacttaaggt tgaaaaaatt gcagtcccag ctccctcaat ccgataaatg
     2401 aggtgacact gcttgtttgc cttgtcaata gacgaaattg aaataggacg acgtaagaga
     2461 tgggcatcgt ccggtacacg cagatgaaga aattggcctg ctcgcatggc ttcaaccatt
     2521 tctccttcta ggactaattc aaagattgct ggcgcgattt cctcttgtgc aaccaccttc
     2581 atggtttcca accgaatgac acccaaacgc ttcttacatg tgggattcat aacttttcct
     2641 ccttaaattt taaggggacc agataaagaa aagaccttgc tagtgcaagg cctcagttaa
     2701 aatcgtacaa cacaagagag cacactcaaa aagtctcctc tagaaaattg cactattctt
     2761 ttatctgaca ccttgtgagt ctctctggac tccccttaaa ggttgaattt ttattagtat
     2821 actctttcag ctaaaaaaag tcaagtagaa aacgaatatt ctacttaact tgcacgaaat
     2881 tatttttcac gaatgacttc gaccttatat ccatcagggt ctttgacaaa gtaatagttt
     2941 ggtgtagttc ctggtagacc atttggctca gtcacttcat agccttttgc actgtgttct
     3001 tgatgaagtg cctcaagatc aggtgtactg agggcgatat gggcaaaccc atcaccaacc
     3061 acatacggac cgtgatcgta gttataagtc aactccaact catagtcatc accctcaaga
     3121 cctagataga caatcgtgaa ggcatggtct ggaaaatctc tgcgacgcaa ttctttaaaa
     3181 ccaaaagcat cttgataaaa tgcgattgat ttttcaagat tttctactcg taagcaagtg
     3241 tgtagcattt ttgaagccat atttttctcc tttattttta aaaagactgg acaatcctgt
     3301 tccagtctca tcagttgtta tttaccaagt tttgctttag ctgcatctgc aagagctgtg
     3361 aaagctactg catcgttaac agccaagtca gcaagcattt tacggttaac ttcgatctca
     3421 gccaatttca aaccatgcat caattgtgag tatgaaagtc cgttcatacg agctgccgca
     3481 ttgatacgag tgatccacaa tttgcggaag tcacgttttt tctgacgacg gtcacggtat
     3541 gcatagtagt aagagttcat tacttgttct tttgcagtac ggaacaagat gtgtttagct
     3601 ccatagtaac cttttgctaa tttaagaata cgtttacgac gtttgcgtga tacaacgcca
     3661 cctttaacac gtgccatgtt ttatttcctc caaatatttc ctagaattgt ttacttacag
     3721 tcaagctatt atttcaagcg agtaagcatt gctttgatac gtttgtaatc tcctgaatgc
     3781 accatagatg ctttacgaag atgacgacgt tgtttcttag tttttccgtg gaaacggtga
     3841 gaagtgtaag cacggaaacg tttaagtcca ccagaacctg tacgtttgaa acgtttagct
     3901 gatgcgcggt gtgttttttg ttttggcatg attttttctc ctttatttaa ctttctgaca
     3961 attatttttt gtcagtcgct ggcgccaatt gcatgaacat ttgacgtcca tccattttag
     4021 cacgttgttc gatgatggca atatcttgag ttgcttcagc aaactcggct aaaacttttg
     4081 caccaatctc tttatgggta atcatacgac ccttaaagcg aatagatacc ttaactttat
     4141 ttcctttttc aaggaactta cgtgcattgc gaagttttgt atcaaagtca cccttgtcaa
     4201 ttgttggact tagacgaact tctttcacag taacaacgct ttgtttttta cgttgttctt
     4261 tttgcttctt ctggtactca aatttgaact taccgtagtc cataattttt gcaacaggcg
     4321 gtttggcttg gggttgaatc aatactaggt caacattagc gttatcagcc aaagcttgcg
     4381 cttcactgag tggcttgatg cctagctgtt ctccttcaag accaatcaag cgaacttcac
     4441 gtacacgaat ctcatcattg atgaataagt cttgctttgc tatggttttc acctcttttg
     4501 ttttattaga gaaaaacaat agcggactcg taaatataca agcccgcacg ttatgatagc
     4561 gtttcttcga aacttttcat ccgtagggcc aggcaactta atgtcacaag gcgagaagct
     4621 ctcacttctg cttttctcaa cttctatatg ataccaagtt ttctagctct tgtcaagata
     4681 aaaagttatt ttttgaaaag tttgtgtttg tgtttgtatt ttggtttggt tttcgaatca
     4741 aaaagagaga atcaagttga ttccctctct atgttagttt ttccttaact tccttataag
     4801 aatgctaaga cctattaaaa acttcctttt tacgtgaact tccccagctt tcgataaata
     4861 gaatccccac tagcaaaagg ataatcaggc aaggaagtaa gaccatcccc atgctccaat
     4921 ttagatcgac attatcaatc tgcttagata atcttccaga taaaatctcc actgaacgca
     4981 agtaagtaaa gggaatcaga tgtgcaatcc tttgaagagg ctgaattgtt tggatgccaa
     5041 acaataagcc aacaatccca atgagtgaaa gaaagaggac aggcattttt tgcttgaaaa
     5101 agtaagcaat caagtacaca acttccacaa tgacgataaa ggctaagaaa gctaagagca
     5161 agccaggaaa taatacatct tgtattttcc caatagttac ttcttgattc actaagctat
     5221 aaattgggta gggataatct aactgtccaa aaccacttat cagacttccc actagaaaag
     5281 aaaagccaca gattccgata aacagcacag ttacatatcc cactccaact ccaagagagg
     5341 atattgcaaa tgtcactttt gaaacaggat ataagtgagc tgtgtccaga tgattttgat
     5401 atctttctgc aaatagttgt gttagcataa aaataatcgc aaccacaaac aagcttggga
     5461 tgataacctc taaaatccag acaatctgat caatcccgtg ggtcggaaac tccaaagtat
     5521 gtgcttttat gttcaaggga tacagggctt ggtaaatctt ccgttcgcgg tcaaccccca
     5581 tttttaagcc agagctagca gtcgggtcat ttgatacaaa ttcataattc ttctcttcat
     5641 cttgccactg cagatagtag gcttctttcc agcgcccttc ttttagtaaa gttagaattt
     5701 ctgtctttcg cgtcaaaaga tttttttgca cgtctaaatt atttttagca aactggtatt
     5761 cctccgagct ggtatcagac atttgggaga gtttctcttc attttcattg atagccctct
     5821 cgttggctgc aatgcgactt tccaacctgc tctccaagct gtgtgagttt gcagtctgac
     5881 tatttaaata aaaggtaaca ccgagtacag atgcaaataa aagtaagata atccagttta
     5941 aacgactttt gaaaactttc tttaacaaaa atagactaac atctttcata aactaaacct
     6001 cttctatctg cccctgatga atggttacta ctctatcgca gacatcaacc aactcttcct
     6061 tatagtggga acttaaaaga accagctgtt cttgtctatc gatttgtgct agcctatcaa
     6121 aaaacttctg tcgataatac tcatctaagc catttgtaat ctcatccatg agccagcatt
     6181 tggcctgact gaggaaatac atggcaatca ccaagcgttg cttcatgcct aaggaatact
     6241 tgcgaatggg aagactgata tagtcagaca tttcccaata ggcgatttca tccctcaagt
     6301 tcagacctga cttccagatg tttttgataa gacgaaggta gtccatccca cttaagtttc
     6361 catccagcca ttcaatactc tcataataaa ataaagaagg aggggctgcg atatttccac
     6421 tacttatggg aattaaattg ctaatggcac ggaacagggt cgtctttcca gagccattga
     6481 tagcaagaag accataaacc ctaccctttt taaaggtgaa atccacatct tgcaagatga
     6541 cttgtcgcgt ttttaaggtc acatgagtaa gctgcaacat atctagccct cctttttctc
     6601 actctttaag aattaatagc ctccgctgta atagtttatg acctcataac gaccgtagtt
     6661 ccagcctccg ccaactttat actcagaata gctgtcataa cgagaccatg acggaatcca
     6721 agcatactga tggtcgtgat agttggtact atattcccaa accgtattcc aatcatactt
     6781 gtaactttta gtgactgtca cagcagatac actggactga agaagaccaa tagattataa
     6841 actaactaat taaacgattt ttgctaattt ttaatgattt tatatcctca atattgaata
     6901 cgttttcatt ataccatttt tatcattatt atgcaacaaa tttttagttt atttcactaa
     6961 tctacaacat ttatccttcc tatcgaacac tttcgatttt ccaactatcc acccccttaa
     7021 aacgtatagc tccttgctgg tcagttcgat aaactttgct attgatacct tccagtcgtg
     7081 tcaatgtttc ctgatggggg agtttcattc gattgctctt tccaactgag ataagagtaa
     7141 gctctggttt gagtttttct agaaaggctg gacttgatga ttttttattt ccttgttggc
     7201 tagctttcaa aacatttact ttcaagtctg gatagtgctt cagcaagtcc ttctctcctt
     7261 tctcctccaa atttcccgtg aagagaaatt gcttatccaa gaatttccca tacagaacta
     7321 gggtatcatc gtgtcctcca tctcccattt tccttggaga tagaacttct aactgacttc
     7381 caaaaatggg caagttctcc cctactgtca tactacgcac ctttgtttga gtcgcctgta
     7441 gttctgccac aaattccttc tgtttcagac tgtcttttga tactagaatc tcccctacat
     7501 ggaaagcctt ggtcacctct gacaaatctc caacattctc cttgtccgtg ttagtcaaaa
     7561 ttagctggtc aatcttagct actcctcgac ttttgagata gggaatcaag gttcgctggg
     7621 cattgctggt cgtcatcttt tcttgccatt tttcgatttt cttataagat tctgccttac
     7681 cacctacatc tatgagaatg gttttcccag ttacatcccg taggaaaata ctttctcctt
     7741 gccccacatc cagcatggtg atttcatttt ccagtggata cttggtaagg aaaaagagac
     7801 ctgtaatcaa taaactcaat actgttaatc ctttaatgtt tttcctcaaa tcatagacca
     7861 aagccaagga aattaacaat aagattaaaa gccatgcgtt gggttgacca aagacaagcg
     7921 gtctccttgc cacctgcgag accaagcgaa taatgccctc taaccattca aagataaagt
     7981 tcagctgaat gactggatag agaaaggaaa ggacaaataa gatagacaag agcggtaaga
     8041 agaccaagtc aaaaagaaag gaaaagacaa aggtcaaaag gatagaccaa ggttgaaatt
     8101 ccgcaaaata gaaggataga atgggcaata tgcccaagga gatgactaga ctttcactag
     8161 taacagcctt gagcccctcc ccttctttgc tggtcatggt caggataaaa gcataagcac
     8221 aggacaagac tcctcctgct gtcaagaaaa agtttggcat gacaataaag aggacaagca
     8281 ccgtcaaggc aaaattatcc aagcccttaa ccccatgttg agccagtagc ttttgcaaga
     8341 gactgcgaat aaccgatgct gaaaatccag ttagtcccgc atagataagg gaaaagggat
     8401 aagtcagcca cttcaacttt tcttgtgtca agcccaatcg taaaagtagt ttcttaaatc
     8461 cgtccatgaa aaaccctacc tgcatacctg acaaggcaaa aaggtgaata attcctaaac
     8521 tggaataaag ctcattcatc tcctcaaaat cggtgtccag atgtcctagc aagagtcctg
     8581 tcatgtaatt gcgcataggg tctgggaagt gcatcttaat ccaaaccaca gcctttcgac
     8641 gtaaactgga caggttttca cctatatccc aactgccaac cttttggaat gactggattc
     8701 ttttaatatt gagtgtctgg taaattccct gagtcttcag atagccttgg tagtcaaagc
     8761 caccaaaatt tctctgccct tctggctccg aaagcttccc ttctagtcct atctcatgaa
     8821 ggtcagttaa agcttgaaag gcttctttct cctcctcgga ctggagttta taatagactt
     8881 ggaaagcacg accatcagac ttaccacgaa aggacagact gtcaccgtta accttaatag
     8941 tgtctggtaa aatccgtacc ctttcaacag aatccaccaa attttgactc acttgactct
     9001 gttgccaagt ttgaaacaga aaccagaagc caaagactcc acaaatcact agaactttac
     9061 ctgctgattt ccaaggaaat tggataaaga ggcagactag cagaaaaaca aaacccaaca
     9121 aagcaaaata ggatactgag aaaatggcgt agtaaagcca tagtaacaga aaactcaggt
     9181 aaattagggg aatagagaaa ttcttaatcc actgtaacat agtctttaag tttttctatg
     9241 gtcttggcac caatgccaga gaccttcttg agctcgtcta ctgacttgaa cttgccattt
     9301 gcctcacgat ggtcaataat gtcctgagct cgttttcctc ccagtccctt gacctgcttg
     9361 agttcttcca gactggcctt gttgagattg accttctttt ccttgcttgt tgaagaagct
     9421 gtccccgaac cagtctgttg actaactgct tcttctccct tagtaggaac gtaaaccaga
     9481 gcctcatcac taactttctg agctagattg agcgacttgc tgtctgcttg ctctgtcaag
     9541 ccaccagcct tctgaacagc atcattgact cgactaccta caggcaagtc ataaatccct
     9601 ggcgatttga cagcaccttt gacatctact gtgattagat cttgttcaac tggttcttcc
     9661 ttctcttcct tgttcacttc ctttccggtc gatgagtcct tggaaacagc tgcaacttca
     9721 gcctgcaaat tcgtctcttt gacagatgtt tgtggagctg gctttagcag gaaaaatccg
     9781 cctacaagca agcccagacc agtacagatg acgatgattt tatactcttt gattttctcg
     9841 ataattgctt ccatattttc tcctctctta gattattcgt aagaggaaga aaaaacagtc
     9901 gaaaaatttc ttttcaactg cttatttatt tgcaaaatag tcttccttgg tcaagacata
     9961 atgaactctt gtcacgattc ggcctttttc atgctggtcc atacaagcat atggttctgc
    10021 atgggaaaaa cgcatgcctg atttctccat gacctttcct gacgcgggat tagccttatc
    10081 gtgaagggca gtcaacttat tcatccctat cttctcaaaa gctagctcaa tcacagcacg
    10141 attggcttct gtcgttaatc cttgattcca atacttttta ttgataatgt agccaatagc
    10201 tgccttctta agaacaggat caatcttgtg taagtcaata gttccgataa acttgccgtt
    10261 atcttttaat tcaatccccc aacgtcccaa gggattagcc aagtagaact gagcaatgtt
    10321 attcttggtt tcttccaagc tttgattggt tggaaaagtg taacgtgtat tacccttgtc
    10381 cgaggcatag tcaaacattg cttccgcatc atccaaagtt acaggtctaa gcaataaacg
    10441 ctccgtttct atagacggat actgggcaaa tttcacaaat attgattcca tacttttccc
    10501 tccattagag cttgattttc actagtctag cataaaaaaa tttggatgac aagtttttct
    10561 tgatttttga agcggtttca tatacaatga aaccgtcaca tttttgattt atgaactgga
    10621 atgtgacaac caaaacaaga ccgtcaattg aaaggtaggt tatctcaatg ttaatcggaa
    10681 tcccaaaaga aattaaaaat aacgaaaacc gtgtcgccct cacacctgca ggtgttcata
    10741 gcttagttag tcgtggtcat cgtgtcctta tcgaaacaaa tgctggtctc ggttctggct
    10801 ttactgatgc tgactatcaa aagcaaggag ctgagattgt cgctactgct ggtgaagctt
    10861 gggcagcaga gttggttgtg aaagtaaaag aacctttaag ttctgaatac ggttacttgc
    10921 gcgacgatct tcttctcttc acctacttgc acatggccgc tgctccagaa ttagcagatg
    10981 ctatgttagc agcaaaaaca acaggaattg cctatgaaac tgttcgtgac aatcaaggac
    11041 aactaccgct cctcgttcct atgagtgagg ttgcaggtcg tatggctgtt caaatcggag
    11101 ctcacttcct tactaagcaa gctggtggct ctggtgttct acttggtggt gtaccaggtg
    11161 ttccaaaagg aaaagtaact atcatcggtg atggtgtcgt cggtacacat gctgcccgca
    11221 tcgcccttgg tcttggtgct caagtgacta ttttagatat tagtgccaag cgtctctcag
    11281 ttctagaaga agtctttgga agtcaaattc aaactattat atctaattca ttcaacattg
    11341 aagcaagtgt gagagatgct gatgtggtga ttggagccat tctcatccct ggtgcaaaag
    11401 caccggaatt ggtgacagat gagatggtca aacaaatgcg tccaggctct gtatcgttga
    11461 cgttgctgtt gaccaaggtg gcgttatcga aacagctgac cgtgtgacaa cgcacgatga
    11521 acccgtctat gaaaaacacg gtgttctcca ctatgccgtt gccaatatcc ctggtgcggt
    11581 tgcccgcact tcaaccatcg ccctaaccaa tgtcactctt ccttatatcg aagctttggc
    11641 tggcaaagga ttcgcacaag caatctctga agatgaaggc ttgcgtcaag gtgtgaccac
    11701 ttatcaaggt tacttgacta gcctaccagt tgctcaagga cttaatcgtg actacactga
    11761 tatcaatgat ttagtataaa ttttgaaaag aaaagggtga cttcgcaagt cctacccact
    11821 gtgctttgtg tcatcagcta ttacatcgtt ggtttattgt actgtatact ttgcaactgg
    11881 agactttcgt tccagactca attgtgcata agaaactcta aattgaataa agtcaacaga
    11941 gtttcgccca accacttcgt cttgtaatga caattatata aaccaaagga agctgagctc
    12001 tttagtccca gcttcttttt atatataaaa ttttacccgt gcaaagacag ggccttagca
    12061 gacttctttt ttacttcgtt cacccttgct ttttcttttt aggtttgggc gttggcagtt
    12121 ggttatacat agctaaaatc aggtcttata gaaacatctt attatcaagt tcttccactc
    12181 aaatcatttc tttggcacct ttgtatggaa actcaaaaga agattggtca atcttatcta
    12241 agactgcttg cacgggttta actaaaaagc gatcgtcata aatgccgcca ataatcttgc
    12301 cgcggaagta aagaatatac tccccaatca tggaacggta agtcacatca tctaatcctg
    12361 ataattgttc caaaacaaat tccaaatagt tcttacttga tgccatttct aatcttctag
    12421 gctctgttca gcgataacaa ccgtatagag ttcttgctta acctcgcatc caattgattt
    12481 aaagccctgc ttttcccaaa aatgctgaga ttgcggattt cccttaacat aagccaaacg
    12541 tgcctttcga aagttcttag caaaataagc tagtgcttct gtcacaatat gactaccaat
    12601 ccctttcctc tgataggctt gatcaaccat aaacaaacca ataaaaacag tctcctcatc
    12661 aggatatgca tagacaaaat ccataacagc cacaaggtca gatccattcc aaaatccaac
    12721 aaaaaactta tcagccttag ctttaccttc aggtagacaa agcatgtcct cttttacagt
    12781 tgcaaaattt ggctctggtg gacaatgctg aaaatacaga ggattacttt catataaaga
    12841 taaaatactt ggaatatcct tttcagttag tatcctacaa ctgtaatact tagatagttg
    12901 gtcaatcatc ttttcaaatt cctactttct tgcgccctgt gattatgaca caggaagatg
    12961 cactgatcgt catcagccac ataaaagttc tttccatcgt gcctaatcgt tgtctcaaac
    13021 ctttagccta tacaactgga ttttcctctc tcaaaagtat attcttttgc aggcgaactt
    13081 cctcaaaatc agtcgtgtgc aacttcagta gaatattcat aggctcggat aatctgagcg
    13141 acaactggat ggcgaaccac atccttggct gaaaaatgaa caaagtcaat ctgatggatg
    13201 ttcttgagtt tatcttgagc atcaatcaaa ccggacttga cattacgtgg caggtcaatc
    13261 tgactgatat ctccattgac aatcatctta gaatgaaagc ctaaacgcgt caagaacatc
    13321 ttcatctgca tgatggtcgt gttttgcgcc tcatcgagaa tgacaaaggc atcatccaag
    13381 gtccggccac gcatataggc aaggggcgca atttcgataa tttcacgctc catgagacga
    13441 gtcgtttggt ctttcccaag aatttgatac aaggcatcgt aaacaggacg aaggtaagga
    13501 tccaccttct ccttaagatc acccggaaga aatccaagac tctctcccgc ttccaccgct
    13561 ggacgagtta ggataattcg cttgacttgc ccacgtttaa gggcagtcac tgccaaggtc
    13621 actgcaagga aggtcttccc tgtacctgct ggcccaattc caaaggtcac atcatgctgt
    13681 ttgacactgt ccacataaag tttttgacct aaggttttga cgcggatagg cttcccagta
    13741 ttatccttga tgatttcttc ttcgtaaagg gcgacaaact tgtcaatttc atcatttttg
    13801 accatactaa tagccgtcac tacatctggc gtaccaacgg tcatcccacg atttaccaag
    13861 gccatgagag cttgaataac ctgacgggct tcctcgcaag cagactcttc tcccaaaacc
    13921 tggacaatct ccgtacgagc atgaatcaca acatcaagct cttcttccat caaacgaaga
    13981 tggcgttcat tggaaccaaa aagatgaaac aggtcatctg gatgactcag ttgaatgtct
    14041 attgaatgtt ccttcaaata aagaacctct ctaatccttt tatttctttt tattatagca
    14101 gagggatgga gaaattacta gcccaaaccc aatgaataaa tgctagtgtt ctagatattc
    14161 ctgccaaatg ctgtcaaaat ctcctaggtt aaaagagaaa ctggcatgct cctccaaaaa
    14221 gcgactgacc tcatcaaaat catctgtatg ttttggaaaa gctgcctctt caaaagcgag
    14281 gtctgccaaa attgctttgg gattgttact tttaggattg cgctcggtca tgagccaagt
    14341 gtaaaatgat tttctcataa gcctccctaa atcaactctg taccaaactg gtcctgcttg
    14401 attttaccag ccttcataag accacctaaa gctttcttga actgaccttt agaaatgcca
    14461 aaggttgcct tgatgtcgtc tggagatgac ttgtcattta aggtcatgaa accgccattg
    14521 ctttccaaat aagtcaaaat catctgagca tcgttttcca acatttcaaa ggagcgtggt
    14581 ttgagggaga ggttcaaagt gcggtccact tcacggaaac caataacgcg cgcatctaat
    14641 acttgcccca aacgtggctc tgcgtaacgc tcgctaggat gaataaaacc aagcatatta
    14701 ttttctggta ggtaaacaaa agttcctgat agcttgagac ggtaaacaat ggctggccag
    14761 ttttggttct gcatgttgtt gtaggcagga cgagcaagac gttggaagtc ttcttgataa
    14821 gccaagagac cccagatacg gtctttctta tccacttcaa gacggatgta gagttggtcg
    14881 cccttcttag gccagagttc cttgagctca gggagaatat cgagtgacac aacgatttcc
    14941 ttgtcaggaa ggcctgtatc cacaaagaca cccaagtcct tacgaacctc tgtgacacgt
    15001 ccccaaccaa attggtcctg agtggcagtc acttctaagc ttgtcaggcg gagtttttgc
    15061 ttcatatccg tgtatgcaaa acctttgacc gtatccccta ctgtatgttg gccttcttcc
    15121 ttagcaagag cataggtttg accatccttt tgcacaaagt aaaaacggtc gttttcatcg
    15181 atgatcagtc caacgataaa acttgcaaga tttgtattca tatttccttc tttcgaataa
    15241 aactcagcca gcaatgccaa ctgagttttt ctgtttattt ttagacttcc aaaagttctt
    15301 tctctttgtt ggcagtcata tcgtcgatgt gtttaacagc atcgtctgtt actttttgaa
    15361 tgtctttttc aagagtcttc aattcgtctt cagtgatttc ttttgctttt tcttgtttct
    15421 tagcttcgtc catagcatcg cgacggatat tgcggacagc cactttagca ttttcgccga
    15481 ccttcttcac ttctttagca aggtcacgac gagtctcttc tgtaagagct gggacaacca
    15541 agcgaatcac agaaccgtca ttagctggtg tgataccaag atcagaagcg ttcaaggcac
    15601 gttcgatgtc tttcaatgaa gacttgtcaa atggtgttac caacaaaaca cgcgcttctg
    15661 gaatcgtaat tgaagcgatt tggttaagag gagtttcaac tccatagtat tctacatgta
    15721 tacggtcaag caagcttgca ttggcacgac cagcacggat accaccaaat tcacgagcaa
    15781 gtgattggtg agactgggtc attctctctt tagctttttc aataattgcg ttagccatat
    15841 tctttcttat tccttttctt cgatattatt tgaaactgtt gttccgatat tttcaccaaa
    15901 tacgacacgt ttgatgttgc ctgattggtt catgttgaag acaaccaagt caatgtcgtt
    15961 gtccattgag agggttgaag ctgttgagtc catgatacga agacctttat tgataacgtc
    16021 acggtgggtc aattcttcaa acttaacagc tgtcttatct ttcttaggat cggcattgta
    16081 aacaccatcg acaccatttt tagccatgag gatggcatcc gcttcgattt cagctgcacg
    16141 aagggccgct gttgtatctg tcgagaagta tggtgaacca attccagcac caaagataac
    16201 gatacggcct ttttcaaggt gacgaagggc acgtccacgg acataaggct ctgccacttg
    16261 ttgcatagca atagctgttt gtacacgcgt atcaacccca acttgttgca atgaatctgc
    16321 catcacaaga gcattcataa cagtcccaag cattccagtg taatctgcct gaacacggtc
    16381 catacctgct tctgctgcag gttctccacg ccagagattt cctccaccaa taacaagggc
    16441 aatttcgata cctaagctat gaacttcttg aatctctttt gcgattgttt gaactgtttg
    16501 gatatcaatc cctacgccac gttcaccggc aagggcttca cctgataact tgattaaaat
    16561 acgtttatac ttgggattcg ccattttcac tctccttctt tcatcctacc tattttatca
    16621 caatttctaa gatttttata gtatcatgaa caattctttc aaaaaaatta gacagtcaaa
    16681 aattcctcta agtcggcaag ggcacgctct gcaatttttt cataacgagc cttcttatca
    16741 cggatacgct cgccttccaa ctccttgatg atcccaaaat tgacattcat tggttggaaa
    16801 tgtttgctgt cggcatgggt aatgtaatga gctaagcttc caatcgctgt cgtctcgggg
    16861 aaaataacct cgctttcttc cttgaagaga cgagctgcgt taattcccgc aactaagccc
    16921 gaagccgccg actcaacata gccttccacc cccgtcatct gaccagcaaa gaagagattt
    16981 ggttgtttct tggaacggta agtctgctca agaagatttg gtgaatccat gtaagaattg
    17041 cgatgcatga caccataacg gacaaactcc gcattttcaa gacccggaat catttggaag
    17101 acacgctttt gttctcccca tttgaggtgg gtctggaaac caacaatatt gtataggcta
    17161 ccagctgcat tatcctgacg aagttgcaca accgcataag gtgttttaaa ttctccatca
    17221 cgaggtcctg tgtagtcgtc cggatactca agaccgactg gcttcatagg gccataaagc
    17281 atagttttaa tgccacgttt ggccataact tcgattggca tacatccttc aaagtacttt
    17341 tctttttcaa aagaattgag cggtgcttct tccgcattga ccaaggcttc atggaaatcc
    17401 ataaactctt gcttggtcat tggagcattg agataggctg cttctccctt atcataacga
    17461 gatttgagat agaccttact catatcgata gtgttgacat cgataatagg cgctgctgca
    17521 tcgtagaaat agaagccatc gccattatta agggcatgaa tcttttcagc cagggcatcg
    17581 ctagtcaagg gaccagtcgc cacaactgta ataacatctg ttggcaattc tgtaatttca
    17641 tcacgcacca cttcaatcaa ggggtggttg accacttttt cggtcaccat ttgagagaaa
    17701 ccatcacgat ccaccgcaag ggctccaccg gcaggaacac gtgtagcctc agcagattcc
    17761 aagataacag aacccaagcg acgcatttct tccttgagaa gaccaactgc atttgtcaaa
    17821 gcatccccac gcaaagaatt ggaacaaacc aactcagcaa aattgtctgt tttatgctgg
    17881 ggtgtagact tgacaccacg catttcatat agtttaactg gaataccacg ctctgcgatt
    17941 tggtaagctg cttcagaacc tgccaaacca gcaccgataa cattgatata agattgagac
    18001 acgacactaa tacctctttg ggagtgtgaa gttaagattc acattgaaaa agccaatcag
    18061 acttacaagc tttcgagttt cttggctcag gctgaaaaag tccattggac ttacttcgct
    18121 ctcgaatttc ttggctca
//
LOCUS       DAVBOG010000043        18101 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.043, whole genome shotgun sequence.
ACCESSION   DAVBOG010000043 DAVBOG010000000
VERSION     DAVBOG010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 18101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18101
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.043"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            3..308
                     /locus_tag="VQ865_001632"
     CDS             3..308
                     /locus_tag="VQ865_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3135947.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFRIPAMSAPVFDNIEAAIKEHGLS"
     gene            356..1831
                     /locus_tag="VQ865_001633"
     CDS             356..1831
                     /locus_tag="VQ865_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000338710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HET3135948.1"
                     /translation="MDAIFDLIGKVFNPILEMGGPVIMLIILTVLALLFGVKFSKALE
                     GGIKLAIALTGIGAIIGMLNGAFSASLAKFVENTGIQLSITDVGWAPLATITWGSAWT
                     LYFLLIMLIVNVVMLAMKKTDTLDVDIFDIWHLSITGLLIKWYADNNGVSQGVSLFIA
                     TAAIVLVGVLKIINSDLMKPTFDDLLNAPSSSPMTSTHMNYMMNPVIMVLDKIFEKFF
                     PGLDKYDFDAAKLNKKIGFWGSKFFIGFILGIVIGIMGTPHPIAGVADADKWRLVIKG
                     WLSLGLTAGVSLELFSLIGSWFIAAVEPLSQGITNVATKRLQGRKFNIGLDWPFIAGR
                     AEIWACANVLAPIMLIEAVLLSKVGNGILPLAGIIAMGVTPALLVVTRGKLLRMIIFG
                     TLLLPLFLLSGTLIAPFATELAKGVGAFPEGVSQTQLITHSTLEGPIEKLLGWTIGNT
                     TTGDIKAILGAVAFLVFYIGIFAWYRKQMIKRNEEYAAKAK"
     gene            1854..1931
                     /locus_tag="VQ865_001634"
                     /pseudo
     CDS             1854..1931
                     /locus_tag="VQ865_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            2091..8792
                     /locus_tag="VQ865_001635"
     CDS             2091..8792
                     /locus_tag="VQ865_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HET3135949.1"
                     /translation="MGKGHWNRKRVYSIRKFAVGACSVMIGTCAVLLGGNIAGESVVY
                     ADETLITHTAEKPKEEKMIVEEKADKALETKNVVERTEQSEPSSTEAIASEKKEDEAV
                     TPKEEKVSAKLEEKAPRIESQASSQEKPLKEDAKAVTNEEMNQMIEDRKVDFNQNWYF
                     KLNANSKEAIKPDVDVSTWKKLDLPYDWSIFNDFDHESPAQNEGGQLNGGEAWYRKTF
                     KLDEKDLKKNVRLTFDGVYMDSQVYVNGQLVGHYPNGYNQFSYDITKYLHKDGRENVI
                     AVHAVNKQPSSRWYSGSGIYRDVTLQVTDKVHVEKNGTTILTPKLEEQQHGKVETHVT
                     SKIANTDDKDHELVAEYQIVERGGHAVTGLVRTASRTLKAHESTSLDAILEVERPKLW
                     TVLNDKPALYELITRVYRDGQLVDAKKDLFGYRYYHWTPNEGFSLNGERIKFHGVSLH
                     HDHGALGAEENYKAEYRRLKQMKEMGVNSIRTTHNPASEQTLQIAAELGLLVQEEAFD
                     TWYGGKKPYDYGRFFEKDATHPEARKGEKWSDFDLRTMVERGKNNPAIFMWSIGNEIG
                     EANGDAHSLVTVKRLVKVIKDVDKTRYVTMGADKFRFGNGSGGHEKIADELDAVGFNY
                     SEDNYKALRAKHPKWLIYGSETSSATRTRGSYYRPERELKHSNGPERNYEQSDYGNDR
                     VGWGKTATASWTFDRDNAGYAGQFIWTGTDYIGEPTPWHNQNQTPVKSSYFGIVDTAG
                     IPKHDFYLYQSQWVSVKKKPMVHLLPHWNWENKELASKVADSEGKIPVRAYSNASSVE
                     LFLNGKSLGLKTFNKKQTSDGRTYQEGANANELYLEWKVAYQPGTLEAIARDESGKEI
                     ARDKITTAGKPAAVRLIKEDHAIAADGKDLTYIYYEIVDSQGNVVPTANNLVRFQLHG
                     QGQLVGVDNGEQASRERYKAQADGSWIRKAFNGKGVAIVKSTEQAGKFTLTAHSDLLK
                     SNQVTVFTGKKEGQEKTVLVTEVPKVQTIIGEAPEMPTTVPFVYSDGSRAERPVTWSS
                     VDVSKPGIVTVKGMADGREVEARVEVIALKSELPVVKRIAPNTDLNSVDKSVSYVLTD
                     GSVQEYEVDKWEIAEEDKAKLAIPGSRIQATGYLEGQPIHATLVVEEGNPAAPAVPTV
                     TVGGEAVTGLTSQKPMQYRTLAYGAKLPEVTASAKNAAVTVLQASAANGMRASIFIQP
                     KDGGPLQTYAIQFLEEAPKIAHLSLQVEKADSLKEDQTVKLSVRAHYQDGTQAVLPAD
                     KVTFSTSGEGEVAIRKGMLELHKPGAVTLKAEYEGAKGQVDLTIQANTEKKIAQSIRP
                     VNVVTDLHQEPTLPSTVTVEYDKGFPKAHKVTWQAIPKEKLDSYQTFEVLGKVEGIDL
                     EARARVSVEGIVSVEEVSVTTPIAEAPQLPESVRTYDSNGHVSSAKVAWDAIRIEQYA
                     KEGVFTVNGRLEGTQLTTKLHVRVSAQTEQGANISDQWTGSELPLAFASDSNPSDPVS
                     NVNDKLISYNNQPANRWTNWNRSNPEASVGVLFGDSGILSKRSVDNLSVGFHEDHGVG
                     APKSYVIEYYVGKTVPTAPKNPSFVGNEDHVFNDSANWKPVTNLKAPAQLKAGEMNHF
                     SFDKVETYAVRIRMVKADNKRGTSITEVQIFAKQVAAAKQGQTRIQVDGKDLANFNPD
                     LTDYYLESVDGKVTAVTASVSNNGLATVVPSVREGEPVRVIAKAENGDILGEYRLHFT
                     KDKSLLSHKPVAAVKQARLLQVGQALELPTKVPVYFTGKDGYETKDLTVEWEEVPAEN
                     LTKAGQFTVRGRVLGSNLVAEITVRVTDKLGETLSDNPNYDENSNQAFASATNDIDKN
                     SHDRVDYLNDGDHSENRRWTNWSPTPSSNPEVSAGVIFRENGKIVERTVAQGKVQFFA
                     DSGTDAPSKLVLERYVGPEFEVPTYYSNYQAYDADHPFNNPENWEAVPYRADKDIAAG
                     DEINVTFKDIKAKAMRWRMERKADKSGVAMIEMTFLAPSELPQESTQSKILVDGKELA
                     DFAENRQDYQITYKGQRPKVSVEENNQVASTVVDSGEDSLPVLVRLVSESGKQVKEYR
                     IHLTKEKPVSEKTVAAVQEDLPKLEFVEKDLAYKTVEKKDSTLYLGETRVEQEGKTGK
                     ERIFTAINPDGSKEEKLREVVEAPTDRIVLVGTKPVAQEAKKPQVSEKADTKPIDSSE
                     ASQTNKAQLPNTGSASSQAAVAAGLALLGLSAGLVVTKGKKED"
     gene            complement(9040..9896)
                     /locus_tag="VQ865_001636"
                     /pseudo
     CDS             complement(9040..9896)
                     /locus_tag="VQ865_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270419.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(10107..10466)
                     /locus_tag="VQ865_001637"
     CDS             complement(10107..10466)
                     /locus_tag="VQ865_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HET3135950.1"
                     /translation="MGMILMKLASILLLILTLVICIILTKLFRLKKLGRNFADLAFPV
                     LVFEYYLITAKTFTHNFLPRLGLTLSILAIILVFFFLLKKRSFYYPKFIKFFWRAGFL
                     LTLIMYVEMIVELFLMK"
     gene            10558..11514
                     /locus_tag="VQ865_001638"
                     /pseudo
     CDS             10558..11514
                     /locus_tag="VQ865_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002881980.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein.; internal stop;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
     gene            11498..12055
                     /locus_tag="VQ865_001639"
     CDS             11498..12055
                     /locus_tag="VQ865_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HET3135951.1"
                     /translation="MKRPLEMAHDFLAEVVTKEDVVVDATMGNGHDTLFLAKLAKQVY
                     AFDIQKQALEKTQERLHQADLTNAQLILQGHETLDQFVIKAKAGIFNLGYLPSADKSV
                     ITRPQTTIEALEKLCGLLVKGGRIAIMIYYGHEGGDLERDAVLDFVIQLNQQEYTAAI
                     YRTLNQVNNPPFLVMIEKLERYRHG"
     gene            12048..12302
                     /locus_tag="VQ865_001640"
     CDS             12048..12302
                     /locus_tag="VQ865_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000361102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3135952.1"
                     /translation="MDKQYLHEKLDAMRQNFVESTHHERAVGVLDQAHMSKKMLKIKK
                     KLVALEMERCQRKIEHKDCSKIDQKIKEQKEIFESCCKKD"
     gene            12314..14368
                     /locus_tag="VQ865_001641"
     CDS             12314..14368
                     /locus_tag="VQ865_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HET3135953.1"
                     /translation="MELLIYLILFLLVLIVSSTTNKLLPFLPLPLVQILLGIVIGLFL
                     PNTDFHLNTELFLALVIGPLLFREAEEADVTAILKHWRIIVYLIFPVIFISTLSLGGL
                     AHLLWFSLPLAACLAVGAALGPTDLVAFASLSERFSFPKRVSNILKGEGLLNDASGLV
                     AFQVALTAWTTGAFSLGQASSSLIFSILGGFLIGFLTAMTNRFLHTFLLSVRATDIAS
                     ELLLELSLPLVTFFLAEEVHVSGIIAVVVAGILKASRFKKITLLEAQVDTVTETVWHT
                     VTFMLNGSVFVILGMELEMIAEPILTNPIYNPLLLLLSLIALTFVLFVIRFIMIYGYY
                     AYRTRRLKKKLNKYMKDMFLLTFSGVKGTVSIATILLIPSNLEQEYPLLLFLVAGVTL
                     VSFLTGLLVLPHLSDEEEKSKDYLMHIAILNEVTLELEKELEDTRNKLPLYAAIDNYH
                     GRIENLILSQENQDDQEDWAALKLLILSIESDGLEQAYEEGNISNRAYRVYQRYLKNI
                     EQGINRKLASRLTYYFLVSLRILRFLLHEVFTLGKTFRSWKDKEQSRLRALDYDQIAE
                     LYLANTEMIIESLENLKGVYRRSLISFMQESRLRETAIISSGAFVERVINRVKPNNID
                     EMLRGYYLERKLIFEYEEKRLITTKYAKKLRQNVNNLENYSLKEAANTLPYDMVELVR
                     RN"
     gene            14547..15407
                     /locus_tag="VQ865_001642"
     CDS             14547..15407
                     /locus_tag="VQ865_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HET3135954.1"
                     /translation="MKKWWKELIDKPLLKAFLHYYQASDSELTSVAVAYYWLISIFPL
                     LLVVVNILPYFQIPVGEFLCFMKDVLPPSLYEGVEKIAREVLTQPSTGLLSFSVLSAL
                     WSFSKSMNFLQKAFNKAYGVEKSRGLISHQMLSLLVSFGLQLLFAFALFLILFGQMIL
                     ALLAHYWTKDGIIYQALQGLAGPLIYALLFAILVMLYYFLPNISNRKISYTLPGSAFV
                     LLVILGLLTLFSSYLNYYVHHLVDVRILGSVLLVVMMFWFILIAKIVILGAVINASMQ
                     SLKDPVFKKD"
     gene            15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ865_001643"
     CDS             15626..16336
                     /gene="ccdA2"
                     /locus_tag="VQ865_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000509848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3135955.1"
                     /translation="MGHIFFFLSVFLAGILSFFSPCILPLLPVYTGVLLDDKDGAQAS
                     SGKFSISVTSLLRTLAFIAGISFIFILLGYGAGFLGDLLYASWFQYLTGAIIILLGLH
                     QMEILHFKGLYKEKRLQLQGQGQNGKGYSQAFLLGLTFSFAWTPCVGPVLGSVLALAA
                     SGGSGAWQGAGLMLVYTLGLALPFLLLALTSSYVLKHFRKLHPYLGILKKVGGFLIIV
                     MGLLVLFGNASILSQLFE"
     gene            16356..16922
                     /locus_tag="VQ865_001644"
     CDS             16356..16922
                     /locus_tag="VQ865_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redoxin family protein"
                     /protein_id="HET3135956.1"
                     /translation="MKKWQTCVLGAGSLLWLTACSGKSVTSEHQTKDEMKTEQTASKT
                     SAAKGKEVADFELMGVDGKTYRLSDYKGKKVYLKFWASWCSICLASLPDTDEIAKEAG
                     DDYVVLTVVSPGHKGEQSEADFKNWYKGLDYKNLPVLVDPSGKLLETYGVRSYPTQAF
                     IDKEGKLVKTHPGFMEKDAILQTLKELA"
     gene            16933..18045
                     /gene="msrB"
                     /locus_tag="VQ865_001645"
     CDS             16933..18045
                     /gene="msrB"
                     /locus_tag="VQ865_001645"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3135957.1"
                     /translation="MNDKLKIFLLLGVFFLAITGFYVLLIRNAGQTDASQIEKAAVSQ
                     GGKAVKKTEISKDADLHEIYLAGGCFWGVEEYFSRVPGVTDAVSGYANGRGETTKYEL
                     INQTGHAETVHVTYDAKQISLKEILLHYFRIINPTSKNKQGNDVGTQYRTGVYYTDDK
                     DLEVINQVFDEVAKKYDQPLAVEKENLKNFVVAEDYHQDYLKKNPNGYCHINVNQAAY
                     PVIDASKYPKPSDEELKKTLSPEEYAVTQENQTERAFSNRYWDKFESGIYVDIATGEP
                     LFSSKDKFESGCGWPSFTQPISPDVVTYKEDKSYNMTRMEVRSRVGDSHLGHVFTDGP
                     QDKGGLRYCINSLSIRFIPKDQMEEKGYAYLLDYVD"
BASE COUNT         5445 a         3450 c         3979 g         5227 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagtcatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattccgta
      241 tcccagcaat gagcgctcca gtatttgaca atattgaagc agctattaaa gaacacggat
      301 taagctaatt ctaatttgtt aacattcata taacataaaa aagggaggaa ctgttatgga
      361 tgcaatcttt gacctaatcg gaaaggtttt caatcccatc ttagaaatgg gtggacctgt
      421 catcatgttg atcattttga cagtattggc tttacttttt ggagtgaaat tctccaaagc
      481 gcttgaaggt ggtatcaaac ttgccatcgc tcttacaggt atcggtgcta tcatcggtat
      541 gctaaatggt gctttctcag catcacttgc aaaattcgtt gaaaacactg gtatccaatt
      601 gagtattaca gacgttggtt gggcaccact cgcaacaatc acttggggtt ctgcttggac
      661 actatacttc ttgctcatca tgttgattgt caacgtagtg atgcttgcta tgaagaaaac
      721 cgatacactt gatgtcgata tatttgatat ctggcacttg tctatcacag gtctcttgat
      781 taaatggtat gctgataaca atggtgtgag tcaaggggtt tcactcttta ttgctacagc
      841 agctatcgtc cttgtcggtg tgttgaaaat tatcaactct gacttgatga aacctacatt
      901 tgatgacctt cttaacgccc caagttcatc accaatgaca tcaactcaca tgaactacat
      961 gatgaaccca gttatcatgg ttttggataa gatttttgaa aaattcttcc caggccttga
     1021 taaatatgac tttgatgctg ctaaattgaa caagaaaatc ggtttctggg gatctaaatt
     1081 cttcatcggt ttcatccttg gtatcgttat cggtattatg ggaactccac atccaattgc
     1141 aggtgttgca gatgcagata aatggcgtct tgttatcaaa ggatggttgt ctcttggttt
     1201 gactgccggt gtatctttgg aactcttctc acttatcggt tcatggttca tcgcagccgt
     1261 agaaccacta tcacaaggta ttacaaacgt tgctactaaa cgtcttcaag gacgtaaatt
     1321 caatatcggt cttgactggc cattcatcgc tggtcgtgct gaaatctggg cttgtgccaa
     1381 cgtacttgca ccaatcatgt tgattgaagc agtgcttctt tcaaaagttg gaaatggtat
     1441 cttgccactt gcaggtatca tcgctatggg tgttactcca gctctcttgg ttgtaactcg
     1501 tggtaaattg ctccgtatga ttatcttcgg aacactcttg ttgccactct tccttctttc
     1561 aggtaccctt attgcaccat ttgcaacaga acttgctaaa ggtgtaggtg ccttcccaga
     1621 aggtgtgagc caaactcaat tgattactca ctctactctt gaaggaccaa tcgaaaaact
     1681 tcttggttgg acaattggta acactacaac tggtgatatc aaagcaatcc ttggtgcagt
     1741 agccttcctt gtattctata tcggtatctt tgcttggtac agaaaacaaa tgatcaaacg
     1801 taacgaagag tacgcagcaa aagcaaaata atgcgctcct ataaaatata aactcaatga
     1861 aaatcaaaga gcaaactagg aaactagcca caggttgctc aaaacacagt tttgaggttg
     1921 tagatgaaac tgacgaagtc agtaatcata tctacggcaa ggcgacgctg acgaagtttg
     1981 aattggattt tcgcagagtg taaattgttg aaactaggtt gtcataccat gtataccact
     2041 tgggctttgg tagtagctaa ctgcactaaa tataatataa ggagggtttt atggggaaag
     2101 gccattggaa tcggaaaaga gtttatagca ttcgtaagtt tgctgtggga gcttgctcag
     2161 taatgattgg gacttgtgca gttctattag gaggaaatat agctggagaa tctgtagttt
     2221 atgcggatga aacacttatt actcatactg ctgagaaacc taaagaggaa aaaatgatag
     2281 tagaagaaaa ggctgataaa gctttggaaa ctaaaaatgt agttgaaagg acagaacaaa
     2341 gtgaacctag ttcaactgag gctattgcat ctgagaagaa agaagatgaa gccgtaactc
     2401 caaaagagga aaaagtgtct gctaaactgg aagaaaaagc tccaaggata gaatcacaag
     2461 cttcaagtca agaaaaaccg ctcaaggaag atgctaaagc tgtaacaaat gaagaaatga
     2521 atcaaatgat tgaagacagg aaagtggatt ttaatcaaaa ttggtacttt aaactcaatg
     2581 caaattctaa ggaagccatt aaacctgatg tagacgtatc tacgtggaaa aaattagatt
     2641 taccgtatga ctggagtatc tttaacgatt tcgatcatga atctcctgca caaaatgaag
     2701 gtggacagct caacggtggg gaagcttggt atcgcaagac tttcaaacta gatgaaaaag
     2761 acctcaagaa aaatgttcgc cttacttttg atggcgtcta catggattct caagtttatg
     2821 tcaatggtca gttagtgggg cattatccaa atggttataa ccagttctca tatgatatca
     2881 ccaaatacct tcacaaagat ggtcgtgaga atgtgattgc tgtccatgca gtcaacaaac
     2941 agccaagtag ccgttggtat tcaggaagtg gtatctatcg tgatgtgact ttacaagtga
     3001 cagataaggt gcatgttgag aaaaatggga caactatttt aacaccaaaa cttgaagaac
     3061 aacaacatgg caaggttgaa actcatgtga ccagcaaaat cgccaatacg gacgacaaag
     3121 accatgaact tgtagccgaa tatcaaatcg ttgaacgagg tggtcatgct gtaacaggct
     3181 tagttcgtac agcgagtcgt accttaaaag cacatgaatc aacaagccta gatgcgattt
     3241 tagaagttga aagaccaaaa ctctggaccg ttttaaatga caaacctgcc ttgtacgaat
     3301 tgattacgcg tgtttaccgt gacggtcaat tggttgatgc taagaaggat ttgtttggtt
     3361 accgttacta tcactggact ccaaatgaag gtttctcttt gaatggtgaa cgtattaaat
     3421 tccatggagt atccttgcac cacgaccatg gggcgcttgg agcagaagaa aactataaag
     3481 cagaatatcg ccgtctcaaa caaatgaagg agatgggagt taactccatc cgtacaaccc
     3541 acaaccctgc tagtgagcaa accttgcaaa tcgcagcaga actaggttta ctcgttcagg
     3601 aagaggcttt tgatacttgg tatggtggca agaaacctta tgactatgga cgtttctttg
     3661 aaaaagatgc cactcaccca gaagctcgaa aaggtgaaaa atggtctgat tttgacctac
     3721 gtaccatggt cgaaagaggc aaaaacaacc ctgctatctt catgtggtca attggtaatg
     3781 aaataggtga agctaatggt gatgcccact ctttagtaac tgttaaacgt ttggtcaagg
     3841 ttatcaagga tgttgataag actcgctatg ttaccatggg agcagataaa ttccgtttcg
     3901 gtaatggtag cggagggcat gagaaaattg ctgatgaact cgatgctgtt ggatttaact
     3961 attctgaaga taattacaaa gcccttagag ctaagcatcc aaaatggttg atttatggat
     4021 cagaaacatc ttcagctacc cgtacacgtg gaagttacta tcgccctgaa cgtgaattga
     4081 aacatagcaa tggacctgag cgtaattatg aacagtctga ctatgggaat gatcgtgtgg
     4141 gttgggggaa aacagcaacc gcttcatgga cttttgaccg tgacaacgct ggctatgctg
     4201 gacagtttat ctggacaggt acggactata ttggtgaacc tacaccatgg cacaaccaaa
     4261 atcaaactcc tgttaagagc tcttactttg gtatcgtaga tacagccggc attccaaaac
     4321 atgacttcta tctctaccaa agccaatggg tttctgttaa gaagaaaccg atggtacacc
     4381 ttcttcctca ctggaactgg gaaaacaaag aattagcatc caaagtagct gactcagaag
     4441 gtaagattcc agttcgtgct tattcgaatg cttctagtgt agaattgttc ttgaatggaa
     4501 aatctcttgg tcttaagact ttcaataaaa aacaaaccag cgatgggcgg acttaccaag
     4561 aaggtgcaaa tgctaatgaa ctttatcttg aatggaaagt tgcctatcaa ccaggtacct
     4621 tggaagcaat tgctcgtgat gaatctggca aggaaattgc tcgagataag attacgactg
     4681 ctggtaagcc agcggcagtt cgtcttatta aggaagacca tgcgattgca gcagatggaa
     4741 aagacttgac ttacatctac tatgaaattg ttgacagcca ggggaatgtg gttccaactg
     4801 ctaataatct ggttcgcttc caattgcatg gtcaaggtca actggtcggt gtagataacg
     4861 gagaacaagc cagccgtgaa cgctataagg cgcaagcaga tggttcttgg attcgtaaag
     4921 catttaatgg taaaggtgtt gccattgtca aatcaactga acaagcaggg aaattcaccc
     4981 ttactgccca ctctgatctc ttgaaatcga accaagtcac tgtctttact ggtaagaaag
     5041 aaggacaaga gaagactgtt ttggtgacag aagtgccaaa agtacagacc attattggag
     5101 aggcacctga aatgcctacc actgttccgt ttgtatacag tgatggtagc cgtgcagaac
     5161 gtcctgtaac ctggtcttca gtagatgtga gcaagcctgg tattgtaacg gtgaaaggta
     5221 tggctgacgg acgagaagta gaagctcgtg tagaagtgat tgctcttaaa tcagagctac
     5281 cagttgtgaa acgtattgct ccaaatactg acttgaattc tgtagacaaa tctgtttcct
     5341 atgttttgac tgatggaagt gtacaagagt atgaagtgga caagtgggag attgccgaag
     5401 aagataaagc taagttagca attccaggtt ctcgtattca agcgaccggt tatttagaag
     5461 gtcaaccaat tcatgcaacc cttgtggtag aagaaggcaa tcctgcggca cctgcagtac
     5521 caactgtaac ggttggtggt gaagctgtca caggtcttac tagtcaaaaa ccaatgcaat
     5581 accgcactct tgcttatgga gctaagttgc cagaagtcac agcaagtgct aaaaatgcag
     5641 ctgttacagt tcttcaagca agcgcagcaa acggcatgcg tgcgagcatc tttattcagc
     5701 ctaaagatgg tggccctctt caaacctatg caattcaatt ccttgaagaa gcgccaaaaa
     5761 ttgctcactt gagcttgcaa gtggaaaaag ctgacagtct caaagaagac caaactgtca
     5821 aattgtcggt tcgagctcac tatcaagatg gaacgcaagc tgtattacca gctgataaag
     5881 taaccttctc tacaagtggt gaaggggaag tcgcaattcg taaaggaatg cttgagttac
     5941 ataagccagg agcagtcact ctcaaagcgg aatatgaggg agctaaaggc caagttgatc
     6001 tcactatcca ggccaatact gagaagaaga ttgcgcaatc tatccgtcca gtaaatgtag
     6061 tgacagattt acaccaagaa cctactcttc cgtcaacagt aacggttgag tatgacaaag
     6121 gtttccctaa agctcacaaa gtcacttggc aagctattcc gaaagaaaaa ctagactcct
     6181 atcaaacctt tgaagtacta ggtaaagttg aaggaattga ccttgaagcg cgtgcaagag
     6241 tctctgtaga aggtatcgtt tcagttgaag aagtcagtgt gacaactcca atcgcagaag
     6301 caccacaatt accagaaagc gttcggacat atgattcaaa tggtcacgtt tcatcagcta
     6361 aggttgcatg ggatgcgatt cgtatagagc aatacgctaa ggaaggtgtc tttacagtta
     6421 atggtcgctt agaaggtact caattaacaa ctaaacttca tgttcgcgta tctgctcaaa
     6481 ctgagcaagg tgcaaatatt tctgaccaat ggaccggttc agaattgcca cttgcctttg
     6541 cttcagactc aaatccaagc gacccagttt caaatgttaa tgacaagctc atttcctaca
     6601 ataaccaacc agccaatcgt tggacaaact ggaatcgtag taatccagaa gcttcagtcg
     6661 gtgttctgtt tggagattca ggtatcttga gcaaacgctc cgttgataat ctaagtgtcg
     6721 gattccacga agaccatgga gttggtgcac cgaagtctta tgtgattgag tattatgttg
     6781 gtaagactgt cccaacagct cctaaaaacc ctagttttgt tggtaatgag gaccatgtct
     6841 ttaatgattc tgccaactgg aaaccagtta ctaatctaaa agcccctgct caactcaagg
     6901 ctggagaaat gaaccacttt agctttgata aagttgaaac ctatgctgtt cgtattcgca
     6961 tggttaaagc agataacaag cgtggaacgt ctatcacaga ggtacaaatc tttgcgaaac
     7021 aagttgcggc agccaaacaa ggacaaacaa gaatccaagt tgacggcaaa gacttagcaa
     7081 acttcaaccc tgatttgaca gactactacc ttgagtctgt agatggaaaa gttacggcgg
     7141 tcacagcaag tgttagcaac aatggtctcg ctaccgtcgt tccaagcgtt cgtgaaggtg
     7201 agccagttcg tgtcatcgcg aaagctgaaa atggcgacat cttaggagaa taccgtctgc
     7261 acttcactaa ggataagagc ttactttctc ataaaccagt tgctgcggtt aaacaagctc
     7321 gcttgctaca agtaggtcaa gcacttgaat tgccgactaa ggttccagtt tacttcacag
     7381 gtaaagacgg ctacgaaaca aaagacctga cagttgaatg ggaagaagtt ccagcggaaa
     7441 atctgacaaa agcaggtcaa tttactgttc gaggccgtgt ccttggtagt aaccttgttg
     7501 ctgagatcac tgtacgagtg acagacaaac ttggtgagac tctttcagat aaccctaact
     7561 atgatgaaaa cagtaaccag gcctttgctt cagcaaccaa tgatattgac aaaaactctc
     7621 atgaccgcgt tgactatctc aatgacggag atcattcaga aaatcgtcgt tggacaaact
     7681 ggtcaccaac accatcttct aatccagaag tatcagcggg tgtgattttc cgtgaaaatg
     7741 gtaagattgt agaacggact gttgcacaag gaaaagttca gttctttgca gatagtggta
     7801 cggatgcacc atctaaactc gttttagaac gctatgtcgg tccagagttt gaagtgccaa
     7861 cctactattc aaactaccaa gcctacgacg cagaccatcc attcaacaat ccagaaaatt
     7921 gggaagctgt tccttatcgt gcggataaag acattgcagc tggtgatgaa atcaacgtaa
     7981 catttaaaga tatcaaagcc aaagctatga gatggcgtat ggagcgtaaa gcagataaga
     8041 gcggtgttgc gatgattgag atgaccttcc ttgcaccaag tgaattgcct caagaaagca
     8101 ctcaatcaaa gattcttgta gatggaaaag aacttgctga tttcgctgaa aatcgtcaag
     8161 actatcaaat tacctataaa ggtcaacggc caaaagtctc agttgaagaa aacaatcaag
     8221 tagcttcaac tgtggtagat agtggagaag atagccttcc agtacttgtt cgcctcgttt
     8281 cagaaagtgg aaaacaagtc aaggaatacc gtatccactt gactaaggaa aaaccagttt
     8341 ctgagaagac agttgctgct gtacaagaag atcttccaaa actcgaattt gttgaaaaag
     8401 atttggccta caagacagtt gagaaaaaag attcaacact gtatctaggt gaaactcgtg
     8461 tagaacaaga aggaaaaact ggtaaagaac gtatctttac agcgattaat cctgatggaa
     8521 gtaaggaaga aaaactccgt gaagtggtag aagctccgac agaccgcatc gtcttggttg
     8581 gaaccaaacc agtagctcaa gaagctaaaa aaccacaagt gtcagaaaaa gcagatacaa
     8641 aaccaattga ttcaagtgaa gctagtcaaa ctaataaagc ccagttacca aatacaggta
     8701 gtgcgtcaag ccaagcagca gtagcagcag gtttagctct tctaggtttg agtgcaggat
     8761 tagtagttac taaaggtaaa aaagaagact agaaattttg ataccttctt tatcattaaa
     8821 gaccaaagaa aaactcttgt cctaaataga agataaagag tctggaacaa aatagttctc
     8881 aaccacaaaa aagctagata tttccaattg cggaactcta gctttttaat tttgagtcgt
     8941 tctctgattg tatagtagat tgaaactaga gtagtacact tctacttcta aaacattgtt
     9001 agaaatcgat ttgactgtcc ttatcgattt gtcctgttct tatttgattt cactatgttt
     9061 taggaggtta ttggccataa gtaccaatcc catgtcaatt ctcacttgac gcttgcctct
     9121 cagattacat ctcttgtaac ccaaacaagc ctttatctgc ccaaagacag gttccacatc
     9181 aatcttgcgt tgagcgaaaa tctgtctatc ttggggagat aaaagcgcct gacattcttt
     9241 agctttcaag ttttgatagc gttcgttcat atacagtccc ttttgagggg ctgattcagg
     9301 ttcatcagcg tagtaaacct tgatttcctg ttgaaagtct gtctgtgttt tctggtactt
     9361 gatatggtga aaacgatagc accagccatc aggatgtatg tagctatcct ccttgtcatt
     9421 atagtgccaa ttcgctaagt ttttagctga ctgtttatac cctctctttt gtttcttatc
     9481 aaacatggca tatttaatca gaaggggagt gatttcttct tgaaaataga cttgtatctg
     9541 ttcttgaagt ttggcggaga atttctctgt cgttttcttc cacacaaaac tatacttgtt
     9601 ggcattggct tcaatcttag ttccgtcaat aaacaaacaa tctaaggtca ctaactcttc
     9661 catttttcaa tttttcgacc agagaaaatc ccttgtgaat aggcaaatag aagagtagat
     9721 acaagcattt taaggtgata agacgggcga tcaaaggcat gatagaaggc gtggaaatga
     9781 caatcctcca aggtattcac cactttttca atagtaaaaa cgagatggtc ttgtggcaag
     9841 aaggaactga tttctagtgg taaagttgtt tgatttgtgt tatagtgaat atgcatggga
     9901 tagcctttct aaatggttta ttgtgcaatt ctattttacc aagactatcg caaccatgca
     9961 aaaaagcaac ggcaaatccg ttgctttttt tggagataag agactattgt cccagactct
    10021 tttctttgta taaaattgta tagtgttatt gtctatacta ttttgtagag aaagcaaaaa
    10081 tccctagaaa atgcttaggg attcgactat ttcattaaga acaattcaac aatcatttct
    10141 acatacatga taagggttaa taagaatcct gcacgccaga agaatttgat gaatttagga
    10201 tagtaaaagc tgcgtttttt caaaaggaag aaaaagacga gaataatggc taggatcgag
    10261 agggttagcc ccagtctagg gaggaaatta tgggtaaagg ttttagctgt aatcaagtaa
    10321 tactcaaata ccaagactgg aaaagccaaa tccgcaaagt ttcgtcctag tttttttaat
    10381 ctaaaaagtt tggttaggat aatgcagatg actaaggtca gtatcaataa taaaatagat
    10441 gctaatttca ttaaaatcat acccatattg tatcataaaa aaaggctaat ggaaacgaga
    10501 aacagaggaa tttataagaa agtcaggctt ttgagattgt gggtgatttt tgttataatg
    10561 aaagttataa aatcttataa taccttgaat gattattatc gaaaactctt tggagaaaag
    10621 acttttaaag tccctattga tgcgggattt gactgtccca atcgtgatgg aactgtggct
    10681 catggaggct gtactttttg tacggtttca ggttctggag atgctattgt agccccagat
    10741 gcgcctatcc gtgagcaatt ttataaggaa attgacttta tgcaccgtaa gtggccggat
    10801 gttcagaagt atctggttta ttttcaaaat tttaccaaca ctcatgaaaa ggtggaagtt
    10861 attcgagagc gttatgaaca ggctatcaat gagccaggtg tggtaggaat caatattgga
    10921 acgcgcccag actgtttacc agacgaaacc atcgaatatt tggctgagtt atcggagtgc
    10981 atgcatgtga cgtttgaatt gggcttgcaa actacttatg aagcaacctc tgacctgatt
    11041 aaccgtgcgc attcttatga attgtaggtg gaaacggtca agcgtttgag aaagtatcca
    11101 aaaattgaga ttgtttccca tttgatcaat ggtttgcctg gtgaaaccca tgagatgatg
    11161 gttgaaaatg tccgccgttg tgtcacggat aacgatattc aagggattaa actgcatttg
    11221 ctccatctta tgacaaatac tcgtatgcaa cgagattacc atgaggggcg tttacaattg
    11281 atgagtcagg acgaatatgt cagggtcatc tgtgaccaac tggaaattat tcccaaacat
    11341 atcgtcatcc atcgaattac aggagatgcg cctagggata tgctgcttgg gcctatgtgg
    11401 agcctcaata aatgggaagc tctcaacagc attgagatgg agatgcgacg tcgtggaagt
    11461 gttcaaggat gcaaggctgt aaaacaggag tttgaaaatg aaaagaccac ttgagatggc
    11521 acatgatttt ttggctgagg tcgtgacaaa agaggatgtc gtagtggatg cgactatggg
    11581 aaatggtcat gacacgcttt ttttagccaa gctagccaag caagtctatg cctttgatat
    11641 tcagaagcaa gccttggaaa agacccaaga gcgtttgcat caggctgact tgacaaatgc
    11701 ccagttaatc ttgcaaggcc atgagacact ggaccagttt gtgataaaag ctaaggcagg
    11761 gatttttaat ctgggctatt tgccgtcagc tgataagtct gtcatcaccc gaccgcagac
    11821 aacgattgag gcattagaaa agctatgtgg cttacttgtc aaaggtggac gaattgctat
    11881 tatgatttac tatggtcatg aaggaggcga tctcgagaga gatgctgtct tggattttgt
    11941 gatccagttg aaccaacaag agtacacagc tgccatttac cgaactttaa accaagtcaa
    12001 caacccgccg tttttagtga tgattgaaaa attagagaga tacagacatg gataaacaat
    12061 acttacacga aaagctggat gccatgcgcc agaattttgt tgaatcaacc caccacgaac
    12121 gagcggtggg cgtgctagac caagcgcata tgagcaaaaa aatgcttaaa atcaagaaaa
    12181 aattagttgc tcttgaaatg gaacggtgcc agagaaaaat tgagcacaaa gactgttcca
    12241 agattgacca aaaaatcaaa gagcagaagg agatatttga atcctgttgt aaaaaagatt
    12301 aaggaggacg tgcgtggaat tactgattta cctcatccta tttttactgg ttttgattgt
    12361 ctcaagtaca accaataagc tcctgccctt tttgcctctc cctttggtgc aaattctttt
    12421 gggaattgtg attggtctct ttttacccaa tactgacttt caccttaata cggagttgtt
    12481 tttggcactg gttatcggac ccttgctttt ccgagaggct gaagaagcag atgttacggc
    12541 tattttaaaa cactggcgaa tcattgttta tctcatattt ccagtgattt ttatctcgac
    12601 cctgagtttg ggtggcttgg cccatcttct ttggttcagc cttcccttgg cagcttgctt
    12661 ggctgttggg gcagcccttg gtcctacgga cttggtggcc tttgcctctc tttcggagcg
    12721 ttttagcttt cctaagcgcg tgtccaatat tcttaagggc gaaggactct tgaatgatgc
    12781 ttctggtttg gtggcttttc aggtagcttt gacagcttgg acaactggag ctttttctct
    12841 ggggcaagct agcagttcgc tcatcttttc aatcctaggc ggttttttaa ttggattttt
    12901 aacagccatg accaaccgct tcctccatac cttcttgcta agtgtgcgcg caacggatat
    12961 tgccagtgaa cttttattag aattgagttt gcctctagtg accttctttc tggcagaaga
    13021 agtccatgtt tcaggtatta ttgccgtcgt agttgctgga attttaaagg caagtcgctt
    13081 caagaaaatc acgctcctcg aagcccaagt ggatacggtg accgagacgg tctggcatac
    13141 agtgaccttt atgctcaacg gttctgtctt tgtgatttta gggatggagt tggaaatgat
    13201 agcagaacct atcttgacca atccaatcta taatcctcta cttttattgc tatctctcat
    13261 cgcccttacc tttgtcctct ttgtcattcg ttttattatg atctatggct attatgccta
    13321 tagaacccga cgcctcaaga aaaagctaaa taagtatatg aaggacatgt ttctcttgac
    13381 cttttcaggt gttaagggaa cggtgtcgat tgctacgatt ctcttgatac caagtaatct
    13441 agaacaggag tatcctcttt tgcttttcct tgttgcaggt gtgacgcttg tcagcttttt
    13501 aacaggtctc ttggtcttgc ctcatctttc tgatgaagag gaaaaaagca aggattatct
    13561 catgcatatc gccattttga atgaagtaac gctagagttg gaaaaagagt tggaagacac
    13621 cagaaataaa cttcccctct atgcggctat tgacaattat catggacgta ttgaaaatct
    13681 cattttaagc caagaaaacc aggatgatca agaagactgg gctgctttga aactcttgat
    13741 tcttagtatt gaaagtgatg gtttggaaca ggcctatgaa gaggggaaca ttagcaatcg
    13801 tgcttaccga gtttaccaac gttatctgaa aaatatagaa caaggaatca atcgtaaact
    13861 tgcctcaaga ctgacctatt atttccttgt ttccttgagg attttacgtt ttctccttca
    13921 tgaagttttt actcttggaa agaccttccg tagctggaag gacaaggagc aaagccgtct
    13981 ccgtgctctt gattatgacc aaattgcaga gctctatctt gccaatacgg agatgattat
    14041 tgaaagtttg gaaaacctga agggagtcta cagacgctct ttgattagtt ttatgcagga
    14101 gtctcgtctt cgagaaacag ctattatcag cagtggtgcc tttgtcgaac gggttatcaa
    14161 tcgtgtcaaa cccaacaata tcgatgaaat gctgagaggc tattatctgg agcgcaagtt
    14221 gattttcgaa tacgaagaaa aacgattaat tacaactaag tatgccaaga aattacgaca
    14281 aaatgtaaat aacttagaga actattcctt gaaggaagct gccaataccc tgccgtatga
    14341 tatggtggaa ttggtaagaa gaaattagtt aatactcttc gaaaatctct tcaaaccacg
    14401 tcagcgtcgc cttggattat atatgtgact gacttcgtca gtttcatcta caacctcaaa
    14461 gcagggcttt gagcaacctg cggctagctt cctagtttgc tctttgattt tcattgagta
    14521 taagattata aatgaaggag tatgacatga aaaagtggtg gaaagagctg atagacaagc
    14581 ctttattaaa agcttttttg cattattatc aagcatcaga tagtgagttg accagtgtcg
    14641 cagtagccta ctattggttg atttcgattt tccccctgct tttggtggtg gtcaatatcc
    14701 tcccctattt tcagattcct gtgggagaat ttctgtgctt tatgaaagac gttctgcccc
    14761 caagcctcta tgaaggtgtg gaaaaaatag ccagagaagt tttgacgcaa ccttcaacag
    14821 gtttattaag tttttctgtt ttatcggcgt tatggagttt ttcaaaatct atgaatttct
    14881 tgcaaaaagc ttttaacaag gcttatggcg tcgaaaagag tcgtggactt atttcccatc
    14941 agatgctaag tctcctagtc agttttggct tgcagctcct ctttgcgttt gccttgtttt
    15001 tgatcttatt tggtcagatg attttggctt tacttgctca ttattggaca aaagatggca
    15061 ttatctatca ggctttacaa gggttggcag gtcctctgat ttacgccctc ctctttgcta
    15121 tcttggtcat gctttattat tttcttccca atatatctaa caggaaaatt agctataccc
    15181 taccaggcag tgcctttgtt ctcttagtga ttttaggttt actaactctg ttctctagtt
    15241 atctcaatta ctatgtccat catttggtgg atgtccgaat tttaggttcc gttcttcttg
    15301 ttgttatgat gttttggttt atcttgattg ctaaaattgt tatcctaggc gcggttatca
    15361 atgccagtat gcagagtttg aaagatccgg tctttaaaaa agactaacta tttatccatt
    15421 ataaaagcgc atagtatcaa gactttatag aaccttgata ctatgcgctt ttgcgctttt
    15481 gtgctttgac agttttttgt atagtttttg tccaagattt ctaaatcatc tgattaaatt
    15541 cctattttcc cctatcattg tccctgtttt ttcgaaaatg gaaggagtat aataaatcta
    15601 tcaataaaat gataggagga actttatggg tcatattttc ttttttctaa gtgtcttttt
    15661 ggcagggatt ctatccttct tttctccttg tatcttacct ttgttaccgg tctatacagg
    15721 agtgttacta gatgataagg atggtgctca ggcttctagc ggcaaatttt caatctcagt
    15781 tactagttta ttacgaactc tggcctttat agcaggaatt tcctttatat ttattttgtt
    15841 gggctatgga gctggttttt taggcgattt gctttatgct tcttggttcc aatatcttac
    15901 tggggcaatt attatccttc ttggtttgca ccaaatggag attctacact ttaaggggct
    15961 ttataaggaa aagaggctac aactgcaagg acaggggcaa aatggtaagg gctatagtca
    16021 ggcattttta ttgggcttga cctttagttt tgcttggacg ccttgcgtgg ggccggttct
    16081 ggggtctgtt ttggccttgg cggcttcagg tggttcagga gcttggcagg gagctggtct
    16141 catgttggtg tatacgctgg gcttggcgct accattcttg cttctagctc tgacctctag
    16201 ttatgttttg aaacatttcc gaaaacttca tccctatctc ggaatcctca aaaaagtggg
    16261 tggttttctc attattgtga tgggactctt ggttctgttt ggaaatgctt caattttaag
    16321 tcaattattt gaataaaatg gaaaggaata tcaatatgaa aaaatggcaa acatgtgttc
    16381 ttggagcagg ttcgctcctt tggttgacgg cttgttcagg caagtccgtg actagtgaac
    16441 accaaacgaa agatgaaatg aagacggagc agacagctag taaaacaagc gcagctaaag
    16501 ggaaagaggt ggctgatttt gaattgatgg gagtagatgg caagacctac cgtttatctg
    16561 attacaaggg caagaaagtc tatctcaaat tctgggcttc ttggtgttcc atctgtctgg
    16621 ctagtcttcc agatacggat gagattgcta aagaagctgg tgatgactat gtggtcttga
    16681 cagtagtgtc accaggacat aagggagagc aatctgaagc ggactttaag aattggtata
    16741 agggattgga ttataaaaat ctcccagtcc tagttgaccc atcaggcaaa cttttggaaa
    16801 cttatggtgt ccgttcttac ccaacccaag cctttataga caaagaaggc aagctggtca
    16861 aaacacatcc aggcttcatg gaaaaagatg caattttgca aactttgaag gaattagcct
    16921 aggaggtgtc ttatgaatga taagttaaaa atcttcttgt tgctaggagt attttttcta
    16981 gccataaccg gtttctatgt tctattgata cgaaatgcag ggcagacaga tgcctcgcaa
    17041 attgaaaagg cggcagttag ccaaggagga aaagcagtga aaaaaacaga aattagtaaa
    17101 gacgcagact tgcacgaaat ttatctagct ggaggttgtt tctggggagt ggaggaatat
    17161 ttctcacgcg ttcccggggt gacggatgcc gtttcaggct atgcaaatgg tagaggagaa
    17221 acaaccaagt acgaattgat taaccaaaca ggtcatgcag aaaccgtcca tgtcacctat
    17281 gatgccaagc aaatttctct caaggaaatc ctgcttcact atttccgcat tatcaatcca
    17341 accagcaaaa ataaacaagg aaatgatgtg gggacccagt accgtactgg tgtttattac
    17401 acagatgaca aggatttgga agtgattaac caagtctttg atgaggtggc taagaaatac
    17461 gatcaacctc tagcagttga aaaggaaaac ttgaagaatt ttgtggtggc tgaggattac
    17521 catcaagact atctcaagaa aaatccaaat ggctactgcc atatcaatgt taatcaggcg
    17581 gcctatcctg tcattgatgc cagcaaatat ccaaaaccaa gtgatgagga attgaaaaag
    17641 accctgtcac ctgaggagta tgcagttacc caggaaaatc aaacagaacg agctttctca
    17701 aaccgttact gggataaatt tgaatccggt atctatgtgg atatagcaac tggggaacct
    17761 ctcttttcat caaaagacaa atttgagtct ggttgtggct ggcctagttt tacccaaccc
    17821 atcagtccag atgttgtcac ctacaaggaa gataagtcct acaatatgac gcgtatggaa
    17881 gtgcggagcc gagtaggaga ttctcacctt gggcatgtct ttacggatgg tccacaggac
    17941 aagggcggct tacgttactg tatcaatagc ctctctatcc gctttattcc caaagaccaa
    18001 atggaagaaa aaggctacgc ttatttacta gattatgttg attaatactc ttcgaaaatc
    18061 tcttcaaacc acgtcagcgt cgccttaccg tatgtagggt t
//
LOCUS       DAVBOG010000044        17886 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.044, whole genome shotgun sequence.
ACCESSION   DAVBOG010000044 DAVBOG010000000
VERSION     DAVBOG010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 17886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17886
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.044"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..771
                     /locus_tag="VQ865_001646"
                     /pseudo
     CDS             1..771
                     /locus_tag="VQ865_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            complement(1087..2061)
                     /gene="pta"
                     /locus_tag="VQ865_001647"
     CDS             complement(1087..2061)
                     /gene="pta"
                     /locus_tag="VQ865_001647"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HET3135958.1"
                     /translation="MEVFESLKANLVGKNARIVLPEGEEPRILQATKRLVKETEVIPV
                     LLGNPEKIKIYLEIEGIMDGYEVIDPQHYPQFEEMVSALVERRKGKMTEEDVRKVLVE
                     DVNYFGVMLVYLGLVDGMVSGAIHSTASTVRPALQIIKTRPNVTRTSGAFLMVRGTER
                     YLFGDCAININPDAEALAEIAINSAITAKMFGIEPKIAMLSYSTKGSGFGESVDKVVE
                     ATKIAHDLRPDLEIDGELQFDAAFVPETAALKAPGSTVAGQANVFIFPGIEAGNIGYK
                     MAERLGGFAAVGPVLQGLNKPVNDLSRGCNADDVYKLTLITAAQAVHQ"
     gene            complement(2105..3001)
                     /locus_tag="VQ865_001648"
     CDS             complement(2105..3001)
                     /locus_tag="VQ865_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001209987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3135959.1"
                     /translation="MRFEFIADEHVKVKTFLKKHEVSKGLLAKIKFRGGAILVNNQPQ
                     NATYLLDVGDYVTIYIPAEEGFETLEAIEHPLDILYEDDHFLVLNKPYGVASIPSVNH
                     SNTIANFIKGYYVKQNYENQQVHIVTRLDRDTSGLMLFAKHGYAHARLDKQLQKKSIE
                     KRYFALVKGDGHLEPEGEIIAPIARDEDSIITRRVAKGGKYAHTSYKIVASYGNIHLV
                     YIHLHTGRTHQIRVHFSHIGFPLLGDDLYGGSLEDGIQRQALHCHYLSFYHPFLEQDL
                     QLESPLPDDFSNLITQLSTNTL"
     gene            complement(2998..3816)
                     /locus_tag="VQ865_001649"
     CDS             complement(2998..3816)
                     /locus_tag="VQ865_001649"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HET3135960.1"
                     /translation="MKNTGKRIDLIANRKPQSQRVLYELRDRLKRNQFILNDTNPDIV
                     ISIGGDGMLLSAFHKYENQLDKVRFIGLHTGHLGFYTDYRDFELDKLVTNLQLDTGAR
                     VSYPVLNVKVFLENGEVKIFRALNEASIRRSDRTMVADIVINGVPFERFRGDGLTVST
                     PTGSTAYNKSLGGAVLHPTIEALQLTEIASLNNRVYRTLGSSIIVPKKDKIELIPTRN
                     DYHTISVDNSVYSFRNIERIEYQIDHHKIHFVATPSHTSFWNRVKDAFIGEVDE"
     gene            complement(3800..4471)
                     /locus_tag="VQ865_001650"
     CDS             complement(3800..4471)
                     /locus_tag="VQ865_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000171686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HET3135961.1"
                     /translation="MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTG
                     RVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRII
                     QERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYK
                     YQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDT
                     DEEYR"
     gene            4599..5168
                     /locus_tag="VQ865_001651"
     CDS             4599..5168
                     /locus_tag="VQ865_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000681289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HET3135962.1"
                     /translation="MKHLEIELKTLLKKDEYNRLKDQFTGVTPVLQTNYYIDTPDFEL
                     REKKVAMRIRTFEDWAELTLKVPQSVGNMEYNQKLQLKDAEDYLSKEELPQGLVLDEL
                     AKHGIQSKNWQVLGCLTTLRYEMKTAIGLMALDQSRYFDITDYELELEVENHEQGKQD
                     FRQFLEKNQISYQKAPSKLVRFVKSMKNS"
     gene            5281..6240
                     /locus_tag="VQ865_001652"
     CDS             5281..6240
                     /locus_tag="VQ865_001652"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HET3135963.1"
                     /translation="MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQ
                     VNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDR
                     IACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCD
                     KGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKA
                     ILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDS
                     VATKEKTPKNVCYITASELIGDAIVRIHERKPVSPLFAYNKKK"
     gene            6250..7365
                     /locus_tag="VQ865_001653"
     CDS             6250..7365
                     /locus_tag="VQ865_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000639661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HET3135964.1"
                     /translation="MIYLDNAATTPMSAVAISAMTKVMQETHGNPSSIHGHGRQAGKL
                     LREARQELAQLLRTKPQHIFFTSGGTEGNNTTIIGYCLRHQEQGKHIITTAIEHHAVL
                     ETIDYLVQHFGFEATIIQPENQEITAQQIQKALRDDTILVSTMFTNNETGNLLPIAEI
                     GQILKQHPAAYHVDAVQAIGKIPIHSEELGIDFLTASAHKFHGPKGIGFLYASSMDFD
                     SYLHGGDQEQKKRAGTENLPAIVGMVAALKEDLEKQEEHFQHVQNLETAFLAELEGIQ
                     YYLNRGKHHLPYVLNIGFPGQKNDLLLLRLDLAGISISTGSACTAGVVQSSHVLEAMY
                     GANSERLKESLRISLSPQNTVEDLQTLAKTLKEIIGG"
     gene            7370..7717
                     /locus_tag="VQ865_001654"
     CDS             7370..7717
                     /locus_tag="VQ865_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000863538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HET3135965.1"
                     /translation="MAFEKIIQLKNCRYDYTLSPSVKKFTLKDNTFFETKVGNYELTR
                     LLEKVPNSGEGFQLKIIINKEVTGAKINITDKFGLRLVDIFKSEDHHIHQEKFYFLMD
                     SLVERGVFTKSER"
     gene            7725..7940
                     /locus_tag="VQ865_001655"
     CDS             7725..7940
                     /locus_tag="VQ865_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000462494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4649 family protein"
                     /protein_id="HET3135966.1"
                     /translation="MFELTYKDCYHVERTLKYEDHEALMLTLSGCVTLPDTLYVTSLT
                     FRGQKVYQGLVGDLYRFLSHADFLHQN"
     gene            8023..8664
                     /locus_tag="VQ865_001656"
     CDS             8023..8664
                     /locus_tag="VQ865_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HET3135967.1"
                     /translation="MKDKQFAIPKATAKRLSLYYRIFKRFHAEKIERANSKQIAEAIG
                     IDSATVRRDFSYFGELGRRGFGYDVKKLMTFFADLLNDNSITNVMLVGIGNMGHALLH
                     YRFHERNKMKIIMAFDLDDHPEVGTQTPDGIPIYGISQIKDKIKDADVKTAILTVPSV
                     KSQEVANLLVDAGVKGILSFSPVHLHLPKDVVVQYVDLTSELQTLLYFMRKED"
     gene            8682..9371
                     /locus_tag="VQ865_001657"
     CDS             8682..9371
                     /locus_tag="VQ865_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3135968.1"
                     /translation="MKKPVIGITGNEKTHPDDDIMMSYAAKGFVEGVKDAGGIPIILP
                     IGDQEMACHYISLIDKLILTGGQNVDPKFYGEPKTIDSDDYHLQRDIFELALIKEAIK
                     QKKPIFSVCRGTQLFNVAMGGTLYQDIEDHWQDSSVEYTTQRLVTEPDTVLQEIYGEI
                     SHINSFHHQSIKDLAPNLKVVAHDPKDGIIEAVMSTDDVAFLGVQWHPELLFENRPKD
                     KKLFDYVVNEL"
     gene            complement(9368..10048)
                     /gene="radC"
                     /locus_tag="VQ865_001658"
     CDS             complement(9368..10048)
                     /gene="radC"
                     /locus_tag="VQ865_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000286923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HET3135969.1"
                     /translation="MYSISFQEDSLLPRERLAKEGVEALSNQELLAILLRTGTRQASV
                     FEIAQKVLNNLSSLTDLKKMTLQELQSLSGIGRVKAIELQAMIELGHRIHKHETLEME
                     SILSSQKLAKKMQQELGDKKQEHLVALYLNTQNQIIHQQTIFIGSVTRSIAEPREILH
                     YAIKHMATSLILVHNHPSGAVAPSQNDDHVTKLVKEACELMGIVLLDHLIVSHSNYFS
                     YREKTDLI"
     gene            complement(10091..12382)
                     /gene="pcrA"
                     /locus_tag="VQ865_001659"
     CDS             complement(10091..12382)
                     /gene="pcrA"
                     /locus_tag="VQ865_001659"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000992850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HET3135970.1"
                     /translation="MNALLNGMNDRQAEAVQTTEGPLLIMAGAGSGKTRVLTHRIAYL
                     IDEKLVNPWNILAITFTNKAAREMKERAYSLNPATQNCLIATFHSMCVRILRRDADHI
                     GYNRNFTIVDPGEQRTLMKRILKQLNLDPKKWNERTILGTISNAKNDLIDDVAYAAQA
                     GDMYTQIVAQCYTAYQKELRQSESVDFDDLIMLTLRLFDQNPDVLTYYQQKFQYIHVD
                     EYQDTNHAQYQLVKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPKAKVVL
                     LEENYRSTKTILQAANEVIKNNKNRRPKNLWTQNADGEQIVYYRADDELDEAVFVART
                     IDELSRSQNFLHKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDIIA
                     YLNLIANLSDNISFERIINEPKRGIGPGTVEKIRDFANLQNMSMLDASANIMLSGIKG
                     KAAQSIWDFANMMLDLREQLDHLSITELVESVLEKTGYVDILNAQATLESKARVENIE
                     EFLSVTKNFDDTTDVTEEETGLDKLSRFLNDLALIADTDSGSQETSEVTLMTLHAAKG
                     LEFPVVFLIGMEENVFPLSRATEDTDELEEERRLAYVGITRAEKILYLTNANSRLLFG
                     RTNYNRPTRFINEISSDLLEYQGLARPANTSFKASYSSGSISFGQGMSLAQALQDRKR
                     GAAPKSIQSSGLPFGQFTAGAKSASSEANWSIGDIALHKKWGEGTVLEVSGSGARQEL
                     KINFPEVGLKKLLASVAPIEKKI"
     gene            complement(12573..13378)
                     /locus_tag="VQ865_001660"
     CDS             complement(join(12573..13001,13004..13378))
                     /locus_tag="VQ865_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
                     /protein_id="HET3135971.1"
                     /translation="MNDEASKQLTDARFKRLVDVQRTTFEEMLAVLKTAYQLKHAKGG
                     RKPKLSLEDLLMATLQYVREYRTYEQIAADLGIHESNLIRRSQWVEVTLVQSGFTISR
                     TPLSSEDTVMIDATEVKTNRPKKQLANYSGKKKFHAMKAQAIVTSQGRIVSLDITVNY
                     CHDMKLFKMSRRNIGQAGKILADSGYQGLMKIYPQAQTPRKSSKLKPLTVEDKAYNHA
                     LSKERSKVENIFAKVKTFKMFSTTYRNHRKRFGLRMNFIAGIINHELGF"
     gene            complement(13758..14618)
                     /locus_tag="VQ865_001661"
     CDS             complement(13758..14618)
                     /locus_tag="VQ865_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013903404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl aminopeptidase"
                     /protein_id="HET3135972.1"
                     /translation="MITLKSAREIEAMDKAGDFLASIHIGLRDLIKPGVDMWEVEEYV
                     RRRCKEENFLPLQIGVDGAMMDYPYATCCSLNDEVAHAFPRHYILKDGDLLKVDMVLG
                     GPIAKSDLNVSKLNFNNVEQMKKYTQSYSGGLADSCWAYAVGTPSEEVKNLMDVTKEA
                     MYKGIEQAVVGNRIGDIGAAIQEYAESRGYGVVRDLVGHGVGPTMHEEPMVPNYGIAG
                     RGLRLREGMVLTIEPMINTGDWEIDTDMKTGWAHKTIDGGLSCQYEHQFVITKDGPVI
                     LTSQGEEGTY"
     gene            complement(14634..15911)
                     /locus_tag="VQ865_001662"
     CDS             complement(14634..15911)
                     /locus_tag="VQ865_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HET3135973.1"
                     /translation="MSKHQEILSYLEELPVGKRVSVRSISNHLGVSDGTAYRAIKEAE
                     NRGIVETRPRSGTIRVKSQKVAIERLTFAEIAEVTSSEVLAGQEGLEREFSKFSIGAM
                     TEQNILSYLHDGGLLIVGDRTRIQLLALENENAVLVTGGFQVHDDVLKLANQKGIPVL
                     RSKHDTFTVATMINKALSNVQIKTDILTVEKLYRPSHEYGFLRETDTVKDYLDLVRKN
                     RSSRFPVINQHQVVVGVVTMRDAGDKSPSTTIDKVMSRSLFLVGLSTNIANVSQRMIA
                     EDFEMVPVVRSNQTLLGVVTRRDVMEKMSRSQVSALPTFSEQIGQKLSYHHDEVVITV
                     EPFMLEKNGVLANGVLAEILTHMTQDLVVNSGRNLIIEQMLIYFLQAVQIDDILRIQA
                     RIIHHTRRSAIIDYDIYHGHQIVSKANVTVKIN"
     gene            complement(15904..16455)
                     /locus_tag="VQ865_001663"
     CDS             complement(15904..16455)
                     /locus_tag="VQ865_001663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3135974.1"
                     /translation="MNIWTKLAMFSFFETDRLYLRPFFFSDSQDFREIASNPENLQFI
                     FPTQASLEESQYALANYFMKSPLGVWAICDQKNQQMIGSIKFEKLDEIKKEAELGYFL
                     RKDAWSQGFMTEVVRKICQLSFEEFGLKQLSIITHLENEASQRVALKSGFSLFRQFKG
                     SDRYTRKMRDYLEFRYVKGEFNE"
     gene            complement(16471..17730)
                     /locus_tag="VQ865_001664"
     CDS             complement(16471..17730)
                     /locus_tag="VQ865_001664"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HET3135975.1"
                     /translation="MRKIVINGGLPLQGEITISGAKNSVVALIPAIILADDVVTLDCV
                     PDISDVASLVEIMELMGATVKRYDDVLEIDPRGVQNIPMPYGKINSLRASYYFYGSLL
                     GRFGEATVGLPGGCDLGPRPIDLHLKAFEAMGATASYEGDNMKLSAKDTGLHGASIYM
                     DTVSVGATINTMIAAVKANGRTIIENAAREPEIIDVATLLNNMGAHIRGAGTNIIIID
                     GVERLHGTRHQVIPDRIEAGTYISLAAAVGKGIRINNVLYEHLEGFIAKLEEMGVRMT
                     VSEDSIFVEEQSNLKAINIKTAPYPGFATDLQQPLTPLLLRANGRGTIVDTIYEKRVN
                     HVFELAKMDADISTTNGHILYTGGRDLRGASVKATDLRAGAALVIAGLMAEGKTEITN
                     IEFILRGYSDIIEKLRNLGADIRLVED"
BASE COUNT         5431 a         3900 c         3262 g         5293 t
ORIGIN      
        1 ctcgtatcat caaccaaaag attgctcaaa agttaattga aaagatttct atgactgata
       61 ttgcccatca gctttccatc tcaacttcaa ctgttattcg taagctcaat gattttcact
      121 ttgagcatga tttttcgcgt cttcctgaga ttatgtcttg ggacgttgaa acagtccggg
      181 gagtgactgt ttcaatcggg agatggagat gagctttatt gctcaggact ttgataagct
      241 caatatcata actgttcttg agagcagaac acaagccatc atccgaaatc ccatgaatac
      301 aaggctatca agcgctactg gaaactcatt caacaggata gccgtaaact gagtgataag
      361 cgattttatc gtcctacttt tcgtatgcat ttaaccaata aagagatttt agacaagctt
      421 ttgagctatt cacaagactt gaaacatcac tatcagctct atcaactctt gctgtttcac
      481 tttcagaata aggaaccgga gaaatttttc ggactcattg aggacaatct aaagcaggtt
      541 catcctcttt ttcagactgt ctttaaaacc tttctaaagg acaaagagaa aatcgtcaac
      601 gcccttcaac taccctattc aaacgccaaa ttggaagcga ccaataatct catcaaactt
      661 atcaagcgca atgcctttgg ttttcggaac tttgaaaact tcaaaaaacg gatttttacc
      721 gctctgaata tcaaaaaaga aaggacaaaa tttgtccttt ctcgagctta gcttttcttc
      781 aacccactac agttgacaaa gagccagaaa acgcataata gcaggtgtca agacacttaa
      841 tattatgcgt tttctcatga aaaaattctc ttttcatact catttaaaat caaaaaggga
      901 aattatcgtt ttacggacat acatattaca gatttctata ggtcgtgtat agacaggata
      961 tcatcgcttg gaagttttcc tttttgacac caatcagtaa tttagttctc aggaattaat
     1021 ggcagtgctt ttcgtacata gtttcataac tacagtatag catagtatat cgctttatag
     1081 ttttcactat tgatgaactg cttgagctgc tgtgatgagg gtcaacttgt aaacatcatc
     1141 tgcattacat ccacgagaaa gatcattaac tggcttgttt aaaccttgca aaacaggtcc
     1201 tacagccgca aagccaccca ggcgttcagc catcttgtaa ccgatatttc cggcctcgat
     1261 acctgggaag atgaagacat ttgcttgacc agctaccgta cttccaggag ctttcagagc
     1321 tgcagtttca ggaacaaagg ctgcatcaaa ttgcaactca ccatcgattt caaggtcagg
     1381 acgcaagtcg tgagcaattt tagttgcttc aacgacctta tcaacgcttt caccaaaccc
     1441 tgaaccttta gtagaatagc tcaacatggc aattttaggt tcgatgccaa acatcttagc
     1501 tgtgattgct gagttgatgg caatttcagc caaggcttct gcatctggat tgatgttaat
     1561 ggcacagtct ccaaataggt aacgttccgt accacgaacc atgaggaagg ctcctgaagt
     1621 acgagttaca tttggacgag ttttgatgat ttgtagagct ggacgaactg ttgaagctgt
     1681 tgagtgaatc gctcctgaca ccattccatc aaccaagccc aagtaaacca acatcacacc
     1741 aaagtagttg acatcttcaa ccaaaacctt gcgtacatct tcttcagtca ttttgccctt
     1801 gcgacgctcc accaaggcag aaaccatttc ttcaaattga ggataatgtt gagggtcgat
     1861 gacctcataa ccatccatga ttccttcaat ttcaagataa attttaattt tttcaggatt
     1921 tccaagcaaa acaggaatca cttctgtttc ttttactaag cgttttgttg cttgaagaat
     1981 acgaggctct tccccttcag ggagaacgat acgagcattt ttaccaacaa ggttggcttt
     2041 gagactttca aaaacttcca tgagttttct cctttaagat aataattata ctctgagaca
     2101 gtttttatag agtattagtt gataactggg taataaggtt actgaaatca tccggcaagg
     2161 gactttctaa ctgcaagtct tgctctaaaa atggatgata aaaggatagg taatggcaat
     2221 gcagagcctg acgttgaata ccatcttcca gactaccacc atacaaatca tctcccagca
     2281 aaggaaaacc gatatgagaa aaatggactc ggatttgatg ggttcgacca gtgtgcaggt
     2341 gaatatagac caagtgaata tttccataag aagctacaat cttgtatgaa gtatgggcat
     2401 actttccgcc tttagccact cgtctggtaa taatggaatc ttcatcacgc gcaatcggag
     2461 caataatttc cccttctggc tccaaatgtc catctccctt aaccaaagca aagtagcgtt
     2521 tctcgataga tttcttctgc aactgcttgt ctaatcgtgc atgggcataa ccgtgcttgg
     2581 caaagagcat caagccagaa gtgtccctat ctagtctggt aacaatgtga acctgctgat
     2641 tttcataatt ttgcttgaca tagtaaccct tgataaaatt ggcaatggtg ttagagtgat
     2701 tgacactagg aatagaagcc actccatagg gtttattcaa gactagaaag tggtcatcct
     2761 catagagaat atctaatgga tgctcaatag cctccaaggt ttcaaagcct tcctcagcgg
     2821 gaatgtaaat ggtaacgtag tctccaacgt ccaatagata cgttgcattt tgcggttgat
     2881 tattgaccag aatagctcca cctcgaaact taatcttagc cagcaatccc ttagaaacct
     2941 cgtgcttttt taaaaaggtc ttaaccttga catgttcatc tgcgataaat tcaaacctca
     3001 ttcatccacc tcaccgataa aggcatcctt aacacggttc cagaaactgg tatggctagg
     3061 agtcgcgaca aagtgaatct tatgatggtc gatttgatac tcaatacgct caatattacg
     3121 gaaagaataa acgctattgt caaccgaaat agtatgataa tcgtttcttg ttggaataag
     3181 ttcaatctta tccttcttag gcacaataat ggaagagccc agtgttcgat aaacacgatt
     3241 attaaggctg gcaatttccg ttaattgcaa agcttcaatg gtagggtgta aaacagcacc
     3301 gccaagagac ttgttatagg cagtactacc agtcggtgtc gaaactgtta gcccgtctcc
     3361 acgaaaacgt tcaaagggaa caccatttat tacaatatct gccaccatgg ttcgatcaga
     3421 cctgcggatg ctggcttcgt tgagtgctct gaaaatctta acttcaccat tttcaagaaa
     3481 gaccttcaca ttcagaacag ggtaagaaac ccttgcccca gtatctagct gcaaattagt
     3541 cactagcttg tccaactcaa aatcacgata atctgtatag aagcccaaat gtccagtatg
     3601 aagaccgata aagcggacct tgtcaagctg attttcgtac ttatgaaagg ccgacaagag
     3661 cataccatcc ccgccaatgg aaatgacaat atccggattg gtatcattga gtataaactg
     3721 atttctcttc aaacgatctc gcaattcata caaaaccctt tgactctgcg gttttctatt
     3781 ggctatcaga tcaattcgtt tacctgtatt cttcatctgt atcgtcactg tttcctacac
     3841 cgtcatttaa ttttctactc aaaggatcaa aaagtgcctg ggcttcttgg atatcatcac
     3901 gaatttcacc catttcttca tccaactgat gggcgattct agctgtaatt tccagtcgct
     3961 tcttaatctc atctgggaaa tccccttggt acttgtagtt gagagaatgt tctatcgttg
     4021 cccagaaatt catggccaaa gtacgaattt gaatttctgc caaaatagtc ttagctccat
     4081 tgatggtatc aaccgtatat tctactacca catgatagga acgatagcct gatgcttttc
     4141 tatgagtaat gtaatctcgc tcctgtatga ttcgcatatc ctgacgcttg tgcaaaatat
     4201 ccactacttc cttgacgtca tctacaaact gaaccatcac acgtaagcca gcaatatcct
     4261 gcaaatcgtg ttccaaggtc gcataagtaa tgccacgacg agccattttt tctttgatgc
     4321 tctcaattgg cttgactcga ccggtcacaa actcaattgg agaatgctta ttttgcttac
     4381 gatattgctt acgaatacca cgaagtttaa tctttaactc accaacagct tgaatgtaag
     4441 gatctagaaa ttcttcccat tctaaggtca tatattctcc cttgttctca tattatccgt
     4501 caaaaatatc tttgattttt tctccagatt catatacaat aaatacaatg cttattatac
     4561 cataaatccg ctttcaacga taaaaaaagg taagaaaaat gaaacattta gaaattgaat
     4621 tgaaaacact attgaaaaaa gatgaataca atcgtctaaa agaccagttc acaggtgtca
     4681 ctcctgttct tcaaacaaat tactacatcg acacgcctga ttttgaactg cgagaaaaga
     4741 aagtcgctat gcgcattcga acctttgaag actgggctga gttgacactc aaagtcccgc
     4801 agagtgttgg aaacatggaa tacaaccaaa aattgcaact aaaagatgct gaggactatc
     4861 tgagtaagga agaacttcct caaggactag tactggatga attggcgaaa catggtatcc
     4921 aaagtaagaa ctggcaggtt cttggttgtc taacaacgct tcgctatgaa atgaaaacag
     4981 ctattggtct catggcactg gatcagagcc gatactttga tataacagat tacgaattgg
     5041 agcttgaagt ggaaaatcat gagcaaggca aacaggattt ccgacaattt ttagagaaaa
     5101 atcagatttc ctaccaaaaa gctccttcaa aattggttcg atttgtcaaa agtatgaaaa
     5161 atagctgaaa taatctccat tttttggtaa aatagaaaag ataaaaatac acaaatccca
     5221 gttcatatat gtaaggtaaa tataactagg atttataaag tttacagagg acggtctata
     5281 atgtcagata gaaaaaacat gaaacttttc gcactcaact ctaaccaaga gattgcacaa
     5341 aaaattgccc aagctgttgg tgtcccactt ggaaaactat catcacgtca attttcagac
     5401 ggagaaatcc aagtaaatat cgaagaaagt gtccgtggtt atgatgttta catcatccaa
     5461 tcaacaagtt tccctgtcaa caaccaccta atggaattgt taatcatggt cgatgcttgt
     5521 gtgcgtgcaa gtgcccacag tatcaacgtt gtccttccat attttggcta tgcacgtcaa
     5581 gaccgcattg cttgtcctcg tgagccactt acagcaaaac tagttgccaa tatgctggtt
     5641 aaggctggag ttgatcgtat cctgactctt gatttgcatg ccgttcaggt tcaaggtttc
     5701 tttgatattc cagtggataa tcttttcact gttcccctat tcgcaaaaca ttactgcgat
     5761 aaaggattgc ttggttcaga tgttgttgtc gttagcccta aaaattcagg tgtcaaacgt
     5821 gcgcgtagcc tggctgaata tcttgatgct cctatcgcca ttatcgacta ccctcaagac
     5881 gatgcaactc gtaacgaagg ttatattatt ggtgatgttg aaggtaagaa agctatcttg
     5941 attgatgata ttttaaatac aggacgtacc ttctctgaag cttctaaaat cgttgaacgt
     6001 gaaggagcta cagaaattta tgctgtttct agccacggtc tcttcgtcga gggagctgct
     6061 gagcttcttg acaatactaa tattaaagaa attcttgtga ctgattcagt agcaacaaaa
     6121 gaaaaaactc ctaaaaatgt atgctatatc actgctagtg agttaattgg tgatgctatc
     6181 gtacgtattc acgaaagaaa accagtcagc ccactctttg cctacaataa aaagaaataa
     6241 ggtgattctt tgatttattt ggacaatgct gcaacgactc ctatgtcagc agttgctatt
     6301 tcagctatga ccaaggttat gcaagaaacc cacggaaatc cttctagtat tcatggtcat
     6361 ggtcgtcaag ctggcaaact cttgcgagaa gcccgtcagg aactagccca gttactaagg
     6421 acaaaacctc aacatatctt tttcacttct ggtgggactg aaggcaataa tactaccatc
     6481 attggctact gtcttcgtca ccaagaacaa ggaaaacata tcatcacaac tgccatcgag
     6541 caccatgctg tccttgaaac aattgattac ttggttcaac actttgggtt tgaagcaacc
     6601 attatccagc cagaaaatca agaaatcaca gcccagcaaa ttcaaaaggc tttacgtgac
     6661 gatacgattt tggtttctac catgtttacc aataatgaga caggaaacct actgcccatc
     6721 gctgaaattg gccaaatact caagcaacac cctgctgcct atcatgttga tgcagttcag
     6781 gctattggta aaatcccaat tcattcagaa gaattgggca ttgattttct cactgcttct
     6841 gcccacaaat tccatggtcc taagggaatc ggttttctct acgcatctag catggacttt
     6901 gattcctatc tacatggcgg agaccaggaa cagaaaaaac gtgcaggaac tgaaaatctg
     6961 cctgctatcg taggcatggt tgcagcccta aaagaagacc tagaaaaaca agaagaacat
     7021 tttcaacatg tacaaaatct agaaactgcc tttctggcag agctggaggg cattcagtat
     7081 tacttgaata gaggaaaaca tcatctccct tatgttctca atattggatt tcctggtcag
     7141 aaaaatgacc tcttactcct tcggctagat ttagctggaa tttcaatctc tactggctca
     7201 gcctgtactg caggcgttgt ccaatccagc catgttcttg aagccatgta tggcgcaaat
     7261 tcagaacgct tgaaggaatc ccttcgcatc agtttgtcgc cacaaaatac cgttgaagac
     7321 ctacaaaccc tcgcaaaaac cttaaaagaa attatcggag gttagccata tggcatttga
     7381 aaaaatcatt cagttaaaaa attgtcgtta cgattacact cttagccctt ctgttaaaaa
     7441 attcaccctc aaagataaca ccttttttga aactaaggtt ggtaactatg aactgactcg
     7501 ccttttggaa aaagtgccaa acagcggtga aggcttccaa ctcaaaatca tcattaacaa
     7561 ggaagttaca ggggctaaaa tcaatatcac tgataagttt ggccttcgtc tagttgatat
     7621 tttcaaatca gaagaccacc atattcatca ggaaaaattc tacttcctca tggatagctt
     7681 ggtagaacgt ggtgtcttta caaaatcgga aagatagagc caaaatgttt gaactgacct
     7741 ataaggactg ctatcatgta gagcgtactc tcaagtatga ggatcatgag gctctcatgt
     7801 tgactttgtc aggatgtgta accttaccag atacacttta tgtgacttct ctgactttta
     7861 ggggccaaaa agtttatcag ggtctggtcg gagacctcta ccgttttcta tctcatgcag
     7921 attttttaca tcaaaactaa gatttttctt agttttttct tatttttgtt gattttttca
     7981 caatgtttct ataaaataga agaatagaaa ggttgtgatt ttgtgaaaga taaacagttt
     8041 gctattccaa aagctacagc aaaaagactc tctctctact atcgaatttt taagagattt
     8101 catgcagaaa agattgaacg tgccaactct aagcaaattg cagaggctat cggtattgat
     8161 tcagcgaccg tacgtcgtga tttttcctat tttggtgaac ttggtcgtcg tggttttgga
     8221 tatgatgtca aaaaactaat gacatttttt gccgatttgc tcaatgacaa ctctattacc
     8281 aatgtcatgc tggttggtat tggaaatatg ggccatgccc ttctccacta ccgcttccac
     8341 gaacgtaaca agatgaagat tatcatggcc tttgacctag atgaccatcc tgaagtcggt
     8401 acccaaactc ctgacgggat tcccatttac ggaatttctc agatcaagga taaaatcaag
     8461 gatgctgatg tgaagactgc tatcctaact gttcccagcg tcaagtcaca agaggttgct
     8521 aatctcttgg ttgatgctgg tgtgaaagga attctcagtt tttcaccagt ccatctgcat
     8581 ttaccaaaag acgtggtcgt tcagtatgtc gatttgacaa gtgaactcca aaccctcctc
     8641 tacttcatgc gaaaagagga ttagaaagcg aaaatcattt tatgaaaaaa ccagttattg
     8701 ggattacagg aaacgaaaaa actcatccag atgatgacat catgatgagc tacgcagcaa
     8761 aaggctttgt tgaaggcgtt aaagatgctg gagggattcc catcatccta ccgattggtg
     8821 atcaagaaat ggcctgccac tatatcagtt tgattgacaa gctcatcttg acaggtgggc
     8881 aaaatgtcga tccaaaattc tatggcgaac ccaaaaccat tgatagcgat gactatcacc
     8941 ttcaaagaga tatcttcgaa ctggccctca tcaaggaagc tattaaacag aaaaagccca
     9001 ttttctctgt ctgccgtggt acccaactct ttaacgttgc catgggtgga actttgtacc
     9061 aagatatcga agaccattgg caggattctt ctgttgagta cacaactcaa cgcttggtga
     9121 cagaaccaga taccgttctc caagaaatct atggagaaat ctctcatatc aactccttcc
     9181 accaccagag catcaaggac ttagcaccaa atttaaaagt tgtggctcat gatcctaaag
     9241 atggtatcat tgaggctgtc atgagtacgg atgatgtcgc ctttctcggt gtccaatggc
     9301 atccagaact tctttttgaa aatcgtccca aagataaaaa actctttgac tatgtcgtta
     9361 atgaacttta gattaaatct gtcttttcac gataactaaa gtaattagaa tgagagacaa
     9421 tcaaatggtc caagagaaca atccccatca gttcgcaggc ttctttaaca agtttagtga
     9481 catgatcatc attttggcta ggcgctaccg ctcctgaagg atgattgtgg accaagataa
     9541 gagaagtcgc catatgcttg attgcatagt gcagaatctc tcgcggttca gcgatactac
     9601 gagttacaga accgataaaa atggtctgct gatggatgat ttgattttga gtattgagat
     9661 agagtgccac caggtgctct tgttttttat cccctaattc ctgctgcatc ttcttggcca
     9721 acttttgact gctgagaata ctttccattt caagagtctc gtgtttgtga atacgatgcc
     9781 ccagttcaat catagcttgt aattctatgg ccttaacacg cccaatacca gacaaactct
     9841 gcaattcctg cagggtcatt tttttcaaat ccgttaggct tgaaagattg ttcaagactt
     9901 tttgggcaat ttcaaaaacg ctagcttgac gtgttcctgt cctgagtaaa atagctagca
     9961 actcttggtt actaagcgct tcaactcctt ccttggccag cctttctctt ggtaatagtg
    10021 aatcttcttg gaatgaaata ctgtacataa aaatcctcct cactttatta ttcgtgagaa
    10081 ggatggaaaa ttagattttt ttctcaattg gagccacact ggctaaaagt tttttcaaac
    10141 ctacttctgg gaaattgatt ttcaattcct gcctagcacc gctacctgaa acttccagaa
    10201 cagttccctc tccccatttc ttgtggagag caatgtcacc aatggaccaa tttgcctcgc
    10261 tagatgctga ttttgcgcca gctgtaaatt gaccaaatgg aagaccgctt gactggattg
    10321 attttggggc agcaccgcgt ttacggtctt gaagagcctg agccaaactc ataccttgac
    10381 caaaggaaat actaccactg ctatatgatg ccttaaagct tgtatttgca ggacgagcca
    10441 gaccttgata ctcaagcaag tctgaactga tttcgttaat aaaacgagtc ggacggttat
    10501 aattggtacg accaaaaagc aagcgtgagt tggcattggt cagatagaga attttctctg
    10561 cacgcgtgat acctacatag gctagacggc gctcttcttc taattcatct gtatcttcag
    10621 tcgcacgact aagtggaaag acattttctt ccatcccaat caaaaagaca actggaaatt
    10681 cgagaccttt ggcagcatgc agggtcatca aggtcacttc tgatgtctcc tgactacctg
    10741 aatctgtgtc ggcaatcaaa gccaagtcat ttaagaaacg actcagtttg tccagaccag
    10801 tttcctcttc tgtcacatca gtggtgtcat caaagttctt cgtaacagaa agaaactctt
    10861 cgatattttc aacccgtgcc ttgctttcta gagtcgcttg ggcgttaaga atatcgacat
    10921 aacctgtttt ttctaggacg gactcaacca actctgtaat gcttaagtgg tctagctgct
    10981 cccgcaaatc aagcatcata ttggcaaaat cccagataga ttgggctgcc ttacccttga
    11041 taccagacaa cataatatta gcagaagcat ccagcataga catattttgc aaatttgcaa
    11101 aatcacggat tttctcaact gtacctggac caattccacg tttaggctcg ttgataatac
    11161 gctcaaaact aatattgtca ctcaaattag caataaggtt gagataagca ataatatcgc
    11221 gaatttcctt acggctgtag aatttggttc cgccaaccat ggtataagga atgttagact
    11281 tgagcagggc ttcctcaatt gtacgggact gggcattagt ccgatagaga actgcaaaat
    11341 ccttatgaag gaagttttga ctgcgactaa gttcatcgat ggttctggct acaaatacag
    11401 cctcatccag ctcatcatcg gcacgatagt aaacgatttg ctccccatca gcgttttgag
    11461 tccagagatt tttaggacgg cgatttttat tgtttttaat aacctcgttg gccgcttgga
    11521 gaatggtttt ggttgagcgg taattttcct ccaacaaaac aaccttggct ttggggtaat
    11581 ccttttcaaa gtccaagata ttctgcatat cagcaccacg ccaaccgtag atagactggt
    11641 ccgcatcccc aaccacacag atatttttaa aacgggaagc caagagtttg accaattggt
    11701 actgagcgtg gttggtatct tggtactcat caacgtggat gtattggaat ttttgctggt
    11761 agtaggttaa aacatcagga ttttgatcaa agagacgcaa ggtcagcata atcaaatcat
    11821 caaagtcaac ggattcagac tgacgaagtt ctttttgata ggctgtataa cactgggcca
    11881 caatttgcgt atacatatcg ccagcttggg cagcataagc aacatcatca atcaaatcat
    11941 tcttagcatt ggaaatggtc cccaaaatag ttcgttcatt ccatttttta ggatccaagt
    12001 tcaactgttt gagaatacgt ttcatgagcg ttcgctgttc accaggatcc acaattgtaa
    12061 aattacgatt gtagccaata tggtccgcat cgcgacgcaa aatacgcaca cacatggagt
    12121 ggaaggtcgc aatcagacag ttctgagtag ctggattgag actataagca cgctctttca
    12181 tctcacgcgc agccttgttg gtaaaggtaa tggccaagat attccaagga ttgaccagct
    12241 tttcatcaat caaataagcg atacggtggg ttaaaacacg agtctttcca gaaccagccc
    12301 ctgccatgat tagcaaggga ccttctgtcg tttgcaccgc ctcagcctga cggtcattca
    12361 ttccatttaa taatgcgttc atcttctctt ccttactctt gaagtcaata tttctattat
    12421 atcagaaatc agggaaaata gaaactttac ggggagtagc aaaatatagt ggattgaaac
    12481 tagaatacta cactgtgggt ttctaaaaca ctcgactttt cacccaattt tttcataaac
    12541 tagctcaata cctcaataga cttcctgcaa aactagaatc ctagttcatg attgataata
    12601 ccagcaataa aattcattcg taatccgaag cgtttacgat gatttcgata agttgttgaa
    12661 aacattttaa acgtttttac tttggcaaag atgttctcaa ccttgcttct ctccttagat
    12721 agcgcatggt tataagcctt atcttcaact gttagcggct tgagtttgct ggatttacgt
    12781 ggagtttgtg cttgaggata tattttcatg agcccttgat aaccactgtc agccaagatt
    12841 ttaccagctt gtccgatatt tctgcgactc attttgaaca acttcatatc atgacaatag
    12901 ttcacagtga tatccaaaga aacaattctt ccttgacttg tgacaatcgc ttgagccttc
    12961 atagcgtgaa atttcttttt accagaataa ttggctagtt gattttttta gggcgattgg
    13021 tttttacttc cgtcgcatca atcattaccg tgtcctcaga actgagagga gttcttgaaa
    13081 tcgtaaaacc actttgaaca agagttactt caacccattg gctccgacgg attaagttgc
    13141 tttcgtgaat accaagatca gccgcaattt gttcataagt tcgatattct cgcacatatt
    13201 gaagagtggc cataagaagg tcttctaggc ttaatttagg ttttcttcca ccttttgcat
    13261 gtttaagttg ataagctgtt tttaatacag ctaacatctc ttcaaaagtg gtacgctgaa
    13321 catcaacaag acgcttaaat cgtgcatcag ttagttgttt acttgcttca tcattcatag
    13381 aactactata ccatgttttg tttcgcagga agtataatat aaaaaaataa atttaagatt
    13441 ggcaatacga acgttaaaca gaattccatt tctcttttta gaatcaaaac gacaatattg
    13501 tggaatctct acaggaacaa tagactgcga cactaaaata tcctccctta gttttacttt
    13561 actaatagta tataggagga gagccctgaa tcctagaccc tttgttatga tgcgcttaca
    13621 aacagagttg gaaaaaatct taaaagcaga aaaacgcatg atatcagccc ctaacacttg
    13681 atacaatgcg ttttattatg aaaagatcta ctggattttt tatcaaaata aacttccagt
    13741 agtcttttca ctttttatta ataagttcct tcttcacctt ggctagtcaa gataacaggt
    13801 ccatctttcg taatgacaaa ttggtgttca tactgacatg acaatccacc gtcaatggtc
    13861 ttatgcgccc aaccagtttt catatctgta tcaatttccc aatcgcctgt attgatcatt
    13921 ggttcaatgg ttaagaccat tccttcacga agacggagtc cacgacctgc aataccatag
    13981 ttaggaacca ttggttcttc gtgcatagtt gggccaacac catgaccaac caaatcacgc
    14041 actacaccgt aaccacgact ttcagcgtat tcttgaatag ccgcaccgat atcaccgata
    14101 cgatttccaa caacagcttg ctcaataccc ttgtacatag cttctttggt tacatccatc
    14161 aagtttttga cttcttcgga cggtgtacca acagcataag cccaacatga gtctgctaaa
    14221 ccaccagaat agctctgagt atattttttc atttgttcaa cattgttgaa gtttaatttt
    14281 gagacattca ggtcagattt agcaatggga cctcccaaaa ccatatcaac tttgagcaaa
    14341 tcaccatctt tcaagatata atgacgaggg aaagcgtgag ccacttcatc gttaagagag
    14401 caacaggtag cataaggata gtccatcatg gcaccgtcaa ccccaatctg aagtggaagg
    14461 aaattttctt ctttacaacg acggcggaca tattcttcaa cttcccacat atctacgcct
    14521 ggcttaatca aatcacgtaa gcctatatga atacttgcta gaaaatcacc agccttgtcc
    14581 atagcttcga tttcacgagc tgattttaat gttatcatct tttctcctag tttctaatta
    14641 attttaacag tcacatttgc ttttgaaaca atctggtgac catgataaat atcgtaatca
    14701 attatagctg accgtctcgt atgatgaata atccgtgcct gaatgcgcaa tatatcatct
    14761 atctgaacag cctgcaaaaa gtagatcagc atctgctcga taatgagatt gcgaccacta
    14821 ttaacaacta aatcttgggt catgtgggtc agaatttctg ccaatacacc attagccaaa
    14881 actccatttt tttctagcat aaagggttcc actgtaatga ctacttcatc atggtgataa
    14941 gagagctttt gtccaatctg ctcagaaaaa gttggtagag ccgaaacttg ggaacggctc
    15001 atcttctcca tgacatctcg tcgcgtcaca acgccaagca aagtttgatt gcttcgaaca
    15061 actggtacca tttcaaagtc ttctgcgatc atccgttgac tcacattggc aatatttgtc
    15121 gataatccaa ccaaaaatag actacgagac ataaccttat caattgtcgt gcttggtgat
    15181 ttatcaccag cgtctctcat ggttacaacg ccaacaacga cctgatgttg attgataaca
    15241 gggaaacggc tgctacgatt cttacgaacc aagtccaaat aatctttaac tgtatctgtc
    15301 tctctcagaa aaccatactc atgactaggg cgataaagtt tctcaactgt cagaatatca
    15361 gtcttgattt ggacatttga caaggcttta ttgatcatgg tcgcgacggt aaaggtatca
    15421 tgcttacttc ttagaacagg aatccctttt tgattggcca gtttaagcac atcatcatga
    15481 acctgaaatc cccctgtaac cagaactgca ttttcatttt ccaaggctag caactgaata
    15541 cgggttcggt ctccgacaat caagagcccc ccatcatgaa ggtaagacaa gatattttgt
    15601 tcagtcatgg caccaattga aaacttacta aattctctct ctaaaccttc ttgcccagcc
    15661 agaacctcag aagaagtcac ttctgcaatt tcagcaaacg ttaatctctc tatagcaact
    15721 ttctgggatt taacacgaat tgttccactt ctaggacggg tctccacaat tccacggttt
    15781 tcagcttctt taatagcccg ataggctgtt ccatcactaa ctcctagatg attcgaaatg
    15841 ctacgaacac tgaccctttt acctactggt aattcctcca aatagcttag aatttcctga
    15901 tgcttactca ttgaactctc cttttacata ccgaaattca agataatccc gcatttttct
    15961 tgtgtaacga tcacttccct taaactgacg gaacaaacta aatccagact taagagcaac
    16021 tctttggcta gcttcatttt caaggtgggt aatgatagat aattgtttta agccaaattc
    16081 ctcaaaagaa agctgacaaa tttttctaac aacctctgtc ataaatcctt gcgaccaagc
    16141 atcttttctc aaaaaatagc caagctcagc ttcttttttg atttcatcta acttctcaaa
    16201 tttaatagaa ccaatcattt gttgattttt ctggtcacaa attgcccaca ctcccaaagg
    16261 ggacttcata aagtaattgg ccagtgcata ttgactttct tccagacttg cctgcgttgg
    16321 gaaaataaat tgaagatttt ctggatttga agctatctcg cggaagtcct gactatcact
    16381 aaaaaagaaa ggacgcaaat acaagcgatc cgtttcaaaa aaagaaaaca ttgctaattt
    16441 ggtccaaata ttcataaaca cctctacggt ttaatcctca acaagtctaa tatccgctcc
    16501 taaattacgt aatttttcga taatatcaga ataaccacgt aagataaact cgatattggt
    16561 aatttcagtt ttaccttcag ccataagccc agcaatgact agtgcagccc cagctcttaa
    16621 gtcggtcgct ttaacactgg ccccacgtaa atcacgtcca cccgtgtaca aaatatgacc
    16681 atttgttgtc gaaatatccg catccatctt tgctagttca aaaacatgat ttacacgttt
    16741 ttcgtaaatc gtatcgacaa ttgtaccacg accattcgct cttagtaaaa gaggggtaag
    16801 cggttgttgc aaatcagttg caaagcctgg gtaaggagct gtcttaatat tgattgcttt
    16861 caaattagac tgttcctcga caaaaatgct gtcttcagat acagtcattc tcactcccat
    16921 ttcttccaac ttagcaataa acccttccag gtgttcgtaa agaacattat ttatacgaat
    16981 tcctttacca actgcagcag ctaaagatat atatgttcca gcttcaatgc ggtctggaat
    17041 cacctgatga cgtgtcccat gtaatctttc aacaccatca ataatgatga tattagttcc
    17101 tgccccacgg atatgggcac ccatattatt caagagagta gctacatcaa taatctcagg
    17161 ttcacgggct gcattttcaa taatagtacg accatttgct ttaaccgcag caatcatcgt
    17221 attaatcgtt gctcccacac taaccgtatc catgtaaata cttgcaccat gaagtcctgt
    17281 atctttagca gataacttca tgttatctcc ctcgtagcta gcagtggcac ccatagcttc
    17341 aaacgcctta aggtgtaagt caatcggacg aggaccaaga tcacatcctc ccggtagacc
    17401 aactgtcgct tcaccaaaac ggcctaagag gctcccataa aaatagtaag atgcacgaag
    17461 actgttaatt ttaccataag gcattggaat attttgaaca cctcttggat caatctccaa
    17521 gacatcgtca taacgcttaa cagtagctcc catcaattcc atgatttcga caagactggc
    17581 tacatccgaa atatctggaa cacaatccaa agtcaccaca tcatcagcca agataatagc
    17641 tggaattaag gccacaacac tatttttagc accactaata gtaatttcac cttgcagtgg
    17701 taatccacca ttgataacaa tttttctcat tctaagtttt caatactctt tcaagatttc
    17761 taataaggtc ttcaaaataa agtatatcat aaatttatcc ttttttccat ccttttcaat
    17821 tttattggat aaatcagagt tgacgagtta gtaactgaat tactaatact caataaaaat
    17881 caaaga
//
LOCUS       DAVBOG010000045        16933 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.045, whole genome shotgun sequence.
ACCESSION   DAVBOG010000045 DAVBOG010000000
VERSION     DAVBOG010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16933)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16933)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16933
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.045"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..211
                     /locus_tag="VQ865_001665"
     CDS             <1..211
                     /locus_tag="VQ865_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3135976.1"
                     /translation="PRKSSKLKPLIAEDKAYNHALSKDRSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLSAGIINHELGF"
     gene            260..724
                     /locus_tag="VQ865_001666"
     CDS             260..724
                     /locus_tag="VQ865_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose epimerase"
                     /protein_id="HET3135977.1"
                     /translation="MGGHPGFNCLLLDDEVYEDYYLEFEKEEICSVPRPFPETGMLDF
                     QDRSPWLEGQKEIDLSYDLFSTDAVTLDELQSRTIALRSLKHDKGLKVHFAEFPNLII
                     WSTLNKGPFITFEPWSGLSTFLEEGDHLEDKKNVCLLEANQVEELGFEIEVL"
     gene            882..1307
                     /gene="lacA"
                     /locus_tag="VQ865_001667"
     CDS             882..1307
                     /gene="lacA"
                     /locus_tag="VQ865_001667"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005590669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HET3135978.1"
                     /translation="MSIVIGADAAGLRLKEVVKDFLEKENFHLVDVTAEGQDFVDVTL
                     AVAAEVNKEEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     MGAQLVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            1338..1853
                     /gene="lacB"
                     /locus_tag="VQ865_001668"
     CDS             1338..1853
                     /gene="lacB"
                     /locus_tag="VQ865_001668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002994294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HET3135979.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPI
                     FGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNAN
                     VIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHLESHNAQQTDANFFTEF
                     LEKWDRGEYHD"
     gene            1864..2793
                     /locus_tag="VQ865_001669"
     CDS             1864..2793
                     /locus_tag="VQ865_001669"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000604270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HET3135980.1"
                     /translation="MILTVTMNPSIDISYPLDELKIDTVNRVVDVTKTAGGKGLNVTR
                     VLSEFGDSVLATGLVGGKLGEFLVEHIDNQVKKDFFSIQGETRNCIAILHGDNQTEVL
                     EKGPEVLEQEGQDFLEHFKKLLESVEVVAISGSLPAGLPVDYCASLVELANQAGKPVV
                     LDCSGAALQAVLESPHKPTVIKPNNEELSQLLGREVSEDLDELKEVLQEPLFAGIEWI
                     IVSLGANGTFTKHGDTFYKVDIPRIQAVNPVGSGDSTVAGISSGLLHKESDAELLIKA
                     NVLGMLNAQEKMTGHVNMANYQALYDQLIVKEV"
     gene            2795..3775
                     /gene="lacD"
                     /locus_tag="VQ865_001670"
     CDS             2795..3775
                     /gene="lacD"
                     /locus_tag="VQ865_001670"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001229146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HET3135981.1"
                     /translation="MALTEQKRVRLEKLSDENGIISALAFDQRGALKRLMAQHQTEEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDEKAGLLLAYEKTGYDTTSTK
                     RLPDCLDVWSAKRIKEEGADAVKFLLYYDVDSSDELNQEKQAYIERIGSECVAEDIPF
                     FLEILAYDEKIADAGSVEYAKVKPHKVIGAMKVFSDPRFNIDVLKVEVPVNIKYVEGF
                     AEGEVVYTREEAAAFFKAQDEATNLPYIYLSAGVSAKLFQDTLVFAHESGANFNGVLC
                     GRATWAGSVEAYIKDGEAAAREWLRTTGFENIDELNKVLQTTATSWKERV"
     gene            4009..4845
                     /locus_tag="VQ865_001671"
     CDS             4009..4845
                     /locus_tag="VQ865_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000285719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator"
                     /protein_id="HET3135982.1"
                     /translation="MYRILNPMNHNVSLVRNDKGEEVIVIGKGIAFGKKKGDLIAENQ
                     VEKIFRMKTEESRENFMALLKDVPLDFITVTYEIIDKLSKKYHYPIQEYLYVTLTDHI
                     YCSYQALTQGRYKDSNLPDISAKYPVAFQIANEAFEIYRQKLADHFPEDEIIRIAYHF
                     INAEGENEVELVESIDKRKEILRNVEEVLTDYAIQRTKKNNHFYDRFMIHLNYFLDYL
                     DRSRDDNQSLLDMEDHIKQSYPKAFEIGSKIYDVITQHTGLDLYKSERVYLVLHIQRL
                     LS"
     gene            4881..5198
                     /locus_tag="VQ865_001672"
     CDS             4881..5198
                     /locus_tag="VQ865_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009730102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3135983.1"
                     /translation="MNREEVTLLGFEIVAYAGDARSKLLEALKAAEAGDFEKADALVE
                     EAGSCIAEAHHAQTSLLTKEASGEDLAYSVTMMHGQDHLMTTILLKDLMHHLIELYKR
                     GVK"
     gene            5198..6889
                     /locus_tag="VQ865_001673"
     CDS             5198..6889
                     /locus_tag="VQ865_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001037357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HET3135984.1"
                     /translation="MNKLIAFIEKGKPFFEKLSRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAFVPNSWGFKWSDEVVAFLMKPYSYSMGILALLVAGTTAKSLTDSVNRSMEKTNQ
                     INYMSTLLAAIVGLLMLAADPIESGLATGFLGTKGLLSAFLAAFVTVAIYKVCVKNNV
                     TIRMPDEVPPNISQVFKDVIPFTLSVVSLYALDLLARHFVGSSVAESIGKFFAPLFSA
                     ADGYLGITIIFGAFAFFWFVGIHGPSIVEPAIAAITYANAEVNLNLLQQGMHADKILT
                     SGTQMFIVTMGGTGATLVVPFMFMWLTKSKRNRAIGRASVVPTFFGVNEPILFGAPLV
                     LNPIFFIPFIFAPIANVWIFKFFIETLGMNSFTANLPWTTPAPLGLVLGTNFQVLSFI
                     LAALLIVVDVVIYYPFLKVYDEQILEEERSGKSNDELKEKVAANFNTAKADAILEKAG
                     VDAAQNTITEETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGGYGAHREMLPE
                     FDLVILAPQVASNFEDMKAETDKLGIKLAKTEGAQYIKLTRDGKGALAFVQEQFD"
     gene            7104..8510
                     /gene="lacG"
                     /locus_tag="VQ865_001674"
     CDS             7104..8510
                     /gene="lacG"
                     /locus_tag="VQ865_001674"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HET3135985.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYNRYPVDLKLAEEYGVNGIRISIAWSRIFPTGYGQVNVKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEALHSNGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPLDPKNPADVRAAELEDIIHNKFILDATYLGRYSAETMEGVNHILSVNGGSLDL
                     REEDFTTLEAAKDLNDFLGINYYMSDWMEAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     VAPDYVPRTDWDWIIYPQGLYDQIIRVKKDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKQHLEILSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFETQERY
                     PKKSAHWYKKVAETQIID"
     gene            8600..8812
                     /locus_tag="VQ865_001675"
     CDS             8600..8812
                     /locus_tag="VQ865_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HET3135986.1"
                     /translation="MNFEKCSQIPCLTSEELKSLGKWYVSTGKEWICHSDDELEEFKN
                     LFLNFINPEEWDTISFDSDFMPFQQS"
     gene            complement(9091..9852)
                     /locus_tag="VQ865_001676"
     CDS             complement(9091..9852)
                     /locus_tag="VQ865_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000917571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3135987.1"
                     /translation="MLKQEKLTKILEIVNSKGTITVKQIMDEIAVSDMTARRYLQELA
                     DKDLLIRVHGGAEKLRTNSLLTNERSNIEKQALQTAEKQEIAHFAGSLVEERETIFIG
                     PGTTLEFFARELPIDNIRVVTNSLPVFLILSERKLTDLILIGGNYRDITGAFVGTLTL
                     QNLSNLQFSKAFVSCNGIQNGALATFSEEEGEAQRIALNNSNKKYLLADHSKFNKFDF
                     YTFYNVSNLDTIVSDSKLSDSILFKLSKHIKVIKP"
     gene            complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ865_001677"
     CDS             complement(10034..10996)
                     /gene="nrdF"
                     /locus_tag="VQ865_001677"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004253599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HET3135988.1"
                     /translation="METYYKAINWNAIEDVIDKSTWEKLTEQFWLDTRIPLSNDLDDW
                     RKLSNKEKDLVGKVFGGLTLLDTMQSETGVQALRADIRTPHEEAVFNNIQFMESVHAK
                     SYSSIFSTLNTKAEIEEIFEWTNTNPYLQKKAEIVNEIYLNGSPLEKKVASVFLETFL
                     FYSGFFTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEEEQEKLK
                     EWMYDLLYTLYENEEGYTESLYDGVGWTEEVKTFLRYNANKALMNMGQDPLFPDSAED
                     VNPIVMNGISTGTSNHDFFSQVGNGYLLGEVEAMQDDDYNYGLD"
     gene            complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ865_001678"
     CDS             complement(11184..13343)
                     /gene="nrdE"
                     /locus_tag="VQ865_001678"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000523276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HET3135989.1"
                     /translation="MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVV
                     PNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLEELAQFIKDQNFQFKSFMAAYKF
                     YNQYALKTNDGEYYLENMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN
                     AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVR
                     VKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYGVPFNYIDITEKYDELVANPNI
                     RKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPS
                     LINDAQEFLQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPT
                     IDHGNSQAHTFGLGAMGLHSYLAQQLIEYGSPESVEFTSIYFMLMNYWTLVESNNIAR
                     ERGITFHNFEKSDYANGSYFDKYVTGEFVPTSDRVKELFKNVFIPGVADWAELRDKVQ
                     EDGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETI
                     PYYTSAYDMDMRKVIDVYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLS
                     ILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI"
     gene            complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ865_001679"
     CDS             complement(13424..13642)
                     /gene="nrdH"
                     /locus_tag="VQ865_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HET3135990.1"
                     /translation="MVTVYSKNNCVQCKMTKRFLDSNNVSYREINLDEQPEYVDQVKE
                     LGFSAAPVIQTPTEVFSGFQPGKLKQLA"
     gene            13993..14256
                     /locus_tag="VQ865_001680"
     CDS             13993..14256
                     /locus_tag="VQ865_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019775469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HET3135991.1"
                     /translation="MASKDFHVVAETGIHARPATLLVQTASKFASDITLEYKGKSVNL
                     KSIMGVMSLGVGQGADVTISAEGADADDAIAAISETMEKEGLA"
     gene            14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ865_001681"
     CDS             14262..15995
                     /gene="ptsP"
                     /locus_tag="VQ865_001681"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HET3135992.1"
                     /translation="MTEMLKGIAASDGVAVAKAYLLVQPDLSFETITVEDTNAEEARL
                     DAALQASQDELSVIREKAVGTLGEEAAQVFDAHLMVLADPEMISQIKETIRAKKVNAE
                     AGLKEVTDMFITIFEGMEDNPYMQERAADIRDVTKRVLANLLGKKLPNPASINEEVIV
                     IAHDLTPSDTAQLDKNFVKAFVTNIGGRTSHSAIMARTLEIAAVLGTNNITEIVKDGD
                     ILAVNGITGEVIINPTDEQAAEFKAAGEAYAKQKAEWALLKDAQTVTADGKHFELAAN
                     IGTPKDVEGVNNNGAEAVGLYRTEFLYMDSQDFPTEDEQYEAYKAVLEGMNGKPVVVR
                     TMDIGGDKELPYFDMPHEMNPFLGFRALRISISETGDAMFRTQIRALLRASVHGQLRI
                     MFPMVALLKEFRAAKAVFDEEKANLLAEGVAVADNIQVGIMIEIPAAAMLADQFAKEV
                     DFFSIGTNDLIQYTMAADRMNEQVSYLYQPYNPSILRLINNVIKAAHAEGKWAGMCGE
                     MAGDQQAVPLLVGMGLDEFSMSATSVLRTRSLMKKLDTAKMEEYANRALTECSTMEEV
                     LELQKEYVNFD"
     gene            16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ865_001682"
     CDS             16250..>16933
                     /gene="phtA"
                     /locus_tag="VQ865_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3135993.1"
                     /translation="MKINKKYLVGSAAALILSVCSYELGLYQARTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIFSEE
                     LLMKDPNYKLKDEDIVNEVKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT         5282 a         3057 c         3509 g         5085 t
ORIGIN      
        1 tccacgtaaa tccagcaaac tcaagccgct aatagctgaa gataaagcct ataaccatgc
       61 gctatctaag gatagaagca aggttgagaa catctttgcc aaagtaaaaa cgtttaaaat
      121 gttttcaaca acctatcgaa atcatcgtaa acgcttcgga ttacgaatga atttgagtgc
      181 tggtattatc aatcatgaac taggattcta gttttgcagg aagtctaata aagaaactag
      241 caaggtcagg ccttacttta ttggtggaca tccaggattt aattgtcttc tacttgatga
      301 tgaagtctat gaagattatt atctagagtt tgagaaagaa gagatttgct ctgttccacg
      361 tcctttccca gaaacaggta tgttggattt ccaagataga agtccatggc tagagggaca
      421 aaaagaaata gatcttagtt atgatctttt cagcacagat gcagtgactt tggatgaatt
      481 gcaatctcga acaattgccc ttcgttctct taaacatgat aagggattga aagtgcattt
      541 tgcagaattt ccaaacctca tcatctggtc aactttgaac aagggacctt tcattacctt
      601 tgaaccatgg tctggcttgt caacattcct tgaagaagga gatcatttag aagataagaa
      661 gaatgtttgt ctcttagaag ccaatcaggt tgaagaatta gggtttgaga tagaagtttt
      721 ataaaaaaag taaaaaataa ataacaaaaa caaacacaaa ctgttgactt cttcaaacaa
      781 tagtagtata ttatgtttgt gaggactaat tgactgtttt ttaaagacag ccaatacact
      841 gctggaatcc agcatagaaa aaataaaaag gagtatacaa tatgtctatt gttatcggtg
      901 cagatgctgc aggtttgaga ttgaaagaag ttgtgaaaga cttcttagaa aaagaaaact
      961 tccaccttgt ggatgttaca gctgaaggtc aagactttgt tgatgtgact ctcgctgttg
     1021 ctgcagaagt aaacaaagaa gaacaaaacc ttggtatcgt gattgatgct tatggagctg
     1081 gtccatttat ggttgcaact aagatcaaag gaatggttgc tgcagaagta tctgacgaac
     1141 gttcagctta tatgactcgt ggccacaaca actcacgtat gatcactatg ggggcacaac
     1201 ttgttggtga tgaattggct aaaaacatcg ctaaaggatt tgttaatggt aaatacgacg
     1261 gtggtcgtca ccaaatccgg gttgacatgt tgaacaaaat gtgctaatta gattatagta
     1321 agaaaggtaa gttaaaaatg agaattgcaa ttggatgtga ccacatcgta acagatgaaa
     1381 aaatggcggt ttcagaattt ttgaaatcaa aaggatatga agtcattgac tttggtacct
     1441 atgaccatac acgtactcac tacccaatct ttggtaaaaa agtaggggaa gcagtaacta
     1501 gtggtcaagc tgatctcggg gtatgtatct gtggtactgg tgttggtatc aacaacgctg
     1561 taaataaagt tccaggtgtt cgttctgcct tggttcgtga tatgacaaca gccctttatg
     1621 ctaaagaaca attgaacgcc aacgttatcg gttttggtgg taagattact ggtgaattgc
     1681 ttatgtgtga tatcatcgaa gctttcattc atgctgaata caaaccatct gaagaaaaca
     1741 aaaaattgat tgcgaaaatt gaacaccttg aaagtcacaa tgctcaacaa acagacgcaa
     1801 acttcttcac tgaattcctt gaaaaatggg atcgtggaga ataccacgac taagaggtaa
     1861 cctatgattt taacagttac aatgaaccca tccattgata tttcctatcc cttggatgag
     1921 ttgaagattg atactgtcaa tcgtgtggtg gatgtaacca aaacggctgg tggtaaggga
     1981 ctcaatgtta cccgagtact ttcagaattt ggcgattctg ttcttgctac tggtttagtg
     2041 ggtggcaaac ttggtgagtt tttggttgaa catatcgata atcaagtaaa gaaagatttc
     2101 ttctcaattc agggagaaac tcgtaactgt atcgctattc tccacggaga caaccaaaca
     2161 gaagttcttg aaaaaggtcc tgaagtattg gaacaggaag gtcaagactt tttggaacat
     2221 ttcaaaaaac tcttggagtc agttgaagta gtggccatct caggtagtct gccagctggc
     2281 cttccagttg attactgtgc gagcttggta gaacttgcta atcaagctgg caagcctgta
     2341 gtcttggact gctcaggtgc agcacttcag gctgttcttg aatcacccca taaaccaaca
     2401 gtcatcaaac caaataatga agaattgtct cagcttcttg gaagagaagt ttctgaggat
     2461 ttggatgaat taaaagaagt acttcaagaa cctttgtttg cagggattga atggattatc
     2521 gtttcacttg gtgccaacgg tacttttacc aaacatggtg acactttcta caaggtagat
     2581 attcctagaa ttcaggcggt aaatcctgtt ggatctggag actctactgt ggcaggaatt
     2641 tcttcaggac ttcttcacaa agaatcggat gcagaattac tcatcaaggc aaatgtcctt
     2701 ggtatgctca atgctcaaga aaaaatgact ggtcatgtca acatggccaa ctatcaagct
     2761 ctatatgatc aattaatagt aaaagaggta taaaatggct ttaacagaac aaaaacgtgt
     2821 acgcttagaa aaactttctg atgaaaatgg tatcatctca gctcttgcat ttgaccaacg
     2881 tggtgctttg aaacgcctca tggctcaaca ccaaacagaa gaaccaactg tggcccaaat
     2941 ggaagaactt aaagttttgg tagcagatga attgactaaa tacgcttcat ctatgcttct
     3001 tgaccctgag tatggacttc cagcaactaa agctcttgat gaaaaagctg gtcttctcct
     3061 tgcttatgaa aaaacaggtt atgacacaac aagcacaaaa cgcttgccag actgcttgga
     3121 tgtttggtct gcaaaacgta ttaaagaaga aggtgcagat gcagttaaat tcttgcttta
     3181 ctatgatgta gatagctcag acgaactcaa tcaagaaaaa caagcctaca tcgaacgcat
     3241 cggttctgag tgtgtggctg aagatatccc attcttcctt gaaatccttg cttacgatga
     3301 aaaaattgca gacgcaggtt ctgtagaata cgctaaagta aaaccacaca aagttatcgg
     3361 tgctatgaaa gtcttttcag acccacgctt taacattgat gtcttgaaag ttgaagttcc
     3421 tgttaacatt aaatatgttg aaggcttcgc tgagggtgaa gtggtttaca cacgtgaaga
     3481 agcagcagcc ttcttcaaag cgcaagatga agcaacgaac ttgccataca tctacttgag
     3541 tgctggtgta tcagctaaac tcttccaaga tactcttgta tttgctcatg aatcaggtgc
     3601 aaactttaac ggagttcttt gtggccgtgc tacatgggca gggtcagttg aagcttacat
     3661 caaagatggt gaagcagcag ctcgcgaatg gcttcgcaca actggatttg aaaacattga
     3721 tgagctcaat aaagttcttc aaacaacagc gacttcatgg aaagaacgtg tgtaagaaag
     3781 tcctcctagt ttaggaacat gaatctaaaa aaatttaaaa aaagttgtat gtaaaggttt
     3841 acaaaataac ttacttgtgc tatacttaaa tcacaagtta atacaaggtg agtgttacta
     3901 agtaatatta ggcatgatca caggtgaatt agaaatcagc tgattttcta gttcatttgt
     3961 ggtcattttt tgtactcata tacctttaaa atataaaagg aggttgacat gtatcgaatt
     4021 ctaaatccaa tgaatcacaa tgtctcgctt gtcagaaatg ataagggaga agaggtgatt
     4081 gtaattggta aggggattgc attcggaaag aagaaggggg atttgattgc tgaaaatcag
     4141 gttgagaaaa tctttcggat gaagaccgaa gagtccagag aaaactttat ggctcttctc
     4201 aaagatgttc cgcttgattt tatcacagtg acctatgaaa ttattgataa gctatcaaag
     4261 aaatatcatt atccgattca agagtatctc tatgtaacct tgacagatca tatttactgt
     4321 tcttatcaag ctctaactca aggaaggtac aaggatagta atctgccaga tatttccgct
     4381 aagtatcctg tcgcttttca aatcgcaaat gaagcttttg aaatttaccg tcagaagcta
     4441 gcagatcatt ttcctgagga cgaaattatt cggattgctt atcatttcat taatgctgaa
     4501 ggtgaaaatg aagtggaact tgtggagtcg attgataaga ggaaagaaat tctcaggaat
     4561 gttgaagaag ttttaacgga ctatgcaatt caacgaacta aaaagaataa ccatttctat
     4621 gatcgcttta tgatccattt gaattatttc ttggattatt tagacagatc tagagatgat
     4681 aaccaatcac ttctggatat ggaagatcat attaaacaat cctatccaaa agccttcgag
     4741 attggttcca agatctatga tgtgattacg caacatacgg gtcttgattt gtataaaagt
     4801 gaacgagttt atctagttct acatatccaa cgtttattgt cataaaaatt tatttaaaac
     4861 tatataagga gaattctatc atgaatagag aagaagtaac attgttaggt tttgaaatcg
     4921 tagcctatgc tggcgatgct cgttcaaaac tattggaagc cttgaaggct gctgaagctg
     4981 gtgattttga aaaagcggac gctctggtag aggaagctgg tagctgtatt gcagaggctc
     5041 accacgcgca aacaagtcta ttgactaagg aagcttctgg tgaggactta gcgtatagtg
     5101 tgaccatgat gcatggtcaa gatcacttga tgacaactat cttgttaaaa gacctaatgc
     5161 accatttaat tgaactttac aagagaggag ttaaataatg aataaactaa ttgcatttat
     5221 cgagaaagga aagcctttct ttgaaaaact atctcgtaat atctatcttc gtgctattcg
     5281 tgatggtttc attgcaggta tgcctgttat tctcttctca agtatcttta tcttgattgc
     5341 ctttgtacca aactcatggg gctttaaatg gtctgatgaa gttgtagcct ttctgatgaa
     5401 accttatagc tattctatgg gtattctggc tctcttggta gctggtacaa cagctaagtc
     5461 attgactgac tcagtaaacc ggagcatgga aaaaaccaat caaatcaact atatgtcaac
     5521 attgttggca gcaattgttg gtttgttgat gttggcagct gatcctatcg aaagtggtct
     5581 agctactgga ttcttgggaa caaaaggttt gctttcagcc ttccttgctg ccttcgttac
     5641 tgtagccatc tataaggtct gtgttaagaa caacgtcact attcgtatgc ctgacgaagt
     5701 tccaccaaat atctcacaag tctttaaaga tgtgattcca ttcactctat cagtggtttc
     5761 tctttatgct cttgatttac tagctcgtca ttttgttggt tctagtgtgg cagaatcaat
     5821 cggtaaattc ttcgcaccac tcttctcagc agcagacgga taccttggta ttaccattat
     5881 ctttggtgcc tttgccttct tctggtttgt tgggattcat ggtccatcta tcgttgaacc
     5941 tgctatcgca gcgattacct atgcaaatgc tgaagtcaac ttgaaccttc tccaacaagg
     6001 gatgcatgca gacaagattc ttacttctgg tacacaaatg tttatcgtta ccatgggtgg
     6061 tacaggtgcg acattggtcg ttccatttat gttcatgtgg ttgacaaaat cgaaacgtaa
     6121 ccgtgcaatc ggacgtgctt cagtagttcc taccttcttc ggtgtaaatg aaccaatctt
     6181 gtttggtgca cctcttgttt tgaatccaat cttcttcatt ccatttatct ttgctccaat
     6241 tgcaaacgta tggattttca aattctttat tgaaactctt ggaatgaact cattcactgc
     6301 taatctacca tggacaactc cagctccact aggtctagtt cttggaacta acttccaagt
     6361 gctatcattc attcttgctg cccttctaat tgtggttgac gtagttattt attacccatt
     6421 ccttaaagtc tatgatgaac aaattcttga agaagaacgt tcaggtaagt ctaatgatga
     6481 attgaaagaa aaagttgctg caaacttcaa cactgcaaaa gcggatgcta ttcttgaaaa
     6541 agcgggtgtc gatgcagcac aaaataccat cactgaagaa acaaatgtcc tcgttctctg
     6601 tgctggtgga ggtacaagtg gactccttgc aaatgctttg aataaggcag cagcagaata
     6661 caatgtccct gtgaaagcag cagcaggcgg ctatggtgct caccgtgaaa tgttgccaga
     6721 gtttgatttg gttatccttg ctcctcaagt tgcttcaaac tttgaagata tgaaggcaga
     6781 aacagataag ctcggtatta aacttgctaa gacagaaggc gctcaataca tcaaattaac
     6841 tcgtgatgga aaaggtgccc tagcattcgt acaagagcaa ttcgattaag gctaggaact
     6901 gtgaaacagt ctcccatcgt tacggaaatc gctatggcga atttcctaat cgccttatta
     6961 attcgtcggt aaaaagatat cgtttttacc tcctcatgtc acaattcagt gacttggtac
     7021 aagaagtgag atggagaagc atggctcact gactcctctc ctctcacttt tactttattt
     7081 aaatcaagaa ataggtgaaa aaaatgacaa aaacacttcc aaaagacttt attttcggtg
     7141 gcgcaacagc tgcttatcaa gcagaaggtg ctacacatac tgatggaaaa ggaccagttg
     7201 cttgggataa atatcttgag gataactact ggtacactgc cgaaccagct agtgattttt
     7261 acaatcgata tccagttgac ctcaagctag cagaagagta tggtgtcaat ggtattcgaa
     7321 tttctattgc ctggtcacgt attttcccga ctggttacgg ccaagtaaat gttaaaggtg
     7381 ttgagtttta tcataattta tttgcagagt gtcacaaacg tcatgttgag ccctttgtaa
     7441 ctcttcatca ctttgacacg ccagaagctc tccattcaaa tggagacttc ttaaaccgtg
     7501 aaaatatcga acattttgta gactacgctg ccttctgttt tgaagaattt ccagaagtaa
     7561 actattggac aacctttaat gaaattggac caatcggtga tggtcaatat ttggttggga
     7621 aattccctcc aggtatccag tacgaccttg ccaaagtctt tcaatcacac cacaatatga
     7681 tggtgtctca tgcgcgtgca gtcaagctat ataaagataa aggctataaa ggggaaattg
     7741 gtgttgttca cgctctgcca accaagtatc ctttggatcc taaaaatcca gcagatgttc
     7801 gtgcagctga gttggaagat atcatccaca ataaattcat cttagacgca acttatctag
     7861 gtcgctattc agctgaaacc atggaaggtg tcaaccatat cttatcagtc aatggtggta
     7921 gtttggatct tcgtgaagaa gattttacaa cattagaagc tgcaaaagac ttgaatgatt
     7981 tcctaggaat caactactat atgagtgact ggatggaagc ctttgatgga gaaactgaaa
     8041 ttatccataa tggtaaaggt gaaaaaggaa gctctaagta tcaaatcaaa ggtgttggtc
     8101 gtcgtgtagc tcctgactat gtaccacgca cggattggga ttggattatc taccctcaag
     8161 gtttgtatga ccaaatcata cgtgtgaaga aagattatcc taactacaag aagatttaca
     8221 tcactgaaaa tggtctcggc tataaagatg agttcgttga taacactgtt tacgatgatg
     8281 gtcgtattga ttacgtgaaa caacacttgg agatcttgtc tgatgcgatt gcagatggag
     8341 ctaatgtaaa aggttacttc atttggtcat taatggatgt cttctcatgg tcaaacggtt
     8401 atgaaaaacg ttacggtctc ttctacgtag attttgaaac tcaagaacgt tatcctaaga
     8461 aatcagctca ctggtataag aaagtagcgg aaactcagat tatagactag tagaattagt
     8521 cattagatat agaattttag tgagtcaaaa agatgttcaa agattttatc caatctattt
     8581 atgaaaaaaa gtttatatta taaatttcga aaaatgctct caaataccgt gtttgacgag
     8641 tgaagaattg aaaagtcttg gaaaatggta tgtctcgact ggtaaagaat ggatttgtca
     8701 ttcagatgat gagctggaag aatttaaaaa tctattttta aattttatca atcctgaaga
     8761 atgggatact atctcctttg attcagattt tatgccgttt caacaatcgt aaccaatttc
     8821 tcaaaaaagt taaatcttat atttagtact ctgtaaaact cttatctaat cacgttgctt
     8881 atactcaatg aaaatcaaag agcaacttta aactaggaag cgagtcgcag atttctcaat
     8941 gcatagcttt gaggaattgg gcaaaaagtc tttgatatag aaaaacgcat agtatcaggt
     9001 gtttcaacac ctgatattat gcgttttatt gtgggaagat ttactttttt tcttctgaaa
     9061 ttgagttgtt acccaggctc tttcagttta ttaaggcttg atgactttaa tgtgtttaga
     9121 tagcttaaaa aggattgaat cacttagttt agaatctgaa acaatagtat caagatttga
     9181 tacattataa aaagtataaa aatcaaactt attgaacttg ctatgatctg cgagtaaata
     9241 ttttttatta gaattattta aagcgatgcg ttgagcctct ccctcttcct cgctaaaagt
     9301 agctagagct ccgttttgaa taccattaca gctaacgaaa gctttagaaa attggagatt
     9361 agagagattt tgtagggtca atgtaccaac aaaagcacct gtaatatcgc gataatttcc
     9421 acctattaaa atcaaatctg ttaattttcg ttcgcttaaa atcagaaaaa caggtagact
     9481 gttggttacg acgcggatat tgtcaatagg caactcacgc gcaaaaaact ctaatgttgt
     9541 tcctggtcca atgaaaatag tttctctttc ttctactaga ctgcctgcaa aatgggctat
     9601 ttcttgtttt tctgccgttt ggagggcttg tttttcaata tttgatcgct cattagtcaa
     9661 aagggagttg gttcgaagtt tttcagctcc accatgcaca cgaatcagca aatctttatc
     9721 agctaattcc tgtaaatagc gccttgcagt catatctgaa acggctattt cgtccataat
     9781 ctgtttaact gttatggttc ctttactatt tactatctct aaaattttgg ttaatttttc
     9841 ttgtttgagc atattatcac ctcgtttcct actactatct taccataaac aaactcatca
     9901 ttcaaataca aaaacaacaa aatgaaacaa aaacaaaaat atcgaagttt gttttcaaaa
     9961 ctttcgatat ttttgttggg ttataacttt gatgtttcta gtttactttt tgatgattga
    10021 gagtgatgga gaattagtct aaaccgtagt tatagtcatc gtcttgcatg gcttcaactt
    10081 cgccaagaag gtaaccattt ccgacttgag agaagaagtc atggttggaa gttcctgttg
    10141 aaataccgtt cataacgatt gggttgacat cttcagctga atctgggaaa agtggatctt
    10201 gtcccatgtt catgagagct ttattggcat tgtagcgaag gaaggtttta acctcttcag
    10261 tccaaccaac accgtcataa agactctctg tgtagccttc ttcattttca taaagagtat
    10321 agagtaggtc gtacatccat tctttgagtt tttcttgctc ttcttcaggc aattcattga
    10381 aaccaagttg gaatttgtaa ccaatgtagg ttccgtgaac agactcgtca cgaataatca
    10441 atttaatgat ttctgcaacg ttggctagtt tgttgttacc gagatagtag aggggagtga
    10501 agaaaccaga gtagaagagg aaggtttcga ggaagacgct ggcaactttc ttttcaagtg
    10561 ggctgccgtt taggtagatt tcgttgacaa tctcagcctt cttttgtagg taaggattgg
    10621 tattggtcca ttcgaaaatt tcttcaatct cagccttagt attcaaggta gaaaagattg
    10681 atgagtaaga tttagcgtgg acagattcca taaattggat gttattgaaa acagcttcct
    10741 catgtggtgt acggatgtct gcgcgaaggg cttgaacccc agtttcagat tgcatagtgt
    10801 caagaagggt taaaccacca aaaacttttc cgaccaagtc tttctctttg ttagatagct
    10861 ttctccagtc atccaagtcg tttgataagg gaatacgtgt atcgagccaa aattgctccg
    10921 tcagtttttc ccaagttgat ttgtcgatga catcttcgat ggcattccag ttaatggctt
    10981 tgtagtaagt ttccatttaa aatctctttc tgtgtttagt attgcgaact cacaattatt
    11041 tctactttac cataattcta taggagtatc gcacaaaaag tcggaagccc gacttttaaa
    11101 atgttacata aattatgtta tgacatagta gatttgattt tatcagtgct gcttagggaa
    11161 aaataatgtt tctatgctag aaactaaatc acacagcttt cacattggtt ggcgccgact
    11221 tctccaccgt catctgtaaa ggtacggacg tagtagatag acttgattcc cttgttaaag
    11281 gcatagttac gaaggatgga caaatcacgt gtcgtttgtt tattttccct cttccattcg
    11341 taaaggcctt ttggaatgtc actgcgcatg aagagggtga gtgaaagtcc ttgatccacg
    11401 tgttcagtcg cagcagcgta aacatcgatg actttacgca tatccatatc gtaggcagaa
    11461 gtgtagtaag gaatggtttc tgtagacaag ccagcagcag ggtagtagat tttaccaatt
    11521 ttcttctctt ggcgttcttc gatacgttgc gtaatcgggt ggatagaagc agaaacgtcg
    11581 ttgatatagc tgatagaacc atttggcgct acagcaaggc gattttggtg gtaaagacca
    11641 tcttcttgaa ccttgtcgcg aagttcagcc caatcagcaa caccagggat aaaaacattt
    11701 ttgaagagtt ctttaacacg gtctgatgtt ggaacaaatt caccagttac atacttgtca
    11761 aagtaacttc cgttagcata gtctgatttt tcaaagttgt ggaaggtaat accacgttca
    11821 cgcgcaatat tgtttgactc taccaaggtc cagtagttca taagcataaa gtagatgctt
    11881 gtaaattcaa cagactcagg tgaaccatat tcaatgagtt gttgggcaag gtagctgtgc
    11941 agtcccatgg caccgagacc aaaggtgtgg gcttggctat ttccatggtc aatcgttggt
    12001 acagctacga tatgtgaact atctgtaacg aaagtaaggg cacgaaccat agcacggata
    12061 gaacgaccaa aatcaggtga agtcatcatg ttaaccacgt tggttgaacc cagattacat
    12121 gaaacatctg ttcccatttg aaggaattct tgagcatcgt tgatcaagct tggttcttga
    12181 acttgaagaa tctcagaaca caagttactc atgataatct ttccatcaac aggatttgca
    12241 cggttagccg tatcgatgtt gactacataa ggatagccag actcttgttg caatttagag
    12301 atttcagttt ccaaatcccg cgccttgatt tttgtcttgc gaatatttgg atttgcgacc
    12361 aattcatcgt atttttcagt aatgtcgatg taattgaatg gcacaccgta ttctttttct
    12421 acagagtaag ggctgaagag gtacatttct tcatttttac gagccaattc gtagaattta
    12481 tcaggtacta caacaccaag tgatagagtc ttgacacgta ctttttcatc agcgttttct
    12541 ttcttagttg aaaggaaagc gatgatatct gggtgaaaga cgttgaggta gacaacacca
    12601 gcaccttgac gttgccccaa ttggttggag taagagaagc tgtcttcaaa aagcttcata
    12661 acaggaacga cacctgaagc agctccttca tagcctttga taggtgcacc agcttcacga
    12721 aggttgctga gggtaattcc cacaccacca ccaatacgtg aaagttgaag agctgagttg
    12781 atagaacgtc cgatagagtt catatcatcc gtcacttgga ttaggaaaca agataccaac
    12841 tccccacgac gagcacgtcc agcattcaag aaggaaggag tagcaggttg gtagcgttgg
    12901 tggatgattt cattggcaat atcgattgca acagcttcat tcccatcagc gaaataaagg
    12961 gcgttgaaga agacacggtc ttccatattt tcaagatagt attcaccgtc attagtcttt
    13021 aaggcatatt gattgtaaaa tttataagct gccatgaatg acttgaattg gaagttttgg
    13081 tctttgataa attgagccaa ttcttccaag aactctggac ggtatttctt gataaaggct
    13141 gtttcgatgt agttgtgttc aatgaggtaa ttgattttgt ctttgattga atcaaaaacc
    13201 atagtgtttg gaactacatt ttctttaaag aaagcatcca aggcttcctt atctttatga
    13261 agcatgattt gtccattaac aggacggtta atttcgttat taagacggaa gtaagtcacg
    13321 tcttcaagat gttttaatcc cataaaattt cccttatcta attacaaaag aaaggcttct
    13381 aagttagccc taaaagcagt ttcttctgga tgatgtacta agattatgct aattgtttca
    13441 gttttcctgg ttggaaacct gaaaagactt cagttggtgt ttggataaca ggagctgcgc
    13501 taaaaccgag ctctttaact tgatcgacgt actcaggttg ctcatcaaga ttgatttcac
    13561 gataagagac attattactg tccaagaaac gcttggtcat tttacattgg acacaattgt
    13621 ttttagaata aacggttacc attgtgtaac tcctcttcaa aatttaatac tatcttagta
    13681 tatcagaaaa taaaattttg tcaatgattt gaactaaata tagtggtgtt cttttgttgt
    13741 ttttatatat aaacacaata tatagtgttt gtattgtgaa atagcaatga ttatcctata
    13801 aattgttttt aaagaaacta tatcctgtgt tttgttatct aggatagaag attttcagca
    13861 agttatctga aaggaaattg aaggaaaatc cagaaaatgc ttgaaaaaaa tcctagaaga
    13921 tggtataata ctaaattgta agggttatca catataactc aaaaaaagaa agaacaaaag
    13981 gagagtcaaa ctatggcttc taaagatttc cacgtagtgg cagaaacagg tattcacgca
    14041 cgtccagcaa cattgttggt acaaactgct agcaaatttg cttcagatat cactcttgag
    14101 tacaaaggta aatcagttaa ccttaaatca attatgggtg ttatgagtct tggtgttggt
    14161 caaggtgctg acgtaactat ctcagctgaa ggtgcagatg cagatgacgc tatcgctgca
    14221 atctcagaaa caatggaaaa agaaggattg gcataaggga aatgacagaa atgcttaaag
    14281 gaatcgcagc atctgacggt gttgcagttg caaaagcata tctactcgtt cagccggatt
    14341 tgtcatttga gactattaca gtcgaagata caaacgcaga agaagctcgc cttgatgccg
    14401 ctctacaggc atcacaagac gagctttctg ttattcgcga gaaagcagta ggtacgctcg
    14461 gtgaagaagc agctcaagtt tttgatgctc acttaatggt tcttgctgac ccagaaatga
    14521 tcagccaaat caaggaaact atccgtgcga agaaagtgaa tgcagaagca ggtctgaaag
    14581 aagttacaga tatgtttatc actatctttg aaggcatgga agacaaccca tacatgcaag
    14641 aacgcgcagc ggatatccgc gacgtgacaa aacgtgtatt ggcaaacctt cttggtaaaa
    14701 aattgccaaa cccagcttct atcaatgaag aagtgattgt gattgcgcat gacttgactc
    14761 cttcagatac agctcaattg gacaaaaact ttgtaaaagc ttttgtaacc aacattggtg
    14821 gacgtacaag ccactcagct atcatggcac gtacacttga aattgctgct gtattaggta
    14881 caaacaacat cactgaaatc gttaaagacg gtgacatcct tgctgttaac gggatcactg
    14941 gagaagtgat tatcaaccca acagatgaac aagcggcaga atttaaagca gctggtgaag
    15001 cctatgcgaa acaaaaagct gaatgggcac ttttgaaaga tgctcaaaca gtgactgctg
    15061 acggtaaaca cttcgagttg gctgccaata ttggtactcc aaaagacgtt gaaggtgtta
    15121 acaacaacgg tgcagaagct gttggacttt accgtacaga gttcttgtac atggattctc
    15181 aagacttccc aactgaagat gagcagtatg aagcatacaa ggctgttctt gaaggaatga
    15241 acggtaaacc tgttgtcgtt cgtacaatgg atatcggtgg agataaggaa cttccttact
    15301 tcgatatgcc tcacgaaatg aacccattcc ttggattccg tgctcttcgt atctctatct
    15361 ctgagactgg agatgctatg ttccgcacac aaatccgtgc tcttcttcgt gcgtctgttc
    15421 acggtcaatt gcgtatcatg ttcccaatgg ttgcgctctt gaaagaattc cgtgcagcga
    15481 aagcagtctt tgatgaagaa aaagcaaacc ttcttgctga aggtgttgca gttgcggata
    15541 acattcaagt tggtatcatg atcgagattc ctgcagcggc tatgcttgca gaccaatttg
    15601 ctaaagaagt tgacttcttc tcaattggta caaatgactt gatccaatat acaatggcag
    15661 cagaccgtat gaacgaacaa gtttcatacc tttaccaacc atacaaccca tcaatcctac
    15721 gcttgattaa caatgtgatc aaagcagctc acgctgaagg taaatgggct ggtatgtgtg
    15781 gtgagatggc tggtgaccaa caagctgttc cacttcttgt cggaatgggc ttggatgagt
    15841 tctctatgtc agcaacatct gtacttcgta cacgcagctt gatgaagaaa ctcgacacag
    15901 ctaagatgga agagtacgca aaccgtgccc ttacagaatg ctcaacaatg gaagaagttc
    15961 ttgaacttca aaaagaatac gttaattttg attaatcgaa aagtccctgc aactcagtta
    16021 cagggacttt ttttgatatt ttaaaaagaa ttttcaagaa aatctttctt ataaaaagtc
    16081 caaccttgaa aaagtagtgg tcagaacaaa aaatacttaa atggttcata aaattcttga
    16141 caagttggag atttaggagt aaactattaa ccagttaagt aatagagagg agtttctgca
    16201 atttagaaat gaattgcaac tagaaatatc aaatagaaag agagtttcga tgaaaattaa
    16261 taagaaatac cttgttggtt ctgcggcagc tttgatttta agtgtttgtt cttacgagtt
    16321 gggactgtat caagctagaa cggttaagga aaataatcgt gtttcctata tagatggaaa
    16381 acaagcgacg caaaaaacgg agaatttgac tcctgatgag gttagcaagc gtgaaggaat
    16441 caatgctgag caaatcgtca tcaagataac agaccaaggc tatgtcactt cacatggcga
    16501 ccactatcat tattacaatg gtaaggttcc ttatgatgcg attttcagtg aagaattact
    16561 catgaaagat ccaaactata agctaaaaga tgaggatatt gttaatgagg tcaagggtgg
    16621 atatgttatc aaggtagatg gaaaatacta tgtttacctt aaggatgctg cccacgcgga
    16681 taacgtccgt acaaaagagg aaatcaatcg acaaaaacaa gaacatagtc aacatcgtga
    16741 aggtgggact ccaagaaacg atggtgctgt tgccttggca cgttcgcaag gacgctatac
    16801 tacagatgat ggttatatct ttaatgcttc tgatatcata gaggatactg gtgatgctta
    16861 tatcgttcct catggagatc attaccatta cattcctaag aatgagttat cagctagcga
    16921 gttggctgct gca
//
LOCUS       DAVBOG010000046        16445 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.046, whole genome shotgun sequence.
ACCESSION   DAVBOG010000046 DAVBOG010000000
VERSION     DAVBOG010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 16445)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16445)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16445
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.046"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..906
                     /gene="lytB"
                     /locus_tag="VQ865_001683"
     CDS             <1..906
                     /gene="lytB"
                     /locus_tag="VQ865_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010976495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endo-beta-N-acetylglucosaminidase"
                     /protein_id="HET3135994.1"
                     /translation="YMAKNETVDGYQLGSDGKWLGGKATNENAAYYQVVPVTANVYDS
                     DGEKLSYISQGSVVWLDKDRKSDDKRLAITISGLSGYMKTEDLQALDASKDFIPYYES
                     DGHRFYHYVAQNASIPVASHLSDMEVGKKYYSADGLHFDGFKLENPFLFKDLTEATNY
                     SAEELDKVFSLLNINNSLLENKGATFKEAEEHYHINALYLLAHSALESNWGRSKIAKD
                     KNNFFGITAYDTTPYLSAKTFDDVDKGILGATKWIKENYIDRGRTFLGNKASGMNVEY
                     ASDPYWGEKIASVMMKINEKLGGKD"
     gene            complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ865_001684"
     CDS             complement(967..2622)
                     /gene="pavA"
                     /locus_tag="VQ865_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_094859469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rqc2 family fibronectin-binding protein PavA"
                     /protein_id="HET3135995.1"
                     /translation="MSFDGFFLHHIVEELRSELVNGRIQKINQPFEQELVLQIRSNRQ
                     SHRLLLSAHPVFGRIQLTQTTFENPAQPSTFIMVLRKYLQGALIESIEQVENDRIVEI
                     TVSNKNEIGDHIQATLIIEIMGKHSNILLVDKSSHKILEVIKHVGFSQNSYRTLLPGS
                     TYIAPPSTKSLNPFTIKDEKLFEILQTQELTAKNLQSLFQGLGRDTANELERILVSEK
                     LSAFRNFFNQETKPCLTETSFSPVPFANQVGEPLANLSDLLDTYYKDKAERDRVKQQA
                     SELIRRVENELQKNRHKLKKQEKELLATDNAEEFRQKGELLTTFLHQVPNDQDQVILD
                     NYYTNQPIMIALDKALTPNQNAQRYFKRYQKLKEAVKYLTDLIEETKATILYLESVET
                     VLNQAGLEEIAEIREELIQTGFIRRRQREKIQKRKKLEQYLASDGKTIIYVGRNNLQN
                     EELTFKMARKEELWFHAKDIPGSHVVISGNLDPSDAVKTDAAELAAYFSQGRLSNLVQ
                     VDMIEVKKLNKPTGGKPGFVTYTGQKTLRVTPDSKKIASMKKS"
     gene            2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ865_001685"
     CDS             2727..3224
                     /gene="ybeY"
                     /locus_tag="VQ865_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018380869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HET3135996.1"
                     /translation="MYIEMVDETGQVSKEMLQQTQEILEFAAQKLGKEDKEMAVTFVT
                     NERSHELNLEYRDTDRPTDVISLEYKPELEIAFDEEDLLENPELAEMMSEFDAYIGEL
                     FISIDKAHEQAEEYGHSFEREMGFLAVHGFLHINGYDHYTPEEEAEMFGLQEEILTAY
                     GLTRQ"
     gene            3205..3600
                     /locus_tag="VQ865_001686"
     CDS             3205..3600
                     /locus_tag="VQ865_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000378166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HET3135997.1"
                     /translation="MDSQDNKRKWKNRDLISSLEFALTGIFTAIKEERNMRKHAVTAL
                     VVILAGFVFQVSRIEWLFLLLSIFLVVAFEIINSAIENVVDLASHYHFSMLAKNAKDM
                     AAGAVLVVSLFAALTGALIFLPRIWDLLF"
     gene            3617..4516
                     /gene="era"
                     /locus_tag="VQ865_001687"
     CDS             3617..4516
                     /gene="era"
                     /locus_tag="VQ865_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002935752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HET3135998.1"
                     /translation="MTFKSGFVAILGRPNVGKSTFLNHVMGQKIAIMSDKAQTTRNKI
                     MGIYTTDKEQIVFIDTPGIHKPKTALGDFMVESAYSTLREVDTVLFMVPADEARGKGD
                     DMIIERLKAAKVPVILVVNKIDKVHPDQLLSQIDDFRNQMDFKEIVPISALQGNNVSR
                     LVDILSENLDEGFQYFPSDQITDHPERFLVSEMVREKVLHLTREEIPHSVAVVVDSMK
                     RDEETDKVHIRATIMVERDSQKGIIIGKGGAMLKKIGSMARRDIELMLGDKVFLETWV
                     KVKKNWRDKKLDLADFGYNEREY"
     gene            4565..5389
                     /gene="mutM"
                     /locus_tag="VQ865_001688"
     CDS             4565..5389
                     /gene="mutM"
                     /locus_tag="VQ865_001688"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001114577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HET3135999.1"
                     /translation="MPELPEVETVCRGLEKLIIGKKISSIEIRYHKMIKTDLEEFQRE
                     LPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGG
                     TLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSH
                     LLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGS
                     TIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD"
     gene            5389..5994
                     /locus_tag="VQ865_001689"
     CDS             5389..5994
                     /locus_tag="VQ865_001689"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004259526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HET3136000.1"
                     /translation="MGKIIGITGGIASGKSTVTNFLRQQGFQAVDADAVVHQLQKPGG
                     RLFEALVQHFGQEIILENGELNRPLLASLIFSNPEEQKWSNQIQGEIIREELATLREQ
                     LAQTEEIFFMDIPLLFEQDYSDWFAETWLVYVDRDAQVERLMKRDQLSKDEAESRLAA
                     QWPLEKKKDLASQVLDNNGNQNQLLNQVHILLEGGRQDDRD"
     gene            5981..7180
                     /locus_tag="VQ865_001690"
     CDS             5981..7180
                     /locus_tag="VQ865_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter PmrA"
                     /protein_id="HET3136001.1"
                     /translation="MTEINWKDNLRIAWFGNFLTGASISLVVPFMPIFVENLGVGSQQ
                     VAFYAGLAISVSAISAALFSPIWGILADKYGRKPMMIRAGLAMTITMGGLAFVPNIYW
                     LIFLRLLNGVFAGFVPNATALIASQVPKEKSGSALGTLSTGVVAGTLTGPFIGGFIAE
                     LFGIRTVFLLVGSFLFLAAILTICFIKEDFQPVAKEKAIPTKELFTSVKYPYLLLNLF
                     LTSFVIQFSAQSIGPILALYVRDLGQTENLLFVSGLIVSSMGFSSMMSAGVMGKLGDK
                     VGNHRLLVVAQFYSVIIYLLCANASSPLQLGLYRFLFGLGTGALIPGVNALLSKMTPK
                     AGISRVFAFNQVFFYLGGVVGPMAGSAVAGQFGYHAVFYATSLCVAFSCLFNLIQFRT
                     LLKVKEI"
     gene            7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ865_001691"
     CDS             7180..7329
                     /gene="rpmG"
                     /locus_tag="VQ865_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3136002.1"
                     /translation="MRVKINLKCSSCGSINYLTSKNSKTHPDKIEVLKYCPKERKVTL
                     HLESK"
     gene            7369..7602
                     /gene="secG"
                     /locus_tag="VQ865_001692"
     CDS             7369..7602
                     /gene="secG"
                     /locus_tag="VQ865_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012000186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HET3136003.1"
                     /translation="MYNLLLTILLVLSVVIVIAIFMQPTKNQSSNVFDASSGDLFERS
                     KARGFEAVMQRLTGILVFFWLAIALALTVLSSR"
     gene            7704..10058
                     /gene="rnr"
                     /locus_tag="VQ865_001693"
     CDS             7704..10058
                     /gene="rnr"
                     /locus_tag="VQ865_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000653285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HET3136004.1"
                     /translation="MKDRIKEYLQDKGKVTVNDLAQALGKDSSKDFRELIKTLSLMER
                     KHQIRFEEDGSLKLEIKKKHEITLKGIFHAHKNGFGFVSLEGEEDDLFVGKNDVNYAI
                     AGDTVEVVIKKVADRNKGTAAEAKIIDILEHSLTTVVGQIVLDQEKPKYAGYIRSKNQ
                     KISQPIYVKKPALKLEGTEVLKVFIDKYPSKKHDFFVASVLDVVGHSTDVGIDVLEVL
                     ESMDIVSEFPEAVVKEAESVPDAPSQKDMEGRLDLRDEITFTIDGADAKDLDDAVHIK
                     ALKNGNLELGVHIADVSYYVTEGSALDKEALNRATSVYVTDRVVPMLPERLSNGICSL
                     NPQVDRLTQSAIMEIDKHGRVVNYTITQTVIKTSFRMTYSDVNDILAGDEEKRKKYHK
                     IVPSIELMAKLHETLENMRVKRGALNFDTNEAKILVDKQGKPVDIVLRQRGIAERMIE
                     SFMLMANETVAEHFSKLDLPFIYRIHEEPKAEKVQKFIDYASSFGLRIYGTASEISQE
                     ALQDIMRAVEGESYADVLSMMLLRSMQQARYSEHNYGHYGLAADYYTHFTSPIRRYPD
                     LLVHRMIRDYGRSKEIAEHFEQVIPEIATQSSNRERRAIEAEREVEAMKKAEYMEEYV
                     GEEYDAVVSSIVKFGLFVELPNTVEGLIHITNLPEFYHFNERDLTLRGEKSGITFRVG
                     QQIRIRVERADKMTGEIDFSFVPSEFDVIEKGLKQSSRSGRGRGSNRRSDKKEDKRKS
                     GRSNDKRKHSQKDKKKKGKKPFYKEVAKKGAKHGKGRGKGRRTK"
     gene            10021..10488
                     /gene="smpB"
                     /locus_tag="VQ865_001694"
     CDS             10021..10488
                     /gene="smpB"
                     /locus_tag="VQ865_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HET3136005.1"
                     /translation="MAKGEGKVVAQNKKARHDYTIVDTLEAGMVLTGTEIKSVRAARI
                     NLKDGFAQVKNGEVWLSNVHIAPYEEGNIWNQEPERRRKLLLHKRQIQKLEQETKGTG
                     MTLVPLKVYIKDGYAKLLLGLAKGKHDYDKRESIKRREQNRDIARVMKAVNQR"
     gene            10504..11364
                     /gene="tehB"
                     /locus_tag="VQ865_001695"
     CDS             10504..11364
                     /gene="tehB"
                     /locus_tag="VQ865_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000413836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent methyltransferase TehB"
                     /protein_id="HET3136006.1"
                     /translation="MEKLVAYKRMPLWNKQTMPEAVQQKHNTKVGTWGKITVLKGALK
                     FIELTEEGEVLAEHLFEAGADNPMAQPQAWHRVEAATDDVEWYLEFYCKPEDYFAKKY
                     NTNPVHSEVLEAMETVKQGKALDLGCGQGRNSLFLAQQDFDVTAVDQNGLALEILQSI
                     VEQEDLDMPVGLYDINSASIEQEYDFIVSTVVLMFLQADRIPAIIQNMQEKTSVGGYN
                     LIVCAMDTEDYPCSVNFPFTFKEGELADYYKDWELVKYNENPGHLHRRDENGNRIQLR
                     FATLLAKKIK"
     gene            11437..12390
                     /gene="coiA"
                     /locus_tag="VQ865_001696"
     CDS             11437..12390
                     /gene="coiA"
                     /locus_tag="VQ865_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000495911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HET3136007.1"
                     /translation="MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTH
                     FAHKSLKDCDFFFENESPEHLANKESLYHWLKKETKVQLEYPLSELKQIADVFVNGNL
                     ALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
                     YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTV
                     SEDKDICRYIRQQLYYQNLFWMKEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIE
                     QDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE"
     gene            12409..14211
                     /gene="pepF"
                     /locus_tag="VQ865_001697"
     CDS             12409..14211
                     /gene="pepF"
                     /locus_tag="VQ865_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004252660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HET3136008.1"
                     /translation="MVLQRNEINEKDTWDLSTIYPTDQAWEEALKDLTEQLETVAQYE
                     GHLLDSADNLLEITEFSLEMERQIEKLYVYAHMKNDQDTREAKYQEYYAKAMTLYSQL
                     DQAFSFYEPEFMEISEKQYADFLEAQPKLQVYQHYFDKLLQGKDHVLSQREEELLAGA
                     GEIFGSASETFAILDNADIVFPYVLDDDGKEVQLSHGTYTRLMESKKREVRRGAYQAL
                     YATYEQFQHTYAKTLQTNVKVQNYRAKVRNYKSARHAALAANFVPESVYDNLVAAVRK
                     HLPLLHRYLELRSKILGISDLKMYDVYTPLSSVEYSFTYQEALKKAEDALAVLGEDYL
                     SRVKRAFSERWIDVYENQGKRSGAYSGGSYDTNAFMLLNWQDNLDNLFTLVHETGHSM
                     HSSYTRETQPYVYGDYSIFLAEIASTTNENILTEKLLEEVEDDATRFAILNNFLDGFR
                     GTVFRQTQFAEFEHAIHQADQNGEVLTSDFLNKLYADLNQEYYGLSKEDNPEIQYEWA
                     RIPHFYYNYYVYQYSTGFAAASALAEKIVHGSQEDRDRYIDYLKAGKSDYPLNVMRKA
                     GVDMEKEDYLNDAFAVFERRLNEFEALVEKLGLA"
     gene            14213..14926
                     /locus_tag="VQ865_001698"
     CDS             14213..14926
                     /locus_tag="VQ865_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HET3136009.1"
                     /translation="MVESYSKNANHNMRRPVVKEEIVDLMRQRQKQVTGFLKELEDFA
                     RKENIPIIPHETVAYFRFLMETMQPKNILEIGTAIGFSALLMAEHAPNAKITTIDRNP
                     EMIGFAKENFAQFDSRKQITLLEGDAVDVLSTLTESYDFVFMDSAKSKYIVFLPEILK
                     HLEVGGVVVLDDIFQGGDVAKDIMEVRRGQRTIYRGLQKLFDATLDNPELTATLVPLG
                     DGILMLRKNVADVQLSESE"
     gene            14993..15934
                     /gene="prsA"
                     /locus_tag="VQ865_001699"
     CDS             14993..15934
                     /gene="prsA"
                     /locus_tag="VQ865_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PrsA"
                     /protein_id="HET3136010.1"
                     /translation="MKKKLLAGAITLLSVATLAACSKGSEGADLISMKGDIITEHQFY
                     EQVKNNPSAQQVLLNMTIQKVFEKQYGSELDDKEVDDTIAEEKKQYGENYQRVLSQAG
                     MTLETRKAQIRTSKLVELAVKKVAEAELTDEAYKKAFDEYTPDVTAQIIRLNNEDKAK
                     EVLEKAKAEGADFAQLAKDNSTDEKTKENGGEITFDSASTEVPEQVKKAAFALDVDGV
                     SDVITATGTQAYSSQYYIVKLTKKTEKSSNIDDYKEKLKTVILTQKQNDSTFVQSIIG
                     KELQAANIKVKDQAFQNIFTQYIGGGDSSSSSSTSNE"
     gene            complement(16051..16392)
                     /locus_tag="VQ865_001700"
                     /pseudo
     CDS             complement(16051..16392)
                     /locus_tag="VQ865_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT         4946 a         3075 c         3686 g         4738 t
ORIGIN      
        1 tacatggcga aaaatgagac agtagatggt tatcagcttg gaagcgatgg taaatggctt
       61 ggaggaaaag ctacaaatga aaatgctgct tactatcaag tagtgcctgt tacagccaat
      121 gtttatgatt cagatggtga aaagctttcc tatatatcgc aaggtagtgt cgtatggcta
      181 gataaggata gaaaaagtga tgacaagcgc ttggctatta ctatttctgg tttgtcaggc
      241 tatatgaaaa cagaagattt acaagcgcta gatgctagta aggactttat cccttattat
      301 gagagtgatg gccaccgttt ttatcactat gtggctcaga atgctagtat cccagtagct
      361 tctcatcttt ctgatatgga agtaggcaag aaatattatt cggcagatgg cctgcatttt
      421 gatggtttta agcttgagaa tcccttcctt ttcaaagatt taacagaggc tacaaactac
      481 agtgctgaag aattggataa ggtatttagt ttgctaaaca ttaacaatag ccttttggag
      541 aacaagggcg ctacttttaa ggaagccgaa gaacattacc atatcaatgc tctttatctc
      601 cttgcccata gtgccctaga aagtaactgg ggaagaagta aaattgccaa agataagaat
      661 aatttctttg gcattacagc ctatgatacg accccttacc tttctgctaa gacatttgat
      721 gatgtggata agggaatttt aggtgcaacc aagtggatta aggaaaatta tatcgatagg
      781 ggaagaactt tccttggaaa caaggcttct ggtatgaatg tggaatatgc ttcagaccct
      841 tattggggcg aaaaaattgc tagtgtgatg atgaaaatca atgagaagct aggtggcaaa
      901 gattagtact ataagtgaat atgatttgag tgaatagtaa gttaaaaatc ctgatttcaa
      961 gtaaaatcag gattttttca tggatgcaat ttttttggag tctggtgtga cgcggagggt
     1021 cttttgtcct gtgtaagtga caaagccggg ttttccacca gttggtttat tgagtttttt
     1081 gacttcaatc atatctacct gcaccagatt cgacaggcgc ccttgagaga agtaggcagc
     1141 taactctgct gcgtctgtct tgactgcatc agatgggtca agatttcctg agatgacaac
     1201 atggcttcca ggaatgtcct tagcatggaa ccaaagttcc tccttgcggg ccattttaaa
     1261 ggtcaattcc tcattttgaa gattgtttcg tccgacatag atgatggttt tgccatcgct
     1321 tgctagatat tgttctagtt ttttgcgttt ctggattttc tcccgttgtc ttctgcggat
     1381 aaaacctgtt tgaatcaatt cttcacggat ttcagcgatt tcttccagtc cagcttggtt
     1441 gaggacggtt tctacacttt ccagatagag aatagtggct ttggtttctt caatcaaatc
     1501 agtcaagtat ttgacagctt ctttgagttt ctgataccgt ttaaaatagc gttgggcatt
     1561 ctggttggga gtcagagcct tatcaagcgc aatcatgata ggttggttgg tatagtagtt
     1621 gtctaggata acctggtctt ggtcgttagg cacttggtgg aggaaggttg tcagcaattc
     1681 tcctttttga cgaaattctt cagcgttgtc tgtcgccagt aactcttttt cctgtttttt
     1741 gagtttgtgt cggtttttct gaagttcatt ttcaacacga cgaatcagtt cactggcctg
     1801 ctgtttgacg cggtcgcgct cagccttatc cttatagtag gtgtccaaca aatcagaaag
     1861 atttgcaaga ggctctccca cctgatttgc aaaaggaact ggactgaagg aagtctcagt
     1921 caagcatggc ttggtttctt gattgaaaaa atttcggaaa gcggaaagtt tttcactaac
     1981 cagtatcctt tccaattcat ttgccgtatc gcgtcccaga ccttgaaaga ggctttgaag
     2041 attttttgct gttagttctt gggtttgcag gatttcaaag agcttttcat ccttgatagt
     2101 aaaaggattg agagattttg tacttggcgg agcgatatag gtcgatcctg gaagtaaggt
     2161 gcggtagcta ttttgtgaaa agccgacgtg tttgataact tcgaggattt tatgactgct
     2221 tttatcgacc agtagaatat tactgtgttt ccccataatt tcgataatca aggtagcctg
     2281 gatatggtct ccaatctcgt ttttattgga aactgtaatt tccacaatac ggtcattttc
     2341 cacttgctca atcgactcaa tcagggcccc ctgcaaatac tttctcaaaa ccatgataaa
     2401 ggtagaaggt tgggctggat tttcaaaagt cgtttgggtc agctgaatgc gtccaaaaac
     2461 tggatgggca gaaaggagca ggcgatggct ttggcgattg ctgcggattt gcaagaccaa
     2521 ctcttgttca aaaggctgat tgattttctg gatgcgacca ttcactaatt cgcttcgcaa
     2581 ttcctcaact atgtggtgta aaaaaaatcc gtcaaatgac atcgttctct ccttgtgatt
     2641 gtattccata gtattatatc aaaaaggtag aataaaatca tggaaatgtg gtataataaa
     2701 gccaagtaaa gagaaacgag aagcacatgt atattgaaat ggtagatgaa actggtcaag
     2761 tttcaaaaga aatgttgcaa caaacccaag aaattttgga atttgcagcc caaaaattag
     2821 gaaaagaaga caaggagatg gcagtcactt ttgtgaccaa tgagcgtagt catgaactta
     2881 atctggagta ccgtgacacc gaccgtccga cagatgtcat cagccttgag tataaaccag
     2941 aattggaaat tgcctttgac gaagaggatt tgcttgaaaa tccagaattg gcagagatga
     3001 tgtctgagtt tgatgcctat attggggaat tgttcatctc tatcgataag gctcatgagc
     3061 aggccgaaga atatggtcac agctttgagc gtgagatggg cttcttggca gtacacggct
     3121 ttttacatat taacggctat gatcactaca ctccggaaga agaagcggag atgttcggtt
     3181 tacaagaaga aattttgaca gcctatggac tcacaagaca ataaacgaaa atggaaaaat
     3241 cgtgacttga tatccagttt agaatttgct ttgacaggta tttttactgc tatcaaggaa
     3301 gaacgcaata tgcgaaaaca cgcagtgacg gctctagtgg tcatccttgc aggttttgtt
     3361 tttcaggtgt cacgaatcga atggctcttt ctcctattga gtattttctt ggtagtagcc
     3421 tttgagatta tcaactctgc tattgaaaat gtggtggatt tggccagtca ctatcacttt
     3481 tccatgctgg ctaaaaatgc caaggatatg gcggctggcg cggtattagt ggtttctctt
     3541 ttcgcagcct taacaggcgc attgattttt ctcccacgaa tctgggattt attattttaa
     3601 acagtaagag gaaattatga cttttaaatc aggctttgta gccattttag gacgtcccaa
     3661 tgttgggaag tcaacctttt taaatcacgt tatggggcaa aagattgcca tcatgagtga
     3721 caaggcgcag acaacgcgca ataaaatcat gggaatttac acgactgata aggagcaaat
     3781 tgtctttatc gacacaccag ggattcacaa acctaaaaca gctctcggag atttcatggt
     3841 tgagtctgcc tacagtaccc ttcgcgaagt ggacaccgtt cttttcatgg tgcctgctga
     3901 tgaagcgcgt ggtaaggggg acgatatgat tatcgagcgt ctcaaggctg ccaaggttcc
     3961 tgtgattttg gtggtgaata aaatcgataa ggtccatcca gaccagctct tgtctcagat
     4021 tgatgacttc cgtaatcaaa tggactttaa ggaaattgtt ccaatctcag cccttcaggg
     4081 aaataacgtg tctcgtctag tggatatttt gagtgaaaat ctggatgaag gtttccaata
     4141 tttcccgtct gatcaaatca cagaccatcc agaacgtttc ttagtttcag aaatggttcg
     4201 cgagaaagtc ttgcacctaa ctcgtgaaga gattccgcat tctgtagcag tagttgttga
     4261 ctctatgaaa cgagacgaag agacagacaa ggttcacatc cgtgcaacca tcatggtcga
     4321 gcgcgatagc caaaaaggga ttatcatcgg taaaggtggc gctatgctta agaaaatcgg
     4381 tagcatggcc cgtcgtgata tcgaactcat gctaggagac aaggtcttcc tagaaacctg
     4441 ggtcaaggtc aagaaaaact ggcgcgataa aaagctagat ttggctgact ttggctataa
     4501 tgaaagagaa tactaagtag aggtaggctc atgcctgctt cttgttttta cagaaggagg
     4561 acttatgcct gaattacctg aggttgaaac cgtttgtcgt ggcttagaaa aattgattat
     4621 aggaaagaag atttcgagta tagaaattcg ctaccacaag atgattaaga cggatttgga
     4681 agagtttcaa agggaattgc ctagtcagat tatcgagtca atgggacgtc gtggaaaata
     4741 tttgcttttc tgcctgacag acaaggtctt gatttcccat ttgcggatgg agggcaagta
     4801 tttttattat ccagaccaag tgcctgaacg caagcatgcc catgttttct tccggtttga
     4861 agatgggggc acgcttgttt atgaggatgt acgcaagttt ggaaccatgg aactcttggt
     4921 gcctgacctt ttagacgcct actttatttc taaaaaatta ggtcctgaac caagcgaaca
     4981 agactttgat ttacaggtct ttcaagctgc ccttgccaag tccaaaaagc ctatcaaatc
     5041 ccatctccta gaccagacct tggtagctgg acttggcaat atctatgtgg atgaggttct
     5101 ctggcgagct caggttcatc cagctagacc ttcccagact ttgacagcag aagaagcgac
     5161 tgccattcat gaccagacca ttgctgtttt gggccaggct gttgaaaaag gcggttccac
     5221 cattcggacc tataccaatg cctttgggga agatggaagc atgcaggatt ttcatcaggt
     5281 ctatgataag actggtcaag aatgtgtacg ctgtggtacc atcattgaga aaattcaact
     5341 aggcggacga ggcacccact tttgtccaaa ctgtcaaagg agggactgat gggaaaaatc
     5401 atcggaatca ctgggggaat tgcctcaggt aagtcaactg tgacaaattt tctaagacag
     5461 caaggctttc aagcagtgga tgccgacgca gtcgtccacc aactacagaa acctggtggt
     5521 cgtctgtttg aggctctagt acagcacttt gggcaagaaa tcattcttga aaacggagaa
     5581 ctcaatcgcc ctctcctagc tagtctcatc ttttcaaatc ctgaagagca aaaatggtct
     5641 aatcaaattc aaggggagat tatccgtgag gaactggcta ctttgagaga acagttggct
     5701 cagacagaag agattttctt catggatatt cccctacttt ttgagcagga ctacagcgat
     5761 tggtttgctg agacttggtt ggtctatgtg gaccgagatg cccaagtaga acgcttaatg
     5821 aaaagggacc agttgtccaa agatgaagct gagtctcgtc tggcagccca gtggccttta
     5881 gaaaaaaaga aagatttggc cagccaggtt cttgataata atggcaatca gaaccaactt
     5941 cttaatcaag tgcatatcct tcttgaggga ggtaggcaag atgacagaga ttaactggaa
     6001 ggataatctg cgtattgcct ggtttggtaa ttttctgaca ggagccagta tttctttggt
     6061 tgtacctttt atgcccatct tcgtggaaaa tctaggtgta gggagtcagc aagtcgcttt
     6121 ttatgcaggc ttagcaattt ctgtctctgc tatttccgcg gcgctctttt ctcctatttg
     6181 gggtattctt gctgacaaat acggccgaaa acccatgatg attcgggcag gtcttgctat
     6241 gactatcact atgggaggct tggcctttgt cccaaatatc tattggttaa tctttcttcg
     6301 tttactaaac ggtgtatttg caggttttgt tcctaatgca acggcactga tagccagtca
     6361 ggttccaaag gagaaatcag gctctgcctt aggtactttg tctacaggcg tagttgcagg
     6421 cactctaact ggtcccttta ttggtggctt tatcgcagaa ttatttggca ttcgtacagt
     6481 tttcttactg gttggtagtt ttctattttt agctgctatt ttgactattt gctttatcaa
     6541 ggaagatttt caaccagtag ccaaggaaaa ggctattcca acaaaggaat tatttacctc
     6601 ggttaaatat ccctatcttt tgctcaatct ctttttaacc agttttgtca tccaattttc
     6661 agctcaatcg attggcccta ttttggctct ttatgtacgc gacttagggc agacagagaa
     6721 tcttcttttt gtctctggtt tgattgtgtc cagtatgggc ttttccagca tgatgagtgc
     6781 aggagtcatg ggcaagctag gtgacaaggt gggcaatcat cgtctcttgg ttgtcgccca
     6841 gttttattca gtcatcatct atctcctctg tgccaatgcc tctagccccc ttcaactagg
     6901 actctatcgt ttcctctttg gattgggaac cggtgccttg attcccgggg ttaatgccct
     6961 actcagcaaa atgactccca aagccggcat ttcgagggtc tttgccttca atcaggtatt
     7021 cttttatctg ggaggtgttg ttggtcccat ggcaggttct gcagtagcag gtcaatttgg
     7081 ctaccatgct gtcttttatg cgacgagcct ttgtgttgcc tttagttgtc tctttaacct
     7141 gattcaattt cgaacattat taaaagtaaa ggaaatctag tgcgagtaaa aattaatctc
     7201 aaatgctcct cttgtggcag tatcaattac ctaaccagta aaaattcaaa aacccatcca
     7261 gacaagattg aggttttaaa gtattgtccc aaggaaagaa aagtaaccct acatcttgaa
     7321 tctaagtaga ttttatggta aaataatagg gattttaagg agtttgatat gtataaccta
     7381 ttattaacca ttttattagt attatctgtt gtgattgtga ttgcaatttt catgcaacca
     7441 accaaaaacc aatccagcaa tgtatttgat gccagttcag gtgatttgtt tgaacgcagt
     7501 aaagctcgcg gttttgaagc tgtaatgcag cgtttgacag ggattttagt ctttttctgg
     7561 ctagccattg ccttagcatt gacggtatta tcaagtagat aagaaaataa tgggcaggac
     7621 taggtctttg cctcttttta tttttaaagg atgtttgaga aggttttaca gtaaaagaaa
     7681 attaaaaaat ctagaaagaa aatatgaaag atagaataaa agaatattta caagacaagg
     7741 gaaaggtgac tgttaatgat ttggctcagg ctttgggaaa agacagttcc aaggattttc
     7801 gtgagttgat taaaaccttg tccttaatgg aaagaaagca ccaaattcgt tttgaagaag
     7861 atggtagtct gaaattagaa attaagaaaa aacatgagat taccctcaag gggatttttc
     7921 atgcccataa aaatggcttt ggctttgtta gtctggaagg cgaggaggac gacctttttg
     7981 tagggaaaaa tgatgtcaac tatgctattg ctggtgatac cgtcgaggta gtgattaaga
     8041 aagtcgctga ccgcaataag ggaacagcag cagaagccaa aattattgat atcctagaac
     8101 acagtttgac aacagttgtc gggcaaatcg ttctggatca ggaaaaacct aagtatgctg
     8161 gctatattcg ttcaaaaaat cagaaaatca gtcaaccgat ttatgttaag aaaccagccc
     8221 taaaattaga aggaacagaa gttctcaaag tctttatcga taaataccca agcaagaaac
     8281 atgatttctt tgtcgcgagt gttctcgatg tggtgggaca ctcaacggat gtcggaattg
     8341 atgttcttga ggttttggaa tcaatggaca ttgtatccga gtttccagaa gctgttgtta
     8401 aggaagcaga aagtgtgcct gatgctccgt ctcaaaagga tatggaaggt cgtctggatc
     8461 taagagatga aattaccttt accattgacg gtgcggatgc caaggacttg gacgatgcag
     8521 tgcatatcaa ggctctgaaa aatggcaatc tggagcttgg ggttcacatc gcagatgttt
     8581 cttattatgt gaccgagggg tctgcccttg acaaggaagc ccttaaccgt gcgacttctg
     8641 tttacgtgac agaccgagtg gtgccaatgc ttccagaacg actatcaaat ggcatctgct
     8701 ctctcaatcc ccaagttgac cgcctgaccc agtctgctat tatggagatt gataaacatg
     8761 gtcgtgtggt caactatacc attacacaaa cagttatcaa gaccagtttt cgtatgacct
     8821 atagcgatgt caatgatatc ctagctggcg atgaagaaaa gagaaaaaaa tatcataaaa
     8881 ttgtaccaag tatcgaactc atggccaagc ttcatgaaac tttagaaaac atgcgtgtga
     8941 aacgtggagc tctcaatttt gataccaatg aagcgaagat tttagtggat aaacaaggta
     9001 agcctgttga tatcgttctt cggcagcgtg gtattgccga gcggatgatt gagtctttta
     9061 tgttgatggc taatgaaaca gttgccgaac atttcagcaa gttggatttg ccttttatct
     9121 atcgaattca cgaggagcct aaggctgaaa aggttcagaa gtttattgat tatgcttcga
     9181 gttttggctt gcgcatttat gggactgcca gtgagattag tcaggaggca cttcaagaca
     9241 tcatgcgtgc tgttgaggga gaatcttatg cagatgtatt gtccatgatg cttcttcgct
     9301 ctatgcagca ggctcgttat tcggagcaca attacggcca ctatggacta gctgctgact
     9361 attatactca ctttaccagt ccaattcgtc gttatccaga ccttcttgtt caccgtatga
     9421 ttcgggatta cggccgttct aaggaaatag cagagcattt tgaacaagtg attccagaga
     9481 ttgcgaccca gtcttccaac cgtgaacgtc gtgccataga agctgagcgt gaagtcgaag
     9541 ccatgaaaaa ggctgagtat atggaagaat acgtgggtga agagtatgat gcagttgtat
     9601 caagtattgt caaattcggt ctctttgtcg aattgccaaa cacagttgaa ggcttgattc
     9661 acatcactaa tctacctgaa ttttatcatt tcaatgagcg tgatttgact cttcgtggag
     9721 aaaaatcagg tatcactttc cgagtgggtc agcagatccg tatccgtgtt gaaagagcgg
     9781 ataaaatgac tggagagatt gatttttcat tcgtacctag tgagtttgat gtgattgaaa
     9841 aaggcttgaa acagtctagt cgtagtggca gagggcgtgg ttcaaatcgt cgttcggata
     9901 agaaggaaga caagagaaaa tcaggacgct caaatgataa gcgtaagcat tcacaaaaag
     9961 acaagaagaa aaaaggaaag aaaccttttt acaaggaagt agctaagaaa ggagccaagc
    10021 atggcaaagg gcgagggaaa ggtcgtcgca caaaataaaa aggcacgcca cgactataca
    10081 atcgtagata cgctagaggc agggatggtc ctgactggaa ctgaaatcaa gagtgtacga
    10141 gctgctcgaa ttaatctcaa ggatggcttt gctcaagtga aaaatggaga agtttggctg
    10201 agcaatgttc atatcgcgcc ttacgaagag ggcaatatct ggaaccagga accagaacgt
    10261 cgtcgtaaac tcctgctcca taaaaggcaa attcaaaaat tggaacaaga gaccaaaggg
    10321 acaggaatga ccttagttcc ccttaaggtc tatataaaag atggctacgc taagcttctt
    10381 ttaggacttg ccaaagggaa gcatgactat gacaaacggg agtctatcaa acgtcgtgag
    10441 caaaatcgag atatcgcgcg tgtgatgaaa gctgttaatc agcgataaaa agaggaattg
    10501 aaaatggaaa aattagttgc ctataaacgc atgcctttgt ggaataaaca aacaatgcct
    10561 gaagctgttc agcaaaagca caatacaaaa gttgggactt gggggaaaat tactgtcttg
    10621 aagggagctc tcaagtttat tgaattgaca gaagaagggg aagttctagc tgaacacctc
    10681 tttgaagcag gggcagacaa tccaatggcc caacctcaag cctggcaccg agtggaagct
    10741 gccacagatg atgtggaatg gtacttggaa ttttattgta aacctgagga ttattttgct
    10801 aaaaaataca ataccaatcc tgttcattca gaggtcctag aggccatgga gacagtgaaa
    10861 caagggaaag ctttggattt gggttgtggt caggggcgta attctctttt tctagcccag
    10921 caagattttg atgtgacggc tgtagatcaa aatggactag ctcttgaaat cttgcaaagc
    10981 attgtggagc aggaagattt ggacatgcct gttggccttt acgatatcaa ttcagctagc
    11041 attgaacaag aatatgattt tatcgtttca acagttgttc tcatgtttct acaagcggac
    11101 cgcattccag ctattattca aaatatgcag gagaaaacca gtgttggtgg ttacaacctt
    11161 atcgtttgtg ccatggacac ggaggattat ccttgctcgg ttaacttccc attcaccttt
    11221 aaagaaggag aactggcaga ctattacaag gattgggaat tggttaagta caatgaaaat
    11281 ccaggccatt tgcaccgtcg cgatgagaat ggcaatcgta ttcaactacg ctttgcgacc
    11341 ttactagcta agaaaatcaa gtaaacacac atgaagatta ggaattttcc tgatcttttt
    11401 tcttttttac gaatgatata gaaaaggagg gaattcatgt ttgttgcgag agatgctagg
    11461 ggagaattgg taaatgtgtt agaggataaa cttgagaagc aagcatacac ctgcccagct
    11521 tgtggaggcc agctccattt gcgtcaagga ccaagtgtac ggacgcattt tgcccataaa
    11581 tccttaaaag actgtgattt tttctttgaa aatgaaagtc cagaacacct ggccaataag
    11641 gaatccctct atcactggtt gaaaaaagag acaaaggttc aattagagta cccgctttca
    11701 gaacttaaac agattgcgga tgtatttgta aatggcaatc tagctctaga agttcagtgt
    11761 agtcccttgc ctcagaaagt ccttaaagag cgaagtgagg gatatcgtag tcagggttac
    11821 caagtactgt ggttgctggg tcaaaaactg tggctcaagg agcgtttgac tcgtctacag
    11881 caaggttttc tttatttcag tcaaaacatg ggcttttatg tttgggaatt agacaaggaa
    11941 aaacaagttt taagactcaa atacctgatt taccaggatc tccgcggtaa actccattat
    12001 caaatcaagg aattttccta tggtcaaggt agtttattgg aaatattgcg tcttccctat
    12061 aagagacaaa aaatatctca ttttacagtt tctgaggaca aggacatctg tcgctatatc
    12121 cggcaacaac tttattatca aaatctcttt tggatgaaag aacaagcaga agcctatcaa
    12181 aagggagaaa atatcctgac ttatggactg aaagaatggt atccacaaat tcgaccaata
    12241 gtgggcaaat ttttccagat tgaacaagac ttgactagct attatcagca cttttatacc
    12301 tattaccaaa aaaatcctca aaatgattgg caaaagcttt atccaccagc cttttatcag
    12361 caatatttct tgaaaaatat ggtagaatag aaaggatgga ggaatctaat ggtattacaa
    12421 agaaatgaaa taaatgaaaa agatacatgg gatctatcaa cgatctaccc aactgaccag
    12481 gcttgggaag aagccttaaa agatttaaca gaacaattgg agacagtagc ccagtatgaa
    12541 ggccatctct tggatagtgc ggataaccta ctagaaatca ctgaattttc tcttgaaatg
    12601 gaacgccaga tagagaagct ttacgtttat gctcatatga agaatgacca ggatacacgt
    12661 gaagctaagt atcaagagta ctatgccaag gccatgacac tctacagcca gttagaccaa
    12721 gccttttcat tctatgagcc tgaatttatg gagattagcg aaaagcagta tgctgacttt
    12781 ttagaagctc aaccaaagct gcaggtttat caacactatt ttgacaagct cttgcaaggc
    12841 aaggatcacg ttctctcaca acgtgaagaa gaattattgg ctggagctgg agaaatcttt
    12901 ggttcagcaa gtgaaacctt tgctatcttg gacaatgcgg atattgtgtt cccttatgtc
    12961 ctagacgatg atggtaaaga agttcagcta tctcatggga cttacacacg tttgatggag
    13021 tctaaaaaac gtgaggttcg tcgtggtgcc tatcaagctc tttatgcgac ttacgaacaa
    13081 ttccaacaca cctatgccaa aaccttgcaa accaatgtta aggtgcaaaa ttaccgtgct
    13141 aaagttcgta actacaagag tgctcgtcat gcagccctcg cagcgaattt tgttccagaa
    13201 agtgtttatg acaatttggt agcagcagtt cgcaagcatt tgccactctt acatcgctat
    13261 cttgagcttc gttcaaaaat cttggggatt tcagatctca agatgtacga tgtctacaca
    13321 ccgctttcat ctgttgaata cagttttacc taccaagaag ccttgaaaaa agcagaagat
    13381 gctttggcag tcttgggtga ggattacttg agccgtgtta aacgtgcctt cagcgagcgt
    13441 tggattgatg tttacgaaaa tcaaggcaag cgttcaggtg cctactctgg tggttcttac
    13501 gataccaatg cctttatgct tctcaactgg caggacaatc tggacaatct ctttactctt
    13561 gttcatgaaa caggtcacag tatgcattca agctatactc gtgaaactca gccttatgtt
    13621 tacggagatt actctatctt tttggctgag attgcctcaa ctaccaatga aaatatcttg
    13681 acggagaaat tattggaaga agtggaagac gacgcaacac gctttgctat tctcaataac
    13741 ttcctagatg gtttccgtgg aacagttttc cgccaaactc aatttgctga gtttgaacac
    13801 gccattcacc aagcagatca aaatggggag gtcttgacaa gcgatttcct aaataaactc
    13861 tacgcagact tgaaccaaga gtattatggt ttgagtaagg aagacaatcc tgaaatccaa
    13921 tacgagtggg ctcgtattcc acacttctac tataactact atgtatatca atattcaact
    13981 ggctttgcgg ccgcctcagc cttggctgaa aaaattgtcc atggtagtca agaagaccgt
    14041 gaccgctata tcgactacct caaggcaggt aagtcggact atccacttaa tgtcatgaga
    14101 aaagctggtg ttgatatgga gaaggaagac tacctcaacg atgcctttgc agtctttgaa
    14161 cgccgtttaa atgagtttga agcccttgtt gaaaaattag gattggcata aaatggttga
    14221 atcgtatagt aagaatgcta accataacat gcgtcgtcct gtcgtcaaag aagaaattgt
    14281 agacttgatg cgtcagcgtc aaaagcaggt cacaggtttc ttgaaagaat tggaagactt
    14341 tgcccgcaag gaaaatattc ctattattcc ccatgaaacg gttgcttatt tccgttttct
    14401 tatggaaacc atgcagccta aaaatattct ggaaattggg acggctatcg gtttttcagc
    14461 tctcttgatg gctgaacatg cgccaaatgc taagattaca actattgatc gtaatccaga
    14521 aatgattggt tttgccaagg aaaattttgc ccagtttgac agtcgcaagc aaatcactct
    14581 cctagaggga gatgcggtgg atgtcttatc tacactgaca gagtcttatg atttcgtctt
    14641 tatggattct gccaagtcta aatacatcgt ctttctgcca gaaatcctca aacatttgga
    14701 agttggtggt gtggttgtct tggatgatat ttttcaaggt ggtgatgttg ccaaggatat
    14761 tatggaagtc cgtcgtggtc agcgaaccat ttatcgaggc cttcaaaaat tatttgatgc
    14821 aaccttagac aatccagaac tcaccgcaac attagtgcct ttaggagatg gtattctcat
    14881 gcttcgtaaa aatgtagcag atgttcaact gtctgaaagc gaatgatttt cagaaaaatt
    14941 taagaaaaaa tagtaaaata gatagagtaa cacttatctc aaaggagtag acatgaagaa
    15001 aaaattattg gcaggtgcca tcacactatt atcagtagca actttagcag cttgttcgaa
    15061 agggtcagaa ggggcagacc ttatcagcat gaaaggggat atcatcacag aacatcaatt
    15121 ttatgagcaa gtgaaaaaca acccttcagc ccaacaagtc ttgttaaata tgaccatcca
    15181 aaaagttttt gaaaaacaat atggctcaga gcttgatgat aaagaggttg atgatactat
    15241 tgccgaagaa aaaaaacaat atggcgaaaa ctaccaacgt gtcttgtcac aagcaggtat
    15301 gactcttgaa acacgtaaag ctcaaattcg tacaagtaaa ttagttgagt tggcagttaa
    15361 gaaggtagca gaagctgaat tgacagatga agcctataag aaagcctttg atgagtacac
    15421 tccagatgta acggctcaaa tcatccgtct taataatgaa gataaggcca aagaagttct
    15481 cgaaaaagcc aaggcagaag gtgctgattt tgctcaatta gccaaagata attcaactga
    15541 tgaaaaaaca aaagaaaatg gtggagaaat tacctttgat tctgcttcaa cagaagtacc
    15601 tgagcaagtc aaaaaagccg ctttcgcttt agatgtggat ggtgtttctg atgtgattac
    15661 agcaactggc acacaagcct acagtagcca atattacatt gtaaaactca ctaagaaaac
    15721 agaaaaatca tctaatattg atgactacaa agaaaaatta aaaactgtta tcttgactca
    15781 aaaacaaaat gattcaacat ttgttcaaag cattatcgga aaagaattgc aagcagccaa
    15841 tatcaaggtt aaggaccaag ccttccaaaa tatctttacc caatatatcg gtggtggaga
    15901 ttcaagctca agcagtagta catcaaacga atagtccaaa tcaatgagtc agggaaaaaa
    15961 actcgacttc aggaaaaaat gaagcacaca ttcccacaat aaaacgcata gtacaaggtt
    16021 tgtactgacc ccaaaagtta gacaattaat ttatctgaag gatttagttc tgtattgcac
    16081 agggctaagt ccttttagtt ttaccttaat tctcttattg ttgtaataat caatatagtc
    16141 tataatggct tgttccaatt gattaagtga tttaaatgtt tgctcatagc cataaaacat
    16201 ttcggatttt aaaatgccaa agaaagattc catcctatcg ttgtcttggc tgtttccttt
    16261 gcgtgacata gatgcttgaa ttcccttact ctctaggaag caatgataag aatcgtgttg
    16321 gtattgccag ccttggtcac tatggagaat cgtattctcg tagtgcttct ctttgaatgc
    16381 ctgttccaac attaacgatc aatcaattta atcatgtacc taatattaga attgtttatc
    16441 ccaaa
//
LOCUS       DAVBOG010000047        15844 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.047, whole genome shotgun sequence.
ACCESSION   DAVBOG010000047 DAVBOG010000000
VERSION     DAVBOG010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 15844)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15844)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15844
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.047"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ865_001701"
     CDS             complement(<1..1205)
                     /gene="dcm"
                     /locus_tag="VQ865_001701"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
                     /protein_id="HET3136011.1"
                     /translation="MRFIDLFSGIGGFRLGMESVGHECIGFCEIDKFARKSYKSIFQT
                     EGEIEFHDIRDVSDAEFKKLRGKVDIICGGFPCQAFSIAGRRLGFEDTRGTLFFEIAR
                     AAKQIQPRFLFLENVKGLLNHDKGRTFTTILTTLDELGFDVEWQLLNSKDFGVPQNRE
                     RVFIIGHSRKRGTRLLFPFRREGQTTNSETLKTLGNLNPSKSGMSGKVYYSEGLAPTL
                     VRGKGEGFKVAIPCMTPDRLDKRQNGRRFKENQEPMFTLNTQDRHGIVVVGDLPTSFK
                     ETGRVYGSEGLSPTLTTMQGGDKIPKILIPEPIQFLKVREATKKGYAQAEIGDSINLE
                     RPSSQYRRGRVGKGIANTLTTSGQMGVVVASYEGEDKQVYHVAGVLIDGQFYRLRIRR
                     ITPKECFRL"
     gene            complement(1304..2083)
                     /locus_tag="VQ865_001702"
     CDS             complement(1304..2083)
                     /locus_tag="VQ865_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3136012.1"
                     /translation="MKRITANQYQTSERYYKLPKILFEDEKYMDMKLEVKVAYSILKD
                     RLELSLSRGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKILKEYDLIDEVQQSSS
                     EKGRLANKIYLGELSSTPVGNSNRPSVKKRLGQVENETAPVSHSAPRETEVSETKYSE
                     TDSLFIEDEEDRNTQPILKRKVEKVTKYDRDYIWGLVQDQFRREGFSETASEIAMTDF
                     ERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGGG"
     gene            complement(2080..2253)
                     /locus_tag="VQ865_001703"
     CDS             complement(2080..2253)
                     /locus_tag="VQ865_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136013.1"
                     /translation="MTKELQSSRYIVISFLVREMGIDIVEAISLMAELEKSGLVQLES
                     SGDLTLKELGGAL"
     gene            complement(2783..7996)
                     /locus_tag="VQ865_001704"
     CDS             complement(2783..7996)
                     /locus_tag="VQ865_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000054791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3136014.1"
                     /translation="MSLLKKDKFSIRKIKGIVGSVFLGSLLFAPSVVGASTYHYLDYS
                     SLTQTERDQLKQGRPDESKESYALDYEKDALPNTGSSQSIMTALGLLAIGSLIVIITK
                     DNRNKKIATFLIVGATGLVTLSTASALNLNANIHESGRDGVLQISGYRYVGYLELDDK
                     TVSSVSPASTVSPVEQPKVVTEKGEPEVHEKPDYTQPIGANLVEPEVHEKLAYTEPVG
                     TTGVDENGNLIEPPVNDIPEYTEPVGTTGVDENGNLIEPPVSDIPEYTEPISTVSEVA
                     SEREELPSLHTDIRTETIPKTTIEESDPSKFIGDDSVRQVGEDGERQIVTSYEELHGK
                     KISDPVETVTILKEMKPKILVKGTKEKPKEKTAPVLTLDRTNTNVLNRSATLSYHLVN
                     TDGVTINKITATIKDGNEIVKTVDLTSEQLDKQVEDLKFYKDYKIETTMTYDRGKGEE
                     TATLEEKPLRLDLKKVEIKNIASTNLVKVNDDGTETPSDFMTEKPSDEDVKKMYLKIT
                     SRDNKVTRLAVDKIEEVTEEGKKLYKITAEAQDLIQHTDPTKVRNKYVHYIEKPVPKV
                     DDVYYNFKELVDAMNADKNGTFKIGADLNATNVPTPNKQYVPGTFKGHLSSVDGKQYT
                     IHNIARPLFDRVENGSVKNINLGNVDINMPWADGIAPVANMVKNATVEDVKVTGNVVA
                     NNNIAGIVNKIDSGGQLTNVAFIGNLTGVGDKGQYMAGIAGEIWRGNLAKAYVEADIV
                     ANRARIGGLVAKTDNGNDSMGIGKYGSIRKSVTKGTIKTKVLFETGGFINSNLPFGKL
                     EDNISMMRVENGEEFFGSSDLDYDGGYFTNGWLERNFVVKGVSSGKHSYKRSRDKIKE
                     ISQDEANKRIANFGLTADKYEINEPVVNRLNRLTRREDEYKSTQDYKSERDLAYRNIE
                     KLQPFYNKEWIVNQGNKLAEDSNLAKKEVLSVTGMKDGQFVTDLSDIDKIMVHYADGT
                     KEEMDVTKNTDSKVQQVREYSVSGLGDVVYTPNMVVKNRDKLIADVKSQLSSVELISQ
                     EVRDLMSRRDKPAENTDERKNGYIKDLYLEESFAEVKQNLDKLVKSLVENEDHQLNGD
                     EAAIKSLLKKVETNKAKIMMALTYLNRYYDIKYGDISIKNIMMFKPDFYGKTPSVIDR
                     LINIGSSEKNLKGDRTQDAYREIIAGNTGKSNLRNFLEYNMRLFTEDKDINDWFIHSA
                     KNVYVSEPKTTNTELKDKRHRVFDGLDNGVHGRMILPLLTLKDAHMFLISTYNTMAYS
                     SFEKYGKHTEEARNEFKTKIDEVAHAQQTYLDFWSRLALPNVRDRLLKSQNMVPTPVW
                     DNQTYNGSPVGRRGFDSKGNPIAPIRELYGPTWRHHDRDWRMGAMASIFPNPNNDDKV
                     LFMVTDMISPFGISAFTHETTHVNDRMLYFGGHKHRQGTDVEAYAQGMLQTPDSSTTN
                     GEYGALGINMAYHRPNDGNQWYNPDPDKLKTRDDIDRYMRNYNEAMMLLDHVEADAVL
                     PKIKGDNSKWFKKIDKEMRSKIQYNDLLGPNQWDSIRDLKDEEKVMTLSSVNDLVDNN
                     FMTKHGNPGNGRYRPEDFTPNSAYVNVNMMAGIYGGNTSQGAPGSLSFKHNAFRMWGY
                     YGYENGFISYVSNKYKAEADKNNHGLLSDKLIINKVSKGNFNTLEEWKRHWYGEVLAK
                     AKKGFEAIDIDGVHISNYDELRPLFDKAVEEDLKKPDDFSHTVALKSKVFKALLKNTD
                     GFFNKLFKEDI"
     gene            complement(8040..14399)
                     /locus_tag="VQ865_001705"
     CDS             complement(8040..14399)
                     /locus_tag="VQ865_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001845810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G5 domain-containing protein"
                     /protein_id="HET3136015.1"
                     /translation="MEKYFGEKQERFSFRKLSVGLVSATISSLFFMSVLASSSVDAQE
                     TAGVHYKYVADSELSSEEKKQLVYDIPTYVENDDETYYLVYKLNSQNQLAELPNTGSK
                     NERQALVSGASLAALGILIFAVSKKKVKNKTVLHLVLVAGMGNGVLVSVHALENHLLL
                     NYNTDYELTSGEKLPLPKEISGYTYIGYIKEGKTTSDFEVSNQEKSAATPTKQQKVDY
                     NVTPNFVDHPSTVQAIQEQTPVSSTKPTEVQVVEKPFSTELINPRKEEKQSSDSQEQL
                     AEHKNLETKKEEKISPKEKTGVNTLNPQDEVLSGQLNKPELLYRDETIETKIDFQEEI
                     QENPDLAEGTVRVKQEGALGKKVEIVRIFSVNNEEVSREIISTSTTAPVSRIVEKGTK
                     KAQVIKEQAETGAEHKEVQSGAIVEPAIQPELPAAVLTDKGESAVQPELPEAVVSDKG
                     VPEVQPALPEAVMTDKGDPEQVEPLPEYTGVQAGAIVEPEKVEPEYAGVQAGAIVEPE
                     QVAPLPEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVEPEKVEAPKEYTGVQAGAIVE
                     PEKVEALKEYTGKIEQPSAEDTKPNNENTNTPEEMSIQKKSSALINMNFITDSSKVTG
                     VGSATFIAPNVLLTVAHNFINNSTDNTTGEFRGDKSKNVYEWVTPDGQKGTFTANNIH
                     FYNKKDYPKGFIYDLAVIKLPETTGREHVELVKNYSKVNLNDKLNVHGYPAGKYTHLK
                     DATVEMEQEYANNTYGVQYQGGNPGMSGGGIFNANGEVIGVHQNGAQNRSGGLILSPT
                     QLAWIKSIIAGNEIPPVYDELYRHKDEKKDDAKDEKEVIKKLELRNISSVELYSKDGN
                     KYRHVTSLASLPSNAENYFMKVKSENFKDVMLPVTSITNDTKDNRDVYKIVASANSLI
                     QHENNNVLENYTYYLPKTQQSETGVYTSFKNLVDAMNSNPNGTFRLGATMDAREVELP
                     DGQESYVNNVFHGILVGTNNEKYYAIYNLKKPLFGELNGATVEKLSLKDVNISAKDDT
                     ATLAKEANNNTHIDNVHADGAIAGERSIGGLVSQVNNSTISNSSYTGRITNTYKTVAS
                     YQIGGLVGKLSGPRGLIDKSFASIDLSSNATQGDQSIGGIVGAVENSALISNSYAEGN
                     LNNVQRFANVGGVVGNLWDPVGGLEKSGRLSNVLSDVNVTNGNAIAGYNFNGIKANGT
                     YSNKNNKVVNVVQEDDEILTKDSTVQRGEVLEDAQIKEKKATFVSKNTIKTEDFNFSS
                     RYVTDYKNLENADSSKEKVYKNIEKLLPFYNRETIVKYGNLVETSSNLYNKELLSVVP
                     MKDKEVISDINKNKSSINKLLLYYADNTSETLNVNYQTDFSNVAEYRIGGTNLIYTPN
                     TLLRNYQNILDEVLPALNSVEYKSEAIRKVLDVSKDVSLTELYLEEQFNTTKTNLKDS
                     LTKLLTADAAIAENNNKVIDNYVIEKIKNNKEALLLGLTYLERWYDFKYRDTKAKDLV
                     MYHLDFFGKSNSSALDNVIELGKSGYNNLLAKNNVITYNVLLAKNYKTNNLFDALEKY
                     RKAFVPDKTNNEWFKEQTKAYIVEEKSTIKEVSDKQSIAGSPYSIGVYDRLTSPSWKY
                     PSMVLPLLTLPEKSVFIIANISTIGFGAYDRYRSKEHPAGTDLNDYVEKKAKEAAVRF
                     RDHYDYWYRILDDKNKEKLYRSVLVYDAFRFGTDEKEDKDTYQATFETNHPAIKHFFG
                     PAGNNVVHNSNGAYATGDAFYYMAYRMLDKDGAVTYTHEMTHNSDREIYLGGYGRRNG
                     LGPEFYAKGLLQAPDHPNDPTVTINSILKYDQSEESTRLQVADPTQRFGSVDDLNKYM
                     HNMFDVIYMLEILEGKAVAKLDTNQKYDLLRKIENEYKPDPDGNSVYATNVVRRLKPE
                     ELTKLTTFNSLIEHDIITRRGYVDEATYKRNGYYTINLFSPIYSALSSKIGTPGDLMG
                     RRIAFELLAAKGYKDGMVPYISNQYEKEAKAQGKVITSYGKQIGLVTDEIVLSKVFNN
                     QYNSWIDFKKDMYKEREDKFGKLNKVSFIDPNGSWARQQKVTIDNINRLEKMIEDAVK
                     FDAEDEVAKLYPETNSRVLKLKKAIFKAYLDQTGDFRSSIFENKK"
     gene            complement(14608..15786)
                     /locus_tag="VQ865_001706"
     CDS             complement(14608..15786)
                     /locus_tag="VQ865_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136016.1"
                     /translation="MTLPVRKSLHDAVLQASKADTWEQATKEWNEVSLIFNGIGRSNC
                     VCGNAIKYAYELFNGVTGQRLFPIGSDCVRHFHRLSLDQQLEEEEKLLRKVENLTRKA
                     QKKEKIKVNKSDFDERLLKWLWEKGVFKPNRGNQFAPERDYQLFLEVFQGGSWTKAEP
                     KKKARMEEVLEKCIKPFLLGKSDDQLYLVKLGKEKIDYEQELRIQAEKERKKRDKIAK
                     QYADNLVLAMGPAERAYQDYFGFTETLTQEERKWEKILFGKNRAERAIKAKQYQKELE
                     KDQRIASQDPIERKQKQTWLLNSYFRELPEEKARFSRLLLEYRKSGEVPFSTEYLSDH
                     LIDFFYKMKAFEFEIAPEQVRDFLKKSLQEDHRSSAQGSWIEGILLNCLKPFLERLVI
                     "
BASE COUNT         4479 a         3217 c         2367 g         5781 t
ORIGIN      
        1 tgcagtcgaa aacactcttt aggagtgatt cgtcgtattc tcaaacggta aaattgtcca
       61 tctattaaaa caccagctac atggtaaact tgtttatctt ctccttcata gctagccact
      121 actactccca tttgaccact agttgttaat gtattcgcta taccttttcc aactctacca
      181 cgacgatact gagaacttgg tctttctaaa ttgattgaat ctccaatctc tgcttgagca
      241 tacccttttt tagttgcttc ccggactttt agaaattgga ttggttctgg aatcagtatt
      301 ttgggaattt tatctcctcc ttgcatcgta gtcagtgttg gagataagcc ctcgcttcca
      361 tagactcgac ctgtctcctt aaagctagtc ggtaaatctc caacaacgac aataccatga
      421 cgatcctgag tatttaaagt aaacatcggc tcttggtttt ccttaaagcg tctcccattt
      481 tgtctcttgt ctaatctgtc tggtgtcata caaggaatcg caaccttgaa tccttctcct
      541 tttccacgaa ctaaggttgg tgcaagacct tctgaataat agactttacc gctcattcca
      601 ctttttgatg gattcaaatt ccctagtgtt tttaaagtct cagagttagt tgtttgacct
      661 tctcgtctga aaggaaataa gagtctggta cctctctttc tagaatgtcc gataataaac
      721 accctctctc tgttttgggg aacgccaaaa tccttactgt taagcaactg ccactcaaca
      781 tcaaacccca actcatcaag tgtggtaagg attgtggtga acgtccgtcc cttatcgtga
      841 ttgagtaggc ctttaacatt ttcaagaaaa agaaaacgtg gttggatttg tttggccgcc
      901 cgagcaattt caaagaacaa agttcctcta gtatcttcaa atcccaatcg tcttcctgcg
      961 attgaaaatg cttgacaagg gaatccccca cagatgatat cgactttccc tctaagtttt
     1021 ttaaattctg catctgaaac atctcgtatg tcatgaaatt ctatttctcc ttccgtttga
     1081 aaaatggact tataagattt cctagcaaat ttatcaatct cacaaaatcc aatacactcg
     1141 tgtccaacac tttccattcc aagtcgaaat ccacctatac ctgaaaataa atcaataaat
     1201 ctcatttctt gatcacctct ttcttatcga ctaccattgt cataactgtc actccacttg
     1261 aaatgacaat aagcataact aatatccact cgattgacga catttaacca cctccttttc
     1321 taacacggtt attccaaaca gaatacaggc cattaaacac aaattcagca agtacttccg
     1381 ctcgtctaac aaagcgaaca ttgtcaagag catactgata gattctttca aaatcagtca
     1441 tagcaatttc actggctgtt tcagaaaaac cttctcgtct aaattgatct tgtaccaatc
     1501 cccaaatata atctcgatca tattttgtga ccttttctac ttttcttttc aaaataggtt
     1561 gagtattcct atcctcctca tcctcaataa ataaagaatc agtctcacta tatttagtct
     1621 cactaacttc agtctctcta ggggctgaat gtgagactgg ggccgtttca ttttcaacct
     1681 gccctagtct ttttttaaca ctaggcctgt ttgaattacc tactggggta gaagataatt
     1741 cccctaaata aatcttatta gctagtcttc ctttctcact tgaagactgt tgaacttcat
     1801 caattaagtc atattcttta agaatttttt tgatagacag taattttgac ttcgagcaac
     1861 ctaacagctt catcagttta gaattagaaa atactaaata aaccgctcct tcttcatcta
     1921 tccaaccacg actgagagat aattctaaac gatcttttaa aatagaataa gccaccttta
     1981 cttctagttt catatccata tatttctcat cctcaaaaag aattttaggt aatttgtaat
     2041 accgttctga agtttggtat tgatttgcgg taattcgttt catagcgcac ctccaagttc
     2101 tttgagtgtt aaatctccgc ttgattccaa ttgaaccaag ccactttttt ccaattcagc
     2161 cataagagag atggcttcaa caatgtcaat tcccatttca cgtactaaaa atgaaatgac
     2221 aatatagcgt gatgattgta attcttttgt cattttccct cctgaaaata aaaaaaacgg
     2281 aaagattgtg aaattccttt ccgtaacata ataaatattt gaacaccaaa ctcaacacca
     2341 aaaaaatgtt tttattgata attattgctc aatcaagcac ttataacaat gtaaaaaata
     2401 aaaatctgta ctcacaaaaa cccttgaaat tcaagggttt taagcattta ttctacttca
     2461 caatgtttta ttattttaaa tcttctagac caaccattga atagtagcca ttgagttttt
     2521 tcctttcgta gcaaggattt agatccccta ttttatttta ctatagtttg aacatagaga
     2581 gttttcaaat gaatgatgtc caaacagttc ttgttttatg acatagaaat ctactttata
     2641 ttatatcatg ccttctttat tttgtccgat gatagccttt taccctatct tttagcctat
     2701 cttttaccct atatagaaaa aagccatcaa atgatgactt ttcagaggga gcaaaaaact
     2761 gttccttcta tattctaaac atttaaatgt cttctttaaa cagtttatta aagaaaccgt
     2821 ctgtgttttt aagaagggct ttgaagacct tagatttaag agcaacagtg tgagagaagt
     2881 catctggttt cttcaaatct tcttcaactg ctttatcaaa taaaggcctt aactcatcat
     2941 agttactgat atggacgcca tcaatatcga tagcctcaaa acctttctta gctttagcaa
     3001 gaacttcccc gtaccaatgt ctcttccact cttcaagagt attaaagttt cctttcgata
     3061 ctttattaat tattagctta tcgcttagta aaccgtggtt gtttttatct gcttctgctt
     3121 tgtatttatt tgatacataa ctaataaagc cattttcata accataatag ccccacatac
     3181 ggaaagcatt gtgcttaaat gataatgaac caggagcacc ttgactcgta ttcccaccgt
     3241 aaattcctgc catcatattg acatttacgt aagctgagtt tggtgtaaaa tcttctggtc
     3301 tataacgtcc attacctgga tttccatgtt ttgtcatgaa gttattatcc actaaatcat
     3361 tgacgctaga taaagtcatt accttttctt catctttcaa atcacggata ctatcccatt
     3421 ggtttggacc taaaagatca ttatactgaa tcttagagcg catttctttg tcaatcttct
     3481 tgaaccactt actattgtct cctttaattt taggaagtac agcatcagct tctacatgat
     3541 caagcaacat catagcttca ttgtagtttc tcatgtagcg gtcaatgtca tcacgtgtct
     3601 ttaatttgtc aggatctggg ttgtaccatt ggttaccatc atttggacga tggtaagcca
     3661 tgttaattcc aagtgcgccg tattcaccat tagtcgttga gctgtcaggt gtttgcaaca
     3721 taccttgagc ataggcttca acgtctgtac cttgacgatg cttatgacca ccgaagtaaa
     3781 gcattctatc gtttacgtgt gttgtttcgt gagtaaaggc tgaaatacca aatgggctaa
     3841 tcatatccgt caccataaac aagaccttgt catcattatt tggattaggg aatattgatg
     3901 ccatagcgcc catacgccag tctctatcat ggtgtcgcca tgttggacca tataattcac
     3961 gaattggagc tatagggtta cctttactgt caaatcctcg acgacctaca ggagaaccat
     4021 tgtaggtctg gttatcccaa actggtgtcg gtaccatatt ttgactctta agaagtctat
     4081 cacgaacatt aggcagagct aatctggacc agaaatctaa ataagtttgt tgagcatgtg
     4141 caacttcatc aatcttagtt ttgaactcat tacgagcttc ttctgtatgt tttccatatt
     4201 tctcaaatga actgtacgcc atcgtgttat atgttgaaat taagaacata tgggcatctt
     4261 taagcgttag aagtggtaaa atcatacgac catgaacacc gttatctaaa ccatcgaaca
     4321 cacgatgacg tttatctttc aactctgtat ttgttgtctt aggttctgaa acataaacat
     4381 tcttagctga gtggataaac caatcattga tgtctttatc ctctgtaaac agacgcatgt
     4441 tgtattctaa gaagttacgc aaattacttt taccagtatt acctgcgatg atttcacggt
     4501 aagcatcctg agtccgatcc cctttcaagt tcttttcact tgaaccgatg ttgatgagtc
     4561 tgtcaataac acttggtgtt ttaccataaa aatcaggttt gaacatcatg atgtttttta
     4621 tacttatgtc accgtatttg atatcatagt aacgattgag ataagtcaga gccatcatga
     4681 ttttagcttt attggtttcc actttcttga gaagtgattt tatcgcagct tcatcaccat
     4741 tcaattgatg gtcttcattt tcgaccaagg atttgactaa cttatctaga ttttgcttca
     4801 cttcggcaaa gctttcttct aagtatagat ctttaatata accattctta cgttcatccg
     4861 tattctctgc aggtttatca cgtctactca ttaaatctct tacttcttgt gaaatcaatt
     4921 ccacacttga taattgagat ttaacatcag caatcaattt atcacgattt ttaacaacca
     4981 tattcggtgt ataaacaaca tcaccaagac cagatacact atattcacgc acttgttgga
     5041 ctttagaatc agtattctta gtaacatcca tttcttcctt agtaccatca gcatagtgaa
     5101 ccataatctt atcaatatct gataaatcgg tcacgaattg accatccttc atccccgtaa
     5161 cagaaaggac ttctttctta gctaagtttg aatcttctgc aagtttgtta ccttggttga
     5221 caatccattc tttattataa aatggttgaa gtttctcaat attacgataa gctaaatcac
     5281 gttcggattt gtagtcttga gttgacttat attcatcttc tcttctggtt aaacgattta
     5341 agcgattgac cacaggttcg ttgatttcgt atttatcagc agtaagtcca aaatttgcaa
     5401 ttctcttatt agcttcatct tgactaattt ctttaatttt gtcacgagaa cgtttgtatg
     5461 aatgcttacc tgaactgaca cctttgacaa caaagttacg ctctaaccag ccatttgtga
     5521 aataaccacc atcgtagtcc aaatcggaag aaccaaagaa ctcttcacca ttttcaactc
     5581 tcatcattga aatattatct tcaagtttac caaaaggaag attgctattg ataaatccac
     5641 ctgtttcaaa caaaacttta gtcttaatgg ttcctttggt gactgattta cgaattgaac
     5701 cgtatttacc aattcccata gagtcgttac cattatctgt tttagcaact aaaccaccta
     5761 tacgggctct gttagcaaca atatcagcct cgacatatgc ttttgcaaga ttacctctcc
     5821 aaatctcacc ggcaatgcca gccatatatt gacctttatc accaacacct gtaagattac
     5881 cgatgaaggc tacatttgtc aactgaccac cactatcgat tttattgacg atacccgcaa
     5941 tattgttatt agcaactaca ttaccagtta ccttaacatc ttcaacagtt gcatttttca
     6001 ccatattggc aacaggtgct attccgtcag cccaaggcat attgatatcc acattaccta
     6061 aattaatatt tttcacagaa ccattttcaa cacggtcaaa taagggacgg gcaatgttat
     6121 gaattgtata ttgtttacca tcaacacttg atagatgtcc cttaaacgta cctggaacat
     6181 attgtttgtt aggtgttggt acattcgttg cattcaaatc tgctccgatt ttaaatgtac
     6241 catttttatc agcattcatg gcatctacta actctttaaa gttataataa acgtcatcaa
     6301 cttttggaac tggtttttca atataatgaa catacttgtt acgaaccttc gttgggtctg
     6361 tatgttgaat caaatcttga gcttcggcag tgattttata aagtttctta ccttcttcag
     6421 tcacttcttc aattttatca actgctaaac gtgttacttt attatcacga ctagtaattt
     6481 ttaagtacat tttcttcaca tcttcatctg aaggtttttc agtcataaaa tcactaggtg
     6541 tttcagtacc atcgtcattt accttcacta aattagtaga tgcgatattt ttaatttcaa
     6601 cttttttcaa atccaagcga agtggtttct cttctaatgt tgcagtttct tctcccttgc
     6661 cacggtcata ggtcatagtg gtctctatct tatagtcctt gtagaatttt aaatcttcta
     6721 cctgcttatc taattgctct gaagtcaaat ctactgtttt gacaatttca tttccatctt
     6781 taattgtcgc agtaatttta ttgattgtga ctccatctgt attaactaaa tgataagaaa
     6841 gagttgcgga tcggtttaat acatttgtat ttgttctatc taaggtcaaa acaggagccg
     6901 ttttttcttt aggtttttct ttggtacctt ttacaagaat tttaggcttc atttctttca
     6961 aaatagttac tgtttcaact gggtcactga tttttttgcc atgtaactct tcatagctag
     7021 taacaatttg acgttcgcca tcctcaccaa cttgtctaac agaatcatcg cctataaatt
     7081 tgctaggatc agattcttct atagtggttt taggaatagt ctctgtccga atatcggtat
     7141 gtaaagaagg caactcttct ctttctgatg caacttctga aactgtagat attggttcag
     7201 tatactctgg aatgtcgcta acaggtggct caatcaagtt tccattttca tccactcctg
     7261 ttgtacctac tggctcagta tattctggga tgtcgttaac aggtggttca atcaagtttc
     7321 cattttcatc tactcctgtt gtccctactg gttcagtgta tgctagtttc tcatgaactt
     7381 caggctcaac aaggtttgca cctattggtt gcgtatagtc aggcttctca tgaacttccg
     7441 gttcgccttt ctctgttaca actttgggtt gctcaactgg cgaaacagtt gatgctggag
     7501 aaaccgacga aacagtttta tcatcaagct ccaagtaacc aacatatctg taaccagaaa
     7561 tttgcaacac accatcacgt ccagactcat ggatgttagc attcaaatta agtgctgaag
     7621 cagttgatag tgtaactaaa cctgtcgccc ctacaatcaa aaatgtagct atttttttat
     7681 ttctattatc ttttgtgata atcacaataa gactcccgat agctaacaaa cccaatgcag
     7741 tcataataga ttgagaactt cctgtgtttg gtagtgcgtc tttttcataa tccaaagcat
     7801 atgactcttt ggattcatca ggtctacctt gtttgagttg atcacgttca gtttgtgtca
     7861 aactactata atctaagtaa tgataagtcg atgcaccaac aactgacggt gcaaataaaa
     7921 gactccccaa gaataccgaa ccaacaatac cctttatttt ccgaatggaa aatttatctt
     7981 tttttaataa tgacaattct aatcctccac cttcactttt tatttcctaa tagtaaacac
     8041 tattttttat tctcaaaaat tgaacttcta aaatcaccgg tttggtcaag ataagcttta
     8101 aagattgctt ttttcagttt aagaactcta ctatttgtct caggatataa tttggcaact
     8161 tcatcctcag catcaaattt tactgcatct tcaatcattt tttcaagtct attaatatta
     8221 tcaatagtca ctttctgttg tcgagcccaa gaaccgtttg gatcgataaa actaacttta
     8281 tttaactttc caaatttatc ttctctttct ttatacatat ctttcttgaa atctatccaa
     8341 gaattatact ggttattaaa tacttttgaa agaacaattt catcagtaac taaacctatt
     8401 tgtttaccat atgatgtaat aacttttcct tgagctttcg cttctttttc atactgatta
     8461 gaaatatatg gaaccatacc gtctttgtac cccttggctg ccaataactc aaatgcaata
     8521 cgtcgtccca ttaaatctcc tggtgttcct attttactgc tcaatgctga ataaattggt
     8581 gagaatagat taattgtata gtagccattc cgcttataag ttgcttcatc tacataacct
     8641 cttcttgtta taatatcatg ttctatcaaa ctgttaaatg tagttaattt agtaagttct
     8701 tctggtttta atctacgtac aacattcgtt gcataaacag aatttccatc aggatcaggt
     8761 ttatattcat tttctatttt tcttaataaa tcatattttt gatttgtatc taatttagct
     8821 acagctttac cttctagtat ttcaagcatg tatattacat caaacatatt atgcatatac
     8881 ttatttagat catcaacact tccaaatcgt tgagttggat ctgctacttg aagccttgtt
     8941 gattcttctg attgatcata ttttaatatg gaattaatag tgactgttgg atcattagga
     9001 tgatcaggag cttgtagcag tcctttagca taaaactctg gtccaagtcc atttcgtctt
     9061 ccatagcctc caagataaat ttctctatct gagttatgtg tcatttcgtg tgtataagtt
     9121 accgcaccat ctttatcaag catgcgatat gccatataat agaatgcatc ccctgtagca
     9181 tatgctccat tagaattatg aacaacatta tttcccgctg gaccgaagaa atgttttata
     9241 gctggatgat tagtttcaaa agttgcttga tatgtatctt tatcttcttt ttcatctgta
     9301 ccaaatctaa atgcatcata gactagaaca cttctatata atttttcttt atttttatca
     9361 tctagtattc tataccaata atcatagtga tctctaaatc taacagccgc ttctttagct
     9421 tttttctcaa catagtcatt taaatcagtt cctgctggat gttctttact tctatatcta
     9481 tcataagcac cgaaacctat agtcgaaatg ttggctataa taaacaccga tttttcaggt
     9541 aatgttaata gcggcaacac catacttgga tatttccaag atgggctagt taatctatca
     9601 tatactccaa ttgaatatgg actaccagct attgattgct tatcacttac ctctttaata
     9661 gtagattttt cttctacaat atatgcttta gtttgttctt taaaccactc attatttgtt
     9721 ttatctggta caaatgcttt tctatatttc tctaatgcat caaataaatt attagtctta
     9781 taatttttcg ctaataaaac attataagtt ataacattat tttttgctag taagttatta
     9841 tatcccgatt tacctagttc gataacatta tctaacgctg aactatttga tttaccgaag
     9901 aaatccaagt ggtacatgac taaatctttc gcttttgtat cacgatattt gaagtcgtac
     9961 caacgctcta agtatgttaa tcctagaagt aaagcttctt tattattttt aattttctcg
    10021 attacataat tatctattac cttattgtta ttttcagcta ttgcagcatc tgcagtaaga
    10081 agttttgtca aactatcttt caaattagtt tttgtggtat tgaattgttc ttctaaatat
    10141 aactccgtta aactaacatc cttagaaaca tctaatactt ttctaattgc ctctgattta
    10201 tattctacac tatttaatgc tggtaatact tcatctaaaa tattttgata attgcgaagt
    10261 aatgtattcg gtgtataaat taagtttgta ccgcctattc tatactctgc tacatttgaa
    10321 aaatcagttt gataatttac attaagtgtc tctgatgtat tatccgcgta atatagtaat
    10381 agtttattta tacttgattt atttttgtta atatcactaa ttacttcttt atctttcata
    10441 gggactactg acaataattc tttattataa agattactac ttgtctctac taaatttccg
    10501 tacttaacaa ttgtttctct attataaaac ggtaatagtt tttcaatatt tttatatact
    10561 ttttcttttg atgaatcagc attctcaaga tttttatagt cagttacata tctagaagag
    10621 aaattaaaat cttctgtttt aatagtattt ttagatacaa aagtagcttt tttctctttt
    10681 atttgtgcat cttctaatac ttctcctctt tgaacagtag aatccttagt taagatttca
    10741 tcatcttctt gtactacgtt cacaacctta ttatttttat tactgtatgt gccatttgct
    10801 tttataccat taaaattata acctgcaata gcattaccat tcgttacatt aacatcgctt
    10861 agtacattag aaagtcgacc ggatttttct aatcctccaa ccggatccca aagattacca
    10921 actactccac caacgtttgc aaaacgttga acattattta gatttccttc agcataacta
    10981 ttactaataa gcgcactatt ttctactgca ccaactattc caccaataga ctggtctcct
    11041 tgtgttgcat ttgaagataa atcgattgat gcgaacgact tatctattaa tcccctcgga
    11101 ccagaaagtt tgcctactaa acctccgatt tgataactag caactgtttt atatgtatta
    11161 gttattctac ctgtatagct actgttagaa atagtagaat tattaacttg tgatactaat
    11221 cctcctatgc tacgttcccc agctatcgct ccatcagcat gaacgttatc aatatgagta
    11281 ttgttatttg cttctttcgc aagtgttgca gtatcgtcct ttgcggaaat attaacatct
    11341 tttagtgaaa gtttttctac tgtagcacca tttaattccc caaataatgg ttttttcaaa
    11401 ttataaatag cataatattt ctcattattt gttcctacta atattccatg gaatacatta
    11461 ttcacataac tttcttgacc atctggaagt tcaacttcac gagcatccat agttgctcct
    11521 aaacggaatg tgccattagg attgctattc attgcatcta ctaaattttt aaatgatgta
    11581 tataccccag tttcactttg ctgagttttt ggtaaatagt atgtataatt ttctagtaca
    11641 ttattatttt catgttgtat cagactattt gcacttgcta ctatcttata aacatctcta
    11701 ttatctttag tatcattagt aatgcttgta actggtagca tcacatcttt aaagttctct
    11761 gatttaactt tcataaagta attttctgca ttacttggta aagaagcaag tgaagttaca
    11821 tgtcgatact tattaccatc ttttgaatat agttctacag aagatatatt tctaagttct
    11881 aatttcttaa taacttcttt ttcatcttta gcgtcatctt ttttctcatc tttatgacga
    11941 taaagttcat cgtatactgg tggaatttca ttacctgcta taatactctt aatccaagct
    12001 aattgtgtag gagataaaat caatccgcct gagcgatttt gtgctccatt ttgatgcaca
    12061 ccaataactt caccattagc attaaatatt cctccaccac tcataccagg atttccacct
    12121 tgatattgaa caccgtaggt gttattcgca tattcttgtt ccatttctac cgtagcatct
    12181 tttaagtgcg tatatttccc agctggatat ccatgaacat ttagtttgtc attaagattt
    12241 actttcgaat aatttttaac taattctaca tgttctctgc cagttgtttc aggtagctta
    12301 atcactgcta aatcatagat aaatcctttt ggataatctt ttttattata aaaatgaata
    12361 ttgttagcag taaatgttcc tttttgtcca tcaggagtca cccactcata tacgttttta
    12421 gatttatcac ctctaaattc gccagtagta ttatcagtag aattattaat gaaattatgt
    12481 gctactgtta aaagtacatt tggtgcaata aaagtagctg atcctactcc agtaaccttc
    12541 gacgaatctg taataaagtt catattaatt aatgcactag attttttctg aatactcatt
    12601 tcttctggtg tattagtatt ttcattattt ggtttagtat cttctgcact aggttgttcg
    12661 attttaccag tatattcttt cagtgcttct actttttctg gttctactat tgctccggct
    12721 tgcactcctg tgtattcctt cggtgcttct accttctctg gttcgactat cgctccagcc
    12781 tgcactcctg tgtattcctt cggtgcttct actttctctg gctcgactat cgctccggct
    12841 tgcacccctg tgtattctgg tagtggtgct acctgctctg gttcaacaat agcgccagct
    12901 tgtactccag catattccgg ttcaactttt tcaggttcaa caatagctcc agcttgtact
    12961 cctgtatatt ctggtagcgg ttctacctgc tctggatcac ccttgtcagt catgactgcc
    13021 tctggtaacg ctggttgaac ttctggtacg cctttatcac ttactacagc ttctggcaac
    13081 tctggttgga ctgctgactc acctttgtcg gttaatacag ctgctggtag ttcaggctga
    13141 attgcgggtt caacaatagc tccagactgt acttccttat gttctgcacc agtctcagct
    13201 tgttccttta taacttgagc ttttttagta cctttttcga ctattcttga aacaggcgca
    13261 gtcgttgaag ttgaaataat ttctcgtgaa acttcttcat tgtttacaga aaatattctg
    13321 acgatttcaa ctttcttacc taatgcacct tcttgtttta ctcttacagt tccttctgct
    13381 aaatcaggat tttcttgaat ttcttcttga aaatctattt ttgtttctat agtttcgtca
    13441 cgatataaga gttccggttt gttcaactga cctgatagca cttcatcctg tggatttaat
    13501 gtatttaccc cagtcttttc ctttggagaa atcttctcct ctttcttcgt ttctagattc
    13561 ttatgttcgg ctaattgttc ttgagaatct gaagattgtt tctcttcttt tcttggattg
    13621 attaattcag tagagaaagg tttttcaact acttgaactt ctgtcggctt agttgaagaa
    13681 acaggtgttt gttcctgaat agcttgtact gttgatggat ggtctacaaa atttggtgta
    13741 acattataat ccaccttttg ttgttttgta ggagtggctg ctgatttttc ttgattactt
    13801 acttcaaaat cagaagtcgt ttttccctct ttgatatatc caatataagt gtaacctgaa
    13861 atctctttag gaagaggtaa tttttctcca gaggtcaatt catagtccgt attgtaattt
    13921 agcaaaagat gattttctaa agcatggact gaaactaaga caccatttcc cattcccgca
    13981 accaatacta aatgtaatac cgttttattc ttaacctttt tcttggaaac agcaaaaatt
    14041 aaaattccca gagcagctaa gctagcacca gaaactaggg cttgcctctc attcttgctt
    14101 ccagtatttg gtaattccgc cagttgattt tgagaattta acttataaac aagataataa
    14161 gtttcatcat cattctccac gtatgtcgga atatcataga caagctgctt cttttcttct
    14221 gatgatagct ctgaatctgc cacatattta tagtgaactc ccgcagtttc ttgagcatcc
    14281 acagatgaac tagctaatac agacataaaa aataaacttg aaatcgttgc agatacaagt
    14341 cctactgata attttctaaa tgaaaaacgc tcttgttttt caccaaaata cttttccatt
    14401 attcctcctt gaaataaaat ttatatatgt tacaaagacc tttattatat tagtgtatta
    14461 tctattatct atagaaaagg cagtatacct taattatact cttaatttac aaaaaagtct
    14521 taaaattgag atgcgctttc atactttgtt ttatattatt tgggggtaca ataacaccta
    14581 ccatgaaatt tacacggtag gtgttactca tatcactaat cgttctaaaa atggtttgag
    14641 gcagttgagg agaattcctt ctatccagct tccttgtgct gatgagcgat ggtcttcctg
    14701 caggcttttt tttagaaaat ctcggacttg ttctggtgcg atttcaaatt caaaggcttt
    14761 cattttatag aaaaagtcga tgagatgatc ggacaggtat tcagttgaaa agggtacttc
    14821 accacttttt cgatattcta ataagagcct agaaaatcga gctttttctt caggaagctc
    14881 acgaaaatag gaattgagga gccaagtctg cttctgtttt ctttcaattg gatcctgact
    14941 ggcaattcgt tggtcttttt ccagctcttt ttggtattgt ttggccttga tagcccgttc
    15001 tgctctattt ttaccaaaaa gaattttttc ccacttgcgt tcttcttgag tcagggtctc
    15061 tgtaaagcca aagtaatctt gataagcacg ctctgcgggt cccatggcta gaaccagatt
    15121 gtctgcatat tgcttggcga ttttatccct cttcttgcgt tctttctctg cctggatacg
    15181 gagttcttgt tcgtagtcaa ttttctcctt gcctagcttg acaaggtaga gttggtcatc
    15241 cgatttccca agtaaaaagg gtttgataca cttttcaagg acttcttcca tccgagcctt
    15301 tttctttggt tccgccttgg tccaacttcc tccctgaaag acttctagga aaagctggta
    15361 gtctctctca ggcgcaaatt gattgccacg attgggtttg aaaacacctt tttcccagag
    15421 ccattttaga agtcgctcgt caaagtcact tttattgacc ttgatttttt cttttttctg
    15481 agcttttctg gttagatttt caacctttct gagcagtttt tcttcctctt ccaattgctg
    15541 gtcaagggac aatcgatgaa aatgacgaac acagtcgcta ccaattggaa agaggcgttg
    15601 gcctgtgaca ccgttaaaga gttcataagc gtatttgatg gcatttccac agacacaatt
    15661 gctacggccg ataccgttaa aaatcaagga aacttcattc cattccttgg tagcttgttc
    15721 ccaagtatcc gctttcgaag cctgtaaaac tgcatcgtgc agggattttc taactggaag
    15781 tgtcatgagg tctcctttct aatactcaat aaaaatcaaa gagcaaacta gaaagctagc
    15841 cgca
//
LOCUS       DAVBOG010000048        14743 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.048, whole genome shotgun sequence.
ACCESSION   DAVBOG010000048 DAVBOG010000000
VERSION     DAVBOG010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14743)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14743)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14743
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.048"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            83..880
                     /locus_tag="VQ865_001707"
     CDS             83..880
                     /locus_tag="VQ865_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000254803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HET3136017.1"
                     /translation="MVSSEFISKIEFACNKKESLYSQSKFKYAIRSMFAGAFLTFSTA
                     AGAVGADLINKIAPGSGRFLFPFVFAWGLAYIVFLNAELVTSNMMFLTAGSFLKKISW
                     RKTAEILLYCTLFNLIGALIAGWGFAHSAAYANLTHDSFISGVVEMKLGRSNELVLLE
                     AILANIFVNIAILSFILVKDGGAKLWLVLSAIYMFVFLTNEHIAANFASFAIVKFSVA
                     ADSIANFGVGNMLRHWGVTFIGNFIGGGFLMGLPYAFLNKNEDTYVD"
     gene            1028..2287
                     /locus_tag="VQ865_001708"
                     /pseudo
     CDS             1028..2287
                     /locus_tag="VQ865_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015604466.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylhomoserine
                     aminocarboxypropyltransferase/cysteine synthase"
     gene            2383..3657
                     /locus_tag="VQ865_001709"
     CDS             2383..3657
                     /locus_tag="VQ865_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001002592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2130 domain-containing protein"
                     /protein_id="HET3136018.1"
                     /translation="MNEIKCPNCGEVFTVNESQYAELLSQVRTAEFDKELHDRMRQEL
                     ALAEQKAMNEQQTKLAQKDQEIAQLQSQIQNFDTEKELAKKEVEQTSHQALLAKDKEV
                     QALENQLATLRLEHENQLQKTLSDLEKERNQVKNQLLLQEKENELSLASVKQNYEAQL
                     KAASEQVEFYKNFKAQQSTKAIGESLEQYAESEFNKVRSFAFPNAYFEKDNKVSSRGS
                     KGDFIFRECDENGVEIISIMFEMKNEADGTEKKHKNADFYKELDKDRREKNCEYAVLV
                     TMLEADNDYFNTGIVDVSHEYEKMYVVRPQFFIQLIGLLRNAALNSLKYKQELALVRE
                     QNIDITHFEEDLDAFKLAFAKNYNSASTNFGKAIDEIDKAIKRMEEVKKFLTTSENQL
                     RLANNKLEDVSVKKLTRKNPTMKAKFEALKGE"
     gene            3667..4545
                     /gene="truB"
                     /locus_tag="VQ865_001710"
     CDS             3667..4545
                     /gene="truB"
                     /locus_tag="VQ865_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007516878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HET3136019.1"
                     /translation="MNGIINLKKEAGMTSHDAVFKLRKILGTKKIGHGGTLDPDVVGV
                     LPIAVGKATRMAEFMQDEGKIYEGEITLGYSTTTEDASGEVIAETPVLSPLDEKLVDE
                     AIASLTGPITQIPPMYSAVKVNGRKLYEYARAGQEVERPERQVTIYQFERTSPISYDG
                     QLARFTFRVKCSKGTYIRTLSVDLGEKLGYAAHMSHLTRTSAAGLQLEDALALEEIAE
                     KVEAGQLDFLHPLEIGTGDLVKVFLTPEEATEVRFGRFIELDQTDKELAAFEDDKLLA
                     ILEKRGNLYKPRKVFS"
     gene            4786..5088
                     /locus_tag="VQ865_001711"
     CDS             4786..5088
                     /locus_tag="VQ865_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000985087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HET3136020.1"
                     /translation="MMRNEFRERVEQLLQQKEINENSELSHLFRLAIQNLDRNEKYQT
                     VMANLSQGLSLYLMTHHYQAPKSVIDFGLWIAKAPSQERGRLAFLQMLAQTLQGFR"
     gene            5196..5834
                     /gene="udk"
                     /locus_tag="VQ865_001712"
     CDS             5196..5834
                     /gene="udk"
                     /locus_tag="VQ865_001712"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001181378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HET3136021.1"
                     /translation="MQNRPIIIGVTGGSGGGKTSVSRAILSHFPDEKISMIEHDSYYK
                     DQSHLTFEERVKTNYDHPFAFDTDLMIEQIKELLAGRPVDIPTYDYTEHTRSSKTYRQ
                     EPQDVFIVEGILVLEDKRLRDLMDIKIFVDTDDDVRIIRRIKRDMEERGRSLDSVINQ
                     YLGVVKPMYHQFIESTKRYADIVIPEGVSNTVAIDLLTTKIAKILEEARNSK"
     gene            5962..7302
                     /locus_tag="VQ865_001713"
     CDS             5962..7302
                     /locus_tag="VQ865_001713"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000417449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HET3136022.1"
                     /translation="MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQY
                     FSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDG
                     VGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRF
                     PGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVV
                     RAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEK
                     RMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDN
                     KQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLM
                     LDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI"
     gene            7280..7492
                     /locus_tag="VQ865_001714"
     CDS             7280..7492
                     /locus_tag="VQ865_001714"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HET3136023.1"
                     /translation="MSKQKKFEENLAELETIVQSLENGEIALEDAITAFQKGMVLSKE
                     LQATLDKAEKTLVKVMQEDGTESDFE"
     gene            7489..8364
                     /locus_tag="VQ865_001715"
     CDS             7489..8364
                     /locus_tag="VQ865_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000743807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HET3136024.1"
                     /translation="MKKQEKLALVESALEDFYGDQQFASSLRESVLYSIHAGGKRIRP
                     FLLLEVLEALQVAIKPAHAQVATALEMIHTGSLIHDDLPAMDDDDYRRGRLTNHKKFG
                     EAMAILAGDALFLDPYALIAQADLPSQIKVDLIANLSLASGSLGMVAGQVLDMEGEHQ
                     HLSLEELQTIHANKTGKLLAYPFQAAAIIAELSPEMQVKLKTVGELIGLAFQVRDDVL
                     DVTASFEEIGKTPQKDLQAEKSTYPALLGLEESIAFCNQTLDQANEKLEEIAQQVPFE
                     TESIVSVVESLRING"
     gene            8357..9172
                     /locus_tag="VQ865_001716"
     CDS             8357..9172
                     /locus_tag="VQ865_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HET3136025.1"
                     /translation="MAKERVDVLAYKQGLFETREQAKRGVMAGLVVAVLNGERFDKPG
                     EKIPDDTELKLKGEKLKYVSRGGLKLEKALQVFDLSVDGATTIDIGASTGGFTDVMLQ
                     NSAKLVFAVDVGTNQLAWKLRQDPRVVSMEQFNFRYAEKTDFEQEPSFASIDVSFISL
                     SLILPALHRVLADQGQVVALVKPQFEAGREQIGKNGIIRDAKVHQNVLESVTAMAVEV
                     GFSVLGLDFSPIQGGHGNIEFLAYLKKEKSASNQILAEIKEAVERAHSQFKNE"
     gene            9165..9596
                     /locus_tag="VQ865_001717"
     CDS             9165..9596
                     /locus_tag="VQ865_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001034407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3136026.1"
                     /translation="MNKKERLEKIRRLVTDYQIGTQEEIVEHLKEAGITATQATVSRD
                     IKELGIVKIPLRDNTYVYELPKSIVKSLQLAEDNIESAELMDKMINLQVIPGNTAFVK
                     AQLIETFADKIFSCLTDDSSILVIARSGSLAEEIFEQVKNW"
     gene            9603..11270
                     /gene="recN"
                     /locus_tag="VQ865_001718"
     CDS             9603..11270
                     /gene="recN"
                     /locus_tag="VQ865_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HET3136027.1"
                     /translation="MLLEISIKNFAIIEAISLNFEKGMTVLTGETGAGKSIIIDAMNM
                     MLGARATTDVIRHGAPKAEIEGLFSVENSRLLQEIFDEQGLELGDEIIIRREILQNGR
                     SISRVNGQMVNLSVLRAIGQHLVDIHGQHDHEELMRPQLHIQMLDEFGDAAFWDLKET
                     YQTSFDAYRKMRKQVLEVKKNQQEHKARIEMLEFQMAEIEAANLQAGEDLALNQERDK
                     LLNHKNIADTLTNAYSMLDNEDFSSLANVRSAMNDMESVEEYDPEYREISSSLSETYY
                     VLEDISKRLEAIIEDLDFDGNRLMQVENRLDLLHTITRKYGGTVDDVLLYFAKITEEY
                     NLLTGNNLSSEDMEAELKKLEVNLVNLAGQLASARHNLAQQLEAEIKQELQDLYMEKA
                     QFQVRFSKGKFSREGNEMVEFYISTNPGEDFKPLVKVASGGELSRLMLAIKSAFSRKE
                     GKTSIVFDEVDTGVSGRVAQAIAQKIHKIGQYGQVLAISHLPQVIAIADYQFFIEKIS
                     NDHSTVSTVRLLTVEERVEEVAKMLAGDDVTEAALTQARELLRNREK"
     gene            11272..12000
                     /locus_tag="VQ865_001719"
     CDS             11272..12000
                     /locus_tag="VQ865_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HET3136028.1"
                     /translation="MTDYYVIGDVHGKAGMLEDLLKTWDGQTQLLFLGDLIDRGEDSH
                     RVLEMVKDLVDNQGAICLSGNHEYMFLTWLDDPEESYDHYRRNCGDTTINSILGRPLD
                     APVDGVEDAKRVAAEAADLVEFIRQMPFVVETDKYIFVHAGIDLTLDDWHETTDYKKV
                     WLRKPFHGAENHTGKTIVFGHTPVYGLLQQERGTSELWTTEDGKIGMDGGAVYGGVLH
                     GIVFTDQGMTEHHFIENDGFVAED"
     gene            12079..13902
                     /gene="lepA"
                     /locus_tag="VQ865_001720"
     CDS             12079..13902
                     /gene="lepA"
                     /locus_tag="VQ865_001720"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001047203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HET3136029.1"
                     /translation="MNLEELKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMELERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAILVVDAAQGIEAQTLANVYLALDNDLEIMPIINKIDLPAADPERVRTEIEDVI
                     GLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVTAPLKALIFDSVYDAYRGVILQ
                     VRVMDGVVKPGDKIQLMSNSKTFDVAEVGIFTPKAVGRDFLATGDVGYIAASIKTVQD
                     TRVGDTVTLATNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQ
                     FEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVIYKVNLTDGESMD
                     VSNPSEFPDPTKIATIEEPYVKAQIMVPQEFVGAVMELAQRKRGDFVTMDYIDDNRVN
                     VIYQIPLAEIVFDFFDKLKSSTRGYASFDYELSEYRPSKLVKMDILLNGDKVDALSFI
                     VHKDFAYERGKLIVDKLKKIIPRQQFEVPIQAAIGHKIVARTDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEE"
     gene            complement(14106..14186)
                     /locus_tag="VQ865_001721"
                     /pseudo
     CDS             complement(14106..14186)
                     /locus_tag="VQ865_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            14360..>14743
                     /locus_tag="VQ865_001722"
     CDS             14360..>14743
                     /locus_tag="VQ865_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3136030.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEQLFDQVASLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKDLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPGK
                     EVEVSLLFFIINNSSSSQTNILAQLM"
BASE COUNT         4389 a         2669 c         3480 g         4205 t
ORIGIN      
        1 acttttatga aatacagaaa acgcttccta aaacctaaag tttgtgatat aattatcaag
       61 aaaaaagatt taggagttta ttatggtttc ttcagaattt atctcaaaga ttgaatttgc
      121 ttgcaataag aaagaaagtc tttatagtca aagcaaattt aagtatgcga ttcgttcgat
      181 gttcgcaggt gcatttttaa ccttcagtac tgctgcaggt gcagttgggg ctgacttgat
      241 taataaaatt gcaccaggta gtggacgctt cctctttcca ttcgtttttg cttggggctt
      301 ggcctacatt gtttttttga atgccgagtt ggtcacttca aacatgatgt tcttgactgc
      361 tggtagtttc ttaaaaaaaa tctcttggag aaaaacagct gagattttac tatactgtac
      421 cttgttcaac cttatcggag ccttgatagc agggtggggc tttgctcatt cggcagccta
      481 tgcgaatctg acacacgata gtttcatctc aggtgttgtt gagatgaagt taggccgctc
      541 aaatgaattg gtcttgcttg aggcgatttt ggcaaatatt ttcgtaaata ttgcgattct
      601 gtcatttatt ttggtcaaag atggtggtgc caaactttgg cttgtgttgt cagctattta
      661 catgtttgta ttcttaacaa acgagcacat tgcggcgaac tttgcttctt tcgcgattgt
      721 gaaattcagt gttgctgcgg attcaattgc caacttcggt gttggaaata tgcttcgcca
      781 ctggggtgtg actttcatcg gaaactttat cggaggaggc ttcttgatgg gtcttccata
      841 tgccttcctc aataaaaacg aagatactta tgtagattaa gaaaatgagc acgattgagt
      901 cgtgcttttt tcattttcaa aataaggtaa tagctatttc ttatatcaaa atatagaaaa
      961 ctgatatttg taaactataa ctcaaggtgc tacaatatcc ttaataaaat gatatggagg
     1021 tcaccttatg acttgtgatt ttaaatctga aactctacaa ctacatgctg gtcaagttgt
     1081 ggctccagct actaagtctc gtgcagtgcc gatttatcaa acaacatttt ttgtttttga
     1141 tgacacgtag gaaggtgccg atctgtttgc cttgaggaaa ccagggaaca tttatactcg
     1201 tatcaccaat cctacaacag ctgcccttga aggtggtgtt gaagcgctag caacagcatc
     1261 aggtatgact gcagtgactt atacgatttt ggcgcttgcc catgctggtg accatgtagt
     1321 ggctgcttcg actatttacg gtggaacctt caatcttttg aaagaacccc ttcctcgtta
     1381 tggtatcaca acaacctttg tcgatgttga taatttggag gaagtagaag cagttatcaa
     1441 agacaatacc aagcttgtct tgattgaaac cttgggtaac tccttgatta atattccaga
     1501 cctggaaaaa ctggcagaga ttgctcataa acatcaaatc ccacttgtgt cagacaatac
     1561 ttttgcaata ccttatttga ttaacgtctt ctctcatggc gttgacattg ccattcactc
     1621 tgcgactaag tttatcggtg ggcatggtac aactattgga ggaataattg tcgatagtgg
     1681 tcgttttgac tggatggctt cagggaaatt ccctcaattt gttgacgagg gttcaagctg
     1741 ccacaatttg agctatactc gtgatgtggg tgcagtagcc tttattatag ctgttcgagt
     1801 tcaattgctt tgtgatacag gtgcagcctt gtcaccattc aatgctttcc tcttgctaca
     1861 aagacttgaa accctttcac ttcgtgtgga acgccatgta caaaatgctg agacaattgt
     1921 tgattttctt gtcaaccatc ctaaggtaga aaaggtaaat tatccaaaac ttgcagatag
     1981 tccttatcat gcattggctg agaaatactt gccaaaaggt gtcggttcaa tctttacctt
     2041 ccacgtcaaa ggtgacgagg aagaagcacg caaggccatt gataatttag aaatcttttc
     2101 tgaccttgca aacgcggcag atgctaaatc gcttgttgtc catccagcaa caatcactca
     2161 cggtcaattg tcagaaaaag acctagaagc agcaggtgtc acaccaaatc aaatccactt
     2221 gtctatcggt cttgaaaatg tagaagattt gattgaagac ttacgcttag ccttggaaaa
     2281 aatttaaagt aaaagaagat aaacagtggg ttttgactca ctgtttttga ttttccctca
     2341 ggcatgatat aatggttaca gaagtctaga aagaggaatg taatgaacga aatcaaatgt
     2401 cccaactgtg gggaagtctt tacagtaaat gaaagccagt atgctgaact tttgtcccaa
     2461 gtgagaacgg cagagtttga taaggaacta cacgatagga tgaggcagga actggccttg
     2521 gctgagcaaa aggctatgaa tgagcaacag actaaactgg ctcagaagga tcaagaaatt
     2581 gcgcaattgc agagtcaaat ccaaaacttt gatacagaaa aagaattggc caagaaagaa
     2641 gttgaacaga caagccatca ggccttattg gctaaggaca aggaagtaca ggccttggaa
     2701 aaccagttgg cgaccttgcg tttggagcat gaaaatcaat tgcaaaagac cctttctgac
     2761 ctagaaaaag aacgcaatca ggtcaaaaat cagctcctac tgcaagaaaa ggaaaatgag
     2821 ttgtctttgg cttctgttaa gcaaaactac gaagcccagc tcaaagcagc cagtgaacaa
     2881 gtcgagtttt ataagaattt taaggctcaa caatctacaa aagcgattgg ggaaagccta
     2941 gaacagtatg cagagagtga gtttaacaag gttcgtagtt tcgcctttcc aaatgcttac
     3001 tttgagaagg ataacaaggt ctcttcgcgt gggtctaaag gggactttat cttccgtgag
     3061 tgtgatgaaa atggagttga aatcatttct atcatgtttg agatgaaaaa tgaagcggac
     3121 ggaacagaga agaagcacaa gaatgcagat ttttacaagg aattggacaa ggaccgtcgg
     3181 gagaagaact gtgagtatgc cgttttggtg accatgcttg aggctgataa tgactacttt
     3241 aacacaggga ttgttgacgt cagtcacgag tatgaaaaaa tgtatgttgt tcgtcctcaa
     3301 ttctttatcc aattgattgg tctcttacgt aatgcggcgc taaattccct aaaatacaag
     3361 caggagttgg ccttggttcg cgagcaaaat attgacatta cgcattttga ggaagatttg
     3421 gatgccttta agctagcttt tgctaagaac tataattcag cttcgactaa ctttggaaaa
     3481 gctattgatg aaatcgacaa ggccatcaaa cgcatggaag aggttaagaa attcctgact
     3541 acatctgaaa accaactccg tctagctaac aacaaattgg aagatgtctc tgttaaaaaa
     3601 ttgacccgga aaaatccaac aatgaaagcg aagttcgaag cactgaaggg ggagtagaaa
     3661 gcaaaaatga acggtattat caacttaaaa aaagaagcag gaatgacctc gcatgatgcg
     3721 gtttttaaac tgcgtaagat tttgggaacc aagaaaattg gtcatggtgg aaccttggat
     3781 ccggatgtgg tgggtgtttt gccgattgcg gttggcaagg cgacacgcat ggccgagttt
     3841 atgcaggacg agggtaagat ctatgagggg gaaattactc tgggttattc cacgacgact
     3901 gaggatgcta gtggggaagt gatcgcagaa acccctgttt tgtctccctt ggatgaaaag
     3961 cttgttgatg aagcgattgc tagcttgact gggcctatta cccagattcc ccctatgtat
     4021 tcggcagtta aggttaatgg tcgcaagctc tatgagtatg cgcgtgctgg tcaggaagtg
     4081 gagcgtccag aacgtcaggt gaccatttat caatttgagc gaacaagtcc gatttcttat
     4141 gatggccaac ttgcccgatt cacttttcgt gtaaaatgca gtaaagggac ttacatccgt
     4201 actttgtcag ttgatttggg tgaaaagctt ggttatgcgg ctcatatgtc ccatttgact
     4261 cgtactagtg ctgctggctt acaattagaa gacgctcttg ccttggagga aattgctgaa
     4321 aaagtagagg ctgggcaatt agattttctc catcctttag agattgggac aggtgacctt
     4381 gtcaaagttt tcctaactcc agaagaggct acagaagttc gctttggtcg ttttattgag
     4441 ctagaccaaa cggacaaaga actggctgcc tttgaagatg ataaattgtt agccattcta
     4501 gaaaaacggg gcaatctcta taagccaagg aaggttttta gctagatcgt ttaggaataa
     4561 aaatcgggtg atagataaca attgcttgct aaaaccccat actaatagta gaatggtttt
     4621 gggaattata atattccaat tgttgcgagt tgtaggtact caaataatct atatagaaat
     4681 ttagaggtgt gaaatgaagc aatttaaaat tctttcagat aaatatttag agtccattac
     4741 aggttctggt gggaacttag gcccagaatt tggtgtgata attccatgat gcgaaatgag
     4801 tttcgagaaa gggtggagca acttcttcaa caaaaagaaa taaatgaaaa tagtgagttg
     4861 agtcacctgt ttcgtcttgc tatacaaaat ttagacagaa atgaaaaata ccaaacggtc
     4921 atggccaatt tgagtcaagg gttgtcactt tacctcatga cgcatcatta ccaggcacct
     4981 aagtctgtca ttgattttgg tttatggatt gccaaagctc ctagccagga aagagggaga
     5041 ctggctttct tgcagatgct tgctcaaacc ctacagggct ttcgttaaaa ctgtcgaaca
     5101 tcagagggaa gactctggtg ttttttgctg atgagactat aaattttgta aaaaatgtga
     5161 tagaatagac gacggataaa ataacggagg atagcatgca aaatagacca atcattattg
     5221 gagtgacagg tggttctggt ggtggtaaaa ccagtgtttc aagagccatt ttatcgcatt
     5281 ttcctgatga aaagatttcc atgattgagc atgattcata ctacaaggat cagtctcatt
     5341 tgacctttga agagcgtgtc aaaaccaact atgaccatcc ttttgccttt gatacagact
     5401 tgatgatcga gcagattaag gaattgttgg cagggcgtcc ggtggacatc ccgacctacg
     5461 actatacaga gcatacacgg agtagcaaga cctatcgtca ggagcctcaa gatgtcttta
     5521 tcgttgaggg cattttggtc ttggaggaca agcgtctgcg cgatttgatg gatatcaaga
     5581 tttttgtgga tacggatgac gatgtgcgca ttattcgtcg tatcaagcgt gatatggagg
     5641 agcgtggccg tagccttgat agcgttatta accagtactt aggtgtggtc aaaccaatgt
     5701 accaccagtt tatcgagtca actaagcgtt atgctgatat cgtcattcct gaaggggtta
     5761 gcaataccgt ggctatcgac ctgttgacga ccaagattgc aaagattttg gaagaagctc
     5821 gaaacagcaa ataatcacat gtggaggcct tgcctccttt ttctattttt ccctcataat
     5881 ggtacataaa tggagatttt taggcatatt tttggtataa taatacccat gaaagagcaa
     5941 gtaaatgaat agtaggtgga gatggaaaag tatttatcgg taacaacttt gaccaagtat
     6001 ctgaaaatga aattcgataa agacccatac ttggaacggg tctatttaac tggtcaagtt
     6061 tccaactttc gtaaacgacc tactcaccaa tatttctccc taaaggatga ccatgcagtt
     6121 attcaagcga ccatctggtc tgggatttat cagaaattag ggtttgacct ggaagaagga
     6181 atgaagatca atgtgattgg gcgtgtacag gtttatgaac caagtggtag ctactccatc
     6241 atcattgaaa aagctgagcc tgatggggtt ggggcgcttg cgattcagtt tgaacaactt
     6301 aagaaaaaat tgacagaaga aggcctgttt caagaacgct tcaagcaagc tctgccccaa
     6361 ttttctaaga gaattggggt agtaaccagc cgtagtggag ccgttattcg agatattatc
     6421 acgaccgtca gcaggcgatt cccaggtgtt gacatccttc tttatccgac caaggttcaa
     6481 ggtgaagggg ctgcggagga aattgctaga aatattgcgc gtgctaatca acgggacgat
     6541 ttggatttgc tcattattgg tcgtggaggt ggttctattg aggatctctg ggcctttaac
     6601 gaagaaattg tggtacgagc tatttttgaa tctcgtttgc cagttatctc tagtgtgggg
     6661 catgaaacgg atgtgacctt ggcagatttt gtggcagatc gacgcgctgc aacgccaaca
     6721 gcggcggctg aactggcaac acctgtgacc aagttggatg tattagctca tttgcaaaat
     6781 caggaaaaac ggatggtaac ggcagtccga aatgttctat ctaagaaaca agaggctttg
     6841 aaaaaatgca gtcagtctgt tatctttaga caacctgagc gcttgtatga cggttatttg
     6901 caacgcttgg accaactgca actgcgtttg aaacaaagtt tgcgaactcg gatttctgat
     6961 aacaaacaat tagttcaagc aagaactcat caattagtac aattatcacc tgttaccaaa
     7021 atccaacgct atcaagaccg tttaggacag ttggacaagc tcttaggtag ccaaatggcg
     7081 ttagtttatg acgccaaggt tgctgaggcc aagcgacttt cggaagcttt gctcatgttg
     7141 gatactagcc gaatcgtggc gcgtggttat gctattgtca aaaaagaaga gtccgttgta
     7201 gattcggttg agagtttgaa gaaaaaagac caagtaacgc ttttgatgcg agatggtcaa
     7261 gtagaattag aggttaaaga tgtcaaaaca aaagaaattt gaggaaaatc tagcagaact
     7321 ggaaaccatt gtccaaagtt tggaaaatgg tgaaattgct ctggaagatg cgattactgc
     7381 ctttcaaaag ggcatggtct tgtcaaaaga gctccaagct acgctggaca aggctgaaaa
     7441 gaccttggtc aaggtcatgc aagaagacgg aacagaaagt gattttgaat gaaaaagcaa
     7501 gaaaaattag ctcttgtcga gtcggctttg gaagattttt atggagacca gcagtttgcc
     7561 tctagtttac gggagtctgt tctctattct attcatgctg gtggcaagcg tattcggcct
     7621 tttctcttgt tagaagttct ggaagccttg caggttgcca tcaaacctgc tcacgcgcag
     7681 gtagctactg ccttggagat gattcataca gggagcttga ttcacgatga ccttcctgct
     7741 atggatgatg acgattatcg aagagggcgg ttaaccaatc acaagaaatt cggtgaagct
     7801 atggccattt tggctggaga tgccttattc ttagacccat atgccttgat tgcgcaggca
     7861 gatttgccaa gtcagatcaa ggtggacttg attgccaact tatcccttgc ttcaggtagt
     7921 ctgggtatgg tggcagggca agttttggat atggagggcg aacaccagca cttgtctctg
     7981 gaagaacttc agactattca tgccaataag actgggaagt tactagccta tcccttccaa
     8041 gcggcagcta ttatagctga attgtcacct gaaatgcagg tgaagctgaa aactgtgggt
     8101 gaattgattg gacttgcttt tcaagtcaga gatgatgtac tggatgtgac agctagtttt
     8161 gaggaaatcg gtaagacacc tcaaaaggat ctgcaggcag aaaaatcaac ctatcctgcc
     8221 ttgttgggct tggaagagtc cattgccttt tgtaaccaaa ccctggatca agctaatgaa
     8281 aaattggaag aaattgccca gcaggttccc tttgaaacag aatcgattgt aagtgtagta
     8341 gaaagtttga gaatcaatgg ctaaggaaag agtggatgta ctagcttata aacaggggtt
     8401 gtttgaaacg agagagcagg ccaagcgagg tgtgatggct ggcctagtcg tagcagtcct
     8461 taatggagaa cggtttgaca agccaggaga gaaaattcca gatgataccg aattaaaact
     8521 caagggggag aaactcaagt atgtcagccg tggtggtttg aaactggaaa aggccttgca
     8581 ggtctttgat ttgtcggtgg atggcgcgac tacgattgat atcggggcct ctactggagg
     8641 ttttaccgat gtcatgctac agaatagtgc caagttggtc tttgcagtcg atgttggtac
     8701 caatcagttg gcttggaaat tacgccaaga cccacgagtt gtcagcatgg agcagttcaa
     8761 tttccgctat gctgaaaaga ctgatttcga gcaggagccg agctttgcca gtattgatgt
     8821 gagtttcatt tcccttagtc tgattttgcc agccttgcac cgtgtcttgg ctgatcaagg
     8881 tcaggtggta gcacttgtca aacctcagtt tgaggcagga cgtgagcaga ttgggaaaaa
     8941 tggaattatt cgagatgcta aggttcatca gaatgtcctt gaatctgtaa cagctatggc
     9001 agtagaggta ggtttttcag tccttggctt ggacttttct cccatccaag gtggacatgg
     9061 aaatattgaa tttttagcgt atttgaaaaa agaaaagtca gcaagcaatc agattcttgc
     9121 tgagattaaa gaagcagtag agagggcgca tagtcaattt aaaaatgaat aaaaaagaga
     9181 gacttgaaaa aattagaaga ttggtgacag attatcaaat cggcacgcaa gaagaaattg
     9241 tagaacattt gaaagaagca ggtatcactg ccactcaggc gacggtatcc cgagatatca
     9301 aagagttagg tattgtcaaa attcctttga gagacaacac ctatgtctac gaattgccaa
     9361 aatcaatcgt aaaaagtctg caactggctg aagacaatat cgaatcggct gaattgatgg
     9421 ataagatgat caatctccaa gttattccag gaaatacggc ttttgtaaaa gctcagttaa
     9481 tcgagacttt tgcagacaag atttttagct gtttgactga tgatagctcg attttagtca
     9541 ttgccagaag tggaagtcta gcagaggaaa tctttgaaca agtaaaaaat tggtaggtct
     9601 atatgttact tgaaatttcg ataaaaaact ttgccattat tgaggctatt tccctcaatt
     9661 ttgaaaaggg gatgactgtc ctgactggtg aaacgggtgc agggaagtcg attatcattg
     9721 atgccatgaa tatgatgttg ggagctcgtg cgacgacaga tgttattcgt catggtgcac
     9781 caaaggcaga gattgagggg cttttctcag ttgagaatag tcgtctttta caggaaattt
     9841 ttgatgagca aggtttagaa ttaggtgatg aaattatcat ccgtcgggaa atcttgcaaa
     9901 atggtcgtag tatcagccgt gtaaatggtc agatggttaa tctgtctgtt ttgcgagcta
     9961 ttgggcaaca tcttgtagat attcatggtc agcatgacca tgaggagtta atgcgtcccc
    10021 aactgcatat ccagatgttg gatgaatttg gtgatgccgc tttttgggac ttgaaagaaa
    10081 cctatcaaac gagttttgat gcctatcgga aaatgcgcaa gcaggttctg gaagtcaaga
    10141 aaaaccaaca ggaacacaag gcacgtatcg aaatgttgga atttcaaatg gcagagattg
    10201 aggcagcaaa cttgcaggct ggagaagact tggctctcaa tcaagagcga gataaactcc
    10261 tcaaccacaa aaatattgcg gatacactga ccaatgccta cagtatgttg gacaatgaag
    10321 atttttcaag tctggccaat gttcgttcag ctatgaatga catggaaagt gtcgaagagt
    10381 atgatcctga ataccgtgaa atttcaagct ctctgtctga gacctactat gttttagaag
    10441 acattagcaa acgtttggaa gctatcattg aggaccttga ttttgatggc aatcgcctca
    10501 tgcaggttga gaatcgtttg gacctccttc atactattac tcgtaagtat ggtgggactg
    10561 ttgatgatgt tttgctttat tttgccaaga ttacggaaga atacaatctc ttgacaggca
    10621 ataatctttc gtctgaggac atggaagcag agcttaagaa gttggaagtc aatcttgtca
    10681 atttggcagg tcaacttgct tctgctcgtc ataatttggc tcagcaactc gaagctgaga
    10741 ttaaacaaga actgcaagat ctttatatgg aaaaagccca gtttcaggtt cgttttagta
    10801 agggaaaatt cagtcgtgag ggaaatgaaa tggttgagtt ttatatttca accaaccctg
    10861 gagaagactt taaacccttg gttaaggttg cttctggagg ggaattatct cgtctcatgt
    10921 tagccattaa gtctgccttt tcacgtaaag aaggcaagac tagcattgtc tttgatgagg
    10981 tggatacggg agtttcaggt cgtgttgctc aagctattgc tcagaaaatt cataaaattg
    11041 gtcagtatgg tcaggttttg gctatctccc atttgccaca agtaattgcg attgcagatt
    11101 atcaattctt tattgagaag attagtaatg accattcaac ggtttcgact gttcgtctct
    11161 tgacagtcga agagcgagtg gaggaagttg ccaagatgtt ggcaggtgat gatgtgacag
    11221 aagcagccct gacgcaagcc agagaattgt tgagaaacag ggagaaataa gatgacagat
    11281 tattatgtaa ttggagatgt tcacggaaaa gctgggatgc tggaagacct tcttaaaacc
    11341 tgggatggtc agacccagtt gctctttcta ggtgatttga ttgacagagg tgaggatagt
    11401 caccgtgttc ttgaaatggt caaggacttg gtggacaatc aaggggctat ctgtttgtct
    11461 ggaaaccacg agtatatgtt tttgacttgg ctagatgacc cagaagaaag ttatgaccat
    11521 tatcgtcgaa attgtggaga tacaaccatt aactctatcc taggtcgtcc cttggatgca
    11581 ccagttgatg gagtagaaga tgccaagcgg gttgccgctg aagcggcaga cttggtcgaa
    11641 ttcattcgtc aaatgccatt tgtagtagag acagacaagt atatctttgt tcacgcaggt
    11701 attgatttga ccttggacga ctggcatgaa acaacagatt ataaaaaagt atggcttaga
    11761 aaaccattcc acggagctga aaatcatact ggaaaaacca ttgtcttcgg tcatacaccg
    11821 gtctatggtt tgttacagca agaacgcggt acatctgagc tttggactac agaagatggc
    11881 aagattggaa tggatggagg agctgtttat ggtggtgtcc ttcacgggat tgtctttaca
    11941 gaccaaggaa tgacagaaca ccactttatc gaaaatgacg gctttgtcgc tgaagattag
    12001 tactcctagc agggtatggt cttgtcaaaa tatcaaaaac aatttataat aaatagatac
    12061 cctgaaagga agagaatcat gaacttagaa gaattgaaaa aacgacagga gaagatccgt
    12121 aacttctcta ttatcgccca tattgaccat ggaaaatcaa ctctagcaga ccgcattttg
    12181 gaaaaaacag agacggtttc aagtcgtgaa atgcaggccc agcttttgga tagcatggag
    12241 ctagagcggg aacgtggaat tactattaag ttgaatgcca tcgagttgaa ttacactgca
    12301 aaagatgggg aaacttatat tttccatttg attgacacac cagggcacgt tgactttacc
    12361 tatgaagttt cacgttcgct agctgcctgt gagggtgcta ttttggtggt cgatgcggct
    12421 caaggaattg aggctcaaac tcttgccaac gtttatctgg ctttggataa tgatttggaa
    12481 atcatgccta tcattaataa aattgacctg ccggctgcag atccggagcg cgtgcgtaca
    12541 gagattgaag atgtgattgg tttggatgcc agtgaagcag ttttggcttc tgccaaggct
    12601 ggtattggga ttgaagaaat cctcgagcaa attgtagaaa aagtaccagc accaacgggt
    12661 gatgtgacgg cgccacttaa ggccttgatt ttcgactctg tttacgatgc ttaccgtggg
    12721 gttatcctcc aagtgcgtgt catggacgga gtggtcaaac ctggtgataa gattcagctc
    12781 atgagcaata gtaagacctt tgatgtggcc gaagtcggta tttttacacc aaaagcggtt
    12841 ggtcgtgatt tccttgcgac tggtgatgtt ggttacattg cggcgtctat caagacggtt
    12901 caggatactc gtgtgggtga taccgttacc ttggcaacca atcctgcggc agaaccatta
    12961 catggttata agcagatgaa tcctatggtc tttgcgggtc tctacccaat cgaatcaaac
    13021 aaatacaatg acctgcgtga agcgcttgaa aaattgcaac tgaatgatgc tagtcttcag
    13081 tttgaaccag aaacatctca ggcacttgga tttggtttcc gttgtggatt tcttggactt
    13141 ctccatatgg atgttatcca ggaacgttta gagcgtgagt tcaatattga cctcatcatg
    13201 acagctccgt ctgttattta caaagttaat ttgaccgacg gtgagtctat ggatgtgtct
    13261 aacccatctg agtttccaga cccaactaag attgcgacca ttgaagagcc ttatgtcaag
    13321 gcgcaaatca tggtaccaca ggagttcgtc ggagcagtaa tggagctagc tcagcgtaag
    13381 cgtggggact ttgtgactat ggactatatt gatgataacc gtgtcaatgt tatctatcaa
    13441 attcctcttg ctgaaattgt ctttgacttc tttgataaac ttaagtcttc gacacgtggt
    13501 tatgcaagct ttgactacga attgtcagaa tatcgcccat ctaagctggt gaaaatggat
    13561 atccttctca atggagataa ggtggatgcc ctcagcttta tcgttcacaa ggactttgcc
    13621 tacgaacgtg ggaaactcat cgttgataaa ctcaagaaaa tcatccctcg ccaacaattt
    13681 gaagttccaa tccaagcggc tattggacac aagattgtcg ctcgtactga tatcaaggcc
    13741 cttcgtaaga acgtacttgc taaatgttat ggtggtgacg tttctcgtaa gcgtaaactc
    13801 cttgaaaaac aaaaagctgg taagaaacgc atgaaatcca tcggatcagt tgaagttccg
    13861 caagaagcct tcctcagcgt cttgagtatg gatgaagaat aagttatcag aaatgccttt
    13921 ccttgttcac aggaaattta tataagaatc aatagtaaag caggcttaga tggtctgctt
    13981 ttttagtttt tatactcttc gaaaatctct tcaaaccacg tcagcgtcgc cttaccgtat
    14041 gtatggttac tgacttcgtc agtttcatct acaacctcaa aatcatgttt tgagctgact
    14101 tcgtcagttt catctacaac ctcaaaactg tgttttgagt aacctgcggc tagcttccta
    14161 gtttgctctt tgattttcat tgagtattag aacagaaaaa tgcttggagt atttgtttgt
    14221 gtgtttattt ttatataaca aactataaac aaaacaaaaa tataaaaaaa gagacaaaaa
    14281 agaatagaaa gtaattaaca acgatttcat atagtgttat acttatagca taaagttaat
    14341 ggaaagaagg gaaaacctta tggtattaga ttatttcttt gacaaaaacc ttgtgttttg
    14401 cttagaagcg gataatcaag aacaactctt tgatcaggta gcaagcttgt tggaagaacg
    14461 agaaattgtc actccaactt atcgtgaagc cttgatcacg cgtgaaaagt catttccaac
    14521 tggtttagat atggaatttc taggaaagga cttgccaaat gtagcgattc ctcacacaga
    14581 tattgttcat aatctagctg aaaaagtggt ggttgttcga ttagaaaaac cagtaacttt
    14641 tcacaatatg attgcgccag gtaaggaagt agaagtatcc ctactcttct ttatcattaa
    14701 caattcaagt tcaagtcaaa caaatattct ggctcagttg atg
//
LOCUS       DAVBOG010000049        14344 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.049, whole genome shotgun sequence.
ACCESSION   DAVBOG010000049 DAVBOG010000000
VERSION     DAVBOG010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14344)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14344)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14344
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.049"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(83..646)
                     /locus_tag="VQ865_001723"
     CDS             complement(83..646)
                     /locus_tag="VQ865_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3136031.1"
                     /translation="MKKRSNIAPIAIFFATMLVIHFLSSLIFNLFPFPIKPTIVHIPV
                     IIASIIYGPRVGVTLGFLMGLLSLTVNTITILPTSYLFSPFVPNGNIYSAIIAIVPRI
                     LIGLTPYLVYKLMKNKTGLILAGALGSLTNTIFVLGGIFFLFGNVYNGNIQLLLATVI
                     STNSIAELVISAILTLAIVPRLQTLKK"
     gene            complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ865_001724"
     CDS             complement(630..1181)
                     /gene="coaC"
                     /locus_tag="VQ865_001724"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HET3136032.1"
                     /translation="MANILLAVTGSIASYKSADLVSSLKKQGHQVTVLMTQAATEFIQ
                     PLTLQVLSQNPVHLDVMKEPYPDQVNHIELGKKADLFIVVPATANTIAKLAHGFADNM
                     VTSTALALPSHIPKLIAPAMNTKMYDHPVTQNNLKTLETYGYQLIAPKESLLACGDHG
                     RGALADLTIILERIKETLDEKTL"
     gene            complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ865_001725"
     CDS             complement(1193..1882)
                     /gene="coaB"
                     /locus_tag="VQ865_001725"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000699493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HET3136033.1"
                     /translation="MKILVTSGGTSEAIDSVRSITNHSTGHLGKIITETLLSAGHEVC
                     LITTKRALKPEPHPNLSIREITNTKDLLIEMQERVQDYQVLIHSMAVSDYTPVYMTGL
                     EEVQASSNLKEFLSKQNHQAKISSTDEVQVLFLKKTPKIISLVKEWNPTIHLIGFKLL
                     VDVTEDHLVDIARKSLIKNQADLIIANDLTQISADQHRAIFVEKNQLQTVQTKEEIAE
                     LLLEKIQAYHS"
     gene            2112..3782
                     /locus_tag="VQ865_001726"
     CDS             2112..3782
                     /locus_tag="VQ865_001726"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019803354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HET3136034.1"
                     /translation="MKTDIEIAQSIELKPIVDVVEKLGISYDDLELYGKYKAKLSFDK
                     IRAVESNPVGKLILVTAINPTPAGEGKSTLTIGLADALNKIGKKTMIAIREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALIDNHLHQGNELGIDQRR
                     ILWKRVVDLNDRALRHVTVGLGGPLNGIPREDGFDITVASEIMAILCLATDIEDLKRR
                     LANIVIGYRYDRTPVSVGDLQVEGALALILKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSVLATTTALHLADYTVTEAGFGADLGAEKFLDIKTPNLPTSPDAVVIVATLRAL
                     KMNGGVAKDALTEENVEAVRAGFANLKRHVENIRKFGIPAVVAINEFVSDTEAEIAVL
                     KELCASIDVPVELASVWADGAEGGVALAETVVKTIAENPANYKRLYDNDLSVQEKIEK
                     IVTEIYRGSKVNFEKKAQTQIAQIVQNGWDKLPICMAKTQYSFSDNPNALGAPENFEI
                     TIRELVPKLGAGFIVALTGDVMTMPGLPKRPAALNMDVESDGTVLGLF"
     gene            4110..5285
                     /gene="mutY"
                     /locus_tag="VQ865_001727"
     CDS             4110..5285
                     /gene="mutY"
                     /locus_tag="VQ865_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HET3136035.1"
                     /translation="MLDLKEYGIVMWPEEKVISFREKLLAWYDENKRDLPWRRSKNPY
                     HIWVSEIMLQQTRVDTVIPYYERFLDWFPTVESLATAPEESLLKAWEGLGYYSRVRNM
                     QAAAQQIMTDFGGQFPNTYEGISSLKGIGPYTAGAISSIAFNLPEPAVDGNVMRVLAR
                     LFEVNHDIGIPSNRKIFQAMMEILINPDRPGDFNQALMDLGSDIESPVNPRPEESPVK
                     DFSAAYQNGTMDRYPIKSPKKKPVPIYLKALVVKNSQGQFLLEKNESEKLLAGFWHFP
                     FIEVDNFSQEEQFDLFHQVAEESVNSGPSPEESFQQDYDLDVDWLDVCFDTVQHVFSH
                     RKWHVQIVAGQVSDFHDFSDREVRWLSPEEFKNYPLAKPQQKIWQAYAQANLDSSQD"
     gene            5341..6045
                     /locus_tag="VQ865_001728"
     CDS             5341..6045
                     /locus_tag="VQ865_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000722069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3136036.1"
                     /translation="MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAE
                     QPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSAKDSEFDKVIGLELGADDYVTKP
                     FSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT
                     HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPE
                     YILTRRGVGYYMRNNA"
     gene            6038..7387
                     /gene="vicK"
                     /locus_tag="VQ865_001729"
     CDS             6038..7387
                     /gene="vicK"
                     /locus_tag="VQ865_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000886221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     VicK"
                     /protein_id="HET3136037.1"
                     /translation="MLDLLKQTIFTRDFIFILILLGFILVVTLLLLENRRDNIQLKQI
                     NQKVKDLIAGDYSKVLDMQGGSEITNITNNLNDLSEVIRLTQENLEQESKRLNSILFY
                     MTDGVLATNRRGQIIMINDTAKKQLGLVKEDVLNRSILELLKIEENYELRDLITQSPE
                     LLLDSQDINGEYLNLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSH
                     ELRTPLTSVKSYLEALDEGALCETVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATS
                     HLDVELINFTAFITFILNRFDKMKGQEKEKKYELVRDYPINSIWMEIDTDKMTQVVDN
                     ILNNAIKYSPDGGKITVRMKTTEDQMILSISDHGLGIPKQDLPRIFDRFYRVDRARSR
                     AQGGTGLGLSIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEVED"
     gene            7389..8198
                     /locus_tag="VQ865_001730"
     CDS             7389..8198
                     /locus_tag="VQ865_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001861619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HET3136038.1"
                     /translation="MSEIGFKYSILASGSSGNSFYLETSKNKLLVDAGLSGKKITSLL
                     AEINRKPEDLDAILITHEHSDHIHGVGVLARKYGMDLYANEKTWQAMENSKYLGKVDS
                     SQKHIFEMGKTKTFGDIDIESFGVSHDAVAPQFYRFMKDDKSFVLLTDTGYVSDRMAG
                     IVENADGYLIEANHDVEILRSGSYAWRLKQRILSDLGHLSNEDGAEAMIRTLGNRTKK
                     IYLGHLSKENNIKELAHMTMVNQLAQADLGVGVDFKVYDTSPDTATPLTEI"
     gene            8289..8531
                     /locus_tag="VQ865_001731"
     CDS             8289..8531
                     /locus_tag="VQ865_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HET3136039.1"
                     /translation="MTTITLKVSEADKTFMKAMAKFEGVSLSELIRTKTLEALEDEYD
                     ARVANLAYQEYLEDLEKGVEPITWEEMMHDLGLKDE"
     gene            8533..8787
                     /locus_tag="VQ865_001732"
     CDS             8533..8787
                     /locus_tag="VQ865_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HET3136040.1"
                     /translation="MYKLVPTRRFIKQLKKLDRYTQKLITNYLQTNVLEGPRRHGKAL
                     VGNRVGQWRYRIGNYRVIVQIVDDELVVATLEVGHRRDIY"
     gene            8834..9577
                     /locus_tag="VQ865_001733"
     CDS             8834..9577
                     /locus_tag="VQ865_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000731134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion transporter"
                     /protein_id="HET3136041.1"
                     /translation="MKKKCFFADYYDTTIILLALISVILVLLGFAEMIDLDNPPYSII
                     DLVIWGVFVIDYSWRFFITKRKWRFILENIFDLLAILPLNAIFTVFRLGRIFRLVKLT
                     KLLKLTRLLRIIGLIGKLERKISRFLRTNGLIYILYVNIFIVLVGSSILSVVEEKSFS
                     DSLWWALVTVTTVGYGDVVPTSIFGKWLAVLLMLVGIGTIGMLTSTLTNFFVKDNPDE
                     QIKLDKLKDELSSQRILIEKQSEKIEELH"
     gene            complement(9867..10853)
                     /locus_tag="VQ865_001734"
     CDS             complement(9867..10853)
                     /locus_tag="VQ865_001734"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019768616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HET3136042.1"
                     /translation="MTSTKQHKKVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLH
                     EKAVGDALDLSHALAFTSPKKIYAAQYSDCADADLVVITAGAPQKPGETRLDLVGKNL
                     AINKSIVTQVVESGFKGIFLVAANPVDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQ
                     ALAEKLDVDARSVHAYIMGEHGDSEFAVWSHANIAGVNLEEFLKDTQNVQEAELIELF
                     EGVRDAAYTIINKKGATYYGIAVALARITKAILDDENAVLPLSVFQEGQYGVENVFIG
                     QPAVVGAHGIVRPVNIPLNDAETQKMQASAKELQAIIDEAWKNPEFQEASKN"
     gene            11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ865_001735"
     CDS             11047..13515
                     /gene="gyrA"
                     /locus_tag="VQ865_001735"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003244540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HET3136043.1"
                     /translation="MQDKNLVNVNLTKEMKASFIDYAMSVIVARALPDVRDGLKPVHR
                     RILYGMNELGVTPDKPHKKSARITGDVMGKYHPHGDSSIYEAMVRMAQWWSYRYMLVD
                     GHGNFGSMDGDSAAAQRYTEARMSKIALEMLRDINKNTVDFVDNYDANEREPLVLPAR
                     FPNLLVNGATGIAVGMATNIPPHNLGETIDAVKLVMDNPEVTTKDLMEVLPGPDFPTG
                     ALVMGKSGIHKAYETGKGSIALRSRTEIETTKTGRERIVVTEFPYMVNKTKVHEHIVR
                     LVQEKRIEGITAVRDESNREGVRFVIEVKRDASANVILNNLFKMTQMQTNFGFNMLAI
                     QNGIPKILSLRQILDAYIEHQKEVVVRRTRFDKEKAEARAHILEGLLIALDHIDEVIR
                     IIRASETDAEAQAELMSKFKLSERQSQAILDMRLRRLTGLERDKIQSEYDDLLALIAD
                     LADILAKPERVSQIIKDELDEVKRKFSDKRRTELMIGQVLSLEDEDLIEESDVLITLS
                     NRGYIKRLDQDEFTAQKRGGRGVQGTGVKDDDFVRELVSTSTHDHLLFFTNKGRVYRL
                     KGYEIPEYGRTAKGLPVVNLLKLDEDESIQTVINVESDRSDDAYLFFTTRHGIVKRTS
                     VKEFANIRQNGLKALNLKDEDELINVLLAEGDMDIIIGTKFGYAVRFNQSAVRGMSRI
                     ATGVKGVNLREGDTVVGASLITDQDEVLIITEKGYGKRTVATEYPTKGRGGKGMQTAK
                     ITEKNGLLAGLMTVQGDEDLMIITDTGVMIRTNLANISQTGRATMGVKVMRLDQDAQI
                     VTFTTVAVAEKEEVGTENETEGEE"
     gene            13515..14258
                     /gene="srtA"
                     /locus_tag="VQ865_001736"
     CDS             13515..14258
                     /gene="srtA"
                     /locus_tag="VQ865_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000078846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase SrtA"
                     /protein_id="HET3136044.1"
                     /translation="MSQKNNKKKNKRKNLLTNILAGFLILLSLALIFNTQIRNIFIVW
                     NTNKYQVSQVSKEKLEENQDTEGNFDFDSVKAISSEAVLTSQWDAQKLPVIGGIAIPE
                     LEMNLPIFKGLDNVNLFYGAGTMKREQVMGEGNYSLASHHIFGVDNANKMLFSPLDNA
                     KNGMKIYLTDKNKVYTYEIREVKRVTPDRVDEVDDRDGVNEITLVTCEDLAATERIIV
                     KGDLKETKDYSQTSDEILTAFNQPYKQFY"
BASE COUNT         4393 a         2476 c         3188 g         4287 t
ORIGIN      
        1 ttttactata gtaaagattt cattaaaaag aaactgtata gagcaaaatc tccaccttca
       61 ggtttgaaag cggagattgt ttttattttt tcaaggtttg tagtcgtgga acaatggcta
      121 gggttagaat tgcagaaatg accaattcag caattgaatt tgttgagata acggttgcca
      181 gaagaagttg gatatttcca ttataaacat ttccaaatag gaagaagatt cctccaagga
      241 caaagatagt atttgtcaag gaaccaagag ccccagctaa aatcagacca gtcttgtttt
      301 tcatcagttt atagactaag taaggagtta aaccaatcaa aatacgtggg acaatggcaa
      361 tgatagctga gtagatgttt ccgtttggta cgaagggaga gaagaggtag cttgtcggta
      421 gaatcgtaat cgtgttaacc gtcaagctaa gtaatcccat caaaaatcca agtgtaaccc
      481 caactcgtgg accataaata atgctggcaa taatgacagg aatatgaaca atggtcggtt
      541 tgattggaaa tggaaaaagg ttaaagataa gtgagctcag aaagtgtatc acgagcatgg
      601 tagcaaaaaa gatagcaatg ggtgcaatat tagagcgttt tttcatcgag agtttccttt
      661 attctttcta aaataattgt gaggtcagct aaagctcctc gtccgtggtc tccacaagct
      721 agtagggatt ccttaggagc aatcagctga tagccgtagg tttctaatgt tttcagatta
      781 ttctgagtta ctggatggtc atacattttt gtattcatag caggagctat tagtttggga
      841 atatgacttg gtagggctag agctgtactg gttaccatgt tgtccgcaaa tccgtgagct
      901 agttttgcaa tagtgttagc agttgcaggt accacgataa ataaatctgc tttttttcca
      961 agttcgatat gattgacctg atcaggatag ggttccttca tgacatccaa gtggacagga
     1021 ttctgtgaga gtacctgtag tgtcaaaggt tggataaact ctgtagcagc ctgagtcatt
     1081 aagacagtga cttgatggcc ttgttttttt agagaactga ctaaatctgc cgacttataa
     1141 gaggcgattg aacccgttac agccaagaga atgtttgcca tagttttcct ttctaagaat
     1201 gataggcttg aattttttca aggaggagtt ctgcaatttc ttctttagtc tggactgttt
     1261 gaagctgatt tttctcaaca aatatagctc ggtgctgatc tgctgaaatt tgagtcaggt
     1321 cattcgcgat gattaaatct gcttgattct tgataagact ttttcgtgca atgtcaacca
     1381 gatgatcttc ggtaacatca accagcagtt tgaaaccaat cagatgaata gtaggattcc
     1441 attccttgac tagggatatg attttgggtg tctttttaag gaacaaaacc tgaacctcat
     1501 cagttgaaga aatcttggcc tgatgattct gcttgcttaa aaattctttt agattggagc
     1561 tagcctgaac ttcctcaagc cctgtcatat aaacaggagt gtagtcagaa acagccattg
     1621 agtggatcaa gacctgataa tcctgaacac gttcttgcat ttctattaga aggtccttgg
     1681 tattggtaat ttctcgaata cttaggttag gatgaggctc tggcttcaga gctcgttttg
     1741 tcgtaattaa acaaacttca tgccctgcag aaagcaaagt ctctgtgata attttcccca
     1801 agtgacctgt agaatggtta gtgatagagc ggacgctatc gatagcttca ctggtaccgc
     1861 ccgatgtaac taaaattttc atagcactat tgtacacaaa aataagcggt aagtaaaatg
     1921 aaagtgataa atttttggta aaaacgaaga tttattatag tttcaaacta taaagccata
     1981 taaaatttaa gaaaggactc taaaagtctt aaaaacagag atatttacga acgtttagag
     2041 agttttagga tgttaaaaat cttgttttgt gatataatga attatcatat aagaggttag
     2101 aggaattttg aatgaaaaca gatattgaaa tcgcacagag tattgagttg aagccaattg
     2161 ttgatgttgt agagaaactt ggtatttctt atgacgattt ggagttgtac ggaaagtaca
     2221 aggctaaact cagctttgat aaaattcgtg cagttgagag caatccagtc ggtaaattga
     2281 tcttggttac tgccatcaac ccaacacctg caggtgaagg aaagtcgacg cttaccattg
     2341 gtcttgcgga tgccttgaac aagattggca agaaaaccat gattgctatc cgcgaaccgt
     2401 ctcttggtcc agtcatgggg atcaagggtg gtgctgctgg tggtgggtat gcacaagttc
     2461 tgccaatgga agacatcaac ctccacttta ctggagatat gcatgctatt acaactgcca
     2521 acaatgccct ttctgccttg attgacaacc acttgcacca agggaatgag ctgggaattg
     2581 atcaacgtcg tatcctctgg aaacgcgttg tggacttgaa cgaccgtgcg ctccgccatg
     2641 tgactgttgg tcttggtggt cctctaaacg gtattccacg tgaggacggt tttgatatta
     2701 cagttgcttc agaaatcatg gcaattcttt gcttggcaac ggacatcgag gacttgaaac
     2761 gtcgtttggc gaatatcgtt attggttatc gctatgaccg tacgcctgtt tctgtaggtg
     2821 atttgcaggt tgagggtgcc ttggctttga ttttgaagga tgctattaag ccaaacttgg
     2881 ttcagacaat ttacggtaca cctgcctttg tacacggtgg tccatttgcc aatatcgctc
     2941 atggctgtaa ctctgttttg gcgacgacaa cagcccttca cttggctgat tacactgtta
     3001 ctgaagctgg ttttggtgcg gatcttggtg ctgagaaatt ccttgatatc aagacaccaa
     3061 acttgccaac atctccagat gcagttgtta ttgtcgcaac ccttcgtgcc cttaagatga
     3121 atggtggtgt ggctaaagac gctctgactg aagaaaatgt agaggcagtt cgtgcaggtt
     3181 ttgctaactt gaaacgccac gttgaaaata tccgtaagtt cggtattcca gcagttgtag
     3241 ctattaacga atttgtatct gatacagaag ctgaaattgc agtcttaaaa gaactctgtg
     3301 cctcaatcga tgtaccagtt gaattggcta gtgtctgggc tgatggagca gaaggtggag
     3361 tagcacttgc cgaaacagtt gttaagacaa ttgctgaaaa tccagctaac tataaacgtt
     3421 tgtacgataa tgatctttct gtccaagaaa agattgaaaa aattgtcact gaaatctatc
     3481 gtggtagcaa agtgaacttt gagaagaaag ctcaaacaca aattgctcaa atcgttcaaa
     3541 acggttggga caaattgcca atttgtatgg ctaaaactca atacagtttc tcagacaatc
     3601 caaatgcgct tggagcacca gaaaactttg aaattaccat tcgtgaattg gtaccaaaat
     3661 taggtgcagg cttcatcgtt gccttaactg gtgatgttat gaccatgcca ggtcttccaa
     3721 aacgtccagc agctctcaac atggatgttg aaagcgatgg aactgtgcta ggcttgttct
     3781 agtggattga aattgacttt aagtgagttt ggaaataata tccaagctca ttttttctca
     3841 gactgcaagc agttcatcaa taagatttat actcttcgaa aatcttttca aactacgtca
     3901 gcttcacctt gccgtaggta tatgatactg actctgtcag ttctatccac aacctcaaaa
     3961 cagtgttttg agcaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
     4021 aagtagatag aaaagttata tactatctat tgaaaatatt ataaatcaga tacaaagaca
     4081 ggtgaaacct tctgtgttat actagagata tgttagattt gaaagaatac ggtatcgtca
     4141 tgtggccgga ggagaaagtc atttctttcc gtgagaaact tctcgcttgg tatgatgaaa
     4201 acaaaagaga tttgccttgg aggagaagta aaaatcctta tcacatctgg gtatctgaaa
     4261 tcatgcttca gcagaccagg gtggatacag ttatccctta ctacgaaaga tttttggact
     4321 ggtttccaac tgtcgaaagt ctggcaactg cgcctgagga gagtttactg aaagcttggg
     4381 agggcttggg ctattattct cgagttcgca atatgcaggc tgcagcccag cagattatga
     4441 ctgactttgg tggccaattt ccaaatacct atgaaggaat ttccagcttg aaagggattg
     4501 gaccttacac agcaggagcc atttccagta ttgcttttaa cttgcctgag ccagctgtag
     4561 atggtaatgt catgcgggtc ttggcgcgtc tgtttgaagt caaccacgat attgggattc
     4621 caagtaatcg aaaaattttt caggcaatga tggagatctt gattaatcca gatcgtccgg
     4681 gtgattttaa tcaagccttg atggacttag ggtctgatat tgagtctcct gtaaatccca
     4741 gacctgaaga aagcccagtc aaggacttta gtgcggcata tcagaatgga accatggacc
     4801 gttatccaat taaatctcct aagaaaaagc cggttcctat ttatcttaaa gccttagttg
     4861 tgaaaaattc tcaaggacaa tttttacttg aaaaaaatga aagcgaaaag ctcttggcag
     4921 gtttttggca tttccccttt atagaagttg ataacttttc gcaagaagag cagtttgacc
     4981 tctttcatca ggttgcggaa gaaagtgtga actctggccc cagtccagaa gagagtttcc
     5041 agcaggacta tgacctagat gttgattggc ttgatgtttg ttttgataca gtccagcatg
     5101 tttttagtca tcgaaaatgg catgtacaga ttgtagcagg tcaggtgagt gacttccatg
     5161 atttttcaga tagggaagtt cgttggcttt caccagaaga attcaagaat tacccacttg
     5221 ccaaacccca acaaaaaatc tggcaggctt atgcacaagc caacttagac agtagccaag
     5281 actagctatt gtgtcttctg actatttttt tggtataata gtagagaaaa aggtgaacat
     5341 atgaaaaaaa tactaattgt agatgatgag aaaccaatct cggatattat caagtttaat
     5401 atgaccaagg aaggttacga agttgtaact gcttttaatg gtcgtgaagc gctagagcaa
     5461 tttgaagcag agcaaccaga tattattatt ctggatttga tgcttccaga aattgatggt
     5521 ttagaagttg ctaagaccat tcgtaagaca agcagtgtgc ccattcttat gctttcagcc
     5581 aaagatagtg aatttgataa ggttatcggt ttggaacttg gggcagatga ctatgtaacg
     5641 aaacccttct ccaatcgtga gttgcaggcg cgtgttaaag ctcttctgcg tcgttctcaa
     5701 cctatgccag tagatggtca ggaagcagat agtaaacctc aacctatcca aattggggat
     5761 ttagaaattg ttccagacgc ctacgtggct aaaaaatatg gcgaagaact agacttaacc
     5821 catcgtgaat ttgagctttt gtatcattta gcatcgcata caggtcaagt catcacgcgc
     5881 gaacacttgc ttgagactgt ctggggttat gactattttg gtgatgtccg tacagttgat
     5941 gtgactgtac gacgtctgcg tgagaagatt gaagatacgc ccagccgacc agagtatatc
     6001 ttgacacgcc gtggtgtagg gtattacatg agaaataatg cttgatttac tgaaacaaac
     6061 catttttacc agagatttta tctttatcct gattttgtta ggtttcatcc ttgttgtgac
     6121 cctcttatta ctggaaaata gacgtgataa tattcagttg aagcaaatca atcaaaaggt
     6181 taaagatttg attgcaggag attattccaa ggttcttgat atgcaaggtg ggtctgaaat
     6241 caccaatatt accaataatt tgaatgactt gtcggaggtt attcgtctca ctcaggaaaa
     6301 tctagaacaa gagagtaaga ggctaaatag tattctgttt tatatgacag atggggttct
     6361 tgcgaccaac cgtcggggtc agattatcat gattaacgat acagccaaga agcaactggg
     6421 gttggttaag gaagatgttc tgaatagaag cattttggaa ttgctcaaga tagaagaaaa
     6481 ctatgaattg cgtgatttga ttacccaaag tccagaattg ttgctagatt cccaagatat
     6541 caatggtgaa tatttgaacc ttcgagttcg ctttgccttg atacgtcgag agtctggctt
     6601 tatttcaggt ttggtggctg ttttgcatga tacgacggag caggagaagg aagaacgcga
     6661 acgaagactc tttgtttcca atgttagcca tgagttacgg actcctctga ctagcgtaaa
     6721 atcctatctt gaagccttgg atgagggggc tttgtgtgaa actgtagcac cagactttat
     6781 caaggtttct cttgatgaga ccaaccgtat gatgcgcatg gtgacggatc tcctccatct
     6841 ttcacgtatt gataatgcta ccagtcacct agatgtggaa ctgattaact tcactgcttt
     6901 tattaccttt atcctcaatc gttttgacaa gatgaaagga caggaaaagg agaaaaaata
     6961 tgagttggtg agagattatc ccatcaattc tatctggatg gaaattgata cagataagat
     7021 gacgcaggtt gtcgacaata ttttaaataa tgctattaaa tattcgccag atgggggtaa
     7081 aatcactgtc agaatgaaga caactgaaga ccagatgatt ttatccattt ctgaccacgg
     7141 tttggggatt cctaagcagg atttaccacg tatctttgac cgtttctatc gtgtggatcg
     7201 tgctagaagt cgtgcacaag gtggtacagg tctaggactg tctatcgcta aagaaattat
     7261 caaacaacat aagggcttta tttgggccaa gagtgaatac ggcaagggtt caacctttac
     7321 cattgtgctc ccttatgata aggatgcagt gaaagaagaa gtatgggagg atgaagtaga
     7381 agactagaat gagtgaaata ggctttaaat acagtatttt agcgtcgggt tccagtggaa
     7441 attcttttta tctggaaacc tcaaaaaata agcttttagt agatgcaggc ttgtctggca
     7501 agaaaattac cagtctgcta gctgaaatta accgtaagcc agaagacctg gatgccatct
     7561 tgattaccca tgagcattca gatcatatcc atggagtagg cgttttggct cgcaagtatg
     7621 gtatggatct ttatgccaat gaaaagacct ggcaagctat ggaaaatagt aaatatcttg
     7681 gcaaggtgga ttcttcgcaa aagcatattt ttgaaatggg taaaaccaaa acctttggag
     7741 atatcgacat cgagagtttt ggtgtaagcc atgatgcagt cgcaccgcag ttctatcgct
     7801 ttatgaagga tgataagagt tttgtccttt tgacagatac aggttatgtc agtgaccgta
     7861 tggcgggcat tgtcgaaaat gcggatggct atcttatcga ggccaaccat gatgtagaga
     7921 ttttgcgatc aggttcttac gcttggcgac tcaaacaacg aatcctatct gaccttggtc
     7981 acctttctaa cgaggacggt gctgaagcta tgattcggac gctaggaaat cgtactaaga
     8041 agatttacct tgggcattta tctaaggaaa ataatatcaa ggaactggct catatgacca
     8101 tggtcaatca gctggctcaa gctgatctgg gagtcggagt agactttaag gtttatgata
     8161 cctcaccaga taccgcaaca ccattgacag agatataaaa agaacgctga gaaggtgttc
     8221 tttttatatt gactgaacac ctaaaaagta atacaatggt gttaccatta aaaaagggag
     8281 cacaaaagat gactactatt acattaaaag tttctgaagc tgataaaaca tttatgaaag
     8341 caatggctaa gtttgaagga gtttcccttt cggaacttat tcgcaccaaa actcttgaag
     8401 ccctagaaga tgaatacgat gctcgtgtgg caaatttagc ctatcaagag tatttagaag
     8461 acttggaaaa aggagttgaa cccattactt gggaagaaat gatgcatgat ttaggcttga
     8521 aggatgaata atttgtataa attagttcca acaagacgtt ttatcaagca attgaaaaaa
     8581 ttggaccgtt atacgcagaa gctaattaca aactatttac aaaccaatgt tttggaaggc
     8641 ccaagacgac acggaaaggc tttggttggt aatcgcgttg gtcaatggcg ctatagaatt
     8701 ggtaattatc gagttatcgt acaaattgta gatgatgaat tagtcgttgc tactctagaa
     8761 gttggtcatc ggagagatat ttattgaatt aaagctgagt aataacaata tagaaagtaa
     8821 ggagagtaaa aatttgaaga aaaaatgctt ttttgcagat tattatgata caacaattat
     8881 tttacttgct ttaatctctg ttattctggt attacttgga tttgctgaga tgattgattt
     8941 ggacaatccg ccttatagta ttattgattt agtaatctgg ggtgtttttg taattgatta
     9001 tagttggcgc ttttttatta ctaaaagaaa atggcgcttt attcttgaaa atatttttga
     9061 tttattggct attctccctt taaatgctat tttcacagtt tttcgattag ggcgtatctt
     9121 tcgtttagtt aaactaacaa aattactgaa actgactcgt ttacttagaa taattggact
     9181 tataggtaaa ttagaaagaa aaattagtag attcttacgg acaaatggcc tgatttatat
     9241 cttatatgtt aatatcttta ttgttctagt agggagttcg attttatccg ttgttgaaga
     9301 aaaatccttc tcagatagtc tctggtgggc tcttgtgacg gtaactactg ttggttatgg
     9361 tgatgttgtt cctacttcaa tttttggtaa atggttagct gtcttattaa tgcttgtcgg
     9421 tattgggaca ataggaatgt taacgagtac cttgacgaac ttttttgtaa aggataatcc
     9481 agatgaacag ataaaacttg ataaactcaa agacgaatta tcgagccaaa gaatattaat
     9541 agagaaacaa tctgaaaaaa tcgaagaact acattgaatg ataaaagact tagttgaaaa
     9601 aatatcataa aggtgagaca aaacaaaact tgattcgagg agaaatcaag taagtcttga
     9661 cacaatagaa cgcatattat caggtataaa aacttgatac tatgcgtttt atagagaaat
     9721 aaaataaaat ctgaacaaat caattaggaa tttaaagcat tttataacaa cgttttagag
     9781 tgatagggtg ctatttcaac ttcaacctac tataatacag aaaaaaaaca actccctgat
     9841 gattcaagga gttgtctata gttaaattag tttttagaag cttcttggaa ttctggattt
     9901 ttccatgctt cgtcaataat agcttgcaat tctttagcag atgcttgcat tttttgagtt
     9961 tctgcatcgt tcaatggaat gtttactgga cgaacgatac catgtgcacc aacaacagct
    10021 ggttgaccga taaagacatt ctcaactccg tattgacctt cttggaatac tgaaagtgga
    10081 agtactgcgt tttcatcgtc aaggattgct ttagtgatac gagcaagggc tactgcgata
    10141 ccgtagtatg ttgcaccttt tttgttgatg attgtgtagg ctgcatcacg aacaccttcg
    10201 aacaattcaa tcaattcagc ttcttgaaca ttttgagtgt ctttaaggaa ttcttcaagg
    10261 tttacaccag cgatgttagc gtgtgaccaa acagcgaact cagagtcacc gtgttcaccc
    10321 atgatgtagg cgtgcactga acgagcatcc acatccaatt tttcagcaag tgcttgacgg
    10381 aaacgagctg agtcaagtga agtacctgaa ccgataacgc gttctttagg gaaaccagag
    10441 aatttccaag ttgagtaagt caaaacgtca actgggttag cagcaacaag gaagatacct
    10501 ttgaaaccag attcaacaac ttgagttacg attgatttgt tgatagcaag gtttttacct
    10561 acaaggtcaa gacgagtttc acctggtttt tgaggtgcac ctgcagtgat cacaacaagg
    10621 tcagcgtctg cacagtcaga gtattgagct gcatagattt ttttaggtga agtgaaggca
    10681 agggcgtgac taaggtcaag cgcatcacca acagcttttt catgcaattg tggaatttcg
    10741 ataattccaa gctcttgtgc aattccttgg ttaacaagtg caaaagcgta agatgaacct
    10801 acagcaccat caccgacaag gataactttt ttgtgttgtt tagttgaagt cattgtttta
    10861 aacatctcct taattttatt aggggatttt ccctagacaa cttcattcta tcacttttaa
    10921 aaaactttgt cacgaatatg ccttatagtt cttgatgtaa acgttttagt ggtttagagg
    10981 ctgaaataga tgggaattta tggtataatg ttgttactta ctaattgtga aatgaggcat
    11041 ttattaatgc aggataaaaa tttagtgaat gtcaatctga caaaggagat gaaggcaagt
    11101 tttatcgact acgccatgag tgttatcgta gcgcgagctc ttcctgatgt tcgagatggc
    11161 ttaaaacctg ttcaccgtcg cattctctac ggaatgaatg aattgggtgt gaccccagac
    11221 aaaccccata aaaaatctgc tcgtattaca ggggatgtca tgggtaaata tcacccacac
    11281 ggggattcct ctatttatga agccatggtc cgtatggctc aatggtggag ctaccgttac
    11341 atgcttgtag atggtcacgg gaattttggt tccatggatg gagatagtgc tgccgctcaa
    11401 cgttataccg aggcacgtat gagcaagatt gctctggaaa tgcttcgtga tatcaacaaa
    11461 aatacagttg atttcgttga taactatgat gccaatgaac gggaaccctt ggtcttgcca
    11521 gcgcgttttc caaacctttt ggttaatgga gcaactggta tcgcggttgg gatggcaacc
    11581 aatattccac ctcataatct gggtgaaacc attgatgcag tgaagttggt catggataat
    11641 cctgaagtga ctaccaagga cttgatggaa gtcttgcctg gaccagattt tccaactggt
    11701 gctcttgtca tggggaaatc aggtatccat aaggcttatg aaacaggtaa aggttcgatt
    11761 gccctacgtt ctcgtacaga gattgaaacg actaagactg gtcgtgagcg catcgttgta
    11821 acagaatttc cttacatggt caataaaacc aaggtgcatg agcatattgt tcgcttggtt
    11881 caggaaaaac gcattgaggg tatcacagca gtacgtgatg agtcaaaccg tgaaggtgtt
    11941 cgatttgtta ttgaagtcaa gcgcgacgcc tcagccaatg ttattctcaa taacctcttc
    12001 aaaatgaccc aaatgcaaac caattttggt ttcaatatgc tcgctatcca aaatggtata
    12061 ccgaaaattt tgtctcttcg tcagattttg gatgcttata tcgagcacca aaaagaagtg
    12121 gttgttcgtc gtacacgttt tgataaggaa aaagcggaag cgcgcgctca tatcttagaa
    12181 ggtctcttga ttgcgctaga ccatatcgac gaagtgattc gtatcatccg tgctagtgaa
    12241 acggatgcgg aagctcaagc tgagttgatg agcaagttta agctttctga acgtcaaagt
    12301 caagctatcc ttgatatgcg tcttcgtcgt ttgacaggtt tggaacgcga taagattcaa
    12361 tctgagtatg atgacctctt ggctctgatt gcggatttag cagatattct tgctaagcct
    12421 gaacgtgttt ctcaaattat caaagacgaa ttggatgaag ttaaacgtaa attttctgat
    12481 aagcgccgta cagagttgat gattggacag gtcttgagtc tcgaggatga ggacttgatt
    12541 gaagaatcgg atgtcttgat taccctttct aacagaggct acattaagcg tttggatcag
    12601 gacgagttca ctgctcaaaa acgtgggggt cgtggtgtcc aaggaacggg agtgaaagat
    12661 gatgactttg ttcgtgagtt agtgtcaact agcacccatg atcatctgct cttcttcaca
    12721 aacaagggac gtgtctatcg tcttaaaggt tatgaaattc ctgagtatgg tcggactgcc
    12781 aaagggctac cagtagtcaa tctcttgaaa ttggatgaag acgaaagtat tcagacggtt
    12841 atcaatgttg agtctgatcg cagtgatgat gcttatctct tctttacaac ccgtcacggt
    12901 attgtgaaga gaaccagtgt taaggagttt gccaatattc gtcaaaatgg tctcaaagcg
    12961 ctgaatttaa aggatgaaga tgagttaatc aatgtcttgt tggcagaagg agatatggat
    13021 attatcattg gtaccaagtt tggttatgca gttcgcttta atcaatcagc cgttcgtggt
    13081 atgagtcgta tcgccactgg tgtaaaaggt gttaaccttc gtgaaggaga cacagttgtt
    13141 ggtgccagct tgattactga tcaagatgag gttcttatta tcacagaaaa aggatatggt
    13201 aagcgtacag tcgctactga atacccaaca aaaggtcgtg gtggtaaggg aatgcagaca
    13261 gctaaaatta ccgaaaaaaa tggcttgctg gccggtctta tgactgttca aggggatgag
    13321 gatttgatga ttatcactga tacaggtgtc atgattcgaa ccaatcttgc caatatttca
    13381 caaacaggac gtgcaactat gggagttaaa gtaatgcgcc tggatcaaga tgctcagata
    13441 gtgactttca caacggttgc ggtggcagaa aaagaagaag ttgggacaga aaacgaaaca
    13501 gaaggtgaag aataatgtct caaaaaaata ataaaaagaa aaacaagcga aaaaatctgc
    13561 tgacaaatat cctagcagga tttctgatat tactgtcact ggctttgatt tttaatactc
    13621 aaattcgaaa tattttcata gtctggaata ccaataagta tcaagttagc caggtatcaa
    13681 aagaaaaatt agaagaaaat caggatacag aaggcaattt tgactttgat tctgtcaaag
    13741 ctatctcttc ggaagctgtt ctaacttctc aatgggatgc tcaaaaatta ccagttattg
    13801 ggggaattgc aattcctgaa ttggaaatga atttgccgat ttttaaagga cttgataatg
    13861 ttaatctctt ctacggagct ggtacaatga aacgcgagca agtaatggga gaaggaaatt
    13921 atagtctagc tagtcaccat atctttggtg ttgataatgc taataaaatg ttattttctc
    13981 ctttagataa tgctaaaaat ggcatgaaga tttatctaac cgataaaaat aaagtttata
    14041 cttatgaaat acgtgaagtc aaacgtgtga caccggatcg tgttgatgaa gttgatgata
    14101 gagatggggt caatgaaatc acattagtaa cctgtgaaga ccttgctgct acagaacgta
    14161 ttattgtcaa aggtgatttg aaagaaacaa aagattattc acaaacatct gatgaaattc
    14221 taacagcttt caatcaacca tataaacaat tttattaata caaatcagtg aaatcatgga
    14281 tttcactgat tttttaagat tttcataaaa atatagtaaa atgaaataag aataggacga
    14341 atcg
//
LOCUS       DAVBOG010000050        14209 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.050, whole genome shotgun sequence.
ACCESSION   DAVBOG010000050 DAVBOG010000000
VERSION     DAVBOG010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 14209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14209
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.050"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(48..482)
                     /locus_tag="VQ865_001737"
     CDS             complement(48..482)
                     /locus_tag="VQ865_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3136045.1"
                     /translation="MDIWEKMYEEAQKLYNPHEVSDFVYANHVVAAVEAEDGQIFTGF
                     CMEGTCGVFHLCAERAALFNMYQFSGQTKVKKVLAFRDKPPYGGSSAMPCGACREFLL
                     ELNAENKDAEFMMDYNIRKTVKVAELIPYWWGEERASKFNER"
     gene            complement(496..1956)
                     /locus_tag="VQ865_001738"
     CDS             complement(496..1956)
                     /locus_tag="VQ865_001738"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007519940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HET3136046.1"
                     /translation="MSKDIRVRYAPSPTGLLHIGNARTALFNYLYARHHGGTFLIRIE
                     DTDRKRHVEDGERSQLENLRWLGMDWDESPESHENYRQSERLDLYQKYIDQLLAEGKA
                     YKSYVTEEELAAERERQEVAGETPRYINEYLGMSEEEKAAYIAEREAAGIIPTVRLAV
                     NESGIYKWHDMVKGDIEFEGGNIGGDWVIQKKDGYPTYNFAVAIDDHDMQISHVIRGD
                     DHIANTPKQLMVYESLGWEAPEFGHMTLIINSETGKKLSKRDTNTLQFIEDYRKKGYL
                     PEAVFNFIALLGWNPGGEDEIFSREELIKLFDENRLSKSPAAFDQKKLDWMSNDYIKN
                     ADLETIFEMAKPFLEEAGRLTDKAEKLVELYKPQMKSVDEIIPLTDLFFSDFPELTEA
                     EREVMTGETVPTVLEAFKAKLEAMTDDKFVTENIFPQIKAVQKETGIKGKNLFMPIRI
                     AVSGEMHGPELPDTIFLLGREKSIQHIENMLKEISK"
     gene            complement(2080..3429)
                     /locus_tag="VQ865_001739"
     CDS             complement(2080..3429)
                     /locus_tag="VQ865_001739"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HET3136047.1"
                     /translation="MSHIKFDYSKVLDKFVAPHEVEYMQSQVTAADELIRKGTGAGSD
                     FLGWLDLPEKYDREEFDRILKAAEQIKSDSDVLVVIGIGGSYLGAKAAIDFLNHHFAN
                     LQTKEERKAPQILYAGNSISSTYLADLVEYVADKDFSVNVISKSGTTTEPAIAFRVFK
                     ELLVKKYGQEEANKRIYATTDRQKGAVKVEADANGWETFVVPDDIGGRFSVLTAVGLL
                     PIAASGADIKALMEGANAARKDYTSDKISENEAYQYAAVRNILYRKGYATEILVNYEP
                     SLQYFSEWWKQLAGESEGKDQKGIYPTSANFSTDLHSLGQFIQEGTRIMFETVVRVDK
                     PRKNVLIPTLEEDLDGLGYLQGKDVDFVNKKATDGVLLAHTDGDVPNMYVTLPEQDAF
                     TLGYTIYFFELAIALSGYLNAINPFDQPGVEAYKRNMFALLGKPGFEELSKELNARL"
     gene            complement(3416..3595)
                     /locus_tag="VQ865_001740"
     CDS             complement(3416..3595)
                     /locus_tag="VQ865_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136048.1"
                     /translation="MEHLVVLSFIFSKFLECGILRKRLNSDKNWRNSTKKLEKNEGKR
                     YDRKEEILEEEHVTY"
     gene            complement(3599..4288)
                     /locus_tag="VQ865_001741"
     CDS             complement(3599..4288)
                     /locus_tag="VQ865_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016466883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HET3136049.1"
                     /translation="MARTVVGVAANLCPVDAEGKIIHSSVSCRFAEIIRQVGGLPLVI
                     PVGDESVVRDYVEMIDKLILTGGQNVHPQFYGEKKTVESDDYNLVRDEFELALLKEAL
                     RQNKPIMAICRGVQLVNVAFGGTLNQEIEGHWQGLPFGTSHSIETVEGSVVAKLFGKE
                     SQVNSVHRQSIKDLAPNFRVTAIDSRDQTIEAIESIDEHRIIGLQWHPEFLVNEEDGN
                     LELFEYLLNEL"
     gene            complement(4427..6193)
                     /gene="patB"
                     /locus_tag="VQ865_001742"
     CDS             complement(4427..6193)
                     /gene="patB"
                     /locus_tag="VQ865_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000859866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatB"
                     /protein_id="HET3136050.1"
                     /translation="MKTVQFFWHYFKVYKFSFVVVILMIVLATFAQALFPVFSGQAVT
                     QLANLVQAYQNGNPELVWQSLSGIMVNLGLLVLVLFISSVIYMCLMTRVIAESTNEMR
                     KGLFGKLAQLTVSFFDRRQDGDILSHFTSDLDNILQAFNESLIQVMCNIVLYIGLILV
                     MFSRNVTLALITIASTPLAFLMLIFIVKMARKYTNLQQKEVGKLNAYMDESISGQKAV
                     IVQGIQEDMMAGFLEQNERVRKATFKGRMFSGILFPVMNGMSLINTAIVIFAGSAVLL
                     NDKSIETSTALGLIVMFAQFSQQYYQPIIQVAASWGSLQLAFTGAERIQEMFDAEEEI
                     RPEKAPTFTKLQESVEISHIDFSYLPDKPILKDVSISAPKGQMTAVVGPTGSGKTTIM
                     NLINRFYDVDAGGIYFDGKDIRGYDLDSLRSKVGIVLQDSVLFSGTIRDNIRFGVPDA
                     SQEMVEVAAKATHIHDYIESLPDKYDTLIDDDQSIFSTGQKQLISIARTLMTDPEVLI
                     LDEATSNVDTVTESKIQHAMEVVVAGRTSFVIAHRLKTILNADQIIVLKDGEVIERGN
                     HHELLKLGGFYSELYHNQFVFE"
     gene            6391..6654
                     /locus_tag="VQ865_001743"
                     /pseudo
     CDS             6391..6654
                     /locus_tag="VQ865_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199219.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
     gene            complement(6984..8678)
                     /gene="patA"
                     /locus_tag="VQ865_001744"
     CDS             complement(6984..8678)
                     /gene="patA"
                     /locus_tag="VQ865_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit PatA"
                     /protein_id="HET3136051.1"
                     /translation="MLIQKIKTYKWQALASLLMTGLMVASSLLQPRYLQEVLGALLTG
                     KYEAIYSIGAWLIGVAVVGLVAGGLNVVLAAYIAQGVSSDLREDAFRKIQTFSYADIE
                     QFNAGNLVVRMTNDINQIQNVVMMTFQILFRLPLLFIGSFILAVQTLPSLWWVIVLMV
                     VLIFGLTAVMMGMMGPRFAKFQTLLERINAIAKENLRGVRVVKSFVQEKEQFAKFTEV
                     SDELLGQNLYIGYAFSVVEPFMMLVGYGAVFLSIWLVAGMVQSDPSVVGSIASFVNYL
                     SQIIFTIVMVGFLGNSVSRAMISMRRIREILDAEPAMTFKDIPDEELVGSLSFENVTF
                     TYPMDNEPMLKDVSFTIEPGQMVGVVGATGAGKSTLAQLIPRLFDPQNGAIKIGGKDI
                     REVSEGTLRKTVSIVLQRAILFSGTIADNLRQGKGNATLFEMERAANIAQASEFIHRM
                     EKTFESPVEERGTNFSGGQKQRMSIARGIVSNPRILIFDDSTSALDAKSERLVQEALN
                     KDLKGTTTIIIAQKISSVVHADKILVLNQGRLIGQGTHADLVANNAVYREIYETQK"
     gene            complement(8825..11359)
                     /gene="mutS"
                     /locus_tag="VQ865_001745"
     CDS             complement(8825..11359)
                     /gene="mutS"
                     /locus_tag="VQ865_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HET3136052.1"
                     /translation="MAIEKLSPGMQQYVDIKKQYPDAFLLFRMGDFYELFYEDAVNAA
                     QILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLIEQGYKVAIAEQMEDPKQAVGVV
                     KREVVQVITPGTVVDSSKPDSQNNFLVSIDREGNQFGLAYMDLVTGDFYVTGLLDFTL
                     VCGEIRNLKAREVVLGYDLSEEEEQILSRQMNLVLSYEKESFEDLHLLDLRLATVEQT
                     ASSKLLQYVHRTQMRELNHLKPVIRYEIKDFLQMDYATKASLDLVENARSGKKQGSLF
                     WLLDETKTAMGMRLLRSWIHRPLIDKERIVQRQEVVQVFLDHFFERSDLTDSLKGVYD
                     IERLASRVSFGKTNPKDLLQLATTLSSVPRIRAILEGMEQPTLAYLIAQLDAIPELES
                     LISAAIAPEAPHVITDGGIIRTGFDETLDKYRCVLREGTSWIAEIEAKERENSGISTL
                     KIDYNKKDGYYFHVTNSQLGNVPAHFFRKATLKNSERFGTEELARIEGDMLEAREKSA
                     NLEYEIFMRIREEVGKYIQRLQALAQGIATVDVLQSLAVVAETQHLIRPEFGDDSQID
                     IRKGRHAVVEKVMGAQTYIPNTIQMAEDTSIQLVTGPNMSGKSTYMRQLAMTAVMAQL
                     GSYVPAESAHLPIFDAIFTRIGAADDLVSGQSTFMVEMMEANNAISHATKNSLILFDE
                     LGRGTATYDGMALAQSIIEYIHEHIGAKTLFATHYHELTSLESSLQHLVNVHVATLEQ
                     DGQVTFLHKIEPGPADKSYGIHVAKIAGLPADLLARADKILTQLENQGTESPPPMRQT
                     SAVTEQISLFDRAEEHPILAELAKLDVYNMTPMQVMNVLVELKQKL"
     gene            complement(11410..11856)
                     /gene="argR"
                     /locus_tag="VQ865_001746"
     CDS             complement(11410..11856)
                     /gene="argR"
                     /locus_tag="VQ865_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3136053.1"
                     /translation="MRKRDRHQLIKKMITEEKLSTQKEIQDRLEAHNVCVTQTTLSRD
                     LREIGLTKVKKNDMVYYVLVNETEKIDLVEFLSHHLEGVARAEFTLVLHTKLGEASVL
                     ANIVDVNKDKWILGTVAGANTLLVICRDQHVAKLMEDRLLDLMKDK"
     gene            11993..13684
                     /locus_tag="VQ865_001747"
     CDS             11993..13684
                     /locus_tag="VQ865_001747"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009729659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HET3136054.1"
                     /translation="MNTKELIASELASIIDSLDQEAILKLLETPKNSEMGDIAFPAFS
                     LAKVERKAPQMIAAELAEKMNSQAFEKVVATGPYVNFFLDKSAISAQVLQAVTTEKEH
                     YADQNIGKQENVVIDMSSPNIAKPFSIGHLRSTVIGDSLSHIFQKIGYQTVKVNHLGD
                     WGKQFGMLIVAYKKWGDEEAVKAHPIDELLKLYVRINAEAENDPSLDEEAREWFRKLE
                     NGDEEALALWQWFRDESLVEFNRLYNELKVEFDSYNGEAFYNDKMDAVVDILSEKGLL
                     LESEGAQVVNLEKYGIEHPALIKKSDGATLYITRDLAAALYRKNEYQFAKSIYVVGQE
                     QSAHFKQLKAVLQEMGYDWSDDITHVPFGLVTKEGKKLSTRKGNVILLEPTVAEAVSR
                     AKVQIEAKNPELENKDQVAHAVGVGAIKFYDLKTDRTNGYDFDLEAMVSFEGETGPYV
                     QYAYARIQSILRKADFKPETAGNYSLNDTESWEIIKLIQDFPRIINRAADNFEPSIIA
                     KFAISLAQSFNKYYAHTRILDESPERDSRLALSYATAVVLKEALRLLGVEAPEKM"
     gene            complement(13999..>14209)
                     /locus_tag="VQ865_001748"
     CDS             complement(13999..>14209)
                     /locus_tag="VQ865_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3136055.1"
                     /translation="PRKSSKLKPLTVEDQAYNHALSKERSKVENIFAKVKTFKMFSTT
                     YRNHRKRFGLRMNLIAGIINHELGF"
BASE COUNT         4106 a         3195 c         2749 g         4159 t
ORIGIN      
        1 tattttttca acttatagta aaaagagcca aaattatact gactcttcta tcgctcatta
       61 aacttagaag cacgttcttc tccccaccaa taagggatta gttctgcgac tttaactgtt
      121 tttcttatat tatagtccat catgaattct gcatctttat tttcagcatt aagctctaaa
      181 aggaattctc tacaagcacc gcaaggcatg gctgaacttc caccataagg tggtttgtct
      241 cgaaaggcta atactttctt aaccttagtt tgtcctgaaa attggtacat attgaagagg
      301 gccgcccgtt ctgcgcagag atggaaaaca ccacaggttc cctccataca gaatcctgta
      361 aatatttgtc catcttctgc ttctactgca gctacaacat gattggcata aacaaagtct
      421 gatacttcat gtggattgta tagtttctgt gcttcttcgt acatcttttc ccagatgtcc
      481 attattgtat cctctttatt tagagatttc ttttagcatg ttttcgatat gctgaattga
      541 tttttcacgt ccaagcaaga aaattgtatc tggtaattct ggcccatgca tttcgcctga
      601 aactgcgata cgaataggca tgaaaagatt tttcccttta atacctgttt ctttttgaac
      661 tgctttaatt tgtgggaaga tattttctgt cacaaattta tcatctgtca tcgcttcaag
      721 ttttgctttg aatgcttcaa gaactgttgg aactgtttca cccgtcatga cttcgcgctc
      781 tgcttctgtc aattctggga aatctgagaa gaaaagatct gtcaatggga taatctcatc
      841 tactgatttc atttgtggtt tatagagctc aactaatttt tcagccttgt cagtcaaacg
      901 gcctgcctcc tctaagaatg gttttgccat ttcaaagatg gtttcaaggt ctgcattctt
      961 gatataatca ttgctcatcc agtctagttt tttctgatca aaggctgctg gtgacttgct
     1021 gaggcggttt tcatcaaaaa gtttaatgag ttcttcacga gagaaaatct catcttcacc
     1081 acctgggttc caaccaagaa gagcaataaa gttaaagact gcttctggaa ggtaaccttt
     1141 ctttcggtaa tcttcgataa attgaagtgt attagtatca cgtttagata acttcttacc
     1201 agtctcagag ttgataatca aggtcatgtg accgaactct ggagcttccc aaccaagaga
     1261 ttcatagacc ataagctgtt ttggtgtatt agcaatatgg tcatctccac ggataacatg
     1321 agagatttgc atatcgtggt catcgatggc aacggcaaag ttgtaagttg ggtaaccgtc
     1381 tttcttttgg ataacccagt caccaccgat attgccacct tcaaattcga tatcgccttt
     1441 gaccatatca tgccacttgt agatacctga ctcattgaca gccaaacgaa cagttgggat
     1501 gatccctgct gcttcacgtt ctgcgatgta agctgctttt tcttcttcac tcataccaag
     1561 gtattcattg atgtagcgtg gtgtttcgcc agctacttct tggcgttcgc gttcagctgc
     1621 caactcttct tctgtaacgt aagatttata ggcttttcct tcagctaata gttggtcaat
     1681 gtatttttga tacaagtcta aacgctcaga ctggcgataa ttctcatgtg attctggact
     1741 ttcatcccaa tccatgccta accagcgaag gttttcaagt tgtgaacgtt caccatcctc
     1801 gacatggcgt ttacggtcag tatcttcgat acggatgaga aatgttccac catgatggcg
     1861 cgcatacaag taattaaaca atgctgtacg agcatttccg atgtgtagta gtcctgttgg
     1921 acttggtgcg taacgtacgc ggatatcttt tgacatagtt tctcctatta tctaggcatc
     1981 tgcctttttg ctttctatat tatatcacaa gtcttgactg agtccaattt ctatggataa
     2041 agagagtaaa aagagtgggt aaaccactct tttcttctat tatagacgtg cgttaagttc
     2101 tttgctcaat tcttcaaatc ctggttttcc aagaagggca aacatgttac gtttataagc
     2161 ttcaacacct ggttggtcaa atgggttgat agcattcaag taacctgaaa gggcaattgc
     2221 caattcgaag aagtagatag tgtaaccaag agtgaaagcg tcttgctctg gaagagtcac
     2281 atacatgttt ggtacatcac catctgtgtg ggcaagaaga acaccgtcag ttgctttttt
     2341 gtttacaaag tcaacgtctt ttccttgaag gtaaccaagt ccgtcaaggt cttcttccaa
     2401 agtaggaata agcacgtttt tacgaggttt gtcaacacgg acaactgttt caaacatgat
     2461 acgagttcct tcttggataa attgaccaag tgagtgcaag tcagttgaga agttggctga
     2521 agttgggtag ataccttttt ggtcttttcc ttctgattca ccagccaatt gtttccacca
     2581 ttctgagaag tattgaagtg atggctcata gtttaccaag atctcagttg catagccttt
     2641 acgataaagg atgttacgaa cagctgcgta ttggtaagct tcgttttcag agattttgtc
     2701 tgaagtgtag tctttgcgag ctgcattcgc accttccata agagctttga tgtcagctcc
     2761 tgatgctgcg attggaagca aaccaacggc tgtcaatact gagaagcgtc caccgatatc
     2821 atctggaaca acaaatgttt cccaaccgtt agcgtctgct tcaaccttaa cagcaccctt
     2881 ttggcggtca gttgttgcat agatacgttt gttagcttct tcttgaccgt atttcttaac
     2941 caagagttct ttaaagacac ggaaagcaat cgctggttca gttgttgtac ctgatttaga
     3001 aattacgttt actgagaagt ctttgtctgc aacatactct accaagtcag caaggtaagt
     3061 agatgagatt gagtttcctg cgtaaaggat ttgtggagct ttgcgttctt cttttgtttg
     3121 caagttagca aaatggtgat tcaagaagtc gattgctgct tttgcaccaa ggtaagatcc
     3181 accaataccg atcacaacca aaacatcgct gtctgacttg atttgctcag cagctttcaa
     3241 gatgcggtca aattcttcgc ggtcgtattt ttcaggaagg tccaaccatc ccaagaagtc
     3301 gctaccagca ccagttcctt tacggatcaa ttcatctgct gctgttactt gtgattgcat
     3361 gtattccact tcatgtggtg caacaaattt gtctaaaact tttgaataat caaatttaat
     3421 atgtgacatg ttcttcctcc aatatttctt cttttctatc ataacgctta ccttcgtttt
     3481 tttcaagttt ttttgtcgaa tttctccaat ttttatcaga attcaaacgt ttgcgtaaaa
     3541 taccacattc taaaaatttt gaaaaaataa aagaaagaac gaccagatgt tccaatcgtt
     3601 acagttcatt caataaatac tcaaataatt ctaaattgcc atcttcttca ttaaccagaa
     3661 actctggatg ccactgtaaa ccgataatgc ggtgctcgtc gatagactca atcgcttcaa
     3721 tagtttggtc tcttgaatca atagcagtta cacggaaatt gggtgccaaa tctttaatgc
     3781 tttgacgatg gactgaattg acctgacttt ctttcccaaa tagcttagcc accacgcttc
     3841 cttctactgt ctcaatagag tgagatgtcc cgaaaggtag tccttgccag tgaccttcga
     3901 tttcttgatt gagggttcca ccaaaggcaa cattgacaag ttggacaccg cgacagattg
     3961 ccataattgg tttattctga cgaagcgctt ccttcaagag tgccaattca aattcgtcac
     4021 ggaccagatt gtaatcatcg ctctcgacgg tctttttctc tccataaaac tgaggatgaa
     4081 cattttggcc tcctgtcaaa atgagtttgt caatcatttc cacataatca cgtacaactg
     4141 actcatcacc aacaggaatg actaaaggga gaccaccgac ttgacgaatg atctctgcga
     4201 atctacaaga tacagatgaa tgaatgattt tgccttctgc gtctacggga catagatttg
     4261 cagcaactcc tacaaccgtt ctagccatga tgcctctcct ttcgaatgct aacgatagtc
     4321 ctatcatatc actcaaaatg actttcgtct aatatgtttt ttttaaggct gtgataaaca
     4381 ttttttatgg acaagaaaaa gctgcccaca taggacaact tctttctcat tcgaaaacaa
     4441 attgattgtg atagagttct gaataaaagc cacctagctt caaaagttca tggtggttac
     4501 cacgttcaat gacttctcca tctttaagga caataatctg atctgcattg agaatggttt
     4561 tcaagcggtg ggcaatgacg aaactagttc tacctgctac aaccacctcc atggcatgct
     4621 gaatcttgct ttctgtcacc gtatctacgt ttgaagttgc ttcatcgaga atgagaactt
     4681 ctggatctgt catcagggtt cgagcgattg aaatcaattg cttctgccct gttgaaaaga
     4741 tgctctggtc atcatcaata agagtatcgt acttatcagg caaactttcg atatagtcgt
     4801 gaatgtgggt tgcttttgct gctacctcaa ccatttcctg actagcatct ggcacaccaa
     4861 atcggatatt gtctcgaatc gttccgctaa acaagaccga atcttgcaat acaattccca
     4921 ccttgcttct aagactatct aagtcatagc cacgaatgtc tttaccatca aaataaatac
     4981 caccagcatc aacatcataa aagcgattga tgaggttcat aatagtcgtt tttcctgaac
     5041 ctgtcggccc aacaactgct gtcatctggc ctttaggggc agaaatgctg acatctttca
     5101 aaataggttt atcaggcaag tatgaaaaat cgatatgact gatttcaaca ctttcttgca
     5161 acttagtgaa ggttggagcc ttttcaggtc ggatttcctc ctctgcatca aacatttcct
     5221 gaattcgttc agctccagta aaggccaact gaaggcttcc ccaactcgct gcaacttgga
     5281 taataggctg gtagtactgc tgtgaaaatt gtgcaaacat aacaatcaaa cctagggctg
     5341 tacttgtttc aatagactta tcattcaaaa gtacagccga accagcaaag atgacgatgg
     5401 ctgtattaat caggctcatc ccattcatga cagggaaaag aattcctgag aacattcttc
     5461 ctttaaaggt tgccttgcgc acgcgctcat tttgttcaag aaatcctgcc atcatatcct
     5521 cttgaattcc ttgcacaatc acggcttttt ggcctgagat gctctcatcc atataggcgt
     5581 tgagcttccc tacctctttc tgctggaggt tggtgtattt gcgtgccatt ttcacgatga
     5641 aaatcagcat aaggaaagcc aatggggtgc tggcaatggt gatgagagcc agcgtcacat
     5701 ttctcgaaaa catgacaaga atcagaccaa tgtataaaac aatattgcac atgacctgaa
     5761 tcaagctttc gttaaaggct tggaggatat tatccaaatc actggtaaaa tgagacagga
     5821 tatcgccatc ttgtcgacgg tcaaagaaag aaaccgtcaa ctgagcaagc ttaccaaaga
     5881 ggcctttgcg catctcgttg gtcgattctg caatcacgcg cgtcatgaga cacatgtata
     5941 ttacactaga gataaataga accaaaacca gcaggccaag attgaccatg attcctgata
     6001 ggctttgcca tacaagttct ggattgccat tttgataagc ttgaactaaa ttggctagct
     6061 gcgtcaccgc ttgtccagaa aagactggaa agagggcttg ggcaaaagtc gccagaacaa
     6121 tcatcaggat gacaactaca aatgagaact tgtaaacctt aaaataatgc caaaaaaatt
     6181 gaactgtctt cattttactc ctccttatat tatatttagc gcagttagct actgccaaag
     6241 cccaagtggt atacttggaa taagccgctg tggattagtt catttcctcc aatcgcttga
     6301 caatttccga aaggatctaa ccacagcttt ttgtttcaat tggtcatgag tttgataacg
     6361 cataaacgtt ttatctcgtg taatgaaaac atcaaacatt acaagaggct cattgacaag
     6421 gcggaaacat gtgtcaatga cttgatggct gagttcaact cgatcatcac gacggttact
     6481 gggattggga atcgtttagg ggcggtcatt ttagccgaga ttcaaaatat tcatgccttt
     6541 gataatcctg ctcaattaca agctttcgct ggactggatt cttctattta tcagtcagat
     6601 cagattgatt tagctggaag aatgatcaaa cggggttccc ctcatctgcg gtaggcactc
     6661 atacaagctg ccaaagcatg ccctcgcttt tcacctgctt ttaaggccta tcttaagact
     6721 aagttagaat aaggaaaaca ttacaatgta gccatcatcc accttacaaa aaaacttatc
     6781 cgaaccctgt tttatatcct aaaaaagagc tgccatttga cgaacaaaaa gtgatgtaat
     6841 ttctgaaatc aacacaggat tacctttgaa aaaatggact ttttcaaggg ctttttgccg
     6901 tgctctaaaa tcatcgccaa atcatcaaat tgaaataaga aataatttag ataaaactat
     6961 tgacttttct tatagtttgt ctttcatttc tgtgtttcat agatttcacg gtaaacggca
     7021 ttgttggcaa ccaagtctgc atgcgtgcct tgaccaatca atcgtccttg atttagaacc
     7081 aagatcttgt ctgcatggac aaccgagcta attttttgag caataataat ggttgtcgtc
     7141 cccttcaagt ccttattcaa agcttcttgc accaagcgct ctgatttggc atccaaggct
     7201 gaggtcgaat cgtcaaaaat cagaatacgt ggattgctga caatcccacg cgcaatcgac
     7261 atcctttgtt tttgtccacc agagaaattg gttccccgtt cttcaactgg actttcaaag
     7321 gttttctcca tacgatgaat gaattcacta gcctgggcaa tattggctgc gcgctccatt
     7381 tcaaatagag tagcatttcc cttcccctgt ctcaagttat ctgcaatcgt tccactaaaa
     7441 agaatggcac gttggagaac gatggaaact gttttacgca gggttccttc actcacttct
     7501 cgaatatcct tgccaccgat tttaatggcc ccgttctgtg gatcaaagag acgtggaatc
     7561 aattgagcca aggttgactt tcctgcacca gtcgctccaa ctacaccaac catttgacca
     7621 ggttcaatag taaagctcac atctttcagc atcggttcat tgtccattgg ataggtaaag
     7681 gtcacatttt caaagctaag gcttccaacc aactcttcat ctgggatatc cttgaaggtc
     7741 atagctggct ctgcgtcaag aatttctcga atacgacgca tggaaatcat ggcacggctg
     7801 acagaatttc ccaaaaatcc aaccataaca atggtaaaga taatctggct taggtaatta
     7861 acaaaagaag cgatggaacc aacaacagac ggatccgact gaaccattcc cgcgaccagc
     7921 caaatagaga ggaagaccgc cccgtaacca accaacatca taaagggttc cactactgaa
     7981 aaggcataac caatgtaaag gttttgacca agaagctcgt ctgagacctc tgtaaactta
     8041 gcaaattgct ctttttcttg gacaaaggac ttgaccacac gaacgccacg taaattttcc
     8101 ttggcaatgg cattgatgcg ctcaagaagg gtttgaaact tggcaaaacg aggccccatc
     8161 attcccatca tgacagcagt caaaccaaaa atcaagacta ccatgagaac aatcacccac
     8221 cacagagaag gtaaggtttg aaccgctagg ataaacgaac cgatgaacaa gaggggaagt
     8281 ctgaaaagaa tctggaaggt catcatgaca acgttctgaa tctggttgat atcatttgtc
     8341 attcgaacga ctagatttcc cgcattaaat tgttcaatat cagcataaga aaaggtttga
     8401 attttacgga aggcatcctc ccgaaggtcg gatgaaactc cttgggcaat ataggctgcg
     8461 aggacaacat tgagtccacc agcaactaga ccgactacgg ccacaccaat caaccaagcc
     8521 ccgatactat aaatagcttc atatttccca gtaaggaggg cgcctaagac ttcctgcaga
     8581 taacgcggtt gcagaagtga actagcaacc atcaaacctg tcatcaggag cgaagccagg
     8641 gcctgccact tgtaggtttt tattttctga atcagcatac tttctcctta aaaaatagac
     8701 aaaagggagc gacaatgcgt cagctccttt tcattctgtt tgtgtgatgt tattctagca
     8761 aaaaagtgga gaattgtcaa agaagtctcc ttgatacagc tagattaact agtgagtctt
     8821 ggttttatag tttctgtttt aactctacta agacattcat aacctgcata ggtgtcatat
     8881 tatacacatc cagtttagct aattctgcta ggataggatg ctcttctgcc ctatcaaaga
     8941 gtgaaatctg ttcagtgaca gcactagttt gtctcatggg aggaggactc tctgttcctt
     9001 gattctctag ctgagtcaaa atcttatccg cccttgctaa aaggtctgct ggcaagccag
     9061 caatcttggc aacatggata ccgtaggatt tatcagctgg tcccggttca atcttgtgaa
     9121 ggaaggtgac ctgcccatcc tgctccaaag ttgccacgtg gacattgacc aagtgttgta
     9181 aactagactc cagactagtc aactcatggt agtgggtcgc aaagagggtc ttagctccga
     9241 tgtgctcatg gatatattcg atgatggact gagcaagagc catcccgtca taagttgcag
     9301 ttccacgccc caattcatca aagagaatga gagagttctt ggtcgcatgc gaaatggcat
     9361 tattggcctc catcatctcc accatgaagg ttgactgacc cgaaaccaag tcatctgctg
     9421 ctccgatacg ggtaaaaatc gcatcaaaaa tcggtaaatg ggcgctttca gcaggaacat
     9481 aggaacccag ctgggccata accgccgtca tggctaactg acgcatatag gtagacttcc
     9541 cactcatgtt tggccctgta accagttgaa tactggtatc ttctgccatc tgaatcgtat
     9601 ttggaatata ggtctgagcc cccataacct tttcaacgac agcatggcgc cctttccgga
     9661 tatcaatttg tgaatcgtca ccaaactcag gtcgaatcaa atgctgggtt tcagccacaa
     9721 ccgccagact ctgtaagaca tcaaccgtcg caattccttg ggctagagct tgtaaacgct
     9781 ggatgtactt gccgacctct tcacgaatgc gcataaatat ttcgtattcg aggttggctg
     9841 acttctcacg cgcctcaagc atatctccct cgatacgggc taattcttcg gttccaaagc
     9901 gttctgagtt tttcagcgtc gccttgcgga aaaagtgggc tggcacattt cccagttgcg
     9961 aattggtcac atgaaaatag tagccatcct ttttattgta gtcaatcttg agcgtgctga
    10021 taccagagtt ttctcgctcc ttagcctcaa tctcagcaat ccagctagtc ccttctctga
    10081 gaacgcaacg atacttgtct aaagtctcat caaatccagt ccggataatt cccccatctg
    10141 taatcacatg aggagcttca ggagcaatcg ctgcgctaat caaactctcc aactcaggga
    10201 ttgcatccag ttgtgcgatg agataggcta gagtaggttg ctccatccct tctaaaatcg
    10261 cacgaatccg tggcacacta gacaaggtag tcgccaactg caagagatcc tttggattgg
    10321 ttttgccaaa agaaacacga ctagccaagc gctcaatgtc ataaacaccc ttgagactgt
    10381 ctgtcaagtc actacgctca aagaaatggt cgagaaagac ctgcactact tcttgacgtt
    10441 ggacgattcg ttccttatca atcaaggggc gatgaatcca agaacgcaag agacgcatcc
    10501 ccatagccgt tttggtttca tccaaaagcc agaaaagact gccttgtttc ttacctgagc
    10561 gagcattctc aaccaaatcc agactagcct tggtcgcata atccatctgc aagaaatcct
    10621 taatttcgta gcggataaca ggtttgaggt ggttcaattc cctcatctga gtccgatgaa
    10681 catactggag cagcttacta gatgccgttt gctccaccgt tgccaatcgc aaatccaata
    10741 aatgaaggtc ttcaaagctt tctttttcat aagagagtac cagattcatc tggcggctga
    10801 ggatttgttc ttcttcctca gacaagtcat aacccaacac cacttctcga gccttgaggt
    10861 tacggatttc cccacaaacc agcgtgaaat ccaaaagacc tgtcacataa aagtcacccg
    10921 tcaccaaatc catataagct aggccaaatt gattgccttc gcggtctatg gaaaccaaaa
    10981 aattattctg actgtccggc ttactgctat cgaccactgt ccctggcgta atgacctgaa
    11041 caacctctcg tttaacaacc ccaactgctt gtttaggatc ttccatctgc tctgcgatag
    11101 ccaccttata accctgctca atcaagacat cgatatactg ttgggcagaa tgatagggaa
    11161 cacccgccat agggatcgga ttgtcggcat tcttgttgcg actcgttaag gaaatttcca
    11221 gaatctgcgc agcattgacc gcatcctcat aaaataattc ataaaaatca cccatccgaa
    11281 agagcaaaaa agcatctgga tattgctttt taatatccac atactgttgc atgccgggtg
    11341 atagcttttc tatcgccatt ttctgtctct ccttttcaaa aataagtctt gagagcaact
    11401 cccaagacct tacttatctt tcatcaaatc tagcaaacga tcttccatga gtttggcaac
    11461 gtgctgatct cgacaaataa ccaataaggt attggcacca gcaactgttc ctaaaatcca
    11521 tttatccttg tttacatcta caatatttgc caaaacagag gcttctccca atttggtatg
    11581 aagcaccaag gtaaactctg ctcttgcaac accttctaaa tgatgagaca aaaattccac
    11641 caaatcaatc ttttctgtct catttactag tacataatac accatatcat ttttcttgac
    11701 cttggtcaag ccgatttcgc gcaaatcacg agacaaggtt gtctgcgtca cacaaacatt
    11761 gtgcgcctcc aaccgatctt gaatttcttt ttgtgtactt aatttctcct cagtaatcat
    11821 tttttttatt aactgatgac gatctctttt tctcataaaa tcctcttgcg tgcatattta
    11881 taactatatt tataaccata ttataccaaa aaaaacaaga gatttcaaaa attttttctt
    11941 ctttctttaa aattgtgtta aaatagtaga aaagtccaaa aaggagctct taatgaatac
    12001 aaaagaattg attgctagcg aattggctag catcattgat agcctggacc aagaggctat
    12061 tttaaagtta ctggaaaccc ctaaaaactc agaaatgggt gacatcgctt tccctgcttt
    12121 ttctcttgcc aaagtcgaac gtaaagcacc acaaatgatt gcggctgaac tggctgaaaa
    12181 aatgaacagc caagcctttg aaaaagttgt cgcaacagga ccttacgtta actttttcct
    12241 tgataaatct gccatttctg ctcaagtatt gcaagctgtt acaactgaaa aagaacacta
    12301 tgctgaccaa aatattggca aacaagaaaa tgttgttatc gacatgtcta gtccgaatat
    12361 cgctaaacca ttttctattg gccacctgcg ttcaactgtt atcggagata gcttgtcaca
    12421 tattttccaa aaaatcggtt atcaaacggt caaggtcaac catttgggag actggggtaa
    12481 acaatttggg atgttgattg ttgcctacaa aaaatggggc gacgaagaag ctgtaaaagc
    12541 tcatccaatc gatgaactcc ttaaactcta tgtccgcatc aacgctgaag ctgaaaatga
    12601 ccctagcttg gatgaagaag cgcgcgaatg gttccgtaaa cttgaaaatg gagatgagga
    12661 agctctcgct ctttggcaat ggttccgcga tgaaagttta gtggaattta accgccttta
    12721 caatgaattg aaggttgaat ttgacagcta taacggagaa gccttctaca atgataagat
    12781 ggatgcagtt gtagacattc tttctgaaaa aggactactt cttgaatcag aaggtgccca
    12841 agttgtgaat cttgagaaat atggaattga acatccagcc ctcatcaaga agtctgatgg
    12901 tgcaactctc tatatcacac gtgacttggc tgcagccctt taccgtaaaa acgaatacca
    12961 atttgctaaa tctatctatg tcgttggtca agaacaatct gcccacttta aacagctcaa
    13021 agctgtcttg caagagatgg gctacgactg gagtgacgac attactcacg ttccttttgg
    13081 tttggttaca aaggaaggga agaagctctc tactcgtaaa gggaatgtca tcttgctaga
    13141 gcctactgtt gcagaggctg ttagccgtgc caaggtccaa atcgaggcta aaaatcctga
    13201 actagaaaac aaagaccaag tagcacatgc tgttggggtt ggagccatta aattctatga
    13261 cctcaaaacc gaccgtacaa atggatacga cttcgaccta gaagctatgg tatccttcga
    13321 gggtgaaact ggaccttacg ttcaatatgc ctacgctcgt atccaatcta tcttacgcaa
    13381 agccgatttc aaaccagaaa cagctggcaa ctatagcttg aatgatactg aaagctggga
    13441 aatcattaaa ctcattcaag acttcccacg tattatcaac cgtgcggcag ataactttga
    13501 accttctatc attgctaaat ttgcaattag cctagctcaa tcctttaaca aatactatgc
    13561 acatacacgt atcttggatg aaagcccaga acgcgacagc cgtctagccc tcagctacgc
    13621 aaccgcagtc gttctaaaag aagcccttcg cttgcttgga gtagaagcgc cagagaagat
    13681 gtaaatcgcc aaagttactt gattgcaaag caatctaagt aactaacgcc aaatcctatt
    13741 cggactttgg ctaggcgctt cactagtttt aggacataaa tatgatcgat ttatgtccta
    13801 aaacgtcgta atcttaaagt tattggaact aaagttccta attgttagac gctagccgct
    13861 tatatgcgaa ctagctaact gcttcactag tcatgacccc taaatataat cgatttagag
    13921 gccatgacgt cgtaaccaga gacacttgcc taaacgcttc actaattcac ctaaccaaat
    13981 aatagacttc ctgcaaaact agaatcctag ttcatgattg ataataccag caatcaaatt
    14041 cattcgtaat ccgaagcgtt tacgatgatt tcgataggtt gttgaaaaca ttttaaacgt
    14101 ttttactttg gcaaagatgt tctcgacctt gcttctctcc ttggatagcg catggttata
    14161 ggcttgatct tcaactgtta gtggcttgag tttgctggat ttacgtgga
//
LOCUS       DAVBOG010000051        13176 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.051, whole genome shotgun sequence.
ACCESSION   DAVBOG010000051 DAVBOG010000000
VERSION     DAVBOG010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13176
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.051"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            276..890
                     /locus_tag="VQ865_001749"
     CDS             276..890
                     /locus_tag="VQ865_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HET3136056.1"
                     /translation="MPTALGYVSIGLACGTIGAPYVTPVEMGLMSLFVYAGSAQFAML
                     ALIVVQAPVAAIAMTVFLINLRLFLLSLHASTYFRHTSLWYNIGMSSILTDETYGVLM
                     GELAHTDKVNPMWMHGNNLNSYVAWFVGTVVGTALGGLLPNPEIFALILSSVVTGKVG
                     SLPQIKWLDFLAVFPTAWVAFRYRNLVGTVLFGVVLIAILRLVF"
     gene            994..1824
                     /locus_tag="VQ865_001750"
     CDS             994..1824
                     /locus_tag="VQ865_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HET3136057.1"
                     /translation="MKKIVKYSSLAALGLVAAGVLAACSGGAKKEGEAASKKEIIVAT
                     NGSPRPFIYEENGELTGYEIEVVRAIFKDSDKYDVKFEKTEWSGVFAGLDADRYNMAV
                     NNLSYTKERAEKYLYAAPIAQNPNVLVVKKDDSSIKSLDDIGGKSTEVVQATTSAKQL
                     EAYNAEHTDNPTILNYTKADFQQIMVRLSDGQFDYKIFDKIGVETVIKNQGLDNLKVI
                     ELPSDQQPYVYPLLAQGQDELKSFVDKRIKELYKDGTLEKLSKQFFGDTYLPAEADIK
                     "
     gene            1978..2832
                     /locus_tag="VQ865_001751"
     CDS             1978..2832
                     /locus_tag="VQ865_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000694494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HET3136058.1"
                     /translation="MKIKKWLGLAALATVAGLALAACGNSEKKADNATTIKIATVNRS
                     GSEEKRWDKIQELVKKDGITLEFTEFTDYSQPNKATADGEVDLNAFQHYNFLNNWNKE
                     NGKDLVAIGDTYISPIRLYSGLNGSANKYTKVEDIPANGEIAVPNDATNESRALYLLQ
                     SAGLIKLDVSGTALATVANIKENPKNLKITELDASQTARSLSSVDAAVVNNTFVTEAK
                     LDYKKALFKEQADENSKQWYNIIVAKKDWETSPKADAIKKVIAAYHTDDVKKVIEESS
                     DGLDQPVW"
     gene            2932..4305
                     /locus_tag="VQ865_001752"
     CDS             2932..4305
                     /locus_tag="VQ865_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HET3136059.1"
                     /translation="MFFPSEQEQIEKFEKDHVAQHYFEVLRTLISKKSVFAQQVGLKE
                     VANYLGEIFKRVGAEVEIDESYTAPFVMAHFKSSRPDAKTLIFYNHYDTVPADGDQVW
                     TEDPFTLSVRNGFMYGRGVDDDKGHITARLSALRKYMQHHDDLPVNISFIMEGAEESA
                     STDLDKYLEKHADKLCGADLLVWEQGTKNALEQLEISGGNKGIVTFDAKVKSADVDIH
                     SSYGGVVESAPWYLLQALQSLRAADGRILVEGLYEEVQEPNEREMALLETYGQRNPEE
                     VSRIYGLELPLLQEERMAFLKRFFFEPALNIEGIQSGYQGQGVKTILPAEASAKLEVR
                     LVPGLEPHDVLEKIRKQLDKNGFDKVELYYTLGEMSYRSDMSAPAILNVIELAKKFYP
                     QGVSVLPTTAGTGPMHTVFDALEVPMVAFGLGNANSRDHGGDENVRIADYYTHIELVE
                     ELIRSYE"
     gene            4298..5359
                     /locus_tag="VQ865_001753"
     CDS             4298..5359
                     /locus_tag="VQ865_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000085652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein"
                     /protein_id="HET3136060.1"
                     /translation="MSRDIIKLDQIDVTFHQKKRTITAVKDVTIHIQEGDIYGIVGYS
                     GAGKSTLVRVINLLQKPSAGKITIDDDVIFDGKVTLTAEQLRRKRQDIGMIFQHFNLM
                     SQKTAEENVAFALKHSGLSKEEKKAKVAKLLDLVGLADRAENYPSQLSGGQKQRVAIA
                     RALANDPKILISDESTSALDPKTTKQILALLQDLNQKLGLTVVLITHEMQIVKDIANR
                     VAVMQDGHLIEEGSVLEIFSNPKQPLTQDFISTATGIDEAMVKIEKQEIVEHLSENSL
                     LVQLKYAGASTDEPLLNELYKHYQVMANILYGNIEILDGTPVGELVVVLSGEKAALAG
                     AQEAIRQAGVQLKVLKGVQ"
     gene            5361..6053
                     /locus_tag="VQ865_001754"
     CDS             5361..6053
                     /locus_tag="VQ865_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004255001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136061.1"
                     /translation="MESLIQTYLPNVYKMGWAGQAGWGTAIYLTLYMTVLSFIIGGFL
                     GLVAGLFLVLTAPGGVLENKVVFWILDKITSIFRAVPFIILLAILSPLSHLIVKTSIG
                     PNAALVPLSFAVFAFFARQVQVVLAELDGGVIEAAQASGATFWDIVGVYLSEGLPDLI
                     RVTTVTLISLVGETAMAGAVGAGGIGNVAIAYGFNRYNHDVTILATIIIILIIFAIQF
                     LGDFLTKKLSHK"
     gene            complement(6083..6652)
                     /locus_tag="VQ865_001755"
     CDS             complement(6083..6652)
                     /locus_tag="VQ865_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000748387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3136062.1"
                     /translation="MKKSILTTLLFAVLYFLCMGIGVLLGNLFDQTGNMFYAPAFTAL
                     VGGSVYMILVAKVPRFGAITTIGLVIAFFFLGTKHGAGSFLPGIICGLLADEVAHLGK
                     YKDKTKNFLSFIIFAFSTTGPILLMWIAPKAYMATLLARGKSQEYIDRIMVAPNPGTV
                     LLFIASIVIGALVGALIGQALSKKFAQKI"
     gene            6787..7401
                     /locus_tag="VQ865_001756"
     CDS             6787..7401
                     /locus_tag="VQ865_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000532354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HET3136063.1"
                     /translation="MGRFLDFVFNRFFLGMIATAFFWLLTLAGGIILGLAPASATLMS
                     LYAEHGYSFREYSLKEAWSLYKQNFVSSNLIFYSFLGVGLVLTYGLYLLVQLPHQTIV
                     HLIATLLNVLVVALIFLAYTVSLKLQVYFALSYRNSLKLSLIGIFMSLAAVAKVLLGT
                     VLLVAIGYYMPALLFFVGIGMWHFFISDMLEPVYEIIHEKLATK"
     gene            7403..9049
                     /locus_tag="VQ865_001757"
     CDS             7403..9049
                     /locus_tag="VQ865_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013670288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3136064.1"
                     /translation="MKQFWLHTLLRTYSSVMIIIIASFAILLSYADWDSREKEAQRVA
                     QRVTARTVSEIEYYHRESTQIAQALVENQARIEGIYKYFSLSMPDYFYWQLERKASPY
                     ISVSLYENVDDLYVRNDFVTGVAIAFQDYKEVYVSTKDKRSGEKIRAEDFKPAGNSFA
                     IPVSDPVSDQDLGVIYISLDPAVLYHAIDNTRGNTPMAVTVTSPFDTEIFHIGETVDK
                     ESENWLVGLTSHGYQVQVAVPKNFVLQGTVTSSALIVGLSLLFIVILYLTLRQTFANY
                     QKQVVDLVESIQVIAQGEEGRRIDISEKDQELLLIAETTNDMLDRLEKNIHDIYQLEL
                     SQKDANMRALQAQINPHFMYNTLEFLRMYAVMQSQDELADIIYEFSSLLRNNISDERE
                     TLLKQELEFCRKYSYLCMVRYPKSIAYGFKIDPELENMKIPKFTLQPLVENYFAHGVD
                     HRRTDNVISIKALKQDGFVEILVVDNGRGMSAEKLANIREKLSQRNFEHQASYSDQRQ
                     SIGIVNVHERFVLYFGDRYAITIESAEQAGVQYRITIQDE"
     gene            9061..10347
                     /locus_tag="VQ865_001758"
     CDS             9061..10347
                     /locus_tag="VQ865_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000278884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3136065.1"
                     /translation="MYKVLLVDDEYMVTEGLKRLIPFDKWDMEVVATASHADEALEYV
                     QENPVDVIISDVNMPDKTGLDMIREMKEILPDAAYILLSGYQEFDYVKRAMNLSVVDY
                     LVKPVDKVELGNLLEKIAGQLGERGKKSQTLSQELDEAGFVSYLGDKENWWIGLSKEK
                     QGSFTIPYYVLGQAWQIFISDQPLDGLVVTPFEAPYQEHFERWKLNAEKTLFYGSVNL
                     QQSESLFAYYEPIYRVIIQGNLNQIVEELNLLEKVVLENTPRIPITKQLFIQFVMDVF
                     HLFEHLKADDMTDIVKTIHAIQSFDELVSYIKETLISFFGQYRMNENVVSVLEVIGRD
                     YQKELSLKDISKALFINPVYLGQLIKRETDSTFAELLNKQRIKAAQQLLLSTSDSIED
                     ICYAVGYSNLGYFYKVFRKLCGKSPKAYRKQVETIL"
     gene            10399..10932
                     /locus_tag="VQ865_001759"
     CDS             10399..10932
                     /locus_tag="VQ865_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136066.1"
                     /translation="MKKKPIYLWVLLILSALISVPSLFGIVSPLPSKEALRVAQKQVA
                     GVNAQQLEDQLNYTYRVAEASHSIFNVALIVLSTILVVVAIVFLVRKNLQYANYTYVG
                     YVLLAIIGSIYGYVGLQDAVQLVQDESMRLTVSIGSKAVSIFYIVINVLFLALVFYKM
                     WRQQKALAEEEETEELA"
     gene            11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ865_001760"
     CDS             11010..11480
                     /gene="nrdI"
                     /locus_tag="VQ865_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HET3136067.1"
                     /translation="MKTISLVYISLSGNTESFVTRLKDYLLSQYKGIEVQKIHIKDLV
                     KEGKNFYEMDHLYVAFLPTYLEGGNGVDNGDVEILTTPVGDFIAYGNNASKCFGVVGS
                     GNRNFNNQYCLTAKQYSQRFGFPVLADFEMRGMLEDIKHVAAIIADLYELEKEN"
     gene            complement(11773..13035)
                     /locus_tag="VQ865_001761"
     CDS             complement(11773..13035)
                     /locus_tag="VQ865_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent metal cation transporter"
                     /protein_id="HET3136068.1"
                     /translation="MSQAISLNQSTWASKLKAMGPGILMATAAVGGSHIVSSTQAGGS
                     YGWSLLLLVILANVFKYPFFRFGAEYTADTGKTLVEGYAEKGKLYLWIFFILNVFSAM
                     VNTAGVAILCSAIIASAFPMIGLSITQWSLILVAIIWAMLLFGGYKLLDGMVKWIMSA
                     LTIATVLAVIIAAVKHPEYSSDFVEKTPWQMAALPFIVSLLGWMPAPIEISAINSLWS
                     AEKRKTVNFNTEDALFDFNTGYIGTAILAVFFVALGALIQYPTGQAVEAASAKYISQF
                     VGMYASVLGEWSRYLITFIAFLCIFGTVITVIDGYSRVNQESLRLLISQKEDNRKSLN
                     IWMTITAIIGIVIIKFFAGQVSTMLRFAMIGSFLTTPFFALLNYALVTRENKNLPSWL
                     KHLAIAGLIFLFGFAIFFIYALAIGKAG"
BASE COUNT         3901 a         2453 c         3007 g         3815 t
ORIGIN      
        1 tatcttattt caatctgcta tataatagtc catgctatgg ctggattctt ttcagtctac
       61 ttatactctt cgaaactctc ttcaaaccac gtcagcttca ccttgccgta gtacggttac
      121 tgacttcgtc agttctatcc acaacctcaa aacggtgttt tgagcaacct gcggctagtt
      181 tcctagtttg ctctttgatt ttcattgagt attattaaga caatatgagg agaaagatga
      241 aagaaaaagg attttaggag ggggcgcagg cagccatgcc aacggctctt ggctatgtca
      301 gtatcggcct ggcctgtggg actatcggtg cgccctatgt gacacctgtt gagatgggct
      361 tgatgagtct ctttgtttat gctgggagtg cccagtttgc catgttggca ctgattgtgg
      421 ttcaagctcc tgtggcagct attgctatga cggtttttct aatcaacttg cgtctctttt
      481 tgttgagttt acacgcatcg acttatttcc gtcataccag tctttggtac aatatcggta
      541 tgtctagtat cttgacagat gagacctatg gcgttttgat gggtgaattg gcccatacag
      601 acaaggtaaa tcctatgtgg atgcacggaa acaatcttaa cagctatgtg gcttggtttg
      661 tggggacagt agtcggaacg gctctgggtg gcctgctacc aaatccagaa atctttgcct
      721 tgattctttc aagcgtagtg acaggtaagg ttgggagcct tcctcaaatt aaatggctag
      781 acttcttagc cgtctttcca acagcttggg tagcctttcg ctaccgcaat ctagtcggaa
      841 cagttctctt tggagtggtc ttgattgcca tcttgcgttt ggtcttttaa attacccata
      901 aaaaaaactt atcacagaga tagatatcat ataatggcgt aaatgctctt tttctgttaa
      961 gattataagg tattctattt tggaggaaat gacatgaaaa aaatcgttaa atactcatct
     1021 cttgctgccc taggacttgt tgctgcaggt gtgcttgcgg cttgctcagg gggtgctaag
     1081 aaagaaggag aagcagctag caagaaagaa atcatcgttg caaccaatgg atcaccaagg
     1141 ccatttatct atgaagaaaa tggcgaattg actggttacg agattgaagt cgttcgcgct
     1201 atctttaaag attctgacaa atatgatgtc aagtttgaaa agacagaatg gtcaggtgtc
     1261 tttgctggtc ttgacgctga ccgttacaat atggctgtca acaatcttag ctacactaaa
     1321 gaacgtgcgg agaaatacct ctatgccgca ccaattgccc aaaatcctaa tgtccttgtc
     1381 gtgaagaaag atgactctag tatcaagtct ctcgatgata tcggtggaaa atcgacggaa
     1441 gtcgttcaag ccactacatc agctaagcag ttagaagcat acaatgctga acacacggac
     1501 aacccaacta tccttaacta tactaaggca gacttccaac aaatcatggt acgtttgagc
     1561 gatggacaat ttgactataa gatttttgat aaaatcggtg ttgaaacagt gatcaagaac
     1621 caaggtttgg acaacttgaa agttatcgaa cttccaagcg accaacaacc gtacgtttac
     1681 ccacttcttg ctcaaggtca agatgagttg aaatcatttg tagacaaacg catcaaagaa
     1741 ctttataaag atggaactct tgaaaaattg tctaaacaat tcttcggaga cacttatcta
     1801 ccggcagaag ctgatattaa ataatttctt gaaatcatcc attctgagta aggtgggtgg
     1861 tttctcagtt tttagggata tagttttaaa ctatatatct gactatctaa taacaatttg
     1921 tgaaatcaaa caaattgtga gatactagta cggtattatt tttaaggaga aagaatcatg
     1981 aaaatcaaaa aatggcttgg tctagcagcc cttgctacag tcgcaggttt ggctcttgca
     2041 gcttgcggaa actcagaaaa gaaagcagac aatgcaacaa ctatcaaaat cgcaactgtt
     2101 aaccgtagcg gttctgaaga aaaacgttgg gacaaaatcc aagaattggt taaaaaagac
     2161 ggaattacct tggaatttac agagttcaca gactattcac aaccaaacaa agcaactgct
     2221 gatggcgaag tagatttgaa cgctttccaa cactataact tcttgaataa ctggaacaaa
     2281 gaaaacggaa aagaccttgt agcgattgga gatacttaca tctctccaat ccgcctttac
     2341 tcaggtttga atggaagtgc caacaagtac actaaagtag aagacatccc agcaaacgga
     2401 gaaatcgctg taccgaatga cgctacaaac gaaagccgtg cgctttactt gcttcaatca
     2461 gctggcttga ttaaattgga tgtttctgga actgctcttg caacagttgc caacatcaaa
     2521 gaaaatccaa agaacttgaa aatcactgaa ttggacgcta gccaaacagc tcgttcattg
     2581 tcatcagttg acgctgccgt tgtaaacaat accttcgtta cagaagcaaa attggactac
     2641 aagaaagcac ttttcaaaga acaagctgat gaaaactcaa aacaatggta caacatcatt
     2701 gttgcgaaaa aagattggga aacatcacct aaggctgatg ctatcaagaa agtaatcgca
     2761 gcttaccaca cagatgacgt gaaaaaagtt atcgaagaat catcagatgg tttggatcaa
     2821 ccagtttggt aataagaaac agggaggtgg gagagaaaat tccacctctt gcttttgtat
     2881 agagtataga ttgtaaagaa gactattcgt tcatagaaag gtagagagaa tatgtttttt
     2941 cctagcgaac aagaacagat tgaaaaattt gaaaaggatc atgtagccca gcattatttt
     3001 gaggttttgc gtaccttgat ttctaagaaa tcagtctttg cccagcaggt tggactcaag
     3061 gaagtcgcaa actatctggg tgagattttc aagcgtgttg gagctgaagt ggagattgat
     3121 gagagctata cagcgccctt tgtcatggca catttcaaga gttcgcgtcc agatgccaag
     3181 accttgattt tctataacca ctatgacact gtgccagcgg atggggatca ggtctggaca
     3241 gaggatcctt ttacgctttc ggtccgcaat ggcttcatgt atgggcgtgg ggttgatgac
     3301 gacaagggtc atatcacagc tcgcttgagt gctttgagaa aatatatgca gcaccatgat
     3361 gatttacctg tcaatatcag ctttatcatg gagggagcgg aggaatcggc ttcaacagac
     3421 ctagataagt atttggaaaa gcatgcagac aaactctgtg gggcggattt gttggtctgg
     3481 gaacaaggga ccaaaaatgc cttggaacag ctggaaattt ctggtggcaa taagggaatt
     3541 gtgacctttg atgccaaggt aaaaagcgct gatgtggata tccactcgag ttatggtggt
     3601 gttgtggaat cagctccttg gtatctcctc caagccttac agtctcttcg tgctgcggat
     3661 ggccgtatct tggttgaagg cttgtacgaa gaagtacaag agcccaatga acgagaaatg
     3721 gccttgctag aaacttatgg tcaacgaaac ccagaggaag ttagtcggat ttatggattg
     3781 gagttgcctc tcttacagga ggagcggatg gcctttctaa aacgtttctt tttcgagcca
     3841 gcgcttaata tcgaaggaat ccagtctggt tatcaaggtc agggtgttaa gactatttta
     3901 cctgcagaag ccagtgcaaa gctagaggtt cgtctggttc cgggcctaga accgcatgat
     3961 gttctggaaa aaattcggaa acaactagac aaaaatggct ttgataaggt agaattatac
     4021 tataccttgg gagagatgag ctatcgaagc gatatgagcg caccagccat tctcaatgtg
     4081 atcgagttgg ccaagaaatt ctatccacag ggtgtttcag tcttgccgac gacagcgggg
     4141 acaggaccta tgcatacggt ctttgatgcc ctagaggtac caatggttgc attcggtcta
     4201 ggaaatgcca atagccgaga ccacggtgga gatgaaaatg tgcgaatcgc tgattattac
     4261 acccatatcg aattagtaga ggagctgatt agaagctatg agtagagata ttatcaagtt
     4321 agatcagatc gatgtgactt ttcaccaaaa gaagagaacc attacagcgg ttaaggatgt
     4381 gaccattcac atccaagaag gggatatcta cggaatcgtt ggatattctg gagcaggaaa
     4441 atcaaccctt gtacgggtga ttaacctctt gcaaaaacca tctgcaggga aaattaccat
     4501 tgacgacgat gtgatttttg atggtaaggt caccttgacg gcagagcagt tgcgtcgtaa
     4561 acgtcaagat atcgggatga ttttccagca ttttaacctg atgagccaaa agacagcaga
     4621 ggagaatgta gcctttgccc ttaaacactc tggactcagc aaggaagaaa agaaggctaa
     4681 agtagctaag ttgttggact tggttggttt ggcagatcgt gctgaaaact acccttcaca
     4741 attatctgga gggcaaaaac agcgtgtggc aattgcgcgt gccttggcca atgatccaaa
     4801 aatcttgatt tcagacgagt caacttctgc ccttgaccct aagacaacca agcagatttt
     4861 ggccttgttg caagatttga accaaaaatt aggcttgact gttgtcttga ttacgcatga
     4921 aatgcagatt gtcaaagaca ttgccaaccg tgttgcagtt atgcaggatg ggcatttgat
     4981 tgaagagggt agtgtgcttg aaatcttctc aaaccctaaa caacctttga ctcaagactt
     5041 tatctcaaca gctacaggta ttgacgaagc catggtcaaa atcgagaagc aagaaatcgt
     5101 ggaacacttg tctgaaaaca gtctcttggt gcaactcaag tacgctggag cttcaacaga
     5161 cgagccactt ttgaatgaat tgtacaagca ttaccaagta atggctaata ttctctatgg
     5221 gaatatcgaa attctcgatg gtactcctgt tggagaattg gtggtggttt tgtcaggtga
     5281 aaaagcagcg ttggcaggtg cccaagaagc cattcgtcaa gcaggtgtac aactaaaagt
     5341 attgaaggga gtacagtaag atggaatcat tgattcaaac ctatttacca aatgtctata
     5401 agatgggttg ggctggtcag gcaggctggg gaacggctat ctacttaact ctttatatga
     5461 cagttctttc cttcattatc ggaggcttct tggggctagt ggcaggtctc tttctcgtct
     5521 tgacagcgcc aggtggtgtc ttggagaata aagtcgtatt ctggatttta gacaaaatta
     5581 cctcaatttt tcgtgcggtt ccctttatca tcctcttggc aatcttgtca ccactttctc
     5641 acttgattgt taaaacaagt atcgggccaa atgcagccct tgtcccactt tcttttgcag
     5701 tctttgcctt ctttgcccgt caggtgcagg ttgtcttggc tgaattggat ggcggtgtca
     5761 ttgaggcggc tcaagcgagc ggagcgactt tctgggacat cgtgggtgtt tacctatcag
     5821 aaggtcttcc agatttgatc cgtgtgacga ctgtgacctt gatttccctt gttggggaaa
     5881 cagctatggc cggtgcggtt ggagctggtg gtatcggtaa cgtagccatc gcttatggat
     5941 ttaaccgcta caatcacgat gtgaccatct tggcaaccat tattatcatt ttgattatct
     6001 ttgcaatcca attcttggga gatttcttga ctaagaaatt gagccataaa taaaaaagag
     6061 ccgcgtggct ctttttaact gatcagattt tctgtgcaaa ttttttactc aaggcttgtc
     6121 caatcaaagc acccactagg gctccgatga caatacttgc gataaataga aggacagttc
     6181 cagggtttgg agcgaccatg atacggtcga tatattcttg ggattttcct cttgccagaa
     6241 gagtagccat ataggctttg ggcgcaatcc acataagcaa gattggtcct gttgtactaa
     6301 aggcgaaaat aatgaaagaa aggaagttct ttgttttgtc cttgtatttt cctaaatgag
     6361 ctacttcatc tgctaggagg ccacagataa ttccaggaag gaaggaacca gcaccgtgtt
     6421 tagttcccaa gaaaaagaag gcaatgacaa ggccgatagt ggtaatggct ccaaagcgcg
     6481 gaacttttgc gactaggatc atatagacgc taccgccgac aagggcagta aaggcaggcg
     6541 cataaaacat gtttccagtt tggtcaaaga gattgcccaa aaggacacca atccccatgc
     6601 agaggaagta aagaactgca aaaagcagtg tagttaagat agatttcttc atgaattgtc
     6661 tcctgataat tttttcacaa ttctcatttt accatggttt ggtgggattg taaatggata
     6721 ctagaagttt ttgaaaacgc ttgaaatatg atataatggt ttcatagtta tttttagggg
     6781 aatatcatgg gtagattttt agactttgtc tttaatcgtt tctttttagg gatgattgcg
     6841 acagccttct tttggctatt aactttagca ggagggatta tccttggtct agcgccggct
     6901 agtgccacct tgatgagctt atatgcagaa catggttata gctttcggga atacagtttg
     6961 aaggaggctt ggtctcttta caagcaaaat tttgtctcaa gcaacctgat tttctatagc
     7021 tttttaggtg tgggtctagt tttgacctat ggtttgtatc tcttggtgca attgcctcat
     7081 cagaccattg ttcatttgat tgcgaccctt ttgaatgtct tagtagttgc cctgatcttt
     7141 ttggcttata cagtatcttt aaaattacaa gtttattttg ccttgtccta tcgaaatagt
     7201 ctcaaattat ccttgattgg catctttatg agtctagcag ctgtggccaa ggttctcctt
     7261 gggactgtgc tacttgtagc aattggttac tatatgcctg ccctgctatt ttttgtagga
     7321 attgggatgt ggcatttctt tatcagtgat atgttggaac ctgtctatga aatcatccat
     7381 gaaaaattgg cgacaaaata gaatgaagca gttttggcta catacgcttc taagaaccta
     7441 tagttcagtg atgatcatta tcattgcgag ttttgcaatc ttactctctt acgctgactg
     7501 ggattcacgt gaaaaggaag cccagagagt agcccagcgt gtaactgcta gaacagtgag
     7561 tgaaattgaa tattaccata gagagtcaac ccagatagct caggctttag ttgaaaatca
     7621 agctcgtatt gagggaatct ataaatactt tagccttagc atgccagact atttttactg
     7681 gcaattagag cggaaagctt cgccttatat atcagtctct ctgtatgaaa atgttgatga
     7741 cctctatgtt cgaaatgatt ttgtaactgg agtggccatt gcttttcaag attacaagga
     7801 agtctatgtt tctactaaag acaaacgtag tggagaaaaa atcagggctg aggatttcaa
     7861 accagcagga aatagttttg ccattccggt gtcagatcca gtgtcagatc aagatttagg
     7921 agtgatttac atctccttgg atcctgctgt tttataccat gccattgata atactagagg
     7981 taatactccg atggcagtaa cagtgacctc accttttgat acggagattt ttcatattgg
     8041 tgagacagtt gataaggaga gtgaaaattg gctagttggc ttaacttctc atggatatca
     8101 ggttcaggtg gcagttccta aaaactttgt tttacaagga acagtgacta gctctgcttt
     8161 gattgtgggt ttgagccttc tctttattgt cattctttat ctgactttga ggcagacttt
     8221 tgctaattac caaaagcagg tagtggattt agtagaatcc attcaagtca ttgctcaagg
     8281 cgaagagggt cgtcggattg acatttccga gaaagatcag gaattactcc taatcgcgga
     8341 gacgaccaat gatatgttgg atcgattgga aaagaatatc catgatattt accagttaga
     8401 gcttagtcaa aaagatgcta atatgcgagc cttgcaggcg caaatcaatc ctcattttat
     8461 gtataatacg ctggagttct tgcgcatgta tgcagttatg cagagtcaag atgagttggc
     8521 agatatcatt tatgaattca gtagtctctt gcgtaacaat atttccgacg aaagagagac
     8581 cctcctcaaa caggaattag aattttgccg taaatacagc tatctctgca tggttcgcta
     8641 tcccaagtcc attgcctatg gtttcaagat agatccagag ttagagaata tgaagattcc
     8701 taagttcacc ttgcaaccgc tggtagaaaa ttatttcgcg catggtgttg accacaggcg
     8761 gacagataat gtgattagca tcaaggctct taaacaggat ggttttgtgg aaattttggt
     8821 ggtcgataat ggtagaggaa tgtcggctga aaagttggca aatatccgag aaaaattaag
     8881 tcagagaaat tttgaacacc aagccagcta cagtgatcaa aggcagtcta tcgggattgt
     8941 caatgtacac gagcgttttg tgctctattt tggagaccgc tatgccatta ctatagagtc
     9001 tgcagagcaa gccggtgttc agtatcgtat tacaattcaa gatgagtaga aagggagaaa
     9061 atgtataaag tattattagt agatgatgag tacatggtga cagaaggtct gaagcgtttg
     9121 attccctttg ataagtggga tatggaggtc gtcgcaacag ccagtcatgc cgatgaagct
     9181 ctagaatatg ttcaggaaaa tcctgtcgat gtcatcattt ccgatgtcaa tatgccagac
     9241 aaaacagggc ttgatatgat tcgggagatg aaagagatct taccagatgc tgcctatatc
     9301 ctgctctcag gttatcagga gtttgattat gtaaaaagag caatgaacct tagtgtggtg
     9361 gactatttgg tcaaacctgt tgataaggta gagctgggaa atctgctgga gaagattgca
     9421 ggtcagctcg gcgagagagg gaagaaaagt cagactctta gtcaagaatt agacgaggct
     9481 ggatttgtta gttatttagg ggataaggag aattggtgga taggtctatc caaggaaaaa
     9541 caaggttcct tcaccattcc ctactatgtc ttgggtcaag cctggcagat tttcatttct
     9601 gaccaacccc tagatggttt agtcgttaca ccttttgaag ctccttatca agaacatttt
     9661 gaacgctgga agctgaatgc tgagaaaacc ctcttttacg gttctgtaaa tctgcagcag
     9721 tctgagagtc tctttgccta ttacgaaccg atttataggg ttatcattca gggaaatctc
     9781 aatcaaatcg tagaagagtt aaatctcttg gagaaggtag ttcttgaaaa tacgccgcga
     9841 attccgatta ctaaacagct ttttatccag tttgtcatgg atgtcttcca tttatttgaa
     9901 catctcaaag ctgatgatat gacggacatt gtcaaaacca ttcatgctat tcaatccttc
     9961 gatgaattgg tttcttatat caaggaaact ctgatcagct ttttcggtca ataccgtatg
    10021 aatgaaaatg tggtcagtgt gctggaagtc attggtcgtg attaccaaaa agagctttcc
    10081 ctcaaggata tcagtaaggc cctctttatc aatcctgtct atctagggca gttgattaag
    10141 cgtgaaaccg attcgacctt tgcagagtta ctaaacaaac aacgtattaa ggctgcccag
    10201 cagctcttgc tttcaaccag tgacagtatc gaagatattt gttatgctgt tggttacagt
    10261 aaccttggat atttctataa agttttccga aaattgtgcg gaaaatcgcc aaaagcctac
    10321 cgaaaacagg tagaaactat actataagat ttgtattcct ttacaaaatg tgctataata
    10381 ttatcaggag gttctatcat gaaaaagaaa ccaatttatc tatgggtctt gctaatcttg
    10441 tctgccctta tttcagttcc gtctctgttt ggaattgtga gtcccttgcc tagtaaagaa
    10501 gcccttcgtg ttgctcagaa acaagttgca ggggtcaatg ctcagcaatt agaagaccag
    10561 cttaattata cctatagagt agcagaagca tctcattcta tttttaatgt tgctttgatt
    10621 gtgctatcta ctattttagt ggtcgtagcg attgtcttcc ttgttcgtaa aaatttgcaa
    10681 tatgcaaact atacttacgt tggctatgtt ttgttagcta ttattggttc gatttatggc
    10741 tatgttggtt tacaagacgc tgtgcagttg gttcaagatg agagcatgcg tttgacagtg
    10801 agtattggtt caaaagctgt tagcattttc tatatcgtca tcaatgttct cttcctagcc
    10861 cttgtcttct ataagatgtg gcgacaacag aaagccttgg cagaagaaga ggaaacagaa
    10921 gagcttgcct aagtattgac aaaaaagaac tatcaagata caatcttggt agttattttt
    10981 tgattataga taaaatcatg gaggtacata tgaagacaat ttctttagtt tatattagtt
    11041 tgagtggcaa cactgaaagt tttgtgacgc gcttgaaaga ctatctcttg tcccagtaca
    11101 aagggattga ggttcaaaag attcatatca aggatttggt caaggaaggc aaaaatttct
    11161 atgaaatgga ccatctctat gtcgcttttt tgccgaccta tctcgaaggt gggaatggcg
    11221 tggataacgg agatgttgag attttgacaa caccggtggg agattttatt gcctatggta
    11281 acaatgctag taagtgtttt ggtgtggttg ggtcaggaaa tcgtaacttt aataaccaat
    11341 actgcctaac agccaagcaa tacagtcaac gctttggctt ccctgtattg gctgactttg
    11401 aaatgcgagg catgctggaa gatatcaaac atgtcgcagc tattatcgca gatttgtatg
    11461 agttggaaaa ggagaattaa tactcaatga aaatcaaaga gcaaactagg aagctagtcg
    11521 caggttgctc aaagcacagc tttgaggttg cagatagagc tgacgtggtt tgaagagatt
    11581 ctcgaatagt ataaagttct tataagaggt ggttgaagtt gttcaactgt tttttgagta
    11641 taaacagtct ttaagaacgt aaaaaagcat aagttcaggt cttcaaaacc ttgttcttat
    11701 gctttttatc atagaaatat ttgctgaatt ttctcttgaa atgaaacctt atcttcatct
    11761 cgcgcttgtc ccttaccctg cttttccgat tgcgagtgcg tagataaaga agatggcgaa
    11821 gccaaagagg aaaatcaatc ccgcaatggc aaggtgtttg agccaagaag gaagattttt
    11881 gttttcacgc gttaccaagg cgtaattcaa aagagcaaag aaaggtgttg tcaggaaaga
    11941 tccaatcatg gcaaagcgga gcatggttga aacctgacca gcgaagaact tgataatgac
    12001 gataccgatg atagcagtga tggtcatcca gatgttcaaa gatttacgat tgtcctcttt
    12061 ttgactgatt agcagtcgga gagattcctg attaacgcga gaatagccat cgataacagt
    12121 tataactgtt ccaaagatac agaggaaggc aataaaggta atcaagtaac gggaccattc
    12181 gccaagaaca gaggcataca tgcccacgaa ttgagagatg tatttggctg aagcagcttc
    12241 aaccgcctgc cctgtaggat actgaatcag tgctcccagt gccacaaaga agacggctag
    12301 gatagctgtt ccaatataac cagtgttaaa gtcaaacaga gcgtcttctg tgttaaagtt
    12361 gacggtcttt ctcttttcag ctgaccaaag tgaattgata gctgaaattt caataggagc
    12421 cggcatccat cctaggaggg agacgatgaa gggcagagct gccatttgcc aaggtgtctt
    12481 ctcgacaaaa tcagaactgt attctggatg cttgaccgct gctatgataa ctgccagaac
    12541 agtcgcaatg gttaaggcag acataatcca tttgaccatg ccgtctaaaa gtttgtagcc
    12601 tccaaagagt agcatagccc aaatgattgc aacgagaatg agggaccact gagtaatgct
    12661 aagtccaatc attgggaagg cactggcgat gatagctgag cacagaatgg caacaccagc
    12721 cgtgttgacc atagccgaaa agacattgag gataaagaaa atccagagat agagttttcc
    12781 tttttcggca taaccttcaa ccaaagtctt tccagtatca gctgtgtatt cagcaccaaa
    12841 acggaaaaat ggatatttaa agacattggc taagatgact aagagaagta gagaccaacc
    12901 gtaagaaccg ccagcttgag ttgaggatac aatgtgggaa cctccaacag cggcagttgc
    12961 cattaggatt ccaggcccca ttgcttttag cttgcttgcc caggttgatt gatttaagga
    13021 aatagcttgc gacatgataa atactccttt ttgaattttc agaataatct gtatatgtaa
    13081 tctatattct acaaaaaatt ttggaaaaat gcaagaatat tttgaaaaaa gatagaaaat
    13141 ttacaaagaa aatctgaaat aactgttatg atatag
//
LOCUS       DAVBOG010000052        13159 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.052, whole genome shotgun sequence.
ACCESSION   DAVBOG010000052 DAVBOG010000000
VERSION     DAVBOG010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 13159)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13159)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13159
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.052"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..367
                     /locus_tag="VQ865_001762"
     CDS             <1..367
                     /locus_tag="VQ865_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HET3136069.1"
                     /translation="PNLEQVQTMLEQTFTEKHYENTILHSDQGWQYQHDSYHQFLESK
                     GIQASMSRKGNSPDNGMMESFFGILKSEMFYGYEKSFQSRKQLEQAIVDYIDYYNNKR
                     IKVKLKGLSLVQYRTKSFG"
     gene            complement(442..972)
                     /locus_tag="VQ865_001763"
     CDS             complement(442..972)
                     /locus_tag="VQ865_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase family protein"
                     /protein_id="HET3136070.1"
                     /translation="MLDEKRKNYVEDKRQNFPSLPSWKMDLFSEEEKRIYFQTTCEVS
                     SKDSAINKYKIEKIIKRSNKGNVYRAIRKSDGQKVIIKQSRPFVNYDAEGEWTALDDI
                     KNEAYMLKKLADKSYTTNLTDEFYIVDDYFLVQEQVDGLNFEEFIRETEHSLNIREKT
                     LDNIVNIVSDIHKLGI"
     gene            complement(966..1434)
                     /locus_tag="VQ865_001764"
                     /pseudo
     CDS             complement(966..1434)
                     /locus_tag="VQ865_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001847907.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            1984..2661
                     /locus_tag="VQ865_001765"
     CDS             1984..2661
                     /locus_tag="VQ865_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000624068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HET3136071.1"
                     /translation="MISKRLELVASFVPQGAILLDVGSDHAYLPIELVERGKIESAIA
                     GEVVEGPYQSAVKNVEAHGLEEKIQVRLANGLAAFEEEDRVSVITIAGMGGRLIARIL
                     EEGLDKLANVERLILQPNNREDDLRIWLQDHGFQIVAESILEEAGKFYEILVVEAGQM
                     KLSASDVRFGPFLSKEVSPVFVQKWQKEAEKLEFALGQIPEKNLEERQVLVDKIQAIK
                     EVLHVSK"
     gene            2648..3445
                     /locus_tag="VQ865_001766"
     CDS             2648..3445
                     /locus_tag="VQ865_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000881127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HET3136072.1"
                     /translation="MLASEVIQAYEAFCPQEFSMEGDSRGLQIGTLDKGIQRVMVALD
                     IREETVAEAIEKGVDLIIVKHAPIFRPIKDLLASRPQNQIYIDLIKHDIAVYVSHTNI
                     DIVENGLNDWFCQMLGIEETTYLQETGPERGIGRIGNIQPQTFWELAQQVKQVFDLDS
                     LRMVHYQENDLQKPISRVAICGGSGQSFYKDALAKGADVYITGDIYYHTAQDMLSDGL
                     LALDPGHYIEVLFVEKIAALLTQWKEKKGWELEILPSQASTNPFRHI"
     gene            3462..4565
                     /locus_tag="VQ865_001767"
     CDS             3462..4565
                     /locus_tag="VQ865_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HET3136073.1"
                     /translation="MKKVAIIGAGIVGATAAYYLSRESDLEVTVFDHEQGQATKAAAG
                     IISPWFSKRRNKAWYKMARLGADFYVDLLADLEKSGQKIDFYQRSGVFLLKKDESKLE
                     ELYQLALQRREESPLIGQLAILDQASANELFPGLQGFDRLLYASGGARVDGQLLVTRL
                     LEASHVKLVKEKVTLTLLSSGYQIGEEVFDQVILATGAWLGDMLEPLGYEVDVRPQKG
                     QLRDYQLAQDMEDYPVVMPEGEWDLIPFAGGKLSLGATHENDMGFDLTVDEPLLQQME
                     EAALPHYPVLARATSRAERVGIRAYTSDFSPFFGQVPELAGVYVASGLGSSGLTTGPI
                     IGYHLAQLIQDKELTLDPLNYPIENYVKRVKSE"
     gene            4866..5885
                     /gene="galE"
                     /locus_tag="VQ865_001768"
     CDS             4866..5885
                     /gene="galE"
                     /locus_tag="VQ865_001768"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HET3136074.1"
                     /translation="MQEKILVTGGAGFIGTHTVIELIQAGHQVVVVDNLVNSNRKSLE
                     VVERITGVEIPFYEADIRDTVTLRDIFKQEEPTGVIHFAGLKAVGESTRIPLAYYDNN
                     IAGTVSLLKAMEENNCKNIIFSSSATVYGDPHTVPILEDFPLSVTNPYGRTKLMLEEI
                     LTDIYKADSEWNVVLLRYFNPIGAHESGDLGENPNGIPNNLLPYVTQVAVGKLEQVQV
                     FGDDYDTEDGTGVRDYIHVVDLAKGHVAALKKIQKGSGLNVYNLGTGKGYSVLEIIQN
                     MEKAVGRPIPYRIVERRPGDIAACYSDPAKAKAELGWEAELDITQMCEDAWRWQSKHP
                     NGFED"
     gene            5887..6840
                     /locus_tag="VQ865_001769"
     CDS             5887..6840
                     /locus_tag="VQ865_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HET3136075.1"
                     /translation="MMISIIVPCLNEEEVLPLFYQALEALLPDLETEIEYVFVDDGSS
                     DGTLELLKAYREQNPAVHYISFSRNFGKEAALYAGLQYATGDLVVVMDADLQDPPSML
                     FEMKNVLDKNVDLDCVGTRRTSREGEPFFRSFCAVLFYRLMQKISPVALPSGVRDFRM
                     MRRSVVDAILSLTESNRFSKGLFAWVGFKTHYLDYPNVERQAGKTSWSFRQLFFYSIE
                     GIVNFSDFPLTIAFVAGLLSCFLSLLMTFFVVVRTLILGNPTSGWTSLMAVILFLGGI
                     QLLTIGILGKYISKIYLETKKRPLYLIKEKSDLPDFTEKIK"
     gene            complement(6902..7108)
                     /locus_tag="VQ865_001770"
     CDS             complement(6902..7108)
                     /locus_tag="VQ865_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HET3136076.1"
                     /translation="MKITLIPERCIACGLCQTYSDLFDYHDNGIVRFYDDPDQLEKEI
                     SPSQDVLEAVKNCPTRALIGNQEA"
     gene            7160..7636
                     /locus_tag="VQ865_001771"
     CDS             7160..7636
                     /locus_tag="VQ865_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM domain-containing protein"
                     /protein_id="HET3136077.1"
                     /translation="MAKEPWQEDIYDQEESRAGRRHRNHGGADRMANRILTILASIFF
                     VIVVVMVIVLIYLSSGGSNRTAALKDFHDSDASVVQISSSSSSQPEQSSEPESTSSSS
                     EEAANPEGTIKVLAGEGEAAIAARAGISIAQLEALNPGHMATGSWFANPGDVIKIK"
     gene            7645..8316
                     /locus_tag="VQ865_001772"
     CDS             7645..8316
                     /locus_tag="VQ865_001772"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000849376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HET3136078.1"
                     /translation="MKTIQIAIDGPASSGKSTVAKIIAKDFGFTYLDTGAMYRAATYM
                     ALKNQLGVEEVEALLALLDQHPISFGRSETGDQLVFVGDVDITHPIRENEVTNHVSAI
                     AAIPEVREKLVSLQQEIAQQGGIVMDGRDIGTVVLPQAELKIFLVASVDERAERRYKE
                     NIAKGIETDLETLKKEIAARDYKDSHRETSPLKQAEDAVYLDTTGLNIQEVVEKIKAE
                     AEKRM"
     gene            8447..8785
                     /locus_tag="VQ865_001773"
     CDS             8447..8785
                     /locus_tag="VQ865_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002920966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HET3136079.1"
                     /translation="MNNLPNCPKCNSEYVYEDGALLVCPECAHEWNPAEVAEVEEGLV
                     AIDANGNKLTDGDTVTLIKDLKVKGAPKDLKQGTRVKNIRIVEGDHNIDCKIDGFGAM
                     KLKSEFVRKI"
     gene            8788..9417
                     /locus_tag="VQ865_001774"
     CDS             8788..9417
                     /locus_tag="VQ865_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Pr6Pr family membrane protein"
                     /protein_id="HET3136080.1"
                     /translation="MSKHYKLVFYSRIFLFLAAFTGVYLEITRHGGFGMLLYYTVLSN
                     LLVTIFTLYLLKVMSRVGENWQRPSLLRLKGGVTMSIMITCVIYHFLLAPIATNFYTL
                     ENFLCHYIVPIWFLADTLFFDKQGQYKIWDPAVWTILPFLYMMFALFNGLVLKLNIPN
                     AKDNPFPYFFLNVNKGWNVVFKWCLIIFVAYMVAGFIFYFIKQIKRKSS"
     gene            9657..10808
                     /locus_tag="VQ865_001775"
     CDS             9657..10808
                     /locus_tag="VQ865_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3136081.1"
                     /translation="MKQFLERASILALSLVLITSFSISSALPAMFDYYQGYSKEQIEL
                     LVSLPSFGIMMMLLLNGFLEKIFPERLQISLGLLILSLSGTAPFWYQAYPFVFGTRLL
                     FGLGLGMINAKAISIISERYQGKRRIQMLGLRASAEVVGASLITLAVGQLLAFGWTAI
                     FLAYSAGFLVLPLYLLFVPYGKSKKEVKKRAKEASRLTREMKGLIFTLAIEAAVVVCT
                     NTAITIRIPSLMVERGLGDAQLSSFVLSIMQLIGIVAGVSFSFLISIFKEKLLLWSGI
                     TFGLGQIVIALSSSLWVVVAGSVLAGFAYSVVLTTVFQLVSERIPAKLLNQATSFAVL
                     GCSFGAFTTPFVLGAIGLLTHNGMLVFSILGGWLIVISIFVMYLLQKRA"
     gene            11126..11875
                     /gene="truA"
                     /locus_tag="VQ865_001776"
     CDS             11126..11875
                     /gene="truA"
                     /locus_tag="VQ865_001776"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HET3136082.1"
                     /translation="MTRYKATISYDGYAFAGFQRQSHARSVQEEIEKTLTRLNKGQAI
                     TVHGAGRTDSGVHALGQVIHFDLPYQIDEEKLRFALDTQSPEDIDVISIELVADDFHC
                     RYAKHSKTYEFIVDRGRPKNPMRRHYATHFPYPLDVERMQIAIKKLEGTHDFTGFTAS
                     GTSVEDKVRTITEASLIVDETGQFLTFTFSGNGFLYKQIRNMVGTLLKIGNNRMPVEQ
                     IALILEKKDRQLAGPTAAPNGLYLKEIRYEE"
     gene            11865..12638
                     /locus_tag="VQ865_001777"
     CDS             11865..12638
                     /locus_tag="VQ865_001777"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HET3136083.1"
                     /translation="MKNNRILALSGNDIFSGGGLSADLATYTLNGLHGFVAVTCLTAL
                     TEKGFEVFPTDDTIFQHELDSLRDVEFGGIKIGLLPTVSVAEKALDFIKQRPGVPVVL
                     DPVLVCKETHDVAVSELCQELIRFFPYVSVITPNLPEAELLSGQEIKTLEDMKTAAQK
                     LHDLGAPAVIIKGGNRLSQDKAVDVFYDGQTFTILENPVIQGQNAGAGCTFASSIASH
                     LVKGDKLLPAVESSKVFVYRAIAQADQYGVRQYEANKNN"
     gene            12616..13077
                     /locus_tag="VQ865_001778"
     CDS             12616..13077
                     /locus_tag="VQ865_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3136084.1"
                     /translation="MKQTKTTKIALVSLLTALSVVLGYFLKIPTPTGILTLLDAGVFF
                     AAFYFGSREGAVVGGLASFLLDLLSGYPQWMFFSLVNHGLQGFFAGFKGKSQWLGLIL
                     ATIAMVGGYALGSTLMNGWAAALPEILPNFMQNMAGMIVGFILSQSIKKIK"
BASE COUNT         3762 a         2466 c         2904 g         4027 t
ORIGIN      
        1 acccaactta gaacaagtac aaacaatgtt ggaacagaca ttcacagaga agcactacga
       61 gaatacgatt ctccatagtg accaaggctg gcaataccaa cacgattctt atcatcagtt
      121 cctagagagt aagggaattc aagcatccat gtcacgtaag ggcaacagcc cagacaacgg
      181 tatgatggag tccttctttg ggattctgaa atcggaaatg ttttacggtt atgagaagtc
      241 gtttcagtcg cgtaagcaat tggaacaagc tattgtagac tatattgatt actacaacaa
      301 taaacgaatt aaggtaaaac taaaaggact tagccttgtg caatacagaa ctaaatcctt
      361 cggataaatt aattgtctaa ctttttgggg ggcagtacat ttttggtata tataaaattt
      421 gtaggagcta tatctacaat tttatattcc cagtttatgg atgtcgctta ctatgttcac
      481 aatgttatcc agtgtttttt ctctaatatt taaggagtgt tctgtttctc gaataaattc
      541 ttcaaagttt aacccgtcaa cttgttcctg aacaagaaaa taatcatcca cgatataaaa
      601 ttcatcagtt aaattagtag tataactttt atcggctaat ttttttagca tgtaagcctc
      661 attttttata tcatcaagtg ctgtccattc tccttcggca tcataattca caaaaggtct
      721 tgactgcttg atgattactt tttgcccgtc cgattttcta attgcccgat aaacattccc
      781 tttatttgat ctcttaataa ttttttctat tttgtattta tttattgcag agtccttact
      841 tgaaacttca catgtggttt gaaaataaat ccttttttct tcttctgaaa ataaatccat
      901 tttccagcta ggaagactag ggaaattttg tctcttatct tctacatagt tcttcctttt
      961 ttcatctagc aataaataga tgactttttt atttttttca tcataagctt gtttttttaa
     1021 aaaagcccca tatctataat gaactggaga atgcattcca cattgatagt cagatagtat
     1081 ttttggagcc ttaaattctg acagtctatt cgtaagatta caaatcatac tcttagcttc
     1141 agattctgac ttaggatata gagttataaa tttgttagca gtagggctca tttccctagg
     1201 ggaattaatt ctttttaatt cctctaaatt tttaacaact ttaaagctac aattatttag
     1261 ttgggatagt ttatacacaa tcttaaaaat atttacagcg tcttttattt gggagcttat
     1321 gtgtattttc cacccttgtg caggcacctt atctgataaa taatagtaat tccaaatatc
     1381 accctgttgg aaatttttat cacattttaa acattctttc tctaataaat ccataacaaa
     1441 ctcctaatta ttaaaatagg ctagagacac agcactagcc tattccgtaa gtaaagctac
     1501 ttattttata taaaatataa ctagcgacct gtaattaaac aagtaaaaga acaatactta
     1561 gggagacctg tgacaatgat atcttcctct ggaagtagtt ctaattcaaa caatgtttgt
     1621 tccatgactg tatcctcctg ttatgataaa ttccagaaag catagagcaa attcgtggtt
     1681 cgtctgacta aatttcttat ctgaacacca ccttcaaata caaattttag tcaaactttt
     1741 attttttcta actttctaat tatattctac catgtgtttt tatatgtcaa gaattttctg
     1801 aataaactgt ttatttttta tttttttgac atttttgcaa attgtttaaa atctttcaat
     1861 tggattcact tattacttta ggacattgaa gcttctttcg ccagaggtgc ttatattact
     1921 gggaagttga agattgaaat gtggtataat aagaggtaat agagttttgg aaagagagag
     1981 aagatgattt caaagagatt agagttggta gcttcctttg tgccgcaggg agccatttta
     2041 ctagatgtgg ggagtgacca tgcttatttg cctatagagt tagtcgaaag aggaaaaatc
     2101 gaaagtgcca ttgcaggtga agttgtggag ggaccttatc agtctgctgt caaaaatgtt
     2161 gaggcccacg gcttggaaga aaaaatccaa gtccgtttag ccaatggttt ggcagctttt
     2221 gaagaggaag accgagtgtc tgtcattacc atcgcaggga tgggcggccg tttgattgct
     2281 aggattttag aagaaggctt ggacaagtta gctaacgtag agcgtttgat tctccagccc
     2341 aataatcgtg aagacgactt gcgtatctgg ctacaggatc atggattcca gattgtagca
     2401 gaaagcatct tagaagaagc tggaaagttt tatgagattt tggtggtgga agcaggacaa
     2461 atgaagctat cagccagtga tgttcgcttt ggtcccttct tgtccaaaga agtcagtcca
     2521 gtatttgtcc aaaaatggca aaaagaagct gagaagctag agttcgccct cggacaaatc
     2581 ccagaaaaaa atctggaaga acgtcaagtt ctagtagata agattcaagc tatcaaggag
     2641 gtgctccatg ttagcaagtg aagtgatcca agcttatgaa gccttttgcc ctcaggaatt
     2701 ttctatggag ggagacagcc gtggtctgca aattggcact ttagacaagg gtatccaaag
     2761 ggtcatggtt gccctcgata ttcgtgaaga gacagtggca gaggccattg aaaagggtgt
     2821 ggacttgatt atcgtcaagc acgcgcctat ctttcgtcct atcaaggact tgcttgccag
     2881 ccgtccgcaa aatcagattt acatcgacct gattaagcat gacatcgcag tttatgtcag
     2941 ccataccaat attgatatcg ttgaaaatgg gctcaatgac tggttttgtc agatgctagg
     3001 aatcgaggag acgacttatc tgcaggaaac aggtccagaa cgtggaattg gacgtattgg
     3061 gaatattcag cctcagacat tttgggaatt ggcccaacag gtcaagcaag tctttgacct
     3121 agatagcctt cgaatggtgc attatcaaga gaatgatttg cagaagccta tttcaagagt
     3181 agcaatttgt ggtggaagcg ggcagtcttt ctataaggat gctttggcaa agggggcaga
     3241 tgtctatatc actggtgata tctactacca tactgctcag gatatgctgt ctgatggctt
     3301 gttagcattg gatccaggtc actatatcga agtgcttttt gtggaaaaaa tcgcagcact
     3361 ccttactcaa tggaaagaga aaaaaggctg ggaactagag attttaccta gtcaagcatc
     3421 gaccaatcct ttccgtcata tctagttaga aagtgaagac aatgaaaaaa gttgccatta
     3481 ttggagcagg aattgtggga gcaacagctg cctactacct ctcgagagaa agtgacctag
     3541 aggtgaccgt ttttgaccat gagcaaggtc aagccaccaa ggccgcagca ggaattatca
     3601 gtccttggtt ttccaaacgc cgtaataaag cctggtacaa gatggcgcgc ttgggggctg
     3661 acttttatgt ggatttatta gctgatttag agaaatcagg acaaaaaatc gacttttacc
     3721 agcgttcggg agtctttctc ttgaaaaagg atgaatccaa gttggaagaa ctttatcaac
     3781 tggccctcca gcgcagagaa gaatctccct tgatagggca attagccatt ctggaccaag
     3841 cttcagctaa tgaattattc cctggtttgc agggatttga ccgcctgctc tatgcttctg
     3901 gtggagcgag agtagatggc caactcttgg taactcgtct gctagaagcc agtcatgtca
     3961 agctggtcaa agaaaaagtg actctgacac tcttatcatc aggctaccag attggcgaag
     4021 aggtgtttga tcaggttatt ttggcaacgg gagcttggtt gggggacatg ttagagcctt
     4081 taggttatga agtggatgtc cgtcctcaaa aaggacaact acgagattat cagcttgccc
     4141 aagacatgga agattaccct gttgtcatgc cagaagggga gtgggatttg attccctttg
     4201 caggtgggaa attatccttg ggcgctaccc atgaaaatga catgggattt gatttgacgg
     4261 tagatgaacc cttgctccaa caaatggagg aggcggcctt gcctcattac ccagttttag
     4321 ctagagcgac ttcaagggct gagcgtgtgg gaatccgtgc ctataccagt gatttctctc
     4381 ccttctttgg gcaggtgcca gaattggcag gtgtctatgt agccagtgga ctaggttcat
     4441 caggcctcac aactggtcct atcattggtt accatctagc ccaactgatc caagacaagg
     4501 agttgacctt ggaccctcta aattacccaa ttgaaaacta tgtcaaacga gtaaaaagcg
     4561 aataatactc aatgaaaatc aaagaacaaa ctaggaaact agccgcgggt tactcaaagc
     4621 actgctttga ggttgtgtat agaactgacg aagtcagctc aaaacactgt tttgaggttg
     4681 tgtatagaac tgacgaagtc agtaaccata cccatggcaa ggcgacgttg acgtggtttg
     4741 aattggattt tcgaagagta taagcatttt actgaaattt tatcaggtag tttaggatgg
     4801 caaatgacat tccctgtcaa aaatggtaaa ataagaaaaa ataatctgag aatcgaggaa
     4861 aaaagatgca agaaaagatt ttggtaactg gtggtgccgg ttttattgga acccacactg
     4921 ttattgaatt gatccaagca ggccatcaag ttgttgtggt ggataatctt gtcaatagca
     4981 atcgtaagag tttagaagtt gttgaaagaa tcacaggagt tgagattcct ttctatgagg
     5041 cagatattcg tgacacagtt accctcagag atattttcaa gcaggaagaa ccgactggtg
     5101 tcattcactt tgctggtttg aaggctgttg gcgaatcaac acgtatccct cttgcctact
     5161 atgacaacaa tatcgctgga actgtcagcc ttttgaaagc catggaagaa aacaactgta
     5221 aaaacatcat cttcagttct tctgcgacag tttacgggga tccgcacaca gtgcccatct
     5281 tggaagattt cccactttca gtgaccaacc catacggtcg taccaagctc atgctagagg
     5341 aaattttgac cgatatttac aaagcagact cagaatggaa tgttgtcttg cttcgttact
     5401 ttaacccaat cggagcccat gagagtggtg atttgggaga aaatccaaac ggtattccaa
     5461 acaatctctt gccatatgtg actcaagtag ccgttggaaa attagagcaa gtgcaagtgt
     5521 ttggagacga ttacgatacg gaagatggaa caggtgttcg tgactatatc cacgttgtcg
     5581 atttggctaa gggtcacgtt gcagctttga aaaaaatcca aaaaggttca ggactaaacg
     5641 tttataacct tggaactggt aaaggttact cagttcttga aattatccaa aacatggaaa
     5701 aagcggtggg acgtcctatt ccttaccgca tcgtagaacg tcgcccaggt gatatcgctg
     5761 cctgctactc agacccagca aaagctaaag cagaactcgg ttgggaagca gaactcgaca
     5821 tcacccaaat gtgtgaagac gcatggcgtt ggcaaagcaa gcatccaaat ggatttgaag
     5881 actaagatga tgatttcaat catcgtccct tgtttaaacg aagaggaagt acttcctctt
     5941 ttttatcagg ctctggaagc tttacttcca gatttggaaa cagaaatcga gtatgtcttt
     6001 gtcgatgatg gatcaagtga tgggaccttg gaactcttaa aggcctatcg ggagcaaaat
     6061 ccggcagtcc attatatttc tttctctcga aattttggca aagaagcagc cctttatgca
     6121 ggcttgcaat atgcgacagg agatttggtg gtggtgatgg atgcagacct ccaagatcct
     6181 cctagtatgt tgtttgagat gaaaaatgta ctagacaaaa atgtagactt ggactgcgtt
     6241 gggacacgga gaactagtcg ggagggagaa cccttctttc gcagtttctg tgctgttctc
     6301 ttttatcgcc tcatgcaaaa aatcagccca gtagctctgc cgtcgggtgt ccgtgatttt
     6361 cgtatgatga gaaggtctgt ggtcgatgcc attttaagct tgactgagtc caatcgtttt
     6421 tctaagggac tctttgcctg ggtcggcttt aaaacccact atctggacta tccaaatgtc
     6481 gaaaggcagg ctggcaagac cagttggagt tttaggcaac tcttttttta ctccattgaa
     6541 gggattgtta atttttcaga tttccctttg actatagcct ttgtagctgg tctcctatct
     6601 tgttttcttt ctctgctgat gacctttttt gttgtggttc ggaccctcat tttgggcaat
     6661 ccgacatctg gttggacctc tctgatggct gttattctct ttcttggagg cattcaactc
     6721 ttgaccattg ggattctcgg taagtatatc agtaagattt atttagagac taaaaaaaga
     6781 ccactttatc ttatcaaaga aaaaagtgac cttcctgatt ttacagaaaa aataaagtga
     6841 aaagactata attttacatg gaaatgtgct aaactagagg gagtggatta tcgccattga
     6901 tttaggcttc ctggtttcca atcagggcgc gagttgggca atttttaaca gcctctaaga
     6961 catcctgact aggagaaatt tctttttcca gttggtcagg gtcatcgtaa aaacgcacga
     7021 ttccattatc gtggtaatca aataaatcag aataagtttg gcaaagtcca caggcgatac
     7081 atcgttcagg tataagtgtg attttcatgt tcatatttat attgtaataa gaaaagtaaa
     7141 aaaaaacaag gagtaaggta tggcaaaaga accgtggcaa gaagatattt atgatcaaga
     7201 agaatcaaga gcagggcgtc ggcatcgaaa ccacggaggg gctgatagga tggctaatcg
     7261 tattttgacg atcctagcta gtattttctt tgtaattgtg gtggtgatgg tcatcgttct
     7321 catctatcta tcatcggggg ggagtaatcg cacagcagcc ttaaaagact ttcatgattc
     7381 tgatgcaagt gtagtacaaa tctcatcttc aagcagttct cagcctgagc agagttcaga
     7441 gccagaatct acttctagta gttcagaaga agctgctaat cctgaaggaa cgattaaagt
     7501 tctcgcagga gaaggggaag cagctattgc cgctcgtgca ggaatctcca ttgctcagtt
     7561 agaggccttg aatcctgggc acatggctac aggatcttgg tttgctaatc caggtgatgt
     7621 tataaaaata aaataggagc cgatatgaaa acaattcaaa ttgctattga tggtcctgct
     7681 tccagcggta agagtacggt cgcaaagatt attgctaagg attttggatt cacctacctt
     7741 gatacaggag ctatgtatcg tgcagcgacc tatatggctc ttaagaacca attaggagtt
     7801 gaagaagtcg aagcccttct agccttgttg gaccagcatc caatcagctt tggacgttca
     7861 gaaactggag accagcttgt ttttgtagga gatgtggata ttacccatcc tatccgtgaa
     7921 aatgaagtga ccaatcatgt ttctgctatt gcagcaattc ctgaagtgcg tgagaaactg
     7981 gtttctctcc aacaagaaat tgcccagcaa ggcgggattg tcatggatgg tcgcgatatt
     8041 ggaactgttg tattgccaca agcagaattg aaaattttcc tagtagcttc tgttgatgag
     8101 agagcagagc gtcgttacaa ggaaaatatt gccaagggaa ttgaaacaga ccttgaaacc
     8161 ctaaaaaagg aaattgctgc gcgtgactac aaggatagtc atcgtgagac ttctcctctc
     8221 aaacaagcag aggatgctgt ctaccttgat acaactggtt tgaacattca agaagtagtt
     8281 gaaaaaatca aagcagaagc tgaaaaaaga atgtaaatgt agaaaagccg atagattgat
     8341 atcggttttt ttctaaattt gtcaaaatgc tgattttagg gtataatagt tgctgttcga
     8401 gaaattttga ttttcaaaga atagtgaatg atgataagga gaaaccatga acaatttacc
     8461 aaattgtccc aaatgtaact cagagtatgt ctacgaagac ggtgccctac tggtttgccc
     8521 agagtgtgct catgagtgga atcctgctga agttgcagaa gtagaagaag gtcttgtcgc
     8581 tatcgatgcc aacggaaata aattgactga tggtgataca gtaactctca tcaaggactt
     8641 gaaagtaaaa ggtgcgccaa aagatttgaa acaagggacg cgcgtgaaaa atatccgcat
     8701 cgtagaaggc gaccacaata tcgactgtaa gattgatggt tttggtgcca tgaaacttaa
     8761 atcagagttt gtgaggaaga tttaagcatg tcaaaacact ataaacttgt attttatagc
     8821 cgtatcttct tgtttctagc ggcttttacg ggagtttatc ttgaaattac taggcatggt
     8881 ggttttggga tgcttctcta ttacacggtt ctgtccaacc tcttggtaac tatttttacc
     8941 ctttatcttc taaaggttat gagccgtgta ggtgaaaatt ggcaaaggcc aagtctcttg
     9001 cgcttaaaag gtggggtcac catgagcatc atgattacct gtgtgattta ccatttcctc
     9061 ttggcgccca ttgcgactaa tttctatacc ctagaaaatt tcctttgcca ctatatcgtt
     9121 cccatctggt ttttagcgga taccctcttt tttgacaaac agggtcaata caagatttgg
     9181 gatccagcag tgtggaccat tttacccttt ctgtatatga tgtttgctct ttttaatggc
     9241 ttggttctaa aactcaatat tccaaatgcc aaggataatc ctttccctta cttctttttg
     9301 aatgtgaaca agggttggaa tgttgtgttt aagtggtgtc tgattatctt tgttgcctat
     9361 atggtagcag gatttatttt ctactttatc aagcaaatca agagaaagtc atcctaatac
     9421 tcttcgaaaa tctcttcaaa ccacgtcagt ttccatctgc aacctcaaaa cactgttttg
     9481 aacaacctgc ggctagcttc ctagtttgct ctttgatttt cattgagtat aagatacaag
     9541 ggattcattt tcgaatttaa gaaggagtct acaaaccaat gaggcttctt cttttcttgc
     9601 ttatttgata actatcaaaa aagtagaaga ttaagagaaa tatagaaaga gatttcatga
     9661 aacaattttt agaacgggcc agcattttgg ctctctccct cgttttgatt acctcctttt
     9721 ccatttcgag tgccctacca gccatgtttg actattatca gggttattct aaggaacaaa
     9781 ttgagctctt ggtgagcttg ccttcctttg gaattatgat gatgttactg ctaaatggtt
     9841 tcttagaaaa aatatttcct gagcgcttac agattagttt gggcttgctg attttatcat
     9901 tgagcggtac agctcccttc tggtaccaag cctatccctt tgtctttgga acacggcttc
     9961 tctttggttt gggtcttggg atgatcaatg ccaaggccat ttctattatc agtgaacgct
    10021 accaaggaaa aaggcgaatt cagatgttag ggctacgcgc ttctgcagag gtcgttggag
    10081 cttctctcat taccttggcc gtcggtcagt tgttggcctt tggttggaca gctatctttc
    10141 tagcctatag tgctggattt ttggtgctgc ccctttatct gctctttgtc ccttatggaa
    10201 aatcaaagaa agaagtcaag aaaagagcga aggaagcaag tcgtttaact cgagaaatga
    10261 aaggcttgat ttttacctta gctatcgaag cggcagttgt agtttgtacc aatacagcta
    10321 ttaccatccg tattccaagt ttgatggtgg aaagaggatt gggggatgcc cagttatcta
    10381 gttttgttct tagtatcatg cagttgatcg ggattgtggc tggggtgagt ttttctttct
    10441 tgatttctat ctttaaagag aaactgctcc tctggtctgg tattaccttt ggcttggggc
    10501 aaattgtgat tgccttgtct tcatccttgt gggtggtagt agcaggaagt gttctggctg
    10561 gatttgccta tagtgtagtc ttgacgacgg tctttcaact tgtctctgaa cgaattccag
    10621 ctaaactcct caatcaagca acttcatttg ctgtattagg ctgtagtttc ggagccttta
    10681 cgaccccatt tgttctaggt gcaattggct tactaactca caatgggatg ttggtcttta
    10741 gtatcttagg aggttggttg attgtaatct ctatctttgt catgtaccta cttcagaaga
    10801 gagcttagga ttgattccta agtttttctt ttgatactca atgaaaatca aagagcaaac
    10861 tatagttgat tgagtttgga atagtacgct gtagctgcta aaatatttct agaaattaat
    10921 ttgactttcc taatagagtt attcatatct tatttcaatc tactatagaa agctagccgc
    10981 aggttgctca aaatagtgtt ttgaggttgc agatggaaac tgacgtggtt tgaagagatt
    11041 ttcgaagagt atgagatttt tatacccata caatatttgt tttaggtcct tgtttacaga
    11101 ctaatttctt gataaaatag aggttatgac gagatataaa gcaactattt cctatgatgg
    11161 ttatgccttt gctggctttc agcgccagtc tcatgcgcgt agcgttcagg aagaaattga
    11221 aaaaaccttg accagattaa ataaagggca agccattact gttcacggtg ctggtaggac
    11281 agatagtggg gttcatgccc tgggacaggt cattcatttt gacctgcctt atcagattga
    11341 tgaggagaaa ctccgttttg ccttggatac ccagtctcct gaagatattg atgtgatttc
    11401 gattgagctt gtggcagatg attttcattg ccgttatgcc aagcatagca agacctatga
    11461 gtttattgtg gatagaggac gtcccaaaaa tccgatgcgc cgtcactatg ccacccactt
    11521 tccctaccca ctcgatgtgg aacgaatgca gattgcaatc aaaaagctag agggaaccca
    11581 tgattttacc ggttttacag cctctgggac tagtgtagag gataaggttc gcaccatcac
    11641 agaagctagt ttaatagtcg atgagacagg acaatttttg acctttacct tttccggaaa
    11701 tggtttcttg tataaacaga ttcgcaatat ggtggggact cttctcaaaa tcggtaacaa
    11761 ccgcatgcca gtagagcaga ttgctctcat cttggagaag aaggacaggc aacttgcagg
    11821 tcccactgca gcaccaaatg gtttgtattt aaaggagatt cgttatgaag aataatcgta
    11881 ttttagcact ttctggaaat gatattttta gtggtggtgg actgtcagct gatttggcta
    11941 cctatacctt gaacggcttg catgggtttg tagcagtgac ttgtttgaca gccttgacag
    12001 aaaaaggatt tgaagtcttt ccaactgatg ataccatttt tcaacatgaa ttagatagct
    12061 tgcgtgatgt ggaatttggg ggaattaaga ttggtcttct ccctactgtc agtgtggctg
    12121 agaaggcctt ggactttatc aaacaacgcc caggagtacc tgtggtgttg gatcctgtct
    12181 tggtctgcaa ggaaacgcat gatgtagctg tcagtgagct ctgccaagag ttgattcgct
    12241 ttttccctta tgtcagtgtg attacgccta atctcccaga agcagaatta ttatccggtc
    12301 aggaaattaa aaccttggaa gacatgaaaa ctgcagcgca gaaattgcat gatttaggag
    12361 ctccagcagt cattatcaag ggaggcaatc gtcttagtca ggacaaggct gtggatgtct
    12421 tttatgatgg acagaccttt actatcctag aaaatccagt tatccaaggc caaaatgctg
    12481 gtgcaggttg tacctttgcc tctagcattg ccagtcactt ggttaaaggt gataaacttt
    12541 tgccagcagt agaaagttct aaggttttcg tttatcgtgc tattgcacaa gcagatcagt
    12601 atggagtaag acaatatgaa gcaaacaaaa acaactaaaa tcgcccttgt atccctatta
    12661 accgcccttt ctgtggttct aggttatttc ttaaaaatcc caacacctac aggaattcta
    12721 actcttttag atgctggtgt cttctttgcg gccttttact ttggtagtcg tgaaggagcg
    12781 gtagtcggag gactagcaag tttcttgctt gacctcttat caggctaccc tcagtggatg
    12841 ttttttagct tggtcaacca tggcttgcag ggatttttcg caggatttaa aggaaaaagt
    12901 cagtggttag gccttatttt agcaactatt gccatggtag ggggctacgc cttgggttct
    12961 actttgatga atggctgggc agcagccctc ccagaaattc taccaaattt tatgcaaaat
    13021 atggcaggga tgattgtagg atttattctt agtcaaagta tcaagaagat taagtaatac
    13081 tcttcgaaaa tctcttcaaa ccacgtcggc ttccatctgc aacctcaaaa cactgttttg
    13141 agcagcctgc ggctagctt
//
LOCUS       DAVBOG010000053        12973 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.053, whole genome shotgun sequence.
ACCESSION   DAVBOG010000053 DAVBOG010000000
VERSION     DAVBOG010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12973)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12973)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12973
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.053"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            87..3437
                     /locus_tag="VQ865_001779"
     CDS             87..3437
                     /locus_tag="VQ865_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000526318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3136085.1"
                     /translation="MGNFSFLLKNDEYESFSKPCIEAENMIATSTVATAFMARRALEQ
                     AVHWIYSHDSYLEAPYRATLSSLVWDDDFRDIVDSELHKQIVLLIRWGNHAAHGGEIK
                     EREAILALHHLYQFVNFIDYCYSNEFVERYFDEKCLPLSANIKYRETPQSMIKLQDSL
                     PELPDFHEQMAAQSVEVQETYTEKRETAAQRQDVPFHIDQLSEAETRKLFIDIDLRLA
                     GWIFEENCRVEIAVDGLKHGSGIGYCDYVLYGKNGKILAIVEAKKASVNPEVGEVQVK
                     EYAEALEKHIGYQPICFITNGLKHYILDGPNRRQIAGFYSQEELQLVMDRRHLQKPLE
                     DISSKIRDDISGRHYQKHAIASVCEAFSNHRRQALLVMATGAGKTRTAVSLVDILSRH
                     NWVKNVLFLADRTSLVKQAYDSFRKLLPDLSVCNFLEDKEGAQSSRMVFSTYPTMIGA
                     ISGQEEVNQRPFTVGHFDLIIIDESHRSIYQKYKSIFDYFDARIVGLTATPRQDLDKN
                     TYGFFNLENGVPTYAYDLEEAVKDGYLVAYHSIETKLKLPTDGLHYDDLSEEEKEHFD
                     SKFEDDSCEKDIDGSVFNSFVFNKSTVEIVLNELMTRGIQTASGDEIGKTIIFAKNHD
                     HAEYIRGIFNNRYPEKGSDYAQVIDYSIKHYQTLIDDFKIKEKYPQIAISVDMLDTGI
                     DVPEVVNLVFFKKVRSKTKFWQMIGRGTRLCKDLFGPEQDKENFLVFDYGDNFDYFRA
                     DPRDGEGRHIVSLTQRLFNIKVDLIRELQGLQYQEDQFARAYRQQLVSELQGRIESLN
                     ELDFRVRMVLDTVYSYRKLESWQNLTAVTSETIQKNLSPLLFDEDKEDEMARRFDLWL
                     LHIQLGQLTAKSSTVHISQVMKTARALSAIGNIPQVFEQAEIIRKVQEPEFWKEVNLS
                     DLEKIRLAIRDLLQFLDKTDRKPYYVNFEDRILSTVHETTAFLQVNDLRSYNEKVEHY
                     LKTHLDEESISKLYHNKKLTSDDMLALEKLLWEKLGSKADYQSHYENKAIPRLVREII
                     GLDRESANRIFSKFLSDENLNARQISFVKLIVDYIVENGFLETKVLTQEPFKSYGSVQ
                     LLFQHQLPVLRNIVQIIELINNRAGEAA"
     gene            3681..3782
                     /locus_tag="VQ865_001780"
                     /pseudo
     CDS             3681..3782
                     /locus_tag="VQ865_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopyranose mutase"
     gene            complement(4023..4493)
                     /locus_tag="VQ865_001781"
     CDS             complement(4023..4493)
                     /locus_tag="VQ865_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HET3136086.1"
                     /translation="MNKSEHRHQLIRALITKNKIHTQAELQALLAKNDIQVTQATLSR
                     DIKNMNLSKVREEDSAYYVLNNGSISKWEKRLELYMEDALVWMRPVQHQVLLKTLPGL
                     AQSFGSIIDTLSFPDAIATLCGNDVCLIICEDADTAQKCFEELKKFAPPFFFEE"
     gene            complement(4510..6783)
                     /locus_tag="VQ865_001782"
     CDS             complement(4510..6783)
                     /locus_tag="VQ865_001782"
                     /EC_number="3.4.14.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidyl-peptidase"
                     /protein_id="HET3136087.1"
                     /translation="MRFNQYSYINFPKENVLSELKKCGFDLQNTANHKDSLETFLRRF
                     FFTYQDTNYPLSILAADKKTDLLTFFQSEDELTADIFYTVAFQLLGFSYLVDFEDSDV
                     FRKETGFPIIYGDLIENLYQLLNTRTKKGNTLIDQLVSDGLIPEDNDYHYFNGKSLAT
                     FSNQDVIREVVYVESRVDTDQKGLSDLVKVSIIRPRFDGKIPAIMTASPYHQGTNDKA
                     SDKALYKMEGELEVKLPHKIELEKPQLNLVQPQGQAELIAEAEEKLTHINSSYTLNDY
                     FLPRGFANLYVSGVGTKDSTGFMTNGDYQQIEAYKNVIDWLNGRCRAFTDHTRQRQVK
                     ADWSNGKVATTGLSYLGTMSNGLATTGVDGLEVIIAEAGISSWYNYYRENGLVTSPGG
                     YPGEDFDSLAELTYSRNLLAGDYIRGNEAHQADLEKVKAQLDRKTGDYNQFWHDRNYL
                     LNAHKVKAEVVFTHGSQDWNVKPLHVYQMFHALPTHIHKHLFFHNGAHVYMNNWQSID
                     FRESINALLTKKLLGQETDFQLPTVIWQDNTAPQTWLSLDNFGGQENCKTFSLGQEEQ
                     AIQNQYPDKDFERYSKTYQTFNTELYQGKANQITINLPVTKDLHLNGRAQLNLRIKSS
                     TNKGLLSAQLLEFGQKKYLQPYPAILSARTIDNGRYHMLENLCELPFRPEAQRVVTKG
                     YLNLQNRNDLLLVEDITADEWMDVQFELQPTIYKLKEGDTLRLVLYTTDFEITIRDNT
                     DYHLTVDLAQSMLTLPC"
     gene            7129..10230
                     /locus_tag="VQ865_001783"
     CDS             7129..10230
                     /locus_tag="VQ865_001783"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000561528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HET3136088.1"
                     /translation="MIAQLDTKTVYSFMESVISIEKYVRAAKEYGYTHLAMMDIDNLY
                     GAFDFLEITKKYGIHPLLGLEMTVFVDEQEVNLRFLSLSSVGYQQLMKLSTAKMQGEK
                     TWSVLSQYLEDIAVIVPYFDRVESLELGCDYYIGVYPETLASEFHHPILPLYRVNAFE
                     SRDREVLQVLTAIKENLPLREVPLRSRQDVFISASSLEKLFQECFPQALDNLEKLISG
                     ISYDLDTSLKLPRFNPARPAVEELRERAELGLVQKGLTSKEYQDRLDQELSVIHDMGF
                     DDYFLVVWDLLRFGRSNGYYMGMGRGSAVGSLVSYALDITGIDPVEKNLIFERFLNRE
                     RYTMPDIDIDIPDIYRPDFIRYVGNKYGSKHAAQIVTFSTFGAKQALRDVLKRFGVPE
                     YKLSAITKKISFRDNLKSAYEGNLQFRQQINSKLEYQKAFEIACKIEGYPRQTSVHAA
                     GVVISDQDLTNYIPLKYGDEIPLTQYDAHGVEASGLLKMDFLGLRNLTFVQKMQELLA
                     ETEGIHLKIEEIDLEDKETLDLFASGNTKGIFQFEQPGAIRLLKRVQPVCFEDVVATT
                     SLNRPGASDYINNFVARKHGQEEVTVLDSALEDILAPTYGIMLYQEQVMQVAQRFAGF
                     SLGKADILRRAMGKKDASAMHEMRASFIQGSIEAGHTAEKAEQVFDVMEKFAGYGFNR
                     SHAYAYSALAFQLAYFKTHYPAIFYQVMLNYSNSDYLIDALEAGFEVASLSINTIPYH
                     DKIANKSIYIGLKSIKGLSKDLALWIIEHRPYSNIEDFIAKLPENYLKLPLLEPLVKV
                     GLFDSFEKNRQKVFNNLANLFEFVKELGSLFGDAIYSWQESEDWTEQEKFYMEQELLG
                     IGVSKHPLQAIASKAIYPITPIGNLSENSYAIILVEVQKIKVIRTKKGENMAFLQADD
                     SKKKLDVTLFSDLYRQVGQEIKEGAFYYVKGKIQSRDGRLQMIAQEIREAVAERFWIQ
                     VKNHESDQEISRILEQFKGPIPVIIRYEEEQKTIVSPHHFVAKSNELEEKLNEIVMKT
                     IYR"
     gene            10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ865_001784"
     CDS             10313..11320
                     /gene="pfkA"
                     /locus_tag="VQ865_001784"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HET3136089.1"
                     /translation="MKRIAVLTSGGDAPGMNAAIRAVVRQAISEGMEVFGIYDGYAGM
                     VAGEIHPLDAASVGDIISRGGTFLHSARYPEFAQLEGQLKGIEQLKKHGIEGVVVIGG
                     DGSYHGAMRLTEHGFPAIGLPGTIDNDIVGTDFTIGFDTAVTTAMDAIDKIRDTSSSH
                     RRTFVIEVMGRNAGDIALWAGIATGADEIIIPEAGFKMEDIVASIKAGYECGKKHNII
                     VLAEGVMSAAEFGQKLKEAGDTSDLRVTELGHIQRGGSPTARDRVLASRMGAHAVKLL
                     KEGIGGVAVGIRNEKMVENPILGTAEEGALFSLTAEGKIVVNNPHKADIELSSLNKSL
                     S"
     gene            11379..12884
                     /gene="pyk"
                     /locus_tag="VQ865_001785"
     CDS             11379..12884
                     /gene="pyk"
                     /locus_tag="VQ865_001785"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HET3136090.1"
                     /translation="MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAK
                     LIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAGKKVGFLLDTKGPEIRTELFEGE
                     AKEYSYKTGEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
                     VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIA
                     ISFVRTAKDVNEVRAICEETGNGHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMG
                     IEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATRSEVSDVFNAVIDGT
                     DATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVK
                     DATNSMDIKLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTD
                     APSSTDDMFEIAERKAVEAGLVESGDDIVIVAGVPVGEAVRTNTMRIRTVR"
BASE COUNT         4022 a         2204 c         2850 g         3897 t
ORIGIN      
        1 gcttgtgaga tagctataaa agtgtggaga aatagcttga aatttagtat aatatagcta
       61 aactatttgt ttaaagtgag aaaaaaatgg gaaattttag ctttctttta aaaaatgacg
      121 aatatgaatc tttttcaaaa ccttgcattg aagctgagaa tatgattgct acatcaactg
      181 tggctactgc ctttatggcg cgtcgtgctt tagagcaggc tgtccattgg atatatagtc
      241 acgattcata tttagaagct ccctatcgtg ctactctatc ttctttagta tgggatgatg
      301 attttaggga tatcgtagat tctgaactcc acaagcagat agttctgttg attcggtggg
      361 gaaaccatgc tgctcatggt ggtgaaatta aggaacgaga agcgatttta gctttgcatc
      421 atttgtatca gtttgttaat tttatcgatt attgttacag caatgagttt gtggagcgtt
      481 attttgatga gaagtgctta ccactttcag caaacatcaa ataccgagaa actccacaat
      541 ctatgataaa gttacaagac agtttaccag aactgcctga ttttcatgaa cagatggctg
      601 ctcagtccgt agaagttcaa gagacttata ctgaaaaacg tgagactgca gcgcaacggc
      661 aagatgtgcc tttccatatt gatcaattat ctgaggcaga gacaagaaag ctctttattg
      721 atatcgatct ccgtttagca ggatggatat ttgaagaaaa ctgtcgtgtt gagatagccg
      781 ttgatggtct caagcacggt tcaggaattg gttactgtga ctatgtactt tatggtaaaa
      841 atgggaaaat tttagcgatt gtagaggcta aaaaagcctc tgtcaatcca gaagtagggg
      901 aagtacaggt caaagaatat gctgaagctc ttgagaaaca tatcggctat cagccaattt
      961 gctttattac aaatggcttg aagcactata tacttgatgg tccgaaccgc cgccagattg
     1021 caggctttta ctctcaagaa gaattgcaat tagtgatgga tagacgtcat cttcaaaaac
     1081 cacttgagga tatttctagt aaaattaggg acgatatttc cgggcgtcac taccaaaaac
     1141 atgccattgc aagcgtttgt gaagctttct ctaatcatcg tagacaggca cttttggtta
     1201 tggcaactgg ggctgggaaa actcgtacag cagtttctct agttgatatc ttatcacgtc
     1261 ataactgggt aaaaaacgtt ctcttcttag ccgatagaac ttccttggtt aagcaagcct
     1321 atgattcgtt tagaaaatta ctcccagatc tttccgtttg taacttctta gaagataaag
     1381 aaggagctca atcaagtcgc atggtctttt caacttatcc gaccatgatt ggagcgatta
     1441 gtggtcaaga agaagtaaat caacgccctt tcactgttgg gcattttgac cttatcataa
     1501 ttgacgaatc tcaccgttct atttatcaga aatacaagtc catttttgat tattttgatg
     1561 caagaattgt aggcttaaca gctactccgc gtcaagattt agataaaaac acctatggat
     1621 tctttaattt ggagaatggg gttccaacat atgcatatga tttggaagag gctgttaaag
     1681 acggatattt agtagcctat cattctatcg aaaccaaact gaaactacct acggatggtc
     1741 tacattatga tgatttgtcc gaagaagaaa aggaacattt tgatagcaaa tttgaagacg
     1801 atagctgtga aaaagatatt gatgggagtg tatttaattc ctttgttttc aataaaagta
     1861 cagtagaaat tgttttaaat gaactcatga caagaggaat tcagacagcc tcgggtgatg
     1921 aaattggtaa aactattatt tttgctaaaa atcatgatca tgcggaatat atcagaggta
     1981 tttttaacaa ccgctatcct gaaaaaggga gcgactatgc tcaggtgatt gattatagta
     2041 ttaagcatta tcagaccttg attgatgatt ttaaaattaa ggagaagtat cctcaaattg
     2101 cgatttctgt cgatatgtta gatacaggta ttgatgtacc agaggttgtt aatttagtct
     2161 tcttcaagaa agtacgctct aaaactaagt tttggcagat gattggtcga ggaacccgtc
     2221 tatgtaaaga tttatttgga cctgagcagg ataaggaaaa cttcttggta tttgattatg
     2281 gggacaattt tgattatttt cgtgcagatc caagagatgg agagggtcgt cacattgttt
     2341 cgttgactca gcgtttattt aatatcaaag tggacttgat tcgagaactt cagggactcc
     2401 aataccaaga agatcagttt gcgagagcat accgtcagca gcttgtctcg gaacttcaag
     2461 gtcgtataga gagcttaaat gagttggact tcagggttcg tatggtttta gatacagttt
     2521 atagctatag gaaattggaa agttggcaga atctaactgc tgttacaagt gaaaccattc
     2581 aaaaaaatct ctctccgctt ttatttgatg aagataaaga agatgagatg gcgaggagat
     2641 ttgatttgtg gttgcttcat attcagttgg ggcaactgac agctaaatct tccactgttc
     2701 atatttccca agtgatgaag acggctagag ctctttctgc tattggcaat atcccgcagg
     2761 tttttgagca ggctgaaatt atcaggaaag tacaggagcc tgaattttgg aaagaagtta
     2821 acttgtctga tttggaaaaa attcgtcttg ctattcgaga tttattacag tttttggata
     2881 aaacagaccg taaaccctac tatgttaact ttgaagatcg tatactctcc actgttcacg
     2941 agaccacagc atttttgcag gtcaacgatc ttcggtctta caatgaaaaa gttgagcatt
     3001 atttgaaaac tcatctggat gaggagtcca tttctaagct ataccataat aaaaagttga
     3061 catctgatga tatgcttgca cttgaaaaat tgctctggga aaaattaggt agtaaagcag
     3121 actaccaaag tcattatgaa aataaggcaa ttccgagatt ggttcgtgag attattggct
     3181 tagatagaga gtctgccaat cgtatttttt ctaaattttt gtcggatgag aatcttaatg
     3241 ccaggcagat ttcatttgta aaattgattg tagactacat tgtagaaaat ggttttttag
     3301 agacgaaagt gttaacgcaa gagccgttta aatcttatgg ttctgttcaa ctactcttcc
     3361 aacaccaact accagtactt cgtaatattg ttcaaatcat tgaacttatc aataatcgag
     3421 ctggagaagc ggcttaaatt ctaaagtgat tgccatgctg agactcattt aaaattaaaa
     3481 agagtagaaa tttatgctat atatgagaag ttttattagg aagaatgtca tcgttttcct
     3541 agaatacagt atcagttgtt aagtggctga taaatttcaa agtagatact tgtaccacga
     3601 tgtttgttga tcgagttatt aacaaaagag ctactttgat tttaaagaaa tagaaaacaa
     3661 aaagccgagc aagaattcaa ttgcaggaga aaatgaaata atactcaatg aaaatcaaag
     3721 agcaaactag gaaattagct gcaggctgct caaaacactg ttttgaggtt gtagataaga
     3781 ctgacgaagt cagctcaaaa catggttttg aggttgtaga tgaaactgac gaagtcagta
     3841 accataccta cggcaaggcg acgttgacgc ggattgaaga gattttcgaa gagtataaat
     3901 cttcctagga taaagcaaaa cgcatagtat caagtgttga aaacccttga tactatgcgt
     3961 tttctgatgt taaagacttt ctaccagttt ttttaagcat aattgttagt tgtagtcatt
     4021 tattattctt caaagaaaaa tggtggggcg aattttttca gttcttcaaa gcacttttga
     4081 gcagtatctg catcttcaca gatgataaga cagacatcat taccacaaag ggtagcgata
     4141 gcgtcaggga agctcaaagt atcaatgata gaaccaaagg attgagccag tccaggaagg
     4201 gtttttagta ggacttggtg ttgaactggg cgcatccaga caagggcgtc ttccatgtag
     4261 agttcgagac gtttttccca ttttgagatg gaaccattgt taagaacata ataagcgcta
     4321 tcttcttcgc ggacttttga taggttcata tttttgatgt cgcgtgagag ggttgcctgg
     4381 gttacttgaa tgtcgttctt agcaagaagg gcttgcaact cagcctgtgt atgaatcttg
     4441 ttttttgtga taagagcgcg tataagttgg tggcggtgtt ctgatttatt cataataatg
     4501 taactccttt tagcaaggta aggtaagcat ggactgagcg aggtcgacag tcaagtggta
     4561 gtctgtattg tcacggatgg tgatttcaaa gtcagtagta tagaggacta aacggagagt
     4621 gtctccttct tttagcttgt aaatagttgg ctgcagttca aattgaacgt ccatccattc
     4681 atctgcagta atatcctcta ctaacagtaa atcatttcta ttttgtaaat taaggtaacc
     4741 ttttgtcacg actcgttgtg cctctggtct aaatggcaat tcacagagat tttccaacat
     4801 gtgatagcga ccgttatcaa tggttctagc acttaaaata gctggataag gttgtaggta
     4861 tttcttttgc ccaaattcta gcagttgggc agataagagc cccttgtttg tactggattt
     4921 gatacgaaga ttgagctgag cgcgaccgtt taggtggaga tctttagtca caggaaggtt
     4981 aatagtaatc tgattagctt tcccttgata gagctctgta ttgaaggttt ggtatgtctt
     5041 actatagcgc tcaaaatcct tatctgggta ctggttttga atagcttgct cttcttgacc
     5101 aagtgagaag gttttacagt tttcttgccc accgaagtta tcaagtgata accaagtctg
     5161 tggagctgta ttgtcctgcc agataacagt aggaagttga aagtctgttt cctgtcctag
     5221 taatttcttg gttaataagg catttatgga ctcacggaag tcaattgatt gccaattgtt
     5281 catgtaaaca tgggcaccat tatggaaaaa gagatgcttg tgtatatgag taggaagagc
     5341 atggaacatc tggtaaacat gaagtggttt gacattccaa tcctgagaac catgagtaaa
     5401 gacaacctct gcctttactt tatgggcatt gagcagataa ttgcggtcat gccaaaactg
     5461 attgtagtcc ccagtttttc ggtctagctg agctttcact ttttctaagt cagcttggtg
     5521 agcttcattg ccacggatat agtcgccagc taagagatta cgagaatagg ttaactcagc
     5581 aagggagtca aagtcctcac ctggataacc acctgggcta gtcaccagac cgttttcacg
     5641 gtagtagttg taccatgatg aaattcctgc ctcggcaatg ataacttcta aaccatcgac
     5701 tcctgtagtc gcaagaccat tggacatggt acctagatag gaaagtcccg ttgtagcaac
     5761 ttttccgttt gaccaatcag ccttgacttg acgctggcgc gtgtgatcag taaaggcacg
     5821 gcaacggccg ttaagccaat cgatgacatt tttataagcc tcgatttgct ggtagtctcc
     5881 attagtcatg aaacctgtcg agtctttggt accaacacct gagacataga gattggcaaa
     5941 gcctctcgga aggaagtagt cgtttagtgt atagctagag ttgatgtgag ttagcttttc
     6001 ctcagcctct gctataagct cagcttgacc ttggggttgg acgagattta gttgaggttt
     6061 ctctagctca atcttgtgag gaagcttaac ctcaagctcg ccctccatct tgtagagagc
     6121 cttgtcacta gccttgtcat tggttccctg atgataaggg ctggctgtca tgatggcagg
     6181 gatttttcca tcaaaacgag ggcgaataat gctaaccttt actaggtctg atagcccttt
     6241 ttggtcagta tcgacacgag actcaacgta aacgacttca cgaatgacat cctggttaga
     6301 aaaagtagcc aaactcttgc cgttaaagta gtggtagtca ttatcctccg gaataagacc
     6361 atcactaaca agttggtcga taagagtatt tccttttttg gtgcgagtat tgagtaactg
     6421 atagagattt tcaatcaagt caccatatat aatgggaaat ccagtttctt tacgaaaaac
     6481 gtcactatct tcgaagtcaa ccaaataaga aaagcctaaa agttgaaaag caacagtata
     6541 aaaaatatct gctgtcagtt catcttctga ttgaaaaaat gtcagcaggt ctgttttttt
     6601 atcagctgct aggatagaaa gtgggtagtt ggtgtcttga taagtgaaaa agaaacgacg
     6661 taaaaaggtt tcaagtgagt ctttgtgatt ggctgtattt tgtaaatcaa agccacattt
     6721 ttttagctca gataagacat tttcttttgg aaaattgata taactatatt gattaaaacg
     6781 catagaacct ccatatagaa tgacagttaa ggttattata tcaaaaaaaa agcagaaagg
     6841 gaattgttaa cttcaaaagg aaataatcca ataaaaatga ataaagtact aaattcaata
     6901 tagagaacag agtaacaata agaataatag atagggtata aaagttctag gagatttata
     6961 ttatatgctt tctattttta tatacaatat agtataaata taaaaatgat gacaaaaata
     7021 caaatgaata gaaaataaat tagtaagctg atgaaatttt tctcaagaga agccatttat
     7081 aggtgaaaat ggtataatat agtgagaagg atagaggaga agtgtaaatt gatcgcacaa
     7141 ctagatacaa aaacagtcta tagttttatg gaaagcgtca tttcgatcga aaagtatgtg
     7201 agagcagcta aagaatacgg ctacactcat ttggctatga tggatattga caatctttat
     7261 ggcgctttcg actttctaga gattacaaaa aaatacggca ttcatccttt gctagggctt
     7321 gaaatgacag tgtttgtaga tgaacaggaa gtgaatttgc gctttttatc tctatctagt
     7381 gtgggctatc agcagttgat gaagctttcg acagccaaga tgcaggggga gaaaacttgg
     7441 tcagtcctgt cccagtacct ggaggatatc gcggtcattg tgccttattt tgatagagtt
     7501 gagtcgttag aactaggctg tgattactat ataggggttt atccagaaac actagcaagc
     7561 gaatttcatc atcctatctt acctctttat cgggtcaacg cttttgaaag cagggataga
     7621 gaagttcttc aagttttaac agcgattaaa gaaaatctac cgctcagaga agttcccttg
     7681 cgttcgagac aagatgtctt tatatcagca agttctttag agaaactatt ccaagagtgt
     7741 tttccgcaag ctttggacaa tttagaaaag cttatttcag gcatttctta cgacttggat
     7801 actagtctga aactgcctcg ttttaatcca gctagaccag cagtagagga gttgagagag
     7861 cgtgctgaac tggggcttgt tcagaagggg ttgactagta aagaatatca agatagacta
     7921 gaccaagaat tgtctgttat tcatgatatg ggctttgatg attatttctt ggttgtttgg
     7981 gatttgttgc gttttggacg atcgaatggc tattatatgg gaatgggaag gggttctgca
     8041 gtaggcagtt tggtttctta tgccttagac atcacgggga ttgacccagt agagaaaaat
     8101 ctgatttttg aacgctttct taatcgtgaa cgctatacca tgcctgatat tgatattgat
     8161 atcccagata tttatcgtcc agattttatc agatatgttg gtaataaata tggtagtaaa
     8221 catgcggcac aaatcgttac tttttcaacc tttggagcca agcaagctct tcgagatgtc
     8281 ttgaaacgct ttggtgtgcc agagtataaa ttatctgcaa ttactaagaa aatcagtttt
     8341 cgtgacaatc ttaagtcggc ctatgagggc aatctccagt ttcgtcagca aatcaatagt
     8401 aagttagaat accaaaaagc ttttgagatt gcttgcaaga tagagggcta tccaaggcaa
     8461 acctctgtcc atgcggctgg tgttgtaatt agtgaccaag atttaaccaa ctacattcct
     8521 ctaaagtatg gtgatgaaat tccactgact cagtatgatg ctcatggagt tgaggctagc
     8581 ggacttttga agatggactt tctgggacta cgaaatttga cctttgtcca gaagatgcaa
     8641 gagttgcttg ctgaaacaga aggtattcac cttaaaattg aagaaataga tttggaagac
     8701 aaagaaacgt tagatttatt tgcctctgga aatacaaaag gtatctttca atttgagcaa
     8761 cctggtgcca ttcgcttgct caaacgtgtt caaccagtct gttttgaaga tgtcgtagca
     8821 actacttctc taaatcgacc aggtgcaagt gactacatca ataattttgt ggcaaggaag
     8881 catgggcagg aagaagtgac tgttctagat tcagctctgg aggatatttt ggctccaact
     8941 tatggcatta tgctctatca ggagcaggtt atgcaggttg ctcagcgatt tgctggattt
     9001 agtcttggga aggccgatat tttgcgtcga gctatgggta aaaaggatgc ctctgctatg
     9061 catgagatga gggcttcctt tattcaaggc tccatagaag caggccatac tgcggaaaaa
     9121 gcagagcagg tttttgatgt tatggagaag tttgcaggtt atggatttaa tagatctcat
     9181 gcctacgcct actcagcctt ggccttccag ttggcttatt tcaaaacgca ttatccagcc
     9241 attttttatc aggtcatgtt aaattattcc aacagtgatt acttaataga tgcacttgaa
     9301 gcaggttttg aagtagcctc tctatccatc aatactattc cctatcacga taaaattgcc
     9361 aacaagtcta tctatatagg tttgaaatcg attaaggggc tcagcaagga cttggcgctt
     9421 tggattattg aacatagacc ttattctaac attgaagatt ttatagctaa attacctgag
     9481 aattatctga aacttcctct gctagaacct ttggtaaaag ttggtctttt cgattcattt
     9541 gaaaaaaatc gtcaaaaagt atttaataac ttagctaatc tatttgaatt tgtgaaagag
     9601 ttgggaagtt tgtttggaga tgctatttat agttggcagg aatcggaaga ttggacggaa
     9661 caagaaaaat tttatatgga acaagagctt ttagggatag gtgtcagcaa acatccacta
     9721 caagctattg caagtaaggc tatttacccg attaccccaa tcggaaattt gtcagaaaat
     9781 agctatgcta ttattttggt tgaagttcag aaaataaaag tgattcgtac caaaaagggt
     9841 gaaaatatgg ccttcttaca ggcagatgat agtaagaaaa aattggatgt cactctcttt
     9901 tcagacttat atcgtcaggt tggacaggaa ataaaagagg gagccttcta ctatgtaaaa
     9961 ggaaaaatac aatcacgtga tggccgtttg caaatgattg cacaagaaat aagagaagca
    10021 gttgctgaac gcttttggat acaggtgaaa aatcatgaat cggatcaaga aatttcacgt
    10081 attttagaac aatttaaagg cccaatccca gtcatcatcc ggtatgaaga ggaacagaaa
    10141 accatcgttt ctccccatca ttttgtagct aaatccaatg aattagagga gaaattgaat
    10201 gaaatcgtta tgaaaacgat ttatcgctaa aaatacggaa aatagaagaa ttttaaaatc
    10261 aaatgtgata taatcaagaa gaatgttaaa agaaaaagga gcataaacca atatgaaacg
    10321 tattgctgtt ttgactagtg gcggagacgc acctggtatg aacgctgcta tccgtgcagt
    10381 tgttcgtcaa gcaatttcag aaggaatgga agtgtttggt atctatgacg gatatgctgg
    10441 tatggttgcc ggtgaaattc atcccctaga tgcagcttca gtaggagaca tcatttctcg
    10501 tggtggtact tttcttcact cagctcgtta cccagagttc gctcaacttg aagggcaact
    10561 taaagggatt gagcaattga aaaaacacgg aattgaaggt gtagttgtta tcggtggtga
    10621 cggatcttac cacggcgcta tgcgtttgac tgaacatggc ttcccagcta ttggtcttcc
    10681 aggtacaatc gataacgata tcgttggtac tgactttaca atcggttttg acacagcggt
    10741 tactactgcc atggacgcta tcgataagat tcgtgataca tcatcaagtc accgtcgtac
    10801 ttttgtaatc gaagttatgg gacgtaacgc tggtgatatc gctctttggg ctggtattgc
    10861 aactggtgct gatgaaatca tcatccctga agcaggcttc aagatggaag atatcgtagc
    10921 aagcatcaaa gctggttatg aatgtggtaa aaaacacaat atcatcgtct tagctgaagg
    10981 tgtgatgtca gcggctgaat ttggtcaaaa acttaaagaa gctggagata caagcgacct
    11041 tcgtgtaaca gaacttggac atattcaacg tggtggttct ccaactgcgc gtgaccgtgt
    11101 tttagcgtca cgtatgggtg cacatgctgt taaacttctt aaagaaggta tcggtggtgt
    11161 tgcggttggt attcgtaacg aaaaaatggt tgaaaatcca attcttggta ctgcagaaga
    11221 aggggcattg tttagcctta ctgcagaagg taagattgtg gttaacaacc cgcacaaagc
    11281 cgatattgag ctatctagct tgaataagag cttgtcataa tttacaattt agttaataag
    11341 accaaaaagg tcatatatat aaaggagtca caaaaatcat gaacaaacgt gtaaaaatcg
    11401 ttgcaacttt gggtcctgcg gtagaaatcc gtggtggtaa aaaattcggt gaggacggat
    11461 actggggtga aaaacttgat gttgaagctt cagctaaaaa cattgctaaa ttgattgaag
    11521 ctggtgctaa cacattccga ttcaacttct cacacggcga ccaccaagaa caaggtgagc
    11581 gtatggcaac tgttaaactt gcggaaaaaa ttgcaggtaa aaaagttggt ttccttcttg
    11641 atacaaaagg acctgaaatc cgtacagaat tgttcgaagg tgaagctaaa gaatattcat
    11701 acaaaactgg tgaaaaaatt cgtgttgcaa ctaaacaagg aatcaaatca actcgtgaag
    11761 tgattgcgtt gaacgttgct ggtgctcttg atatctatga tgatgttgaa gttggtcgtc
    11821 aagttttggt tgacgatggt aaacttggtc ttcgtgtggt tgctaaagat gatgcaactc
    11881 gtgaatttga agttgaagtt gaaaacgatg gtatcatcgc taaacaaaaa ggtgtgaaca
    11941 tccctaacac taaaattcct ttcccagctc ttgctgaacg cgataacgac gatatccgtt
    12001 tcggtcttga acaaggtatc aacttcatcg caatttcatt cgtacgtact gcaaaagatg
    12061 tgaacgaagt tcgtgcaatc tgtgaagaaa ctggaaacgg acatgttcaa ttgttcgcta
    12121 aaatcgaaaa ccaacaaggt atcgataact tagacgaaat catcgaagca gctgatggta
    12181 ttatgattgc tcgtggtgat atgggtatcg aagtaccgtt cgaaatggtt ccagtttatc
    12241 aaaaaatgat tatcaagaaa gtcaatgctg caggtaaagt tgttatcact gcaacaaaca
    12301 tgcttgaaac aatgactgaa aaaccacgtg caactcgttc agaagtatca gacgtattca
    12361 acgctgttat cgacggaact gacgctacaa tgctgtcagg cgagtctgca aacggtaaat
    12421 acccactcga gtcagtaact acaatggcta caatcgacaa gaacgctcaa gctcttctta
    12481 atgaatacgg acgtcttgat tcagattcat ttgagcgtaa ctctaagaca gaagtaatgg
    12541 cttctgctgt taaagatgct actaactcaa tggatatcaa attggttgta actcttacta
    12601 agacaggtca tactgcacgt ttgatttcta aataccgtcc aaatgctgac atcttagcat
    12661 tgacatttga cgaattgaca gaacgtggct tgatgttgaa ctggggtgtt atcccaatgt
    12721 tgacagatgc tccatcttca actgacgata tgttcgaaat cgctgaacgt aaagcggtag
    12781 aagcaggtct cgttgagtca ggcgatgata tcgttatcgt tgctggtgtg ccagtaggag
    12841 aagctgttcg cacaaacaca atgcgtatcc gcacagtacg ttaagaaaaa tataaaaacc
    12901 tatcatatcc agctttctag cctgtatgat gggctctttt tttgtccagg gggcaaaact
    12961 ttcataatgg att
//
LOCUS       DAVBOG010000054        12897 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.054, whole genome shotgun sequence.
ACCESSION   DAVBOG010000054 DAVBOG010000000
VERSION     DAVBOG010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12897
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.054"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..424)
                     /locus_tag="VQ865_001786"
                     /pseudo
     CDS             complement(1..424)
                     /locus_tag="VQ865_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001840321.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
     gene            658..807
                     /locus_tag="VQ865_001787"
     CDS             658..807
                     /locus_tag="VQ865_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001812669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136091.1"
                     /translation="MRFIVGRFTSFSLEIEFSPTSKLDDLLFKIAFLMILATWIKARK
                     TKGAT"
     gene            complement(736..1047)
                     /locus_tag="VQ865_001788"
     CDS             complement(736..1047)
                     /locus_tag="VQ865_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136092.1"
                     /translation="MIEAQGFLVDKQTRCIHYHSKLDIIALQCYDCKKYYACYRCHDS
                     LENHPFEPYPLSLIQDKPILCGVCLKLLTYKQYKESLSCPFCFSRFNPGCQNHKERYF
                     K"
     gene            complement(1062..2348)
                     /locus_tag="VQ865_001789"
     CDS             complement(1062..2348)
                     /locus_tag="VQ865_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000169115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HET3136093.1"
                     /translation="MTKTLKRPEVLSPAGTLEKLKVAVQYGADAVFIGGQAYGLRSRA
                     GNFTFEQMEEGVQFAAKYGAKVYVAANMVMHEGNEAGAGEWFRKLRDIGIAAVIVSDP
                     ALIMIAATEAPGLEIHLSTQASATNYETLEFWKELGLTRVVLAREVSMEELAEIRKRT
                     DVEIEAFVHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYDLYDMPFGKERKSL
                     QGEIPEEFSMSAVDMSMIDHIPDMIENGVDSLKIEGRMKSIHYVSTVTNCYKAAVDAY
                     LESPEKFEAIKQDLVDEMWKVAQRELATGFYYGIPSENEQLFGARRKIPEYKFVAEVV
                     SYDDATQTATIRQRNVINEGDQVEFYGPGFRHFETYIEDLHDAKGNKIDRAPNPMELL
                     TIKVPQPVQAGDMVRALKEGLINFYKEDGTSVTVRA"
     gene            2971..3153
                     /locus_tag="VQ865_001790"
     CDS             2971..3153
                     /locus_tag="VQ865_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3136094.1"
                     /translation="MANDNKSHYLIYRVLGISFEEGENIDLYQNKGRFLYKYAGSFLE
                     EAAVLSFNEKFGTENT"
     gene            3163..3513
                     /locus_tag="VQ865_001791"
     CDS             3163..3513
                     /locus_tag="VQ865_001791"
                     /inference="COORDINATES: protein motif:HMM:NF021048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ApaLI family restriction endonuclease"
                     /protein_id="HET3136095.1"
                     /translation="MPNSESTKPKTFEIDCLVGEKHAYEIKWWDATTDGDHITKEHTR
                     IKVIHNKGYIPIRLMFYYPNRTQAIKIQQTLETLYNGIGGKYYGDSAWEDLRAVTGID
                     LLSILTDIANKKQG"
     gene            3521..4711
                     /locus_tag="VQ865_001792"
     CDS             3521..4711
                     /locus_tag="VQ865_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HET3136096.1"
                     /translation="MTVLKGDNLEILKTIESSSIDLIYMDPPFFTQKTQKLSNNKNIM
                     YSFEDTWTSIEDYKEFLSVRLEECKRVLKNSGSIFVHCDKIANHHIRLILDNIFGADM
                     FQSEIIWNYKRWSNSKKGLLNNHQNIYFYSKSKDFKFNTIFTEYSSTTNIDQILVERK
                     RDGNSKTIYKVDNNGNYILAKEKNGVPLSDVWNIPFLNPKAKERVGYPTQKPILLLEQ
                     IIKIATDKNDIVLDPFCGSGTTLVASKILNRNYMGIDLSEEAINITQQRLENVIKTSS
                     DLLNKGIEAYRTKTEEEENILKLLQAKIVQRNKGIDGFLPKHFQKKPIPIKIQKNNEC
                     LNESISLLQNAINSKKLDFGVVIKTHSDNLLFDFDTIPENIIVVDHFELTIEKWLSKS
                     QQLL"
     gene            complement(5226..6218)
                     /locus_tag="VQ865_001793"
     CDS             complement(5226..6218)
                     /locus_tag="VQ865_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000122906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3136097.1"
                     /translation="MSYYDFVKDYMKVDECKNNEKYSSAGHTFCWKKENSTYAEGLYW
                     FYEGGSFIIDIHDFYIKEEVVQNSTYSMSDYVSIYSSYIVSANGEKFNPYQTITANSL
                     CTFDFDNIKDDFVFLLHENCCYLAVSIGFKKELIEKHLASININPESFYSTLLQSNQI
                     ILTKALERVAMEILNCKMDAPAADFFFKAKANEWISIVIDTYLNRKKYKIEIDDDKAL
                     EDVARFLDDHFATNVNQGTLEKISKMSGTKLKNLFKEKYCQSITEYTQRKRMNVAETL
                     LLNTELPIKEIAESVGYSSASKFSIYYKRYKGKLPSEVRNLACKHHNFKCDYCD"
     gene            6378..8132
                     /locus_tag="VQ865_001794"
     CDS             6378..8132
                     /locus_tag="VQ865_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136098.1"
                     /translation="MKIYKKLFAYVQDKKYLGVLAIIFSAISAALTVYGYYLIYKFLD
                     KLIINSNLSGAESIALKSVITLTSGAIFYFVSGMFSHILGFRLETNLRKRGIDGLEKA
                     SFRFFDLNPSGQIRKIIDDNAAQTHQVVAHMIPDSSQAIITPVLVLALGFIVSIRVGI
                     ILLALTIIGGLILGAMMGEQEFMKIYQESLSKLSAETVEYVRGMQVVKIFKANVESFK
                     SFYKAIKDYSKYAYDYSLSCKRPYVLYQWLFFGLIAILIIPIVYFMTSLASAKVILLE
                     LIMILFLSGVLFVSFMRMMWYSMYISQGNYAVDTLEALYEDMQKDKLVHGNVNNFKNY
                     NIEFENVSFAYNDKAVIENLSFNLEEGKSYALVGSSGSGKSTVAKLISGFYNVNKGSI
                     KIGGIAISEYSDEALIKAISFVFQDSKLFKKSIYDNVALANKDATKDDVMRALKLAGC
                     DLILDKFPERENTIIGSKGVYLSGGEKQRIAIARAILKDSKIIIMDEASASIDPDNEF
                     ELQKAFKNLMKDKTVIMIAHRLSTIKDLDEIIVMDSGKIIERGSDKELMSKDTRYKSL
                     QEMFNSANEWRVSNERVL"
     gene            8116..9837
                     /locus_tag="VQ865_001795"
     CDS             8116..9837
                     /locus_tag="VQ865_001795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019214631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136099.1"
                     /translation="MKEFYKKRFALTDGGARNLSKATLASFFVYCINMLPAILLMIFA
                     QEVLENMGKSNGFYIVFSVLTLIAMYILLSIEYDKLYNTTYQESADLRIRTAENLSKL
                     PLSYFSKHDISDISQTIMADIEGIEHAMSHSIPKVGGMVLFFPLISVMMLAGNVKMGL
                     AVIIPSILSFIFIPLSKKYQVNGQNRYYDVLRKNSESFQENIEMQMEIKAYNLSKDIK
                     DDLYKKMEDSERVHLKAEVTTILTLSISSIFSFISLAVVIFVGVNLIINKEINSLYLI
                     GYLLAAMKIKDSLDASKEGLMEIFYLSPKIERLKEIQNQDLQEGDDYSLKKFDIDLKD
                     VEFAYNKDAKVLNGVSFKAKQGEVTALVGASGCGKTTILKLISRLYDYDKGQILINGK
                     DIKEISTESLFDKVSIVFQDVVLFNQSVMENIRIGKQDASDEEVKRAAKLANCTDFIE
                     KMDKGFDTVIGENGAELSGGERQRLSIARAFLKDAPILILDEITASLDVNNEKKIQES
                     LNNLVKDKTVVIISHRMKSIENADKIVVLQNGRVESEGKHEELLQKSKIYKNLIEKTK
                     MAEEFIY"
     gene            9848..10432
                     /locus_tag="VQ865_001796"
     CDS             9848..10432
                     /locus_tag="VQ865_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000368966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HET3136100.1"
                     /translation="MDNKKLKVKDLVSIGVFGVIYFAFMFGVGMMGLIPILFLIYPTV
                     LAIVAGTVVMLFMAKVQKPWALFIFGMISPLVMFAAGHTYVVVVLPLIVMIIAELIRK
                     IGNYNSFKYNMLSYAIFSTWICSSLMQMLLAKEKYMEWSLMTMGKDYVDVLEKLITYP
                     HMALVALGAFLGGILGAYIGKALLKKHFEKAGIV"
     gene            10432..11127
                     /locus_tag="VQ865_001797"
     CDS             10432..11127
                     /locus_tag="VQ865_001797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001141947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3136101.1"
                     /translation="MPTFSSNAPFNPNPISKILVVFITGLTVMHSINIRFELAIVCLI
                     GILLYLNGYKKTLFKWIILCGILYSLPNFMVLSELNPIVKMFLSIPIVIRMFILPFMA
                     ASFMIKTSDVGAIISSMDKLKISKNVSIPIAVMFRFFPSFKEEKKNIKMAMRVRGINF
                     KNPVKYLEYVSVPLLIISSNISDDIAKAAETKAIENPIAKTRYIRVKIQLIDFVYVLA
                     VVGLIVGGLIWLK"
     gene            11115..12479
                     /locus_tag="VQ865_001798"
     CDS             11115..12479
                     /locus_tag="VQ865_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002837029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136102.1"
                     /translation="MVEIKNLSLDYGEEHILDDISLSIAEGECVLFTGKSGNGKSSLI
                     NSINGLAVRYDNAKTKGEIIIDGKNIKNLELYQISMLVSTVFQNPKTYFFNVNTTLEL
                     LFYLENIGLAREEMDRRLKDMLKIFPIKNLLNRNIFNLSGGEKQILCIAASYIAGTKI
                     IVMDEPSSNLDIKSISVLAKMLKILKEKGISIIVAEHRIYYLMDIVDRVFLIDKGKLK
                     KTYTRSEFLKLDKNELNALSLRDKELSKLKVPYLKEGGEYQIKNLSYKFTDDECLSLK
                     DISFKLGKIYGIIGSNGRGKSTLLRCLIGLEKKSKEEIYFKGEKLSKKERLKNSSLVM
                     QDVNHQLFTDEVFNELRLGVKNFDEEKAKIILKDLGLDEFIERHPMSLSGGQKQRLAI
                     ASVMCKTSPFVFFDEPSSGMDYSNMIKISELINKYKTMDKIIFIVSHDIEFLNEVADE
                     IFEL"
BASE COUNT         4597 a         1938 c         2201 g         4161 t
ORIGIN      
        1 cgttgacgaa tggttgctgt ttgtgtcgca tcatcataag aaatcacttc agcgacaaac
       61 ttgtactcag gaattttacg acgagcacca aacaactgct cattttcaga tggtatacca
      121 tagtaaaatc ctgtagccag ttcacgttgg gcaaccttcc acatctcgtc caccaagtct
      181 tgtttgatag cttcaaactt ttcaggactt tcaagatagg catccacagc cgccttgtag
      241 cagttggtta ctgttgatac gtagtgaata gactccactc catacgtcct tcgattttta
      301 gattgtccac accattttca atcatatctg gaatgtggtc aatcatagac atgtcaacgg
      361 ctgacattga aaattcttct ggaatctcac cctgcaaact cttacgttct ttcccaaatg
      421 gcatatcgta aaggtcgtat ttccaacggc atgactgaga acatccacca cggttggcat
      481 cacgcatact ctagacggat tgttttgaca attctaatct tttagacttt gcataataac
      541 tgttaaacag tcgaaaatta ccccagtttt aacaagtagt caaaatacca gataaaggaa
      601 aaaagtcttt aaaatcttaa aaacgcatag tatcaggtat tgaacaatct tgatattatg
      661 cgttttattg tgggaagatt tacttcattt tctcttgaaa ttgagttttc tcctacttca
      721 aaactagatg atttgctatt taaaatagcg ttccttatga ttttggcaac ctggattaaa
      781 gcgagaaaaa caaaaggggc aacttaaact ttctttatat tgcttatatg ttagtagttt
      841 tagacaaaca ccacataaaa taggcttatc ctgtatcaaa gataagggat acggctcaaa
      901 agggtgattt tctaatgaat catgacaccg ataacaagca taatactttt tacaatcata
      961 gcattgtaaa gcaataatat ccagcttgct atggtaatga atgcatcttg tttgcttatc
     1021 cactaagaaa ccctgtgcct ctatcatttc cttttccttt cttaagctcg aactgtgacg
     1081 ctggttccat cttccttata aaaattgatg agtccttctt ttaatgcacg aaccatgtct
     1141 ccagcttgaa cgggttgtgg gactttaata gtcaatagtt ccattggatt tggagcgcgg
     1201 tcgattttat tgcctttggc atcatgcaaa tcttcaatat aggtttcaaa atgacggaaa
     1261 cctggaccat aaaactcaac ttggtcccct tcgttaatga cgtttcgttg acgaatggtt
     1321 gctgtttgtg tcgcatcatc ataagaaacc acttcagcga caaacttgta ctcagggatt
     1381 ttacggcgag caccaaacaa ctgctcattt tcagatggta taccgtagta gaaacctgtt
     1441 gccaattcac gttgggcaac cttccacatc tcgtccacta agtcttgttt gatagcttca
     1501 aacttttcag gactttcaag ataggcatcc acagccgcct tgtagcagtt ggttactgtt
     1561 gatacgtagt gaatagactt catacgtcct tcgattttta gactgtccac accattttca
     1621 atcatatctg gaatgtggtc aatcatagac atgtcaacgg ctgacattga aaattcttct
     1681 ggaatctcac cctgcaaact cttacgttct ttcccaaatg gcatatcgta aaggtcgtat
     1741 ttccaacggc atgactgaga acatccacca cggttggcat cacgcatact catgtggttt
     1801 gaaagagtac aacgtccaga gtatgaaata cacatagctc catggacaaa ggcttcaatt
     1861 tcaacatctg tacgtttgcg gatctcagct aattcttcca ttgaaacctc acgcgctaaa
     1921 acgacacgag tcaagcctag ctctttccag aactcaaggg tttcatagtt agtggcactg
     1981 gcttgggtag aaaggtggat ttcaaggcct ggtgcttcag tcgctgcaat cataatcaag
     2041 gctgggtcag atacgataac tgctgcaatc ccgatatcac gcagtttacg gaaccactca
     2101 ccagcaccag cttcatttcc ttcgtgcata accatattag ccgctacata gaccttggca
     2161 ccatacttgg ccgcaaactg cacgccttct tccatctgtt cgaaagtaaa gtttcccgca
     2221 cggctacgaa gaccataggc ctgaccaccg ataaagacag catctgctcc atactgaaca
     2281 gctaccttta gcttctctaa agtccctgca ggtgataaaa cctcaggacg ttttaatgtt
     2341 tttgtcatga tttctcctat ttgcaatata aaagtttgac atttttcctt ctcattttat
     2401 agtaaataaa ggataaaatc aagcctagac ggattgtttt gacaattcta atcttttaga
     2461 ctttgcataa taactgttaa acagtcgaaa attatcccag ttttaacaag tagtcaaaaa
     2521 gtctagaaaa gtaaaaacca gtatccaaag atactgactc gtaaaaatac ataaattagt
     2581 ccttagatga ctactcccac tctgttgctc ctataatgga aaaggattga tacagtctag
     2641 aatatcgctt ttttatttat tattctgata taaaactgtt agaattgatt ttttgtttta
     2701 tacccaaata tgaatagaga cgtagctaat aagttgaata acatatttgg aaaaatgaga
     2761 aatagcaata ttactagaac ttttagaaac aatcaatatt taaaaagaaa aagctcaaag
     2821 aatttattaa accatgttat aatagatata gctataattt tatttataac aagaggatag
     2881 aaatgaccga attagaaaga aaaaatcgaa aaattagcta agaaatattc tgataactta
     2941 aacatcaaag ttcaagagag agttcgtgaa atggcaaatg ataataagag ccattatttg
     3001 atatacagag ttttaggtat ttcatttgaa gaaggagaaa atatcgattt gtatcaaaat
     3061 aaaggtcgtt ttttatacaa atatgctggt tcatttttag aagaagctgc agtactatcc
     3121 tttaacgaaa aatttggtac agaaaatact taaaaagtta acattcctaa ttctgaaagt
     3181 acaaaaccta agacttttga aattgattgt ttagtcggag aaaaacacgc atacgaaata
     3241 aaatggtggg atgcaactac agatggagac catataacta aagaacacac tagaataaaa
     3301 gttattcata acaaaggata tataccaatt cggttaatgt tctactatcc aaatagaact
     3361 caagctataa aaattcagca aactttagaa acattgtata acggtattgg agggaaatat
     3421 tatggagatt ctgcctggga agatttaaga gcagtgaccg gtattgattt acttagtatt
     3481 ctaacagata ttgcaaataa aaaacagggg taaaatcaaa atgacagtat taaaaggaga
     3541 taacttagaa atattaaaaa ctattgaatc ctcaagtatt gatttaatct atatggaccc
     3601 tcctttcttt acacagaaaa cccaaaaatt atctaataac aaaaatatta tgtattcatt
     3661 cgaagatacg tggacttcga ttgaggatta caaagaattt ttgtctgtaa gattagaaga
     3721 atgcaaaaga gtgctaaaaa atagtggcag tattttcgtt cattgtgata aaattgcaaa
     3781 tcatcatatt agattaattt tagataatat ctttggagca gatatgtttc aaagcgaaat
     3841 tatatggaac tataaacggt ggtctaattc aaaaaaggga ttattgaaca atcatcaaaa
     3901 catttacttt tattcaaagt caaaagattt taaatttaat acaattttta cagagtattc
     3961 ttctactaca aatatcgacc aaatactagt ggaacgaaaa cgagatggaa actctaaaac
     4021 tatatataaa gttgataata atggtaacta tattctagca aaagagaaaa atggagttcc
     4081 cctttcagat gtttggaata taccatttct taatccaaaa gctaaagaaa gagtaggtta
     4141 tcctacacaa aaacctattc tgttattaga acaaattata aagattgcta ctgataaaaa
     4201 tgatatagtt ttagacccgt tctgtggaag tggaactact ttagtagcct ccaagatttt
     4261 gaatagaaat tatatgggga ttgatttatc tgaggaagct atcaatataa ctcagcaacg
     4321 tctggaaaat gttataaaaa caagttcaga tttattgaat aaaggaatcg aagcatatag
     4381 aaccaaaact gaggaagagg aaaacattct taaattatta caggcaaaaa ttgttcaaag
     4441 aaataaagga attgatggtt ttttacctaa acattttcaa aaaaaaccga tacctataaa
     4501 aattcaaaaa aataatgaat gtctgaatga gagtatctct ttattacaga atgctataaa
     4561 ctccaaaaaa cttgattttg gagtagttat aaaaactcat tcagataatt tattatttga
     4621 ttttgatacg attcctgaaa atataatagt agttgaccat tttgaactta caatcgaaaa
     4681 atggttaagt aaaagtcaac agttactata gtttgcaaat tatttacaga aagaacaaaa
     4741 aatgctctga aacactgatt tcaaggcatt ttttgttagt ttaaaattac tcccattctt
     4801 cttttccaaa catacaatat atccaaaacc attcaaaata ctagattcta ttttttataa
     4861 tatcactaaa tccacctaat tataggacgt tttcagattt ttagtcccgt cccagtccca
     4921 gtaccggaga aatattgttt taatataata tctctttttg tcttctaagc tcttaaaagc
     4981 aaaagaacaa gtaaagagtc aagacaagga taaaaagtcc atattagggc aaataaaaag
     5041 ctttaagaca gatgacaaat ctaagtcaaa taagaaagac catagcaaag gtgcagagag
     5101 ataaatattg gcggtcttcg gactgccttt atttttttat ccatttttca aatcaaattt
     5161 attcagacta tatatgcaca tatacactta aattcatata aaaacatggc ttgtaaaaaa
     5221 ttactttaat cacaataatc gcatttaaaa ttgtgatgtt tgcaagctaa attacggact
     5281 tcacttggaa gttttccctt gtatctttta taatagatag aaaatttgct ggcagatgaa
     5341 tatccaacag attctgctat ctcttttata ggtagttcag tgtttaaaag aagagtttca
     5401 gctacattca ttctttttct ttgagtgtac tctgtaatgc tttgacaata tttttcctta
     5461 aataaatttt ttaatttagt accactcatt ttagatattt tttcaagcgt gccttgattt
     5521 acattcgttg caaaatgatc atctaagaat cttgctacat cttcaagtgc tttatcatca
     5581 tcaatttcaa ttttatattt ttttctattt aagtatgtgt caattactat acttatccat
     5641 tcatttgcct ttgctttaaa gaaaaaatca gcggcaggag cgtccatctt acaatttaat
     5701 atttccattg ccactctttc taaggccttt gtaagtatta tttgattcga ttgaagcaag
     5761 gttgaataaa aagattctgg attaatgtta atagatgcta aatgtttttc tattagctct
     5821 tttttaaaac caatggaaac agcaagataa caacaattct cgtgtaataa aaaaacaaaa
     5881 tcatctttta tattatcaaa atcaaaagta cataaagagt ttgcggtaat agtttgatac
     5941 ggattaaact tttctccgtt tgcactgaca atgtaacttg aataaattga aacatagtct
     6001 gacatactat aagtgctatt ttgaactact tcctctttga tataaaaatc atgtatatcg
     6061 ataatgaagc tgcctccttc ataaaaccaa tataggcctt ctgcataagt tgaattctct
     6121 tttttccaac aaaatgtatg acctgcactt gaatacttct cattgttttt acattcatct
     6181 actttcatat aatcttttac aaaatcataa tatgacataa cacactatcc cttttagaca
     6241 atattccaat tagccttatt aattcaaaac tattgtatta gtaattataa cagatgtata
     6301 atagaaaagc aatgatagat attatcaatt aagcgaattt atatctaaaa gggatattaa
     6361 agaaaggaga tatgcttatg aagatttaca aaaaactatt tgcttatgtc caagataaga
     6421 aatatcttgg ggttttggcc ataatttttt ctgctatatc tgctgcactt acagtatatg
     6481 gatattattt aatctacaaa tttctagata agttaataat taattcaaac ttatccggtg
     6541 cagagagtat agcattaaaa tctgttatta cactaacaag tggagcgata ttttattttg
     6601 tctcaggaat gttttcacat atcttgggat ttaggcttga aacaaattta agaaaaaggg
     6661 gaatcgatgg tctggaaaaa gcaagtttta ggttctttga cttaaatcca tctggtcaaa
     6721 taagaaagat catagatgat aatgcagcac aaactcatca ggtggtagca cacatgattc
     6781 ccgatagttc tcaggcaata atcacacccg tacttgtact tgcacttggc tttatagtaa
     6841 gtataagggt tggcataatt ttgcttgctc ttactataat tggtggctta attttagggg
     6901 caatgatggg cgagcaagaa tttatgaaga tataccaaga atccctatct aaactaagtg
     6961 ctgaaactgt tgagtacgtg agaggaatgc aagttgtaaa aatatttaaa gcaaatgtag
     7021 agtcttttaa aagcttttat aaggcgataa aagattactc aaagtatgct tatgattatt
     7081 ccctatcttg taaaaggcct tatgttttgt atcaatggtt attttttgga ctgattgcaa
     7141 ttttaattat tcctatagtt tattttatga ctagcttagc tagcgcaaag gtgattttac
     7201 ttgagcttat catgatttta tttttatcag gagttctctt tgtttcattc atgagaatga
     7261 tgtggtactc catgtatatt tctcaaggaa attatgcagt agatacttta gaggcgcttt
     7321 acgaagatat gcaaaaagac aaattagtgc atggtaatgt caataatttt aaaaactata
     7381 atatagaatt tgagaatgtt agctttgctt ataatgataa agctgtcatt gaaaatttat
     7441 cctttaattt agaagaagga aagtcctacg cacttgtcgg ttcatctgga tcaggcaaat
     7501 caacagtagc aaaacttata tcaggttttt acaatgttaa taaaggaagc ataaagatag
     7561 gcgggatagc aataagtgaa tattctgacg aagccttaat taaagccatt tcctttgttt
     7621 ttcaagattc aaaattattc aagaagagca tttatgataa tgtagcttta gctaataaag
     7681 atgcgacgaa agatgacgtt atgagagcct taaaattagc aggatgcgat ttaatattag
     7741 acaaattccc agaaagagaa aatacaatca taggctcaaa aggtgtttat ttatccggtg
     7801 gagaaaaaca aagaattgca attgctagag caattttaaa ggattccaaa attattatta
     7861 tggatgaagc atcagcatct attgacccag ataacgagtt tgaattgcaa aaagctttta
     7921 aaaatcttat gaaggataaa acagttatca tgattgcaca caggctatct acaattaaag
     7981 accttgatga aattattgtc atggatagtg gaaaaattat agaaagaggg tctgacaaag
     8041 aattaatgtc aaaagataca aggtataaga gcctgcaaga gatgtttaac agtgcgaatg
     8101 aatggagggt ttcaaatgaa agagttttat aaaaaaagat ttgctcttac agatggagga
     8161 gcaagaaatt taagtaaagc aacactggct tcatttttcg tttattgtat aaacatgctt
     8221 cctgccatat tacttatgat ttttgctcag gaagttttgg aaaatatggg caaaagcaat
     8281 ggcttttata tagtattctc agttttgact ttgatagcaa tgtatatttt gctttctatc
     8341 gaatacgata aattatataa cacaacctat caagaaagtg cagatttaag aataaggaca
     8401 gcggagaatt tatcaaaatt acctctatct tacttttcta aacatgacat ttccgacatt
     8461 tcacaaacaa tcatggctga tattgaaggc atagagcatg caatgagcca ctcaatacca
     8521 aaggtgggcg gcatggtact gtttttccca ttaatatctg taatgatgct agcgggcaat
     8581 gtcaagatgg gtttagctgt aattattcca tctattttaa gctttatatt tataccttta
     8641 tctaaaaaat atcaggttaa tggacagaat agatattatg atgtcttaag aaaaaactca
     8701 gaaagctttc aagaaaatat cgaaatgcaa atggagatta aagcatataa tttatcgaag
     8761 gatattaaag atgacttata taaaaaaatg gaagatagtg agagagtaca cttaaaggcg
     8821 gaagtaacta caattttaac tttgtctata tcttcaatat ttagctttat atctcttgct
     8881 gttgtgatat ttgtcggcgt aaatctaatt attaataaag agataaattc tctctacctt
     8941 ataggatatt tactagctgc tatgaagata aaagactctt tagatgcatc taaagagggc
     9001 ttgatggaaa tattttattt atcgcccaaa atagaaagat taaaagaaat tcaaaatcaa
     9061 gatctacaag aaggcgatga ctatagctta aaaaaatttg atattgatct aaaagatgtt
     9121 gagtttgcct acaataaaga cgcaaaagtt ttaaatggtg taagttttaa agctaagcag
     9181 ggagaggtca ctgctttggt aggtgcaagt ggctgcggta aaacaactat cttgaaactt
     9241 atatcaagac tttatgatta tgacaaggga caaatcttaa tcaatggcaa agatataaaa
     9301 gaaatatcaa cagaatctct ttttgataag gtctctatag ttttccaaga tgtggttctc
     9361 tttaatcaaa gcgttatgga aaatattaga atcggaaagc aagatgcaag tgacgaagag
     9421 gttaaaagag cagcaaaact tgcaaattgc acagatttta tagaaaaaat ggataaaggt
     9481 ttcgatacag ttattggtga gaacggagct gagctatcag gaggagaaag acaaagatta
     9541 tcaatagcca gagccttctt aaaagatgcg ccgatattga tcttagatga gataacagca
     9601 agccttgatg ttaacaacga gaaaaagatt caagagtctt taaataattt agttaaagat
     9661 aaaactgttg taatcatttc acatagaatg aaatccatag aaaatgcaga caagatagta
     9721 gttcttcaaa acggaagagt agaaagcgaa ggtaagcatg aagagctttt acaaaaatca
     9781 aaaatttaca aaaatttaat agaaaagaca aaaatggcag aagaatttat ttattaggag
     9841 gactacaatg gataataaaa aattaaaagt aaaagattta gtaagcatcg gtgtttttgg
     9901 cgtaatttat tttgccttca tgtttggagt tggtatgatg ggcttgattc caatattgtt
     9961 cttaatatac ccgacagtat tagccatagt tgcaggaact gttgttatgt tatttatggc
    10021 taaggttcaa aagccatggg cactatttat atttggtatg atatcaccac ttgtgatgtt
    10081 tgcagctggt catacctacg tagttgtggt tttaccactt atagtaatga taatagcaga
    10141 attaattaga aagattggta attataattc atttaaatac aatatgcttt cttatgcaat
    10201 cttcagcaca tggatatgta gctctttaat gcaaatgctt ttagcaaaag aaaaatatat
    10261 ggagtggtct ttgatgacga tgggaaaaga ttatgttgat gtattagaaa agttaataac
    10321 ttatcctcac atggctttag tagccttagg tgctttctta ggaggaattc ttggagcata
    10381 tataggcaag gctctattga aaaaacactt tgaaaaagca ggcattgtat aatgcctact
    10441 ttttcttcaa atgctccctt taatcccaat ccgatctcta agatattagt cgtatttatc
    10501 acaggcttaa ctgttatgca tagcataaac atccgttttg agctggcaat tgtttgtctt
    10561 attggtattt tgctttattt gaatggatac aaaaaaacac ttttcaaatg gattatattg
    10621 tgtgggatac tttactcctt gcctaatttt atggtgttat ctgaattaaa ccctatagtt
    10681 aagatgtttt tgagtatacc tattgttatt agaatgttta ttttaccatt tatggcagca
    10741 agctttatga taaagacctc ggatgtaggc gcaataattt catcgatgga taagcttaag
    10801 atttcaaaga atgtatccat acctattgcg gttatgttta gattcttccc atcttttaag
    10861 gaggagaaga aaaacatcaa aatggctatg agagtaagag ggataaattt taaaaaccca
    10921 gtcaaatatc ttgaatatgt ttctgtgcca ctactcatta tatcatctaa tatatcagat
    10981 gacattgcaa aagcggcaga aacaaaggca atagaaaatc caattgccaa gaccagatac
    11041 attcgcgtaa agatacagct aattgatttt gtttatgttt tagcggttgt tggacttatt
    11101 gtgggaggct taatatggtt gaaataaaaa atttaagtct tgattatggt gaagagcata
    11161 tattagatga tatatcacta tccatagccg agggagagtg cgtgctattt acaggaaaaa
    11221 gtggaaatgg taagtcatct ttaataaatt caatcaatgg actagctgta aggtatgaca
    11281 acgcaaagac aaagggcgaa atcattattg atggtaagaa tataaaaaat ttggaacttt
    11341 atcaaatctc aatgcttgtt tcaactgttt ttcaaaatcc taagacatat ttttttaatg
    11401 tcaatacgac attagaatta ttattttatt tggaaaatat cggtcttgca agagaagaga
    11461 tggacaggcg tttgaaggat atgcttaaga tattcccgat aaaaaatctt ttgaacagaa
    11521 atatatttaa tctatccggc ggtgaaaaac aaattctttg cattgcagct tcttatatag
    11581 caggtacaaa gattatagtt atggatgagc cttcatcgaa tttagatatt aaaagcataa
    11641 gtgttttggc aaagatgcta aagatattaa aagagaaagg tataagcata attgttgcag
    11701 agcatagaat ttattatttg atggacatag ttgaccgtgt atttttaata gataaaggaa
    11761 agcttaaaaa aacttatact agaagtgaat ttttaaagct agataaaaat gaattaaatg
    11821 ctttaagttt aagagataaa gaattaagta aattaaaagt tccttattta aaagaaggtg
    11881 gagagtatca gataaaaaat cttagctaca aatttactga tgatgagtgt ttaagcttaa
    11941 aagatatttc attcaagctt gggaaaattt atggcataat aggatccaac ggacgaggaa
    12001 aatcaacgct tttaagatgt ttaataggtc ttgagaaaaa atcaaaagaa gaaatttatt
    12061 ttaagggaga gaagctatct aaaaaagaaa gactcaaaaa ctcttcactt gttatgcaag
    12121 atgtaaatca tcaattattc acagatgaag tattcaacga gcttagatta ggagtaaaga
    12181 attttgatga agaaaaggcg aaaatcattt taaaagattt aggcctggac gaatttattg
    12241 aaaggcatcc gatgagttta tcaggagggc aaaagcaaag gcttgcaata gcatctgtta
    12301 tgtgcaagac ttctccattt gtcttttttg acgaaccttc aagtggtatg gattattcca
    12361 atatgataaa aatatctgaa ctgattaata agtataaaac catggataaa ataattttta
    12421 ttgtttccca tgatatagaa tttttaaatg aagtggcaga tgaaattttt gaattgtaaa
    12481 atagagtctg ttaaacatgt ctatagaact agtaaattgt ctaaaaattt aaaagatact
    12541 aacacatatt gatatttatt agaaaattaa cttcaggatt tttacagtat ttataaactt
    12601 tataatatgt atttatagta ttaataattt ccatatcttt agggaaattc tttatttact
    12661 taccataatt aaagagatga gagataaata tcggcagtct tcggactgcc tttatttttt
    12721 tacttaattt aatgcagtaa atcatacgat tgaaaggaat ctgcgttata tgctataatt
    12781 aggtggttaa tctatacatt tagaaaggta aaatatagaa ttggagaatg atatgggatt
    12841 ttcatataat aaattgtaac cgtccaataa cgaagtatat tgaaaaatct ccagact
//
LOCUS       DAVBOG010000055        12043 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.055, whole genome shotgun sequence.
ACCESSION   DAVBOG010000055 DAVBOG010000000
VERSION     DAVBOG010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12043
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.055"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            371..598
                     /locus_tag="VQ865_001799"
     CDS             371..598
                     /locus_tag="VQ865_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000576349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136103.1"
                     /translation="MIFKAFKTKKQRKRQVELLLTVFFDSFLIDLFLHLFGIVPFKLD
                     KILIVSLIIFPIISTSIYAYEKLFEKVFDKD"
     gene            886..4023
                     /gene="nanA"
                     /locus_tag="VQ865_001800"
     CDS             886..4023
                     /gene="nanA"
                     /locus_tag="VQ865_001800"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored neuraminidase NanA"
                     /protein_id="HET3136104.1"
                     /translation="MNRSIQERKCRYSIRKLSVGAVSMIVGAVVFGTSPVLAQEGASE
                     QPLANETQLSGGSSTLTDTEKSQPSSETELSGNKQEQERKDKQEEKIPRDYYARDLEN
                     VETVIEKEDVETNASNGQRVDLSSELDKLKKLENATVHMEFKPDASAPRFYNLFSVSS
                     DTKENEYFTMSVLDNTALIEGRGANGEQFYDKYTDAPLKVRPGQWNSVTFTVEQPTAE
                     LPHGRVRLYVNGVLSRTSLKSGNFIKDMPDVNQAQLGATKRGNKTVWGSNLQVRNLTV
                     YDRALSPEEVQTRSQLFERGDLEKKLPEGAKISEKEDVFEGGMNNKPNKDGIKSYRIP
                     ALLKTDKGTLIAGADERRLHSSDWGDIGMVIRRSEDNGKTWGDRVTITNLRDNPKASD
                     PSIGSPVNIDMVLVQDPETKRIFSIYDMFPEGKGIFGMSSQKEEAYKKIDGKTYQILY
                     REGEKGAYTIRENGTVYTPDGKATDYRVVVDPVKPAYSDKGDLYKGDQLLGNIYFTTN
                     KTSPFRIAKDSYLWMSYSDDDGKTWSAPQDITPMVKADWMKFLGVGPGTGIVLRNGPH
                     KGRILIPVYTTNNVSHLDGSQSSRVIYSDDHGKTWHAGEAVNDNRQVDGQKIHSSTMN
                     NRRAQNTESTVVQLNNGDVKLFMRGLTGDLQVATSKDGGVTWEKDIKRYPQVKDVYVQ
                     MSAIHTMHEGKEYIILSNAGGPKRENGMVHLARVEENGELTWLKHNPIQKGEFAYNSL
                     QELGNGEYGILYEHTEKGQNAYTLSFRKFNWEFLSKNLISPTEAKVKRTREMGKGEMG
                     KGVIGLEFDSEVLVNKAPTLQLANGKTARFMTQYDTKTLLFTVDSEDMGQKVTGLAEG
                     AIESMHNLPVSVAGTKLSNGMNGSEAAVHEVPEYTGPLGTSGEEPAPTVEKPEYTGPL
                     GTSGEEPAPTVEKPEYTGPLGTSGEEPAPTVEKPEYTGPLGTAGEEAAPTVEKPEFTG
                     GVNGTEPAVHEIAEYKGSDSLVTLTTKKDYTYKAPLAQQALPETGNKESDLLASLGLT
                     AFFLGLFTLGKKREQ"
     gene            5038..5490
                     /locus_tag="VQ865_001801"
     CDS             5038..5490
                     /locus_tag="VQ865_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HET3136105.1"
                     /translation="MIITKISRLGTYVGVNPHFATLIDFLEKTGLENLTEGSIAIDGN
                     RLFGNCFIYLADGQAGAFFETHQKYLDIHLVLENEEAMAVTSPENVSVTQEYDEEKDI
                     ELYTGKVEQLVHLRAGECLITFPEDLHQPKVRINDEPVKKVVFKVAIS"
     gene            5509..6846
                     /locus_tag="VQ865_001802"
     CDS             5509..6846
                     /locus_tag="VQ865_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HET3136106.1"
                     /translation="MKKMRKFLCLAGIALAAVALVACSGKKEATTSTEPPTELSGEIT
                     MWHSFTQGPRLESIQKSADAFIQKHPKTKIKIETFSWNDFYTKWTTGLANGNVPDIST
                     ALPNQVMEMVNSDALVPLNDSIKRIGQDKFNETALNEAKIGDDYYSVPLYSHAQVMWV
                     RTDLLKEHNIEVPKTWDQLYEASKKLKEAGVYGLSVPFGTNDLMATRFLNFYVRSGGG
                     SLLTKDLKADLTSQLAQDGIKYWVKLYKEISPQDSLNFNVLQQATLFYQGKTAFDFNS
                     GFHIGGINANSPQLIDSIDAYPIPKIKESDKDQGIETSNIPMVVWKNSKHPEVAKAFL
                     EALYNEEDYVKFLDSTPVGMLPTIKGISDSAAYKENETRKKFKHAEEVITEAVKKGTA
                     IGYENGPSVQAGMLTNQHIIEQMFQDIITNGTDPMKAAKEAEKQLNDLFEAVQ"
     gene            6925..7809
                     /locus_tag="VQ865_001803"
     CDS             6925..7809
                     /locus_tag="VQ865_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HET3136107.1"
                     /translation="MVKERNLTRWIFVLPAMIIVGLLFVYPFFSSIFYSFTNKHLIMP
                     NYKFVGLANYKAVLSDPNFFNAFFNSIKWTVFSLVGQVLVGFVLALALHRVRHFKKLY
                     RTLLIVPWAFPTIVIAFSWQWILNGVYGYLPNLIVKLGLMEHTPAFLTDSTWAFLCLV
                     FINIWFGAPMIMVNVLSALQTVPEEQFEAAKIDGASSWQVFKFIVFPHIKVVVGLLVV
                     LRTVWIFNNFDIIYLITGGGPANATTTLPIFAYNLGWGTKLLGRASAVTVLLFIFLVA
                     ICFIYFAIISKWEKEGRK"
     gene            7809..8642
                     /locus_tag="VQ865_001804"
     CDS             7809..8642
                     /locus_tag="VQ865_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HET3136108.1"
                     /translation="MKKKSSIYLDILSHVLLVGATIVAVFPLVWIIISSVKGKGELTQ
                     YPTRFWPEQFTLDYFTHVINDLHFIDNIRNSLIIALATTLIAIIISAMAAYGIVRFFP
                     KLGAIMSRLLVITYIFPPILLAIPYSIAIAKVGLTNSLFGLMMVYLSFSVPYAVWLLV
                     GFFQTVPIGIEEAARIDGANKFVTFYKVVLPIVAPGIVATAIYTFINAWNEFLYALIL
                     INNTGKMTVAVALRSLNGSEILDWGDMMAASVIVVLPSIIFFSIIQNKIASGLSEGSV
                     K"
     gene            8660..10753
                     /gene="nanB"
                     /locus_tag="VQ865_001805"
     CDS             8660..10753
                     /gene="nanB"
                     /locus_tag="VQ865_001805"
                     /EC_number="3.2.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neuraminidase NanB"
                     /protein_id="HET3136109.1"
                     /translation="MNKRGLYSKLGISVVGISLLMGVPTLIHANELNYGQLSISPIFQ
                     GGSYQLNNKSIDISSLLLDKLSGESQTVVMKFKADEPNSLQALFGLSNSKADFKNNYF
                     SIFMRDSGEIGVEIRDAQKGINYLFSRPASLWGKHKGQAVENTLVFVSDSKDKTYTMY
                     VNGIEVFSETVDTFLPISNINGIDKATLGAVNREGKEHYLAKGSIDEISLFNKAISDQ
                     EVSTIPLSNPFQLIFQSGDSTQANYFRIPTLYTLSSGRVLSSIDARYGGTHDSKSKIN
                     IATSYSDDNGKTWSEPIFAMKFNDYEEQLVYWPRDNKLKNSQISGSASFIDSSIVEDK
                     KSGKTILLADVMPAGIGNNNANKADSGFKEINGHYYLKLKKNGDNDFRYTVRENGVVY
                     NETTNKPTNYTINDKYEVLEGGKSLTVEQYSVDFDSGSLRERHNGKQVPMNVFYKDSL
                     FKVTPTNYIAMTTSQNRGESWEQFKLLPPFLGEKHNGTYLCPGQGLALKSSNRLIFAT
                     YTSGELTYLISDDSGQTWKKSSASIPFKNATAEAQMVELRDGVIRTFFRTTTGKIAYM
                     TSRDSGETWSKVSYIDGIQQTSYGTQVSAIKYSQLIDGKEAVILSTPNSRSGRKGGQL
                     VVGLVNKEDDSIDWKYHYDIDLPSYGYAYSAITELPNHHIGVLFEKYDSWSRNELHLS
                     NVVQYIDLEINDLTK"
     gene            10765..11868
                     /locus_tag="VQ865_001806"
     CDS             10765..11868
                     /locus_tag="VQ865_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000241731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3136110.1"
                     /translation="MVKYGVVGAGYFGAELARYMQKNDGAEITLLYDPDNAEAIAEEL
                     GAKVASSLDELVSSDEVDCVIVATPNNLHKEPVIKAAQHGKNVFCEKPIALSYQDCRE
                     MVDACKENNVTFMAGHIMNFFNGVHHAKELINQGVIGDVLYCHTARNGWEEQQPSVSW
                     KKIREKSGGHLYHHIHELDCVQFLMGGMPETVTMTGGNVAHEGEHFGDEDDMIFVNME
                     FSNKRFALLEWGSAYRWGEHYVLIQGSKGAIRLDLFNCKGTLKLDGQESYFLIHESQE
                     EDDDRTRIYHSTEMDGAIAYGKPGKRTPLWLSSVIDKEMRYLHEIMEGAPVSEEFAKL
                     LTGEAALEAIATADACTQSMFEDRKVKLSEIVK"
BASE COUNT         4056 a         1917 c         2523 g         3547 t
ORIGIN      
        1 gtcagtctta tctacaacct caaaacagtg ttttgagcat catgcggcta gcttcttagt
       61 ttgctctttg attttcattg agtataaaaa cagatgagtt tctgttttct ttttatggac
      121 tataaatgtt cagctgaaac tactttcaag gacattatta tataaaagaa ttttttgaaa
      181 ctaaaatcta ctatattaca ctatattgaa agcgttttaa aaatgaggta taataaattt
      241 actaacgctt ataaaaagtg atagaatcta tctttatgta tatttaaaga tagattgctg
      301 taaaaatagt agtagctatg cgaaataaca gatagagaga agggattgaa gcttagaaaa
      361 ggggaataat atgatattta aggcattcaa gacaaaaaag cagagaaaaa gacaagttga
      421 actacttttg acagtttttt tcgacagttt tctgattgat ttatttcttc acttatttgg
      481 gattgtcccc tttaagctgg ataagattct gattgtgagc ttgattatat ttcccattat
      541 ttctacaagt atttatgctt atgaaaagct atttgaaaaa gtgttcgata aggattgagc
      601 aggaagtatg gtataaatag cataagctga tgtccatcat ttgcttataa agagatattt
      661 tagtttaatt gcagcggtgc cctggtagat aaactagatt ggcaggagtc tgattggaga
      721 aaggagaggg gaaaattggc accaatttga gatagtttgt ttagttcatt tttgtcattt
      781 aaatgaactg tagtaaaaga aagttaataa aagacaaact aagtgcattt tctggagtaa
      841 atgtcttatt tcagaaatcg ggatatagat atagagagga tcagtatgaa tcggagtatt
      901 caagaacgta agtgtcgtta tagcattagg aaactatcgg taggagcggt ttctatgatt
      961 gtaggagcag tggtatttgg aacgtctcct gttttagctc aagaaggggc aagtgagcaa
     1021 cctctggcaa atgaaactca actttcgggg gggagctcaa ccctaactga tacagaaaag
     1081 agccagcctt cttcagagac tgaactttct ggcaataagc aagaacaaga aaggaaagat
     1141 aagcaagaag aaaaaattcc aagagattac tatgcacgag atttggaaaa tgtcgaaaca
     1201 gtgatagaaa aagaagatgt tgaaaccaat gcttcaaatg gtcagagagt tgatttatca
     1261 agtgaactag ataaactaaa gaaacttgaa aacgcaacag ttcacatgga gtttaagcca
     1321 gatgcatcag ctccacgctt ttacaatctc ttctctgtat ccagtgacac caaggaaaat
     1381 gagtacttta ctatgtcggt ccttgataat acagctctta ttgaagggcg tggcgctaac
     1441 ggagagcagt tctatgataa gtatacagat gctcctttga aagttcgccc aggacaatgg
     1501 aattccgtga cctttactgt cgaacaaccg acagcggagt tacctcatgg acgagttcgt
     1561 ctctatgtga acggtgtctt atctcgaaca agtctcaaat ctggtaactt tatcaaagat
     1621 atgccagatg ttaatcaagc tcaacttgga gcaaccaaac ggggcaataa gacagtttgg
     1681 ggaagcaatc tacaagttcg aaacctaacc gtctatgatc gtgccttaag cccagaagaa
     1741 gttcagacga gaagccaact atttgaaaga ggtgatttgg agaagaaact tccagaaggt
     1801 gcgaaaatct cagagaaaga agacgtcttt gaagggggaa tgaacaacaa accaaataaa
     1861 gatggaatta agagttatcg tattccagct cttctcaaga cagataaagg aactttgatc
     1921 gcaggtgcag atgaacgccg tctccattcg agtgactggg gtgatatcgg tatggtcatc
     1981 agacgtagtg aagataatgg taaaacttgg ggtgaccgag taaccattac caacttacgt
     2041 gacaatccaa aagcttctga cccatcgatc ggttcaccag tgaatatcga tatggtgttg
     2101 gttcaagatc ctgaaaccaa acgaatcttt tctatctatg acatgttccc agaagggaag
     2161 ggaatctttg gaatgtcttc acaaaaagaa gaagcctaca aaaaaatcga tggaaaaacc
     2221 tatcaaatcc tctaccgtga aggagaaaag ggagcttata ccattcgaga aaatggtact
     2281 gtctatacac cagatggtaa ggcgacagac tatcgcgttg ttgtagatcc tgttaaacca
     2341 gcctatagcg acaagggtga tctatacaag ggtgaccaat tactaggaaa tatctacttc
     2401 acaacaaaca aaacttctcc atttagaatt gccaaggata gctatctatg gatgtcctac
     2461 agtgatgacg acgggaagac atggtcagct cctcaagata ttactccgat ggtcaaagcc
     2521 gattggatga aattcttggg tgtaggtcct ggaacaggaa ttgtacttcg gaatgggcct
     2581 cacaagggac ggattttgat accggtttat acgactaata atgtatctca cttagatggc
     2641 tcgcaatctt ctcgtgtcat ctattcagat gatcatggaa aaacttggca tgctggagaa
     2701 gcggtcaacg ataaccgtca ggtagacggt caaaagatcc actcttctac gatgaacaat
     2761 agacgtgcgc aaaatacaga atcaacggtg gtacaactaa acaatggaga tgttaaactc
     2821 tttatgcgtg gtttgactgg agatcttcag gttgctacaa gtaaagacgg aggagtgact
     2881 tgggagaagg atatcaaacg ttatccacag gttaaagatg tctatgttca aatgtctgct
     2941 atccatacga tgcacgaagg aaaagaatac atcatcctca gtaatgcagg tggaccgaaa
     3001 cgtgaaaatg ggatggtcca cttggcacgt gtcgaagaaa atggtgagtt gacttggctc
     3061 aaacacaatc caattcaaaa aggagagttt gcctataatt cgctccaaga attaggaaat
     3121 ggggagtatg gcatcttgta tgaacatact gaaaaaggac aaaatgccta taccctatca
     3181 tttagaaaat ttaattggga atttttgagc aaaaatctga tttctcctac cgaagcgaaa
     3241 gtgaagcgaa ctagagagat gggcaaagga gagatgggca aaggagttat tggcttggag
     3301 ttcgactcag aagtattggt caacaaggct ccaacccttc aattggcaaa tggtaaaaca
     3361 gcacgcttca tgacccagta tgatacaaaa accctcctat ttacagtgga ttcagaggat
     3421 atgggtcaaa aagttacagg tttggcagaa ggtgcaattg aaagtatgca taatttacca
     3481 gtctctgtgg cgggcactaa gctttcgaat ggaatgaacg gaagtgaagc tgctgttcat
     3541 gaagtgccag aatacacagg cccattaggg acatccggcg aagagccagc cccgacagtc
     3601 gagaagccag aatatacagg tccattaggg acatccggtg aagagccagc tccaacagtc
     3661 gagaagccag aatacacagg cccactaggg acatccggcg aagagccagc cccgacagtc
     3721 gagaagccag aatacacagg cccactaggg acagctggtg aagaagcagc tccaacagtc
     3781 gagaagccag aatttacagg gggagttaat ggtacagagc cagctgttca tgaaatcgca
     3841 gagtataagg gatctgattc gcttgtaact cttactacaa aaaaagatta tacttacaaa
     3901 gctcctcttg ctcagcaggc acttcctgaa acaggaaaca aggagagtga cctcctagct
     3961 tcactaggac taacagcttt cttccttggt ctgtttacgc tagggaaaaa gagagaacaa
     4021 taagagaaga attctaaaca tttgattttg taaaaataga aggagatagc aggttttcaa
     4081 gcctgctatc tttttttgat gacattcagg ctgatacgaa atcataagag gtctgaaact
     4141 actttcagag tagtctgttc tataaaatat agtagattga aataagatgt gaacaactct
     4201 atcaggaaag tcaaattaat ttatagaaaa attttagcag tcaaggtgta ctgttataga
     4261 ttcaatatat tatgcgacta ttaaccttgt cttctcctaa aattgacttt cttgttttct
     4321 tatcttgtcc actcgaaaca agtattgtaa gaatttgatt atttttgaaa gtacttttaa
     4381 tatacttgat atagttaaaa aagatttgaa actaaattcc aaattagaaa aagacttgaa
     4441 atactaaaaa aaaaaagtat actctaattg aaaacggtaa caaaactaat ttagagaatg
     4501 aaatatagag tatttctctc ttaaaagttt ttggtgaaac gagatgtaga aaggagattt
     4561 agccaaagag tctattagtg ctagaataat agattagaat tattttagaa aaacgaagtg
     4621 agcagcttat aaattcaagt ccccaaatag attcatacta gtatcttttg caaaaaataa
     4681 agggcgactt ccttcatgaa tatcaatttc atctataagg aaggtagcta attgaactaa
     4741 cttatttatt ctgtttgtcg ctagaaaaat cagacctcct tgtgaagatt gaggagatac
     4801 tgaatgaaaa tcaaagaaga aactagcaag ctagtagcag attgcccaaa acaccgcttt
     4861 gaggttgtag ataagactga cgtatataat ccaaggtgaa gcgactgtgg tttgaagaga
     4921 ttttcaaaga gtataggcta gagagtagtg tttttatgtc cttctagtag aaaatgctag
     4981 acagaagaat ggggaacttg gataggaaaa atagattgag aaaggaggtt agaagagatg
     5041 attattacaa aaattagccg tttaggaact tatgtgggag tcaatccaca ttttgcaaca
     5101 ttaatagatt ttctagaaaa aacaggacta gaaaatttaa cagaaggttc gattgctatc
     5161 gatggtaatc gattgtttgg gaattgcttt atttatctag cagatggtca agcaggggct
     5221 ttctttgaaa cacaccaaaa atatttggat attcatttag ttttggaaaa cgaagaagcc
     5281 atggctgtta catcgccgga aaatgtaagc gttacccaag aatatgatga agagaaagat
     5341 attgaattat acacagggaa agtggaacag ttggttcatt tgagagctgg tgaatgcctc
     5401 atcacttttc cagaagattt acatcaaccc aaggttcgta taaatgatga acctgtgaaa
     5461 aaagttgtct ttaaagttgc gatttcttaa tgtagaaaga gaagaacgat gaaaaaaatg
     5521 agaaagtttt tatgtctagc tggaattgcg ctagcggctg ttgccttggt agcttgttca
     5581 ggaaaaaaag aagctacaac tagtactgaa ccaccaacag aattatctgg tgagattaca
     5641 atgtggcact cctttactca aggaccccgt ttagaaagta ttcaaaaatc agcagatgct
     5701 ttcatacaaa agcatccaaa aacgaaaatc aagattgaaa cattttcttg gaatgacttc
     5761 tatactaaat ggactacagg tttagcaaat ggaaatgtgc cagatatcag tacagctctt
     5821 cctaaccaag taatggaaat ggtcaactca gatgctttgg ttccgctaaa tgattctatc
     5881 aagcgtattg gacaagataa atttaacgaa actgccttaa atgaagcaaa aatcggagat
     5941 gattactact ctgttcctct ttattcacat gcacaagtca tgtgggttag aacagatttg
     6001 ttaaaagaac ataatattga ggttcctaaa acttgggatc aactctatga agcttctaaa
     6061 aaattgaaag aagctggagt ttatggcttg tctgttccgt ttggaacaaa tgacttaatg
     6121 gcaacacgtt tcttgaactt ctacgtacgt agtggtggag gaagcctctt aacaaaagat
     6181 cttaaagcag acttgacaag ccaacttgct caagatggta ttaaatactg ggttaaattg
     6241 tataaagaaa tctcacctca agattctttg aattttaatg tccttcaaca agctaccttg
     6301 ttctatcaag gaaaaacagc atttgacttt aactctggct tccatatcgg aggaattaat
     6361 gccaacagtc ctcaattgat tgattcgatt gatgcttatc ctattccaaa aatcaaagag
     6421 tctgataaag accaaggaat tgaaacctca aacattccaa tggttgtttg gaaaaattca
     6481 aaacatccag aagttgctaa agcattctta gaagcacttt ataatgaaga agactacgtt
     6541 aaattccttg attcaactcc agtaggtatg ttgccaacta ttaaggggat tagcgattct
     6601 gcagcctata aagaaaatga aactcgtaag aagtttaaac atgctgaaga agtaattact
     6661 gaagctgtta aaaaaggtac tgctattggt tatgaaaatg gaccaagtgt acaagctggt
     6721 atgttgacta accaacacat tattgaacaa atgttccaag atatcattac aaatggaaca
     6781 gatcctatga aagcagcaaa agaagcagaa aaacaattaa acgatttatt tgaggctgtt
     6841 cagtagatgt aaaagactag aaaataggtg ggctagtgat ctgaaaagct ctagcccaat
     6901 tttgtaaaag aagggagaag gagaatggtt aaagaacgta atttaactcg ctggatattt
     6961 gttttgccag ctatgattat cgtaggatta ctctttgttt atccgttttt ctcgagtatt
     7021 ttttatagct ttaccaataa gcatttgatt atgcctaatt ataaatttgt tggtttggct
     7081 aactataaag ctgtgctatc agatcccaac ttctttaatg cgttctttaa ttcaattaag
     7141 tggaccgttt tctcattagt tggtcaagtt ttagtagggt ttgtgttggc tttagctctt
     7201 cacagagtac gccacttcaa gaaattatat aggaccttat tgattgttcc ttgggcattt
     7261 cctaccatcg ttattgcctt ctcttggcag tggattctaa acggggttta tggctactta
     7321 cctaatctaa tcgtaaaatt aggtttaatg gaacatacac ctgcattttt gacagatagt
     7381 acatgggcat tcctatgttt ggtgtttatc aacatttggt ttggagcacc aatgattatg
     7441 gttaatgtgc tttcagcttt gcaaacagta ccagaagaac aatttgaggc tgctaagata
     7501 gatggtgctt caagttggca ggtgttcaag tttatcgtct ttccacatat taaagtggtt
     7561 gtaggacttc tagttgtttt gagaactgta tggatcttta ataactttga cattatctac
     7621 ctcattactg gtggtggacc agccaatgct acaacgacgc ttccaatttt tgcttacaac
     7681 ctgggttggg gaactaaatt gttgggtcgt gcttcagcag ttacagtatt gctctttatc
     7741 ttcttggtgg cgatttgctt tatctacttt gctatcatca gtaagtggga aaaggagggt
     7801 agaaaataat gaagaagaaa tccagtattt atttagatat tctctcacat gtacttttag
     7861 ttggtgcgac catcgttgca gttttcccat tggtatggat tatcatatct tctgtcaaag
     7921 ggaaagggga attaactcag tatccaacac gattttggcc tgaacagttt acattagatt
     7981 atttcactca tgttatcaac gatttgcact tcattgataa cattcgaaac agtttaatca
     8041 ttgccttggc tacaaccctc attgcgatta ttatttctgc tatggcagcc tatggtattg
     8101 ttcgattctt tcctaaattg ggagcaatca tgtcgagact actcgtcatt acctatattt
     8161 tcccaccaat tttgttagca attccctatt caattgccat tgctaaagtt gggttaacaa
     8221 atagtttatt tggcttgatg atggtttatc tatcttttag tgttccatat gcagtttggc
     8281 tcttagttgg atttttccaa acagttccaa ttggaattga agaagcggct agaattgatg
     8341 gtgcaaataa atttgttacg ttttataaag ttgtgctacc gattgtagca ccaggtattg
     8401 tagcaacagc tatttataca tttatcaatg cttggaatga attcctgtat gccttgattt
     8461 tgattaacaa tacaggaaag atgacagtag cagtagccct tcgttcactt aatggttcag
     8521 aaatactaga ctggggagat atgatggcag cgtctgttat tgtagttctt ccatcaatta
     8581 ttttcttctc tatcatccaa aataagattg caagtggatt atcagaagga tctgtgaagt
     8641 agacgaaaga aggaaaaaaa tgaataaaag aggtctttat tcaaaactag gaatttctgt
     8701 tgtaggcatt agtcttttaa tgggagttcc cactttgatt catgcgaatg aattaaacta
     8761 tggtcaactg tccatatctc ctatttttca aggaggttca tatcaactga acaataagag
     8821 tatagatatc agctctttgt tattagataa attgtctgga gagagtcaga cagtagtaat
     8881 gaaatttaaa gcagatgaac caaactctct tcaagctttg tttggcctat ctaatagtaa
     8941 agcagacttt aaaaataatt acttttcaat tttcatgaga gattctggtg agataggtgt
     9001 agaaataaga gacgcccaaa agggaataaa ttatttattt tccagaccag cttcattatg
     9061 gggaaaacat aaaggacagg cagttgaaaa tacactagta tttgtatctg attctaaaga
     9121 taaaacatac acaatgtatg ttaatggaat agaagtgttc tctgaaacag ttgatacatt
     9181 tttgccaatt tcaaatataa atggtataga taaggcaaca ctaggagctg ttaatcgtga
     9241 aggtaaggaa cattacctcg caaaaggaag tattgatgaa atcagtctat ttaacaaagc
     9301 aattagtgat caggaagttt caactattcc cttgtcaaat ccatttcagt taattttcca
     9361 atcaggagat tctactcaag ctaactattt tagaataccg acactatata cattaagtag
     9421 tggaagagtt ctatcaagta ttgatgcacg ttatggtggg actcatgatt ctaaaagtaa
     9481 gattaatatt gccacttctt atagtgatga taatgggaaa acgtggagtg agccaatttt
     9541 tgctatgaag tttaatgact atgaggagca gttagtttac tggccacgag ataataaatt
     9601 aaagaatagt caaattagtg gaagtgcttc attcatagat tcatccattg ttgaagataa
     9661 aaaatctggg aaaacgatat tactagctga tgttatgcct gcgggtattg gaaataataa
     9721 tgcaaataaa gccgactcag gttttaaaga aataaatggt cattattatt taaaactaaa
     9781 gaagaatgga gataacgatt tccgttatac agttagagaa aatggtgtcg tttataatga
     9841 aacaactaat aaacctacaa attatactat aaatgataag tatgaagttt tggagggagg
     9901 aaagtcttta acagtcgaac aatattcggt tgattttgat agtggctctt taagagaaag
     9961 gcataatgga aaacaggttc ctatgaatgt tttctacaaa gattcgttat ttaaagtgac
    10021 tcctactaat tatatagcaa tgacaactag tcagaataga ggagagagtt gggaacaatt
    10081 taagttgttg cctccgttct taggagaaaa acataatgga acttacttat gtcccggaca
    10141 aggtttagca ttaaaatcaa gtaacagatt gatttttgca acatatacta gtggagaact
    10201 aacctatctc atttctgatg atagtggtca aacatggaag aaatcctcag cttcaattcc
    10261 gtttaaaaat gcaacagcag aagcacaaat ggttgaactg agagatggtg tgattagaac
    10321 attctttaga accactacag gtaagatagc ttatatgact agtagagatt ctggagaaac
    10381 atggtcgaaa gtttcgtata ttgatggaat ccaacaaact tcatatggca cacaagtatc
    10441 tgcaattaaa tactctcaat taattgatgg aaaagaagca gtcattttga gtacaccaaa
    10501 ttctagaagt ggccgtaagg gaggtcaatt agttgtcggt ttagtcaata aagaagatga
    10561 tagtattgat tggaaatacc actatgatat tgatttgcct tcgtatggtt atgcctattc
    10621 tgcgattaca gaattgccaa atcatcacat aggtgtactg tttgaaaaat atgattcgtg
    10681 gtcgagaaat gaattgcatt taagcaatgt agttcagtat atagatttgg aaattaatga
    10741 tttaacaaaa taaaggagaa aaacatggtt aaatacggtg ttgttggagc agggtatttt
    10801 ggagctgaat tggctcgcta catgcaaaag aatgatggag cagagattac tcttctctat
    10861 gatccagata atgcagaggc gattgcagaa gaattggggg caaaagtagc aagttcctta
    10921 gatgagttgg tttctagcga tgaagtagat tgtgttatcg tcgcaactcc aaataatctt
    10981 cataaggaac cggttattaa ggctgcacag catggtaaaa atgttttctg tgaaaaacca
    11041 attgcgcttt cttatcaaga ttgtcgcgag atggtagatg cgtgtaaaga aaacaatgta
    11101 acctttatgg caggacatat tatgaatttc tttaatggtg ttcatcatgc aaaagaactc
    11161 attaatcaag gagttatcgg agacgttcta tattgtcata cagctcgtaa tggttgggaa
    11221 gaacaacaac cgtcagtatc atggaaaaaa attcgtgaaa aatcaggtgg tcacttgtat
    11281 caccacatcc atgaattgga ttgcgttcaa ttccttatgg ggggcatgcc tgaaactgta
    11341 accatgacag gtggaaatgt ggcccatgaa ggtgaacatt tcggtgatga agatgatatg
    11401 atttttgtca atatggaatt ttctaataag cgttttgcct tgttagaatg gggttcagct
    11461 tatcgttggg gtgaacatta tgtcttaatc caaggaagca aaggtgccat ccgcttagac
    11521 ttattcaact gtaaaggaac tcttaagcta gatgggcaag aaagctattt cttgattcac
    11581 gaatcgcaag aagaagatga tgatcggact cgtatctatc atagtacaga gatggatgga
    11641 gcaattgctt atggtaaacc aggtaaacgt actccattat ggctatcatc tgtcattgat
    11701 aaagaaatgc gctatctgca tgagattatg gaaggagctc cagtatcaga agaatttgca
    11761 aaacttttga caggtgaagc tgccctagaa gcaattgcta ctgcagatgc ttgtacccag
    11821 tctatgtttg aagatcgcaa agtaaaattg tcagaaattg taaaataaat tttggtattc
    11881 tcctattata ggtcgacttg ctcctctgaa agtactttta gaggagctgt ttgactttgc
    11941 tagtttttga aactgaaatc tattatacta caaactattg aaagcgtttt aattttaagg
    12001 tataataatc tcatagaaat aaagaaaagg aggaaagagg atg
//
LOCUS       DAVBOG010000056        12027 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.056, whole genome shotgun sequence.
ACCESSION   DAVBOG010000056 DAVBOG010000000
VERSION     DAVBOG010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 12027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12027
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.056"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..207)
                     /locus_tag="VQ865_001807"
     CDS             complement(<1..207)
                     /locus_tag="VQ865_001807"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136111.1"
                     /translation="MENMTNHLLLVQIRVHGYLLDFASSEGQRQKHYRLKNLPQTVEL
                     TVDDVEEDVDLTLPENRSYQEADFF"
     gene            complement(275..916)
                     /locus_tag="VQ865_001808"
     CDS             complement(275..916)
                     /locus_tag="VQ865_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136112.1"
                     /translation="MIDIQGLEKKFNDRAIFSGLNLKLEKGKVYALIGKSGSGKTTLL
                     NILGKLEKIDGGRVLYQGKDLKTIPTREYFRDQMGYLFQNFGLLENQSIKENLDLGFV
                     GQKISKVERLERQVGALEKVNLGYLDLEQKIYTLSGGEAQRVALAKTILKNPPLILAD
                     EPTAALDPENSEEVMNLLVDLKDENRIIIIATHNPLVWNKADEIIDMRKLAHV"
     gene            complement(918..2947)
                     /locus_tag="VQ865_001809"
                     /pseudo
     CDS             complement(918..2947)
                     /locus_tag="VQ865_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000825281.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin-associated integral membrane family
                     protein"
     gene            complement(3216..4115)
                     /locus_tag="VQ865_001810"
     CDS             complement(3216..4115)
                     /locus_tag="VQ865_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000904853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3136113.1"
                     /translation="MLIGQKIKEIRIEKGISRPDFCGDEQELTVRQLSRIESGASQPS
                     LPKLDYIARRLGVPVYSLMPDFSALPPAYLELKYQILREPIYGKEEEYDKKEACLEEI
                     YKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEVYSTNDMLL
                     IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVG
                     VTDCFNDYLSCLQEIMDKTQDYQKKPLVFMFLWKQALREERDFSLAESFYQSSKTFAQ
                     LIGDEFLVKKLTEEWQEDVKKYL"
     gene            complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ865_001811"
     CDS             complement(4187..4747)
                     /gene="rnmV"
                     /locus_tag="VQ865_001811"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000660004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HET3136114.1"
                     /translation="MKEKISQVIVVEGRDDTVNLKRYFDVETYETRGSAINDQDIERI
                     QRLHQRHGVIVFTDPDFNGERIRRMIMTVIPTVQHAFLKRDEAVPKSKTKGRSLGIEH
                     ASYEDLKTALAQVTEQFEHESQFDISRSDLIRLGFLAGADSRKRREYLGETLRIGYSN
                     GKQLLKRLELFGVTLAEVEEAMKSYE"
     gene            complement(4747..5520)
                     /locus_tag="VQ865_001812"
     CDS             complement(4747..5520)
                     /locus_tag="VQ865_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000575597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HET3136115.1"
                     /translation="MIFDTHTHLNVEEFAGREAEEIALAAEMGVTQMNIVGFDKPTIE
                     HALELVDEYEQLYATIGWHPTEAGTYTEEVEAYLLDKLKHSKVVALGEIGLDYHWMTA
                     PKEVQEQVFRRQIQLSKNLDLPFVVHTRDALEDTYEIIKSEGVGPRGGIMHSFSGTLE
                     WAEKFVDLGMTISFSGVVTFKKATDLQEAAKELPLDKMLVETDAPYLAPVPKRGRENK
                     TAYTRYVVDFIADLRGMTTEELAAATTANAERIFGLDSK"
     gene            complement(5825..6718)
                     /locus_tag="VQ865_001813"
     CDS             complement(5825..6718)
                     /locus_tag="VQ865_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001816585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1542 domain-containing protein"
                     /protein_id="HET3136116.1"
                     /translation="MVAQDPKAQDSTKPTAEKSTVKAPAQRVDVKDITHLTDEEKVKV
                     AILQANGSALDGATINVAGDGTATITFPDGSVVTILGKDTVQQSAKGESVTQEATPEY
                     KLETTPGGDKGGNTGRSDANANAGGGSQAGGPVHTGSQNSAQSQASKQLATEKESAKN
                     AIEKAAKNKQDEIKGAPLSDKEKAELLARVEAEKQAALKEIENAKTMEDVKEAETIGV
                     QAIAMVAVPKRPVAPNAAPKTTSAPQATAGTMQDVTYQSPAGKQLPNTGSASSAALAS
                     LGLVVATSGFALLGRKTRRRK"
     gene            complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ865_001814"
     CDS             complement(7002..7136)
                     /gene="rpmH"
                     /locus_tag="VQ865_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000831903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HET3136117.1"
                     /translation="MKRTYQPSKLRRARKHGFRNRMSTKNGRRVLAARRRKGRKVLAA
                     "
     gene            complement(7281..8495)
                     /locus_tag="VQ865_001815"
     CDS             complement(7281..8495)
                     /locus_tag="VQ865_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3136118.1"
                     /translation="MKEYNKSSKLEHVAYDIRGPVLEEAMRMRANGEKILRLNTGNPA
                     EFGFTAPDEVIHDLIMNARDSEGYSDSKGIFSARKAIMQYCQLKKFPNVDIDDIYLGN
                     GVSELIVMSMQGLLDNGDEVLVPMPDYPLWTAAVSLAGGNAVHYICDEAVEWYPDIDD
                     IKSKITSNTKAIVLINPNNPTGALYPKELLLGIIEIARQNDLIIFADEIYDRMVMDGH
                     VHTPVASLAPDVFCVSMNGLSKSHRIAGFRVGWMVLSGPKTHVKGYIEGLNMLSNMRL
                     CSNVLAQQVVQTSLGGHQSVDELLLPGGRIYEQRNFIYNAIQDIPGLSAVKPKAGLYI
                     FPKIDRNMYRIDDDEQFVLDFLKQEKVLLVHGRGFNWQEPDHFRIVYLPRVDELAQIQ
                     EKMTRFLKQYRR"
     gene            complement(8651..8944)
                     /locus_tag="VQ865_001816"
     CDS             complement(8651..8944)
                     /locus_tag="VQ865_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009014348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136119.1"
                     /translation="MMKNSFQKSNFLYYGIILVSVLVEVIMIWQLESLVPLIYPGFIG
                     FLVFHVLYHLILFLVAKRSGRWDYLMIWGLFLMFNLLYDSFLGLLFLGLSFGM"
     gene            9106..9558
                     /locus_tag="VQ865_001817"
     CDS             9106..9558
                     /locus_tag="VQ865_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HET3136120.1"
                     /translation="MAQRYQNIMVAIDGSKEADLAFVKGVHSALRNDAKLTIVHVIDT
                     RALQSVSTFDAEVYEELQVDAESLMKEYEKRAKDAGVADVHIVIEMGNPKTLLARTIP
                     DAEEVDLILVGATGLNAFERLLVGSSSEYILRHAKVDLLVVREQEKTL"
     gene            complement(9593..10981)
                     /locus_tag="VQ865_001818"
     CDS             complement(9593..10981)
                     /locus_tag="VQ865_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HET3136121.1"
                     /translation="MEVKAVFFDIDGTLVNNRKSVLKSTKDAIKIVKEQGVLVGVATG
                     RGPFFVKELMDDLDLDFAVTYNGQYIFSKDRVLFTSPISKLHLRHLISYAKKEGTEIA
                     LGTKDAMLGSKIMSFGLGSFSQRISRFVPSVLTRTVSQSFNRMVSKVVPQKEEDLLHL
                     MNQPIYQVLMLMTPEESEKAAADFEDLKLTRSNPFASDVINQGNSKLEGIRRVGKEYG
                     FDLNQVMAFGDSDNDLEMLAGVGMSVAMGNGSSSVKEAAKHITTSNQQDGIHKALEHF
                     GVLSSEKVFVSRDYHFNKVKTFHHMMDERTQEEPRAWDLEGATHRAGFKIEELVEFVR
                     AASPSEEDFGQAVSQLHQALDKAAGKVAKKTPAQQDLIGQVDALIDTLYFTYGSFVLM
                     GVDPERIFDIVHQANMGKIFPDGKAHFDPVTHKILKPDNWEEKYAPEPAIKKELQRQL
                     KAYERHKERNKS"
     gene            11047..12009
                     /locus_tag="VQ865_001819"
     CDS             11047..12009
                     /locus_tag="VQ865_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007522433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HET3136122.1"
                     /translation="MPKKILVLHTGGTISMQADASGAVVTSSDNPMNHVSNPLEGIQV
                     HALDFFNLPSPHIKPKHMLVLYQKIKEEADNYDGVVITHGTDTLEETAYFLDTMEVPH
                     MPIVLTGAMRSSNELGSDGVYNYLSALRVASDDRAADKGVLVVMNDEIHAAKYVTKTH
                     TTNVSTFQTPTHGPLGLIMKQEILYFKTAEPRVRFDLDHIQGLVPIISAYAGMTDELI
                     DMLDLEHLDGLIIQAFGAGNIPKETAQKLESLLQKGIPVALVSRCFNGIAEPVYAYQG
                     GGVQLQKAGVFFVKELNAQKARLKLLIALNAGLTGQALKDYMEG"
BASE COUNT         3435 a         2823 c         2193 g         3576 t
ORIGIN      
        1 aaaaaaatca gcttcttgat aacttcgatt ttcgggtagg gtcaaatcca catcctcctc
       61 cacatcatcc actgtcagtt caaccgtttg aggtaaattt ttcaaacgat aatgcttttg
      121 cctttgccct tcactactag caaaatcaag caaatagcca tgcactcgga tttgaaccaa
      181 aaggagatga ttggtcatat tttccatgat gaggatatct tataaaccac ctctggcact
      241 aggataatca gataccctgc gaatacggat tttttcacac atgagcaagt ttcctcatat
      301 caatgatttc atcagcctta ttccagacta ggggattatg ggtcgcaatg atgataattc
      361 gattttcatc tttcaaatcc accaagagat tcataacctc ctctgaattt tcaggatcaa
      421 gagctgctgt tggttcatct gccaaaatca agggtggatt tttcaaaata gttttcgcaa
      481 gggcaactcg ttgggcctct cccccagata aagtataaat tttttgttct aaatccaaat
      541 accctagatt aactttttct aaagccccca cttgcctttc caaacgttct acttttgaga
      601 ttttctgacc aacaaaaccc aaatccaaat tttctttgat tgattggttt tctaagaggc
      661 caaaattttg aaagagatag cccatctgat ctcgaaaata ctcacgagtg ggaatggttt
      721 ttaaatcttt cccctgatag agaacccttc ctccatctat cttttctagc tttcccaaga
      781 tattcagcag cgtcgtcttt ccgcttccac tctttccgat taaggcataa accttgccct
      841 tctccagctt gagattcaaa ccagagaaaa tcgcgcggtc attaaatttc ttttccaatc
      901 cttgaatatc aatcatctta ttttcctttc aatactgcca tgctaccagc ttcttctttt
      961 ttgtcctgcc ttactaaaat caagagggcg ttaagcgtaa acaaagctac aactagagcg
     1021 ctaatcaaac catctcttgt caaaatacta gataggacta ggccaagcaa gagaactcct
     1081 ccttgcgcca gtaaatactt gccatgaagc tcatagattg tcataccagc aagacgttta
     1141 atcataagct cccgtctgaa ctgctcaaaa tagagaagat tcatggaatc aaataacaag
     1201 atagccgtag acagggtcaa aatcgtccca ataaggagag agtaaaactc tacccgtttg
     1261 tcatttagta ccttggcaaa aatagctggc tttttaccaa gtaagaaacc ttgtgataca
     1321 gaccttgctc ttttagagct gtgatgctgt ctccatatcg atctagtttc aaggcactat
     1381 tagccgtagt tccccacaac atccctgcaa caggtcttgt tccagtcgct tgcggcgtta
     1441 gaactacaat aatcggatct tttaggtact ggcgtgttgt cttgtaccca tcattataga
     1501 ggaaacgttc ctgtcctgtt tctgtaaaag ctagacttac ctgtgggagg tagtatttct
     1561 gactcgtcac ttctacactt tcagatgaaa agttttgcag gtaatctgta aacaatcctt
     1621 ggtagtaggc agactgctct cgcaagctct caggcaagat cagcccaaac tctccctcag
     1681 acaagttttg catcttgtcc ataaactctg aagaaacggt aatcttttct tctatcagat
     1741 agcgtggtga gacatagata acattccctg acggtgtgta gtcactgaga cgattgccat
     1801 ctaggtccac ttctgctccg tctgagaaat tgtcaacatt gctcataata taaaaagagt
     1861 ctgtattggc taaccgttct tcagtaaatg tctgccactc acgattatcc ttacgcgttc
     1921 cttcttcatc ggcaaatgca ctagaccaac caaaggatag acggtaacgg tctgaggact
     1981 ggctccattt attgctagct ctctccattt cctgcatttc acggtagtgg ggtaggagag
     2041 ctgtcgcact cgatccgacc accaatacag ctaagagttg ccccaccatc atcaatgtca
     2101 tcatacgttt gagagggagt ttccctttca atagatccac cagactattt tcctgtaaac
     2161 caagtagata gacgacactt agtaaggtag aaatccctgc cagggtcaat ccataaagta
     2221 gaagagcaat gatgaccagt tgcaccgttg ccataaacaa gacaccttga taccagagaa
     2281 tccccaatcc caaaagactg gataccagca ctgagtagat aaactgtctc acatcttcta
     2341 acactggtct gagagcaact ccaaacaagc tctcaccagc tattaagcga atccctgcct
     2401 gacgaaggga tttgatccga taaatcaggg tcagactcat aaaggtcagc agaaaaatag
     2461 ctaaactcag tagcaccata ggggtggccg ccaatagtaa gactatcgaa aatggatctt
     2521 ctccattcga aacaaagcct tgatagccaa gttctttcaa ggtggtctgt aagctcactc
     2581 catccaaact tcctgacaca atcaagtaag accctaataa atcactcgtt tctgcactct
     2641 ccttggagga aatggtcaga ccttctggaa gctctccctc accataagtg gcataggtaa
     2701 agagtgtttc tccagcttca tttggctcaa cgattcgacg ggcgatgaga ctattatgct
     2761 ctaccgccaa gtgactcaaa acctctgtca cctcttcgcg actagctact ggttgattta
     2821 tcatcattcc tgtcacatca acagaaggat agttaccaaa taaaatctct tctcgatggt
     2881 caacggaagt tatcaccata taaagcgata ccaataccat tgaaatcaaa ataaataaac
     2941 gtttcatcat ttcctccaaa aagttacttg gtcacttagt gagaaggtga ccacagtcac
     3001 tgcgatgtta agaagcttat taagttcttt ctactagcaa catcttcaaa tacattatat
     3061 ccgttttttc aagaactatc aaggacatca atgtccttaa aatctaacca tttcgtgtca
     3121 tttttagctt atatctaaaa aaacagccct aaagacgaac tttagaactg ttttgatgcg
     3181 agaacaagga catttttgtc actgattcac tatgtttata aatatttttt gacatcctct
     3241 tgccattcct ctgtcaattt ctttactaga aattcatctc caattagctg cgcaaatgtt
     3301 ttagaagact gataaaatga ttcagctaaa ctaaaatctc tttcttctct taatgcttgc
     3361 ttccacaaaa acataaatac aagaggtttc ttttgataat cttgagtttt atccataatt
     3421 tcttgtaaac acgatagata atcattaaaa caatcagtta ctcctacctt ttcaagacaa
     3481 cacattcctg aaataagagt atctctaatt ataaagaagt tttctaattt agttaccttt
     3541 ttctgttcca aaagaaagag cattagcttt tcgatttgat ttataaattt ggcaagatct
     3601 tttctaatga gcatttgata aaaaaacaaa cgaatcaaca acatatcatt tgttgaataa
     3661 acttcttttt ctatgatctg aggcatatgt tcctcaagta ttaactctgc atattcaggc
     3721 cttctagttc tagaagtatc caaacacgcc tgcaatactt cacatgctaa ttgttcttct
     3781 ttaggaagat tatcaaagta tgttttataa atctcttcca aacacgcttc cttcttatcg
     3841 tactcctctt ctttaccata gattggttca cgtaaaatct ggtatttcaa ttctaaataa
     3901 gcaggaggaa gagctgaaaa atccggcata aggctataaa ctggaactcc tagccggcga
     3961 gcaatatagt ctaacttggg caaactcggt tgcgaagctc cactttcaat tcgcgacagt
     4021 tgacgaactg tcagttcttg ctcatctcca caaaaatctg gacgactaat tcctttttct
     4081 atccgaatct ctttaatttt ttgaccaatt aacatcagac gcctcctctt ctacctgctt
     4141 cgaaaaatac tgtgaaactt aaaaaattgt aacggctaca tctttcctac tcataagatt
     4201 tcatagcttc ttccacttct gccaaagtaa ccccaaacaa ctctaggcgt ttgaggagtt
     4261 gcttgccgtt ggaatagccg attcggagag tctctccgag atattctcta cgcttacggc
     4321 tgtctgcccc tgctagaaaa ccaaggcgaa tcaaatcgct acgactaatg tcaaactgac
     4381 tctcatgttc aaattgttct gtcacctgag ctagagccgt tttcaggtct tcatagctgg
     4441 catgctcaat tcccagagaa cgccccttgg tcttggactt gggaacagct tcatctcgct
     4501 tgagaaaggc atgctgaact gttggaatga ccgtcatgat catgcgccga atccgttccc
     4561 cattaaaatc tgggtctgta aagacaatga ctccatgacg ttggtgcagg cgctgaatcc
     4621 gctctatatc ctgatcattg atggcagaac ctcgagtctc ataggtctcc acatcgaaat
     4681 aacgcttgag attgaccgta tcatcacgcc cttcaaccac aattacttgg gaaattttct
     4741 ctttcattac ttgctgtcca atccaaaaat gcgttctgca tttgcagtcg ttgccgccgc
     4801 tagctcttct gtcgtcatac cacgcaagtc agcgataaag tcgaccacat agcgagtata
     4861 ggctgtttta ttttcacggc cacgcttggg tacaggtgct aagtaaggcg catctgtttc
     4921 caccaacatc ttgtccaaag gtaactcttt agctgcttct tggaggtcag ttgccttctt
     4981 gaaagtcacc actcctgaga aggaaatggt cataccaaga tccacaaact tctctgccca
     5041 ctcaagcgtc cctgaaaatg aatgcatgat accaccacga ggaccaacgc cctcactctt
     5101 gataatctca taggtatctt ccagcgcatc acgggtatgg acaacaaaag gcaaatccaa
     5161 gttcttagat agctgaatct gacggcgaaa aacctgctcc tgcacctctt tgggcgctgt
     5221 catccaatgg tagtctaagc caatttcacc taaagccaca accttggaat gttttaactt
     5281 atccaacaag taagcctcaa cttcctctgt ataagtacca gcttctgtag gatgccaacc
     5341 aatagtcgca tagagctgct catactcatc taccaactcc aaggcatgct caatcgtcgg
     5401 tttatcaaaa ccaacaatat tcatctgtgt cacacccatc tcagcagcca aggcaatttc
     5461 ttctgcctca cgacctgcaa attcttctac attcaagtgt gtatgtgtat caaaaatcat
     5521 ctcttctaac ctcgttttct atcttctatt ataccaaaaa agaggagggg cacctaattt
     5581 ttcggtttcc cctcctctct tcaataaaga gctattctgc tatcttttct atccgatatt
     5641 gcccatctcc tattccacag ttagagacag aagagattgg ctacattgat agaatattcc
     5701 tattcagcta aagtatgtga ttatcttggg ttctcacttt tctcacccat cactaggatt
     5761 gatgacttct caaaatcccc cttataatct aactttaagt agagaataga attttctagc
     5821 tgttctattt tctacgtcta gtctttcttc ctagcaaagc aaaaccactt gttgccacca
     5881 ctagaccaag actagcaagt gctgcacttg atgctgaacc tgtgttaggt aattgtttgc
     5941 cagcaggtga ctggtaggta acatcttgca ttgttcctgc agttgcttgc ggtgcacttg
     6001 ttgtcttagg agcagcatta ggagccactg gtctcttagg aactgcaacc atggcaatgg
     6061 cttgcactcc aatcgtttct gcttccttca catcttccat agttttcgca ttttcaatct
     6121 ctttgagagc tgcttgtttt tctgcttcca ctcttgctaa aagttctgct ttttctttat
     6181 cagaaagcgg tgcgcctttg atttcatcct gcttgttctt ggctgctttt tcaatggcat
     6241 ttttagctga ttctttttca gtagctaatt gcttagaagc ttgtgattga gctgagtttt
     6301 gtgaacctgt gtgaactggt ccacctgcct ggctaccacc gcctgcattc gcattagcat
     6361 ctgatcttcc agtattgcct cccttatctc cacctggtgt agtttctagc ttatactctg
     6421 gtgtagcttc ttgagttaca gattcacctt tcgcagattg ttgaactgta tcttttccta
     6481 gaatcgtcac tactgaacca tctgggaatg tgattgttgc tgtaccatct ccagctacat
     6541 tgattgtcgc tccgtctaat gctgaaccat ttgcttgtaa aatagcaacc ttaacttttt
     6601 cttcatctgt taaatgagtt atatctttta catctactct ttgagcaggt gctttaacag
     6661 ttgatttttc agcagtcggt ttagtactat cttgtgcttt tggatcttgt gctaccaatt
     6721 gatttcctgg aattgtaata gctgaaccat ctttaaagac gattgtcgct gtaccatctc
     6781 cagctacttc aactttatag taaaataaaa taataacagg acaaatcgat caggacagtc
     6841 aaatcgattt ctaacaatgt tttagaaaca gaggtgtact attctagttt caatctacta
     6901 taacatcgct tccgaatcca tttgcatcta ctgaactttt ttacaaaaat aaaaatcagt
     6961 agactcgagt tcctactgat ttttgataga attcgtttgg attatgcagc caaaactttg
     7021 cgtcctttac gacgacgagc tgccaatacg cgacgaccat ttttagttga catacggtta
     7081 cggaatccgt gtttgcgcgc acgacgaagt ttacttggtt gataagtacg tttcacgatg
     7141 aatacctcct catagatttt gtattcgttt agccggctat aaagtgatca gttactaaac
     7201 atactttact attctatctg attctttcac ttttgtcaat agctctaggc aaatgtttcc
     7261 agctttttcg aatgcaagcc ctatctacga tactgtttca agaaacgagt catcttttct
     7321 tggatttggg ctaactcatc aacacgagga aggtaaacga tacggaagtg gtctggttcc
     7381 tgccagttaa agcctcgacc atgaaccaag agaacctttt cctgcttcaa gaaatcaagg
     7441 acaaactgct catcatcatc gatacggtac atattgcggt cgatttttgg gaagatatag
     7501 agccccgcct tgggtttaac ggcagacaaa cctggaatat cttgaatggc attatagatg
     7561 aaatttcttt gctcgtagat tcgtccacca ggaagaagca attcatcgac tgattggtga
     7621 ccccccaagg aagtttgtac gacttgttgg gccaaaacgt tagagcaaag gcgcatattg
     7681 gacagcatat tgagcccttc gatatagccc ttaacatgag tcttagggcc agacaagacc
     7741 atccaaccca cacggaaacc tgctatgcgg tgggattttg acagaccatt catgctgaca
     7801 cagaagacat ctggtgccaa gctcgccaca ggcgtatgca catgtccgtc cattaccatg
     7861 cggtcataga tttcatccgc aaagataatc aaatcgtttt gacgggcaat ctcaataatc
     7921 cccagcaaga gttccttagg ataaagggct ccagttgggt tatttggatt gataaggaca
     7981 attgccttgg tattggaagt gatttttgac ttgatatcgt caatatctgg gtaccattcc
     8041 acagcttcat cacagatata gtgaacggca tttcctccag ctaggctgac agccgccgtc
     8101 catagaggat agtctggcat tggcactaag acctcatccc cattgtccaa aagcccctgc
     8161 atggacatga caatcaactc actgacacca tttccaaggt aaatatcatc aatatctacg
     8221 tttgggaatt tcttcagctg gcaatactgc atgatggcct tacgggctga gaaaatccct
     8281 ttggagtcag aatagccttc actatcacgc gcattcataa tcaagtcatg aatgacctcg
     8341 tctggcgctg taaagccaaa ttctgctgga tttcctgtat tcagacgtaa aatcttttct
     8401 ccattcgctc gcatccgcat ggcttcttcc aatacaggac cacggatatc ataagcaaca
     8461 tgctctaact tactagactt gttatattct ttcatcttgt ttcctcaatt catcaggata
     8521 gtaacattat accactagaa agagaatgcg acaagtttac tgaaatgtgt tactagtttc
     8581 gtatagaaga aaaaccttgc taaaggcgag gttaagaacg tagagatagc aggtattttg
     8641 caaagacaca tcacatacca aaagataaac ctagaaaaag caagcctaga aaggagtcat
     8701 aaagaagatt aaacatgagg aaaagccccc atatcatcaa gtaatcccaa cgcccacttc
     8761 gttttgcaac tagaaataag attagatggt agagtacatg aaagactaaa aatccaataa
     8821 aacctggata aataagcggt accaaactct ctaattgcca gatcatgatc acttctacca
     8881 agactgaaac taggataatt ccataataca ggaaatttga tttttgaaaa gagtttttca
     8941 tcattctccc ttccttcact tctttcctgc tatcctttct tttattttat catatattta
     9001 tatagatttt aagccctaat attcttttga aaaatacttt ttttgcttta cttctatagt
     9061 gaaaaggttt acaattatag taagaaaatt tcaggaggtt tcattatggc acaacgttac
     9121 caaaatatca tggtcgcaat cgatggttct aaggaagcgg acttggcttt tgtcaaggga
     9181 gttcattctg ctctacgaaa cgacgctaaa ctcaccatcg tacatgtcat tgacacacgc
     9241 gctctccaaa gcgtatccac ctttgatgct gaagtttacg aagaactcca agtcgacgct
     9301 gaaagtctga tgaaagagta cgaaaaacgt gctaaagatg ctggggtagc agatgttcat
     9361 atcgtcattg aaatgggaaa tccaaagacc ctgctagcac gtactattcc agatgccgag
     9421 gaagtggacc tcatcctcgt tggcgcaact ggtctcaacg cctttgaacg cctcttagtc
     9481 ggctcttcat ctgaatacat actccgccat gctaaggtcg atttgctggt tgtgagagaa
     9541 caagaaaaaa ccttataatc acaaagaaaa ggagccccta gctccttttt gtttacgatt
     9601 tatttctctc tttatggcgt tcgtaagcct tgagctggcg ctgcagttcc tttttaatag
     9661 caggttctgg agcatatttt tcttcccaat tatctggttt taagatttta tgggtcactg
     9721 gatcaaaatg agccttgcca tctggaaaaa ttttccccat attggcctga tggacaatat
     9781 caaaaatacg ttctgggtcc acccccatca agacaaaact gccgtaggtg aagtaaagcg
     9841 tgtcaatcaa ggcatccact tgccctatca aatcttgctg agcaggtgtc ttcttggcta
     9901 ctttacctgc tgccttatca agggcctgat gaagttgcga tacagcttga ccaaaatctt
     9961 cttcagaagg actggctgct cgaacaaact ccaccaattc ttctatttta aaaccagccc
    10021 tatgggttgc accctctaaa tcccaagctc gaggttcttc ttgggttcgt tcatccatca
    10081 tgtggtggaa ggtcttgacc ttattgaaat gatagtcacg gctgacaaag actttttctg
    10141 aagacaaaac accaaaatgt tccaaggcct tgtggatccc atcttgttga ttgctagtgg
    10201 taatgtgctt ggcagcttcc ttgacactgc tactaccatt tcccatagcg accgacatac
    10261 cgacgccagc cagcatttca aggtcattat ctgagtcacc aaaagccatg acttggttga
    10321 ggtcaaagcc atattctttc ccaactcggc gaatgccttc taatttagaa tttccctgat
    10381 tgatgacatc cgatgcaaaa ggattgctac gtgtcaattt caagtcttca aaatcagctg
    10441 ccgccttctc agattcttct ggtgtcatca gcatcaaaac ttggtagata ggctgattca
    10501 tcaggtgaag caggtcctct tccttttggg gaacaacctt gctgaccatg cgattaaaag
    10561 actgactcac cgtccgagtt aaaacagagg gaacgaagcg actaattcgt tgggaaaaag
    10621 aacccagacc aaaggacatg attttagaac ccaacatggc atccttggtc cctagagcaa
    10681 tctccgtgcc ctctttttta gcatagctaa ttagatggcg caaatgtaac ttggaaatag
    10741 ggctcgtgaa caagactctg tctttactaa agatatactg gccattatag gttaccgcaa
    10801 aatccagatc caaatcgtcc atcaattcct taacaaaaaa aggtcctcgt cctgtcgcta
    10861 cgccaactag taccccttgt tctttgacaa tcttaatcgc gtccttagtg gatttcaaaa
    10921 cactcttgcg attgttgacc aaggttccat cgatatcaaa aaaaacagct ttgacttcca
    10981 tcctattcca atctcccctt ttgtgataca atgattatac cacatttcag aaagagttag
    11041 taaatcatgc ctaagaaaat ccttgtttta catacgggtg gaactatttc catgcaggcc
    11101 gatgcttctg gcgctgttgt gacgagttca gataatccca tgaaccatgt gtccaaccca
    11161 cttgaaggaa tccaagtcca cgccttggac ttttttaacc ttccaagtcc ccatatcaaa
    11221 cccaaacata tgctggtcct ctaccagaaa attaaagagg aagcagataa ctacgatgga
    11281 gtggtgatca cacacggaac cgatacttta gaggaaacag cctatttcct tgataccatg
    11341 gaagttcccc atatgcctat cgttctaaca ggagccatgc gtagctccaa tgagctcggt
    11401 agtgatggtg tttataatta cctaagtgct ttacgagtgg ccagcgatga cagggctgct
    11461 gacaaaggag ttttggtcgt tatgaacgat gaaatccacg ctgccaagta tgtcaccaaa
    11521 acacatacga ctaatgtcag caccttccag actccaacac atggccccct cggtctcatc
    11581 atgaaacagg aaatcctcta cttcaaaaca gctgaacctc gtgttcgctt tgaccttgat
    11641 cacatacaag gtttagtccc tatcatctcg gcttatgctg gtatgacaga tgagctgatt
    11701 gatatgctgg atttagaaca cttggacggt ttgattatcc aagccttcgg agctggtaat
    11761 attcccaaag aaacggctca aaaattagaa agccttctgc aaaaaggaat cccagtcgct
    11821 ctggtatcac gatgctttaa cggtattgcc gagcctgttt atgcctacca gggtgggggc
    11881 gtacagttgc aaaaagcagg cgttttcttt gttaaagaac tcaacgccca aaaagctcgc
    11941 ttgaaactcc tcatcgccct caatgccgga ctaacaggac aggctttgaa agactatatg
    12001 gaaggctaat actcttcgaa aatctct
//
LOCUS       DAVBOG010000057        11716 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.057, whole genome shotgun sequence.
ACCESSION   DAVBOG010000057 DAVBOG010000000
VERSION     DAVBOG010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11716)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11716)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11716
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.057"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ865_001820"
     CDS             complement(122..604)
                     /gene="greA"
                     /locus_tag="VQ865_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018370745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HET3136123.1"
                     /translation="MAEKTYPMTLEEKEKLEKELEELKLVRRPEVVERIKIARSYGDL
                     SENSEYEAAKDEQAFVEGQISSLETKIRYAEIVNSDAVAQDEVAIGKTVTIQEIGEDE
                     EEVYIIVGSAGADAFAGKVSNESPIGQALIGKKTGDTATIETPVGSYDVKILKVEKTA
                     "
     gene            complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ865_001821"
     CDS             complement(675..2330)
                     /gene="mltG"
                     /locus_tag="VQ865_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HET3136124.1"
                     /translation="MSEKSREEEKLSFKEQILRDLEKVKGYDEVLKEDEAVVRTPANE
                     PSAEELMADSLSTVEEIMRKAPTVPTHPSQGVPASPADEIQRETPGVPSHPSQDVPSS
                     PAEESGSRPGPGPVRPKKLEREYNETPTRVAVSYTTAEKKAEQAGPETPTPATETVDI
                     ISDTSRRSRREGAKPVKPKKEKKSHVKAFVISFLVFLALLSAGGYFGYQYVLDSLLPI
                     DANSKKYVTVGIPEGSNVQEIGTTLEKAGLVKHGLIFSFYAKYKNYTDLKAGYYNLQK
                     SMSTEDLLKELQKGGTDEPQEPVLATLTIPEGYTLDQIAQTVGQLQGDFKESLTAEAF
                     LAKVQDETFISQAVAKYPTLLESLPVKDSGARYRLEGYLFPATYSIKESTTIESLIDE
                     MLAAMDKNLSPYYSTIKSKNLTINELLTIASLVEKEGAKTEDRKLIAGVFYNRLNRDM
                     PLQSNIAILYAQGKLGQNISLAEDVAIDTDIDSPYNVYKNVGLMPGPVDSPSLDAIES
                     SINQTKSDNLYFVADVTEGKVYYANNQEDHDRNVAEHVNSKLN"
     gene            complement(2411..2905)
                     /locus_tag="VQ865_001822"
     CDS             complement(2411..2905)
                     /locus_tag="VQ865_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000702438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136125.1"
                     /translation="MKIRQARLEDLDRIVELEFENFSVEEAIPPSVFEAHLREIQTSF
                     LVAEKEGRIMGYIEGPVGLHRHLQDQSFTEEIKDYSHEPGGYISVTCLSIAKEAQGLG
                     LGQKLLTALKEVALEDERDGINLTCHDYLIAYYEKHGFVNEGQSQSTFAGETWYDMVW
                     EMKK"
     gene            complement(2902..3366)
                     /locus_tag="VQ865_001823"
     CDS             complement(2902..3366)
                     /locus_tag="VQ865_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136126.1"
                     /translation="MEIPIKIIQASKSDLPEIGALQTSSFPAEKQQLSHILEESIRKC
                     ADTFLLARDENQLLGYILSSPQSDNPQYLKVHSLVIESDHQRQGLGTLLLAALKEVAV
                     DLDYKGIRLESPDELLSYFEMNGFVDEEATLLYATSQGYSMIWFNPFYLEEQ"
     gene            complement(3376..4710)
                     /locus_tag="VQ865_001824"
     CDS             complement(3376..4710)
                     /locus_tag="VQ865_001824"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HET3136127.1"
                     /translation="MSKTYHFIGIKGSGMSALALMLHQMGHKVQGSDVEKYYFTQRGL
                     EQAGITILPFDEKNLDGDMEIIAGNAFRPDNNVEIAYADQNGISYKRYHEFLGSFMRD
                     FVSMGVAGAHGKTSTTGMLSHVLSHITDTSFLIGDGTGRGSANAKYFVFESDEYERHF
                     MPYHPEYSIITNIDFDHPDYFTSLEDVFNAFNDYAKQITKGLFVYGEDAELRKITSDA
                     PIYYYGFEAEGNDFVASDLIRSTTGSTFTVHFRGQNLGQFHIPTFGRHNIMNATAVIG
                     LLYTAGFDLNLVREHLKTFSGVKRRFTEKIVNDTVIIDDFAHHPTEIIATLDAARQKY
                     PSKEIVAVFQPHTFTRTIALLDDFAHALNQADAVYLAQIYGSAREVDHGDVKVEDLAN
                     KINKKHQVITVENVSPLLDHDNAVYVFMGAGDIQTYEYSFERLLSNLTSNVQ"
     gene            complement(4721..5338)
                     /locus_tag="VQ865_001825"
     CDS             complement(4721..5338)
                     /locus_tag="VQ865_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3136128.1"
                     /translation="MKQERFPLVSDDEVMLTEMPVMNLYDESDLISNIKGEYRDKNYL
                     EWAPIAEEKPVKPIEKQVGKPKKAPLGVKKEGKSYAEVAREEARADLKKKRSANYLTQ
                     DFSLARRHSQPSLVRQGNQPTTPFQKENPGEFVKYSQKLTQSHYILAEEVHSIPTKNE
                     EVSAPAPKKNNYDFLKKSQIYNKKSKQTEQERRVAQELNLTRMTE"
     gene            complement(5386..8484)
                     /locus_tag="VQ865_001826"
     CDS             complement(5386..8484)
                     /locus_tag="VQ865_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3136129.1"
                     /translation="MAKLIPGKIRIEGVALYETGKVDIIKEKNNRLYARVAEEELRYS
                     LEDDLVFCACDSFQKRGYCVHLAALEHFLKNDERGQEILWSLEEGHEEKEAVETKVTL
                     GGKFLNRILSPKSECAYELSAVGQVEAGTNHILWTLRIGQINSQKYYVIRDIPLFLRI
                     VEQRKSYMIGKIYEESLSWEAFDDASQELLTFLHGLTEEGLVPDLFFQNQGRHLFFPL
                     TFFEQGVNLLMALPHFQFDHQVDSYQTLLFQDMHADANLFAFTVTEYSDYFEMEISES
                     PRVNVFYQGAVLFHKGQVYFLTDQQMRLLKEIKALPVGQQGKKYLQFDSSDRDKLASC
                     LTLFIQMGTVSAPERLQIKTFAPSFYFDREEDNRIRLEIQFDYGNRQVSSRQELEELP
                     FSSDADLEERIFQVCLAAGFEADFQSWRQALKAESVYHFFHDIIPVFEKLGHVDLSDK
                     LEELYSLASPQVQIASKGGLLEIQFDFQNIAQEEIDQAMQALVANQDFYIDSSNQVYF
                     FDEETKKIRQNLQELGQFELKDGTLQARKSLAYSLAHLFEGRDRVSFSQEFQNLAQDL
                     THPEDFPLQATQVKADLRDYQEKGIGWLQMLHHYGFGGILADDMGLGKTLQTIAFLTS
                     QVTKESRVLILAPSGLIYNWADEFQKFAPQLDVAVVHGLKASREEILAESHQIYVTSY
                     ATFRQDSEFYQGMAFDFLFLDEAQVMKNAQTKIAQTLRQFVVPSVFALSGTPIENHLG
                     ELWSIFQIVMPGLLPSKKEFMKLPAERVAQFIKPFVMRRKKEEVLTELPDLIEVVYKN
                     ELEDQQKAIYLAQLQQMRDHLAQVSEQEFQRSRVEILSGLMRLRQICDTPALFMEDYQ
                     GASGKLDSLRDLLVQVADGGHRVLIFSQFKGMLEKIEQELSDLGLTSFKITGSTPAKE
                     RQDMTKAFNQGERDAFLISLKAGGVGLNLSGADTVILVDLWWNPAVEAQAIGRAHRMG
                     QEETVEVYRLVTKGTIEEKIQELQEQKKHLVSQVLDGTESRGSLTLAEIREILGISEA
                     ST"
     gene            complement(8577..9743)
                     /locus_tag="VQ865_001827"
     CDS             complement(8577..9743)
                     /locus_tag="VQ865_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HET3136130.1"
                     /translation="MGKYDFTSLPNRLGHHTYKWKETETDSEVLPAWIADMDFVVLPE
                     IRQAVQTYADQLVYGYTYASEDLIKEIQKWEATQYGYNFDKEALVFIEGVVPAISTAI
                     QTFTKEGEAVLINTPVYPPFARSVKLNNRRLITNSLVEKDGLFEIDFDQLEKDLVEEE
                     VKLYILCNPHNPGGRVWEKEVLEKIGQLCQKHGVLLVSDEIHQDLTLFGHKHQSFNTI
                     NPAFKNFAIVLSSATKTFNIAGTKNSYAVIENPKLRLAFQKRLLANNQHEISGLGYLA
                     TEAAYRYGKDWLEELKQVFEDHINYVVDLFGKETKIKVMKPQGTYLIWLDFSAYDLTD
                     ETLQELLRNEAKVILNRGLDFGEEGSLHARINIAMPKSLLQEVCQRIVATFAKR"
     gene            complement(9751..10845)
                     /locus_tag="VQ865_001828"
     CDS             complement(9751..10845)
                     /locus_tag="VQ865_001828"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HET3136131.1"
                     /translation="MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRST
                     GFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLY
                     GGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAK
                     LAHAKGAKVVVDNTFYSPIYQRPIEDGADIVLHSATKYLAGHNDVLAGVVVTNSLELY
                     EKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLY
                     TGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHS
                     YGLTDDLLRLSIGIEDARDLIADLRQALEG"
     gene            complement(11003..11656)
                     /locus_tag="VQ865_001829"
     CDS             complement(11003..11656)
                     /locus_tag="VQ865_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012386829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3136132.1"
                     /translation="MFKGQKIAFVGPSGSGKSTIVRLLERFYKPLSGDILMEQSSIYD
                     FNLKEWRSKIAWVSQNNAVLSGSIRDNLCLGLNRLVTDDELMKVLDLVSLGDEIRSMK
                     EGLDTEVGERGRLLSGGQSQRLQIARAYLKDAEILIFDEATANLDADSEYAIISSLYS
                     VLKEKTVVIIAHRLSTVKDVDCIFFLEEGKITGSGTHKELLENHERYARFVQEQMIE"
BASE COUNT         3252 a         2680 c         2220 g         3564 t
ORIGIN      
        1 aagtcagtaa ccatacatac ggcaaggcga cgctgacgtg gtttgaagag attttcgaag
       61 agtagcaaaa tggaaaaagg agtgagtgaa gcacatcgcc tccccactcc tttttctgtt
      121 tttaggctgt tttttcaacc ttcaagattt ttacatcata gctaccaaca ggcgtttcaa
      181 tggttgctgt atcacctgtt ttcttgccaa tcaaggcctg cccaattggg ctttcatttg
      241 aaaccttacc tgcaaaggca tccgcaccag ctgaacctac gataatataa acttcttctt
      301 cgtcctcacc aatttcttgg atggtgactg ttttaccaat cgctacttcg tcctgggcaa
      361 ctgcgtcgct attgacgatt tcagcatagc ggatttttgt ttctaagcta gagatttgtc
      421 cttcgacaaa ggcttgttca tccttagctg cttcgtactc actgttttct gaaagatcac
      481 cgtatgaacg ggcaatctta atgcgttcta ccacttctgg tcgacgaacc aatttcaatt
      541 cttctaattc tttttcaagt ttctcctttt cctcaagggt cataggatat gttttttctg
      601 ccatttttct caactttctt ctgataatat tttctaaaga aaattatgtg aagtatcaca
      661 taattttagt ttgtttagtt taatttgctg ttgacatgtt cagcgacatt gcggtcgtgg
      721 tcttcttgat tgttagcata gtagaccttg ccttctgtga catctgctac aaagtagagg
      781 ttatcgctct tagtttgatt gatgcttgac tcaatcgcat ccagacttgg actatcgact
      841 ggaccaggca tgagacctac atttttataa acattataag gtgaatcaat gtcggtatca
      901 atcgcaacat cctcagctag actgatattt tgccccagtt ttccttgggc atacaagatt
      961 gcaatattac tttgaagtgg catatcacga tttaaacgat tgtagaatac acctgcaatg
     1021 agcttacgat cttctgtctt ggcaccttct ttttcgacca aggaagcaat ggtcaacaac
     1081 tcattgatag tcaagttttt agatttgata gtactatagt aaggagatag gttcttatcc
     1141 atagcagcta acatctcatc aatcaagctc tcaatagttg tgctttcctt gatagagtat
     1201 gtagctggga aaaggtatcc ttccaaacga taacgcgcac cgctgtcttt tacaggcaaa
     1261 ctttccagta aagtaggata tttcgctact gcttgactga taaacgtctc atcttgaact
     1321 ttagccaaga aagcctccgc tgtcaaagac tctttgaagt caccttgcaa ttgacccaca
     1381 gtttgagcaa tctgatccaa ggtataacct tctggaattg tcaaagtcgc aagtacaggt
     1441 tcttgcggtt catctgttcc acctttttgc aactctttga gtaagtcttc tgtactcata
     1501 ctcttttgca aattgtagta acctgctttc aagtcggtat aatttttata cttggcataa
     1561 aaactaaaaa tcagaccatg ctttaccaaa ccagcttttt caagcgtcgt accgatttct
     1621 tgaacgtttg aaccttctgg aattccaacc gtcacatatt tcttagaatt agcatcgata
     1681 ggtaacaaag aatctagcac gtactggtaa ccaaagtaac cacctgctga gagcaaggca
     1741 aggaatacaa ggaatgaaat cacaaaagct ttcacatgtg acttcttctc tttcttaggt
     1801 ttaacgggtt ttgctccttc tctacggcta cgacgtgatg tatcgctgat gatatccact
     1861 gtttctgtag caggcgtagg tgtttctgga cctgcttgtt ctgctttttt ctctgccgtc
     1921 gtataggaaa cagctaccct tgttggggtt tcattgtatt ctctttcaag tttcttaggt
     1981 ctaacaggac ctggacctgg tcttgatcca ctttcttccg ctggagaaga aggtacatct
     2041 tgacttggat gacttggaac accaggagtt tctctttgaa tctcatctgc tggagaagct
     2101 ggtacacctt gacttgggtg agtaggcacg gtaggagctt ttctcataat ctcctctacc
     2161 gttgacaagg aatcagccat gagttcttca gctgaaggtt catttgcagg agtgcgaact
     2221 actgcctcat cttctttcag aacttcatca tagcctttta ctttttctaa atctctcaga
     2281 atctgctctt taaagcttaa tttctcttct tctcttgact tttcactcaa aagtttttcc
     2341 tccttgttga taatccataa tattatatct taaaagtcca aaaaaagcaa tctatgatac
     2401 ttttcctaac ttattttttc atttcccaga ccatatcata ccatgtttcc cctgcaaagg
     2461 ttgactggga ctggccttcg ttgacaaatc catgtttttc ataataggcg atgagatagt
     2521 catgacaggt tagattaatg ccatctctct catcttcaag agcaacttct ttcaaggctg
     2581 tcagcaattt ctgacccagt ccgagtccct gtgcctcctt ggcaatagac agacaggtca
     2641 cagagatata accaccaggc tcatgactat agtcttttat ttcttctgta aaagactggt
     2701 cttgcagatg gcggtgcagg ccaactggtc cttcgatata acccatgatt cttccttctt
     2761 tttcagcaac cagaaaagag gtctgaattt ctctcaaatg tgcttcaaag acagaaggag
     2821 gaatggcttc ttcgaccgaa aaattttcaa attcaagttc aacaatccga tccaaatctt
     2881 ctaatcttgc ttgtctgatt ttcattgttc ctccagataa aagggattaa accaaatcat
     2941 actatagccc tggctagttg catagagcaa agttgcttct tcatcaacaa aaccgttcat
     3001 ttcaaaatag gaaagcagct catcaggact ctccaaacga atccctttgt aatccagatc
     3061 aactgccacc tctttcaagg ctgcaagaag aagtgttccc aagccctgtc tctgatggtc
     3121 agactcgatg actaaagaat gtacttttag atattgcgga ttgtctgact ggggacttga
     3181 taaaatatag cctaaaagtt gattttcatc cctagctaga agaaaggtat ccgcacactt
     3241 acggatactt tcttctaaaa tatgggaaag ttgctgcttt tcagctggaa aagacgaggt
     3301 ctgaagtgcc cctatctcag gcaaatcaga cttgcttgcc tgaatgatct taattggaat
     3361 ttccatggga acatcctatt gaacattgct tgtcaagtta gacaagagac gctcaaatga
     3421 gtattcatag gtttggatgt ctcctgctcc cataaagacg taaacagcat tgtcatggtc
     3481 taggagcgga gaaacatttt caacagtaat cacttggtgt tttttgttga ttttgttggc
     3541 taggtcttct accttaacgt caccatgatc tacttcacga gccgagccat aaatttgcgc
     3601 tagataaaca gcatctgctt ggtttaaagc atgggcaaag tcgtccaaca aggcaatggt
     3661 tcttgtaaag gtatgcggtt gaaagactgc tacaatttcc ttgcttgggt atttctgacg
     3721 agccgcatcc aaggtcgcaa taatttctgt tggatgatgg gcaaagtcat cgataatcac
     3781 tgtatcattg acaattttct cagtgaaacg acgtttaaca ccggaaaatg ttttcaagtg
     3841 ctcacgcacc aagttcaaat caaatcctgc tgtgtaaaga agaccaataa cggctgtcgc
     3901 attcatgata ttgtgacgac caaaggttgg aatgtggaat tgccccaagt tttgtccacg
     3961 gaaatgaacg gtgaaggttg aaccagttgt tgaacgaata agatcactag ctacaaagtc
     4021 attgccttca gcttcaaaac cataataata aattggtgca tcagacgtaa tcttacgcaa
     4081 ttcagcatct tcaccataga caaaaagacc cttggtgatt tgtttggcat agtcgttaaa
     4141 ggcattgaaa acatcctcga gacttgtgaa ataatctgga tggtcaaagt caatgttggt
     4201 gataatagag tattctgggt ggtaaggcat gaagtgacgc tcatattcgt cagattcaaa
     4261 gacaaaatat ttggcattgg ccgaaccacg acctgtccca tctccaatca agaagctggt
     4321 atctgtaatg tgagacaaga catgagacaa catacctgtc gttgaagttt ttccatgtgc
     4381 tcctgctact cccatgctaa caaagtcacg cataaagcta cctagaaact catggtaacg
     4441 tttatagctg ataccatttt ggtccgcata ggcaatttcg acgttgttat ctggacgaaa
     4501 ggcatttcca gcgataattt ccatatcacc gtctagattc ttttcatcaa aaggaagaat
     4561 ggtaattcct gcctgctcaa gaccgcgttg ggtaaagtag tacttttcaa catctgatcc
     4621 ctgaaccttg tgccccatct ggtgcaacat caaggccaag gcactcatcc ctgatccctt
     4681 aattccgata aaatgatatg tctttgacat gttttctccc ctattctgtc attctggtca
     4741 gattcaactc ttgggcaacc cgacgttctt gttctgtttg tttacttttt ttattgtaga
     4801 tttggctctt ctttagaaaa tcataattgt ttttctttgg agcaggtgct gacacttctt
     4861 cattcttggt agggatagaa tgaacttctt ccgccaagat ataatgagac tgggtcaatt
     4921 tttggctata tttgacaaat tcaccaggat tttccttttg gaaaggagtt gtcggttgat
     4981 tgccctgtct aactagactg ggctgagaat gacgtctcgc aaggctgaaa tcctgagtta
     5041 gatagttagc agagcgtttc tttttcaagt ctgcacgcgc ttcttcacgc gccacctccg
     5101 catagctctt tccttctttt ttaaccccta aaggagcttt tttaggtttc cctacttgct
     5161 tttcaatcgg ttttactggt ttttcttcag caataggagc ccattctaaa taatttttat
     5221 ctcgatactc acccttgata ttactgatca gatcagactc atcatagaga ttcatgactg
     5281 gcatttcagt caacatgacc tcgtcatctg acaccaatgg aaatcgttct tgtttcattt
     5341 tctatttcct ttcaacactt cattatagcg tattgtcttg atttttcaag tgctggcttc
     5401 agaaattccc aaaatttctc taatttctgc tagggtcaga ctaccacgtg actctgtgcc
     5461 gtccaatact tgtgacacca gatgtttctt ttgttcttgg agttcctgaa ttttttcttc
     5521 aatggttccc ttggtcacca agcgatagac ctcaaccgtt tcttcctgac ccatccgatg
     5581 ggcacggcca atggcttgcg cttccaccgc aggattccac caaaggtcaa ccaagatcac
     5641 tgtatctgca cctgacaggt tcagaccgac cccaccagcc ttgagggaaa tcagaaaggc
     5701 atctctttct ccttgattaa aggccttggt catgtcttgt ctttccttgg ctggggttga
     5761 acccgtaatt ttaaaggaag tcaggcccaa gtctgacagt tcttgttcaa ttttttccaa
     5821 cattcccttg aactgagaga aaatcaagac acggtgtccg ccgtctgcca cctgtaccag
     5881 taggtctcgg agactatcta gtttgccgct ggctccctga taatcttcca taaacagggc
     5941 aggagtgtca catatttgac gcaagcgcat caaaccagat aaaatttcca cacgacttcg
     6001 ctgaaattcc tgttctgaca cttgagccag atggtctcgc atctgttgta actgggcaag
     6061 gtaaatagcc ttttgctggt cttccagttc atttttataa accacctcaa tcaagtctgg
     6121 caattcagtc agaacttctt ctttcttgcg tcgcatcacg aaaggcttga taaactgagc
     6181 cactcgctct gctggcaatt tcataaattc tttcttgctt ggcaaaagtc cgggcatgac
     6241 gatttggaaa atagaccaca actcacccag atggttttca atcggagttc ctgacaaggc
     6301 aaagaccgac ggcaccacaa attgtctcaa ggtctgggca atcttggtct gggcattttt
     6361 catgacctga gcctcatcta agaaaaggaa gtcaaaggcc atcccctgat aaaactcact
     6421 gtcctgacgg aaggtggcat agctagtcac atagatttga tggctctcgg caagaatctc
     6481 ctcacgactt gctttcaaac catgaacaac agccacatcc aactgtgggg caaatttctg
     6541 aaactcatcc gcccagttgt aaatcaaacc cgacggagcg agaatcaaga ctcgactttc
     6601 ttttgtcact tgactagtca aaaaagcaat ggtctgaagg gttttcccaa gtcccatatc
     6661 atcagccaaa atcccaccaa aaccataatg atggagcatc tgcaaccagc caattccctt
     6721 ttcctgataa tctcgcaagt cagccttgac ctgagttgct tgcaaaggaa agtcctctgg
     6781 atgcgtcaaa tcctgggcca gattctggaa ttcttgtgaa aaagaaacac ggtctcgccc
     6841 ttcaaagaga tgagctaaac tgtaggccaa ggatttccga gcctgcaagg tcccatcttt
     6901 taattcaaat tgccccagtt cctgtagatt ttggcgaatt ttcttggttt cttcatcgaa
     6961 aaagtaaact tgattagacg aatcaatata aaaatcctga ttggcaacca aggcctgcat
     7021 ggcttggtcg atttcctcct gggcaatatt ttgaaaatca aactggattt ccaagagacc
     7081 tcccttggag gcaatctgca cctgaggact cgctaggcta taaagctctt ctagtttatc
     7141 tgataggtca acatgcccga gtttttcaaa gactggaatg atatcatgaa aaaaatgata
     7201 gacagactcc gcttttaagg cctgacgcca agattgaaaa tcggcttcaa agcccgcagc
     7261 caaacagact tggaaaattc tttcttctaa gtccgcgtca cttgaaaatg gtaattcttc
     7321 tagctcttgt cggctagata cctgtctatt tccataatca aactgaattt ctaaacgaat
     7381 ccgattatct tcttccctgt caaagtaaaa agagggcgca aaagttttga tttgtagacg
     7441 ttctggagct gaaacggtgc ccatctggat aaaaagagtc agacaggagg ccaatttgtc
     7501 tcgatcactg ctatcaaatt gcaggtattt ctttccttgt tgacccacag gtaacgcttt
     7561 aatttccttg agaagacgca tctgctggtc tgttaaaaaa taaacctgac ctttatggaa
     7621 aagtactgct ccctgataaa agacattgac cctaggactc tcactgattt ccatttcaaa
     7681 atagtccgag tattctgtta ctgtaaaggc aaatagattg gcatcagcat gcatatcctg
     7741 aaaaagcagg gtttggtagc tatccacttg atggtcaaat tgaaaatggg gcaaggccat
     7801 cagtaaattc acaccctgct caaaaaaggt cagagggaaa aagaggtgcc gaccttggtt
     7861 ttggaaaaag aggtctggaa ccagcccttc ctccgttagt ccgtgcaaga aagtcaaaag
     7921 ttcttggctg gcatcatcaa aggcttccca agaaagagac tcctcataaa tcttgccaat
     7981 catatacgac tttctctgct cgacaatcct taaaaaaagt ggaatatccc gaatgacata
     8041 gtatttttgg ctattgattt ggccgattct cagagtccac aagatatgat tggttcctgc
     8101 ttccacctga cccacagctg ataactcata ggcgcattct gattttggag ataaaattcg
     8161 attcaaaaac ttgccaccca aggtcacctt ggtttcaacg gcctcttttt cttcatgacc
     8221 ttcttccaga ctccacaaga tttcctgacc acgctcatca tttttcagaa aatgctctag
     8281 cgctgccaaa tgcacacagt agcccctctt ttgaaaagaa tcacaggcac aaaaaaccaa
     8341 atcatcctct aaactatagc gcagttcttc ttctgcaacg cgagcgtaga gccgattgtt
     8401 cttttccttg atgatatcaa ccttaccagt ttcataaagg gcaacacctt cgatacgaat
     8461 tttccccgga atcaatttag ccatattttc acctttacct tatcttttta ttataccata
     8521 ttttcgccta tgaaaatagc cttctaggaa gacttttctc ctagaaggct ggatttttaa
     8581 cgtttggcaa aagtagccac aatccgctga cagacttctt gcaacagaga tttgggcata
     8641 gctatattga tgcgggcatg gagacttcct tcctctccaa aatccaaacc acggttgagg
     8701 ataaccttgg cttcatttct caacaactct tgcaatgttt catcagtcag gtcataggct
     8761 gaaaagtcaa gccaaatcaa gtaggtacct tgcggtttca tgaccttgat tttagtctct
     8821 tttccaaata gatccaccac ataattgatg tggtcttcaa agacttgctt gagttcctct
     8881 agccaatctt taccgtatcg ataggcagct tctgtcgcca aataacccaa gcctgaaatt
     8941 tcatgctgat tattggccaa caggcgtttc tggaaagcca gtctcaactt aggattttca
     9001 atgactgcat aggaattttt tgttccagca atattaaatg ttttagtggc actgctcaag
     9061 acgatagcaa aatttttgaa ggcaggattg atggtattga aagactggtg tttgtgacca
     9121 aagagggtca aatcttggtg aatctcatcc gaaactaaca aaacaccgtg tttttggcaa
     9181 agttggccaa tcttctccaa cacttctttt tcccaaacac gtccaccagg attgtgaggg
     9241 ttgcaaagaa tatagagttt aacctcctct tccaccaaat ccttttcaag ttggtcaaag
     9301 tcaatctcaa acagaccatc cttttccact aaggaattag taatcaatct acgattattc
     9361 aacttgacac tgcgagcaaa gggtgggtag acaggcgtgt taattaaaac cgcctcgcct
     9421 tcttttgtaa aggtttgaat agctgttgag atggctggta ccacaccctc gataaagaca
     9481 agagcctctt tgtcaaagtt gtaaccgtat tgtgtagctt cccacttttg aatttcctta
     9541 attaagtctt cactggcata ggtataacca taaaccagtt ggtctgcgta agtttgcacg
     9601 gcttggcgga tttcaggcaa gaccacaaag tccatatccg ctatccaagc tggtagaact
     9661 tcactatccg tttctgtttc tttccattta taggtatggt gccctaaacg gttgggcagg
     9721 cttgtaaaat catattttcc catctttgtc ttatccttct aaggcttggc gcaaatctgc
     9781 aatcaaatct ctagcatcct caatcccaat agacaaacgc aagaggtcat ctgtcaaacc
     9841 ataagaatgg cgtacttctg ctggaatatc agcatgagtt tgagtcgttg gataagtaat
     9901 aagactttcc actccgccca aactttccgc aaaagagaag accttgagac tgttcaaaat
     9961 atgaggaatg cgtgtttcat cggctacttt aaaggaaatc atgcctccac gaccagtgta
    10021 gagaacttcc ttaactgctg gagaatcctt caaaaaggca accacttctt gggcgttagc
    10081 tgttgagcgc tccatacgaa gagataaggt cttgagacca cgaagcaact ggtagctgtc
    10141 aaatggagac aagactgccc ctgttgtatt gagattgtaa aaaagcttct cgtatagttc
    10201 taaactattg gtcacaacca ctccagccaa gacatcattg tggcctgcta gatacttggt
    10261 tgctgaatgg agaacgatat ctgctccatc ttcaatcgga cgttggtaga tagggctata
    10321 gaaggtattg tccaccacca ctttggcacc cttagcatga gccaattttg ctagtttttc
    10381 gatatcaaat tccaacatca agggattggt tggggtttcg atatagagaa catccacatc
    10441 cttttctaac tcggcaatca actcttcttc tgtattggca taggtaaaat ggaaacgacc
    10501 ttcctgctcc acttggttaa accagcgaaa agaaccaccg taaagatcac gcactgccaa
    10561 gaccttactt cctactggaa agacgctaaa ggccagtaca atagctgaca tccctgagct
    10621 agtcgctagg gcatagtctg ctgactcaat agccgccaag acttcctcag ccttactacg
    10681 agttggattt ttagtgcgcg tatagtcaaa cccagtagat cgaccaaact ctggatgctg
    10741 ataggtcgtt gaaaaatgaa gcggtgtcac caatgcacct gtcgcttcat ctgacttaat
    10801 acccgcctgg gccaaaattg tgttaatgtg taattccttg ctcatacaat acctccaaat
    10861 ctatagtaac tattgtacca cttattttca tcaactcatt ttcttctttt caagagctag
    10921 ttatagtttc aaactatata aaaagggagt ttttcctgct ccctttaata gactataaaa
    10981 tggtgaatct caaaagacac cttcactcta tcatttgctc ctgcacaaaa cgagcataac
    11041 gctcatgatt ttccagtagt tccttatgag ttcctgagcc agtgattttc ccctcctcta
    11101 agaagaaaat acaatccaca tcttttaccg ttgacaaacg atgcgctata atcacaaccg
    11161 tcttctcctt taatacagaa tagaggctac tgataatcgc atactcagaa tccgcatcaa
    11221 gattagcagt ggcttcatca aatataagaa tttcagcatc ttttaagtag gctctagcta
    11281 tttgaagtct ttggctttgc ccccctgaca agagtcgtcc gcgttcacca acttcagtat
    11341 ctagtccctc tttcatggag cgaatctcat cacctagtga tactaagtct agcactttca
    11401 tcaattcatc atcagttact aagcgattca aaccgagaca aagattgtca cgaatactgc
    11461 cagataagac tgcattattt tgtgaaaccc aagcgatttt acttctccat tcttttaagt
    11521 taaaatcata tatacttgat tgctccatta gaatatctcc tgaaagcggt ttataaaacc
    11581 gctctaacaa acgcacaatc gttgattttc ctgatccaga tggtccaaca aaagcaattt
    11641 tttgcccctt gaaaattgaa caagtaatat cctttaagac aggtcgattt tcatcataac
    11701 caaaatagac atggtt
//
LOCUS       DAVBOG010000058        11434 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.058, whole genome shotgun sequence.
ACCESSION   DAVBOG010000058 DAVBOG010000000
VERSION     DAVBOG010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11434)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11434)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11434
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.058"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ865_001830"
     CDS             complement(103..2100)
                     /gene="metG"
                     /locus_tag="VQ865_001830"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006155678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HET3136133.1"
                     /translation="MSEKNFYITTPIYYPSGKLHIGSAYTTIACDVLARYKRLMGYDV
                     FYLTGLDEHGQKIQQKAEEAGITPQAYVDGMAVGVKELWQLLDISYDKFIRTTDDYHE
                     KVVAQVFERLLAQDDIYLGEYSGWYSVSDEEFFTESQLAEVFRDEAGNVTGGIAPSGH
                     EVEWVSEESYFLRLSKYQDRLVEFFKAHPEFITPDGRLNEMLRNFIEPGLEDLAVSRT
                     TFTWGVPVPSNPKHVVYVWIDALLNYATALGYAQDEHGNFDKFWNGTVFHMVGKDILR
                     FHSIYWPILLMMLDVKLPDRLIAHGWFVMKDGKMSKSKGNVVYPEMLVERYGLDPLRY
                     YLMRNLPVGSDGTFTPEDYVGRINYELANDLGNLLNRTVSMINKYFDGQIPAYVEGVT
                     EFDHVLAEVAEQSIADFHTHMEAVDYPRALEAVWTLISRTNKYIDETAPWVLAKDEAL
                     RDQLASVMSHLAASIRVVAHLIEPFMMETSRAVLTQLGLEEVSSLENLSLADFPADVT
                     VVAKGTPIFPRLNMEEEITYIKEQMEGNKPAVEKEWNPDEVELKLNKDEIKFEDFDKV
                     EIRVAEVKEVSKVEGSDKLLQFRLDAGDGEDRQILSGIAKYYPNEQELVGKKVQIVAN
                     LKPRKMMKKYVSQGMILSAEHDGKLTLLTVDPAVPNGSVIG"
     gene            complement(2224..3483)
                     /locus_tag="VQ865_001831"
     CDS             complement(2224..3483)
                     /locus_tag="VQ865_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001180420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136134.1"
                     /translation="MQNLKFAFSSIMAHKMRSLLTMIGIIIGVSSVVVIMALGDSLSR
                     QVNKDMTKSQKNISVFFSPKKSKDGSFTQKQSAFTVSGKEEEVPVEPPKPQESWVQEA
                     AKLKGVDSYYVTNSTNAILTYQDKKVENANLTGGNRTYMDAVKNEIIAGRSLREQDFK
                     EFASVILLDEELSISLFESPQEAINKVVEVNGFSYRVIGVYTSPEAKRSKIYGFGGLP
                     ITTNISLAANFNIDEIASIVFRVNDTSLTPTLGPELARKMTELAGLQQGEYQVADESV
                     VFAEIQQSFSFMTTIISSIAGISLFVGGTGVMNIMLVSVTERTREIGLRKALGATRAN
                     ILIQFLIESMILTLLGGLIGLTIASGLTALAGLLLQGLIEGIEVGVSIPVALFSLAVS
                     ASVGMIFGVLPANKASKLDPIEALRYE"
     gene            complement(3485..4186)
                     /locus_tag="VQ865_001832"
     CDS             complement(3485..4186)
                     /locus_tag="VQ865_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136135.1"
                     /translation="MKQLISLKNIFRSYRNGDQELQVLKNINLEVNEGEFVAIMGPSG
                     SGKSTLMNTIGMLDTPTSGEYYLEGQEVAGLGEKQLAKVRNQQIGFVFQQFFLLSKLN
                     ALQNVELPLIYAGVSSSKRRKLAEEYLDKVELTERSHHLPSELSGGQKQRVAIARALV
                     NNPSIILADEPTGALDTKTGNQIMQLLVDLNKEGKTIIMVTHEPEIAAYAKRQIVIRD
                     GVISSDSAQLGKEEN"
     gene            complement(4170..5369)
                     /locus_tag="VQ865_001833"
     CDS             complement(4170..5369)
                     /locus_tag="VQ865_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HET3136136.1"
                     /translation="MKKKNGKAKKWQLYAAIGAASVVVLGAGGILLFRQPSQTAVKDE
                     PTHLVVAKEGSVASSVLLSGTVTAKNEQYVYFDASKGDLDEILVSVGDKVSEGQALVK
                     YSSSEAQAAYDSASRAVAKADRHINELNQARNEAASAQAPQLPAPVGGEDATVQSPTP
                     VAGNSVASIDAQLGDARDARADAAAQLSKAQSQLDATTVLSTLEGTVVEVNSNVSKSP
                     TGASQVMVHIVSNENLQVKGELSEYNLANLSVGQEVSFTSKVYPDKKWTGKLSYISDY
                     PKNNGEAASPAAGNNTGSKYPYTIDVTGEVGDLKQGFSVNIEVKSKTKAILVPVSSLV
                     MDDSKNYVWIVDEQQKAKKVEVSLGNADAENQEITSGLTNGAKVISNPTSSLEEGKEV
                     KADEATN"
     gene            5634..6980
                     /gene="gor"
                     /locus_tag="VQ865_001834"
     CDS             5634..6980
                     /gene="gor"
                     /locus_tag="VQ865_001834"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015511376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HET3136137.1"
                     /translation="MREYDIIAIGGGSGGIATMNRAGEHGAKAAVIEEKKLGGTCVNV
                     GCVPKKIMWYGAQIAETFHQFGEDYGFKTTDLNFDFATLRRNREAYIDRARSSYDSSF
                     KRNGVDLIEGHAEFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAELGGSSDDVF
                     AWEELPESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEME
                     RINLPLHTHKVPAKLEKTAKGITIHFEDGTSHTASQVIWATGRRPNVKSLQLEKAGVT
                     LNERGFIQVDEYQNTVVEGIYALGDVTGEKELTPVAIKAGRTLSERLFNGKTTAKMDY
                     STIPTVVFSHPAIGTVGLTEEQAIKEYGQDQIKVYKSSFTSMYSACTCNRQETRFKLI
                     TAGSEEKVVGLHGIGYGVDEMIQGFAVAIKMRATKADFDATVAIHPTSSEEFVTMR"
     gene            7176..7712
                     /locus_tag="VQ865_001835"
     CDS             7176..7712
                     /locus_tag="VQ865_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000709035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HET3136138.1"
                     /translation="MKKAHVYAIPAIGAALIAVLAQISLPIGPVPFTLQNFAIGLIAT
                     VFRPREAVLSAGLYLLLGAIGLPVFAGGGAGFQALVGPTAGYLWFYLVYSGLTSSLTN
                     SKSGVVKIFLANLLGDALVFVGGILSLHFLAGMAFEKALAVGVLPFIIPDLGKLLAIS
                     FISRPLLQRLKNQAYFTN"
     gene            7763..7849
                     /locus_tag="VQ865_001836"
                     /pseudo
     CDS             7763..7849
                     /locus_tag="VQ865_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(7918..8133)
                     /locus_tag="VQ865_001837"
     CDS             complement(7918..8133)
                     /locus_tag="VQ865_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000807422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HET3136139.1"
                     /translation="MAEFTFEIEEHLLTLSENEKGWTKEINRVSFNGAPAKFDIRAWS
                     PDHTKMGKGITLSNEEFQTMVDAFKGN"
     gene            8231..8551
                     /locus_tag="VQ865_001838"
     CDS             8231..8551
                     /locus_tag="VQ865_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001216095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136140.1"
                     /translation="MRHKFQQVLNKIHDFLNGYDQPDQTETNSLTATIEEAIQKQTAV
                     HLILSETSFTGDIIKYDQQGQQIIVKNFAKNVSRIIRISDIQRLRFVPSTVQTAQKNR
                     FKKE"
     gene            complement(8582..8920)
                     /locus_tag="VQ865_001839"
     CDS             complement(8582..8920)
                     /locus_tag="VQ865_001839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001196050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136141.1"
                     /translation="MQVIKRNGEIAEFNPDKIYQAILKAAQTVYVLTDDLRQNLAQVT
                     KKVVLDLQEAKVERATISMIQSMVEHRLLGAGYITIAEHYISYRLQRDLERSGYGDHI
                     AVHLHFEQIR"
     gene            complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ865_001840"
     CDS             complement(8932..9651)
                     /gene="trmD"
                     /locus_tag="VQ865_001840"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HET3136142.1"
                     /translation="MKIDILTLFPEMFSPLEHSIVGKAREKGLLDIQYHNFRENAEKA
                     RHVDDEPYGGGQGMLLRAQPIFDSFDAIEKKNPRVILLDPAGKQFDQVYAEDLAQEEE
                     LIFICGHYEGYDERIKTLVTDEISLGDYVLTGGELAAMTMIDATVRLIPEVIGKESSH
                     QDDSFSSGLLEYPQYTRPYDYRGMVVPDVLMSGHHEKIRQWRLYESLKKTYERRPDLL
                     EHYQLTVEEEKMLAEIKENKE"
     gene            complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ865_001841"
     CDS             complement(9641..10159)
                     /gene="rimM"
                     /locus_tag="VQ865_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016465641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HET3136143.1"
                     /translation="MNYFNVGKIVNTQGLQGEMRVLSVTDFAEERFKKGAELALFDEK
                     DQFVQTVTIASHRKQKNFDIIKFKDMYHINTIEKYKGYSLKVAEEDLNDLDDGEFYYH
                     EIIGLEVYEGDSLVGTIKEILQPGANDVWVVKRKGKRDLLLPYIPPVVLNVDIPNKRV
                     DVEILEGLDDED"
     gene            complement(10190..10978)
                     /locus_tag="VQ865_001842"
     CDS             complement(10190..10978)
                     /locus_tag="VQ865_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3136144.1"
                     /translation="MKRFEVSTEIGSLSVTYQKQKKVLVCLNGAGLLPSYENFSLILE
                     KPPPTIGYLTIDFPNTGRSPIHDQAGKNLDNLADAVYEVLEELGISEYILCAHSWSGI
                     LACKLLEKPIKRQTLVAIEPTTKKVMFADFSENPYPEMEEQMRLIDECGPELYFKNLT
                     QATFSPETNKKIWELMQEKGLELENQDPEFQISGEITEEDFENLSIESHVPVFIFCQT
                     YREKEYRESEYWTSNTKLILGRNHHYLQWSESEKIAAIIRELSE"
     gene            complement(11082..11325)
                     /locus_tag="VQ865_001843"
                     /pseudo
     CDS             complement(11082..11325)
                     /locus_tag="VQ865_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000779614.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
BASE COUNT         3284 a         2512 c         2080 g         3558 t
ORIGIN      
        1 cagtgctttg atcaacccgc ggctagcttc ctagtttgct ctttgatttt cattgagtat
       61 aaataaaaaa acagaactag tctgaactag tcctgtctac ttttacccaa tcacacttcc
      121 atttggtaca gctggatcaa ctgtgagaag ggttaatttg ccatcatgtt cagctgatag
      181 aatcataccc tggctgacat attttttcat cattttacgt ggtttgaggt tagcaacgat
      241 ttgaactttc ttgccgacca attcttgttc atttggatag tattttgcaa ttcctgaaag
      301 aatctgacga tcttctccat caccagcatc caagcggaat tgaagcaact tatctgaacc
      361 ttctacttta gacacttctt tgacttctgc gacacggatt tcaaccttgt caaagtcttc
      421 aaacttgatt tcatccttgt ttagtttgag ctcaacttcg tccggattcc attctttttc
      481 gactgctggt ttattgcctt ccatttgttc cttgatatag gtgatttctt cttccatatt
      541 tagacgtgga aagataggtg ttcctttggc aactacagtc acatctgctg ggaagtcagc
      601 caaactcaag ttttcaagac tagaaacttc ttccaaacca agttgagtca aaactgcacg
      661 actagtttcc atcataaatg gttcaatcaa gtgagcaact acacgaatgc tggctgccaa
      721 gtggctcatg acacttgcca attggtcacg aagagcttca tccttggcca agacccatgg
      781 tgcggtctca tcgatgtatt tattggtacg agagatcaga gtccagactg cttcaagcgc
      841 acgtggatag tcaactgctt ccatgtgtgt atggaagtct gcgattgatt gttctgcaac
      901 ctcagcaaga acatgatcaa attcagtcac accttctaca taggcaggga tttgtccatc
      961 aaagtactta ttaatcatgg aaaccgtacg gttaaggagg ttcccaaggt cattagccaa
     1021 ttcatagttg atacggccga catagtcttc aggagtaaag gttccgtctg aaccaactgg
     1081 aaggttacgc atgaggtagt aacgaagtgg atctagtcca taacgctcta ccaacatttc
     1141 agggtaaacg acattccctt ttgacttaga catttttccg tctttcatga caaaccaacc
     1201 atgggcaatc aaacgatcag gtaatttaac atccaacatc ataagaagga ttggccagta
     1261 gatagagtgg aagcgaagga tatcttttcc taccatatgg aagactgttc cattccagaa
     1321 cttgtcaaag ttaccatgtt cgtcttgagc gtagccaaga gctgtcgcat agttaagaag
     1381 ggcatcaatc caaacgtaga caacgtgttt tggatttgat gggacaggca ctccccatgt
     1441 aaaggttgta cgagataccg ccaaatcttc caaacctggc tcgatgaagt tgcgtagcat
     1501 ttcattaagg cgaccatctg gcgtgataaa ttcaggatga gctttgaaaa attcgaccaa
     1561 acggtcttgg tatttgctaa ggcgaagaaa gtatgattct tcagaaaccc attcaacctc
     1621 atggcctgat ggagcaatac caccagtcac atttccagct tcatcacgga aaacttctgc
     1681 cagctggctt tctgtaaaga attcttcgtc tgatactgaa taccaaccag agtattcacc
     1741 caagtagata tcatcttgag caagtaagcg ttcaaagact tgtgcgacaa ctttttcatg
     1801 gtagtcatca gttgtacgga taaatttatc gtatgagata tctagtaatt gccagagttc
     1861 tttaactcca accgccattc catcaacata ggcttgaggt gtaataccag cttcttccgc
     1921 tttctgctgg attttctgac catgttcatc aagacctgtc agataaaata catcgtagcc
     1981 catcaggcgt ttgtaacgtg ctaggacatc acatgcgata gttgtgtagg cagaaccgat
     2041 atgaagtttc ccagatggat agtaaatcgg cgttgtaata taaaaatttt tttcagacat
     2101 aatttttcct ttccaggcaa atgaaacctg tttttctaac acttcattat atcacatttt
     2161 taatgaattt cgatagggaa atccatacaa aaacaagata gacgagtgtc catcttgttg
     2221 atctcattca taacgaaggg cttcaattgg atcaagtttc gatgccttgt tggctggcaa
     2281 gactccaaaa atcataccaa cactagccga aactgcaaga ctaaataggg caactgggat
     2341 tgatactcca acttctatac cttctattaa accttgcagt aacaaacctg ctaaggcagt
     2401 taaaccactt gcaattgtca agccaattaa gccacctaac aaggtcaaaa tcatggattc
     2461 aatcaaaaac tgaattaaaa tattggcacg tgttgcgccc aaagccttac gaagaccaat
     2521 ctcacgagtg cgctctgtca ccgaaaccag catgatgttc atgacaccag ttcctccaac
     2581 aaagagagaa atccctgcga tggaactaat aatcgtcgtc ataaaactaa acgattgttg
     2641 aatttctgca aatacaacgg actcatctgc cacctggtat tctccctgtt gtaagcctgc
     2701 aagctctgtc atttttcgtg ccagttctgg acccagagtt ggggttaaac tggtatcatt
     2761 cactcgaaag acaatactag ctatttcatc tatattaaaa ttcgcagcaa gggagatatt
     2821 ggtagtaata ggcaagccac caaacccata tatttttgac cttttagcct ccggactagt
     2881 ataaacccca atgacccggt aactaaatcc attgacttct acaaccttgt taatagcctc
     2941 ttgaggagat tcaaataaac taatggacaa ttcctcatct agcaaaataa cacttgcaaa
     3001 ctctttgaaa tcttgctctc tcagactacg acctgcaata atttcattct taacagcgtc
     3061 catgtaagtt ctgtttccac ctgtcaaatt agcattctca acctttttat cttgataggt
     3121 caagatggca ttcgttgaat tggttacata gtaactatcc actcccttca gtttagctgc
     3181 ctcttgaacc caggattctt gcggttttgg cggttcaaca ggaacttcct cttcctttcc
     3241 agaaaccgta aaagctgatt gtttctgagt aaaagaccca tctttacttt ttttaggaga
     3301 gaaaaagacg ctaatatttt tctgagattt agtcatatct ttattgactt gacgagatag
     3361 ggaatcaccc aaagccataa tcacaacaac tgatgaaaca ccgataataa tcccaatcat
     3421 agtaagcaaa gaacgcatct tgtgagccat gatagatgaa aaggcaaatt tcagattctg
     3481 catcttagtt ttcctccttt cctaactgag cactgtcaga cgaaatgacc ccatcccgaa
     3541 tgacaatctg acgtttggca taggcagcaa tctcaggctc atgcgttacc atgataatgg
     3601 tttttccttc tttattcaaa tcaaccaata attgcataat ttggttacct gttttggtat
     3661 ccaaggctcc tgtcggttca tccgctagga taatagaagg attgtttacc aaggcacgcg
     3721 caatggctac acgttgcttt tgaccaccag ataattctga aggtaaatgg tgactacgtt
     3781 ctgtcaattc aaccttgtct aaatattcct cagccaactt gcgacgtttt gaagacgaaa
     3841 ctcctgcgta aatcaagggc aattctacat tttgcagagc attgagcttc gatagaagaa
     3901 agaactgctg aaagacaaaa ccgatttgtt ggttacgaac cttagctagt tgtttttcac
     3961 caagcccagc cacttcttga ccttcaagat aatattctcc actggttggt gtatccaaca
     4021 tgccaatcgt attcatcaga gtggacttac cagaaccaga tggccccatg atggctacaa
     4081 attcaccctc attcacttct agattgatat ttttgagaac ctgcagttct tggtcaccat
     4141 tacggtagct tctgaagata ttttttagac taattagttg cttcatcagc cttcacctct
     4201 tttccttctt ccaaggaaga tgttggatta ctgatgacct tagcaccatt tgtcaaacca
     4261 gaagtgattt cttgattttc tgcgtcagca tttcccaatg aaacctcaac ttttttagcc
     4321 ttttgttgtt catccacaat ccagacataa tttttactat catccattac tagactgcta
     4381 acaggaacaa gaatagcctt agttttgctt ttaacctcaa tgttgacaga aaaaccttgt
     4441 ttcaaatcac caacctcgcc tgtcacatca atagtataag ggtatttaga acctgtatta
     4501 ttcccggctg ctggactagc tgcttcacca ttgtttttag gatagtcaga aatatagctt
     4561 aatttcccag tccatttttt atcaggatac actttagaag taaagcttac ttcttgacct
     4621 acagaaaggt tggctagatt gtactcagac aattctccct tgacttgtaa attttcattg
     4681 ctgacaatat gaaccataac ttgactcgcc cctgttggag atttagaaac attgctattg
     4741 acttcgacta cagttccctc tagggtactg agaacagttg ttgcatccaa ttgactttga
     4801 gccttgctta attgcgctgc agcatctgca cgcgcatcac gggcatcacc caattgagca
     4861 tcaatagaag caacagaatt tccagccact ggagttgggc tttgcaccgt tgcatcttct
     4921 cctcctactg gcgctggtaa ctgtggagcc tgagctgaag cggcttcatt tcgtgcttga
     4981 ttgagttcat tgatatgacg atctgcctta gctactgctc gactagctga atcataggcc
     5041 gcctgcgctt ctgaactact gtacttgact aaagcctgcc cttcgctgac cttatcgccc
     5101 acagaaacaa ggatttcatc taaatcaccc ttactagcat caaaataaac atattgttca
     5161 ttttttgctg ttactgtccc tgacaataaa acagaggatg ccacgcttcc ttccttggca
     5221 acaacaagat gagtaggctc atcttttaca gcagtctgag aaggttgtct aaaaagtaaa
     5281 atccccccgg cacccaatac aactacactc gcagcaccga ttgctgcata cagttgccac
     5341 tttttagctt taccattctt tttcttcata atgaaactcc ttttcttttt tacaatactt
     5401 tgctattata ccaaatttcc ctccagcaaa caatacagtt caggattaag caatcgttcg
     5461 gaatttttct tttctattgt actagatata taatacacta tcttgactta tttggcaagc
     5521 ttttttgcaa ttttttgtgc gtagcagatt tttgcaatca aatcaaaaaa agaataaaat
     5581 ataactatca aaaaagacgc tctactattt aaaagattac aaaggagttt tcaatgagag
     5641 aatatgatat cattgctatc ggtggaggta gcggaggaat cgctaccatg aaccgtgctg
     5701 gtgaacatgg agccaaagca gccgttattg aggaaaagaa attaggtgga acctgtgtca
     5761 acgtcggttg tgttcctaaa aaaatcatgt ggtacggggc gcaaatcgct gagactttcc
     5821 atcaatttgg agaagactac ggctttaaga ctactgatct taactttgac tttgcaaccc
     5881 tacgtcgcaa tcgtgaagcc tacattgatc gcgctcgttc ttcttatgat agtagtttta
     5941 aacgcaacgg tgtagacttg attgaaggtc atgctgaatt tgtagattct catactgtaa
     6001 gcgtaaatgg tgaactgatt cgtgctaaac atatcgtgat tgctacaggt gcccatccaa
     6061 gtattcctaa tattcctggt gctgagctag gtggctcttc tgatgatgta tttgcctggg
     6121 aagaacttcc agagtcagtt gccattctag gcgctggtta tatcgccgtt gaattagctg
     6181 gcgtactcca cacttttggt gtcaagacag atctctttgt tcgccgcgat cgtcctttac
     6241 gtggttttga ttcctacatc gttgaaggtt tggtcaagga aatggaaaga ataaacttgc
     6301 cacttcatac tcacaaagtc cctgccaagt tagaaaaaac tgctaaaggc attaccattc
     6361 atttcgagga tggtaccagt cacacagcta gccaagttat ctgggctaca ggtcgccgtc
     6421 caaacgttaa gagcttgcaa cttgaaaaag ctggagtgac tctgaatgaa cgtggcttta
     6481 tccaagtaga tgaataccaa aatactgttg ttgagggaat ctatgctcta ggtgatgtaa
     6541 caggtgaaaa agaactgact ccagttgcaa tcaaggctgg gcgtacccta tcagaacgtc
     6601 tctttaacgg aaaaacaact gcaaaaatgg attactcaac tattccaact gttgtctttt
     6661 cacaccctgc tatcggaact gttggtttga cagaagaaca agctattaaa gaatacggtc
     6721 aagaccaaat caaggtttac aaatcaagct ttacttctat gtactctgct tgcacttgca
     6781 accgtcaaga aactcgtttc aaattgatca cagctggttc agaagaaaaa gttgtcggac
     6841 ttcacggaat tggctacggc gttgatgaaa tgattcaagg atttgctgtt gctatcaaaa
     6901 tgagagcaac caaggctgac tttgacgcaa ctgtagcgat tcacccaact tcatctgaag
     6961 aatttgtaac catgcgttaa tcgaaacaaa agaagctgat ataaatatgt ctgcttcttt
     7021 tttaatgatt ttcgaatcaa caaaaaatta tccaacttga ctagtcacga aaatcggctg
     7081 ttacagtttt tgttaccttg tttttaaaaa atggttgaca tcgactccta tatgagtata
     7141 atagttacta tacattagaa aagaggttaa ctattttgaa aaaagctcac gtttatgcta
     7201 tccctgctat tggggctgct ctcattgctg ttttggcaca aatcagtctt ccaattggac
     7261 ctgttccctt cactctgcaa aactttgcaa tcggcttgat tgctactgtc tttagaccga
     7321 gagaggctgt actttctgct ggactctatc ttcttctagg tgctatcggt cttcctgtct
     7381 ttgcaggagg tggagctggt tttcaggctt tagttggccc tactgcaggc tatctttggt
     7441 tttatctcgt ttactctgga cttacttcct ctctaaccaa cagcaagagt ggtgttgtta
     7501 agatttttct tgcaaacctc ttgggtgatg cccttgtctt tgtcggcggg attctcagct
     7561 tgcatttcct agctggaatg gcatttgaaa aagctcttgc tgtgggggtt cttcccttta
     7621 tcattccaga ccttggcaaa cttctggcta ttagttttat tagccgtccc ctacttcaac
     7681 gccttaaaaa tcaggcttac tttactaact aaaaaaggat atcgagttat catgactcaa
     7741 tatccttttc ttttattttg aaaacttata ctcaatgaaa atcaaagagc aaactagaaa
     7801 gctagccgca ggctgctcaa aacactgttt tgaggttgtg gatgaaactg acgaagtcag
     7861 taaccataca tacggcaagg caaagctgac gcggtttgaa gagattttcg aagagtatta
     7921 gttgccttta aaggcatcca ccatcgtttg aaattcttca tttgagagag taatcccttt
     7981 gcccatttta gtatggtctg gactccaagc acgaatatca aactttgcag gggcaccatt
     8041 aaagctcaca cggttaattt ccttggtcca acctttttcg ttttcagaaa gagtcaacaa
     8101 gtgctcttcg atttcaaatg taaattctgc cattttcttc tcctttttta gtttcattag
     8161 tttattcgta aaatcttgta gattttagga aaattttata taatattgat ataaaagaag
     8221 ggaggccaat atgagacata aattccagca agttctaaat aaaatacatg attttttaaa
     8281 tggatatgac caacctgacc agactgaaac caactccctt acagccacta ttgaagaggc
     8341 tatccagaaa caaaccgctg ttcaccttat cttgtctgag acaagtttta caggtgatat
     8401 catcaaatat gatcagcaag gccagcaaat tatcgtgaaa aattttgcca aaaatgtgag
     8461 ccggattatc cgtataagcg atattcaacg cctgcgattt gtcccctcaa ctgtccaaac
     8521 agcccaaaaa aatagattta agaaagagtg agatgtagtt gcttcatccc actctttttt
     8581 cttagcgaat ttgttcaaaa tgtaaatgaa ctgcaatatg atctccataa ccacttcttt
     8641 ccaagtcacg ttgtaaacga taggaaatgt agtgttctgc aatggtaatg taacctgcgc
     8701 ccaataaacg atgttcaacc atagattgaa tcatactgat agtcgcacgt tccaccttgg
     8761 cttcttgtaa atccaaaact accttcttag tgacttgagc aagattttga cgcaaatcat
     8821 ctgtcaaaac ataaacagtt tgggctgcct tcaagatggc ttggtaaatc ttatctggat
     8881 taaattcagc aatttcgcca ttacgtttga ttacttgcat aggtttctcc tttattcttt
     8941 gttttctttg atttctgcca gcattttttc ttcttctact gtcagttgat aatgttcaag
     9001 taaatccggt ctgcgctcgt aggttttctt taaactctcg tacaatcgcc actgacgaat
     9061 cttttcatgg tggccactca tcaatacatc tggcacgacc atgcctcgat aatcataggg
     9121 acgtgtgtac tgaggatatt ctaaaagacc tgaagaaaaa ctatcatctt ggtggctaga
     9181 ctccttgcca atcacttctg gaatcaggcg aactgtagca tcaatcatgg tcatagctgc
     9241 caattctcca ccagtgagga catagtcgcc tagggaaatc tcatctgtta ccaaggtctt
     9301 aatgcgctca tcataaccct catagtgccc acagataaag attagctctt cctcttgagc
     9361 caaatcttca gcataaacct gatcaaactg ctttccagca ggatcgagga gaataacgcg
     9421 cggatttttc ttttcaatag catcaaagga atcgaaaata ggttgtgctc tgagcaacat
     9481 gccctgaccg cctccgtagg gctcatcatc tacatgacgg gccttttcag cattttctcg
     9541 aaaattatga tactggatat ccaagagccc tttttctcga gcctttccaa cgattgagtg
     9601 ctccagtgga gaaaacatct ctggaaagag ggttaaaata tcaatcttca tcgtctaacc
     9661 cttctaagat ttccacatcg acccgtttat ttggaatatc aacattgaga accactggtg
     9721 ggatataagg taaaagcaaa tcacgtttgc cttttcgttt gaccacccag acatcattag
     9781 cacctggttg caggatttcc ttgatggttc caaccaagct atcaccctca tagacttcca
     9841 aaccgataat ctcgtgatag taaaattcac catcgtctag gtcattcaaa tcttcctcag
     9901 cgaccttgag actgtatccc ttgtactttt cgatagtatt gatatggtac atatctttga
     9961 atttaataat gtcaaagttc ttctgtttac ggtggctagc gatggtcact gtttggacaa
    10021 actgatcttt ttcatcaaac aaagccagct cagctccttt tttaaaccgt tcttctgcaa
    10081 aatccgtcac agacaagact cgcatctcac cctgtaatcc ctgcgtatta acgattttcc
    10141 caacattaaa gtagttcatc ttgtctcctg taatctcctt ttttccatct tattctgaca
    10201 attctcgaat aatagccgca attttttccg attctgacca ttgtaaataa tggtgattcc
    10261 ttcctaaaat gagtttagta ttggaagtcc aatattctga ttctctgtac tctttttctc
    10321 tataagtctg acaaaaaata aatacaggga catgagattc tatcgacaaa ttctcaaaat
    10381 cttcctcagt aatctctcca gatatctgaa attctggatc ttgattttcc aactctaagc
    10441 ctttttcttg cattaattcc cagatttttt tattcgtttc aggactaaat gttgcttgag
    10501 ttaagttctt aaaataaagt tcaggaccac actcgtcaat cagcctcatc tgctcttcca
    10561 tttctggata aggattttct gaaaaatcag caaacatgac ttttttagtt gtcggttcaa
    10621 ttgctactaa agtctgacgc ttaattggtt tctcgagtaa tttgcaagct aaaattccac
    10681 tccaactatg tgcacaaagt atatattcag aaattcctaa ttcttcaagt acttcataaa
    10741 ccgcatctgc aagattatct agattttttc cagcttggtc atgaatcgga ctcctacctg
    10801 tgttcggaaa atcaattgtc aaataaccaa ttgtaggagg aggtttttca agtataagtg
    10861 aaaaattttc ataacttggt agcaaacctg ctccgtttag acaaactagc actttctttt
    10921 gcttttgata agtaacagag aggctaccaa tttctgtaga tacttcaaac ctcttcataa
    10981 agaaatccac tcattctata taatgaatta ttaaaaatcc ttatccttta ttttatcacg
    11041 ttccaaagat tttctcaagt tggaggaagg ggacaacatc tctactttcc cttcaagaat
    11101 ccttccaaat catgtttatg ttggtaatta acggctgcgg ttttgtcttt ctcaaagatg
    11161 gttctagtta ggtcaatatg cttgatagca gcaatagcga cggtgtagtg aatgatatca
    11221 gccagttcta tggcaggttc ctcgttcgaa tcctatccct tcttttcgac cagagcgcct
    11281 attcaaaacc tcggctactt ctccgacttc ctccactaac ttcataaaga gaccttcatc
    11341 agtccgagac tgctgttaat gttcgagtaa gtagtcttgg aattgcctaa acgttcaatc
    11401 ttttatagta tattgaaact agaatagtac acct
//
LOCUS       DAVBOG010000059        11266 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.059, whole genome shotgun sequence.
ACCESSION   DAVBOG010000059 DAVBOG010000000
VERSION     DAVBOG010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11266
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.059"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ865_001844"
     CDS             complement(392..1528)
                     /gene="dnaJ"
                     /locus_tag="VQ865_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001066288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HET3136145.1"
                     /translation="MNNTEFYDRLGVSKNASADEIKKAYRKLSKKYHPDINKEPGAED
                     KYKEVQEAYETLSDDQKRAAYDQYGAAGANGGFGGAGGFGGFNGAGGFGGFEDIFSSF
                     FGGGGSSRNPNAPRQGDDLQYRVNLTFEEAIFGTEKEVKYHREAGCRTCNGSGAKPGT
                     SPVTCGRCHGAGVINVDTQTPLGMMRRQVTCDVCHGRGKEIKYPCTTCHGTGHEKQAH
                     SVHVKIPAGVETGQQIRLAGQGEAGFNGGPYGDLYVVVSVEASDKFEREGTTIFYNLN
                     LNFVQAALGDTVDIPTVHGDVELVIPEGTQTGKKFRLRSKGAPSLRGGAVGDQYVTVN
                     VVTPTGLNDRQKVALKEFATAGDLKVNPKKKGFFDHIKDAFDGE"
     gene            complement(1733..2086)
                     /locus_tag="VQ865_001845"
     CDS             complement(1733..2086)
                     /locus_tag="VQ865_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000115730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136146.1"
                     /translation="MSVNKNNLSDIADYHEKIKFFEELFNLDYNPTEMLVTVERNGNV
                     IYKEFTEVAVGKSKYDYTSVFKDVMIYFSDHICQELHLYKTQDPHYNKFEFDLAKRSL
                     KITTRDNTTIFISNE"
     gene            complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ865_001846"
     CDS             complement(2099..3922)
                     /gene="dnaK"
                     /locus_tag="VQ865_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002946936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HET3136147.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGTESKIIANPEGNRTTPSVVSFKN
                     GEIIVGDAAKRQAVTNPDTVISIKSKMGTSEKVSANGKEYTPQEISAMILQYLKGYAE
                     DYLGEKVTKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTDK
                     EEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNKLGGDDFDQKIIDHLVAEFKKEN
                     GIDLSTDKMAMQRLKDAAEKAKKDLSGVTSTQISLPFITAGEAGPLHLEMTLTRAKFD
                     DLTRDLVERTKVPVRQALSDAGLSLSEIDEVILVGGSTRIPAVVEAVKAETGKEPNKS
                     VNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTSK
                     SQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDIDK
                     NGIVSVKAKDLGTQKEQTIVIQSNSGLTDEEIDRMMKDAEANAEADKKRKEEVDLRNE
                     VDQAIFATEKTIKETEGKGFDAERDAAQAALDDLKKAQEDNNLDDMKAKLEALNEKAQ
                     GLAVKLYEQAAAAQQAQEGAEGAQATGNAGDDVVDGEFTEK"
     gene            complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ865_001847"
     CDS             complement(4402..4926)
                     /gene="grpE"
                     /locus_tag="VQ865_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HET3136148.1"
                     /translation="MAQDIKNEEVEEVQEEEVVETAEETTPEKSELDLANERADEFEN
                     KYLRAHAEMQNIQRRANEERQNLQRYRSQDLAKAILPSLDNLERALAVEGLTDDVKKG
                     LGMVQESLIHALKEEGIEEIAADGEFDHNYHMAIQTLPADDEHPVDTIAQVFQKGYKL
                     HDRILRPAMVVVYN"
     gene            complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ865_001848"
     CDS             complement(4953..5987)
                     /gene="hrcA"
                     /locus_tag="VQ865_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011999912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HET3136149.1"
                     /translation="MVTERQQDILNLIIDIFTKTHEPVGSKALQESINSSSATIRNDM
                     AELEKQGLLEKAHTSSGRMPSVAGFQYYVKHSLDFHRLAENEVYEIVKAFDQEFFKLE
                     DILQEAANLLTDLSGCTVVALDVEPSRQRLTAFDIVVLGQHTALAVFTLDESRTVTSQ
                     FLIPRNFLQEDLLKLKSIIQERFLGHTVLDIHYKIRTEIPQIIQRYFTTTDNVIDLFE
                     HIFKEMFNENIVMAGKVNLLNFANLAAYQFFDQPQKVALEIREGLREDQMQNVRIADG
                     QESCLADLAVISSKFLIPYRGVGILAIIGPVNLDYQQLINQINVVNRVLTMKLTDFYR
                     YLSSNHYEVH"
     gene            complement(6151..6660)
                     /locus_tag="VQ865_001849"
     CDS             complement(6151..6660)
                     /locus_tag="VQ865_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001088691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2812 domain-containing protein"
                     /protein_id="HET3136150.1"
                     /translation="MNSRVEFRIFTIVDLDKKEEYLHEMHLKGWRYRTSRFGLFYFDQ
                     CQPDDVIYRIYDSRFLKKYKHELQDFRDRGWELIGAGSCSILRKSSSDLLPEDQVYMS
                     KGLKWEVMRSRLRSCTATFLGGLVVCTSLFREDLSMSFFLIFVLYAFLISYLIHGYFR
                     LKRKYRVDE"
     gene            7268..7568
                     /locus_tag="VQ865_001850"
                     /pseudo
     CDS             7268..7568
                     /locus_tag="VQ865_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818342.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit R"
     gene            7763..9601
                     /locus_tag="VQ865_001851"
     CDS             7763..9601
                     /locus_tag="VQ865_001851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000856786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HET3136151.1"
                     /translation="MKTPRYYQQIAINRTIETVARGQKRVMFVMATGTGKTFMAFQII
                     HRLRKAGLAKRVLFLADRNILVDQTMAEDFKPFEKVMTKITPKLLTAPEKLNSFEIYL
                     GLYQQLTGEDGTETHYQKFDKDFFDLIVIDEAHRGSAKENSNWRKIIDYFSSATQIGM
                     TATPKETKNASNTEYFGEPIYTYSLKQGIEDGFLAPYRVMRVNLDVDVDGYRPETGKV
                     DTNGQLIEDRYYGRKDFDKTIVIDDRTQRVAKFVSDYMKQSNARFDKTIVFCVDIDHA
                     ERMRAALVKENLDLVQEDYRYVMQVTGDNAEGKAQLDNFMDVNSNFPAIVTTSKLLTT
                     GVNAKTCRLIVLDSNIQSMTEFKQIIGRGTRLYPQKGKEFFTIIDFRNVTNLFADPDF
                     DGEPVKVLETGAKTVSGSTPGFVDEEGDPVEKYIVTDKQVTILNSTVQVLDENGKLIT
                     ESLTDYTRKNILGSYATLNDFITVWHTADKKKLILDELYKKGVYLDAIRESEGISEQE
                     IDDFDLLLKLAYGQKELTKTERINKLKQSGYLYKYSEEARAVLEILLNKYMDKGIGEL
                     ESIETLKLPEFQIYGGTFKIINTYFGDKKRYLQAIKELEQELFTVA"
     gene            9614..11077
                     /locus_tag="VQ865_001852"
     CDS             9614..11077
                     /locus_tag="VQ865_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000029054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SAM-dependent DNA methyltransferase"
                     /protein_id="HET3136152.1"
                     /translation="MSITSFVKRIQDITRNDAGVNGDAQRIEQMSWLLFLKIYDSREM
                     VWELEEDEYESIIPEELKWRNWAHAQNGERVLTGDELLDFVNNKLFKELKELEITSNM
                     PIRKTIVKSAFEDANNYMKNGVLLRQVINVIDEVDFNSPEDRHSFNDIYEKILKDIQN
                     AGNSGEFYTPRAATDFIAEVLDPKLGESMADLACGTGGFLTSTLNRLSSQRKTSEDTK
                     KYNTAVFGIEKKAFPHLLAVTNLFLHEIDDPKIVHGNTLEKNVREYTDDEKFDIIMMN
                     PPFGGSELETIKNNFPAELRSSETADLFMAVIMYRLKENGRVGVILPDGFLFGEGVKT
                     RLKQKLVDEFNLHTIIRLPHSVFAPYTGIHTNILFFDKTKKTEETWFYRLDMPDGYKN
                     FSKTKPMKSEHFNPVRDWWENREEILEGKFYKSKSFTPSELAELNYNLDQCGFPKEEE
                     EILNPFELIQNYQAERATLNHKIDNVLADILQLLEDK"
     gene            11077..>11266
                     /locus_tag="VQ865_001853"
     CDS             11077..>11266
                     /locus_tag="VQ865_001853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease"
                     /protein_id="HET3136153.1"
                     /translation="MTPEQLKASILQRAMEGKLVPQNPNDEPASELLKRIKAEKEKLI
                     SEGKIKRDKKETEIFRGDD"
BASE COUNT         3435 a         2207 c         2212 g         3412 t
ORIGIN      
        1 ccatggcaag ccgacgctga cgtggtttga agaaattttt gaagagtatc attcaccatt
       61 tcacaactaa atcgaagact ttctgccgta atgaaaacac ctgaaacagc ttggtttcag
      121 ctgtccggaa actttaagac ttaggttcaa agtttaggta tggaacttcg aaggaggtcg
      181 ctaccgtccg tcattactta ggaaagtctt aaaaaatcta taaagtaaaa agagcccgac
      241 agctcttttt gtttatactc aatgaaaatc aaaaagcaaa ctaggaaact agccacgggc
      301 tgctcaaaac actgttttga ggttgtagat acgactcaca tatatacggc aaggcaacgc
      361 tgacgtggtt tgaagagatt ttcgaagagt attattctcc atcaaaggca tcttttatat
      421 ggtcaaagaa gccttttttc tttggattta ctttcaagtc accagcagtc gcgaattctt
      481 tcaaggctac tttttggcgg tcgttcaagc ctgtcggtgt tacgacatta acagtaacgt
      541 attggtcacc aactgcaccg ccacgaaggc tcggtgcccc cttactacgt aggcggaatt
      601 tcttaccagt ctgagttccc tctggaataa ccaattcaac atcaccgtga acagttggaa
      661 tatctactgt atcaccaaga gccgcttgga caaagttgag gttgagattg tagaagatag
      721 tcgttccttc acgttcaaac ttgtcgctag cttctacaga aactactaca tacaagtcac
      781 cataaggtcc accgttaaag cctgcttcac cttgaccagc gaggcgaatt tgttgacctg
      841 tttccacacc agcagggatt ttcacatgta cgctatgagc ttgtttctca tgacctgttc
      901 catgacaggt tgtacatgga tatttgattt cttttcctcg accgtgacag acatcacagg
      961 ttacttggcg acgcatcata ccaagaggag tctgcgtatc gacgttaatg acaccagcgc
     1021 catgacagcg tccacaagtg actggacttg tccctggctt agcaccagag ccattacatg
     1081 tacgacagcc agcttcacga tgatacttaa cttccttctc agttccgaag atagcttctt
     1141 caaatgtcaa attgacacga tactggagat catctccttg gcgaggagcg tttggattgc
     1201 gcgaagaacc gcctccgccg aagaaacttg agaaaatatc ctcaaaacca ccgaagccac
     1261 ctgccccatt gaaaccaccg aaaccaccag ctccaccaaa accaccattg gcgcctgcag
     1321 caccatactg gtcataggca gcacgttttt ggtcgtcact caaagtctca taggcttctt
     1381 gaacttcctt gtacttgtcc tcagcaccag gctccttgtt gatatctggg tgatattttt
     1441 tggaaagctt acgataagcc tttttgatct cgtctgccga agcgtttttt gacaccccca
     1501 gacgatcata aaattcagta ttgttcatac aagataccaa gaccgtaaaa ttcgactgaa
     1561 aaataggaaa tctgacgctg gagcgacgct cctagacaga tttctctttt ttccgagaat
     1621 ttaggtcggg ttcaattcct ttcttttata ttgatgagat aatactccag ccactcggcc
     1681 ctatcccttt ttaccgaaaa acagaggctg ggttgcaacc tctgtggtta gattattcat
     1741 ttgaaataaa aatggttgta ttatctctag tagtaatctt caaagacctt ttagctaaat
     1801 caaactcaaa tttattatag tgtgggtctt gtgttttata taggtgtaac tcctgacata
     1861 tatgatccga aaagtaaatc ataacatctt taaacacaga agtgtagtca tatttactct
     1921 taccaacagc tacttctgta aattctttat aaatgacatt tccatttctt tccacagtca
     1981 ccagcatttc tgttggatta taatccaaat taaataattc ttcaaaaaac tttatctttt
     2041 catgataatc tgcaatgtca gaaagattat ttttattaac actcataaca ctagcccctt
     2101 atttttccgt aaactctccg tctacgacgt catcgcctgc gtttcctgtt gcttgtgcgc
     2161 cttctgctcc ttcttgagct tgttgcgctg ctgcggcttg ttcgtagagt ttaacagcaa
     2221 gtccttgagc tttttcgttc aatgcttcaa gtttcgcttt catgtcgtcc aagttgttgt
     2281 cttcttgagc tttcttaagg tcatcaaggg cagcttgggc agcgtcacgt tctgcgtcga
     2341 agcctttacc ttcagtttcc ttgattgtct tttcagtcgc aaagattgct tggtctactt
     2401 cattacgaag gtctacttct tctttacgtt tcttatcggc ttcagcgttt gcttctgcat
     2461 ctttcatcat gcggtcgatt tcttcgtcag tcaaacctga gttcgattgg atgacaatag
     2521 tttgttcttt ttgagttcca aggtctttgg ccttaacaga cacgataccg ttcttgtcga
     2581 tgtcaaatgt tacttcgatt tgaggaattc cacgaggtgc agctgggata tcagtcaatt
     2641 ggaagcgtcc aagagtcttg ttatctgctg ccattgggcg ttcaccttga agaacgtgga
     2701 tatcaacggc tggttggttg tctgctgctg ttgagaagac ttgtgattta gatgttggga
     2761 ttgtagtgtt gcgatcgata agttttgtaa atactccacc cattgtttcg ataccaagtg
     2821 acaatggcgt tacatcaaga aggacaacgt ccttgacatc accagtaatc acaccacctt
     2881 ggatagccgc acccatagca actacttcat cagggtttac tgatttgttt ggttctttac
     2941 cagtttcagc tttaacagct tcaacaacgg cagggatacg agttgaacca ccaacaagga
     3001 taacttcgtc gatttctgac aagctcaaac ctgcatctga aagggcttga cgaactggaa
     3061 cttttgtacg ttcaacaagg tcacgagtca aatcatcaaa tttcgcacga gtcaaagtca
     3121 tttccaagtg aagaggtcca gcctcacctg cagtgataaa tggcaagctg atttgtgttg
     3181 aagttacacc agaaaggtct ttcttcgctt tttcagccgc atctttcaaa cgttgcattg
     3241 ccatcttgtc agtagacaag tcgataccgt tttctttctt gaattctgct accaagtggt
     3301 caatgatttt ttggtcaaag tcgtcaccac caagtttgtt gtcccctgca gttgacaata
     3361 cgtcgaagac accgtcaccc aattcaagga tagagacgtc gaatgtacca ccaccaaggt
     3421 caaataccaa gattttttct tctttatcag tcttgtccaa accataagca agagctgctg
     3481 cagttggttc gttaacaata cgttctactt caagaccagc aattttacca gcgtcttttg
     3541 ttgcttgacg ttgagcgtcg ttgaagtaag ccggaactgt gataacagct ttggttactt
     3601 tctcaccaag gtagtcttca gcgtagcctt tcaagtattg aaggatcata gctgagattt
     3661 cttgtggagt gtattctttt ccatttgcag aaactttttc agaagttccc atcttagatt
     3721 tgatagagat aactgtatct gggtttgtga ctgcttgacg ttttgcagca tcaccaacga
     3781 tgatttctcc gtttttgaat gagactacag atggagttgt gcggtttcct tctgggtttg
     3841 cgatgatttt gctttcagtt ccttcaagaa ctgcaactgc tgagtttgtt gtacctaagt
     3901 caataccgat aattttagac atgtgttttt ctccttgtta gttaattttc tatttttctt
     3961 tttgatactc ttcttaagtg gcgacgccgt cagagcttga cttcgtcaat ctctttgact
     4021 aaactttgag cctaaggtct caaaatttgc gcaaatagcg ccacggcgaa gagtatcgtg
     4081 tttggttcgc ttcgctcact attacaaagc caaacatatt ttatctttct tcatagttta
     4141 ttgtcgtttc ggacaagttt tctattatgt aaattgcgac acgaagagtc gaaatcgatt
     4201 ttatttcgac gacgagttag taaggaagct aggcaaacgc catagcgatt gccgttttct
     4261 gacgagttgc tttagctacc gtcagaattg ccgaatcgaa cacgccctaa gctctgagta
     4321 aaaaagatag attttcttgt gttcatcgaa cacttcgtta atctcctatt tttactgcga
     4381 gctttttacg ggctttgtat cttagttata caccactacc attgctgggc gtaggatgcg
     4441 gtcatggagt ttgtagcctt tttgaaagac ttgagcgatg gtatctactg ggtgttcatc
     4501 gtctgctggg agagtttgga tggccatatg gtagttatgg tcaaattcgc catctgctgc
     4561 gatttcttca attccttctt ctttcaaagc gtgaatcaag ctttcttgca ccatccccaa
     4621 gcccttcttc acatcatctg tcaaaccttc aactgcaagt gcacgctcaa ggttgtcaag
     4681 agatggtaag attgcttttg ccaagtcctg gctacgataa cgttgcaagt tttgacgttc
     4741 ttcattggca cggcgttgga tattttgcat ttctgcatga gcgcgaagat atttgttttc
     4801 gaactcatct gcacgttcat ttgccaagtc caactcagac ttttcaggag ttgtttcttc
     4861 agctgtttcc acaacttcct cttcttgaac ttcttctact tcttcatttt ttatatcttg
     4921 ggccatgttc gcctccttta atgatttcaa tcttaatgta cttcgtaatg attactgctg
     4981 aggtagcggt aaaaatctgt caacttcatg gtcaaaacac ggttgaccac attgatttga
     5041 ttgattagct gttggtaatc cagattaact ggaccgataa tggctagaat tccaactccc
     5101 cgataaggaa tgaggaactt actactaatc accgctaggt cagctaaaca ggactcttga
     5161 ccgtctgcaa tacgaacatt ttgcatctga tcctcacgca acccctcacg aatctccaag
     5221 gccacctttt gcggttggtc aaagaactga taggctgcta gattggcaaa attcaagaga
     5281 ttgaccttgc ccgccatcac aatgttttcg ttgaacattt ccttaaagat gtgttcaaag
     5341 agatcgatga cattatccgt tgttgtaaag taacgctgga taatctgcgg aatctccgtc
     5401 cgaatcttgt agtgaatatc taaaacggtg tgaccgagga aacgttcctg aatgatgctc
     5461 ttcagtttca gcaaatcctc ctgcaagaag ttccttggaa tcagaaactg actagtaacc
     5521 gttcgcgact cgtctagggt aaataccgcc aaggctgtat gttgccccaa aacaacgata
     5581 tcaaaggctg tcaaacgttg cctgctcggc tcaacatcca gtgccactac cgtacagcca
     5641 ctcaggtctg ttagcaagtt agcagcctct tgcagaatat cctccaattt gaagaattcc
     5701 tgatcaaagg ctttgacaat ctcatatacc tcattttcag ccagccggtg aaaatccagt
     5761 gagtgtttca catagtactg aaaaccagca acacttggca tccgaccgct tgaagtatga
     5821 gccttctcaa gcaacccttg tttttctagt tccgccatgt cattacgaat ggttgcactg
     5881 ctagagttaa tagactcttg caaggctttt gatccgacag gttcgtgcgt tttggtaaag
     5941 atgtcaataa tcagatttaa aatatcctgc tgacgctctg taaccatctc atcactcctc
     6001 tctgtctgat caattagcac tcaatgcatc caagtgctaa cttatgattc tattatacac
     6061 ccttagaaga gaatgtcaag acaaaaactc aaaaaattag cactctttta tcaagagtgc
     6121 taaaaatcaa tctgaagacc tagaaccttg ctattcatct actcggtatt tcctttttag
     6181 tctgaaataa ccatgaatta gataagaaat cagaaaagca tataaaacaa aaataagaaa
     6241 gaaagacata gaaagatcct ctctaaacaa actcgtacaa acaacaagac cacctaagaa
     6301 agtagctgta caggaacgaa gtctagatcg cataacttcc catttgagcc ccttactcat
     6361 atagacttga tcctctggaa gtaaatcaga agacgattta cgaagaatcg aacaagaacc
     6421 tgctcctatc aattcccaac ctctatctct aaaatcttgc agttcatgct tatatttttt
     6481 aagaaatcta gaatcataga tacggtagat gacatcgtct ggttgacatt ggtcaaaata
     6541 gaacaaacca aaacgactcg ttctatacct ccaacctttc aaatgcatct catgtaaata
     6601 ttcttctttc ttgtccaaat caacaatggt gaaaatccga aattctactc tgctattcat
     6661 tgtcttaccc caaaattaga aaacatgcct agcgttattt attagataat tctttccact
     6721 tttgactcaa tctccaaaaa atataagaaa tctgaatcgc aaaaactatc aataaaaccc
     6781 aatctattat gaaaatcaaa aacacttccc aactgaaaga actacctcca gtgacaaact
     6841 ttgagaaaaa cggtagtaga gctaaaaaga gaagcaaaat aggaagcatc cgcattgtta
     6901 aaatccgttt ggcataaaaa aatctttatt taaacgaaaa tattatggca aaatttacgc
     6961 cagtttttga acggctgatg tagatatttt atactttcaa aatgtttaaa tgtgattatt
     7021 tatttttgaa aaatagctca ccagcccgac tgaaagtgct tatagaatga taataagtcg
     7081 cctgccgaaa acagcggaaa atagcggtgt tatgcggaga taatctgacg cgatgcgaaa
     7141 gtatattgca tacttatttt caacaattta gcagagtatt tttataagtg tgatataata
     7201 gaagtataat ttgttctgat agtttatttt atggagaagt agatttttag aatgcggagg
     7261 gttcaatatg gttgagttta taaagtctaa gaaagaaatg agtgaggagg atattaaagc
     7321 aaatttcatc actcctgcta ttgtatccaa aggatggaaa aatggtgagc atatcgctta
     7381 cgaagaatac ttcactgatg gtcgaattga ggttagagga gataaggctc gtcgtaaaga
     7441 aggaaaaaaa tcagactatt cactgtatta ccaatttgga actcgaattg caattgttga
     7501 ggcaaaggat aataaacaca gcgttcgagc aggattacaa caagctattg aatatggaga
     7561 gattttagat gttccatttg tttattcttc aaatggtgat ggctttattg aacacgaccg
     7621 tatcacgaga gaagaacgtg agctggagtt agacgaattc cctactcgtg aagaattatt
     7681 ttctcgtatg acgaaggaaa aaggattgac gtacgaaatt acagaagcta tctaaactcc
     7741 atactataca gacgccttct caatgaaaac gccacgctat tatcagcaaa tagctatcaa
     7801 ccgtactatt gaaacagttg ccagaggaca aaaacgagta atgtttgtga tggcaacagg
     7861 aacggggaaa acgttcatgg cttttcaaat tattcatcgc cttcgaaaag ctggtttggc
     7921 taaacgagtt ttattcttag cggatagaaa catcttagta gaccaaacga tggctgaaga
     7981 ctttaagcca ttcgaaaagg taatgacgaa aattacacca aaacttttga ctgctcctga
     8041 aaaattaaat tcttttgaaa tttatctagg gctttatcag caactaactg gtgaagatgg
     8101 aactgaaaca cattatcaaa aatttgacaa agacttcttt gatttaatcg taattgatga
     8161 agcgcaccgt ggttcagcta aggaaaacag taactggcgt aagataattg attatttcag
     8221 ttctgcgaca cagattggga tgaccgctac tcctaaagaa accaagaatg cttccaatac
     8281 ggaatacttt ggtgagccaa tctatactta tagtttaaaa cagggaatcg aggatggttt
     8341 tttggctcca tatcgtgtta tgagggttaa tttagatgtg gatgtggatg gttatcgtcc
     8401 agaaactgga aaagttgata ctaacggaca attaatagaa gataggtact acggcaggaa
     8461 agattttgat aaaaccattg tcattgatga tagaacgcaa agagttgcca agtttgtttc
     8521 tgattatatg aagcaaagca atgcacgatt tgataaaaca attgtttttt gtgttgatat
     8581 tgaccatgcc gagcgaatgc gtgctgcact tgtaaaagag aatctagact tagtccaaga
     8641 agactatcgt tatgtcatgc aagtaactgg tgacaacgct gaaggaaaag ctcaactgga
     8701 taactttatg gatgtcaatt ctaattttcc cgctattgta acaacgtcta aattattaac
     8761 gacaggagtt aatgctaaaa catgtcgttt gattgtttta gactctaata tccaatccat
     8821 gactgaattt aaacaaatta ttggtcgtgg cacacgtctt tatcctcaaa aggggaaaga
     8881 attttttacg attattgatt ttcgaaatgt taccaatttg tttgctgacc ctgattttga
     8941 tggtgagcca gtgaaggtgc tggaaacagg tgcgaaaaca gtcagtggtt ccacgcccgg
     9001 tttcgtagat gaggaaggtg acccagtaga aaaatatatc gttacagaca agcaggttac
     9061 cattcttaat tctactgttc aagtattgga tgaaaacggg aaactgatta ccgaaagcct
     9121 gaccgactac actcggaaga atatcttagg tagctacgcc actttgaacg attttatcac
     9181 agtttggcat acggcggata aaaagaagct tatcttagac gaactttata aaaaaggagt
     9241 ttatctagat gctattcgag agtcggaggg aatatcagaa caagaaatcg atgattttga
     9301 tttactccta aaacttgcct atggtcaaaa agaattaacc aaaacggaac gtatcaataa
     9361 actcaaacaa agcggatatt tatataaata tagtgaggaa gcgcgtgctg ttttggaaat
     9421 tttactgaac aaatacatgg ataaaggtat tggagaactc gaaagcattg aaacattaaa
     9481 acttccagaa tttcagatat atggtggaac cttcaaaatc atcaatactt attttggaga
     9541 taaaaaacga tatttacaag caattaaaga attggagcaa gagctattta cagtagctta
     9601 atgaaaggaa agtatgtcaa ttacatcatt tgtaaaaaga attcaagata tcactcgaaa
     9661 cgatgctggt gttaatggtg atgctcaacg tattgagcaa atgtcttggt tattattctt
     9721 aaaaatttat gatagccgtg aaatggtttg ggaattagaa gaagacgagt atgagtcaat
     9781 tatcccagag gaattaaaat ggcgaaattg ggctcatgct caaaatgggg aacgggtatt
     9841 gacaggcgat gaattacttg attttgtcaa taacaagtta ttcaaagagt tgaaagagct
     9901 tgaaataact tcaaatatgc ctattcgaaa aacgattgtt aaatcagctt ttgaagatgc
     9961 gaacaactat atgaaaaatg gcgtcttgtt acgccaagtc atcaatgtta ttgatgaagt
    10021 tgatttcaat agccctgaag atcgtcattc gtttaatgat atttacgaaa aaattcttaa
    10081 agatattcaa aatgctggga actcaggaga attttatacg ccacgtgcag cgactgattt
    10141 tattgccgaa gttcttgacc caaaacttgg agaatcaatg gcagaccttg cttgcggaac
    10201 aggaggcttc ttgacttcga ctctgaaccg tttaagtagt caacgtaaaa ctagtgaaga
    10261 taccaaaaaa tataatacag ctgtttttgg tattgaaaag aaagcatttc ctcatctttt
    10321 agcagttaca aatctgtttc ttcacgaaat tgatgaccct aaaattgttc atggaaatac
    10381 tttggagaaa aatgttcgtg aatatacgga tgatgaaaaa tttgacatta ttatgatgaa
    10441 tccacctttt ggagggtcag aattagaaac aataaaaaat aactttccag cagaattacg
    10501 gagttctgaa acagctgatt tatttatggc tgtcattatg tatcgtttga aagaaaatgg
    10561 tcgtgttgga gttattttac ctgatggttt tctatttggt gaaggtgtaa aaactcgctt
    10621 gaaacaaaaa ctggtagatg agttcaactt gcatacgatt attaggttgc ctcatagtgt
    10681 ctttgcaccg tatacaggaa tccatacgaa cattcttttc tttgataaaa caaagaaaac
    10741 agaagaaact tggttttatc gtttagatat gccagatggt tataaaaatt tctcgaaaac
    10801 taagccgatg aagtcagaac acttcaatcc tgttcgtgac tggtgggaaa atcgtgaaga
    10861 gattctggaa ggtaagttct acaaatctaa atcatttaca cctagtgaat tggctgagtt
    10921 gaattataat ttagaccagt gtggttttcc aaaagaggaa gaggaaatct taaatccctt
    10981 tgagttgatt cagaattatc aagcggaaag agcaacttta aatcataaga ttgataatgt
    11041 attagctgat attttgcagt tgttggagga caaataatga caccagaaca acttaaagca
    11101 agtattctcc aaagagcgat ggaagggaaa ttagtgccgc aaaatcccaa tgacgaacct
    11161 gcaagtgaat tattaaagag aattaaagct gaaaaagaaa aacttatcag tgaaggaaaa
    11221 atcaaacgag ataaaaagga aactgagata tttcgtggtg atgatg
//
LOCUS       DAVBOG010000060        11085 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.060, whole genome shotgun sequence.
ACCESSION   DAVBOG010000060 DAVBOG010000000
VERSION     DAVBOG010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11085
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.060"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..116
                     /locus_tag="VQ865_001854"
     CDS             <1..116
                     /locus_tag="VQ865_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3136154.1"
                     /translation="TPEQAKQILEYGVRGIVVGGAITRPKEITERFVAGLK"
     gene            140..1063
                     /locus_tag="VQ865_001855"
     CDS             140..1063
                     /locus_tag="VQ865_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000687303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclically-permuted mutarotase family protein"
                     /protein_id="HET3136155.1"
                     /translation="MKIDVINHLDSPGLAGMICRRINNRILVYGGSYFPNNDPLKSSK
                     VQSNKIRVYDGKFNLLFEQDGQISPDKGITIEVENEIYYILGSSIYRITIDESVEEIC
                     IGDFDFQLESGYGCYYNGHLFFGFQESYLFNIETKELFKKSDFPVSGRGQGLSVKYQN
                     ELYYLGGANNEAYLDGYKYIFEKDKWEKLEFELPSSVLGASSIQINESDLLILGGFNE
                     IAYNKAVIDLATPGYREEYFSKGRDFFNWNRSLRILDLETGKVDIIANDERFALCGAG
                     FLKTDNGYYVVSGECSPGRRTSDILLLEEEM"
     gene            1145..2773
                     /locus_tag="VQ865_001856"
     CDS             1145..2773
                     /locus_tag="VQ865_001856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HET3136156.1"
                     /translation="MKKIVKLALTAAAVLIAVVGLVACSSGSKKSDSSESGKEKVFYL
                     SGLLQGTGDRIPYVWQNGDGLVPYLLYRTLLMADSKYEKSTPDLAKDWKKSDDEKTYE
                     FTLKDGLKWSDGEALTASDVEFSVKLALKASVINGIFPSTFTKIEGAKDFKDDKADKI
                     SGLTVDGNKVTFKLTAPVGNFEQMMTQFFILPKHKLESENPLELNNSSFWTAPVTSGM
                     YKVKEISAGNFLEYDKNENYENEKPKFDKVVFNYISDPVLALQDGKSYFYSTNKPQEI
                     SQLDAVSTLTKKPIDILFYRYFIANLAGVEGNGDSLIANPKVREAILYAINRDELAKS
                     VFSGIADVNNTGVPSSLEAHLKSANKFEYNPEKAKQLLKEAKYDNSRNLILAYYYKDQ
                     ASQDFMQAVSYQLNEVGIKNEVVQITSDATTGLFKTRKYDLAYKGLSSFGYETWYGEY
                     SSTNTNFKNITNGETSFDELSKKLSETSDVKERNKILASLQKLEQEKLLKLNLFTFKN
                     FLYLNTEKVLIPDDVQFGNPFYKFDYKFEKWDAK"
     gene            2882..3832
                     /locus_tag="VQ865_001857"
     CDS             2882..3832
                     /locus_tag="VQ865_001857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136157.1"
                     /translation="MKKYILKKVLFMIPMLLIISFLVFIALDLTPADPLTYMVSPDMA
                     SSAEQIEKLRQQLGLNDPVLVRYGRWLWQLLHGDFGYSIVNGNPISKIVGQALPATFE
                     LAFVSLIISTIVGIVIGVISAVKQNGIIDNVARFLAVIGTAIPQFFFGILILNFFAIQ
                     LRILPIGGRFTSGDFTFINRVEHLILPVMAMSIALVAALMRYTRNSMLDVFNADYVKT
                     ARAKGVPEWKVYFKHIFRNAMRPILVLLIFRLPMLIGGSVIIESVFSWPGIGSIILSS
                     VTAGDYPVIMITTLMISVVVLFASLLVDIMAAILDPRIRY"
     gene            3849..4700
                     /locus_tag="VQ865_001858"
     CDS             3849..4700
                     /locus_tag="VQ865_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000803875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136158.1"
                     /translation="MKPMPLWKRNLKKFYNNKLAFIGFICFMLILLACILAPLLTTYS
                     PDVVDLGSMNRPPSAKHILGTDKLGRDVFARILYGGRVSIQVGMYGAICGAVIGTVLG
                     GIAGYFGGKIDALLVRLAELFLTFPNMIVILLLSSIFGQGVFNLIFVFSVMGWMTTFR
                     MVRNEFMSLKQETYVDVCRAFGFSDSRIIFNNILRNAISPVIVSLSLNVAGFILSEAG
                     LSFLGVGVPSDIPTWGNIINAAKTADVIKNSWWLWLVPGSIITLFVLSINFIGDGLRD
                     IMDPKQQ"
     gene            4713..6695
                     /locus_tag="VQ865_001859"
     CDS             4713..6695
                     /locus_tag="VQ865_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136159.1"
                     /translation="MNQTVLDVKNLKTEFITDKKAFPIIKDVNFTLERGKVLGIVGES
                     GCGKSVTVNTVLNLLPKNGRIAEGEITYFDEDKPIELQKLKQYGKEFRKLRGENISMI
                     FQDPMSALNPVYTIGNQITEVLHEHYDISKEEANKRAIEMLEKLGIHNAAERMNDYPH
                     QFSGGQRQRIVIAIAMVCNPDILIADEPTTALDVTIQAQILDLLDDLRKEHGTSIILI
                     THDLGVIAQIADEVAVMYAGEVVEVGTVAQIFDQPKHPYTRSLLRSIPNPENMDKKLH
                     VIQGSVPSISEISEKGCRFANRIPWLEKEHHEEEPQLHDLGDGHFVRCSCYKHFFFED
                     KEEETLAEKHVGNVVLEVKNIKKYYYPKKQLFKPLGSPLKALDDVSLELRKGTTIGIV
                     GESGSGKSTIAKSLMKLHEITDGEINIDLNGKTQNIYGIKRKEDLDFRKKVQMVFQDP
                     YASLNPTKKIYNSFDEPMIVHNIGNKEERFERMKESLKMVNVPVEYLERYPHEFSGGQ
                     RQRLCIARALCMKPEILILDEPVSALDLSVQAQVLNYLVEIQNKEDLTYVFISHDLGV
                     VKYMCDYLYVIHKGRIVEAGSREDIYNNPMHIYTKKLLAAIPEVDYHFKEALATKRKE
                     NEVEFKAQYHEFYDEDGRAYDLKQVSPTHFVALKPE"
     gene            6705..8114
                     /locus_tag="VQ865_001860"
     CDS             6705..8114
                     /locus_tag="VQ865_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000773463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136160.1"
                     /translation="MKLNKKIYFFDKGIFNPYRMSNVKLKVNQAVKDKEIFFTEEKPW
                     EIRFDNSYPNVFFDDLAGVYRCYYSTFTDDEESEKYSLEERKERQYLPRAKRIVSLCY
                     AESKDGVNWVKPNLGITEFRGSTENNIIGHFLHGTSVFLDKHDADENRRYKMFTKIDY
                     GNGVHFIAVAFSKDGLHFDEYIKVPNFNPRADTHNHIIYDEALNRYVLITRTWRDSLR
                     LPCVSTSADFINWTPIQEILNVCDYENQIYSMPIFKRGDYILGLASVFHEGDQLNKNY
                     DTVDLQLTYSYRHVGWHYLNTDTPLIPRGKGQYGDGEFDCGCIYSSAPVTIGDRTYFY
                     YMGGNGQHTNFRETSLSRAYIEKDHFAYWDIKRPEYPGVLYTNGFIFLNDQVYLDADI
                     AAGGFVTIELFENNHTPMEITASLEKIEDGRYQVLFSEPLPRTQTRLKISFKNAKIYA
                     IEGNLDIFRIESDNALLRG"
     gene            8119..8607
                     /locus_tag="VQ865_001861"
     CDS             8119..8607
                     /locus_tag="VQ865_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000872894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HET3136161.1"
                     /translation="MKYDLYDNCIELLKEREVTIEDMAALVIFSQQKYYPELTLDDAS
                     YAIQRVLKKREVQNVIMTGIELDKLAEAQKLSPEFQKIMEKDNPLYGIDEVIVLSILN
                     LYGSIAFTNYGYLDKLKPLILERLNENHEGVCNVFLDDIVGAIAAAACSKIAHNHASD
                     EI"
     gene            8895..9302
                     /locus_tag="VQ865_001862"
     CDS             8895..9302
                     /locus_tag="VQ865_001862"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HET3136162.1"
                     /translation="MTVINKFVLMEQAKKVLKNAYFPYSKFPVGAAILFKDGKVITGA
                     NIENVSFGVTNCAERSAIFYGTSQGYRKGDILAIAVAGETEDYLPPCNICRQVMVEFC
                     EPDTLVFLLNGKGNILELRLEELVPYSFSSLEM"
     gene            9334..10251
                     /locus_tag="VQ865_001863"
     CDS             9334..10251
                     /locus_tag="VQ865_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002894436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HET3136163.1"
                     /translation="MSDLKKYEGVIPAFYACYDDQGEVSPERTRALVQYFIDKDVQGL
                     YVNGSSGECIYQSVEDRKLILEEVMAVAKGKLTIIAHVACNNTKDSMELARHAESLGV
                     DAIATIPPIYFRLPEYSVAKYWNDISSAAPNTDYVIYNIPQLAGVALTPSLYTEMLKN
                     PRVIGVKNSSMPVQDIQTFVSLGGEDHIVFNGPDEQFLGGRLMGARAGIGGTYGAMPE
                     LFLKLNQLIADKDLETARELQYAINAIIGKLTSAHGNMYGVIKEVLKINEDLNIGSVR
                     SPLTPVTEEDRPVVEEAAALIRETKERFL"
     gene            10278..10472
                     /locus_tag="VQ865_001864"
                     /pseudo
     CDS             10278..10472
                     /locus_tag="VQ865_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398633.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
     gene            complement(10622..>11085)
                     /locus_tag="VQ865_001865"
     CDS             complement(10622..>11085)
                     /locus_tag="VQ865_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000547411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3136164.1"
                     /translation="YAMFDKEQKRGYKQSARNLANWHYNDKEDSYTHPDGWYYRFHHT
                     KYQKTQTDFQQKIKVYYADEPESAPQKGLYMNERYQNLKAKECQALLSPQGRQIFAQR
                     KIDVEPVFGQIKACLGYKRCNLRGKRQVRIDMRLVLMANNLLKYNKRTTQN"
BASE COUNT         3693 a         1665 c         2115 g         3612 t
ORIGIN      
        1 atacaccaga acaagccaaa caaatccttg aatatggagt gcgaggaatc gttgttggtg
       61 gcgctattac tagaccaaaa gagattacag aacgttttgt agcgggatta aaatagcatg
      121 ccagagtaag aggtgtaata tgaaaattga tgttataaat catttagact caccaggatt
      181 agctgggatg atttgtagac ggattaataa tagaatttta gtttatggag gtagttattt
      241 cccaaataac gatcctttaa aaagttcaaa agttcaatca aataaaatta gagtttatga
      301 cgggaaattt aatcttctat ttgaacaaga tggacagatt tctccagata aaggaataac
      361 gattgaagtt gaaaatgaaa tctattacat tctaggctcg agcatttatc gtattacgat
      421 tgatgaaagt gtagaagaaa tctgtatcgg ggattttgat ttccaactag agagtggtta
      481 tggttgttat tataatggcc acttattctt tggatttcag gaaagttatc tgttcaatat
      541 tgagactaaa gaacttttta aaaaatctga cttcccagtt tctggtagag gacaaggttt
      601 atcagtcaaa tatcaaaatg aattgtatta tttaggtgga gcgaacaatg aagcttattt
      661 agatggatac aaatatattt ttgaaaaaga taagtgggaa aaacttgagt ttgaattacc
      721 aagttcagtt ttaggagcgt caagtataca aataaatgaa agtgatttat taatccttgg
      781 tggctttaat gaaattgctt ataataaagc agttattgat ttagcaaccc ctggctatag
      841 ggaagaatac ttttctaagg gaagagattt ctttaattgg aatcgtagct tgcgaatact
      901 agatttagag acaggtaagg tcgatattat tgcaaacgat gagcgttttg ctctttgtgg
      961 ggcaggattt ttaaaaactg ataatggata ttacgttgtt agtggggaat gtagcccagg
     1021 aagacgtact tctgacatac ttttgttaga ggaggaaatg taacgaagag tttaaatttt
     1081 taattactgc aatacttact taatcacata aataattact taatacaaat aaaggagtat
     1141 taaaatgaaa aaaattgtta aattagcttt aacagctgca gcagttttaa tagctgtagt
     1201 aggattggtt gcttgtagtt cgggaagcaa aaaatctgat tcttcagagt ctggaaaaga
     1261 aaaagtattc tatttatcag gtttgcttca aggaactgga gatcgtatcc cttacgtttg
     1321 gcaaaatggt gatggtttag ttccatattt gttataccgt acactgttaa tggcagattc
     1381 aaaatatgaa aaatcaactc cagatttagc taaagattgg aaaaaatctg atgatgaaaa
     1441 aacttatgaa tttacactta aagatgggtt gaaatggtct gatggagaag ctttgacagc
     1501 ttccgatgtg gaattcagtg ttaaattagc attgaaagct tcagtaatta atggaatttt
     1561 cccttcaaca ttcacaaaaa ttgaaggagc taaagatttc aaagacgata aagcagataa
     1621 aatttctggt cttacagttg atggaaataa agtaacattt aaacttactg ctccagttgg
     1681 taactttgag caaatgatga ctcaattctt tattcttcca aaacataaat tagagtctga
     1741 aaatcctctt gaattaaata atagctcatt ttggacagct cctgttacaa gcggtatgta
     1801 caaagtaaaa gaaattagtg caggtaattt cttagagtat gacaaaaatg aaaactatga
     1861 aaatgaaaaa ccaaaatttg ataaagtagt attcaactat atttcagatc cagttttagc
     1921 attgcaagat ggtaaatcat acttctattc aacaaacaaa cctcaagaaa ttagtcagtt
     1981 ggatgctgta tctactttaa ctaaaaaacc aattgatata ctattctatc gctactttat
     2041 cgctaactta gcaggtgttg aaggtaatgg agattccttg attgctaatc ctaaagttag
     2101 agaagctatt ctatatgcaa ttaatcgtga tgaattagct aaatctgtat ttagtggaat
     2161 tgcagatgtt aataatactg gtgttccttc aagcttagaa gctcatctga aatcagcaaa
     2221 taaatttgaa tataatccag aaaaagcaaa acaacttctt aaagaagcta aatacgataa
     2281 tagcagaaat ctaattttag cttattacta taaagatcaa gcctctcaag atttcatgca
     2341 agcagtaagt tatcaattga atgaggttgg aatcaagaac gaagttgtcc aaattacttc
     2401 tgatgcaaca acaggattgt tcaaaacacg taaatatgac ctagcttata aaggattatc
     2461 atcatttggt tatgaaactt ggtatggtga atatagttca acaaatacta actttaaaaa
     2521 tattacaaat ggcgaaacaa gttttgatga gttgagcaaa aaattgtctg aaacttctga
     2581 tgtaaaagaa agaaacaaaa ttttagcaag tctacaaaaa ttagaacaag aaaaactatt
     2641 gaagttaaac ttattcacat ttaaaaactt cttgtattta aatactgaaa aagttttaat
     2701 tcctgacgat gttcaatttg gtaatccatt ctataaattt gattacaaat tcgaaaaatg
     2761 ggatgctaaa taaaatcgtt taaaattatc agtgattaag tttgataatc ttttaggagt
     2821 gtagagatgc tgtttattga atcatgtatc tctcactctt gttttttcag gagaaattaa
     2881 aatgaaaaaa tatattctaa aaaaagtatt attcatgatt cctatgttgt tgattattag
     2941 ctttttagta ttcattgcac tagatttaac accagcagat ccattgacat atatggtatc
     3001 tccagatatg gctagtagtg cagaacaaat cgaaaagcta agacagcaat taggtttaaa
     3061 tgatccagta ttagttcgct atggaagatg gctttggcaa ttactccatg gtgattttgg
     3121 atacagtatt gtaaatggta acccaatttc caaaattgta ggacaagcat tgcctgcaac
     3181 ttttgaatta gcttttgtgt cattaattat ttcaacaatt gttggtattg taattggggt
     3241 tatatcagcc gttaaacaaa atggtattat cgataatgtt gctcgttttc tagctgttat
     3301 cggaactgcg attccacaat ttttctttgg tattttaatt ttaaacttct ttgcaattca
     3361 gttaagaatt ttacctattg gtggtagatt taccagtgga gattttacat ttattaatag
     3421 agttgaacac ttaattctac cagtaatggc tatgtcaatt gcattggtag ccgctttaat
     3481 gagatacaca cgtaattcta tgttggatgt ttttaatgca gattatgtta aaacagctcg
     3541 tgcaaaaggt gttcctgaat ggaaagttta ttttaaacac atatttagaa atgctatgcg
     3601 accaatttta gtgttattga ttttccgtct accaatgtta attggtggat cagtaattat
     3661 cgagagtgtc ttttcttggc ctggaattgg ttctatcatc ctatctagtg taacagcagg
     3721 tgactatcct gtaattatga ttaccacatt aatgatttct gtcgtagtgt tatttgctag
     3781 tctacttgta gatattatgg ctgcaatatt agacccacgt attcgttatt aggaaggagg
     3841 tcaatgttat gaaacctatg cctttatgga aaagaaattt gaaaaaattc tataataaca
     3901 aattggcctt tatcggcttt atatgcttca tgctaattct attagcatgt attctagcac
     3961 ctttattgac aacctattct ccagatgttg ttgatttagg atctatgaac cgtcctcctt
     4021 cagcaaaaca cattctggga acagataaac taggtcgtga cgtatttgct cgaatcctat
     4081 atggtggtcg agtttcaatt caagtaggga tgtatggagc gatttgtgga gcggttattg
     4141 gtactgtact tggtggtatt gctggatatt ttggtgggaa aattgatgct cttctagttc
     4201 gtctagcaga attattctta acattcccga atatgattgt cattctcttg ctttcaagta
     4261 tttttggaca aggtgtattc aatcttatct tcgtattctc agtaatgggt tggatgacaa
     4321 cgttccgaat ggttcgtaat gagttcatgt ctttgaaaca agaaacatat gtggatgtat
     4381 gtagagcttt tggtttttct gacagtcgaa ttatctttaa taatatttta agaaatgcta
     4441 tctcaccagt aattgtatcg ttgtctttaa acgttgctgg tttcattctc agtgaggcag
     4501 gtcttagttt cttaggagta ggtgttcctt ctgatattcc tacttgggga aatatcataa
     4561 atgctgccaa aacagccgat gttattaaaa atagttggtg gctgtggtta gttccagggt
     4621 caatcattac tcttttcgtt ctttctatca actttattgg tgatggatta cgagatataa
     4681 tggatccgaa acaacagtag gaggttgaca aaatgaatca aacagtttta gatgtaaaaa
     4741 acttaaaaac tgaattcatc actgataaaa aagcatttcc gattattaaa gatgtaaact
     4801 tcactttgga aagagggaaa gttttaggga ttgttggtga atctggatgc ggtaagagtg
     4861 taacagtgaa tacagtgtta aacttattac ctaaaaatgg acgcattgct gaaggtgaaa
     4921 tcacatattt cgatgaagat aagccgatag agcttcaaaa attaaagcaa tatggtaaag
     4981 aatttcgaaa gttacgtggt gaaaacatat caatgatttt ccaagatcca atgtctgcat
     5041 tgaatccagt atatacaatt ggtaatcaaa ttactgaagt ccttcatgaa cattatgaca
     5101 tttctaaaga ggaggcaaat aaacgtgcta tagaaatgtt agaaaaactt ggaattcata
     5161 atgctgcaga acgcatgaat gactatccac accaatttag tggagggcag cgtcaaagaa
     5221 tagtcatagc gattgcaatg gtatgtaatc cagatattct aattgcagat gaaccaacaa
     5281 ctgcccttga tgtaacaatc caagcacaaa tacttgattt acttgatgat ttacgtaaag
     5341 agcatggaac ttctattatc ttaattactc acgatttagg cgttattgct caaattgcgg
     5401 atgaagttgc agtgatgtat gctggtgaag tcgttgaagt tggaactgta gctcagatct
     5461 ttgatcaacc taaacacccg tatactcgtt ctctattaag atctattcct aatcctgaaa
     5521 atatggataa aaagctacat gttatccagg ggagcgtacc ttcaatttct gaaatatctg
     5581 aaaaaggatg cagattcgca aatcgtattc catggttaga aaaagaacat catgaagaag
     5641 aacctcaatt gcatgattta ggtgacggac attttgtaag gtgttcttgc tataaacatt
     5701 tctttttcga agataaggaa gaagaaacat tagcggaaaa acatgtaggt aatgttgttt
     5761 tagaagtaaa aaatattaaa aagtactact atcctaagaa acaactattc aagccactag
     5821 gttctccgtt gaaagcactt gatgacgtat ctctagagtt aagaaaagga actactattg
     5881 gtatcgtagg agagtctgga agcggtaaga gtacgattgc gaaatcatta atgaaactcc
     5941 atgagattac agatggtgaa atcaatattg atttgaatgg gaaaactcaa aatatttatg
     6001 gaattaaacg taaggaagat ttggatttcc gtaagaaagt tcaaatggta ttccaagatc
     6061 cttatgcatc attgaaccca actaagaaaa tttataattc atttgatgaa ccgatgattg
     6121 tccataatat tggaaacaaa gaggaacgct ttgaacgtat gaaagaatcc ttgaagatgg
     6181 taaacgtgcc agttgagtac ttggagcgtt atcctcatga attttcaggc ggacaacgtc
     6241 aacgtttatg tattgctcgt gccctttgta tgaaaccaga aattttaatt ttagatgaac
     6301 ctgtttcagc attagatcta tctgtacaag cgcaagtttt gaattatctt gttgaaatcc
     6361 aaaataaaga agatttgact tatgtattta tttctcatga cctaggtgtt gtgaaataca
     6421 tgtgtgacta tctatatgtt attcataaag gacgtattgt agaagctggt tctcgagaag
     6481 atatctacaa taacccaatg catatttaca ctaaaaaact attagctgct attccagaag
     6541 ttgattatca cttcaaagag gcattggcaa caaaacgtaa agaaaatgaa gttgaattta
     6601 aagcacagta ccatgaattt tatgatgaag atggccgtgc ttatgatctt aagcaggttt
     6661 caccaacaca ttttgtagcg ttaaaaccag aataggtggt aaatatgaaa ttaaataaaa
     6721 aaatatattt ctttgataaa ggaattttta atccttatcg aatgagtaat gtaaaattaa
     6781 aagttaatca ggcagtaaag gataaagaaa ttttcttcac tgaggaaaaa ccatgggaaa
     6841 ttcgttttga taacagttat ccaaatgttt tctttgatga tttagcaggt gtttatcgtt
     6901 gctactattc tacatttact gatgatgagg agtctgaaaa atactcttta gaggagcgta
     6961 aggaacgtca atatctacct cgtgcgaagc gtattgtttc actttgttat gctgaaagta
     7021 aagatggtgt taactgggtg aaaccaaatc taggtattac agaatttcga ggatcaactg
     7081 aaaataatat tatcggacat tttttacatg gtacatctgt ttttctagat aaacatgacg
     7141 cagatgaaaa tcgtcgttat aaaatgttta caaagattga ttacggtaac ggtgttcatt
     7201 ttattgctgt agcattttca aaagatggtc tacactttga tgaatacatt aaagtaccaa
     7261 acttcaatcc acgtgcagac actcataacc atatcatata tgatgaagca ttaaatcgct
     7321 atgtgctaat tactcgtact tggagagatt cattgcgctt gccgtgtgta tctacgagtg
     7381 ctgatttcat taactggact ccaattcaag aaattttgaa tgtctgtgat tatgaaaatc
     7441 aaatttattc tatgcctatt tttaaacgtg gcgattatat actaggttta gcttcagttt
     7501 tccatgaagg agatcaactg aacaagaatt acgatacagt ggaccttcaa ttgacttata
     7561 gttatcgtca tgttggttgg cattatctaa acactgatac tccacttatt cctcgtggta
     7621 aaggtcaata tggtgatgga gaatttgact gtggatgtat ctattcttct gcaccagtta
     7681 ctatcggtga ccgtacttat ttctactaca tgggaggaaa tggacaacat acaaacttcc
     7741 gtgaaacaag cttgtctcgt gcttatattg agaaagatca ctttgcatat tgggatatta
     7801 aacgtccaga atatccaggt gttttgtata ccaatggatt tattttcctc aatgatcaag
     7861 tttaccttga tgcagatatt gcagctggag gctttgtaac aattgaattg ttcgagaata
     7921 atcacactcc aatggaaatt acagcttccc ttgaaaaaat agaagatggt cgctatcaag
     7981 tgttattcag cgaaccttta cctcgaactc aaactcgact gaaaattagc tttaaaaatg
     8041 ctaaaatcta cgcaatcgaa ggaaatttag atattttcag aattgaatca gacaatgctc
     8101 tattgagggg gtaagattat gaaatatgat ttatatgata attgtattga acttctaaaa
     8161 gaacgcgaag ttacaattga agatatggca gcgttagtaa tattttcaca acaaaaatat
     8221 taccctgaat taactcttga cgacgcttca tatgcaattc aacgtgtact aaaaaaacgt
     8281 gaagttcaga atgtaattat gacaggaatt gagttagata agttagctga agcacaaaaa
     8341 ctatctccag aatttcaaaa gattatggag aaagataatc cattgtatgg gattgatgaa
     8401 gtaatcgtct tatcgatatt gaatttatat ggttctattg cctttacaaa ttatggctat
     8461 ttagataaat taaaaccact gattttagaa agattgaatg agaatcacga aggtgtttgt
     8521 aatgtatttc tagatgatat tgttggtgca atagccgcag cagcatgtag taaaattgca
     8581 cacaatcatg ctagtgatga aatataacta ttgaatttag tatcgtaaat aataaagcgt
     8641 ttggtttcta gattattgtc attcaaattg gataatgata aatctagaaa ccaaatatat
     8701 tttccgcata aaatgaggga ttatatatct cactttttta caattgtata gtggattaaa
     8761 actagaatag tgcatctcta cttctaaaac attgttagaa atcgatttga ctgtcctgat
     8821 tgatttgtac tgttcttatt tcattttact ataatttagt gtgagtaaaa tataataata
     8881 aaggagttaa aacaatgaca gtaattaata aatttgtttt aatggagcaa gcaaaaaaag
     8941 ttttaaaaaa tgcttacttt ccgtattcca aatttcctgt aggtgcagca attttattta
     9001 aagatggtaa agtaattaca ggagcaaata tagaaaatgt atcgtttggt gtaactaact
     9061 gtgcagaacg tagtgctatt ttttatggga cttctcaagg atatagaaaa ggagatattc
     9121 ttgcgattgc tgttgcaggt gaaactgaag actacttacc accatgcaac atttgtcgtc
     9181 aagttatggt agaattttgt gagcctgata ccttagtctt tctattaaat ggtaagggaa
     9241 acatacttga attgcgatta gaggaattag tcccatattc gttctcaagt ctagaaatgt
     9301 aattacgtag tatgaaataa ggagaaaaaa acaatgtcag atttgaaaaa atacgaaggt
     9361 gtcattccag ccttctacgc atgttatgat gatcaaggag aagtaagccc agaacgtacg
     9421 cgtgccttgg ttcaatactt cattgataaa gatgttcaag gtctttatgt caatggttct
     9481 tctggtgaat gtatctacca aagcgttgaa gatcgcaagt tgattttgga agaagtcatg
     9541 gcggtagcca aaggtaaatt gaccattatt gcccatgttg cttgcaataa tactaaagac
     9601 agtatggaac ttgctcgcca tgctgaaagc ttgggagtag atgctattgc aacgattcca
     9661 ccaatttatt tccgcttgcc agaatactca gttgccaaat actggaacga tatcagttct
     9721 gcagctccaa acacagacta cgttatttac aacattcctc aattggcagg ggttgctttg
     9781 actccaagcc tttacacaga aatgttgaaa aatcctcgtg ttatcggtgt gaagaactct
     9841 tctatgccag ttcaagatat ccaaaccttt gtcagccttg gtggagaaga ccatatcgtc
     9901 tttaatggtc ctgatgagca gttcctagga ggacgcctca tgggggctag ggctggtatc
     9961 ggtggtactt atggtgctat gccagaactc ttcttgaaac tcaatcagtt gattgcggat
    10021 aaggacctag aaacagcgcg tgaattgcag tatgctatca acgcaatcat tggtaaactc
    10081 acttctgctc atggaaatat gtacggtgtc atcaaagaag ttttgaagat caatgaagac
    10141 ttgaatattg gatctgttcg ttcaccattg acaccagtga ctgaagaaga tcgtccagtt
    10201 gtagaagaag ctgctgcctt gattcgtgaa accaaggagc gcttcctcta atccataagg
    10261 aggtatttat gacgcactac gttgccaatc cagaggtggt cattctcggg ggtggcatca
    10321 tgggacaaga agctatcctc aaaccaaaga ttcgtgcagc cttgaaagaa gccttggttc
    10381 caagtttggc tgagaacaca agattagaat ttgctcatca tcaaaacact gctgatatgc
    10441 ttggagccta ctatcatttt aaaataaaat aaatttaata tttactttac taaattagtg
    10501 tattcttcct actttaatta gagaatgatt taagttctct ttaaaaatca aaagagtcta
    10561 ggataaaata gttctcaatc acaaaaaagc taaagatttc caattgtgga actctagctt
    10621 tttaattttg agtcgttctc ttattgtatt ttaggaggtt attggccata agtaccaatc
    10681 tcatgtcaat tctcacttga cgcttccctc tcagattaca tctcttgtaa cccaaacaag
    10741 cctttatctg cccaaagaca ggttccacat caatcttgcg ttgagcgaaa atctgtctac
    10801 cttggggaga taaaagcgcc tgacattctt tagctttcaa gttttgatag cgttcgttca
    10861 tatacagtcc cttttgaggg gctgattcag gttcgtcggc gtagtaaacc ttgatttttt
    10921 gttgaaagtc tgtctgtgtt ttctgatatt tggtatggtg aaaacgataa taccagccat
    10981 caggatgtgt atagctatcc tccttgtcat tatagtgcca attcgctaag tttctagctg
    11041 actgtttata gcctctcttt tgttccttat caaacatggc atatt
//
LOCUS       DAVBOG010000061        11007 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.061, whole genome shotgun sequence.
ACCESSION   DAVBOG010000061 DAVBOG010000000
VERSION     DAVBOG010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 11007)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11007)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11007
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.061"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(128..1759)
                     /locus_tag="VQ865_001866"
     CDS             complement(128..1759)
                     /locus_tag="VQ865_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004251733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HET3136165.1"
                     /translation="MSINWQEILFHFLGGLGLFLYSIKTMGDGLQQAAGDRLRFYIDK
                     YTSNPFFGVLVGIGMTALIQSSSGVTVITVGLVSAGLLTLRQAIGIVMGANIGTTVTS
                     FLIGFKLGNYALPMLFIGAVCLFFTKNRTVNNIGRILFGVGGIFFALNLMSGAMAPLK
                     DLQVFKDYMIELSKNPVLGVFVGTGLTLLIQASSATIGILQNLYAGNLIDLQGALPVL
                     FGDNIGTTITAIIASLGANIAAKRVAGAHVAFNVIGTVVCVIFLVPFTVLIHWFEATL
                     NLAPEMTIAFAHGTFNITNTIVQFPFIGALAYFVTKIIPGEDEVVKYEPLYLDEHFIK
                     QAPSIALGNAKKELLHLGNYAAKAFDLSYKYIIDLDEKVAEKGHKTEEAINTIDEQLT
                     RYLIALSSEALSQKESEVLTNILDSSRDLERIGDHTEALLNLTDYLQRKNVEFSDAAL
                     KELEEVYRQTSDFIKDALDSVENNDIEKARSLVERHEAINKIERVLRKTHIKRLNKGE
                     CSTQAGVNFIDIISHYTRVSDHAMNLAEKVFAEQI"
     gene            2052..6992
                     /locus_tag="VQ865_001867"
     CDS             2052..6992
                     /locus_tag="VQ865_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000795197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HET3136166.1"
                     /translation="MKNPFFERRCRYSIRKLSVGACSLMIGAVLFVGPALAEETAVPE
                     NSGANTELVSGESEHSTNEADKQNEGEHTRENKLEKAEGVATASETAEAASAAKPEEK
                     AGEVVAETPSAEAKPKSDKETEAKPEATNQGDESKPAAEANKTEKEVQPDVPKNTEKT
                     LKPKEIKFNSWEELLKWEPGAREDDAINRGSVVLASRRTGHLVNEKASKEAKVQALSN
                     TNSKAKDHASVGGEEFKAYAFDYWQYLDSMVFWEGLVPTPDVIDAGHRNGVPVYGTLF
                     FNWSNSIADQERFAEALKQDADGSFPIARKLVDMAKYYGYDGYFINQETTGDLVKPLG
                     EKMRQFMLYSKEYAAKVNHPIKYSWYDAMTYNYGRYHQDGLGEYNYQFMQPEGDKVPA
                     DNFFANFNWDKAKNDYTIATANWIGRNPYDVFAGLELQQGGSYKTKVKWNDILDENGK
                     LRLSLGLFAPDTITSLGKTGEDYHKNEDIFFTGYQGDPTGQKPGDKDWYGIANLVADR
                     TPAVGNTFTTSFNTGHGKKWFVDGKVSKDSEWNYRSVSGVLPTWRWWQTSTGEKLRAE
                     YDFTDAYNGGNSLKFSGDVAGKTDQDVRLYSTKLEVTEKTKLRVAHKGGKGSKVYMAF
                     STTPDYKFDDADAWKELTLSDNWTNEEFDLSSLAGKTIYAVKLFFEHEGAVKDYQFNL
                     GQLTISDNHQEPQSPTSFSVVKQSLKNAQEAEAVVQFKGNKDADFYEVYEKDGDSWKL
                     LTGSSSTTIYLPKVSRSASAQGTTQELKVVAVGKNGVRSEAATTTFDWGMTVKDTSLP
                     KPLAENIVPGATVIDSTFPKTEGGEGIEGMLNGTITSLSDKWSSAQLSGSVDIRLTKP
                     RTVVRWVMDHAGAGGESVNDGLMNTKDFDLYYKDADGEWKLAKEVRGNKAHVTDITLD
                     KPITAQDWRLNVVTSDNGTPWKAIRIYNWKMYEKLDTESVNIPMAKAAARSLGNNKVQ
                     VGFADVQAGATITVYDNPNSQTPLATLKSEVGGDLASAPLDLTNQSGLLYYRTQLPGK
                     EISNVLAVSVPKDDRRIKSVSLETGPKKTSYAEGEDLDLRGGVLRVQYEGGTEDELIR
                     LTHAGVSVSGFDTHHKGEQNLTLQYLGQPVNANLSVTVTGQDEASPKTILGIEVSQKP
                     KKDYLVGDSLDLSEGRFAVAYSNDTMEEHSFTDEGVEISGYDAQKTGRQTLTLRYQGH
                     EVNFDVLVSPKAALNDEYLKQKLAEVEAAKNKVVYNFASPEVKEAFLKAIEAAEQVLK
                     DHEISTQDQVNDRLNKLTEAHKALNGQEKFKEEKTELDRLTGEVQELLDAKPNHPSGS
                     ALAPLLEKNKVLVEKVDLSPEELATAKQSLKDLVALLKEDKPAVFSDSKTGVEVHFSN
                     KEKTVIKGLKVERVQASAEEKKYFAGEDAHVFEIEGLDEKGQDVDLSYASIVKIPIEK
                     DKKVKKVFFLPEGKEAVELAFEQTDSHVIFTAPHFTHYAFVYESAEKPQPAKPAPQNK
                     VLPKPTYQPASDQQKAPKLEVQEEKVAFHRQEHENAEMLVGEQRVIIQGRDGLLRHVF
                     EVDENGQRRLRSTEVIQEAIPEIVEIGTKVKTVPAVVATQEKPAQNTAVKSEEASKQL
                     PNTGTADANEALIAGLASLGLASLALTLRRKREDKD"
     gene            7082..8278
                     /locus_tag="VQ865_001868"
     CDS             7082..8278
                     /locus_tag="VQ865_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HET3136167.1"
                     /translation="MAKLTVKDVDLKGKKVLVRVDFNVPLKDGVITNDNRITAALPTI
                     KYIIEQGGRAILFSHLGRVKEEADKAGKSLAPVAADLAAKLGQDVVFPGVTRGAELEA
                     AINALEDGQVLLVENTRYEDVDGKKESKNDPELGKYWASLGDGIFVNDAFGTAHRAHA
                     SNVGISANVEKAVAGFLLENEIAYIQEAVETPERPFVAILGGSKVSDKIGVIENLLEK
                     ADKVLIGGGMTYTFYKAQGIEIGNSLVEEDKLDVAKALLEKANGKLILPVDSKEANAF
                     AGYTEVRDTEGEAVSEGFLGLDIGPKSIAKFDEALTGAKTVVWNGPMGVFENPDFQAG
                     TIGVMDAIVKQPGVKSIIGGGDSAAAAINLGRADKFSWISTGGGASMELLEGKVLPGL
                     AALTEK"
     gene            8414..8941
                     /locus_tag="VQ865_001869"
     CDS             8414..8941
                     /locus_tag="VQ865_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HET3136168.1"
                     /translation="MSYFKKYKFDKSQFKLGMRTFKTGIAVFLVLLIFGFFGWKGLQI
                     GALTAVFSLRESFDESVHFGTSRILGNSIGGLYALVFFLLNTFFHEAFWVTLVVVPIC
                     TMLTIMTNVAMNNKAGVIGGVAAMLIITLSIPSGETISYVFVRVSETFMGVFVAIIVN
                     YDIDRIRLFLEKKEK"
     gene            9018..9374
                     /gene="glnR"
                     /locus_tag="VQ865_001870"
     CDS             9018..9374
                     /gene="glnR"
                     /locus_tag="VQ865_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000659547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor GlnR"
                     /protein_id="HET3136169.1"
                     /translation="MKEKEFRRNMAVFPIGSVMKLTDLSARQIRYYEDQELIKPDRNE
                     GNRRMYSLNDMDRLLEIKDYISEGYNIAAIKKKYAEREAKSKKAVSQTEVRRALHNEL
                     LQQGRFASVQSPFGRG"
     gene            9411..10757
                     /gene="glnA"
                     /locus_tag="VQ865_001871"
     CDS             9411..10757
                     /gene="glnA"
                     /locus_tag="VQ865_001871"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HET3136170.1"
                     /translation="MPITAADIRREVKEKNVTFIRLMFSDILGTMKNVEIPATDEQLD
                     KVLSNKVMFDGSSIEGFVRINESDMYLYPDLDTWTVFPWGDENGSVAGLICDVYTTEG
                     EPFAGDPRGNLKRALRHMEEVGFKSFNLGPEPEFFLFKLDENGDPTLEVNDKGGYFDL
                     APTDLADNTRREIVNVLTKMGFEVEASHHEVAVGQHEIDFKYDEVLRACDKIQIFKLV
                     VKTIARKHGLYATFMAKPKFGIAGSGMHCNMSLFDAEGNNAFFDPNDPKGMQLSETAY
                     HFLGGLIKHAYNYTAIMNPTVNSYKRLVPGYEAPVYIAWAGRNRSPLVRVPASRGMGT
                     RLELRSVDPMANPYIAMAVLLEVGLYGIENKIEAPAPIEENIYIMTAEERKEAGITDL
                     PSTLHNALKALTEDEVVKAALGDHIYTSFLEAKRIEWASYATFVSQWEIDNYLDLY"
     gene            complement(10847..10966)
                     /locus_tag="VQ865_001872"
     CDS             complement(10847..10966)
                     /locus_tag="VQ865_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine synthetase"
                     /protein_id="HET3136171.1"
                     /translation="MPDIVFEIEFFHSDSLIFFYTSDDKSNSQKSQEDFSKNK"
BASE COUNT         3512 a         2037 c         2414 g         3044 t
ORIGIN      
        1 tagaggtgta ctattctagt ttcaatatac tatatatctg cagaatactc tttcagtttc
       61 attcagccta gtcttgctta ggaaaaagta aaaagccatc caattatgat ggatagcttc
      121 ttggttctta gatttgttct gcaaaaacct tttcagcaag gttcatagcg tggtctgata
      181 cacgagtgta gtgtgagatg atgtcgataa agttgacccc agcttgtgtt gaacattcgc
      241 ctttgttgag gcgtttgatg tgggtttttc tgagaacacg ttctatctta ttgattgctt
      301 catgacgttc tacaagactg cgtgcttttt caatatcatt gttttccaca ctatccagag
      361 catctttgat aaagtcacta gtttggcggt aaacttcctc taattctttc aaggcggcat
      421 cagaaaattc aacatttttc cgttgaagat agtcagtcag attgagtaga gcctccgtgt
      481 ggtctccaat ccgttccaaa tcacgggagg aatcaaggat attggtaagc acttcacttt
      541 ctttttggct gagagcttcg cttgaaaggg caatgagata acgtgttaat tgctcatcga
      601 tggtgttaat tgcttcttcg gttttatgcc ctttttcagc aactttttca tccaagtcaa
      661 tgatgtactt ataggaaagg tcaaaggctt tagcagcgta gtttcctaag tgcaagagct
      721 ctttcttagc atttcctaga gcgatagatg gggcctgttt gatgaaatgt tcatcaagat
      781 ataagggttc gtatttgaca acctcgtcct ctccaggaat aatcttggtt acaaagtaag
      841 ccagagctcc gataaatgga aattggacaa tggtgttggt aatattaaag gttccgtgag
      901 caaaggcgat ggtcatttcc ggtgctagat ttagcgtagc ttcaaaccaa tgaatcagga
      961 cagtaaaagg aactagaaaa ataacgcaga caactgttcc gataacgttg aaggcaacat
     1021 gagctcctgc tacccgttta gctgcaatat tagcccctaa agaggcaatg atggctgtaa
     1081 tggttgtccc gatattgtca ccaaatagaa ctggcaaagc tccctgtagg tcaattagat
     1141 tgccggcgta gaggttttgt aaaatcccaa tggtagccga agaagcttga attagcaagg
     1201 tcaagccagt accgacaaag acacccaaaa caggattctt acttagctca atcatatagt
     1261 ccttaaagac ctgtaaatcc ttgagtggag ccattgcgcc gctcatgaga ttgagggcaa
     1321 aaaagatacc accgacacca aagaggatgc gtccgatatt attgactgtc cgattttttg
     1381 taaaaaagag acagacggca ccgataaaga gcataggtag ggcatagtta cctaatttaa
     1441 aaccgatgag aaaggatgtg acagttgtcc caatattagc acccatgaca atcccgatag
     1501 cctgacgtaa ggttaagaga ccggcactga ccaggccgac tgtaataact gttacaccag
     1561 aactagactg aattagagca gtcatcccaa taccaaccag aactccaaag aaaggattac
     1621 tagtatattt gtcaatgtaa aaacgaaggc gatctccagc agcttgttgc aaaccgtctc
     1681 ccatggtctt gatactatat aagaatagcc ccagaccacc taaaaagtga aataaaattt
     1741 cctgccaatt aatggacatt tctttttcct ccgaaaaata atcgcggaat atctcctatt
     1801 ttattttaaa ggataaaagt aaatctaaca agtgttaatg tcaagtttgt aaaagaaaat
     1861 tataattgat aagtgtatta tttttaagag tttttaacct tattttagat ttgtgaaaac
     1921 agctattgtt ttttgtctaa aaatgtttta ggataaaaat gtgattatca tggttctaga
     1981 gtttgataaa aaactacaga atataaagcg ctttcttgaa aacaacaaaa tcaatctttt
     2041 aggaggagaa aatgaagaat ccattttttg aaagacgttg tcgttacagt attcgtaagt
     2101 tatcagtagg agcctgctcg ctgatgattg gtgctgtttt atttgttggt ccagccttgg
     2161 ctgaagaaac tgcagttcct gaaaatagcg gagctaatac agagcttgtt tcaggagaga
     2221 gtgagcattc gaccaatgaa gctgataagc agaatgaagg ggaacatact agagaaaaca
     2281 agctagaaaa ggcagaagga gtagcgacag catctgaaac tgcagaagca gctagcgcag
     2341 ctaaaccaga ggaaaaagca ggtgaggtgg ttgcagaaac accatctgca gaagcaaaac
     2401 ctaagtctga caaggaaaca gaagcaaagc ccgaagcaac taaccaaggg gatgagtcta
     2461 aaccagcagc agaagctaat aagactgaaa aagaagtcca gccagatgtc cctaaaaata
     2521 cagaaaaaac attaaaacca aaggaaatca aatttaattc ttgggaagaa ttgttaaaat
     2581 gggaaccagg tgctcgtgaa gatgatgcta ttaaccgcgg atctgttgtc ctcgcttcac
     2641 gtcggacagg tcatttagtc aatgaaaaag ctagcaagga agcaaaagtt caagccttat
     2701 caaacaccaa ttctaaagca aaagaccatg cttctgttgg tggagaagag ttcaaggcct
     2761 atgcttttga ctattggcaa tatctagatt caatggtctt ctgggaaggt ctcgtaccaa
     2821 ctcctgacgt tattgatgca ggtcaccgta acggggttcc tgtatacggt acactcttct
     2881 tcaactggtc taatagtatt gcagatcaag aaagatttgc tgaagctttg aagcaagacg
     2941 cagatggtag cttcccaatt gcccgtaaat tggtagacat ggccaagtat tatggctatg
     3001 atggctattt catcaaccaa gaaacaactg gagatttggt taaacctctt ggagaaaaga
     3061 tgcgccagtt tatgctctat agcaaggaat atgctgctaa ggtaaaccat ccaatcaagt
     3121 attcttggta tgatgccatg acctataact atggacgtta ccatcaagat ggtttgggag
     3181 aatacaacta ccaattcatg caaccagaag gagataaggt tccggcagat aacttctttg
     3241 ctaactttaa ctgggataag gctaaaaatg attacactat tgcaactgcc aactggattg
     3301 gtcgtaatcc ttatgatgta tttgcaggtt tggaattgca acagggtggt tcctacaaga
     3361 caaaggttaa gtggaatgac attttagacg aaaatgggaa attgcgcctt tctcttggtt
     3421 tatttgcccc agataccatt acaagtttag gaaaaactgg tgaagattat cataaaaatg
     3481 aagatatctt ctttacaggt tatcaaggag accccactgg ccaaaaacca ggtgacaaag
     3541 attggtatgg tattgctaac ctagttgcgg accgtacgcc agcggtaggt aatactttta
     3601 ctacttcttt taatacaggt catggtaaaa aatggttcgt agatggtaag gtttctaagg
     3661 attctgagtg gaattatcgt tcagtatcag gtgttcttcc aacatggcgc tggtggcaga
     3721 cttcaacagg ggaaaaactt cgtgcagaat atgattttac agatgcctat aatggcggaa
     3781 attcccttaa attctctggt gatgtagccg gtaagacaga tcaggatgtg agactttatt
     3841 ctactaagtt agaagtaact gagaagacca aacttcgtgt tgcccacaag ggaggaaaag
     3901 gttctaaagt ttatatggca ttctctacaa ctccagacta caaattcgat gatgcagatg
     3961 catggaaaga gctaaccctt tctgacaact ggacaaatga agaatttgat ctcagctcac
     4021 tagcaggtaa aaccatctat gcagtcaaac tattttttga gcatgaaggt gctgtaaaag
     4081 attatcagtt caacctcgga caattaacta tctcggacaa tcaccaagag ccacaatcgc
     4141 cgacaagctt ttctgtagtg aaacaatctc ttaaaaatgc ccaagaagcg gaagcagttg
     4201 tgcaatttaa aggcaacaag gatgcagatt tctatgaagt ttatgaaaaa gatggagaca
     4261 gctggaaatt actaactggc tcatcttcta caactattta tctaccaaaa gttagccgct
     4321 cagcaagtgc tcagggtaca actcaagaac tgaaggttgt agcagtcggt aaaaatggag
     4381 ttcgttcaga agctgcaacc acaacctttg attggggtat gactgtaaaa gataccagcc
     4441 taccaaaacc actagctgaa aatatcgttc caggtgcaac agttattgat agtactttcc
     4501 ctaagactga aggtggagaa ggtattgaag gtatgttgaa cggtaccatt actagcttgt
     4561 cagataaatg gtcttcagct cagttgagtg gtagtgtgga tattcgtttg accaagccac
     4621 gtaccgttgt tagatgggtc atggatcatg caggggctgg tggtgagtct gttaacgatg
     4681 gcttgatgaa caccaaagac tttgaccttt attataaaga tgcagatggt gagtggaagc
     4741 tagctaagga agtccgtggc aacaaagcac acgtgacaga tatcactctt gataaaccaa
     4801 tcactgctca agactggcgc ttgaatgttg tcacttctga caatggaact ccatggaagg
     4861 ctattcgtat ctataactgg aaaatgtatg aaaagcttga tactgagagt gtcaatattc
     4921 cgatggccaa ggctgcagcc cgttctctag gcaataacaa ggtacaagtt ggctttgcag
     4981 atgtacaggc tggagcaact attaccgttt atgataatcc aaattctcaa actccgctcg
     5041 caaccttgaa gagcgaagtt ggaggagacc tagcaagtgc accattggat ttgacaaatc
     5101 aatctggtct tctttattat cgtacccagt tgccaggcaa ggaaattagt aatgtcctag
     5161 cagtttccgt tccaaaagat gacagaagaa tcaagtcagt cagcctagaa acaggaccta
     5221 agaaaacaag ctacgccgaa ggggaggatt tggaccttag aggtggtgtt cttcgagttc
     5281 agtatgaagg aggaactgag gacgaactca ttcgcctaac tcacgcaggt gtatcagtat
     5341 caggttttga tacgcatcat aagggagaac agaatcttac tctccaatat ttgggacaac
     5401 cagtaaatgc taatttgtca gtgactgtca ctggccaaga cgaagcaagt ccgaaaacta
     5461 ttttgggaat tgaagtaagt cagaaaccga aaaaagatta cctagttggt gatagcttag
     5521 acttgtctga aggacgcttt gcagtggctt atagcaatga caccatggaa gaacattcct
     5581 ttactgatga gggagttgaa atttctggtt acgatgctca aaagactggt cgtcaaacct
     5641 tgacgcttcg ttaccaaggt catgaagtca actttgatgt tttggtatct ccaaaagcag
     5701 cattgaacga tgagtacctc aaacaaaaat tagcagaagt tgaagctgct aagaacaagg
     5761 tggtctataa ctttgcttca ccagaagtaa aagaagcttt cttgaaagca attgaagcgg
     5821 ccgaacaagt gttgaaagac catgaaatta gcacccaaga tcaagtcaat gaccgactta
     5881 ataaattgac agaagctcat aaagctctga atggtcaaga gaaatttaag gaagaaaaga
     5941 cagagcttga tcgtttaaca ggtgaggttc aagaactctt ggatgccaaa ccaaaccatc
     6001 cttcaggttc tgccctagct ccgcttcttg agaaaaacaa ggtcttggtt gaaaaagtag
     6061 atttgagtcc agaagagctt gcaacagcga aacagagtct aaaagatctg gttgctttat
     6121 tgaaagaaga caagccagca gtcttttctg atagtaaaac aggtgttgaa gtacacttct
     6181 caaataaaga gaagactgtc atcaagggtt tgaaagtaga gcgtgttcaa gcaagtgctg
     6241 aagagaagaa atactttgct ggagaagatg ctcatgtctt tgaaatagaa ggtttggatg
     6301 aaaaaggtca agatgttgat ctctcttacg cttctattgt gaaaatccca attgaaaaag
     6361 ataagaaagt taagaaagta tttttcttac ctgaaggcaa agaggcagta gaattggctt
     6421 ttgaacaaac ggatagtcat gttatcttta cagcaccaca ctttactcat tatgcctttg
     6481 tttatgaatc tgctgaaaaa ccacaacctg ctaaaccagc accacaaaac aaagtccttc
     6541 caaaacctac ttatcaaccg gcttctgatc aacaaaaggc tcctaaattg gaagttcaag
     6601 aggaaaaggt tgcctttcat cgtcaagagc atgaaaatgc tgagatgcta gttggggaac
     6661 aacgagtcat catacaggga cgagatggac tgttaagaca tgtctttgaa gttgatgaaa
     6721 acggtcagcg tcgtcttcgt tcaacagaag tcatccaaga agcgattcca gaaattgttg
     6781 aaattggaac aaaagtaaaa acagtaccag cagtagtagc tacacaggaa aaaccagctc
     6841 aaaatacagc agttaaatca gaagaagcaa gcaaacaatt gccaaataca ggaacagctg
     6901 atgctaatga agccctaata gcaggcttag ccagccttgg tcttgctagt ttagccttga
     6961 ccttgagacg gaaaagagaa gataaagatt aaatatcgaa aaatcttgtg aaatctttcc
     7021 ttatatttcc aaagtgtgat ataatagttt cgaataaaat aaataaagga gtttttgtaa
     7081 catggcaaaa cttactgtta aagacgttga cttgaaaggt aaaaaagtcc tcgttcgtgt
     7141 tgacttcaac gtaccattga aagatggcgt aatcactaac gataaccgta tcacagcagc
     7201 tcttccaact attaagtaca tcatcgaaca aggtggacgt gcaattcttt tctctcacct
     7261 tggacgtgtg aaagaagaag ctgataaagc tggtaaatca cttgctcctg tagcagctga
     7321 cttggcagca aaacttggtc aagatgttgt tttcccaggt gtcactcgtg gtgctgaatt
     7381 ggaagcggca atcaacgctc ttgaagatgg acaagttctc ttggttgaaa acactcgtta
     7441 cgaagatgtt gacggcaaga aagaatctaa aaacgatcct gaacttggta aatactgggc
     7501 atcacttgga gatggtatct tcgtaaacga tgcattcggt acagctcacc gtgcacacgc
     7561 atctaacgtt ggtatctcag caaacgttga aaaagcagtt gctggtttcc ttcttgaaaa
     7621 cgaaattgcc tacatccaag aagcagttga aactccagaa cgtccattcg tggctatcct
     7681 tggtggttca aaagtttcag acaagatcgg tgttatcgaa aacttgcttg aaaaagctga
     7741 taaagtcctt atcggtggtg ggatgactta cacattctac aaagcacaag gtatcgaaat
     7801 cggtaactca cttgtagaag aagacaaatt ggatgttgcg aaagctcttc ttgaaaaagc
     7861 aaatggtaaa ttgatcttgc cagttgactc aaaagaagct aacgcatttg ctggttacac
     7921 tgaagtgcgt gacactgaag gtgaagcagt ttctgaaggc ttccttggtc ttgacatcgg
     7981 tccaaaatct atcgccaaat ttgacgaagc tttgactggt gccaaaacag ttgtatggaa
     8041 cggacctatg ggtgtatttg aaaacccaga tttccaagct ggtacaatcg gtgtgatgga
     8101 cgctatcgtg aaacaaccag gagttaaatc aatcatcggt ggtggtgact cagctgccgc
     8161 agcgattaac cttggccgtg cagacaagtt ctcatggatt agtacgggtg gtggagcatc
     8221 aatggaactt cttgaaggta aggttcttcc aggacttgca gccttgacag aaaaataaga
     8281 ttttataaat aaatcaaaga agagagggat gaaagttcct cttttctttt gcttaaaata
     8341 aaaacgcttc ctctcaacta ttactcataa aaatcaccga tttatgataa aatggaaata
     8401 gaaagttgag attatgagtt attttaaaaa atataaattc gataaatccc agttcaaact
     8461 tggtatgcga acctttaaaa caggtattgc tgtttttcta gttctcttga tttttggctt
     8521 ttttggctgg aaaggtcttc aaattggtgc tttgacagcc gtttttagcc tgagggagag
     8581 ttttgatgag agtgttcatt ttgggacttc gcgtattcta ggaaatagta tcggtggact
     8641 ctatgccttg gtcttcttct tattaaatac ctttttccat gaagcctttt gggtgacctt
     8701 ggtagttgtt ccaatctgca ccatgttaac cattatgaca aatgtagcca tgaataacaa
     8761 agcaggggtt attggtggtg tagcagctat gttaatcatt accctatcaa ttccaagtgg
     8821 tgagacaatt tcgtacgtgt ttgtgcgtgt atcagaaacg tttatgggag tttttgtcgc
     8881 aattatcgta aattacgata ttgatcgtat tcgtctcttt ttagagaaaa aagaaaaata
     8941 atgttacatt ttataacatt atcaattgac gtttgtcttt ttttagacta taatagacag
     9001 aaagaaggaa attgtaaatg aaggaaaaag aatttcgccg aaatatggct gtttttccta
     9061 tcggcagtgt tatgaagttg accgatctat cggcgcgtca gattcgttat tatgaagatc
     9121 aagagttgat caagcccgat cgaaacgaag gaaatcgtcg catgtattcc ttgaatgaca
     9181 tggatcgtct gcttgaaatc aaagattata tctctgaagg ttataatatc gctgccatta
     9241 agaaaaaata tgctgaacgt gaagcgaaat ccaagaaagc ggttagtcag actgaagtac
     9301 gtcgtgcact tcacaatgaa ctcctccaac aggggcgttt tgcttcagta cagtcacctt
     9361 ttggtcgcgg ttaggcaacc gcaagtagtc atagattaag gagaaaactt atgccaatca
     9421 cagctgcaga tattcgtcgt gaagtcaagg aaaaaaatgt tacctttatt cgtcttatgt
     9481 tctcagatat tttgggaacc atgaaaaacg tcgaaattcc tgctacagat gaacagttag
     9541 ataaggtctt gtcgaacaag gttatgtttg atggatcttc tattgaaggt tttgtacgta
     9601 tcaatgagtc ggatatgtac ttgtacccgg acttggatac atggacagtc ttcccttggg
     9661 gagatgaaaa tggaagtgtt gcaggtctga tctgtgatgt ctatacaaca gaaggtgaac
     9721 catttgcggg tgaccctcgt ggtaatttga aacgagctct tcgtcacatg gaagaagttg
     9781 gattcaaatc cttcaacctt ggtccagagc cagaattctt cctatttaag ttggatgaaa
     9841 atggggaccc aacacttgaa gtgaatgaca agggtggcta ctttgatttg gcacctactg
     9901 accttgcgga caacacacgt cgtgagattg tgaatgtctt gaccaaaatg ggatttgaag
     9961 tagaagcgag tcaccacgag gttgcggttg gacagcatga gattgacttt aagtacgatg
    10021 aagttctccg tgcttgtgat aagattcaaa tctttaaact tgttgttaaa accattgctc
    10081 gcaaacacgg actttacgca acatttatgg cgaagccaaa atttggtatt gctggctcag
    10141 gtatgcactg taatatgtcc ttgtttgatg cagaaggaaa taacgccttc tttgatccaa
    10201 atgatccaaa aggaatgcag ttgtcagaaa cagcttacca tttcctaggc ggtttgatca
    10261 agcatgctta caactatact gccatcatga acccaacagt taactcatac aaacgtttgg
    10321 ttccaggtta tgaagcgcct gtttacattg cttgggctgg tcgtaaccgt tcgccacttg
    10381 tgcgcgtacc tgcttcacgt ggtatgggaa ctcgtcttga gttgcgttca gtggatccaa
    10441 tggcgaaccc ttacattgct atggctgttc ttttggaagt tggtttgtat ggtattgaaa
    10501 ataaaatcga agcaccagct cctatcgaag aaaatatcta catcatgaca gcagaagagc
    10561 gcaaggaagc tggtattaca gaccttccat caactcttca taatgctttg aaagctttga
    10621 cagaagatga agtggttaaa gctgctctcg gagatcacat ctacactagc ttccttgaag
    10681 ccaaacgaat cgaatgggca agttatgcaa ccttcgtttc acaatgggaa attgataatt
    10741 atttagacct ttactaatat agaagaaaga ttgcctgtgg gtaaacagtc acacagcagt
    10801 ctaagccatc aaatacctat aacccttaaa atagcgattt cggtcgctat ttatttttcg
    10861 aaaaatcctc ttgactcttt tgcgaattag atttatcatc agacgtgtag aagaaaatca
    10921 aggagtcact atggaaaaat tcaatttcaa aaacaatatc gggcaagaaa acaagttact
    10981 tcaaatcgaa atctacaagt ttactaa
//
LOCUS       DAVBOG010000062        10754 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.062, whole genome shotgun sequence.
ACCESSION   DAVBOG010000062 DAVBOG010000000
VERSION     DAVBOG010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10754)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10754)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10754
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.062"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(117..1541)
                     /locus_tag="VQ865_001873"
     CDS             complement(117..1541)
                     /locus_tag="VQ865_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent glyceraldehyde-3-phosphate
                     dehydrogenase"
                     /protein_id="HET3136172.1"
                     /translation="MTRYQNLVNGKWKSSEQEITIYSPINQEELGTVPAMTQTEADEA
                     MQAARAALPAWRALSAIERAAYLHKTAAILERDKEEIGTILAKEVAKGIKAAIGEVVR
                     TADLIRYAAEEGLRITGQAMEGGGFEAASKNKLAVVRREPVGIVLAIAPFNYPVNLSA
                     SKIAPALIAGNVVMFKPPTQGSISGLLLAKAFEEAGIPAGVFNTITGRGSEIGDYIIE
                     HKEVNFINFTGSTPIGERIGRLAGMRPIMLELGGKDAALVLEDADLEHAAKQIVAGAF
                     SYSGQRCTAIKRVIVLESVADKLATLLQEEVSKLTVGDPFDNADITPVIDNASADFIW
                     GLIEDAQEKEAQALTPIKREGNLLWPVLFDQVTKDMKVAWEEPFGPVLPIIRVASVEE
                     AIAFANESEFGLQSSVFTNDFKKAFEIAEKLEVGTVHINNKTQRGPDNFPFLGVKGSG
                     AGVQGIKYSIEAMTNVKSIVFDVK"
     gene            complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ865_001874"
     CDS             complement(2085..4364)
                     /gene="pulA"
                     /locus_tag="VQ865_001874"
                     /EC_number="3.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000283081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pullulanase"
                     /protein_id="HET3136173.1"
                     /translation="MYNYPMRIHYHRKNGEYDTCSFVKSQDQRIDLLTYKEDYFGALF
                     SFEHPSSHVIESLNFVVHTGQTSKEYSIRFNHYPLLTEVWILEGDDRIYYSENPAIAS
                     PFYKNQNPFAFDKAINSASFDHHWGYQGELGCRVEDNQAHFSLWSPTATEVQVVVYES
                     AANDAPVWKTFEMKRGNSYSYNHKDNTIGVWSLDVEEDLVGKAYQYQVQFPHHQTLTR
                     DPYTIATSPDGKRSAILSHVEKQVENFEVKHGSEATWRLENPCKAVICEMHIRDLTKS
                     PTSGVDEHLRGTFLGAAQAGTVNQYGQSTAFDYIKKLGYNYVQLQPIADRHKEYDEDG
                     NVTYNWGYDPQNYNAPETSFSTNPDDPAQVIRDLKVMVQAYHDAGIGVIMDVVYNHTF
                     SVVDAPFQTTVPDYYYRMNPDGTFQNGTGVGNETASEHEMFRKYMIDSLLYWVQEYNI
                     DGFRFDLMGIHDVKTMQMIRQSLDEIDSNIILYGEGWDMGTGLAPYDKAKKDNAYQMP
                     NIGFFNDNQRDAVKGGEVYGAIKSGFVSGAATEPILAKAILGSRELGSYTHPNQVLNY
                     VEAHDNYNLHDLLATLHPDQSSEQIMRKVETATAMNLLMQGMAFMEIGQEFGRTKLVA
                     TGENGELTHDDRERAMNSYNAPDSVNQVNWNLINERQDSIEFIRQVIRLKTKTGAFSY
                     SSYDEIYHHVFVHSAIEHSGCLIYEVHGKEHLLVVVNAKSEPYQFENAGNLAMLVTNS
                     RSKEDNVLNDISLAVLSVL"
     gene            complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ865_001875"
     CDS             complement(4476..6434)
                     /gene="ligA"
                     /locus_tag="VQ865_001875"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001042597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HET3136174.1"
                     /translation="MNKRMNELVALLNRYATEYYTSDNPSVSDSEYDRLYRELVELET
                     AYPEQVLADSPTHRVGGKVLDGFEKYSHQYPLYSLQDAFSREELDAFDARVRKEVAHP
                     TYICELKIDGLSISLTYEKGILVAGVTRGDGSIGENITENLKRVKDIPLTLPEELDIT
                     VRGECYMPRASFDQVNQARQENGEPEFANPRNAAAGTLRQLDTAVVAKRNLATFLYQE
                     ASPSTRDSQEKGLKYLEQLGFVVNPKRILAENIDEIWNFIQEVGQERENLPYDIDGVV
                     IKVNDLASQEELGFTVKAPKWAVAYKFPAEEKEAQLLSVDWTVGRTGVVTPTANLTPV
                     QLAGTTVSRATLHNVDYIAEKDIRKDDTVIVYKAGDIIPAVLRVVESKRVSEEKLDIP
                     TNCPSCNSDLLHFEDEVALRCINPRCPAQIMEGLIHFASRDAMNITGLGPSIVEKLFA
                     ANLVKDVADIYRLQEEDFLLLEGVKEKSAAKLYQAIQASKENSAEKLLFGLGIRHVGS
                     KASQLLLQYFHSIENLYQADSEEVASIESLGGVIAKSLQTYFATEGSEILLRELKETG
                     VNLDYKGQTVVADAALSGLTVVLTGKLERLKRSEAKSKLESLGAKVTGSVSKKTDLVV
                     VGADAGSKLQKAQELGIQVRDEAWLESL"
     gene            complement(6527..7705)
                     /locus_tag="VQ865_001876"
     CDS             complement(6527..7705)
                     /locus_tag="VQ865_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001083019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3136175.1"
                     /translation="MNRYAVQLISRGAINKMGNMLYDYGNSVWLASMGTIGQTVLGMY
                     QISELVTSILVNPFGGVISDRFSRRKILMTADLVCGILCLAISFIRNDSWMIGALIVA
                     NIVQTIAFAFSRTANKAIITEVVEKDEIVIYNSRLELVLQVVGVSSPVLSFLVLQFAS
                     LHMTLLLDSLTFFIAFVLVAFLPKEEAKVQEKKAFTGRDIFVDIKDGLHYIWHQQEIF
                     FLLLVASSVNFFFAAFEFLLPFSNQLYGSEGAYASILTMGAIGSIIGALLASKIKANI
                     YNLLILLALTGVGVFMMGLPLPTFLSFSGNLVCELFMTIFNIHFFTQVQTKVESEFLG
                     RVLSTIFTLAILFMPIAKGFMTVLPSVHLSSFLIIGSGVIILSCISFIYVRTHFEKLI
                     "
     gene            complement(7785..8648)
                     /locus_tag="VQ865_001877"
     CDS             complement(7785..8648)
                     /locus_tag="VQ865_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE/MutR family transcriptional regulator"
                     /protein_id="HET3136176.1"
                     /translation="MEHLGKVFREFRTSGNYSLKEAAGESCSTSQLSRFELGESDLAV
                     SRFFEILDNIHVTIENFMDKARNFHNHEHVSMMAQIIPLYYSNDIAGFQKLQREQLEK
                     SKSSTTPLYFELNWILLQGLICQRDASYDMKQDDLDKVADYLFKTEEWTMYELILFGN
                     LYSFYDVDYVTRIGREVMEREEFYQEISRHKRLVLILALNCYQHCLEHSSFYNANYFE
                     AYTEKIIDKGIKLYERNVFHYLKGLALYQKGQCKEGCKQMQEAMHIFDVLGLPEQVAY
                     YQEHYEKFVKS"
     gene            complement(8651..10552)
                     /locus_tag="VQ865_001878"
     CDS             complement(8651..10552)
                     /locus_tag="VQ865_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000584877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HET3136177.1"
                     /translation="MIILQANKIERSFAGEVLFDNINLQVDERDRIALVGKNGAGKST
                     LLKILVGEEEPTSGEINKKKDISLSYLAQDSRFESENTIYDEMLHVFNNLRRTERQLR
                     QMELEMGEKSGEDLDKLMSDYDRLSENFRQAGGFTYEADIRTILNGFKFDESMWQMKI
                     AELSGGQNTRLALAKMLLEKPNLLVLDEPTNHLDIETIAWLENYLVNYSGALIIVSHD
                     RYFLDKVATITLDLTKHSLDRYVGNYSRFVELKEQKLVTEAKNYEKQQKEIAALEDFV
                     NRNLVRASTTKRAQSRRKQLEKMERLDKPEAGKKAANMTFQSEQTSGNVVLTVENTAI
                     GYDGEVLSQPINLDLRKMNAVAIVGPNGIGKSTFIKSIVDQIPFIKGEKRFGANVEVG
                     YYDQTQSKLTPSNTVLDELWNDFKLTPEVEIRNRLGAFLFSGDDVKKSVGMLSGGEKA
                     RLLLAKLSMENNNFLILDEPTNHLDIDSKEVLENALIDFDGTLLFVSHDRYFINRVAT
                     HVLELSENGSTLYLGDYDYYVEKKVTAEMSQTEEASTSNQAKEASPVNDYQAQKESQK
                     EVRKLMRQIESLEAEIEELESQSQAISEQMLETNDADKLMELQAELDKISHRQEEAML
                     EWEELSEQV"
BASE COUNT         3220 a         2371 c         1916 g         3247 t
ORIGIN      
        1 tgtactattc tagtttcaat atactataat accaaaaagt tcgtattttt tctataatta
       61 ttattatttt atagcaaaaa aataaaacca ggaaaacaat ttcctgattt tacacgttat
      121 ttcacatcaa aaacaatgga tttgacattt gtcatcgctt caatgctata tttaatccct
      181 tgcactccag ctccagaacc tttgacacca aggaacggga aattatctgg accacgctgg
      241 gttttattat taatgtggac tgtacctact tcaagttttt cagcaatttc aaaggctttt
      301 ttgaaatcat ttgtaaagac tgatgattga aggccgaatt cagattcgtt ggcaaaggca
      361 atagcttcct ctacactagc cacacgaatg attggtaaaa caggaccaaa tggctcttcc
      421 catgccactt tcatatcttt tgtaacttgg tcaaaaagca ctggccagag gagattgccc
      481 tcacgtttga ttggtgtaag agcctgagcc tctttttctt gtgcatcctc aatcaagccc
      541 caaatgaagt cggctgaagc attgtcaata acaggtgtaa tatcagcatt gtcaaatgga
      601 tcaccaactg ttaatttaga aacttcttcc tgaagcaaag tagctaattt atctgctaca
      661 ctttcgagaa caatgacacg tttaatggcc gtgcaacgtt gtcctgagta gctaaaggct
      721 cccgcaacaa tttgcttggc agcatgttcc aaatctgcat cttctagtac aagagctgca
      781 tctttcccac caagttccaa catgatagga cgcataccag ctaaacgacc aatacgttct
      841 ccaataggag ttgaacctgt aaagttgatg aagttgactt ctttgtgctc aatgatataa
      901 tccccaattt ctgaaccacg acctgtaatg gtgttgaaaa cacctgccgg aatccctgct
      961 tcttcaaatg ctttagccaa caagagtcca gaaatggaac cttgtgttgg tggcttaaac
     1021 atgaccacat tccctgcaat caaggcaggt gcaattttag aagcagataa attaactgga
     1081 taattaaagg gagcaatcgc tagcacgata ccaactggtt cacgacggac aacagccagt
     1141 ttgtttttac ttgctgcctc aaaaccacca ccttccattg cttgtccagt gatacggaga
     1201 ccttcctcag cagcataacg aatcaagtct gctgtacgca ctacttctcc aattgctgct
     1261 ttaatccctt ttgctacttc tttggcaagg atagtaccaa tttcttcctt atcgcgttct
     1321 aaaatagctg ctgttttatg caaataagcc gcacgttcaa ttgctgataa agctcgccat
     1381 gctggcaggg ctgcacgcgc agcttgcata gcctcatcag cttcagtctg agtcatggct
     1441 ggaactgtac ccaattcttc ttgattgatt ggtgaataaa tcgtaatttc ttgttcagat
     1501 gatttccatt ttccatttac taaattctga tatcttgtca aattcttgtc ctcctgaaaa
     1561 tgattaagat atattttacc aaattttcag aaaaccacaa ccctttttgc gaaatttttg
     1621 agattatttt cacaagcttg atttttcaaa gtatactcaa taaaaataaa aaaatccact
     1681 acgtcaaggc gaggctaatg tggtttgaag aaattttcga agagcgtgaa tgagtatcat
     1741 ctatagtaaa ataaaaaaac tgaacaattt ggtttgggac agtcaaacca atttctcaca
     1801 atgttttaga aacacgggtg tgctattcca atttcaggct actataactg tcatagattg
     1861 ctgaaacaaa gtctaggtaa aagtcttcat aataaaaaga cctcctatca aatgttcaaa
     1921 aactttgata ggaggtcttg tttcgtgaaa atatttatca aattttctat acaagtgagc
     1981 tgttagccag gttctttcta ttctttcaat ttcaatgaat ggatttttta ccaatactca
     2041 taactgggaa tttttctgtg taaaaatagc gagatagatg gtatttataa aacactcaag
     2101 acagctagac taatatcatt taaaacatta tcttcttttg agcgactgtt ggttaccaac
     2161 atagctaaat ttcctgcatt ttcaaattga tagggttctg atttagcatt cacaaccacc
     2221 aagaggtgtt ctttgccgtg aacttcatag ataaggcagc cgctatgttc aatcgccgaa
     2281 tgcacaaaga catgatggta aatttcatca tagctagagt aagaaaaggc accagttttt
     2341 gtcttcaatc ggatgacttg acggataaac tcaatactgt cttgacgctc attaatcaag
     2401 ttccagttca cttggttcac actgtcagga gcattatagc tattcatcgc acgctctcta
     2461 tcatcatggg tcaactcacc attttcacca gtcgcaacca gtttggtacg accaaattct
     2521 tgaccgattt ccataaaggc catcccctgc atgagcagat tcatggctgt ggcagtttcg
     2581 accttgcgca tgatttgctc tgaactttgg tctggatgaa gggttgccaa taaatcgtga
     2641 agattgtaat tgtcatgggc ttctacatag ttaagcacct gatttggatg tgtatagctt
     2701 cctaattcac gacttcctag gattgcttta gctagaattg gctctgtcgc agcaccactg
     2761 acaaaacctg acttgatagc accataaact tctccccctt tgacagcatc gcgctgattg
     2821 tcattaaaga aaccaatatt tggcatctgg taggcattgt ccttcttggc cttatcataa
     2881 ggggcaagac ctgttcccat atcccatcct tctccataga ggataatgtt ggagtcgatt
     2941 tcatccaagc tttgacgaat catctgcatg gtcttgacat catgaatccc catcaagtca
     3001 aaacggaagc cgtcaatatt atattcctgc acccagtata gaagagaatc aatcatatac
     3061 ttgcgaaaca tttcgtgttc actggctgtt tcatttccaa cacccgttcc attctggaag
     3121 gtaccatctg gattcatacg ataatagtaa tcagggactg ttgtttggaa tggtgcatca
     3181 acaactgaga aggtatggtt atagactaca tccataatga ctccaatacc cgcatcgtga
     3241 taagcttgaa ccatcacctt caaatcacga atgacctgag ctggatcatc tggattagtt
     3301 gaaaaactag tttctggcgc gttatagttt tgtggatcat aaccccagtt gtaggttaca
     3361 tttccatcct catcgtattc tttatgacgg tctgcaattg gttgcaattg aacataattg
     3421 tagcccagct tcttgatgta atcaaaagca gttgactggc cgtattggtt aactgttcca
     3481 gcctgagcag cacccaagaa agttcctcga agatgttcat ctacacccga tgtaggtgat
     3541 ttagtcaaat cacgaatgtg catttcacag ataactgcct tacatggatt ttccaagcgc
     3601 caagtagcct ccgaaccgtg cttaacctcg aagttttcaa cttgcttttc tacatggctc
     3661 agaatagctg aacgtttgcc atcagggctg gtcgcgattg tataaggatc acgtgtcagt
     3721 gtttggtgat gagggaattg gacttgatac tgataagcct tacctaccaa atcttcctca
     3781 acatccaaac tccagacacc gattgtattg tccttatgat tataagagta gctattgcct
     3841 cttttcatct caaaagtctt ccaaacgggt gcatcattag cagctgattc ataaacgaca
     3901 acttgcactt ctgtcgctgt aggtgaccag agggaaaaat gagcctgatt gtcctctaca
     3961 cggcaaccca attctccttg gtaaccccaa tgatggtcaa aactagcact gttaatggcc
     4021 ttatcaaagg caaaaggatt ttgattttta tagaaaggac tggcaatagc aggattttca
     4081 gagtaataaa tcctatcatc gccttccaaa atccagactt ctgttaatag gggatagtga
     4141 ttaaaacgga tagaatattc tttactagtt tgacctgtat gaaccacaaa attcaagctt
     4201 tctataacat gtgaacttgg gtgttcaaag ctaaataaag ctccaaaata atcttctttg
     4261 taggttagca aatcaattcg ttgatcctga ctttttacaa aggagcaagt gtcatattca
     4321 ccattcttgc gatggtaatg aatgcgcata gggtagttat acatttttta tttttccttt
     4381 ttactttgtt tctatttcac taataaattt ttgtcaatct cgtctcaatt aacagacata
     4441 gtcatattct ctaaactctg tttttaaacg atccattaca aactttctag ccatgcctca
     4501 tctctgacct ggataccaag ttcttgtgct ttttgcagtt tacttccagc gtctgcacct
     4561 accacgacga ggtcggtctt tttagaaaca ctacctgtca ctttggcacc cagactttcg
     4621 agtttacttt tagcttctga gcgcttgagt cgttccaatt ttcctgtcaa taccacggtc
     4681 aaacctgaca aggccgcatc cgctactacc gtctgtcctt tatagtccag attgacccca
     4741 gtttctttca attctctgag cagaatttca gagccttctg tcgcaaaata agtctgaaga
     4801 cttttggcaa tcacgccacc tagactttca atactagcca cttcctctga atctgcctga
     4861 tacagatttt caattgaatg gaaatattga agtaaaagct gactagcctt gcttccgaca
     4921 tgacgaattc ccaaaccaaa taagagcttc tcggcagaat tttcctttga tgcttggata
     4981 gcctgataca gtttagcagc ggacttttcc ttaaccccct ctaaaaggag gaaatcctct
     5041 tcttgcaaac gataaatatc cgccacatcc ttgactaaat tagcagcaaa aagcttctca
     5101 acaatagatg gaccaaggcc tgtaatattc atagcatcac gagaagcaaa gtgaatcaag
     5161 ccttccatga tttgagcagg gcaacgcgga ttgatacaac gtagggccac ttcatcttca
     5221 aagtgcaaca agtcagagtt acaacttgga cagtttgtag ggatatctag tttttcttca
     5281 gaaacccgtt tggactctac cacacgtaaa acggcaggga tgatgtcacc agccttatat
     5341 acaatgaccg tatcgtcttt tcggatatct ttttcagcaa tataatctac attgtgcagg
     5401 gtcgcacggc taacagtcgt accggcaagt tgtactggtg ttagattagc agttggagtt
     5461 acaacaccgg tacggccaac tgtccagtca actgataaga gttgagcttc tttttcttca
     5521 gcagggaact tgtaggctac tgcccacttt ggagccttaa cggtaaaacc aagttcttct
     5581 tgacttgcta ggtcgttgac cttgattacc actccatcaa tatcgtaagg tagattttcc
     5641 cgttcctgtc ctacttcttg gataaaattc cagatttcat ctatgttttc agccaagatt
     5701 cgcttaggat tgaccacaaa acctagttgt tctaggtact tcaaaccctt ttcttggcta
     5761 tcacgagttg aaggactggc ttcttgatag agaaacgttg caagattacg ctttgcaact
     5821 actgctgtat ccaactgacg cagagttcct gctgccgcat tacgaggatt agcaaattca
     5881 ggctctccat tttcttggcg cgcttggtta acttggtcaa aggaagcgcg tggcatgtaa
     5941 cattccccac gaactgtgat atctagttct tctggcaaag tcaaagggat gtccttaaca
     6001 cgcttgaggt tttctgtgat attttcacca attgaaccat ctccacgtgt taccccagca
     6061 accaaaatcc ccttttcata agtcagcgag atagataagc catcgatttt cagctcacaa
     6121 atataggtcg gatgagccac ttccttacga acacgcgcat caaaagcatc tagctcctca
     6181 cgtgaaaaag catcctgcaa actataaaga ggatactgat gactgtattt ttcaaaacca
     6241 tctaaaacct tgccaccaac acgatgagtc ggactgtctg ctagcacttg ctctggataa
     6301 gcagtttcta actcgaccaa ctcacggtaa aggcggtcat actcactgtc tgaaaccgag
     6361 ggattatcgc tggtatagta ctcagtcgca tagcgattga gcaaagcgac taactcattc
     6421 attcttttat tcataagacc attttaccat aaaacaagcc ctcctcacaa acgagaaggg
     6481 cggaaaaaac acttagtttg aaattatttt tgaaactcaa gcaaccttat atcaattttt
     6541 caaaatgagt tcgaacataa ataaacgata tacaagacaa gatgataaca ccacttccaa
     6601 ttatcaggaa agaagagaga tgtacacttg gcaagactgt cataaatcct tttgcaatag
     6661 gcataaatag aatagctaag gtaaaaattg tactcagtac tctcccaaga aattcgctct
     6721 caaccttggt ttgtacttga gtaaaaaagt gaatattaaa aatcgtcata aacaattcac
     6781 aaactaaatt tccagaaaag gaaagaaaag ttggaagtgg taatcccatc ataaaaactc
     6841 cgacacctgt caaagccagt aaaatcaaaa gattataaat attagcttta attttactag
     6901 ctagaagagc cccaatgatg gaaccaatag cccccatagt taaaatactt gcataggctc
     6961 cttctgaccc gtaaagctga ttcgaaaagg gaagtagaaa ttcaaaagct gcaaaaaaga
     7021 aattaacgct ggaagctacc agcaaaagga agaaaatttc ttgctgatgc cagatatagt
     7081 gtaacccatc cttgatatct acaaaaatat ctctcccagt aaaagccttt ttctcttgaa
     7141 cttttgcttc ctcttttgga aggaaagcca ctagaacaaa agcaatgaaa aaagtcagcg
     7201 agtctagcag tagcgtcata tggagacttg caaactgtaa aacaaggaag gaaagaacag
     7261 gagagctaac acctacaacc tgcaaaacca gctctaagcg agaattatag atcacaatct
     7321 catctttctc caccacttca gttatgatag ctttattggc tgtgcgagaa aaggcaaaag
     7381 caatagtctg cacaatgtta gcaacaatca aagcgccaat catccagcta tcattcctta
     7441 tgaaagaaat agccagacaa agaatcccac aaacaagatc tgccgtcatt aaaatcttac
     7501 gacgagaaaa acggtctgaa ataactccgc caaagggatt gacgagaata gatgtgacga
     7561 gctcagaaat ctgatacatt cctaaaactg tctgtcctat agtccccata gaagccaacc
     7621 agacactatt tccataatca tagagcatat ttcccatttt attgatagcc ccacggctaa
     7681 tcaactgcac tgcatagcga ttcatattaa agctcctctc aaattttgaa actattgtat
     7741 caaaaccgaa aggagctttt tattttttcc cttatttggg aaaattaact tttgacaaat
     7801 ttttcgtagt gttcctgata ataggctact tgctctggaa gacctaacac atcaaaaata
     7861 tgcatggcct cttgcatctg cttacagcct tctttacact gtcctttttg atataaggcc
     7921 aaacctttta aataatggaa aacattacgc tcataaagct taataccttt gtcaataatc
     7981 ttctctgtat aagcctcaaa atagttggca ttataaaaag aagaatgctc taaacaatgc
     8041 tggtaacaat tgagggccaa aattaacact aatctcttat ggcgactaat ctcttggtaa
     8101 aattcctccc tctccataac ttctctacca atccgagtga catagtctac atcgtagaaa
     8161 ctatagaggt taccgaaaag aatcaactca tacatggtcc attcttctgt tttgaagaga
     8221 taatctgcta ccttatccaa atcatcctgc ttcatatcat aactcgcatc tctttgacaa
     8281 atcagacctt gtagcaaaat ccagttcagc tcaaaataaa ggggagtcgt cgaactctta
     8341 gacttttcaa gttgttctct ttgaagcttt tgaaaacctg caatatcgtt tgaatagtaa
     8401 agtgggataa tctgtgccat catagacaca tgttcatgat tatgaaaatt ccttgcctta
     8461 tccatgaaat tttcgattgt tacatgaatg ttatccaaaa tctcaaagaa acgggagact
     8521 gccaggtcag actccccaag ctcaaagcga gataactgag aggtagagca ggattcgcct
     8581 gctgcttcct ttaaagaata atttccactt gttcgaaatt cacgaaatac ttttccaaga
     8641 tgttccatct ttacacctgc tctgataatt cttcccactc aagcatagct tcttcctgac
     8701 gatggctgat tttgtccagc tcagcctgta attccatgag tttgtcggca tcgtttgttt
     8761 ccaacatttg ttcagaaatg gcttggcttt gactttctag ctcttcaatt tcagcttcta
     8821 gactttcgat ttgtcgcatg agtttgcgaa cttctttttg actttctttc tgggcctgat
     8881 agtcattgac tggacttgct tcctttgctt gattgctagt tgaagcttcc tcagtctgac
     8941 tcatttctgc tgttactttc ttctcaacat agtagtcgta atctccaagg tagagagttg
     9001 aaccattctc agacaattcc aaaacatgag ttgccacacg attgataaag taacgatcat
     9061 gactgacaaa aagcaaggta ccatcaaagt caatcaaggc attttctagc acttccttac
     9121 tatcaatatc caagtggttg gtcggctcat ccagaatcaa aaagttattg ttttccatag
     9181 acaatttggc taaaagcaaa cgagcttttt cgccaccaga tagcatgccg actgattttt
     9241 taacatcatc tcctgagaaa aggaaggctc caagacggtt gcggatttca acttctggtg
     9301 tcagtttgaa atcattccag agttcatcca gcaccgtatt acttggtgtc agcttgcttt
     9361 gggtttggtc atagtaacca acctcaacat tagcgccaaa gcgcttttct cccttgataa
     9421 acggaatttg atccacgatt gatttgataa aggttgattt tccgatacca ttgggaccaa
     9481 cgatagcgac agcattcatc ttacgaagat ctaggttgat aggttgtgac aagacttccc
     9541 cgtcataacc aatagcagta ttttcaacag tcaaaacaac attgcccgac gtttgttcag
     9601 actggaaggt catgttggct gctttcttgc cagcttcagg cttgtccaaa cgctccattt
     9661 tttctagttg tttacggcga gattgagcac gtttagtcgt tgaagcacga actagattgc
     9721 gattgacaaa gtcttccaga gcagcgattt ccttctgttg cttttcatag ttttttgcct
     9781 cagtaactag cttttgctcc ttcaattcga caaaacgaga gtaattcccc acatagcgat
     9841 ccaaggaatg cttggtcaaa tctagcgtaa ttgtcgcaac cttgtccaag aaataacggt
     9901 cgtggctgac gataatgagg gcaccgctat agtttaccaa gtaattctct agccaggcga
     9961 tggtttcaat atccaagtgg ttagttggct cgtccaagac caagagattg ggcttttcaa
    10021 ggagcatttt ggcaagtgcc aaacgagtat tttgaccacc agaaagctca gcaattttca
    10081 tctgccacat agactcgtca aacttgaatc cattcaaaat cgttcgaata tcagcttcat
    10141 aggtaaagcc acctgcttgg cgaaaattct cagataagcg gtcataatct gacatcagtt
    10201 tatccaaatc ctcaccagac ttttcaccca tctccagctc catctgacgc agttgtctct
    10261 ccgtccgacg caaattatta aagacatgaa gcatttcatc gtagatggta ttttcagact
    10321 caaaacggct atcttgggct aggtaagaca gagaaatatc ttttttctta ttgatttctc
    10381 cgctagttgg ctcctcttct ccaactaaaa tcttcaaaag agtagactta cctgcaccat
    10441 ttttcccaac aagggcaatc cgatctcgtt catcaacctg caggttgata ttatcgaaaa
    10501 gaacctctcc tgcaaaagaa cgttcaattt tattagcttg taaaataatc ataagagtag
    10561 tatagcatgt ttccctaagg cattcaagat aatcgtaagt cttttagtac aacttttata
    10621 acataaaata aactaaatta tgtatatttt atattagatt cttcactatc ttgttggatt
    10681 ttctaaccag ctaatcttgt ttcaaatagt tatcgcacaa gcctattatt taattctttt
    10741 cattatttac gtac
//
LOCUS       DAVBOG010000063        10641 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.063, whole genome shotgun sequence.
ACCESSION   DAVBOG010000063 DAVBOG010000000
VERSION     DAVBOG010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10641)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10641)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10641
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.063"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(166..969)
                     /locus_tag="VQ865_001879"
     CDS             complement(166..969)
                     /locus_tag="VQ865_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic/DOC family protein"
                     /protein_id="HET3136178.1"
                     /translation="MQSTYNIDNPNLSYEAKRDLWRIGFGLQKVDNLVPSAYMESLAE
                     KQSRGELTYEQVYEDATAYHHTIDASTEEADLVSLRIVELLSRRGFSFSPATLLAIHK
                     ELFQDIFEPSIPVGQFRQTNITKNEPVLNGESVVYSDYSMIQMTLDYDFNQEKQVAYA
                     TLTQADVVKQIQHFISGIWQIHPFREGNTRTVTVFLIQYLREFGFDIDNIPFQQHSKY
                     FRDALVLDNAKILQRRPEFLTAFFENLLLGGQNDLSSEKMYLDLDLDFS"
     gene            complement(1244..1999)
                     /locus_tag="VQ865_001880"
     CDS             complement(1244..1999)
                     /locus_tag="VQ865_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000033780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3883 domain-containing protein"
                     /protein_id="HET3136179.1"
                     /translation="MSKHPHYELLNLIGYGLAKFAKLFIKEFQYSSKSEFYRYVVSLG
                     IAETTGVVKNRMDLFDPYFDNSRKGWWQKAEVYRFRKDLIDMMFGNEDVHSYVEIVKM
                     LLASEGKQTGITIIEKPIIRTKFKRLQETGMEAENYFILHFDKEEKFQGGQLTDACLY
                     GDGYDFQVDIQEHSYLAEVKGIRKPKGRVRLTAYEFEKAKEFQSDFILSLVTNLDDIP
                     KLVLVDNPLKHFEFKKNIIKNEIIEYRSVEDLY"
     gene            complement(2069..4720)
                     /locus_tag="VQ865_001881"
     CDS             complement(2069..4720)
                     /locus_tag="VQ865_001881"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009732359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HET3136180.1"
                     /translation="MSKELSSKYNPAEVEAGRYQKWLDADVFKPSGDQKAKPYSIVIP
                     PPNVTGKLHLGHAWDTTLQDIIIRQKRMQGFDTLWLPGMDHAGIATQAKVEERLRGEG
                     ISRYDLGRESFLTKVWEWKDEYATTIKEQWGKMGLSVDYSRERFTLDEGLSKAVRKVF
                     VDLYKKGWIYRGEFIINWDPAARTALSDIEVIHKDVEGAFYHMNYMLEDGSRALEVAT
                     TRPETMFGDVAVAVNPEDPRYKDLIGKNVILPIANKLIPIVGDEHADPEFGTGVVKIT
                     PAHDPNDFLVGQRHNLPQVNVMNDDGTMNELAFEFSGMDRFEARKAVVAKLEEIGALV
                     KIEKRVHSVGHSERTGVVVEPRLSTQWFVKMDQLAKNAIANQDTEDKVEFYPPRFNDT
                     FLQWMENVHDWVISRQLWWGHQIPAWYNADGEMYVGEEAPEGDGWTQDEDVLDTWFSS
                     ALWPFSTMGWPEVDSEDFKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGRQPFQNVL
                     IHGLIRDEEGRKMSKSLGNGIDPMDVIDKYGTDSLRWFLSNGSAPGQDVRFSYEKMDA
                     SWNFINKIWNISRYILMNNEGLTLDVAHDNVTKVATGEAGNVTDRWILHNLNETIAKV
                     TENFDKFEFGVAGHILYNFIWEEFANWYVELTKEVLYSDNEDDKVITRSVLLYTLDKI
                     LRLLHPIMPFVTEEIFGQISEGSIVTAAYPTVNLAFEDLAAHTGVESLKDLIRAVRNA
                     RAEVNVAPSKPITILVKTSDSDLEAFFNSNVNYIKRFTNPEHLEIASTIPAPELAMSS
                     VITGAEIYLPLADLLNVEEELARLDKELAKWQKELDMVGKKLSNERFVANAKPEVVQK
                     ERDKQADYQAKYDATVARIDEMKKLVK"
     gene            complement(4713..5291)
                     /locus_tag="VQ865_001882"
     CDS             complement(4713..5291)
                     /locus_tag="VQ865_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000550018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3136181.1"
                     /translation="MHLFIIGAPASGKMTIGQELSRLTDATLFYNHQAIDFALEIYQD
                     YTEEMWEFVRGITFSFLGASARNQRSVILTDVIDFSNQYHLIYLKQIQNLLDDYHQEI
                     LFVELETSLEECIRRNRTENRLKHKPLKRHIEVSEREILETAETLQLNSQYQPNELHH
                     YFKINNTNLSAEEAAKQIQNKINKIEKGHTHV"
     gene            complement(5291..5851)
                     /locus_tag="VQ865_001883"
     CDS             complement(5291..5851)
                     /locus_tag="VQ865_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000124561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136182.1"
                     /translation="MARTELPDKIETERLVLRVRTVADAEDIFDYASLPEVAYPAGFP
                     PVKTLEDEIYYLEHILPERNQKENLPAGYGIVVKGTDKIVGSIYFNHRHEDDVMEIGY
                     TLHSDYWGRGYVPEAARALIDLAFKDLGLHKIELTCFGYNLQSQRVAEKLGFTLEARI
                     RDRKDAQGNCCDDLRYALLKSEWGVI"
     gene            complement(5838..6287)
                     /locus_tag="VQ865_001884"
     CDS             complement(5838..6287)
                     /locus_tag="VQ865_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase"
                     /protein_id="HET3136183.1"
                     /translation="MIGVVARENAAEQIKQYQKFTVNISDETSMLAMEQAGFISHQEK
                     LERLGVHYEISERTQTPILDACPLVLDCRVDRIVEEDGICHIFAKILERLVAPELLDE
                     KGHFKNQLFAPTYFMGDGYQRVYRYLDKRVDMKGSFIKKARKKDGKN"
     gene            complement(6700..7095)
                     /locus_tag="VQ865_001885"
     CDS             complement(6700..7095)
                     /locus_tag="VQ865_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000038635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HET3136184.1"
                     /translation="MSKKLNRKKQLRNGLRRAGAFSSTVTKVVDETKKVVKRAEQTAS
                     AAGKAVSKKVEQAVEATKEQAQKVANSVEDFAANLGGLPLDRAKTFYDEGIKSASHFK
                     NWTEKELLDLKGIGPATIKKLKENGIKFK"
     gene            complement(7191..7445)
                     /locus_tag="VQ865_001886"
     CDS             complement(7191..7445)
                     /locus_tag="VQ865_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000119704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1912 family protein"
                     /protein_id="HET3136185.1"
                     /translation="MSYEQEFMKEFEAWVNTQIMINDMAHKESQKVYEEDQDERAKDA
                     MIRYESRLDAYQFLLGKFENFKVGKGFHDLPEGLFGERNY"
     gene            complement(7455..8789)
                     /locus_tag="VQ865_001887"
     CDS             complement(7455..8789)
                     /locus_tag="VQ865_001887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000752887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF438 domain-containing protein"
                     /protein_id="HET3136186.1"
                     /translation="MADERIHVLRDILLELHNGASPESVQERFDATFAGVSAIEISLM
                     EHELMNSDSGVTFEDVMELCDVHANLFKNAIKGVEVSDTEHPGHPVRVFKEENLALRA
                     ALIRIRRLLDTYESMEDEEMLAEMRKGLVRQMGLVGQFDIHYQRKEELFFPIMERYGH
                     DSPPKVMWGVDDQIRELFQTALTTAKSLPEVSISSVKEAFEAFATEFESMIFKEESIL
                     LMILLESFTQDDWLQIAEESDAYGYAIIRPSEKWVPERQIFIEEKIAEEPVQLDTAEG
                     QVQQVIDTPEGHFTITFTPKEKEAVLDRHSQQAFGNGYLSVEQANLILNHLPMEITFV
                     NKEDIFQYYNDNTPADEMIFKRTPSQVGRNVELCHPPKYLDKVKAIMKGLREGTKDKY
                     EMWFKSESRGKFVHITYAAVHDEDGEFQGVLEYVQDIQPYREIDTDYFRGLE"
     gene            complement(8789..9022)
                     /locus_tag="VQ865_001888"
     CDS             complement(8789..9022)
                     /locus_tag="VQ865_001888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006144975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1858 domain-containing protein"
                     /protein_id="HET3136187.1"
                     /translation="MDNIIDVSIPVAEVVDKHPEVLEILVELGFKPLANPLMRNTVGR
                     KVSLKQGSKLAGTPMDKIVRTLEANGYEVIGLD"
     gene            complement(9335..9475)
                     /locus_tag="VQ865_001889"
     CDS             complement(9335..9475)
                     /locus_tag="VQ865_001889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000668195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136188.1"
                     /translation="MKFFWGLLAIIFIKPIIGIVKFFWMIISFAVQLLFYKILDWFFK
                     LI"
     gene            complement(9472..9654)
                     /locus_tag="VQ865_001890"
     CDS             complement(9472..9654)
                     /locus_tag="VQ865_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001068155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136189.1"
                     /translation="MNPIKAFAKIYGNYFLTVQGVKVMKTIKKDDNAVVGLGKLFIAD
                     KLMDTARWLIKPEDKK"
     gene            complement(9656..10435)
                     /locus_tag="VQ865_001891"
     CDS             complement(9656..10435)
                     /locus_tag="VQ865_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136190.1"
                     /translation="MAEQDLAMQVLQQVVKLPVVKVDRSKFLVDKFSKELGPQDIPTL
                     LEQGPTSLLSQEILDRVANACIRDNVLLASGTSVLAGLPGGLAMAITIPADVAQFYGF
                     SLKLAQELGYIYGYEDLWASRDELSEDAQNTLLLYLGVMLGVNGTAALLRAGGITIAK
                     QVMKTVPNKALTKTLWYPILKKVLRIFGVNLTKGGLAKGMGKFIPILGGIISGGLTFA
                     TMKPMGESLQKELSKLVNYSEVQYQEDVETIRKEAEIIKGE"
BASE COUNT         3109 a         2369 c         1971 g         3192 t
ORIGIN      
        1 aactaaaagg acttagccct gtgcaataca gaactaaatc cttcggataa attaattgtc
       61 taactgtttg gggtcagtac attttaacac ttgatactat gcgttttatt gtgggaatgt
      121 ttacttcatt ttttcctaaa attcaatgtt tactcagtat ttggattatg aaaaatcgag
      181 gtctaaatct agatacattt tttctgaaga caaatcattt tgaccaccga gcaagagatt
      241 ttcaaaaaaa gctgttaaaa actcaggacg tcgctgtaaa atctttgcat tatctaatac
      301 caaggcatca cgaaaatact tggaatgttg ctgaaatggt atattatcaa tatcaaaacc
      361 aaactcacga agatactgaa tcaaaaagac cgttactgtc cgagtgtttc cttcgcgaaa
      421 tggatgaatc tgccagattc ctgaaataaa atgctggatt tgtttaacca catccgcctg
      481 agttagtgtc gcatatgcaa cttgtttttc ctgattaaaa tcataatcta aggtcatttg
      541 aatcatggag taatcagagt acacaacact ttcaccattc aaaacaggtt cattctttgt
      601 gatattggtc tgacgaaatt gccccaccgg aatagagggt tcaaatatat cttgaaacaa
      661 ctccttatga atagcaagta aggtcgcagg actaaagcta aagcctcttc gagacaatag
      721 ttctacaata cgtagagaaa ccaagtctgc ctcttccgta cttgcatcaa tagtatggtg
      781 ataagccgtt gcatcctcat aaacctgctc ataagtcagt tctccccggg actgtttctc
      841 agccaaagat tccatatacg ctgatggcac tagattgtca actttctgca gaccaaaacc
      901 tatccgccat aaatcacgct tcgcttcata agacaagttt ggattgtcaa tgttgtaagt
      961 tgattgcata gaaatatcct ttcaattgtt tttcttcatt accagtaaat cacgaaattg
     1021 gttggaaact ggcttaaact ataaaaagtc ctcacaatag gttctatgat atatatatac
     1081 ttcatgtaaa taataaaaga gttataatca gcactactga taaattcaat accgatttcg
     1141 ccatcttaaa acttagtcaa acgaataccg ttgatttcca gttcattaag tcgttgacct
     1201 gtcaagactt ctcgttcctt caactggaaa agttaagggg gaactaatac aaatcctcta
     1261 cgcttctata ttcaatgatt tcatttttta taatattctt tttaaactca aaatgtttta
     1321 gaggattatc aactaatact aactttggaa tatcatctag gttggtgacc agagataaaa
     1381 taaaatctga ttgaaactct ttagctttct caaattcgta ggcagttaaa cggacacgac
     1441 ccttaggttt tcgaatccct ttaacttcgg caaggtagga atgttcttga atatctactt
     1501 ggaaatcata tccatcacca taaagacatg catcggttaa ctgtccacct tgaaattttt
     1561 cttctttatc aaaatgaagg ataaaataat tctctgcctc catccccgtt tcctgtagac
     1621 gtttgaattt agttcgaata attggttttt caattatagt aatgcctgtt tgctttcctt
     1681 cactagcaag taacatttta acaatttcaa cataactatg aacatcttca tttccaaaca
     1741 tcatatcaat taaatcttta cgaaaacggt aaacttcagc tttctgccac caaccttttc
     1801 gactattgtc aaaataagga tcaaataaat ccattctatt ttttacaact ccagttgttt
     1861 cagcaattcc caaagaaacc acatagcgat aaaactccga cttactagaa tattgaaatt
     1921 cttttataaa aagcttggca aacttggcaa gaccgtagcc aattaaattt aacaattcat
     1981 aatgcgggtg tttagacatc actttctcca tcaatagata gtaatttcat tatcccaaaa
     2041 aacacggcat tacaccatgt ttctgtgttt atttcaccaa cttcttcatc tcatcaatac
     2101 gtgctacggt cgcatcatac ttggcttggt agtcagcttg tttgtcgcgt tctttttgga
     2161 cgacttctgg tttggcgttg gctacgaagc gttcgttaga gagcttctta ccgaccatgt
     2221 ccagttcttt ttgccattta gcaagttcct tgtcaagacg agccagttct tcttcgacat
     2281 tgaggaggtc agccaatggc aggtagattt ctgctcctgt aatgacgctt gacatagcca
     2341 gttcaggtgc agggatggtt gatgcgattt ccaagtgttc tggatttgta aagcgtttga
     2401 tatagttgac attgctgtta aagaaggctt ccaagtcgct atcgcttgtc ttaacaagga
     2461 tggtgatagg cttgcttggt gctacgttta cttccgcacg cgcattacga acggcacgga
     2521 tcaagtcttt gagactttct acaccagtat gagccgcaag gtcttcaaag gctagattaa
     2581 cagttgggta tgcagctgtc acgatagaac cttctgagat ttgtccaaag atttcctctg
     2641 tcacgaatgg catgattggg tgaaggagac gaaggatctt gtccagagtg taaaggagaa
     2701 cagatcgagt aatgacctta tcgtcttcat tgtcgctgta aaggacttcc ttggtcaatt
     2761 caacatacca gttggcaaat tcttcccaaa tgaagttgta aaggatatga ccagccacac
     2821 caaactcgaa cttatcaaag ttttcagtaa cttttgcaat ggtttcgttg agattgtgga
     2881 gaatccagcg gtccgtcaca ttaccagcct cacctgttgc aacttttgtg acattgtcat
     2941 gcgccacatc cagcgtcaaa ccttcattgt tcatgaggat atagcgagaa atgttccaaa
     3001 ttttgttaat aaagttccat gaagcatcca ttttctcgta agagaaacga acgtcttgac
     3061 caggagctga gccgtttgac aagaaccaac gaagactatc tgtaccatat ttatcaataa
     3121 catccattgg gtcaatgcca tttccaagag atttagacat cttacgtcct tcttcatcac
     3181 gaattagacc atggataagg acgttttgga atggttgacg gcctgtgaat tccaatgact
     3241 ggaagatcat acgagacacc cagaagaaga tgatgtcgta acctgttacc aaggttgaag
     3301 ttgggaaata acgtttaaag tcttctgagt caacttcagg ccagcccatg gttgaaaatg
     3361 gccagagggc agaactgaac caagtatcca agacgtcttc gtcctgagtc catccgtcac
     3421 cttctggagc ttcttcgccg acatacattt caccatcagc attgtaccag gcagggattt
     3481 ggtgacccca ccaaagctga cgagagataa cccagtcgtg gacattttcc atccattgaa
     3541 ggaaggtatc gttgaaacga ggtgggtaga attcgacctt gtcctctgtg tcttggttgg
     3601 caatggcgtt cttagccaat tggtccatct tgacgaacca ttgagtagac aagcgtggct
     3661 caactacgac acctgtccgt tctgagtgac cgactgaatg gacacgtttt tcgattttga
     3721 caagggcacc gatttcttcc aacttagcaa cgactgcctt acgagcttca aaacgatcca
     3781 tgcctgaaaa ttcaaaggca agctcattca tagttccgtc gtcgttcatg acgttgactt
     3841 gtggcaagtt atgacgttgg ccaaccaaga agtcatttgg atcgtgggca ggtgtgattt
     3901 tcacgacacc agtaccaaac tcaggatctg cgtgctcatc tccaacgatt gggatgagtt
     3961 tattagcgat tggaaggatg acgtttttac caatcaagtc cttgtagcgc gggtcttctg
     4021 gattaaccgc aaccgcaacg tccccaaaca tagtctcagg acgagttgta gcaacttcaa
     4081 gggcgcgtga accatcttcc agcatgtagt tcatgtggta gaaggcacct tcgacatcct
     4141 tgtgaatcac ctcaatatca gaaagggctg tgcgagctgc tgggtcccag ttgatgataa
     4201 actcaccacg gtagatccag cctttcttgt aaaggtccac aaagacctta cgaacagctt
     4261 ttgacaaacc ttcgtcaaga gtgaaacgct cacgagagta gtctacagag agccccatct
     4321 tgccccattg ttccttgata gtagtggcat attcgtcttt ccattcccag actttcgtca
     4381 agaaagactc acgaccaagg tcatagcggg aaatgccctc accacgcaag cgctcctcta
     4441 ccttagcctg agtggcaatc cctgcgtggt ccatcccagg aagccaaagg gtatcaaaac
     4501 cttgcatgcg tttttgacgg atgataatat cttgcaaagt tgtatcccaa gcgtgaccaa
     4561 ggtgaagttt acctgtaacg tttggtggtg gaataacgat tgaataaggc ttagcctttt
     4621 gatcgcctga aggcttgaaa acatcagcat caagccattt ttggtaacga ccagcctcaa
     4681 cctcggctgg attgtattta gatgaaagtt ctttagacat gtgtgtgtcc tttctctatt
     4741 ttgtttattt tattttgaat ttgcttagca gcttcttctg cagacaaatt cgtattattt
     4801 attttaaagt agtggtgcaa ctcattcggt tgatattggg aatttaattg aagtgtttca
     4861 gcggtctcta aaatttctct ttcagatacc tcaatatgtc gttttaaggg tttgtgcttt
     4921 aatcgattct ccgttcgatt tcgacgtatg cactcttcaa gacttgtttc caactcaaca
     4981 aaaagaatct cttgatgata atcatccaac aaattctgaa tttgctttaa atatatcaga
     5041 tgatactgat ttgaaaaatc aattacatct gttaaaatta ctgatcgctg atttcttgca
     5101 cttgctccaa ggaatgaaaa agtgattcca cgaacaaatt cccacatttc ctctgtatag
     5161 tcctgataga tttctagtgc aaaatcaatg gcttgatggt tataaaatag ggtagcatcc
     5221 gtcagtcgag ataattcttg accaatggtc atttttcctg atgctggagc accaatgatg
     5281 aaaagatgca tcaaatcacc ccccactcac tcttcagcaa ggcatatctc aaatcatcac
     5341 agcagttgcc ttgagcatct ttacggtctc ttatgcgagc ttcgagggta aagccaagct
     5401 tttccgcgac tcgttgactt tgaaggttat atccaaagca agttagttca atcttgtgaa
     5461 gacccaaatc tttaaaggct aagtcaatca aggcacgcgc agcttctggc acataacctc
     5521 gcccccaata gtctgagtgt aaggtatagc cgatttccat cacatcatct tcatggcgat
     5581 ggttgaaata gatagagcca acgatcttat ccgttccttt gacgacaatc ccgtagcctg
     5641 ctgggagatt ttccttttga ttacgctccg gaagaatgtg ctccagataa taaatctcat
     5701 cttccaaggt cttgactgga ggaaaacctg ctggataggc gacctctggc aaactagcat
     5761 agtcaaagat atcctcagca tccgccacag tacggactcg taaaacgaga cgttctgttt
     5821 cgattttatc tggcagctca gttcttgcca tccttcttcc tcgctttttt gatgaaactg
     5881 cccttcatat ctacacgctt gtccagatag cgataaacgc gctgatatcc atctcccatg
     5941 aaataggttg gggcaaacag ttgattttta aaatgtccct tttcatccag gagttctggg
     6001 gcaacaagtc gctcaagaat cttggcaaag atgtggcaaa taccgtcttc ctcaacaatc
     6061 ctatctaccc gacaatctaa aacaagtgga caggcgtcta aaataggagt ctgagttcgt
     6121 tcagaaattt cataatgcac tcccaaacgt tccaatttct cctgatgact gataaaacca
     6181 gcctgctcca tcgcaagcat agaagtttca tcagaaatat tcacagtaaa tttttgatac
     6241 tgtttgatct gctctgcggc attctctctc gcaacgactc caatcacaac ccaatctcct
     6301 agactataag aggaactaca ggtcgtgatg ttatagccaa aattctaatc ttgatatcct
     6361 aaaataaaaa caggaaaacc ataatatagt ttacttgtgt taaaagattg cttcataaca
     6421 accccctttg actaagacgt aaaagaaaag ccctgccatc tacatgacag ggacgaatgt
     6481 gtttatccgc ggtaccaccc aatttcgggc agttgcccgc aactctcgtc tttaaagcaa
     6541 aaagacactt ttatttcaat ttttcatcca ttagcaacca gttttgacac atttgtggac
     6601 ttctcagcgc cgccactttc tgtaaaatgt gggattcaaa acacctctaa tggctctatt
     6661 gtagcaagat tttttcggaa atgcaaggct caagaaaaat tacttgaact tgatgccatt
     6721 ttctttcaat ttcttgatgg tagctgggcc gattcctttc aagtcaagga gttctttttc
     6781 agtccagttt ttgaaatgtg aagcagactt gattccttca tcatagaaag tcttggcacg
     6841 atcaagtgga agtccaccca aatttgctgc aaaatcttct acagaattag ctactttttg
     6901 agcttgctct ttggtagctt ctactgcttg ttcaactttt ttagaaacag ccttaccagc
     6961 tgcgcttgct gtctgttctg cacgcttcac gacttttttt gtctcatcta caaccttagt
     7021 cacagtactt gaaaaggcac ctgcgcgacg gaggccattt cgtaattgtt ttttacgatt
     7081 gagtttcttt gacatgataa aatcctttca ataaaaaatc cctgctctga caaggattta
     7141 acataaacat tctatcaaga ttttagtgaa aaatcaagaa tctttctcgt ttaataattt
     7201 cgctcaccaa acaagccttc tggcaaatca tggaatccct tgcctacttt gaagttttca
     7261 aacttaccaa gcaagaactg ataagcatcc aagcgactct cgtagcgaat catggcatct
     7321 ttggcacgct cgtcctggtc ttcttcgtaa actttttgac tttccttgtg cgccatatcg
     7381 ttaatcatga tttgggtatt gacccaagct tcaaattcct tcataaattc ttgttcgtaa
     7441 ctcatttttt ctccttattc taatccacga aaatagtccg tatcaatctc acggtagggc
     7501 tggatatcct gaacatactc caacactcct tggaattctc cgtcttcatc gtgtactgca
     7561 gcataggtga tgtggacaaa cttacctcgc gactcagact tgaaccacat ttcatacttg
     7621 tccttggtcc cctcacgaag tcccttcatg atagccttga ccttgtccaa atacttaggc
     7681 ggatgacaga gttcgacatt gcgcccgact tgggacggcg tccgtttgaa aatcatctca
     7741 tcagctggcg tattgtcatt gtaatactgg aaaatatctt ctttattgac aaaggtaatc
     7801 tccataggga gatgattgag gatgagattg gcctgctcga ctgaaagata gccattacca
     7861 aaagcctgtt gactatggcg gtccagcaca gcttcctttt ccttaggggt aaaggtaatg
     7921 gtaaaatggc cttctggcgt atctatgact tgttgaactt gaccttctgc cgtatctagt
     7981 tgtacaggct cctctgcaat cttttcctca ataaagatct gtcgttctgg cacccatttc
     8041 tctgacggac ggatgatggc atagccatag gcatcactct cctccgcaat ctgaagccag
     8101 tcatcctgag taaaagactc aaggagaatc atgagcagga tggactcttc cttgaaaatc
     8161 atactttcaa actctgtcgc aaaagcttca aaagcttcct ttacactgct aattgacact
     8221 tctggtagtg acttggctgt cgttagagct gtttgaaaga gttccctaat ctgatcatcc
     8281 actccccaca taactttggg aggtgaatcg tgtccatagc gctccatgat aggaaagaag
     8341 agttcttcct tacgttggta atggatgtca aattgaccca caagtcccat ctgacgcacc
     8401 aaacccttac gcatctccgc cagcatttcc tcgtcttcca tagactcata ggtatctaac
     8461 aatctacgaa tgcgaatcaa ggccgcacgg agagccagat tttcttcttt gaagacacga
     8521 actgggtgac ctggatgctc agtatctgaa acttcgacac ctttgatagc atttttaaaa
     8581 agattggcat ggacatcaca gagttccata acatcttcaa aagtgacgcc cgaatccgag
     8641 ttcatcagct cgtgctccat aagggaaatc tcaatggctg agacacccgc aaaggtcgca
     8701 tcaaaacgct cctgaaccga ctcaggagag gcgccattat gcaattctaa taaaatatcc
     8761 cgtaggacat gaatccgttc atctgccatt agtctaatcc aatcacttcg tagccattcg
     8821 cttccagtgt gcgtacaatc ttgtccatag gagttcctgc tagcttagaa ccctgtttaa
     8881 gtgatacttt acgaccaact gtattgcgca ttaagggatt ggcaaggggt ttaaaaccca
     8941 actccactag aatttccaag acttctggat gcttgtccac cacttctgca acaggaattg
     9001 acacatcgat gatattgtcc atgacgacct ccattatatg ttctaatact caatgaaaat
     9061 caaagagcaa actaggaagc tagccgcagg ttgctcaaaa cagtgctttg agattgtaga
     9121 tagaactgac gaagtcagct caaaacaccg ttttgaggtt gcggatagaa ctgacgaagt
     9181 cagtaacata tatacagcaa ggtgaagctg acgtggtttg aagagatttt cgaagagtat
     9241 aaaatgattt tactgcttat attataccat atggaaagag aataaaaaac tagcagtgga
     9301 gttcctgcta gttctctgcg acttggatta ccatctagat aagtttaaag aaccaatcca
     9361 atatcttgta aaacagcaat tggactgcaa aagagatgat catccaaaag aatttcacaa
     9421 tcccaataat cggtttgata aaaataatgg caagaagtcc ccagaaaaat ttcatttttt
     9481 atcctctggc ttaatgagcc accgagccgt atccattaac ttgtcggcaa taaaaagttt
     9541 ccccagaccg acaacggcat tatcatcttt ctttatcgtt ttcattactt ttacaccttg
     9601 cacggtcaaa aagtaattac cataaatttt agcaaaagct ttgataggat tcatattact
     9661 ctcctttgat gatttcagcc tcttttcgga ttgtttcaac atcttcttga tattgaactt
     9721 cactatagtt gactagcttg gataattctt tctgcaagct ttcccccatt ggtttcatag
     9781 ttgcaaaggt taaaccacct gaaatgatac cacccaagat aggaataaat ttccccattc
     9841 ctttggccag ccctcccttg gtaagattca caccaaatat tcttaagact ttcttcaaaa
     9901 taggatacca aagcgtcttt gttaaagctt tattaggtac tgttttcatt acctgtttgg
     9961 caattgttat accaccagca cgtagcaaag cagcagttcc attcaccccc aacatgacgc
    10021 ctagataaag caaaagggta ttttgagcat cttcactcaa ctcatcgcgt gaagcccaaa
    10081 gatcctcata accataaata taacctaatt cttgggccaa tttcagagag aaaccataaa
    10141 attgagccac atcagctgga atggtaattg ccatagcaag ccctccaggt aatcctgcca
    10201 aaacagaagt cccactcgct aataaaacat tatccctaat acaggcatta gccactcgat
    10261 ctaagatttc ttgagataag agagacgttg gaccttgttc caataaggta ggaatgtcct
    10321 gtggacccaa ttctttggaa aacttatcca ctaaaaattt cgaacgatca accttaacaa
    10381 caggtagttt caccacttgt tgcaatactt gcatagctaa gtcttgttca gccatataca
    10441 aactccttat ttcttttttg caccttatca tattatattt cctacaaaaa aagcattttc
    10501 taattagata acattaaaaa atacagaacc ccttttttat agtaaaatga aacaagaaca
    10561 ggacaaatcg atcaggacag tcaaatcgat ttctaacaat attttagaag tagaggcgta
    10621 ctattctagt ttcaaactat t
//
LOCUS       DAVBOG010000064        10624 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.064, whole genome shotgun sequence.
ACCESSION   DAVBOG010000064 DAVBOG010000000
VERSION     DAVBOG010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10624)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10624)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10624
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.064"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            389..1567
                     /locus_tag="VQ865_001892"
     CDS             389..1567
                     /locus_tag="VQ865_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000071468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HET3136191.1"
                     /translation="MSNSFVKLLVSQLFANLADIFFRVTIIANIYIISKSVIATSLVP
                     ILIGISSFVASLLVPLVTKRLALNRVLSLSQFGKTILLAILVGMFTVMQSVAPLVTYL
                     FVVAISILDGFAAPVSYAIVPRYATDLGKANSALSMTGEAVQLIGWGLGGLLFATIGL
                     LPTTFIILVLYIISSFLMLFLPNAEVEVLESETNLEILLKGWKLVARNPRLRLFVSAN
                     LLEIFSNTIWVSSIILVFVTELLNKTESYWGYSNTAYSIGIIISGLIAFRLSEKFLAA
                     KWESILFPLVAMAIVTLTILYFPNAQMFLLFSALVGMLSQLKEVPESVFLQETVEENH
                     LVNVYSVLEVISTLAFSVFVLLMSYITESFGISISFWLSAICLMIEAILIYIRRDYFK
                     "
     gene            1881..2012
                     /locus_tag="VQ865_001893"
     CDS             1881..2012
                     /locus_tag="VQ865_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000813667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HET3136192.1"
                     /translation="MKQRKELYLFLGRTALYFLIFLGLLYFFSYLGQGQGSFIYNEF"
     gene            2033..3583
                     /gene="dltA"
                     /locus_tag="VQ865_001894"
     CDS             2033..3583
                     /gene="dltA"
                     /locus_tag="VQ865_001894"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012972622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HET3136193.1"
                     /translation="MSNKPIADMIETIEHFAQTQPSYPVYNVLGQEHTYGDLKADSDS
                     LAAVIDQLGLPEKSPVVVFGGQEYEMLATFVALTKSGHAYIPIDSHSALERVSAILEV
                     AEPSLIIAISAFPLEQVSTPMINLAQVQEAFAQGNNYEITHPVKGDDNYYIIFTSGTT
                     GKPKGVQISHDNLLSFTNWMITDKEFATPSRPQMLAQPPYSFDLSVMYWAPTLALGGT
                     LFTLPSVITQDFKQLFAAIFSLPIAIWTSTPSFADMAMLSEYFNSEKMPGITHFYFDG
                     EELTVKTAQKLRERFPNARIINAYGPTEATVALSAVAVTDEMLATLKRLPIGYTKADS
                     PTFIIDEEGNKLPNGEQGEIIVSGPAVSKGYMNNPEKTAEAFFEFEDLPAYHTGDVGT
                     MTDEGLLLYGGRMDFQIKFNGYRIELEDVSQNLNKSRFIESAVAVPRYNKDHKVQNLL
                     AYVILKDGVREQFERDIDITKAIKEDLTDIMMSYMMPSKFLYRDSLPLTPNGKIDIKG
                     LINEVNKR"
     gene            3580..4824
                     /gene="dltB"
                     /locus_tag="VQ865_001895"
     CDS             3580..4824
                     /gene="dltB"
                     /locus_tag="VQ865_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000969717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HET3136194.1"
                     /translation="MMEFFQQLPHLEPYGNPQYFVYVIAATLPIFIGLFFKKRFAWYE
                     VLVSLFFIVTMLVGGKTNQLAALGIYLCWEILLLLFYKHYRKSKDGKWVFYLVSFLSL
                     LPIIFVKVQPAINGTQSLLGFLGISYLTFRSVGIVIELRDGVIKDFTLWEFLRFLLFM
                     PTFSSGPIDRFKRFNENYQAIPERDELMDMLDESVRYIMWGFLYKFILAHVLGETLLP
                     PLKNLALQSGGFFNLYALAVMYTFGLELFFDFAGYSMFALAISNLMGIRSPINFNKPF
                     LSRDLKEFWNRWHMSLSFWFRDFVFMRMVMVLTRKKVFKNRNVTSSMAYIVNMLIMGF
                     WHGVTWYYIAYGLFHGLGLVINDAWVRKKKTLNKERKKAGKAALPENRWIQLLGMVVT
                     FHVVMLSFLIFSGFLNNLWFKK"
     gene            4838..5077
                     /gene="dltC"
                     /locus_tag="VQ865_001896"
     CDS             4838..5077
                     /gene="dltC"
                     /locus_tag="VQ865_001896"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005591431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HET3136195.1"
                     /translation="MDIKSEVIEIIDELFMEDVSDMMDEDLFDAGVLDSMGTVELIVE
                     IENRFDIRVPVTEFGRDDWNTANKIIAGIVELQNA"
     gene            5070..6338
                     /gene="dltD"
                     /locus_tag="VQ865_001897"
     CDS             5070..6338
                     /gene="dltD"
                     /locus_tag="VQ865_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000919885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HET3136196.1"
                     /translation="MLKRLWMIFGPVLIAGLLVFLLIFFYPTEMHHNLGAEKRSAVAT
                     TIDSFKERSQKVRALSDPNVRFVPFFGSSEWLRFDGAHPAVLAEKYNRSYRPYLLGQG
                     GAASLNQYFGMQQMLPQLENKQVVYVISPQWFSKNGYDPAAFQQYFNGDQLTSFLKHQ
                     SGDQASQYAATRLLQQFPNVAMKDLVQKLASKEELSTADNEMIELLARFNERQASFFG
                     QFSVRGYVNYDKHVAKYLKILPDQFSYQAIEDVVKADAEKNTSNNEMGMENYFYNEQI
                     KKDLKKLKDSQKSFTYLKSPEYNDLQLVLTQFSKSKVNPIFIIPPVNKKWMDYAGLRE
                     DMYQQTVQKIRYQLESQGFTNIADFSKDGGEPFFMKDTIHLGWLGWLAFDKAVDPFLS
                     NPTPAPTYHLNERFFSKDWATYDGDVKEFQ"
     gene            6493..6933
                     /gene="adcR"
                     /locus_tag="VQ865_001898"
     CDS             6493..6933
                     /gene="adcR"
                     /locus_tag="VQ865_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001249319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-dependent transcriptional regulator AdcR"
                     /protein_id="HET3136197.1"
                     /translation="MRQLAKDIDAFLNEVILQAENQHEILIGHCTSEVALTNTQEHIL
                     MLLSEESLTNSELARRLNVSQAAVTKAIKSLVKEGMLETSKDSKDARVIFYQLTDLAR
                     PIAEEHHHHHEHTLLTYEQVATQFTPNEQKVIQRFLTALVGEIK"
     gene            6933..7637
                     /locus_tag="VQ865_001899"
     CDS             6933..7637
                     /locus_tag="VQ865_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HET3136198.1"
                     /translation="MRYITVEDLSFYYDKEPVLEHINYCVDSGEFVTLTGENGAAKTT
                     LIKASLGILQPRIGKVAISKTNTQGKKLRIAYLPQQIASFNAGFPSTVYEFVKSGRYP
                     RKGWFRRLNAHDEEHIKASLDSVGMWEHRDKRLGSLSGGQKQRAVIARMFASDPDVFI
                     LDEPTTGMDAGSKNEFYELMHHSAHHHGKAVLMITHDPEEVKDYADRNIHLVRNQDSP
                     WRCFNVHENGQEVGHA"
     gene            7630..8436
                     /locus_tag="VQ865_001900"
     CDS             7630..8436
                     /locus_tag="VQ865_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HET3136199.1"
                     /translation="MLSLLSYDFIQRAFLAVIAMSLFSPVLGTFLILRRQSLMSDTLS
                     HVSLSGVAFGLVLGISPTVSTIAIVLIAAVFLEYLRTVYKSFMEIGTAILMSTGLAVS
                     LIVMSKGKSSSSMSLDQYLFGSIVTISEEQVISLFVIAAVVLILTFLFLRPMYILTFD
                     EDTAFVDGLPVRTMSILFNMVTGVAIALMIPAAGALLVSTIMVLPASIALRLGKNFKS
                     VMLLASAIGFLGMVAGLYISYYAETPASASITIIFVTVFILISLVRRFIK"
     gene            8446..9951
                     /gene="adcA"
                     /locus_tag="VQ865_001901"
     CDS             8446..9951
                     /gene="adcA"
                     /locus_tag="VQ865_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding
                     lipoprotein AdcA"
                     /protein_id="HET3136200.1"
                     /translation="MKKISLLLASLCALFLVACSNQKQADGKLNIVTTFYPVYEFTKQ
                     VAGDTANVELLIGAGTEPHEYEPSAKAVAKIQDADTFVYENENMETWVPKLLDTLDKK
                     KVKTIKATGDMLLLPGGKEEEGDHDHGEEGHHHEFDPHVWLSPVRAIKLVEHIRDSLS
                     ADYPDKKETFEKNAAAYIEKLQALDKAYAEGLSQAKQKSFVTQHAAFNYLALDYGLKQ
                     VAISGLSPDAEPSAARLAELTEYVKKNKIAYIYFEENASQALANTLSKEAGVKTDVLN
                     PLESLTEEDTKAGENYISVMEKNLKALKQTTDQEGPAIEPEKAEDTKTVQNGYFEDAA
                     VKDRTLSDYAGNWQSVYPFLEDGTFDQVFDYKAKLTGKMTQAEYKAYYTKGYQTDVTK
                     INITDNTMEFVQGGQSKKYTYKYVGKKILTYKKGNRGVRFLFEATDADAGQFKYVQFS
                     DHNVAPVKAEHFHIFFGGTSQEALFEEMDNWPTYYPDNLSGQEIAQEMLAH"
BASE COUNT         3056 a         2002 c         2251 g         3315 t
ORIGIN      
        1 actcccctga aatttatttt aattatgcaa atttcacgta tttttgatgc tgagacgacg
       61 atcctgggaa cttttcagat atttttttga ctatctaaat ctatcattag aaaagcttag
      121 agcgccaaag gatttgagcg tttttctgat ttttaagact ttttccagtc tctttttcga
      181 ttgaagatgt aattattcta ctaactaact aacttcttag tactagccaa caacgataat
      241 cataattcct cctaaaatta ggaataataa aggcaatagt ttttgttttt tcatgtaaaa
      301 aacctcactt ttgttttctg ctattttatg ctaaaatatt aaaaatcaaa tttaattcca
      361 aagtttgtaa ctaaaggggg agcgctacat gtctaattca tttgtcaagt tgttagtctc
      421 tcaattattt gcaaatttag cagatatttt ctttagagta acaatcattg ctaacatata
      481 cattatttca aaatcagtaa ttgccacatc actagttcct atcttaatag gaatatcctc
      541 ttttgttgcg agtcttttag ttccgttggt tactaaaagg ttagcgctaa atagggtttt
      601 atctttatct caatttggaa agactatatt attggcgata ctggtaggaa tgtttaccgt
      661 aatgcaatcc gtagcgcctt tggtgaccta tctatttgtt gttgcaattt ccatactaga
      721 tggttttgca gcacccgttt cctatgctat tgtgccacgc tatgcgaccg atttgggtaa
      781 ggctaattca gccttatcaa tgactggtga agctgttcaa ttgataggtt ggggattagg
      841 tggactcttg tttgcaacaa ttggtctgtt acctaccacg tttatcattt tagtcttgta
      901 tatcatttct agctttctga tgttatttct tcctaacgct gaagtggagg tgttagagtc
      961 agaaactaat cttgaaattt tgctcaaagg ttggaagtta gttgctagaa atcctagatt
     1021 aagacttttt gtatcagcaa atttattgga aattttttca aatacgattt gggtttcttc
     1081 cattatactt gtttttgtaa cggagttatt aaataaaacg gaaagttact ggggatattc
     1141 taatacagca tactctattg gtattataat tagtggctta attgctttta ggctatctga
     1201 aaagttcctt gctgctaaat gggaaagtat tctttttcct cttgtagcta tggcaatagt
     1261 gacactgact attctatatt ttccaaacgc acagatgttt ttattatttt cagctttagt
     1321 tggtatgtta tcgcaactaa aagaagttcc tgaaagtgta tttcttcagg aaacagtaga
     1381 ggaaaatcat ttagttaatg tctattccgt tcttgaagtg atttctacat tagcattttc
     1441 agtatttgtt ttgctaatga gctatattac tgagagtttt ggtattagca tcagtttttg
     1501 gctatcagcc atttgtctga tgatagaagc tattttaatt tatatcagac gagattattt
     1561 taaatgagag agtggttaaa aagtctttaa aaatcagaaa agcgcatagt atcaggtgtt
     1621 gaaaaaactt gatattgtgt gttttattat gggaagattt acttcattgt ctcctgaaat
     1681 ggagttttga ggcaggatca ctctatttga aaatatacat agaaaaactg tataatcctt
     1741 aaaataagct gaaatctatt ggaaacatac ggtaaacaat tgaaaagata ctatataaag
     1801 tggtacaatg gtagaaaaat aagctagtaa gaatcactct tattttagcg aaaaattaca
     1861 gaaatgaatg gtttttcttg atgaaacaga gaaaagaatt gtacctcttt cttggtcgga
     1921 cagccttgta ttttcttatc tttctagggc tgctttactt ctttagctat cttggtcagg
     1981 gtcaaggaag ctttatctat aatgaatttt aacttgaagg agaatcccta ttgtgtcaaa
     2041 taaaccaata gcagatatga ttgaaaccat tgagcatttt gctcagacac agcctagcta
     2101 tcctgtctat aatgttttgg ggcaggaaca cacttatggc gatttaaagg ctgattcgga
     2161 tagtttggct gcagtcattg accaactagg cttgcctgag aagtctcctg tggttgtttt
     2221 tggtggccaa gaatatgaaa tgttggcaac ctttgtagcg ctgactaagt caggtcatgc
     2281 ctacattcca attgatagcc attcggcctt ggagcgagtt tcagctattt tagaagtagc
     2341 agagccaagc ttgattattg ccatttcagc ctttcccttg gagcaggttt ctacaccaat
     2401 gataaatcta gctcaggttc aagaagcctt tgcccaaggg aataactatg aaatcacgca
     2461 tccagtcaag ggagatgata attactacat tatctttact tctggtacga ctggtaagcc
     2521 taagggagtg cagatttcac atgataatct cctcagcttt acaaactgga tgattacgga
     2581 taaggaattt gcgacaccga gtcgtccgca aatgctggca cagccacctt attcttttga
     2641 cttgtctgtc atgtattggg caccgacctt ggcacttggt ggtacgcttt tcactcttcc
     2701 ttcagtcatc actcaggact ttaagcaact ctttgcggct atcttttcat tgccaatcgc
     2761 tatctggaca tcaacaccat cctttgcaga tatggccatg ttgtctgaat acttcaacag
     2821 tgagaaaatg cctggaatca cgcatttcta ctttgatggt gaagaattga cggtcaaaac
     2881 agctcaaaaa ctgcgcgagc gtttcccaaa tgcccgtatc atcaatgctt acggcccaac
     2941 agaagcgaca gtagctctgt cagcagttgc cgtgacagac gagatgttag cgactctcaa
     3001 acgcctacca atcggctata ccaaggctga ttctccaacc tttatcattg acgaggaagg
     3061 aaataaactg ccaaatggtg agcagggaga aatcattgtt tctgggccag ctgtttcaaa
     3121 aggttatatg aacaatcctg aaaaaacagc agaagccttc tttgagtttg aagatctgcc
     3181 agcctatcac acaggcgatg tgggaaccat gacagatgag ggcttgcttc tctacggcgg
     3241 acgcatggac ttccagatta agtttaacgg ttaccgcatt gagttagaag atgtctctca
     3301 aaacctcaac aagtctcgct ttatcgaatc tgctgtcgca gtaccgcgct ataacaagga
     3361 ccacaaggta caaaatctat tggcttatgt catcttaaaa gacggtgttc gtgagcagtt
     3421 tgagcgagat atcgatatta ccaaggccat caaggaagac ctgacagaca tcatgatgtc
     3481 ctatatgatg ccatctaaat tcctttaccg agacagtttg ccactaactc caaatggaaa
     3541 gattgacatc aaaggattga ttaacgaggt gaataagaga tgatggagtt ttttcaacag
     3601 cttcctcatt tagagccata tggcaatcct cagtattttg tttatgtgat tgctgcaacc
     3661 ttgcccatct ttataggtct ctttttcaag aaacgctttg cctggtatga agtgttggta
     3721 agtctcttct ttattgtcac catgttggtg ggtggaaaga ccaatcaact agctgccttg
     3781 ggtatttacc tttgctggga aatattgctc ctgcttttct acaagcatta tcgaaaaagc
     3841 aaggatggca agtgggtctt ctacttagtt agttttctgt ccctacttcc gattatcttt
     3901 gtcaaggtgc aaccagctat caatggaacg cagtctttgc ttgggttctt gggaatttct
     3961 taccttacct ttcgttcggt tgggattgtc atcgagctga gagatggagt gattaaggat
     4021 tttaccctct gggaattcct ccgtttcctt ctcttcatgc caactttctc gagtggtcca
     4081 atcgatcgct ttaagcgatt taatgaaaat tatcaggcta ttcctgagcg agatgagttg
     4141 atggatatgc tggatgaatc tgtccgctat atcatgtggg gctttttgta taagtttatc
     4201 ctagctcatg ttttaggaga gaccttacta cctcctctga agaatttagc cttgcagtca
     4261 ggtggcttct ttaatctcta tgccttggca gttatgtata cttttggtct ggaactcttc
     4321 tttgactttg caggttattc tatgtttgct ttggccatct caaacttgat gggaatccgt
     4381 agccctatca actttaacaa gcccttttta tcaagggatt taaaggagtt ttggaatcgc
     4441 tggcatatga gtctgtcctt ctggttccgt gactttgtct ttatgcgaat ggtgatggtg
     4501 ttaaccagaa agaaagtctt taaaaatcgt aatgtaacct caagcatggc ctacattgta
     4561 aatatgctga ttatgggatt ttggcatggt gtgacctggt actatatcgc ctatggactc
     4621 tttcatggac taggcttggt catcaatgat gcctgggttc gcaagaaaaa aacgctcaat
     4681 aaggaacgga aaaaagcagg gaaggctgcc ctacctgaga atcgctggat tcagttgctt
     4741 ggcatggttg tcactttcca tgttgtcatg ttgtcattct taatcttttc tggattcttg
     4801 aataatctat ggtttaaaaa ataaaaggaa ataaaatatg gatatcaaat cagaagttat
     4861 tgaaattatt gatgagttgt ttatggaaga tgtttctgac atgatggatg aagatctttt
     4921 tgatgcaggt gtcttggata gtatgggaac ggttgagttg attgtggaga ttgagaaccg
     4981 ttttgacatt cgtgtccctg taacagagtt tggtcgtgac gactggaata cagctaataa
     5041 aatcatagct ggtattgtgg agctacaaaa tgcttaaacg cttatggatg atcttcggac
     5101 cggtcttgat cgctggtttg ttggtttttc tgctcatttt cttttatcct actgagatgc
     5161 atcataatct aggagctgaa aagcgttcag cagtggctac tactatcgat agttttaagg
     5221 agcgaagtca aaaagtcaga gcactatctg atccaaatgt gcgttttgtt cccttctttg
     5281 gctctagtga atggcttcgt tttgacggtg ctcatcctgc ggtattagct gagaaataca
     5341 atcgttccta ccgtccttat cttttaggac aggggggagc tgcatcgctt aaccaatatt
     5401 ttggaatgca acagatgtta ccacagctgg agaataaaca agttgtgtat gttatctcac
     5461 ctcagtggtt cagtaaaaat ggctatgatc cagcagcctt ccagcagtat tttaatggag
     5521 accagttgac tagttttctg aaacatcaat ctggggatca ggctagtcaa tatgcagcga
     5581 ctcgcttact gcaacagttc ccaaacgtag ctatgaagga cctggttcag aagttggcaa
     5641 gtaaagaaga attgtcgaca gcagacaatg aaatgattga attattggct cgttttaatg
     5701 aacgccaagc ttcctttttt ggtcagtttt cggttagagg ctatgttaac tacgataagc
     5761 atgtagctaa gtatttaaaa atcttgccag accagttttc ttatcaggca atagaagatg
     5821 ttgtcaaagc agatgctgaa aaaaatactt ccaataatga gatgggaatg gaaaattatt
     5881 tctataatga gcagatcaag aaggatttga agaaattaaa ggattctcag aaaagcttta
     5941 cctatctcaa gtcgccagag tataatgact tgcagttggt tttaacacag ttttctaaat
     6001 ctaaggtaaa cccgattttt atcattccac ctgttaataa aaaatggatg gactatgctg
     6061 gtctacgaga ggatatgtac caacaaacgg tgcagaagat tcgctaccag ttggaaagtc
     6121 aaggttttac caatatagca gatttttcta aggacggcgg ggagcctttc tttatgaagg
     6181 acaccattca ccttggttgg ttgggttggt tggcttttga caaggcagtt gatcctttcc
     6241 tatccaatcc cacaccagct ccgacttacc atctgaatga gcgctttttc agcaaagatt
     6301 gggcgactta tgatggagat gtcaaagaat ttcaatagat aatataatat agaagagttc
     6361 aagaatgaaa ctagttttca cgttttttct tgactctttt tttgcttgtg atataattaa
     6421 ctggtaaaca aaatgtcaaa gaatagtatt tttctcttaa aaaagagaag tctaaaagga
     6481 aaggagtcag atatgagaca gctagcaaag gatatcgatg cttttttgaa tgaggtgatt
     6541 ttgcaggcgg aaaatcagca tgaaatccta ataggtcatt gcactagcga ggtggccctg
     6601 accaatactc aggagcatat ccttatgctc ttgtcagagg aatctttaac aaattcagaa
     6661 ttggcccgtc gtctcaatgt cagtcaggcg gcagttacca aggccattaa gtctttggtc
     6721 aaggaaggga tgttggaaac atctaaagat tctaaagatg cgcgtgtgat tttttatcag
     6781 ttgactgact tggctcgtcc aatcgctgag gagcaccacc atcaccatga gcatacactt
     6841 ttaacctatg aacaagtggc gactcagttt actccaaatg aacaaaaagt gattcagcgg
     6901 tttttgactg ctttagtagg agaaatcaaa taatgagata tattacggta gaggatttgt
     6961 ccttctatta tgataaggag cctgttcttg aacatatcaa ttattgtgtt gatagtgggg
     7021 aatttgttac cttgactggg gaaaatggag cggctaagac gacgctcatc aaggctagtc
     7081 ttggaattct gcaaccacgc attggaaagg tggctatttc aaagacaaat acgcaaggta
     7141 agaaattgag aatagcctat cttcctcaac aaattgccag ttttaatgct ggttttccaa
     7201 gtacggtcta tgaatttgtc aagtcgggtc gctatccgag aaaaggctgg ttccgtcgtt
     7261 tgaatgctca tgatgaggag catatcaagg ctagtctgga ctcagttggc atgtgggaac
     7321 atcgagacaa acgcttgggg tctctatctg ggggacaaaa gcagcgagcg gtgattgcgc
     7381 gtatgtttgc ttctgaccct gatgtgttta tcctagacga gccgacaacg gggatggatg
     7441 caggaagtaa aaatgaattt tacgaactca tgcaccacag cgcccatcat catggcaagg
     7501 ctgttttgat gattacccat gaccctgaag aagttaagga ttatgcggat cgcaatattc
     7561 atctagtccg taaccaagac tcgccatggc gttgtttcaa tgttcatgag aatggccagg
     7621 aggtgggcca tgcttagttt attatcttac gactttatac aacgcgcctt tttggcggtt
     7681 attgctatga gtcttttctc accggtattg ggaaccttcc tcatcttgcg tcgtcagagt
     7741 ttgatgagtg atacccttag ccacgtctca ctttcaggtg tagcctttgg tctggttttg
     7801 gggatttctc caactgtttc tactattgcc attgtcttga ttgcggcggt ctttctggag
     7861 tatctccgta cggtttacaa gagctttatg gaaatcggga cagctatcct catgtcaaca
     7921 ggtctggctg tttctctgat tgtcatgagc aagggtaaaa gctcgagttc aatgagtttg
     7981 gaccaatatc tctttggttc gatcgtgact atcagtgaag aacaggtcat ttccctcttt
     8041 gtcattgcgg cggttgtttt gattttgacc tttctctttc ttcgtcctat gtatatctta
     8101 acttttgacg aagatacggc ctttgtggat ggcttgccag ttcgtaccat gtccattctt
     8161 tttaacatgg tgacaggggt ggctattgcc cttatgattc ctgcagcagg agctcttctg
     8221 gtatcgacca ttatggtctt gccagctagt attgccctgc gtctggggaa aaactttaaa
     8281 tcggttatgc tgcttgccag tgcgattggc tttttgggaa tggtagcagg actttacatt
     8341 tcctactatg cagaaacacc tgcaagtgca agtattacca ttatttttgt aactgtcttt
     8401 atactaatca gtttagtaag acgttttatc aaataggaga cgaacgtgaa aaaaattagc
     8461 ttattactag ccagtctatg tgccttgttt ttagtggctt gttccaatca aaaacaggca
     8521 gatggtaaac tcaatatcgt gacaaccttt taccctgtct atgaatttac caagcaagtc
     8581 gcaggagata cggctaatgt agaactccta atcggtgctg ggacagaacc tcatgaatac
     8641 gaaccatctg ccaaggcagt tgccaaaatc caagatgcag ataccttcgt ttatgaaaat
     8701 gaaaacatgg aaacatgggt acctaaattg ctagatacct tggataagaa aaaagtgaaa
     8761 accatcaagg cgacaggcga tatgttgctc ttgccaggtg gcaaggaaga agagggagac
     8821 catgaccatg gagaagaagg tcatcaccat gagtttgacc cccatgtttg gttatcacca
     8881 gttcgtgcca ttaaactagt agagcacatc cgcgacagct tgtcagcaga ttatcctgat
     8941 aaaaaagaga cctttgagaa gaatgcagct gcctatatcg aaaaattgca agccttggat
     9001 aaggcttacg cagaaggctt gtctcaagca aaacaaaaga gctttgtgac tcaacacgca
     9061 gcctttaact atcttgcctt ggactatgga ctcaaacaag tcgcaatctc aggactttct
     9121 ccagatgcag agccatcagc tgctcgcttg gcagaattga cagagtatgt caagaaaaat
     9181 aaaatcgcct atatctattt tgaagaaaat gcctcacaag cccttgctaa cacactttca
     9241 aaagaagcag gtgtcaaaac tgatgtcctc aatcctttag aaagtctgac agaagaggac
     9301 accaaggctg gagaaaacta catttccgtg atggagaaaa acctcaaggc tttgaaacaa
     9361 acaacagacc aagaaggccc agcaatcgaa cctgaaaagg cagaggatac caagacagtc
     9421 caaaatggtt acttcgagga tgcagctgtc aaggaccgca ccttgagtga ctatgcaggt
     9481 aactggcaat cagtttatcc tttccttgaa gacggcacgt ttgaccaagt ctttgactac
     9541 aaggctaagt tgactggtaa gatgacccag gctgagtaca aggcttacta tacaaaaggc
     9601 tatcagacag atgtgactaa gattaacatt actgataata ctatggaatt tgttcaaggt
     9661 ggacaaagca agaaatacac ttacaagtat gtcggtaaga aaattttgac ttacaagaaa
     9721 ggcaatcgtg gcgtgcgttt cctctttgaa gccacagatg ctgacgctgg acaattcaag
     9781 tatgttcagt ttagtgacca caatgttgcc ccagttaagg cagaacattt ccatatcttc
     9841 tttggaggca caagccaaga agccctcttt gaagaaatgg acaactggcc aacctactac
     9901 ccagataacc tatctggcca agaaatcgcc caagaaatgt tggcgcattg atgagaaatc
     9961 gactagttca taagagctag tcggtttttt gatactagat ggctaacttc attatagacc
    10021 tttcagaact ttaaacaata aataaaactc ttgaaatatc tgggcttata tgctagaatg
    10081 tagttagtgt ataaggttca ttagaacacc aaagccccta actagtgcca tagttaaggg
    10141 cttttttgac gtatcttagc gatttaacgg gtgtttatag gctagtcagt cggtctactt
    10201 cttaccatct agccatttgc agacgaaata caagataatt ccagctataa catctgctat
    10261 aatagtaaga gcaagctctg gtataaggct cattagtttc acctcctctc acgaacccat
    10321 aggaacgtaa tcggtaaccg atgacaaaag tattatatca cactaaattt agatcatcaa
    10381 cctcacttaa tgcttgaact attgtagatt atatgctaaa atgtagttaa ttgataaggt
    10441 tcattagaac accaaagccc ctaactatgg ccgtagttaa gggctttttt gacgtatctt
    10501 agcgatttaa cgggtgttta taggctagtc actcggtcta cttcttacta tctagccatc
    10561 tgcagacgaa atacaagata attccagcta taacatccgc tataatagta agagcgagct
    10621 ctat
//
LOCUS       DAVBOG010000065        10492 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.065, whole genome shotgun sequence.
ACCESSION   DAVBOG010000065 DAVBOG010000000
VERSION     DAVBOG010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10492
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.065"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(26..628)
                     /locus_tag="VQ865_001902"
                     /pseudo
     CDS             complement(26..628)
                     /locus_tag="VQ865_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014931989.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
     gene            complement(1214..1990)
                     /locus_tag="VQ865_001903"
     CDS             complement(1214..1990)
                     /locus_tag="VQ865_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000406168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HET3136201.1"
                     /translation="MEISKGIIFNIQHFSIHDGPGIRTTVFLKGCPLRCPWCSNPESQ
                     RMKPEKMKDAQREKFTLVGEEKTVEEIITEVLKDKEFYEESGGGLTLSGGEIFAQFEF
                     AKAILKSAKEHHIHTAIETTAFVDHEKFIDLIQYVDFIYTDLKHYNSIKHKKVTGVFN
                     QMIIKNIHYAFSQNKTIVLRIPVIPNFNNSLEDAEKFATLFNSLNIDQVQLLPFHQFG
                     ENKYRLLNRKYEMDGVNALHPEDLIDYQKVFLNHHINCYF"
     gene            2112..2858
                     /locus_tag="VQ865_001904"
     CDS             2112..2858
                     /locus_tag="VQ865_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HET3136202.1"
                     /translation="MKRLEQIIKLVSEYEKIDVNTLSEKLNVSKVTIRKDLDKLESKG
                     LLHREHGYAVLNSGDDLNVRLSINYEIKRKIVQEAVKLVSDNETIMIESGSTCALLAE
                     EICKQKRNVTIVTNSFFIANFVRAYDSCRIIVLGGEFQKDSQVTVGPLLKEMIQTFHV
                     RQAFVGTDGYDKEMGFTGKDLMRSEVVQYISAASDKVIVLTDSSKFDKRGTVRRFALS
                     QVYEVITDEKLSKQNIATLENAGIMVKVVS"
     gene            2871..3851
                     /locus_tag="VQ865_001905"
     CDS             2871..3851
                     /locus_tag="VQ865_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001070834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HET3136203.1"
                     /translation="MNQDRNKLLSKIAYLYYIENLNQSQIAAKLGIYRTSISRMLTEA
                     RNAGIVKIEIENFDANMFKLENYVKEKYGLESLEIIPNEFDDNPTILSERISQVAAGV
                     LRNLIDDNMKIGFSWGKSLSNLVDLIHSKSVRNVHFYPLAGGPSHIHAKYHVNTLIYE
                     MSRKFHGECTFMNATIVQENKLLADGILQSRYFENLKNSWKDLDIAVVGIGDFSNKGK
                     HQWLDMLTEDDFKELTKVKTVGEICCRFFDSKGKEVYENLQERTIAISLEDLKNIPQS
                     LAVAYGDTKVSSILSVLRANLVNHLITDKNTILKVLEEDGDLTFREILGE"
     gene            4046..4366
                     /locus_tag="VQ865_001906"
     CDS             4046..4366
                     /locus_tag="VQ865_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3136204.1"
                     /translation="MEIIVPDQIIMGLILYAGDAKQHIYKALDYIKNGTCERCEEEIQ
                     LADAALLEAHNLQTKFLAQEASGTKTEITALFVHSQDHLMTSMTEINLIKEIISLRKE
                     LHKK"
     gene            4412..4720
                     /locus_tag="VQ865_001907"
     CDS             4412..4720
                     /locus_tag="VQ865_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000238716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3136205.1"
                     /translation="MVKIGLFCAAGFSTGMLVNNMKIAAQASGVEAEIEAFSQSKLAD
                     YAPNIDVALLGPQVAYTLDKSKEICDKCDVPIAVIPMMDYGMLDGKKVLDLALSLISG
                     "
     gene            4737..6035
                     /locus_tag="VQ865_001908"
     CDS             4737..6035
                     /locus_tag="VQ865_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3136206.1"
                     /translation="MSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLI
                     MGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALP
                     AGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIK
                     RKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQV
                     PLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKAMLASANLS
                     LENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNE
                     PVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFL
                     VGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS"
     gene            6186..8624
                     /locus_tag="VQ865_001909"
     CDS             6186..8624
                     /locus_tag="VQ865_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HET3136207.1"
                     /translation="MVNTEVARTTIKTEYFGSLTERMNKYREDVLNKKPYIDAERAVL
                     ATRAYERYKEQPNVLKRAYMLKEILENMSIYIEEESMIAGNQASSNKDAPIFPEYTLE
                     FVLNELDLFEKRDGDVFYITEETKEQLRSIAPFWENNNLRARAGALLPEEVSVYMETG
                     FFGMEGKMNSGDAHLAVNYQKLLQFGLRGFEERARKAKVALDLTDPASIDKYHFYDSI
                     FIVIDAIKVYAKRFVALAKSLAENANPKRKKELLEIADICSRVPYEPATTFAEAIQSV
                     WFIQCILQIESNGHSLSYGRFDQYMYPYMKADLESGKETEDSIVERLTNLWIKTITIN
                     KVRSQSHTFSSAGSPLYQNVTIGGQTRDKKDAVNPLSYLVLKSVAQTHLPQPNLTVRY
                     HAGLDARFMNECIEVMKLGFGMPAFNNDEIIIPSFIAKGVLEDDAYDYSAIGCVETAV
                     PGKWGYRCTGMSYMNFPKVLLITMNDGIDPASGKRFAPSFGHFKDMKNFSELENAWDK
                     TLRYLTRMSVIVENSIDLSLEREVPDILCSALTDDCIGRGKHLKEGGAVYDYISGLQV
                     GIANLSDSLAAIKKLVFEEERISPSQLWHALETDYAGEEGKVIQEMLIHDAPKYGNDD
                     DYADKLVTAAYDIYVDEIAKYPNTRYGRGPIGGIRYSGTSSISANVGQGRGTLATPDG
                     RNAGTPLAEGCSPSHNMDQHGPTSVLKSVSKLPTDEIVGGVLLNQKVNPQTLAKEEDK
                     LKLIALLRTFFNRLHGYHIQYNVVSRETLIDAQKHPEKHRDLIVRVAGYSAFFNVLSK
                     ATQDDIIGRTEHTL"
     gene            8643..9311
                     /locus_tag="VQ865_001910"
     CDS             8643..9311
                     /locus_tag="VQ865_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000395441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HET3136208.1"
                     /translation="MEFMLDTLNLDEIKKWSEILPLAGVTSNPTIAKREGSINFFERI
                     KDVRELIGSTPSIHVQVISQDFEGILKDAHEIRRQAGDDIFIKVPVTPAGLRAIKVLK
                     KEGYHITATAIYTVIQGLLAIEVGADYLAPYYNRMENLNIDSNSVIRQLALAIDRQNS
                     PSKILAASFKNVAQVNNALAAGAHAVTAGADVFESAFAMPSIQKAVDDFSDDWFVTQN
                     SRSI"
     gene            9329..10417
                     /locus_tag="VQ865_001911"
     CDS             9329..10417
                     /locus_tag="VQ865_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001860765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol dehydrogenase"
                     /protein_id="HET3136209.1"
                     /translation="MRIFASPSRYIQGENALFENAKSILDLGNYPILLCDQLVYDIVG
                     KRFEDYLHRYGFHIVLALFNGEASDNEINRVVALAEKENCDSIIGLGGGKTIDSAKAI
                     ADLIEKPVIIAPTIASTDAPVSALSVIYTDEGAFDHYLFYSKNPDLVLVDTKVISQAP
                     KRLLASGIADGLATWVEARAVMQANGKTMLGQQQTLAGVAIAKKCEETLFADGLQAMA
                     ACEAKVVTPALENIVEANTLLSGLGFESGGLAAAHAIHNGFTALTGDIHHLTHGEKVA
                     YGTLVQLLLENRPKEELDKYIEFYKKIGMPTTLKEMHLDQVGYDDLIKVGKQATMEGE
                     TIHQMPFKISPSDVAQAIIAVDAYVNSK"
BASE COUNT         3436 a         1487 c         2088 g         3481 t
ORIGIN      
        1 aatttgtcct gttcttattt cattttacta taccatcaat aagtgtgaaa agatctttta
       61 cataagacca agccttatta tctttgtaac caccttgagc ttgtagcata tttgttaatt
      121 gagcaaaggc gctagaagag tttgctgggt cagcagttgc gatttttcct tttagttcag
      181 gtttgagaag gtcgctatat ccttcgatgt tcatgccttt agttaaatca gggtggacga
      241 ttaaaacact accatctagt gtataaggag tagagaagcc agttgtgttt tgatattctt
      301 tgataacatt atcattttct tttgaaatat agttttcaaa gagttctccg tgggtagcat
      361 attgtgtata agaaccacca aagataacat cagctacagg aacttctttt tctgactcta
      421 gttttttgaa aagttctcca gtaccagctt gaatcagttc tattttgata ccatattttt
      481 cttcaaaggc aggaatagtt gctccaatta agccttctga gtttggtgaa taaacgacta
      541 gcgaaccacc gtctccttta tcagatgaac tgtcatcggc agattcatta gaagaacaag
      601 cagcataata catccatttc tttttcatga tggatacctc cgttgtgtta tttaagttta
      661 ttttaaaaca atgtaagcgt ttttaaaacc tacaattcta ttctatagtg tattgaatct
      721 ataacagtac accttgactg ctaaaatatt tctataaatt aatttgactt tcctgataga
      781 gatgttcaca tcttatttca attcactata ttagagtaaa attctctaca aaaaaaagaa
      841 tagcctattt tactattttt ccgagtgatt tcaattcctt tggggaaata tggagatact
      901 ttttaaatcc tgacaaatgg ttgtttcttt ttctaaatcg gtgatactgt atcggagaat
      961 gcgcgtgagg tcacaaaggc tgcgatagag cttctatgga gaatttcttt ttggagagat
     1021 tttttaaagg aatgagacat ccgctacctc cttggaaggt tttttgtgat aagtatagca
     1081 gtttaaaaat tctagagcaa ggtaaaatag aaaaggtttg gctaaaattt tttagctaaa
     1141 ccttttgaaa agttaagtat gtattataga tgcttgttat ctgcaaatat ctagagcatt
     1201 tcaaggaaat aaactagaaa taacaattaa tatggtggtt cagaaatacc ttttgataat
     1261 caataagatc ttcaggatga agtgcgttga ctccatccat ttcatatttc cgatttaata
     1321 aacgatattt gttttcacca aattgatgaa aagggagtag ttgaacttgg tcgatattta
     1381 atgagttaaa tagagtagcg aatttttctg catcctctaa actattgtta aaattaggaa
     1441 taactgggat tcttaaaacg atagttttat tttgagaaaa agcataatga atgtttttaa
     1501 taatcatttg attaaaaacc ccagtcactt ttttatgttt tatagaatta taatgtttta
     1561 ggtctgtgta gataaaatcc acatattgaa ttaaatcgat aaatttttca tgatcaacaa
     1621 aggcagtagt ttcaatggca gtgtgtatgt gatgttcttt agctgatttt aagatggctt
     1681 tagcaaattc aaactgagca aatatttcac ctcctgataa agttaaacct ccaccggatt
     1741 cttcgtaaaa ttctttgtct tttaatacct ctgtaataat ttcttctaca gtcttttctt
     1801 caccgactaa ggtgaatttc tctcgttgag catctttcat tttttcaggt ttcattcttt
     1861 gagattcagg attagaacac catggacagc gcagaggaca tccttttaaa aaaacagttg
     1921 tacgaatacc cgggccgtca tgaattgaaa agtgttgaat attaaaaata attcctttag
     1981 atatttccat aagagttcct cctcttcata agtctatcct atcacaaaaa cgaaagaaaa
     2041 acaattacga acgaaaggtt aatttgttgt tttttgcttt ttattttggt agaataaaac
     2101 ggaggtgtaa aatgaaaaga ttggaacaaa ttattaaatt agtatcagaa tatgaaaaga
     2161 tcgacgttaa tacattatcg gaaaaattaa atgtatcgaa agtaacgatt agaaaagatt
     2221 tagataaatt agagtcaaaa ggtttattac acagagagca tggatatgct gtattaaata
     2281 gtggagatga cttaaatgta cgtttgtcaa ttaattatga aattaagaga aaaattgttc
     2341 aggaagcagt aaaattggtg tcagataatg aaacaataat gatagaatct ggatcgacct
     2401 gtgctttact tgctgaggaa atttgcaagc aaaaaagaaa tgttacgatt gtaacaaatt
     2461 cattttttat agcaaatttt gtgagagctt atgattcatg tcgtattatt gttcttggtg
     2521 gagagtttca gaaggattca caggttactg tgggaccttt attaaaagaa atgatacaga
     2581 cttttcatgt gcgtcaagct tttgttggga cagatggcta cgataaagag atgggcttta
     2641 caggaaaaga tttaatgcgc agtgaggtag ttcaatatat ttcagcagcg tcggataaag
     2701 tcattgtact aactgactca agtaaatttg ataaaagggg tacagtaaga agatttgctt
     2761 taagtcaagt ctatgaagta ataacagacg aaaaactttc taaacaaaat atagctacat
     2821 tagaaaatgc tgggataatg gttaaggtag tttcgtaaga ggttaagtgt atgaatcaag
     2881 ataggaataa actgctctct aaaattgctt atctgtatta tattgaaaac ttaaatcagt
     2941 cacaaatagc agcaaaatta ggaatttata gaacctctat tagtagaatg ttaacagaag
     3001 caaggaatgc aggaattgtt aaaattgaaa tagagaattt tgatgccaat atgtttaagt
     3061 tggaaaatta tgtaaaagaa aaatatggtc tggaaagttt agaaattatt ccaaatgaat
     3121 ttgatgataa tccaacaatt ttatctgaaa gaatttctca agttgcagca ggtgtcctta
     3181 ggaatctaat tgatgataat atgaaaattg gcttttcttg ggggaaaagt ttaagtaatt
     3241 tagtagattt aattcacagt aaaagtgtcc gaaatgttca cttctatcct ctagcaggtg
     3301 gtcctagtca catacacgct aaataccatg tgaatacact gatttatgaa atgtctagaa
     3361 aatttcatgg agagtgtaca tttatgaatg caacgattgt gcaagaaaat aaattgttag
     3421 cagatggtat tttgcaatca agatattttg aaaatttgaa aaatagttgg aaagatttag
     3481 atatagctgt agtcggaatt ggtgatttta gcaataaagg aaagcatcaa tggttagaca
     3541 tgcttacaga ggatgacttt aaagaattga ccaaagttaa aactgtagga gaaatttgtt
     3601 gtcgattttt tgattcaaaa ggtaaagaag tctatgaaaa cttacaggaa agaacgatag
     3661 caatctcttt ggaagattta aaaaatattc ctcaaagttt agctgttgct tacggtgata
     3721 cgaaagtatc ttcgattctt tctgtcttgc gtgctaattt agtaaatcat ttgattacag
     3781 acaaaaatac aattttaaaa gttttggaag aagatgggga tttgactttt agagagattc
     3841 taggtgagtg aaaatgatag actgattcag tttatcgttt ttctttttag ttgattgcac
     3901 atttgtgctt atataaacaa aaatagttta tctgttgttt ttggattgac aactttatta
     3961 tgtagttgta ttctatagtt acaaaagaaa attttaaaat ttcaaatgaa aaaagctttt
     4021 tacatagtga aatgaggagg aatttatgga aattattgtt ccagatcaaa ttatcatggg
     4081 tttaatttta tatgctggcg atgcgaaaca acatatttat aaagcattag attacataaa
     4141 gaacggtaca tgtgaacgat gtgaagaaga aatccagtta gctgatgccg ccttattaga
     4201 agctcataat ctacaaacaa aattcttggc acaggaagcg tctggtacaa agacagaaat
     4261 tacagctctc tttgttcatt cacaagatca tctcatgact agtatgacgg agattaattt
     4321 aatcaaagaa attattagtt tgagaaaaga acttcataaa aaataatact agagtattat
     4381 cattgttatt aacatagagg aggaaaacat aatggtgaag attggtttgt tttgtgcagc
     4441 aggtttttct actggtatgc ttgtaaataa tatgaaaatt gcagcgcaag ctagtggagt
     4501 tgaggcagaa atagaggcgt tttctcagtc taaattagcg gattatgcgc caaatataga
     4561 tgttgcacta ttgggtccac aagttgctta tacattagat aaatcaaaag aaatttgtga
     4621 taagtgtgat gttccgatag ctgttattcc gatgatggac tatggtatgt tagatgggaa
     4681 aaaagtatta gatttggccc tatctttgat tagtgggtaa gaaaaggaga tttattatgt
     4741 caaagatgga tgttcagaaa atcattgcac cgatgatgaa gtttgtgaat atgcgtggca
     4801 ttatagctct aaaagatggg atgttagcaa ttttgccatt gacagtagtt ggtagtttgt
     4861 tcttgattat gggacaattg ccgttcgaag gattaaataa gagcattgct agtgtttttg
     4921 gagctaattg gacagagccg tttatgcaag tatattcagg aacttttgct attatgggtc
     4981 taatttcttg tttttcaatt gcctattctt atgctaagaa tagcggagta gaggctttac
     5041 cagctggagt tctatctgta tctgcattct ttattttgct aagatcatct tatatcccta
     5101 aacaaggtga ggcgattggg gacgctatta gtaaagtttg gtttggaggc caaggaatta
     5161 tcggtgctat cattataggt ttggtagtag gaagtattta taccttcttt ataaagagaa
     5221 aaattgttat taagatgcca gaacaagttc cacaagctat tgccaaacag tttgaagcaa
     5281 tgattccagc atttgtaatt ttcttatctt ctatgattgt atatatttta gcgaagtcat
     5341 tgactaatgg cggaacattc atagaaatga tttattctgc tattcaagtt ccgttgcaag
     5401 gtttaactgg atctttgtat ggtgctattg gaattgcatt ctttatatca tttttgtggt
     5461 ggtttggtgt tcatgggcaa tcggtagtaa atggagtagt gacagctctg cttttatcta
     5521 atcttgacgc taataaagct atgttagcct ctgctaatct atcattagaa aatggtgcac
     5581 atattgttac tcaacaattt ttagattcat ttttaattct atcaggttca gggattacgt
     5641 ttggtcttgt agttgccatg ctttttgcag caaaatcaaa acaataccaa gccttaggaa
     5701 aagttgcagc ttttccagca atatttaacg taaatgagcc agttgtattt ggatttccga
     5761 ttgtcatgaa tccagttatg tttgtacctt tcattcttgt tcctgtactt gcagctgtga
     5821 tagtatatgg agctattgca acaggtttca tgcagccatt ctcaggggta acattgcctt
     5881 ggagtacacc agctattcta tcaggatttt tggtgggtgg atggcaaggt gttgtgactc
     5941 agttattagt attggtgata tctacagtgg tttactttcc attctttaag atacaagatc
     6001 gtttagctta ccaaaatgaa atcaaacaat cttagaggta tttgtgtgtt actgttaaac
     6061 tcacacattt gtgctaaaaa ttagagagtt aaaatttttc tagttaaaag cttgaaaatt
     6121 tctataaaaa tcggtattat attttcgaaa gaaataaaaa tattttcgaa agaaaggtgc
     6181 ttacgatggt aaatacagaa gtagcaagaa caacaatcaa gacagaatat tttggcagcc
     6241 ttactgaaag gatgaacaaa tatcgagaag atgttttaaa taaaaaacct tatattgatg
     6301 ctgagagagc agttctagca acacgcgcct atgaacgata caaggaacaa cctaatgtcc
     6361 taaaacgtgc atatatgctg aaagaaattt tggaaaatat gtctatctat attgaagaag
     6421 aatctatgat tgcgggaaat caagcttctt ccaataaaga tgctcctatt tttccggaat
     6481 atacgctaga atttgttctc aatgagttgg atctttttga aaagcgtgat ggagatgttt
     6541 tctatattac agaagaaaca aaagaacaac ttagaagtat tgctccgttt tgggaaaata
     6601 ataatttacg tgctagagct ggtgccttat tacctgaaga agtgtcagtt tatatggaaa
     6661 caggattctt cggtatggaa ggtaagatga attctggaga tgctcactta gcagttaact
     6721 atcagaaact tttgcaattt ggtttaagag gttttgaaga gcgggctcgt aaagcaaaag
     6781 tagctctaga tttaacagat ccagcaagta ttgataaata tcatttttac gactctatat
     6841 ttattgtaat cgatgctatt aaagtatatg caaagcgctt tgttgctctt gctaaaagtt
     6901 tagccgaaaa tgcaaatcct aaacgtaaga aagaattact tgagattgca gatatttgct
     6961 ctagagtccc atatgaaccg gcaactactt ttgcagaagc tattcaatca gtttggttta
     7021 ttcaatgtat tttacaaatt gaatctaatg gccactctct ttcatatggc cgttttgatc
     7081 aatatatgta tccatatatg aaggctgatt tagaaagtgg taaagaaaca gaagatagca
     7141 ttgttgaacg tctgacaaat ctttggatta agacaattac aattaataag gttcgcagtc
     7201 aatcacatac attttcttca gcaggaagtc ctttatatca aaatgttaca attggtggac
     7261 agactcgaga taagaaggat gctgttaacc cattatctta tttggtatta aaatcagttg
     7321 cacaaaccca tctaccgcaa cctaatctaa ctgtacgtta ccatgcaggt ttagatgctc
     7381 gtttcatgaa tgagtgtatt gaagtgatga aacttggttt tggtatgcct gcatttaata
     7441 atgatgagat tattattcct tcttttattg caaaaggagt attggaagat gatgcttatg
     7501 attacagtgc cattggatgt gttgaaacgg cagttccagg gaaatggggc tatcgttgca
     7561 caggtatgag ttatatgaac ttccctaagg ttctacttat cacgatgaat gatggaattg
     7621 atccggcttc gggtaaacgg tttgcaccaa gctttggtca ttttaaggat atgaagaact
     7681 tttctgaatt agaaaatgct tgggataaaa cactaagata tttgacacga atgagtgtta
     7741 ttgttgaaaa ttctattgat ttatcattgg aacgagaagt tcctgatatt ctatgttcag
     7801 cattgactga tgattgtatt ggtcgtggaa aacaccttaa agaaggtgga gcagtatatg
     7861 attatatatc aggattgcaa gttggaattg caaatttgtc ggattcatta gctgcaatta
     7921 aaaaattggt gtttgaggaa gaacgtataa gcccaagtca gctttggcat gcactggaaa
     7981 cagattatgc cggagaagaa ggtaaggtca ttcaagaaat gttgattcat gatgcaccta
     8041 agtatggtaa tgatgatgat tatgctgaca aattggttac tgctgcttat gacatttatg
     8101 ttgatgaaat tgctaaatat cctaatacac gttatggaag agggcctatt ggaggaattc
     8161 gttattcagg aacatcttct atatcagcca acgtagggca gggacgtgga acattagcaa
     8221 ctccagatgg acgcaacgcg ggtacaccgt tagcagaggg ttgttcacca tcacataata
     8281 tggatcaaca cggccctaca tctgttttaa aatctgtttc aaaattacca acagatgaaa
     8341 tcgtaggtgg ggttctctta aatcagaaag taaatcctca aacgttagcc aaagaagaag
     8401 ataaattaaa actaattgct ttgttacgaa cattctttaa tcgtttacat gggtaccata
     8461 ttcaatacaa tgttgtttcc agagagacgt tgattgacgc tcagaaacat cctgaaaaac
     8521 acagagactt aattgttcgt gttgcaggat actctgcatt cttcaatgtt ctttctaagg
     8581 caacccaaga tgacattata ggacgtactg agcatacttt gtaaaataaa gaggttcttt
     8641 ttatggaatt tatgcttgac acattaaatt tagatgagat taaaaagtgg tctgaaattt
     8701 tgccgctagc tggggtaact tcaaatccca ctattgcaaa aagagagggt tctattaatt
     8761 tttttgaacg aatcaaagat gtaagagaat tgattggctc cacaccctct attcatgttc
     8821 aggtgatttc tcaagatttt gaaggcatct taaaggatgc tcatgaaatt cgaagacaag
     8881 caggagatga tatatttatc aaagtacctg ttactccagc tggattacgt gcaataaagg
     8941 tgctaaaaaa agagggctac catatcactg caacagctat ttatacagtt attcagggat
     9001 tattagctat cgaagtagga gcggattacc tagctccata ttataataga atggaaaatc
     9061 tgaacattga ttcaaattct gtcattcgtc aattagctct tgctattgat agacagaact
     9121 ctcctagtaa gattttagct gcatccttta aaaatgtagc acaagtaaat aatgctttag
     9181 ctgcaggtgc gcatgctgtt acagcaggag cagatgtttt tgaatcagct ttcgccatgc
     9241 catctatcca aaaggcggtt gatgattttt ctgacgattg gtttgttact caaaatagtc
     9301 gttccattta gatagagagg aaatacatat gagaattttt gctagtcctt ctagatatat
     9361 tcagggggaa aatgccttgt ttgaaaatgc caaatcaatt ttggatttgg gaaattaccc
     9421 gattctatta tgcgatcagt tggtttatga tattgttgga aaacgatttg aagattatct
     9481 acataggtat ggtttccata ttgttctggc gctatttaat ggtgaagctt ctgacaatga
     9541 aatcaatcga gttgttgcct tggctgagaa agaaaattgt gatagtatta tcggtcttgg
     9601 tgggggaaag acgattgata gcgcaaaagc tattgcagat ttgattgaaa agcctgttat
     9661 tattgctcca acaattgcat cgaccgacgc acctgtatct gctttatctg ttatttatac
     9721 agatgaaggt gcatttgatc attatctatt ttattctaaa aatccagatt tagttttggt
     9781 tgatacaaaa gttatttcac aagcccctaa gcgtttatta gcgtctggta ttgcagatgg
     9841 tttagcaact tgggttgagg cgcgtgcggt tatgcaggca aatggaaaaa ctatgttggg
     9901 acaacagcaa acattggctg gagttgcaat tgcgaagaaa tgtgaagaaa cgctgtttgc
     9961 agatggttta caggctatgg cagcttgtga agctaaagtg gtgacaccag cattagaaaa
    10021 tattgttgaa gctaatactt tattgagtgg tctaggtttt gaaagtggag gattagctgc
    10081 ggcgcatgca attcataatg gttttactgc attgacaggt gacattcatc atttaacaca
    10141 tggtgaaaaa gtagcttatg gaactttagt acaactatta ttggaaaata gacctaaaga
    10201 agaacttgat aagtatattg agttttacaa aaaaattggt atgccaacaa ctctaaaaga
    10261 aatgcatttg gatcaagttg gatatgatga tttaataaaa gttggtaaac aagcaactat
    10321 ggagggtgag acaattcatc agatgccgtt taagatttcg ccctcagatg ttgctcaagc
    10381 tattatcgct gtagatgcct atgtaaattc aaaataaaca ataaggacta ctgttttcca
    10441 aatggtagtc ttttattgat ccctgtattg aattctatag cagattgaaa ta
//
LOCUS       DAVBOG010000066        10489 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.066, whole genome shotgun sequence.
ACCESSION   DAVBOG010000066 DAVBOG010000000
VERSION     DAVBOG010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10489
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.066"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            154..366
                     /locus_tag="VQ865_001912"
                     /pseudo
     CDS             154..366
                     /locus_tag="VQ865_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            266..712
                     /locus_tag="VQ865_001913"
     CDS             266..712
                     /locus_tag="VQ865_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3136210.1"
                     /translation="MRKHGLISKSTSKGYYQVAIPFMRLFCLVLVSIDYINCLSETTD
                     KNWHKSDRIFVTNTGKPVHSSILSKSLQRANERLKKPIPKHLSPHIFRHTTISILSEN
                     KIPLKTITDRVGHSDSEVTTSIYTHVTKNMKDEAINVLDKVMKKIF"
     gene            complement(850..2154)
                     /gene="eno"
                     /locus_tag="VQ865_001914"
     CDS             complement(850..2154)
                     /gene="eno"
                     /locus_tag="VQ865_001914"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002985288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HET3136211.1"
                     /translation="MSIITDVYAREVLDSRGNPTLEVEVYTESGAFGRGMVPSGASTG
                     EHEAVELRDGDKSRYGGLGTQKAVDNVNNIIAEAIIGYDVRDQQAIDRAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEIPLYSYLGGFNTKVLPTPMMNIINGGSHSDAPI
                     AFQEFMILPVGAPTFKEALRYGAEIFHALKKILKSRGLETAVGDEGGFAPRFEGTEDG
                     VETILAAIEAAGYVPGKDVFIGFDCASSEFYDKERKVYDYTKFEGEGAAVRTSAEQID
                     YLEELVNKYPIITIEDGMDENDWDGWKALTERLGKKVQLVGDDFFVTNTDYLARGIQE
                     GAANSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTIADIAVATNAGQ
                     IKTGSLSRTDRIAKYNQLLRIEDQLGEVAEYRGLKSFYNLKK"
     gene            2318..2764
                     /locus_tag="VQ865_001915"
     CDS             2318..2764
                     /locus_tag="VQ865_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000131081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HET3136212.1"
                     /translation="MTDLSKQLLEKAHGGLKINPDEQRRYLGTFEERVLGYVDIDTAN
                     SPQLEKGFLFILENLQEKAEPLFVKISPTIEFDKQVFYLKEAKETDSQATIVSEEHIT
                     SPLGLVIHSNAPVQVEEKDLRLAFPKLWEVKKEEPAKTSLWKKWFS"
     gene            complement(2761..3876)
                     /locus_tag="VQ865_001916"
     CDS             complement(2761..3876)
                     /locus_tag="VQ865_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000706318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HET3136213.1"
                     /translation="MKIVIAPDSFKESLTAQQVAEAIKRGFQQSIADVECLLCPVGDG
                     GEGTVDAIRHSLDLKEKWIQVTDPSGQKEAMRYFQKGELALFEVADLVGLGKIPLEKR
                     NPLQIQTCGIGELILHLISKGIKDIYIGVGGTASNDGGLGIAAGLGYQFYDRDGNVLP
                     ASDQSLLNLASVSTENCYKIPEGVQIHILADVVSPLCGHQGATYTFGNQKGLHPTMFA
                     VVDQAIQDFYEKFSPATLEIKGAGAGGGLAGGLCAFAQASIVSGIDTCLDLINFDKKV
                     SDADLVVVGEGRLDSQSFAGKAPIGVAKRTPVGVPVIAICGSLAEDLPPLPFENIQAV
                     FSILEKSEPLEDSLKNASLYLERTAANIGHLLNMCKI"
     gene            complement(3990..4214)
                     /locus_tag="VQ865_001917"
     CDS             complement(3990..4214)
                     /locus_tag="VQ865_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HET3136214.1"
                     /translation="MERLAKSLGIAYFTANQLEVKEGLLTGKLVGQIISPQVKKETLE
                     KWRKKLKLSKERTVAIGDGVNNLLMLKSAE"
     gene            complement(4159..4530)
                     /locus_tag="VQ865_001918"
     CDS             complement(4159..4530)
                     /locus_tag="VQ865_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IB family phosphatase"
                     /protein_id="HET3136215.1"
                     /translation="MSQVKGLCVLDVDGTLILEEVIDLLGREAGHEAEISQITSRAMR
                     GELVFESSLRKRVSLLEGLPILVFDNVFNSIHLSLNVPEFISILQKNGILVGLVSGGF
                     TPIVGEISKIPWYCLFHCQPA"
     gene            complement(4589..6022)
                     /gene="glgA"
                     /locus_tag="VQ865_001919"
     CDS             complement(4589..6022)
                     /gene="glgA"
                     /locus_tag="VQ865_001919"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000697278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HET3136216.1"
                     /translation="MKILFVAAEGAPFSKTGGLGDVIGALPKSLVKAGHEVAVILPYY
                     DMVEAKFGSQIEDVLHFEVSVGWRRQYCGIKKTVLNGVTFYFIDNQYYFFRGHVYGDF
                     DDGERFAFFQLAAIEAMERIDFIPDLLHVHDYHTAMIPFLLKEKYRWIQAYEDIETVL
                     TIHNLEFQGQFSEGMLGDLFGVGFERYADGTLRWNNCLNWMKAGILYANRVSTVSPSY
                     AHEIMTSQFGCNLDQILKMESGKVSGIVNGIDADLYNPQTDALLDYHFNQEDLSGKAK
                     NKAKLQERVGLPVRADVPLVGIVSRLTRQKGFDVVVESLHHILQEDVQIVLLGTGDPA
                     FEGAFSWFAQIYPDKLSTNITFDVKLAQEIYAACDLFLMPSRFEPCGLSQMMAMRYGT
                     LPLVHEVGGLRDTVRAFNPIEGSGTGFSFDNLSPYWLNWTFQTALDLYRNHPDIWRNL
                     QKQAMESDFSWDTACKSYLDLYHSLVN"
     gene            complement(6019..7158)
                     /gene="glgD"
                     /locus_tag="VQ865_001920"
     CDS             complement(6019..7158)
                     /gene="glgD"
                     /locus_tag="VQ865_001920"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase subunit
                     GlgD"
                     /protein_id="HET3136217.1"
                     /translation="MKIDKYSAILGNTVGFHNMSTLTDHRPVASLPFGGKYRLIDFPL
                     SSLANAGVRSVFGIFQQDNISSVFDHIRSGREWGLSTLLSHYYLGIYNTRVESSTVGK
                     EYYQQLLTYLKRSGSNQTVALNCDVLINIDLNQVFHLHSTTKEPITVVYKKLAKKDIS
                     EVNAILDVDETDHVLSHKLFDSKSTAETFNMSTDIFVVDTPWLIEHLEEEAKKEHPEK
                     LRYVLRDLAVKEGAFAYEYTGYLANIHSVKSYYQANIDMLESQKFYSLFSPNQKIYTK
                     VKNEEPTYYANTSKVSTSQFASGSIIEGQVANSVLSRNIHVHKDSLVKDSLLFPRVVI
                     GEGAQVEYAILDKGVEVEPGVVIRGTAEHPVVVKKGAKVTEDIHS"
     gene            complement(7148..8290)
                     /locus_tag="VQ865_001921"
     CDS             complement(7148..8290)
                     /locus_tag="VQ865_001921"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HET3136218.1"
                     /translation="MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALS
                     NCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGT
                     SHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEA
                     SRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDF
                     GKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYS
                     RNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAI
                     IGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED"
     gene            complement(8280..10208)
                     /gene="glgB"
                     /locus_tag="VQ865_001922"
     CDS             complement(8280..10208)
                     /gene="glgB"
                     /locus_tag="VQ865_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching protein GlgB"
                     /protein_id="HET3136219.1"
                     /translation="MDNREALKTFMTGENFYLQHYLGAHREELNGEHGYTFRVWAPNA
                     QAVHLVGDFTNWIENQIPMVRNDFGVWEVFTNMAQEGHIYKYHVTRQNGHQLMKIDPF
                     AVRYEARPGTGAILTELPEKKWKDGLWLARRKRWGFEERPVNIYEVHAGSWKRNSDGS
                     PYSFAQLKDELIPYLVEMNYTHIEFMPLMSHPLGLSWGYQLMGYFALEHAYGRPEEFQ
                     DFVEECHTHNIGVIVDWVPGHFTINDDALAYYDGTPTFEYQDHNKAHNHGWGALNFDL
                     GKNEVQSFLISCIKHWIDVYHLDGIRVDAVSNMLYLDYDNAPWTPNKDGGNLNYEGYY
                     FLQRLNEVIKLEYPDVMMIAEESSSATKITGMKEIGSLGFDYKWNMGWMNDILRFYEE
                     DPIYRKYDFNLVTFSFMYVFKENYLLPFSHDEVVHGKKSMMHKMWGDRYNQFAGLRNL
                     YTYQICHPGKKLLFMGSEYGQFLEWKSEEQLEWSNLEDPMNAKMKYFASQLNQFYKDH
                     RCLWEIDTSYDGIEIIDADNRDQSVLSFIRKGKKGEMLVCIFNMVPVERKDFTIGLPV
                     AGIYEEVWNTELEEWGGVWKEHNQTVQTQEGLWKDYEQTLTFTLPAMGASVWKIKRRL
                     KSTKTVTNKNQKGVENEK"
BASE COUNT         3194 a         2299 c         1845 g         3151 t
ORIGIN      
        1 cttggtttca gaaatttctc ttaccaacat taaccgcacc attggttatt atattaaaac
       61 gaagtaagaa taggacaaat cgatcaggac agtaaaatct aattctaaca atgttttaga
      121 agtagaggtg tactattcta gtttcaatct actatattaa tggacaatgc aagattccat
      181 agaatgggga agctagaact cttgtgtgaa gagtttgggc ataaactttt acctcttcct
      241 ccctactcgc ctgagtacaa tcttattgag aaaacatggg ctcatatcaa aaagcacctc
      301 aaaagggtat taccaagttg caataccttt tatgaggctc ttttgtcttg ttcttgtttc
      361 aattgactat ataaattgtc taagcgaaac aaccgataag aattggcaca aaagcgaccg
      421 tatttttgtt accaatacag gaaaaccagt tcatagttct atcttgagca agtctctcca
      481 gcgagcaaac gaacgcctta aaaaaccaat tcccaaacat ctgtcccctc acatcttcag
      541 acacaccact attagcatct tatcagaaaa taaaattcct ttaaaaacaa tcacggacag
      601 ggttggtcat tccgactctg aagtcactac ttccatctac acccacgtca caaagaacat
      661 gaaagatgaa gcaatcaatg tactggataa agttatgaaa aagatttttt aaaaagtttt
      721 gtcccttttt tgtcctctaa atacaaaaat agcccttcgg ataaaatccg aggggctaga
      781 aacgttgtta aatcaacggc cgaacttttg aatttcatgg ttcgggataa aatagttcac
      841 tgaactattt tattttttaa ggttgtagaa tgatttcaat ccacgatatt cagctacttc
      901 accaagttgg tcttcgatac gaagcaattg gttgtattta gcgatgcggt ctgtacgtga
      961 aagtgaacca gtcttgattt gtcctgcgtt agttgcaact gcaatatcag cgattgttga
     1021 atcttcagtt tcacctgaac ggtgtgatac aacagcagtg taaccagctt ctttagccat
     1081 ttcgatagct tcaaaagttt cagtaagagt accgatttgg ttaactttga taaggattga
     1141 gttagcagca ccttcttgga taccacgtgc aaggtagtca gtgtttgtta cgaagaagtc
     1201 gtcaccaaca agttgtactt tcttaccaag acgttcagta agagctttcc aaccatccca
     1261 gtcgttttca tccataccat cttcaatagt gatgattggg tatttgttaa ccaattcttc
     1321 aaggtagtcg atttgttctg cagatgtacg aacagcagca ccttcacctt caaatttagt
     1381 gtagtcgtaa actttacgtt ctttatcgta gaattctgat gaagcacagt caaatccgat
     1441 aaatacgtct ttacctggta catatccagc agcttcaatc gcagcaagga tagtttcaac
     1501 accatcttca gttccttcga aacgaggagc gaatccacct tcgtcaccta cggcagtttc
     1561 caaaccacgt gatttaagga ttttcttaag agcgtggaag atttcagcac cgtaacgaag
     1621 ggcttcttta aatgttggcg caccaactgg caagatcatg aactcttgga aagcgattgg
     1681 agcgtcagag tgagaaccac cgttgatgat gttcatcatt ggagttggaa gaactttagt
     1741 gttgaatcca ccaaggtagc tgtaaagtgg gatttcaagg tagtcagcag cagcacgagc
     1801 tacagcgata gacacaccga ggattgcatt cgcacccaat ttacctttgt taggagtacc
     1861 gtcaagtgcg atcatagcac ggtcaatagc ttgttgatca cgtacatcgt agccaatgat
     1921 agcttcagca atgatgttgt ttacgttgtc aacagctttt tgtgtaccaa gaccaccgta
     1981 acgagatttg tcaccgtcgc gaagttcaac tgcttcgtgt tcaccagtag aagctcctga
     2041 tggaaccata ccacgtccga aagcacctga ttcagtgtaa acttctactt caagtgttgg
     2101 gttaccgcgt gagtctagga cttcgcgagc gtaaacatca gtaataattg acatttttta
     2161 ctctccttat gagttaaatt ttttacacct ctataatacc ttaaaacccc tcctttttca
     2221 agaaaaaacg ttatctttgt gcaacttttc cttaacttta taaagtaatc gctttctttt
     2281 gtctgtttta ttctaacttt tatgatatac tgttttcatg acagatttat caaaacaatt
     2341 acttgaaaaa gctcatggtg ggttaaaaat aaatccggat gagcaaagac gctatcttgg
     2401 tacttttgag gaaagagttc ttggatatgt agatattgac acagcaaata gccctcagtt
     2461 agaaaaaggc tttttattta ttttagaaaa ccttcaggaa aaagcagagc cactatttgt
     2521 gaagatttca ccaactatcg aatttgataa gcaagttttc tacttaaaag aagcaaaaga
     2581 aactgatagt caagccacca tagtatctga agagcatatt acttctcctt tgggcctggt
     2641 tattcatagc aatgcaccag ttcaagtaga agaaaaagac cttcgacttg cttttccaaa
     2701 actttgggaa gttaaaaagg aagaaccagc caaaacatcc ttatggaaga aatggtttag
     2761 ctaaatcttg cacatattta ataagtgccc aatattggca gccgtgcgct ccagatagag
     2821 actggcattt ttcaaactat cttctaaagg ttcacttttc tccaaaatag aaaagacagc
     2881 ttggatattt tcaaatggta ggggaggtaa atcttcagca agactaccgc aaatagcaat
     2941 aacaggaact ccaacagggg ttctttttgc aacacctata ggcgctttcc cagcaaagct
     3001 ttgactatca agtcttcctt ctccaacaac aaccaagtca gcatctgaaa ctttcttatc
     3061 aaagttgatt aagtccaagc aggtatcaat tccagacacg atacttgcct gagcaaaggc
     3121 acacaaacca ccagcaaggc ctccacctgc tcctgctcct ttaatttcta atgttgcagg
     3181 tgagaatttt tcataaaaat cttggatcgc ctgatctacg actgcaaaca tagtcggatg
     3241 tagacctttt tgattgccaa aagtgtaagt cgcaccttga tgaccacata agggactcac
     3301 gacatctgct agaatatgaa tttgaacacc ttcaggaatt ttatagcaat tttctgttga
     3361 aacagaagct aagtttaata aggattgatc ggaagcaggc aagacatttc catccctatc
     3421 ataaaattga taacctaaac cagcagcaat ccccagtcct ccatcattac tggccgtgcc
     3481 accaacaccg atataaatat ctttaatccc tttagaaatg agatggagaa tcaactctcc
     3541 aataccacaa gtttggattt gaagtggatt tcgtttctct agcggaattt ttccaagacc
     3601 aaccaagtca gctacttcaa atagtgccag ttcccctttt tgaaaatagc gcatggcttc
     3661 tttttgtcca gaagggtctg tcacttggat ccatttttct tttaggtcaa gagaatgtcg
     3721 gatagcatct acagtacctt ctcccccatc accaacaggg cagaggagac attctacatc
     3781 tgctatcgat tgttggaagc ctctttttat tgcttcagct acctgttgag ctgtcaagct
     3841 ttccttaaac gaatccggtg caattacaat cttcatattt tccctcattc taaacagtca
     3901 atcaaaggaa gaacttctaa aaaatccctc ttgtcaacat gatgtggtat ttcttttttg
     3961 agcatttctt tggaacaaaa ggcgattcct cactccgccg acttcaacat taatagatta
     4021 ttgaccccat caccgattgc caccgttctt tctttagaaa gttttagttt ctttctccat
     4081 ttttccagag tttctttttt gacctgggga cttataattt gtccaactaa ttttcctgtt
     4141 aaaagacctt ctttgacttc aagctggttg gcagtgaaat aggcaatacc aagggatttt
     4201 gctaatctct ccaactattg gtgtaaatcc accagacacc agaccaacta ggatgccatt
     4261 cttttggaga atagagatga actctgggac atttagcgat agatgaattg agttgaagac
     4321 gttatcaaag accaaaatag gaagaccttc caacaaggac actctttttc ttaaactgct
     4381 ttcaaagacc aactctcctc gcattgctcg acttgtaatc tgcgaaattt ccgcctcatg
     4441 acctgcctct ctccctaaaa gatcaatcac ttcttctagg attaaggttc catctacatc
     4501 caaaacacac aagcctttta cttgagacat cagttctcct ctctaaacag cctaaaaatc
     4561 gtatgaagtc atcatacgat tttatctatt aattaactaa actatggtac aagtcaaggt
     4621 atgacttgca ggctgtatcc catgagaagt cactctccat agcttgtttt tgtaggtttc
     4681 tccaaatgtc tggatggttt ctatacaagt ccaatgctgt ttggaaagtc caatttaacc
     4741 aataaggaga tagattgtca aagctaaagc cagtaccgct tccttcgatt ggattgaaag
     4801 cgcgaactgt atctcgcaag cctccaactt catggaccaa tggcaaggtt ccataacgca
     4861 tagccatcat ttgagacaag ccacacggtt caaaacgact tggcatgagg aagaggtcac
     4921 aagcagcgta gatttcctga gcaagtttga catcaaaagt gatatttgtt gatagcttgt
     4981 ctgggtaaat ctgagcaaac catgagaaag ctccttcaaa ggctggatcg ccagttccca
     5041 aaagaacaat ctgaacatct tcttgcaaga tatggtgaag actttcgacc accacatcaa
     5101 aacctttttg acgtgtcaaa cgagaaacaa ttcccaccag tggaacgtct gctctaacag
     5161 gcaagccaac tctttcttgc aattttgcct tatttttggc tttcccagac aaatcttcct
     5221 gattgaaatg atagtctaaa agagcatccg tctgaggatt ataaagatca gcatcaatcc
     5281 cattcacgat accagatact ttaccagact ccattttaag aatctgatcc aaattacatc
     5341 caaactgact agtcataatt tcatgagcat agctaggtga aacagttgaa acacggttcg
     5401 catagagaat acctgccttc atccagttca gacagttgtt ccatcgaagg gtgccatcag
     5461 cgtaacgttc aaagccaact ccaaacaaat cacccaacat tccttctgaa aattgtcctt
     5521 ggaattctaa attatgaatg gttaaaactg tttcaatgtc ctcataggct tgaatccaac
     5581 ggtatttttc cttcaacaag aaaggaatca tagctgtatg gtagtcatga acatggagaa
     5641 gatcaggaat aaagtcaatc ctttccatag cctcaatggc agccagttgg aaaaaggcaa
     5701 agcgttctcc gtcatcaaaa tcaccgtaaa catgaccacg gaagaaataa tattgattgt
     5761 caataaagta gaaggttaca ccatttaata ctgttttctt aattccacaa tactgtctgc
     5821 gccaaccaac gctcacctca aaatgaagca catcttcaat ctgacttcca aatttagcct
     5881 ctaccatatc atagtagggt aaaatcactg caacttcgtg cccagctttt accagtgatt
     5941 ttggaagagc gccaatgacg tctcccaaac cacctgtttt tgaaaagggt gcaccctctg
     6001 ctgctacaaa taaaattttc atgaatgaat atcctctgtt actttagcac ctttcttaac
     6061 cacaactgga tgttctgcag ttcctcgaat cacaacacca ggctcaactt caaccccttt
     6121 gtccaagata gcatattcga cctgagcccc ttctccaata acaacacgag ggaagagcag
     6181 gctatcttta accaagctat ccttatggac atgaatatta cgtgatagaa cagaattagc
     6241 tacttgacct tcaataatac taccagaggc aaactgagaa gtgcttacct tagatgtatt
     6301 agcatagtaa gttggctctt cgtttttgac ctttgtataa atcttttggt ttggtgagaa
     6361 aagagaatag aatttttgtg attcaagcat atcgatattc gcttgataat aagatttaac
     6421 agagtgaata ttggctagat agcccgtgta ctcgtaggcg aaagctccct cttttacagc
     6481 caaatcccgt aaaacatagc gcaatttctc tggatgttct tttttagctt cttcttccaa
     6541 gtgttcaatc aaccaaggtg tatcaacgac aaagatatct gtagacatat tgaacgtttc
     6601 agctgttgac ttgctatcaa agagtttatg agaaagaaca tggtctgttt catctacatc
     6661 caagattgca tttacttctg aaatatcttt cttagctagt tttttataaa ctacagtgat
     6721 aggctctttt gttgtactat gtaggtggaa aacttggttc aaatcaatgt taataagaac
     6781 atcgcagttg agggcaaccg tttggtttga gccagaacgt ttcaaataag taagaagctg
     6841 ttggtagtat tcttttccaa ctgtactact ttctacacgg gtattgtaaa ttcctagata
     6901 gtaatggcta agaagggttg ataagcccca ctcgcgtcct gaacgaatat ggtcaaatac
     6961 tgagctgata ttatcctgct ggaaaatacc aaagacacta cgaacacctg cattagcaag
     7021 gcttgaaagt gggaagtcaa tcaaacgata tttcccacca aatggcaaac ttgctactgg
     7081 acggtggtcc gtcaatgtcg acatattgtg aaaaccaact gtatttccta aaatggcaga
     7141 atatttatca atcttcatct gttgctaccc ccactacttc attatatcct acaacttgta
     7201 cttcatctgt tccatcaatt tcgacaccgt cagaaataat cgcaccttca ccaataatgg
     7261 cacgtttaat cttagctcct tgaccaatga tagctccact catgataact gaatcaagga
     7321 cttccgctcc ttcgcgaact tgcgcgcctg ttgaaaggat agaatgttta acagttccat
     7381 caacgaaaca tccgtctaca actaatgagt cttccacatg agcatttgcc ccgaggaagt
     7441 ttggtggtga aatcaagttt cttgagtaaa tcttccattg acggttacga ctatccaagg
     7501 cattttctgg agaaatatac tccatgttcg cttcccaaag tgactcaata gtaccaacat
     7561 ctttccaata accactaaat tcataagcat aaacactttc acctgactca aggtaatttg
     7621 gaatgacatt tttaccaaag tctgacatgc caaccttgct cttttcagca gcgactaaca
     7681 tattacgaag gcgttgccaa tcaaaaatgt agattcccat agaagctttt gtagatttag
     7741 gttgagctgg tttttcttca aattcaacaa tacgattgtt agcatctgtg ttcatgatac
     7801 caaaacggct tgcttcttta agagggacgt ctaaaactgc tactgtcaag ctggcattat
     7861 tatccttatg agactggagc atatcatcat agtccatttt gtagatgtgg tccccagaca
     7921 aaatcaagac atactcagga ttgacactgt cgatatagtc gatattttgg taaatagcgt
     7981 gactagtccc ctcaaaccaa cgatttcctt cacttgcaga ataaggttga agaatagaga
     8041 cacctgaatt aataccgtct agtccccagc ttgaaccatt cccaatatgg ttgttgagag
     8101 caagtggttg atactgtgta acgaccccaa cattatgaat ccctgagttg gcacagtttg
     8161 atagggcaaa gtcaatgata cggtagcgcc caccaaattg cacagctggt tttgcgatgc
     8221 tttgagtgag tttaccgaga cgagttcctt gcccaccagc aagaatcaaa gctaacattt
     8281 catttttcat tttctactcc tttttggttt ttatttgtga cggttttagt agatttcaag
     8341 cgacgtttga ttttccatac acttgctccc atagccggta gagtaaaggt taaggtctgc
     8401 tcataatctt tccatagtcc ttcttgcgtt tgaacagttt gattatgttc tttccaaacg
     8461 cctccccact cttccaactc agtattccat acttcttcgt aaattcctgc aacgggtagt
     8521 ccgattgtaa aatctttccg ctcaacaggt accatattaa agatacagac taacatttct
     8581 ccctttttac ccttacgaat aaaggaaaga acactctggt ctcgattatc cgcatcaatg
     8641 atttcaatac catcatagct ggtatcaatt tcccacagac agcgatgatc tttgtaaaac
     8701 tggtttagct gagaagcgaa atacttcatc ttagcattca ttgggtcttc taggttagac
     8761 cattccaact gttcttcaga tttccattct aggaattgac cgtattcgct acccatgaag
     8821 agcaatttct taccagggtg acaaatttgg tacgtataga gattgcgcaa gcctgcgaat
     8881 tgattgtaac gatctcccca catcttatgc atcatactct tcttgccatg aaccacttca
     8941 tcgtgcgaga atggcaagag ataattctcc ttgaaaacat acataaagct gaaagtcacc
     9001 aggttaaagt catatttacg ataaatcgga tcttcttcgt agaaacggag gatatcattc
     9061 atccagccca tgttccattt gtagtcaaat cctagactac caatctcttt cattcccgta
     9121 atcttggtcg cagacgaact ttcttctgca atcatcatca catctggata ttctaactta
     9181 ataacttcat tcaagcgttg aagaaaataa taaccttcat agttgagatt tccgccatct
     9241 ttattaggtg tccatggagc attatcatag tccaaataga gcatgttgct aacagcatcc
     9301 acacgaatac catccaaatg atagacatca atccaatgct taatgcaaga aattaagaag
     9361 gactggactt cattttttcc aaggtcaaaa ttaagggcac cccaaccatg gttatgagcc
     9421 ttattatggt cttggtattc aaaagtcggt gtcccatcat aataggctaa ggcatcatcg
     9481 ttgatggtaa agtgacctgg tacccagtcc acaataaccc caatattatg ggtatgacac
     9541 tcctcgacaa aatcttgaaa ctcctctggt ctgccataag catgctctaa agcgaagtaa
     9601 cccataagct gataccccca actcaagccc aaaggatggg acatcaaggg cataaactca
     9661 atatgagtat agttcatttc aacgagataa ggaatgagtt catccttgag ctgggcaaaa
     9721 ctataaggac tgccatcaga atttcttttc catgatccag cgtgaacttc ataaatattg
     9781 acaggacgct cttcaaagcc ccaacgtttt cttcgtgcca gccaaagtcc atccttccat
     9841 ttcttctcag gaagctctgt taagattgcc cctgttcctg gacgagcctc atacctgaca
     9901 gcaaaagggt caatcttcat cagttgatga ccattttgac gtgtgacatg atatttgtaa
     9961 atatgccctt cttgagccat attggtaaag acttcccaga ccccaaaatc atttcttacc
    10021 attggaatct gattttcaat ccagttggta aaatcaccaa ccaagtgaac agcctgagca
    10081 ttaggtgccc aaacacggaa ggtatagcca tgctctccat ttagttcttc cctatgtgct
    10141 cctagataat gttggagata aaaattttca cccgtcataa aggtttttaa tgcttctcta
    10201 ttatccatat actccccttc tcctgtaagc gttttctatg tttttattat actacctttt
    10261 tagagaagat tcaagtaaat tactatactt ctttaattat tttgaaaatc tacaacaagt
    10321 tcacttactc gttcaattgt aaatcaatat tttttcaaaa aattgcgaaa acgcctttct
    10381 ttttctacta tagtgaaatg aaataaaaca tgcgcaagtc gattaaggaa tttaatctaa
    10441 tttctaacaa tgtcttagaa atcaaagtgt actattttaa cttcaatgt
//
LOCUS       DAVBOG010000067         9806 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.068, whole genome shotgun sequence.
ACCESSION   DAVBOG010000067 DAVBOG010000000
VERSION     DAVBOG010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9806
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.068"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            198..293
                     /locus_tag="VQ865_001923"
                     /pseudo
     CDS             198..293
                     /locus_tag="VQ865_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(546..1166)
                     /locus_tag="VQ865_001924"
     CDS             complement(546..1166)
                     /locus_tag="VQ865_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000780815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HET3136220.1"
                     /translation="MKLYFVRHGRTLWNQEGRFQGASGDSPLLPESIETLKRLGQYLK
                     EIPFDQIYSSDLPRAVKSAEIIQSQLHTPCSLEIVPNLREWQLGKLEGLKIATLEAIY
                     PQQIQAFRSNLAQFDTRMFGAESLYSTTQRTIQFIKSLKDSPAERILIVGHGANLTAS
                     LRTLLGYKEPLLRKDGGLANASLTIIETHDFETFTLNTWNDTSYQS"
     gene            complement(1166..1648)
                     /locus_tag="VQ865_001925"
     CDS             complement(1166..1648)
                     /locus_tag="VQ865_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HET3136221.1"
                     /translation="MAKKVKIKKTLVEQILSKAAIPHQGIQINALEGELPQGYERDQI
                     FKTLALLGDKTGPIIGIVPITQHLSEKKLAKISGNKKVSMIPQKDLEKTTGYIHGANN
                     PVGIRQKHNYPIFIDKIALDLDRMIVSAGEVGHSIIVAPQDLASFVKADFVDILEDIK
                     "
     gene            complement(1648..2490)
                     /locus_tag="VQ865_001926"
     CDS             complement(1648..2490)
                     /locus_tag="VQ865_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004256605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HET3136222.1"
                     /translation="MLSWLARVIKGIVIALGFILPGISGGVLAAILGIYERMIGFLAH
                     PFKDLKENVLYFIPVAIGMLLGIGLFSYPIEYLLENYQVFVLWSFAGAIIGTVPSLLK
                     ESTRESDRDKIDLAWLWTTFIISGLGLYALNFVVGTLSASFLNFVLAGALLALGVLVP
                     GLSPSNLLLILGLYAPMLTGFKTFDLLGTFFPIGIGAGATLIVFSKLMDYALNNYHSR
                     VYHFIIGIVLSSTLLILIPNAGNAESIQYTGLSLVGYVIIAFFFALGIWLGIWMSQLE
                     DKYK"
     gene            complement(2585..3385)
                     /locus_tag="VQ865_001927"
     CDS             complement(2585..3385)
                     /locus_tag="VQ865_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001866725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HET3136223.1"
                     /translation="MRKQIHPLILFSFFGIMMFILIINRPLNDNQSFKTKSNIAQIEA
                     QALKHLDKPIIDLSGWQRPEEINYDALSQNISGAIVRVHSGAQTTKENDASFINGIDK
                     AYKSHITELQKRNVPVAVYAYVAGKSVQEMEKAAEVFYNAASPYSPSYYWLDVEDKTM
                     SNMNEGVENFRAKLASLGAKNIGIYVGVYFMEEHSIDTGKFTSVWIPSYGSDSGFLES
                     SPKTDLDYDIHQYTSKGKIAGFDHDLDINVISPLKNKEETFRKLFLKP"
     gene            3529..4908
                     /gene="glmU"
                     /locus_tag="VQ865_001928"
     CDS             3529..4908
                     /gene="glmU"
                     /locus_tag="VQ865_001928"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000073762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HET3136224.1"
                     /translation="MSNFAIILAAGKGTRMKSDLPKVLHKVAGISMLEHVFRSVGAIQ
                     PEKTVTVVGHKAELVEEVLAGQTEFVTQSEQLGTGHAVMMTEPILESLSGHTLVIAGD
                     TPLITGESLKNLIDFHINHKNVATILTAETDNPFGYGRIVRNDNAEVLRIVEQKDATD
                     FEKQIKEINTGTYVFDNKRLFEALKNINTNNAQGEYYITDVIGIFRETGEKVGAYTLK
                     DFDESLGVNDRVALATAESVMRRRINHKHMVNGVSFVNPEATYIDIDVEIASEVQIEA
                     NVTLKGQTKIGAETVLTNGTYVVDSTIGAGAVITNSMIEESSVADGVTVGPYAHIRPN
                     SSLGAQVHIGNFVEVKGSSIGENTKAGHLTYIGNCEVGSNVNFGAGTITVNYDGKNKY
                     KTVIGDNVFVGSNSTIIAPVELGDNSLVGAGSTITKDVPADAIAIGRGRQINKDEYAT
                     RLPHHPKNQ"
     gene            4918..5463
                     /locus_tag="VQ865_001929"
     CDS             4918..5463
                     /locus_tag="VQ865_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000393791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3136225.1"
                     /translation="MEFEEKTLSRKEIYQGPIFKLVQDQVELPEGKGTAQRDLIFHNG
                     AVCVLAVTDEQKLILVKQYRKAIEAVSYEIPAGKLEVGENTAPVAAALRELEEETAYT
                     GKLELLYDFYSAIGFCNEKLKLYLASDLTKVENPRPQDEDETLEVLEVSLEEAKELIQ
                     SGHICDAKTIMAVQYWELQKK"
     gene            5475..5789
                     /locus_tag="VQ865_001930"
     CDS             5475..5789
                     /locus_tag="VQ865_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="foldase"
                     /protein_id="HET3136226.1"
                     /translation="MGKSLLTDEMIERANRGEKISGPPLLDDNEETKILPTSSSRFGY
                     ANPKDHGFSQETLKIQVEPSIHKSRRIENTKRNVFNSKLNKILFAVIFLLILLVLAMK
                     LL"
     gene            5806..6498
                     /locus_tag="VQ865_001931"
     CDS             5806..6498
                     /locus_tag="VQ865_001931"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HET3136227.1"
                     /translation="MKIGIIAAMPEELAYLVQHLDNAQEQVVLGNTYHTGTIVSHEVV
                     LVESGIGKVMSAMSVAILAVHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDVDV
                     TAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDSFVAGNDKIEA
                     IKSHFPEVLAVEMEGAAIAQAAHALNLPVLVIRAMSDNANHEANIFFDEFIIEAGRRS
                     AQVLLTFLKALD"
     gene            6575..7066
                     /gene="rocS"
                     /locus_tag="VQ865_001932"
     CDS             6575..7066
                     /gene="rocS"
                     /locus_tag="VQ865_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein RocS"
                     /protein_id="HET3136228.1"
                     /translation="MSIEMTVSEIAEVLGLSRQAINNRVKELPEEDTDKNDKGVTVVT
                     RSGLIKLEEIYKKTIFEDEPVSEDVKQRELMEILVDEKNAEILRLYEQLKAKDRQLSE
                     KDEQMRIKDRQIAEKDKQLDQQQQLTLQAMKDQENLKLELDQAKEEVQSTKKGFFARL
                     FGG"
     gene            7140..7730
                     /locus_tag="VQ865_001933"
     CDS             7140..7730
                     /locus_tag="VQ865_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' exonuclease"
                     /protein_id="HET3136229.1"
                     /translation="MERLEDYIAFDLEFNQHEGQTHLIQVSAVRFRDGREIDAYDSYV
                     HTSVPLKSFINGLTGITAETLKDAPPVEKVLEEFQEFVGSLLMIGYNAAKSDLPILAE
                     HGLDYSQQYKVDLYDEAFERRSSDLHGIANLKLQTVASFLGFQGQSHNSLEDARMTAR
                     VYESFLESDQARELLETESSLSNNPFGVLDLSQLFD"
     gene            7739..9502
                     /locus_tag="VQ865_001934"
     CDS             7739..9502
                     /locus_tag="VQ865_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000801733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HET3136230.1"
                     /translation="MKPEKPKKLGLKQIYLNLDKILFLFFLIFMIVEYLWVPFNSWLA
                     SFLLDQTGYLFISYNNVLAILTHSPLISLAFLALIVINLLVAYFQIGLLFIGARHLLY
                     NEKRRLIEYIRKVFHESFGFMKKLTGAKALFIFFYIAMLFPFIRKMLKIYYLNKIVIP
                     EFIQAYLEDRYWMWWLSILLLSLIFLYVSVRLMFALPKIVYDQLTVREAVMFSLEKTK
                     KRVTFYAWNLFYILLKAHLLFYLPLIPLLLAQTLVDDITQRESLILGILNFVVIKNLY
                     YMALTYFLVKFVSFLTGKELDMLPRREKDHIVRWGVMTCASLFFALEGYIYLEAPMVH
                     LPQLISHRGVSNANGIQNTVESLETTAQLKPDLVETDVQETKDGQFVMMHDANLKNLA
                     GINKSPQDLNLEELKGIDIFENGYQTKISSFEDYLSRANELGQKLLIEIKTSKKDSPD
                     MMNRFLARYAAKLKIYGHQIQSLDYHVVEKVRQYDAELPVYFIMPYNSVFPKTRATGY
                     TMEYSTLDEYFVSKLWTTDQKLYVWTVNDSEAISKSLHLGVDGVITDDLEKVQREIEV
                     AQEDPEYTDLLLKKALEFFEF"
     gene            9716..>9806
                     /locus_tag="VQ865_001935"
     CDS             9716..>9806
                     /locus_tag="VQ865_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
                     /protein_id="HET3136231.1"
                     /translation="MAYSIDFRKKVLSYCERTGSITEASHVFQI"
BASE COUNT         3037 a         1703 c         2084 g         2982 t
ORIGIN      
        1 taattttaaa gactttttga ccagcctcat ttttttaact tgatactcag tgaaaagcaa
       61 agattaaact aggaagctag ctgtaggctg ctcaaagaac agctttgagg ttgcagataa
      121 aacttgtgag gtaaccaaca tatataatgt gaagctgacg tggtttgaat agattttaga
      181 agggtatgag tctggaagtt ttaatggata atgcaagatt ccatagaatg ggtaagctag
      241 agttcttatg tgaagagttt gggcataaac ttttaccttt tcctccctac tcatattagt
      301 atagaaaagt gaatctaaaa tagtacataa ctgcttctaa aacattctta taaattgatt
      361 taaattctca aatcatatta ttcagttctt atttcatttt gctctacaat cctgttgaga
      421 agacacgtgt tcatatcaaa aaggtattgg caagttgaaa taccttttta caaggttctt
      481 ttgtcttatt tttgtttcaa ctgactatat ctcctatggt tctagttcag aaggctaggc
      541 tataattatg attgataaga agtatcattc caagtattga gagtgaatgt ttcaaaatca
      601 tgggtttcta taatggtcag gctggcattt gctagaccgc catctttacg aagaagtggt
      661 tctttatagc ctaggagagt acgaagactg gcagtaagat tggcgccgtg tccgacaatt
      721 agaatacgct cagctggact atcttttaat gatttgataa attggatggt ccgctgagtt
      781 gtactataga gggattcggc tccgaacatt cgagtgtcaa attgagcaag atttgaacga
      841 aaagcctgga tttgttgcgg gtaaatagct tccagggttg caattttcaa accttctaac
      901 ttcccaagtt gccattcacg gagattagga acgatttcta aagaacaggg ggtatggagt
      961 tgactttgga taatctcagc agatttgacc gctcgaggta aatcacttga ataaatctga
     1021 tcaaaaggaa tttccttgag atactgacca agtcgtttta gggtttcaat ggattcagga
     1081 agaagaggag aatcaccgct agcaccttga aaacgacctt cttggttcca gagggtacga
     1141 ccgtggcgga caaagtagag tttcattact tgatgtcctc caaaatatct acaaaatctg
     1201 cctttacaaa gctagccaag tcttgtggcg cgacgataat gctgtgtccg acttcgcctg
     1261 cagagacaat cattcgatcc aaatctagag caattttatc gataaaaatg ggataattgt
     1321 gtttctgacg aattccgaca ggattattgg ctccatgaat gtaaccagtt gttttttcta
     1381 agtccttttg tggaatcatg ctcacttttt tattgccaga aattttagct agtttctttt
     1441 cagacaagtg ctgagtgata gggacaattc cgataatcgg tccggtcttg tctcccaaaa
     1501 gcgccaaggt tttgaaaatc tgatctcgtt cataaccttg aggaagctct ccttctaggg
     1561 cattgatttg aatcccctga tgagggatag ctgctttaga taggatttgt tccaccaatg
     1621 tttttttgat tttaactttt tttgccatta tttatattta tcctccaatt gactcatcca
     1681 aataccaagc cagattccca gcgcaaagaa gaaggcgatg atgacataac cgacaagtga
     1741 aagtcctgtg tattggatac tttcagcgtt tcctgcattt ggaattaaga tcaaaagggt
     1801 acttgatagg acgataccga tgatgaaatg atagacgcgt gagtggtagt tgtttaaggc
     1861 ataatccatc aattttgaaa aaacgatgag agttgcacct gcaccaattc caatcggaaa
     1921 gaaggttccc aagagatcaa aagttttaaa accagtcaac ataggagcat agagtcccaa
     1981 aatcaaaagt aaattcgatg ggctgaggcc aggaaccaag acgccaaggg ccaatagtgc
     2041 gcctgctagg acgaagttaa gaaagctggc gcttaaggtt ccaacgacaa aatttaaggc
     2101 atatagtcct aatccagaaa tgataaaggt tgtccataac caagctaaat caatcttgtc
     2161 tcggtcagat tctcgagttg attctttgag gaggctagga actgtaccga taatagctcc
     2221 cgcaaagctc cataatacaa agacctgata attttcaagc aggtattcaa tcgggtagga
     2281 aaataagccg attcccagaa gcataccgat ggcaactgga ataaagtaca aaacattttc
     2341 tttaaggtct ttaaagggat gggccagaaa gccaatcatt cgttcataga ttcctaagat
     2401 tgctgctaga actcctccgg aaattcccgg taggataaat ccaagagcaa ttacaatccc
     2461 tttaataacg cgtgctaacc atgagagcat atatttcctc caactatttc tatttcaaaa
     2521 aatccttact atattgtatc acaatcagac acaaaaagaa aaagcaaatg ataaacaaat
     2581 gcttttaagg ttttaaaaaa agctttcgaa aggtttcttc tttatttttt aagggagaga
     2641 taacgttgat atctaaatcg tggtcaaagc cggcaatttt tcctttagat gtgtattggt
     2701 gaatatcata atctaaatca gttttaggac tgctctccaa aaatcctgag tctgagccgt
     2761 aggacggaat ccaaacagag gtaaacttgc ctgtatcaat actgtgttct tccatgaagt
     2821 agacaccaac gtagatgccg atgtttttag cacctagtga tgctagtttt gctcgaaagt
     2881 tttcgacacc ttcgttcata ttagacatgg ttttgtcttc cacgtcaagc caatagtaac
     2941 tagggctgta aggagaggca gcattgtaga aaacttcggc agccttttcc atttcttgga
     3001 cactttttcc agctacataa gcgtagacag caactgggac attccgcttt tgaagttcag
     3061 tgatatgact cttataggcc ttgtctattc cattgataaa tgaagcatca ttttcttttg
     3121 tcgtttgagc accactgtga acacgaacaa tagcacctga aatattttgt gagagggcat
     3181 cgtagttgat ttcctcagga cgctgccagc cagagaggtc aataatcggt ttgtctaagt
     3241 gtttcaaagc ctgtgcttca atctgtgcta tattggattt tgttttaaac gattggttgt
     3301 cattaagtgg gcgattgatg attaaaatga acatcataat cccaaaaaaa ctaaataaaa
     3361 taagtggatg aatttgtttt ctcatatctt ataattctac cctaaaaatc aaaaaaaatc
     3421 aaaaaaatgg gttaaggaag agactttaga gcattttttc attcaagagt gcggaatgat
     3481 ttgaaatatg gtataataaa agggaatttc tacagaaaag agaagattat gtcaaatttt
     3541 gccattattt tagcagcggg taaagggact cgcatgaaat ctgatttgcc aaaagttttg
     3601 cacaaggttg cgggtatttc tatgttggaa catgttttcc gtagtgtggg agctatccaa
     3661 cctgaaaaga cagtaacagt tgtaggacac aaggcagaat tggttgagga ggtcttggct
     3721 ggacagacag aatttgtgac tcaatctgaa cagttgggaa ctggtcatgc agttatgatg
     3781 acagaaccta tcttagaaag tttgtcagga cacaccttgg tcattgcagg agatactcct
     3841 ttaatcactg gtgaaagctt gaaaaacttg attgatttcc atatcaatca taaaaatgtg
     3901 gccactatct tgactgctga aacggataat ccttttggct atggacgaat tgttcgtaat
     3961 gacaatgctg aggttcttcg tattgttgag cagaaggatg ctacagattt tgaaaagcaa
     4021 atcaaggaaa tcaacactgg aacatacgtc tttgacaaca agcgtttgtt tgaggctttg
     4081 aaaaatatca ataccaataa cgctcaaggc gaatactata ttacagacgt cattggtatt
     4141 ttccgtgaaa ctggtgaaaa agttggcgct tatactttga aagattttga tgaaagtctt
     4201 ggggtaaatg accgtgtggc gcttgcgaca gctgagtcag ttatgcgtcg tcgcatcaat
     4261 cataaacaca tggtcaacgg tgttagcttt gtcaatccag aagcaactta tatcgatatt
     4321 gatgttgaga ttgcttcgga agttcaaatc gaagccaatg ttaccttgaa agggcaaacg
     4381 aaaattggtg ctgagactgt tttgacaaac ggtacttatg tagtggacag cactatcgga
     4441 gcaggagcgg tcattaccaa ttctatgatt gaggaaagta gtgttgcaga cggtgtgaca
     4501 gtcggtcctt atgctcacat tcgtccaaat tcaagtctgg gtgcccaagt tcatattggt
     4561 aactttgttg aggtgaaagg atcttcaatc ggtgagaata ccaaggctgg tcatttgact
     4621 tatatcggaa actgtgaagt gggaagcaac gttaatttcg gtgctggaac tattacagtc
     4681 aactatgacg gcaaaaacaa atacaagaca gtcattggag acaatgtctt tgttggttca
     4741 aattcaacca ttattgcacc agtagaactt ggtgacaatt ccctcgttgg tgctggttca
     4801 actattacta aagacgtgcc agcagatgct attgctattg gtcgcggtcg tcagatcaat
     4861 aaagacgaat atgcaacacg tcttcctcat catcctaaga accagtagga gcctatcatg
     4921 gagtttgaag aaaaaacgct tagccgaaaa gaaatctatc aaggaccaat atttaaactg
     4981 gtccaagatc aggttgaatt accagaaggc aagggaactg cccaacggga tttgattttc
     5041 cacaatgggg ctgtctgtgt tttagcagta acggatgaac aaaaacttat cttggtcaag
     5101 cagtaccgca aagctatcga ggctgtctct tacgaaattc cagccggaaa attggaagta
     5161 ggagaaaaca cagcccctgt cgcagctgcc cttcgtgaat tagaggaaga aacagcctat
     5221 acagggaaat tagaactctt gtacgatttt tattcagcta ttggcttttg taatgagaag
     5281 ttaaaactat atttagcaag cgatttgaca aaagtggaaa atccgcgtcc gcaggatgag
     5341 gatgaaacct tggaagtcct tgaagtgagc ttagaagaag cgaaagaatt aatccaatca
     5401 ggtcatatct gtgatgccaa gacaattatg gctgttcagt attgggagtt gcagaaaaaa
     5461 tagaggaggt cagtatgggt aaatctttat taacggatga aatgattgaa agagctaata
     5521 gaggcgaaaa aatttcaggt cctcctttgc tggatgataa tgaggaaact aagattttac
     5581 caacctcttc ttcccgtttt ggttatgcca atcctaagga tcatggtttt agccaggaaa
     5641 ccttgaagat tcaggtcgaa ccatctattc ataaaagccg tcgcattgaa aataccaaga
     5701 gaaatgtctt caattctaag ttgaataaaa tcttattcgc ggtcatcttt ctcttgattt
     5761 tgcttgtttt agcaatgaaa cttttgtaat agaaaaggaa ttgaaatgaa aataggaatt
     5821 attgctgcta tgccagaaga actggcttat ctggtccagc atttagacaa tgcccaggag
     5881 caagttgttt tggggaatac ctatcataca ggaaccattg tttctcatga agtcgttctt
     5941 gtagaaagtg gaattggtaa ggtcatgtct gctatgagtg tggcgatttt ggctgttcat
     6001 ttccaggtgg atgcccttat taatacgggt tcagctgggg cagtagcaga aggtatcgct
     6061 gttggggatg tcgtgattgc tgacaaatta gcctatcatg acgtggatgt cacagctttt
     6121 ggctatgctt atggacaaat ggcgcaacaa ccgctttatt tcgaatcaga caaaaccttt
     6181 gttgctcaaa tccaagagag tttatctcaa ttggaccaaa actggcatct tggtttgatt
     6241 gctacaggag atagttttgt tgcaggaaat gacaagatag aagcgattaa gtcccatttc
     6301 ccagaagttt tagccgtgga gatggagggg gcagctattg ctcaagcagc gcatgccctc
     6361 aatctcccag tcttagtcat cagagctatg agtgacaatg ccaaccatga agcaaacatc
     6421 ttttttgatg agtttattat cgaagctgga cgtcgctctg cccaagtctt gttgaccttt
     6481 ttgaaggctt tagattaagc ggaaatttga cagtttttct agcttatgat aagatttaag
     6541 taaagaaaag ctagaaaacg tttcagagga tattatgagt attgaaatga ccgtcagtga
     6601 gattgcagag gtcttaggat tatctcgcca agcaatcaat aaccgtgtca aagaattacc
     6661 agaagaagac acagataaaa atgacaaagg ggtaacagtt gttaccagaa gtggcttgat
     6721 taagctagaa gaaatctata aaaaaacgat ttttgaagat gagcctgtca gtgaagatgt
     6781 caaacaacgt gaactgatgg agattctagt ggatgagaag aatgcagaaa ttcttcgtct
     6841 ttatgaacaa ttaaaagcca aggatcgtca gttatcagaa aaagacgagc agatgcgtat
     6901 caaagaccgt cagattgctg agaaagacaa acaattagat cagcaacaac aattgaccct
     6961 tcaagccatg aaggatcaag aaaatcttaa gctagagctg gaccaagcaa aagaagaagt
     7021 ccaatccact aagaaaggct tttttgctcg tttatttgga ggataatcaa ggagctgttt
     7081 aggttaaatg ctaacctgat ggcttctttt gtttgtgaat agtagaggag aggtacagaa
     7141 tggaacgatt agaagattac attgcttttg acttagaatt taatcagcac gaaggacaaa
     7201 cacacttgat tcaagtatcg gcagtgcgtt ttagagatgg tcgggaaatc gatgcctatg
     7261 attcctatgt tcataccagc gtccctctaa aaagctttat caatggtttg accgggatta
     7321 cagctgagac cttaaaagat gctcctccag ttgagaaagt cttagaagaa ttccaagagt
     7381 ttgtgggttc tttgctgatg ataggctaca atgctgctaa aagtgattta cctattttag
     7441 cagagcatgg tttagactat agccaacagt acaaggtgga tttgtatgat gaagcttttg
     7501 aacgtcggag ttcagattta catggtattg ccaatctcaa attgcaaact gttgcctcat
     7561 ttcttggatt tcaaggtcag tctcataata gtttagagga tgctcggatg acggcgcgtg
     7621 tttacgaatc cttcttagag tcggatcaag ctagggaatt gttagagaca gaaagtagct
     7681 tatcaaacaa tccttttggt gtcttggact tgtctcaatt atttgactag gagtgcctat
     7741 gaaacctgaa aaacctaaaa aattgggtct taaacagatt tacctcaatc ttgataaaat
     7801 cctctttcta tttttcttga tttttatgat agtggagtat ttgtgggtac cattcaattc
     7861 atggttggct agcttcttat tagatcagac aggttatctt tttatttcct ataacaatgt
     7921 cttagccatc cttactcatt ctccattgat tagtctagct tttttagcct tgattgtaat
     7981 taaccttctg gttgcttatt ttcaaatagg actcctcttt attggtgctc gtcatctcct
     8041 ctataatgaa aagcgaaggc taattgagta tatccgcaag gttttccatg aaagttttgg
     8101 atttatgaaa aagctaactg gcgctaaagc cttgtttatc tttttctata tagctatgct
     8161 gtttcctttt atacggaaaa tgctgaagat ttattatctt aataaaatcg tcattccaga
     8221 gtttatccaa gcttatttag aagatagata ttggatgtgg tggctgagca tcctacttct
     8281 atctcttatc tttctctatg tctctgtcag attgatgttt gcccttccga agattgtata
     8341 tgatcagctg actgttcgag aagcagtgat gtttagcttg gagaaaacca agaagagagt
     8401 tactttttat gcttggaatt tattttacat cttgctcaaa gcacatttat tattttatct
     8461 tcctttgatt cctttattat tggctcaaac tttggtagat gatatcactc agagagagtc
     8521 tctgattctt ggtattttga attttgtcgt gattaaaaat ctctattata tggctctgac
     8581 ttattttttg gttaaatttg tttcattttt gacaggaaag gagctggata tgcttcctag
     8641 gagagaaaaa gatcacatcg tgcgatgggg tgtcatgact tgtgccagtc ttttctttgc
     8701 cttagaaggt tatatttatc tggaggctcc catggttcat ctacctcaac ttatttctca
     8761 ccgaggggtt tccaatgcaa atgggattca aaatacagta gagtccttgg aaactacagc
     8821 acaactcaaa ccagacttgg tggagacgga cgtgcaggaa acaaaagatg ggcagtttgt
     8881 catgatgcat gatgctaact tgaaaaatct agcaggtatc aataaaagtc ctcaagactt
     8941 aaacttggag gagcttaaag ggattgatat ttttgaaaat ggctaccaga ctaaaatttc
     9001 aagctttgaa gattatctca gtcgagccaa cgaacttggt caaaaattac taattgaaat
     9061 taaaaccagt aaaaaagata gtccagacat gatgaaccgc tttttagccc gttatgctgc
     9121 aaagctcaag atttatggac atcaaatcca gtctttagac taccatgttg tcgaaaaagt
     9181 aagacagtat gatgccgaac tgccagttta tttcatcatg ccctacaatt ctgtctttcc
     9241 taaaacaaga gcgacaggat atactatgga gtactcaacc ttggatgaat attttgtaag
     9301 caaactatgg acaacggatc agaaacttta tgtctggact gtcaatgatt cagaagctat
     9361 cagcaaatct cttcacttag gagtagatgg agtgattaca gatgatttgg aaaaagttca
     9421 gcgggaaata gaagtagccc aagaagatcc agaatatacg gatttgctct tgaaaaaagc
     9481 attggaattc tttgaatttt agtaataaaa aagaggaacg gttgttcctc ccatgatagg
     9541 taagtattct tgtgaatgct tgcttttttg tggttgcaat ccgtttacga gaattgtttg
     9601 tattgttctt gtttcaattt actttatagt gctttgaagt tggaatgcta cactataact
     9661 tataaaatat agtaaaatga accaaaaata gtacacaatg tggtataatc tttttatggc
     9721 atattcaata gattttcgta aaaaagttct ctcttattgt gagcgaacag gtagtataac
     9781 agaagcgtca cacgttttcc aaatct
//
LOCUS       DAVBOG010000068         9740 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.069, whole genome shotgun sequence.
ACCESSION   DAVBOG010000068 DAVBOG010000000
VERSION     DAVBOG010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 9740)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9740)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9740
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.069"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            89..1027
                     /gene="msrB"
                     /locus_tag="VQ865_001936"
     CDS             89..1027
                     /gene="msrB"
                     /locus_tag="VQ865_001936"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HET3136232.1"
                     /translation="MAEIYLAGGCFWGLEEYFSRISGVLETSVGYANGQVETTNYQLL
                     KETDHAETVQVIYDEKEVSLREILLYYFRVIDPLSINQQGNDRGRQYRTGIYYQDEAD
                     LPAIYTVVQEQERMLGRKIAVEVEQLRHYILAEDYHQDYLRKNPSGYCHIDVTDADKP
                     LIDAANYEKPSQEVLKASLSEESYRVTQEAATEAPFTNAYDQTFEEGIYVDITTGEPL
                     FFAKDKFASGCGWPSFSRPISKELIHYYKDLSHGMERIEVRSRSGSAHLGHVFTDGPR
                     ELGGLRYCINSASLRFVAKDEMEKAGYGYLLPYLNK"
     gene            1085..2809
                     /locus_tag="VQ865_001937"
     CDS             1085..2809
                     /locus_tag="VQ865_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136233.1"
                     /translation="MKHLLSYFKPYIKESILAPLFKLLEAVFELLVPMVIAGIVDQSL
                     PQGDQGHLWMQIGLLLIFAVIGVLVALIAQFYSAKAAVGFAKELTNDLYRHILSLPKD
                     SRDRLTTSSLVTRLTSDTYQIQTGINQFLRLFLRAPIIVFGAIFMAYRISAELTFWFL
                     VMVAILTIVIVGLSRLVNPLYSSLRKKTDQLVQETRQQLQGMRVIRAFGQEKRELQIF
                     QTLNQVYARLQEKTGFLSSLLTPLTYLIVNGTLLVIIWQGYISIQGGVLSQGALIALI
                     NYLLQILVELVKLAMLINSLNQSYISAKRIEEVFAESPENIHSELEQKQVTSGRVLQV
                     QELTFTYPDAAQPSLRDISFDMTQGQILGIIGGTGSGKSSLVQLLLGLYPVDKGNIDL
                     YQNGRSPLNLEQWRSWIAYVPQKVELFKGTIRSNLTLGLNQEVTDQELWQALEIAQAK
                     DFVSDKEGLLDALVEAGGRNFSGGQKQRLSIARAVLRQAPFLILDDATSALDTITESK
                     LLKAIRENFPNMSLILISQRTSTLQMADQILLLEKGELLAVGKHDDLMKSSQVYREIN
                     ASQHGKED"
     gene            2811..4559
                     /locus_tag="VQ865_001938"
     CDS             2811..4559
                     /locus_tag="VQ865_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000828810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136234.1"
                     /translation="MKRQTVNQTLKRLVVDLANHPFLLFLAFLGTIAQVGLSIYLPIL
                     IGQVIDQVLVAGSSPVFWQIFLQMLLVVIGNTLVQWANPLLYNRLIFSYTRDLRERII
                     HKLHRLPIAFADRQGNGEMVSRVTTDIEQLAAGLTMIFNQFFIGVLMILVSILAMLQI
                     HLLMTLLVLLLTPLSMVISRFIAKRSYHLFQKQTETRGIQTQLIEESLSQQTIIQSFN
                     AQTEFIQRLREAHDNYSGYSQSAIFYSSTVNPSTRFVNALIYALLAGVGAYRIMMGST
                     LTVGRLVTFLNYVQQYTKPFNDISSVLAELQSALACVERIYGVLDSPEVAETGKEVLT
                     SDQVKGAISFKHVSFGYHPEKILIKELSIDIPAGSKVAIVGPTGAGKSTLINLLMRFY
                     PISSGDILLDGQSIYDYTRVSLRQQFGMVLQETWLTQGTIHDNIAFGNPEVSREQVIA
                     AAKAANADFFIQQLPQGYDTKLENAGESLSVGQAQLLTIARVFLAIPKILILDEATSS
                     IDTRTEVLVQDAFAKLMKGRTSFIIAHRLSTIQDADLILVLVDGDIVEYGNHQELMDR
                     KGKYYQMQKAAAFSSE"
     gene            4816..6075
                     /locus_tag="VQ865_001939"
     CDS             4816..6075
                     /locus_tag="VQ865_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRZ/ATZ family protein"
                     /protein_id="HET3136235.1"
                     /translation="MKVFQHVNIVTCDQDFHVYLDGILAVKDSQIVYVGQDKPAFLEQ
                     AEQIIDYQGAWIMPGLVNCHTHSAMTGLRGIRDDSNLHEWLNDYIWPAESEFTPDMTT
                     NAVKEALTEMLQSGTTTFNDMYNPNGVDIQQIYQVVKTSKMRCYFSPTLFSSETETTA
                     ETISRTRSIIDEILKYKNPNFKVMVAPHSPYSCSRDLLEASLEMAKELNIPLHVHVAE
                     TKEESGIILKRYGKRPLAFLEELGYLDHPSVFAHGVELNEREIERLASSQVAIAHNPI
                     SNLKLASGIAPIIQLQKAGVAVGIATDSVASNNNLDMFEEGRTAALLQKMKSGDASQF
                     PIETALKVLTIEGAKVLGMENQIGSLEVGKQADFLVIQPQGKIHLQPQENMLSHLVYA
                     VKSSDVDDVYIAGEQVVKQGQVLTVEL"
     misc_feature    6151..6286
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            6325..6825
                     /locus_tag="VQ865_001940"
     CDS             6325..6825
                     /locus_tag="VQ865_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001287276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HET3136236.1"
                     /translation="MSEAIIAKKAELVDVVAEKMKAAASIVVVDARGLTVEQDTVLRR
                     ELRGSEVEYKVIKNSILRRAAEKAGLEDLASVFVGPSAVAFSNEDVIAPAKILNDFSK
                     NAEALEIKGGAIEGAVASKEEILALATLPNREGLLSMLLSVLQAPVRNVALAVKAVAE
                     SKEDAA"
     gene            6901..7269
                     /gene="rplL"
                     /locus_tag="VQ865_001941"
     CDS             6901..7269
                     /gene="rplL"
                     /locus_tag="VQ865_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HET3136237.1"
                     /translation="MALNIENIIAEIKEASILELNDLVKAIEEEFGVTAAAPVAVAAA
                     DAADAGAAKDSFDVELTSAGDKKVGVIKVVREITGLGLKEAKELVDGAPALVKEGVAT
                     AEAEEIKAKLEEAGASVTLK"
     gene            7456..7629
                     /locus_tag="VQ865_001942"
     CDS             7456..7629
                     /locus_tag="VQ865_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136238.1"
                     /translation="MQKKGQSSRQFVKSHLMTIMGVDIVKATQLVDEMEQVGLIRFDE
                     FGNVEILVLEGQS"
     gene            7626..8222
                     /locus_tag="VQ865_001943"
     CDS             7626..8222
                     /locus_tag="VQ865_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000822799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3136239.1"
                     /translation="MKRITASQYQTSERYYKLPKLLFESERYKNMKLEVKVAYSILKD
                     RLELSLNSGWIDEEGAVYLVFSNSKLMKLLGCSKSKLLSIKKTLREYGLIDEVQQSSS
                     EKGRMANKIYLGELEHEIPLVLHSDGASVKNRLGQSQKQTGPFLNSAPSETEESETDS
                     LFIEDEEERDTQPILKRKVEKVTKYDRDYIWGLVQDQF"
     gene            8259..8396
                     /locus_tag="VQ865_001944"
     CDS             8259..8396
                     /locus_tag="VQ865_001944"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136240.1"
                     /translation="MTDFERIYQYALDNVRFVRRAEVLAEFVFNGLYSVWNNRVRKGG
                     G"
     gene            8495..9740
                     /gene="dcm"
                     /locus_tag="VQ865_001945"
                     /pseudo
     CDS             8495..9740
                     /gene="dcm"
                     /locus_tag="VQ865_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000670032.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
BASE COUNT         2900 a         1839 c         2179 g         2822 t
ORIGIN      
        1 aaccatacct acggtaaggt gacgctgacg tggtttgaag agattttcga agagtattag
       61 ttaaaaacgt gataaaggag aaataaaaat ggcagaaatt tatctagcag gtggttgttt
      121 ttggggccta gaggaatatt tttcacgcat ttctggagtg ctagaaacca gtgttggcta
      181 cgctaatggt caagtcgaaa cgaccaatta ccagttgctc aaggaaacag accatgcaga
      241 aacggtccaa gtgatttacg atgagaagga agtgtcactc agagagattt tactttatta
      301 tttccgagtt atcgatcctc tatctatcaa tcaacaaggg aatgaccgtg gtcgccaata
      361 tcgaactggg atttattatc aggatgaagc agatttgcca gctatctaca cagtggtgca
      421 ggagcaggaa cgcatgctgg gtcgaaagat tgcagtagaa gtggagcaat tacgccacta
      481 cattctggct gaagactacc accaagacta tctcaggaag aatccttcag gttactgtca
      541 tatcgatgtg accgatgctg ataagccatt gattgatgca gcaaactatg aaaagcctag
      601 tcaagaggtg ttgaaggcca gtctatctga agagtcttat cgtgtcacac aagaagctgc
      661 tacagaggct ccatttacca atgcctatga ccaaaccttt gaagagggga tttatgtaga
      721 tattacgaca ggtgagccac tcttttttgc caaggataag tttgcttcag gttgtggttg
      781 gccaagtttt agccgtccga tttccaaaga gttgattcat tattacaagg atctgagcca
      841 tggaatggag cgaattgaag ttcgttctcg ttcaggcagt gctcacttgg gtcatgtttt
      901 cacagatgga ccgcgggagt taggcggcct ccgttactgt atcaattctg cttctttacg
      961 ctttgtggcc aaggatgaga tggaaaaagc aggatatggc tatctattgc cttacttaaa
     1021 caaataaaac agagagtggg gcttcccact ttcttcattt ctagaatatg aatagaaggg
     1081 atttatgaaa cacctattat cttacttcaa accctacatc aaggaatcaa ttttagcccc
     1141 cttgttcaag ctgttagaag ctgtttttga gctcttggtt cccatggtga ttgctgggat
     1201 tgttgaccaa tctttacctc agggagatca aggtcatctc tggatgcaga ttggcctgct
     1261 ccttatcttt gcagtaattg gcgttttagt ggccttgata gctcaatttt actcagcaaa
     1321 ggcagcagta ggttttgcta aggaattgac aaacgatctt tatcgtcata ttctttcctt
     1381 gccaaaggac agcagagacc gtctgacaac ttctagtttg gttactcgct tgacttcgga
     1441 tacctaccag attcagactg gtatcaatca attcctgcgt ctctttttac gagcgcccat
     1501 tatcgttttt ggtgccattt ttatggctta tcgaatctca gctgagttga ctttctggtt
     1561 cttagtcatg gttgccattt tgaccattgt cattgtaggg ttatctcgat tggtcaatcc
     1621 tctctacagt agtctcagaa agaaaacgga ccaactggtt caggaaacgc gccagcaatt
     1681 gcaagggatg cgggttattc gtgcttttgg tcaagaaaaa cgagagttac agatttttca
     1741 aacccttaac caagtttatg ctagattaca agaaaagaca ggtttcttgt ctagtttatt
     1801 aacacctctg acctatctga ttgtcaatgg aactcttctc gttattatct ggcaaggcta
     1861 tatttcaatt caaggaggag tactcagtca aggtgctctc attgctctta tcaattacct
     1921 cttacagatt ttggtggaat tggtcaagct agccatgctg atcaattccc tcaaccagtc
     1981 ctatatctca gccaagagaa tcgaggaggt ctttgcggaa tctcccgaaa acatccattc
     2041 agaattagaa caaaagcaag ttaccagtgg tcgggtttta caagtccaag aattgacttt
     2101 tacctatcct gatgcggccc agccttctct gagagacatt tcctttgata tgactcaagg
     2161 acaaatcctt ggtatcattg gggggactgg ttctggtaaa tcaagcttgg tgcaactctt
     2221 acttggactt tatccagtag acaaggggaa cattgacctt tatcaaaatg gacgtagtcc
     2281 tcttaatttg gagcagtggc ggtcttggat tgcctatgta cctcaaaagg tcgaactctt
     2341 taagggaact attcgttcca acttgacttt aggtttaaat caagaagtga ctgatcaaga
     2401 actctggcaa gccttggaga ttgcgcaagc taaggatttt gtcagtgata aggaaggact
     2461 cttggatgct ctagttgaag caggagggcg aaatttctca ggtggacaaa aacaaaggct
     2521 gtctatcgca cgagcagtct tgcgccaggc tccgtttctc atcctagatg atgcgacctc
     2581 agcactggac accattacag agtccaagct cttgaaagct attagagaaa attttccaaa
     2641 catgagctta attttgatct ctcaacgaac ctcgacttta cagatggcgg accagattct
     2701 cctcttggaa aaaggtgagt tgctagctgt tggcaagcac gatgacttga tgaaatccag
     2761 tcaagtctat cgtgaaatca atgcatccca acatggaaag gaggactaga atgaaacgac
     2821 aaactgtaaa ccagacgctc aaacgtttag tcgtagattt agcaaaccat cccttcctcc
     2881 ttttcctagc ctttctagga actattgccc aagttggctt atcaatttac ctacctattc
     2941 tgattgggca ggtcattgac caagtcctag tggctggttc atcaccagtt ttttggcaga
     3001 tttttctcca gatgctcttg gtggtaatag gaaatactct ggtacaatgg gccaatcctc
     3061 tcctctataa tcgtctaatc ttctcttata ccagagattt acgagagcga atcatccata
     3121 aactccatcg gttaccgatt gcttttgcgg atcggcaagg caatggagag atggtcagtc
     3181 gtgtaaccac ggatatcgaa cagttggcag ctggcttgac catgattttt aaccaatttt
     3241 tcattggtgt tttgatgatt ttggttagta ttctagccat gctccaaatt catctcctca
     3301 tgactctctt agtcttgctg ttgacgccac tgtccatggt gatttcacgc tttattgcca
     3361 agagatccta tcatctcttc cagaagcaaa cagagacgag gggaattcag actcagttga
     3421 ttgaagaatc gcttagccag cagactataa tccagtcctt caatgctcaa acagaattta
     3481 tccaaagatt gcgtgaggct catgacaact actcaggcta ttctcagtca gccatctttt
     3541 attcttcaac ggtcaatcct tcgactcgct ttgtaaatgc actcatttat gcccttttag
     3601 ctggagtagg agcttatcgt atcatgatgg gttcaacctt gaccgtcggt cgtttagtga
     3661 cttttttgaa ctatgttcag caatacacca agccctttaa cgatatttct tcagtgctag
     3721 ctgagttgca aagtgctctg gcttgcgtag agcgtatcta tggggtctta gatagccctg
     3781 aagtggctga aacaggtaag gaagtcttga ccagtgacca agttaaggga gctatttcct
     3841 ttaaacatgt ctcttttggc taccatcctg aaaaaatttt gattaaggag ttgtctatcg
     3901 atattccagc tggtagtaag gtagccatcg ttggtccgac aggtgctgga aaatcaactc
     3961 ttatcaatct ccttatgcgt ttttatccca ttagctcggg agatatcttg ctggatgggc
     4021 aatccattta tgattataca cgagtatcat tgagacagca gtttggtatg gtgcttcaag
     4081 aaacctggct cacacaaggg accattcatg ataatattgc ctttggcaat cctgaagtca
     4141 gtcgagagca agtaattgct gctgccaaag cagctaatgc agactttttc atccaacagt
     4201 tgccacaggg atacgatacc aagttggaaa atgctggaga atctctctct gtcggccaag
     4261 ctcagctctt gaccatagcc cgagtctttc tggctattcc aaagattctt atcttagacg
     4321 aggcaacttc ttccattgat acacggacag aagtgctggt acaggatgcc tttgcaaaac
     4381 tcatgaaggg ccgcacaagc ttcatcattg ctcaccgttt gtcaaccatt caggatgcgg
     4441 atttaattct tgtcttagta gatggtgata ttgttgaata tggtaaccat caagaactca
     4501 tggatagaaa gggtaagtat taccaaatgc aaaaagctgc ggcttttagt tctgaataag
     4561 ccattctctt ttgaaagttt atggacgaaa aaagttgcct tcgagtgact tttttgttac
     4621 aatagctaga aaaattgttc actgtaatac tcaatgaaaa ttaaagagca aactaggaag
     4681 ctagccgtag gttgctcaaa acactgtttt gaggttgcag atagaactga cgaagtcagt
     4741 aaccacacct acggcaaagt gaatctgaag tggtttgaag agagtacaac ttgtctttta
     4801 gaaaaggagc ctataatgaa agtctttcag catgtaaata tcgtgacttg tgatcaagat
     4861 ttccatgttt atcttgatgg aatcttagca gtcaaggatt ctcaaatcgt ctatgtcggt
     4921 caagataagc cagcgttttt agagcaagct gagcagatta tagactatca gggagcttgg
     4981 attatgcctg gtttggtcaa ttgtcacacc cattctgcaa tgacaggtct gagagggatc
     5041 cgagatgaca gcaatctcca tgaatggctc aatgactata tctggccagc agaatctgag
     5101 tttactcccg acatgactac caatgcggtc aaagaagccc taacagagat gctccagtca
     5161 ggaacaacaa cctttaacga tatgtataat cccaatggtg tggatatcca gcaaatttat
     5221 caggtggtga aaacttccaa gatgcgttgt tatttttctc cgactctctt ttcttcagag
     5281 acagaaacaa ctgctgagac tataagcaga actcgatcca tcatagatga aatcttaaaa
     5341 tataaaaatc caaatttcaa ggttatggta gcacctcatt ctccgtatag ctgcagtaga
     5401 gacttgctgg aagcgagttt ggaaatggca aaagagctaa atattccgct ccatgtccat
     5461 gtggcggaga ccaaggagga gtcaggaatt atcctcaaac gatacggcaa acgccccctt
     5521 gcttttcttg aagaactggg ttatttagat catccgtccg tatttgctca cggggtcgaa
     5581 ttaaacgaga gagaaattga acgcttggca tcttctcaag tggctatcgc ccacaatcct
     5641 atcagtaacc tcaaactggc atcaggaatt gctccaatta tccagctcca aaaagcggga
     5701 gtagcagtcg gaattgcgac tgactcggtt gcttccaata acaatctaga tatgtttgag
     5761 gaaggaagga ctgcagctct tcttcagaag atgaaaagtg gggatgccag ccagtttcca
     5821 atcgaaacag ctctcaaggt actgacaatc gaaggggcta aggtccttgg aatggaaaat
     5881 cagataggaa gtctggaagt cggcaagcaa gcagattttc tggtcattca accacaaggg
     5941 aaaattcatc tccaacctca ggaaaatatg ctgtctcacc tggtttatgc agttaaatct
     6001 agtgatgtag atgatgttta tatcgccgga gaacaggttg ttaagcaagg tcaagtcctg
     6061 acagtagaac tttaaaagaa aaatcacgaa aaattttaaa aaaagtttgc aaaaatcttg
     6121 cattcttttt ttgactatgc tatacttata tacggtttaa aaaaactgcc taagacagta
     6181 ggggagctcg actcataaat atcctaccga ggacaaaacg tatcatgtaa aaagaagcgt
     6241 attgtacttt cgtgtctagg tttgggcgcg tttttctttt tgaaaaattc cccaagcaaa
     6301 ataattacgg aggtgaacac actaatgagt gaagcaatta ttgctaaaaa agcggaacta
     6361 gttgacgtag tagctgaaaa aatgaaagct gctgcatcta tcgtcgttgt agacgctcgt
     6421 ggtttgacag ttgagcaaga tacagttctt cgtcgtgagc ttcgtggaag cgaagttgag
     6481 tataaagtta ttaaaaactc aatcttgcgt cgtgcagctg aaaaagctgg tcttgaagat
     6541 cttgcatctg tatttgttgg accatctgca gtagcatttt ctaatgaaga tgttatcgca
     6601 ccagcgaaaa tcttgaacga cttttctaaa aacgctgaag cacttgaaat taaaggtggt
     6661 gcaatcgaag gcgctgtcgc atctaaagaa gagattcttg cacttgcaac tcttccaaac
     6721 cgcgaaggac ttctttctat gctcctttct gtacttcaag cgccagtgcg caacgttgct
     6781 cttgcagtca aagcggttgc agaaagcaaa gaagacgcgg cttaatctta agctacacag
     6841 cgtagcctag ctacgaaaaa aactattata aaatttaaaa cttatttgga ggaaataaca
     6901 atggcattga acattgaaaa cattattgct gaaattaaag aagcttcaat ccttgaattg
     6961 aacgaccttg taaaagctat cgaagaagaa tttggtgtaa ctgcagctgc tcctgtagct
     7021 gttgctgcag ctgatgcagc tgatgctggt gctgctaaag attcattcga cgttgaattg
     7081 acatctgcag gcgacaaaaa agttggcgtt atcaaagttg tacgtgaaat tactggtctt
     7141 ggtcttaaag aagctaaaga acttgttgac ggtgcaccag cacttgttaa agaaggcgtt
     7201 gcaactgcag aagctgaaga aatcaaagct aaattggaag aagctggagc ttcagttact
     7261 cttaaataat agagtatcgc aatttaattg cggaatccct atttaccagt ctttgagagc
     7321 gataagcgat tgatagaaac tgataaattg atttggtttc ctgccaaaaa ttctttggca
     7381 ggatttttgt tttaataaac tttcgggggt agacactaga ttgtctaccc ctttttttgt
     7441 gtttcggagg taattatgca aaagaaagga cagtcatcac gtcaattcgt gaagagtcat
     7501 ctcatgacta tcatgggagt tgatattgta aaagcaactc agttagttga tgaaatggaa
     7561 caagtaggtt taatccgatt tgatgaattt ggaaatgttg aaattttagt cttggaggga
     7621 caatcatgaa gcgtattacc gctagtcaat atcagacatc agagcgttat tataagctcc
     7681 ccaaactttt atttgagagt gaacggtata agaatatgaa actagaagta aaggtggctt
     7741 attctatttt aaaagatcgt ttagaattat ctctcaatag tggttggata gatgaagaag
     7801 gggcggtcta tttagtattt tctaactcta aactgatgaa gcttttaggc tgttcaaagt
     7861 caaaattact ctccatcaag aaaactttac gtgagtatgg cctaattgat gaagtccaac
     7921 agtcttccag tgaaaaaggt cgtatggcta ataaaattta cttaggggaa ttagaacatg
     7981 agatacccct agtcttacat tcagacgggg ctagtgttaa aaacagatta gggcagtctc
     8041 aaaaacagac ggggccgttt ttaaattcag cccctagtga gactgaagaa agtgagactg
     8101 attctttatt tattgaggat gaggaggaga gggatactca acctatcttg aaaagaaaag
     8161 tagaaaaggt cacaaaatat gatcgagatt atatttgggg attggtacaa gatcaatttt
     8221 gacgagaggg gttttctgaa acagccagtg aaattgctat gactgatttt gagagaatct
     8281 atcagtatgc tcttgacaat gttcgctttg ttagacgagc ggaagtactt gctgaatttg
     8341 tgtttaacgg cctatattct gtttggaata accgtgttag aaaaggaggt ggttaaatgt
     8401 cgccaatcga gtggatatta gttatgctca ttttaatttc aagtggtgtg acactttgga
     8461 cattgatagt tgatcagaaa ggggtaatca agaaatgaga tttattgatt tattttcagg
     8521 tatcggtggt tttcgacttg gaatggaaag tgtcggacac gagtgtattg gattttgtga
     8581 gattgataaa tttgctagag aatcttataa gtccattttt caaacggaag gagaaataga
     8641 atatcatgac attaaagagg taacagatca tgactttaga caatttagag ggcaagtgga
     8701 catcatctgc gggggatttc cttgccaagc tttttcactt gcaggaagac gattgggatt
     8761 tgaagatact agaggaactt tgttctttga aattgctcgg gcggccaaac aaatccaacc
     8821 acgttttctt tttcttgaaa atgttaaagg cctactcaat cacgataagg gacggacgtt
     8881 caccacaatc cttaccacat ttgatgagtt ggggtttgat gttgagtggc aggtgcttaa
     8941 cagtaaggat tttggcgttc cccaaaacag agagagggtg tttattatcg gacattctag
     9001 aaagaaaggt accagactct tatttccttt cagacgagaa ggtcaagcaa ctaactctga
     9061 gactttgaaa gcactaggaa atttgaatcc atcaaaaagt ggcgtgagcg gtaaagtgta
     9121 ttattcagaa ggtcttgcgc caactttagt tcgtggaaaa ggagaaggat ttaaggttgc
     9181 tattccttgt atgacaccag atagattaga caaaagacaa aatggtagac gctttaagga
     9241 aaaccaagag ccgatgttta ctttaaatac tcaggatcgt catggcattg tcgttgttgg
     9301 agatttaccg actagtttta aggagacagg tcgtgtctat ggaagtgagg gcttatctcc
     9361 aacactgact acgatgcaag gaggagataa aatccccaaa atactaattc cagaaccaat
     9421 ccaatttcta aaagtacggg aagcaacgaa aaaaggatat gctcaagcag agattgggga
     9481 ttcaatcaat ttggaaagac caagttctca gtatcgtcgt ggtagagttg gcaaaggtat
     9541 agctaatacg ttaacaactg tggtagagtt ggcaaaggta tagctaatac gttaacaact
     9601 agtggtcaaa tgggagtagt agtggctagc tatgaaggag aagataaaca agtttaccaa
     9661 gtagctggtg ttttaataga tggacaattt taccgtttga gaatacgacg aatcactcct
     9721 aaagagtgtt ttcgattgca
//
LOCUS       DAVBOG010000069         8994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.070, whole genome shotgun sequence.
ACCESSION   DAVBOG010000069 DAVBOG010000000
VERSION     DAVBOG010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.070"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(358..1965)
                     /locus_tag="VQ865_001946"
     CDS             complement(358..1965)
                     /locus_tag="VQ865_001946"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HET3136241.1"
                     /translation="MSTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPY
                     INIDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRK
                     ERRGEYLGATVQVIPHITDALKEKIKRAALTTDSDVIITEVGGTVGDIESLPFLEALR
                     QMKADVGADNVMYIHTTLLPYLKAAGEMKTKPTQHSVKELRGLGIQPNMLVIRTEEPA
                     GQGIKNKLAQFCDVAPEAVIESLDVEHLYQIPLNLQAQGMDQIVCDHLKLDAPAADMT
                     EWSAMVDKVMNLKKQVKISLVGKYVELQDAYISVVEALKHSGYVNDVEVKINWVNAND
                     VTAENVAELLSDADGIIVPGGFGQRGTEGKIQAIRYARENDVPMLGVCLGMQLTCIEF
                     ARHVLGLEGANSAELAPETKYPIIDIMRDQIDIEDMGGTLRLGLYPSKLKRGSKAAAA
                     YHNQEVVQRRHRHRYEFNNAFREQFEAAGFVFSGVSPDNRLVEIVEIPENKFFVACQY
                     HPELSSRPNRPEELYTAFVTAAVENSN"
     gene            complement(2355..2942)
                     /locus_tag="VQ865_001947"
     CDS             complement(2355..2942)
                     /locus_tag="VQ865_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000418402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HET3136242.1"
                     /translation="MELEVFAGQEKSELSMIEVARAILELRGRDHEMHFSDLVNEIQN
                     YLGTSNSDIREALPLFYTELNFDGSFISLGDNKWGLRSWYGVDEIDEEIIALEENDDD
                     EVAPKAKKKRVNAFMDGDSDAIDYNADDPEDEDAYEADPALSYDDENPDDEKNEVEAY
                     DAEINEIAPDDLGEDVDLNEDDDEFSDDDAETSEE"
     gene            complement(3070..3519)
                     /locus_tag="VQ865_001948"
     CDS             complement(3070..3519)
                     /locus_tag="VQ865_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000333655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136243.1"
                     /translation="MCFVPYYKVNYCEEAFAWYQDVNLVYLVDGVKLPYSQATLEAMY
                     SYLDRHGELFWIEVKEKGEWFPIGDITLSQDNLPIVIGNSAYQHRGLGKKILSALIEL
                     ARVKGWKELRVKEIYTYNHASRRCFKSLGFVENGATEKGRSFILELV"
     gene            complement(3524..3913)
                     /locus_tag="VQ865_001949"
     CDS             complement(3524..3913)
                     /locus_tag="VQ865_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partitioning protein ParB"
                     /protein_id="HET3136244.1"
                     /translation="MKVNIADLHPTQLYLSEKKLQDIQMLYQSAETIQVDPISILAFG
                     DCLLITDGHHRAYQALLAGRDTISAEWDRDGGDELYHLYAQACEERKIYSVFDLEDRI
                     LAQDGYEAKWYNWCDGFNQAATLLLKR"
     gene            complement(3941..4567)
                     /locus_tag="VQ865_001950"
     CDS             complement(3941..4567)
                     /locus_tag="VQ865_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001853067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HET3136245.1"
                     /translation="MKGSFALLLFVILGYMVKFYPEMLVNFDQSIQTAIRGDLPDYLT
                     ILFRSLTRLIDIPVIITWVVITAFVFYRKRWKIESFFMLGNLALAGLLIVTFKNIYQR
                     PRPAILHLVEEKGFSFPSGHSLAVTLMVGTLIVILSQRIKDPVWRKIVQIVLGLYLVS
                     VLVSRVYLGVHYPSDVLASLCVGLGVLFIEFPFYDKLRFQWRFKGKQK"
     gene            complement(4581..5144)
                     /locus_tag="VQ865_001951"
     CDS             complement(4581..5144)
                     /locus_tag="VQ865_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HET3136246.1"
                     /translation="MTNTRRLSTIAILSAISFVLMYFDFPLLPAASFLKIEFSILPVL
                     VGLVVMDLPAALGVLLLRSLLKLLLNSQGVNTYIGLPMNIVALGVFVIVFALIWKKER
                     TTLRFLLGSLAGTVGLTLAMLVLNYVYAVPLYAKFANFDIGKILGLSNYLMTMVLPFN
                     LIEGVIFSVSFWLLYVLLKPTLKHYER"
     regulatory      complement(5309..5543)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(5597..6100)
                     /locus_tag="VQ865_001952"
     CDS             complement(5597..6100)
                     /locus_tag="VQ865_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (cytidine(34)-2'-O)-methyltransferase"
                     /protein_id="HET3136247.1"
                     /translation="MTNHIVLFEPQIPQNTGNIARTCAATNSPLHIIKPMGFPIDDRK
                     MKRAGLDYWDKLEIYFYESLEDFISQMKGKLYLISKFAEKVYSEVDLSTDEDHYFLFG
                     REDKGLPEDFMREHPEKALRIPMNDEHVRSLNVSNTVCMIVYEALRQQNFAGLELVHT
                     YEVDKLK"
     gene            complement(6293..7123)
                     /locus_tag="VQ865_001953"
     CDS             complement(6293..7123)
                     /locus_tag="VQ865_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004260602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HET3136248.1"
                     /translation="MQAKLIGYQHRDTVIHRLSGAGKLLFFILVSLAAMISYDTRMLL
                     LIAIFSVFLLYLSEIRFKDVSFVAVFATVFAVLNVLMVYLFSPEYGVGLYGERSVIWQ
                     GIGVYTLTSQELFYLLNLAIKYLCTIPLAIIFLMTTHPSQFASSLNQIGVPYKIAYSV
                     SLTLRYIPDLQEEFFTIKMSQEARGMELSKKASLMQRIKGNLLIITPLIFSSLERIDT
                     IATAMELRRFGKEKKRTWYSYQALKKGDYITLLLATLFLVVSLLLILQNQGRFYNPWK
                     "
     gene            complement(7108..8790)
                     /locus_tag="VQ865_001954"
     CDS             complement(7108..8790)
                     /locus_tag="VQ865_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136249.1"
                     /translation="MKEAIIEWKDFSFRYETQQEPTLQGIDLTIYKGEKVLIVGPSGS
                     GKSTLGQCLNGIIPNIYKGQTYGEFLIKGQVAFDMSIYDKSHLVSTVLQDTDGQFIGL
                     SVAEDLAFALENDVTALDEMKGRVYKWAEKLDLLPLLDQRPQDLSGGQKQRVSLAGVL
                     IDESPILLFDEPLANLDPKSGQDIIELIDQIHKEEGTTTLIIEHRLEDVLHRPVDRIV
                     LINDGRILFNGSPDQLLATDLLTQNGIREPLYLTTLRQLGVDLVKEEQLADLDNLSIS
                     KGQVQLQTELVKETSELQSLFRLEEVSFSYDDRPILKSLHLDIKKGEKIAIVGKNGAG
                     KSTLAKAISSFIQTEGRYLWEKQDIKGDSVAERAERVGYVLQNPNQMISTNMIFDEVA
                     LGLRLRGVDEKEIETRVYETLKICGLYEFRNWPISALSFGQKKRVTIASILVLGAEII
                     LLDEPTAGQDQKNYTEIMEFLEELHQKGHTIVMITHDMQLMLDYSDRVLVMVDGELIA
                     DTVPASLLSDPELLVKANLKETSIFNLAKKLDVDPLDLTAFYKERREGCKLN"
BASE COUNT         2722 a         2058 c         1637 g         2577 t
ORIGIN      
        1 tggattaaat taaaaaagta taatgtattg aatctataac agtacatctt gactgctaaa
       61 atatttctat aaattaattt gacttttctg atagagatgt tcacatctta tttcaattca
      121 ctatacaatc cagttcctaa aactttgcta gaaattgatt tggctttccg aattaatttg
      181 ttcaaatttt atttcatttc aatatactga taaatccatt cactagcaca gggcaagagg
      241 gagtcgctat tgatttcaac ggtagcaggt acatacagag gactcctacc tcagatatac
      301 tgcaatatca tcgtatgcaa aaaacctctg agatttttct caaaggttct gattttgcta
      361 attgctgttc tcaaccgctg cagtaacaaa ggcagtgtag agttcttctg gtcggtttgg
      421 acggcttgac agttcagggt gatactgaca agctacaaag aatttatttt caggaatttc
      481 cacgatttct accaaacgat tgtctggaga aactcctgaa aagacaaaac ctgctgcctc
      541 aaactgctca cggaaggcat tattaaactc ataacggtga cggtgacggc gttgcaccac
      601 ttcttgattg tgataagcag cagcagcctt agagccacgt ttcaacttag acggataaag
      661 tcccaaacga agggttccac ccatatcctc aatatcaatc tgatcacgca tgatatcaat
      721 gatagggtat tttgtttctg gtgcaagctc tgcagaattg gcaccttcaa gacctaaaac
      781 gtgacgagca aactcgatac atgtcaactg cattcccaag cagactccca acattggaac
      841 atcattttca cgcgcatagc ggatggcttg gattttccct tctgtaccac gttgaccaaa
      901 accacctggt acgatgatcc cgtccgcatc agacaagagt tctgctacat tctctgctgt
      961 cacatcattg gcattgaccc aattgatttt aacttctaca tcattgacat agccagagtg
     1021 tttcaaggct tcgaccactg agatataggc atcttgcaac tccacatact taccaacaag
     1081 ggaaatctta acttgtttct tgaggttcat gaccttgtcc accatggctg accattctgt
     1141 catatccgct gctggtgcgt ctaatttcaa atgatcacaa acaatttggt ccatcccttg
     1201 tgcctgcaag ttcagtggaa tttggtaaag gtgttcaaca tccaacgatt cgataacggc
     1261 ttctggtgcc acatcacaga actgggccag tttattttta attccttgac cagctggctc
     1321 ttctgtacga ataaccaaca tatttggttg gattcccaag ccacgcaatt ctttgacaga
     1381 gtgttgggtt ggtttggttt tcatttcacc agcagccttg aggtaaggaa gcaaggttgt
     1441 atggatatac atgacattat ccgcacccac atctgccttc atctgacgaa gagcctctag
     1501 gaatggcaag gactcgatat ctcctactgt tccaccaacc tctgtgataa tgacatcaga
     1561 gtcggtcgtt agagcggcac gcttgatttt ttctttcaaa gcatctgtga tatgaggaat
     1621 gacttgaaca gttgccccaa ggtattctcc acggcgttct ttacgaagaa cttcactgta
     1681 aattttccca gttgtcacgt tggaatattt gttgagattg atatcgatga aacgttcata
     1741 gtgacccaag tccaaatctg tctcagctcc gtcatctgtc acaaaaactt ccccgtgctg
     1801 gtaaggactc atggttcccg gatcaatatt gatataaggg tcaaactttt gaatggttac
     1861 tttgagacca cgatttttca agagacggcc tagactcgct gccacaatcc ctttcccaat
     1921 ggacgatacc acaccaccag ttacaaaaat atatttcgta gacatagatt cctctttcta
     1981 aaatgctcaa ggtcttgtta actacgaggg gatatagaaa acaagaccct actaataaga
     2041 ataatctggg acgactgcac cagattcaca actaatactc ttcgaaaatc tcttcaaacc
     2101 gcgtcaacgt cgccttgccg tagatatgtg ttcctgactt tgtcagtctt atctacaacc
     2161 tcaaaacagt gttttgagca gcctacggct agtttcctag cttgctcttt gattttcatt
     2221 gagtataaaa tacaagaaga taacttcttg aaaaaacaaa aatagctccc taagaactag
     2281 ggagccccga cctctaaaag aggtgcccaa acaatatgat acctaaaaat aggataattg
     2341 tcaatagcta actcttattc ctcgctggtt tcagcgtcgt catctgaaaa ctcgtcgtcg
     2401 tcttcgttga gatccacatc ttctcccaag tcatctggag cgatttcgtt gatttctgca
     2461 tcataagctt ccacttcatt tttttcatca tctggatttt catcatcgta tgaaagagct
     2521 ggatctgctt cgtatgcatc ttcgtcttct ggatcatctg cattgtagtc aatggcatct
     2581 gaatcaccat ccataaaggc attgacacgt tttttcttag cttttggtgc tacttcatcg
     2641 tcgtcatttt cttcaagagc gatgatttct tcgtcgattt cgtccacacc ataccatgaa
     2701 cgaagacccc atttgttgtc cccaagtgag atgaagctac cgtcaaagtt caactctgtg
     2761 tagaacaaag gcaaagcttc gcggatatcg ctgtttgatg ttccaaggta gttttgaatt
     2821 tcgtttacaa gatcgctaaa atgcatctca tgatcgcgac cacgaagttc caagatagca
     2881 cgcgctacct caatcataga tagttcactt ttttcttgcc cagcaaatac ttctaattcc
     2941 aaagcgtttc tcctcattta tactactatc gccagagcga acagactctg acctcatttt
     3001 atcatttact ctttatttta cgataatttt gcggaatagt caaaggttaa gggggagaaa
     3061 gtggcaggat tagactaatt ccaatataaa actccttcct ttttctgttg ctccattttc
     3121 cacaaatcca agcgacttga aacacctcct agaagcatga ttgtaggtgt agatttcctt
     3181 gactctcaat tctttccatc cttttactcg agccaattca atcaaagcac ttagaatctt
     3241 ttttccaagt cctcgatgtt ggtaagcgga attcccaatc acaatgggga gattatcctg
     3301 agatagtgta atatccccaa ttggaaacca ttctcccttc tccttgactt caatccaaaa
     3361 aagctcacca tgccgatcca aataggaata catggcttcc aaggtcgctt gactgtaagg
     3421 aagcttcacc ccatctacga ggtaaaccaa gttcacatcc tgataccaag caaaagcttc
     3481 ctcacaataa ttgaccttat aataaggaac aaaacacaat gcactacctt ttcaacaaaa
     3541 gagttgctgc ttgattaaaa ccatcacacc agttatacca ttttgcttca tacccatctt
     3601 gagctaggat acgatcttct aaatcaaaaa cagagtaaat ctttctttcc tcgcaagctt
     3661 gcgcatagag atgatatagt tcatcaccac catctctatc ccactcagca gaaatcgtat
     3721 cccgacctgc caataaagcc tgataagccc tgtgatgccc atctgtaatc agcaaacaat
     3781 ctccaaaggc aagaatactg attggatcga cttggattgt ttctgccgac tggtaaagca
     3841 tctgaatatc ttgcaacttc ttttctgata aatatagttg agtcggatga agatctgcta
     3901 tattgacttt catttctttc tcctcaaggg aattcgatac tcacttctgt ttgcctttaa
     3961 atcgccattg gaagcggagc ttgtcataga agggaaactc gataaacagg actcccaagc
     4021 ccacacagag actggcaagg acgtctgatg ggtaatgaac tcccagatag actcttgata
     4081 ccagcacact gactaggtag aggccaagga cgatttgtac gatttttctc cagactggat
     4141 ctttaatccg ctgactaaga ataacaatca aagtacctac catcaaggtt acagccagag
     4201 aatgcccact tgggaaggaa aatcccttct cctccaccag atgtaagata gctggtcgtg
     4261 ggcgctggta gatattttta aaggtcacga ttaaaagacc tgccaaagcc agatttccca
     4321 gcatgaagaa actttctatc ttccatcgct tacgataaaa gacaaaagct gtaatgacaa
     4381 cccaagtgat aatcactggg atatcaatca gacgtgtgag ggatcgaaaa agaatagtca
     4441 aataatctgg taagtctcct cgaatggcag tctgaatcga ttggtcaaaa ttgaccaaca
     4501 tttcagggta aaatttgacc atatagccaa gaataacgaa aagtaaaagg gcaaaactgc
     4561 ccttcattaa aaatgtttgt ttatctttca tagtgtttta aggttggttt caaaaggacg
     4621 tacaacaacc agaatgaaac ggaaaagatt acaccctcaa tcaagttaaa aggtaatacc
     4681 atggtcatta ggtagttgga aagtcccaaa atttttccaa tatcaaagtt agcaaactta
     4741 gcgtacaaag gaacagcata aacatagttg agaaccaaca tggccaaggt taaaccaaca
     4801 gttccagcta gagagcctag taggaaacga agggttgtcc gttccttttt ccaaatcaaa
     4861 gcaaatacga tgacaaaaac tcccaaagct acgatattca tcggcaaacc aatgtaagta
     4921 ttcactcctt ggctgttaag aagcaatttc aatagtgagc gaagcaagag cactcctaga
     4981 gcagcaggca aatccatgac caccagaccc acaaggactg gcaagatact aaattcgatc
     5041 ttgaggaaag atgccgctgg taaaagcgga aagtcaaagt acatcagcac aaatgagatg
     5101 gctgataaaa ttgcaatggt cgaaagtcga cgtgtgtttg tcataacagg ttcctccaat
     5161 tttctataaa atcagaagaa gttggaaagg attcctctat ctattctcac tttttatatc
     5221 ccaaaagttc cctcttactc tattaaagaa aaacaaagca agtggttaca atccggctat
     5281 aaatctatca aaacagacaa agctattctt tcgtcttctc ccatccagac tatactgtcg
     5341 gttgtggaat ctcaccacat cagcttgcgc tcgcggactt ctttaaagag aaggaaatag
     5401 agatttttct tttagactag gcgacaagct gtaggcataa cttctggtta ggcaaagctt
     5461 gtcaacaaag tataaaagga aaagatcatt tcctagttaa agtcaccgcc ggtcgggaat
     5521 cacaccctgc cctgaagact cttttatcat aacaaaaaac gcttgcaagc gcaagcattt
     5581 tgttcatttt cattttttat ttcaatttat ccacttcata ggtatggacg agctcaagac
     5641 ctgcaaagtt ctgctggcga agagcctcat agacaatcat gcagacggta ttagacacat
     5701 tgagactgcg gacatgttca tcattcatgg gaatacggag agccttctca ggatgttctc
     5761 gcataaaatc ttcaggtaag cccttgtctt cacgtccaaa gagaaaataa tggtcctcgt
     5821 cagtcgataa atccacctca gaatagactt tttccgcgaa tttcgaaatc agatagagtt
     5881 ttcccttcat ctgagatatg aaatcttcca aactctcgta aaaataaatc tctagcttat
     5941 cccagtaatc caatccagcc cgcttcatct tgcggtcatc aataggaaag cccataggct
     6001 tgatgatgtg gaggggagaa ttggtcgcag cgcaagtacg cgcgatattg cccgtatttt
     6061 gtggaatttg aggttcaaat aatacaatgt gatttgtcat gacttgcttc ctttcaccat
     6121 tgcaaaaaaa tagccacact gcccggagtc aagctcagca aacagcgtgg ttaaggcatc
     6181 gttaacttac ctcacaacag gtttgaagta aatcagcgaa actactttct tagtataaca
     6241 ctttcagaat cattgtcaat agaaatgact tgattttttc aattttttca agctatttcc
     6301 aagggttgta aaatcgtccc tgattctgca agataagtag taaactaact actaaaaaca
     6361 aggttgccaa gagcaaggta atatagtctc cttttttcaa ggcctgataa ctataccatg
     6421 tgcgtttttt ctctttccca aagcggcgaa gctccatggc agtcgcaatg gtatcaatgc
     6481 gttctagcga gctaaaaatc aagggcgtaa taatgagcag attgcctttg attcgttgca
     6541 taagagaagc tttcttggat aattccatcc cacgcgcctc ctgagacatc ttgatagtaa
     6601 agaattcttc ctgcaaatct ggaatatagc gcaaggtcag gctgacagaa taagcaatct
     6661 tatagggcac accaatttga tttaaactgg aagcaaactg actaggatgg gttgtcatca
     6721 aaaagataat agccagagga atggtgcaaa gatacttaat ggccaaattt agcagataaa
     6781 agagctcctg gctggttaga gtgtagacac cgattccctg ccaaatcaca cttctctctc
     6841 cataaagtcc aaccccatac tcgggagaaa agagatagac catcaaaacg tttaaaacgg
     6901 caaataccgt cgcaaaaacg gctacaaagg aaacatcttt aaagcgaatt tctgataaat
     6961 agaggagaaa gactgaaaag atggcaatca gcaagagcat tctggtatca tagctaatca
     7021 tggccgccaa tgataccaga atgaaaaaga gaagtttccc agctcctgac aagcgatgaa
     7081 tcacagtatc tctatgctgg taaccgatta atttagcttg catccctctc tcctttcttt
     7141 gtaaaatgcc gttaaatcca gtggatccac atctagtttc ttagccaagt taaagatgga
     7201 ggtttctttt agattggctt ttactaacag ctcaggatcg ctcaacagac tggctggaac
     7261 agtatcggca atcaattctc catccaccat gacaaggacc cggtctgaat aatccagcat
     7321 caattgcata tcatgggtaa tcatgacaat ggtatgccct ttttgatgta actcttcgag
     7381 aaattccata atctcagtat agttcttctg atcttgacct gcagtcggtt catctaggag
     7441 aataatttca gctcctaaga ccaaaattga agcaatggtg acacgttttt tctgaccaaa
     7501 tgacagggca gaaataggcc aattacggaa ttcataaagt ccacagattt tcaaggtttc
     7561 atagactctc gtttcaattt ccttctcatc cacacctcgc aaacggagcc ctagagccac
     7621 ctcatcaaaa atcatattgg ttgaaatcat ttgattagga ttttgtagca catatcctac
     7681 tcgttccgcc cgctctgcaa cagaatcgcc ttttatatcc tgtttttccc aaagatagcg
     7741 tccttccgtc tgaataaagc tacttatagc cttggctaga gttgatttcc ctgctccatt
     7801 ttttccgaca atagcaatct tttcaccctt tttaatatct aaatgtaggg attttaaaat
     7861 cggtctatca tcataagaaa aagatacttc ctctagtcta aagagtgact gcaattctga
     7921 ggtttctttt accagttccg tctgtaactg gacttgccct tttgagatag acaagttatc
     7981 cagatctgct aattgttctt ccttgactaa gtccacacct aattgacgga gagtggttag
     8041 ataaaggggt tctcgaattc cattttgagt caataaatca gtcgcaagca actggtcagg
     8101 gctcccatta aaaaggatac gaccatcgtt tatcaagaca atccgatcca cagggcgatg
     8161 cagaacgtcc tccaaacggt gctcgataat cagagtcgtc gtcccctctt ccttatgaat
     8221 ctggtcaatc aattcgataa tatcctgacc tgacttggga tctagattgg cgagtggctc
     8281 atcaaacaag agaatcggac tttcatcaat caagacacca gccagactga ctcgctgctt
     8341 ttgtccacct gacaaatcct gaggacgctg atccagtaaa ggaagaaggt ccagcttttc
     8401 agcccattta taaacacgac ctttcatctc atctagggct gtcacatcat tttccagagc
     8461 aaacgccaaa tcttctgcca cagacaagcc aataaactgc ccatctgtat cctgcaaaac
     8521 tgtgctaacc agatgagact tatcatagat gctcatatca aaggctactt gaccctttat
     8581 caaaaattct ccatatgtct gacccttgta aatattggga ataatcccat tcaaacactg
     8641 acccaaggta gatttacctg acccagatgg tccaacaatt aagactttct ctcccttgta
     8701 aatggtcaag tctatccctt gcaaggtcgg ttcttgttgt gtttcatacc ggaaagagaa
     8761 atccttccac tcaattatag cttctttcat cttactctct tcattcgctt cttagacttc
     8821 tattttatca taaatcaagc ccttcttgca gtctcttctc ttaaaatctt agcgccaaaa
     8881 agattcctat cctagcttac ttgcctaact aatctataaa catcgaaaaa gactagttgc
     8941 ccagccttcc ccatcatttt atactcttcg aaaatctctt caaaccacgt cagc
//
LOCUS       DAVBOG010000070         8327 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.071, whole genome shotgun sequence.
ACCESSION   DAVBOG010000070 DAVBOG010000000
VERSION     DAVBOG010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8327)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8327)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8327
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.071"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(549..857)
                     /locus_tag="VQ865_001955"
     CDS             complement(549..857)
                     /locus_tag="VQ865_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000134125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HET3136250.1"
                     /translation="MTEEMEYICFQLIANSGAAKSSFIEAIQLAKAGNLKEAKIKVEE
                     AEDSLVEAHKIHSNLIQKEATGEKIGFSLLFMHAEDQMASTEIIQLLSKEFIDLYQNK
                     "
     gene            complement(854..1162)
                     /locus_tag="VQ865_001956"
     CDS             complement(854..1162)
                     /locus_tag="VQ865_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3136251.1"
                     /translation="MKQILLVCNAGMSTSMLVKKMQQSATERGIEISIQAKSMTEAKK
                     NIHEADVILIGPQIRYELLAVKEIAGNTPVDTIDMRDYGMMNGAKVLEQALAWIGEIR
                     "
     gene            complement(1167..2462)
                     /locus_tag="VQ865_001957"
     CDS             complement(1167..2462)
                     /locus_tag="VQ865_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HET3136252.1"
                     /translation="MKNSKFIDQFATFAGKLGNQIHLKTLRDAFVTVMPLYILAGLIV
                     LLNNTVFKWIFQGDTLTKFQYWGITIANGTLSISGMIIAVMVGYFLAKNRDFENPLAA
                     SMLSLVSLIVMMPNTVSVVPDGAKDAVNISGVLSFNNTGTGAMFAGVIVAIIATELFI
                     ELSNVKALQMNLGENIPPAVSRSFSVLLPVMTVISLFGVVSALLFNITGMNLISIITI
                     FIQEPIRHIGTSLIGVIIIYSLGNMLWLFGIHQAVIYSAILEPLLLINITENITAANN
                     GQAIPHIINLSQIQTFALMGGSGSTLCLLIATFLVSRNAVSKNVAKLSFGPGIFNINE
                     PVLFGYPIVYNISLAIPFITVPVLGILISYLATVTGFMSPAFIQVPWTTPVFLNAWLA
                     TAGDVRAVLVQFIIFALGVLLYIPFIKVNDKVVEQEMEG"
     gene            complement(2480..3889)
                     /locus_tag="VQ865_001958"
     CDS             complement(2480..3889)
                     /locus_tag="VQ865_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000728302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3136253.1"
                     /translation="MKKKLVFPNLFWWGAASSGPQTEGQYGKVHENVMDYWFKTHPED
                     FFDNVGPLVASNFFHTYTEDFHLMKEIGVNSFRTSIQWSRLIKNLETGEPDPKGIAFY
                     NAIIEEAKKNQMDLVMNLHHFDLPVELLQKYGGWESKHVVELFVKFAKTAFTCFGDKV
                     HYWTTFNEPMVIPEAGYLYAFHYPNLKGKGKEAVQVIYNLNLASAKVIQLYRSLGLDG
                     KIGIILNLTPAYPRSNSPEDLEASRFTEDFFNKVFLNPAVKGTFPERLVKQLERDGVL
                     WSHTEKELQLMKSNTVDFLGVNYYHPKRVQAQANPEEYQTPWMPDQYFKEYEWPERRM
                     NPYRGWEIFPKAIYDIAMIVKEEYDNIPWFISENGMGVENEARFIDENGVIDDVYRIE
                     FYEEHLRWLHKAIEEGSHCFGYHAWTAFDCWSWNNAYKNRYGFISVDLETQKRTIKSS
                     GRWYRKVSDNNGFEVEIEE"
     gene            4047..4775
                     /locus_tag="VQ865_001959"
     CDS             4047..4775
                     /locus_tag="VQ865_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000105270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HET3136254.1"
                     /translation="MSTKYLFIYNEIREKILCNKYTMNEQLPDEMTLAKQFACSRMTI
                     KKALDLLVSEGLIFRKRGQGTFVLSRGSSKRKLIVPERDIRGLTKISEDAHSTIDSRI
                     IHFKLEFANEFLAEKLQVALQSPVYNIYRLRIIDGKPYVLEQTYMSTDVIPGITEDIL
                     QKSIYNYIEGKLGLHIASATKILRASSSSENEQHYLQLLPTEPVFEVEQVAYLDNGTP
                     FEYSISRHRYDLFEFNSFALRHSS"
     gene            5234..5428
                     /locus_tag="VQ865_001960"
     CDS             5234..5428
                     /locus_tag="VQ865_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001818644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HET3136255.1"
                     /translation="MKGKEYENRTVSFAISSKGEKMKVENISYRVDHRILFDNISFDT
                     SSSGVTLITGKNGTGKSTLL"
     gene            complement(5793..7103)
                     /locus_tag="VQ865_001961"
     CDS             complement(5793..7103)
                     /locus_tag="VQ865_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HET3136256.1"
                     /translation="MIHLIMISAIALAIGIGYRTKINIGLLAIAFSYLIATTLMGLSP
                     KELLHFWPTSLFFTIFSVSLFYNVATTNGTLDVLAQHILYRTRTHPNALYMILYLMAT
                     LLSALGAGFFTTMAVCCPLAITLCQKADKHPLIGAQAVNWGASGGANLITSSSGIVFQ
                     GLFKQMGWEEQAFSLGNHIFIVSIIYPLIVLLLLSCYSHYSKGRTNSSLTIDQPPLLS
                     KVQRQTTLLMISSMVLVWLFPLLHLIFPNIAWIATYQKTFDIGFVSILMVCLALRLKL
                     GKQEAILAKVPWATIIMLCGMSLLMSLAVKSGLVTLIGHLMTTTIPHFWLPLFFCVIA
                     GVMSLFSSTLSVVAPALFPIIAIISAQNPQIDIHLLTTATVIGALSTNISPFSSAGSL
                     IQLSLPNIEERGLAFKKQIILGVPISLSLGLLTTWILILLASLS"
     gene            7340..8212
                     /locus_tag="VQ865_001962"
     CDS             7340..8212
                     /locus_tag="VQ865_001962"
                     /EC_number="2.4.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HET3136257.1"
                     /translation="MSIISTDLTPFQIDDTLKAALREDVHSEDYSTNAIFDHHGQAKV
                     SLFAKEAGVLAGLTVFQRVFTLFDAEVTFQNPHQFKDGDRLTSGDLVLEIIGSVRSLL
                     TCERVALNFLQHLSGIASMTAAYVEALGDDCIKVFDTRKTTPNLRLFEKYAVRVGGGY
                     NHRFNLSDAILLKDNHIAAVGSVQKAIAQARAYAPFVKMVEVEVESLAAAEEAAAAGA
                     DIIMLDNMSLEQIEQAITLIAGRSRIECSGNIDMTTISRFRGLAIDYVSSGSLTHSAK
                     SLDFSMKGLTYLDV"
BASE COUNT         2589 a         1457 c         1583 g         2698 t
ORIGIN      
        1 gatagagttg ttcacatctt atttcaattc actatagttt aatttaagag tagtatttac
       61 taaggcccaa ttaaaatcaa agagcaaacg agaaaacgat gacaaggtgt gttgcttttt
      121 gatttctaaa gagtataatg atagatctct ataaaataag tgcgaaggaa atgagctttt
      181 ataatccttt cgttttaaaa tactatctca gatattctta tatcgacaag aagtttttga
      241 gtcattccct catcatacat attaaataaa tagtggctca ttcaattttt cactagaata
      301 ataagctagt atagtaaact gaaataagat ataaacaaat aaattggagc ttaacatcta
      361 tttccagcaa ttttttagaa attgcagtgg actattctag attcaataca ttataaaaac
      421 tagagtaaaa gaaaaggatt ggatcttgtg taatgcagga tccaatcctt tcaatcattt
      481 tgtccaactt ttggaggttc ctacaatgta gccgtcatta ataaagacag atgggaacga
      541 cagtgttcct atttattttg atagagatcg atgaattctt tagatagcaa ctgaataatc
      601 tctgttgaag ccatttggtc ttctgcatgc ataaatagca aggagaatcc tattttttct
      661 ccagtagctt ctttttgtat gagattagag tgaatcttgt gcgcttctac taaggagtct
      721 tccgcttctt caactttaat tttcgcttct tttaaatttc ccgccttagc tagttggatg
      781 gcttcaataa aggatgattt ggctgctcca ctattggcaa tgagctgaaa acagatatat
      841 tccatttctt ctgtcatctt atttctccta tccatgcaag tgcttgttcc agaacttttg
      901 ctccattcat cattccgtaa tcccgcatat caatggtatc tacaggggta tttcctgcaa
      961 tttctttcac agcaagtaac tcataacgaa tttgtggccc aattagaatg acatctgctt
     1021 catggatatt ctttttagct tctgtcattg attttgcttg gatagaaatt tcaatcccac
     1081 gttcagtcgc actttgttgc atttttttaa caagcatact tgtcgacatt cccgcattac
     1141 atactaataa aatttgtttc ataatcttaa ccttccattt cttgttcaac aactttgtca
     1201 ttaactttga taaatggaat gtatagaaga actccaagtg caaagatgat gaattgaact
     1261 agaactgctc tcacgtcccc tgctgttgct aaccatgcat ttaagaatac tggtgtagtc
     1321 caaggaactt gtataaatgc aggactcatg aatcctgtaa ctgttgctaa gtagctgatt
     1381 aaaataccaa ggactggaac tgtgataaat ggaatagcta atgaaatgtt ataaacgatt
     1441 gggtaaccga ataatactgg ttcattgata ttgaagatac caggtccaaa agataattta
     1501 gccacgtttt tagaaacagc attgcgactc actaagaatg ttgctattaa taaacataat
     1561 gtagatccac taccacccat taaagcgaat gtttgtattt gtgataagtt gatgatgtgt
     1621 ggaatggctt gtccattatt tgctgcagtg atgttttcag taatgttaat taatagtaat
     1681 ggttctagga tggcactgta aataactgct tggtgaatac caaatagcca taacatattt
     1741 cctaaagagt aaataataat gaccccgatt aagcttgtac caatatgacg aattggttct
     1801 tgaataaaga ttgtaatgat tgagattaag ttcattccag ttatattgaa taataatgct
     1861 gaaacaaccc caaataagga gatgacggtc atgactggaa gtaatacgct aaatgatcta
     1921 ctaacagctg gtggaatatt ttcaccaagg ttcatttgta aagctttaac gtttgataat
     1981 tcaatgaata attctgttgc aataatcgct acgataaccc cggcgaacat tgcgcctgta
     2041 cctgtgttgt tgaatgaaag aacacctgaa atgtttaccg catcttttgc tccgtcagga
     2101 actacagaaa ctgtatttgg catcatcaca attaaagaaa ctaatgatag cattgatgct
     2161 gctaacgggt tttcgaaatc tctgttttta gctaagaaat aaccaaccat tacagcaata
     2221 atcatacctg aaatacttaa agtaccgttt gcaattgtta ttccccaata ttggaatttt
     2281 gttaatgtat ccccttggaa aatccactta aataccgtgt tgttcaaaag aacgattaaa
     2341 cctgccaaaa tatataatgg cattactgtt acgaatgcat ctcttagggt ttttaaatga
     2401 atttggttcc ctagtttacc agcaaaggtg gcaaattgat ctataaattt tgagtttttc
     2461 atctgaatat ctcctctctt tactcctcaa tttctacttc aaaaccgtta ttgtcactta
     2521 ctttgcgata ccatcttcct gagctcttga tggttctctt ttgcgtttct aaatcaacgg
     2581 agataaatcc gtaacgattc ttatatgcat tattccaaga ccagcaatca aatgcggtcc
     2641 aagcgtggta tccaaaacag tgacttccct cttcaatggc tttatgtagc catcttaaat
     2701 gttcttcata aaattcaata cgatacacgt catcgataac tccattttca tcgataaacc
     2761 gtgcttcgtt ttcaacaccc attccgtttt cactgataaa ccatggaata ttatcatatt
     2821 cttccttcac aatcatagca atatcataaa tggctttcgg aaaaatttcc caaccacgat
     2881 atggattcat gcgacgctcc ggccattcat actctttgaa gtattggtct ggcatccagg
     2941 gcgtctgata ttcctcagga tttgcttgtg cttgaacacg ttttggatgg tagtagttta
     3001 ctccaagaaa atcaaccgta tttgatttca tcagttgaag ctctttttcg gtatgactcc
     3061 ataacacgcc atctctctct agctgtttta ccaatctttc tgggaaagtt cctttaacag
     3121 ctggattcaa gaagactttg ttaaagaagt cttctgtaaa tcgacttgct tctaagtctt
     3181 ctggagaatt acttcttgga taagcaggtg tcaagtttaa aataatccca atctttccat
     3241 caagtcctaa tgagcgatat agttgaatca cttttgcact agcaaggttt agattataga
     3301 tgacttgtac ggcctctttt ccctttcctt ttagatttgg ataatggaaa gcatataagt
     3361 atcctgcttc tggaatgacc attggctcat tgaaagttgt ccagtaatga accttatctc
     3421 caaagcatgt gaaagcagtc ttggcaaact tcacgaataa ctccactaca tgtttgcttt
     3481 cccaaccacc gtatttttga agaagttcca ctggtaaatc aaaatgatgt aaattcatca
     3541 caagatccat ctggttcttt ttagcttctt caatgatggc attgtagaaa gcaatacctt
     3601 ttggatcagg ctcacctgtc tctaaattct tgatgagtcg actccattgg atggaagtgc
     3661 ggaaagaatt aactccaatt tccttcatca agtggaaatc ttcggtgtaa gtatgaaaaa
     3721 agttactggc tacaagaggt ccgacattat cgaaaaaatc ttctggatgc gttttgaacc
     3781 agtagtccat cacattttca tgtacttttc catattgacc ttctgtctga ggtccgctag
     3841 aagcagctcc ccaccaaaac agattaggaa atactaactt ttttttcatg ctcaacctcc
     3901 tttctattat tctatacata aagtatagca taattttaaa atttgtctag acatttttaa
     3961 aaattgttga tacatatctt gtgtttgcct catttcttga actttgttat actactatta
     4021 gaatattata gagagaacca gattaaatga gtacaaaata tttatttatt tacaatgaga
     4081 ttcgtgaaaa gattctttgt aataaatata ccatgaacga acaattgcct gatgaaatga
     4141 cattagctaa acagtttgcc tgtagtcgaa tgacgatcaa aaaagcttta gacttgttag
     4201 tttctgaggg cttaattttt agaaaacgtg ggcagggaac ctttgttctc tctcgtggca
     4261 gctcaaaaag aaaattaatc gttccagaaa gagatatccg gggactgaca aaaatatctg
     4321 aagatgctca ttctacaatt gactcgagga ttattcactt caaattagaa tttgcaaatg
     4381 aatttttagc agaaaaacta caggtcgctt tgcagagtcc agtttataat atttaccgtc
     4441 tgcgtattat tgacggtaaa ccttatgttc tggaacaaac ttatatgagt accgatgtta
     4501 ttccaggtat tactgaagat attttacaaa aatcgattta caattacatt gaaggaaagt
     4561 taggattgca tattgccagt gctacaaaaa tcttgcgagc ttcttctagt tcagaaaatg
     4621 agcaacatta cttgcagctc cttccaacgg aaccggtatt tgaagtagaa caagtggctt
     4681 atttggataa cggaactccg tttgagtact cgattagtcg tcatcgctat gatttatttg
     4741 aatttaattc ttttgcatta cgacattcct cctaggagaa aatgtgaaaa tgaagccaat
     4801 cttttacaga ctctagttta agaaaaattt aaaacagggc aagaaggtcc catctatgct
     4861 taaatggttt ctcttttcta aataagatgg ctttaaaaga gtgatcgttt tatccatcat
     4921 gttgaaaaat atcttcgtat agcttataga gtaggtactg aaattgttca cctgatctac
     4981 ttcttatagt tatttagttt taaatagtgt ttcaaacatt cttacactga cgagaagttt
     5041 ttgagtcttt tcttgtaaca catatagtat actgaggtta gaatagtaga ctgtgacttc
     5101 taaaaaattg ctagaaatga atttcaatct cccaatttat ttgttcatat cttcttttaa
     5161 tatattaaat aaattctgaa tcataatcat ttaaaaaaat tttatttttt atttttcatt
     5221 acgaataata tagatgaagg ggaaagagta tgaaaacaga actgtttctt ttgctattag
     5281 ttcaaaagga gaaaaaatga aagtagaaaa tatttcgtat agggtggatc atcgtatatt
     5341 gtttgataat atttcttttg atacttcgag ttcaggcgtg acattaatta ctggtaaaaa
     5401 tggtacagga aagtcaactt tactatagta gattgaaact agaatagtac acatctactt
     5461 ctaaaatatt gttagaaatc gatttgacta tcctgatcta tttgtcctgt tcttatttca
     5521 tttcactata tctcaaattg agtatgacga agtgcgctcc catgtcctgg gaacgcactt
     5581 cgtcatattt ttcatattct tgaatccatc gataaagact attgggatga atttttaaag
     5641 ttgaactaat tatttttaca ggatgaggtt tacagcagag agtttgaagg ctttatcaaa
     5701 ggtttttctt ggcataatga cttttcctcg tttccactta attttgtgtc tactttatta
     5761 taccaagtcc acccttaagt tagataatga atctaactta aggaagctag aaggatgaga
     5821 atccaggtgg tcaagagtcc caaacttaag ctgataggga cacccagaat aatttgcttt
     5881 ttgaaggcaa gaccgcgttc ctctatattg gggagtgaga gttgaatgag agaaccagct
     5941 gatgaaaagg gtgagatatt agtagataga gcgccaataa cggtggctgt tgtgagtaag
     6001 tgaatatcaa tctgaggatt ttgagcactg atgatagcaa tgatgggaaa gagggctgga
     6061 gctacaacgg atagggtgga actaaagagt gacatcactc cggctatcac acaaaagaac
     6121 agaggtaacc agaaatgagg aatggttgtt gtcatgaggt gccctatcag tgtgactaaa
     6181 cctgacttga ccgctagaga cattagtaag ctcatgccgc agagcatgat aattgtagcc
     6241 cagggaactt tagccaaaat ggcttcttgc ttccctaatt tgagccttaa ggcgaggcag
     6301 accatgagta ttgagacaaa gccaatatca aatgtttttt gataagtagc tatccaggcg
     6361 atgtttggga aaatgagatg caacaaggga aaaagccaaa ccaaaaccat gctgctgatc
     6421 atgagcaagg tggtttgtct ttgaaccttg ctgaggagtg gtggttggtc aatagtcaag
     6481 gatgagtttg ttcttccctt actatagtgg ctgtaacagg ataataaaag caagacgatg
     6541 agtgggtaga taatgctgac gataaagata tgattgccaa gtgaaaaagc ttgctcttcc
     6601 catcccattt gcttaaacag gccttgaaag acaatgcctg agctactggt tatcaaatta
     6661 gcccctcctg aagctcccca attgacggct tgagctccaa tcaaagggtg tttgtccgct
     6721 ttttgacaga gggtaatcgc tagaggacag caaacggcca tagtagtgaa aaatccagca
     6781 cctaaagcag acaaaagggt tgccatcagg tataaaatca tgtagagggc gttaggatgg
     6841 gtgcgtgtgc ggtagagaat gtgttgagcc aagacatcaa gagtaccgtt agttgttgca
     6901 acgttataaa agagagagac gctaaaaatg gtaaaaaaga gtgaggttgg ccaaaaatga
     6961 agaagttctt tggggcttaa tcccatgaga gtggttgcga tgaggtaaga aaaagcaata
     7021 gccagcaggc caatattgat tttggtgcgg taaccaattc caatggctag agcaatggcg
     7081 ctaatcatta ttaaatgaat cattgaattg tcctttcagt tagaatatgg aaataggttg
     7141 gcaattttgg cgctcaaaag accacctgtt tcctattggt acttgactat tatacacaaa
     7201 aaaaatacaa ttgtcttgac aattgtattg acacttgtta gaattaaaaa tgaggtattc
     7261 aggcttgtga tttcctatgg aagttcatag tgattgcctc tagtgcttac aagtgatatt
     7321 aaaaatagag gatctagtga tgtcaatcat ttcaactgat ttaacccctt ttcaaataga
     7381 tgatacattg aaagcagcct tgcgagaaga tgttcattcc gaagattaca gtaccaatgc
     7441 catttttgat catcatggcc aagccaaggt gtcgcttttt gccaaggaag ctggtgtttt
     7501 agcggggcta accgtttttc aaagggtttt taccctattt gatgccgagg tgaccttcca
     7561 gaatcctcat caatttaagg atggggatcg tttgactagt ggcgatttgg ttttagaaat
     7621 cataggctcg gtgagaagtc tcttaacatg tgaacgcgtt gccttgaatt ttttacaaca
     7681 tttatcaggg attgcttcga tgacagctgc ttatgtagaa gccttaggcg atgattgcat
     7741 taaggtattt gatactcgaa aaactactcc taatttacgt ctttttgaga aatatgccgt
     7801 gagagttggc ggtggctata atcatcgctt taatttatca gatgctatcc tgctaaaaga
     7861 caatcacatt gcggcagtag gtagtgttca aaaggcaatt gctcaagcgc gtgcctatgc
     7921 cccttttgtg aaaatggtcg aggtggaagt ggaaagcctt gctgctgccg aagaagctgc
     7981 ggcggcgggt gctgatatta tcatgttgga taatatgtca ttggaacaga ttgaacaggc
     8041 cattacccta attgcaggac gttctcggat tgaatgttct ggaaatattg atatgaccac
     8101 tattagccgt tttcgtggtt tagcgattga ttacgtctcc agtggtagtt taacccatag
     8161 tgctaagagt cttgattttt ccatgaaggg gttaacctac cttgatgtct aagttgtaaa
     8221 ataaactaac tttttaaagg atgtctttcc tctagaacga gttttatgtc agatagttta
     8281 aacgcctctt caaatatagt aaaatgaacc aaaaatagta cacaatg
//
LOCUS       DAVBOG010000071         8260 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.072, whole genome shotgun sequence.
ACCESSION   DAVBOG010000071 DAVBOG010000000
VERSION     DAVBOG010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 8260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8260
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.072"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            226..6657
                     /locus_tag="VQ865_001963"
     CDS             226..6657
                     /locus_tag="VQ865_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000750079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S8 family serine peptidase"
                     /protein_id="HET3136258.1"
                     /translation="MKKSTVLSLTTAAVILAAYAPNEVVLADTSSSEDALSISDKEKV
                     VVDKETENKEKHKDIHNAIETSKDTEEKKTTIIEEKEVVSKNPVIDTKTSNEEARIKE
                     DSNQSQGDNAHSSANKGTENPKKEDRLVYIAEFKDKESGEKAIKGLSNLKNTKVLYTY
                     DRIFNGSAIETTPDNLDKIKQIEGISSVERAQKVQPMMNHARKEIGVEEAIDYLKSIN
                     APFGKNFDGRGMVISNIDTGTDYRHKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKI
                     PHAFNYYNGGKITVEKYDDGRDYFDPHGMHIAGILAGNDTEQDIKNFNGIDGIAPNAQ
                     IFSYKMYSDAGSGFAGDETMFHAIEDSIKHNVDVVSVSSGFTGTGLVGEKYWQAIRAL
                     RKAGIPMVVATGNYATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDAIAVASAKNQT
                     VEFDKVNIGGESFKYRNIGAFFDKNKITTNEDGTKAPSKLKFVYIGKGQDQDLIGLDL
                     RGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWTELPAMGYEADEGT
                     KSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVG
                     DEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVSAPGKNIKSTLNVIN
                     GKSTYGYMSGTSMATPIVAASTVLIRPKLKEMLERPVLKNLKGDDKIDLTSLTKIALQ
                     NTARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFKNTDSKGLVNSYGS
                     ISLKEIKGDKKYFTIKLHNTSNRPLTFKVSASAITTDSLTDRLKLDETYKDEKSPDGK
                     QIVPEIHPEKVKGANITFEHDTFTIGANSSFDLNAVINVGEAKNKNKFVESFIHFESV
                     EEMEALNSNGKKINFQPSLSMPLMGFAGNWNHEPILDKWAWEEGSRSKTLGGYDDDGK
                     PKIPGTLNKGIGGEHGIDKFNPAGVIQNRKDKNTTSLDQNPELFAFNNQGINAPSSSG
                     SKIANIYPLDSNGNPQDAQLERGLTPSPLVLRSAEEGLISIVNTNKEGENQRDLKVIS
                     REHFIRGILNSKSNDAKGIKSSKLKVWGDLKWDGLIYNPRGREENAPESKDNQDPATK
                     IRGQFEPIAEGQYFYKFKYRLTKDYPWQVSYIPVKIDNTAPKIVSVDFSNPEKIKLIT
                     KDTYHKVKDQYKNETLFARDQKEHPEKFDEIANEVWYAGAALVNEDGEVEKNLEVTYA
                     GEGQGRNRKLDKDGNTIYEIKGAGDLRGKIIEVIALDGSSNFTKIHRIKFANQADEKG
                     MISYYLVDPDQDSSKYQKLGEIAESKFKNLGNGKEGSLKKDTTGVEHHHQENEESIKE
                     KSSFTIDRNISTIRDFENKDLKKLIKKKYKEEDDFVTGGKRTVELDYKYDDKGNITAY
                     EDESALEYETEKFDEIKSKIYGVLSPSKDGHFEILGKISNVSKNAKVYYGNNYKFIEI
                     KATKYDSHSKTMIFDLYANINDIVDGLAFAGDMRLFVKDDNQIKAETKIRMPEKNKET
                     KAEYPYVSSYGNVIELGEGDLSKNKPDNLTKMESGKIYSDSEKQQYLLKDNIILRKGY
                     ALKVTTYNPGKTDMLEGNGVYSKEDIAKIQKANPNLRVLSETTIYADSRNVEDGRSTQ
                     AVLMSALDGFNIIRYQVFTFKMNDKGEAIDKDGNLVTDSSKLVLFGKDDKEYTGEDKS
                     NVEAIKEDGSMLFIDTKPVNLSMDKNYFNPSKSNKIYVRNPEFYLRGKISDKGGFNWE
                     LRVNESVVDNYLIYGDLHIDNTRDFNIKLNVKDGDIMDWGMKDYKANGFPDKVTDMDG
                     NVYLQTGYSDLNAKAVGVHYQFLYDNVKPEVNIDPKGNTSIEYADGKSVVFNINDKRN
                     NGFDGEIQEQHIYVNGKEYTSFDDIKQITDKTLNIKIVVKDFARNTTVKEFILNKDTG
                     EVSELKPHRVTVTIQNGKEMSSTIVSEEDFILPVYKGELEKGYQFDGWEISGFEGKKD
                     AGYVINLSKDTFIKPVFKKIEEKKEEENKPTFDVSKKKDNPQVNHSQLNESHRKEDLQ
                     REDHSQKSDSTKDVTATVLDKNNISSKSTTNNPNKLPKTGTASGAQTLLAAGIMFIVG
                     IFLGLKKKNQD"
     gene            complement(6953..7299)
                     /locus_tag="VQ865_001964"
                     /pseudo
     CDS             complement(6953..7299)
                     /locus_tag="VQ865_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014632353.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(7394..7579)
                     /locus_tag="VQ865_001965"
                     /pseudo
     CDS             complement(7394..7579)
                     /locus_tag="VQ865_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            7607..7834
                     /locus_tag="VQ865_001966"
     CDS             7607..7834
                     /locus_tag="VQ865_001966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001827253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3136259.1"
                     /translation="MRERLLTQPLLHADETSYRVLESHSHLTYYWTFLSGKVENQAIT
                     LYHHDQSRSGSVVQEFLGDYSGYVHCDMLRQ"
     gene            7910..8260
                     /locus_tag="VQ865_001967"
                     /pseudo
     CDS             7910..8260
                     /locus_tag="VQ865_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         3138 a         1163 c         1623 g         2336 t
ORIGIN      
        1 taatcttatt ttttaacgtg tgctaaaaaa taaattaatg catgttaatt tttcttgaat
       61 taaatttttt taaatgatat actgttttta tggagagata acaattatat ataaatgtac
      121 tactctattt cctagataat acttagtaaa actttttata acaaaggcta gcaaagttaa
      181 agtttattat ctattggaag ttatataaat atgtaaggaa ttaaaatgaa aaaaagtaca
      241 gtattgtcat taactacagc tgcagttatt ttagcagcct atgcccctaa tgaggtagtc
      301 ttagcagaca catctagctc tgaagatgct ttaagcatct ctgataaaga aaaagtagta
      361 gtagataagg aaacagaaaa taaagagaaa cataaagata ttcataatgc tatagaaact
      421 tcaaaggata ctgaagaaaa gaaaacaaca attattgagg aaaaagaagt tgttagtaaa
      481 aatcctgtga tagacactaa aactagcaat gaagaagcaa gaatcaaaga agattccaat
      541 caatcccaag gagataatgc acactcgtct gcaaataaag gcacagaaaa tccgaaaaaa
      601 gaagatagac ttgtctatat tgctgaattt aaagataaag aatctggaga aaaagcaatc
      661 aagggactat caaatcttaa gaatacaaaa gttttatata cttatgatag aatttttaac
      721 ggtagtgcca tagaaacaac tccagataac ttggacaaaa ttaaacaaat agaaggtatt
      781 tcatcggttg aaagggcaca aaaagtccaa cccatgatga atcatgccag aaaggaaatt
      841 ggagttgagg aagctattga ttacctaaag tctatcaatg ctccatttgg gaaaaatttt
      901 gatggtagag gtatggtcat ttcaaatatc gatactggaa cagattatag acataaggct
      961 atgagaatcg atgatgatgc caaagcctca atgagattta aaaaagaaga cttaaaagga
     1021 actgataaaa attattggtt gagtgataaa atccctcatg cgttcaatta ttataatggt
     1081 ggcaaaatca ctgtagaaaa atatgatgat ggaagggatt attttgaccc acatgggatg
     1141 catattgcag ggattcttgc tggaaatgat actgaacaag atatcaaaaa ctttaacggc
     1201 atagatggaa ttgcacctaa tgcacaaatt ttctcttaca aaatgtattc tgacgcagga
     1261 tctgggtttg cgggtgatga aacaatgttt catgctattg aagattctat caaacacaac
     1321 gttgatgttg tttcggtatc atctggtttt acaggaacag gtcttgtagg tgagaaatat
     1381 tggcaagcta ttagggcatt aagaaaagca ggcattccaa tggttgtcgc tacgggtaac
     1441 tatgcgactt ctgcttcaag ttcttcatgg gatttagtag caaataatca tctgaaaatg
     1501 accgacactg gaaatgtaac acgaactgca gcacatgagg atgcgatagc ggtcgcttct
     1561 gctaaaaatc aaacagttga gtttgataaa gttaacatag gtggagaaag ttttaaatac
     1621 agaaatatag gggccttttt cgataagaat aaaatcacaa caaatgaaga tggaacaaaa
     1681 gctcctagta aattaaaatt tgtatatata ggcaaggggc aagaccaaga tttgataggt
     1741 ttggatctta ggggcaaaat tgcagtaatg gatagaattt atacaaagga tttaaaaaat
     1801 gcttttaaaa aagctatgga taagggtgca cgcgccatta tggttgtaaa tactgtaaat
     1861 tactacaata gagataattg gacagagctt ccagctatgg gatatgaagc ggatgaaggt
     1921 actaaaagtc aagtgttttc aatttcagga gatgatggtg taaagctatg gaacatgatt
     1981 aatcctaata aaaaaactga agtcaaaaga aataataaag aagattttaa agataaattg
     2041 gagcaatact atccaattga tatggaaagt tttaattcca acaaaccgaa tgtaggtgac
     2101 gaaaaagaga ttgactttaa gtttgcacct gacacagaca aagaactcta taaagaagat
     2161 atcatcgttc cagcaggatc tacatcttgg gggccaagaa tagatttact tttaaaaccc
     2221 gatgtttcag cacctggtaa aaatattaaa tccacgctta atgttattaa tggcaaatca
     2281 acttatggct atatgtcagg aactagtatg gcgactccaa tcgtggcagc ttctactgtt
     2341 ttgattagac cgaaattaaa ggaaatgctt gaaagacctg tattgaaaaa tcttaaggga
     2401 gatgacaaaa tagatcttac aagtcttaca aaaattgccc tacaaaatac tgcgcgacct
     2461 atgatggatg caacttcttg gaaagaaaaa agtcaatact ttgcatcacc tagacaacag
     2521 ggagcaggcc taattaatgt ggccaatgct ttgagaaatg aagttgtagc aactttcaaa
     2581 aacacggatt ctaaaggttt ggtaaactca tatggttcca tttctcttaa agaaataaaa
     2641 ggtgataaaa aatactttac aatcaagctt cacaatacat caaacagacc tttgactttt
     2701 aaagtttcag catcagcgat aactacagat tctctaactg acagattaaa acttgatgaa
     2761 acatataaag atgaaaaatc tccagatggt aagcaaattg ttccagaaat tcacccagaa
     2821 aaagtcaaag gagcaaatat cacatttgag catgatactt tcactatagg cgcaaattct
     2881 agctttgatt tgaatgcggt tataaatgtt ggagaggcca aaaacaaaaa taaatttgta
     2941 gaatcattta ttcattttga gtcagtggaa gaaatggaag ctctaaactc caacgggaag
     3001 aaaataaact tccaaccttc tttgtcgatg cctctaatgg gatttgctgg gaattggaac
     3061 cacgaaccaa tccttgataa atgggcttgg gaagaagggt caagatcaaa aacactggga
     3121 ggttatgatg atgatggtaa accgaaaatt ccaggaacct taaataaggg aattggtgga
     3181 gaacatggta tagataaatt taatccagca ggagttatac aaaatagaaa agataaaaat
     3241 acaacatccc tggatcaaaa tccagaatta tttgctttca ataaccaagg gatcaacgct
     3301 ccatcatcaa gtggttctaa gattgctaac atttatcctt tagattcaaa tggaaatcct
     3361 caagatgctc aacttgaaag aggattaaca ccttctccac ttgtattaag aagtgcagaa
     3421 gaaggattga tttcaatagt aaatacaaat aaagagggag aaaatcaaag agacttaaaa
     3481 gtcatttcga gagaacactt tattagagga attttaaatt ctaaaagcaa tgatgcaaag
     3541 ggaatcaaat catctaaact aaaagtttgg ggtgacttga agtgggatgg actcatctat
     3601 aatcctagag gtagagaaga aaatgcacca gaaagtaagg ataatcaaga tcctgctact
     3661 aagataagag gtcaatttga accgattgcg gaaggtcaat atttctataa atttaaatat
     3721 agattaacta aagattaccc atggcaggtt tcctatattc ctgtaaaaat tgataacacc
     3781 gcccctaaga ttgtttcggt tgatttttca aatcctgaaa aaattaagtt gattacaaag
     3841 gatacttatc ataaggtaaa agatcagtat aagaatgaaa cgctatttgc gagagatcaa
     3901 aaagaacatc ctgaaaaatt tgacgagatt gcgaacgaag tttggtatgc tggcgccgct
     3961 cttgttaatg aagatggaga ggttgaaaaa aatcttgaag taacttacgc aggtgagggt
     4021 caaggaagaa atagaaaact tgacaaagac ggaaatacca tttatgaaat taaaggtgcg
     4081 ggagatttaa ggggaaaaat cattgaagtc attgcattag atggttctag caatttcaca
     4141 aagattcata gaattaaatt tgctaatcag gctgatgaaa aggggatgat ttcctattat
     4201 ctagtagatc ctgatcaaga ttcatctaaa tatcaaaagc ttggcgagat tgcagaatct
     4261 aaatttaaaa atttaggaaa tggaaaagag ggtagtctaa aaaaagatac aactggggta
     4321 gaacatcatc atcaagaaaa tgaagagtct attaaagaaa aatctagttt tactattgat
     4381 agaaatattt caacaattag agactttgaa aataaagacc taaagaaact cattaaaaag
     4441 aaatataagg aagaagacga ctttgtaact ggtggaaaaa gaacagtaga acttgattat
     4501 aaatatgacg ataaaggaaa tataactgcc tatgaagatg aaagtgctct agaatatgaa
     4561 actgaaaaat ttgacgaaat aaaatcaaaa atttatggtg ttctaagccc atctaaagat
     4621 ggacactttg aaattcttgg aaagataagc aatgtttcta aaaatgccaa ggtatattat
     4681 ggaaataact ataaatttat agaaatcaaa gcgactaagt atgactcaca ttcaaaaacg
     4741 atgatatttg atttatacgc taatattaat gatattgtag atggattagc ttttgctgga
     4801 gatatgagat tatttgttaa agatgacaat caaataaaag ctgaaactaa aattagaatg
     4861 cctgaaaaaa ataaggaaac taaagcagaa tatccgtatg tatcaagtta tgggaatgta
     4921 atcgaattag gagaaggaga cctttcaaaa aacaaaccag acaatttaac taaaatggaa
     4981 tctggtaaaa tctattctga ttcagaaaaa caacaatatc tgttaaagga taacatcatt
     5041 ctaagaaaag gctatgcact aaaagtgact acctataatc ctggaaaaac ggatatgtta
     5101 gaaggaaatg gagtctatag caaggaagat atagcaaaaa tacaaaaggc caatcctaat
     5161 ctaagagtcc tttcagaaac aacaatttat gctgatagta gaaatgttga agatggaaga
     5221 agtacccaag ctgtattaat gtcggctttg gacggcttta acattataag gtatcaagtg
     5281 tttacattta aaatgaacga taaaggggaa gctatcgata aagacggaaa tcttgtgaca
     5341 gattcttcta aacttgtatt atttggtaag gatgataaag aatacactgg agaggataag
     5401 tccaatgtag aagctataaa agaagatggc tccatgttat ttattgatac caaaccagta
     5461 aacctttcaa tggataagaa ctactttaat ccatctaaat ctaataaaat ttatgtacga
     5521 aatccagaat tttatttaag aggtaagatt tctgataagg gtggttttaa ctgggaattg
     5581 agagttaatg aatcggttgt agataattat ttaatctacg gagatttaca cattgataac
     5641 actagagatt ttaatattaa gctgaatgtt aaagacggtg acatcatgga ctggggaatg
     5701 aaagactata aagcaaacgg atttccagat aaggtaacag atatggatgg aaatgtttat
     5761 cttcaaactg gctatagcga tttgaatgct aaagcagttg gagtccacta tcagttttta
     5821 tatgataatg ttaaacccga agtaaacatt gatcctaagg gaaatactag tatcgaatat
     5881 gctgatggaa aatctgtagt ctttaacatc aatgataaaa gaaataatgg attcgatggt
     5941 gagattcaag aacaacatat ttatgtaaat ggaaaagaat atacatcatt tgatgatatt
     6001 aaacaaataa cagacaagac actaaacatt aagattgttg taaaagattt tgcaagaaat
     6061 acaaccgtaa aagaattcat tttaaataaa gatacgggag aggtaagtga attaaaacct
     6121 catagggtaa ctgtgaccat tcaaaatgga aaagaaatga gttcaacgat agtgtcggaa
     6181 gaagatttta ttttacctgt ttataagggt gaattagaaa aaggatacca atttgatggt
     6241 tgggaaattt ctggtttcga aggtaaaaaa gacgctggct atgttattaa tctatcaaaa
     6301 gataccttta taaaacctgt attcaagaaa atagaggaga aaaaggagga agaaaataaa
     6361 cctacttttg atgtatcgaa aaagaaagat aacccacaag taaaccatag tcaattaaat
     6421 gaaagtcaca gaaaagagga tttacaaaga gaagatcatt cacaaaaatc tgattcaact
     6481 aaggatgtta cagctacagt tcttgataaa aacaatatca gtagtaaatc aactactaac
     6541 aatcctaata agttgccaaa aactggaaca gcaagcggag cccagacact attagctgcc
     6601 ggaataatgt ttatagtagg aatttttctt ggattgaaga aaaaaaatca agattaagat
     6661 aaaagctata gaaaaaaatg gtttatgtac tgagattaga tagtgaggtg atgacatagt
     6721 tttgtgaaaa tagccattta taactcaatt atttagttta ctttacttta ctagtgatac
     6781 tatttggagt tattaatgga cttagtttat ataactaatg aattgattga aagggttagt
     6841 attgacaata ttggtcatat tgactagaaa atagagtcta tcaaaattta aaggctaata
     6901 gaggtgatga gacaatttcg gctctttgtc aactgtagtg ggttgaagtc agctaagctc
     6961 gagaaaggac aaattttgtc ctttcttttt tgatattcag agcgatgaaa atccgttttt
     7021 tgaagttttc aaagtttcga aaaccaaagg cattgcgctt gataagtttg atgagattat
     7081 tggtcgcttc cagtttggca ttagaatagt gtagttgaag ggcattgaca atcttctctt
     7141 tatctttgag gaaggtttta gaggatgaac ttgattcaga ttgtcctcaa tgagtccgaa
     7201 aaatttgtca ggctccttat tctgaaagtg aaaaagcaag agttgataga gattatagtg
     7261 gtgtttcaag tcttctgaat agctcaaaag tttatctata gtagattgaa actagaatag
     7321 tacacctctg cttctaaaac attgttagaa atcgatttga ctgtcctgaa tgatttgtcc
     7381 tgttattatt tcattttact ataaatccac gtttacgaat ctctttccac acttgttcaa
     7441 tggggttcat ctctggtgtg tatggaggaa taaatgcaaa accaatatta gtcggaatct
     7501 ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaga taatcatctg
     7561 gataagcttg tgaaagctcc tattcctaaa gcccctttat aacctcttgc gagagagact
     7621 attgactcag cccttacttc atgcggatga aacttcttat cgggttctag agagtcatag
     7681 ccatctgacc tactattgga cctttttgtc tgggaaagtt gagaatcaag caatcacgct
     7741 gtaccatcat gatcagagtc ggagtggttc ggtagtacaa gaattcctag gagattattc
     7801 tggctatgtt cattgtgata tgttgcggca gtaacttagg actttagtcc tctagttctg
     7861 cctatgcgat agcagtccaa ggtttaggag caaggcgacg ctaagcttgg taaactgcga
     7921 accgctagaa gcttatcgtc aactggcaga agctgaactt gttggatgtt gggcgcatgt
     7981 gagaaggaaa ttttttgaag cgacccccaa gcaagcagat aaatcatcct taggagctaa
     8041 aggtttagct tattgtgatc agttattttc cttggaaaga gactgggagg ctttgccagc
     8101 tgatgaacga ctacagaaac gtcaagaaca tctccagccc ctaatggaag acttctttgc
     8161 ttggtgccgc cgtcagtcag ttttagcagg ttcaaaacta ggaagggcaa ttgaatacag
     8221 cctcaagtat aaagaaacct ttaagactat tttgaaagac
//
LOCUS       DAVBOG010000072         7476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.073, whole genome shotgun sequence.
ACCESSION   DAVBOG010000072 DAVBOG010000000
VERSION     DAVBOG010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.073"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            149..304
                     /locus_tag="VQ865_001968"
                     /pseudo
     CDS             149..304
                     /locus_tag="VQ865_001968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000710121.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
     gene            504..3779
                     /gene="rexB"
                     /locus_tag="VQ865_001969"
     CDS             504..3779
                     /gene="rexB"
                     /locus_tag="VQ865_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent nuclease subunit B"
                     /protein_id="HET3136260.1"
                     /translation="MKLLYTDIRTSLTEILTREAEELVAAGKRVFYIAPNSLSFEKER
                     AVLECLSQQASFSITVTRFAQMARYLVLNDLPAKTTLDDIGLGLAFYKCLAELDPKDL
                     RVYGAIKQDPQLIQQLIELYHEMTKSQMSFLDLENLTDEDKRADLLLIFEKVTAYLNQ
                     GQLAQGSQLSHLIEAIENDKVSSDFNQITLVIDGFTRFSAEEERVVDLLHGKGVEIVI
                     GAYASKKAYTSPFSEGNLYQASVKFLHHLASKYQTPAQDCSQTHEKMDSFDKASRLLE
                     SSYDFSELALDVDEKDRENLQIWSCLTQKEELELVARSIRQKLHENSDLSYKHFRILL
                     GDVASYQLSLKTIFDQYQIPFYLGRSEAMAHHPLTQFVESILALKRYRFRQEDLINLL
                     RTDLYTDLSQSDIDAFEQYIRYLGINGLPAFQQIFTKSHHGKFNLERLNVLRLRILAP
                     LETLFASRKQKAENLLQKWSVFLKEGAVTKQLQDLTTTLEAVEQERQAEVWKAFCHVL
                     EQFATVFAGSQVSLEDFLALLHSGMSLSQYRTIPATVDTVLVQSYDLIAPLTADFVYA
                     IGLTQDNLPKISQNTSLLTDEERQNLNQATEEGVQLLIASSENLKKNRYTMLSLVNSA
                     RKQLFLSAPSLFNESESKESAYLQELIHFGFRRREKRMNHKGLSKEDMGSYHSLLSSL
                     VAYHQQGEMSDTEQDLTFVKVLSRVIGKKLDLQGLENPAIPTSPSSKTLAKDTLQALY
                     PAKQEFYLSTSGLTEFYRNEYSYFLRYVLGLQEELRLRPDARSHGNFLHRIFERALQL
                     PNEDSFDQRLEQAIQETSQEREFEAIYQESLEAQFTKEVLLDVARTTGHILRHNPAIE
                     TIKEEANFGGKDQAFIQLDNGRSVFVRGKVDRIDRLKANGAIGVVDYKSSLTQFQFPH
                     FFNGLNSQLPTYLAALKREGKQNFFGAMYLEMAEPVQSLMAVKSLAGAVVEASKSMKY
                     QGLFLEKESSYLGEFYNKNKANQLTDEEFQLLLDYNAYLYKKAAEKILAGRFAINPYT
                     ENGRSIAPYVQQHQAITGFEANYHLGQARFLEKLDLADGKRLVGEKLKQAWFEKIREE
                     LNR"
     gene            3776..7426
                     /gene="addA"
                     /locus_tag="VQ865_001970"
     CDS             3776..7426
                     /gene="addA"
                     /locus_tag="VQ865_001970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HET3136261.1"
                     /translation="MKLIPFLSEEEIQKLQEAEANSSKEQKKTAEQIEAIYTSGQNIL
                     VSASAGSGKTFVMAERILDQLARGVEISQLFISTFTVKAATELKERLEKKISKKIQET
                     DDVDLKQHLGRQLADLPNAAIGTMDSFTQKFLGKHGYLLDIAPNFRILQNQSEQLLLE
                     NEVFHEVFEAHYQGKQKESFSHLLKNFAGRGKDERGLRQQVYKIYDFLQSTSNPQKWL
                     SESFLKGFEKADFTSEKEKLTEQIKQALWDLERFFRYHLDNDAKEFAKAAYLENVQLI
                     LDEIGSLNQEFDSQAYQAVLARVVAISKEKNGRALTNASRKADLKPLADAYNEERKTQ
                     FTKLGQLSDQIAILDYQERYHGDTWKLAKTFQSFMSDFVEAYRQRKRQENAFEFADIS
                     HYTIEILENFPQVRESYQERFHEVMVDEYQDTNHIQERMLELLSNGHNRFMVGDIKQS
                     IYRFRQADPQIFNEKFQRYAQNPQEGKLILLKENFRSSSEVLSATNDVFERLMDQEVG
                     EINYDNKHQLVFANTKLTPNPDNKAEFLLYDKDDTGEEEESQTETKLTGEMRLVIKEI
                     LKLHQEKGVAFKEIALLTSSRSRNDQILLALSEYGIPVKTDGEQNNYLQSLEVQVMLD
                     TLRVIHNPLQDYALVALMKSPMFGFDEDELARLSLQKAEDKVHENLYEKLVNAQKMAS
                     SQKGLIHTALAEKLKQFMDILASWRLYAKTHSLYDLIWKIYNDRFYYDYVGALPNGPA
                     RQANLYALALRADQFEKSNFKGLSRFIRMIDQVLEAQHDLSSVAVAPPKDAVELMTIH
                     KSKGLEFPYVFILNMDQDFNKQDSMSEVILSRQNGLGVKYIAKMETGAVEDHYPKTIK
                     LSIPSLTYRQNEEELQLASYSEQMRLLYVAMTRAEKKLYLVGKGSREKLEVKQYPAAK
                     NGKLNSNTRLQARNFQDWLWAISKVFTKDKLNFSYRFIGEDQLTREAIGELETKSPLQ
                     DSSQADNRQSDTIKEALEMLKEVEVYNTLHRAAIELPSVQTPSQIKKFYEPVMDMEGV
                     EIAGQGQSVGKKISFDLPDFSTKEKVTGAEIGSATHELMQRIDLSQQLTLASLTETLK
                     QVQTSQAVRDKINLDKILAFFDTVLGQEILANTDHLYREQPFSMLKRDQKSQEDFVVR
                     GILDGYLLYENKIVLFDYKTDRYDEPSQLVDRYRGQLALYEEALSRAYSIENIEKYLI
                     LLGKDEVQVVKV"
BASE COUNT         2275 a         1573 c         1591 g         2037 t
ORIGIN      
        1 tactattttt ggttcatttt actatagtag attgaaataa gatacgaaca gcttgattag
       61 ggaaatcaaa ttaatttcta gaaatatttt agcatccacg gtgtactatt atagtttcaa
      121 tttactatag ttcaatcatt ctatcaagaa tattgaatat ataaaggcac gtaatattaa
      181 aacttcttct gatatcgaat tagagtccga tgttgatggc gataaatcag acaatctacc
      241 agtcgacatt aagatactgg gacaacacat tgaagtgtat tccgtaccta agaaacaatc
      301 ataaaactca aagccttgtt accgaggctt ttttattatg tgattttcag tagccagact
      361 tattctatct aatacaagta aagctaagta tttaagattt agcagatgat gaagaaaaga
      421 aaggatggcc taaatatttt aacagattta cgaggctaat catggtataa tatagggtga
      481 tgaaaaattc caacgaggct gagatgaaat tactttatac tgatattcgg acttctttga
      541 cagaaattct aacaagagag gcagaagagc tagttgcagc tggcaagcgg gtcttctaca
      601 ttgcccccaa ctctctttct tttgaaaagg aacgcgccgt gctggaatgc ttgtcccagc
      661 aggcttcttt ttcgattacc gtcacgcgct ttgctcaaat ggctcgttat ctggtcttga
      721 atgatttacc agctaaaact actcttgatg atatcggtct tgggttggcc ttttacaaat
      781 gccttgccga actcgatccc aaggacttgc gtgtttatgg cgctattaag caggatcctc
      841 aattgatcca gcagttaatt gagctttacc atgagatgac caaatcccag atgagttttt
      901 tggacttgga gaatttaaca gatgaggata agagggcgga tttactcttg atttttgaga
      961 aagtaacagc ctatcttaat caaggtcagt tagcccaggg aagtcagttg tcccatttga
     1021 ttgaggctat tgagaatgac aaggtaagta gtgattttaa tcaaatcacc ttggtcattg
     1081 acggctttac tcgtttttct gctgaggaag agcgggttgt ggacttactt cacggcaaag
     1141 gtgttgagat tgttatcggg gcttatgcta gtaagaaagc ctataccagt ccttttagcg
     1201 agggcaatct ctaccaagcc agcgtaaaat ttctccatca tctggcttct aaataccaaa
     1261 cgcctgctca ggactgttct caaactcatg agaagatgga tagttttgac aaggcctctc
     1321 gtttgttgga gtcttcttat gacttttcag aactcgcttt ggatgtcgat gagaaagacc
     1381 gtgaaaattt acaaatctgg tcttgtttga cgcaaaagga ggagttggag ctagtagccc
     1441 gtagtattcg tcagaaatta catgagaact cagacctgag ctacaagcat tttcgtattc
     1501 tcttggggga tgtagcttct taccagttat ctctcaaaac catttttgac cagtatcaga
     1561 ttccttttta tcttggtaga agcgaagcca tggctcatca tcccttgact cagtttgtcg
     1621 agtctatttt agctttaaaa cgttaccgtt ttcgtcagga ggatttgatt aatcttctta
     1681 gaactgattt gtatactgac ctcagtcagt ctgatattga tgcttttgag caatatatcc
     1741 gctatcttgg tatcaatggc ttgccagcct ttcagcaaat cttcaccaaa tcccaccatg
     1801 gaaaatttaa tcttgagcgt ttgaatgtcc tccgcctgag aattttagca cctcttgaaa
     1861 ccctctttgc cagccgaaaa caaaaggctg aaaacctcct acaaaaatgg agtgtctttc
     1921 taaaagaagg agctgtgacc aagcagttac aagatttgac aaccactttg gaagctgtag
     1981 aacaggaaag acaagccgaa gtttggaagg ctttctgcca tgttttagaa caatttgcga
     2041 ctgtttttgc tggttcacag gttagtctgg aagacttcct agccttgctc cattctggaa
     2101 tgagtttgtc ccaataccgt accattccag caacagtgga cactgttctg gtgcagagtt
     2161 acgatttgat tgcaccattg actgctgact ttgtctatgc tattggacta actcaggaca
     2221 atttaccaaa aatttctcaa aacaccagtc ttctgacaga tgaagaaagg caaaacctaa
     2281 accaagcgac cgaagaaggc gttcaattac tgattgccag cagtgaaaat ctcaagaaaa
     2341 atcgctacac tatgctttcc ttggtcaatt ctgctcgtaa gcagttgttc ttgtcggctc
     2401 caagcctttt taacgaaagt gaaagtaagg aatctgccta tcttcaagag ttgatccatt
     2461 ttggatttag gcggagagag aagaggatga atcacaaagg actgtctaag gaggatatgg
     2521 ggtcctatca cagtcttttg tctagtctgg ttgcctatca ccagcagggt gagatgagcg
     2581 atactgagca agatttgact tttgtcaagg ttctgtcgcg tgtcataggt aaaaaactag
     2641 atctgcaagg tctggaaaat ccagctatcc caaccagtcc aagcagcaag accttagcca
     2701 aggacacctt gcaagctctc tatcctgcca aacaggagtt ttacctgtct acgtcgggtt
     2761 tgacagagtt ttatcgcaat gaatacagtt atttcctacg ctacgtttta ggcttgcagg
     2821 aggaattacg tttgcgtcct gatgcccgta gtcacgggaa tttcttgcat cgtatctttg
     2881 aacgcgcctt acagttgcct aatgaagatt cctttgacca acgtctagaa caagctattc
     2941 aagaaaccag tcaagaacgc gaatttgaag ctatttatca agaaagtttg gaagcccagt
     3001 ttaccaagga agttttgctt gatgttgcac ggacgactgg acatattctc cgacacaatc
     3061 cagccatcga aaccatcaaa gaagaagcaa attttggtgg aaaagaccaa gcctttattc
     3121 aattagacaa tggacgcagt gtctttgtac gaggcaaggt ggaccggatt gaccgtttga
     3181 aagctaatgg agcgatagga gtagtagact acaaatccag tctgactcag ttccagtttc
     3241 ctcatttctt taatgggctc aattctcagt taccaaccta tcttgctgcc ctaaaaagag
     3301 aagggaagca gaactttttc ggcgccatgt acttggaaat ggctgaacct gtccaatctc
     3361 tgatggcggt aaaaagtctg gcaggagcag tggtagaagc cagcaaatct atgaaatacc
     3421 aagggctctt cttggaaaaa gaaagcagtt atttaggcga attttataac aaaaacaagg
     3481 ctaatcaact gacagatgag gaatttcagc tcctactgga ctacaatgcc tatctttaca
     3541 agaaagctgc tgagaagatt ttagcaggcc ggttcgccat caatccttat actgaaaatg
     3601 gcagaagcat tgccccatac gtccagcaac atcaggctat tacaggcttt gaagccaatt
     3661 accatctggg ccaagcccgt ttcctagaaa aattggacct agctgatggc aagcgtctgg
     3721 tcggagaaaa actcaagcaa gcttggtttg aaaaaataag agaggagtta aatcgatgaa
     3781 gcttattccc tttttaagtg aggaggagat tcaaaaactg caagaagcag aagcaaattc
     3841 gagcaaggaa cagaagaaaa ctgccgaaca aatcgaagct atctacactt ctggtcagaa
     3901 tatcctggtc tcagcatcgg ctggttctgg aaagaccttt gtcatggcag agcgcattct
     3961 ggaccaattg gcgcgtggtg tcgaaatttc tcaactcttt atctcaacct ttaccgtcaa
     4021 ggctgcaact gaacttaaag aacgtttaga gaaaaaaatc agcaagaaaa tccaagaaac
     4081 agatgatgtc gatctcaaac aacacttggg tcgccagttg gcagacctac ccaacgctgc
     4141 catcggaacc atggactctt tcacacaaaa attccttggc aaacatggtt atctgcttga
     4201 tattgcacct aatttccgta ttttacaaaa ccaaagcgag caacttcttc tcgaaaacga
     4261 agtctttcat gaggtctttg aagcgcatta ccaaggtaaa cagaaagaga gctttagtca
     4321 tttgctgaaa aactttgctg ggcgtggcaa ggacgaacgg ggtctgcggc agcaagtcta
     4381 taaaatctat gacttcctcc aatccaccag taatcctcaa aagtggctga gtgaatcttt
     4441 cctcaaaggc tttgagaaag ctgattttac cagtgaaaaa gaaaaactga ctgagcaaat
     4501 caaacaagcc ctctgggatt tggaaagatt tttccgttac catctggata acgatgccaa
     4561 ggagtttgca aaggctgcct atttagaaaa tgttcagtta attctggatg aaattggctc
     4621 cctaaatcag gagttcgata gtcaggctta tcaggcagta cttgcgcgtg ttgtcgccat
     4681 ctctaaggag aaaaacggtc gtgctctgac taatgccagc cgtaaggctg atttgaagcc
     4741 cctggctgat gcctacaacg aagagagaaa gacccagttt actaaactag gacaattatc
     4801 agaccagata gcgattctcg actatcaaga acgttatcat ggagacactt ggaaactagc
     4861 taaaaccttc caatctttca tgagcgattt tgtagaggct tatcgtcaga gaaaacgaca
     4921 ggaaaatgcc tttgaattcg ctgatatcag ccattacacc attgagattt tagaaaattt
     4981 cccacaagtt cgtgagtctt atcaggagcg cttccatgaa gtcatggtcg atgagtatca
     5041 ggataccaac catattcaag aacggatgct ggaattgttg tctaatggcc acaatcgctt
     5101 tatggtggga gatatcaagc aatccatcta tcgtttccgt caggcagacc cgcagatttt
     5161 caatgagaaa ttccaacgct atgcgcaaaa tccccaagaa ggcaagctca ttctcctcaa
     5221 ggaaaatttc cgtagtagtt cagaagtgct gtcagcaacc aatgatgtct ttgaacgtct
     5281 catggaccaa gaggtcggcg aaatcaacta tgataacaag caccagcttg tttttgccaa
     5341 taccaaactg actcccaatc cagacaacaa ggcagaattt ctcctctacg acaaggacga
     5401 tacaggtgag gaagaagaga gtcaaacaga aacgaaacta acaggcgaaa tgcgcttagt
     5461 tatcaaggag attctgaaac ttcatcaaga aaaaggtgtt gcctttaagg aaattgccct
     5521 tctgacctcc agccgcagtc gtaatgacca gattctcctc gccctgtctg agtacgggat
     5581 tcctgtcaaa actgacggag agcaaaacaa ttatctccaa tccctagaag tgcaagtcat
     5641 gctagacact cttcgtgtca ttcacaatcc cctgcaagac tatgccttgg ttgcccttat
     5701 gaagtctcca atgtttggtt ttgatgagga tgagctagca cgtttgtccc ttcagaaagc
     5761 agaggataaa gtccacgaaa atctctatga gaaactggtc aatgcacaaa aaatggcaag
     5821 tagtcaaaaa ggcttgattc acacagctct agctgaaaaa ctaaagcaat tcatggatat
     5881 cctagcttct tggcgcttgt atgccaaaac ccactctctc tatgacttga tttggaagat
     5941 ttacaacgac cgtttttatt atgactatgt tggggctttg ccgaatggtc ctgctaggca
     6001 ggccaatctc tatgccctag cactgcgtgc tgatcaattt gaaaagagca atttcaaagg
     6061 tttgtcgcgt tttattcgta tgattgacca agtcttagaa gcccagcacg atttgtcaag
     6121 cgtggccgtc gcaccgccaa aagatgcagt agagctcatg accatccaca agagtaaagg
     6181 gctggagttt ccttacgtct ttatcctcaa tatggatcaa gatttcaaca agcaagactc
     6241 tatgtcagaa gtcattctca gtcgtcagaa tggtcttggt gtcaaatata ttgccaagat
     6301 ggagacaggg gcagtagaag accactatcc taaaaccatc aaactctcca ttcctagtct
     6361 gacctatagg cagaacgaag aggaattaca gctagcaagc tattctgagc agatgcgttt
     6421 gctgtatgtt gctatgacgc gggctgagaa aaagctctat cttgtcggca agggttctcg
     6481 tgaaaagctg gaagtcaagc aatacccagc agccaaaaat gggaaactaa atagcaatac
     6541 tagactgcaa gcacggaatt tccaagattg gctttgggct atcagtaaag tgtttactaa
     6601 ggacaagctc aactttagtt atcgttttat tggcgaagat cagttgacca gagaagctat
     6661 cggagagttg gaaaccaaga gtcctctcca agatagctcc caagcagaca atcgtcagtc
     6721 agataccatc aaagaagctc tggaaatgct gaaggaggtg gaagtttata atactcttca
     6781 ccgcgcagct attgaacttc ctagtgttca aaccccaagt caaatcaaga aattctacga
     6841 accagttatg gatatggaag gtgtcgagat tgctggtcaa ggtcagtcag taggcaagaa
     6901 aatcagcttc gatttgccag atttttcaac caaagaaaag gtaactggag ctgagattgg
     6961 tagtgctact cacgaactca tgcagagaat tgacctcagc cagcaactaa cccttgctag
     7021 cctaacagaa acactcaaac aagttcaaac tagccaagct gtcagagaca agatcaatct
     7081 tgataaaatt cttgctttct ttgacacagt actcggtcag gaaattcttg ctaataccga
     7141 ccatctctat cgcgagcaac ctttctccat gctcaaacga gaccaaaaga gtcaggaaga
     7201 ctttgttgtc cgtggtatcc ttgatggcta tctgctttac gaaaacaaaa ttgttctgtt
     7261 cgactacaag acagaccgct atgatgaacc aagtcaactc gtagaccgct atcgtggtca
     7321 gttagctcta tacgaagagg ctttatcacg agcctattcg attgaaaata ttgaaaaata
     7381 cttgatttta ctcggtaaag acgaggttca agttgtaaaa gtataactta tactctttga
     7441 aaatctcttc aaaccacgtc agcttcgcct tgctgt
//
LOCUS       DAVBOG010000073         7474 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.074, whole genome shotgun sequence.
ACCESSION   DAVBOG010000073 DAVBOG010000000
VERSION     DAVBOG010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7474
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.074"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            52..693
                     /locus_tag="VQ865_001971"
     CDS             52..693
                     /locus_tag="VQ865_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000234620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VIT family protein"
                     /protein_id="HET3136262.1"
                     /translation="MRAGVLGANDGIISIAGVVIGVASATTNIWIIFLSGFAAILAGA
                     FSMAGGEYVSVSTPKDTEEAAVSREKLLLDQDRELAKKSLDAAYIQNGECKTSAQLLT
                     NKIFLKNPLKALVEEKYGIEYEEFTNPWHAAISSFVAFFLRSLPPMLSVTIFPSDYRI
                     PATVLIVGVALLLTGYTSARLGKDPTRTAMIRNLAIGLLTMGVTFLLEQLFSI"
     gene            complement(735..2723)
                     /locus_tag="VQ865_001972"
     CDS             complement(735..2723)
                     /locus_tag="VQ865_001972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000489335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136263.1"
                     /translation="MFRLTNKLAVSNLIKNRKLYYPFALAVLLAVTITYLFYSLTFNP
                     KIAEIRGGTTIQATLGFGMFVVTLASAIIVLYANSFVMKNRSKELGIYGMLGLEKRHL
                     ISMTFKELVLFGILTVGAGIGIGALFDKLIFAFLLKLMKLKVELVATFQMKVVITVLL
                     VFGLIFLGLMFLNALRIARMNALQLSREKASGEKKGRFLPLQTILGSISLGIGYYLAL
                     TVKDPLTALTTFFIAVLLVIFGTYLLFNAGITVFLQILKKNKKYYYQPNNLISVSNLI
                     FRMKKNAVGLATIAILSTMVLVTMSAATSIFNSAESFKKVLNPHDFGVSGQNVEKEDL
                     DKLLSQFASDKGYKIKEKEVLRYTYFAVANQEGTKLTIFEKGQNRVQPKTVFMVFDQK
                     DYENMTGQKLSLSGNEVGLFAKNDGLKGQKALTLNDHQFSVKEEFNKDFIVNHVPNKF
                     NILTTDYNYLVVPDLQAFLDQFPDSAIYNQFYGGMNVDASEEEQLKVAEEYENYLNQF
                     NAQLDTEGSYVYGSNLADASSQMSALFGGVFFIGIFLSIIFMVGTVLVIYYKQISEGY
                     EDRERFIILQKVGLDQKQIKQTINKQVLTVFFLPLLFAFIHLAFAYHMLSLILKVIGV
                     LDTTMMLIVTLSICAIFLIAYVLIFMITSRSYRKIVQM"
     gene            complement(2725..3483)
                     /locus_tag="VQ865_001973"
     CDS             complement(2725..3483)
                     /locus_tag="VQ865_001973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000173375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136264.1"
                     /translation="MTLLDVKHVQKIYKTRFQGNQVEALKDIHFTVEKGDYVAIMGES
                     GSGKSTLLNILAMLDKPSRGQVYLNGTDTATIKNSQASSFRREKLGFVFQDFNLLDTL
                     SVKDNILLPLVLSRRPITEMMKKLVMTAENLGINQLQEKYPYEISGGQKQRVAVARAI
                     ITEPEILLADEPTGALDSKSSAALLDVFNEINERGQTILMVTHSTAAASRAKRVLFIK
                     DGILYNQIYRGEKTERQMFQEISDTLTVMASEVN"
     gene            3911..4102
                     /locus_tag="VQ865_001974"
     CDS             3911..4102
                     /locus_tag="VQ865_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000680763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136265.1"
                     /translation="MKHKEHILIGLLYLLSPFIGQLLVEHTHFIGTEFTGTAYVICWL
                     SVVISIHHFSKNVLSQQQK"
     gene            complement(4456..4728)
                     /locus_tag="VQ865_001975"
     CDS             complement(4456..4728)
                     /locus_tag="VQ865_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HET3136266.1"
                     /translation="MNSKFYKMRRNRMISGVLAGLSDKWNFDVTLVRFLFAIFTVANF
                     GLGVIIYIILASIMPTKEEIEAEMYGTGPRKRKEAQAIDDNEGWFW"
     gene            complement(4787..5236)
                     /locus_tag="VQ865_001976"
     CDS             complement(4787..5236)
                     /locus_tag="VQ865_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000778579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HET3136267.1"
                     /translation="MKLTDYVKQVSLEDFGRAFIHHVQWNRRLRSTGGRFFPKDGHLD
                     FNPKVYQKLGMEVFRKIVRHELCHYHLYFQGKGYQHKDRDFKELLKAVDGLRFVPSLP
                     NSNSKPLKLYRCQSCQQRYQRKRRIDTQRYRCGLCRGKLLLINQPED"
     gene            complement(5223..7352)
                     /locus_tag="VQ865_001977"
     CDS             complement(5223..7352)
                     /locus_tag="VQ865_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000359105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HET3136268.1"
                     /translation="MDKKYEKISQDLGVTLKQIDTVLSLTAEGATIPFIARYRKDMTG
                     SLDEVAIKAIIDLDKSLTNLNDRKEAVLAKIQEQGKLTKELEEAILVAEKLADVEELY
                     LPYKEKRRTKATIAREAGLFPLARLILQNIVDLEKEAEKFVCEGFATGKEALTGAVDI
                     LVEALSEDVTLRSMTYQEVLRHSKLTSQAKDESLDEKQVFQIYYDFSETVGTMQGYRT
                     LALNRGEKLGVLKIGFEHATDRILAFFATRFKVKNAYIDEVVQQSVKKKVLPAIERRI
                     RTELTEKAEEGAIQLFSDNLRNLLLVAPLKGRVVLGFDPAFRTGAKLAVVDATGKMLT
                     TQVIYPVKPASARQIEEAKKDLADLIGQYGVEIIAIGNGTASRESEAFVAEVLKDFPE
                     VSYVIVNESGASVYSASELARQEFPDLTVEKRSAISIARRLQDPLAELVKIDPKSIGV
                     GQYQHDVSQKKLSESLDFVVDTVVNQVGVNVNTASPALLSHVAGLNKTISENIVKYRE
                     EEGKITSRAQIKKVPRLGAKAFEQAAGFLRIPESSNILDNTGVHPENYTAVKELFKRL
                     DIKDLNEEAQSKLKSLSVKEMAQELDLGPETLKDIIADLLKPGRDFRDSFDAPVLRQD
                     VLDIKDLVVGQKLEGVVRNVVDFGAFVDIGIHEDGLIHISHMSRKFIKHPSQVVSVGD
                     LVTVWVKKIDTEREKVNLSLLAPNETD"
BASE COUNT         2210 a         1562 c         1472 g         2230 t
ORIGIN      
        1 tcagaaacaa atcacgaaat cgattcaaat tttgcaggtc gtttaaatat cctgcgcgca
       61 ggtgttcttg gtgctaacga tggaattatt tccattgctg gtgtggttat cggggttgcc
      121 agtgccacga ccaatatctg gattatcttt ttatcaggat ttgcggctat cttagctggt
      181 gccttttcaa tggctggtgg agaatatgta tccgtttcaa ctccaaaaga taccgaggaa
      241 gctgccgttt cgcgagaaaa actcttgtta gaccaagata gggaactagc caaaaaatcc
      301 ctcgatgctg cttatatcca aaatggagaa tgcaaaactt ctgcccaact cttgaccaat
      361 aagatctttc ttaaaaatcc actcaaggct ctggtagagg aaaaatatgg gattgagtat
      421 gaagaattta ccaatccttg gcacgctgcc atttctagct tcgttgcctt tttccttaga
      481 agtttgcctc caatgctgtc agtgaccatt tttccaagtg attaccgcat ccctgctact
      541 gtccttattg tcggtgtggc ccttcttctc actggttaca ctagtgccag acttggaaag
      601 gatccgacta gaacagctat gattcggaac cttgctattg gtctcttgac catgggagtt
      661 accttcctgc tcgaacaact tttcagcatt tagaatacaa gaaatacctc gattttgaag
      721 tcgaggtatc ttttttacat ttgcacaatc ttgcgataac ttcttgaagt aatcatgaaa
      781 atcagcacat aggcgatgag gaagatagcg cagatagaca aggtcacaat caacatcata
      841 gtcgtatcca gtacaccaat cacttttaaa atcaggctaa gcatatggta ggcaaaggcg
      901 agatgtatga aggcaaagag caaaggaagg aagaaaacag ttaaaacctg tttgttgatg
      961 gtttgcttga tttgcttttg gtccaaacca actttctgca agataataaa gcgttcacgg
     1021 tcttcgtagc cttcagaaat ttgtttgtag tagatgacca gaacagttcc gaccataaag
     1081 ataatggata ggaaaatacc gataaagaag acaccaccaa agagggcact catctgagaa
     1141 ctagcatctg ctagattgct accataaaca tagctacctt ctgtgtctaa ttgagcatta
     1201 aattgattga ggtagttttc atactcctca gcgaccttga gttgttcttc ttcgctggca
     1261 tctacattca taccaccgta aaactgatta tagatagccg aatctgggaa ttgatccaaa
     1321 aaggcttgta aatcaggaac aacaaggtaa ttgtaatcag tagtcaagat attaaactta
     1381 tttggaacat ggttcacaat gaaatcttta ttaaattctt ctttgacaga aaattgatga
     1441 tcatttagag ttagagcttt ctgtcctttc agtccgtcat ttttggcaaa gagaccgacc
     1501 tcatttcctg atagagacag tttttgacca gtcatatttt cataatcttt ttggtcaaat
     1561 accatgaaaa ctgtttttgg ttggacacgg ttttgtcctt tttcaaaaat agttaacttg
     1621 gttccttctt gattcgcaac agcaaagtaa gtgtaacgaa gcacttcttt ctctttaatc
     1681 ttataacctt tgtcacttgc aaactggctc aagagtttgt ccaaatcttc tttttcaaca
     1741 ttttgccctg aaaccccaaa atcatgagga tttagaactt ttttaaagga ttctgcggaa
     1801 ttgaaaatgc ttgtcgctgc tgacatggtt accaaaacca ttgttgacaa aatagcgata
     1861 gttgctagtc caactgcatt tttcttcata cggaaaatca agttagaaac agatatgaga
     1921 ttattaggtt ggtaatagta tttcttattt ttctttaaga tttgaaggaa aacggtaatc
     1981 cctgcattga acaaaagata agtaccaaag ataaccagta aaacagctat gaagaaggtt
     2041 gttaaggctg taagaggatc ttttaccgta agggcaagat aatatccaat ccctaaactt
     2101 atggaaccaa gaatagtttg gagaggaagg aagcgacctt ttttctctcc gctagctttc
     2161 tcacgtgaga gctggagggc attcatacgg gcgattcgaa gggcattcag gaacatgagg
     2221 cctaggaaaa tcaaaccgaa gacaagaagt actgtaatga caactttcat ctggaaggta
     2281 gcgaccagtt ccaccttcaa tttcatcagt ttgagtagga aagcgaaaat caacttgtca
     2341 aacaaggctc caataccgat tcctgctcca acagttagaa tcccaaatag cactaactcc
     2401 ttaaaggtca tactgattag atggcgcttc tccaagccta acatgccata tatacccagt
     2461 tccttggaac ggtttttcat gacaaaacta ttggcataga ggacgataat ggctgacgca
     2521 agggtaacga caaacatacc aaatccaagt gttgcttgaa tggtggttcc tccacggatt
     2581 tccgcaatct ttggattgaa ggttagggag taaaagagat aggtgatggt gactgccaag
     2641 agaacagcca gtgcaaaggg atagtagagt ttgcggtttt taatcaagtt cgataccgct
     2701 aacttattgg ttaatcgaaa catactaatt cacctcgctt gccatgacag tcaaggtatc
     2761 agagatttct tggaacatct gacgttctgt cttctctcca cggtagattt gattgtaaag
     2821 aatgccgtct ttgataaaga gaacacgctt ggccctgcta gcagctgctg ttgagtgggt
     2881 taccatgagg atggtttgcc cacgctcatt gatttcatta aagacatcaa gtaaggctgc
     2941 agatgacttg gaatcaaggg ctcctgttgg ctcgtccgca aggagaattt caggttctgt
     3001 gatgatggcg cgggctactg ctacacgctg tttctgacca ccagaaatct cgtaagggta
     3061 cttctcttgc aattggttga tacccagatt ttcagctgtc atcaccaatt tcttcatcat
     3121 ctccgttata ggtcttcttg acaagacaag cggaagcaag atattgtcct taacagacag
     3181 agtatctagc aagttaaagt cttggaagac aaatcctagc ttttcacgcc ggaaactaga
     3241 agcctgtgaa tttttaatag ttgctgtatc agttccgttt aggtaaacct gcccacgact
     3301 tggtttatcc agcatagcta ggatattgag cagagtggat ttaccagaac cagactcacc
     3361 catgatagca acgtagtcac ccttttctac ggtgaagtga atatccttga gggcctctac
     3421 ttggttgccc tgaaaacgtg ttttataaat tttttgaacg tgttttacat ctaaaagtgt
     3481 catgagaatc tcctttctta atatcccatc aaatgaaatg tagcttgcat catagtgcat
     3541 cccagctgaa cgcgctcaat ttctttgtga cttggttttc tagttttctt atgtaagatt
     3601 tgtttcatga tgttactcct ttgttcttta tgagtctagt ttacatcaaa aaaagaccgc
     3661 ttgccataac ctaaccttac aaaagagact ttaatcttac atttttgtaa gattgggtga
     3721 aatataagca aaattactta gaaaatgatt tgatttccta tttttaaagt tgtaaaatat
     3781 aagtgtgaaa aggcttactt tgaaaaggag gaagcgggaa ctaacatttt agtaaggtta
     3841 cctagataac ataccattca atttaacact tgcaagtcgt tcaacctata aggaaagaag
     3901 gtgcgcttta atgaaacaca aagaacatat actcatcgga cttctctatc tgctctctcc
     3961 attcatcggt cagctcttag ttgaacacac acactttatc ggtacagaat ttaccggcac
     4021 tgcttatgtt atttgctggt tatcagttgt tatcagcatc caccattttt ccaaaaatgt
     4081 attgtctcag cagcaaaaat agattaaaaa actgagttta aattactgct tttataataa
     4141 aatgaaataa gaacaggaca aatcgatcag gatagtcaaa tcgatttcta acaatgtttt
     4201 agaagtagag gtgtactatt ctagttccaa tccactatag tttgtggatg aagctggcga
     4261 aatattatta atactattca aaaatcaaag tgcaaactat gtcaacttca cattgccgac
     4321 taaattacag cctgtggctg gcttcctagt ttgcactttg atttttattg agtataaaag
     4381 taaaaaagct ttaaatcaag cagtttagac tattgattta aagatttttg cttattccaa
     4441 atcttctgta gaacctcacc aaaaccagcc ttcattgtcg tcaatggctt gggcttcttt
     4501 gcgtttacgt gggcctgttc cgtacatttc tgcttcgatt tcttccttgg taggcatgat
     4561 agaagctagg atgatataga taatcacgcc aagtccaaag tttgcaactg taaaaatggc
     4621 aaacaagaaa cgaactaggg taacatcaaa attccacttg tctgacagac ctgccagaac
     4681 tcctgaaatc atgcgattgc gtctcatttt ataaaattta ctgttcatga tatttcctct
     4741 ttctgctagg ttagacatag tatatcacgg ggaggctcgg ctttcatcag tcctcaggct
     4801 gatttatcag aagcaattta cctcgacaaa gtccacagcg atagcgttgg gtatcaatcc
     4861 tacgcttgcg ctgatacctt tgctggcagg attgacaacg ataaagcttg agtggtttag
     4921 agttactatt gggcaaggat ggtacaaacc ttaatccatc cactgctttc aaaagttcct
     4981 taaaatcccg atccttgtgt tgatagccct tcccttggaa ataaaggtga taatgacaga
     5041 gttcatgtcg gacaattttc ctaaaaacct ccatacccag tttctgataa accttgggat
     5101 taaaatccag atgcccatct ttggggaaaa atcgcccacc tgtcgaacgt agacgcctat
     5161 tccactggac atgatggata aaagctctcc cgaagtcttc tagtgaaacc tgcttgacat
     5221 aatcagtcag tttcatttgg agcgaggagc gacagattaa ctttttcacg ttcagtatca
     5281 attttcttga cccaaacggt caccaaatct ccaactgaca ccacttgact agggtgtttg
     5341 ataaacttgc gactcatatg agaaatatga atcaagccgt cctcgtgaat cccgatatca
     5401 acgaaggcac cgaagtcaac aacgttacgc acaacacctt ctagcttctg acctaccact
     5461 aggtctttga tatctaggac atcttggcga agcacaggtg cgtcaaagga atcacggaaa
     5521 tctcgacctg gtttgagaag atctgcaatg atatctttaa gggtttctgg accgaggtct
     5581 agctcttgag ccatttcctt gactgaaagg gacttgagtt tgctttgggc ttcttcgttt
     5641 aggtctttaa tatctaaacg tttgaagagt tccttaactg cagtgtaatt ctctgggtga
     5701 actcctgtat tatcaaggat attgctactt tcagggatac gaaggaaacc agcagcctgc
     5761 tcaaaggcct tggctcccag acgaggaact ttcttgattt gggcgcgtga agtgattttt
     5821 ccttcttcct cgcggtattt gacaatattt tcagagatag ttttgttgag tccagctacg
     5881 tgtgaaagaa gagctgggct agctgtattg acattgacac caacttggtt aaccactgta
     5941 tcgacaacaa agtccagact ctcagatagt ttcttctgac tgacatcgtg ttggtattga
     6001 ccgacaccaa ttgacttagg atcgattttg accaattccg caagaggatc ttgcaaacga
     6061 cgggcgatag aaatggcaga gcgtttttca acggtcaagt ctggaaactc ctgacgagca
     6121 agttcgctgg cagaatagac agaagcacca ctttcattaa cgataacata gctgacttca
     6181 gggaaatctt tcagaacttc cgctacaaaa gcttcacttt cacgactggc cgttccattt
     6241 ccaatggcaa taatctctac accgtattga ccaattaaat ctgctaaatc tttcttggct
     6301 tcttcgattt gacgagctga tgctggttta acaggataaa taacctgagt tgtcagcatt
     6361 tttcctgttg catccacgac agctaacttg gcacctgtac gaaaggctgg gtcaaatcca
     6421 agaaccacgc gccctttcag tggagcaacc aagaggagat tgcgcagatt gtcagaaaaa
     6481 agttggatag ctccttcttc agctttctca gttaattctg tccgaatacg acgctcgata
     6541 gcaggcaaga cctttttctt aacggattgc tgaacaactt catcaatata agcatttttc
     6601 accttgaaac gagtagcaaa gaaggcaaga atacggtccg tcgcatgttc aaaaccgatc
     6661 ttcaagacac caagtttctc cccacgattg agagccaagg tacgatagcc ttgcatagtt
     6721 ccaactgtct ctgaaaaatc ataataaatc tgaaaaacct gcttttcatc aagactttca
     6781 tccttggctt gagaagtgag tttagagtgt ctcagcactt cctgataagt catagaacgc
     6841 aaggtcacat cttccgataa ggcttcgacc aaaatatcaa ctgcaccggt caaggcttcc
     6901 ttgccagtcg caaatccttc acagacgaac ttttcagctt ctttctctaa gtcaactata
     6961 ttctgcaaaa tcaagcgagc aagaggaaag agtccagctt cacgggcaat ggttgccttg
     7021 gtacgacgct tttccttata aggaagatag agttcttcaa cgtctgctaa tttttcggca
     7081 actaagatag cttcttccaa ttccttggtc aacttacctt gttcttgaat cttagctaag
     7141 acagcttcct tacggtcatt gagatttgtc agacttttat ccaaatcaat aatagcctta
     7201 atcgccacct catccagact accagtcatg tccttgcgat aacgcgcgat aaagggaata
     7261 gtcgcccctt cagctgtcaa acttagaacg gtatcaattt gctttaacgt cactcccaaa
     7321 tcctgagaga ttttttcata ttttttatcc ataaatctat tataccacaa gctggaaggc
     7381 tttctccaat ccttttcata ctcaataaaa atcaaaaagc aaactaggaa gctagccgta
     7441 ggctgctcaa aatactgttt tgaggttgtg gata
//
LOCUS       DAVBOG010000074         7451 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.075, whole genome shotgun sequence.
ACCESSION   DAVBOG010000074 DAVBOG010000000
VERSION     DAVBOG010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7451
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.075"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(173..1588)
                     /locus_tag="VQ865_001978"
     CDS             complement(173..1588)
                     /locus_tag="VQ865_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000151865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HET3136269.1"
                     /translation="MTIFPDDFLWGGAVAANQVEGAYNEDGKGLSVQDVLPKGGLGEA
                     TENPTEDNLKLIGIDFYHKYKEDISLFSEMGFNVFRTSIAWSRIFPKGDEEEPNEAGL
                     KYYDELFDELHAHGIEPLVTLSHYETPLYLARKYHGWIDRRMIHFYEKFARTVLERYK
                     DKVKYWLTFNEVNSVLELPFTSGGIDIPKENLSKQELYQAIHHELVASSLVTKIAREI
                     NSEFKVGCMVLAMPAYPMTPNPKDVWATHEYENLNYLFSDVHVRGYYPNYAKRYFKEN
                     DINIEFAAEDAELLKNYTVDFLSFSYYMSVTQSALPTQYNSGEGNIIGGLVNPYLESS
                     EWGWQIDPIGLRIILNRYYDRYQIPLFIVENGLGAKDQLIKDEFNNLTVQDDYRIQYM
                     KEHLLQVAEALQDGVEIMGYTSWGCIDCVSMSTAQLSKRYGLIYVDRNDDGNGTFNRY
                     KKMSFTWYKGVIESNGESLFK"
     gene            complement(1601..3439)
                     /locus_tag="VQ865_001979"
     CDS             complement(1601..3439)
                     /locus_tag="VQ865_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HET3136270.1"
                     /translation="MSYKDKVQKILDVIGGEKNVNRVTHCVTRLRLELKDENLVNDDD
                     VKKIPGVIGIMKKNGQYQIILGNDVANYYKEFVKLGNFESDSVVQGHKGNILERIIEY
                     IAGSMTPIIPAMLGGGMLKVLVIILPMLGILQSDSQTIAFLTFFGDAPYYFLPLLLAY
                     SASQKLKVTSTLAMSVAGVLLHPNFVQMVQSGNPLSLFGVPVIPASYGSSVVPILIMV
                     WLMKYIEKMIAKLTPAVTKSFLQPTLVLLVSSCIALVVVGPIGVIVGEGLSNLVGQMY
                     DVAGWLTLAILGAIMPFIVMTGMHWAFAPIFLAASIATPDVLILPAMLGSNLAQGAAS
                     MAVALKSKNNNTKQIAFAAGFSALLAGITEPALYGVTLKYKKPLYAAMIGGGLAGLFA
                     GLTSVKAYLFAVPSLIALPQFIYSDVPSNIVNALIVAVISVVITFVLAYIFGIDEEES
                     SSNLEVKAGVSNKKMIFSPISGEIIPLSDVQDKTFSDKLIGDGVAIIPSEGKVYAPFD
                     GKITNIFPTKHAIGLKSDEGVELLIHIGLDTVELKGQGFISHVEEGDRVFKNQLIFEM
                     DLNLIKTKGYETVTPVIVTNTNDFLDVLVLPNNQTIEHSKELLVIL"
     gene            complement(3457..4296)
                     /locus_tag="VQ865_001980"
     CDS             complement(3457..4296)
                     /locus_tag="VQ865_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006270038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HET3136271.1"
                     /translation="MIIKRILNHNAVIAQSKKDIDILLFGRGIAFGRKTGDKVNPIDI
                     EKSFFLKNRDNMTRFTEMFINVPLELVYITEKIINLGKITLGNNFDEIIYINLTDHIS
                     SSIERYKEGVIISNPLRWEISKYYKEEFELGKRALQIIKKELGIELPIDEAAFIALHF
                     VNANLENNFQESYKITEIIMGIEKIIQDFYCTEFNQDSIDYYRFITHIKLFAHRLVEN
                     TTYCDDDDEDLLALMKNKYPREYECGEQVAMFIQTEYNYLLTSSELVYLMAHIRRLTK
                     NLD"
     gene            complement(4597..7276)
                     /locus_tag="VQ865_001981"
                     /pseudo
     CDS             complement(4597..7276)
                     /locus_tag="VQ865_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268095.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
BASE COUNT         2443 a         1568 c         1026 g         2414 t
ORIGIN      
        1 ccaatctatc ctaagttaac tatttataat cggctctctg taacaaaatt aaattaatta
       61 atccccctat aaaataaaga ggtttagaat ttgatgtctt ccaaacctct ttatttcata
      121 tttaatgaga tgctgcctta accgtgataa tatctaatca tcaataaaca aactatttga
      181 ataaggattc tccatttgat tcaatcactc ctttatacca agtaaaggac attttcttat
      241 atcgattgaa tgtgccattt ccatcatcat ttcgatcaac ataaatgaga ccgtacctct
      301 tagaaagctg tgcagtggac atagaaacgc agtcaataca tccccaagac gtatagccca
      361 taatttccac accatcttgt agagcttcag ctacttgcaa taaatgttct ttcatatact
      421 gaattctata atcatcttgg actgttaagt tattaaattc atcttttatt agttgatctt
      481 tagcacctaa tccgttttcc actataaata atggaatttg ataacggtca taatatctat
      541 ttaaaattat acgtagtcca attggatcaa tttgccatcc ccactcagaa gactctaaat
      601 aaggatttac taaaccacca ataatattcc cttctcctga attatactgt gttggaagag
      661 cagattgagt cacactcatg taatagctaa aggataaaaa atctacagta taatttttta
      721 ataactctgc atcttcagct gcaaactcta tgttaatgtc attttcctta aaatatcttt
      781 ttgcataatt cggataataa cctctaacat gcacatctga aaatagataa tttagattct
      841 catactcatg agtcgcccat acatcttttg gatttggagt cattggataa gctggcatag
      901 ctaataccat acaccccacc ttaaactctg aattaatctc acgagcaatt tttgtaacca
      961 aactcgaggc gactaattca tgatgtatag cttgatataa ttcttgtttc gaaagattct
     1021 ccttaggtat atctattcct ccactagtaa acggtaattc caaaacagag tttacttcgt
     1081 taaatgtaag ccaatattta actttatctt tatacctttc taaaactgtt cgagcaaatt
     1141 tttcataaaa atgaatcatt ctcctatcaa tccatccatg atattttctt gctaaatata
     1201 atggagtctc atagtgtgaa agagttacaa gtggttctat cccgtgagca tgtagttcat
     1261 caaacaattc atcataatat ttcaacccag cttcgttagg ttcttcctca tctccttttg
     1321 gaaaaattct actccatgca atagaagtac gaaaaacatt aaagcccatt tcagaaaaca
     1381 aggatatatc ttccttatat ttatgataaa aatcaatacc tatcaatttt aagttatctt
     1441 ctgtaggatt ttctgttgct tctcctaatc cacctttggg taacacatcc tgaactgata
     1501 agcccttacc atcttcatta tatgctccct ctacttgatt agctgcaaca gctccacccc
     1561 aaagaaaatc atctggaaaa atggtcataa ctttcctcca ttataatatt accagtaatt
     1621 ccttagaatg ctcgattgtc tgattattag gtaatactaa tacatctaga aaatcattgg
     1681 tattcgttac aattactggt gtaactgttt cgtagccttt agtcttgatt aaattcaagt
     1741 ccatttcaaa aatcaactga tttttgaaaa ctctgtctcc ttcttctaca tgactaataa
     1801 aaccttgacc ttttagctca acagtatcta atccaatatg aattagtaac tcaacaccct
     1861 catcactctt caatccaatt gcgtgcttag tcggaaaaat atttgtaatt ttcccatcaa
     1921 atggtgcata aaccttacct tcacttggaa taatcgctac tccgtctcca attagtttat
     1981 ctgaaaatgt tttatcctgg acatcgctta acggaatgat ttctcctgat ataggagaaa
     2041 atatcatttt tttatttgaa actccagctt taacttctaa attgctagaa ctctcttctt
     2101 catcgattcc aaatatataa gctaatacaa aggtaataac aaccgaaata accgccacaa
     2161 ttaaagcatt tacaatattt gatggtacat cagaataaat aaattgaggc aacgctatca
     2221 aagatgggac agcaaataga tacgctttaa cactagtaag acctgcaaat aatcccgcta
     2281 atccaccacc aatcatagct gcataaagcg gttttttata ttttaaagtc acaccatata
     2341 atgcaggttc ggtaatccct gcaagtaagg ctgagaaacc tgctgcaaaa gcaatttgtt
     2401 ttgtattatt atttttactc tttaatgcaa cagccatcga agcagcccct tgagctaagt
     2461 ttgaccctaa cattgctgga agaattaata cgtctggagt agcaatagat gccgccaaaa
     2521 aaataggtgc aaaagcccaa tgcattccag tcataacaat aaatggcata atagcaccaa
     2581 gaatagctaa tgtaagccat ccagctacat catacatttg cccaactaga tttgataatc
     2641 cttcaccaac aattactcca ataggcccga ctacaactaa ggcaatacag cttgatacta
     2701 ataatactag cgtaggttgc aaaaaactct tagtaacagc tggtgttaat ttagcaatca
     2761 ttttttcaat atatttcatc aaccaaacca taataagaat tggaacgact gacgaaccat
     2821 aactagctgg tatcacaggt acaccaaata aactaagagg attccctgat tgcaccattt
     2881 gaacaaaatt tggatggaga agtacacctg ctacagacat agctaatgta gatgttactt
     2941 ttaatttttg tgatgcagaa taagctaata acagcggtaa gaaataatat ggagcatccc
     3001 caaaaaatgt caaaaaagca atagtctgag aatctgattg caatatacca agcattggta
     3061 aaataattac caagactttc agcatacctc cccctaacat tgctggaatg attggagtca
     3121 tggaaccagc gatatactca atgattcttt ctaaaatatt ccctttgtgc ccttgaacaa
     3181 ctgaatcgga ttcaaaattg ccaagtttaa cgaattcttt ataataatta gctacatcat
     3241 taccaagtat aatttgatat tgtccattct ttttcataat acctattaca cctggtatct
     3301 tcttcacatc atcatcattg actaaatttt catcttttaa ttctaatctt aaacgtgtta
     3361 cacaatgggt aactctattg acattttttt cacctccaat tacatcgagg attttttgta
     3421 ccttatcttt ataactcatg gtattctcct attctattaa tctaaatttt ttgttaagcg
     3481 acgaatatga gccatcaaat aaactaattc actagaagtc agcaaataat tgtactcagt
     3541 ttgtataaac attgccacct gttcaccaca ttcatattct ctaggatatt tatttttcat
     3601 taatgctaac aagtcttcat catcatcgtc acaataagtt gtattttcaa ccaagcgatg
     3661 ggcaaataat tttatatgag ttatgaatct ataataatca atagaatctt ggttaaactc
     3721 agtacaatag aaatcttgaa tgattttctc aattcccata attatttcag tgattttata
     3781 cgactcttga aaattatttt ctaaattagc attaacaaaa tgtagcgcta tgaatgcagc
     3841 ttcgtcaatt ggaagttcaa tacctaactc tttttttatt atttgtaaag cccttttccc
     3901 aagctcaaat tcttctttat aatatttcga gatttcccag cgtaggggat tcgaaataat
     3961 aactccttct ttataacgtt ctatactcga agaaatatga tccgttagat ttatatagat
     4021 aatctcatca aaattattac ctaatgttat tttacctagg ttaattattt tttcggtgat
     4081 gtacaccaac tccaaaggaa cgttaataaa catctctgta aaacgggtca tattatctct
     4141 atttttgaga aaaaaacttt tctcaatatc aattggattt actttatctc cagtttttct
     4201 tccaaaagct attccccttc caaaaagaag aatatcgata tcttttttac tttgcgcaat
     4261 tacggcattg tggtttagta ttcgttttat gatcataaaa tttccctttt aaaataaaag
     4321 gaacctactt aaaaaacatc aagaaacttc ttctgatgtg attaaatagg ttcctgctca
     4381 cttgtattag tgataacatc cttttatttc aatttttaat ggtgacatga agcttaaata
     4441 attaataact ctgtaaccgt ttttatttta tgatatttca atctatttgt caagtactta
     4501 taaaaatttt tttattttgt gtgattcgaa tgtgataatg gcaacagtct cactaaagaa
     4561 atgaaaatca tacatagaaa tttttaaaaa ttttctctat cgtaaacctg ccactagttc
     4621 agaaactata ctagctgatt ccaaacgtaa tatggtcatc tcatctacct tccctaataa
     4681 tggcattgca ccataccaaa caatagtctt attcaccaaa agaataggcg ttactatttt
     4741 tgattgagta aaagacactt taattttctg gctcttcaac tggtctagcc atgctttatt
     4801 tgcaaccgtc tctggtatac atatctcaat ttgactaatc ctaaattctt ttagaaaatt
     4861 catcagtttt gtctggtgca cataaggtaa aataagcaga cattcctgtc tttcccctgc
     4921 taagtcctct ctcaacacct tctcatatct actatcaaca taaacgaatt gtttctcctc
     4981 accctcgatg acacgataat ccatctttcg ataagctact tgtcgtttct gaaacatctt
     5041 ttctaaataa ggaacatgaa tatccacata atcgaaaata cgcaccaaag acttatcctt
     5101 gtagtttcta tgaatccgac ctgcatactg aattaaatta tttttccaag aaaagggtgc
     5161 tgccaagata agcgtgtcca actgaggtaa gtcaaaacct tcgccaatgt attttccagt
     5221 agacaacaaa acaaaccctt tatctaactg ttctaacgtc tccagtaaac tcgttctttc
     5281 tcggactttg gtttttccgc taataatgta acagtcatca acctctttct ctttcaataa
     5341 cttttcaaag acatctatct gttgaattcg attaactaaa accaagatat tccgtccttc
     5401 tgccacttgg gctagaatat ccttgagaat caactgattc ctcgctgagt ctgtagcaat
     5461 ccaatcactg agctgtataa aattacttgc tttggtcttt tcaatctcca aatgaccaaa
     5521 agaagtgaat cttaattgca attgccgttt aaaatccgtt tccctcttat cagcagtatg
     5581 gagtatctca ccaattctct gaaaaacaat aggctcatga ccattcttac gctcaggcgt
     5641 agccgtcaaa ccgtaaagat acttccctct aaactgagca acaacttttt caaacatcaa
     5701 ggcagagaca tgatgacact catccacaat catcatctca tactcatcca aaagactttg
     5761 actattttcc aacttaaata gagattgaat cataacgaca tcaaccagtt tactcagcca
     5821 tttcttagtc ccaccgtact gtccaacata gccgattacc ttttcacgac ctgatgccgt
     5881 ataacggata gcctcctcct cttcgaaagt caaaaagcag tttaagcgat ctagccattg
     5941 gtctaagagt tgcttattat ggactagaat aattgttttt gttttccgtt cagagataag
     6001 agcagcacct aaaacggtct tcccaaaacc agtctccgca tgaagtaaac cattttcttt
     6061 agaagtcata tctgacaggg ctaactcttg ctcaaaagtg agttctccct taaattccac
     6121 gctaatagac ctttgtacct ttctcctatc ttccacagat acctgcttaa atttatcttg
     6181 caatggatat aacaagcctc ttggcagcca taaataataa tcggattctc caaataaata
     6241 cattctctca ggaatttgat aggttggctg tcgcatagcc tgctttaaat aaaattcggg
     6301 attagaaaat gaagccatat ttttcaagaa aaacagtgtc ttgggtgtca cagacgattt
     6361 ttcaagttgg atcatattgg ataagacgat cttcaactcc ttgtccaatt cttgcttgcc
     6421 taactcttct tggattaaca gtgccacttt agcagttgaa accctctgaa tttcttgtag
     6481 atacctccat tggtcttcat aaggctgaaa ctgttcatcc acaaagaccg ttcgcccttg
     6541 atggtaagct tctccttgaa aaggcaaggc aatcaaattt ccaaatcccc cccttaggaa
     6601 ggacatcctg atttggaaac atgcgatcaa aagaatcaaa ggacagttgc atactttcct
     6661 gcattgccag ttctatcagt ttctttccaa acaagcgagc ctctcgactc ggaatcgctt
     6721 cctcaaagaa gaaccaaata tggagtccgt gacccgaacg agaaatctct aaatgggctt
     6781 ccatctggcg ttccctggct attcttcgaa tggttaaacc agcttctttc caatctcctt
     6841 catcaaaatc cagtaccaaa aaatgacagc tatcatctaa gtgcatagga aagataccga
     6901 tagctgtctc cccacgaaaa tgagatttca aaacggagtc cgtcaatgtc tggaaactcc
     6961 gtttttcaag tggcaactgc ttccaaccat aatcatagga aggaaaatac tgaattttcc
     7021 cttgatcatt gataaaactc ttagcataaa catcataacg gccagcaaac acggaggtaa
     7081 acaattgtaa tttttcttgc gtcgtcaagt gactactttg aagttggaac atctcctcga
     7141 accgagagcg ttccatcaca aactgactct tgtctttaag acgtttacac aagaaaaact
     7201 cactatcccc attaaaagaa gaaaagacat caagtacttc taccacaatt ccatccaaag
     7261 acacaaaaat agccataaca atcacctcct tgattcctat aggctgatta taacaagaat
     7321 ggctgaaatt gtacacgaaa ataaaatccg aatagcactc attttgtatg cgactaatag
     7381 tccatctcgc tccggaatgt acgaagtaaa tagagtttaa acgagcagtc tataaaattc
     7441 aaaaaacgca t
//
LOCUS       DAVBOG010000075         7292 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.076, whole genome shotgun sequence.
ACCESSION   DAVBOG010000075 DAVBOG010000000
VERSION     DAVBOG010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 7292)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7292)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7292
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.076"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(112..387)
                     /locus_tag="VQ865_001982"
     CDS             complement(112..387)
                     /locus_tag="VQ865_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HET3136272.1"
                     /translation="MANKQDLIAKVAEATELTKKDSAAAVEAVFAAVADYLAAGEKVQ
                     LIGFGNFEVRERAERKGRNPQTGKEMTIAASKVPAFKAGKALKDAVK"
     gene            complement(494..1333)
                     /locus_tag="VQ865_001983"
     CDS             complement(494..1333)
                     /locus_tag="VQ865_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000161411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HET3136273.1"
                     /translation="MTKIKIVTDSSVTIEPELVKQLDITIVPLSVMIDNVVYSDADLK
                     EEGKFLQLMQESKNLPKTSQPPVGVFAEIFEDLCKDGGQILAIHMSHALSGTVEAARQ
                     GASLSTADVTVVDSSFTDQALKFQVVEAAKLAQEGKDMEAILCHVEEVKNHTELYIGV
                     STLENLVKGGRISRVTGLLSSLLNIRVVMQMKDHELQPMVKGRGTKTFKKWLDELITS
                     LSERAVAEIGISYSGSDDWAKEMKESLQAYVEKPISVLETGSIIQTHTGENAWAILIR
                     YHS"
     gene            1475..2323
                     /locus_tag="VQ865_001984"
     CDS             1475..2323
                     /locus_tag="VQ865_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3136274.1"
                     /translation="MIKKIYPIFTILLGAAIYAFGLTYFVVPHHLFEGGATGITLITF
                     YLFKIPVSLMNLLINIPLFILAWKIFGAKSLYSSLLGTLALSGWLAFFEHIPLHIDLQ
                     GDLLITALIAGILLGIGLGIIFNAGGTTGGTDILARILNKYTHISIGKLLFILDFCIL
                     MLILLIFKDLRLVSYTLLFDFIVSRVIDLIGEGGYAGKGFMIITKRPDQLAKAINDDL
                     GRGVTFISGQGYYSKENLKIIYCIVGRNEIVKTKEMIHRIDPQAFITITEAHEILGEG
                     FTFEKE"
     gene            complement(2416..3333)
                     /locus_tag="VQ865_001985"
     CDS             complement(2416..3333)
                     /locus_tag="VQ865_001985"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000587449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HET3136275.1"
                     /translation="MIITIPIKNQKDIGTPSDSVVVLGYFDGIHKGHQELFRVANKAA
                     RKDLLPIVVMTFNESPKIALEPYHPDLFLHILNPAERERKLKREGVEELYLLDFSSQF
                     ASLTAQEFFATYIKAMNAKIIVAGFDYTFGSDKKTAEDLKDYFDGEVIIVPPVEDEKG
                     KISSTRIRQAILDGNVKEAGKLLGAPLPSRGMVVHGNARGRIIGYPTANLVLLDRTYM
                     PADGVYVVDVEIQRQKYRAMASVGKNVTFDGEEARFEVNIFDFNQDIYGETVMVYWLD
                     RIRDMTKFDSVDQLVDQLKADEEVTRNWS"
     gene            3770..3975
                     /locus_tag="VQ865_001986"
                     /pseudo
     CDS             3770..3975
                     /locus_tag="VQ865_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001844775.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
     gene            complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ865_001987"
     CDS             complement(4286..4579)
                     /gene="rpmA"
                     /locus_tag="VQ865_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018376869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HET3136276.1"
                     /translation="MLKMTLNNLQLFAHKKGGGSTSNGRDSQAKRLGAKAADGQTVTG
                     GSILYRQRGTHIYPGVNVGRGGDDTLFAKVEGVVRFERKGRDKKQVSVYPIAK"
     gene            complement(4596..4940)
                     /locus_tag="VQ865_001988"
     CDS             complement(4596..4940)
                     /locus_tag="VQ865_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HET3136277.1"
                     /translation="MIQAVFERAEDGELRGAEITGHAESGEYGLDVVCASVSTLAINF
                     INSIEKFAGYEPILELNEDEGGYLMVEIPKDLPSHQREMTQLFFESFFLGMANLSENY
                     SEFVQTRVITEN"
     gene            complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ865_001989"
     CDS             complement(4956..5270)
                     /gene="rplU"
                     /locus_tag="VQ865_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018374562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HET3136278.1"
                     /translation="MSTYAIIKTGGKQVKVEVGQAVYIEKLNVEAGQEVTFNEVVLVG
                     GENTVVGTPLVAGATVVGTVEKQGKQKKVVTYKYKPKKGSHRKQGHRQPYTKVVINAI
                     NA"
     misc_feature    complement(5306..5393)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            complement(5488..6087)
                     /locus_tag="VQ865_001990"
     CDS             complement(5488..6087)
                     /locus_tag="VQ865_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001858962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HET3136279.1"
                     /translation="MTFCAGYVDAYTFIVRGNTLVAGQAGNVVFLSVELIQNNVSDVR
                     DKLLTLITFIMGVFLLTIYKEKLRIVKKPILSLIPLAILSIIIGFVPQTVDNIYLVQP
                     LAFCMGLVTTAFGEVSGIAYNNAFMTGNIKRTMLAFGDYFRTKHTPFLREGFIFVSLF
                     SSFVLGVVFSAYLTIFYHEKTILGVPIMMSIFYLSMLFA"
     gene            6557..6856
                     /locus_tag="VQ865_001991"
     CDS             6557..6856
                     /locus_tag="VQ865_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008808250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HET3136280.1"
                     /translation="MMNMQNMMRQAQKLQKQMEQSQAELAAMQFVGKSAQDLVQATLT
                     GDKKVVSIDFNPAVVDPEDLETLSDMTVQAINSALEQIDETTKKKLGAFAGKLPF"
     gene            7075..>7292
                     /locus_tag="VQ865_001992"
     CDS             7075..>7292
                     /locus_tag="VQ865_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001842126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3136281.1"
                     /translation="MGQLHFITKLLDIKDPNIQILDIINKDTHKEIIAKLDYDAPSCP
                     ECGSQMKKYDFQKPSKIPYLETTGMPTR"
BASE COUNT         2335 a         1474 c         1193 g         2290 t
ORIGIN      
        1 aatattttcg gaacattcaa ctttttaact ctatttatta ctagatttca taattaaaaa
       61 gcctactgac caagctagaa agcttgatac aataggcttt ttaaagactg attatttaac
      121 agcgtcttta agagctttac cagctttgaa tgctggtact ttagaagctg caattgtcat
      181 ttctttacca gtttgtgggt tgcgaccttt acgttctgcg cgctcacgaa cttcaaagtt
      241 accaaaaccg atcaactgaa ctttttcacc agctgcaaga tagtcagcta ctgctgcaaa
      301 tacagcttca actgctgctg ctgagtcttt cttagtcaat tctgtagctt ctgctacttt
      361 agcgatcaaa tcttgtttgt ttgccatgtt aatgattcct ccaaataatt tctaattaac
      421 aaatataatc atatcctaaa atccctttta ggtcaagtta aaaacgctat ttcttcccat
      481 tttatttatt tttttaggag tggtaacgta tcaaaatagc ccaagcgttc tcacccgtgt
      541 gagtttgaat aatggaaccc gtttccaaaa cagaaattgg cttttcaaca taagcttgta
      601 agctttcttt catctctttt gcccaatcat cactaccaga atatgaaatt ccaatctctg
      661 ctacagcacg ttcagaaagc gatgttatca actcatctaa ccatttttta aatgttttag
      721 ttccacgacc tttaaccatt ggctgcaatt catggtcttt catttgcatg acaacacgga
      781 tattgagaag agagctcaac aagccagtta cacggctaat tcgtccacct ttgacaagat
      841 tttccaaagt tgaaacacca atataaagct ctgtatggtt tttaacctct tctacatgac
      901 ataaaattgc ctccatatct ttaccttctt gagctaactt cgcagcctca acaacttgga
      961 atttcagggc ttggtcagtg aaggaactat caacaacagt cacatctgca gtagataggc
     1021 tagcaccttg gcgtgctgct tctaccgtac ccgaaagagc atgggacata tgaatagcaa
     1081 gaatctggcc accatctttg cataggtctt caaaaatctc agcaaagaca cctacaggtg
     1141 gctgacttgt tttcggaaga ttcttacttt cttgcatcaa ctgaagaaat ttaccttctt
     1201 ctttcaaatc cgcatcagaa taaacaacat tatcaatcat tacagataat ggaacaattg
     1261 taatatctaa ttgctttact agttcaggtt caatagtaac agatgaatcg gttacaatct
     1321 taatttttgt catagtatca atctttctat tttaggattc agattggttt ccttacttct
     1381 aattatatca aaaaaaagat taaaaatcct aatggagtca atcaaatttt ccgtaaaatt
     1441 tgatataatc aacttataag aaaagaggtg tcctatgatt aaaaaaattt accccatttt
     1501 taccatttta ctaggtgctg ctatttatgc ttttggactg acttattttg tagttcccca
     1561 tcatctcttt gaaggagggg cgacaggtat taccctcatc acattttatc tttttaaaat
     1621 ccctgtttcc ctcatgaacc tgctgattaa tattcccctt ttcatcctag cttggaaaat
     1681 ctttggagcc aaatccctct attctagttt actaggaacc ttagctttgt ccggctggtt
     1741 agcttttttt gagcatattc cccttcatat tgatcttcaa ggtgatttac taatcacagc
     1801 ccttatagcg ggaatcctat tgggaattgg ccttggaatt atttttaatg ctggaggtac
     1861 aactggtgga actgatattc tagctcgtat tctcaacaaa tacactcata tatccatagg
     1921 aaaactgctc tttatcttag atttttgtat tctcatgttg attctcctaa tcttcaagga
     1981 tttgagattg gtttcctaca cgcttttgtt tgattttatt gtttctcgtg ttattgattt
     2041 gattggtgaa ggaggatatg ccggcaaagg ctttatgatt atcacaaaac gtcctgacca
     2101 acttgctaag gcgattaatg atgacctcgg aagaggtgtt acttttattt ctggtcaagg
     2161 ctactatagt aaagaaaatt tgaaaatcat ctactgtatt gtcggaagaa atgaaattgt
     2221 gaaaacgaag gaaatgattc atcgaatcga tcctcaagcc tttataacta ttacagaagc
     2281 ccatgaaatc ctaggagaag gcttcacctt tgaaaaagaa taaaaagagg taatgtcgtg
     2341 acctcaaaag ttagactaaa tcatctatct tttgggttac agacaacctc ttttttgttt
     2401 tatttactca agctcttaag accaattccg agttacttct tcatcagcct ttaactgatc
     2461 cactaattgg tcaactgagt caaatttggt catatcacga atgcgatcaa gccaataaac
     2521 catgacggtt tccccataaa tatcttgatt aaaatcaaaa atattgactt caaaacgtgc
     2581 ttcttctcca tcaaaggtca catttttccc gacactagcc atagcacgat acttctgtct
     2641 ttgaatctca acatcaacga cataaacgcc atctgctggc atataagtac ggtctaaaag
     2701 cactaaattc gctgtcggat aaccaattat acgaccacga gcattaccat gaaccaccat
     2761 acctcttgat ggaagcggtg cccccaaaag ttttcctgct tctttcacat ttccatctaa
     2821 aatagcttga cggatacgag ttgaactaat ctttcctttc tcatcttcta caggtggaac
     2881 aatgataact tctccatcaa agtaatcctt taaatcttct gctgtttttt tgtcagaacc
     2941 aaatgtataa tcaaaacctg caacaataat tttggcattc atagccttga tataagttgc
     3001 aaagaattct tgtgcagtga gactagcgaa ttgactacta aaatcaagga gatataattc
     3061 ttctacacct tcgcgcttta attttctttc acgttcagca gggttcaaaa tatgcaaaaa
     3121 caaatccgga tgataaggct ctaaagcgat ctttggagat tcattaaagg tcataacgac
     3181 gataggtaat aaatcctttc tcgcagcctt gttggcaaca cgaaataatt cttgatgccc
     3241 cttatgtatg ccatcaaaat agccgagaac aacgactgaa tcagatggtg tgccaatatc
     3301 tttttggttt tttataggaa tagtaataat cataaaataa ttatatcata gcgatagcta
     3361 tttctggaac agaaaatctg aaatgttgtt tttttcacat gaagtgtacc tgttttcaaa
     3421 aagcacttta ttctatcgtt gcttaactat gaactttgca atattcttct caaaaacttg
     3481 taggacatct tcaaaatttt gcaaggagtg attagacttg ttcggtaacc ataaagtgtc
     3541 atactatgtt atgtatgaaa aagcaatgca actaactcct gagaacttta aattactaat
     3601 tggtgccgaa aaggtagaat ttagaatcga ggtacaccta tggctgtaaa atttacaaaa
     3661 tgagacaact tgggcaagat gtttgaagaa tttcctaaac tccctgattt gaagcaagtc
     3721 actttccctg atgacaaaga aaaaagccaa aacagcaaag aaaaactaga tgactgcttt
     3781 ccaacaactc ccatctagtg tgcttcagac tgggctattt ttctctccat ctgttagctt
     3841 ggattctcag accgtttcag ctaaagaata tcttttccct tatcagaagg aacggctcaa
     3901 accattcaga caagtgaagg gacgacaagc caatatttga aaccagatag cagttcttat
     3961 agtcaattga aataaaatct gaagaaatcg agtaggaaac tcatatcaat ttttaacagt
     4021 gttctattcc agattcatac tcaatgaaaa ttaaagtgca aactaggaag ttagccgcag
     4081 gctgtacttg agtacggcaa ggtgaaactg acgtggtttg aatttgattt tcgaagagta
     4141 tcaatccact atacatatta aaaagtatgg atatcaaaac aaaaaaacag gctctccgaa
     4201 aactcggaaa gccttatttt aagctgtttc tagcttcctc acctttacat ttcaaggttc
     4261 gggataaaag gttcaatgga cctttttatt tagcgattgg gtaaacagaa acttgttttt
     4321 tatcgcgtcc tttacgttca aagcgtacta cgccttcaac tttagcgaac aaagtatcgt
     4381 ctccaccacg accaacgttt acacctggat agatgtgtgt accacgttga cggtaaagga
     4441 ttgatccacc tgttacagtt tgtccgtcag ctgctttagc tccaagacgt tttgcttgtg
     4501 aatcacgtcc gtttgatgta gaacctccac cttttttgtg ggcgaaaagt tgcaagttgt
     4561 taagagtcat ttttaacata atgttttcct ccgtgttagt tttctgtgat aactctggtt
     4621 tggacgaact cagaatagtt ctccgataag tttgccatac ctaagaaaaa tgattcaaag
     4681 aataactggg tcatttctct ctggtgtgaa ggaagatctt ttggtatttc aaccatcaga
     4741 tagccacctt catcttcgtt taattctagg attggttcat agcctgcaaa tttctcaata
     4801 gaattgataa agttaatggc aagcgtagaa accgatgcac acacgacatc taagccgtat
     4861 tcgccactct cggcgtgtcc agtaatttcc gcacccctca gctcgccatc ttcggctctc
     4921 tcaaagactg cttgtatcat gtgttctcct taaaattaag cgttaattgc gttgatgaca
     4981 acttttgtat atggttgacg gtgaccttgt ttacggtggc tacctttttt aggtttgtac
     5041 ttgtaagtaa caactttctt ttgttttcct tgtttttcaa cagttccaac tacagtagct
     5101 ccagcaacaa gtggagttcc gacaacagtg ttttcaccac caacaagaac aacttcgtta
     5161 aaagtaactt cttgaccagc ttcaacgttc aatttttcaa tgtaaactgc ttgaccaact
     5221 tcaactttaa cttgttttcc gccagttttg ataattgcgt atgtgctcat tatgcacctc
     5281 ctatgatttt tatgggtttc cccgattttt tgtgaagact cgcctagcat cgtgggacaa
     5341 accacttaaa cttgaataat caagcaacga tgttcgtgcg gttgcacagg atcgtgcata
     5401 gtcaactctt caagtatagc atatctccta ttttcttaca agtaataaca cctaaaatca
     5461 agctttttct tttacttttt tctgccacta ggcaaaaagc atactgagat aaaaaatgct
     5521 catcataata ggaacaccaa gaatggtctt ttcatgatag aaaatcgtca aataggctga
     5581 aaagacaacg ccaaggacaa aactactaaa caggctaaca aatatgaacc cttcacgcaa
     5641 aaaaggagtg tgcttagttc ggaaataatc tccaaaagct agcattgttc gtttgatatt
     5701 ccctgtcata aaggcattat tgtaggcaat acccgaaacc tcaccaaaag cagttgtcac
     5761 cagtcccata cagaaggcca agggctgcac tagatagata ttatctacag tttgtggcac
     5821 aaaaccaata attattgata ggattgctaa aggaatcaag gacagaatag gttttttcac
     5881 aattctcaat ttttccttat aaatcgttaa taaaaagact cccattataa acgttattaa
     5941 ggttaaaagc ttatccctaa catccgaaac attattttgt attagctcta ccgaaagaaa
     6001 gacaacattt ccagcttgtc cagctacaag ggtattccct cgaacaataa aagtgtaagc
     6061 atccacatat ccagcacaaa atgtcaaaaa agtgctaacc ttttagactg acgtgatatt
     6121 tttcttatag gtaataacct cattttccct cccattgtat tttctcttag aaatattgta
     6181 ccatttcttt ctaaaaaatc gtagactacc atttagattt tactattagc ataaaaataa
     6241 taatagacaa ctatttatcc aaaaatagat agaggtaaca tgtttgcaaa caaagcatac
     6301 gaacctttag taaaatcatt tccatgaaac tagaatagag cccctcttag caaaaatcat
     6361 tattttaatt tatttctaat cactccttga cataaataac tctcaccaat aaaagactat
     6421 gtcttaaaaa aatggtataa taaaatcaat acctgggctt gatggctatg ctactaataa
     6481 caattaggag agaaaatcag gcacttgtta acaacaagga ttatcccctt gagatgaaag
     6541 gaactttaga aatcttatga tgaacatgca aaacatgatg cgtcaagcac aaaaacttca
     6601 aaaacaaatg gaacaaagcc aagctgaact tgctgctatg caatttgttg gcaaatctgc
     6661 tcaagatctt gtccaagcga ccttaactgg cgataagaaa gttgtcagca ttgatttcaa
     6721 tccagctgtc gttgacccag aggaccttga gactctttct gatatgaccg ttcaagccat
     6781 caactctgct cttgaacaaa tcgatgaaac tactaagaaa aaactgggtg ctttcgctgg
     6841 gaaattgcca ttctaaaaac aaggagctag aacaatactt gtcgataaca aaggctaaga
     6901 aaggtgcaaa aattataaaa aacgcatagt atcaagcaac ctaaaacttt gggctctata
     6961 atatttgtag tgggtaaatc cactatagat attatggagc ctattttatt gtagaaaaaa
     7021 atcccataag atctataatg aaaagcgacc aaacaactca ttagaaagat tcatatggga
     7081 caattacatt ttatcacaaa attactagac attaaagacc ctaatatcca gattttagac
     7141 atcatcaata aggatacaca caaggaaatc atcgccaaac tggactacga cgccccatct
     7201 tgccctgagt gcggaagtca aatgaagaaa tatgactttc aaaaaccgtc taagattcct
     7261 taccttgaga caactggtat gcctactaga at
//
LOCUS       DAVBOG010000076         6938 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.077, whole genome shotgun sequence.
ACCESSION   DAVBOG010000076 DAVBOG010000000
VERSION     DAVBOG010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6938
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.077"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(57..287)
                     /locus_tag="VQ865_001993"
     CDS             complement(57..287)
                     /locus_tag="VQ865_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000832182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136282.1"
                     /translation="MKRVILVAVIQAVVLFFIIGALAYAFKGDFFYNYLAVVFAPIAG
                     VLRFGTAYITEIVLPRKAAEIAEKRKAGKNSK"
     gene            complement(305..946)
                     /locus_tag="VQ865_001994"
     CDS             complement(305..946)
                     /locus_tag="VQ865_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3136283.1"
                     /translation="MKLLKNLGWILLALLSFLFIYGFIQGLATASLALGASPYAVTLL
                     YVALAGVYVYGIYKWYQKAPVHIEKSGFNRFIWLPVLVWFLSLVVQFFLPDDPSVNQQ
                     IATDLTLSQPLFSFFAVVIFAPLTEEIVFRGMLARYLFPKQDNSKRTLIFLLVSSLLF
                     ALIHFPGDVQQFFVYFSLGFSLGLAYISRKGLVYSISLHALNNLVGFLMILML"
     gene            complement(958..1692)
                     /locus_tag="VQ865_001995"
     CDS             complement(958..1692)
                     /locus_tag="VQ865_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001864354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3169 family protein"
                     /protein_id="HET3136284.1"
                     /translation="MKKKRRLLFLMSIVLGGFLGMFVGMFKARVESHEIILDVKALMP
                     WISAICLLIGFISMFLTFNFLKKSRKFHSLYQEEMDDDLNETYYVQMYRNLEFGTIAF
                     NITGVAIPLAIFISLSEVIILHTNPQTFFLSFLLFVVFLVAQKSLFKTIAIVRQFDLE
                     FFATPKDVLNYINSYDEGERQANLEQSFRILFQLHQYVLPALYIFLIIISFLTGEIQL
                     LAFLLVGAIHVYINVMQLPMVKRYFK"
     gene            complement(1695..1892)
                     /locus_tag="VQ865_001996"
     CDS             complement(1695..1892)
                     /locus_tag="VQ865_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001046145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136285.1"
                     /translation="MNKYKVIYYVVVIALLVSVFLLIGMDLSWFNPYQSDQFVWVYFA
                     LIPVTEWIEKKSKNLASEKGE"
     gene            complement(1892..2098)
                     /locus_tag="VQ865_001997"
     CDS             complement(1892..2098)
                     /locus_tag="VQ865_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HET3136286.1"
                     /translation="MQLKNRLKELRARDGLNQTDLAKLAGVSRQTISLLERDEYTPSI
                     IIALKISQIFNETVESVFRLEEDE"
     gene            complement(2108..2422)
                     /locus_tag="VQ865_001998"
     CDS             complement(2108..2422)
                     /locus_tag="VQ865_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001829577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136287.1"
                     /translation="MWVLGFILFMIFFYSNNSKKIKKLENKIKKLERKEKGNAEMSRL
                     LQEMIGKEPIITGVYIGPDNWEVVDVDEEWVKLRSVDNTGKEKFKLQRIEDIQTVEFD
                     GE"
     gene            complement(2647..2727)
                     /locus_tag="VQ865_001999"
                     /pseudo
     CDS             complement(2647..2727)
                     /locus_tag="VQ865_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001820552.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-galactopuranose mutase"
     gene            complement(2718..4007)
                     /locus_tag="VQ865_002000"
     CDS             complement(2718..4007)
                     /locus_tag="VQ865_002000"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HET3136288.1"
                     /translation="MKLQKPKGTQDILPAESAKWQYVEGFAREIFKRYNYAEVRTPIF
                     EHYEVISRSVGDTTDIVTKEMYDFYDKGDRHITLRPEGTAPVVRAYVENKLFAPEVQK
                     PSKFYYMGPMFRYERPQAGRLRQFHQIGVECFGSSNPATDVETIVMAAHFLKEIGIQG
                     VKLHLNTLGNPESRAAYRQALIDYLTPLKETLSKDSQRRLEENPLRVLDSKEKEDKVA
                     VENAPSILDFLDEESQTHFDAVSQMLENLGVDYIIDTNMVRGLDYYNHTIFEFITEIE
                     GNDLTVCAGGRYDGLVAYFGGPETAGFGFGLGVERLLLILEKQGVALPIENALDVYIA
                     VLGDGANVKALELVQALRQQGFKAERDYLNRKLKAQFKSADVFAAKTLITLGESEVES
                     RQVTVKNNQTREEVQVSLETISQNFSEIFEKLGFYTQ"
     gene            complement(4104..5333)
                     /locus_tag="VQ865_002001"
     CDS             complement(4104..5333)
                     /locus_tag="VQ865_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012677131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HET3136289.1"
                     /translation="MKLLFRNPAYRILTLSRFFNAFGASIFNLVFIVYASTLSQASFA
                     VAMANIVMILPTLFTVFAGIRADYTRDKVKWMVYSGLFQAVLFFLAALVVQQASLFAF
                     SILCLINVISDIISDFAGGLRMPLIKEKVAEDDLMEAYSFSQFITYISAIGGQAFGVW
                     LLALSVNNFSLVAGINACFFLVSATILFLGKSKLSLSMSSADGENLKNEKLSIKDQFL
                     TIYRNLRLVFLKSGQKNFGFMLFAVLLINSLGGALGGIYNIFFLSHSLLNFSYTEALF
                     INQFCVLVAVIISSLTGNDYFGKQSLPRLMMWATVGLSLVGLANLFNQVVLGLLFLFF
                     TLYVSGKVQPKISAMLMKNLAPEVLARTSNFLGLLFTLSIPVGTACFSLVAVWNIQLT
                     WMLFVGLSLLAIFFDNS"
     gene            complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ865_002002"
     CDS             complement(5526..6377)
                     /gene="rgg"
                     /locus_tag="VQ865_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000434947.1"
                     /note="Rgg, as the term is used in Streptococcus
                     pneumoniae, is the lone quorum-sensing system
                     transcriptional regulator related to proteins Rgg1, Rgg2,
                     Rgg3, and Rgg4 of Streptococcus pyogenes; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quorum-sensing system transcriptional regulator
                     Rgg"
                     /protein_id="HET3136290.1"
                     /translation="MEQIGKVFRQLRESRNISLRQATGGQFSPSMLSRFETGQSELSV
                     EKFLFALENISASVEEILFLARGFQYDTDSELRKEITDVLEPKNIAPLEDLYRREYQK
                     HAHSHNKQKHILNAIIIKSYMKSIDERVDLTAEEGKVLHDYLFSTEIWGIYELNLFSV
                     SSPFLSVSLFTRYVREMVRKSDFLMEMSGNRNLFHTILLNGFLASIECEEFTNAYYFK
                     RVIEEHFYKENETYFRIVYLWAEGLLDSKQGRVKEGQKKMEDAVRIFEMLGCNKSAEY
                     YRNTTEC"
     gene            6501..6842
                     /locus_tag="VQ865_002003"
     CDS             6501..6842
                     /locus_tag="VQ865_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003080443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HET3136291.1"
                     /translation="MRDDIKINDRALALQDQIIEKLEKVFDTDVELDVYNLGLIYEIN
                     LDETGLCKIVMTFTDTACDCAESLPIEIVAGLKQIEGIKDIKVEVTWSPAWKITRISR
                     YGRIALGLPPR"
BASE COUNT         2248 a         1441 c         1275 g         1974 t
ORIGIN      
        1 ctctttgatt ttcattgagt ataatacaaa aatccgatga acttcaccgg actcttttat
       61 tttgaatttt tgcctgcttt acgcttttca gcgatttcgg ctgcctttcg aggcaagaca
      121 atttccgtta tgtaagccgt cccaaaacgc agtacacctg caataggagc aaagacaact
      181 gctagatagt tatagaagaa atcgcctttg aaggcataag ctagcgctcc aatgatgaaa
      241 aatagaacga ctgcctgaat cactgctact aaaattactc gtttcatgtg acctcctgac
      301 tctattatag catgagaatc atcaaaaagc cgactaaatt attcaaagcg tgaagagaaa
      361 tactgtagac cagacctttt ctgctaatgt aagccaaacc caaactaaaa ccaaggctaa
      421 aatagacaaa aaattgttgc acatcacctg gaaaatgaat caaggcaaat agaagactag
      481 ataccagaag aaaaatcagg gttcgtttac tattgtcctg cttaggaaag agatagcgtg
      541 ctaacatccc tctaaaaaca atctcttccg tcaaaggagc aaaaataacc acagcaaaga
      601 atgagaaaag tggttgagac aaggtcaagt ctgtcgctat ttgttgattt actgaaggat
      661 catctggcaa gaagaattga acgaccagag ataagaacca aaccaagaca ggaagccaaa
      721 taaatcgatt aaagccgctc ttctcaatat gaacaggagc cttctgatac catttgtaaa
      781 tgccgtacac atatactcca gccaaggcca catagagtag agtaacagca tagggtgaag
      841 cgcctaaagc aagcgacgca gtcgcgagcc cctgaataaa gccatagata aataaaaagg
      901 atagaagggc tagaagaatc cagccaaggt ttttaagtaa tttcatagat aactccttta
      961 tttgaaataa cgttttacca taggtaactg catcacattg atataaacat ggatggctcc
     1021 tacaagcaag aaagctagta actgaatctc tcctgtcaag aaagaaatga taataagaaa
     1081 aatatataag gctggtaaga catattggtg taattggaat aaaattcgaa aactctgttc
     1141 caaattagcc tgacgctccc cttcatcata agaatttata tagttcaaga catcctttgg
     1201 tgtagcgaaa aattccaaat caaactgacg aacaatcgca atggttttaa aaagagattt
     1261 ttgagcgact aagaatacca caaagagtaa gaaagaaagg aaaaatgttt gagggtttgt
     1321 atgcaatata atcacctcac ttaatgaaat aaaaatagcc aatggaatcg ctacacctgt
     1381 aatattaaaa gcaatggttc caaactcaag attccgatac atttgcacat aataggtttc
     1441 attcagatcg tcatccattt cctcttgata caaggaatga aattttctgc ttttctttaa
     1501 gaaattgaaa gtcaaaaaca tactaatgaa acctatcagt aaacaaatag ctgatatcca
     1561 tggcatcaag gcttttacat ctaaaataat ttcgtgggat tcgacacgtg ccttaaacat
     1621 ccctacaaac atgcccaaga acccccccaa gacaatagac atcaaaaata acaatctacg
     1681 tttctttttc atattcattc tcctttttca cttgctagat ttttggattt cttttcaatc
     1741 cattcagtta ctgggatgag agcaaagtag acccaaacaa attggtcgct ttgataggga
     1801 ttaaaccagc ttaggtccat cccaatcagt agaaatacgc tgactaataa agctatgacc
     1861 actacataat aaatcacttt atacttgttc atcactcgtc ctcctccaaa cgaaataccg
     1921 attcgactgt ttcgttgaaa atttgagata ttttcagggc aatgataatg gatggggtgt
     1981 actcatcccg ttctagtagg ctaatggtct gtctggaaac ccctgccagt ttggctaggt
     2041 cggtttgatt gagaccatcg cgagctcgaa gctcttttag acgatttttt agttgcacgt
     2101 tacacaccta ctctccgtca aattcaacgg tttggatatc ttcaatacgt tgcaacttga
     2161 atttttcttt tcccgtatta tcaacactac gtagtttgac ccattcctca tcaacatcca
     2221 caacttccca gttatctggc ccaatataca ctcccgttat aattggttcc tttccaatca
     2281 tttcttgtaa taatctcgac atttctgcgt ttcctttctc ttttcgctca agttttttga
     2341 ttttattctc tagtttcttg atttttttag aattattaga ataaaagaaa atcataaata
     2401 gtataaatcc tagtacccac attataactc ctttctgctt cctatttctt aacttgaatt
     2461 cattgtaaca tatctttttc tttttgacaa ttatagttgt caaaaagttt atgatttttg
     2521 tcattttgca aaagaaaaag gtcaggagta agttcctgac cactttatct atcattaata
     2581 ctcttctaaa atctcttcaa accacgtcag cttcaccttg ccgtaggcat ggttactgac
     2641 ttcgtcagtt tcatctacaa cctcaaaacc atgttttgag caacctgcgg ctagcttcct
     2701 agtttgctct ttgattttca ttgagtataa aatcctagtt tttcaaagat ttctgagaag
     2761 ttttggctga ttgtctcaag tgacacttgc acttcttctc gggtttggtt gttcttgact
     2821 gtcacttgtc tgctttcgac ttcgctctct cctagggtga tgagggtctt agccgcaaag
     2881 acatcggctg acttgaactg agctttgagc ttacggttga ggtaatcacg ctctgctttg
     2941 aaaccttgtt ggcgaagagc ttggactagt tctagggctt tgacatttgc tccatcaccc
     3001 aagactgcga tatagacatc tagggcattt tcgataggga gggccacgcc ttgtttttca
     3061 aggatgagaa gcaggcgctc tacaccaagc ccaaaaccaa atccagcagt ttcagggcct
     3121 ccaaagtaag caaccaaacc atcgtagcga ccacccgcac agactgtcaa gtcattgccc
     3181 tcaatctctg tgataaactc gaaaatggtg tggttgtagt agtccagacc acgcaccata
     3241 ttggtatcga tgatgtaatc tactccaaga ttttccaaca tctgactcac agcatcaaaa
     3301 tgagtttggc tttcttcatc aagaaagtcc aagatagacg gcgcattctc tactgccacc
     3361 ttgtcttctt tttccttaga gtccaagaca cgaagaggat tttcctccaa gcgacgttgg
     3421 ctatccttag acaaggtctc cttgagcggt gtcaaatagt caatcaaggc ttggcggtag
     3481 gctgcacggc tctcaggatt tccaagagtg ttgaggtgca atttgacacc ttgaataccg
     3541 atttccttca aaaaatgggc tgccataacg attgtttcca catcggtagc tggattgcta
     3601 gaaccaaaac actcaacacc aatctggtgg aattggcgca agcgccctgc ctgtggacgc
     3661 tcataacgga acataggtcc catgtagtag aacttgcttg gcttttgcac ttctggagcg
     3721 aagagtttat tttccacata ggcacggaca acgggcgcag ttccttctgg acggagggta
     3781 atatggcggt cacccttgtc atagaaatcg tacatttcct tggttacaat atctgttgta
     3841 tctccgacag agcggctgat aacctcgtaa tgctcgaaaa taggcgtacg cacttctgcg
     3901 tagttgtagc gcttgaaaat ttcacgggca aagccctcaa cgtactgcca cttagcagac
     3961 tcagcaggta aaatatcctg cgttcctttt ggtttttgta atttcatagg gaatcctctt
     4021 taaacttaat agtcttattt taccataaat agagggatta aaacagtaag aaaaaaatta
     4081 ggatttagat atcatttttg agattaagaa ttgtcaaaaa aaatagctag caaggaaaga
     4141 ccaacaaata gcatccaagt caactgtata ttccatacgg ctactagtga aaaacaagct
     4201 gttcccacag gtatggataa ggtaaacaat agacctaaaa aattactagt acgagctaga
     4261 acctctggag ctagattttt catgagcatg gcactaatct ttggttgaac tttaccagac
     4321 acatacagag taaagaagag aaatagcaaa ccaagcacga cttgattgaa taaattagcc
     4381 aaaccaacta gactaagccc tacggtcgcc cacatcatca atctaggcaa ggactgcttc
     4441 ccaaaataat cattgcccgt aaggctactg atgatgactg ctactaaaac acagaattga
     4501 ttgataaata gtgcctctgt ataagaaaaa ttcaagagag aatggctcaa aaagaagata
     4561 ttataaattc cacccaaagc gccacccaag gaattaataa gcaagacagc aaagagcata
     4621 aaaccaaagt ttttctgtcc acttttaaga aaaacgagac gtaaatttcg gtaaattgtt
     4681 aggaactggt ctttgataga aagcttctca ttttttaagt tttcaccatc agcagatgac
     4741 attgacaggc tcaatttgct ttttcctaaa aagaggatag tggctgatac taggaaaaag
     4801 caggcattga ttcccgcaac gagagaaaaa ttgttgaccg atagagctaa gagccagact
     4861 ccgaaagctt gaccaccaat agctgaaata taggtgatga actgtgaaaa agaataagcc
     4921 tccatcagat catcttcagc tactttttcc ttaataagag gcatacgcag gccacctgca
     4981 aaatcactga tgatatcact aatgacattg atcaaacaca ggatagaaaa ggcaaagaga
     5041 ctagcttgct gaacaactag ggctgctaga aaaaatagaa ccgcctgaaa caaaccgcta
     5101 tagaccatcc atttgacctt gtccctcgtg taatctgccc gaatccctgc aaaaactgta
     5161 aagagggtcg gaagaatcat gacaatattc gccatagcaa cagcaaaaga tgcttgtgac
     5221 aaggtcgatg catagacgat aaagaccagg ttgaaaatcg aagcaccaaa agcattgaag
     5281 aagcgtgata aagtcaaaat tctataagct ggatttctaa acaatagttt catagataat
     5341 ctcccttctt gttcgaacct ctatatgaag tatgactata gtatagcact tagaaatttg
     5401 agagggagaa ctcttgaata tatgcaacaa ataaaatgag caaaaagaaa cgatagaact
     5461 tttgtaatga cctgagagag ggcaatagtt ctatcgcttc aaattttttc ttggtttgca
     5521 gatattcaac attcggtcgt atttctatag tattcggcag atttattaca gccaagcatc
     5581 tcaaaaatac ggacagcatc ctccatcttt ttctggcctt ccttgactct accttgcttg
     5641 ctatcaagga gaccttctgc ccacagataa acaattcgga aataggtctc attttccttg
     5701 tagaaatgct cttcgataac acgtttaaaa taataggcat tggtaaattc ttcacactca
     5761 atactagcta aaaagccgtt caatagtata gtatgaaaaa ggtttcgatt gccagacatt
     5821 tccattagaa aatcagattt acgtaccatt tctcgtacat atctagtaaa aagagaaaca
     5881 gataaaaatg gagaactgac tgaaaataaa ttgagttcat agattcccca gatctcggta
     5941 gaaaacaaat aatcatgaag gacttttcct tcctctgctg ttaagtctac cctttcatct
     6001 atgctcttca tataagactt gataataatg gcatttagaa tatgtttctg tttgttgtga
     6061 gaatgggcat gcttttgata ctccctgcga tataagtcct caagaggtgc tatattcttt
     6121 ggttccaaga catctgtaat ttcttttctc aactcagaat ctgtatcata ctggaaacct
     6181 ctcgccagaa agaggatctc ctccacactg gcagatatat tttccagagc aaatagaaac
     6241 ttttccaccg aaagctcact ctgacctgtt tcaaaacggg acaacataga cggcgaaaat
     6301 tgtcctccgg ttgcttgtct cagtgagata tttcttgact ctcgtaattg tctaaagact
     6361 tttccaatct gctccataga cttccccttg attccgtatt ttcttcattt tatcatattt
     6421 ttcagaaaat taatcaaaag cttgccaaat tgtcagaatt atgagaaaat agaggatatt
     6481 tatcacatgg agggactgct atgagagacg atatcaaaat caatgaccgt gctttggcct
     6541 tgcaagacca aattatcgaa aaactagaga aagtttttga tacagatgtg gaattggatg
     6601 tttacaatct aggtctgatt tatgaaatca atctggatga aacggggctc tgcaagattg
     6661 tcatgacctt caccgatact gcctgtgatt gcgccgaaag cctgcctatt gaaattgtgg
     6721 caggtctgaa acaaatcgag ggtatcaaag atatcaaggt tgaagttacc tggtcgcctg
     6781 cttggaaaat cacacgaatc agtcgctatg gccgtattgc ccttggacta ccacctcgtt
     6841 aagcaggcca atcactttta aagatgaaaa aagcaagccg aaaatggctt gctttttgat
     6901 actcaatgaa aatcaaaggg caaactagaa aactagcc
//
LOCUS       DAVBOG010000077         6837 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.078, whole genome shotgun sequence.
ACCESSION   DAVBOG010000077 DAVBOG010000000
VERSION     DAVBOG010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6837)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6837)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6837
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.078"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(58..384)
                     /locus_tag="VQ865_002004"
     CDS             complement(58..384)
                     /locus_tag="VQ865_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001822577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3136292.1"
                     /translation="MVEYISRKYFLTEEEFQAEKICNQSLVELFQKKYSWHSLNDFGS
                     STYDKNYASIFYEYWRSFLTVDKLVENLGSVQAVLDSYHLWANTEKTFPLLDWFVQQK
                     LIEKEI"
     gene            complement(351..635)
                     /locus_tag="VQ865_002005"
     CDS             complement(351..635)
                     /locus_tag="VQ865_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HET3136293.1"
                     /translation="MDNLYLVKDDSQLATFRDFVVRNTEKLKDYQSFLKNELAVCDLP
                     QAVIWSDFNAATQIIRESAVPAYTNNRRMVMTLISGSKRGWLNILVASIS"
     gene            complement(908..1750)
                     /locus_tag="VQ865_002006"
     CDS             complement(908..1750)
                     /locus_tag="VQ865_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HET3136294.1"
                     /translation="MNTYQLNNGVEIPVLGFGTFKAKDGEEAYRAVLEALKAGYRHID
                     TAAIYQNEESVGQAIKDSGVPREEMFVTTKLWNSQQTYEQTRQALEKSIEKLGLDYLD
                     LYLIHWPNPKPLRENDAWKTRNAEVWRAMEDLYQEGKIRAIGVSNFLPHHLDALLETA
                     TIVPAVNQVRLAPGVYQEQVVAYCREKGILLEAWGPFGQGELFDSKQVQEIAANHGKS
                     IAQIALVWSLAEGFLPLPKSVTTSRIQANLDCFGIELSHEERETLKTIAVQSGAPRVD
                     DVDF"
     gene            complement(1864..3255)
                     /locus_tag="VQ865_002007"
     CDS             complement(1864..3255)
                     /locus_tag="VQ865_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013193417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HET3136295.1"
                     /translation="MNKSRLGRGRHGKTRHVLLALIGILAISICLLGGFIAFKIYQQK
                     SFEQKIESLKKEKDDQLSEGNQKEHFRQGQAEVIAYYPLQGEKVISSVRELINQDVKD
                     KLESKDNLVFYYTEQEESGLKGVVNRNVTKQIYDLVAFKIEETEKTSLGKVHLTEDGQ
                     PFTLDQLFSDASKAKEQLIKELTSFIEDKKIDQDQSEQIVKNFSDQDLSAWNFDYKDS
                     QIILYPSPVVENLEEIALPVSAFFDVIQSSYLLEKDAALYQSYFDKKHQKVVALTFDD
                     GPNPATTPQVLETLAKYDIKATFFVLGKNVSGNEDLVKRIKSEGHVVGNHSWSHPILS
                     QLSLDEAKKQITDTEDVLTKVLGSSSKLMRPPYGAITDDIRNSLDLSFIMWDVDSLDW
                     KSKNEASILTEIQHQVANGSIVLMHDIHSPTVNALPRVIEYLKNQGYTFVTIPEMLNT
                     RLKAHELYYSRDE"
     gene            complement(3490..3867)
                     /locus_tag="VQ865_002008"
     CDS             complement(3490..3867)
                     /locus_tag="VQ865_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001833802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3136296.1"
                     /translation="MICQFIRDMLDLPAKNVTILEGSNIHVLPSMPYSAQDFYTSIDV
                     LAELDNGIQVIIEIQVHHQNFFINRLWAYLCSQVNQNLEKIRQREGDTHQSYKQIALV
                     YAIAIVDSNYFSDDLAFHSFIVK"
     gene            4082..5059
                     /locus_tag="VQ865_002009"
     CDS             4082..5059
                     /locus_tag="VQ865_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002206301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HET3136297.1"
                     /translation="MLKLGVIGTGAISHHFIEAAHTSGEYQLVAIYSRKLETAATFAS
                     RYQNIQLFDQLEVFFKSSFDLVYIASPNSLHFAQAKAALSAGKHVILEKPAVTQPQEW
                     FDLIQTAEKNNCFIFEAARNYHEKAFTTIKNFLTDKQVLGADFNYAKYSSKMPDLLAG
                     QTPNVFSDRFAGGALMDLGIYPLYAAVRLFEKANDATYHAQQLDNSIDLNGDGILFYP
                     DYQVHIKAGKNITSNLPCEIYTTDGTLTLNTIEHIRSAIFTDHQGNQVQLPIQQAPHT
                     MTEEVAAFAHMIQQPDLNLYKTWLYDAGSVHELLYTMRQTAGIRFEAEK"
     gene            5056..6138
                     /locus_tag="VQ865_002010"
     CDS             5056..6138
                     /locus_tag="VQ865_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HET3136298.1"
                     /translation="MKTKLPTEWQELSDQLGFQEFTPIQTQLFEPLLAGENLLGVSQT
                     GTGKTLAYLLPSLLRLQKKKAQQLLILAPNTELAGQIFDVCKTWAEAIGLTAQLFLSG
                     SSQKRQIERLKKGPEILIGTPGRIFELIKLKKIKMMNVETIILDEFDQLLDDSQIHFV
                     EKITHYAPRDHQLVYMSATTKFDQEKIVPNTRTIDLSDQKLDNIQHFYMQVDQRHRVD
                     MLRKLAHVEDFRGLVFFNSLSDLGNAEEKLQYRDILTVSLASDVNVKFRKIILEKFKD
                     NQLTLLLATDLLARGIDIDSLECVVNFDIPRDSETYTHRAGRTGRIGKEGYVITLVTH
                     PEEIKKLKKFASIREIVLKNQELYIK"
     gene            complement(6202..6837)
                     /locus_tag="VQ865_002011"
                     /pseudo
     CDS             complement(6202..6837)
                     /locus_tag="VQ865_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT         2053 a         1496 c         1160 g         2128 t
ORIGIN      
        1 tctgccactg atgcagtgaa atgtcaattt cttagacatt gtttactcct ttagttttta
       61 tatttctttt tcaattaatt tctgctgaac aaaccaatct aacaagggaa aagttttttc
      121 tgtatttgcc cataaatgat aagaatctaa gaccgcttgt acactaccta aattttctac
      181 caacttatct actgtcaaaa agctgcgcca gtattcataa aaaatacttg catagttctt
      241 atcataagtc gaagaaccaa aatcattcaa tgaatgccaa ctatacttct tctgaaaaag
      301 ttctacgaga gattgattac aaattttttc cgcttgaaat tcctcttctg tcaagaaata
      361 cttgcgacta atatattcaa ccatcccctc ttcgaaccag atataagagt cataaccatt
      421 cgtctattat ttgtataggc tggaacagcg ctttccctaa taatctgtgt agcagcatta
      481 aaatctgacc aaataacggc ttgcggtaaa tcacagactg caagttcatt ctttaaaaaa
      541 gattgataat ctttcaactt ttcagtattt cttactacaa aatcacgaaa tgtagctagt
      601 tgactatcgt cttttacaag ataaaggttg tccacggctc tcctttcttt cacacaatag
      661 actgaataag caaaagaacc acatctgaca atcctaggtt gatttaacct aggggcgtca
      721 gaaacgcggt tccaccctaa tttattactt cattgttttt gaaaatacta cagaaagcgc
      781 cagctcatta ttttgcccta cttggctccc actgtcccaa gctcgcttga agaacgccat
      841 aagactttct ttcctgctga ctattatatc aaaaattaga ataatgtaca attcttttta
      901 tgattttcta gaaatccaca tcatcaactc gtggagcacc cgattgaaca gcaatcgttt
      961 ttaaggtttc tctctcctca tgactcagtt caattccaaa gcaatcaaga ttagcttgaa
     1021 tacgagaggt tgtgacagat tttggaagtg gtaaaaatcc ttctgccaag ctccagacca
     1081 aggctatctg agcaatcgat tttccgtgat ttgctgcgat ttcttgcact tgcttgctat
     1141 caaatagttc tccctgacca aaaggccccc aagcttccaa taaaattccc ttttcacgac
     1201 agtaagctac gacttgttct tgatacacac ctggcgccaa gcgaacttga ttgaccgcag
     1261 gaacgatagt tgcagtttca agcaaggcat ccaaatgatg gggaagaaaa ttgctaacgc
     1321 cgatagcacg gattttccct tcttgataga ggtcttccat cgctctccaa acttccgcat
     1381 tgcgagtttt ccatgcgtca ttttctctga gcggttttgg gttcggccaa tgaatcaaat
     1441 acaaatccaa ataatccaag cccagttttt ctatagattt ttccaaagct tgacgagttt
     1501 gctcataggt ttgctgacta ttccaaagct tggtagttac gaacatttct tcacgtggaa
     1561 ctccgctatc tttgattgct tgaccaacac tttcttcatt ctgataaatc gccgccgtat
     1621 caatatgacg ataaccagcc ttcaaggctt ctaacactgc acgataggct tcttctccat
     1681 ccttagcctt aaaagttcca aatcccaata ctggaatttc tactccatta tttaattgat
     1741 aggtattcat atgcttctcc ttctatttta ttcatcaatt atagcataaa acatttttta
     1801 agtagtacta tattctgtaa aaaataagtc tgtcaaatat ctaacagacc tattttttct
     1861 tgcttattca tcacgactat agtacagctc atgagctttt aggcgagtat tgagcatctc
     1921 tggtatggtc acaaaggtat aaccttgatt tttcaaatac tcaatgaccc ttggcaaggc
     1981 attgactgtc ggactgtgaa tatcatgcat caaaacgata gagccgttag ctacttgatg
     2041 ctgaatttct gtcaaaatag atgcttcatt tttactcttc cagtccagac tatccacatc
     2101 ccacatgata aagctcaaat ccaagctatt gcgaatatca tctgtaatag caccataagg
     2161 tggacgcatg agtttagaac tagaacccag cactttagtt agcacatcct cagtatcagt
     2221 aatctgcttt ttagcttcat caagagagag ttgcgagaga atcggatggc tccaactatg
     2281 gtttccaaca acatgacctt cagattttat cctcttcacc aagtcctcat tcccagaaac
     2341 atttttccca agcacaaaga aagtcgcttt aatatcatat ttagctaggg tctctaatac
     2401 ctgcggggtc gttgctggat ttggaccatc atcaaaggtt agagcgacaa ctttttgatg
     2461 tttcttatca aagtaagatt ggtacaaggc cgcatctttt tcgagtaagt acgaagattg
     2521 gataacatca aagaaagcag atactggcaa ggctatctct tctaaatttt caaccacagg
     2581 acttggataa aggataatct gactatcctt gtaatcaaaa ttccatgcag acaagtcttg
     2641 gtcagagaag ttttttacaa tctgctcact ctggtcttga tctatttttt tatcctctat
     2701 gaaggaggtc aactctttta tcagctgttc cttagcctta ctagcatctg aaaacagttg
     2761 gtcaagtgta aaaggttgcc catcttctgt taagtgaacc tttcctagac tggtcttttc
     2821 agtctcttca atcttaaaag caactaaatc atagatttgt ttggtcacat tacgattaac
     2881 gactcccttt aaacctgact cttcttgctc tgtatagtag aaaacaagat tgtccttact
     2941 ttctagcttg tccttaacat cttgatttat cagctcccta acagaggaaa tcactttctc
     3001 cccttggaga ggataatagg caatcacttc ggcttgcccc tgacgaaaat gctccttctg
     3061 atttccctca ctcaattgat catctttctc ttttttgagc gattcaatct tttgctcaaa
     3121 acttttttgc tggtagatct taaaagcaat aaatccgcct aataggcaaa tagaaattgc
     3181 taaaatacca atcaaagcca ataatacatg tctcgttttc ccgtgtctgc cacgtcctag
     3241 tctactttta ttcatattta tatcataaca aatttgagca ataatttcaa tgatacaatt
     3301 tggcaatcca caattcctct agcaagccaa agcatcttac atcaactcca acatccgtat
     3361 ctgtagagat tatgtagttt tctatctatg gaatttctag tagattgaag ctagaatagt
     3421 agacctatac ttctaaaaca ttgttagaaa tcgatttgac tgtcctgatc gatttgtcct
     3481 gttctcattt cattttacta taaaactatg aaaagctagg tcatctgaga agtaattact
     3541 atcgacaatt gcgatagcgt atactagtgc gatttgtttg tagctctggt gggtatcacc
     3601 ttcacgttgg cgaatttttt ctaggttttg attaacctga ctgcacagat aagcccatag
     3661 gcgattgatg aaaaaattct gatgatgaac ctgaatttcg atgataactt ggattccatt
     3721 atctaactcc gccaagacgt ctatactagt atagaaatct tgcgctgagt agggcatgga
     3781 aggcaagacg tgaatgttac ttccctccaa aatcgtcaca ttttttgctg gcaagtccag
     3841 catatcgcgg ataaattgac aaatcattag ttgggctgat acctggatgt ctgagaatcc
     3901 tccttttcct ccttctatta tagcacattt ttaaatctag gtttgctaga ttctatgctt
     3961 ctatctattt attcggaaaa gaaagctaat agcttatttg aaattttctc ctctctgttg
     4021 gatagtcccg tctatctatg ttataatgaa agaaggattt aaaatcggaa aaggagtatt
     4081 tatgctaaaa ttaggtgtca tcggaactgg cgctatcagc catcatttca tagaagcagc
     4141 ccataccagt ggagaatacc aactggtcgc aatctattct agaaaactag aaactgcagc
     4201 aacctttgct tctcgctatc agaatatcca actattcgat caattagaag tcttcttcaa
     4261 atcttctttt gatttagtct atatcgccag tccaaactcc ttacattttg ctcaggcaaa
     4321 agctgccttg tctgctggta aacatgttat tctcgaaaag ccagctgtca ctcaaccaca
     4381 agaatggttt gatttgattc aaacagctga aaaaaataac tgttttatct ttgaagcagc
     4441 tcgtaattac cacgagaaag cctttactac tatcaaaaac tttttaacag ataagcaagt
     4501 gttaggagca gatttcaact atgccaaata ctcttccaag atgcctgact tgttggctgg
     4561 acaaacacca aatgtctttt cagaccgttt tgctggtgga gccctcatgg atttggggat
     4621 ttatcccctc tatgctgctg ttcgtctttt tgaaaaagct aatgacgcga cttaccatgc
     4681 tcaacagctt gacaatagca ttgacctaaa tggagatggt atcctcttct acccagacta
     4741 tcaagttcac atcaaggctg gaaaaaacat cacttccaat cttccttgcg agatttatac
     4801 aacagatgga accttgactc tcaacacgat tgagcatatt cgctcagcta tttttaccga
     4861 ccaccaagga aatcaagtcc agcttcctat ccaacaggct cctcatacga tgactgagga
     4921 agtcgctgca tttgcacaca tgatccagca accagatctg aatctctaca aaacttggct
     4981 gtatgatgca ggctctgttc atgagctact atataccatg cgccagactg ctggcattag
     5041 atttgaggca gaaaaatgaa aaccaaacta ccgactgaat ggcaagaact gagtgaccaa
     5101 ctcggtttcc aagaattcac ccccattcaa actcaactat ttgagcccct tcttgctgga
     5161 gaaaacctcc taggagtgag ccaaaccgga actggtaaga ccctagcgta tctcctacca
     5221 agtcttctca gactacaaaa gaaaaaagcc caacaactct tgattctagc accaaacacg
     5281 gaacttgctg gacagatttt tgatgtatgt aaaacgtggg cagaagctat cggattgact
     5341 gctcaactct tcctttcagg ttcaagtcag aaacgacaaa ttgaacgtct taaaaagggg
     5401 ccagaaattc tgattggaac tcctggccgt atctttgaac tcattaaact taaaaaaatc
     5461 aagatgatga atgtggaaac catcatcctg gatgaatttg accaattact agatgattct
     5521 cagattcact ttgtagaaaa aatcactcac tacgcacctc gtgaccacca actggtctac
     5581 atgagtgcca cgaccaagtt tgaccaagaa aagattgtgc cgaatacacg cactattgat
     5641 ctctctgacc aaaaattgga caatatccag catttctaca tgcaggtaga ccaacgtcat
     5701 cgagtggata tgctacgaaa actggctcat gtagaggatt tccgtggtct agtcttcttc
     5761 aatagcctgt cagaccttgg gaatgccgag gaaaaactac agtatcgtga tatattgact
     5821 gtttccctcg ctagtgatgt taatgttaaa tttagaaaaa tcatcttaga aaagtttaaa
     5881 gataaccaac taaccctgct tcttgcaact gaccttttgg ctcgtggaat tgatatcgat
     5941 agcctagaat gtgtcgtaaa ctttgatatt cctagagata gcgaaaccta cacacaccgt
     6001 gctggtcgta ctggccgtat aggcaaggaa ggatatgtta ttactctcgt cactcatcca
     6061 gaagaaatca aaaaacttaa aaagtttgca agtatccgag aaattgtcct aaaaaaccaa
     6121 gaactctata tcaaataaag ccccattgct ctatacacat ccagtgtatg gagctttttt
     6181 ataagcaatt caattttata ctcatctgct ttcaaaaagc attctattcc atctccgatt
     6241 aacgatggac tttatcacct ccttctccag tccttgtatg acatcttgga gttgattcat
     6301 gacatcttcc aaagttcgaa aggctttatt cttaaatcca cgtttacgaa tctctttcca
     6361 cacttgttca atgggttcat ctctggtgtg tatggaggaa taaaggtaaa atcaatatta
     6421 gtcggaatct ttaaggtact tgatttatgc catatagcat tgtccataac gagtaaaaaa
     6481 taatcatctg gataagcttg tgaaagctct tctaaaaagg cgttcatcca ctcagtatta
     6541 catccaccag ctattaagaa aaatgattcg cctgtatggg catcaacagc tccataacaa
     6601 tagcgaaatt ctcgtatata gtgactatgg acatgtggac ctactcctat tggagaccaa
     6661 caagatccca gtttactgat tctaccgaaa ccagcctcat cttggtacat caagcgaacc
     6721 ttatgaaaag gtttactggt tttaaagcgc tttcttgtct tcttgaattg agattttatt
     6781 tttagacgcg acaatggttt gagcgtctgc tttcttagga tgttctggac gtggcgt
//
LOCUS       DAVBOG010000078         6818 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.079, whole genome shotgun sequence.
ACCESSION   DAVBOG010000078 DAVBOG010000000
VERSION     DAVBOG010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6818)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6818)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6818
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.079"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..390
                     /locus_tag="VQ865_002012"
     CDS             <1..390
                     /locus_tag="VQ865_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS630-like element IS630-Spn1 family
                     transposase"
                     /protein_id="HET3136299.1"
                     /translation="GQLIRGKVSGRRYQRISLVAGLTNGELIAPMTYEETMTSDFFEA
                     WFQNFLLPTLTTPSVIIMDNVRFHRMGKLELLCEEFGHKLLPLPPYSPEYNPIEKTWA
                     HIKKHLKKVLPSCNTFYEAFLSCSCFN"
     gene            451..1413
                     /locus_tag="VQ865_002013"
     CDS             451..1413
                     /locus_tag="VQ865_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsX-like permease family protein"
                     /protein_id="HET3136300.1"
                     /translation="MNMSNITIDGQEIDLSQTMPSYAQVVSLYDDTSISVSSNETDKV
                     LAGSLYTDTNEQGLTIPSSLLKNWNEQTGKNLTANDLIGKSVSASIVESAAETSKIAQ
                     FQTKIVRVINDEDDMEDSNSFMLSHQMETILKEAGFTKAVSYFILELKDPSQTKVVTE
                     ELQKNKKYTVLSQQRVLDIVITFIRVIQGLLIVLSSQAIVVAAVMIGIIIYINIMQRS
                     KEIGVMKAVGYQNRDVKGIFIYEAIWIVGIALLLAFLVAQGVGSLANAIVSHFYPSIT
                     KVFELNLLSVLGTLVFALLLGYVSAYFPARKISKMDPVEPLRYE"
     gene            1591..2598
                     /gene="gap"
                     /locus_tag="VQ865_002014"
     CDS             1591..2598
                     /gene="gap"
                     /locus_tag="VQ865_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008090210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HET3136301.1"
                     /translation="MVVKVGINGFGRIGRLAFRRIQNVEGVEVTRINDLTDPVMLAHL
                     LKYDTTQGRFDGTVEVKEGGFEVNGKFVKVSAERDPEQIDWATDGVEIVLEATGFFAK
                     KEAAEKHLKGGAKKVVITAPGGNDVKTVVFNTNHDVLDGTETVISGASCTTNCLAPMA
                     KALQDNFGVVEGLMTTIHAYTGDQMILDGPHRGGDLRRARAGAANIVPNSTGAAKAIG
                     LVIPELNGKLDGSAQRVPTPTGSVTELVAVLEKNVTVDEVNAAMKAASNESYGYTEDP
                     IVSSDIVGMSYGSLFDATQTKVLDVDGKQLVKVVSWYDNEMSYTAQLVRTLEYFAKIA
                     K"
     gene            complement(2665..3501)
                     /locus_tag="VQ865_002015"
     CDS             complement(2665..3501)
                     /locus_tag="VQ865_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HET3136302.1"
                     /translation="MTVKQLLEEQLLIPRKIRHFLRIKKHILINQEEVHWNEIVNPGD
                     VCQLTFDEEDYPQKTIPWGNPDLVQEVYQDQHLIIVNKPEGMKTHGNQPNEIALLNHV
                     STYVGQTCYVVHRLDMETSGLVLFAKNPFILPILNRLLEKKEISREYWALVDGNINRK
                     ELVFRDKIGRDRHDRRKRIVDAKNGQYAETHVSRLKQFSNKTSLAHCKLKTGRTHQIR
                     VHLLHHNLPILGDPLYNSKSKTSRLMLHAFRLSFTHPLTLERLTFTTLSNTFEKELKK
                     NG"
     gene            3627..5822
                     /locus_tag="VQ865_002016"
     CDS             3627..5822
                     /locus_tag="VQ865_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000762602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HET3136303.1"
                     /translation="MKLDKLFEKFLSLFKKETSELEDSDSTILRRSRSDRKKLAQVGP
                     IRKFWRRYHLTKIILILGLSAGLLVGIYLFAVAKSTNVNDLQNALKTRTLIFDREEKE
                     AGALSGQKGTYVDLTDISKNLQNAVIATEDRSFYKNDGINYGRFFLAIVTAGRSGGGS
                     TITQQLAKNAYLSQDQTVERKAKEFFLALELSKKYSKEQILTMYLNNAYFGNGVWGVE
                     DASKKYFGVSASEVSLDQAATLAGMLKGPELYNPLNSVEDSTNRRDTVLQNMVAAGYI
                     DKNQETEAAEVDMTSQLHDKYEGKISDYRYPSYFDAVVNEAVSKYNLTEEELVNNGYR
                     IYTELDQNYQANMQIVYENTSLFPRAEDGTFAQSGSVALEPKTGGVRGVVGQVADNDK
                     TGFRNFNYATQSKRSPGSTIKPLVVYTPAVEAGWALNKQLDNHTMQYDSYKVDNYAGI
                     KTSREVPMYQALAESLNLPAVATVNDLGVDKAFEAGEKFGLNMEKVDRVLGVALGSGV
                     ETNPLQMAQAYAAFANEGLMPEAHFISRIENASGQVIANHKNSQKRVIDKSVADKMTS
                     MMLGTFTNGTGISSSPADYVMAGKTGTTEAVFNPEYTSDQWVIGYTPDVVISHWLGFP
                     TTDENHYLAGSTSNGAAHVFRNIANTILPYTPGSTFTVENAYKQNGIAPANTKRQVQT
                     NDNSQTDDNLSDIRGRAQSLVDEASRAISDAKIKEKAQTIWDSIVNLFR"
     gene            5875..6027
                     /gene="rpmG"
                     /locus_tag="VQ865_002017"
     CDS             5875..6027
                     /gene="rpmG"
                     /locus_tag="VQ865_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015912025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HET3136304.1"
                     /translation="MALKKASLACAVCGSRNYSIKISGNPKPTRLEVNKFCKHCGKYT
                     THRETR"
     gene            6037..6213
                     /gene="secE"
                     /locus_tag="VQ865_002018"
     CDS             6037..6213
                     /gene="secE"
                     /locus_tag="VQ865_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001211016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HET3136305.1"
                     /translation="MRFIGDIFRLLKDTTWPTRKESWRDFRSIMEYTAFFVVIIYIFD
                     QLIVSGLIRFINIF"
     gene            6268..6804
                     /gene="nusG"
                     /locus_tag="VQ865_002019"
     CDS             6268..6804
                     /gene="nusG"
                     /locus_tag="VQ865_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HET3136306.1"
                     /translation="MDSFDKGWFVLQTYSGYENKVKENLLQRAQTYNMLDNILRVEIP
                     TQTVQVEKNGKRKEVEENRFPGYVLVEMVMTDEAWFVVRNTPNVTGFVGSHGNRSKPT
                     PLLEQEIRDILVSMGQTVQEFDFDVEIGQTVRIIDGAFADYTGKITEIDNNKVKMIIS
                     MFGNDTVAEVNLNQIAEL"
BASE COUNT         2120 a         1195 c         1473 g         2030 t
ORIGIN      
        1 ggtcagttaa taagaggcaa agtatctgga agaagatatc agaggatttc tttggttgca
       61 ggtctaacaa atggtgaatt aatcgctcca atgacttacg aagagacgat gacgagcgac
      121 ttttttgaag cttggtttca gaattttctc ttaccaacat taaccacacc atcggttatt
      181 attatggata atgtaagatt ccatagaatg gggaagctag aacttttatg cgaagagttt
      241 gggcataaac tgttacctct tcctccctac tcacctgagt acaatcctat tgagaaaaca
      301 tgggctcata tcaaaaagca cctcaaaaag gtattaccaa gttgcaatac cttttacgag
      361 gcttttttat cctgctcttg tttcaattga ctatatatca cggatacagt tgggaaagaa
      421 gctattaaat atttggagag tccttttggg atgaacatgt caaatattac tatagatggg
      481 caagaaatag atctgagtca aacgatgcct tcttatgctc aagtagtgag tctttatgat
      541 gatacaagta tctctgttag tagtaatgag acggacaaag tgttggctgg atccctctat
      601 actgatacaa atgaacaggg attaacgatt ccaagcagtt tactaaaaaa ttggaatgaa
      661 cagacaggaa aaaatttgac agctaatgat cttattggca aatcagtctc agccagcatt
      721 gtagaaagtg ctgccgaaac tagtaagatt gctcaatttc aaacgaagat tgtacgtgta
      781 atcaatgatg aagatgacat ggaggacagc aacagtttca tgctgtctca tcaaatggaa
      841 acgattttga aagaggctgg atttacgaaa gctgtatctt attttatctt ggaactcaaa
      901 gatccatcac agacaaaagt agtaacagaa gaattacaga aaaataagaa gtatactgtg
      961 ctttctcaac agagagttct tgatattgtg attaccttta ttcgtgttat tcagggatta
     1021 ttgattgtgc tttcatcaca agctattgtg gtagcagcgg ttatgattgg tatcattatt
     1081 tacatcaata tcatgcaacg ttctaaggaa ataggtgtca tgaaggcagt tggttatcag
     1141 aatcgtgatg tcaaaggaat ttttatttac gaggctatct ggattgtagg catcgccttg
     1201 ctgctggcat ttttggttgc acaaggggtg ggaagtttgg cgaatgcgat tgtaagtcac
     1261 ttttacccat ccatcactaa ggtttttgaa ttaaatcttt tatctgtttt aggaactcta
     1321 gttttcgctc tattacttgg ttatgtctca gcctacttcc cggcgcgtaa gattagtaaa
     1381 atggatcctg tagaaccgtt acgctatgaa tagtaaggga ttccttgatt tacagtctta
     1441 aaaaagaaac taacatagaa aaacaatggc catacttgca attcaactca aatagttgta
     1501 taataggttt gttgaaaggt gatttgtagt gattcaagtt actcttttca caataaaaat
     1561 ttcatgattt tcataaggag gaaatcacta atggtagtta aagttggtat taacggtttc
     1621 ggacgtatcg gtcgtcttgc tttccgtcgt atccaaaacg tagaaggtgt tgaagttaca
     1681 cgcatcaacg accttacaga tccagttatg cttgcacact tgttgaaata cgacacaact
     1741 caaggtcgtt tcgacggtac tgttgaagtt aaagaaggtg gatttgaagt taacggtaaa
     1801 ttcgttaaag tttctgctga acgtgatcca gagcaaatcg actgggctac tgacggtgta
     1861 gaaatcgttc ttgaagctac tggtttcttt gctaagaaag aagcagctga aaaacacctt
     1921 aaaggtggag ctaaaaaagt tgttatcact gctcctggtg gaaacgacgt taaaacagtt
     1981 gtattcaaca ctaaccacga cgttcttgac ggtactgaaa cagttatctc aggtgcttca
     2041 tgtactacaa actgcttggc tccaatggct aaagctcttc aagataactt tggtgttgtt
     2101 gaaggattga tgactactat ccacgcttac actggtgacc aaatgatcct tgacggacca
     2161 caccgtggtg gtgaccttcg ccgtgctcgc gctggtgctg caaacatcgt tcctaactca
     2221 actggtgctg ctaaagctat cggtcttgta atcccagaat tgaacggtaa acttgacgga
     2281 tctgcacaac gcgttccaac tccaactgga tcagttactg aattggtagc agttcttgaa
     2341 aagaacgtta ctgttgatga agtgaacgca gctatgaaag cagcttcaaa cgaatcatac
     2401 ggttacacag aagatccaat cgtatcttca gatatcgtag gtatgtctta cggttcattg
     2461 tttgacgcaa ctcaaactaa agttcttgac gttgacggta aacaattggt taaagttgta
     2521 tcatggtacg acaacgaaat gtcatacact gcacaacttg ttcgtactct tgaatacttc
     2581 gcaaaaattg ctaaataatt cttgagttga tagaaagcaa ggctttgtgg tcttgctttt
     2641 tatatagaaa aatggatgac acgatcatcc attctttttt aattcttttt caaatgtatt
     2701 tgaaagggta gtgaaagtta gcctctctaa agtaagtggg tgggtaaagg aaagtcggaa
     2761 ggcatgaagc ataagccggc ttgtctttga tttactatta tagagagggt ctcccaggat
     2821 aggaagatta tgatgcaaaa ggtgcacacg aatctgatgg gttcgccctg tctttagctt
     2881 gcaatgagcc aaggaagtct tgtttgagaa ttgctttaat ctgcttacat gcgtttcagc
     2941 atattgccca ttttttgcat caactattct ttttctacga tcatggcgat cacgtccaat
     3001 tttgtctctg aaaacaagtt cttttctgtt gatatttcca tcaactagag cccaatattc
     3061 tctagaaatc tcttttttct ccaataagcg attgagaatg ggcaggataa aaggattttt
     3121 ggcaaagaga actaagccac tggtttccat gtccagacga tgaacgacat agcaggtttg
     3181 gccaacatag gtactgacat ggttaagaag ggcaatttcg tttggttgat taccatgcgt
     3241 tttcatcccc tctggtttgt ttacaataat caagtgttga tcttgataaa cttcctgcac
     3301 taagtctggg ttgccccaag ggatcgtctt ttggggataa tcttcctcgt caaaagtcaa
     3361 ctggcaaaca tctccaggat ttacgatttc gttccagtgg acttcttctt gatttatcaa
     3421 aatatgtttc ttgattctca aaaaatgacg gatttttcta gggatgagga gttgttcctc
     3481 aagtaattgc tttaccgtca tttgaggtat agaggcgggt aatgtaaatg tgaattgcat
     3541 acagatattg taacaaaaaa agccctattt ggataggaaa tagctaaatt cttgtcttcc
     3601 tatgatgaag atgataaaat aaacgcatga aattagataa attatttgag aaatttcttt
     3661 ctctttttaa aaaagaaaca agtgaactag aggactctga ttctactatc ttacgtcgct
     3721 ctcgtagtga tcgaaaaaaa ttagcccaag taggtccgat tcgaaaattc tggcgtcgtt
     3781 atcatctaac aaagattatc cttatactag gtttgagtgc aggcttgcta gttggaatct
     3841 atttgtttgc tgtagccaag tcgaccaatg tcaatgattt gcaaaatgcc ttgaaaactc
     3901 ggactcttat ttttgaccgt gaagaaaaag aggctggtgc cttgtctggt caaaagggaa
     3961 cctatgttga tctgactgat atcagtaaaa acttgcagaa tgctgttatt gcgacagaag
     4021 accgttcttt ctataaaaat gacgggatta actatggccg tttcttcttg gctattgtca
     4081 ctgctggacg ttcaggtggt ggctctacca ttacccaaca gctggctaaa aacgcctatt
     4141 tatcacagga tcaaactgtt gagagaaaag cgaaagaatt tttccttgcc ttagaattaa
     4201 gcaaaaaata tagtaaggag caaattctaa ccatgtacct taacaacgct tattttggaa
     4261 atggtgtgtg gggtgtagaa gatgcgagta agaaatactt tggagtttct gcatcagaag
     4321 tgagtctgga tcaagctgcg actctggcag ggatgctcaa ggggccggaa ctgtataatc
     4381 ccttgaattc cgtagaagat tctactaatc ggcgcgatac tgtcttgcag aatatggttg
     4441 cagcaggata tattgataaa aaccaagaaa ccgaagctgc tgaagttgat atgacttcgc
     4501 aattgcacga taagtatgaa ggaaaaatct cagattaccg ttacccctct tattttgatg
     4561 cggtggttaa tgaagctgtt tccaagtata atctaacaga ggaagagctt gtcaataatg
     4621 gctaccgcat ttacacagag ctggaccaaa actaccaagc aaatatgcag attgtttatg
     4681 aaaacacatc gctatttccg agggcagagg atggaacgtt tgctcaatca ggaagtgtag
     4741 ctctcgaacc gaaaacaggg ggagttcgtg gagttgtcgg tcaagttgct gacaatgata
     4801 aaactggatt ccggaatttc aactatgcaa cccaatcaaa gcgtagtcct ggttctacaa
     4861 ttaagccttt agttgtttat acgccagcag ttgaagcagg ctgggctttg aataagcagt
     4921 tggataacca taccatgcag tatgacagct ataaggttga taactatgca gggatcaaaa
     4981 cgagtcgaga agttcctatg tatcaagcct tggcagaatc gcttaatcta cctgctgttg
     5041 ccactgttaa tgatttgggt gtcgacaagg cttttgaggc aggcgaaaaa ttcggactca
     5101 acatggaaaa ggtcgaccgt gttcttggtg tcgccttggg aagcggtgtt gaaaccaacc
     5161 ctcttcaaat ggctcaagca tacgctgcct ttgcaaatga aggtttaatg cctgaagctc
     5221 attttattag tagaattgaa aatgctagtg gacaagttat tgcgaatcat aaaaattcac
     5281 aaaaacgggt gattgataag tctgtagctg acaagatgac cagtatgatg ttggggactt
     5341 tcaccaacgg taccggtatt agttcatcgc ctgcagacta tgtcatggca gggaaaactg
     5401 gaacaactga agcagttttc aatccggagt acacaagtga ccagtgggta attggttata
     5461 ctccggatgt agtgattagc cactggcttg gctttccgac cactgatgaa aatcactatc
     5521 tagctggctc tacttcaaac ggtgcagctc atgtctttag aaacattgcc aataccattt
     5581 taccttatac gccaggaagt acctttacgg ttgaaaatgc ttataagcaa aatggaattg
     5641 caccagccaa tacaaaaaga caagtacaaa ccaatgataa tagccagaca gatgataatt
     5701 tgtctgatat tcgagggcgt gcgcaaagtc tagtagatga ggctagccgg gctatctcag
     5761 atgcgaagat taaggaaaag gctcaaacaa tatgggattc gatagtcaat ctatttcgct
     5821 aagatgcttg tcaaagccta gctttcttgt tataatggat aagatggagg cgttatggca
     5881 ctaaaaaaag caagcctagc ttgtgcggtt tgtggttcga gaaactattc aatcaagatc
     5941 agcggaaacc ccaagcctac acgactagaa gtaaataaat tttgtaagca ttgtggcaag
     6001 tacactacac acagagaaac gagataggag agagcgatgc gttttattgg agatattttt
     6061 agacttctta aagacacaac atggccaact cgcaaggaaa gctggagaga ttttcgttct
     6121 atcatggaat acacagcttt ctttgtagta attatttaca tttttgacca gttgattgtt
     6181 tcaggtttga ttcgatttat taacattttt tagaagatta gtggagttaa ttacactaga
     6241 aatcttctat ttatgaaagg aaatatcatg gatagttttg ataaaggatg gtttgtttta
     6301 caaacttatt ctggttatga aaataaggtg aaagaaaatc tattacaacg tgcacaaacc
     6361 tacaatatgt tggataatat tctacgcgtt gaaattccaa cacaaacagt gcaagttgaa
     6421 aaaaatggaa agagaaaaga agtagaagaa aatcgctttc caggttatgt tcttgtagaa
     6481 atggtcatga cagatgaagc ttggtttgtt gttcgaaaca caccaaatgt tacaggattt
     6541 gtcggatcac acgggaacag atcaaaacca actccattat tggaacaaga aattcgtgac
     6601 attttggtat ctatgggaca aactgttcaa gaatttgatt tcgatgttga gattggtcaa
     6661 actgtacgta ttattgatgg tgcttttgca gactacactg gtaagattac agaaattgat
     6721 aataacaaag tgaaaatgat tatctctatg tttggtaatg acacagttgc agaagtaaac
     6781 ctaaaccaaa tcgcagaatt ataatcctga gagaggct
//
LOCUS       DAVBOG010000079         6726 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.080, whole genome shotgun sequence.
ACCESSION   DAVBOG010000079 DAVBOG010000000
VERSION     DAVBOG010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6726
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.080"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            138..860
                     /locus_tag="VQ865_002020"
     CDS             138..860
                     /locus_tag="VQ865_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016397198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HET3136307.1"
                     /translation="MRLDKFLVACAVGSRTEVKNLLKAGRVTVNGKKEKSAKLQIDEK
                     IDEIRFDGQVLEYEEFVYYMMNKPKGVISATEDPKHRTVLDLLDDLARSKEVFPVGRL
                     DIDTHGLLLLTNDGQLAHVLLSPKRHVDKTYLAQVKGIMTQEDVETFAEGIPLKDFTC
                     QPAILELVSIDTEKNQSQIRVTIAEGKFHQIKRMVGYCGKEVVDLQRLTMGTLVLDEN
                     LERGEWRRLTKEELEILRANII"
     gene            1077..2411
                     /gene="pepC"
                     /locus_tag="VQ865_002021"
     CDS             1077..2411
                     /gene="pepC"
                     /locus_tag="VQ865_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase C"
                     /protein_id="HET3136308.1"
                     /translation="MNAIQESFTDKLFANYEANVKYQAIENAASHNGIFAALERRQSR
                     VDNTPVFSLDLTKDKVTNQKASGRCWMFAALNTFRHKLISQYKLENFELSQAHTFFWD
                     KYEKSNWFLEQVIATSDQELTSRKVSFLLQTPQQDGGQWDMVVSLFEKYGVVPKSVYP
                     ESVSSSSSRELNAVLNKLLRQDAQILRDLLVSGADQVTVQAKKEDLLQEIFNFLAMSL
                     GLPPRKFDFAYRDKDNNYKSEKGITPQEFYKKYVNLPLEDYVSVINAPTADKPYGKSY
                     TVEMLGNVVGSRAVRYINVPMERLKELAIAQMQAGETVWFGSDVGQLSNRKAGILATD
                     VYDFESSMDIKLTQDKAGRLDYSESLMTHAMVLTGVDLDENGKSTKWKVENSWGDKVG
                     TDGYFVASDAWMDEYTYQIVVRKELLTAEEQAAYGAEPIVLAPWDPMGALAE"
     gene            complement(2467..3378)
                     /locus_tag="VQ865_002022"
     CDS             complement(2467..3378)
                     /locus_tag="VQ865_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HET3136309.1"
                     /translation="MTEKLQLTKSDRKKVWWRSTFLQGSWNFERMQNLGWAYTLIPAI
                     KKLYTKKEDQIAALERHLEFFNTHPYVAAPVMGVTLALEEERANGVEIDDAAIQGVKI
                     GMMGPLAGIGDPVFWFTVRPILGSLGASLALTGNILGPLLFFVAWNLIRMSFLWYVQE
                     IGYKAGSEITKDMSGGILQDITKGASILGMFILAVLVQRWVNIKFAFDVSKVQLDEKA
                     YIHWDKLPEGSKGIQEAFAQVGQGLSQTPEKVTTFQQNLDMLIPGLSGLLLTLLCMYL
                     LKKKVSPITIILALFAVGIVAHVLHIM"
     gene            complement(3402..4205)
                     /locus_tag="VQ865_002023"
     CDS             complement(3402..4205)
                     /locus_tag="VQ865_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000022712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HET3136310.1"
                     /translation="MSIISMVLVVVVAFFAGLEGILDQFQFHQPLVACTLIGLVTGHL
                     EAGIILGGSLQMIALGWSNIGAAIAPDAALASVAAAIIMVLGGDFTKTGIGVAQAVAI
                     PLAVAGLFLTMIVRTISVGLVHTADAAAKKGDFGAVERAHFIALLFQGLRIALPAALL
                     LMVPTETVQSILSAMPDWLKDGMAIGGGMVVAVGYAMVINMMATREVWPFFALGFVLA
                     AVSDITLIGFGAIGVAIALIYLHLSKTGGNGGGGAATSNDPIGDILEDY"
     gene            complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ865_002024"
     CDS             complement(4233..5222)
                     /gene="manX"
                     /locus_tag="VQ865_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000021981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HET3136311.1"
                     /translation="MSIGIIIASHGEFAAGIHQSGSMIFGEQEKVQVVTFMPNEGPDD
                     LYAKFNNAVAAFDAEDEVLVLADLWSGSPFNQASRVMGENPERKFAIITGLNLPMLIQ
                     AYTERLMDAAAGVEKVAANIIKEAKDGIKALPEELNPVEEVASAAAAPVAQTAIPEGT
                     VIGDGKLKINLARLDTRLLHGQVATAWTPDSKANRIIVASDNVAKDDLRKELIKQAAP
                     GNVKANVVPIQKLIEISKDPRFGETHALILFETPQDALRAIEGGVPIKTLNVGSMAHS
                     TGKTLVNTVLSMDKEDVATFEKMRDLGVEFDVRKVPNDSKKDLFDLINKANVK"
     gene            complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ865_002025"
     CDS             complement(5455..6474)
                     /gene="adhP"
                     /locus_tag="VQ865_002025"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000649145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HET3136312.1"
                     /translation="MKAVVVNPESTGVAIEEKVLRPLETGEALVEVEYCGVCHTDLHV
                     AHGDFGQVPGRVLGHEGIGIVKEIAPDVKSLKVGDRVSVAWFFEGCGTCEYCTTGRET
                     LCRTVKNAGYSVDGGMAEQCIVTADYAVKVPDGLDPAQASSITCAGVTTYKAIKEAKI
                     EPGQWVVLYGAGGLGNLAVQYAKKVFNAHVIAVDINNDKLALAKEVGADIVINGLEVE
                     DVAGLIKEKTDGGAHSAVVTAVSKVAFNQAVDSIRAGGRVVAVGLPSEMMELSIVKTV
                     LDGIQVIGSLVGTRKDLEEAFQFGAEGLVVPVVQKRPVEDAVAIFDEMEKGQIQGRMV
                     LDFTH"
BASE COUNT         2017 a         1389 c         1478 g         1842 t
ORIGIN      
        1 agatagaact gacgaagtca gtaacatata tacggcaagg cgacgttgac gcggtttgaa
       61 gagatttttg aagagtatga aacgaaaagg aggttggtca ttgtactagc ctccttttga
      121 tatgatataa tagttctatg agattagata aatttttagt tgcctgtgcg gtgggaagtc
      181 ggactgaggt caaaaacttg ctcaaggctg ggcgcgtgac tgtaaatggt aaaaaagaaa
      241 aatcagctaa attgcagatt gatgaaaaaa tagatgagat tcgctttgat gggcaagtgt
      301 tggagtatga agagtttgtc tactacatga tgaacaagcc caaaggagtt atctcagcga
      361 ctgaggatcc caagcacaga accgttctgg acttgttgga tgacttggcg cggagtaagg
      421 aagttttccc agtaggacgc ttggatattg acacgcatgg tcttttgctc ttgaccaatg
      481 atggtcagct ggctcatgtt cttctttcgc ccaagcgtca tgtggacaag acttatctgg
      541 cacaagtcaa gggaatcatg acccaagaag atgtggagac atttgctgag ggtattcctc
      601 tcaaagactt tacctgtcaa cccgctatac tggagcttgt atccatagat acagaaaaga
      661 atcaaagcca aatccgtgtg accattgcag aagggaagtt tcatcagatc aagcgtatgg
      721 tgggctactg tggcaaggaa gtggtggact tgcaacgatt gactatggga actttagtat
      781 tagatgagaa cctggaacga ggggaatggc gtcgcttgac caaggaagaa ttagaaattc
      841 tccgcgctaa tattatttaa tttagtttaa tactcaatga aaatcaaaga gcaaactagg
      901 aaactagccg caggctgtac ttgagtacgg caaggcgacg ttgacgtggt ttgaagagat
      961 tttcgaagag tataaattcg aaaaaggtga gggacaatgt cctcgccttt tatgtttttt
     1021 agttgcttcc tttgtgaaaa gagttataat agactgtaga ataaaaggag gaatctatga
     1081 acgcgattca agaatcattt actgataaac tatttgccaa ctatgaagca aatgtaaaat
     1141 accaagcgat tgaaaatgct gccagccaca acggaatttt tgcagctctg gaacgtcgcc
     1201 aaagccgtgt agacaacaca cctgttttct cattggattt aaccaaggac aaggtcacta
     1261 accagaaagc gtctggtcgt tgctggatgt ttgcggctct caacaccttc cgccacaaac
     1321 tcatctcgca atacaaattg gagaactttg agttgtcaca agcccacact ttcttctggg
     1381 ataagtatga gaaatcaaac tggttcttgg agcaagtcat tgcgacttca gaccaagaat
     1441 tgactagccg caaggttagc ttcttactcc aaacacctca acaagatggc ggtcaatggg
     1501 atatggtcgt ttccctcttt gaaaaatacg gtgtcgtgcc taagtcagtt tatcctgagt
     1561 ctgtttcatc tagcagcagt cgtgagctaa atgcggtcct taataaattg cttcgtcaag
     1621 atgctcaaat cttgcgtgat ttgcttgttt ctggtgcaga tcaagtgact gttcaagcta
     1681 agaaagaaga cctcttgcaa gaaatcttta actttcttgc tatgtcatta ggacttccac
     1741 cacgcaagtt tgactttgct tatcgcgata aagataacaa ctacaaaagt gaaaaaggaa
     1801 tcacaccaca agagttctac aagaaatatg tcaatcttcc tttagaagac tacgtttctg
     1861 ttatcaatgc tccaactgct gataaacctt acggaaaatc ttacacagtt gagatgttgg
     1921 ggaatgtggt tggtagccgt gcagttcgtt acatcaacgt tccaatggag cgcttgaaag
     1981 aattggcgat tgcccaaatg caagcaggtg agactgtttg gtttggttct gatgtcggcc
     2041 agctcagtaa ccgtaaggct ggaatccttg cgacagatgt ttatgacttt gaatcaagca
     2101 tggacattaa acttactcaa gacaaggctg gacgtttgga ctatagcgaa agcttgatga
     2161 cccacgccat ggtcttgaca ggtgttgact tggacgaaaa tggtaaatca accaagtgga
     2221 aggttgaaaa ctcatgggga gacaaggtcg gtacagatgg ttactttgtt gcctcagacg
     2281 cttggatgga cgaatacaca taccaaatcg ttgttcgtaa ggaattgctg acagcagaag
     2341 aacaagctgc ctatggagca gaaccaattg tacttgcacc atgggatcca atgggagcct
     2401 tggctgaata aaagcataga aaaaaggaat cagattttag aacctggttc ctttttagtt
     2461 gcttgattac atgatgtgaa gaacatgtgc cacaataccc actgcgaaga gagcaaggat
     2521 aatagtgatt ggagatactt ttttcttaag taagtacatg caaagtaaag taaggagtag
     2581 tcctgataat ccaggaatca acatatccaa gttttgttgg aaagtagtaa ctttttcagg
     2641 agtttgagac aatccttgtc ctacttgtgc gaatgcttct tggatacctt tagacccttc
     2701 tggcaattta tcccaatgga tataagcctt ttcatctagt tgaactttag aaacatcgaa
     2761 agcaaattta atatttaccc agcgttgaac aaggacagca agaatgaaca tcccaaggat
     2821 agaagctcct ttagtgatat cttgaaggat accaccagac atatctttag tgatttctga
     2881 tccagcctta tatccaatct cttgaacata ccacaagaat gacatacgaa tcaagttcca
     2941 tgcaacaaag aagaggagtg gacccaagat attgccagta agggcaagtg aagcaccgag
     3001 agatccaagg attgggcgca ctgtaaacca gaatactggg tcaccgatac cagcaagagg
     3061 tcccatcata ccgattttaa ccccttggat agcagcgtca tcgatttcca caccgttagc
     3121 acgttcttct tcaagcgcaa gagtaacccc catgactgga gcagctacgt atggatgagt
     3181 gttgaagaac tcaaggtgac gctcaagagc agcgatttga tcttcttttt tagtatagag
     3241 ttttttgata gctggaatga gtgtataagc ccagcccaag ttttgcatcc gttcaaagtt
     3301 ccaagaccct tgtaagaagg ttgaacgcca ccaaactttt ttacgatctg atttagttaa
     3361 ttgaagtttt tcagtcatga tgttttcagt cctttcttat cttagtagtc ttctaggata
     3421 tcgccgattg ggtcgttaga agttgcggct cctccgccac catttccacc agttttagaa
     3481 aggtgaaggt agataagagc gatagcaacg ccgatagcac cgaatccgat tagagtaata
     3541 tctgacacag cagcgagaac gaaaccaaga gcgaagaatg gccatacttc acgagttgcc
     3601 atcatgttga taaccatggc gtaaccaacg gcaacgacca taccaccacc gatagccata
     3661 ccatctttga gccagtctgg catggcacta aggatacttt gtacagtttc agttggtacc
     3721 ataaggagaa gagctgcagg aagcgcgata cgaagtcctt ggaaaagtag cgcgatgaaa
     3781 tgcgcacgct ccacagcgcc gaagtcacct tttttagcgg cagcatctgc agtatgaacc
     3841 aaaccaactg aaattgtacg aacaatcatt gtcaagaaaa gtccagctac agcaagaggg
     3901 atagcaaccg cttgggcaac accgatacca gtcttggtaa agtcaccacc aagaaccatg
     3961 ataatggcag cagcgacaga agcaagtgca gcatcaggag cgatagcagc accgatattt
     4021 gaccaaccaa gggcaatcat ttgaagcgat ccaccgagga taatccctgc ttccaagtga
     4081 cctgttacaa gcccaataag ggtacaggct acaagtggtt ggtgaaattg gaactggtcg
     4141 aggatgcctt caagacctgc aaagaaggct acaacgacta ctaaaaccat agaaataata
     4201 gacatgttta aaatcctttc ataaataatg gcttatttga cattggcttt gttaatcaag
     4261 tcaaacaaat cttttttaga atcatttggt actttacgga catcaaattc aacacccaag
     4321 tcacgcattt tttcaaatgt agcaacgtct tctttgtcca tagacaaaac ggtattgacc
     4381 aatgttttac ctgttgagtg agccatagaa ccaacattaa gagtcttgat tggcacgccg
     4441 ccttcgatgg cacgaagggc atcttgaggt gtttcaaaca agataagggc atgtgtttct
     4501 ccaaaacgtg ggtcttttga aatctcaatc agtttttgaa ttggaaccac gttagccttg
     4561 acattacctg gagctgcttg tttaatcaat tctttacgaa ggtcgtcttt agccacgtta
     4621 tctgaagcaa cgatgatacg atttgctttt gaatctggag tccaagcagt tgcaacctga
     4681 ccgtgaagta gacgtgtgtc aagacgggca agattgattt tcaatttacc gtctccgata
     4741 acagttcctt ctgggatagc agtttgggca actggagcag ctgcagcgct tgcaacttct
     4801 tcgactggat ttagctcttc tggaagagct ttgatgccat ctttggcttc tttaatgata
     4861 ttagcagcga ctttttctac acctgcagca gcgtccatga ggcgctctgt gtaggcttga
     4921 atcaacatcg gtaagttaag tcctgtgatg atggcaaact tacgctcagg attttctccc
     4981 atcacgcgac tagcttggtt aaatggagaa ccactccaaa ggtcagccaa aactagaacc
     5041 tcatcttctg cgtcaaatgc agcaacagcg ttattaaact tagcgtatag atcatcagga
     5101 ccttcatttg gcataaaggt cacaacttga accttttctt gttcaccaaa gatcatagat
     5161 cctgactgat gaatacccgc agcaaattcg ccgtggctcg caataatgat tccgatactc
     5221 attattgtca ttcctccttt tttgttttag ttttcattta agaaaacttt aagactgttt
     5281 aagtataaac cgttttcata aaaaaagcaa ctatttatca taaaaaatta aaaaattttt
     5341 atttttgtat gttgacatgt tgagtttttg aggagtaatc ttgaattctt atttaaaatt
     5401 taatataaaa aagttggaag aagcttccaa cttttaaaat aggtttctat tagattagtg
     5461 ggtgaagtcg agtaccatac gtccttggat ttggcctttt tccatttcgt cgaaaatggc
     5521 aacagcatct tctactggac gtttttgaac aactgggact accagacctt ctgcaccaaa
     5581 ttggaaggct tcttctaagt ctttacgagt tccgacaaga gaaccgatga cttggattcc
     5641 atcgaggact gttttaacga tgctgagttc catcatttca gaaggaagac caacagcgac
     5701 gacgcgacca ccagcacgaa tggagtcaac agcctggttg aaggcaactt tagacacagc
     5761 agttacgaca gctgaatgag ctcctccatc agttttttct ttaatgagtc cagctacatc
     5821 ttcaacttcg aggccgttaa tcacaatgtc agcgcctact tcttttgcaa gggcaagttt
     5881 gtcattgttg atatcgactg cgataacatg agcattgaat acttttttag cgtattgaac
     5941 agcgaggtta ccaagtccac cagcaccgta aagaacaacc cattggcctg gttcaatttt
     6001 tgcttctttg atagctttat aggttgttac tccagcacat gtgatagaag aagcttgggc
     6061 tggatcaagt ccgtcaggaa ctttgacagc atagtcagca gttacgatac attgttcagc
     6121 cataccaccg tctactgagt agccagcatt tttcactgta cggcaaaggg tttcgcgacc
     6181 agttgtacag tattcgcaag tgccacatcc ttcaaagaac caagcaacgc tgacgcggtc
     6241 accgacttta aggcttttca catctggagc aatctcttta acgataccga taccttcgtg
     6301 cccaagaaca cgtcctggga cttgaccaaa gtcaccatga gcaacgtgga ggtcggtgtg
     6361 gcaaacacca cagtattcaa cttctacaag tgcttcccca gtttcaagtg gacggagtac
     6421 tttttcttca atagcaacac cagtgctttc tggatttaca acaacagctt tcatagctat
     6481 cctccttgat attgaccgag aacagggaca acgggactgg attgattttt tgtcaacaga
     6541 gtcgagtgtg acgagctctc ttgtatttat atgtgaagta tatcacaaaa gaaagccttt
     6601 tccaaggttt tggagacaaa aagtagaaca atcgattaac tggttgatga gactgtgaaa
     6661 agagcacaaa gaccagcttg caagctggtc atactcttcg aaaatctctt caaaccacgt
     6721 cagctt
//
LOCUS       DAVBOG010000080         6627 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.081, whole genome shotgun sequence.
ACCESSION   DAVBOG010000080 DAVBOG010000000
VERSION     DAVBOG010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6627)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6627)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6627
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.081"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            170..370
                     /locus_tag="VQ865_002026"
     CDS             170..370
                     /locus_tag="VQ865_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000226586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136313.1"
                     /translation="MVASASASSTSTQAQEQVDKSELRALSQELDQRLKALATVSDQK
                     IDATKAVLLDAQKAPEDSALTE"
     gene            412..816
                     /locus_tag="VQ865_002027"
     CDS             412..816
                     /locus_tag="VQ865_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000377663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136314.1"
                     /translation="MDSLKDVKANASDSKPAQDKKDAKQGTEDSKDSDKMTETNSVPA
                     GVIVVSLLALLGVIAFWLIRRKKESEIQQLSTELIKVLGQLDAEKADKKVLAKAQNLL
                     QETLDFVKEENGSAETETKLVEELKAILDKLK"
     gene            1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ865_002028"
     CDS             1047..1754
                     /gene="ccdA2"
                     /locus_tag="VQ865_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004237834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     membrane protein CcdA2"
                     /protein_id="HET3136315.1"
                     /translation="METIVFLISVFLAGVLSFFSPCIFPLLPVYAGILLDDQESAKSF
                     SLFGRKVLWSGLIRTLCFIAGISLIFFILGFGAGYFGHILYANWFRYGMGAIIIILGL
                     HQMEIFHLKKLEVQKSFTFKKSDSNRYWSAFLLGITFSFGWTPCIGPVLSSVLALAAS
                     GGNGAWQGAIYTLIYTLGMALPFLVLALASGLVMPYFSKIKRHMMLLKKIGGFLIVLM
                     GILLLLGQVNVLAGIFE"
     gene            1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ865_002029"
     CDS             1765..2322
                     /gene="sdbB"
                     /locus_tag="VQ865_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol-disulfide oxidoreductase-associated
                     lipoprotein SdbB"
                     /protein_id="HET3136316.1"
                     /translation="MKKVMFAGLSLLSLVVLMACGEEETKKTQAAQQPKQQTTVQQIA
                     VGKDASNFTLQSMDGKEVKLSDFKGKKVYLKFWASWCGPCKKSMPELMELAAKPDRDF
                     EILTVIAPGIQGEKTVEQFPQWFQEQGYKDIPVLYDTKATTFQAYQIRSIPTEYLIDS
                     QGKIGKIQFGAISNADAETAFKEMN"
     gene            2697..4088
                     /locus_tag="VQ865_002030"
     CDS             2697..4088
                     /locus_tag="VQ865_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001020339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HET3136317.1"
                     /translation="MNIFRTKNVSLDKTEMHRHLKLWDLILLGIGAMVGTGVFTITGT
                     AAATLAGPALVISIVISALCVGLSALFFAEFASRVPATGGAYSYLYAILGEFPAWLAG
                     WLTMMEFMTAISGVASGWAAYFKGLLSQYGIALPQALNGTFNPQAGTFVDLLPILVLV
                     LVTSLVLLNAKAALRFNSILVILKFSALALFVLVGIWNIKFDNWSNFAPYGFGQIYGA
                     STGIIAGASLMFFGFLGFESISMAVDEVKTPQKNIPRGIVLSLSIVTILYALVTLVLT
                     GVVHYSHLNVDDAVAFALRSVGISWAANYVSLVAILTLITVCISMTYALSRMIYSLAR
                     DGLVPAAFKELTKTSKIPKNATILTGLASAVAAGMFPLASIAAFLNICTLAYLILLAY
                     GLIRLRKEKGMPKAGEFKTPLVPLLPILSIIICLSFMLQYNMNTWIAFLVALLVGSII
                     YFTYGYKHSTIEE"
     gene            4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ865_002031"
     CDS             4231..5148
                     /gene="adcAII"
                     /locus_tag="VQ865_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000744528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding lipoprotein AdcAII"
                     /protein_id="HET3136318.1"
                     /translation="MKKQNLFLVLLSVFLLCLGACGQKESQTGKGMKIVTSFYPIYAM
                     VKEVSGDLNDVRMIQSSSGIHSFEPSANDIAAIYDSDVFVYHSHTLESWAGSLDPNLK
                     KSKVKVLEASEGMTLERVPGLEDVEAGDGVDEKTLYDPHTWLDPEKAGEEAQIIADKL
                     SEVDSEHKETYQKNAQAFIKKAQELTKKFQPKFEKATQKTFVTQHTAFSYLAKRFGLN
                     QLGIAGISPEQEPSPRQLTEIQEFVKTYKVKTIFTESNASSKVAETLVKSTGVGLKTL
                     NPLEADPQNDKTYLENLEENMSVLAEELK"
     gene            5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ865_002032"
     CDS             5156..>6627
                     /gene="phtB"
                     /locus_tag="VQ865_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3136319.1"
                     /translation="MKINKKYVAGSVAVLALSVCSYELGRYQAGQDKKESNRVAYIDG
                     DQAGQKAENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISE
                     ELLMKDPNYQLKDSDIVNEIKGGYVIKVNGKYYVYLKDAAHADNIRTKEEIKRQKQEH
                     SHNHGGGSNDQAVVAARAQGRYTTDDGYIFNASDIIEDTGDAYIVPHGNHFHYIPKSD
                     LSASELAAAQAYWNGKQGSRPSSSSSHNANPAQPRLSENHNLTVTPTYHQNQGENISS
                     LLRELYAKPLSERHVESDGLIFDPAQITSRTARGVAVPHGNHYHFIPYEQMSELEKRI
                     ARIIPLRYRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPSNPIDEKLVKEAVRKVGDGY
                     VFEENGVSRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYD
                     LLARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT         2032 a         1215 c         1411 g         1969 t
ORIGIN      
        1 gtaaaatgaa ataagaacag gacaaatcga tcaggacagt aaaatcgaat tctaacaatg
       61 ttttagaagt ccatatgtac tattctagtt tcaatatatc ataactgttc ctagtcaacc
      121 tgcaagccct atcccagctc caagctcagc tccgactcaa gatcctagag tggtagcaag
      181 cgcttcggct agctcaacga gcacacaagc tcaagagcaa gttgacaagt ctgaacttcg
      241 tgccttgagt caagagctag accaacgctt gaaagctttg gcaacagtat ctgatcagaa
      301 aatcgatgca accaaggctg tcctcctaga tgctcaaaaa gctccggaag atagtgcctt
      361 gacagagtaa ggtctgcata ctgcagtaga gtctgtgaag gctgggctgc cttggactct
      421 ctcaaagatg tgaaagcaaa tgctagcgac agcaagcctg cacaggacaa gaaggatgca
      481 aaacaaggaa cggaagatag taaggattca gataagatga ctgaaacaaa ctcagttccg
      541 gcaggagtga ttgtggtcag tctacttgcc ctcctaggcg tgattgcctt ctggctgatt
      601 cgccgtaaga aagagtcaga aatccagcaa ttaagcacgg aattgatcaa ggttctagga
      661 cagctagatg cagaaaaagc ggataaaaaa gtccttgcca aagcccaaaa ccttctccaa
      721 gaaacccttg atttcgtgaa agaagaaaat ggctcagcag agacagaaac taaactagta
      781 gaggagctta aagcaatcct tgacaaactc aagtaaaaca tgatttatga aatgtcagac
      841 ctaaaagaca ttttcgttca caaaagcagc gatgagtaat ccttgtcgtt gctttttggc
      901 tattttgggg gataagatcc gccttgacta gcaaaagaaa agattggtcc aatagtgccc
      961 gatacgattt tgcgtagcag aaagcttaca aataaaattg aatatagtaa aataggatta
     1021 gaattattaa gaaagttggt tctttattgg aaacgatagt atttttaatc tctgtttttc
     1081 tagcaggtgt tttatccttt ttttctcctt gtatttttcc tcttctgcca gtctatgctg
     1141 ggattttatt ggatgatcaa gaaagtgcaa aaagcttttc tttgtttggg agaaaggttc
     1201 tctggtcagg cttgattcga acactttgct ttatcgctgg tatctctctc attttcttta
     1261 ttctaggctt tggtgctggt tactttggtc atattctcta tgcaaattgg tttcgatatg
     1321 gcatgggagc tattattatc attttgggtc ttcaccagat ggaaattttt catttgaaga
     1381 aattagaagt tcaaaaaagt tttaccttta aaaaatcaga ttctaatcgt tattggtcag
     1441 cttttttact tggtattacc tttagctttg gttggacacc ttgtattggt ccagttttaa
     1501 gttctgtttt agcacttgcg gcttctggag gcaatggcgc ttggcaagga gcgatttata
     1561 ctctcattta cactctgggc atggcccttc ctttcttggt attggcacta gcttcaggtc
     1621 tagtcatgcc atattttagt aaaatcaagc gtcatatgat gctactaaag aaaattggtg
     1681 gtttcctcat tgttttaatg ggaattttgt tactattagg acaagtaaat gttctagctg
     1741 gaatttttga ataaaggagg acaaatgaaa aaagtaatgt ttgctggctt aagtctcttg
     1801 tcattagttg tattgatggc ctgtggtgag gaagaaacta aaaagactca agcagcacaa
     1861 cagccaaaac aacaaacgac tgtacaacaa attgctgttg gaaaagatgc ttcaaacttc
     1921 acattgcaat ccatggatgg caaagaagtt aagttatctg attttaaggg taaaaaggtt
     1981 tacttgaagt tttgggcttc atggtgcggt ccatgcaaga aaagtatgcc agagttgatg
     2041 gaactagcgg cgaaaccaga tcgtgatttc gaaattctta ctgtcattgc accaggaatt
     2101 caaggtgaaa aaactgttga gcaattccca caatggttcc aggaacaagg atataaggat
     2161 atcccagttc tttatgatac caaagcaacc accttccaag cttatcaaat tcgaagcatt
     2221 cctacagaat atttaattga tagccaagga aagattggaa agattcaatt tggtgctatc
     2281 agtaatgcgg atgcagaaac agcatttaaa gaaatgaact agaatcgata aaatctgatt
     2341 acaagatgta gtcagatttt ggtaacttct aaaactaact tccagtttcc cacaacctag
     2401 cttttagtat gagaaaaacg cgtgacatca gtggaaatcc gtcttagact aacttccact
     2461 ggttttcttt ttcttgatat ataagggttc aaaagcgaaa agactcagaa aaaagtgcac
     2521 gacaaatagc cctaaaacag agtcgtttta gagtaacttc cagttttggg agagagatgg
     2581 aagttacttt gagaagttac ggtagtcaga tttttttaga aaaacatttt ataaatattc
     2641 acatatctcc tatatttatg gtaaaataga atcatcagtt tattttggag tcaaagatga
     2701 atatatttag aacaaagaat gttagtttag ataaaacaga gatgcatagg catttgaagt
     2761 tatgggattt gattttgctg ggtattggag ccatggtagg gacaggtgtc tttacaatca
     2821 caggtactgc agctgctaca cttgctggtc cagcactagt gatttcaatc gttatttctg
     2881 ccttgtgtgt gggattatca gccctctttt ttgcagaatt tgcctcgcga gtacccgcta
     2941 caggaggtgc ctatagttac ctctatgcta tcttaggaga attccctgcc tggttggctg
     3001 gttggttaac catgatggag ttcatgacag ccatatcagg cgtagcttcg ggttgggcag
     3061 cttattttaa aggcttgctc tctcaatacg ggatagccct tcctcaggct ttaaatggta
     3121 cctttaatcc tcaagcaggg acatttgttg atttattgcc tattcttgtc ttggtcttgg
     3181 tgacttcgct tgttttacta aatgccaagg cagccttacg ctttaattcg attctagtta
     3241 ttttgaaatt ttccgcttta gctctctttg ttttagtagg aatttggaat attaagtttg
     3301 ataattggag caattttgct ccttacggtt ttggacaaat ctatggagct agtactggta
     3361 ttatagctgg tgcgtccttg atgttcttcg gttttttggg atttgaatcc atctctatgg
     3421 ctgtagatga agtcaagact cctcaaaaaa atattcctag agggattgtc ttatcgcttt
     3481 ctatcgtaac cattctctat gccttggtga cccttgtttt gactggtgtg gttcactata
     3541 gtcatttaaa tgtcgatgat gccgttgcct ttgcccttcg tagtgttggg attagttggg
     3601 cagccaacta tgtgtcatta gtggctatct tgaccttgat tacagtttgt atttcgatga
     3661 cctatgccct atcgcgtatg atttacagtt tagcacgtga tggcttagtg cctgctgcct
     3721 ttaaggaact gacgaagact agcaagatac caaagaatgc tactatcttg acaggtctag
     3781 cttcagcagt agcagcagga atgttcccgc tagccagtat tgcagccttt ttaaatattt
     3841 gtaccttagc ctacttgatc ctgctggctt atggtctgat tcgcttacgg aaagaaaaag
     3901 gaatgcccaa agctggggaa tttaaaacac cattggtacc tctgttacca attttatcga
     3961 tcatcatttg tttatccttc atgttacagt ataatatgaa tacctggatt gctttcctag
     4021 ttgcgttgtt agtaggaagt attatttact tcacttatgg ctataagcat tctaccatag
     4081 aagaataaag tgaaagtcta ttgagttgtt gacactcagt agatttttat atgtgaaaga
     4141 aatttcaaat tttttctaaa aatatcttga cagattaaat tttcaggagt agaatattta
     4201 ctagttaatt aaatggttaa ggagttgttc atgaagaaac aaaatttatt tttagtcctg
     4261 ttaagtgtct ttcttttgtg cttgggggct tgtggtcaaa aggaaagtca gacaggaaag
     4321 gggatgaaaa ttgtgaccag tttttatcct atctacgcta tggttaagga agtatctggt
     4381 gacttgaatg atgttcggat gattcagtca agtagtggta ttcactcctt tgaaccttcg
     4441 gcaaatgata tcgcagccat ctatgattca gatgtctttg tttaccattc tcatacactc
     4501 gaatcttggg caggaagtct ggatccaaat ctaaaaaaat ccaaagtgaa ggtcttagag
     4561 gcttctgagg gaatgacctt ggaacgtgtc cctggactag aggatgtgga agcaggggat
     4621 ggagttgatg aaaaaacgct ctatgaccct cacacatggc tagatcctga aaaagctgga
     4681 gaagaagccc aaattatcgc tgataaactt tcagaggtgg atagtgagca taaagagact
     4741 tatcagaaaa atgcgcaagc ctttatcaaa aaagctcagg aattgactaa gaaattccaa
     4801 ccaaaatttg aaaaagcgac tcagaaaaca tttgtaacac aacatacagc cttttcttat
     4861 ctagcgaaga gatttgggct taatcaactt ggtattgcag gcatctctcc tgaacaagaa
     4921 ccaagtccac gacaattaac agaaattcag gaatttgtta aaacctataa ggttaaaacg
     4981 atttttacag aaagtaatgc ttcttcaaaa gtagctgaaa ctcttgtcaa atcaacaggt
     5041 gtgggtctta aaactctgaa tcctttagag gcagacccac aaaatgacaa gacctattta
     5101 gaaaatctgg aagaaaatat gagtgttcta gcagaagaat taaagtgagg aaagaatgaa
     5161 aatcaataaa aaatatgtag caggttcagt ggcagttctt gccctaagtg tttgttccta
     5221 tgaacttggg cgttaccaag ctggtcagga taagaaagag tctaatcgag ttgcttatat
     5281 agatggtgat caggctggtc aaaaggcaga aaatttgaca ccagatgaag tcagtaagag
     5341 ggaggggatc aacgccgaac aaatcgtcat caagattacg gatcaaggtt atgtgacctc
     5401 tcatggagac cattatcatt actataatgg caaggtccct tatgatgcca tcatcagtga
     5461 agagctcctc atgaaagatc cgaattatca gttgaaggat tcagacattg tcaatgaaat
     5521 caagggtggt tatgtcatta aggtaaacgg taaatactat gtttacctta aggatgcagc
     5581 tcatgcggat aatattcgga caaaagaaga gattaaacgt cagaagcagg aacacagtca
     5641 taatcacggg ggtggttcta acgatcaagc agtagttgca gccagagccc aaggacgcta
     5701 caccacagat gatgggtata tcttcaatgc atctgatatc attgaggaca cgggtgatgc
     5761 ttatattgtc cctcacggca atcacttcca ctatattcct aagagtgatt tgtctgccag
     5821 tgaattagct gctgcccaag cctattggaa tgggaagcag ggatctcgtc cttcttcaag
     5881 ttctagtcat aatgcaaatc cagctcaacc aagattgtca gagaaccaca atctgactgt
     5941 cactccaact tatcatcaaa atcaagggga aaacatttca agccttttac gtgaattgta
     6001 tgctaaaccc ttatcagaac gccatgtgga atctgatggc cttattttcg acccagcgca
     6061 aatcacaagt cgaaccgcca gaggtgtagc tgtccctcat ggtaaccatt accactttat
     6121 cccttatgaa caaatgtctg aattggaaaa acgaattgct cgtattattc cccttcgtta
     6181 tcgttcaaac cattgggtac cagattcaag accagaacaa ccaagtccac aaccgactcc
     6241 agaacctagt ccaagtccgc aaccagctcc aagcaatcca attgatgaga aattggtcaa
     6301 agaagctgtt cgaaaagtag gcgatggtta tgtctttgag gagaatggag tttctcgtta
     6361 tatcccagcc aaggatcttt cagcagaaac agcagcaggc attgatagca aactggccaa
     6421 gcaggaaagt ttatctcata agctaggagc taagaaaacc gacctcccat ctagtgatag
     6481 agaattttac aataaggctt atgacttact agcaagaatt caccaagatt tacttgataa
     6541 taaaggtcga caagttgatt ttgaggcttt ggataacctg ttggaacgac tcaaggatgt
     6601 ctcaagtgat aaagtcaagt tagtgga
//
LOCUS       DAVBOG010000081         6206 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.082, whole genome shotgun sequence.
ACCESSION   DAVBOG010000081 DAVBOG010000000
VERSION     DAVBOG010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 6206)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6206)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6206
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.082"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(482..707)
                     /locus_tag="VQ865_002033"
                     /pseudo
     CDS             complement(482..707)
                     /locus_tag="VQ865_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001824185.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            1555..2427
                     /locus_tag="VQ865_002034"
     CDS             1555..2427
                     /locus_tag="VQ865_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4300 family protein"
                     /protein_id="HET3136320.1"
                     /translation="MKKSRKLATLGICSALFLGLAACQQQHATSEGTNQRQSSSAKVP
                     WKASYTNLNNQVSTEEVKSLLSAHLDPNSVDAFFNLVNDYNTIVGSTGLSGDFTSFTH
                     TEYDVEKISHLWNQKKGDFVGTNCRINSYCLLKNSVTIPKLEKNDQLLFLDNDAIDKG
                     KVFDSQDKEEFDILFSRVPTEATTDVKVHAEKMETFFSQFQFNEKARMLSVVLHDNLD
                     GEYLFVGHVGVLVPADDGFLFVEKLTFEEPYQAIKFASKEDCYKYLGTKYADYTGEGL
                     AKPFIMDNDKWVKL"
     gene            complement(2573..2917)
                     /locus_tag="VQ865_002035"
                     /pseudo
     CDS             complement(2573..2917)
                     /locus_tag="VQ865_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
     gene            3060..3372
                     /locus_tag="VQ865_002036"
                     /pseudo
     CDS             3060..3372
                     /locus_tag="VQ865_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007521917.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            3376..4092
                     /locus_tag="VQ865_002037"
     CDS             3376..4092
                     /locus_tag="VQ865_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HET3136321.1"
                     /translation="MKKYFIGGLGSNAYHSKDFLQELDSQVYFLNPYEKHLRDETELK
                     SWFKNEIVEEESICLIGHSIGGDLARYFASEFEEVKKLILLDGGYLDLDKILPLDTEL
                     EETKNYIKSQIISDLDVLTSKEKSEAKHWSENMEKAVRQSYHWNVEYNRYELAINYEN
                     IEAILRLRRKIQAFKREVGDTLFISPRYPNEATWREEALKELPDYFDTIFLENFGHEL
                     YTQAPKEIASLMNEWLAYFL"
     gene            complement(4222..5037)
                     /locus_tag="VQ865_002038"
     CDS             complement(4222..5037)
                     /locus_tag="VQ865_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HET3136322.1"
                     /translation="MIRFLVLAGYFELTIYLHLSGKLNQYINMHYSYLAYISMVLSFI
                     LAIVQLYIWMKQVKTHSHLNSRLAKMTSISLLAIPLVIGLTFPTVSLDSQTVSAKGYH
                     FPLSEGTDLAIQTSEGTTSQYLKPDTSSYFSKSAYEKEMRTAADKYLSQDSIQITNEN
                     YMEVMEAIYDYPDEFEGKTIQFTGFVYNDPSHANSQFLFRFGIIHCIADSGVYGLLTK
                     GNTRQYENNTWISAKGKLVNHYHKELKQNLPTLEIDSFTKVDKPENPYVYRAF"
     gene            complement(5034..5939)
                     /locus_tag="VQ865_002039"
     CDS             complement(5034..5939)
                     /locus_tag="VQ865_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HET3136323.1"
                     /translation="MTAFQQLPSSVLQTGAIFLSIIIEALPFVLIGSIVSGLIEVYIT
                     PDKVYHFLPRNRWGRIFFGTFVGMFFPSCECGIVPIINRFLEKKVPSYTAVPFLVTAP
                     VINPIVLFATYSAFGNSFHVALLRALGSILVAVILGIFLGFFWQEPIQKENRLACHEH
                     DFSYLSSAKKVFQVFVQAIDEFFDTGRYLVFGCLFASIIQVYVPTRILTSISATPLFA
                     ILLLMILAFLLSLCSEADAFIGASLLSSFGLAPVLAFLVIGPMLDIKNILMMKNYLKA
                     RFISHFITIVTLVVLVYSLLIGVIL"
BASE COUNT         1961 a         1073 c         1249 g         1923 t
ORIGIN      
        1 aaataagata tgtacaaatt gattagaaag tcaaatgaat ttctacaaat gttttagtaa
       61 tcgcaatcta cttgtctaga ttcgatctga tatattttcg atttaatgat atggtattta
      121 aaacctccaa agtagcttgc tccattcttt tacttacgtg agtgtagatg ttatttactg
      181 ttttagcgtt tttgtgttcc actctaacca ttatagcatt cttctcagct agtgtactaa
      241 ggagtgtgtg cctgaaaata tgggaactaa ggggctggtt tatcggtttc tctagtttag
      301 tatttgcctt ttgcaaagtg atgttaaatg cctttctcta aattcacata tcactattgt
      361 ttaacaaaat ctaatctact ttaggtcact tattcttttt ttgaaatgta gaatgaactt
      421 tttcaaagtt tttcgaatct tttaaaatct gtttgtttta tatcgccatt ctcccccttt
      481 tttaattctc cctatatagc ctgatagctt tcccgatggt acgaatatgg ttgctttcgt
      541 ctaggtggat gtcggggtat tcgggattga gtttttttga ggcagccttg gcggagtttc
      601 ttgacatagt tagtgccgtc tacttggaag atgccgatgg tattatagtc aatctgtggg
      661 gtattcttga taaataggta gtcgctgttt cttatctttg gctccatgga cttgctgacg
      721 acataagcga ttgggtcgta gtcgtctggg ataatggaaa ctccataact aaatcgtcgt
      781 cctgcatcga gcggctacct gcagagataa actacctaac acgagagtaa gtagtctgtc
      841 tgtagtcgtc cagtctgatg atttttacga tacttcgttt ttctgatcat acagttgcct
      901 ctcggcatag gtcagaactt taccttgtct gggtggtgcc cgttggtcgt agatagattg
      961 gatatcgcta ggagaatcct tttgaactgg aggaaagagg gcatcaatca agctactgaa
     1021 tactttaact aagtcaaata tagtattttt cttagtagac ctaacccttt tttcataatt
     1081 tctaatggtg tttttactta tacctatctt agtacccaat tcttattgag tccaaccatt
     1141 actagtctat attgttttat agttgattga gtttggaata gtacgctgta gctgctaaaa
     1201 catttctagg aattaatttg cctttcctaa tagagttgtt catatcttat ttcaatctat
     1261 tatatttttc gcctctaaca atcgcaatct cttctttatc tacgaacgaa atcgctttct
     1321 atttttgtaa gtaaagcatc acacgaaatc cacgaaaatg aaaacctttg ttgtgttttc
     1381 gtaaaaaatt tgttgacaga gcacgaaacg cctactataa ttaaatcaag tttaaggaaa
     1441 taacaaaaaa acaaatcgga gggaaagacg atgaacacat taaatgagaa agtaatcaat
     1501 atctgtaaag cagtagttaa agaaacttta atccaagaca tttaggagaa agaaatgaag
     1561 aaatcaagaa aattagccac attaggaatc tgttcagcct tgtttttagg cttggctgct
     1621 tgtcaacaac aacatgctac ttctgagggt acgaatcaaa ggcaaagcag ttcagcgaaa
     1681 gttccatgga aagcttcata caccaaccta aacaaccagg taagtacaga agaggtcaaa
     1741 tctctcttat cagctcactt ggatccaaat agtgttgatg cattttttaa tctcgttaat
     1801 gactataata ccattgtcgg ctcaactggc ttatcaggag atttcacttc ctttactcac
     1861 accgaatacg atgttgagaa aatcagtcat ctctggaatc aaaagaaggg cgatttcgtt
     1921 gggaccaact gccgtatcaa tagttattgt cttttgaaaa attcagtcac cattccaaag
     1981 cttgaaaaga atgaccagtt gcttttccta gataatgatg cgattgataa aggaaaggtc
     2041 tttgattcac aagataagga agagtttgat attctatttt cgagagttcc aactgaggca
     2101 actacagatg tcaaggttca cgctgaaaag atggaaacat tcttctcaca atttcaattc
     2161 aatgaaaaag ctcgaatgct gtctgtagtc ttgcacgaca atctggatgg cgagtatctg
     2221 tttgtaggcc acgttggggt cttagtacct gctgatgacg gtttcttatt tgtagagaaa
     2281 ttgactttcg aagagcccta ccaagcgatt aaatttgcta gtaaggaaga ttgctacaag
     2341 tatttgggca ccaagtatgc ggattataca ggcgagggac tggctaagcc ttttatcatg
     2401 gataatgata agtgggttaa actttaatag tgttatgata tgacagtaat cttaggattt
     2461 ttatttctat ttttgataag ttggtgggtt atttcaatcg ttaatagcca gaaaccacgc
     2521 aaaaatgaaa catttattgg ctatgtccaa agatacgata ttgatgggaa tggctatcaa
     2581 tcattaccgt gtcctcagaa ctgagaggag ttcttgaaat cgtaacacca ctttgaacaa
     2641 gagttacttc aacccattgg ctccgacgga gtaagttgct ttcgtggata ccaaaaacag
     2701 ccgcaatttg ttcataagtg cgatattctc gcacttattg aagagtggcc ataagaaggt
     2761 cttctaggct taatttaggt tttcgtccac cttttgcgtg tttaagttga taagctgttt
     2821 ttaatacagc taacatctct ttaaaagtcg tgcgttgaac accaacaaga cgcttaaatc
     2881 gtgcatcggt tagttgttta cttgcttcat aattcataga actattatac catattttgt
     2941 ttcgcaggaa gtctaatgct aaaatcttat cagtgagaag atttcttaaa gtttattctt
     3001 tgtagtttca tctgtattag tacataattt aacttagaga aaataggagg actaatcgaa
     3061 tggaattaaa agattttaca gaaaaagaac aggaaatgat taagaaaagg cttacaatgt
     3121 ctaatattag tgacaaagaa actactgaga agattctggc gctagtccca caagacttga
     3181 ttaagcgaat cccgtttttt gtcagaaaac atgctacaac acgtacgatt aaacgcattt
     3241 caattgaata ccctgaactc tacgctgtag ctcaaacaag tggtgagatt ccagaaaaaa
     3301 aaacgcgaag aattgcgtca gattatcaca actatctttg aacaaaagat gaataagcat
     3361 agtattaagt agagaatgaa aaaatatttt attggcggtt tgggaagcaa tgcctatcat
     3421 agcaaggatt ttcttcaaga actagattcg caggtctatt ttctaaatcc atatgaaaag
     3481 catcttcgag atgaaacaga attgaaatca tggtttaaaa atgagattgt agaggaagaa
     3541 tctatctgtc tgataggtca ttctattgga ggcgatttag ctcgttattt cgcatcggaa
     3601 tttgaagaag taaagaaact gattcttttg gatggtggct atctagattt agataagatt
     3661 ttacctttgg atacagagtt agaggaaact aaaaattata tcaaatctca aattatttcg
     3721 gacttagatg ttcttacttc taaagaaaaa tctgaagcaa agcattggtc agaaaatatg
     3781 gagaaagctg taagacagtc ctatcactgg aatgttgagt ataatagata tgagttggct
     3841 ataaattatg aaaatataga agcgatactc cgcctacgga gaaaaataca agcttttaag
     3901 agagaagtgg gagatacctt gtttattagt cctcgctatc ctaatgaagc tacatggaga
     3961 gaggaagccc taaaagaatt gccagactat tttgatacta tttttttaga aaactttggc
     4021 catgagcttt atactcaagc acctaaagaa atcgctagtc taatgaatga gtggctcgct
     4081 tattttctat gagctacttg tattgctgga aatggtataa gatgaaaatc tacaagtcac
     4141 taattttcat ataaccaaaa aacgaacagg ctctttttct gttattcaga agagaacttg
     4201 ttcgttttta tcttgatttt cttaaaaagc tctatataca tagggatttt ctggtttatc
     4261 gactttggta aagctgtcga tttccaaggt tggaaggttt tgtttgagtt ctttatggta
     4321 gtgattgacc agttttcctt tggctgaaat ccaagtgttg ttttcatact gccgggtatt
     4381 gcccttggtc agcaatccat agacaccaga atctgcgatg cagtgaataa tgccgaagcg
     4441 gaacagaaat tggctattgg catgactggg gtcattatag acaaagcctg tgaactggat
     4501 tgtcttaccc tcaaattcat ctggatagtc gtagatagcc tccatgacct ccatatagtt
     4561 ttcattagtg atctgaatac tatcttggga taagtattta tccgccgccg ttcgcatttc
     4621 cttttcatag gctgattttg aaaaataaga actggtatct ggtttcaaat attggcttgt
     4681 cgtcccttcg cttgtctgaa tggctagatc cgttccttcc gataggggga aatgataacc
     4741 tttagcagaa acggtctgag aatccaagct aacagttggg aaagttaagc cgatgacaag
     4801 tggaatagcc agaagagaaa tactcgtcat cttggctaat cggctgttca gatgactgtg
     4861 ggttttgact tgcttcatcc agatatacaa ttgaacgata gccaagataa aagaaagcac
     4921 catggagata taggccagat aggaatagtg catgttgatg tactggttta gtttgcccga
     4981 cagatggagg taaatagtca gttcaaaata gccagctaaa actaaaaatc gaatcatagg
     5041 atgactccaa tcaagagaga atagactaag acgacaagag ttacaattgt tatgaagtga
     5101 ctgataaatc gtgctttcaa gtaatttttc atcatgagaa tatttttgat atccagcatt
     5161 ggaccaatga cgagaaaggc cagaactggt gccaaaccga aactcgagag aagagaagca
     5221 cctataaagg catccgcctc actacagagc gaaagaagaa aggctaaaat catcaagagc
     5281 aggatggcaa aaagaggggt cgcactgata gaggtcagaa tccgagtcgg aacgtagacc
     5341 tgtattatag aagcaaagag gcagccaaat accaaataac gccccgtatc aaaaaattca
     5401 tcaatggcct gcacaaagac ttgaaaaact ttttttgcag aactcaagta agaaaaatca
     5461 tgctcatgac aagccagacg attttctttc tgaatcggtt cttgccagaa aaatcctaga
     5521 aaaattccta gtattacagc cacaagaatg gaacccagag ctcgtaatag ggcgacatgg
     5581 aaggagttgc caaaggcaga ataggtcgca aaaagaacaa tgggattgat aacaggtgct
     5641 gtcacaagaa aaggaacggc cgtgtaactt ggaacctttt tttccagaaa acgattgatg
     5701 atggggacga ttccacattc acaagaaggg aaaaacatac cgacgaaggt cccaaaaaag
     5761 attctccccc aacgatttcg agggagaaaa tgataaacct tgtcaggtgt gatataaact
     5821 tcaatcagcc ctgagacaat gcttcctatc agaacgaagg gaagggcttc aatgataatg
     5881 gagagaaaaa tggctccagt ttgaagtaca ctagatggga gttgttgaaa agcagtcatc
     5941 tagtttttct tttctgcttt ggcttttttc tctttgtcat cagggaaagt aacttgtttc
     6001 aaatcaggga gtttagcaaa ctcttcaaac atcttgtcca agtcgtctcg ttttgtaaat
     6061 tttacagcca taggtgtacc tcgattctaa attctacctc tattatacta ttattttgcg
     6121 gaaaagggag ttttttaatt tgttttcgat agttgatact cttcgaaaat ctcttcaaac
     6181 cacgtcagct tcgccttacc gtagta
//
LOCUS       DAVBOG010000082         5903 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.083, whole genome shotgun sequence.
ACCESSION   DAVBOG010000082 DAVBOG010000000
VERSION     DAVBOG010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5903
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.083"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            61..1887
                     /gene="glpO"
                     /locus_tag="VQ865_002040"
     CDS             61..1887
                     /gene="glpO"
                     /locus_tag="VQ865_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001865074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HET3136324.1"
                     /translation="MEFSKKTRELSIKKMQERTLDLLIIGGGITGAGVALQAAASGLE
                     TGLIEMQDFAEGTSSRSTKLVHGGLRYLKQFDVEVVSDTVSERAVVQQIAPHIPKPDP
                     MLLPVYDEDGATFSLFRLKVAMDLYDLLAGVSNTPTANKVLSKDQVLERQPNLKKEGL
                     VGGGVYLDFRNNDARLVIENIKRANQDGALIANHVKAEGFLFDESGKITGVVARDLLT
                     DQVFEIKARLVINTTGPWSDKVRNLSNKGTQFSQMRPTKGVHLVVDSSKIKVSQPVYF
                     DTGLGDGRMVFVLPRENKTYFGTTDTDYTGDLEHPKVTQEDVDYLLGIVNNRFPESNI
                     TIDDIESSWAGLRPLIAGNSASDYNGGNNGTISDESFDNLIATVESYLSKEKTREDVE
                     SAVSKLESSTSEKYLDPSAVSRGSSLDRDDNGLLTLAGGKITDYRKMAEGAMERVVDI
                     LKAEFDRSFKLINSKTYPVSGGELNPANVDSEIEAFAQLGVSRGLDSKEAHYLANLYG
                     SNAPKVFALAHSLEQAPGLSLADTLSLHYAMRNELTLSPVDFLLRRTNHMLFMRDSLD
                     SIVEPVLDEMGRFYDWTEEEKATYRADVEAALANNDLAELKN"
     gene            1957..2661
                     /locus_tag="VQ865_002041"
     CDS             1957..2661
                     /locus_tag="VQ865_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HET3136325.1"
                     /translation="MMNELFGEFLGTLILILLGNGVVAGVVLPKTKSNSSGWIVITMG
                     WGIAVAVAVFVSGKLSPAHLNPAVTIGVALKGGLPWASVLPYILAQFAGAMLGQILVW
                     LQFKPHYEAEENAGNILATFSTGPAIKDTVSNLISEILGTFVLVLTIFALGLYDFQAG
                     IGTFAVGTLIVGIGLSLGGTTGYALNPARDLGPRIMHSILPIPNKGDGDWSYAWIPVV
                     GPVIGAALAVLVFSLF"
     gene            2958..3161
                     /locus_tag="VQ865_002042"
     CDS             2958..3161
                     /locus_tag="VQ865_002042"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136326.1"
                     /translation="MPKWSNPDYVNELDPKIVDMLVEFHKSQGTLETPEAQAEIAQKR
                     EEIEQRRAELEDKKQELLNRLNK"
     gene            complement(3248..3508)
                     /locus_tag="VQ865_002043"
     CDS             complement(3248..3508)
                     /locus_tag="VQ865_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001843823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136327.1"
                     /translation="MTGAGISYMIGRIGALLGGPWGAIIGGAYFGIQAYQSYLDSQSP
                     YPYYITSTYIHVAQRKWKFITEYYRNSNYTGYVKTVTTYVNF"
     gene            complement(3563..3907)
                     /locus_tag="VQ865_002044"
     CDS             complement(3563..3907)
                     /locus_tag="VQ865_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000041363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136328.1"
                     /translation="MSKMFKCMCLLVMSVFCMSSISPSLVVFADDSLSANSKVVSGEA
                     QFENGSSVRFGDTQVNILSDEVLEVVNPDGSVDTIERRADGVYINGAFYMAYQKNEID
                     LNISFRSYDPNV"
     gene            4945..>5903
                     /gene="ltrA"
                     /locus_tag="VQ865_002045"
     CDS             4945..>5903
                     /gene="ltrA"
                     /locus_tag="VQ865_002045"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000040325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HET3136329.1"
                     /translation="MSKLLDKILSRENMLEAYNQVKSNKGSAGIDGMTIEEMDNYLRQ
                     NWRLTKELIKQRKYKPQPVLKVEIPKPDGGIRQLGIPTVMDRMIQQAIVQVMSPICEP
                     HFSDTSYGFRPNRSCEKAIMKLLEYLNDGYEWIVDIDLEKFFDTVPQDRLMSLVHNII
                     EDGDTESLIRKYLHSGVIINGQRYKTLVGTPQGGNLSPLLSNIMLNELDKELEKRGLR
                     FVRYADDCVITVGSEAASKRVMYSVSRFIEKRLGLKVNMTKTKITRPRELKYLGFGFW
                     KSSDGWKSRPHQDSVRRFKFKLKKLTQRKWSIDLTRRIEQLNLS"
BASE COUNT         1837 a         1141 c         1295 g         1630 t
ORIGIN      
        1 agattttcga agagtataat actggcagaa taaagcgatt tatttagaaa gtgtgtaaat
       61 atggaatttt caaagaaaac acgtgaattg tcaattaaaa aaatgcagga acgcaccctg
      121 gacctcttga ttatcggtgg aggaatcaca ggagctggtg tagccttgca ggcggcagct
      181 agcggtcttg agactggttt gattgaaatg caagactttg cagaaggaac atctagtcgt
      241 tcaacaaaat tggttcacgg aggtcttcgc tacctcaaac aattcgacgt agaggtggtc
      301 tcagatacgg tttctgaacg tgcagtggtt caacaaatcg ctccacacat tccaaaacca
      361 gatccaatgc tcttaccagt ttacgatgaa gatggagcaa cctttagcct cttccgtctt
      421 aaagtagcca tggacttgta cgacctttta gcaggtgtga gcaacacacc aactgcgaac
      481 aaggttttga gcaaggatca agtcttggaa cgccagccaa acttgaagaa ggaaggcttg
      541 gtaggaggtg gagtgtatct tgacttccgt aacaacgatg cgcgtctcgt gattgaaaac
      601 atcaaacgtg ccaaccaaga cggtgccctc attgccaacc acgtgaaggc agaaggcttc
      661 ctctttgacg aaagtggcaa gattacaggt gttgtagctc gtgatctctt gacagaccaa
      721 gtatttgaaa tcaaggcccg tctggttatt aatacaacag gtccttggag tgataaagta
      781 cgtaatttgt ctaataaggg aacgcaattc tcacaaatgc gcccaactaa gggagttcac
      841 ttggtagtgg attcaagcaa aatcaaggtt tcacagccag tttactttga cacaggtttg
      901 ggtgacggtc gtatggtctt tgttctccca cgtgaaaaca agacttactt tggtacaact
      961 gatacagact acacaggtga tttggagcat ccaaaagtaa ctcaagaaga tgtagattat
     1021 ctacttggca ttgtcaacaa ccgctttcca gaatccaaca tcaccattga tgatatcgaa
     1081 agcagctggg caggtcttcg tccattgatt gcagggaaca gtgcctctga ctataatggt
     1141 ggaaataacg gtaccatcag tgatgaaagc tttgacaact tgattgcgac tgttgaatct
     1201 tatctctcca aagaaaaaac acgtgaagat gttgagtctg ctgtcagcaa gcttgaaagt
     1261 agcacatctg agaaatattt ggatccatct gcagtttctc gtgggtctag cttggaccgt
     1321 gatgacaatg gtctcttgac tcttgctggt ggtaaaatca cagactaccg taagatggct
     1381 gaaggagcta tggagcgcgt ggttgacatc ctcaaagcag aatttgaccg tagctttaaa
     1441 ttgatcaatt ctaaaactta ccctgtttca ggtggagaat tgaacccagc aaatgtggat
     1501 tcagaaatcg aagcctttgc gcaacttgga gtttcacgtg gtttggatag caaggaagct
     1561 cattacctag caaatcttta cggttcaaat gcaccgaagg tctttgcact tgctcacagc
     1621 ttggaacaag cgccaggtct tagtttggca gacaccttgt cccttcacta tgcaatgcgc
     1681 aatgagttga ctcttagccc agttgacttc cttcttcgtc gtaccaatca catgctcttt
     1741 atgcgtgata gcttggatag tatcgttgag ccagttttgg atgaaatggg acgattctat
     1801 gactggacag aagaagaaaa agcaacttac cgtgctgatg tcgaagcagc tctcgctaac
     1861 aacgatttag cagaattaaa aaattaagaa aaaataaaag aggtggaggg cagcattcct
     1921 tgtcgcccgt cccttctttt taatggagac agaaagatga tgaatgaatt atttggagaa
     1981 tttctaggga ctttaattct gattcttcta ggaaatggtg ttgttgcagg tgtggttctt
     2041 cctaaaacca agagcaatag ctcaggttgg attgtgatta ctatgggttg ggggattgca
     2101 gttgcggttg cagtctttgt atctggcaag ctcagtccag ctcatttaaa cccagctgtg
     2161 accatcggtg tggccttaaa aggtggtttg ccttgggctt ccgttttgcc ttatatctta
     2221 gcccagttcg caggggccat gctgggtcag attttggttt ggttgcaatt caaacctcac
     2281 tatgaggcag aagaaaatgc aggcaatatc ctggcaacct tcagtactgg accagccatc
     2341 aaggatactg tatcaaactt gattagcgaa atccttggaa cctttgtttt ggtgttgaca
     2401 atctttgctt tgggtcttta cgattttcag gcaggtatcg gaacctttgc agtgggaact
     2461 ttgattgtcg gtatcggtct atcactaggt gggacaacag gttatgcctt gaacccagct
     2521 cgtgaccttg gacctcgtat catgcacagc atcttgccaa ttccaaacaa gggagacgga
     2581 gactggtctt acgcttggat tcctgttgta ggccctgtta tcggagcagc cttggcagtg
     2641 cttgtattct cacttttcta gtttatactc ttcgaaaatc aaattcaaac cacgtcagcg
     2701 tcgccttacc gtactcaagt acagcttgcg gctagcttcc tagtttgctc tttgattttc
     2761 attgagtatt agaaaacaat tatgttgata gagcttgggc aagagcccaa tttcagcaaa
     2821 aaatgaagta aatcttctca taataaaacg catcatatca agcacgaaaa ttccacgagg
     2881 tcaactacag tcagaaagct gaacaacaag ccaaaacgcc caaaaaaggc ggcaaaaagc
     2941 aagcacctgc aagcaacgtg ccgaaatggt caaatcctga ttatgtcaac gaattagacc
     3001 caaaaatcgt tgatatgcta gtagaatttc acaagtcaca aggcactttg gaaactcccg
     3061 aggcgcaagc agaaatcgcc caaaaacgtg aagaaatcga gcaaaggaga gctgagcttg
     3121 aggataaaaa acaagagctt ttgaaccgct tgaacaaata gagtttcgca agtattatgc
     3181 ttacaaatta cttgagcaat taactaaaat ataaaccctg cctttatatc taggcagggt
     3241 ttatatttta gaaattcacg taggttgtta cggtttttac atacccagta tagtttgagt
     3301 ttctatagta ttcagtgata aacttccatt ttctttgagc aacatggata taagtacttg
     3361 ttatgtagta tggatatggg ctttgtgaat ccaagtaaga ctgataagct tgtataccaa
     3421 aatatgctcc accaattatt gcaccccatg gaccccccaa taaagcacct atcctaccaa
     3481 tcatataact gattccagca ccagtcatga agttagcgaa tgtgttagct tgtttattcc
     3541 catgtattgt gttgacgtaa tttcaaacat taggatcgta tgatctaaaa gatatattta
     3601 ggtcgatttc attcttttga taagccatat aaaatgcccc attgatatag acgccgtcag
     3661 cacgtcgttc aatagtgtct acacttccat ctggattgac aacctcaaga acttcatcgc
     3721 ttaaaatatt tacttgcgta tctccgaacc gcactgatga gccattctca aactgagcct
     3781 caccagatac aactttagag tttgccgata agctatcatc agcaaaaaca acaagcgacg
     3841 gggaaatgct agacatacag aaaacagaca taactagcaa acacatgcat ttaaacatct
     3901 tagacataac ggaaactctt ttgtattttt gatttttttc aacttttatt atacaataaa
     3961 accaaataaa aagaaagcgg taacaatatg cttaatgcga aaatttttta tatattttta
     4021 tgtttgatcg ttatcgaaac tacaggcttg ttgttgttga aaagaggtct cgaaatgggt
     4081 tatttagaca cagaagctat tatcctcgca gttttttcat ttgcttttta caacctatgt
     4141 tcattcgctt gggtctgctc tacaataaaa aacaataaaa aataaataga cgtattttca
     4201 aaaaaaaaaa aatgcatatt tatcttagca aaatgacgat ttaaatcgtc gtttttttgt
     4261 agtacgacgg gcatgtcgta tatctgaggt gtaagtcctc ggtgggcacc tgctaccggt
     4321 gaacccaata gcgattccca agcctgacta tcgtgaggta gcagggagag gaagggatag
     4381 cgaaatcgtg gctctacgaa caggaacgtg atagtaaggc gtatatagcg gataaggagg
     4441 cttcaaactc taaagtccaa aaaggtagtc gtaacctata tgtgtaaatc acgagagtaa
     4501 ttgaattcgg actaaggttt gtgtgaaaaa gataaatctt tctagagtct aaagactctg
     4561 cgtcagattt cctattttca ctgtaacctt ttaacgtcct catatcttgt ataaacgagg
     4621 aaagatgtac gacttatccc gtgaggtttc atgagcgctg aaagcgtagt aacaacgaat
     4681 catgagaagt cagccgagcc catagtagtg aggaaacttc tgtagtggaa gtggagcgac
     4741 ggggtgaata ctcaaacagt ctggggagag actgtttgag gtctgtcgct agaaagagaa
     4801 aacgacagat cgaagtaatc ctacttcact tgtgtctgta aaatgagtgg tctgatagaa
     4861 ctggactttg acacgtaatg actagatgaa ggttcaccaa tataagatgt ccctcaggca
     4921 ccaaaacaag aaaggaatag gcacatgtca aaactgctag ataagatatt atcacgcgaa
     4981 aatatgctgg aagcctacaa tcaagtaaaa tccaataaag gctcagctgg gattgatgga
     5041 atgactatcg aagagatgga taattatctc agacaaaact ggcgcttgac taaggaactg
     5101 ataaaacaga gaaaatataa gcctcaacca gttcttaaag ttgagatacc taaaccagac
     5161 ggaggcatcc gtcaactagg aattccaaca gttatggata gaatgattca acaggccatt
     5221 gtccaagtca tgagccccat ttgtgaaccc catttctcag atacgagtta tggtttcaga
     5281 ccaaataggt catgtgaaaa agccatcatg aagctcttag aatacttaaa tgacggctat
     5341 gagtggatag tggatataga cctagagaaa tttttcgata cagttcctca agatagattg
     5401 atgtccttag tacataacat tatcgaagac ggagatacgg aatccttgat tcgtaagtat
     5461 cttcattcag gtgttatcat taatggtcaa cgttataaaa cactagttgg tacaccacag
     5521 ggaggaaatt tatctcctct cttatccaat atcatgctta atgaattgga caaggaatta
     5581 gaaaagaggg gacttcgatt tgtgcgctac gcagatgatt gtgtgattac ggtcggaagc
     5641 gaggcagcct ctaagcgtgt gatgtattca gtcagtcgtt ttattgagaa acggctaggt
     5701 ttgaaagtaa acatgaccaa gactaagatt accagaccaa gagagttgaa atatctaggt
     5761 tttgggttct ggaaatcatc agatggttgg aaaagccgtc cacatcaaga tagtgttcgg
     5821 agatttaagt ttaaattgaa gaaactaaca cagaggaaat ggagtataga cctaacaaga
     5881 cgtattgagc aactgaattt gtc
//
LOCUS       DAVBOG010000083         5511 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.084, whole genome shotgun sequence.
ACCESSION   DAVBOG010000083 DAVBOG010000000
VERSION     DAVBOG010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5511
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.084"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            80..718
                     /locus_tag="VQ865_002046"
     CDS             80..718
                     /locus_tag="VQ865_002046"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004261378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HET3136330.1"
                     /translation="MSKGFLVSLEGPEGAGKTSVLEALLPILEEKGVKVLTTREPGGV
                     LIGEKIREVILDPSHTQMDAKTELLLYIASRRQHLVEKVLPALEAGKLVIMDRFIDSS
                     VAYQGFGRGLDIEAIDWLNQFATDGLKPDLTLYFDIEVEEGLARIAANSDREVNRLDL
                     EGLDLHKKVRQGYLSLLDKEGNRIVKIDASLPLEQVVETTKAVLFDGMGLAK"
     gene            715..1605
                     /locus_tag="VQ865_002047"
     CDS             715..1605
                     /locus_tag="VQ865_002047"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HET3136331.1"
                     /translation="MKQDQLKAWQPAQFDRFVRILEQDQLNHAYLFSGFFGSLEIAQF
                     LAKSLFCTDKVGVLPCEKCRSCKLIEQGEFPDVTLIKPVNQVIKTERIRELVGQFSQA
                     GIESQQQVFIIEQADKMHPNAANSLLKVIEEPQSEVYIFFLTSDEEKMLPTIRSRTQI
                     FHFKKQEEKLILLLEQMGLVKKKATLLAKFSQSRAEAEKLANQASFWTLVDESERLLT
                     WLVAKKKESYLQVAKLANLADDKEKQDQVLRILEVLCGQDLLQVRVRVILQDLLEARK
                     MWQANVSFQNAMEYLVLKEI"
     gene            1645..1962
                     /gene="yabA"
                     /locus_tag="VQ865_002048"
     CDS             1645..1962
                     /gene="yabA"
                     /locus_tag="VQ865_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000358230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HET3136332.1"
                     /translation="MDKKELFDALDDFSQQLLVTLADVEAIKKNLKSLVEENTALRLE
                     NSKLRERLGEVEADAPVKAKHVRESVRRIYRDGFHVCNDFYGQRREQDEECMFCDELL
                     YRE"
     gene            1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ865_002049"
     CDS             1965..2834
                     /gene="rsmI"
                     /locus_tag="VQ865_002049"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001166894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HET3136333.1"
                     /translation="MQIQKSFKGQSPYGKLYLVATPIGNLDDMTFRAIQTLKEVDWIA
                     AEDTRNTGLLLKHFDISTKQISFHEHNAKEKIPDLIGFLKAGQSIAQVSDAGLPSISD
                     PGHDLVKAAIEEEIAVVTVPGASAGISALIASGLAPQPHIFYGFLPRKSGQQKQFFDS
                     KKDYPETQIFYESSHRVADTLENMLEVYGDRSVVLVRELTKIYEEYQRGTISELLESI
                     AETPLKGECLLIVEGASQDVEEKDEEDLFLEIQARIQQGMKKNQAIKEVAKIYQWNKS
                     QLYAAYHDWEEKQ"
     gene            3061..3579
                     /locus_tag="VQ865_002050"
     CDS             3061..3579
                     /locus_tag="VQ865_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HET3136334.1"
                     /translation="MRTYENKEELKAEIEKTFEKYILEFDNIPENLKDKRADEVDRTP
                     AENLAYQVGWTNLVLKWEEDERKGLQVKTPSDKFKWNQLGELYQWFTDTYAHLSLQEL
                     KAKLNENINSISAMIDSLSEEELFEPHMRKWADEATKTATWEVYKFIHVNTVAPFGTF
                     RTKIRKWKKIVL"
     gene            3688..4335
                     /locus_tag="VQ865_002051"
     CDS             3688..4335
                     /locus_tag="VQ865_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000345255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HET3136335.1"
                     /translation="MDFEYFYNREAERFNFLKVPEILVDREEFRGLSAEAIILYSILL
                     KQTGMSFKNNWIDKEGRVFIYFTVEEIMKRRNISKPTAIKTLDELDVKKGIGLIERVR
                     LGLGKPNIIYVKDFMSIFQVKENDLQKSKNLTSEVKDFNLRSKENELQEVKNLDSNYI
                     ENNKSKYSKREYSFGENGLGTFQNVFLAAEDISDLQIIMNSQLENYIRLPAKLES"
     gene            complement(4324..5129)
                     /locus_tag="VQ865_002052"
                     /pseudo
     CDS             complement(4324..5129)
                     /locus_tag="VQ865_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS5 family transposase"
     gene            5124..5378
                     /locus_tag="VQ865_002053"
     CDS             5124..5378
                     /locus_tag="VQ865_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001244258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HET3136336.1"
                     /translation="MHRTTIPYFVSQEVYWKVRNIGAEAIRRNCERGAIFSGKIKHHE
                     DSQFKGEHYVECYAVLDNTVIARDRITVPIDPLCGKDFIE"
BASE COUNT         1796 a          912 c         1214 g         1589 t
ORIGIN      
        1 aaatgagaag acaaaaagat tgtcacaaac ccctattttt ttgatagaat agaagtagta
       61 aaaaagaaat gagttagaca tgtcaaaagg atttttagtc tctcttgagg gaccagaggg
      121 agcaggcaag accagtgttt tagaggctct gctaccaatt ttagaggaaa aaggagtaaa
      181 ggtgctgacg acccgtgaac ctggcggagt cttgattggg gagaagattc gggaagtgat
      241 tttggatcca agtcatactc agatggatgc taaaacagag ctacttctct atattgccag
      301 tcgcagacag catttggtgg aaaaagttct tccagccctt gaagctggca agttggtcat
      361 catggatcgt tttatcgata gttctgttgc ctatcaggga tttggtcgtg gcttagatat
      421 tgaagccatt gactggctca atcagtttgc gacagatggc ctcaaacccg atttgacact
      481 ctattttgac atcgaggtgg aagaagggct ggctcgtatt gctgctaata gtgaccgcga
      541 ggttaatcgt ttggatttgg aagggttgga cttgcataaa aaagttcgtc aaggctacct
      601 ttctcttctg gataaagagg gaaatcgcat tgtcaagatt gatgctagtc tccctttgga
      661 gcaagttgtg gaaactacca aggctgtctt gtttgacgga atgggcttgg ccaaatgaaa
      721 caagatcaac taaaggcttg gcaaccagct cagtttgacc gttttgtccg tatcttagaa
      781 caagaccagc tcaatcacgc ctatctcttt tcaggtttct ttggaagctt ggaaatagcg
      841 caatttttag ctaagagcct cttttgtacg gataaagttg gcgtcttacc atgtgagaaa
      901 tgccgaagtt gcaagctgat tgaacaggga gaatttcccg atgtcacctt gattaagcca
      961 gtcaatcagg tcatcaagac agaacgcatt agggaattgg tgggacagtt ttctcaagca
     1021 gggattgaaa gccagcaaca ggtctttatc atcgagcaag cggataaaat gcatcccaac
     1081 gcagccaatt ctctgctcaa ggtcatcgaa gaaccccaga gtgaagttta tattttcttc
     1141 ttgactagcg atgaggaaaa gatgttaccg acaatccgaa gtcggaccca gatcttccac
     1201 tttaaaaagc aagaagaaaa acttatctta ctcttagaac aaatgggact tgttaagaaa
     1261 aaagcgactc ttttagctaa gtttagtcaa tcgcgagctg aagcagaaaa gttggctaat
     1321 caggcaagtt tttggacctt ggtcgatgaa agtgaacgcc tgctgacttg gttagtagct
     1381 aagaaaaaag aaagttatct acaggttgcc aaattagcca acttggcaga tgataaggaa
     1441 aaacaggatc aggttttacg gattcttgaa gttctctgtg ggcaggacct cttgcaggta
     1501 agagtaagag tgattctaca agatttacta gaagctagaa aaatgtggca agctaatgtc
     1561 agctttcaaa atgccatgga atatctggtc ttgaaagaaa tataaactca aaaatgaatg
     1621 ataaagaaag gaaagagctg ttttatggac aaaaaagaat tatttgacgc gctggatgat
     1681 ttttcccaac aattattggt aaccttggcc gatgtggaag ccatcaagaa aaatctcaag
     1741 agcctggtag aggaaaatac agctcttcgc ttggaaaata gtaagttgcg agaacgcttg
     1801 ggtgaggtgg aagcagacgc tcccgtcaag gccaagcatg ttcgcgaaag tgtccgtcgt
     1861 atttaccgtg atggatttca cgtatgtaat gatttttatg gacaacgtcg agagcaggac
     1921 gaagaatgta tgttctgtga tgagttgtta tacagggagt aggcatgcaa attcaaaaaa
     1981 gttttaaggg gcagtctccc tatggcaagc tgtatctagt ggcaacgccg attggcaatc
     2041 tagatgatat gacttttcgc gctatccaga ccttgaaaga agtggactgg attgctgctg
     2101 aggatacgcg caatacaggt cttttgctca agcattttga catttccacc aagcagatca
     2161 gttttcatga gcacaatgcc aaggaaaaaa ttcctgattt gattggtttc ttgaaagcag
     2221 ggcaaagtat tgctcaggtc tctgatgccg gtttgcctag catttcagac cctggtcatg
     2281 atttggttaa ggcagctatt gaggaagaaa ttgcagttgt gactgttcca ggtgcctctg
     2341 caggaatttc tgccttgatt gccagtggtt tagcgccgca gccacatatc ttttacggct
     2401 ttttaccgag aaaatcaggt cagcaaaagc aatttttcga ctcgaaaaaa gactatcctg
     2461 aaactcagat tttttatgaa tcgtcccatc gtgtggcaga tacattggaa aatatgctag
     2521 aagtctacgg tgaccgctcg gtagtcttgg tcagggaatt gactaaaatc tatgaagaat
     2581 accaaagagg taccatttct gaattgctgg aaagcatcgc tgaaacgcca ctcaagggcg
     2641 aatgccttct tattgttgaa ggtgccagtc aggatgtgga ggaaaaagac gaggaggact
     2701 tgttcttaga aatccaagcc cgtatccagc aaggcatgaa gaaaaatcaa gctattaagg
     2761 aagtagctaa gatttaccag tggaataaga gtcaactcta cgctgcctac cacgattggg
     2821 aagaaaaaca ataaagggag acagaatgta ataattctgt ctgtttctgt ttaacttaat
     2881 tagtgatggt aatataaaga tgtatcactt ggtatagaag ctttggtatt aagtttttta
     2941 ttaagcccat acggaatacc gatggttgga gcagcagtta tagcgttctt agaaggtata
     3001 aatagaaaaa taaggtcatt ttaaatcaaa ggattgataa atcagaaaga aggtgatttt
     3061 ttgcgaacat acgaaaataa agaagaacta aaagctgaga tagagaaaac atttgagaaa
     3121 tatattttag aatttgataa tattccagaa aatttaaaag ataagagagc tgatgaagtt
     3181 gacagaactc cagcagaaaa ccttgcttat caggttggtt ggaccaactt ggttcttaaa
     3241 tgggaagaag atgaaagaaa ggggcttcaa gtaaaaacac catcggataa atttaaatgg
     3301 aatcaacttg gtgaattata tcagtggttc acagatacct acgctcattt atctctgcaa
     3361 gagttgaaag caaaattaaa tgaaaatatt aattctatct ctgcaatgat tgattcgttg
     3421 agtgaggaag aattatttga accgcatatg agaaagtggg ctgatgaagc gactaaaaca
     3481 gcgacttggg aagtgtataa gtttattcat gtaaatacgg ttgcaccttt tggaactttc
     3541 agaactaaaa tcagaaaatg gaagaagata gtattataaa ttatattttt aactttaaaa
     3601 aatttcataa aaatggttac caaaggcgat agaagaaaaa ctatcgtctt tttctttgca
     3661 aatttttaag aagggaggtg atcttgcatg gactttgaat atttttataa cagagaagcg
     3721 gaaagattta acttcttaaa agtaccggag atattagttg atagagaaga atttcggggc
     3781 ttatcagcag aagcaattat cctttattcc atacttctta aacagacagg aatgtcattt
     3841 aagaataact ggatagacaa ggaaggcaga gtatttatct attttactgt cgaagaaatt
     3901 atgaaaagaa gaaatatctc aaagccaact gccataaaaa cattagatga gcttgatgta
     3961 aaaaaaggaa taggactgat cgaaagagta aggcttggac ttggtaagcc gaacatcatt
     4021 tatgttaaag actttatgag tatatttcag gtaaaagaaa atgacttaca gaagtcaaaa
     4081 aacttaactt cagaagtaaa agattttaac ctcagaagta aagaaaatga acttcaagag
     4141 gttaagaacc ttgactctaa ctatatagag aataataaga gtaagtatag taagagagaa
     4201 tatagttttg gtgaaaacgg acttggaaca tttcaaaatg tgtttttagc tgctgaagat
     4261 atatcggatt tacaaatcat aatgaactca cagcttgaga attacattag acttcctgca
     4321 aaactagaat cctagttcat gattgataat accagcaatc aaattcattc gtaatccgaa
     4381 gcgtttacga tgatttcgat aggttgttga aaacatttta aacgttttta ctttggcaaa
     4441 gatgttctca accttgcttc tctccttaga tagcgcatgg ttacaggctt tatcttcagc
     4501 tgttagcggc ttgagtttgc tggatttacg tggagtttgt gcttgaggat atatcttcat
     4561 gagcccttga taaccactgt cggccaagat tttaccagct tgtccgatat ttctacaact
     4621 cattttgaac aacttcatat catgactata gttcacagcg atatccaaag aaacaattct
     4681 cccttgactt gtgacaatcg cttgagcctt catagcgtga aatttctttt taccagaatg
     4741 attcgctaat tgttttctta gggcgattga tttgtacttc cgtcgcatca atcattaccg
     4801 tgtcctcaga actgagagga gttcttgaaa tcgtaacacc acctttgaac aagagttact
     4861 tcaacccatt ggctccgacg gagtaagttg ctttcgtgga taccaaaatc agccgcaatt
     4921 tattcataag tgcgatattc tcgcacatat tgaagagtgg ccataagaag gttttctagg
     4981 cttaatttag gttttcgtcc accttttgcg tatttaagtt gataagctgt ttttaataca
     5041 gctaatatct cttcaaaagt cgtgcgctga acaccaacaa gacgcttaaa tcgtgcatca
     5101 gttagttgtt tacttgcttc ataattcata gaactactat accatatttt gtttcgcagg
     5161 aagtctattg gaaagtaaga aatattggag ctgaggcgat tagaagaaat tgtgagcgtg
     5221 gtgctatttt ttcaggtaaa ataaaacatc acgaagattc tcagtttaaa ggagagcact
     5281 atgttgaatg ttatgctgtt ttagataata cggttatagc aagagataga ataacagtcc
     5341 ctatcgatcc gttatgtgga aaagatttta tagagtagca tataattgat tcttaactgg
     5401 aatactctct atctctttac atcaagaaaa tgactaaaca gggaagtttg ccttcttccc
     5461 tttttttgtt atactagtag aagaaaaaaa tagaaagatt tgtgggagtg a
//
LOCUS       DAVBOG010000084         5466 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.085, whole genome shotgun sequence.
ACCESSION   DAVBOG010000084 DAVBOG010000000
VERSION     DAVBOG010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5466
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.085"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..1141
                     /locus_tag="VQ865_002054"
                     /pseudo
     CDS             1..1141
                     /locus_tag="VQ865_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000436393.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
     gene            1165..1321
                     /locus_tag="VQ865_002055"
                     /pseudo
     CDS             1165..1321
                     /locus_tag="VQ865_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611222.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1314..1487)
                     /locus_tag="VQ865_002056"
     CDS             complement(1314..1487)
                     /locus_tag="VQ865_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteinase"
                     /protein_id="HET3136337.1"
                     /translation="MNIKKRVLSAGLTFASVLLLAACGQSGSDTKTYSSTFSGNPTTF
                     NYLLDYYTDNIVN"
     gene            complement(1646..3253)
                     /locus_tag="VQ865_002057"
     CDS             complement(1646..3253)
                     /locus_tag="VQ865_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HET3136338.1"
                     /translation="MQEKWWHNAVVYQVYPKSFMDSNGDGIGDLPGITSKLDYLAKLG
                     ITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMEDMDQLIAEAKKRDIRIIMDLVVN
                     HTSDEHAWFVEACENPNSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK
                     KQPDLNWENEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYL
                     KEMNQATFGDKDLLTVGETWGATPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKW
                     HYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSIWGNDQEYREKSAKA
                     FAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDS
                     IRVIGRDNARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKL
                     VQIRKENSWLVRADFELLDTADKVFAYIRKDGDRRFLVVANLSNEEQDLTVEGKVKSV
                     LIENTLAQEVFEKQILVPWDAFCVELL"
     gene            3406..4890
                     /locus_tag="VQ865_002058"
     CDS             3406..4890
                     /locus_tag="VQ865_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008535024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HET3136339.1"
                     /translation="MKKQAFSSEQYLNLQRDHILERINQFDGKLYLEFGGKMLEDFHA
                     ARVLPGYEPDNKIKLLQELKEQVEVVIAINASNIEHSKARGDLGISYDQEVLRLIDKF
                     NELGIFVGSVVITQYAGQPAADAFRNQLEKNGIDSYLHYPIKGYPTDMDHIISPEGMG
                     KNDYIKTSRNLIVVTAPGPGSGKLATCMSNMYHDQINGIKSGYAKFETFPVWNLPLHH
                     PVNLAYEAATADLDDVNMIDPFHLQTYGETTVNYNRDIEIFPVLKRMLERILGKSPYA
                     SPTDMGVNMVGFAITDDEAAVEASKQEIIRRYYQTVLDFKAEKVGEAAVKKIELLMND
                     LGITPADRKVAVVARQKAEETGGPALAFELPNGEIITGKNSELFGPTAAALINAIKKS
                     ADIAKEVKLIEPEVVKPIQGLKIDHLGSRNPRLHSNEILIALAITATENPDAARAMEE
                     LGNLKGSEAHSTIILTDEDKNVLRKLGINVTFDPYYQYDRLYRK"
     gene            4985..>5466
                     /locus_tag="VQ865_002059"
     CDS             4985..>5466
                     /locus_tag="VQ865_002059"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002893508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HET3136340.1"
                     /translation="MSKEVIVESFELDHTIVKAPYVRLIGEETGPKGDIISNYDIRLV
                     QPNEDSIPTAGLHTIEHLLAKLIRTRIDGMIDCSPFGCRTGFHMIMWGRHTSAKIAAV
                     IKDSLKEIAETTTWEDVPGTTIESCGNYKDHSLFSAKEWAKLILEQGISDDAFERHVI
                     "
BASE COUNT         1616 a         1237 c         1002 g         1611 t
ORIGIN      
        1 aaaaaccttc taaaattcct tatcttgaaa caactggtat gcctactaga attctcctta
       61 gaaagcgtcg ctttaagtgc tatcactgtt caaaaatgat ggtcgctgaa acttctatcg
      121 tcaagaaaaa tcaccaaatt cctcgtatta tcaaccaaaa aattgcgcaa aagttaattg
      181 aaaagaattc tatgaccgat attgcccatc agctggccat ctcaacttca actgttattc
      241 gtaagctcaa tgattttcac tttaaacatg atttttcttg tcttcctgag attatgtctt
      301 gggatgagta tgcttttaca aagggaaaga tgagcttcat tgcgcaagat tttaacaagc
      361 tcaatatcat cactgttctt gagggaagaa cacaagctat cattcgaaat cactttcttc
      421 gctacgatag agctgtccga tgtcgcgtca aaattattac tatggatatg tttagccctt
      481 actatgactt agctaaacag cttcgctttc aaatttctag gctcaggctg aaacagtctc
      541 ctagactgtt tcactcccga atgctaaaat cgttcttgat cgctttcata ttgtacaaca
      601 tcttagccgt gctatgagtc gtgtgcgtgt tcaaatcatg aatcagtttc atcgaaaatc
      661 ccatgaatac aaggctatca agcgctactg gaagctcata caacaggata gtcgtaaact
      721 cagcgataaa catttttatc gccctacttt tcgtatgcat ttaaccaata aagagatttt
      781 aaacaagctt ttgagctatt cacaagactt gaaacatcac tatcagctct atcaactctt
      841 gctgtttcac tttcagaata aggaaccgga gaaatttttc ggactcattg aggacaatct
      901 taagcaggtt catcctattt ttcagactgt ctttaaaacc tttctaaagg acaaagagaa
      961 aatagtcaac gcccttcaac taccctattc aaacgccaaa ttggaagcga ccaataatct
     1021 catcaaactt atcaagcgca atgcctttgg ttttcggaac tttgaaaact tcaaaaaacg
     1081 gattttcatc gctctgaaca tcaaaaaaga aaggacgaaa tttgtccttt ctcaagctta
     1141 gcttttcttc aacccactac agttgacaaa gagcctaagc ttttacctct tcctccctac
     1201 tcacctgagt acaatcctat tgagaaaaca tgggctcata tcaaaaagca cctcataaaa
     1261 ggtattacca agttgcaata ccttttatga ggctcttttg tcttgttctt gtttcaattg
     1321 actatattat cagtgtaata gtctaataga tagttaaatg tagttggatt tccactaaag
     1381 gttgatgagt aagtttttgt atctgaacct gattggccgc aagcagctaa aagcaaaaca
     1441 gatgcaaaag tcaggcctgc actaaggaca cgcttcttta tgttcatctt ctttctcctt
     1501 aatagtggga atttgtaaag ttaattgaat ttcgagaatg aaagtttata aaccttggtt
     1561 ataaaaaaca aaggatttct gctttttata cagtcctccc ttgtttttat atgatttcaa
     1621 ttttaaattt ttctgcaaaa aatatttata gtaattccac acagaaagca tcccatggaa
     1681 ctaagatttg tttttcaaag acttcttgag ctagggtgtt ttcaatcaag acagatttga
     1741 cttttccttc tactgtcaag tcttgctctt cattggacaa gttagccaca actaggaagc
     1801 gacggtcgcc atccttacgt atataagcaa agaccttatc agccgtatca agcaattcaa
     1861 agtcagctcg aactagccag ctattctcct tgcgaatttg gaccagtttc tgataggtat
     1921 agaaaataga atctggattt gccagcgctt cttggacatt gatcatctcg taatttggat
     1981 taaccgccaa ccaaggttga cctgttgaga aaccagcgtt tttgctctcg tcccattgca
     2041 taggggtacg ggcattgtca cgtccaataa cacggatact gtccatgatt tcttcaatcg
     2101 gaacaccttt ttcaagagcc tcacgcgcat agttgagaga ttcaatatct tctacttgat
     2161 ccagcgtttc aaagggatag ttggtcatgc caatttcctc accttggtag atataaggag
     2221 ttcctctcat gagatgaagc aagatggcaa aggctttggc agatttttcg cggtattctt
     2281 ggtcatttcc ccagattgag acaatacgag ggaggtcatg gttgttccag aagagggaat
     2341 tccagccgtc ctcaactcct aactctgtct gccatttgtt gaagatttct tttaacttag
     2401 cgatattcag ctctttttga tagtgccatt taggctgacc ttcctgatac tgaagaccga
     2461 tatgttcaaa ctggaagacc atagacaatt cttgcccctt tggatcagag tagagcttgg
     2521 caatctctgg cgttgctccc caagtctccc ctactgtcaa gagatcctta tctccaaagg
     2581 tcgcctgatt catttccttg agatagggat ggagcatagg accattattg actaccttct
     2641 cgtcaggaat tttgccaatc atgtcaataa catccatacg gaaaccacca atacccttat
     2701 caatccagaa gttcatcatc tcataaattt tctggcgaag tttttcattt tcccagttga
     2761 gatccggctg tttcttgctg aaaaagtgga gatagtattg acctgacttt tcatcgtatt
     2821 cccaagcaga cccactaaag atagaatcta ggtcattggg ttcatcgcgc cagatatagt
     2881 agtctcgctc agggctatta ggattttcac aggcctctac aaaccaggca tgctcatccg
     2941 aggtatgatt gaccaccaag tccatgatga tacggatatc acgcttctta gcttctgcaa
     3001 tcagttgatc catatcctcc atggttccaa aaatcgttgc aatcgcttga taatcagcaa
     3061 tatcgtagcc attatcatcc atagggctgt cataaacggg agaaagccaa attgctgtga
     3121 ttcctagctt ggctagatag tccaacttac tggtaattcc tggcaaatcg ccaattccat
     3181 ctccattact atccataaaa ctctttggat agacttgata gactacggca ttgtgccacc
     3241 atttttcttg catcttctta cctcattatt ttcataatct atagtctatg atagcacttt
     3301 ttaaaatttt gtgcaagcgt ttgcttaatc tttttaattt cttttttagc tccgtagttt
     3361 cctaacttcc aattttttat tataatagag tccagaggta aaaaaatgaa aaaacaagct
     3421 tttagttctg aacaatattt gaatttacaa cgcgaccata ttttggagcg cattaaccaa
     3481 tttgacggca agctctactt agagtttggc ggtaaaatgt tagaagattt ccacgctgct
     3541 cgtgtccttc ctggttatga acctgacaac aaaatcaagc tcttgcaaga attgaaagag
     3601 caggttgagg ttgtgattgc cattaatgct agcaacattg aacattccaa agcacgtggc
     3661 gacttaggca tttcttatga ccaagaagtt cttcgtttga ttgacaaatt caatgaatta
     3721 gggatttttg ttggttccgt tgtcattaca caatacgctg gccaacccgc tgcagatgcc
     3781 ttccgcaatc aacttgagaa aaacggaatt gattcttatc ttcattatcc aatcaaagga
     3841 tatccgacgg atatggatca catcatttcc ccagaaggca tgggcaaaaa cgactacatc
     3901 aaaaccagtc gcaacttgat tgtcgtaacc gctcctggac ccggttctgg aaaattggca
     3961 acgtgtatgt ccaatatgta ccacgaccaa atcaatggca tcaagtctgg ctacgctaaa
     4021 tttgaaacct tccctgtttg gaatcttccc cttcatcacc cagttaactt ggcttatgaa
     4081 gctgccacag ctgaccttga tgatgtcaac atgattgacc ccttccatct tcaaacctat
     4141 ggagaaacca ctgtcaacta caaccgtgat atcgaaatct tcccagtgct caagcgcatg
     4201 ttggaacgta ttctcggaaa atcaccatac gcttcaccga cagatatggg tgtcaacatg
     4261 gttggtttcg ctattacaga tgacgaggct gctgtcgaag cttctaaaca agaaatcatc
     4321 cgccgttact atcaaacagt tcttgacttc aaagctgaaa aagttggcga agctgccgtc
     4381 aagaaaattg agttactcat gaacgacctc ggtatcacac ctgcagaccg taaggttgct
     4441 gtcgttgcgc gccaaaaagc agaagaaact ggtggaccag ccctagcctt tgaattgcca
     4501 aatggggaaa tcatcactgg taagaactca gaactctttg gccctacagc cgctgccttg
     4561 atcaatgcca tcaaaaaatc agctgacatc gctaaagaag taaaactaat cgagcctgaa
     4621 gttgttaagc caatccaagg tcttaaaatc gatcatctcg gtagccgcaa tccacgcctt
     4681 cattcaaatg aaatcctgat tgcacttgct atcacagcta cagaaaatcc tgatgctgcc
     4741 cgcgctatgg aagaactcgg caacctcaaa ggaagcgaag cccactcaac catcatcttg
     4801 actgatgaag acaagaatgt ccttcgtaaa ctgggtatca acgtaacctt tgacccatac
     4861 taccaatacg accgcttata tcgtaagtaa agatttcaac ctctccagcc tcggagaggt
     4921 tttctctctg tctcaggagc aacctttatg atataatgag agaagaaaac tgaaaggatt
     4981 taccatgtca aaagaagtta ttgtcgaaag ttttgaactt gaccacacca ttgtcaaagc
     5041 accctatgtt cgcttgattg gggaagaaac aggaccaaaa ggagacatca tctccaatta
     5101 tgatattcgc ttggtgcaac caaacgaaga ctctatccct actgccggcc ttcacactat
     5161 cgagcacctc ttagccaaac tcatccgtac ccgcattgac ggcatgattg actgttcacc
     5221 atttggttgc cgcacaggct tccacatgat tatgtgggga cgtcacacca gtgctaaaat
     5281 cgcagctgtt atcaaggatt cgctcaagga aatcgctgaa actactactt gggaagatgt
     5341 cccagggaca accatcgaat cttgcggaaa ctacaaggac cacagcctct tctctgctaa
     5401 agaatgggca aaactcatct tggaacaagg gatttcagat gatgcctttg aacgtcatgt
     5461 gattta
//
LOCUS       DAVBOG010000085         5438 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.086, whole genome shotgun sequence.
ACCESSION   DAVBOG010000085 DAVBOG010000000
VERSION     DAVBOG010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 5438)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5438)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5438
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.086"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ865_002060"
     CDS             complement(<1..1504)
                     /gene="glpK"
                     /locus_tag="VQ865_002060"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000076796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HET3136341.1"
                     /translation="MSQEKYIMAIDQGTTSSRAIIFNKKGEKVSSSQKEFTQIFPQAG
                     WVEHNANEIWNSVQSVIAGAFIESGVKPNQIEAIGITNQRETTVVWDKKTGLPIYNAI
                     VWQSRQTAPLAEQLKSQGYVEKFHEKTGLIIDAYFSATKVRWILDHVEGAQERAEKGE
                     LLFGTIDTWLVWKLTDGAAHVTDYSNAARTMLYNIKELKWDDEILEILNIPKAILPEV
                     RSNSEIYGKTAPFHFYGGEVPISGMAGDQQAALFGQLAFEPGMVKNTYGTGSFIIMNT
                     GEEMQLSENNLLTTIGYGINGKVYYALEGSIFIAGSAIQWLRDGLRMVENSPESEKYA
                     RDSHNNDEVYVVPAFTGLGAPYWNQNARGSVFGLTRGTSKEDFIKATLQSIAYQVRDI
                     IDTMQMDTQTAIQVLKVDGGAAMNNFLMQFQADILGIDIARAKNLETTALGAAFLAGL
                     SVGYWKDLDELKLLNETGELFEPSMNESRKEQLYKGWKKAVKATQVFAEID"
     gene            complement(1663..3090)
                     /locus_tag="VQ865_002061"
     CDS             complement(1663..3090)
                     /locus_tag="VQ865_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3136342.1"
                     /translation="MYLGDLMEKAECGQFSILSFLLQESQTTVKAVMEETGFSKATLT
                     KYVTLLNDKALDSGLELTIHSEDENLRLSIGAATKGRDIRSLFLESAVKYQILVYLLY
                     HQQFLAHQLAQELVISEATLGRHLAGLNQILSEFDLSIQNGRWRGPEHQIRYFYFCLF
                     RKVWSSQEWEGHMQKPERKQEIANLEEICGASLSAGQKLDLVLWAHISQQRLRVNACQ
                     FQVIEEKMRGYFDNIFYLRLLRKVPSFFAGQHIPLGVEDGEMMIFFSFLLSHRILPLH
                     TMEYILGFGGQLADLLTQLIQEMKKEELLGDYTEDHVTYELSQLCAQVYLYKGYILQD
                     RYKYQLENRHPYLLMEHDFKETAEEIFHALPAFQQGTDLDKKILWEWLQLIEYMAENG
                     GQHMRIGLDLTSGFLVFSRMAAILKRYLEYNRFITIEAYDPSRHYDLLVTNNPIHKKE
                     QTPVYYLKNDLDMEDLAGIRQLLFT"
     gene            3255..4127
                     /gene="hslO"
                     /locus_tag="VQ865_002062"
     CDS             3255..4127
                     /gene="hslO"
                     /locus_tag="VQ865_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000357853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HET3136343.1"
                     /translation="MDKIIKTISESGAFRAFVLDSTETVRTAQEKHQTQASSTVALGR
                     TLIASQILAANEKGNTKLTVKVLGSSSLGAIITVADTKGNVKGYVQNPGVDIKKTATG
                     EVLVGPFVGNGQFLVITDYGTGNPYNSITPLISGEIGEDLAFYLTESQQTPSAVGLNV
                     LLDEEDKVKVAGGFLVQVLPGAKKEEIARFEKRIQEMPAISTLLESDDHIEALLKAIY
                     GDEAYKRLSEEEIRFQCDCSHERFMNALASLPSSDLQEMKEEDHGAEITCQFCQTTYN
                     FDEKDLEELIRDKS"
     gene            4114..5094
                     /gene="dusB"
                     /locus_tag="VQ865_002063"
     CDS             4114..5094
                     /gene="dusB"
                     /locus_tag="VQ865_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HET3136344.1"
                     /translation="MTNLNTPFMIGNIEIPNRTVLAPMAGVTNSAFRTIAKELGAGLV
                     VMEMVSDKGIQYNNEKTLHMLHIDEGENPVSIQLFGSDEDSLARAAEFIQENTKTDIV
                     DINMGCPVNKIVKNEAGAMWLKDPDKIYSIINKVQSVLDIPLTVKMRTGWADPSLAVE
                     NALAAEAAGVSALAMHGRTREQMYTGHADLETLYKVAQALTKIPFIANGDIRTVQEAK
                     QRIEEVGADAVMIGRAAMGNPYLFNQINHYFETGEILPDLTFEDKMKIAYEHLKRLIN
                     LKGENVAVREFRGLAPHYLRGTSGAAKLRGAISQASTLAEIEALLQLEKA"
     gene            complement(5324..>5438)
                     /locus_tag="VQ865_002064"
     CDS             complement(5324..>5438)
                     /locus_tag="VQ865_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136345.1"
                     /translation="QWFKVSDKWYYVNGSGALAVNTTVDGYGVNANGEWVN"
BASE COUNT         1572 a         1287 c         1066 g         1513 t
ORIGIN      
        1 catcgatttc cgcaaagact tgagttgctt tcacagcctt cttccagccc ttgtagagtt
       61 gttccttgcg agattcgttc atagatggct caaagagttc tcctgtctcg ttcaagagtt
      121 tcaactcgtc caagtctttc cagtacccta ctgacaaacc tgctaggaag gccgctccta
      181 gagctgttgt ttccaagttt ttagcacgtg caatgtcaat gcctaaaata tccgcctgga
      241 actgcatgag gaagttgttc atggctgcac caccatccac cttcagtact tgaatggcgg
      301 tctgagtatc catttgcatg gtgtcgatga tgtcacgcac ttgataagca atagattgca
      361 aagtcgcctt gataaagtct tctttgcttg ttccacgagt caaaccaaag acggaaccac
      421 gagcattttg gttccagtat ggagcgccta gacctgtaaa ggctggaacg acataaactt
      481 catcgttgtt gtgagaatca cgagcgtatt tttcagattc tggtgaattt tcaaccatgc
      541 gaagaccgtc acgaagccac tgaatagcac ttcctgcgat gaagatagaa ccttccaagg
      601 cataataaac cttaccgttg attccgtaac caatggttgt caagaggttg ttttcagaca
      661 actgcatctc ttccccagta ttcatgatga tgaaagagcc tgttccataa gtattcttaa
      721 ccatacctgg ctcaaaagcc aactgtccaa agagggctgc ttgttggtcc ccagccatac
      781 ctgagattgg cacctctcca ccgtagaaat ggaatggagc tgtcttgccg tagatttcgg
      841 agttagaacg aacttctgga agtatagcct tcggaatgtt aaggatttcc aaaatctcat
      901 catcccattt gagttcttta atgttataaa gcatggtacg agctgcattt gagtagtcag
      961 tcacgtgagc cgcaccgtca gtcaatttcc aaaccaacca agtatcgata gtaccaaaga
     1021 gcaattcccc tttttctgct cgctcttgag caccttctac atgatccaaa atccaacgaa
     1081 ccttggtagc agagaagtaa gcatcaataa tcaaaccagt cttttcatgg aatttttcca
     1141 cataaccttg gctttttagt tgctcagcca aaggtgctgt ctggcgtgac tgccaaacga
     1201 tagcattgta gataggaagt cctgttttct tatcccagac aaccgttgtt tcacgttggt
     1261 tggtaatccc gattgcctcg atttgatttg gcttgacacc actttcgatg aaagcacccg
     1321 caataactga ctgaacagag ttccaaattt cattggcatt gtgctcaacc caacctgctt
     1381 gagggaaaat ctgggtaaac tctttttgac tcgagctaac cttttcccct tttttgttga
     1441 aaatgatggc acgagaactt gtagttccct ggtcaatggc catgatgtat ttttcttgtg
     1501 acatgtactg tcctcctgat aaagatcttg aggtgtttcc tctttacact tactagtata
     1561 caaaataaag cgctttcttg tttatcaact ttttttaatt tttaaaaaaa tgtgaggaga
     1621 ttgtgtgaat ttcacaaaaa agacctggat taaccaagcc ttttaagtga ataataactg
     1681 acgaatccct gccaaatctt ccatatccaa gtcatttttt aaataataga ctggtgtctg
     1741 ttccttctta tgaatagggt tattggtaac cagcaaatca taatgccgac tagggtcata
     1801 agcttcaatg gtaataaaac gattgtattc caaataccgt ttcaaaatgg ctgccatcct
     1861 tgaaaagaca agaaaaccag atgtcaaatc cagaccaatc cgcatatgct ggccaccgtt
     1921 ttcagccata tattcgatta actggagcca ttcccagaga atcttcttat ctaaatctgt
     1981 cccctgttga aaagcaggta gagcatgaaa aatctcctct gctgtctctt taaaatcatg
     2041 ttccatcagt aaatatggat gacgattctc taactggtac ttgtagcgat cctgtaaaat
     2101 atagccctta tagagataga cttgagcaca aagctgactg agttcatagg tgacatggtc
     2161 ctctgtataa tcccccaata gttcctcctt cttcatttct tgaatcaatt gcgtcagtaa
     2221 atctgccaac tgccctccaa aaccaagaat atactccata gtatgaagag gaagaatgcg
     2281 atgagatagg agaaaagaga agaatatcat catctcacca tcctcaactc ctagtggaat
     2341 atgttgccca gcaaaaaagg acggaacctt tctcagcaaa cgaagataga agatattgtc
     2401 aaaataccct cgcattttct cttctataac ttgaaactga caagcattga cccgaagacg
     2461 ttgttgactg atgtgagccc agagaaccaa gtccaatttc tgccccgcag acaaacttgc
     2521 accgcagatt tcctctaaat tggcaatctc ctgttttctc tctggtttct gcatgtgacc
     2581 ttcccattcc tgactcgacc agacctttcg gaaaagacag aaatagaaat agcgaatctg
     2641 atgctctgga cctcgccaac gtccattttg gatggataaa tcaaattctg acaaaatctg
     2701 atttaaacca gccaagtgac gaccaagcgt agcctcgcta atcactaatt cttgagccag
     2761 ctgatgggct aaaaactgtt ggtggtagag aagataaacc aaaatctggt atttaacagc
     2821 actctccaaa aacaagctcc gaatatctct ccccttggta gctgcaccga tagacagacg
     2881 cagattttca tcttctgagt gaatagtcag ttctaagcca ctatccaaag ccttgtcatt
     2941 gagcagggtg acatatttgg ttagggttgc ttttgaaaat cctgtttctt ccattacagc
     3001 cttgacggtc gtctgagact cttgtaatag aaaggaaagg attgaaaatt gaccacactc
     3061 ggctttctcc atcaaatctc ctaaatacat ttgttatccc tttcattttc taccttaagc
     3121 atagcataaa tcttacaaat gctaaaataa tctgtttctc tttttatttt catgctgatt
     3181 tcctggtcca ttatcctgaa aatcagtaaa cacacggctc cccctttggg catttttatg
     3241 ctaaaatagt agctatggat aaaattatta aaactatatc agaaagcgga gcctttcgtg
     3301 cttttgtcct tgatagcact gaaaccgtcc gcactgctca agaaaaacat caaacccaag
     3361 ctagctcaac tgtagcgctt ggtcgaactc ttatcgccag ccagattctc gcagccaatg
     3421 aaaaaggaaa taccaaactt acagttaagg tgttgggatc tagctctcta ggtgctatta
     3481 tcaccgtcgc tgataccaag gggaacgtca aaggctatgt tcaaaatcct ggtgttgaca
     3541 tcaaaaagac tgcgactggt gaagtcctag tcggaccttt tgttggaaat ggtcaattcc
     3601 tcgttatcac agactacggt actggaaatc cttacaactc tataactccc ctcatctctg
     3661 gagaaatcgg tgaagacctt gccttttacc ttactgaaag ccaacaaacg ccttcagcgg
     3721 tcggcctcaa tgtccttttg gacgaggaag acaaggtcaa ggttgcaggt ggtttcctag
     3781 ttcaagtctt gccaggagcc aagaaagaag agattgctcg ctttgaaaaa cgcatccaag
     3841 aaatgccagc tatctctact cttctcgaaa gcgacgacca tatcgaagcc ctcctcaagg
     3901 ctatctacgg ggacgaagcc tacaagcgtc tttctgaaga agaaatccgt ttccaatgtg
     3961 actgtagcca tgaacgcttt atgaacgctc ttgccagcct tccaagctca gacttacagg
     4021 aaatgaaaga ggaagaccac ggtgcagaaa tcacttgtca attctgccaa actacttaca
     4081 actttgatga aaaggacctg gaggaactca ttcgtgacaa atcttaatac accttttatg
     4141 attggcaata ttgagattcc caatcgtacc gttttagcgc ctatggctgg cgtgaccaac
     4201 tcagcctttc gtaccatagc aaaagagctc ggagctggac tcgttgtaat ggaaatggtc
     4261 tctgacaagg gaatccaata caacaacgaa aaaaccctgc acatgcttca tatcgatgag
     4321 ggcgaaaacc ctgtctctat ccaacttttt ggtagcgatg aagacagcct agcacgcgca
     4381 gcagaattca tccaagaaaa caccaagacc gatatcgtcg atatcaacat gggctgccct
     4441 gtcaacaaaa tcgtgaagaa cgaagctggt gctatgtggc tcaaggatcc tgacaagatc
     4501 tactctatca tcaacaaggt ccagtctgtc cttgatatcc cacttactgt caaaatgcgt
     4561 accggctggg cggacccatc tcttgcagta gaaaatgccc tcgctgctga ggctgcaggt
     4621 gtttctgccc tcgccatgca tggccgtacc cgtgaacaaa tgtatactgg ccacgcggac
     4681 cttgagaccc tttacaaggt tgcccaagct ctaaccaaga ttccattcat cgccaacggt
     4741 gatatccgta ctgtccaaga agccaagcaa cgcatcgaag aagttggtgc tgacgcagtc
     4801 atgattggcc gagctgccat gggaaatcct tacctcttca accaaatcaa ccattacttt
     4861 gaaacaggag aaatcctacc tgatttgaca tttgaagaca agatgaagat cgcctacgaa
     4921 cacttgaaac gattgattaa cctcaaagga gaaaacgtcg cagttcgtga attccgcggc
     4981 ctcgctcctc actatctccg tggaacatct ggcgctgcca aactccgtgg agccatttcg
     5041 caagctagca ccctagcaga gattgaagcc ctcttgcaat tggagaaggc ttaatagttt
     5101 aaaacccgta actctcttaa agagcctctt gaatgccgcc attctttcct catcaaaaaa
     5161 actccgtagt ctctagcgct ataaatccgg ctagagatta cagagttatt ttttaatcta
     5221 aacttcctac aagggtatat tatctactga aaggatatgg tatttgtagg gaatacttta
     5281 aagagttctt acaggaagtc agtattaact agttatatta ggtttagttt acccattcac
     5341 cattggcatt gactccatag ccatctacag ttgtgttgac tgcaagggca cctgagccat
     5401 tgacatagta ccatttatct gatactttga accattgg
//
LOCUS       DAVBOG010000086         4996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.087, whole genome shotgun sequence.
ACCESSION   DAVBOG010000086 DAVBOG010000000
VERSION     DAVBOG010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.087"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            298..1843
                     /locus_tag="VQ865_002065"
     rRNA            298..1843
                     /locus_tag="VQ865_002065"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
     gene            1895..1967
                     /locus_tag="VQ865_002066"
     tRNA            1895..1967
                     /locus_tag="VQ865_002066"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1928..1930,aa:Ala,seq:tgc)
     gene            2092..4993
                     /locus_tag="VQ865_002067"
     rRNA            2092..4993
                     /locus_tag="VQ865_002067"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT         1408 a         1017 c         1468 g         1103 t
ORIGIN      
        1 cgccttttca cggcggtaac acgggttcga atcccgtacg gactatggta tgttgcggtt
       61 ggaacacttg atgaaaaaaa gtttaaaaaa gcttaaaaat cttcaaaaaa gtgttgacaa
      121 gcgaaagcgg ctgtgatata ctaatatagt tgtcgcttga gagaagcgag tgacaaagac
      181 ctttgaaaac tgaacaagac gaaccaatgt gcagggcgct acaacataag ttgtagtact
      241 gaacaatgaa aaaaacaata aatctgtcag tgacagaaat gagtgagaac tcaaactttt
      301 aatgagagtt tgatcctggc tcaggacgaa cgctggcggc gtgcctaata catgcaagta
      361 gaacgctgaa ggaggagctt gcttctctgg atgagttgcg aacgggtgag taacgcgtag
      421 gtaacctgcc tggtagcggg ggataactat tggaaacgat agctaatacc gcataagagt
      481 agatgttgca tgacatttgc ttaaaaggtg cacttgcatc actaccagat ggacctgcgt
      541 tgtattagct agttggtggg gtaacggctc accaaggcga cgatacatag ccgacctgag
      601 agggtgatcg gccacactgg gactgagaca cggcccagac tcctacggga ggcagcagta
      661 gggaatcttc ggcaatggac ggaagtctga ccgagcaacg ccgcgtgagt gaagaaggtt
      721 ttcggatcgt aaagctctgt tgtaagagaa gaacgagtgt gagagtggaa agttcacact
      781 gtgacggtat cttaccagaa agggacggct aactacgtgc cagcagccgc ggtaatacgt
      841 aggtcccgag cgttgtccgg atttattggg cgtaaagcga gcgcaggcgg ttagataagt
      901 ctgaagttaa aggctgtggc ttaaccatag taggctttgg aaactgttta acttgagtgc
      961 aagaggggag agtggaattc catgtgtagc ggtgaaatgc gtagatatat ggaggaacac
     1021 cggtggcgaa agcggctctc tggcttgtaa ctgacgctga ggctcgaaag cgtggggagc
     1081 aaacaggatt agataccctg gtagtccacg ctgtaaacga tgagtgctag gtgttagacc
     1141 ctttccgggg tttagtgccg tagctaacgc attaagcact ccgcctgggg agtacgaccg
     1201 caaggttgaa actcaaagga attgacgggg gcccgcacaa gcggtggagc atgtggttta
     1261 attcgaagca acgcgaagaa ccttaccagg tcttgacatc cctctgacga ctctagagat
     1321 agagttttcc ttcgggacag aggtgacagg tggtgcatgg ttgtcgtcag ctcgtgtcgt
     1381 gagatgttgg gttaagtccc gcaacgagcg caacccctat tgttagttgc catcatttag
     1441 ttgggcactc tagcgagact gccggtaata aaccggagga aggtggggat gacgtcaaat
     1501 catcatgccc cttatgacct gggctacaca cgtgctacaa tggctggtac aacgagtcgc
     1561 aagccggtga cggcaagcta atctcttaaa gccagtctca gttcggattg taggctgcaa
     1621 ctcgcctaca tgaagtcgga atcgctagta atcgcggatc agcacgccgc ggtgaatacg
     1681 ttcccgggcc ttgtacacac cgcccgtcac accacgagag tttgtaacac ccgaagtcgg
     1741 tgaggtaacc gtaaggagcc agccgcctaa ggtgggatag atgattgggg tgaagtcgta
     1801 acaaggtagc cgtatcggaa ggtgcggctg gatcacctcc tttctaagga taaggaactg
     1861 cgcattggtc ttgtttagtc ttgagaggtc ttgtggggcc ttagctcagc tgggagagcg
     1921 cctgctttgc acgcaggagg tcagcggttc gatcccgcta ggctccattg gtgagagatc
     1981 accaagtaat gcacattgaa aattgaatat ctatatcaaa tagtaacaag aaaataaacc
     2041 gaaaacgctg tagtattaat aagagtttat gactgaaagg tcagaaaata aggttaagtt
     2101 aataagggcg cacggtggat gccttggcac taggagccga cgaaggacgt gacaaacgac
     2161 gatatgcctt gggtagctgt aagtaagcga tgatccatgg atttccgaat gggggaaccc
     2221 aacaggtaat acctgttacc cacatctgtt aaggatgtga ggaggaagac gcagtgaact
     2281 gaaacatcta agtagctgca ggaagagaaa gcaaaagcga ttgccttagt agcggcgagc
     2341 gaaacggcag aagggcaaac cgaagagttt actcttcggg gttgtaggac tgcaatgtgg
     2401 actcaaagat tatagaagaa tgatttggga agatcagcca aagagagtaa tagcctcgta
     2461 tttaaaatag tctttgtacc tagcagtatc ctgagtacgg cgggacacgt gaaatcccgt
     2521 cggaatctgg gaggaccatc tcccaaccct aaatactccc tagtgaccga tagtgaacca
     2581 gtaccgtgag ggaaaggtga aaagcacccc gggaggggag tgaaatagaa cctgaaaccg
     2641 tgtgcctaca acaagttcga gcccgttaat gggtgagagc gtgccttttg tagaatgaac
     2701 cggcgagtta cgttatgatg cgaggttaag ttgaagagac ggagccgtag ggaaaccgag
     2761 tctgaatagg gcgccttagt atcatgacgt agacccgaaa ccatgtgacc tacccatgag
     2821 caggttgaag gtgcggtaag acgcactgga ggaccgaacc agggcacgtt gaaaagtgct
     2881 tggatgactt gtgggtagcg gagaaattcc aaacgaactt ggagatagct ggttctctcc
     2941 gaaatagctt tagggctagc gtcgacatta gagattcttg gaggtagagc actgtttggg
     3001 tgaggggtcc atcccggatt accaatctca gataaactcc gaatgccaat gaattatggt
     3061 cggcagtcag actgcgagtg ctaagatccg tagtcgaaag ggaaacagcc cagaccacca
     3121 gctaaggtcc caaaataatt gttaagtgga aaaggatgtg gggttgcaca gacaactagg
     3181 atgttagctt agaagcagct attcattcaa agagtgcgta atagctcact agtcgagtga
     3241 ccctgcgccg aaaatgtacc ggggctaaaa caatttaccg aagctgtgga tacctttata
     3301 ggtatggtag gagagcgttc tatgtgtgat gaaggtatac cgtgaggagt gctggaacgc
     3361 atagaagtga gaatgccggt atgagtagcg aaagacaggt gagaatcctg tccaccgtaa
     3421 gactaaggtt tccaggggaa ggctcgtccg ccctgggtta gtcgggacct aaggagagac
     3481 cgaaaggtgt atccgatgga caacaggttg atattcctgt actagagtat gtagtgatgg
     3541 agggacgcag taggctaact aaagcagacg attggaagag tctgtctaag cagtgaggtg
     3601 tgaattgagt caaatgctta attctataac attgagctgt gatggggagc gaagtttagt
     3661 agcgaagtta gtgacgtcac actgccaaga aaagcttcta gcgtttaaac atactctacc
     3721 cgtaccgcaa accgacacag gtagtcgagg cgagtagcct caggtgagcg agagaactct
     3781 cgttaaggaa ctcggcaaaa tgaccccgta acttcgggag aaggggtgct gactttaagt
     3841 cagccgcagt gaataggccc aagcaactgt ttatcaaaaa cacagctctc tgctaaatcg
     3901 taagatgatg tatagggggt gacgcctgcc cggtgctgga aggttaagag gagtgcttag
     3961 cgtaagcgaa ggtatgaatt gaagccccag taaacggcgg ccgtaactat aacggtccta
     4021 aggtagcgaa attccttgtc gggtaagttc cgacccgcac gaaaggcgta atgatttggg
     4081 cactgtctca acgagagact cggtgaaatt ttagtacctg tgaagatgca ggttacccgc
     4141 gacaggacgg aaagacccca tggagcttta ctgcagtttg atattgagtg tctgtaccac
     4201 atgtacagga taggtaggag tctaagagat cgggacgcca gtttcgaagg agacgctgtt
     4261 gggatactac ccttgtgtta tggccactct aacccagata ggtgatccct atcggagaca
     4321 gtgtctgacg ggcagtttga ctggggcggt cgcctcctaa aaggtaacgg aggcgcccaa
     4381 aggttccctc agaatggttg gaaatcattc gcagagtgta aaggtataag ggagcttgac
     4441 tgcgagagct acaactcgag cagggacgaa agtcgggctt agtgatccgg tggttccgta
     4501 tggaagggcc atcgctcaac ggataaaagc taccctgggg ataacaggct tatctccccc
     4561 aagagttcac atcgacgggg aggtttggca cctcgatgtc ggctcgtcgc atcctggggc
     4621 tgtagtcggt cccaagggtt gggctgttcg cccattaaag cggcacgcga gctgggttca
     4681 gaacgtcgtg agacagttcg gtccctatcc gtcgcgggcg taggaaattt gagaggatct
     4741 gctcctagta cgagaggacc agagtggact taccgctggt gtaccagttg tcttgccaaa
     4801 ggcatcgctg ggtagctatg tagggaaggg ataaacgctg aaagcatcta agtgtgaaac
     4861 ccacctcaag atgagatttc ccatgattat atatcagtaa gagccctgag agatgatcag
     4921 gtagataggt tagaagtgga agtgtggcga cacatgtagc ggactaatac taatagctcg
     4981 aggacttatc caaagt
//
LOCUS       DAVBOG010000087         4645 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.088, whole genome shotgun sequence.
ACCESSION   DAVBOG010000087 DAVBOG010000000
VERSION     DAVBOG010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4645)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4645)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4645
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.088"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(80..517)
                     /locus_tag="VQ865_002068"
     CDS             complement(80..517)
                     /locus_tag="VQ865_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004269962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HET3136346.1"
                     /translation="MSQEFINPSDGVIRQYLATSKTLAVVGLSDREETTSNRVTKEMQ
                     ARGYKIIPVNPKAAGGEILGEKAYASLAEIPFPVDIVNVYRRSEFLPDVARDFLKADA
                     KIFWAQLGLESLKAKEILRDGGCDDIVMNRCIKREHTRLIEEA"
     gene            complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ865_002069"
     CDS             complement(602..3235)
                     /gene="polA"
                     /locus_tag="VQ865_002069"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014932012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HET3136347.1"
                     /translation="MDKKKLLLIDGSSVAFRAFFALYQQLDRFKNAAGLHTNAIYGFQ
                     LMLSHLLERVEPSHILVAFDAGKTTFRTEMYADYKGGRAKTPDEFREQFPFIRELLDH
                     MGIRHYELAQYEADDIIGTLDKLAEQDGFDITIVSGDKDLIQLTDEHTVVEISKKGVA
                     EFEAFTPDYLMEEMGLTPAQFIDLKALMGDKSDNIPGVTKVGEKTGIKLLLEHGSLEG
                     IYENIDGMKTSKMKENLINDKEQAFLSKTLATIDTKAPIAIGLEDLVYSGPDVENLGK
                     FYDEMGFKQLKQALNVSSADVSESLDFTIVDQISQDMLSEESIFHFELFGENYHTDNL
                     VGFAWSCGDKLYATDKLELLQDPIFKDFLEKTSLRVYDFKKVKVLLQRFGVDLQAPAF
                     DIRLAKYLLSTVEDNEIATIASLYGQTYLVDDETFYGKGVKKAIPEREKFLEHLACKL
                     AVLVETEPILLEKLSENGQLELLYDMEQPLAFVLAKMEIAGIMVKKETLLEMQAENEL
                     VIEKLTQEIYELAGEEFNVNSPKQLGVLLFEKLGLPLEYTKKTKTGYSTAVDVLERLA
                     PIAPIVKKILDYRQIAKIQSTYVIGLQDWILADGKIHTRYMQDLTQTGRLSSVDPNLQ
                     NIPARLEQGRLIRKAFVPEWEDSVLLSSDYSQIELRVLAHISKDEHLIKAFQEGADIH
                     TSTAMRVFGIERPDNVTANDRRNAKAVNFGVVYGISDFGLSNNLGISRKEAKAYIDTY
                     FERFPGIKNYMDEVVREARDKGYVETLFKRRRELPDINSRNFNIRGFAERTAINSPIQ
                     GSAADILKIAMIQLDKALVAGGYQTKMLLQVHDEIVLEVPKSELVEMKKLVKQTMEEA
                     IQLSVPLIADENEGATWYEAK"
     gene            3491..3841
                     /locus_tag="VQ865_002070"
     CDS             3491..3841
                     /locus_tag="VQ865_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001811778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family transposase"
                     /protein_id="HET3136348.1"
                     /translation="MLRHPGISPTNDLIAKKIFSNPEITCQFIRDMLDLPAKNVTILE
                     GSDIHVLLSMPYSVQDFYTSIDVLAELDNGTQVIIEIQVHHQNFFINHLWAYLCSQVN
                     QNLEKIRQREGDTH"
     gene            4056..4160
                     /locus_tag="VQ865_002071"
     CDS             4056..4160
                     /locus_tag="VQ865_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000233180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein CinA"
                     /protein_id="HET3136349.1"
                     /translation="MVGVFRQQALYPATATSHYPSKSTAGLQELVRGG"
     gene            4165..4398
                     /locus_tag="VQ865_002072"
     CDS             4165..4398
                     /locus_tag="VQ865_002072"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136350.1"
                     /translation="MFSQLRMREEQALLAQDYALETARAGGIEQGLERGKVEGREERK
                     LFAFLDIVRQDLLTSEVASQQLGMSVSEFEALL"
BASE COUNT         1423 a         1108 c          855 g         1259 t
ORIGIN      
        1 gcccgcggct agtttcctag tttgctcttt gattttcatt gagtataaca caaaaggtag
       61 cccatcagct acctttttct tatgcttcct caatcaagcg agtatgttct ctcttgatac
      121 agcgattcat cacgatatca tcacatccac catcacgcaa aatctctttc gcttttaaac
      181 tttcaagtcc tagctgtgcc caaaaaatct tggcatcagc tttgagaaaa tcacgcgcca
      241 catcgggcag aaattcactg cgacgataaa cattgacaat atctacagga aaaggaattt
      301 cagcgaggct agcataagcc ttttcaccca agatttcgcc acctgccgcc ttgggattga
      361 ctgggatgat tttatagccc cgagcctgca tttcctttgt cactcgattg ctggttgttt
      421 cttcacggtc agacaaaccc accacagcaa gggttttact cgttgcgaga tactgacgaa
      481 tcacgccatc acttggattg ataaattctt gactcataga aaacctcctt tttcatcagt
      541 atagcacatt ttgaaaaggt ttgcagaatt ctactacaaa aaaggaggac tagccccctt
      601 tttatttagc ctcgtaccag gttgcccctt cattctcatc tgcgataaga ggaacactga
      661 gttgaatggc ttcttccatg gtttgtttca ccaatttttt catctctacc aattcagatt
      721 taggcacttc aaggacgatt tcatcgtgca cttgtaacag catcttagtc tgataaccac
      781 ctgcaaccaa ggctttatcc agctgaatca tggcaatctt gagaatatct gctgccgaac
      841 cctggatagg tgagttgata gcagttcgct ccgcaaaacc acgaatattg aagttgcgcg
      901 aattgatatc tggcaactca cggcgacgct taaagagggt ctctacatag cccttatcac
      961 gcgcctcccg caccacttca tccatgtagt ttttaatacc tggaaaacgt tcaaagtagg
     1021 tatcaatgta ggctttggct tccttacgac taattcccaa attattagac aagccaaagt
     1081 ctgaaatccc ataaaccact ccaaagttaa ctgccttggc attgcgacga tcatttgcag
     1141 tcacattatc aggacgctca atgccaaaga cccgcatggc tgtcgaagta tggatatctg
     1201 ccccctcttg gaaggcctta atcaagtgct catccttaga aatatgcgcc aaaacgcgca
     1261 attcaatctg tgaatagtca gagctgagta gcacactatc ctcccactct ggcacaaaag
     1321 ccttccgaat caagcgccct tgttccaatc gggcaggaat attttgcaag tttggatcca
     1381 cactagacaa acgcccggtc tgggtcaaat cctgcatata gcgagtatga atctttccat
     1441 cagccaaaat ccagtcctgc aagccaatta cataagtaga ttgaatctta gcaatttgac
     1501 ggtaatccag gattttctta acaatcggag caataggagc gagacgctcc aacacatcca
     1561 ctgctgtcga ataacctgtc ttggttttct tagtgtattc tagaggaagt cccaatttct
     1621 caaagagaag cacgcccaac tgcttaggcg agttgacatt aaactcctca ccagccagct
     1681 cgtaaatctc ttgagtcagt ttttcaatga caagctcatt ttcagcctgc atctcaagca
     1741 aggtctcttt cttgaccata atcccagcaa tttccatctt ggcaaggaca aaagccagag
     1801 gttgctccat atcataaaga agctctaatt gcccattttc gctgagtttt tcaagtaaaa
     1861 taggctctgt ttctaccaaa acagcaagtt tacaagctaa gtgttccaag aatttctcac
     1921 gttcaggaat ggccttttta acacccttac cgtagaaagt ttcatcatca accaagtaag
     1981 tctgaccata aagactagcg atggtcgcaa tttcattgtc ctccacagtc gaaaggaggt
     2041 atttagccaa acggatgtca aaagcaggcg cctgcaaatc cacaccaaaa cgttgcaaaa
     2101 gaactttaac cttcttaaag tcataaactc tcagagatgt tttttctaag aaatccttga
     2161 aaatcgggtc ttgcaacagc tcaagcttgt ctgtggcata gagcttatcc ccacaagacc
     2221 aggcaaatcc aaccaaatta tccgtatggt aattctcacc aaaaagctca aagtggaaga
     2281 tagactcttc actcagcata tcttgactga tttggtcaac aatagtaaaa tccaaactct
     2341 cagacacatc agctgacgac acatttaaag cctgctttag ctgtttgaag cccatctcat
     2401 cgtagaattt cccaagattt tcaacatctg gaccactata gaccaagtcc tctaaaccaa
     2461 tcgcaatcgg tgccttggta tcaatggtcg ctagtgtttt agataaaaag gcctgttcct
     2521 tgtcattgat gagattttcc ttcatcttag aagtcttcat tccatcaata ttttcataaa
     2581 tcccctcaag cgaaccatgc tccagcaaga gcttaatacc cgtcttttca ccgactttgg
     2641 tcaccccagg gatattatcc gacttatcac ccatgagcgc cttgagatcg ataaactgag
     2701 ctggtgtgag gcccatttct tccatgaggt aatctggcgt aaaggcctca aactcagcca
     2761 cacctttctt ggaaatttca accaccgtat gctcatccgt cagctgaatc aaatccttgt
     2821 ccccactgac aatggtaata tcaaaaccat cctgctctgc tagcttatcc agcgtcccaa
     2881 tgatgtcatc cgcctcatac tgagccagct catagtgacg aatccccata tgatccagca
     2941 actcacgaat gaaaggaaat tgctcacgaa actcatcagg agtcttggcc cgaccaccct
     3001 tatagtccgc atacatctct gtccggaagg tcgtctttcc cgcatcaaaa gccaccaaaa
     3061 tatgactcgg ctcaacccgc tccaacaaat gactcaacat caactgaaaa ccataaatcg
     3121 cattggtatg caaaccagcc gcattcttaa aacggtccaa ctgctgatac agcgcaaaaa
     3181 acgcccgaaa agctacagaa gacccatcaa tcaataataa ttttttctta tccatacacc
     3241 cattataaag gaaagaatca aaaaatacca ttgggaagag ctagagcaag tatttttcaa
     3301 actttttccg aataaataga tagagccaga gaatttagta aacctagatt taaaaatgtg
     3361 ctataatata gtatattgaa tctataatag tacaccttga ctgctaaaat atttctataa
     3421 attaatttga ctttcctgat agagttattc acatcttatt tcaactcact atagaaggag
     3481 gaataggagg attctcagac atccgggcat cagcccaact aatgatttga ttgctaagaa
     3541 aatattcagc aatccagaaa tcacttgtca atttattcgc gatatgctgg acttgccagc
     3601 aaaaaatgtg accattttgg agggaagcga tattcacgta ttactctcca tgccttactc
     3661 ggtgcaggat ttttatacca gtatagacgt cttggcggag ttggataacg gtactcaagt
     3721 aattattgag attcaagtcc atcatcagaa ttttttcatc aatcacttgt gggcttacct
     3781 gtgcagtcag gttaatcaaa atcttgaaaa aattcgtcag cgagaaggtg atactcacta
     3841 gatctacaaa cacatcgctc ctgtttacgt cattgctatc gtggatagta attatttctc
     3901 agatgacctg gcttttcata gctttagtat gcgcgaagac acaacaggtg aggtattggc
     3961 gattaccaac aatggacagg aaaaccatct ggttaagatg gcattcttgg aattaaaaaa
     4021 tacagagaaa ccagcaaaga caaggttcgc aagccatggt tggagttttt cggcaacaag
     4081 ccctttaccc agcaaccgca acgagccatt acccaagcaa atcaactgct ggactacaag
     4141 agctggtccg aggaggatag gaaaatgttt agtcaactac gtatgcgaga agaacaagcc
     4201 ttgttagcgc aggactatgc cttggaaact gctagggcgg gaggtattga acaaggctta
     4261 gagcgtggga aagttgaagg aagggaagaa aggaaacttt ttgccttcct agacatagta
     4321 cgccaagatc ttctgacttc tgaggttgcc agccagcaat taggtatgtc agtatctgaa
     4381 tttgaggcac tgttgtaaaa tggctccata atatccatag tgggtaaatc ccctatggat
     4441 attatggagc ctattttgtg tagaaaaaaa gtcccatatg acctataatg aaaagcgaca
     4501 aaacaactca ttagaaagaa tcatatggaa caattacatt ttatcacaaa attactagac
     4561 attaaagacc ctaatgtcca gattttaaac atcatcaata aggatacaca caaggaaatc
     4621 atcgccaaac tggactacga cgccc
//
LOCUS       DAVBOG010000088         4602 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.089, whole genome shotgun sequence.
ACCESSION   DAVBOG010000088 DAVBOG010000000
VERSION     DAVBOG010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4602
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.089"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..266
                     /locus_tag="VQ865_002073"
     CDS             <1..266
                     /locus_tag="VQ865_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase family
                     protein"
                     /protein_id="HET3136351.1"
                     /translation="YLNANGAMATGWAKVNGSWYYLNANGSMATGWVKDGDTWYYLEA
                     SGAMKASQWFKVSDKWYYVNGLGALAVNTTVDGYEVNANGEWV"
     gene            667..1788
                     /gene="mnmA"
                     /locus_tag="VQ865_002074"
     CDS             667..1788
                     /gene="mnmA"
                     /locus_tag="VQ865_002074"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006153390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HET3136352.1"
                     /translation="MSDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVVAVADQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMTLGADYVATGHYARVARDEDGTVHMLRGVDNGKDQTYFLSQLS
                     QEQLQKTMFPLGHLEKPEVRKLAEEAGLSTAKKKDSTGICFIGEKNFKNFLSNYLPAQ
                     PGRMMTVDGRDMGEHAGLMYYTIGQRGGLGIGGQHGGDNAPWFVVGKDLSKNILYVGQ
                     GFYHDSLMSTSLEASQVHFTREMPEEFTLECTAKFRYRQPDSKVTVHVKGDKAEVIFA
                     EPQRAITPGQAVVFYDGEECLGGGLIDNAYRDGQVCQYI"
     gene            1929..2384
                     /locus_tag="VQ865_002075"
     CDS             1929..2384
                     /locus_tag="VQ865_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3136353.1"
                     /translation="MTQQDFRTKVDNTVFGVRATALILQNHKLLVTKDKGKYYTIGGA
                     IQVNESTEDAVVREVKEELGVKAQAGQLAFVVENRFEQDGVSYHNIEFHYLVDLLEDA
                     PLTMQEDEKRQPCEWIDLDKLEDIQLVPAFLKTALPDWEGQLRHIHLEE"
     gene            2394..4307
                     /gene="mnmG"
                     /locus_tag="VQ865_002076"
     CDS             2394..4307
                     /gene="mnmG"
                     /locus_tag="VQ865_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HET3136354.1"
                     /translation="MTYHFTEEYDIIVIGAGHAGVEASLAASRMGCKVLLATINIEML
                     AFMPCNPSIGGSAKGIVVREVDALGGEMAKTIDKTYIQMKMLNTGKGPAVRALRAQAD
                     KELYSKEMRKTVENQENLTLRQTMIDEILVEDGKVVGVRTATHQEYAAKAVIVTTGTA
                     LRGEIIIGDLKYSSGPNHSLASINLADNLKELGLEIGRFKTGTPPRVKASSINYDVTE
                     IQPGDEVPNHFSYTSRDEDYVKDQVPCWLTYTNGTSHEIIQNNLHRAPMFTGVVKGVG
                     PRYCPSIEDKIVRFADKERHQLFLEPEGRNTEEVYVQGLSTSLPEDVQRDLVHSIKGL
                     ENAEMMRTGYAIEYDMVLPHQLRATLETKKISGLFTAGQTNGTSGYEEAAGQGIIAGI
                     NAALKIQGKPELILKRSDGYIGVMIDDLVTKGTIEPYRLLTSRAEYRLILRHDNADMR
                     LTEMGREIGLVDDERWARFEIKKNQFDNEMKRLDSIKLKPVKETNAKVEEMGFKPLTD
                     AVTAKEFLRRPEVSYQDVVAFIGPAAEDLDDKIIELIETEIKYEGYISKAMDQVAKMK
                     RMEEKRIPANIDWDDIDSIATEARQKFKLINPETIGQASRISGVNPADISILMVYLEG
                     KNRSISKTLQKSK"
BASE COUNT         1336 a          932 c         1123 g         1211 t
ORIGIN      
        1 actacctaaa cgctaacggt gctatggcaa caggttgggc taaagtcaac ggttcatggt
       61 actacctcaa cgctaacggt tcaatggcaa caggttgggt gaaagatgga gatacctggt
      121 actatcttga agcatcaggt gctatgaaag caagccaatg gttcaaagta tcagataaat
      181 ggtactatgt caatggctta ggtgcccttg cagtcaacac aactgtagat ggctatgaag
      241 tcaatgccaa tggtgaatgg gtttaagccg attaaattaa atcatgttaa gaacatttga
      301 cattttaatt ttgaaacaaa gataaggttc gattgaataa atttatgttc gtattcttta
      361 ggtacctatc ttatgatttc aggaaatgtc attaaaaaaa cgactccttt tctctaactt
      421 gaaaaataga ttagagaaaa tgggttgttt tatttattat agttatttga atgaagataa
      481 gaagaaggta tactcacatc attcacataa tctgtatatt gactataagt tttaaaaaac
      541 aatttttaag ctcttccttg tcttctctaa ccaagcgtgt tataatgaat actgctcaag
      601 cgaccttcaa tcgtgaagca cacacgacct tcaatcgtga ataaacgaat agatgggaga
      661 cttaccatga gtgataactc taaaacacgt gttgtcgtgg ggatgagtgg tggtgttgat
      721 tcgtcggtga cggctctttt gctcaaggag cagggctacg atgtgatcgg tatcttcatg
      781 aagaactggg atgacacaga tgaaaacggc gtctgtacgg cgaccgaaga ttacaaggat
      841 gtggttgcgg tggcagacca gattggcatt ccctactact ctgtcaattt tgaaaaagag
      901 tactgggacc gcgtttttga gtatttccta gcggaatacc gtgcagggcg cacgccaaat
      961 ccggacgtta tgtgcaacaa ggaaatcaag ttcaaggcct ttttggacta tgccatgacc
     1021 ttgggggcag actatgtagc gactgggcat tatgctcgag tggcgcgtga tgaggacggc
     1081 actgttcaca tgcttcgtgg cgtggacaat ggcaaggacc agacctattt cctcagccaa
     1141 ctttcgcaag aacaacttca aaaaaccatg ttcccactag gacatttgga aaagcctgaa
     1201 gttcgaaaac tagcagaaga agcaggcctt tcgactgcta agaagaaaga ctcgacaggg
     1261 atttgcttta tcggagaaaa gaactttaaa aacttcctca gcaactacct gccagctcag
     1321 cctggtcgca tgatgactgt ggatggtcgc gatatgggcg agcatgcagg tctgatgtat
     1381 tatacaatcg gtcagcgtgg cggactcggt atcggtgggc aacacggcgg tgacaatgcc
     1441 ccttggttcg ttgtcggaaa agatctaagc aagaatattc tctatgtagg acaaggattc
     1501 taccatgatt cgctcatgtc aactagccta gaagccagtc aagtccactt tactcgtgaa
     1561 atgccagaag agtttacgct agaatgtacg gctaaattcc gttaccgtca gcctgactct
     1621 aaggtgaccg tccatgtcaa aggagacaag gcagaggtca tctttgcgga accacaacgc
     1681 gcgattacac caggccaggc agttgtcttt tacgatggcg aagagtgtct aggtggtggt
     1741 ttgattgaca atgcttaccg cgatggacaa gtttgtcagt acatttagat tgacaaattt
     1801 tctcaatttg ctacaataat aacagcaata gaaatgatgg tcaaagctca tggatgttgc
     1861 aggctttttt gtcctgcact tctttggagt tttgactgtt tttgtgtcgt ttaagggaaa
     1921 ggacaagaat gactcaacaa gactttcgga caaaagtaga caatacggtt tttggtgttc
     1981 gggcgacagc tttgattctt caaaatcaca agcttctagt caccaaagac aagggcaagt
     2041 attacactat cggcggtgcg attcaagtca atgaaagcac ggaagacgcg gtagtccgtg
     2101 aagtgaagga agaactgggt gtcaaagctc aagctgggca gctagctttt gtggttgaaa
     2161 atcgttttga acaggacggt gtttcctatc acaatatcga gtttcattat ctggtggact
     2221 tacttgagga tgccccattg accatgcagg aagatgagaa aaggcagccc tgtgagtgga
     2281 ttgacttgga taagcttgag gatatccagc tagttccagc ctttttaaaa acggccctac
     2341 cagattggga aggccaacta agacacattc atcttgagga ataggagaga aacatgactt
     2401 atcattttac tgaagaatac gatattattg taattggtgc gggacacgct ggggttgagg
     2461 cttccttggc cgctagccgt atgggctgta aggtcctgct tgcgaccatc aatattgaaa
     2521 tgctggcttt catgccttgt aatccctcta tcggtggttc tgctaagggg attgtcgtac
     2581 gtgaagtcga tgccctcggt ggcgagatgg ccaagaccat tgacaagact tacatccaga
     2641 tgaagatgct caacacaggg aagggcccag ccgttcgtgc ccttcgtgcg caggctgata
     2701 aggaacttta ctctaaggaa atgcgcaaga cagttgaaaa tcaagaaaat ctgacccttc
     2761 gtcaaaccat gattgatgag attttggtgg aagatggcaa ggttgtcggt gtgcgtacag
     2821 ccacccatca agaatatgct gctaaggctg ttattgtgac gacagggact gctctccgtg
     2881 gggaaattat catcggagac ctcaagtact catcaggtcc taaccacagc ttggcttcta
     2941 ttaacctagc tgacaatctc aaggaactgg gtctcgaaat cggtcgtttc aagacaggaa
     3001 cccctccacg tgtcaaggct tcttctatca attacgatgt gacggaaatt cagccaggag
     3061 acgaagtgcc taatcatttc tcatacactt cacgtgatga ggattatgtc aaagatcaag
     3121 tgccatgctg gttgacctat accaatggta ccagtcatga gattatccaa aacaacctcc
     3181 accgtgcgcc tatgtttaca ggtgtggtca agggagtggg gcctcgttac tgtccgtcga
     3241 ttgaagacaa gattgtgcgc tttgcggaca aggaacgtca ccaactcttc cttgagccag
     3301 aagggcgcaa tactgaggaa gtctatgttc aaggactttc aaccagtctg cctgaggatg
     3361 tccagcgtga cttggttcat tccatcaaag gtttggaaaa tgcagagatg atgcggacag
     3421 gttatgctat tgagtatgat atggtcttgc ctcatcagtt gcgtgcgact ttggaaacca
     3481 agaaaatctc aggtctcttc actgctggtc agacaaatgg aacatcaggt tatgaagaag
     3541 ctgctggcca agggattatc gcgggtatca atgcggctct gaaaatccaa ggtaaacctg
     3601 agttgattct aaaacgaagt gacggttata tcggggtgat gatcgacgac ttggtgacca
     3661 agggaaccat tgaaccttac cgtctcttga ccagtcgtgc tgaataccgt ctcattcttc
     3721 gtcatgacaa tgctgatatg cgcttgactg agatgggacg cgagattggc cttgtggatg
     3781 atgaacgctg ggctcgtttt gaaatcaaga aaaatcaatt tgataatgag atgaaacgcc
     3841 tagacagtat caaactcaag ccagtcaagg aaaccaatgc taaggttgag gaaatgggct
     3901 tcaagccgtt gacagatgcg gtgacagcca aagaattcct tcgccgtcca gaagtttctt
     3961 accaagatgt ggtggccttc atcggaccag ctgcagaaga cttggatgac aagattatcg
     4021 aattgattga aacagaaatc aagtacgaag gctatatttc aaaagccatg gatcaggttg
     4081 ccaagatgaa acgtatggaa gaaaaacgca ttccagccaa tattgactgg gatgacatcg
     4141 attctattgc gacggaagct cgtcagaagt tcaaactcat caatccagaa accatcggcc
     4201 aagccagccg tatttcggga gtaaacccag cagatatttc tattttgatg gtgtatctgg
     4261 aaggtaaaaa tcgtagtatt tctaaaactc ttcaaaaatc aaaatgatac gtcgtcggct
     4321 tcttacgaat gagttcaaag cttggctttg attcatctcc agcctcccat agttccccga
     4381 actatgggag ctaactcaag ttatgcattt tcctagcctt ctggtctgat tttcattgag
     4441 ttttaatctc aaaagaaagc atagagaaaa acagctccga agacggagct gttttgttga
     4501 cttgtactca atgaaaatca aagagcaaac taggaagcta gccgtaggtt gctcaaagca
     4561 ctgctttgag gttgtagata gaactgacga agtcagctca aa
//
LOCUS       DAVBOG010000089         4347 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.090, whole genome shotgun sequence.
ACCESSION   DAVBOG010000089 DAVBOG010000000
VERSION     DAVBOG010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.090"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(60..659)
                     /locus_tag="VQ865_002077"
     CDS             complement(60..659)
                     /locus_tag="VQ865_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HET3136355.1"
                     /translation="MKVLVAEDQSMLRDAMCQLLTLQPDVESVLQAKNGQEAIQLLEK
                     ESVDIAILDVEMPVKTGLEVLEWIRSERLETKVVVVTTFKRPGYFERAVKAGVDAYVL
                     KERSIADLMQTLHTVLEGRKEYSPELMEVVMTHPNPLTEQEIAVLKGIARGLSNQEIA
                     DQLYLSNGTIRNYVTNILSKLDAGNRTEAANIAKESGWL"
     gene            complement(661..1758)
                     /locus_tag="VQ865_002078"
     CDS             complement(661..1758)
                     /locus_tag="VQ865_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HET3136356.1"
                     /translation="MLERLKSIHYMFWISLIFMVFPILPVVTGWLSAWHLLIDILFVV
                     AYLGVLTTKSQRLSWLYWGILLTYVVGNTAFVAVNYIWFFFFLSNLLSYHFSVGGLKS
                     LHVWTFLLAQVLVVGQLLIFQRIEVEFLVYLLVILAFVDLMTFGLVRIRIVEDLKEAQ
                     VKQNAQINLLLAENERNRIGQDLHDSLGHTFAMLSVKTDLALQLFQMEAYPQVEKELK
                     EIHQISKDSMNEVRTIVENLKSRTLTSELETVKKMLEIAGIEVQVENHLDKASLTQDV
                     ESMASMILLELVTNIIKHAKASKAYLKLERTEKELILTVSDDGCGFAFLKGDELHTVR
                     DRVFPFSGEVSVISQKHPTEVQVRLPYKERN"
     gene            complement(1758..2495)
                     /locus_tag="VQ865_002079"
     CDS             complement(1758..2495)
                     /locus_tag="VQ865_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004249339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136357.1"
                     /translation="MKRWIALSKIEFLLTKRQLIYYLLSVGMPTAFYLFFSGIYQDTP
                     GELANFMRDYLISMTAFSMMSTTILSFPAVLHTDKMNNWQKTLRHSPVNMVEYYLSKI
                     TSMLVDYLVSILVVFTVGHFVRGVDMPLVKWVGAAILLIVGSIAFVALGLTLTLLPTS
                     QLMSVVGNLLYLGLAVLGGLWMPISLFPDWMQVVGKCLPTYQLMELLKTFLNEGGINL
                     SATVYLLVFSVVLFGLTIYLQGHKENA"
     gene            complement(2497..3381)
                     /locus_tag="VQ865_002080"
     CDS             complement(2497..3381)
                     /locus_tag="VQ865_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HET3136358.1"
                     /translation="MTVVKVEKLSKKIKDKEILRNISFEINDGECVALIGPNGAGKTT
                     LLDCLLGDKLVTSGQVSIQGLPVTSSKLDYTRAYLPQENVIVQKLKVKELIAFFQRIY
                     PNPLSNQEIDQLLQFVKQQKEQLAEKLSGGQKRLFSFVLTLIGRPKIVFLDEPTASMD
                     TSTRQRFWEIVQELKAQGVTILYSSHYIEEVEHTADRILLLNKGELIRDTTPLAMRSE
                     EIEKHFILPIAYKEVVEQSNLVENWTLKQDSLQVVTREADAFWELLAQAGCRMQEIEV
                     NNRSLLNTIFEETQKGDN"
     gene            complement(3368..3562)
                     /locus_tag="VQ865_002081"
     CDS             complement(3368..3562)
                     /locus_tag="VQ865_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000820182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136359.1"
                     /translation="MKRGIIYFFIGLSLLVWLVEMFTDWFDQALLCQFIRGALEFGFM
                     IFVVFPMGMEWLKGESHDGG"
     gene            complement(3559..3765)
                     /locus_tag="VQ865_002082"
     CDS             complement(3559..3765)
                     /locus_tag="VQ865_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136360.1"
                     /translation="MGEEEMRNKMIIAMSLVVAGVMTYLMFSGLDEDFYHFPWKVFAG
                     FGIMSWLVREGLKLVRDVKKEFEE"
BASE COUNT         1421 a          962 c          701 g         1263 t
ORIGIN      
        1 tattgttcca ttcactaccg tcaattttag cacatagtct tcatgaaaat attatatcat
       61 cataaccaac cagattcttt tgcgatatta gctgcctctg ttcgattacc agcatccagt
      121 tttgaaagaa tattggtgac atagtttcga atagttccgt ttgagaggta aagctgatct
      181 gcgatttctt ggttggataa gccccgggcg attcccttta aaacagcaat ctcttgttct
      241 gtcaacggat taggatgcgt catcaccact tccatcaatt caggcgaata ctctttgcgc
      301 ccttcgagga cggtgtgcaa ggtttgcatg aggtctgcaa tgcttctttc tttcaagaca
      361 taagcatcca ctccagcctt gaccgcacgt tcaaaatacc ctggacgctt gaaggtcgtc
      421 accacaacca cctttgtttc aagcctttct gatcgtatcc actccaagac ttcaagacct
      481 gtcttaacag gcatttctac gtcaaggatg gcgatatcta cagactcctt ttctaatagt
      541 tggattgctt cttgcccatt cttggcttga aggacagact ccacatctgg ttgaagcgtg
      601 agcaattgac acatggcatc tcgcaacata ctttgatctt ctgcgactaa tactttcatc
      661 ttagtttctc tccttataag gtagtcgaac ttgcacttcc gttggatgtt tctgactgat
      721 tacacttact tctcctgaaa atggaaaaac acgatctcgg actgtatgga gctcatctcc
      781 ttttagaaaa gcaaagccgc agccatcatc acttactgtt aaaatgagtt ccttctctgt
      841 ccgttctaat tttaagtaag ctttagacgc tttggcatgt ttgatgatat tggtcaccaa
      901 ctcaagcaaa atcatagaag ccattgactc cacatcctgg gtcaagctag ccttgtctaa
      961 gtgattctca acttgaacct caattccagc aatttctaac atctttttca cagtctctag
     1021 ttcggatgtc aaagttctag acttaagatt ttccacaatg gttcgcactt cattcatgga
     1081 atccttgctg atctggtgaa tttcttttaa ttccttttcc acctgtggat aagcctccat
     1141 ctgaaataac tgcaaggcta gatcagtttt aacactaagc atagcaaagg tatgccccag
     1201 actatcatgc aaatcttgac cgatacgatt gcgttcattt tcagcaagca atagatttat
     1261 ctgggcattt tgcttaacct gtgcttcttt caaatcctcc acaattcgaa tccgaaccaa
     1321 gccaaaagtc attaaatcga caaaagcaag aattacaagt agatagacta gaaactcaac
     1381 ttcgattctc tgaaaaatca acagttgacc cacaacaagg acttgagcaa gaagaaaagt
     1441 ccagacatgt aaagacttta aaccacctac gctgaaatga tagcttaaga gattggatag
     1501 gaaaaagaaa aaccagatat aattaacagc cacaaaggca gtattcccaa ctacataagt
     1561 cagcaggatg ccccaatata gccaagatag acgctggctc ttagttgtta aaacacccaa
     1621 atacgccact acaaatagaa tatcaatcaa taaatgccag gcagaaagcc acccagtcac
     1681 tacaggtagg atggggaaaa ccataaaaat taaactgatc caaaacatat aatgtatgct
     1741 tttcagtctt tcaagcatta agcattctcc ttatgacctt gaaggtaaat ggtcaaacca
     1801 aacaaaacta ctgaaaaaac aagtaaataa actgtggctg atagattgat gccaccctca
     1861 tttaagaagg tcttgagcaa ctccatcaac tgataggtcg ggagacactt acctactact
     1921 tgcatccagt ctggaaataa agaaatgggc atccagagtc cgcctaaaac agccaatcct
     1981 agataaagaa gattgcccac aacagacatc agctgactag ttggtaagag agtcaaggtc
     2041 aagccaagtg ctacaaaagc aatactcccc acaatcagca aaatcgcagc tccaacccat
     2101 tttactagag gcatgtctac acctcttaca aaatgtccaa ctgtaaaaac aaccagaatt
     2161 gagaccaaat aatcaaccag catacttgtt atctttgata gataatattc taccatattt
     2221 acagggctat gacgcaatgt tttctgccag ttgttcatct tatcggtatg taaaacagct
     2281 ggaaatgaga ggatagttgt cgacatcatg gaaaaggcag tcatggagat gaggtaatca
     2341 cgcataaaat tcgcgagttc acctggtgtg tcctgataga taccagaaaa aaataaatag
     2401 aaagccgtcg gcatccctac cgacaataga taatagatta attgtcgttt ggtcaataaa
     2461 aattctatct tactaagtgc tatccatcgt ttcatcttag ttatctccct tctgcgtctc
     2521 ttcaaagatt gtattcaaca aactacgatt attaacttcg atttcttgca tcctacatcc
     2581 tgcttgggct aatagttccc agaaagcatc tgcttctcga gtgactactt gtaaagaatc
     2641 ttgctttagg gtccagtttt caaccaaatt tgactgctct acgacttcct tgtaagctat
     2701 aggaaggata aagtgctttt ctatttcctc gctacgcata gctagaggcg tcgtatctcg
     2761 aatcaactct cccttattta agagcaaaat gcggtctgca gtgtgttcca cttcctcaat
     2821 ataatgggac gaatagagaa tggtgactcc ttgcgctttt aactcctgga caatttccca
     2881 aaaacgttga cgagttgagg tatccatgga cgcagtaggc tcatctaaaa aaacaatctt
     2941 tggtcgccca attaaggtca agacgaaaga aaagagacgc ttttgaccgc ctgataattt
     3001 ttctgccaac tgttcttttt gttgcttgac aaactgcaat agttgatcaa tttcctgatt
     3061 gctcaaagga tttggataga tacgttgaaa gaaagcaatc aactctttaa cttttaattt
     3121 ctgaacgatt acattttctt gagggaggta agccctagta tagtctaact tagaactcgt
     3181 cactggtaaa ccttgaatag atacttgacc gcttgtgacc agtttatctc caagcaaaca
     3241 atctaagagt gttgtctttc cggcaccatt tggaccaatt aaggcaacac attcaccatc
     3301 gttgatttca aaggagatgt tccgcaaaat ttccttgtct tttattttct tactcaattt
     3361 ctcaacttta accaccgtca tgagactctc ctttcaacca ctccattccc atagggaaaa
     3421 cgacgaaaat cataaatcca aactccaaag caccacgaat gaattggcaa agcaaggctt
     3481 gatcaaacca atcagtaaac atttccacta accataccaa gagtgacagg ccgataaaga
     3541 aatagatgat ccctctcttc attcttcaaa ctcctttttc acatctctga ctaatttcaa
     3601 accttctcta acaagccaag acatgattcc aaagccagca aagaccttcc aaggaaaatg
     3661 gtagaaatcc tcatccaatc ccgaaaacat gagataggtc ataactcctg ctactactaa
     3721 actcattgca ataatcattt tatttctcat ctcttcttcc cccatttcat actacaatta
     3781 tagtctttta aaatcagagg aggcagaagc ttctgtcact agaaaatatg acaaatgtca
     3841 taaaaaattc tgttcaaaac aagcaagata cattatacaa taaaacacaa tcagaaaaat
     3901 ctaaggcaac ttcctcaaaa gagatatcaa actcaattca caccataatg taaactaata
     3961 cttatttaaa atcaaaaaga gtagaaattt ttatcagaca aacacatata tagtgtattg
     4021 aatctataac agtaggcctt aaatactaaa atatttctat aaattaattt aactttcctg
     4081 atagagctgt tcatatctta tttcaattct ctatattata cgttgaacaa aacccttcta
     4141 ttgctttctt aaaaatttat aagagttata aaatctgtta aatttcaatg tgtataccta
     4201 aactacggta tttattgaaa agactggaga caaaaagtat acgctgccaa aatgaattac
     4261 tgaaaatcaa aaaagagaga accaaactga ttccctctta atgtatataa tatctagttt
     4321 taaaaataca cactcacata tctctgt
//
LOCUS       DAVBOG010000090         4193 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.091, whole genome shotgun sequence.
ACCESSION   DAVBOG010000090 DAVBOG010000000
VERSION     DAVBOG010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 4193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4193
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.091"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            720..1712
                     /locus_tag="VQ865_002083"
     CDS             720..1712
                     /locus_tag="VQ865_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018371202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HET3136361.1"
                     /translation="MAMIEVEHLQKNFVKTVKEPGLKGALRSFIHPEKQTFEAVKDLT
                     FEVPKGQILGFIGANGAGKSTTIKMLTGILKPTSGFCRINGKIPQNNRQDYVKDIGVV
                     FGQRTQLWWDLALQETYTVLKEIYDVPNSLFHKRMDFLNEVLDLKDFIKDPVRTLSLG
                     QRMRADIAASLLHNPKVLFLDEPTIGLDVSVKDNIRRAITQINKEEETTILLTTHDLS
                     DIEQLCDRIFMIDKGQEIFDGTVSQLKETFGKMKTLSFELLPGQSHLVSHYEGLSDMT
                     IDRQGNSLNIEFDSSRYQSADIIKQTLSDFEIRDLKMVDTDIEDIIRRFYRKEL"
     gene            1714..2532
                     /locus_tag="VQ865_002084"
     CDS             1714..2532
                     /locus_tag="VQ865_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000240175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-2 family transporter protein"
                     /protein_id="HET3136362.1"
                     /translation="MIKLWRRYKPFINAGVQELITYRVNFILYRIGDVMGAFVAFYLW
                     KAVFDSSQESLIQGFSMADITLYIIMSFVTNLLTRSDSSFMIGEEVKDGSIIMRLLRP
                     VHFAASYLFTELGSKWLIFISVGLPFLSVIVLMKIISGQGIVEVLGLTVLYLFSLTLA
                     YLINFFFNICFGFSAFVFKNLWGSNLLKTSIVAFMSGSLIPLAFFPKVVSDILSFLPF
                     SSLIYTPVMIIVGKYDASQILQALLLQFFWLLVMVGLSQLIWKRVQSFITIQGG"
     gene            2534..3319
                     /locus_tag="VQ865_002085"
     CDS             2534..3319
                     /locus_tag="VQ865_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003010202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HET3136363.1"
                     /translation="MKKYQRMHLIFIRQYIKQIMEYKVDFVVGVLGVFLAQGLNLLFL
                     NVIFQHIPFLEGWTFQEIAFIYGFSLIPKGMDHLFFDNLWALGQRLVRKGEFDKYLTR
                     PINPLFHILVETFQIDALGELLVGGILLGTTVTSIVWTLPKFLLFLVCIPFATLIYTS
                     LKIATASIAFWTKQSGAMIYIFYMFNDFAKYPISIYNSLLRWLISFIVPFAFTAYYPA
                     SYFLQEKDVFFNVGGLMLISLVFFVISLKLWDKGLDSYESAGS"
     gene            3358..3636
                     /locus_tag="VQ865_002086"
     CDS             3358..3636
                     /locus_tag="VQ865_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HET3136364.1"
                     /translation="MFVIEEVKDENQKKAVVAEVLKDLPEWFGIPESTQAYIEGTTTL
                     QVWTAYQESDLTGFVSLSYSSEDCAEIDCLGVKKLIKVEKLGANCLLL"
     gene            3621..3818
                     /locus_tag="VQ865_002087"
     CDS             3621..3818
                     /locus_tag="VQ865_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012512706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136365.1"
                     /translation="MLATLESEARKKVGYLQVKTVAEGSNKDYDRTNDFYRGLGFKKL
                     EIFPQLWNPQNPCQILIKKLE"
BASE COUNT         1171 a          717 c          904 g         1401 t
ORIGIN      
        1 gctatatatt atggtatcga atcttcatca gagtgataaa attaatcaat taatatctga
       61 ttacaaacag aatatgaaag ctttttatat cactattgaa aaatttatac gagatgatga
      121 aagccttaag tgttatttta taaaggttat ttcaagtcgt tccaaggtaa caagtctaga
      181 tcagattgaa gctgataaaa cgatacaaag aaaatattca agtgagctaa aaaaatttat
      241 tggattttat aatgagatta tttgtgagga aaatagtttc ctacatgtac gaaagaggtg
      301 gtcgagttgg tttaggtagt cggtgcgtga gttgataatt ctcagggtat ggacttcttt
      361 ttcatgaatg aggtaaaaga gcaggtattg tttagagaca atcattctga gcatattttc
      421 tggatagagg gagtatccga ttttatgatc aaagttaata ccgccctctg gtgagaagat
      481 gagtaggttg gtaatttaaa ctattaaaca gaatttttga ttaaaagtat tattttatga
      541 gagaaatcct aattttacaa tccataggca aacgcttgca tttcgttttt tattggacta
      601 taataggttg gtataaagcc ttttgtagta ataaaatgta gaaggtgtag aaagtaagga
      661 tttagaatat ttgtagttaa aaacacaatg ttgctattcc ttacgatagg gagatagata
      721 tggcaatgat agaagtggaa catcttcaga aaaattttgt gaagactgtt aaggaaccgg
      781 gcttgaaggg ggctttgcgc tcctttattc atcctgaaaa gcagaccttt gaagcggtca
      841 aggatttgac ctttgaggtt ccaaaagggc agattttagg atttatcggg gcaaatggtg
      901 ctgggaagtc gacaaccatt aaaatgctga caggaatttt gaaaccaaca tctggttttt
      961 gtcggattaa cggcaagatt ccccagaaca atcggcaaga ttatgtcaaa gatattggcg
     1021 tagtctttgg acaacgcacc cagctatggt gggatttggc tctgcaagag acctacactg
     1081 tcttaaaaga gatttatgat gtgccaaact cgctctttca taagcgcatg gactttttga
     1141 atgaagtctt ggatttgaag gactttatca aggatcccgt gcggactctt tcactgggac
     1201 aacggatgcg ggcggatatt gcggcctcct tgctccacaa tcccaaggtt ctttttttag
     1261 atgagccgac cattggtttg gacgtttcgg ttaaggataa tattcgtcgg gcaattactc
     1321 agatcaataa agaggaagaa actaccattc ttttgaccac tcacgatttg agtgatattg
     1381 agcaactttg tgatcggatt ttcatgattg acaaggggca agagattttt gatggaacgg
     1441 tgagccaact caaggagacc tttggtaaga tgaagactct ctcttttgaa ctgctaccag
     1501 gtcaaagtca tctcgtctct cactatgaag gtctgtctga tatgaccatt gatagacaag
     1561 gaaacagcct caacattgaa tttgatagtt ctcgctacca gtcagctgac attatcaagc
     1621 aaaccctatc tgattttgaa atccgcgatt tgaagatggt ggatacggat attgaggata
     1681 ttatccgtcg cttctaccga aaggagctct aggatgatca aattgtggag acgttataaa
     1741 ccctttatca atgcaggggt tcaggagttg attacttacc gagtcaactt tattctctat
     1801 cggattggcg atgtcatggg ggcttttgtg gccttttatc tctggaaggc tgtctttgat
     1861 tcttcgcaag agtctttgat tcagggcttc agtatggcgg atatcaccct ctacatcatc
     1921 atgagttttg tgaccaatct tctgactaga tccgattcgt cctttatgat tggggaggag
     1981 gtcaaggatg gctccattat catgcgtttg ttgcgaccag tgcattttgc ggcctcctat
     2041 cttttcaccg agcttggttc caagtggttg atttttatca gcgttggcct tccattttta
     2101 agtgtcattg tcttgatgaa aatcatatcg ggtcaaggta ttgtagaggt gctaggatta
     2161 actgtccttt atctttttag cttaacgctc gcctatctga ttaacttttt ctttaatatt
     2221 tgctttggat tttcagcctt tgtgtttaaa aatctttggg gttccaacct acttaagact
     2281 tccatagtgg cttttatgtc ggggagtttg attcccttgg cattctttcc aaaggttgtt
     2341 tcagatattc tctccttttt gcctttttca tccttgattt atactccagt tatgatcatt
     2401 gttggaaaat acgatgccag tcagattctt caggcactcc ttttgcagtt cttctggctc
     2461 ttagtgatgg tgggattgtc tcagttgatt tggaaacggg tccagtcctt tatcaccatt
     2521 caaggaggtt agtatgaaaa aatatcaacg aatgcatctg atttttatca gacaatacat
     2581 caaacaaatc atggaatata aggtggattt tgtggttggt gtcttgggag tctttctggc
     2641 tcaaggcttg aatctcttgt ttctcaatgt catctttcaa catattccat tcctagaagg
     2701 ctggaccttt caagagatag ctttcattta tggattttcc ttgattccca agggaatgga
     2761 ccatctcttt tttgacaatc tctgggcact agggcaacgc ctagtccgaa aaggagagtt
     2821 tgacaagtat ctgactcgtc ccatcaatcc tctctttcac atcctagttg aaacctttca
     2881 gattgatgcc ttgggtgaac tcttagtcgg tggtatttta ttgggaacaa cagtgaccag
     2941 cattgtttgg actcttccaa aattcctgct tttcctagtt tgtattcctt ttgcgacctt
     3001 gatttatact tctcttaaaa tcgcaacagc cagtatcgcc ttttggacta agcagtcagg
     3061 cgccatgatt tacatcttct atatgttcaa tgactttgct aagtatccga tttctattta
     3121 caattctctt cttcgttggt tgattagctt tatcgtgcct ttcgccttta cagcctacta
     3181 tccagctagc tatttcttac aggaaaagga tgtgttcttt aacgtaggag gtttgatgtt
     3241 gatttctctg gttttctttg ttatttccct taaactttgg gataagggct tagattccta
     3301 cgaaagtgcg ggttcgtaaa agctaaagta agactaaaat caagaaagaa acttatgatg
     3361 tttgtaattg aagaagtcaa ggatgaaaat caaaaaaagg cagttgtagc tgaggttttg
     3421 aaggatttgc cagaatggtt tggaatccca gaaagcacac aagcctatat agaaggaacc
     3481 acgacactgc aagtttggac cgcctatcag gagagtgatt tgactggatt tgtaagctta
     3541 tcctattcga gtgaagattg tgcagagatt gattgtctcg gcgtaaaaaa gcttatcaag
     3601 gtagaaaaat tgggagccaa ttgcttgcta ctttagagag tgaagctcgt aaaaaagttg
     3661 gttatctgca ggtcaaaaca gtagcagaag gttctaataa agattatgat cgaacaaatg
     3721 acttttatcg aggtcttggc tttaaaaagt tagagatttt tcctcaacta tggaatccgc
     3781 aaaatccttg tcagattttg attaaaaagc ttgaataata ttatttgaca tctattctca
     3841 gagtgctata ctgtaagtgt aatcgccgat ttagctcagt tggtagagca aggcactcgt
     3901 aaagcctagg ttataggtag ataaacgact gaggatttga aaaaatagat aggtagaaga
     3961 taaccgttaa gccttattct tagcggttat ttatattgtt taatagcgct gatatttcat
     4021 caattatgcc tgttttcgtg tttctggtag ttgttcaagt ttattgctac tatttttgat
     4081 ggtatgaatg tgcttataat gtatcccggt taacgaaagt tttggactta tactcttaga
     4141 aaatctcttc aaaccacgtc aacgtcgcct tgccgtgcgt atggttactg act
//
LOCUS       DAVBOG010000091         2909 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.092, whole genome shotgun sequence.
ACCESSION   DAVBOG010000091 DAVBOG010000000
VERSION     DAVBOG010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2909)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2909)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2909
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.092"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(64..1005)
                     /locus_tag="VQ865_002088"
     CDS             complement(64..1005)
                     /locus_tag="VQ865_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000806289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HET3136366.1"
                     /translation="MKQTKRIKRWRYYLRRFAYQIKILRVLQSISREKYDEKISASLV
                     YGFLSAVAVNFFFQPGHVYSSGATGLAQIISALSNHWFGFHIPISLSFYAINFPLMVL
                     AWYQIGHKFTVFTFITVSMSSFFIQFVPVATLTEDPIINALFGGVVMGLGIGFALRNN
                     ISSGGTDIVSLTIRKKTGKNVGSISFLVNGTIMLIAGLTFGWKYALYSMITIFVSSRV
                     TDAVFTKQKRMQAMIVTNHPEKVIEKIHKKLHRGATMIHDAEGTYNHERKAVLITVIT
                     RAEFNEFKQIMTQVDPSSFVSVSENVHILGRFVEIDN"
     gene            complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ865_002089"
     CDS             complement(983..2746)
                     /gene="aspS"
                     /locus_tag="VQ865_002089"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000830881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HET3136367.1"
                     /translation="MKRSMYAGRVREEHIGQEITLKGWVGRRRNLGGLIFIDLRDREG
                     IMQLVINPEKVSAEVMATAESLRSEFVIEVTGQVAAREQANDKLPTGAVELNVTALIV
                     LNTAKTTPFEIKDGIEANDDTRLRYRYLDLRRPEMLENLKLRAKVTHSIRNYLDELEF
                     IDVETPFLSKSTPEGARDYLVPSRVNKGHFYALPQSPQITKQLLMNAGFDRYYQIVKC
                     FRDEDLRGDRQPEFTQVDLETSFLTEKEIQDITEGLIARVMKETKGIEVTLPFPRMKY
                     DDAMALYGSDKPDTRFDMLLQDLTEVVKGVDFKVFSEAPAVKAIVVKGAADNYSRKDI
                     DKMTEVAKQYGAKGLAWVKVVDGELNGPVAKFLTGIQEELTTALALEDKDLVLFVADT
                     LEVVNATLGALRGRIAKELGLIDNDKFNFLWVVDWPMFEWSEEEGRYMSAHHPFTLPQ
                     EGTAHELEGDLAKVRAIAYDIVLNGYELGGGSLRINQKDLQERMFKALGFSTEEANDQ
                     FGFLLEAMDYGFPPHGGLAIGLDRFVMLLAGEENIREVIAFPKNNKATDPMTQAPSTV
                     ALKQLEELSLQVEEDETNKTN"
BASE COUNT          846 a          688 c          578 g          797 t
ORIGIN      
        1 aaccatatat acggtaaggc gacgctgacg tggtttgaag agattttcga agagtattaa
       61 tcactaatta tctatctcaa caaatcttcc tagaatatga acattttccg agacagagac
      121 aaaggagctt ggatccactt gtgtcataat ctgtttaaat tcattaaact ctgcacgtgt
      181 aatgacagtg attaaaactg cctttctctc gtgattatag gttccttctg catcatggat
      241 catggttgct ccgcggtgca attttttatg gattttttca attaccttct ctggatgatt
      301 tgtcacaatc atggcctgca tacgcttttg cttagtaaag actgcgtctg tcacacgact
      361 agagacaaag atggtaatca tagaataaag agcgtatttc caaccaaagg tcaaacctgc
      421 tatcagcatg atagttccat ttaccaagaa agaaatacta ccgacattct tacccgtttt
      481 cttgcgaata gtcaggctga cgatatccgt cccaccactg gagatattgt ttcgaagagc
      541 aaaaccaatc cccaaaccca taacaacacc cccaaaaagg gcattgataa tgggatcctc
      601 cgtcaaggtt gccacaggga caaactggat aaagaaggaa ctcatagata ccgtgataaa
      661 ggtaaagacg gtgaacttat ggccaatctg ataccaagct aagaccatca aagggaagtt
      721 aatggcgtaa aagcttagcg aaatcggaat atgaaaacca aaccagtgat tactcaaggc
      781 agagataatc tgtgccagac ctgttgcacc actcgaatac acatgccctg gttggaaaaa
      841 gaaattaact gctactgctg ataaaaaacc atagaccaga gaggccgaaa tcttctcatc
      901 atacttttct cgagagatac tttgtaagac acgtaaaatt tttatctgat aagcaaagcg
      961 gcgcagataa tagcgccacc gcttaattcg ttttgtttgt ttcatcttct tctacttgta
     1021 agctgagttc ctctagttgt ttgagagcga ctgttgatgg agcttgtgtc attgggtcag
     1081 ttgccttgtt gttcttagga aaggcaatga cttcacggat attttcttct ccagcaagca
     1141 acatgacaaa acggtcaagc ccgatagcca aaccaccgtg tggtgggaaa ccatagtcca
     1201 tggcttcaag aaggaaacca aactggtcat tggcttcttc agttgagaaa ccaagagcct
     1261 tgaacatgcg ttcttgaagg tctttttggt tgatacgaag gctaccacca ccaagctcat
     1321 aaccgttcaa gacgatatcg taagcaatgg cacgaacctt agccaaatca ccttctaatt
     1381 cgtgagcagt cccttcctgt ggaagtgtga atggatggtg ggcgctcatg tagcggcctt
     1441 cttcttcaga ccattcaaac atcggccagt caaccaccca aaggaagttg aacttatcat
     1501 tatcaatcaa gccaagctct ttagcaatac gtccacgaag ggcacccagt gttgcattaa
     1561 ccacttcaag cgtatccgcc acaaagagaa ccaagtcctt atcttcaaga gcaagcgctg
     1621 ttgtcaattc ttcttggata ccagtcaaga acttggcaac tggtccgttt aattctccat
     1681 caaccacctt gacccaagca agacctttgg caccatactg tttggctact tccgtcatct
     1741 tgtcgatgtc tttacgtgaa tagttgtccg cagctccttt gaccacaatc gcttttacag
     1801 caggtgcttc tgaaaagact ttaaagtcta cacctttgac cacttctgtc aagtcctgaa
     1861 gcaacatgtc aaaacgagta tctggcttgt cagaaccgta aagagccata gcatcatcgt
     1921 atttcatacg agggaacggt agcgttactt cgatgccttt tgtttccttc atcacgcgcg
     1981 cgatcaagcc ttctgtaata tcttggattt ctttctcagt aaggaaggac gtttccaagt
     2041 cgacctgagt aaattcaggc tggcggtctc cacgcaagtc ctcgtcacgg aaacatttaa
     2101 cgatttggta gtaacggtca aaaccagcat tcatcaagag ctgtttcgtg atttgtggac
     2161 tttgaggaag agcgtaaaaa tgccccttat taacacgaga cggcactaaa taatcacgcg
     2221 ccccttcagg cgttgactta gaaaggaatg gtgtctccac gtcgataaac tccaactcat
     2281 ccaaatagtt gcggatagag tgggtcacct tggcacgaag tttaagattt tccaacattt
     2341 ctggacgacg aaggtcaagg taacggtaac gcaaacgtgt atcgtcattt gcctcaatgc
     2401 catccttaat ctcaaatggt gttgtcttag ctgtgttaag cacaataaga gctgtcacgt
     2461 ttaactcaac cgcaccagtt ggcaacttat cattggcttg ctcacgcgca gcgacctgac
     2521 cagtcacctc aataacaaat tcgctacgaa ggctttcagc tgttgccata acctctgcag
     2581 atactttttc agggttgata accaactgca tgattccttc acggtcacga agatcgataa
     2641 agatcaaacc accaaggtta cgacgacggc caacccatcc tttcaaggtt atttcttgtc
     2701 cgatgtgttc ctcacgaaca cgaccagcat acatactacg tttcattatt tctctcctct
     2761 tttattctgt tactatttta ccataaaagc gcaggctctt catgaaaatc atcagaaaag
     2821 tttgccagtc tttaaaagtc aggtgaaagc cctaaaaatt agcgctaatg ctcttcgaaa
     2881 atctcttcaa accacgtcag cgtcgcctt
//
LOCUS       DAVBOG010000092         2853 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.093, whole genome shotgun sequence.
ACCESSION   DAVBOG010000092 DAVBOG010000000
VERSION     DAVBOG010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2853)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2853)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2853
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.093"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            108..824
                     /locus_tag="VQ865_002090"
     CDS             108..824
                     /locus_tag="VQ865_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000747760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HET3136368.1"
                     /translation="MKKRYLVVTALLALSLAACSQEKAKNEDGTAKTEQTAKADGTVG
                     SKSQGAAQKKAEVVNKGDYYSIQGKYDEIIVANKHYPLSKDYNPGENPTAKAELVKLI
                     KAMQEAGFPISDHYSGFRSYETQTKLYQDYVNQDGKAAADRYSARPGYSEHQTGLAFD
                     VIGTDGDLVTEEKAAQWLLDHAADYGFVVRYLKGKEKETGYMAEEWHLRYVGKEAKEI
                     AASGLSLEEYYGFEGGDYVD"
     gene            1133..1558
                     /gene="rplK"
                     /locus_tag="VQ865_002091"
     CDS             1133..1558
                     /gene="rplK"
                     /locus_tag="VQ865_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004226069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HET3136369.1"
                     /translation="MAKKVEKLVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGMIIPVVISVYEDKSFTFVTKTPPAAVLLKKAAGVEKGSGTPNKTKVATVTR
                     AQVQEIAETKMPDLNAANVESAMRMIEGTARSMGFTVVD"
     gene            1766..2455
                     /gene="rplA"
                     /locus_tag="VQ865_002092"
     CDS             1766..2455
                     /gene="rplA"
                     /locus_tag="VQ865_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006145049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HET3136370.1"
                     /translation="MAKKSKQLRAALEKIDSTKAYSVEEAVALAKETNFAKFDATVEV
                     AYNLNIDVKKADQQIRGAMVLPNGTGKTSRVLVFARGAKAEEAKAAGADFVGEDDLVA
                     KINDGWLDFDVVIATPDMMALVGRLGRVLGPRNLMPNPKTGTVTMDVAKAVEESKGGK
                     ITYRADRAGNVQAIIGKVSFEAEKLVENFKAFNETIQKAKPATAKGTYVTNLTITTTQ
                     GVGIKVDVNSL"
BASE COUNT          955 a          535 c          642 g          721 t
ORIGIN      
        1 attatcaatc atgaactagg attctagttt tgcaggaagt ctattaaaag attagtcaaa
       61 cgtttatcat cagaagtaga taaactatta gaaataaagg agtagaaatg aagaaaagat
      121 accttgtcgt gacagccttg ctagccttga gtctagcagc ttgttcacaa gaaaaagcaa
      181 aaaatgaaga tggcacagct aagacagaac agacagccaa agctgatggg acagtcggca
      241 gtaagtctca aggggctgcc cagaaaaaag cagaagtggt caataaaggt gattactaca
      301 gcatccaagg aaaatacgac gaaatcatcg tagccaataa acattatcct ttgtcgaaag
      361 actataatcc gggggaaaat ccaacagcca aggctgagtt ggtcaaactc atcaaagcga
      421 tgcaagaggc aggtttccct attagtgatc attacagtgg ttttagaagt tatgaaactc
      481 agaccaagct ctatcaagat tatgtcaacc aagatggaaa ggcagcagct gaccgttact
      541 ctgcccgtcc tggctatagc gaacaccaga caggcttggc ctttgatgtg attgggactg
      601 atggtgattt ggtgacagaa gaaaaagcag cccaatggct cttggatcat gcagctgatt
      661 atggctttgt tgtccgttat ctcaaaggca aggaaaagga aacaggctat atggctgagg
      721 aatggcacct gcgttatgta ggaaaagaag ctaaagaaat tgctgcaagt ggtctcagtt
      781 tggaagaata ctatggcttt gaaggcggag actacgtcga ttaatactct tcgaaaatct
      841 cttcaaacca cgtcagcgtc gccttaccta ctgactgcgt cggttctatt cacaacctca
      901 aaacagtgtt ttgagctgac ttcgtcagtt ttatctgcaa tctcaaagct gtactttgag
      961 cagcctacag ctagcttcct agtttgctct ttgattttca ttgagtataa aaaataaact
     1021 tttctcttgc aattccagat aaatagtgta taatggatgg gtatgtgaaa aacatacttg
     1081 tgggaggtaa aaatctctaa ttaccgccaa aaccacaaag gaggatttaa aaatggctaa
     1141 aaaagtcgaa aaacttgtaa aattgcaaat ccctgctggt aaagctacac cagctccacc
     1201 ggttggacct gctcttggtc aagctggtat caacatcatg ggattcacaa aagagttcaa
     1261 cgctcgtaca gctgaccaag ctggtatgat cattccagtt gttatctcag tttacgaaga
     1321 taaatcattt actttcgtta cgaaaacacc accagctgct gttcttttga aaaaagctgc
     1381 aggtgttgaa aaaggatcag gtacacctaa taaaactaaa gttgctacag ttactcgtgc
     1441 acaagtacaa gaaattgcag aaactaagat gccagatttg aacgcagcaa acgtagagtc
     1501 tgcaatgcgt atgatcgaag gtactgctcg ttctatggga ttcactgttg ttgactaatc
     1561 aataacacag tagaaaatct cacagcagtc tattagttgc ttttcatact aggcaagtga
     1621 ctgaggcttg tacttgggta cagcaaggga gcttaaggcc gtaggaagag aaaaatagta
     1681 gactgaaaac ccgcaagact tcatcatttc gagaagtgac gtgggagatg aaaatcgatt
     1741 gaaccactta caaggagaat agaaaatggc taaaaaaagc aaacaacttc gtgctgctct
     1801 tgagaaaatc gacagcacaa aagcatacag cgtagaagaa gctgtagcac ttgcaaaaga
     1861 aactaacttt gcaaaatttg acgcaactgt agaagttgct tacaacttga acatcgacgt
     1921 taaaaaagct gaccaacaaa tccgtggagc aatggtattg ccaaacggta ctggtaaaac
     1981 ttcacgtgtt cttgttttcg cacgtggtgc aaaagctgaa gaagcaaaag ctgctggtgc
     2041 agactttgtt ggtgaagatg accttgttgc taaaatcaac gacggttggt tggatttcga
     2101 cgtagttatc gctacacctg atatgatggc tcttgttgga cgtcttggac gtgtccttgg
     2161 accacgtaac ttgatgccaa accctaaaac tggtactgta acaatggatg ttgctaaagc
     2221 agttgaagag tctaaaggtg gtaaaatcac ttaccgtgct gaccgtgcag gtaacgttca
     2281 agcaatcatc ggtaaagtat catttgaagc tgaaaaattg gttgaaaact ttaaagcttt
     2341 caacgaaaca atccaaaaag caaaaccagc tacagctaaa ggaacttacg taacaaactt
     2401 gactatcaca actactcaag gtgttggtat caaagttgac gtaaactcac tttaatcagt
     2461 agttaaagta atgtaaaaaa gttgaagacg ctatgtctca actttttttg atatacgacg
     2521 ggcatgtcgt atatctgagg tgtaaatcct cggtgggcac ctactactgg tgaacccaat
     2581 agcgattccc aagtctgact atcgtgaggt agcggattaa aacggtctgg ggatagaccg
     2641 ttttaagtct gacgctggaa ataagaatcg tcagaggaag ggatagcgaa atcgtggctc
     2701 tacgaacagg aacgtgataa taaggcctat atagcggata aggtatctgg ctggggcgac
     2761 cactatcaat tatagtaaaa tgaaataaga gtaggacgaa tcgatcaggg cagccaaatc
     2821 gatttctaac aatgttttag aagaagagat gta
//
LOCUS       DAVBOG010000093         2658 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.094, whole genome shotgun sequence.
ACCESSION   DAVBOG010000093 DAVBOG010000000
VERSION     DAVBOG010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2658
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.094"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            448..2553
                     /locus_tag="VQ865_002093"
     CDS             448..2553
                     /locus_tag="VQ865_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001063457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HET3136371.1"
                     /translation="MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTSEEF
                     AHYRATGQLPGNAETDVQMPQQASGMKQDGVLAKLGRNLTAEAREGKLDPVIGRNKEI
                     QETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGL
                     EAGTQYRGSFEENVQNLVNEVKEAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKP
                     ALSRGELTVIGATTQDEYRNTILKNAALARRFNEVKVNAPSAENTFKILQGIRDLYQQ
                     HHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQHPVTDVHAVEREI
                     ETEKDKQEKAVEAEDFEAALNYKTRIAELERKIENHTEDMKVTASVNDVAESVERMTG
                     IPVSQMGASDIERLKDMAHRLQDKVIGQDKAVEAVARAIRRNRAGFDEGNRPIGSFLF
                     VGSTGVGKTELAKQLALDMFGTQDAIIRLDMSEYSDRTAVSKLIGTTAGYVGYDDNSN
                     TLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIATS
                     NAGFGYEANLTEDADKPELMDRLKPFFRPEFLNRFNAVIEFSHLTKEDLSKIVDLMLA
                     EVNQTLAKKDIDLVVSQAAKDYITEEGYDEVMGVRPLRRVVEQEIRDKVTDFHLDHLD
                     AKHLEADMEDGVLVIREKA"
BASE COUNT          850 a          480 c          614 g          714 t
ORIGIN      
        1 tcctgatcga tttgtcctgt tcttatttca ttttaatata tagttttgag atggttgata
       61 gaactgacga agtcagctca aaacatggtt ttgaggttgt agataaggag aagctgatgt
      121 ggtttgaaga ggttttcgaa gagtgtaaaa aaatattggt cagttaaagc caaaactctt
      181 gaccttttct gaccaatgta gtatattatg aacgtaaggt aaatgaaagc cttactagaa
      241 cacttattta aagtaaaata gaaagaggtg ggtctatgtt tcatctagaa atcttcagaa
      301 gtaaagatgg tctactcctg cttgaaaaag aaaaaccaga aatagtacgt agggtagcgg
      361 tttaactagt ctaaattttt taaaacaatg gtcaaagata gtcaatatca gtaatcataa
      421 ctaagtaaac aaaaagaggt aaagaatatg aataacaact ttaataattt taataacatg
      481 gatgatttat ttaaccaatt gatgggtggt atgcgaggat atagttctga aaatcgccgt
      541 tacttaatta atggacgcga agtcacatct gaggaatttg ctcactatcg tgcgactggt
      601 caattaccag gaaatgcaga aactgatgtg caaatgccac aacaggcatc aggtatgaaa
      661 caagacggtg tccttgcaaa actaggtcga aacttgacag cagaagcgcg tgagggtaag
      721 ttggatcctg ttatcggacg aaacaaggaa attcaagaaa catctgaaat cctctcacgc
      781 cgcaccaaga acaatcctgt tttggtcgga gatgcaggtg ttggtaagac agcagttgtc
      841 gaaggtctag cgcaagccat tgtgaacgga gatgttcctg ctgctatcaa gaacaaggaa
      901 attatttcta ttgatatctc aggtcttgag gctggtactc aataccgtgg tagctttgaa
      961 gaaaatgtcc aaaacttagt caatgaagtg aaagaagcag ggaatattat cctcttcttt
     1021 gatgaaattc accaaattct tggtgctggt agcactggtg gagacagtgg ttctaaagga
     1081 cttgcggata ttctcaagcc agctctctct cgtggagaat tgacagtgat tggggcaaca
     1141 actcaagacg aataccgtaa caccatcttg aagaatgctg ctcttgctcg tcgtttcaac
     1201 gaagtgaagg tcaatgctcc ttcagcagag aatactttta aaattcttca aggcattcgt
     1261 gacctctatc aacaacatca caatgtcatc ttgccagacg aagtcttgaa agcagcggtg
     1321 gattattctg ttcaatacat tcctcaacgt agcttgccag ataaggctat tgaccttgtc
     1381 gatgtaacag ctgctcactt ggcggctcaa catccagtaa cagatgtgca tgctgttgaa
     1441 cgagaaatcg aaacggaaaa agacaagcaa gaaaaagcag ttgaagcaga agattttgaa
     1501 gcagctctaa actataaaac gcgcattgca gaattggaaa ggaaaatcga aaaccacaca
     1561 gaagatatga aagtgactgc aagtgtcaac gatgtggctg aatctgtgga acgaatgaca
     1621 ggtatcccag tatcgcaaat gggagcttca gatatcgaac gtttgaaaga tatggctcat
     1681 cgcttgcaag acaaggtgat tggtcaagat aaggccgtag aagctgtagc tcgtgctatc
     1741 cgtcgtaacc gtgctggttt tgatgaagga aatcgcccaa tcggcagctt cctctttgta
     1801 gggtctactg gggttggtaa gacggagctt gctaagcaat tggcactcga tatgtttgga
     1861 acccaggatg cgattatccg tttggatatg tctgaataca gtgaccgcac agctgtttct
     1921 aagctaattg gtacaacagc aggctatgtg ggttatgatg acaatagcaa taccttaaca
     1981 gaacgtgttc gtcgcaatcc atactctatc attctcttgg atgaaattga aaaggctgac
     2041 cctcaagtta ttacccttct cctccaagtt ctagatgatg gtcgtttgac agatggtcaa
     2101 ggaaatacag taaacttcaa gaacactgtc attattgcga cctcaaatgc tggatttggc
     2161 tatgaagcca acttgacaga agatgcggat aaaccagaat tgatggaccg tttgaaaccc
     2221 ttcttccgtc cagaattcct caaccgcttt aatgcagtca tcgagttctc acacttgact
     2281 aaggaagacc tttctaagat tgtagatttg atgttggctg aagttaacca aaccttggct
     2341 aagaaagaca ttgacttggt agtcagtcaa gcggctaaag attatatcac agaagaaggt
     2401 tacgacgaag tcatgggggt tcgtcctctc cgtcgagtgg ttgaacaaga aattcgtgat
     2461 aaggtgacag acttccactt ggatcattta gatgctaaac atctggaagc agatatggaa
     2521 gatggcgttt tggttattcg tgagaaagcc taagacagaa ttttgaggat aaaaaagaag
     2581 gagccagctg aaaaaaactg gttcctttct aggtacgacg ggcatgtcgt gtagtaggtt
     2641 gaaactagaa tagtacac
//
LOCUS       DAVBOG010000094         2532 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.095, whole genome shotgun sequence.
ACCESSION   DAVBOG010000094 DAVBOG010000000
VERSION     DAVBOG010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2532)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2532)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2532
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.095"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..559
                     /locus_tag="VQ865_002094"
     CDS             <1..559
                     /locus_tag="VQ865_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3136372.1"
                     /translation="EVPCEIPESWEWVRLNDITSYIQRGKSPKYSNIPIYPVIAQKCN
                     QWSGFSIDLARFIDPETVHSYQKERLLRDGDLMWNSTGLGTLGRLAIYHENKNPYAWA
                     VADSHVTVIRVLSGVINCHFIYNFLSSPIVQSVIEEKASGSTKQKELLTKTIKEYLIP
                     LPPLPEQSRIVDKIEQFFAHIDALI"
     gene            616..1413
                     /gene="psrA"
                     /locus_tag="VQ865_002095"
     CDS             616..1413
                     /gene="psrA"
                     /locus_tag="VQ865_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000651177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type DNA invertase PsrA"
                     /protein_id="HET3136373.1"
                     /translation="MKDFELHLKKAGLAENTVRSYLYGVRFFLENYELKMEDLFEYKG
                     YLLDNFKPKTVNLRLQGVNKYLAFIGHDDLKLKFVKVQQKPFLEDVISHADYLFLKRS
                     LKKDGILKWHFVVWFLGATGARVSELIKLKVEHVEIGYFDIYSKGGKIRRLYIPKKLR
                     NSCLSWLESENRRSGYLFLNKFNEPITARGVAQQLKNYADKYKMNPKVIYPHSFRHLF
                     AKNFLAKYNDIALLADLMGHESIETTRIYLRKTATEQQNIVDKIVNW"
     gene            1424..2029
                     /locus_tag="VQ865_002096"
     CDS             1424..2029
                     /locus_tag="VQ865_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012291636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3136374.1"
                     /translation="MVKLTTCYFCDYGSYYGNIPMNWVVIKIKDIFSMNTGLSYKKGD
                     LSINNKGVRIIRGGNIKPLEFSLLDNDYYIDTQFISSEQVYLKHNQLITPVSTSLEHI
                     GKFARIDKDYDGVVAGGFIFQLTPFESSEIISKFLLFNLSSPLFYKQLKAITKLSGQA
                     LYNIPKTTLSELLIPLAPFEEQELITQKVEKLFEKVNQLWK"
     gene            complement(1977..>2532)
                     /locus_tag="VQ865_002097"
     CDS             complement(1977..>2532)
                     /locus_tag="VQ865_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001220748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3136375.1"
                     /translation="NKDETTSYPIYEIPEAWRYIKFASLVNFRIGKTPPRSEATFWGT
                     EIPWVSISDMPISGYVTNTRESISKLALKSKKIDISPKGTLLMSFKLSIGKVAILDIP
                     ATHNEAIISIFPYAKENIIRDYLMIFLPLISTLGDSKDAIKGKTLNSTSISELLIPIS
                     NHEEMKRIISKVDLLFQKVSQLFE"
BASE COUNT          863 a          363 c          439 g          867 t
ORIGIN      
        1 ggaagtacct tgtgaaatac cagaaagttg ggaatgggtg aggttaaacg atataacctc
       61 ctacattcaa agagggaagt ctccaaaata ttcaaatatt cctatatacc ctgtgattgc
      121 tcagaaatgt aatcaatggt ctggcttttc tattgactta gcaagattta ttgatcccga
      181 aacagttcat agttaccaga aagaaagatt actaagggat ggtgatttaa tgtggaattc
      241 aacaggtcta ggtacgttag gacgattagc tatttaccat gaaaataaaa atccttatgc
      301 ctgggctgtt gcagatagcc atgttacagt tataagagtc ttatcggggg ttattaattg
      361 ccatttcatc tataattttc tttcctctcc tattgttcag tcagttattg aagaaaaagc
      421 gtcgggtagt acaaaacaaa aagaattatt aacgaaaact ataaaagaat atttaatccc
      481 cctcccaccc cttcctgaac aatccagaat cgttgataaa atcgaacaat ttttcgccca
      541 tattgacgca ctaatttagt ataatagttt tacgtgcggt ggaatttcta tcaaacataa
      601 gataggagtt ttacgttgaa agattttgaa ttacatttga agaaagctgg tttagctgaa
      661 aatactgtgc gttcgtacct ttatggtgtt cgatttttct tggagaatta cgaactcaaa
      721 atggaagatt tatttgaata caaaggatat ttattagaca attttaaacc taaaactgtc
      781 aatttgcgac tacaaggagt aaataaatat ctggctttta ttggtcatga tgatttgaaa
      841 ttaaaatttg tcaaagtaca gcaaaaaccg tttttagaag atgtcattag ccatgctgat
      901 tacctttttc ttaaacgtag tttgaaaaaa gatggtattt taaaatggca ttttgtcgtt
      961 tggtttttag gtgcaactgg ggctcgtgta agtgaactta ttaaactaaa agtagagcat
     1021 gtagaaatcg gttattttga catttactca aaaggtggta aaattcgtag actgtacatt
     1081 cctaaaaaat taagaaatag ttgtcttagt tggttagaat cagaaaatcg tcgaagtggt
     1141 tatttatttt tgaataaatt taacgaacca attacagcaa gaggagttgc tcaacagtta
     1201 aaaaattatg ctgataaata caaaatgaat cctaaagtaa tttaccctca ttcttttagg
     1261 catttatttg ctaagaattt tttagcgaag tataatgata ttgccttgct tgcagatttg
     1321 atgggacacg aaagtataga aactactcga atttatctaa ggaaaacagc tactgaacaa
     1381 caaaatattg tagataaaat tgttaattgg taaaaaataa caggtggtca aactgactac
     1441 ctgctatttt tgtgattatg gctcttatta tgggaatata cctatgaatt gggttgttat
     1501 aaaaataaaa gatatttttt caatgaatac aggtctttct tacaagaagg gcgatttaag
     1561 cattaataat aaaggtgtta gaattatacg tggtggtaat attaagcctt tagaattttc
     1621 tctgttggat aatgattact acattgatac acaattcatc tcctctgaac aagtttattt
     1681 aaaacataat cagctaataa cacctgtatc aacctcttta gaacatattg gaaagtttgc
     1741 aagaatcgat aaagactatg atggtgttgt ggctggtgga tttattttcc aattaacacc
     1801 attcgaaagt tcagagatta tttcaaaatt tctattattt aacttgtctt ctccgttatt
     1861 ttataaacaa ttgaaagcaa taactaaact atcaggtcaa gctttatata atattcctaa
     1921 aactacactg agcgagctat taattccgtt agctcctttt gaggaacagg aacttattac
     1981 tcaaaaagtt gagaaacttt ttgaaaaagt aaatcaactt tggaaatgat tcttttcatc
     2041 tcttcatgat tagaaatagg gattaataat tcggagatac tggtactatt taatgttttc
     2101 cctttgatag catcttttga atcacctaaa gtagagataa gtggcaaaaa tatcattaag
     2161 taatctctga taatattttc tttagcatag gggaatatcg atataatggc ttcattatga
     2221 gtggcaggaa tatccaatat ggcaactttt ccaatagata atttaaaact cattaataaa
     2281 gttcctttag gtgaaatgtc tattttcttt gattttaatg ctaatttaga aatagattct
     2341 ctcgtattag ttacataacc agatataggc atatctgata tagataccca aggtatttca
     2401 gttccccaaa aagtagcttc actgcgtgga ggagtttttc ctattctgaa gttaactagg
     2461 ctagcaaatt taatatatct ccatgcttct gggatttcat atataggata agaggttgtt
     2521 tcgtctttgt tc
//
LOCUS       DAVBOG010000095         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.096, whole genome shotgun sequence.
ACCESSION   DAVBOG010000095 DAVBOG010000000
VERSION     DAVBOG010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.096"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(173..838)
                     /locus_tag="VQ865_002098"
     CDS             complement(173..838)
                     /locus_tag="VQ865_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HET3136376.1"
                     /translation="MSDRTIGILGLGIFGSSVLAALAKQDMNIIAIDDHAERINQFEP
                     VLARGVIGDITDEELLRSAGIDTCDTVVVATGENLESSVLAVMHCKSLGVPTVIAKVK
                     SQTAKKVLEKIGADSVISPEYEMGQSLAQTILFHNSVDVFQLDKNVSIVEMKIPQSWA
                     GQSLSKLDLRGKYNLNILGFREQENSPLDVEFGPDDLLKADTYILAVINNQYLDTLVA
                     LNS"
     gene            complement(852..2231)
                     /locus_tag="VQ865_002099"
     CDS             complement(852..2231)
                     /locus_tag="VQ865_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HET3136377.1"
                     /translation="MLFKLSKEKIELGLSRLSPARRIFLSFALVILLGSLLLSLPFVQ
                     VESSRATYFDHLFTAVSAVCVTGLSTLPVAHTYNIWGQIICLLLIQIGGLGLMTFIGV
                     FYIQSKQKLSLRSRATIQDSFSYGETRSLRKFVYSIFLTTFLVESLGAILLSFRFIPQ
                     LGWGRGLFSSIFLAISAFCNAGFDNLGSTSLFAFQTDLLVNLVIAGLIITGGLGFMVW
                     FDLAGHVGRKKKGRLHFHTKLVLLLTIGLLLFGTATTLFLEWNNAGTIGNLPVADKVL
                     VSFFQTVTMRTAGFSTIDYTQAHPVTLLIYILQMFLGGAPGGTAGGLKITTFFVLLVF
                     ARSELLGLPHANVARRTIAPRTVQKSFSVFIIFLMSFLIGLILLGITAKGNPPFIHLI
                     FETISALSTVGVTANLTPDLGKLALSVIMPLMFMGRIGPLTLFVSLADYHPEKKDMIH
                     YMKADISIG"
BASE COUNT          813 a          565 c          463 g          640 t
ORIGIN      
        1 cccgcagcta gtttcctagt ttgatctttg attttcattg agtattactc tctcttgtca
       61 cttccttcta ttttaccata aagtccagcc tttgaagaac ttttactaga agacaagggg
      121 cttctgtctc tatttgccat cttgggcatc aaaaaagagg ggtcatccct ctttacgaat
      181 tcaatgctac tagggtatcc aaatactggt tgttgatgac tgccaaaata taggtatctg
      241 ctttcaagag gtcatctggt ccaaattcaa catccaatgg ggaattttcc tgctctcgga
      301 aacccaaaat attcagattg tatttgccac ggaggtctaa tttactcaga ctttgacctg
      361 cccaagactg aggaattttc atctccacga tagacacatt tttatccaac tgaaagacat
      421 caacactatt atggaaaaga atggtctgtg ctagagactg ccccatttca tactctggcg
      481 agataaccga gtcagctcca atcttttcta gcactttctt agcggtctga cttttgacct
      541 tagcaataac agtcggtacc cccaaactct tacagtgcat aaccgcaagc acactcgact
      601 ccagattttc acctgtcgcg actacaacgg tatcgcaggt atcaatccct gctgatctca
      661 ataattcttc atctgtgatg tcaccaatca ctccacgcgc caaaactggc tcaaactgat
      721 tgatgcgctc tgcgtggtca tcaatagcga taatattcat atcctgcttg gctagggcag
      781 ctaggacact gctcccaaaa attcccaagc ccaaaattcc aatcgtacga tctgacatgc
      841 tctttccttt cttaaccaat actaatatct gctttcatat agtgaatcat atctttcttt
      901 tctggatggt aatctgccaa gctaacaaac aaggtcaagg gaccaattcg tcccataaac
      961 ataagtggca tgataacact gagagccaat ttcccaaggt caggagtcag atttgccgtt
     1021 acaccaactg tactaagagc tgaaatggtt tcaaatatga ggtggataaa gggaggattg
     1081 cctttggctg ttatccctag cagaatcaat cctatcaaga agctcatcaa aaagataata
     1141 aagacactaa aggatttttg aaccgttcgc ggcgcaatcg ttcgtctcgc aacattggca
     1201 tgaggcaagc ctagaagctc acttcgtgca aagaccaaga ggacaaaaaa tgtcgtaatc
     1261 ttgagtcccc cagctgttcc tccaggtgcc ccacctagaa acatctgtaa gatataaatc
     1321 aaaagagtca caggatgagc ctgagtataa tctatcgtag aaaagccagc tgttcgcatc
     1381 gtcactgttt gaaaaaagct aactaaaacc ttatcggcaa cagggagatt gccaatcgtt
     1441 ccagcattgt tccactcaag aaagagagta gttgccgttc caaataacaa caaacctata
     1501 gtcaacaata gtacaagctt cgtatgaaag tgcagacgtc cttttttctt tcttcctaca
     1561 tgaccagcca aatcaaacca gaccataaaa ccaaggccgc ctgtaataat caagcctgca
     1621 ataaccagat tgaccagtaa atcggtctga aaagcaaata aactggtgct ccctaaatta
     1681 tcaaaaccgg cattacagaa ggctgagatc gctagaaaaa tggaactaaa aagaccacgt
     1741 ccccagccaa gttgaggaat aaagcgaaaa ctaagcaaaa tagctcccaa gctctcaacc
     1801 aaaaaggtcg tgagaaaaat agaatagaca aactttctca aagatcgagt ttctccataa
     1861 ctaaaactat cctgaatagt tgcacggcta cgaagactaa gcttttgctt gctctggata
     1921 tagaaaaccc caataaaggt catgagccct agaccaccga tctgaatcaa gagcaaacag
     1981 attatttggc cccagatatt ataggtgtga gctactggaa gggttgagag acctgtcaca
     2041 cagactgcag agacagcagt gaaaagatga tcaaaataag tcgctcgtga gctttcaact
     2101 tggacaaagg gcaagctcaa aagaagagag cctagtaaaa tgaccaaggc aaaactcaaa
     2161 aaaatacgac gggctggcga taaacgagat aagcctagct ctattttttc cttagataat
     2221 ttgaataaca tgtttccatt gtaccataaa aagttcgaaa tgacttagat aggataaggc
     2281 aaaatctact aacaccaagc ctaaaaaatg ccaccttttt attgatagct taggcaagaa
     2341 caatacttga tagatgtgac tataggtcaa aaaagcaaga caggagcttt taacgccagc
     2401 tactctatat gcttttcagg agaaaatttc tctttttgat tataggcaat gagaaccaag
     2461 gcatcgctta gaaagctagt c
//
LOCUS       DAVBOG010000096         2481 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.097, whole genome shotgun sequence.
ACCESSION   DAVBOG010000096 DAVBOG010000000
VERSION     DAVBOG010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2481
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.097"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..88
                     /locus_tag="VQ865_002100"
     CDS             <1..88
                     /locus_tag="VQ865_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HET3136378.1"
                     /translation="MEQRMPQSPWVERIVQVLDLDYEDLFRR"
     gene            91..678
                     /locus_tag="VQ865_002101"
     CDS             91..678
                     /locus_tag="VQ865_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000821312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HET3136379.1"
                     /translation="MKRIIPVYIFQQVNVLLVSLYLLKLLCIGELTILQILYCASLIS
                     FLWMYGQRKQVVKVNMKTRMKWLGIGFVSLLIISLCFSLIHAQGTTNQANLIGLQHQV
                     PWFSFLLFLINASMVEEFLYREILWNLVRKLDIRVALTSVLFALVHHPGTILAWCLYV
                     SLGIFLGMVRYKSDLWGSMGLHLVWNLSVYVLFFL"
     gene            808..1398
                     /locus_tag="VQ865_002102"
     CDS             808..1398
                     /locus_tag="VQ865_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000227923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HET3136380.1"
                     /translation="MVDKREKLMNSFNQYGFLTFKQVIDENLHYKTLLKMVTEGKIDA
                     EEKGLYRLPDIYLDEWFVIQYRFPKGIFSLETALWLHGLSLTIPFNMTMSFPYGTNTK
                     NIKEADICPIILRSHYSEGIIEIERLPGQFIKVYEIERVLVECLRPVHQVDLQIIAPA
                     FKKYFQQNQIHLHKLFYYAQLFKVTDKLQSYTEVLS"
     gene            1398..2234
                     /locus_tag="VQ865_002103"
     CDS             1398..2234
                     /locus_tag="VQ865_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000492399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HET3136381.1"
                     /translation="MFSNANSFKAKIKNISKDKGIPAQQVQQHYLIEQVLKLISTSSY
                     RDSFIVKGGYLIGQMIGLDKRTTMDLDVTLKGTEMSRENLIDIFEEILCSKTDGFSFS
                     VDKLEPIRQDDEYGGFSLKLNATFDTLKEVVFIDITTGDKITPREITYSMTSIFTNES
                     IKIWTYNLETVLAEKLETIISRGLASTRPRDRYDLFTLYKLRKEEINLEVLKNALENT
                     AKKRKSKDTIYNWEEQVRGIEISDYQKELWIRYQRQFKYAKDISFDNSVQVIREIMQQ
                     IF"
BASE COUNT          843 a          350 c          455 g          833 t
ORIGIN      
        1 gatggaacaa cgaatgcctc aaagtccatg ggtagaaagg attgtgcagg tattagattt
       61 agattatgaa gatttatttc ggaggtaact atgaaaagaa taattccagt ttatatattc
      121 caacaagtaa atgtcttatt ggtatcccta tacttactga aattgctttg tattggtgag
      181 ttaaccatac tacagattct ctattgtgcg tcgctcattt cttttttatg gatgtatggt
      241 caacgaaaac aagtggtcaa ggtcaatatg aaaactagga tgaaatggct tggtattgga
      301 ttcgttagcc tactgattat aagcctatgt tttagtctga ttcatgctca aggaaccacg
      361 aatcaagcaa acttaattgg ccttcaacat caggttcctt ggttttcatt tttattgttc
      421 ttaatcaatg cgagtatggt tgaagaattt ctgtatcgag aaattttatg gaacttggtc
      481 agaaaattag atattcgagt tgctttgaca agtgttttat ttgccttagt acatcatcca
      541 ggaaccattc tagcttggtg tttatatgtt tcacttggga tctttttagg gatggtgcgc
      601 tataaatcgg acttatgggg aagtatgggt ctacatttgg tgtggaacct atcagtctat
      661 gtcttatttt ttctttaata atagctggtc tgtcttacgt atggattaat tttgaaataa
      721 aaaaactaaa tgaattgatt ttaaagaaat aaaatgctaa catatataga agatgttagc
      781 attttatttc taagaaagga gaatggtatg gttgataaaa gagagaaact gatgaactct
      841 ttcaatcagt atggtttttt aacttttaaa caagtaatag atgaaaattt acactacaaa
      901 accttattaa aaatggttac agaaggaaaa atcgatgctg aagaaaaagg gttatatcgc
      961 ttacctgata tttatttaga tgagtggttt gtcattcagt atcgatttcc aaaaggaatc
     1021 ttttctttgg agacagcact ttggttacat ggtttatctt tgactatccc ttttaacatg
     1081 acaatgagtt ttccttatgg tacgaatacc aaaaacatta aggaagcaga tatatgtcct
     1141 attatcttac gctctcacta tagtgaagga attattgaaa tagagcgtct tcctggtcaa
     1201 tttattaaag tttatgaaat tgaacgagtt ttggttgaat gtctaagacc agttcatcag
     1261 gtggatcttc aaattattgc accagcgttt aagaaatatt ttcaacagaa tcaaattcat
     1321 ttacacaaat tattttatta tgcccaacta tttaaagtaa ctgataagtt acaatcttat
     1381 acggaggtgc tatcttaatg ttttcaaatg cgaatagctt taaagcaaaa atcaaaaata
     1441 tttcaaaaga taagggaatt ccagctcaac aagtacaaca acattattta attgagcaag
     1501 tgttaaagct gatttctact agttcttata gagattcctt cattgtaaaa ggagggtatc
     1561 taataggtca aatgattgga ctagataagc gaaccacaat ggatttagat gtcactctga
     1621 agggaaccga aatgagcaga gaaaatttga ttgatatctt tgaagagatt ctttgttcta
     1681 aaactgatgg tttttcattt tcagtagata agctagaacc tattcgccaa gatgatgaat
     1741 atggaggatt ttcattaaaa ttaaatgcaa cttttgatac attaaaggag gttgttttta
     1801 ttgatattac tactggtgat aagatcacac caagagaaat tacttattca atgacttcta
     1861 tctttactaa tgaaagcatc aagatatgga catataatct agaaactgta cttgctgaaa
     1921 agttagaaac aatcattagt aggggattag cttcaacacg cccacgtgat cgatatgatc
     1981 ttttcacctt gtataaactt agaaaagaag agattaatct tgaagtatta aaaaatgcac
     2041 ttgaaaatac agcaaaaaaa cgtaaaagta aagatactat ttataattgg gaagaacaag
     2101 tgagaggaat tgaaatttct gattatcaga aagagctatg gattcgttat caacgccaat
     2161 ttaagtatgc taaagatatc tcatttgata actctgttca ggttattagg gaaattatgc
     2221 aacaaatatt ttagtacaaa agtaactcat tcgtaaagca gtgagttgct ttttttattc
     2281 caacaacctc aaacatgtga taaaaatttc aactactctt atctataata aagctacctg
     2341 ttctttgaaa attgaatcca ctccgtcttg attagcgtgc ctgtgtaagt agggaatgag
     2401 agtatttccc tgtgaagggc aactggcaca agacgtgtgt gagaattttc taacagacac
     2461 ggagtttatc gtttccagac t
//
LOCUS       DAVBOG010000097         2364 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.098, whole genome shotgun sequence.
ACCESSION   DAVBOG010000097 DAVBOG010000000
VERSION     DAVBOG010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2364
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.098"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..1523
                     /gene="phtA"
                     /locus_tag="VQ865_002104"
     CDS             <1..1523
                     /gene="phtA"
                     /locus_tag="VQ865_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtA"
                     /protein_id="HET3136382.1"
                     /translation="FDPAQITSRTARGVAVPHGDHYHFIPYSHMSELEERIARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPGPQPAPNLKIDSNSSLVSQLVRKVGEGYVFEEK
                     GISRYVFAKDLPSETVKNLESKLSKQESVSHTLTAKKENVAPRDQEFYDKAYNLLTEA
                     HKALFENKGRNSDFQALDKLLERLNDESTNKEKLVDDLLAFLAPITHPERLGKPNSQI
                     EYTEDEVRIAQLADKYTTSDGYIFDEHDIISDEGDAYVTPHMGHSHWIGKDSLSDKEK
                     VAAQAYTKEKGILPPSPDADVKANPTGDSAAAIYNRVKGEKRIPLVRLPYMVEHTVEV
                     KNGNLIIPHKDHYHNIKFAWFDDHTYKAPNGYTLEDLFATIKYYVEHPDERPHSNDGW
                     GNASEHVLGKKDHSEDPNKNFKADEEPVEETPAEPEVPQVETEKVEAQLKEAEVLLAK
                     VTDSSLKANATETLAGLRNNLILQIMDNNSIMAEAEKLLALLKGSNPSSVSKEKIN"
     gene            1681..>2364
                     /locus_tag="VQ865_002105"
     CDS             1681..>2364
                     /locus_tag="VQ865_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3136383.1"
                     /translation="MKINKKYLAGSVATLVLSVCAYELGLHQAQTVKENNRVSYIDGK
                     QATQKTENLTPDEVSKREGINAEQIVIKITDQGYVTSHGDHYHYYNGKVPYDAIISEE
                     LLMKDPNYQLKDEDIISEIKGGYVIKVDGKYYVYLKDAAHADNVRTKEEINRQKQEHS
                     QHREGGTPRNDGAVALARSQGRYTTDDGYIFNASDIIEDTGDAYIVPHGDHYHYIPKN
                     ELSASELAAA"
BASE COUNT          831 a          430 c          476 g          627 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa cagctagagg tgttgcagtg ccacacggag
       61 atcattacca cttcatccct tactctcaca tgtctgaatt ggaagaacga atcgctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaaggcca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccag gcccgcaacc tgcaccaaat cttaaaatag
      241 actcaaattc ttctttggtt agtcagctgg tacgaaaagt tggggaagga tatgtattcg
      301 aagaaaaggg catctctcgt tatgtctttg cgaaagattt accatctgaa actgttaaaa
      361 atcttgaaag taagttatca aaacaagaga gtgtttcaca cactttaact gctaaaaaag
      421 aaaatgttgc tcctcgtgac caagaatttt atgataaagc atataatctg ttaactgagg
      481 ctcataaagc cttgtttgaa aataagggtc gtaattctga tttccaagcc ttagacaaat
      541 tattagaacg cttgaatgat gaatcgacta ataaagaaaa attggtagat gatttattgg
      601 cattcctagc accaattacc catccagagc gacttggcaa gccaaattct caaattgagt
      661 atactgaaga cgaagttcgt attgctcaat tagctgataa gtatacaacg tcagatggtt
      721 acatttttga tgaacatgat ataatcagtg atgaaggaga tgcatatgta acgcctcata
      781 tgggccatag tcactggatt ggaaaagata gcctttctga taaggaaaaa gttgcagctc
      841 aagcctatac taaagaaaaa ggtatcctac ctccatctcc agacgcagat gttaaagcaa
      901 atccaactgg agatagtgca gcagctattt acaatcgtgt gaaaggggaa aaacgaattc
      961 cactcgttcg acttccatat atggttgagc atacagttga ggttaaaaac ggtaatttga
     1021 ttattcctca taaggatcat taccataata ttaaatttgc ttggtttgat gatcacacat
     1081 acaaagctcc aaatggctat accttggaag atttgtttgc gacgattaag tactacgtag
     1141 aacaccctga cgaacgtcca cattctaatg atggatgggg caatgccagt gagcatgtgt
     1201 taggcaagaa agaccacagt gaagatccaa ataagaactt caaagcggat gaagagccag
     1261 tagaggaaac acctgctgag ccagaagtcc ctcaagtaga gactgaaaaa gtagaagccc
     1321 aactcaaaga agcagaagtt ttgcttgcga aagtaacgga ttctagtctg aaagccaatg
     1381 caacagaaac tctagctggt ttacgaaata atttgattct tcaaattatg gataacaata
     1441 gtatcatggc agaagcagaa aaattacttg cgttgttaaa aggaagtaat ccttcatctg
     1501 taagtaagga aaaaataaac taatgaaaaa tgaaagtctc gataaagagg ctttcatttt
     1561 tattatgtat atatgtaaaa ttcttgacaa gcaatattaa aaagagtaaa ctattaacta
     1621 gttaattaac cggtttatta ctttatagtg aatcaaatat acttaagaaa agaggaaaga
     1681 atgaaaatca ataaaaaata tctagctggg tcagtagcta cacttgtttt aagtgtctgt
     1741 gcttatgaac taggtttgca tcaagctcaa actgtaaaag aaaataatcg tgtttcctat
     1801 atagatggaa aacaagcgac gcaaaaaacg gagaatttga ctcctgatga ggttagcaag
     1861 cgtgaaggaa tcaatgccga acaaatcgtc atcaaaataa cagaccaagg ctatgtcact
     1921 tcacatgggg accactatca ttattacaat ggtaaggttc cttatgacgc tatcatcagt
     1981 gaagaattgc tgatgaagga tccaaactac cagctaaagg acgaggatat tatcagtgaa
     2041 atcaagggtg gttatgtgat taaggtagat ggaaaatact atgtttacct taaggatgca
     2101 gctcatgcgg ataatgtccg tacaaaagaa gaaatcaatc gacaaaaaca agagcatagt
     2161 caacatcgtg aaggtgggac tccaagaaac gatggtgctg ttgccttggc acgttcacag
     2221 ggacgctaca ccacagatga tggttatatc tttaatgctt ctgatatcat tgaagatact
     2281 ggtgatgctt atatcgttcc tcacggcgac cattaccatt acattcctaa gaatgagtta
     2341 tcagctagcg agttagctgc tgca
//
LOCUS       DAVBOG010000098         2268 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.099, whole genome shotgun sequence.
ACCESSION   DAVBOG010000098 DAVBOG010000000
VERSION     DAVBOG010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.099"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            70..608
                     /locus_tag="VQ865_002106"
                     /pseudo
     CDS             70..608
                     /locus_tag="VQ865_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016399595.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
     gene            675..1085
                     /locus_tag="VQ865_002107"
     CDS             675..1085
                     /locus_tag="VQ865_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004262849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase family 2"
                     /protein_id="HET3136384.1"
                     /translation="MYYLPVDFYRYLIGREDQSVNEQVMIKCIDQQLKVNRLLVDQLD
                     LSQVSHPKMREYLLNHIEITTVISSTLLNRSGTAEHLAKKRQLWTYIQQKNPEVFQAI
                     RKTMLSRLTKHSVLPDRKLSNVVYQITKSVYGFN"
     gene            1201..>2268
                     /gene="pavB"
                     /locus_tag="VQ865_002108"
     CDS             1201..>2268
                     /gene="pavB"
                     /locus_tag="VQ865_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding SSURE repeat adhesin PavB"
                     /protein_id="HET3136385.1"
                     /translation="MKFNPNQRYTRWSIRRLSVGVASVVVASGFFVLVGQPSSVRADV
                     VNPTPGQVLPEETSGTKEGDLSEKPGDTVLTQAKPEGVTGNTNSLPTPTERTEVSEET
                     NSSSLDTLFEKDEEAQKNPELTDVLKETVDTADVDGTQASPAETTPEQVKGGVKENTK
                     DSIDVPAAYLEKAEGKGPFTAGVNQVIPYELFAGDGMLTRLLLKASDNAPWSDNGTAK
                     NPALPPLEGLTKGKYFYEVDLNGNTVGKQGQALIDQLRANGTQTYKATVKVYGNKDGK
                     ADLTNLVATKNVDININGLVAKETVQKAVADNVKDSIDVPAAYLEKAKGEGPFTAGVN
                     HVIPYELFAGDGMLTRLLLKAS"
BASE COUNT          687 a          441 c          508 g          632 t
ORIGIN      
        1 gacgttgacg cggtttgaag agattttcga agagtataag aaaaaatcag tcccctaaag
       61 gagcagatta tgaagttatt gtctatcgcc atttctagct ataatgcagc agcctatctt
      121 cattactgtg tggagtcgct agtgattggt ggtgagcaag ttgggatttt gattatcaat
      181 gacgggtctc aggatcagac tcagaaatcg ctgagtgttt agctagcaag tatcctaata
      241 tcgttagagc catctatcag gaaaataaag gccatggcgg tgcggtcaat cgtggcttgg
      301 cagaggcttc tgggcgctat tttaaagtag ttgacagtga tgactgggtg gatcctcgtg
      361 cctacttgaa aattcttgaa accttgcagg aacttgagag caaaggtcaa gaggtggatg
      421 tctttgtgac caattttgtc tatgaaaagg aagggcagtc tcgtaagaag agtatgagtt
      481 acgagtcagt cttgcctgtt cggcagattt ttggctggga ccaggtcgga aatttctcca
      541 aaggccagta taccatgatg cactcgctga tttatcggac agatttgttg cgtgctagcc
      601 agttctaact gcctgaacat actttttatg tcgataatct ctttgtcttt acgccccttc
      661 agcaggtcaa gaccatgtac tatctgcctg tcgatttcta tcgttatttg attgggcgtg
      721 aggaccagtc tgtcaatgag caagtgatga ttaagtgcat tgaccagcaa ctcaaggtca
      781 atcgactctt ggtagaccaa cttgatttgt cccaagtgag tcatcccaaa atgcgagaat
      841 atctgctgaa tcatattgaa atcacgacgg tgatttccag taccctgctc aaccgatctg
      901 gaacagcgga gcatctggca aaaaaacgcc aattgtggac ctatattcag cagaaaaatc
      961 cagaagtctt tcaggctatt cgtaagacca tgttgagccg tttgaccaaa cattctgtct
     1021 tgccagatcg caaactgtcc aatgtcgtct atcaaatcac caaatctgtt tatggattta
     1081 attaatataa gtgttttata agagggattt aagaaaaatt ttaacttttt cttagtcctt
     1141 tttaatttca ggagattata ctagagtcat caaataaaga aagactctaa ggagaatcct
     1201 atgaaattca atccaaatca aagatatact cgttggtcta ttcgccgtct cagtgtcggt
     1261 gttgcctcag ttgttgtggc tagtggcttc tttgtcctag ttggtcagcc aagttctgta
     1321 cgtgccgatg tggtcaatcc gaccccaggt caagtcttac ctgaagagac atcgggaacg
     1381 aaagagggtg acttatcaga aaaaccagga gacaccgttc tcactcaagc gaaacctgag
     1441 ggcgttactg gaaatacgaa ttcacttccg acacctacag aaagaactga agtgagcgag
     1501 gaaacaaact cttctagtct ggatacactt tttgaaaaag atgaagaagc tcaaaaaaat
     1561 ccagagctaa cagatgtctt aaaagaaact gtagatacag ctgatgtgga tgggacacaa
     1621 gcaagtccag cagaaactac tcctgaacaa gtaaaaggtg gagtgaaaga aaatacaaaa
     1681 gacagcatcg atgttcctgc tgcttatctt gaaaaagctg aagggaaagg tcctttcact
     1741 gccggtgtaa accaagtaat tccttatgaa ctattcgctg gtgatggtat gttaactcgt
     1801 ctattactaa aagcttcgga taatgctcct tggtctgaca atggtactgc taaaaatcct
     1861 gctttacctc ctcttgaagg attaacaaaa gggaaatact tctatgaagt agacttaaat
     1921 ggcaatactg ttggtaaaca aggtcaagct ttaattgatc aacttcgcgc taatggtact
     1981 caaacttata aagctactgt taaagtttac ggaaataaag acggtaaagc tgacttgact
     2041 aatctagttg ctactaaaaa tgtagacatc aacatcaatg gattagttgc taaagaaaca
     2101 gttcaaaaag ccgttgcaga taacgttaag gacagtatcg atgttccagc agcctaccta
     2161 gaaaaggcca agggtgaagg tccattcaca gcaggtgtca accatgtgat tccatatgaa
     2221 ctcttcgcag gtgatggtat gttgactcgt ctcttgctca aggcatct
//
LOCUS       DAVBOG010000099         2185 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.100, whole genome shotgun sequence.
ACCESSION   DAVBOG010000099 DAVBOG010000000
VERSION     DAVBOG010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 2185)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2185)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2185
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.100"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(400..780)
                     /locus_tag="VQ865_002109"
                     /pseudo
     CDS             complement(400..780)
                     /locus_tag="VQ865_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000443785.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
     gene            complement(1202..>2185)
                     /gene="phtB"
                     /locus_tag="VQ865_002110"
     CDS             complement(1202..>2185)
                     /gene="phtB"
                     /locus_tag="VQ865_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pneumococcal histidine triad protein PhtB"
                     /protein_id="HET3136386.1"
                     /translation="PIRHPERLGKPNAQITYTDDEIQVAKLAGKYTTEDGYIFDPRDI
                     TSDEGDAYVTPHMTHSHWIKKDSLSEAERAAAQAYAKEKGLTPPSTDHQDSGNTEAKG
                     AEAIYNRVKAAKKVPLDRMPYNLQYTVEVKNGSLIIPHYDHYHNIKFEWFDEGLYEAP
                     KGYSLEDLLATVKYYVEHPNERPHSDNGFGNASDHVQRNKNGQADTNQTEKPNEEKPQ
                     TEKPEEETPREEKPQSEKPESPKPTEEPEEESPEESPEESEEPQVETEKVKEKLREAE
                     DLLGKIQNPIIKSNAKETLTGLKNNLLFGTQDNNTIMAEAEKLLALLKESK"
BASE COUNT          619 a          451 c          353 g          762 t
ORIGIN      
        1 caattaacta atttaatcac ttaaaaaaat tcgaacactt tctatacaac tgacagctca
       61 aatctttcag aatagaacaa tactaactat cgagcacccc gtattcataa atatatgtgt
      121 aattctagac ctagaattcc tataaactaa atgctttcat actcttccaa gtaattgatt
      181 gccttaaatt ttaatttttg aaggtttcta aagctagaat agccccatca caatcagttt
      241 tgattgattc acaatttaga aacactatag tttcactcct gttaaaataa aaaggaactg
      301 cataaagcaa tccctttctg attttgaaat catttactta acattttata gttgagataa
      361 tcaatagctt acctataaaa agagttatag taaaattcct tatttattga tttcaagctc
      421 cgctaactgt gtttgaataa ctgacagttc tgcaccagcc tgaagaagag cagctgcatt
      481 ataggcacct tctacaattg gaaccctgtt gatgatgata cttttatcac tgaaatcagt
      541 caccattttt aagttcattt tagcaaaacc taggtcaaaa aaggcaagta aagtatctgc
      601 tgtattttcg gaaacaaccc tatctactta atcaaaactc gttccaattc ctccgccctc
      661 ggttcctcct acataagtaa tcggaacatc tttagctact ttactaatca gttcaacaac
      721 accttctaca atgtatttgg aatgtgaaac gataacaaga ccaataccaa tactttccat
      781 caaaccaccc cagtttctaa aatagcagta aagagtaatc ctgatgagaa tgatccagga
      841 tcaatatgtc caagaaacca catgctccta agacaagagc taacagactg gccatcaata
      901 atagtattgt tctttttttc atcattactc cttaactagt gtttaactga tcaattagcc
      961 agtaaatagt ttatctttat ttacactatc tgttaagata tagtaaaatg aaataagaac
     1021 aggacagtca aatcgatttc taacaatgtt ttagaagtag aggtatacta ttctagtttc
     1081 aatctactat attttgcaca ttttcatgaa aaaaatgaga actagaactc acattctgct
     1141 ctcatttttc gttttcccgt tctcctatcc tgtttttagg agttagaaaa tgctgctacc
     1201 tttacttact ctcctttaat aaagccaata gtttttcagc ttctgccata atagtattgt
     1261 tgtcctgggt gccaaatagt aaattatttt ttaatcctgt gagagtctct ttggcattgg
     1321 acttgataat tggattctgg atttttccaa gtaaatcttc agcctctctc agtttttctt
     1381 taaccttttc agtctcgacc tgaggttctt ctgattcctc tggtgattct tctggtgatt
     1441 cttcttctgg ttcctctgtt ggttttggag actctggttt ctcgctttgc ggtttctctt
     1501 ctcgaggggt ttcttcctca ggtttttctg tctgaggttt ctcctcgttt ggtttttccg
     1561 tttgattggt atcagcttga ccatttttgt ttctttgaac atggtcgcta gcgttaccaa
     1621 aaccattatc tgaatgcgga cgttcgtttg gatgttcgac atagtacttg acagtcgcca
     1681 aaagatcctc aagactatac cccttaggtg cctcataaag gccttcgtca aaccactcaa
     1741 atttgatgtt atggtaatgg tcataatgag gtatgattaa actaccgttt ttgacttcta
     1801 cagtatattg aagattgtaa ggcatacgat caagtggcac cttcttagct gctttcacgc
     1861 ggttgtagat agcttctgct ccttttgcct cagtatttcc tgaatcctga tggtctgtcg
     1921 aaggaggggt caaacctttc tctttagcat aagcctgggc tgccgctctc tcagcttcag
     1981 acaaactatc ttttttaatc cagtggctat gggtcatatg tggagttaca taggcatccc
     2041 cctcatcact ggttatatca cgaggatcaa agatataacc gtcttctgtt gtgtacttgc
     2101 ctgccaactt ggctacttga atctcatcat cagtgtaggt aatttgcgca tttggttttc
     2161 ctaaacgttc tggatgacga atcgg
//
LOCUS       DAVBOG010000100         1863 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.101, whole genome shotgun sequence.
ACCESSION   DAVBOG010000100 DAVBOG010000000
VERSION     DAVBOG010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.101"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..917)
                     /locus_tag="VQ865_002111"
     CDS             complement(<1..917)
                     /locus_tag="VQ865_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001155321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HET3136387.1"
                     /translation="MQDNYTTKGKHLTIDSRRLIERWKKEGKSNREVASLLGKAPQTI
                     HTEIKRGTVRQCLGKGRFKEVYSADYAQQSYENNRKRSVKKSSLTKELKEKILHYHNQ
                     KFSPEMMVMAKGVNVGISTIYYWIHHGKLGLSKQDLPYPRKGKALKKQASTNFKPAGQ
                     SIAQRPEAINLRLENGHYEIDTVLLTRAKNYCLLVLTDRKSRHQIIRLIPNKSAEVVN
                     QALKLILKQHKILSITADNGTEFNRLSDVFSEEHIYYAHPYASWERGTNENHNRFIRR
                     WLPKGTKKMTPKEVAFIEKWINNYPKKCL"
     gene            complement(1362..1760)
                     /locus_tag="VQ865_002112"
     CDS             complement(1362..1760)
                     /locus_tag="VQ865_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HET3136388.1"
                     /translation="MENKESHKSQEIGNLIRVYNRSKREEAESEPLNLYVEDEKGNLL
                     AGLIAETFGNWLEIEYLFVKEELRGQGIGSKLLQQAESEAKNRNCCFAFVNTYQFQAP
                     DFYQKHGYKEVFSLQDYLYIRQRYYYQKNL"
BASE COUNT          502 a          380 c          325 g          656 t
ORIGIN      
        1 tccaagcatt ttttaggata gttgttaatc cacttttcga tgaatgcgac ttctttggga
       61 gtcattttct tggttccctt aggtaaccat ctacgaatga acctgttgtg attctcatta
      121 gttccccttt cccaagaggc ataggggtgc gcataataaa tgtgctcctc agaaaataca
      181 tcagacaagc gattgaattc cgttccatta tctgccgtga tggaaagaat cttgtgttgt
      241 tttaagatga gttttagagc ctgattgacc acctcagcac ttttatttgg aatcaatcgg
      301 atgatctgat gtctactctt tcgatccgtc aagacaagca agcagtagtt tttcgctctc
      361 gtaagtagaa ccgtatcaat ctcataatgc ccattctcca agcgaagatt gatagcttca
      421 ggccgctgtg cgatggattg accagcaggt ttaaagttgg tgctggcctg tttcttaagc
      481 gcttttcctt ttctagggta aggcaaatcc tgcttgctta accccaattt tccatgatga
      541 atccaatagt aaatggttga aattcccacg ttaacccctt tagccatcac catcatttca
      601 ggcgaaaatt tttggttatg atagtggaga atcttttcct ttagttcctt ggtcaagctt
      661 gatttcttga ccgagcgctt gcgattgttt tcataagact gttgagcgta gtcggcagaa
      721 taaacctctt tgaagcgccc ttttccaaga cattgtcgga ctgtcccacg cttgatttca
      781 gtgtggatag tttgaggagc ttttccaagt agagaggcaa cttctctatt tgattttcct
      841 tcttttttcc atctttcgat taagcgacgg ctatcgattg tcaaatgttt accttttgta
      901 gtataattgt cttgcatttc tgtgcctttc ttgtgtttgt ggttgaacaa caagtataac
      961 acagaggtgt tttcttatgc ctacaagagc tttcattatt tccattttct tttggatttc
     1021 actctattct gaaaaacttg tgtatattta ctgaagctag caagtcttac ctgtaaattt
     1081 aatgaaagca acacaaaatc cgagagggga atctcggatt aatagataga gagtttttag
     1141 tttaaataaa ttgtttaaaa tatcaacaac atcacttctt ttcttaacct gataagtctt
     1201 gattcctaat tttggggcta cgattatatt gtcctcaata tcgtctagaa agacacaatt
     1261 tctaggttat aactggtatt tatcgatagt tactcatata catcagtcca cctccatact
     1321 tatgtgcgag cctctctttg tattatacct ccatactcac cttacagatt cttttggtaa
     1381 taatatcttt gcctaatgta gagatagtct tgcaaagaaa aaacttcctt gtagccatgt
     1441 ttctgataaa agtccggtgc ctggaactgg taagtattga caaaggcaaa acaacaattt
     1501 cgattcttag cttcactttc tgcctgttgc aatagttttg aaccgattcc ttgccctcgc
     1561 agttcctctt ttacaaacaa atactcgatt tctagccaat ttccaaaagt ctctgctatc
     1621 aaacctgcca ggagattgcc cttttcatct tcgacataaa gattaagtgg ctcactttca
     1681 gcctcttctc tttttgaacg gttataaaca cgaatcagat tccctatttc ttgcgattta
     1741 tgtgattcct tattttccaa tctaatgaaa tgaaataaaa catgcgcaaa tcgattaagg
     1801 aatttaatct aatttctaac aatgtcttag aaatcaaagt gtactatttt aacttcaatg
     1861 cac
//
LOCUS       DAVBOG010000101         1860 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.102, whole genome shotgun sequence.
ACCESSION   DAVBOG010000101 DAVBOG010000000
VERSION     DAVBOG010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.102"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(3..968)
                     /locus_tag="VQ865_002113"
     CDS             complement(3..968)
                     /locus_tag="VQ865_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3136389.1"
                     /translation="MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNN
                     NLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKD
                     CSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDN
                     CENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKI
                     HLRNYLNDRKDSHPALFVTLVGKAQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLA
                     TKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS"
     gene            complement(1086..1499)
                     /locus_tag="VQ865_002114"
     CDS             complement(1086..1499)
                     /locus_tag="VQ865_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000158364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HET3136390.1"
                     /translation="MTIYLTEKQIEKINALAIQRYSPNEKIQTVSSSALNMIVNLPEQ
                     FVFGKSLYPTIFDKATILFVQLIKKHVFANANKRTAFFVLVKFLQLNGYRFSVTVEEA
                     VKMCVTIAVEALTDEKMTSYSKWVSEHSVREKVKK"
     gene            complement(1496..1732)
                     /locus_tag="VQ865_002115"
     CDS             complement(1496..1732)
                     /locus_tag="VQ865_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000260605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HET3136391.1"
                     /translation="MVVKTRKQGNSITITIPSEFNIPSGVKYEAKLLPSGEIIFTPEE
                     LGQQVSYVSDDAFDLNLDKIFDEYDDVFKALVEK"
BASE COUNT          541 a          363 c          276 g          680 t
ORIGIN      
        1 ttttaagaga tgaatttttg gtgtgaatgc ttgacattat tttgattgac catggcatag
       61 gccagggttg tgtcaatctt gctatgacct agcagttttt ggacttgttc gataggcata
      121 cctttatcaa ttgccttagt cgctaaagtt cttctgaact tatgtgggtg aaccttttgt
      181 atgccgagtt tgtctcctaa ctttcttaag cgaatctcta caccagcaat tccaagtctc
      241 tgggcttttc caactagcgt tacaaaaaga gcagggtgac tatcttttct gtcgttaaga
      301 taatttctta aatgaatttt cgtccgagcg tcaaaatata ctggtctctc cttctttcct
      361 ttaccaaaga caacacactc tctgttttca aaatcaatat ctgaacgatt caactgtaca
      421 agctccccta cacgcatacc tgtcgatgct agtaggtcta ttattgccaa atctctcaaa
      481 ttttcacagt tatcacgcat aatttccaaa tgttcatcag tataagtttc cttcacattt
      541 tgctcagtct taattttctt tatccgtcga atgggatttt taatgatata ttcctcttgc
      601 tcaagccaag caaaaaaaga agacaatata cgcctaatat tgtctaaatt tgccttacta
      661 caatcctttt cagactggta atttgctaaa taactcctta aatcatctgt tgtgagttgt
      721 gtcacagact ctttaatagc attaaacaag ttttcaatcg tcctctggta ataacgaatt
      781 gtttttgagc tacagccctc tacctgcttg gcggtaataa atagttgcaa caggttatta
      841 ttcgaatact tctgctgctt ttttccgtct actagatgat gttctaaact ctctctcaac
      901 gctagtaatt gttcattatt taaaagaggt aacatttctt gcatgataat tgtaactttt
      961 gattccataa tttctcactt tcttattcat caataaaaag agacaatatc agtttctgca
     1021 ttacagaatt ctaatattgt ctgttcattt attttcttgt gctcattcaa atccagcata
     1081 ctaggttact ttttgacctt ttctctaaca gaatgttcag aaacccattt ggagtagctt
     1141 gtcatttttt catcagttaa agcttctact gcgatggtta cacacatttt tactgcttct
     1201 tctaccgtta cagaaaaacg atagccgttt aattgtaaaa atttgaccaa aacgaagaaa
     1261 gcagttcttt tattagcatt agcaaaaaca tgcttcttta tcaattggac aaatagtatc
     1321 gttgctttat caaaaattgt tggataaaga gacttcccaa agacaaattg ttctggtaag
     1381 ttcacaatca tatttaaggc agaagaacta actgtttgaa ttttctcatt tggagaatac
     1441 cgttgaattg ctaaagcatt tattttttca atttgctttt ctgtcagata gattgtcatt
     1501 tttccaccaa agctttgaaa acatcgtcgt attcgtcaaa tattttatct aaatttaagt
     1561 caaaggcatc atcagataca taagaaacct gctgccccaa ttcttcagga gtaaagataa
     1621 tctcaccact tggtaacaat ttcgcttcgt atttaacacc acttggaata ttaaattcac
     1681 ttggaatcgt aatggtgatt gaatttcctt gttttcttgt ttttactacc atctgatttc
     1741 ctcctttgaa gtattataac aaatcattac cgtaattaca atggcagaat atcagccaaa
     1801 atactcctgc atcagagatt tcttcaaagt ttcaagttct tccagagatt tttggattgc
//
LOCUS       DAVBOG010000102         1801 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.103, whole genome shotgun sequence.
ACCESSION   DAVBOG010000102 DAVBOG010000000
VERSION     DAVBOG010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1801)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1801)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1801
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.103"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(101..642)
                     /locus_tag="VQ865_002116"
                     /pseudo
     CDS             complement(101..642)
                     /locus_tag="VQ865_002116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007897432.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus and C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(718..1494)
                     /locus_tag="VQ865_002117"
                     /pseudo
     CDS             complement(718..1494)
                     /locus_tag="VQ865_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457791.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(1418..1612)
                     /locus_tag="VQ865_002118"
     CDS             complement(1418..1612)
                     /locus_tag="VQ865_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000691852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HET3136392.1"
                     /translation="MKIIQQQSATIDSLTNELALLREQVAYLTQKLYGKSSEKSVCPS
                     GQLSLFEEEQNMEEDSDLPS"
BASE COUNT          509 a          380 c          331 g          581 t
ORIGIN      
        1 tggattgaaa taagatatga acaaatcgat taggaaagga aaattgattt atagaaatat
       61 tttagcagtc gatgcgtact gttatagatt caacgcacta taattgatga cgtttagctg
      121 tttccaacaa actcataata atagctcttg ctttagctcc ttcaaaactt tgagaaaata
      181 accaccctcg cttttttaaa ctgagctcag gctaaaagag tccactggac tcttttactc
      241 cgtcccataa ccaatgattt aatggcgcgt tcagctagat tattggaaag gaccagatgt
      301 ccgtctttta aaatggtctt aaaggtttct ttatacttga ggctgtattc aattgccctt
      361 cctagttttg aacctgctaa aactgactga cggcggcacc aagcaaagaa gtcttccatt
      421 aggggctgga cgtttctgta gtcgttcatc agctggcaaa gcctcccagt ctctttccaa
      481 ggcaaataac tggtcacgat aggctaaacc tttagctcct aaggatgatt tatctgcttg
      541 cttgggggtc gcttcaaaaa atttccttct cacatgcgcc caacatccaa caagttcagc
      601 ttcttccagt tgacgataag cttctagcgg ttcgcagttt accaagctta gcgtcgcctt
      661 gctcctaaac cttagactgc tatcgcatag gcagaactag aggactaaag ttctaagtta
      721 ctgccgcaac atatcacaat gcatatagcc agaataattt cctaggaatt cttgcactac
      781 cgaaccactc cgacgctgat catggtggta cagcgtaatc ccttgtttct cagctttccc
      841 agacaaaaaa gtccaatagt aagtcagctg actatcactt tctaagaccc gataagaggt
      901 ttcatctgca tgaagaagag cttgttctaa caacttttct cgtaaaaggt tataaaggga
      961 ctctaaatag tattgactcg ccttgatatg ccaattagca atttccttac gtgtgattgg
     1021 taaacccatc ttagcccaat cttcttctta gcgataattg ggtaccttca gaataaactt
     1081 ctgatggatg gtgtgagcga taatagaagc tgagccaagg ctatgcgcca aaggggcttt
     1141 aggaatagga gctttcacga ttttatcact tggattattc ttactgcatg tttggcattt
     1201 gtaagcgtgt tggatatgat tcactctttt taattgcgca agaataaaga ccaattcttg
     1261 tcgttgaagg ctcgctccaa tctcttttag ctctccctga cagtcagggc aaatgcagtt
     1321 ctctaagcga tgatgaactt cttctgaatc aaattgggca agaatagctt gacgtttccc
     1381 tttagctttc ttacgtttat aggtgatttc ttctctttca actgggtaag tcagagtctt
     1441 cttccatatt ttgttcctct tcaaaaagac tgagttgtcc agatgggcaa acacttttct
     1501 cagaggattt tccatagagc ttttgcgtta gataagccac ttgttcacga agaagggcaa
     1561 gttcattggt gagactatca attgtagcac tctgttgttg aatgattttc aatcttctcc
     1621 catagacttt cctccttatt tcctaacttt attatatagt gtattgaatc tataacagta
     1681 caccttgact gctaaaatat ttctataaat taatttgact ttcctgatag agatgttcat
     1741 atcttatttc aattcactat actaaaaaga aagtcctcat ttcaatagaa atcacgactt
     1801 t
//
LOCUS       DAVBOG010000103         1646 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.104, whole genome shotgun sequence.
ACCESSION   DAVBOG010000103 DAVBOG010000000
VERSION     DAVBOG010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1646)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1646)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1646
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.104"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(242..1006)
                     /locus_tag="VQ865_002119"
     CDS             complement(242..1006)
                     /locus_tag="VQ865_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001862814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside phosphorylase"
                     /protein_id="HET3136393.1"
                     /translation="MIQKHAIPILEFDDNPQAVIMPNHEGLDLQLPKKCVYAFLGEEI
                     DRYAREVGANCVGEFVSATKTYPVYVVNYKDEEICLVQAPVGSAPAAQFMDWLIGYGV
                     EQIISTGTCGVLADIEENAFLVPVRALRDEGASYHYVAPSRYMEMQPEAIAAIERVLD
                     DRGIPYEEVMTWSTDGFYRETAEKVAYRKEEDCAVVEMECSALAAVAQLRGVLWGELL
                     FTADSLADLNQYDSRDWGSEAFNKALELSLASVHHL"
     gene            1228..1524
                     /locus_tag="VQ865_002120"
     CDS             1228..1524
                     /locus_tag="VQ865_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000450185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HET3136394.1"
                     /translation="METSISMADFYGKYQNENLELIDVREAHEFQAGHAPDAKNLPLS
                     TLEQGYKELKPDHEYYVICQGGVRSASTCQFLSSQGLTVTNVEGGMNAWPGQVE"
BASE COUNT          523 a          404 c          315 g          404 t
ORIGIN      
        1 gaagctgacc tggtttgaag agattttcga agagtatcat ttcatctcac tctaaatctt
       61 accaacataa aacgcatagt atcaaagttt tcatcacctg atatgatacg tttttctgat
      121 tttaaagatt tttcccaacc tcaacatgcc taggacaaga ggaaggtaac ctcgtttaaa
      181 catatttttg aaaagtatga gctaggcatt ttatgataaa acaaatcctt tgccagtaca
      241 actaaaggtg gtgaacactt gctaaactca gttctagcgc cttattaaaa gcttccgagc
      301 cccagtcacg actgtcgtac tggttcaagt ccgctagaga atctgctgtg aacaacaatt
      361 caccccagag aaccccacgc aattgagcta ctgccgcaag agcagaacac tccatctcca
      421 caacagcaca gtcttcttcc ttgcgataag ccaccttttc agccgtttct cggtaaaaac
      481 catctgtgga ccaggtcatg acttcttcat aaggaatccc tctatcatcc aaaactcgct
      541 caatggcagc aatagcctct ggctgcattt ccatataacg agaaggtgcc acatagtggt
      601 aactggctcc ttcatctcgc agagcgcgaa cagggactag aaaggcattt tcctctatat
      661 cagctaggac accacaggtc ccagtagaga taatctgctc cacaccatag ccaatcaacc
      721 aatccataaa ctgggctgct ggagctgaac cgacaggagc ctgaaccaga caaatctcct
      781 cgtccttgta gttcacgaca taaactggat aggtcttggt ggcagaaaca aattcgccaa
      841 cacagttcgc ccctacttcc ctcgcatagc ggtcaatctc ctcacctaaa aaagcataga
      901 cacacttctt tggcaactgc aaatccaacc cctcgtgatt gggcatgata accgcctgag
      961 gattatcatc aaactctaaa ataggaatcg catgtttctg aatcatagcc cacctcctct
     1021 aattttgtac tattgtatca aaatctgaca aagtgtcaag gaggaagctg ataaactgag
     1081 gagaaaaaca agcctacatc gtcagctgcc acagtggttt gcgcagctat atcgcagagc
     1141 ctatcctcaa gcaagcagga tttaccgtcc aaaaccttga cggcgcttat tcactataca
     1201 aaatgactaa cccagaagga gtagaatatg gaaactagta tcagcatggc tgacttttat
     1261 ggaaaatatc aaaatgaaaa tctagaactt atcgatgtcc gtgaagcaca tgaattccaa
     1321 gcaggacatg caccagatgc caaaaatctt ccattaagta ccttagagca aggctacaaa
     1381 gaactcaaac ctgaccatga atactatgtt atttgtcaag gaggagtccg ctctgcatct
     1441 acctgccaat ttctcagctc ccaaggcctc accgttacca acgtagaagg tggtatgaat
     1501 gcttggcccg gtcaagtaga ataatcaaga ggagctgggc aaaaactcaa tttcaggaga
     1561 agatgaagta atactcaatg aaaattaaag tgcaaactag gaagttagcc gcaggctgct
     1621 caaaacactg ttttaaggtt gtggat
//
LOCUS       DAVBOG010000104         1409 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.105, whole genome shotgun sequence.
ACCESSION   DAVBOG010000104 DAVBOG010000000
VERSION     DAVBOG010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1409
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.105"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            283..1293
                     /gene="ccpA"
                     /locus_tag="VQ865_002121"
     CDS             283..1293
                     /gene="ccpA"
                     /locus_tag="VQ865_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000990602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HET3136395.1"
                     /translation="MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEV
                     IDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFSSLAKGIDDIAEMYKYNIVLANS
                     DEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
                     VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGL
                     VFESKYSYDDGYALAERLISSNATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSD
                     DSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREVLLPHGLTERSSTRK
                     RK"
BASE COUNT          440 a          232 c          318 g          419 t
ORIGIN      
        1 tcctgttctt atttcatttt actataactt taggagggct tagtttcctc ctttttgttt
       61 agtctaaggt ggtagcaagg agctaaacct aggttttcta tgaaattttt tcaatcaatc
      121 ttcaaaaaac acttgaaagt gtttacaatt agtgatagaa tggaataagt agaaatatga
      181 aaacgaaatt ttcacatctt cacttttgta agtagatata gagcttcaat cagcacctct
      241 acttgtaaaa gaatatgtga gatagaaagg acaggaaaag gaatgaatgc agatgataca
      301 gtaaccattt atgatgtcgc tcgtgaagca ggtgtttcca tggcgacggt cagccgtgtg
      361 gtcaatggca ataaaaatgt aaaagagaat acccgtaaaa aagtgctaga ggtaattgat
      421 cgtttggatt atcgtccaaa tgcagttgcg cgtggtcttg caagtaaaaa gacaaccact
      481 gtcggtgtcg tgattccaaa tattaccaat ggttattttt cgagtttggc taaggggatt
      541 gatgatattg cagaaatgta caagtacaat attgtcctag ctaatagcga tgaagataac
      601 gagaaagaag tttctgttgt caataccctc ttttcaaagc aggtagatgg cattatctat
      661 atgggttatc acttgacaga taaaattcgc tcagaatttt cgcgctcacg tactccgatt
      721 gttctcgcag gaactgtcga tgttgagcac cagttgccaa gtgtcaatat tgactataag
      781 caagcaacaa ttgatgcagt gagttacctt gctaaagaaa atgagcgtat tgctttcgtt
      841 agcggtccgc tagtggatga catcaatggt aaggttcgtt tagttggcta caaggaaacc
      901 ttgaaaaaag caggaatcac ttatagtgag ggtttggtat ttgaatctaa atatagctat
      961 gatgatggtt acgccttagc agagcgtttg atttcatcaa atgcaactgc agcagttgtg
     1021 acaggtgatg agttggcagc aggagtcttg aacggtttgg ctgataaagg tgtttctgtg
     1081 ccagaagatt ttgaaattat tactagtgat gattcacaaa tctcacgctt tacccgtcca
     1141 aacttgacaa cgattgccca acctctttat gaccttggtg ctattagtat gcgtatgttg
     1201 accaagatta tgcataagga agagttggaa gaacgtgaag ttctcttacc tcatggtttg
     1261 acagaacgta gctcaacacg aaaacgtaaa tagaaaaaat cagggaatcg agaagatttc
     1321 ctgattttgt gctcttaaac aagagatgtt gacttaatga ataccataga gcggactagg
     1381 cggctggtta aaggctgcgc aacacactg
//
LOCUS       DAVBOG010000105         1056 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.106, whole genome shotgun sequence.
ACCESSION   DAVBOG010000105 DAVBOG010000000
VERSION     DAVBOG010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1056
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.106"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            97..504
                     /locus_tag="VQ865_002122"
     CDS             97..504
                     /locus_tag="VQ865_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013315450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HET3136396.1"
                     /translation="MARYGVYAVIPNPEQKQIVLVQEPNGAWFLPCGEIEAGENHQEA
                     LKRELIEELGFTAEIGTYYGQADEYFYSRHRDTYYYNPAYLYEATSFKEVQKPLENFN
                     HIAWFPIDEAIQNLKRGSHKWAIESWKKQHKID"
     gene            669..968
                     /locus_tag="VQ865_002123"
     CDS             669..968
                     /locus_tag="VQ865_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000767202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HET3136397.1"
                     /translation="MKLINTTNSHSQLVKSQLESTDATLVEVYSAGNTDVIFTQAPLH
                     YEILISNKHRAIREPEIETIQEFFLKRKIDKTSVDEANIKTLYSEKLIGISIPIK"
BASE COUNT          371 a          211 c          184 g          290 t
ORIGIN      
        1 tttggttcat ttcactataa taataacgat actagataat gaggaaaatg caatggcaaa
       61 cccaactttc ggagaaaaaa agcgaataca gactatattg ctcgctatgg cgtatatgca
      121 gttatcccta atcctgaaca aaaacaaatt gttcttgttc aagaaccaaa tggtgcttgg
      181 ttcctaccat gtggagaaat tgaagcaggt gaaaatcatc aggaagccct aaagcgtgag
      241 ttgattgaag agcttggttt cacagcagaa attggtacct attacggaca agctgacgaa
      301 tatttctatt ctcgtcatcg tgatacctac tactacaatc ctgcctacct ctatgaagca
      361 acttctttca aagaagtaca aaagccacta gaaaacttta atcatattgc ctggttccct
      421 attgacgagg ctatccaaaa ccttaaacgt ggtagccata aatgggccat tgaatcttgg
      481 aaaaaacagc ataagattga ctaatactct tcgaaaataa aatttaaacc acgtcagcgt
      541 cgccttaccg tactcaagta tagcctgcgg ctagcttcct agtttgctct ttgattttca
      601 ttgagtataa atcaagcgac tttattcaaa aagtgctata atagaattag aaaatcggag
      661 gaaatattat gaagcttatc aatacgacaa actcacactc gcaacttgta aaaagtcagc
      721 tagaaagtac cgatgcaacc cttgttgagg tttattctgc agggaataca gatgttattt
      781 ttacccaagc tccgcttcac tatgaaatcc tcatctcaaa caaacaccgt gctattcgtg
      841 agcctgaaat cgaaaccatt caagaatttt tcttgaaacg taaaattgat aagacctctg
      901 ttgatgaagc caatatcaag acactctact cagagaaatt aattggaatt tcaatcccaa
      961 tcaagtaaga aaattgagta aaaactcgat ttgagagaaa gtccaataag tctttccata
     1021 ataaaacgca tagtagcagg tgccgaaatg aactgc
//
LOCUS       DAVBOG010000106         1010 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.107, whole genome shotgun sequence.
ACCESSION   DAVBOG010000106 DAVBOG010000000
VERSION     DAVBOG010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 1010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1010
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.107"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..606)
                     /locus_tag="VQ865_002124"
                     /pseudo
     CDS             complement(1..606)
                     /locus_tag="VQ865_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            848..>1010
                     /locus_tag="VQ865_002125"
     CDS             848..>1010
                     /locus_tag="VQ865_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001849103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HET3136398.1"
                     /translation="MIIQLSDLGQVHLVCSKIDMRQGIDSLAYVVKTHFELDPFSGQV
                     FLFCGGRKDR"
BASE COUNT          292 a          193 c          159 g          366 t
ORIGIN      
        1 aatccgacga taaccataat ttcccttgtg ttcgataaaa atggattgaa tttcagcttt
       61 aagctcttgg tccttatctg ttttatctag ctgtttcaag tgatagtagt aggtcgaacg
      121 agctagttta atggctttta gaagaatatc taacgaaaac tcagtcatta attcttgaac
      181 aatttctgtc tttcttcttt ctctttttcc tccttcaatc ggagttctct taactttttt
      241 aggatggcat tttccgctct caggtactct ccctcttgtt ttctcaacaa tagtataccc
      301 gtttttcctg tattgtgcta gccagttaag aagtatcgta cgacttggga gacagtattc
      361 aagagaaact ctatctttag tccagccttc atgtcagact ttattaatca tttcttgttt
      421 taaatcagga gaatagtaac gattttttcc ttttttgacg aactctattc cgtaacgatc
      481 aatcaattta atcatatacc taagattaga attgtttatc ccaaatttat ttgaaagctt
      541 ctctaagcta tatccttgtt ttctaagttc atagatctga actttatcat cataactcaa
      601 tttcataata aaaacacccc aaaagttaga ttttttctgt ctaacttttg gggggcagtt
      661 cattctacac ccactattat gcgtttttat cattttgaaa tctactgcta atcaatgaag
      721 aagcaaagat caaactaggc agctagttac aagttacgta agcgcgtcat aacaaggtat
      781 ctatcctaat tccccaactt ccagtatact agataaaaaa taattatcgg aggaaaggta
      841 ttgtactatg ataattcaac taagtgattt aggtcaagtt caccttgttt gtagcaagat
      901 agatatgagg cagggaatag actcattagc ctatgtagtt aaaacccact ttgaattgga
      961 tcctttctcc ggtcaagtct ttctcttttg tggtggacgt aaagaccgct
//
LOCUS       DAVBOG010000107          996 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.108, whole genome shotgun sequence.
ACCESSION   DAVBOG010000107 DAVBOG010000000
VERSION     DAVBOG010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 996)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 996)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..996
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.108"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..125
                     /locus_tag="VQ865_002126"
     CDS             <1..125
                     /locus_tag="VQ865_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014947343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA cytosine methyltransferase"
                     /protein_id="HET3136399.1"
                     /translation="RKVSSNSQLYKQAGNSVTVPVIAAIAKKLKEIEEKDESIK"
     gene            109..558
                     /locus_tag="VQ865_002127"
     CDS             109..558
                     /locus_tag="VQ865_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000645893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136400.1"
                     /translation="MKALNKESILDCDELETELHDAEIKQLDEQLFLMPNYPCEFEVT
                     FLDDYHKKHNYPLFYESYLQNVMEFLESQDIKNGVDAFVDDHQNLVFVLYGQGYRAEG
                     KEGILTTQVTVKAYDEDKKPINFANLLDSLIVSEYQMEPNLWKVSHD"
     gene            551..931
                     /locus_tag="VQ865_002128"
     CDS             551..931
                     /locus_tag="VQ865_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000565031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136401.1"
                     /translation="MIDLYLSKNSQRNQLLLDFFQKYGIEVTPHSISEMTKDKLIEMM
                     SYSSDCFEFLSPNLLRFKNRDNLRLTDFIEMILKNPELCIRLPLAVSNKRVYPNLNLE
                     EARALLPRDTKQLIYMAQTHYLSS"
BASE COUNT          365 a          156 c          177 g          298 t
ORIGIN      
        1 ctagaaaagt ctctagtaat agtcagctct ataaacaagc tggtaatagt gtaaccgttc
       61 ctgtgattgc cgcaatcgca aagaaattaa aagaaataga ggaaaaagat gaaagcatta
      121 aataaagaat caatactaga ttgtgatgaa ttagaaacag aattacatga tgcagaaatc
      181 aaacagctgg atgaacaatt atttttgatg cccaattatc catgtgagtt tgaagtaaca
      241 tttttagatg attaccataa aaaacacaac tacccactat tttacgagtc ctatcttcaa
      301 aacgttatgg aattccttga aagtcaagac ataaagaatg gggttgatgc ctttgtagat
      361 gatcatcaaa atctcgtttt tgttttatat ggacaaggct atcgagcaga gggaaaagag
      421 ggaatactta caactcaagt aactgtaaaa gcttatgatg aagacaagaa accgattaac
      481 ttcgcaaatt tattagattc cttaatcgtc tcagaatatc aaatggaacc gaatctttgg
      541 aaggtctccc atgattgatc tctatctaag taaaaatagc caaagaaatc aacttctttt
      601 ggatttcttt caaaagtatg gcatagaggt cactcctcat tctatttctg aaatgacaaa
      661 ggacaaatta attgaaatga tgagctattc ttcagattgt tttgagtttc tatctcccaa
      721 tttattacga tttaagaacc gtgacaatct aagattaacg gatttcattg aaatgatatt
      781 aaaaaatcct gaactatgca tcaggcttcc tcttgcggtt tcaaataaga gagtttatcc
      841 aaatctgaat ttggaagagg ctagagctct attgccaaga gatacgaaac aattgattta
      901 catggcacaa acacattatt tatctagtta aaggagaagc aatatggctg aacgattttg
      961 ggagaacttg tccattattt tggctgaaag aaatat
//
LOCUS       DAVBOG010000108          994 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.109, whole genome shotgun sequence.
ACCESSION   DAVBOG010000108 DAVBOG010000000
VERSION     DAVBOG010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 994)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 994)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..994
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.109"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..99
                     /locus_tag="VQ865_002129"
     CDS             <1..99
                     /locus_tag="VQ865_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001828718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin transporter"
                     /protein_id="HET3136402.1"
                     /translation="FKRVGIFDGKAVEVTLREPYSRDLLQVVKSIK"
     gene            complement(396..683)
                     /locus_tag="VQ865_002130"
                     /pseudo
     CDS             complement(396..683)
                     /locus_tag="VQ865_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            682..945
                     /locus_tag="VQ865_002131"
                     /pseudo
     CDS             682..945
                     /locus_tag="VQ865_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          365 a          155 c          174 g          300 t
ORIGIN      
        1 tttaaacgtg ttggtatctt tgatgggaaa gcagtagaag ttactcttcg agaaccttat
       61 tcgagagatc tactgcaggt tgtcaagtca ataaagtaac tgacaccacg agtataatta
      121 ttagaaacgt ggaatcttat taaattttat aataaatata ttaaatgaaa aattattaga
      181 tataaactta tgtaataaaa cattgaggaa ataataaaaa tctatgggta atgttctgaa
      241 agtactttta ggttaggaga gaaatataat gatttttgaa aattgattca aaaaatagcg
      301 aattgtagaa aacgcttaac aaatggtgta taatagactt ccagcgaaac aaaatatgct
      361 acaataaacc tatgaattat aaagtaacct tatactcatc tgtcttcaca aagcattcta
      421 gtccatctcc gattaacgat ggactttatc atctccttct ccagtccttg tatgacatct
      481 tccaaagttc gaaaggcttt attcttaaat ccacgtttac gaatctcttt ccacacttat
      541 tcaatggggt tcatttctgg tgtgtatgga ggaataaatg caaagccaat attagtcgga
      601 atctttaagg cacttgattt atgccatata gcattgtcca taacgaataa aagataatca
      661 tctggataag cttgtgaaag cttggctgac agtggttatc aagggctcat gaagatatat
      721 cttcaagcac aaactccacg taaatccagc aaactcaagc cgctaacagc tgaagataaa
      781 gcctataacc atgcgctatc taaggagaga agcaaggttg agaatatttt tgccaaagta
      841 aaaacgttta aaatgttttc aacaacctat cgaaatcatc gtaaacgctt cggattacga
      901 atgaatttga ttgctgatat tatcaatcat gaactaggat tctagttttg caggaagtct
      961 aataaatgta taagaaaaag gaggaaaaag gatg
//
LOCUS       DAVBOG010000109          835 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.110, whole genome shotgun sequence.
ACCESSION   DAVBOG010000109 DAVBOG010000000
VERSION     DAVBOG010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 835)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 835)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..835
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.110"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            452..>835
                     /locus_tag="VQ865_002132"
     CDS             452..>835
                     /locus_tag="VQ865_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000242196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HET3136403.1"
                     /translation="MVLDYFFDKNLVFCLEADNQEHLFDQVATLLEEREIVTPTYREA
                     LITREKSFPTGLDMEFLGKNLPNVAIPHTDIVHNLAEKVVVVRLEKPVTFHNMIAPDK
                     EVEVSLLFFIINNSSSSQTNILAQLM"
BASE COUNT          291 a          128 c          154 g          262 t
ORIGIN      
        1 tctagaatgt cttccaaacg tggaaactct cgtaaacaaa gaggttttag aggcctattt
       61 accgtggact aaagttgtac aagaaaagtg caaataagaa atctccagat taggaactat
      121 atatgagttc actaatctgg agatttttca atagacttcg ttattgggcg gttaggatat
      181 gatcactgac ttcgtcagtc ttatctacaa cctcaaaaca gtgttttgag caacctgcgg
      241 ctagcttcct agtttactct ttgattttca ttgagtatta gaacagaaaa aatgcttgga
      301 gtatttgttt gtgtgtttat ttttatataa caaactataa acaaaacaaa aatataaaaa
      361 aagagacaaa aaagaacaga aagtaattga caacggtttc atatagtgtt atacttatgg
      421 cataaagtta atggaaagaa gggaaaaact tatggtatta gattatttct ttgacaaaaa
      481 ccttgtgttt tgcttagaag cggataatca agaacatctc tttgatcagg ttgcaacttt
      541 attggaagaa cgagaaattg taactccaac ttatcgtgaa gccttgatca cgcgtgaaaa
      601 gtcatttcca actggtttag atatggaatt tctaggaaag aacttgccaa atgtagcgat
      661 tcctcacaca gatattgttc ataatctagc tgagaaagtg gtggttgttc gattagaaaa
      721 accagtaact tttcacaata tgatagctcc tgataaggaa gtagaagtat ccctactctt
      781 ctttattatt aacaattcaa gttcaagtca aacaaatatt ctggctcagt tgatg
//
LOCUS       DAVBOG010000110          765 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.111, whole genome shotgun sequence.
ACCESSION   DAVBOG010000110 DAVBOG010000000
VERSION     DAVBOG010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 765)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 765)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..765
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.111"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(74..147)
                     /locus_tag="VQ865_002133"
     tRNA            complement(74..147)
                     /locus_tag="VQ865_002133"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(111..113),aa:Arg,seq:acg)
     gene            complement(157..242)
                     /locus_tag="VQ865_002134"
     tRNA            complement(157..242)
                     /locus_tag="VQ865_002134"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(206..208),aa:Leu,seq:taa)
     gene            complement(250..321)
                     /locus_tag="VQ865_002135"
     tRNA            complement(250..321)
                     /locus_tag="VQ865_002135"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(287..289),aa:Gly,seq:gcc)
     gene            complement(344..416)
                     /locus_tag="VQ865_002136"
     tRNA            complement(344..416)
                     /locus_tag="VQ865_002136"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(381..383),aa:Thr,seq:tgt)
     gene            complement(435..516)
                     /locus_tag="VQ865_002137"
     tRNA            complement(435..516)
                     /locus_tag="VQ865_002137"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(480..482),aa:Leu,seq:tag)
     gene            complement(522..594)
                     /locus_tag="VQ865_002138"
     tRNA            complement(522..594)
                     /locus_tag="VQ865_002138"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(559..561),aa:Lys,seq:ttt)
     gene            complement(619..691)
                     /locus_tag="VQ865_002139"
     tRNA            complement(619..691)
                     /locus_tag="VQ865_002139"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(656..658),aa:Asp,seq:gtc)
     gene            complement(694..765)
                     /locus_tag="VQ865_002140"
     tRNA            complement(694..765)
                     /locus_tag="VQ865_002140"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(731..733),aa:Val,seq:tac)
BASE COUNT          195 a          225 c          168 g          177 t
ORIGIN      
        1 cgaacctgcg acaccttggt cccaaaccaa gtactctacc aagctgagct acttcccgag
       61 ttaaatagaa aaatgcaccc tagaggagtc gaacctctaa ccgcctgatt cgtagtcagg
      121 tactctatcc agttgagcta agggtgctcc atattatgcc gaggaccgga atcgaaccgg
      181 tacgatcgtt accaatcgca ggattttaag tcctgtgcgt ctgccagttc cgccaccccg
      241 gcctctctaa gcgaacgacg ggattcgaac ccgcgacccc caccttggca aggtggtgtt
      301 ctaccactga actacgttcg cactgttttc ttctatctaa aaatgccggc tacatgactt
      361 gaacacgcga ccctctgatt acaaatcaga tgctctacca actgagctaa gccggctcat
      421 ttgttatatc ttaatgcggg ttaagggact tgaaccccca cgccgttaag cgccagatcc
      481 taaatctggt gcgtctgcca attccgccaa acccgcatat atgacccgta ctgggctcga
      541 accagtgacc cattgattaa aagtcaattg ctctaccaac tgagctaacg agtctaaaat
      601 aacttgcgtt atcttaaacg gtcccgacgg gaatcgaacc cgcgatcttc gccgtgacag
      661 ggcgacgtga taaccgctac actacgggac ctttgggagt taacgggatc gaaccgctga
      721 ccctctgctt gtaaggcaga tgctctccca gctgagctaa actcc
//
LOCUS       DAVBOG010000111          758 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.112, whole genome shotgun sequence.
ACCESSION   DAVBOG010000111 DAVBOG010000000
VERSION     DAVBOG010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..758
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.112"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..>758
                     /locus_tag="VQ865_002141"
     CDS             <1..>758
                     /locus_tag="VQ865_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000187281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3136404.1"
                     /translation="DGSTQEIDVPYDIPDTWEWVRIKSIYWNFGQNKPEKSFRYIDTS
                     SIDRKKNIINYKNLQYLSPEQAPSRARKLVSQNSVLFSTVRPYLKNIAVVRELKEYLI
                     ASTAFIVLDTLLNETYLKYYLLSDNFINRVNNKSTGTSYPAINDYNFNLLLIALPPLS
                     EQQRIVEAIESALEKVDEYAESYNRLEQLDKEFPDKLKKSILQYAMQGKLVEQDPNDE
                     SVEVLLEKIRAEKQKLFEEGKIKKKDLDISIVSQ"
BASE COUNT          297 a          110 c          120 g          231 t
ORIGIN      
        1 tgatggaagt actcaagaaa ttgatgttcc ttatgatatt cctgatactt gggagtgggt
       61 gaggataaaa tcaatttatt ggaattttgg gcaaaataag ccagagaaat cctttaggta
      121 tatagatacg tctagtattg atagaaaaaa gaacataatc aactacaaaa atctacaata
      181 tctttcacct gaacaagcgc cttcccgtgc cagaaaatta gtttcgcaga atagtgtctt
      241 attttcaaca gttagaccat atctaaaaaa tattgctgta gttagagaac ttaaagagta
      301 tttgatagct agtacagcat ttattgtttt ggatacttta cttaacgaaa catatttgaa
      361 atattattta ttatcagata attttatcaa tcgtgttaat aataaatcta ctggaacaag
      421 ttatcctgca atcaatgatt ataattttaa tctattatta attgctctcc ccccactatc
      481 cgaacaacaa cgaatagtag aagcaatcga atcagcttta gaaaaagtag atgaatatgc
      541 tgaaagttat aatagactag aacagctaga taaagaattt ccagataaac taaaaaaatc
      601 tattcttcaa tatgctatgc aaggaaaatt agttgaacaa gacccaaatg atgaatcagt
      661 cgaagtttta cttgaaaaaa tacgagcaga aaaacaaaaa ctctttgaag aaggcaagat
      721 taaaaagaaa gatttggaca tttctattgt ttcccaag
//
LOCUS       DAVBOG010000112          757 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.113, whole genome shotgun sequence.
ACCESSION   DAVBOG010000112 DAVBOG010000000
VERSION     DAVBOG010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..757
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.113"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            3..305
                     /locus_tag="VQ865_002142"
     CDS             3..305
                     /locus_tag="VQ865_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000590570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HET3136405.1"
                     /translation="MIKILAACGAGVNSSHQIKSALEEELSNRGYDVHCDAVMVKDVN
                     EDLMKGYDIFTPIAATDLGFEPGIPVIEAGPILFCIPAMSVPVFDNIRLPAKQNMV"
     gene            313..757
                     /locus_tag="VQ865_002143"
                     /pseudo
     CDS             313..757
                     /locus_tag="VQ865_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105201.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          251 a          141 c          154 g          211 t
ORIGIN      
        1 aaatgattaa aattcttgct gcctgcggtg caggtgttaa ctcaagtcac caaattaaaa
       61 gtgctctaga agaagaactt tcaaaccgtg gttatgatgt tcactgtgat gcagttatgg
      121 tgaaagatgt aaacgaagac cttatgaaag gttacgatat ctttacacca atcgctgcaa
      181 cagaccttgg ttttgaacca ggtatcccag ttatcgaagc tgggccaatc ttattctgta
      241 tcccagcaat gagcgttcca gtatttgaca atattagact tcctgcgaaa caaaatatgg
      301 tatagtagtt ccatgaatta tgaagcaagt aaacaactaa ctgatgcacg atttaagcgt
      361 cttgttggtg ttcaacgcac gacttttgaa gagatattag ctgtattaaa aacagcttat
      421 caacttaaac acgcaaaagg tggacgaaaa cctaaattaa gcctagaaga ctttcttatg
      481 gccactcttc aatatgtgcg agaatatcga acttatgaag aaattgcggc tgattttggt
      541 atccacgaaa gcaacttaat ccgtcggagc cgatgggttg aagtaactct tgttcaaagt
      601 ggtgttacga tttcaagaac tcctctcagt tctgaggaca cggtaatgat tgatgcgacg
      661 gaagtacaaa tcaatcgccc taaaaaaaca attagcgaat tattctggta aaaagaaatt
      721 tcacgctatg aagtctcaag cgattgtcac aagtcaa
//
LOCUS       DAVBOG010000113          675 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.114, whole genome shotgun sequence.
ACCESSION   DAVBOG010000113 DAVBOG010000000
VERSION     DAVBOG010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.114"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            1..627
                     /locus_tag="VQ865_002144"
                     /pseudo
     CDS             1..627
                     /locus_tag="VQ865_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611577.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS630 family transposase"
BASE COUNT          228 a          119 c          136 g          192 t
ORIGIN      
        1 atgccacgtc cagaacatcc taagaaagca gacgctcaaa ccattgtcgc gtctaaaaat
       61 aaaatttcaa ttcaagaaga aaagaaagcg ctttaaaacc agtagacgtt ttcataaggt
      121 tcgcttgatg taccaagatg aggctggctt cggtagaatc agtaaactgg gatcttgttg
      181 gtctccaata ggagtaggtc cacatgtcca tagtcactat atacgagaat ttcgctattg
      241 ttatggaccc atacaggcga atcatttttc ttaatagctg gtggatgtaa tactgagtgg
      301 atgaacgtct ttttagaaga gctttcacaa gcttatccag atgattatct tttattcgtt
      361 atggacaatg ctatatggca taaatcaagt accttaaaga ttccgactaa tattggcttt
      421 gcatttattc ctccatacac accagagatg aaccccattg aacaagtgtg gaaagagatt
      481 cgtaaacgtg gatttaaaaa taaagccttt caaactttgg aagatgtcat gaatcaactt
      541 taagatatca tacaaggact ggagaaggag gtgataaagc ccatcgttaa tcggagatgg
      601 actagaatgc tttttgaaag cagatgagta taaaaagaaa gtcctcattt caatagaaat
      661 cacgactttc tgatg
//
LOCUS       DAVBOG010000114          630 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.115, whole genome shotgun sequence.
ACCESSION   DAVBOG010000114 DAVBOG010000000
VERSION     DAVBOG010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..630
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.115"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            47..408
                     /locus_tag="VQ865_002145"
                     /pseudo
     CDS             47..408
                     /locus_tag="VQ865_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000895063.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
BASE COUNT          207 a           76 c          119 g          228 t
ORIGIN      
        1 ggctagtttc ctagtttgct ctttggtttt cattgagtat aacacattgt tagaagttgg
       61 tttaaatttc ctaatcagtt tgttcacatt taccttcgat atattatatc ccatagttaa
      121 ggttggtcat acagatgatt atagtcatgg agccgtaaaa cttagtgttt ctttagttga
      181 caaagatgcc atgaaaaaat atctgtaact gtaataggat attttgaaat aaatatagat
      241 gaaaatatca ccgatattct atacgtaaat ggtactgcta ttctttgtcc ttatttacgt
      301 tctattgttt caatagtttc ggcaattgat agcagtgaag caatgttgct acctaccatt
      361 aatgttttag agttactaga taaatctcaa ccttttgaag aagaataatt tattagctca
      421 ctaaattgag ggtaaggaaa agtaaaagca gtaagaaaaa tgtcttgcat tatacagcaa
      481 ccttttggga atgagtagat ggattgaata aaatttgatt aagagtggat gatttatctg
      541 tagattatta ttggacagtt agtcttgaag tagtctaaga attaggttat aatcagtaga
      601 agccttgcta ataatgagga ggttagttta
//
LOCUS       DAVBOG010000115          601 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.116, whole genome shotgun sequence.
ACCESSION   DAVBOG010000115 DAVBOG010000000
VERSION     DAVBOG010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..601
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.116"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..>601
                     /locus_tag="VQ865_002146"
     CDS             <1..>601
                     /locus_tag="VQ865_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000700331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pneumococcal-type histidine triad protein"
                     /protein_id="HET3136406.1"
                     /translation="FDPAQITSRTANGVAVPHGDHYHFIPYSQLSPLEEKLARIIPLR
                     YRSNHWVPDSRPEQPSPQPTPEPSPSPQPAPNPQPAPSNPIDEKLVKEAVRKVGDGYV
                     FEENGVPRYIPAKDLSAETAAGIDSKLAKQESLSHKLGAKKTDLPSSDREFYNKAYDL
                     LARIHQDLLDNKGRQVDFEALDNLLERLKDVSSDKVKLV"
BASE COUNT          192 a          135 c          122 g          152 t
ORIGIN      
        1 ttttcgaccc agcgcaaatc acaagtcgaa ccgccaatgg tgttgctgta ccgcacggag
       61 accattatca ctttattcct tattcacaac tgtcaccttt ggaagaaaaa ttggctcgta
      121 ttattcccct tcgttatcgt tcaaaccatt gggtaccaga ttcaagacca gaacaaccaa
      181 gtccacaacc gactccggaa cctagtccaa gtccgcaacc tgcaccaaat cctcaaccag
      241 ctccaagcaa tccaattgat gagaaattgg tcaaagaagc tgttcgaaaa gtaggcgatg
      301 gttatgtctt tgaggagaat ggagttcctc gttatatccc agccaaggat ctttcagcag
      361 aaacagcagc aggcattgat agcaaactgg ccaagcagga aagtttatct cataagctag
      421 gagctaagaa aactgacctc ccatctagtg atagagaatt ttacaataag gcttatgact
      481 tactagcaag aattcatcaa gatttacttg ataataaagg tcgacaagtt gattttgagg
      541 ctttggataa cctgttggaa cgactcaagg atgtctcaag tgataaagtc aagttagtgg
      601 a
//
LOCUS       DAVBOG010000116          585 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.117, whole genome shotgun sequence.
ACCESSION   DAVBOG010000116 DAVBOG010000000
VERSION     DAVBOG010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 585)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 585)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..585
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.117"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(21..500)
                     /locus_tag="VQ865_002147"
     CDS             complement(21..500)
                     /locus_tag="VQ865_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000588926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3136407.1"
                     /translation="MIKELYEEVQGTVYKCRNEYYLHLWELSDWDQEGMLCLHELISR
                     EEGLVDDIPRLRKYFKTKFRNRILDYIRKQESQKRRYDKEPYEEVGEISHRISEGGLW
                     LDDYYLFHETLRDYRNKQSKEKQEELERVLSNERFRGRQRVLRDLRIVFKEFTIRTH"
BASE COUNT          152 a          136 c           76 g          221 t
ORIGIN      
        1 attttttttt gcatgactta ctagtgggta cggatagtaa actccttaaa cacaatgcgt
       61 aagtctctta atactctttg acgccctcga aatcgttcat tgcttaagac gcgttctagt
      121 tcttcttgtt tctctttact ttgtttgttt ctataatctc ttagtgtttc atgaaagaga
      181 taataatcat ctagccagag acccccctca cttatacgat gactgatctc tcccacttct
      241 tcatagggtt ctttatcgta tctacgcttc tgactttcct gcttacggat atagtctaaa
      301 attcgatttc gaaacttggt tttgaaatat ttccttaaac gtggaatatc gtctaccagt
      361 ccttcttctc tactaatcaa ttcatgtaag cagagcatgc cttcttggtc ccaatccgac
      421 aattcccata aatgaaggta atattcattt ctacacttat aaacagtccc ttggacttct
      481 tcatacaatt ctttaatcat aattttcccc tttctagata cagtctaaca gattagaaaa
      541 cacatttgtt ccattttctc cattctgttc cctttagctc ctaaa
//
LOCUS       DAVBOG010000117          546 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.118, whole genome shotgun sequence.
ACCESSION   DAVBOG010000117 DAVBOG010000000
VERSION     DAVBOG010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.118"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..>546)
                     /locus_tag="VQ865_002148"
     CDS             complement(<1..>546)
                     /locus_tag="VQ865_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380-like element ISSpn5 family transposase"
                     /protein_id="HET3136408.1"
                     /translation="KTGQYYLIKLKKNTVLSRLGDLSLPCPQDEDLTILPHSAYSETL
                     YQAGSWSHKRRVCQFSERKEGNLFYDVISLVTNMTSGTSQDQFQLYRGRGQAENFIKE
                     MKEGFFGDKTDSSTLIKNEVRMMMSCIAYNLYLFLKHLAGGDFQTLTIKRFRHLFLHV
                     VGKCVRTGRKQLLKLSSLYAYS"
BASE COUNT          149 a          108 c          132 g          157 t
ORIGIN      
        1 ggaataggca tagagactag acaatttgag gagctgcttg cgtcctgttc gaacacattt
       61 tcccaccacg tgaagaaaaa gatggcggaa gcgtttgatt gttaaagttt ggaagtcacc
      121 tccagctaga tgtttgagaa aaagatagag attgtaggcg atacagctca tcatcatacg
      181 aacttcgttt ttgattaagg ttgaactatc cgttttatcg ccaaaaaatc cctccttcat
      241 ctccttgatg aaattctcgg cttgaccacg tccacgataa agctgaaact ggtcttggct
      301 tgttccactc gtcatatttg taacgagaga aataacatcg tagaacaagt ttccttcttt
      361 tcgttcagag aactggcaga cacgacgctt gtgcgaccaa gatcctgctt gatagagagt
      421 ttctgagtag gcggagtggg gcaagatggt taagtcctca tcctgtgggc aagggaggga
      481 aaggtctcca agacggctca gaacagtatt tttcttgagt tttatgaggt agtattgccc
      541 tgtttt
//
LOCUS       DAVBOG010000118          536 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.119, whole genome shotgun sequence.
ACCESSION   DAVBOG010000118 DAVBOG010000000
VERSION     DAVBOG010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 536)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 536)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..536
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.119"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(<1..534)
                     /locus_tag="VQ865_002149"
     CDS             complement(<1..534)
                     /locus_tag="VQ865_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004258578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HET3136409.1"
                     /translation="MEQIKDGIIVSCQALPHEPLYTEAGGVIPLLVKAAEQGGAVGIR
                     ANSVRDIKEIKEVTKLPIIGIIKRDYPPQEPFITATMKEVDELAELDIEVIALDCTKR
                     ERYDGLEIQEFIRQVKEKYPNQLLMADTSIFEEGLAAVEAGIDFVGTTLSGYTSYSPK
                     VDGPDFELIKKLCDAGVD"
BASE COUNT          141 a          133 c          103 g          159 t
ORIGIN      
        1 atctacaccg gcatcacaga gtttcttaat caattcaaaa tctggaccgt ctacttttgg
       61 actgtaggat gtgtagcctg ataaggttgt tccgacaaag tcaattcctg cttctacagc
      121 tgctagccct tcttcgaaga tactagtatc agccatcaaa agctgattag gatatttctc
      181 cttaacctga cgaatgaact cttgaatttc caaaccatcg tagcgttcac gcttggtaca
      241 atccagagca atcacctcga tgtccagttc tgccaattca tcaacttctt tcatagtagc
      301 cgtgatgaag ggttcctgag gtggataatc acgtttgata atcccaatga ttggaagttt
      361 agtgacttcc ttaatttcct tgatatcgcg aacactgttt gctcggatac cgactgctcc
      421 accttgctca gccgctttga ccagcaaggg aatcacccct cccgcttctg tataaagcgg
      481 ttcatgagga agagcctgac aagaaacgat gattccatct ttgatttgct caatca
//
LOCUS       DAVBOG010000119          501 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.120, whole genome shotgun sequence.
ACCESSION   DAVBOG010000119 DAVBOG010000000
VERSION     DAVBOG010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.120"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..>501
                     /locus_tag="VQ865_002150"
     CDS             <1..>501
                     /locus_tag="VQ865_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000756162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HET3136410.1"
                     /translation="FGENKIFESIDNLFDIIDGDRGKNYPKSDELFSEEYCLFLNTKN
                     VTKNGFSFDTKQFITKTKDKLLRKGKLERYDIVLTTRGTVGNVAYYDELIKYKHLRIN
                     SGMVILRPKTPNLNQKFIIHVLRNNNYSRVISGSAQPQLPITKLKKILLPLPPLALQN
                     EFADFVV"
BASE COUNT          191 a           75 c           83 g          152 t
ORIGIN      
        1 gtttggggaa aataaaatat ttgaaagcat tgataactta tttgatatta tagatggtga
       61 taggggcaaa aattatccta aatcagatga gttgtttagt gaggagtact gtttattttt
      121 aaatacaaag aatgttacta aaaacggatt ttcattcgat acaaagcaat ttatcactaa
      181 aacaaaggat aaattacttc gaaaaggcaa acttgagcgt tatgatatag tcttgacaac
      241 aagaggtact gttggaaatg tagcgtacta cgatgaatta ataaaatata aacatttacg
      301 tataaattca ggtatggtaa tattacgtcc caagacacca aatctaaatc agaaatttat
      361 tatccatgtt ttaaggaata ataattatag tcgagtgata tcaggaagtg ctcagcctca
      421 gttaccaatt acaaaattaa aaaaaatact tctccccctc cccccactag ccctccaaaa
      481 tgagttcgca gactttgtag t
//
LOCUS       DAVBOG010000120          476 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.121, whole genome shotgun sequence.
ACCESSION   DAVBOG010000120 DAVBOG010000000
VERSION     DAVBOG010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 476)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 476)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..476
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.121"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(91..228)
                     /locus_tag="VQ865_002151"
     CDS             complement(91..228)
                     /locus_tag="VQ865_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HET3136411.1"
                     /translation="MNPDRAEEYFCRGCQGENPEDIEFYDEQLQAEKVEALNIRLEVK
                     N"
     gene            complement(372..446)
                     /locus_tag="VQ865_002152"
                     /pseudo
     CDS             complement(372..446)
                     /locus_tag="VQ865_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000410533.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope"
BASE COUNT          170 a           79 c           69 g          158 t
ORIGIN      
        1 tatgtgcttc aagtatataa aaaggcgtaa aaatacgcct atagataatg gggttgaaat
       61 aggtttattg ttgatgagat tgtagataat tcaatttttt acttccaatc gaatattcaa
      121 agcctccacc ttttctgcct gtaattgttc atcataaaat tcaatatctt caggattttc
      181 cccttgacaa cctcggcaga aatattcttc cgctcgatca ggattcaaaa atcgacaagc
      241 acaaacaaaa cagtcgccat catcatttat tgagataata tagtagattg aaataagatg
      301 taaacaaatc gattaggaaa gttaaattaa tttctagaaa tttttagcag atgtagtgta
      361 ctattctagt ctcaatttac tatggcttca aatatatctt tcgaaaaaat atttacagat
      421 gtgtaatttt gaagcttgca aaagttagcc ccaattattc acccctaatc taaaaa
//
LOCUS       DAVBOG010000121          377 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.122, whole genome shotgun sequence.
ACCESSION   DAVBOG010000121 DAVBOG010000000
VERSION     DAVBOG010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..377
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.122"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            complement(1..377)
                     /locus_tag="VQ865_002153"
                     /pseudo
     CDS             complement(1..377)
                     /locus_tag="VQ865_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611512.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
BASE COUNT          100 a           67 c           71 g          139 t
ORIGIN      
        1 agtacttact ggaatggcaa attcagtcac atctgtgtag cactgttcca ttgttttaga
       61 gccttcaaat tggccttgaa tgagattctc tgccttcttg ccaacgtctc ctttaatgag
      121 aagaatattt tcgtttctgt cgcgttttag cttgtaaatt gagtactttc atcaagcctt
      181 gaactctttt atgatttacc agataagcac gatttcttag ttctaaatga atacagcgat
      241 aagcataatt tcccttgtgt tcgataaaaa tggattgaat ttcagcttta agctcttggt
      301 ccttatctgg tttgtctagc tgtttcaagt gatagtagta ggtccaacga gctagtttaa
      361 tagcttttag aagaaga
//
LOCUS       DAVBOG010000122          297 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.123, whole genome shotgun sequence.
ACCESSION   DAVBOG010000122 DAVBOG010000000
VERSION     DAVBOG010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 297)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 297)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.123"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            116..>297
                     /locus_tag="VQ865_002154"
     CDS             116..>297
                     /locus_tag="VQ865_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001808790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1380 family transposase"
                     /protein_id="HET3136412.1"
                     /translation="MNSLPNHHFQNKSFYQLSFDGGHLTQYGGLIFFQELFSQLKLKE
                     RISKYLVTNDQRRYCR"
BASE COUNT           95 a           57 c           49 g           96 t
ORIGIN      
        1 cttagatcct ggatggtttc ttttttcacc caatgggtgt tttttactag acaaaaaaga
       61 gtttcccctt tatggtataa gtgtagaaaa aaacacaaaa agaaaggaaa ctcacatgaa
      121 cagtttacca aatcatcact tccaaaacaa gtctttttac caactatctt tcgatggagg
      181 tcatttaacc cagtatggtg gtcttatctt ttttcaggaa cttttttccc agttgaaact
      241 aaaagagcgg atttctaagt atttagtaac gaatgaccaa cgccgctact gtcgtta
//
LOCUS       DAVBOG010000123          284 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.denovo.124, whole genome shotgun sequence.
ACCESSION   DAVBOG010000123 DAVBOG010000000
VERSION     DAVBOG010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..284
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.denovo.124"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
BASE COUNT           86 a           55 c           79 g           64 t
ORIGIN      
        1 tctgaggtgt aagtcctcgg tgggcacctg ttaccggtga acccaatagc gattcccaag
       61 cctgactatc gtgaggtagc ggattaaaac ggtctgggga tagaccgttt taaatctgac
      121 gctggaaata agaatcgtca gaggaaggga tagcgaactc gtggctctac gaacaggaac
      181 gtgatagtaa ggcgtatata gcggataagg gggcctcaaa ctctaaagtt caaaaaggta
      241 gtcgtaacct atatgcgtaa atcacgagag caactgaatt tgtc
//
LOCUS       DAVBOG010000124        10365 bp    DNA     linear   BCT 11-JAN-2024
DEFINITION  TPA_asm: Streptococcus pneumoniae strain NIG 382-05
            SAMEA1012538-rid20179113.guided.067, whole genome shotgun sequence.
ACCESSION   DAVBOG010000124 DAVBOG010000000
VERSION     DAVBOG010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMEA1012538
            Sequence Read Archive: ERR046726
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Streptococcus pneumoniae
  ORGANISM  Streptococcus pneumoniae
            Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
            Streptococcus.
REFERENCE   1  (bases 1 to 10365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (12-NOV-2023) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 12-NOV-2023
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001979945.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001979945.1
            Genome Coverage       :: 342x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 11/13/2023 02:22:47
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 2,165
            CDSs (total)                      :: 2,121
            Genes (coding)                    :: 1,986
            CDSs (with protein)               :: 1,986
            Genes (RNA)                       :: 44
            rRNAs                             :: 1, 1 (16S, 23S)
            complete rRNAs                    :: 1, 1 (16S, 23S)
            tRNAs                             :: 39
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 135
            CDSs (without protein)            :: 135
            Pseudo Genes (ambiguous residues) :: 0 of 135
            Pseudo Genes (frameshifted)       :: 80 of 135
            Pseudo Genes (incomplete)         :: 54 of 135
            Pseudo Genes (internal stop)      :: 35 of 135
            Pseudo Genes (multiple problems)  :: 29 of 135
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10365
                     /organism="Streptococcus pneumoniae"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMEA1012538-rid20179113.guided.067"
                     /strain="NIG 382-05"
                     /db_xref="taxon:1313"
     gene            <1..2002
                     /locus_tag="VQ865_002155"
     CDS             <1..2002
                     /locus_tag="VQ865_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017646277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HET3136413.1"
                     /translation="SRYPLENYQLDFYVDNSWGWLPWNWSDGIGKQVMYGLYAITNFI
                     WTISLYVSNATGYLVQEAYSLDFISATADSIGKNMQTLAGVSANGFSTEGFYVGFLLL
                     LILVLGVYVAYTGLIKRETTKAIHAIMNFVLVFILSASFIAYAPDYIKKINDFSSDIS
                     NASLSLGTKIVMPHSDSQGKDSVDLIRDSLFSIQVQQPWLLLQYNSSDIESIGIDRVE
                     SLLSTSPDSNNGEDREKIVAEEIEDRSNTNLTITKTINRLGTVFFLFVFNIGISIFVF
                     LLTGIMIFSQVLFIIYAMFLPVSFILSMIPSFDGMSKRAITKLFNTILTRAGITLIIT
                     TAFSISTMLYTLSAGYPFFLIAFLQIVTFAGIYFKLGDLMSMFSLQSNDSQSVGSRVM
                     RKPRMLMHAHMHRLQRKLGRSMTTLGAGSAIVTGKKGQSGSGSSARTQADHSRPDGKE
                     KSTLGKRIGQTIGTVADTKDRMVDTASGLKEQVKDLPTNARYAVYQGKSKVKENVRDL
                     TSSISQTKADRASGRKEQQEQRRKTIAKRRSEMEQVKQKKQPASSVHERPTTRQEQYH
                     DEQTSKQSNIQTSYKESQQAKQERPAVKSDFSSPKVERQGNTVQEKTVQKPATSTTTA
                     DRTSQRPITKERPSTVQRVPLQNTRSRPPIKTATIKKVGKKP"
     gene            1999..3000
                     /locus_tag="VQ865_002156"
     CDS             1999..3000
                     /locus_tag="VQ865_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018368130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HET3136414.1"
                     /translation="MKLKTLVIGGSGLFLMVFSLLLFVAILFSDEQDSGISNIHYGGV
                     NVSAEVLAHKPMVEKYAKEYGVEEYVNILLAIIQVESGGTAEDVMQSSESLGLPPNSL
                     STEESIKQGVKYFSELLASSERLSVDLESVIQSYNYGGGFLGYVANRGNKYTFELAQS
                     FSKEYSGGEKVSYPNPIAIPINGGWRYNYGNMFYVQLVTQYLVTTEFDDDTVQAIMDE
                     ALKYEGWRYVYGGASPTTSFDCSGLTQWTYGKAGINLPRTAQQQYDVTQHIPLSEAQA
                     GDLVFFHSTYNAGSYITHVGIYLGNNRMFHAGDPIGYADLTSPYWQQHLVGAGRIKQ"
     gene            2997..3932
                     /locus_tag="VQ865_002157"
     CDS             2997..3932
                     /locus_tag="VQ865_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002989471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HET3136415.1"
                     /translation="MRKEDLMMKFRKNQNKEKQIPKEKKPRVYYKVNPHKKVVIALWV
                     LLGLSFSFAIFKHFTAIDTHTIHETTIIEKEYVDTHHVENFVENFAKVYYSWEQSDKS
                     IDNRMESLKGYLTDELQALNVDTVRKDIPVSSSVRGFQIWTVEPTGDNEFNVTYSVDQ
                     LITEGENTKTVHSAYIVSVYVDGSGNMVLVKNPTITNIPKKSSYKPKAIESEGTVDSI
                     TTNEINEFLTTFFKLYPTATASELSYYVNDGILKPIGKEYIFQELVNPIHNRKDNQVT
                     VSLTVEYIDQQTKATQVSQFDLVLEKNGSNWKIIE"
     gene            4177..4293
                     /locus_tag="VQ865_002158"
     CDS             4177..4293
                     /locus_tag="VQ865_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HET3136416.1"
                     /translation="MILKYPENICMLCMPMVMHKNPSDKSIYHWDFYALLGF"
     gene            4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ865_002159"
     CDS             4309..6228
                     /gene="tet(M)"
                     /locus_tag="VQ865_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HET3136417.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDRGTTKTD
                     NTLLERQRGITIQTAITSFQWKNTKINIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKIGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     HPNMRVMNFTESEQWDMVIEGNDYLLEKYTSGKLLEALELEQEESIRFHNCSLFPVYH
                     GSAKNNIGIDNLIEVITNKFYSSTHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLH
                     LRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLG
                     KVQMEVTCALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVA
                     PLPLGSGVQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPKYCANIV
                     DTQLKNNEVILSGEIPARCIQEYRSDLTSFTNGRSVCLTELKGYHVTTGEPVCQPRRP
                     NSRIDKVRYMFNKIT"
     gene            6347..6514
                     /locus_tag="VQ865_002160"
     CDS             6347..6514
                     /locus_tag="VQ865_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HET3136418.1"
                     /translation="MCPVCGNKTRLKIREDTELKKFPLYCPKCRQENLIEIKQFKVTV
                     ITEPDAKTQSR"
     gene            complement(6574..6927)
                     /locus_tag="VQ865_002161"
     CDS             complement(6574..6927)
                     /locus_tag="VQ865_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3136419.1"
                     /translation="MRKKEDKYDFRAFGLAIKEARLKRGLTREQVGALIEIDPRYLTN
                     IENKGQHPSIQVLYDLVSLLHVSVDEFFLPANNLVKSTRRLQIEKYMDSFTDKELSLM
                     ESLASGINEARNIED"
     gene            7432..7854
                     /locus_tag="VQ865_002162"
     CDS             7432..7854
                     /locus_tag="VQ865_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HET3136420.1"
                     /translation="MKPSSFQTTIENQFDYICKRAMEDERKNYMLYLSRIAKREVSFS
                     DVGDYLVSQFATTDNYSTDFQIFTLNGLSVGVENDLLSEALRELPDKKREILLLFYFM
                     DMSDSEIADLLKLNRSTVYRHRTSGLALIKKFMEEFEE"
     gene            7851..8081
                     /locus_tag="VQ865_002163"
     CDS             7851..8081
                     /locus_tag="VQ865_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HET3136421.1"
                     /translation="MKTQYPMIPFPLIVKATDGDTEAINQILHHYRGYITKRSLRLMK
                     DEYGNQSMVVDEVLRGRMETRLITKILSFEIK"
     gene            8542..8745
                     /locus_tag="VQ865_002164"
     CDS             8542..8745
                     /locus_tag="VQ865_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006730246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HET3136422.1"
                     /translation="MKQTDIPIWERYTLTIEEASKYFRIGENKLRRLAEENKNANWLI
                     MNGNRIQIKRKQFEKIIDTLDAI"
     gene            8827..10044
                     /locus_tag="VQ865_002165"
     CDS             8827..10044
                     /locus_tag="VQ865_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020220015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HET3136423.1"
                     /translation="MSEKRRDNKGRILKTGESQRKDGRYLYKYIDSFGEPQFVYSWKL
                     VATDRVPAGKRDCISLREKIAELQKDIHDGIDVVGKKMTLCQLYAKQNAQRPKVRKNT
                     ETGRKYLMDILKKDKLGVRSIDSIKPSDAKEWAIRMSENGYAYQTINNYKRSLKASFY
                     IAIQDDCVRKNPFDFQLKAVLDDDTVPKTVLTEEQEEKLLAFAKADKTYSKNYDEILI
                     LLKTGLRISEFGGLTLPDLDFENRLVNIDHQLLRDTEIGYYIETPKTKSGERQVPMVE
                     EAYQAFKRVLANRKNDKRVEIDGYSDFLFLNRKNYPKVASDYNGMMKGLVKKYNKYNE
                     DKLPHITPHSLRHTFCTNYANAGMNPKALQYIMGHANIAMTLNYYAHATFDSAMAEMK
                     RLNKEKQQERLVA"
BASE COUNT         3475 a         1839 c         2093 g         2958 t
ORIGIN      
        1 cagccgatac ccacttgaaa actatcaact ggatttttat gtggataata gctggggctg
       61 gcttccgtgg aactggtcgg acgggattgg aaaacaggtc atgtatggac tatatgccat
      121 taccaatttt atttggacaa tcagtttgta tgtttccaat gcgacaggtt acttagtaca
      181 ggaagcctat tccttagact tcatttccgc tacagcagat tccattggta agaatatgca
      241 gaccttagct ggtgtgagtg caaacggatt ttcaacagag ggtttctatg ttggattcct
      301 cttactcttg attttggttc ttggggttta tgttgcctat acgggactga taaagagaga
      361 aaccacaaag gcaattcatg ccattatgaa ttttgtgctg gtgtttatcc tatcggcttc
      421 ctttattgcc tacgctcccg actacattaa aaaaatcaat gacttttcat cagacatcag
      481 taatgccagt ttatcacttg gcacgaagat tgtcatgccc cattccgata gtcaaggcaa
      541 ggacagcgtg gacttaatca gagatagcct gttttccata caggttcagc aaccgtggct
      601 actgcttcaa tacaacagtt cagacattga aagtatcggt attgaccgtg tggaaagcct
      661 gctctccacc agcccagatt ccaacaatgg cgaagacaga gaaaaaattg ttgcggaaga
      721 aattgaagac agaagcaata ccaatctaac cattacaaag accattaacc gtttaggtac
      781 agtcttcttc ctatttgtct tcaatattgg gatttccata tttgtattcc tattaacagg
      841 aatcatgatt ttctcgcagg tactttttat catctatgct atgtttctgc ctgtgagctt
      901 tattttaagc atgattccat catttgatgg tatgtcaaaa cgagccataa caaagctctt
      961 taataccatt ttgacacgag ctggaatcac attgattatt acgacagcat ttagtatttc
     1021 aaccatgctc tataccttat cggctggtta tccgttcttt ttgattgctt ttctacagat
     1081 tgtgaccttt gcaggaatct acttcaagct gggcgattta atgagtatgt tttctctaca
     1141 gagtaacgat tctcaaagtg tgggaagtcg tgtgatgaga aaacctcgta tgcttatgca
     1201 cgctcacatg caccgtctac agcggaaact tggacgttcc atgactactc taggggctgg
     1261 gtctgccatt gttacaggta aaaaaggaca gtcgggttcg gggagttctg caaggacaca
     1321 agcagatcac tcccgaccag acggaaagga aaaatcaaca cttggaaaac gtatcggtca
     1381 aaccatcggt acagtagctg ataccaaaga cagaatggta gacactgcta gtggtttgaa
     1441 agaacaggtt aaagatttgc cgaccaatgc aagatatgca gtatatcaag gaaaatccaa
     1501 agtaaaagag aatgtccgtg atttaaccag tagtatttct caaaccaaag cggacagagc
     1561 cagtggacgc aaggaacagc aggaacaaag gcgaaaaacc attgcgaagc gtcgctctga
     1621 aatggaacag gtcaaacaga aaaaacagcc tgcttcttct gttcatgaaa gaccgactac
     1681 aagacaagaa caatatcatg atgaacagac ctcaaaacag tctaatattc agacttcata
     1741 taaggaatct caacaagcca aacaagagcg tccagcagtt aagtccgatt tttcaagtcc
     1801 aaaagtggaa cgccaaggca ataccgttca agaaaaaacc gttcaaaagc cagcaacttc
     1861 aaccactaca gcagatagaa cttcacaacg tccaatcaca aaagaacgtc cgtctactgt
     1921 tcaaagagta ccactacaaa atacaagaag tagaccacca atcaaaaccg ccaccattaa
     1981 gaaagtcggt aagaaaccat gaagttgaaa actttagtga ttggtggttc tggattattc
     2041 ttgatggtct tctcactgct tctgtttgtt gccattttat tttcagatga acaggacagc
     2101 ggaatttcca atattcatta tggaggtgtg aatgtttccg cagaagtgct ggctcataag
     2161 cctatggtag aaaaatatgc caaagaatat ggcgttgaag aatatgtcaa catacttctt
     2221 gcgattatac aggtggaatc gggcggtact gcggaagatg ttatgcagtc ctcggaatcc
     2281 ctcggtcttc cacctaattc attgagtaca gaagaatcca ttaagcaagg tgtgaagtat
     2341 ttcagtgaat tattagccag tagcgaaagg ctcagtgtag atttagaatc ggttatccag
     2401 tcctacaatt atggtggtgg tttcttaggg tatgtggcta atcgtggaaa taaatatacc
     2461 tttgaactgg ctcaaagttt ctcaaaagag tattcaggtg gcgaaaaagt gtcttacccc
     2521 aatcccatag ccatacctat caatgggggc tggcgataca actatggcaa tatgttttat
     2581 gtgcaactgg taacgcagta tcttgtcaca acagagtttg atgatgatac ggtacaagcc
     2641 atcatggacg aagcactgaa atatgagggc tggcgatacg tttacggtgg agcttccccg
     2701 actacttctt ttgattgtag cggactgaca caatggacgt atggaaaagc tggaattaac
     2761 ttaccacgaa ccgcacaaca gcaatatgat gtgacccagc atatcccact atcggaagca
     2821 caagctggcg atttggtttt ctttcattct acctataacg ctggctctta tattactcat
     2881 gttgggatat accttggcaa taaccgtatg tttcatgcag gcgacccaat cggttatgcc
     2941 gacttaacaa gcccctactg gcaacagcat ttagtgggag caggacgaat caaacaatga
     3001 gaaaggaaga tttaatgatg aaatttagaa aaaatcagaa taaagaaaaa cagataccaa
     3061 aggaaaagaa acctcgtgtc tactataagg tcaatcctca taaaaaggtt gtgattgcct
     3121 tgtgggtact tttagggctt agtttcagct ttgcgatatt caagcacttt acagctatag
     3181 atactcatac tattcacgaa acaactatca tagaaaagga atacgttgat actcatcatg
     3241 tagaaaattt tgtagagaac tttgcgaaag tctactattc atgggagcaa tccgataagt
     3301 ccattgataa tcgaatggaa agtctaaaag gctatctgac agatgaactt caagctctca
     3361 atgttgatac agtacgcaaa gatattcctg tatcgtcttc tgtaagagga tttcagatat
     3421 ggacggtaga gccaactggc gacaatgagt ttaatgtaac ctacagtgta gaccagctca
     3481 ttacagaggg agaaaataca aagaccgtcc actctgctta tatagtgagt gtctatgtag
     3541 atggttctgg aaatatggta ctggttaaga atccgaccat taccaacata cctaagaaat
     3601 caagttataa accaaaagcc attgaaagtg aggggacggt tgattccatt acaaccaatg
     3661 aaatcaatga gtttttaacg acgttcttca agctctatcc tacagcgaca gccagtgaac
     3721 tttcctacta tgtgaatgac gggatattaa aaccaatcgg aaaagagtac atctttcaag
     3781 aactggtaaa tcctattcac aatcgtaagg ataatcaagt cacggtatcg ctgacagtgg
     3841 agtatatcga ccagcagacc aaagcaacgc aggtatctca atttgatttg gtacttgaaa
     3901 agaacgggag taattggaag attatagaat aacaaatatt ggtacattat tacagctatt
     3961 ttgtaatcac gtactctctt tgataaaaaa ttggagattc ctttacaaat atgctcttat
     4021 gtgctattat ttaagtatct atttaaaagg agttaataaa tatgcggcaa ggtattctta
     4081 aataaactgt caatttgata gtggaaacaa ataattggat gtcctttttt aggagggctt
     4141 agttttttgt acccagttta agaatacctt tatcatgtga ttctaaagta tccggagaat
     4201 atctgtatgc tttgtatgcc tatggttatg cataaaaatc ccagtgataa gagtatttat
     4261 cactgggatt tttatgccct tttgggcttt tgaatggagg aaaatcacat gaaaattatt
     4321 aatattggag ttttagctca tgttgatgcg ggaaaaacta ccttaacaga aagcttatta
     4381 tataacagtg gagcgattac agaattagga agcgtggaca gaggtacaac gaaaacggat
     4441 aatacgcttt tagaacgtca gagaggaatt acaattcaga cggcgataac ctcttttcag
     4501 tggaaaaata ctaagataaa catcatagac acgccaggac atatggattt tttagcagaa
     4561 gtatatcgtt cattatcagt attagatggg gcaattctac tgatttctgc aaaagatggc
     4621 gtacaagcac aaactcgtat attgtttcat gcacttagga aaataggtat tcccacaatc
     4681 ttttttatca ataagattga ccaaaatgga attgatttat caacggttta tcaggatatt
     4741 aaagagaaac tttctgcgga aattgtaatc aaacagaagg tagaactgca tcctaatatg
     4801 cgtgtaatga actttaccga atctgaacaa tgggatatgg taatagaagg aaatgattac
     4861 cttttggaga aatatacgtc tgggaaatta ttggaagcat tagaactcga acaagaggaa
     4921 agcataagat ttcataattg ttccctgttc cctgtttatc acggaagtgc aaaaaacaat
     4981 atagggattg ataaccttat agaagtgatt acgaataaat tttattcatc aacacatcga
     5041 ggtcagtctg aactttgcgg aaaagttttc aaaattgagt attcggaaaa aagacagcgt
     5101 cttgcatata tacgtcttta tagtggcgta ctgcatttgc gagattcggt tagaatatcg
     5161 gaaaaggaaa aaataaaaat tacagaaatg tatacttcaa taaatggtga attatgtaaa
     5221 atcgataagg cttattccgg ggaaattgtt attttgcaga atgagttttt gaagttaaat
     5281 agtgttcttg gagatacaaa gctattgcca cagagagaga gaattgaaaa tcccctccct
     5341 ctgctgcaaa cgactgttga accgagcaaa cctcaacaaa gggaaatgtt acttgatgca
     5401 cttttagaaa tctccgacag tgacccgctt ctgcgatatt atgtggattc tgcgacacat
     5461 gaaatcatac tttctttctt agggaaagta caaatggaag tgacttgtgc tctgctgcaa
     5521 gaaaagtatc atgtggagat agaaataaaa gagcctacag tcatttatat ggaaagaccg
     5581 ttaaaaaaag cagagtatac cattcacatc gaagttccac cgaatccttt ctgggcttcc
     5641 attggtctat ctgtagcacc gcttccatta gggagcggag tacagtatga gagctcggtt
     5701 tctcttggat acttaaatca atcgtttcaa aatgcagtta tggaggggat acgctatggc
     5761 tgtgaacaag gattgtatgg ttggaatgtg acggactgta aaatctgttt taagtatggc
     5821 ttatactata gccctgttag taccccagca gattttcgga tgcttgctcc tattgtattg
     5881 gaacaagtct taaaaaaagc tggaacagaa ttgttagagc catatcttag ttttaaaatt
     5941 tatgcgccac aggaatatct ttcacgagca tacaacgatg ctcctaaata ttgtgcgaac
     6001 atcgtagaca ctcaattgaa aaataatgag gtcattctta gtggagaaat ccctgctcgg
     6061 tgtattcaag aatatcgtag tgatttaact tcctttacaa atggacgtag tgtttgttta
     6121 acagagttaa aagggtacca tgttactacc ggtgaacctg tttgccagcc ccgtcgtcca
     6181 aatagtcgga tagataaagt acgatatatg ttcaataaaa taacttagtg tattttatgt
     6241 tgttatataa atatggtttc ttgttaaata agatgaaata ttttttaata aagatttgaa
     6301 ttaaagtgta aaggaggaga tagttattat aaactacaag tggatattgt gtcctgtatg
     6361 tggaaataaa acacgattaa agataaggga agatactgaa ttaaaaaaat tccccctcta
     6421 ttgtccgaaa tgcagacaag aaaatttaat tgaaataaag cagttcaaag taactgtgat
     6481 tacagagcca gacgcaaaga cgcagagccg ataaaatgag attaatacaa tctcatttta
     6541 tcggctcttt ccgttatgta tggattcttt taattagtct tcgatgtttc ttgcttcgtt
     6601 gataccgctg gctaaagatt ccattaagga tagttctttg tctgtaaagc tatccatgta
     6661 tttctctatc tgtaatcgtc gggtgctttt taccaagtta ttagcaggta agaaaaattc
     6721 atcaacggaa acatgaagta acgatacaag gtcataaaga acttgtatgc tggggtgttg
     6781 ccctttattt tcaatattag ttaagtaccg tgggtcaatt tcaatcaatg ctcccacttg
     6841 ttcacgagtt aaacctcgtt tcaatcgagc ttctttaatg gctaaaccaa aggctctaaa
     6901 atcatattta tcttcttttt tacgcatagt agaccacctc tatacatttt attgttccta
     6961 ctgaattaaa aacaggtata gaaaaacgtg ttatatggtt tataggttta tatttaataa
     7021 aaagcactac taaacgccaa taaaaaaaac cgttatatgg tagtgctatt tacgctgtta
     7081 aaatattgta tattacttcc aaatggcggt ttgttggagg tcaacgtcgc catgaagtac
     7141 atcatataca ataaatttcc ttacattggg ttcttgtcaa aaaaagtcgt ctatctgcaa
     7201 tagataagta cgtccaccaa tgtggtttta taaatcatat agatagaata acagaagcat
     7261 gtaaacagag aaataaatct gtttatatgc ttttttggct attcagaact tttttacaaa
     7321 gtttatttat cagtaatgca acaaatcccc ctttcacatt gggactaaga gtgaaaggag
     7381 ataaacgagc aaggctcact tcctttccta gacagaaagg gggtgagaaa catgaaacca
     7441 tcttcttttc agaccacaat agaaaatcag tttgactata tctgtaaacg tgctatggaa
     7501 gacgagcgaa agaattatat gctttatctt tcaaggattg caaagcgtga ggtgtccttt
     7561 tcggatgttg gcgattatct tgttagccag tttgcgacaa cagataacta ttcaactgac
     7621 tttcagattt ttacactcaa tgggttatca gtaggcgttg aaaatgattt gttgagtgaa
     7681 gcattacgtg agttgccaga caagaaacgt gaaattctac tgctgtttta ctttatggac
     7741 atgagcgatt cagaaattgc agacctgttg aaattgaacc gttctactgt ctatcggcat
     7801 agaaccagtg gactagcctt aattaaaaag tttatggagg aatttgaaga atgaaaacac
     7861 aatatcctat gattcccttt cctctcattg taaaggcaac agatggcgat accgaagcga
     7921 ttaaccagat tctacatcat tacagagggt acataacgaa gcgttcccta cgacttatga
     7981 aagatgaata tggcaatcaa agtatggtcg ttgatgaagt cttacgtgga agaatggaaa
     8041 ccagactgat tacaaagatt ttgtcatttg aaattaagta atatcctctc tcctttcgtg
     8101 gaagcgtgct aaaccattcc acgcttcccg aacagggagg tttgttattc caccaaagca
     8161 tattgagctt tcaatgtgtt ttgataggct aacgagccat tgttctttga aaactgaata
     8221 aaagtaatcg aatacgtttc gataagaaaa gagccaacgg aactaaccgc catgacctat
     8281 cttataaaga tagcgagcga ttcatgttag tgatccgaga agcaatcttt agcaggattg
     8341 cctgcaacga cattcttatc gtgataatga tactcccata cagtcaatag tccgagcgtg
     8401 ataaaaccgt cgcaggcaat gagtatggct acatgagaac catgcagggg tggaactccc
     8461 gtgagctttg ctaaagctgt tcgattgctg gtaaaacaac ttttatgaaa tccaaataag
     8521 tgatttggaa aggaggattt tatgaagcag actgacattc ctatttggga acgttatacc
     8581 ctaaccattg aagaagcgtc aaaatatttt cgtattggcg aaaacaagct acgacgcttg
     8641 gcagaggaaa ataaaaatgc aaattggctg attatgaatg gcaatcgtat tcagattaaa
     8701 cgaaaacaat ttgaaaaaat tatagataca ttggacgcaa tctagcgtcg ccaaagggtc
     8761 ttgtatatga taaaatagta ttaagtcgta tcaaggctct ttccataaag gaaaggagca
     8821 aatgccatgt cagaaaaaag acgtgacaat aaaggtcgaa tcttaaagac tggagagagc
     8881 caacgaaaag acggaagata cttatacaaa tatatagatt catttggaga accgcaattt
     8941 gtttactcgt ggaaacttgt ggctacagac cgagtaccag caggaaagcg tgattgtatc
     9001 tcacttagag agaaaatcgc agagttacag aaagacattc atgatggtat tgatgttgta
     9061 ggaaagaaaa tgacactctg ccagctttac gcaaaacaga acgctcaaag accaaaggtt
     9121 agaaaaaaca ctgaaactgg acgcaaatat cttatggata ttttgaagaa agacaagtta
     9181 ggtgtaagaa gtattgacag tattaagcca tcagacgcta aagaatgggc tattagaatg
     9241 agtgaaaatg gttatgctta tcaaaccatc aataactaca aacgttcttt aaaggcttca
     9301 ttctatattg ctatacaaga tgattgtgtt cggaagaatc catttgactt tcaactgaaa
     9361 gcagttcttg atgatgatac tgtccctaag accgtactaa cagaagaaca ggaagaaaaa
     9421 ctgttagcct ttgcaaaagc tgataaaacc tacagcaaaa attatgatga aattttgata
     9481 ctcttaaaaa caggtcttcg tatttcagag tttggtggtt tgacacttcc agatttagat
     9541 tttgagaatc gtcttgtcaa tatagaccat cagctattga gagatactga aattgggtac
     9601 tacattgaaa caccaaagac caaaagtggc gaacgtcaag ttcctatggt tgaagaagcc
     9661 tatcaagcat ttaagcgagt gttagcgaat cgaaagaatg ataagcgtgt tgagattgat
     9721 ggatatagtg atttcctctt tcttaataga aagaactatc caaaagtggc aagtgattac
     9781 aacggcatga tgaaaggtct tgttaagaaa tacaataagt ataacgagga taaattgcca
     9841 cacatcactc cacatagttt gcgacataca ttctgtacca actatgcaaa tgcaggaatg
     9901 aatccaaagg cattacagta cattatggga catgctaata tagccatgac gctgaactat
     9961 tacgcacatg caacattcga ttctgcaatg gcagaaatga aacgcttgaa taaagagaag
    10021 caacaggagc gtcttgttgc ttagtagtac aaatgaattt actacttatt taccacttct
    10081 gacagctaag acatgaggaa atatgcaaag aaacgtgaag tatcttccta cagtaaaaat
    10141 actcgaaagc acatagaata aggctttacg agcatttaag aaaatataaa aagataatta
    10201 gaaatttata ctttgttttt attaaaaagc agcaaactat aaactagtag gttccacact
    10261 aaatgtagcc ccatactgcc ccacaagtcc gatttatagc gtaccatccc taaaaacatt
    10321 cccaatgaaa catataaaca ccaagctaga atggttcctg gatga
//
